Chemical Strategies With Documented Efficacy For P
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PaperHomotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
Full title: Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
PaperSolid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs.
Tailhades, Julien, Takizawa, Hotake, Gait, Michael J, Wellings, Don A, Wade, John D, Aoki, Yoshitsugu, Shabanpoor, Fazel · 2017 · Frontiers in chemistry · DOI
Full title: Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs.
Authors: Tailhades, Julien, Takizawa, Hotake, Gait, Michael J, Wellings, Don A, Wade, John D, Aoki, Yoshitsugu, Shabanpoor, Fazel
PaperFluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R
Jones, Jonathan-Lee, Harris, Paul W. R., Scanlon, Denis B., Forbes, Briony E., Brimble, Margaret A., Abell, Andrew D. · 2016 · Organic & Biomolecular Chemistry · DOI
Full title: Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R
Authors: Jones, Jonathan-Lee, Harris, Paul W. R., Scanlon, Denis B., Forbes, Briony E., Brimble, Margaret A., Abell, Andrew D.
PaperUltrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.
Silva, Rúben D M, Franco Machado, João, Gonçalves, Kyle, Lucas, Francisco M, Batista, Salete, Melo, Rita, Morais, Tânia S, Correia, João D G · 2021 · Molecules (Basel, Switzerland) · DOI
Full title: Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.
Authors: Silva, Rúben D M, Franco Machado, João, Gonçalves, Kyle, Lucas, Francisco M, Batista, Salete, Melo, Rita, Morais, Tânia S, Correia, João D G
ThesisStudies towards the chemical synthesis of the 18 kDa antigenic protein from Mycobacterium leprae : a thesis presented in partial fulfilment of the requirements for the degree of Ph. D. in Chemistry at Massey University
Love, Stephen George · 2013 · Massey University · DOI
Full title: Studies towards the chemical synthesis of the 18 kDa antigenic protein from Mycobacterium leprae : a thesis presented in partial fulfilment of the requirements for the degree of Ph. D. in Chemistry at Massey University
ThesisMilde C-Acylierungen zur Synthese von bis- und triselektrophilen Verbindungen sowie deren Umwandlung zu weiteren biologisch relevanten Verbindungen
El-Dahshan, Adeeb · 2009 · Freie Universität Berlin (Refubium) · DOI
Full title: Milde C-Acylierungen zur Synthese von bis- und triselektrophilen Verbindungen sowie deren Umwandlung zu weiteren biologisch relevanten Verbindungen
ThesisAn approach to the semisynthesis of acyl carrier protein : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemistry at Massey University
Prestidge, Ross Leonard · 2012 · Massey University · DOI
Full title: An approach to the semisynthesis of acyl carrier protein : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemistry at Massey University
ThesisChemical Studies Toward the Total Synthesis of Lagunamide A Incorporating the Application of Diastereoselective Vinylogous Mukaiyama Aldol Reaction via Kinetic Resolution Methodology
Singh, Simranjeet · 2021 · University of California, San Diego (UCSD) · DOI
Full title: Chemical Studies Toward the Total Synthesis of Lagunamide A Incorporating the Application of Diastereoselective Vinylogous Mukaiyama Aldol Reaction via Kinetic Resolution Methodology
ThesisSolid-phase synthesis of difficult purine-rich PNAs through selective hmb incorporation: Application to the total synthesis of cell penetrating peptide-PNAs
Tailhades, J; Takizawa, H; Gait, MJ et al. · 2020 · University of Melbourne · DOI
Full title: Solid-phase synthesis of difficult purine-rich PNAs through selective hmb incorporation: Application to the total synthesis of cell penetrating peptide-PNAs
Authors: Tailhades, J; Takizawa, H; Gait, MJ; Wellings, DA; Wade, JD; Aoki, Y; Shabanpoor, F
ThesisDisruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
Mimna, Richard; Camus, Marie-Stephanie; Schmid, Adrian et al. · 2007 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
ThesisDesign, Synthesis, Characterisation, and Biological Evaluation of Peptides Targeting Infectious Diseases: Host-Directed Therapy against Mycobacterium tuberculosis and Stapled Peptide Fusion-Inhibitors Targeting SARS-CoV-2
Sharma, Anuvratta Priyanka · 2025 · University of Auckland · DOI
Full title: Design, Synthesis, Characterisation, and Biological Evaluation of Peptides Targeting Infectious Diseases: Host-Directed Therapy against Mycobacterium tuberculosis and Stapled Peptide Fusion-Inhibitors Targeting SARS-CoV-2
ThesisFmoc-POAC: [(9-fluorenylmethyloxycarbonyl)-2,2,5,5-tetramethylpyrrolidine-N-oxyl-3-amino-4-carboxylic acid]: A novel protected spin labeled beta-amino acid for peptide and protein chemistry
Tominaga, M.; Barbosa, SR; Poletti, E. F. et al. · 2014 · Universidade Estadual Paulista (UNESP) · DOI
Full title: Fmoc-POAC: [(9-fluorenylmethyloxycarbonyl)-2,2,5,5-tetramethylpyrrolidine-N-oxyl-3-amino-4-carboxylic acid]: A novel protected spin labeled beta-amino acid for peptide and protein chemistry
Authors: Tominaga, M.; Barbosa, SR; Poletti, E. F.; Zukerman-Schpector, J.; Marchetto, Reinaldo [UNESP]; Schreier, S.; Paiva, ACMM; Nakaie, C. R.
ThesisExploring the Synthesis of Peptide Activated Serine Acylating Agents with Enhanced Lactamase Stability: Novel Surrogate β-Lactam Antibiotic-Peptide Hybrids
Gunukula, Venkata · 2025 · University of Auckland · DOI
Full title: Exploring the Synthesis of Peptide Activated Serine Acylating Agents with Enhanced Lactamase Stability: Novel Surrogate β-Lactam Antibiotic-Peptide Hybrids
PaperSequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils.
Wang, Shih-Ting, Lin, Yiyang, Spencer, Ryan K, Thomas, Michael R, Nguyen, Andy I, Amdursky, Nadav, Pashuck, E Thomas, Skaalure, Stacey C, Song, Cheng Yu, Parmar, Paresh A, Morgan, Rhodri M, Ercius, Peter, Aloni, Shaul, Zuckermann, Ronald N, Stevens, Molly M · 2017 · ACS nano · DOI
Full title: Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils.
Authors: Wang, Shih-Ting, Lin, Yiyang, Spencer, Ryan K, Thomas, Michael R, Nguyen, Andy I, Amdursky, Nadav, Pashuck, E Thomas, Skaalure, Stacey C, Song, Cheng Yu, Parmar, Paresh A, Morgan, Rhodri M, Ercius, Peter, Aloni, Shaul, Zuckermann, Ronald N, Stevens, Molly M
PaperN-terminal engineering of amyloid-β-binding Affibody molecules yields improved chemical synthesis and higher binding affinity.
Lindgren, Joel, Wahlström, Anna, Danielsson, Jens, Markova, Natalia, Ekblad, Caroline, Gräslund, Astrid, Abrahmsén, Lars, Karlström, Amelie Eriksson, Wärmländer, Sebastian K T S · 2010 · Protein science : a publication of the Protein Society · DOI
Full title: N-terminal engineering of amyloid-β-binding Affibody molecules yields improved chemical synthesis and higher binding affinity.
Authors: Lindgren, Joel, Wahlström, Anna, Danielsson, Jens, Markova, Natalia, Ekblad, Caroline, Gräslund, Astrid, Abrahmsén, Lars, Karlström, Amelie Eriksson, Wärmländer, Sebastian K T S
Year: 2010
Venue: Protein science : a publication of the Protein Society
PaperDepsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated technique via depsidipeptide units.
Coin, Irene, Dölling, Rudolf, Krause, Eberhard, Bienert, Michael, Beyermann, Michael, Sferdean, Calin Dan, Carpino, Louis A · 2006 · The Journal of organic chemistry · DOI
Full title: Depsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated technique via depsidipeptide units.
Authors: Coin, Irene, Dölling, Rudolf, Krause, Eberhard, Bienert, Michael, Beyermann, Michael, Sferdean, Calin Dan, Carpino, Louis A
PaperChallenges in Peptide Solubilization - Amyloids Case Study.
Polańska, Oliwia, Szulc, Natalia, Stottko, Rafał, Olek, Mateusz, Nadwodna, Julita, Gąsior-Głogowska, Marlena, Szefczyk, Monika · 2024 · Chemical record (New York, N.Y.) · DOI
Full title: Challenges in Peptide Solubilization - Amyloids Case Study.
PaperUsing a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes.
Wadhwani, Parvesh, Bürck, Jochen, Strandberg, Erik, Mink, Christian, Afonin, Sergii, Ulrich, Anne S · 2008 · Journal of the American Chemical Society · DOI
Full title: Using a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes.
Authors: Wadhwani, Parvesh, Bürck, Jochen, Strandberg, Erik, Mink, Christian, Afonin, Sergii, Ulrich, Anne S
PaperImproved Stability and Tunable Functionalization of Parallel β-Sheets via Multicomponent N-Alkylation of the Turn Moiety.
Ricardo, Manuel G, Moya, Celia G, Pérez, Carlos S, Porzel, Andrea, Wessjohann, Ludger A, Rivera, Daniel G · 2020 · Angewandte Chemie (International ed. in English) · DOI
Full title: Improved Stability and Tunable Functionalization of Parallel β-Sheets via Multicomponent N-Alkylation of the Turn Moiety.
Authors: Ricardo, Manuel G, Moya, Celia G, Pérez, Carlos S, Porzel, Andrea, Wessjohann, Ludger A, Rivera, Daniel G
Year: 2020
Venue: Angewandte Chemie (International ed. in English)
PaperSynthesis of Abeta[1-42] and its derivatives with improved efficiency.
Zarándi, Márta, Soós, Katalin, Fülöp, Lívia, Bozsó, Zsolt, Datki, Zsolt, Tóth, Gábor K, Penke, Botond · 2007 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: Synthesis of Abeta[1-42] and its derivatives with improved efficiency.
PaperAn efficient solid-phase strategy for the construction of chemokines.
McNamara, J F, Lombardo, H, Pillai, S K, Jensen, I, Albericio, F, Kates, S A · 2000 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: An efficient solid-phase strategy for the construction of chemokines.
Authors: McNamara, J F, Lombardo, H, Pillai, S K, Jensen, I, Albericio, F, Kates, S A
Year: 2000
Venue: Journal of peptide science : an official publication of the European Peptide Society
PaperA Novel Method for the Synthesis of Difficult Sequence-Containing Peptides via O-Acyl Isopeptides : The Use of O-N Intramolecular Acyl Migration Reaction
Youhei Sohma, M. Sasaki, Tooru Kimura, Y. Hayashi, Y. Kiso · 2004
Full title: A Novel Method for the Synthesis of Difficult Sequence-Containing Peptides via O-Acyl Isopeptides : The Use of O-N Intramolecular Acyl Migration Reaction
Authors: Youhei Sohma, M. Sasaki, Tooru Kimura, Y. Hayashi, Y. Kiso
Year: 2004
PaperChemistry of alpha-hydroxymethylserine: problems and solutions.
Stasiak, Marcin, Słomczyńska, Urszula, Olma, Aleksandra, Leplawy, Mirosław T · 2008 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: Chemistry of alpha-hydroxymethylserine: problems and solutions.
Authors: Stasiak, Marcin, Słomczyńska, Urszula, Olma, Aleksandra, Leplawy, Mirosław T
Year: 2008
Venue: Journal of peptide science : an official publication of the European Peptide Society
PaperSome 'difficult sequences' made easy. A study of interchain association in solid-phase peptide synthesis.
Hyde, C, Johnson, T, Owen, D, Quibell, M, Sheppard, R C · 1994 · International journal of peptide and protein research
Full title: Some 'difficult sequences' made easy. A study of interchain association in solid-phase peptide synthesis.
Authors: Hyde, C, Johnson, T, Owen, D, Quibell, M, Sheppard, R C
Year: 1994
Venue: International journal of peptide and protein research
PaperEfficient synthesis and characterisation of the amyloid beta peptide, Aβ<sub>1–42</sub>, using a double linker system
Kasim, Johanes K., Kavianinia, Iman, Ng, Jin, Harris, Paul W. R., Birch, Nigel P., Brimble, Margaret A. · 2018 · Organic & Biomolecular Chemistry · DOI
Full title: Efficient synthesis and characterisation of the amyloid beta peptide, Aβ<sub>1–42</sub>, using a double linker system
Authors: Kasim, Johanes K., Kavianinia, Iman, Ng, Jin, Harris, Paul W. R., Birch, Nigel P., Brimble, Margaret A.
Paper'Click peptide': a novel 'O-acyl isopeptide method' for peptide synthesis and chemical biology-oriented synthesis of amyloid beta peptide analogues.
Sohma, Youhei, Taniguchi, Atsuhiko, Yoshiya, Taku, Chiyomori, Yousuke, Fukao, Fukue, Nakamura, Setsuko, Skwarczynski, Mariusz, Okada, Takuma, Ikeda, Keisuke, Hayashi, Yoshio, Kimura, Tooru, Hirota, Shun, Matsuzaki, Katsumi, Kiso, Yoshiaki · 2006 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: 'Click peptide': a novel 'O-acyl isopeptide method' for peptide synthesis and chemical biology-oriented synthesis of amyloid beta peptide analogues.
PaperSelective Peptide Cysteine Manipulation on Demand and Difficult Protein Chemical Synthesis Enabled by Controllable Acidolysis of N,S-Benzylidene Thioacetals.
Wu, Hongxiang, Sun, Zhenquan, Li, Xuechen · 2024 · Angewandte Chemie (International ed. in English) · DOI
Full title: Selective Peptide Cysteine Manipulation on Demand and Difficult Protein Chemical Synthesis Enabled by Controllable Acidolysis of N,S-Benzylidene Thioacetals.
PaperA Versatile "Synthesis Tag" (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins.
Bürgisser, Héloïse, Williams, Elyse T, Jeandin, Aliénor, Lescure, Robin, Premanand, Adhvitha, Wang, Songlin, Hartrampf, Nina · 2024 · Journal of the American Chemical Society · DOI
Full title: A Versatile "Synthesis Tag" (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins.
PaperSyntheses of Difficult Hydrophobic Sequences Using 2-(4-Nitrophenyl)sulfonylethoxycarbonyl(Nsc)-N α-(2-hydroxy- 4-methoxybenzyl)Ala-OH: (Ala)10-Valine, (Ala)15-Valine
H. J. Lee, W. Chweh, Young-Deug Kim, Sangseob Lee, Hack-Joo Kim · 2001 · DOI
Full title: Syntheses of Difficult Hydrophobic Sequences Using 2-(4-Nitrophenyl)sulfonylethoxycarbonyl(Nsc)-N α-(2-hydroxy- 4-methoxybenzyl)Ala-OH: (Ala)10-Valine, (Ala)15-Valine
Authors: H. J. Lee, W. Chweh, Young-Deug Kim, Sangseob Lee, Hack-Joo Kim
PaperHigh‐yield, solid‐phase synthesis of humanin, an Alzheimer's disease associated, novel 24‐mer peptide which contains a difficult sequence
A. Evangelou, C. Zikos, E. Livaniou, G. Evangelatos · 2004 · Journal of Peptide Science · DOI
Full title: High‐yield, solid‐phase synthesis of humanin, an Alzheimer's disease associated, novel 24‐mer peptide which contains a difficult sequence
Authors: A. Evangelou, C. Zikos, E. Livaniou, G. Evangelatos
PaperImproving Internal Peptide Dynamics in the Coarse-Grained MARTINI Model: Toward Large-Scale Simulations of Amyloid- and Elastin-like Peptides.
Seo, Mikyung, Rauscher, Sarah, Pomès, Régis, Tieleman, D Peter · 2012 · Journal of chemical theory and computation · DOI
Full title: Improving Internal Peptide Dynamics in the Coarse-Grained MARTINI Model: Toward Large-Scale Simulations of Amyloid- and Elastin-like Peptides.
Authors: Seo, Mikyung, Rauscher, Sarah, Pomès, Régis, Tieleman, D Peter
PaperSPPS of difficult sequences. A comparison of chemical conditions, synthetic strategies and on-line monitoring.
Dettin, M, Pegoraro, S, Rovero, P, Bicciato, S, Bagno, A, Di Bello, C · 1997 · The journal of peptide research : official journal of the American Peptide Society
Full title: SPPS of difficult sequences. A comparison of chemical conditions, synthetic strategies and on-line monitoring.
Authors: Dettin, M, Pegoraro, S, Rovero, P, Bicciato, S, Bagno, A, Di Bello, C
Year: 1997
Venue: The journal of peptide research : official journal of the American Peptide Society
PaperReverse-phase HPLC of the hydrophobic pulmonary surfactant proteins: detection of a surfactant protein C isoform containing Nepsilon-palmitoyl-lysine.
Gustafsson, M, Curstedt, T, Jörnvall, H, Johansson, J · 1997 · The Biochemical journal · DOI
Full title: Reverse-phase HPLC of the hydrophobic pulmonary surfactant proteins: detection of a surfactant protein C isoform containing Nepsilon-palmitoyl-lysine.
Authors: Gustafsson, M, Curstedt, T, Jörnvall, H, Johansson, J
PaperMultiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations.
Brown, Zachary Z, Mapelli, Claudio, Farasat, Iman, Shoultz, Alycia V, Johnson, Scott A, Orvieto, Federica, Santoprete, Alessia, Bianchi, Elisabetta, McCracken, Amy Bittner, Chen, Kuanchang, Zhu, Xiaohong, Demma, Mark J, Lacey, Brian M, Canada, Keith A, Garbaccio, Robert M, O'Neil, Jennifer, Walji, Abbas · 2020 · The Journal of organic chemistry · DOI
Full title: Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations.
Authors: Brown, Zachary Z, Mapelli, Claudio, Farasat, Iman, Shoultz, Alycia V, Johnson, Scott A, Orvieto, Federica, Santoprete, Alessia, Bianchi, Elisabetta, McCracken, Amy Bittner, Chen, Kuanchang, Zhu, Xiaohong, Demma, Mark J, Lacey, Brian M, Canada, Keith A, Garbaccio, Robert M, O'Neil, Jennifer, Walji, Abbas
PaperA backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation.
Abdel-Aal, Abu-Baker M, Papageorgiou, George, Raz, Richard, Quibell, Martin, Burlina, Fabienne, Offer, John · 2016 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation.
Authors: Abdel-Aal, Abu-Baker M, Papageorgiou, George, Raz, Richard, Quibell, Martin, Burlina, Fabienne, Offer, John
Year: 2016
Venue: Journal of peptide science : an official publication of the European Peptide Society
PaperConverting the Amyloidogenic Islet Amyloid Polypeptide into a Potent Nonaggregating Peptide Ligand by Side Chain-to-Side Chain Macrocyclization.
Babych, Margaryta, Garelja, Michael L, Nguyen, Phuong Trang, Hay, Debbie L, Bourgault, Steve · 2024 · Journal of the American Chemical Society · DOI
Full title: Converting the Amyloidogenic Islet Amyloid Polypeptide into a Potent Nonaggregating Peptide Ligand by Side Chain-to-Side Chain Macrocyclization.
Authors: Babych, Margaryta, Garelja, Michael L, Nguyen, Phuong Trang, Hay, Debbie L, Bourgault, Steve
PaperS-acyl isopeptide method: use of allyl-type protective group for improved preparation of thioester-containing S-acyl isopeptides by Fmoc-based SPPS.
Full title: S-acyl isopeptide method: use of allyl-type protective group for improved preparation of thioester-containing S-acyl isopeptides by Fmoc-based SPPS.
PaperEthyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): a recyclable coupling reagent for racemization-free synthesis of peptide, amide, hydroxamate, and ester.
Dev, Dharm, Palakurthy, Nani Babu, Thalluri, Kishore, Chandra, Jyoti, Mandal, Bhubaneswar · 2014 · The Journal of organic chemistry · DOI
Full title: Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): a recyclable coupling reagent for racemization-free synthesis of peptide, amide, hydroxamate, and ester.
PaperNovel and efficient synthesis of difficult sequence-containing peptides through O-N intramolecular acyl migration reaction of O-acyl isopeptides.
Youhei Sohma, M. Sasaki, Y. Hayashi, Tooru Kimura, Y. Kiso · 2004 · Chemical Communications · DOI
Full title: Novel and efficient synthesis of difficult sequence-containing peptides through O-N intramolecular acyl migration reaction of O-acyl isopeptides.
Authors: Youhei Sohma, M. Sasaki, Y. Hayashi, Tooru Kimura, Y. Kiso
PaperPeptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors
V. Åberg · 2006 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Full title: Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors
Authors: V. Åberg
Year: 2006
Venue: KTH Publication Database DiVA (KTH Royal Institute of Technology)
PaperMicrowave-Assisted Solid-Phase Synthesis of Pseudopeptide Containing Reduced Amide Bond
Mi-Sun Park, Shim Hyeung-Soo, Cho Won-Mi, Lee Keun-Hyeung · 2007 · DOI
Full title: Microwave-Assisted Solid-Phase Synthesis of Pseudopeptide Containing Reduced Amide Bond
Authors: Mi-Sun Park, Shim Hyeung-Soo, Cho Won-Mi, Lee Keun-Hyeung
PaperAmyloid-beta as a "difficult sequence" in solid phase peptide synthesis.
A. Tickler, A. Clippingdale, J. Wade · 2004 · Protein Peptide Letters
Full title: Amyloid-beta as a "difficult sequence" in solid phase peptide synthesis.
Authors: A. Tickler, A. Clippingdale, J. Wade
Year: 2004
Venue: Protein Peptide Letters
PaperNovel amino-Li resin for water-based solid-phase peptide synthesis.
Uth, Christina, Englert, Simon, Avrutina, Olga, Kolmar, Harald, Knauer, Sascha · 2023 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: Novel amino-Li resin for water-based solid-phase peptide synthesis.
PaperRecent progress in the improvement of the coupling efficiency of "difficult sequences" in peptide synthesis.
Han, Xiang, Wang, De-xin · 2007 · Yao xue xue bao = Acta pharmaceutica Sinica
Full title: Recent progress in the improvement of the coupling efficiency of "difficult sequences" in peptide synthesis.
Authors: Han, Xiang, Wang, De-xin
Year: 2007
Venue: Yao xue xue bao = Acta pharmaceutica Sinica
PaperSynthesis of humanin and its derivatives to treat traumatic brain injury in mice
Meridor, David · 2015 · Journal of Molecular and Genetic Medicine
Full title: Synthesis of humanin and its derivatives to treat traumatic brain injury in mice
Authors: Meridor, David
Year: 2015
Venue: Journal of Molecular and Genetic Medicine
Paper"O-Acyl Isopeptide Method" for the Synthesis of Difficult Sequence-Containing Peptides : Application to the Synthesis of Amyloid β Peptide (Aβ) 1-42
Youhei Sohma, Y. Hayashi, Yousuke Chiyomori, Maiko Kimura, M. Sasaki, A. Taniguchi, F. Fukao, Tooru Kimura, Y. Kiso · 2005
Full title: "O-Acyl Isopeptide Method" for the Synthesis of Difficult Sequence-Containing Peptides : Application to the Synthesis of Amyloid β Peptide (Aβ) 1-42
Authors: Youhei Sohma, Y. Hayashi, Yousuke Chiyomori, Maiko Kimura, M. Sasaki, A. Taniguchi, F. Fukao, Tooru Kimura, Y. Kiso
Year: 2005
PaperAmyloidogenic peptides for design of inhibitors of peptide aggregation and as templates for new bionanomaterials
R. Elgersma · 2008 · Utrecht University Repository (Utrecht University)
Full title: Amyloidogenic peptides for design of inhibitors of peptide aggregation and as templates for new bionanomaterials
Authors: R. Elgersma
Year: 2008
Venue: Utrecht University Repository (Utrecht University)
PaperPeptide synthesis on chitin.
Neugebauer, W, Williams, R E, Barbier, J R, Brzezinski, R, Willick, G · 1996 · International journal of peptide and protein research · DOI
Full title: Peptide synthesis on chitin.
Authors: Neugebauer, W, Williams, R E, Barbier, J R, Brzezinski, R, Willick, G
Year: 1996
Venue: International journal of peptide and protein research
PaperSynthesis of ‘difficult’ peptide sequences: application of a depsipeptide technique to the Jung–Redemann 10- and 26-mers and the amyloid peptide Aβ(1–42)
L. A. Carpino, E. Krause, C. D. Sferdean, M. Schumann, H. Fabian, M. Bienert, M. Beyermann · 2004 · DOI
Full title: Synthesis of ‘difficult’ peptide sequences: application of a depsipeptide technique to the Jung–Redemann 10- and 26-mers and the amyloid peptide Aβ(1–42)
Authors: L. A. Carpino, E. Krause, C. D. Sferdean, M. Schumann, H. Fabian, M. Bienert, M. Beyermann
PaperThe ‘O‐acyl isopeptide method’ for the synthesis of difficult sequence‐containing peptides: application to the synthesis of Alzheimer's disease‐related amyloid β peptide (Aβ) 1–42
Youhei Sohma, Y. Hayashi, Maiko Kimura, Yousuke Chiyomori, A. Taniguchi, M. Sasaki, Tooru Kimura, Y. Kiso · 2005 · Journal of Peptide Science · DOI
Full title: The ‘O‐acyl isopeptide method’ for the synthesis of difficult sequence‐containing peptides: application to the synthesis of Alzheimer's disease‐related amyloid β peptide (Aβ) 1–42
Authors: Youhei Sohma, Y. Hayashi, Maiko Kimura, Yousuke Chiyomori, A. Taniguchi, M. Sasaki, Tooru Kimura, Y. Kiso
PaperSemi-synthesis of murine prion protein by native chemical ligation and chemical activation for preparation of polypeptide-α-thioester.
Shi, Lei, Chen, Huai, Zhang, Si-Yu, Chu, Ting-Ting, Zhao, Yu-Fen, Chen, Yong-Xiang, Li, Yan-Mei · 2017 · Journal of peptide science : an official publication of the European Peptide Society · DOI
Full title: Semi-synthesis of murine prion protein by native chemical ligation and chemical activation for preparation of polypeptide-α-thioester.
ThesisDelayed fibril formation of amylin(20-29) by incorporation of alkene dipeptidosulfonamide isosteres obtained by solid phase olefin cross metathesis
Brouwer, Arwin J.; Elgersma, Ronald C.; Jagodzinska, Monika et al. · 2008 · Utrecht University · DOI
Full title: Delayed fibril formation of amylin(20-29) by incorporation of alkene dipeptidosulfonamide isosteres obtained by solid phase olefin cross metathesis
Authors: Brouwer, Arwin J.; Elgersma, Ronald C.; Jagodzinska, Monika; Rijkers, Dirk T.S.; Liskamp, Rob M.J.
ThesisConfigurational and conformational control on formation and oligomerization of 2-C mono-arylated pseudo-proline dipeptide building units by aromatic stacking interactions
Keller, M.; Mutter, M.; Lehmann, C. · 2006 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: Configurational and conformational control on formation and oligomerization of 2-C mono-arylated pseudo-proline dipeptide building units by aromatic stacking interactions
Authors: Keller, M.; Mutter, M.; Lehmann, C.
Year: 2006
Venue: École polytechnique fédérale de Lausanne (EPFL)
ThesisCorrelation between the mobility of spin-labeled peptide chains and resin solvation: An approach to optimize the synthesis of aggregating sequences
Cilli, Eduardo Maffud [UNESP]; Marchetto, Reinaldo [UNESP]; Schreier, S. et al. · 2014 · Universidade Estadual Paulista (UNESP) · DOI
Full title: Correlation between the mobility of spin-labeled peptide chains and resin solvation: An approach to optimize the synthesis of aggregating sequences
Authors: Cilli, Eduardo Maffud [UNESP]; Marchetto, Reinaldo [UNESP]; Schreier, S.; Nakaie, C. R.
ThesisOne-pot Ligation Strategy for Atypical Ubiquitin Chains Synthesis by Using the Trifluoroacetamidomethyl-protected Isopeptide-linked Ub (Tfacm-isoUb) Unit
Si, Yan-Yan; Liang, Lu-Jun; Tang, Shan et al. · 2018 · Hong Kong University of Science and Technology (HKUST) · DOI
Full title: One-pot Ligation Strategy for Atypical Ubiquitin Chains Synthesis by Using the Trifluoroacetamidomethyl-protected Isopeptide-linked Ub (Tfacm-isoUb) Unit
ThesisSolubilizing protecting groups in peptide synthesis. Effect of side‐chain‐attached poly(ethylene glycol) derivatives upon β‐sheet formation of model peptides
MUTTER, M; OPPLIGER, H; ZIER, A · 2006 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: Solubilizing protecting groups in peptide synthesis. Effect of side‐chain‐attached poly(ethylene glycol) derivatives upon β‐sheet formation of model peptides
Authors: MUTTER, M; OPPLIGER, H; ZIER, A
Year: 2006
Venue: École polytechnique fédérale de Lausanne (EPFL)
ThesisLe concept switch-peptides : le potentiel de la migration S,N acylique dans l'induction de l'activité biologique et la rupture de structures secondaires in situ
Murat, Karine · 2006 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: Le concept switch-peptides : le potentiel de la migration S,N acylique dans l'induction de l'activité biologique et la rupture de structures secondaires in situ
Authors: Murat, Karine
Year: 2006
Venue: École polytechnique fédérale de Lausanne (EPFL)
ThesisSynthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors
Bu, Xianzhang; Wu, Xiaoming; Ng, Na Lee Joyce et al. · 2004 · Hong Kong University of Science and Technology (HKUST) · DOI
Full title: Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors
Authors: Bu, Xianzhang; Wu, Xiaoming; Ng, Na Lee Joyce; Mak, Chun Kit; Qin, Chuanguang; Guo, Zhihong
Year: 2004
Venue: Hong Kong University of Science and Technology (HKUST)
Thesis5-aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides
Bughin, Carine; Zhao, Gang; Bienayme, Hugues et al. · 2010 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: 5-aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides
ThesisSteric effects in release of amides from linkers in solid-phase synthesis. Molecular mechanics modeling of key step in peptide and combinatorial chemistry
Norrby, Per-Ola; Jensen, Knud Jørgen · 2006 · Technical University of Denmark (DTU) · DOI
Full title: Steric effects in release of amides from linkers in solid-phase synthesis. Molecular mechanics modeling of key step in peptide and combinatorial chemistry
ThesisSuccessful synthesis of a glial-specific blood-brain barrier shuttle peptide following a fragment condensation approach on a solid-phase resin
Al Musaimi, Othman; Morse, Sophie V; Lombardi, Lucia et al. · 2022 · Imperial College London · DOI
Full title: Successful synthesis of a glial-specific blood-brain barrier shuttle peptide following a fragment condensation approach on a solid-phase resin
Authors: Al Musaimi, Othman; Morse, Sophie V; Lombardi, Lucia; Serban, Simona; Basso, Alessandra; Williams, Daryl R
ThesisSynthesis of multi-module low density lipoprotein receptor class A domains with acid labile cyanopyridiniumylides (CyPY) as aspartic acid masking groups
Neumann, Kevin; Vujinovic, Alex; Kamara, Saidu et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI
Full title: Synthesis of multi-module low density lipoprotein receptor class A domains with acid labile cyanopyridiniumylides (CyPY) as aspartic acid masking groups
ThesisPeptidomimetics for bridging structure and function: Pseudo-prolines (Psi Pro) in peptide synthesis, molecular recognition, and drug design
Tuchscherer, G.; Mutter, M. · 2006 · École polytechnique fédérale de Lausanne (EPFL) · DOI
Full title: Peptidomimetics for bridging structure and function: Pseudo-prolines (Psi Pro) in peptide synthesis, molecular recognition, and drug design
Authors: Tuchscherer, G.; Mutter, M.
Year: 2006
Venue: École polytechnique fédérale de Lausanne (EPFL)
Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
Full title: Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs.
Tailhades, Julien, Takizawa, Hotake, Gait, Michael J, Wellings, Don A, Wade, John D, Aoki, Yoshitsugu, Shabanpoor, Fazel · 2017
Full title: Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs.
Authors: Tailhades, Julien, Takizawa, Hotake, Gait, Michael J, Wellings, Don A, Wade, John D, Aoki, Yoshitsugu, Shabanpoor, Fazel
Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.
Silva, Rúben D M, Franco Machado, João, Gonçalves, Kyle, Lucas, Francisco M, Batista, Salete, Melo, Rita, Morais, Tânia S, Correia, João D G · 2021
Full title: Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.
Authors: Silva, Rúben D M, Franco Machado, João, Gonçalves, Kyle, Lucas, Francisco M, Batista, Salete, Melo, Rita, Morais, Tânia S, Correia, João D G
Studies towards the chemical synthesis of the 18 kDa antigenic protein from Mycobacterium leprae : a thesis presented in partial fulfilment of the requirements for the degree of Ph. D. in Chemistry at Massey University
Love, Stephen George · 2013
Full title: Studies towards the chemical synthesis of the 18 kDa antigenic protein from Mycobacterium leprae : a thesis presented in partial fulfilment of the requirements for the degree of Ph. D. in Chemistry at Massey University
Milde C-Acylierungen zur Synthese von bis- und triselektrophilen Verbindungen sowie deren Umwandlung zu weiteren biologisch relevanten Verbindungen
El-Dahshan, Adeeb · 2009
Full title: Milde C-Acylierungen zur Synthese von bis- und triselektrophilen Verbindungen sowie deren Umwandlung zu weiteren biologisch relevanten Verbindungen
An approach to the semisynthesis of acyl carrier protein : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemistry at Massey University
Prestidge, Ross Leonard · 2012
Full title: An approach to the semisynthesis of acyl carrier protein : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemistry at Massey University
Chemical Studies Toward the Total Synthesis of Lagunamide A Incorporating the Application of Diastereoselective Vinylogous Mukaiyama Aldol Reaction via Kinetic Resolution Methodology
Singh, Simranjeet · 2021
Full title: Chemical Studies Toward the Total Synthesis of Lagunamide A Incorporating the Application of Diastereoselective Vinylogous Mukaiyama Aldol Reaction via Kinetic Resolution Methodology
Solid-phase synthesis of difficult purine-rich PNAs through selective hmb incorporation: Application to the total synthesis of cell penetrating peptide-PNAs
Tailhades, J; Takizawa, H; Gait, MJ et al. · 2020
Full title: Solid-phase synthesis of difficult purine-rich PNAs through selective hmb incorporation: Application to the total synthesis of cell penetrating peptide-PNAs
Authors: Tailhades, J; Takizawa, H; Gait, MJ; Wellings, DA; Wade, JD; Aoki, Y; Shabanpoor, F
Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
Mimna, Richard; Camus, Marie-Stephanie; Schmid, Adrian et al. · 2007
Full title: Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
Design, Synthesis, Characterisation, and Biological Evaluation of Peptides Targeting Infectious Diseases: Host-Directed Therapy against Mycobacterium tuberculosis and Stapled Peptide Fusion-Inhibitors Targeting SARS-CoV-2
Sharma, Anuvratta Priyanka · 2025
Full title: Design, Synthesis, Characterisation, and Biological Evaluation of Peptides Targeting Infectious Diseases: Host-Directed Therapy against Mycobacterium tuberculosis and Stapled Peptide Fusion-Inhibitors Targeting SARS-CoV-2
Fmoc-POAC: [(9-fluorenylmethyloxycarbonyl)-2,2,5,5-tetramethylpyrrolidine-N-oxyl-3-amino-4-carboxylic acid]: A novel protected spin labeled beta-amino acid for peptide and protein chemistry
Tominaga, M.; Barbosa, SR; Poletti, E. F. et al. · 2014
Full title: Fmoc-POAC: [(9-fluorenylmethyloxycarbonyl)-2,2,5,5-tetramethylpyrrolidine-N-oxyl-3-amino-4-carboxylic acid]: A novel protected spin labeled beta-amino acid for peptide and protein chemistry
Authors: Tominaga, M.; Barbosa, SR; Poletti, E. F.; Zukerman-Schpector, J.; Marchetto, Reinaldo [UNESP]; Schreier, S.; Paiva, ACMM; Nakaie, C. R.
Exploring the Synthesis of Peptide Activated Serine Acylating Agents with Enhanced Lactamase Stability: Novel Surrogate β-Lactam Antibiotic-Peptide Hybrids
Gunukula, Venkata · 2025
Full title: Exploring the Synthesis of Peptide Activated Serine Acylating Agents with Enhanced Lactamase Stability: Novel Surrogate β-Lactam Antibiotic-Peptide Hybrids