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Partial Cellular Reprogramming For Anti Aging

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181 papers 602 patents 318 theses

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Paper Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Xueke, Zhou; Hong, Yimei; Zhang, Hao et al. · 2020 · Frontiers in Cell and Developmental Biology · DOI

Full title: Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Authors: Xueke, Zhou; Hong, Yimei; Zhang, Hao; Li, Xin

Year: 2020

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.00364

Paper The interplay of cellular senescence and reprogramming shapes the biological landscape of aging and cancer revealing novel therapeutic avenues.

Ding, Fuan; Yu, Ying; Zhao, Jiangqi et al. · 2025 · Frontiers in cell and developmental biology · DOI

Full title: The interplay of cellular senescence and reprogramming shapes the biological landscape of aging and cancer revealing novel therapeutic avenues.

Authors: Ding, Fuan; Yu, Ying; Zhao, Jiangqi; Wei, Shibo; Zhang, Yan; Han, Jung Ho; Li, Zhuo; Jiang, Hong-Bo; Ryu, Dongryeol; Cho, Minkyoung; Bae, Sung-Jin; Park, Wonyoung; Ha, Ki-Tae; Gao, Bo

Year: 2025

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2025.1593096

Paper Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming

Lai, Xiaowei; Li, Qian; Wu, Fang et al. · 2020 · Frontiers in Cell and Developmental Biology · DOI

Full title: Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming

Authors: Lai, Xiaowei; Li, Qian; Wu, Fang; Lin, Jiechun; Chen, Jiekai; Zheng, Hui; Guo, Lin

Year: 2020

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.00760

Paper Tissue nanotransfection and cellular reprogramming in regenerative medicine and antimicrobial dynamics.

Shakra, Mohammed Youssef · 2025 · Frontiers in bioengineering and biotechnology · DOI

Full title: Tissue nanotransfection and cellular reprogramming in regenerative medicine and antimicrobial dynamics.

Authors: Shakra, Mohammed Youssef

Year: 2025

Venue: Frontiers in bioengineering and biotechnology

DOI: https://doi.org/10.3389/fbioe.2025.1558735

Paper Next-generation direct reprogramming.

Keshri, Riya; Detraux, Damien; Phal, Ashish et al. · 2024 · Frontiers in cell and developmental biology · DOI

Full title: Next-generation direct reprogramming.

Authors: Keshri, Riya; Detraux, Damien; Phal, Ashish; McCurdy, Clara; Jhajharia, Samriddhi; Chan, Tung Ching; Mathieu, Julie; Ruohola-Baker, Hannele

Year: 2024

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2024.1343106

Paper The LIN28/let-7 Pathway in Cancer

Balzeau, Julien; Menezes, Miriam R.; Cao, Siyu et al. · 2017 · Frontiers in Genetics · DOI

Full title: The LIN28/let-7 Pathway in Cancer

Authors: Balzeau, Julien; Menezes, Miriam R.; Cao, Siyu; Hagan, John P.

Year: 2017

Venue: Frontiers in Genetics

DOI: https://doi.org/10.3389/fgene.2017.00031

Paper Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels.

Lee, Yang-Ja; Bernstock, Joshua D; Klimanis, Dace et al. · 2018 · Frontiers in molecular neuroscience · DOI

Full title: Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels.

Authors: Lee, Yang-Ja; Bernstock, Joshua D; Klimanis, Dace; Hallenbeck, John M

Year: 2018

Venue: Frontiers in molecular neuroscience

DOI: https://doi.org/10.3389/fnmol.2018.00022

Paper WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

Chen, Yu-An; Lu, Chen-Yu; Cheng, Tian‐You et al. · 2019 · Frontiers in Oncology · DOI

Full title: WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

Authors: Chen, Yu-An; Lu, Chen-Yu; Cheng, Tian‐You; Pan, Szu‐Hua; Chen, Hsin‐Fu; Chang, Nan‐Shan

Year: 2019

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2019.00060

Paper Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.

Paine, Patrick Treat; Rechsteiner, Cheyenne; Morandini, Francesco et al. · 2023 · Frontiers in aging · DOI

Full title: Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.

Authors: Paine, Patrick Treat; Rechsteiner, Cheyenne; Morandini, Francesco; Desdín-Micó, Gabriela; Mrabti, Calida; Parras, Alberto; Haghani, Amin; Brooke, Robert; Horvath, Steve; Seluanov, Andrei; Gorbunova, Vera; Ocampo, Alejandro

Year: 2023

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2023.1323194

Paper Pancreatic β Cell Mass Death.

Marrif, Husnia I; Al-Sunousi, Salma I · 2016 · Frontiers in pharmacology · DOI

Full title: Pancreatic β Cell Mass Death.

Authors: Marrif, Husnia I; Al-Sunousi, Salma I

Year: 2016

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2016.00083

Paper Cellular Senescence and Ageing: Mechanisms and Interventions

Mylonas, Andreas; O’Loghlen, Ana · 2022 · Frontiers in Aging · DOI

Full title: Cellular Senescence and Ageing: Mechanisms and Interventions

Authors: Mylonas, Andreas; O’Loghlen, Ana

Year: 2022

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2022.866718

Paper Advances in Pluripotent Stem Cells: History, Mechanisms, Technologies, and Applications

Liu, Gele; David, Brian T.; Trawczynski, Matthew et al. · 2019 · Stem Cell Reviews and Reports · DOI

Full title: Advances in Pluripotent Stem Cells: History, Mechanisms, Technologies, and Applications

Authors: Liu, Gele; David, Brian T.; Trawczynski, Matthew; Fessler, Richard G.

Year: 2019

Venue: Stem Cell Reviews and Reports

DOI: https://doi.org/10.1007/s12015-019-09935-x

Paper Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Zhu, Xudong; Chen, Zhiyang; Shen, Weiyan et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Authors: Zhu, Xudong; Chen, Zhiyang; Shen, Weiyan; Huang, Gang; Sedivy, John M.; Wang, Hu; Ju, Zhenyu

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00646-9

Paper - **Journal:** Signal Transduction and Targeted Therapy - **Source:** openalex - **Content Type:** Full text

Ji, Shuaifei; Xiong, Mingchen; Chen, Huating et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: - **Journal:** Signal Transduction and Targeted Therapy - **Source:** openalex - **Content Type:** Full text

Authors: Ji, Shuaifei; Xiong, Mingchen; Chen, Huating; Liu, Yiqiong; Zhou, Laixian; Hong, Yiyue; Wang, Mengyang; Wang, Chunming; Fu, Xiaobing; Sun, Xiaoyan

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01343-5

Paper Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell, Wayne; Goeminne, Ludger J E; Tyshkovskiy, Alexander et al. · 2024 · eLife · DOI

Full title: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Authors: Mitchell, Wayne; Goeminne, Ludger J E; Tyshkovskiy, Alexander; Zhang, Sirui; Chen, Julie Y; Paulo, Joao A; Pierce, Kerry A; Choy, Angelina H; Clish, Clary B; Gygi, Steven P; Gladyshev, Vadim N

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/eLife.90579

Paper In vitro models of cancer stem cells and clinical applications

Franco, Sara Santos; Szczęsna, Karolina; Iliou, Maria S. et al. · 2016 · BMC Cancer · DOI

Full title: In vitro models of cancer stem cells and clinical applications

Authors: Franco, Sara Santos; Szczęsna, Karolina; Iliou, Maria S.; Al‐Qahtani, Mohammed; Mobasheri, Ali; Kobolák, Julianna; Dinnyés, András

Year: 2016

Venue: BMC Cancer

DOI: https://doi.org/10.1186/s12885-016-2774-3

Paper DNA methylation aging clocks: challenges and recommendations

Bell, Christopher G.; Lowe, Robert; Adams, Peter D. et al. · 2019 · Genome biology · DOI

Full title: DNA methylation aging clocks: challenges and recommendations

Authors: Bell, Christopher G.; Lowe, Robert; Adams, Peter D.; Baccarelli, Andrea; Beck, Stephan; Bell, Jordana T.; Christensen, Brock C.; Gladyshev, Vadim N.; Heijmans, Bastiaan T.; Horvath, Steve; Ideker, Trey; Issa, Jean‐Pierre J.; Kelsey, Karl T.; Marioni, Riccardo E.; Reik, Wolf; Relton, Caroline L.; Schalkwyk, Leonard C.; Teschendorff, Andrew E.; Wagner, Wolfgang; Zhang, Kang; Rakyan, Vardhman K.

Year: 2019

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-019-1824-y

Paper Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

Heinrich, Christophe; Blum, Robert; Gascón, Sergio et al. · 2010 · PLoS Biology · DOI

Full title: Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

Authors: Heinrich, Christophe; Blum, Robert; Gascón, Sergio; Masserdotti, Giacomo; Tripathi, Pratibha; Sánchez, Rodrigo; Tiedt, Steffen; Schroeder, Timm; Götz, Magdalena; Berninger, Benedikt

Year: 2010

Venue: PLoS Biology

DOI: https://doi.org/10.1371/journal.pbio.1000373

Paper The dark side of SOX2: cancer - a comprehensive overview

Wuebben, Erin L.; Rizzino, Angie · 2017 · Oncotarget · DOI

Full title: The dark side of SOX2: cancer - a comprehensive overview

Authors: Wuebben, Erin L.; Rizzino, Angie

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.16570

Paper Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man

Sinenko, Sergey; Starkova, T. Yu.; Kuzmin, Andrey A. et al. · 2021 · Frontiers in Cell and Developmental Biology · DOI

Full title: Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man

Authors: Sinenko, Sergey; Starkova, T. Yu.; Kuzmin, Andrey A.; Томилин, А. Н.

Year: 2021

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2021.714370

Paper Graphene based scaffolds effects on stem cells commitment

Bressan, Eriberto; Ferroni, Letizia; Gardin, Chiara et al. · 2014 · Journal of Translational Medicine · DOI

Full title: Graphene based scaffolds effects on stem cells commitment

Authors: Bressan, Eriberto; Ferroni, Letizia; Gardin, Chiara; Sbricoli, Luca; Gobbato, Luca; Ludovichetti, Francesco Saverio; Tocco, Ilaria; Carraro, Amedeo; Piattelli, Adriano; Zavan, Barbara

Year: 2014

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-014-0296-9

Paper Radiation-induced senescence: therapeutic opportunities

Kim, Jae Ho; Brown, Stephen L.; Gordon, Marcia N. · 2023 · Radiation Oncology · DOI

Full title: Radiation-induced senescence: therapeutic opportunities

Authors: Kim, Jae Ho; Brown, Stephen L.; Gordon, Marcia N.

Year: 2023

Venue: Radiation Oncology

DOI: https://doi.org/10.1186/s13014-022-02184-2

Paper GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

Takaku, Motoki; Grimm, Sara A.; Shimbo, Takashi et al. · 2016 · Genome biology · DOI

Full title: GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

Authors: Takaku, Motoki; Grimm, Sara A.; Shimbo, Takashi; Perera, L.; Menafra, Roberta; Stunnenberg, Hendrik G.; Archer, Trevor; Machida, Shinichi; Kurumizaka, Hitoshi; Wade, Paul A.

Year: 2016

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-016-0897-0

Paper Stem cells: past, present, and future

Zakrzewski, Wojciech; Dobrzyński, Maciej; Szymonowicz, Maria et al. · 2019 · Stem Cell Research & Therapy · DOI

Full title: Stem cells: past, present, and future

Authors: Zakrzewski, Wojciech; Dobrzyński, Maciej; Szymonowicz, Maria; Rybak, Zbigniew

Year: 2019

Venue: Stem Cell Research & Therapy

DOI: https://doi.org/10.1186/s13287-019-1165-5

Paper Multi-tissue DNA methylation age predictor in mouse

Stubbs, Thomas M.; Bonder, Marc Jan; Stark, Anne‐Katrien et al. · 2017 · Genome biology · DOI

Full title: Multi-tissue DNA methylation age predictor in mouse

Authors: Stubbs, Thomas M.; Bonder, Marc Jan; Stark, Anne‐Katrien; Krueger, Felix; Meyenn, Ferdinand von; Stegle, Oliver; Reik, Wolf; Reik, Wolf

Year: 2017

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-017-1203-5

Paper DNA methylation in stem cell renewal and multipotency

Berdasco, María; Esteller, Manel · 2011 · Stem Cell Research & Therapy · DOI

Full title: DNA methylation in stem cell renewal and multipotency

Authors: Berdasco, María; Esteller, Manel

Year: 2011

Venue: Stem Cell Research & Therapy

DOI: https://doi.org/10.1186/scrt83

Paper Cellular reprogramming and epigenetic rejuvenation

Simpson, Daniel J.; Olova, Nelly; Chandra, Tamir · 2021 · Clinical Epigenetics · DOI

Full title: Cellular reprogramming and epigenetic rejuvenation

Authors: Simpson, Daniel J.; Olova, Nelly; Chandra, Tamir

Year: 2021

Venue: Clinical Epigenetics

DOI: https://doi.org/10.1186/s13148-021-01158-7

Paper Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines

Mo, Chu-Fan; Wu, Fang-Chun; Tai, Kang‐Yu et al. · 2015 · Stem Cell Research & Therapy · DOI

Full title: Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines

Authors: Mo, Chu-Fan; Wu, Fang-Chun; Tai, Kang‐Yu; Chang, Wei-Chun; Chang, Kai‐Wei; Kuo, Hung‐Chih; Ho, Hong‐Nerng; Chen, Hsin‐Fu; Lin, Shau‐Ping

Year: 2015

Venue: Stem Cell Research & Therapy

DOI: https://doi.org/10.1186/scrt535

Paper Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

Newman, Martin A.; Thomson, J. Michael; Hammond, Scott M. · 2008 · RNA · DOI

Full title: Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

Authors: Newman, Martin A.; Thomson, J. Michael; Hammond, Scott M.

Year: 2008

Venue: RNA

DOI: https://doi.org/10.1261/rna.1155108

Paper DNA Methylation and Histone Modifications Regulate De Novo Shoot Regeneration in Arabidopsis by Modulating WUSCHEL Expression and Auxin Signaling

Li, Wei; Liu, Hui; Cheng, Zhi Juan et al. · 2011 · PLoS Genetics · DOI

Full title: DNA Methylation and Histone Modifications Regulate De Novo Shoot Regeneration in Arabidopsis by Modulating WUSCHEL Expression and Auxin Signaling

Authors: Li, Wei; Liu, Hui; Cheng, Zhi Juan; Su, Ying Hua; Han, Hua; Zhang, Yan; Zhang, Xian Sheng

Year: 2011

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1002243

Paper SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

Lodato, Michael A.; Ng, Christopher; Wamstad, Joseph A. et al. · 2013 · PLoS Genetics · DOI

Full title: SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

Authors: Lodato, Michael A.; Ng, Christopher; Wamstad, Joseph A.; Cheng, Albert W.; Thai, Kevin K.; Fraenkel, Ernest; Jaenisch, Rudolf; Boyer, Laurie A.

Year: 2013

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1003288

Paper Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

Pereira, Carlos‐Filipe; Terranova, Rémi; Ryan, Natalie K. et al. · 2008 · PLoS Genetics · DOI

Full title: Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

Authors: Pereira, Carlos‐Filipe; Terranova, Rémi; Ryan, Natalie K.; Santos, Joana Dos; Morris, Kelly J; Cui, Wei; Merkenschlager, Matthias; Fisher, Amanda G.

Year: 2008

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1000170

Paper Dedifferentiation and Proliferation of Mammalian Cardiomyocytes

Zhang, Yiqiang; Li, Tao‐Sheng; Lee, Shuo-Tsan et al. · 2010 · PLoS ONE · DOI

Full title: Dedifferentiation and Proliferation of Mammalian Cardiomyocytes

Authors: Zhang, Yiqiang; Li, Tao‐Sheng; Lee, Shuo-Tsan; Wawrowsky, Kolja; Cheng, Ke; Galang, Giselle; Malliaras, Konstantinos; Abraham, M. Roselle; Wang, Charles; Marbán, Eduardo

Year: 2010

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0012559

Paper Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells

Marchetto, Maria C.; Yeo, G; Kainohana, Osamu et al. · 2009 · PLoS ONE · DOI

Full title: Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells

Authors: Marchetto, Maria C.; Yeo, G; Kainohana, Osamu; Maršala, Martin; Gage, Fred H.; Muotri, Alysson R.

Year: 2009

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0007076

Paper The PluriNetWork: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications

Som, Anup; Harder, Clemens; Greber, Boris et al. · 2010 · PLoS ONE · DOI

Full title: The PluriNetWork: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications

Authors: Som, Anup; Harder, Clemens; Greber, Boris; Siatkowski, Marcin; Paudel, Yogesh; Warsow, Gregor; Clemens, H.; Schöler, Hans R.; Fuellen, Georg

Year: 2010

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0015165

Paper Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

Carr, Amanda‐Jayne F.; Vugler, Anthony; Hikita, Sherry T. et al. · 2009 · PLoS ONE · DOI

Full title: Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

Authors: Carr, Amanda‐Jayne F.; Vugler, Anthony; Hikita, Sherry T.; Lawrence, Jean M.; Gias, Carlos; Chen, Li; Buchholz, David E.; Ahmado, Ahmad; Semo, Ma’ayan; Smart, Matthew; Hasan, Shazeen Mumtaz; Cruz, Lyndon da; Johnson, Lincoln V.; Clegg, Dennis; Coffey, Peter

Year: 2009

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0008152

Paper Serum Starvation Induced Cell Cycle Synchronization Facilitates Human Somatic Cells Reprogramming

Chen, Mengfei; Huang, Jingjing; Yang, Xuejiao et al. · 2012 · PLoS ONE · DOI

Full title: Serum Starvation Induced Cell Cycle Synchronization Facilitates Human Somatic Cells Reprogramming

Authors: Chen, Mengfei; Huang, Jingjing; Yang, Xuejiao; Liu, Bingqian; Zhang, Weizhong; Huang, Li; Deng, Fei; Ma, Jian; Bai, Yujing; Lu, Rong; Huang, Bing; Gao, Qianying; Zhuo, Yehong; Ge, Jian

Year: 2012

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0028203

Paper Decoding Aging through iPSC Reprogramming: Advances and Challenges

Li, Ruilin; Zou, Yunzeng; Kang, Sheng · 2025 · Aging and Disease · DOI

Full title: Decoding Aging through iPSC Reprogramming: Advances and Challenges

Authors: Li, Ruilin; Zou, Yunzeng; Kang, Sheng

Year: 2025

Venue: Aging and Disease

DOI: https://doi.org/10.14336/ad.2025.0438

Paper Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state.

Kisby, Thomas; de Lázaro, Irene; Stylianou, Maria et al. · 2021 · PloS one · DOI

Full title: Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state.

Authors: Kisby, Thomas; de Lázaro, Irene; Stylianou, Maria; Cossu, Giulio; Kostarelos, Kostas

Year: 2021

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0251054

Paper miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency

Cao, Yang; Guo, Wenting; Tian, Shengya et al. · 2015 · The EMBO Journal · DOI

Full title: miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency

Authors: Cao, Yang; Guo, Wenting; Tian, Shengya; He, Xiaoping; Wang, Xi‐Wen; Liu, Xiaomeng; Gu, Kaili; Ma, Xiaoyu; Huang, De; Hu, Lan; Cai, Yongping; Zhang, Huafeng; Wang, Yangming; Gao, Ping

Year: 2015

Venue: The EMBO Journal

DOI: https://doi.org/10.15252/embj.201490441

Paper Chemically induced reprogramming to reverse cellular aging

Yang, Jae-Hyun; Petty, Christopher A.; Dixon-McDougall, Thomas et al. · 2023 · Aging · DOI

Full title: Chemically induced reprogramming to reverse cellular aging

Authors: Yang, Jae-Hyun; Petty, Christopher A.; Dixon-McDougall, Thomas; Lopez, Maria Vina; Tyshkovskiy, Alexander; Maybury‐Lewis, Sun Y.; Tian, Xiao; Ibrahim, Nabilah; Chen, Zhenyuan; Griffin, Patrick; Arnold, Matthew; Li, Jien; Martinez, Oswaldo A.; Behn, Alexander; Rogers-Hammond, Ryan; Angeli, Suzanne; Gladyshev, Vadim N.; Sinclair, David

Year: 2023

Venue: Aging

DOI: https://doi.org/10.18632/aging.204896

Paper Differentiation and transdifferentiation potentials of cancer stem cells

Huang, Zhengjie; Wu, Tiantian; Liu, Allan Yi et al. · 2015 · Oncotarget · DOI

Full title: Differentiation and transdifferentiation potentials of cancer stem cells

Authors: Huang, Zhengjie; Wu, Tiantian; Liu, Allan Yi; Ouyang, Gaoliang

Year: 2015

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.6098

Paper Direct reprogramming of adult cells: avoiding the pluripotent state.

Kelaini, Sophia; Cochrane, Amy; Margariti, Andriana · 2014 · Stem cells and cloning : advances and applications · DOI

Full title: Direct reprogramming of adult cells: avoiding the pluripotent state.

Authors: Kelaini, Sophia; Cochrane, Amy; Margariti, Andriana

Year: 2014

Venue: Stem cells and cloning : advances and applications

DOI: https://doi.org/10.2147/SCCAA.S38006

Paper Small RNA-mediated regulation of iPS cell generation

Li, Zhonghan; Yang, Chao‐Shun; Nakashima, Katsuhiko et al. · 2011 · The EMBO Journal · DOI

Full title: Small RNA-mediated regulation of iPS cell generation

Authors: Li, Zhonghan; Yang, Chao‐Shun; Nakashima, Katsuhiko; Rana, Tariq M.

Year: 2011

Venue: The EMBO Journal

DOI: https://doi.org/10.1038/emboj.2011.2

Paper Constitutive heterochromatin reorganization during somatic cell reprogramming

Fussner, Eden; Djuric, Ugljesa; Strauss, Mike et al. · 2011 · The EMBO Journal · DOI

Full title: Constitutive heterochromatin reorganization during somatic cell reprogramming

Authors: Fussner, Eden; Djuric, Ugljesa; Strauss, Mike; Hotta, Akitsu; Perez‐Iratxeta, Carolina; Lanner, Fredrik; Dilworth, F. Jeffrey; Ellis, James; Bazett‐Jones, David P.

Year: 2011

Venue: The EMBO Journal

DOI: https://doi.org/10.1038/emboj.2011.96

Paper Human pancreatic beta-like cells converted from fibroblasts

Zhu, Saiyong; Russ, Holger A.; Wang, Xiaojing et al. · 2016 · Nature Communications · DOI

Full title: Human pancreatic beta-like cells converted from fibroblasts

Authors: Zhu, Saiyong; Russ, Holger A.; Wang, Xiaojing; Zhang, Mingliang; Ma, Tianhua; Xu, Tao; Tang, Shibing; Hebrok, Matthias; Ding, Sheng

Year: 2016

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms10080

Paper Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

Almeida, Patricia E. de; Meyer, Everett; Kooreman, Nigel G. et al. · 2014 · Nature Communications · DOI

Full title: Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

Authors: Almeida, Patricia E. de; Meyer, Everett; Kooreman, Nigel G.; Diecke, Sebastian; Dey, Devaveena; Sánchez-Freire, Verónica; Hu, Shijun; Ebert, Antje; Odegaard, Justin I.; Mordwinkin, Nicholas M.; Brouwer, Thomas P.; Lo, David; Montoro, Daniel T.; Longaker, Michael T.; Negrin, Robert S.; Wu, Joseph C.

Year: 2014

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms4903

Paper Direct conversion of human fibroblasts to induced serotonergic neurons

Xu, Zhimin; Jiang, Houbo; Pei, Zhong et al. · 2015 · Molecular Psychiatry · DOI

Full title: Direct conversion of human fibroblasts to induced serotonergic neurons

Authors: Xu, Zhimin; Jiang, Houbo; Pei, Zhong; Yan, Zhen; Chen, Shaochen; Feng, Jun

Year: 2015

Venue: Molecular Psychiatry

DOI: https://doi.org/10.1038/mp.2015.101

Paper Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma

Bagó, Juli R.; Alfonso-Pecchio, Adolfo; Okolie, Onyi et al. · 2016 · Nature Communications · DOI

Full title: Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma

Authors: Bagó, Juli R.; Alfonso-Pecchio, Adolfo; Okolie, Onyi; Dumitru, ‎Raluca; Rinkenbaugh, Amanda L.; Baldwin, Albert S.; Miller, C. Ryan; Magness, Scott T.; Hingtgen, Shawn

Year: 2016

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms10593

Paper Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA

Scarola, Michele; Comisso, Elisa; Pascolo, Rhena et al. · 2015 · Nature Communications · DOI

Full title: Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA

Authors: Scarola, Michele; Comisso, Elisa; Pascolo, Rhena; Chiaradia, Riccardo; Marión, Rosa M.; Schneider, Claudio; Blasco, Marı́a A.; Schoeftner, Stefan; Benetti, Roberta

Year: 2015

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms8631

Paper Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

Chen, Hongwei; Aksoy, Irène; Gonnot, Fabrice et al. · 2015 · Nature Communications · DOI

Full title: Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

Authors: Chen, Hongwei; Aksoy, Irène; Gonnot, Fabrice; Osteil, Pierre; Aubry, Maxime; Hamela, Claire; Rognard, Cloé; Hochard, Arnaud; Voisin, Sophie; Fontaine, Emeline; Mure, Magali; Afanassieff, Marielle; Cleroux, Elouan; Guibert, Sylvain; Chen, Jiaxuan; Vallot, Céline; Acloque, Hervé; Genthon, Clémence; Donnadieu, Cécile; Vos, John De; Sanlaville, Damien; Guérin, Jean François; Weber, Michaël; Stanton, Lawrence W.; Rougeulle, Claire; Pain, Bertrand; Bourillot, Pierre-Yves; Savatier, Pierre

Year: 2015

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms8095

Paper Heterochromatin: an epigenetic point of view in aging

Lee, Jong‐Hyuk; Kim, Edward W.; Croteau, Deborah L. et al. · 2020 · Experimental & Molecular Medicine · DOI

Full title: Heterochromatin: an epigenetic point of view in aging

Authors: Lee, Jong‐Hyuk; Kim, Edward W.; Croteau, Deborah L.; Bohr, Vilhelm A.

Year: 2020

Venue: Experimental & Molecular Medicine

DOI: https://doi.org/10.1038/s12276-020-00497-4

Paper Functional characterization of SOX2 as an anticancer target

Zhang, Shizhen; Xiong, Xiufang; Sun, Yi · 2020 · Signal Transduction and Targeted Therapy · DOI

Full title: Functional characterization of SOX2 as an anticancer target

Authors: Zhang, Shizhen; Xiong, Xiufang; Sun, Yi

Year: 2020

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-020-00242-3

Paper In vivo reprogramming drives Kras-induced cancer development

Shibata, Hirofumi; Komura, Shingo; Yamada, Yosuke et al. · 2018 · Nature Communications · DOI

Full title: In vivo reprogramming drives Kras-induced cancer development

Authors: Shibata, Hirofumi; Komura, Shingo; Yamada, Yosuke; Sankoda, Nao; Tanaka, Akito; Ukai, Tomoyo; Kabata, Mio; Sakurai, Satoko; Kuze, Bunya; Woltjen, Knut; Haga, Hironori; Ito, Yatsuji; Kawaguchi, Yoshiya; Yamamoto, Takuya; Yamada, Yasuhiro

Year: 2018

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-018-04449-5

Paper Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

Sarkar, Tapash Jay; Quarta, Marco; Mukherjee, Shravani et al. · 2020 · Nature Communications · DOI

Full title: Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

Authors: Sarkar, Tapash Jay; Quarta, Marco; Mukherjee, Shravani; Colville, Alex; Paine, Patrick; Doan, Linda; Tran, Christopher M.; Chu, Constance R.; Horvath, Steve; Qi, Lei S.; Bhutani, Nidhi; Rando, Thomas A.; Sebastiano, Vittorio

Year: 2020

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-020-15174-3

Paper The bright side of fibroblasts: molecular signature and regenerative cues in major organs

Gomes, Rita N.; Manuel, Filipa; Nascimento, Diana S. · 2021 · npj Regenerative Medicine · DOI

Full title: The bright side of fibroblasts: molecular signature and regenerative cues in major organs

Authors: Gomes, Rita N.; Manuel, Filipa; Nascimento, Diana S.

Year: 2021

Venue: npj Regenerative Medicine

DOI: https://doi.org/10.1038/s41536-021-00153-z

Paper The long and winding road of reprogramming-induced rejuvenation.

Yücel, Ali Doğa; Gladyshev, Vadim N · 2024 · Nature communications · DOI

Full title: The long and winding road of reprogramming-induced rejuvenation.

Authors: Yücel, Ali Doğa; Gladyshev, Vadim N

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-46020-5

Paper Validation of Common Housekeeping Genes as Reference for qPCR Gene Expression Analysis During iPS Reprogramming Process

Panina, Yulia; Germond, Arno; Masui, Shinji et al. · 2018 · Scientific Reports · DOI

Full title: Validation of Common Housekeeping Genes as Reference for qPCR Gene Expression Analysis During iPS Reprogramming Process

Authors: Panina, Yulia; Germond, Arno; Masui, Shinji; Watanabe, Tomonobu M.

Year: 2018

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-018-26707-8

Paper Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan.

Schoenfeldt, Lucas; Paine, Patrick T; Picó, Sara et al. · 2025 · EMBO molecular medicine · DOI

Full title: Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan.

Authors: Schoenfeldt, Lucas; Paine, Patrick T; Picó, Sara; Kamaludeen M, Nibrasul H; Phelps, Grace B; Mrabti, Calida; Desdín-Micó, Gabriela; Del Carmen Maza, María; Perez, Kevin; Ocampo, Alejandro

Year: 2025

Venue: EMBO molecular medicine

DOI: https://doi.org/10.1038/s44321-025-00265-9

Paper Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

Gauron, Carole; Rampon, Christine; Bouzaffour, Mohamed et al. · 2013 · Scientific Reports · DOI

Full title: Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

Authors: Gauron, Carole; Rampon, Christine; Bouzaffour, Mohamed; Ipendey, Eliane; Teillon, Jérémie; Volovitch, Michel; Vriz, Sophie

Year: 2013

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep02084

Paper Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons

Powell, Curtis; Cornblath, Eli J.; Elsaeidi, Fairouz et al. · 2016 · Scientific Reports · DOI

Full title: Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons

Authors: Powell, Curtis; Cornblath, Eli J.; Elsaeidi, Fairouz; Wan, Jin; Goldman, Daniel

Year: 2016

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep24851

Paper A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice.

Pernomian, Laena; Waigi, Emily W; Nguyen, Vi et al. · 2024 · bioRxiv : the preprint server for biology · DOI

Full title: A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice.

Authors: Pernomian, Laena; Waigi, Emily W; Nguyen, Vi; Mohammed, Ahmed D; da Costa, Tiago J; Fontes, Milene T; Kubinak, Jason L; Aitken, Andrew; Biancardi, Vinicia Campana; Sinclair, David A; McCarthy, Cameron G; Wang, Yunguan; Tan, Wenbin; Wenceslau, Camilla Ferreira

Year: 2024

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2024.05.20.595057

Paper Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

Kim, Jumee; Kim, Somi; Lee, Seungyeon et al. · 2023 · DOI

Full title: Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

Authors: Kim, Jumee; Kim, Somi; Lee, Seungyeon; Jo, Beom‐Ki; Oh, Jiyoung; Kwon, Eun‐Ji; Kim, Keun-Tae; Adpaikar, Anish Ashok; Kim, Eun‐Jung; Jung, Han‐Sung; Hong, Chang Pyo; Kim, Jong; Koo, Bon‐Kyoung; Cha, Hyuk‐Jin; Koo, Bon Kyoung; Cha, Hyuk-Jin

Year: 2023

DOI: https://doi.org/10.1101/2023.02.25.530001

Paper Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.

Paine, Patrick Treat; Rechsteiner, Cheyenne; Morandini, Francesco et al. · 2023 · Frontiers in aging · DOI

Full title: Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.

Year: 2023

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2023.1323194

Paper Signaling Networks Regulating Tooth Organogenesis and Regeneration, and the Specification of Dental Mesenchymal and Epithelial Cell Lineages

Jussila, Maria; Thesleff, Irma · 2012 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: Signaling Networks Regulating Tooth Organogenesis and Regeneration, and the Specification of Dental Mesenchymal and Epithelial Cell Lineages

Authors: Jussila, Maria; Thesleff, Irma

Year: 2012

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a008425

Paper Induced Pluripotency and Epigenetic Reprogramming

Hochedlinger, Konrad; Jaenisch, Rudolf · 2015 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: Induced Pluripotency and Epigenetic Reprogramming

Authors: Hochedlinger, Konrad; Jaenisch, Rudolf

Year: 2015

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a019448

Paper Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response

Lipchina, Inna; Elkabetz, Yechiel; Hafner, Markus et al. · 2011 · Genes & Development · DOI

Full title: Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response

Authors: Lipchina, Inna; Elkabetz, Yechiel; Hafner, Markus; Sheridan, Robert P.; Mihailović, Aleksandra; Tuschl, Thomas; Sander, Chris; Studer, Lorenz; Betel, Doron

Year: 2011

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.17221311

Paper Context-specific α-to-β-cell reprogramming by forced Pdx1 expression

Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F. et al. · 2011 · Genes & Development · DOI

Full title: Context-specific α-to-β-cell reprogramming by forced Pdx1 expression

Authors: Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F.; Herrera, Pedro L.; Wright, Christopher V.E.

Year: 2011

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.16875711

Paper Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

Johnson, Nicole C; Dillard, Miriam E.; Bałuk, Peter et al. · 2008 · Genes & Development · DOI

Full title: Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

Authors: Johnson, Nicole C; Dillard, Miriam E.; Bałuk, Peter; McDonald, Donald M.; Harvey, Natasha L.; Frase, Sharon; Oliver, Guillermo

Year: 2008

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.1727208

Paper Extension of chronological life span in yeast by decreased TOR pathway signaling

Powers, Ryan; Kaeberlein, Matt; Caldwell, Seth D. et al. · 2006 · Genes & Development · DOI

Full title: Extension of chronological life span in yeast by decreased TOR pathway signaling

Authors: Powers, Ryan; Kaeberlein, Matt; Caldwell, Seth D.; Kennedy, Brian K.; Fields, Stanley

Year: 2006

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.1381406

Paper A role for mitotic bookmarking of SOX2 in pluripotency and differentiation

Deluz, Cédric; Friman, Elias T.; Strebinger, Daniel et al. · 2016 · Genes & Development · DOI

Full title: A role for mitotic bookmarking of SOX2 in pluripotency and differentiation

Authors: Deluz, Cédric; Friman, Elias T.; Strebinger, Daniel; Benke, Alexander; Raccaud, Mahé; Callegari, Andrea; Leleu, Marion; Manley, Suliana; Suter, David M.

Year: 2016

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.289256.116

Paper Robust cellular reprogramming occurs spontaneously during liver regeneration

Yanger, Kilangsungla; Zong, Yiwei; Maggs, Lara R. et al. · 2013 · Genes & Development · DOI

Full title: Robust cellular reprogramming occurs spontaneously during liver regeneration

Authors: Yanger, Kilangsungla; Zong, Yiwei; Maggs, Lara R.; Shapira, Suzanne N.; Maddipati, Ravi; Aiello, Nicole M.; Thung, Swan N.; Wells, Rebecca G.; Greenbaum, Linda E.; Stanger, Ben Z.

Year: 2013

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.207803.112

Paper Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis

Hiratani, Ichiro; Ryba, Tyrone; Itoh, Mari et al. · 2009 · Genome Research · DOI

Full title: Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis

Authors: Hiratani, Ichiro; Ryba, Tyrone; Itoh, Mari; Rathjen, Joy; Kulik, Michael; Papp, Bernadett; Fussner, Eden; Bazett‐Jones, David P.; Plath, Kathrin; Dalton, Stephen; Rathjen, Peter D.; Gilbert, David M.

Year: 2009

Venue: Genome Research

DOI: https://doi.org/10.1101/gr.099796.109

Paper Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

MacNeil, Lesley T.; Walhout, Albertha J.M. · 2011 · Genome Research · DOI

Full title: Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

Authors: MacNeil, Lesley T.; Walhout, Albertha J.M.

Year: 2011

Venue: Genome Research

DOI: https://doi.org/10.1101/gr.097378.109

Paper Advances in stem cell therapy for spinal cord injury

Mothe, Andrea J.; Tator, Charles H. · 2012 · Journal of Clinical Investigation · DOI

Full title: Advances in stem cell therapy for spinal cord injury

Authors: Mothe, Andrea J.; Tator, Charles H.

Year: 2012

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci64124

Paper Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

Espejel, Silvia; Roll, Garrett R.; McLaughlin, K. John et al. · 2010 · Journal of Clinical Investigation · DOI

Full title: Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

Authors: Espejel, Silvia; Roll, Garrett R.; McLaughlin, K. John; Lee, Andrew Y.; Zhang, Jenny Y.; Laird, Diana J.; Okita, Keisuke; Yamanaka, Shinya; Willenbring, Holger

Year: 2010

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci43267

Paper Cancer stem cells in the development of liver cancer

Yamashita, Taro; Wang, Xin Wei · 2013 · Journal of Clinical Investigation · DOI

Full title: Cancer stem cells in the development of liver cancer

Authors: Yamashita, Taro; Wang, Xin Wei

Year: 2013

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci66024

Thesis Simulating Direct Conversion of Adult Fibroblasts to Neurons

Eriksson, Joakim · 2017 · Lund University Student Papers · DOI

Full title: Simulating Direct Conversion of Adult Fibroblasts to Neurons

Authors: Eriksson, Joakim

Year: 2017

Venue: Lund University Student Papers

DOI: http://lup.lub.lu.se/student-papers/record/8901569

Thesis Cell reprogramming as a way to produce new functional neurons

Pereira, Maria · 2017 · Lund University (LUP) · DOI

Full title: Cell reprogramming as a way to produce new functional neurons

Authors: Pereira, Maria

Year: 2017

Venue: Lund University (LUP)

DOI: https://lup.lub.lu.se/record/2abf7f80-22b7-403a-bd36-d28450ffddac

Thesis Improving Healthspan through Patient-Derived Artificial Organs from Induced Pluripotent Stem Cells and Two-Photon Polymerization

Espenshade, Connor · 2023 · University of Pennsylvania · DOI

Full title: Improving Healthspan through Patient-Derived Artificial Organs from Induced Pluripotent Stem Cells and Two-Photon Polymerization

Authors: Espenshade, Connor

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/45892

Thesis Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

Humphreys, Tom; Weiser, Keith; Arimoto, Asuka et al. · 2022 · Okinawa Institute of Science and Technology (OIST) · DOI

Full title: Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

Authors: Humphreys, Tom; Weiser, Keith; Arimoto, Asuka; Sasaki, Akane; Uenishi, Gene; Fujimoto, Brent; Kawashima, Takeshi; Taparra, Kekoa; Molnar, Janos; Satoh, Noriyuki; Marikawa, Yusuke; Tagawa, Kuni

Year: 2022

Venue: Okinawa Institute of Science and Technology (OIST)

DOI: https://oist.repo.nii.ac.jp/record/2595/files/fevo-10-769433.pdf

Thesis Modelling conversion of adult skin cells to neurons

Drugge, Viktor · 2018 · Lund University Student Papers · DOI

Full title: Modelling conversion of adult skin cells to neurons

Authors: Drugge, Viktor

Year: 2018

Venue: Lund University Student Papers

DOI: http://lup.lub.lu.se/student-papers/record/8940614

Thesis CDKN2B Upregulation Prevents Teratoma Formation in Multipotent Fibromodulin-Reprogrammed Cells

Zheng, Zhong; Li, Chenshuang; Ha, Pin et al. · 2023 · University of Pennsylvania · DOI

Full title: CDKN2B Upregulation Prevents Teratoma Formation in Multipotent Fibromodulin-Reprogrammed Cells

Authors: Zheng, Zhong; Li, Chenshuang; Ha, Pin; Chang, Grace X.; Yang, Pu; Zhang, Xinli; Kim, Jong Kil; Jiang, Wenlu; Pang, Xiaoxiao; Berthiaume, Emily A.; Mills, Zane; Haveles, Christos S.; Chen, Eric; Tine, Kang; Soo, Chia

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/9234

Thesis Direct Reprogramming—The Future of Cardiac Regeneration?

Doppler, Stefanie; Deutsch, Marcus-André; Lange, Rüdiger et al. · 2015 · Technical University of Munich (TUM) · DOI

Full title: Direct Reprogramming—The Future of Cardiac Regeneration?

Authors: Doppler, Stefanie;Deutsch, Marcus-André;Lange, Rüdiger;Krane, Markus

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1323689

Thesis Acquisition and maintenance of pluripotency are influenced by fibroblast growth factor, leukemia inhibitory factor, and 2i in bovine-induced pluripotent stem cells

Botigelli, Ramon Cesar [UNESP]; Pieri, Naira Carolina Godoy; Bessi, Brendon William et al. · 2023 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Acquisition and maintenance of pluripotency are influenced by fibroblast growth factor, leukemia inhibitory factor, and 2i in bovine-induced pluripotent stem cells

Authors: Botigelli, Ramon Cesar [UNESP]; Pieri, Naira Carolina Godoy; Bessi, Brendon William; Machado, Lucas Simões; Bridi, Alessandra; de Souza, Aline Fernanda; Recchia, Kaiana; Neto, Paulo Fantinato; Ross, Pablo Juan; Bressan, Fabiana Fernandes; Nogueira, Marcelo Fábio Gouveia [UNESP]

Year: 2023

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.3389/fcell.2022.938709

Thesis Células tronco pluripotentes induzidas: importância e estado da arte da pesquisa brasileira

Santos Junior, Roque Silva dos [UNESP] · 2023 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Células tronco pluripotentes induzidas: importância e estado da arte da pesquisa brasileira

Authors: Santos Junior, Roque Silva dos [UNESP]

Year: 2023

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/239166

Thesis Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks

Benevento, Marco; Tonge, Peter D; Puri, Mira C et al. · 2014 · Utrecht University · DOI

Full title: Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks

Authors: Benevento, Marco; Tonge, Peter D; Puri, Mira C; Hussein, Samer M I; Cloonan, Nicole; Wood, David L; Grimmond, Sean M; Nagy, Andras; Munoz, Javier; Heck, Albert J R

Year: 2014

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/304285

Thesis Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53

Dirac, A.M.G.; Bernards, R.A. · 2003 · Utrecht University · DOI

Full title: Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53

Authors: Dirac, A.M.G.; Bernards, R.A.

Year: 2003

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/17754

Thesis Small RNA changes en route to distinct cellular states of induced pluripotency

Clancy, Jennifer L; Patel, Hardip R; Hussein, Samer M I et al. · 2014 · Utrecht University · DOI

Full title: Small RNA changes en route to distinct cellular states of induced pluripotency

Authors: Clancy, Jennifer L; Patel, Hardip R; Hussein, Samer M I; Tonge, Peter D; Cloonan, Nicole; Corso, Andrew J; Li, Mira; Lee, Dong-Sung; Shin, Jong-Yeon; Wong, Justin J L; Bailey, Charles G; Benevento, Marco; Munoz, Javier; Chuah, Aaron; Wood, David; Rasko, John E J; Heck, Albert J R; Grimmond, Sean M; Rogers, Ian M; Seo, Jeong-Sun; Wells, Christine A; Puri, Mira C; Nagy, Andras; Preiss, Thomas

Year: 2014

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/304286

Thesis Resilience to aging in the regeneration-capable flatworm Macrostomum lignano

Mouton, Stijn; Grudniewska, Magda; Glazenburg, Lisa et al. · 2018 · Utrecht University · DOI

Full title: Resilience to aging in the regeneration-capable flatworm Macrostomum lignano

Authors: Mouton, Stijn; Grudniewska, Magda; Glazenburg, Lisa; Guryev, Victor; Berezikov, Eugene

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/369059

Thesis MicroRNA Roles in Cell Reprogramming Mechanisms

Pascale, Emilia; Caiazza, Carmen; Paladino, Martina et al. · 2022 · Utrecht University · DOI

Full title: MicroRNA Roles in Cell Reprogramming Mechanisms

Authors: Pascale, Emilia; Caiazza, Carmen; Paladino, Martina; Parisi, Silvia; Passaro, Fabiana; Caiazzo, Massimiliano

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/422225

Thesis Hepatocyte-like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers

Chen, Chen; Pla-Palacín, Iris; Baptista, Pedro M. et al. · 2018 · Utrecht University · DOI

Full title: Hepatocyte-like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers

Authors: Chen, Chen; Pla-Palacín, Iris; Baptista, Pedro M.; Shang, Peng; Oosterhoff, Loes A.; van Wolferen, Monique E.; Penning, Louis C.; Geijsen, Niels; Spee, Bart

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/377295

Thesis Direct Cell Conversion of Somatic Cells into Dopamine Neurons: Achievements and Perspectives

Aversano, Simona; Palladino, Renata; Caiazzo, Massimiliano · 2022 · Utrecht University · DOI

Full title: Direct Cell Conversion of Somatic Cells into Dopamine Neurons: Achievements and Perspectives

Authors: Aversano, Simona; Palladino, Renata; Caiazzo, Massimiliano

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/424164

Thesis Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

Aversano, Simona; Caiazza, Carmen; Caiazzo, Massimiliano · 2022 · Utrecht University · DOI

Full title: Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

Authors: Aversano, Simona; Caiazza, Carmen; Caiazzo, Massimiliano

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/425930

Thesis Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species

Fang, Juntao; Yang, Qiangbing; Maas, Renée G C et al. · 2024 · Utrecht University · DOI

Full title: Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species

Authors: Fang, Juntao; Yang, Qiangbing; Maas, Renée G C; Buono, Michele; Meijlink, Bram; Lotgerink Bruinenberg, Dyonne; Benavente, Ernest Diez; Mokry, Michal; van Mil, Alain; Qian, Li; Goumans, Marie-José; Schiffelers, Raymond; Lei, Zhiyong; Sluijter, Joost P G

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451082

Thesis Molecular Control of Induced Pluripotency

Theunissen, Thorold W.; Jaenisch, Rudolf · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Molecular Control of Induced Pluripotency

Authors: Theunissen, Thorold W.; Jaenisch, Rudolf

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/104363

Thesis RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming

Toh, Cheng-Xu Delon; Chan, Jun-Wei; Chong, Zheng-Shan et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming

Authors: Toh, Cheng-Xu Delon; Chan, Jun-Wei; Chong, Zheng-Shan; Wang, Hao Fei; Guo, Hong Chao; Satapathy, Sandeep; Ma, Dongrui; Goh, Germaine Yen Lin; Khattar, Ekta; Tergaonkar, Vinay; Chang, Young-Tae; Collins, James J.; Daley, George Q.; Wee, Keng Boon; Farran, Chadi A. EL; Li, Hu; Lim, Yoon-Pin; Bard, Frederic A.; Loh, Yuin-Han; Collins, James J.; Yang, Lin

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/103550

Thesis The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

Buganim, Yosef; Markoulaki, Styliani; van Wietmarschen, Niek et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

Authors: Buganim, Yosef; Markoulaki, Styliani; van Wietmarschen, Niek; Wu, Tao; Ganz, Kibibi; Akhtar-Zaidi, Batool; He, Yupeng; Abraham, Brian J.; Porubsky, David; Kulenkampff, Elisabeth; Shi, Linyu; Gao, Qing; Sarkar, Sovan; Cohen, Malkiel; Goldmann, Johanna; Nery, Joseph R.; Schultz, Matthew D.; Ecker, Joseph R.; Xiao, Andrew; Lansdorp, Peter M.; Hoke, Heather Ashley; Jaenisch, Rudolf; Faddah, Dina A.; Young, Richard A.

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/109508

Thesis Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes

Iacovides, Demetris; Rizki, Gizem; Lapathitis, Georgios et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes

Authors: Iacovides, Demetris; Rizki, Gizem; Lapathitis, Georgios; Strati, Katerina

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/103916

Thesis ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors

Skamagki, Maria; Correia, Cristina; Yeung, Percy et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors

Authors: Skamagki, Maria; Correia, Cristina; Yeung, Percy; Baslan, Timour; Beck, Samuel; Zhang, Cheng; Ross, Christian A.; Dang, Lam; Liu, Zhong; Giunta, Simona; Chang, Tzu-Pei; Wang, Joye; Ananthanarayanan, Aparna; Bohndorf, Martina; Bosbach, Benedikt; Adjaye, James; Funabiki, Hironori; Kim, Jonghwan; Lowe, Scott; Lu, Chi-Wei; Li, Hu; Zhao, Rui; Kim, Kitai; Collins, James J.

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/117588

Thesis A dynamical model for the low efficiency of induced pluripotent stem cell reprogramming

Abdallah, Hussein M.; Qian, Yili; Del Vecchio, Domitilla · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A dynamical model for the low efficiency of induced pluripotent stem cell reprogramming

Authors: Abdallah, Hussein M.; Qian, Yili; Del Vecchio, Domitilla

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/107844

Thesis Editing DNA Methylation in the Mammalian Genome

Liu, X. Shawn; Wu, Hao; Ji, Xiong et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Editing DNA Methylation in the Mammalian Genome

Authors: Liu, X. Shawn; Wu, Hao; Ji, Xiong; Stelzer, Yonatan; Czauderna, Szymon; Shu, Jian; Dadon, Daniel Benjamin; Jaenisch, Rudolf; Wu, Xuebing, Ph. D. Massachusetts Institute of Technology; Young, Richard A.

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116619

Thesis Engineering cell fate: Applying synthetic biology to cellular reprogramming

Wang, Nathan B; Beitz, Adam M; Galloway, Katie · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Engineering cell fate: Applying synthetic biology to cellular reprogramming

Authors: Wang, Nathan B; Beitz, Adam M; Galloway, Katie

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133290.2

Thesis Transcriptomic reprogramming for neuronal age reversal

Plesa, Alexandru M.; Shadpour, Michael; Boyden, Ed et al. · 2023 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Transcriptomic reprogramming for neuronal age reversal

Authors: Plesa, Alexandru M.; Shadpour, Michael; Boyden, Ed; Church, George M.

Year: 2023

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/150336

Thesis Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

Cacchiarelli, Davide; Trapnell, Cole; Ziller, Michael J. et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

Authors: Cacchiarelli, Davide; Trapnell, Cole; Ziller, Michael J.; Soumillon, Magali; Cesana, Marcella; Karnik, Rahul; Donaghey, Julie; Smith, Zachary D.; Ratanasirintrawoot, Sutheera; Zhang, Xiaolan; Ho Sui, Shannan J.; Wu, Zhaoting; Akopian, Veronika; Gifford, Casey A.; Doench, John; Rinn, John L.; Daley, George Q.; Meissner, Alexander; Mikkelsen, Tarjei S.; Lander, Eric Steven

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/106526

Thesis A model for genetic and epigenetic regulatory networks identifies rare for transcription factor induced pluripotency

Artyomov, Maxim N.; Meissner, Alexander; Chakraborty, Arup K. · 2010 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A model for genetic and epigenetic regulatory networks identifies rare for transcription factor induced pluripotency

Authors: Artyomov, Maxim N.; Meissner, Alexander; Chakraborty, Arup K.

Year: 2010

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/57580

Thesis Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Xing, QR; El Farran, CA; Gautam, P et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Authors: Xing, QR; El Farran, CA; Gautam, P; Chuah, YS; Warrier, T; Toh, CXD; Kang, NY; Sugii, S; Chang, YT; Xu, J; Collins, JJ; Daley, GQ; Li, H; Zhang, LF; Loh, YH

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133493

Thesis Reprogramming human somatic cells to pluripotency using RNA

Angel, Matthew (Matthew M.) · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Reprogramming human somatic cells to pluripotency using RNA

Authors: Angel, Matthew (Matthew M.)

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/70786

Thesis Pan-Src Family Kinase Inhibitors Replace Sox2 during the Direct Reprogramming of Somatic Cells

Staerk, Judith; Lyssiotis, Costas A.; Medeiro, Lea A. et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Pan-Src Family Kinase Inhibitors Replace Sox2 during the Direct Reprogramming of Somatic Cells

Authors: Staerk, Judith; Lyssiotis, Costas A.; Medeiro, Lea A.; Bollong, Michael; Foreman, Ruth K.; Zhu, Shoutian; Garcia, Michael; Gao, Qing; Bouchez, Laure C.; Lairson, Luke L.; Charette, Bradley D.; Supekova, Lubica; Janes, Jeffrey; Brinker, Achim; Cho, Charles Y.; Jaenisch, Rudolf; Schultz, Peter G.

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/73479

Thesis Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Kim, Jongpil; Lengner, Christopher J.; Kirak, Oktay et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Authors: Kim, Jongpil; Lengner, Christopher J.; Kirak, Oktay; Hanna, Jacob; Cassady, John P.; Lodato, Michael Anthony; Wu, Su; Faddah, Dina A.; Steine, Eveline J.; Gao, Qing; Fu, DongDong; Dawlaty, Meelad M.; Jaenisch, Rudolf

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/73480

Thesis Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Hanna, Jacob; Markoulaki, Styliani; Mathur, Divya et al. · 2010 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Authors: Hanna, Jacob; Markoulaki, Styliani; Mathur, Divya; Staerk, Judith; Foreman, Ruth K.; Jaenisch, Rudolf; Schultz, Peter G.; Cho, Charles Y.; Brinker, Achim; Kunick, Conrad; Bollong, Michael; Bouchez, Laure C.; Charette, Bradley D.; Lairson, Luke L.; Garcia, Michael; Lyssiotis, Costas A.

Year: 2010

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/52555

Thesis Chromatin-modifying enzymes as modulators of reprogramming

Onder, Tamer T.; Kara, Nergis; Cherry, Anne et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Chromatin-modifying enzymes as modulators of reprogramming

Authors: Onder, Tamer T.; Kara, Nergis; Cherry, Anne; Sinha, Amit U.; Zhu, Nan; Bernt, Kathrin M.; Cahan, Patrick; Marcarci, B. Ogan; Unternaehrer, Juli; Armstrong, Scott A.; Daley, George Q.; Gupta, Piyush; Lander, Eric Steven

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/84482

Thesis Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm

Jaenisch, Rudolf · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm

Authors: Jaenisch, Rudolf

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/84640

Thesis Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Buganim, Yosef; Faddah, Dina A.; Itskovich, Elena et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Authors: Buganim, Yosef; Faddah, Dina A.; Itskovich, Elena; Markoulaki, Styliani; Ganz, Kibibi; van Oudenaarden, Alexander; Jaenisch, Rudolf; Klemm, Sandy Lee; van Oudenaarden, Alexander; Cheng, Albert Wu

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/91944

Thesis Direct cell reprogramming is a stochastic process amenable to acceleration

Jaenisch, Rudolf; Lengner, Christopher J.; van Oudenaarden, Alexander et al. · 2010 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Direct cell reprogramming is a stochastic process amenable to acceleration

Authors: Jaenisch, Rudolf; Lengner, Christopher J.; van Oudenaarden, Alexander; Van Zon, Jeroen Sebastiaan; Pando, Bernardo Fabian; Saha, Krishanu; Hanna, Jacob; Creyghton, Menno P.

Year: 2010

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/58480

Thesis A stochastic model dissects cell states in biological transition processes

Armond, Jonathan W.; Saha, Krishanu; Rana, Anas A. et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A stochastic model dissects cell states in biological transition processes

Authors: Armond, Jonathan W.; Saha, Krishanu; Rana, Anas A.; Oates, Chris J.; Jaenisch, Rudolf; Nicodemi, Mario; Mukherjee, Sach

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/88212

Thesis Epigenetic memory in induced pluripotent stem cells

Kim, K.; Doi, A.; Wen, B. et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Epigenetic memory in induced pluripotent stem cells

Authors: Kim, K.; Doi, A.; Wen, B.; Ng, K.; Zhao, R.; Cahan, Patrick; Kim, J.; Aryee, M. J.; Ji, H.; Ehrlich, L. I. R.; Yabuuchi, A.; Takeuchi, A.; Cunniff, K. C.; Hongguang, H.; Mckinney-Freeman, S.; Naveiras, O.; Yoon, T. J.; Irizarry, Rafael A.; Jung, N.; Seita, J.; Hanna, Jacob; Murakami, P.; Jaenisch, Rudolf; Weissleder, R.; Orkin, Stuart H.

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/73941

Thesis Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Soldner, Frank; Hockemeyer, Dirk; Beard, Caroline et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Authors: Soldner, Frank; Hockemeyer, Dirk; Beard, Caroline; Gao, Qing; Bell, George W.; Cook, Elizabeth G.; Hargus, Gunnar; Blak, Alexandra; Cooper, Oliver; Mitalipova, Maisam; Isacson, Ole; Jaenisch, Rudolf

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96268

Thesis The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Unternaehrer, Juli J.; Zhao, Rui; Kim, Kitai et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Authors: Unternaehrer, Juli J.; Zhao, Rui; Kim, Kitai; Cesana, Marcella; Powers, John T.; Ratanasirintrawoot, Sutheera; Onder, Tamer T.; Shibue, Tsukasa; Weinberg, Robert A.; Daley, George Q.; Weinberg, Robert A

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96337

Thesis Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues

Hanna, Jacob; Saha, Krishanu; Jaenisch, Rudolf · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues

Authors: Hanna, Jacob; Saha, Krishanu; Jaenisch, Rudolf

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96107

Thesis Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Cassady, John P.; D’Alessio, Ana C.; Sarkar, Sovan et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Authors: Cassady, John P.; D’Alessio, Ana C.; Sarkar, Sovan; Fan, Zi Peng; Ganz, Kibibi; Roessler, Reinhard; Sur, Mriganka; Young, Richard A.; Jaenisch, Rudolf; Dani, Vardhan; Young, Richard A.

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96277

Thesis Modeling Stem Cell Induction Processes

Gracio, Filipe; Cabral, Joaquim M. S.; Tidor, Bruce · 2013 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Modeling Stem Cell Induction Processes

Authors: Gracio, Filipe; Cabral, Joaquim M. S.; Tidor, Bruce

Year: 2013

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/79416

Thesis Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

Carey, Bryce W.; Markoulaki, Styliani; Hanna, Jacob et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

Authors: Carey, Bryce W.; Markoulaki, Styliani; Hanna, Jacob; Faddah, Dina A.; Buganim, Yosef; Kim, Jongpil; Ganz, Kibibi; Steine, Eveline J.; Cassady, John P.; Creyghton, Menno P.; Welstead, G. Grant; Gao, Qing; Jaenisch, Rudolf

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/95810

Thesis Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Ring, Karen Lee · 2012 · University of California, San Francisco (UCSF) · DOI

Full title: Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Authors: Ring, Karen Lee

Year: 2012

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/359616z5

Thesis Reprogramming scleroderma-specific and normal fibroblast gene subsets using single versus multiple transcription factors

Van Buren, Tyler Martin · 2010 · University of California, San Diego (UCSD) · DOI

Full title: Reprogramming scleroderma-specific and normal fibroblast gene subsets using single versus multiple transcription factors

Authors: Van Buren, Tyler Martin

Year: 2010

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0r08856j

Thesis Multiple Transcription Factor Perturbations Rejuvenate Aged Human Skin Fibroblasts with a Conserved Transcriptional Signature

Sengstack, Janine · 2023 · University of California, San Francisco (UCSF) · DOI

Full title: Multiple Transcription Factor Perturbations Rejuvenate Aged Human Skin Fibroblasts with a Conserved Transcriptional Signature

Authors: Sengstack, Janine

Year: 2023

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/6s9064q0

Thesis Designing and characterizing artificial transcription factors targeting critical embryonic stem cell self- renewal and pluripotency genes in somatic cells

Yang, Steven · 2009 · University of California, San Diego (UCSD) · DOI

Full title: Designing and characterizing artificial transcription factors targeting critical embryonic stem cell self- renewal and pluripotency genes in somatic cells

Authors: Yang, Steven

Year: 2009

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/3tk6c44c

Thesis Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine

Yeola, Avani; Subramanian, Shruthi; Oliver, Rema A et al. · 2021 · UNSW Sydney · DOI

Full title: Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine

Authors: Yeola, Avani; Subramanian, Shruthi; Oliver, Rema A ; https://orcid.org/0000-0002-2381-7326; Lucas, Christine A; Thoms, Julie AI ; https://orcid.org/0000-0002-4876-7230; Yan, Feng; Olivier, Jake ; https://orcid.org/0000-0002-3144-4507; Chacon, Diego; Tursky, Melinda L ; https://orcid.org/0000-0001-7777-4491; Hung, Tzongtyng ; https://orcid.org/0000-0002-2904-2664; Power, Carl ; https://orcid.org/0000-0003-2357-2987; Hardy, Philip; D., David; McCarroll, Joshua ; https://orcid.org/0000-0001-8807-3623; Kavallaris, Maria ; https://orcid.org/0000-0003-2309-898X; Hesson, Luke B; Beck, Dominik; Curtis, David J; Wong, Jason WH ; https://orcid.org/0000-0003-2953-7728; Hardeman, Edna C ; https://orcid.org/0000-0003-1649-7712; Walsh, William R ; https://orcid.org/0000-0002-5023-6148; Mobbs, Ralph ; https://orcid.org/0000-0001-6542-6836; Chandrakanthan, Vashe; Pimanda, John E ; https://orcid.org/0000-0002-0509-8962; Kilian, Kristopher ; https://orcid.org/0000-0002-8963-9796; Potas, Jason ; https://orcid.org/0000-0002-1973-8211; Ma, David; Subramanian, Shruthi; Srivastava, Pallavi; Chacon Fajardo, Diego ; https://orcid.org/0000-0003-3729-1385

Year: 2021

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_75132

Thesis A Combined Epigenetic and Non-Genetic Approach for Reprogramming Human Somatic Cells

Han, J; Sachdev, P; https://orcid.org/0000-0002-9595-3220 et al. · 2010 · UNSW Sydney · DOI

Full title: A Combined Epigenetic and Non-Genetic Approach for Reprogramming Human Somatic Cells

Authors: Han, J; Sachdev, P ; https://orcid.org/0000-0002-9595-3220; Sidhu, K

Year: 2010

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_38308

Thesis H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

Hörmanseder, E; Simeone, A; Allen, GE et al. · 2017 · University of Cambridge · DOI

Full title: H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

Authors: Hörmanseder, E; Simeone, A; Allen, GE; Bradshaw, CR; Figlmüller, M; Gurdon, J; Jullien, J

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/264440

Thesis Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.

Miyamoto, Kei; Nguyen, Khoi T; Allen, George E et al. · 2018 · University of Cambridge · DOI

Full title: Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.

Authors: Miyamoto, Kei; Nguyen, Khoi T; Allen, George E; Jullien, Jerome; Kumar, Dinesh; Otani, Tomoki; Bradshaw, Charles R; Livesey, Frederick J; Kellis, Manolis; Gurdon, John B

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/283552

Thesis Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming.

Yang, Jian; Rajan, Sandeep S; Friedrich, Mathias J et al. · 2019 · University of Cambridge · DOI

Full title: Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming.

Authors: Yang, Jian; Rajan, Sandeep S; Friedrich, Mathias J; Lan, Guocheng; Zou, Xiangang; Ponstingl, Hannes; Garyfallos, Dimitrios A; Liu, Pentao; Bradley, Allan; Metzakopian, Emmanouil

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/289965

Thesis REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

Drouin-Ouellet, Janelle; Lau, Shong; Brattås, Per Ludvik et al. · 2017 · University of Cambridge · DOI

Full title: REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

Authors: Drouin-Ouellet, Janelle; Lau, Shong; Brattås, Per Ludvik; Rylander Ottosson, Daniella; Pircs, Karolina; Grassi, Daniela A; Collins, Lucy M; Vuono, Romina; Andersson Sjöland, Annika; Westergren-Thorsson, Gunilla; Graff, Caroline; Minthon, Lennart; Toresson, Håkan; Barker, Roger A; Jakobsson, Johan; Parmar, Malin

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/269725

Thesis Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

Stricker, SH; Feber, A; Engström, PG et al. · 2019 · University of Cambridge · DOI

Full title: Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

Authors: Stricker, SH; Feber, A; Engström, PG; Carén, H; Kurian, KM; Takashima, Y; Watts, C; Way, M; Dirks, P; Bertone, P; Smith, A; Beck, S; Pollard, SM

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/295900

Thesis Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Liou, Roxanne Hsiang-Chi; Edwards, Thomas L.; Martin, Keith R. et al. · 2020 · University of Cambridge · DOI

Full title: Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Authors: Liou, Roxanne Hsiang-Chi; Edwards, Thomas L.; Martin, Keith R.; Wong, Raymond Ching-Bong

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/306895

Thesis Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges.

Gam, Rihab; Sung, Minkyung; Prasad Pandurangan, Arun · 2019 · University of Cambridge · DOI

Full title: Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges.

Authors: Gam, Rihab; Sung, Minkyung; Prasad Pandurangan, Arun

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/297537

Thesis Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.

Martin-Herranz, Daniel E; Aref-Eshghi, Erfan; Bonder, Marc Jan et al. · 2020 · University of Cambridge · DOI

Full title: Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.

Authors: Martin-Herranz, Daniel E; Aref-Eshghi, Erfan; Bonder, Marc Jan; Stubbs, Thomas M; Choufani, Sanaa; Weksberg, Rosanna; Stegle, Oliver; Sadikovic, Bekim; Reik, Wolf; Thornton, Janet M

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/309125

Thesis Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle et al. · 2021 · University of Cambridge · DOI

Full title: Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Authors: Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle; Stoker, Tom; Barker, Roger; Rylander Ottosson, Daniella

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/331334

Thesis Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Gill, Diljeet; Parry, Aled; Santos, Fátima et al. · 2022 · University of Cambridge · DOI

Full title: Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Authors: Gill, Diljeet; Parry, Aled; Santos, Fátima; Okkenhaug, Hanneke; Todd, Christopher D; Hernando-Herraez, Irene; Stubbs, Thomas M; Milagre, Inês; Reik, Wolf

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/336968

Thesis Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.

Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc et al. · 2022 · University of Cambridge · DOI

Full title: Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.

Authors: Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc; Urdinguio, Rocio G; Berenguer-Llergo, Antonio; Aguilera, Mònica; Durand, Sylvere; Aprahamian, Fanny; Nirmalathasan, Nitharsshini; Abad, Maria; Martin-Herranz, Daniel E; Stephan-Otto Attolini, Camille; Prats, Neus; Kroemer, Guido; Fraga, Mario F; Reik, Wolf; Serrano, Manuel

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/334599

Thesis Tumor suppressors inhibit reprogramming of African spiny mouse ( Acomys) fibroblasts to induced pluripotent stem cells.

Sandoval, Aaron Gabriel W; Maden, Malcolm; Bates, Lawrence E et al. · 2022 · University of Cambridge · DOI

Full title: Tumor suppressors inhibit reprogramming of African spiny mouse ( Acomys) fibroblasts to induced pluripotent stem cells.

Authors: Sandoval, Aaron Gabriel W; Maden, Malcolm; Bates, Lawrence E; Silva, Jose CR

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/341708

Thesis Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Wen, Ming-Hsuan; Triana, Hector Barbosa; Butler, Richard et al. · 2023 · University of Cambridge · DOI

Full title: Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Authors: Wen, Ming-Hsuan; Triana, Hector Barbosa; Butler, Richard; Hu, Hsiang-Wei; Dai, Yang-Hong; Lawrence, Nicola; Hong, Jun-Jie; Garrett, Nigel; Jones-Green, Rue; Rawlins, Emma L; Dong, Ziqi; Koziol, Magdalena J; Gurdon, JB

Year: 2023

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/361522

Thesis Ageing versus developmental silencing: Answers from the epigenome.

Sadler, Kirsten C; Storer, Mekayla A; Bayin, N Sumru · 2025 · University of Cambridge · DOI

Full title: Ageing versus developmental silencing: Answers from the epigenome.

Authors: Sadler, Kirsten C; Storer, Mekayla A; Bayin, N Sumru

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/388215

Thesis Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.

Pedrosa, Pablo; Zhang, Zhenguang; Nuñez-Quintela, Victor et al. · 2024 · University of Cambridge · DOI

Full title: Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.

Authors: Pedrosa, Pablo; Zhang, Zhenguang; Nuñez-Quintela, Victor; Macias, David; Ge, Jianfeng; Denholm, Mary; Dyas, Anna; Estevez-Souto, Valentin; Lado-Fernandez, Patricia; Gonzalez, Patricia; Gomez, Maria; Martin, Jose Ezequiel; Da Silva-Alvarez, Sabela; Collado, Manuel; Muñoz-Espín, Daniel

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/376313

Thesis Reprogramming of human cancer cells towards induced pluripotency as a tool to study the influence of epigenetic modifications on the tumor phenotype

Bernhardt, Mathias · 2015 · Heidelberg University · DOI

Full title: Reprogramming of human cancer cells towards induced pluripotency as a tool to study the influence of epigenetic modifications on the tumor phenotype

Authors: Bernhardt, Mathias

Year: 2015

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/18585/1/PhD%20thesis_MB_PDF_A_1A.pdf

Thesis Partial reprogramming of melanoma cells mimics the phenotype switch and reveals SNAI3 as a novel invasion-associated marker

Knappe, Nathalie · 2015 · Heidelberg University · DOI

Full title: Partial reprogramming of melanoma cells mimics the phenotype switch and reveals SNAI3 as a novel invasion-associated marker

Authors: Knappe, Nathalie

Year: 2015

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/18723/1/DissertationNathalieKnappe.pdf.pdf

Thesis Cellular metabolic profiles as potential indicators of variability in reprogramming potential

Hawrylyshyn, Eric · 2024 · University of Guelph · DOI

Full title: Cellular metabolic profiles as potential indicators of variability in reprogramming potential

Authors: Hawrylyshyn, Eric

Year: 2024

Venue: University of Guelph

DOI: https://hdl.handle.net/10214/28213

Thesis Small Molecule Approaches for Targeting Signaling Networks in Cancer and Cellular Reprogramming

Dabiri, Yasamin · 2020 · Heidelberg University · DOI

Full title: Small Molecule Approaches for Targeting Signaling Networks in Cancer and Cellular Reprogramming

Authors: Dabiri, Yasamin

Year: 2020

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/28984/1/2020_Thesis_Dabiri.pdf

Thesis DISSECTING THE REGULATORY LOGIC OF CELL FATE REPROGRAMMING THROUGH A MULTI-OMIC APPROACH

PANARIELLO, FRANCESCO · 2023 · Università degli Studi di Milano (AIR) · DOI

Full title: DISSECTING THE REGULATORY LOGIC OF CELL FATE REPROGRAMMING THROUGH A MULTI-OMIC APPROACH

Authors: PANARIELLO, FRANCESCO

Year: 2023

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1018340

Thesis Reprogramming human cells using SMAR vectors and Potentiation of H-1PV oncolysis by Ledipasvir

Hartley, Anna · 2025 · Heidelberg University · DOI

Full title: Reprogramming human cells using SMAR vectors and Potentiation of H-1PV oncolysis by Ledipasvir

Authors: Hartley, Anna

Year: 2025

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34990/1/PhD_Thesis_Anna_Hartley.pdf

Thesis AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Plesa, Alexandru · 2022 · Harvard University - DASH · DOI

Full title: AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Authors: Plesa, Alexandru

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37373691

Thesis Active repression of alternative cell fates safeguards hepatocyte identity

Lim, Bryce · 2025 · Heidelberg University · DOI

Full title: Active repression of alternative cell fates safeguards hepatocyte identity

Authors: Lim, Bryce

Year: 2025

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/33904/1/Active%20repression%20of%20alternative%20cell%20fates%20safeguards%20hepatocyte%20identity.pdf

Thesis Elucidating variation in somatic cell lines that influence reprogramming potential

Toorani, Tahmineh · 2020 · University of Guelph · DOI

Full title: Elucidating variation in somatic cell lines that influence reprogramming potential

Authors: Toorani, Tahmineh

Year: 2020

Venue: University of Guelph

DOI: http://hdl.handle.net/10214/17945

Thesis Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Griffin, Patrick T · 2023 · Harvard University - DASH · DOI

Full title: Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Authors: Griffin, Patrick T

Year: 2023

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375515

Thesis Studying the Epigenetic Regulation of Stem Cell Aging and Rejuvenation

Gorelov, Rebecca · 2024 · Harvard University - DASH · DOI

Full title: Studying the Epigenetic Regulation of Stem Cell Aging and Rejuvenation

Authors: Gorelov, Rebecca

Year: 2024

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37379852

Thesis Investigating molecular and regulatory boundaries of the pluripotent state

Sindhu-Bertrand, Camille Anne · 2018 · Harvard University - DASH · DOI

Full title: Investigating molecular and regulatory boundaries of the pluripotent state

Authors: Sindhu-Bertrand, Camille Anne

Year: 2018

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:37944941

Thesis Deciphering the Molecular Basis of Cellular Reprogramming by Mass Spectrometry-based Proteomics

Benevento, M. · 2014 · Utrecht University · DOI

Full title: Deciphering the Molecular Basis of Cellular Reprogramming by Mass Spectrometry-based Proteomics

Authors: Benevento, M.

Year: 2014

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/294765

Thesis Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Cleary, Brian Lowman; Lin, Stacie; Jaenisch, Rudolf et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Authors: Cleary, Brian Lowman; Lin, Stacie; Jaenisch, Rudolf; Regev, Aviv; Lander, Eric Steven

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/124366

Thesis Programming and reprogramming cellular identity

Marson, Alexander · 2008 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Programming and reprogramming cellular identity

Authors: Marson, Alexander

Year: 2008

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/43223

Thesis Reprogramming cellular fate using defined factors

Foreman, Ruth K. (Ruth Kjelgaard) · 2009 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Reprogramming cellular fate using defined factors

Authors: Foreman, Ruth K. (Ruth Kjelgaard)

Year: 2009

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/46810

Thesis Induced pluripotency and reprogramming by defined factors

Carey, Bryce W · 2011 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Induced pluripotency and reprogramming by defined factors

Authors: Carey, Bryce W

Year: 2011

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/65752

Thesis Transdifferentiation of fibroblasts to neural stem cells

Cassady, John P · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Transdifferentiation of fibroblasts to neural stem cells

Authors: Cassady, John P

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/83634

Thesis Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

Saad, Norazalina · 2016 · University of Nottingham · DOI

Full title: Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

Authors: Saad, Norazalina

Year: 2016

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/36226/1/Final%20Thesis%20Norazalina%20Saad.pdf

Thesis Developing a model system to investigate the epigenetic mechanisms underlying pluripotency in human cells

Matsa, Elena · 2010 · University of Nottingham · DOI

Full title: Developing a model system to investigate the epigenetic mechanisms underlying pluripotency in human cells

Authors: Matsa, Elena

Year: 2010

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/14019/1/523599.pdf

Thesis Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

Leong, Yeh Chwan · 2018 · University of Nottingham · DOI

Full title: Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

Authors: Leong, Yeh Chwan

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/53330/1/PhD%20thesis%20Leong%20Yeh%20Chwan%20.pdf

Thesis Reprogramming of the mouse Nanog gene in amphibian oocyte extracts

Bereketoğlu, Sidar · 2016 · University of Nottingham · DOI

Full title: Reprogramming of the mouse Nanog gene in amphibian oocyte extracts

Authors: Bereketoğlu, Sidar

Year: 2016

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/38790/1/BEREKETOGLU_S_PHDTHESIS.pdf

Thesis Gene expression network analysis of the routes to pluripotency

Amaral, Fabio M R · 2018 · University of Nottingham · DOI

Full title: Gene expression network analysis of the routes to pluripotency

Authors: Amaral, Fabio M R

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/49714/1/Thesis_2018.pdf

Thesis Neuronal Reprogramming to Study Human Brain Aging and Disease

Herdy, Joseph · 2023 · University of California, San Diego (UCSD) · DOI

Full title: Neuronal Reprogramming to Study Human Brain Aging and Disease

Authors: Herdy, Joseph

Year: 2023

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0g70b3nb

Thesis Integrative genomic analysis of cell fate conversion

Li, Zhe · 2014 · University of California, San Diego (UCSD) · DOI

Full title: Integrative genomic analysis of cell fate conversion

Authors: Li, Zhe

Year: 2014

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/8zb078tv

Thesis Mechanisms of Transdifferentiation and Regeneration

Madhavan, Mayur C. · 2005 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Mechanisms of Transdifferentiation and Regeneration

Authors: Madhavan, Mayur C.

Year: 2005

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=miami1133554812

Thesis Generation of an HVS-based episomally maintained gene delivery system for reprogramming adult somatic cells

Brown, Hannah Frances · 2012 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Generation of an HVS-based episomally maintained gene delivery system for reprogramming adult somatic cells

Authors: Brown, Hannah Frances

Year: 2012

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/4445/1/Corrected%20Thesis.pdf

Thesis The Genetics and Epigenetics of Induced Pluripotent Stem Cells

Gore, Athurva Jayavant · 2013 · University of California, San Diego (UCSD) · DOI

Full title: The Genetics and Epigenetics of Induced Pluripotent Stem Cells

Authors: Gore, Athurva Jayavant

Year: 2013

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/45j1149s

Thesis The Kruppel-like Factors in Aging and Aging Associated Pathology

Hsieh, Paishiun Nelson · 2018 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: The Kruppel-like Factors in Aging and Aging Associated Pathology

Authors: Hsieh, Paishiun Nelson

Year: 2018

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1522942623451445

Thesis Studies on the Mechanism behind Retinal Pigment Epithelium (RPE) Reprogramming

Lu, Tianlin · 2019 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Studies on the Mechanism behind Retinal Pigment Epithelium (RPE) Reprogramming

Authors: Lu, Tianlin

Year: 2019

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=miami1575301308695243

Thesis An mRNA-reprogramming method with improved kinetics and efficiency and the successful transdifferentiation of human fibroblasts using modified mRNA

Preskey, David Alexander · 2017 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: An mRNA-reprogramming method with improved kinetics and efficiency and the successful transdifferentiation of human fibroblasts using modified mRNA

Authors: Preskey, David Alexander

Year: 2017

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/18242/1/20170705%20Thesis%2035%20DP.pdf

Thesis From gene therapy to somatic mutagenesis : insights into the common Hutchinson-Gilford progeria syndrome mutation

Daniel Whisenant (18649048) · 2022 · Karolinska Institutet · DOI

Full title: From gene therapy to somatic mutagenesis : insights into the common Hutchinson-Gilford progeria syndrome mutation

Authors: Daniel Whisenant (18649048)

Year: 2022

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26924155

Thesis Using Cellular Reprogramming and CRISPR Technologies for the Study of Neurodegeneration and the Development of Cell-Based Therapies

Urrutia Cabrera, Daniel · 2023 · University of Melbourne · DOI

Full title: Using Cellular Reprogramming and CRISPR Technologies for the Study of Neurodegeneration and the Development of Cell-Based Therapies

Authors: Urrutia Cabrera, Daniel

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/336979

Thesis Reprogramming human keratinocytes: a non-viral, microRNA approach

Lewis, Fiona · University of Liverpool · DOI

Full title: Reprogramming human keratinocytes: a non-viral, microRNA approach

Authors: Lewis, Fiona

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/7073/1/LewisFio_July2012_7073.pdf

Thesis The Role Of Active Dna Demethylation In Mammalian Epigenetic Reprogramming

Caldwell, Blake Alexander · 2023 · University of Pennsylvania · DOI

Full title: The Role Of Active Dna Demethylation In Mammalian Epigenetic Reprogramming

Authors: Caldwell, Blake Alexander

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/31559

Thesis A Systems Biology Analysis of Cell Cycle Arrest Suggests that Modular Activation of Stress Responses Underlies Heterogeneous Cellular Senescence and Quiescence Phenotypes

Avelar, Roberto · 2023 · University of Liverpool · DOI

Full title: A Systems Biology Analysis of Cell Cycle Arrest Suggests that Modular Activation of Stress Responses Underlies Heterogeneous Cellular Senescence and Quiescence Phenotypes

Authors: Avelar, Roberto

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3173246/1/201329530_Jan2023.pdf

Thesis BEYOND LUCK OF THE DRAW: UNCOVERING CELL-INTRINSIC DETERMINANTS IN REPROGRAMMING SOMATIC CELLS TO PLURIPOTENCY

Jain, Naveen · 2023 · University of Pennsylvania · DOI

Full title: BEYOND LUCK OF THE DRAW: UNCOVERING CELL-INTRINSIC DETERMINANTS IN REPROGRAMMING SOMATIC CELLS TO PLURIPOTENCY

Authors: Jain, Naveen

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/59121

Thesis Targeted Epigenetic Editing to Increase Adult Pancreatic Β-Cell Proliferation

Bernstein, Diana Lynne · 2023 · University of Pennsylvania · DOI

Full title: Targeted Epigenetic Editing to Increase Adult Pancreatic Β-Cell Proliferation

Authors: Bernstein, Diana Lynne

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/28440

Thesis EPIGENETIC AND ENVIRONMENTAL DETERMINANTS OF AGING AND LIFESPAN

Bertucci, Emily Marie · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: EPIGENETIC AND ENVIRONMENTAL DETERMINANTS OF AGING AND LIFESPAN

Authors: Bertucci, Emily Marie

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/3580/files/2022-11-23_BERTUCCI_DISSERTATION_FINAL.pdf

Thesis The knockdown of Dnmt1 using small inhibitory RNA:a method to assist in the reprogramming of a donor genome during nuclear transfer

Adams, Allison Marie · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: The knockdown of Dnmt1 using small inhibitory RNA:a method to assist in the reprogramming of a donor genome during nuclear transfer

Authors: Adams, Allison Marie

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/20700/files/adams_allison_m_200412_ms.pdf

Thesis Analysis of the applicability of iPS cell-based approaches to bypass senescence and to re-establish rejuvenation features in human MSCs from aged individuals

Megges, Matthias · 2016 · Freie Universität Berlin (Refubium) · DOI

Full title: Analysis of the applicability of iPS cell-based approaches to bypass senescence and to re-establish rejuvenation features in human MSCs from aged individuals

Authors: Megges, Matthias

Year: 2016

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/3452

Thesis Uncovering the bona fide quiescence transcriptome of aged muscle stem cells after systemic rejuvenation

Ngan, Lok Pui · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Uncovering the bona fide quiescence transcriptome of aged muscle stem cells after systemic rejuvenation

Authors: Ngan, Lok Pui

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-138540

Thesis Viral and non-viral generation and characterization of induced pluripotent stem cells from human amniotic fluid cells

Drews, Katharina · 2012 · Freie Universität Berlin (Refubium) · DOI

Full title: Viral and non-viral generation and characterization of induced pluripotent stem cells from human amniotic fluid cells

Authors: Drews, Katharina

Year: 2012

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/7715

Thesis Molecular mechanisms involved in the induction of pluripotency

Ruiz Acero, Guifré · 2012 · Freie Universität Berlin (Refubium) · DOI

Full title: Molecular mechanisms involved in the induction of pluripotency

Authors: Ruiz Acero, Guifré

Year: 2012

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/118

Thesis Efeitos de diferentes tensões de oxigênio na eficiência da reprogramação e manutenção de células-tronco pluripotentes induzidas de equino

Castro, Raquel Vasconcelos Guimarães de [UNESP] · 2020 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Efeitos de diferentes tensões de oxigênio na eficiência da reprogramação e manutenção de células-tronco pluripotentes induzidas de equino

Authors: Castro, Raquel Vasconcelos Guimarães de [UNESP]

Year: 2020

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/193447

Thesis Statistical Modelling for Cell Reprogramming

Tran, Andy · 2021 · University of Sydney · DOI

Full title: Statistical Modelling for Cell Reprogramming

Authors: Tran, Andy

Year: 2021

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/26580

Thesis Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming

Villafranca Locher, Maria Cristina · 2018 · Virginia Tech - VTechWorks · DOI

Full title: Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming

Authors: Villafranca Locher, Maria Cristina

Year: 2018

Venue: Virginia Tech - VTechWorks

DOI: http://hdl.handle.net/10919/82864

Thesis Reprogramming of human somatic cells using epigenetic and non-genetic methods

Han, Jinnuo · 2010 · UNSW Sydney · DOI

Full title: Reprogramming of human somatic cells using epigenetic and non-genetic methods

Authors: Han, Jinnuo

Year: 2010

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/45452

Thesis Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming

Romanazzo, S; https://orcid.org/0000-0002-7074-1248; Lin, K et al. · 2020 · UNSW Sydney · DOI

Full title: Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming

Authors: Romanazzo, S ; https://orcid.org/0000-0002-7074-1248; Lin, K; Srivastava, P; Kilian, KA ; https://orcid.org/0000-0002-8963-9796

Year: 2020

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_76936

Thesis Strategies for gene editing using the crispr system for the generation of genetically engineered livestock

Oliveira, Gabriella Borba de · 2021 · Universidade Federal do Rio Grande do Sul – LUME · DOI

Full title: Strategies for gene editing using the crispr system for the generation of genetically engineered livestock

Authors: Oliveira, Gabriella Borba de

Year: 2021

Venue: Universidade Federal do Rio Grande do Sul – LUME

DOI: http://hdl.handle.net/10183/233179

Thesis Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

Jullien, J; Vodnala, M; Pasque, V et al. · 2017 · University of Cambridge · DOI

Full title: Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

Authors: Jullien, J; Vodnala, M; Pasque, V; Oikawa, M; Miyamoto, K; Allen, G; David, SA; Brochard, V; Wang, S; Bradshaw, C; Koseki, H; Sartorelli, V; Beaujean, N; Gurdon, J

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/263488

Thesis In Vitro Models of Cellular Dedifferentiation for Regenerative Medicine

Williams, Kaylyn Renee · 2018 · Virginia Tech - VTechWorks · DOI

Full title: In Vitro Models of Cellular Dedifferentiation for Regenerative Medicine

Authors: Williams, Kaylyn Renee

Year: 2018

Venue: Virginia Tech - VTechWorks

DOI: http://hdl.handle.net/10919/83715

Thesis Reprogramming of somatic cells: a tool for modelling neurodegenerative diseases

Chung, Henry · 2011 · UNSW Sydney · DOI

Full title: Reprogramming of somatic cells: a tool for modelling neurodegenerative diseases

Authors: Chung, Henry

Year: 2011

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/51665

Thesis Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.

Pereira, Allwyn; Diwakar, Jeisimhan; Masserdotti, Giacomo et al. · 2024 · University of Cambridge · DOI

Full title: Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.

Authors: Pereira, Allwyn; Diwakar, Jeisimhan; Masserdotti, Giacomo; Beşkardeş, Sude; Simon, Tatiana; So, Younju; Martín-Loarte, Lucía; Bergemann, Franziska; Vasan, Lakshmy; Schauer, Tamas; Danese, Anna; Bocchi, Riccardo; Colomé-Tatché, Maria; Schuurmans, Carol; Philpott, Anna; Straub, Tobias; Bonev, Boyan; Götz, Magdalena

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/371198

Thesis Stochastic modelling of epigenetic regulation: analysis of its heterogeneity and its implications in cell plasticity

Folguera Blasco, Núria · 2019 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Stochastic modelling of epigenetic regulation: analysis of its heterogeneity and its implications in cell plasticity

Authors: Folguera Blasco, Núria

Year: 2019

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/666963

Thesis Induced pluripotent stem cells reprogramming: Epigenetics and applications in the regenerative medicine

Ferreira, Julio Cesar Batista · 2017 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Induced pluripotent stem cells reprogramming: Epigenetics and applications in the regenerative medicine

Authors: Ferreira, Julio Cesar Batista

Year: 2017

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1590/1806-9282.63.02.180

Thesis Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming

Khaw, Swea-Ling; Koh, Cheng-Gee; Lim, Bing et al. · 2015 · Nanyang Technological University (NTU) · DOI

Full title: Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming

Authors: Khaw, Swea-Ling; Koh, Cheng-Gee; Lim, Bing; Chua, Min-Wen; Ng, Shyh-Chang

Year: 2015

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/103359

Thesis Partial Reprogramming: A Shortcut to Rejuvenation

Lam, David Du · 2019 · University of California, San Diego (UCSD) · DOI

Full title: Partial Reprogramming: A Shortcut to Rejuvenation

Authors: Lam, David Du

Year: 2019

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/9cz440mz

Thesis Prevention of cellular aging in vitro

Kubovčák, Matej · 2023 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Prevention of cellular aging in vitro

Authors: Kubovčák, Matej

Year: 2023

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/181315

Thesis Hearts and bones': the ups and downs of plasticity' in stem cell biology

Bonfanti, Paola; Barrandon, Yann; Cossu, Giulio · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Hearts and bones': the ups and downs of plasticity' in stem cell biology

Authors: Bonfanti, Paola; Barrandon, Yann; Cossu, Giulio

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80760

Thesis Confounding factors from inducible systems for spatiotemporal gene expression regulation

Wuest, Rob C. I.; Houtkooper, Riekelt H.; Auwerx, Johan · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Confounding factors from inducible systems for spatiotemporal gene expression regulation

Authors: Wuest, Rob C. I.; Houtkooper, Riekelt H.; Auwerx, Johan

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/170461

Thesis Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Unzu, Carmen; Friedli, Marc; Bosman, Alexis et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Authors: Unzu, Carmen; Friedli, Marc; Bosman, Alexis; Jaconi, Marisa E.; Wildhaber, Barbara E.; Rougemont, Anne-Laure; Unzu, Carmen; Friedli, Marc; Bosman, Alexis; Jaconi, Marisa E.; Wildhaber, Barbara E.

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/128018

Thesis Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

Hung, SSC; Van Bergen, NJ; Jackson, S et al. · 2018 · University of Melbourne · DOI

Full title: Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

Authors: Hung, SSC; Van Bergen, NJ; Jackson, S; Liang, H; Mackey, DA; Hernández, D; Lim, SY; Hewitt, AW; Trounce, I; Pébay, A; Wong, RCB

Year: 2018

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/212358

Thesis Metabolism is a key regulator of induced pluripotent stem cell reprogramming

Spyrou, J; Gardner, DK; Harvey, AJ · 2020 · University of Melbourne · DOI

Full title: Metabolism is a key regulator of induced pluripotent stem cell reprogramming

Authors: Spyrou, J; Gardner, DK; Harvey, AJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/245921

Thesis Potentials of cellular reprogramming as a novel strategy for neuroregeneration

Fang, L; El Wazan, L; Tan, C et al. · 2020 · University of Melbourne · DOI

Full title: Potentials of cellular reprogramming as a novel strategy for neuroregeneration

Authors: Fang, L; El Wazan, L; Tan, C; Nguyen, T; Hung, SSC; Hewitt, AW; Wong, RCB

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/249971

Thesis Using transcription factors for direct reprogramming of neurons in vitro

El Wazan, L; Urrutia-Cabrera, D; Wong, RCB · 2020 · University of Melbourne · DOI

Full title: Using transcription factors for direct reprogramming of neurons in vitro

Authors: El Wazan, L; Urrutia-Cabrera, D; Wong, RCB

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/246451

Thesis BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming

Kim, EJY; Anko, ML; Flensberg, C et al. · 2020 · University of Melbourne · DOI

Full title: BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming

Authors: Kim, EJY; Anko, ML; Flensberg, C; Majewski, IJ; Geng, FS; Firas, J; Huang, DCS; van Delft, MF; Heath, JK

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/253104

Thesis Corrigendum: Potentials of cellular reprogramming as a novel strategy for neuroregeneration (Front. Cell. Neurosci., (2018), 12, 10.3389/fncel.2018.00460)

Fang, L; El Wazan, L; Tan, C et al. · 2020 · University of Melbourne · DOI

Full title: Corrigendum: Potentials of cellular reprogramming as a novel strategy for neuroregeneration (Front. Cell. Neurosci., (2018), 12, 10.3389/fncel.2018.00460)

Authors: Fang, L; El Wazan, L; Tan, C; Nguyen, T; Hung, SSC; Hewitt, AW; Wong, RCB

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/251180

Thesis Induction of pluripotency in adult equine fibroblasts without c-MYC

Khodadadi, K; Sumer, H; Pashaiasl, M et al. · 2020 · University of Melbourne · DOI

Full title: Induction of pluripotency in adult equine fibroblasts without c-MYC

Authors: Khodadadi, K; Sumer, H; Pashaiasl, M; Lim, S; Williamson, M; Verma, PJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/255787

Thesis Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts

Liu, J; Ashton, MP; Sumer, H et al. · 2020 · University of Melbourne · DOI

Full title: Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts

Authors: Liu, J; Ashton, MP; Sumer, H; O'Bryan, MK; Brodnicki, TC; Verma, PJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/257005

Thesis An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

Lee, DS; Shin, JY; Tonge, PD et al. · 2020 · University of Melbourne · DOI

Full title: An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

Authors: Lee, DS; Shin, JY; Tonge, PD; Puri, MC; Lee, S; Park, H; Lee, WC; Hussein, SMI; Bleazard, T; Yun, JY; Kim, J; Li, M; Cloonan, N; Wood, D; Clancy, JL; Mosbergen, R; Yi, JH; Yang, KS; Kim, H; Rhee, H; Wells, CA; Preiss, T; Grimmond, SM; Rogers, IM; Nagy, A; Seo, JS

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/258237

Thesis DNA methylation status correlates with adult β-cell regeneration capacity

Khurana, I; Al-Hasani, K; Maxwell, S et al. · 2021 · University of Melbourne · DOI

Full title: DNA methylation status correlates with adult β-cell regeneration capacity

Authors: Khurana, I; Al-Hasani, K; Maxwell, S; K.N, H; Okabe, J; Cooper, ME; Collombat, P; El-Osta, A

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/272983

Thesis Multi-tissue DNA methylation age predictor in mouse

Stubbs, TM; Bonder, MJ; Stark, A-K et al. · 2021 · University of Melbourne · DOI

Full title: Multi-tissue DNA methylation age predictor in mouse

Authors: Stubbs, TM; Bonder, MJ; Stark, A-K; Krueger, F; von Meyenn, F; Stegle, O; Reik, W

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/273088

Thesis Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle

Voisin, S; Jacques, M; Landen, S et al. · 2022 · University of Melbourne · DOI

Full title: Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle

Authors: Voisin, S; Jacques, M; Landen, S; Harvey, NR; Haupt, LM; Griffiths, LR; Gancheva, S; Ouni, M; Jähnert, M; Ashton, KJ; Coffey, VG; Thompson, JLM; Doering, TM; Gabory, A; Junien, C; Caiazzo, R; Verkindt, H; Raverdy, V; Pattou, F; Froguel, P; Craig, JM; Blocquiaux, S; Thomis, M; Sharples, AP; Schürmann, A; Roden, M; Horvath, S; Eynon, N

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/301767

Thesis Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

Nefzger, CM; Jardé, T; Srivastava, A et al. · 2022 · University of Melbourne · DOI

Full title: Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

Authors: Nefzger, CM; Jardé, T; Srivastava, A; Schroeder, J; Rossello, FJ; Horvay, K; Prasko, M; Paynter, JM; Chen, J; Weng, CF; Sun, YBY; Liu, X; Chan, E; Deshpande, N; Chen, X; Li, YJ; Pflueger, J; Engel, RM; Knaupp, AS; Tsyganov, K; Nilsson, SK; Lister, R; Rackham, OJL; Abud, HE; Polo, JM

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316555

Thesis Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation

Arez, M; Eckersley-Maslin, M; Klobučar, T et al. · 2022 · University of Melbourne · DOI

Full title: Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation

Authors: Arez, M; Eckersley-Maslin, M; Klobučar, T; von Gilsa Lopes, J; Krueger, F; Mupo, A; Raposo, AC; Oxley, D; Mancino, S; Gendrel, AV; Bernardes de Jesus, B; da Rocha, ST

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/318347

Thesis Microencapsulation-based cell therapies

Marikar, SN; El-Osta, A; Johnston, A et al. · 2022 · University of Melbourne · DOI

Full title: Microencapsulation-based cell therapies

Authors: Marikar, SN; El-Osta, A; Johnston, A; Such, G; Al-Hasani, K

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316379

Thesis Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity

Huyghe, A; Furlan, G; Schroeder, J et al. · 2022 · University of Melbourne · DOI

Full title: Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity

Authors: Huyghe, A; Furlan, G; Schroeder, J; Cascales, E; Trajkova, A; Ruel, M; Stüder, F; Larcombe, M; Yang Sun, YB; Mugnier, F; De Matteo, L; Baygin, A; Wang, J; Yu, Y; Rama, N; Gibert, B; Kielbassa, J; Tonon, L; Wajda, P; Gadot, N; Brevet, M; Siouda, M; Mulligan, P; Dante, R; Liu, P; Gronemeyer, H; Mendoza-Parra, M; Polo, JM; Lavial, F

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/320010

Thesis Non-viral direct reprogramming strategies for the creation of insulin producing cells for type 1 diabetes

Risser, Ian · 2020 · The Ohio State University · DOI

Full title: Non-viral direct reprogramming strategies for the creation of insulin producing cells for type 1 diabetes

Authors: Risser, Ian

Year: 2020

Venue: The Ohio State University

DOI: http://hdl.handle.net/1811/92081

Thesis Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

Isaksson, Johannes · 2018 · Lund University Student Papers · DOI

Full title: Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

Authors: Isaksson, Johannes

Year: 2018

Venue: Lund University Student Papers

DOI: http://lup.lub.lu.se/student-papers/record/8958666

Thesis Neuronal Reprogramming via Nanochannel Electroporation

Ortiz Villabona, Cristina · 2015 · The Ohio State University · DOI

Full title: Neuronal Reprogramming via Nanochannel Electroporation

Authors: Ortiz Villabona, Cristina

Year: 2015

Venue: The Ohio State University

DOI: http://hdl.handle.net/1811/68920

Thesis Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Yeola, A; Subramanian, S; Oliver, RA et al. · 2022 · University of Melbourne · DOI

Full title: Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Authors: Yeola, A; Subramanian, S; Oliver, RA; Lucas, CA; Thoms, JAI; Yan, F; Olivier, J; Chacon, D; Tursky, ML; Srivastava, P; Potas, JR; Hung, T; Power, C; Hardy, P; Ma, DD; Kilian, KA; McCarroll, J; Kavallaris, M; Hesson, LB; Beck, D; Curtis, DJ; Wong, JWH; Hardeman, EC; Walsh, WR; Mobbs, R; Chandrakanthan, V; Pimanda, JE

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/304557

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Metadata only

Paper Partial Reprogramming As An Emerging Strategy for Safe Induced Cell Generation and Rejuvenation.

Lehmann, Marianne; Canatelli-Mallat, Martina; Chiavellini, Priscila et al. · 2019 · Current gene therapy · DOI

Full title: Partial Reprogramming As An Emerging Strategy for Safe Induced Cell Generation and Rejuvenation.

Authors: Lehmann, Marianne; Canatelli-Mallat, Martina; Chiavellini, Priscila; Cónsole, Gloria M; Gallardo, Maria D; Goya, Rodolfo G

Year: 2019

Venue: Current gene therapy

DOI: https://doi.org/10.2174/1566523219666190902154511

Paper Can iPSCs Turn Back Time? Prospects and Pitfalls in Age Reversal.

Ahmad, Usama; Kumar, Dinesh; Faiyazuddin, Md · 2025 · Current stem cell research & therapy · DOI

Full title: Can iPSCs Turn Back Time? Prospects and Pitfalls in Age Reversal.

Authors: Ahmad, Usama; Kumar, Dinesh; Faiyazuddin, Md

Year: 2025

Venue: Current stem cell research & therapy

DOI: https://doi.org/10.2174/011574888X400606250721112037

Paper Partial cellular reprogramming stably restores the stemness of senescent epidermal stem cells.

Su, Y-R; Gu, S-M; Liu, Y-R et al. · 2023 · European review for medical and pharmacological sciences · DOI

Full title: Partial cellular reprogramming stably restores the stemness of senescent epidermal stem cells.

Authors: Su, Y-R; Gu, S-M; Liu, Y-R; Cheng, Y-Q; Wan, Q; Sang, X; Chen, M-H; Liu, W-Q; Shi, Q; Liu, C; Liu, Y; Li, C-Y; Wang, Z-C; Wang, X-R

Year: 2023

Venue: European review for medical and pharmacological sciences

DOI: https://doi.org/10.26355/eurrev_202306_32774

Paper Synergistic Anti-Ageing through Senescent Cells Specific Reprogramming.

Chen, Rui; Skutella, Thomas · 2022 · Cells · DOI

Full title: Synergistic Anti-Ageing through Senescent Cells Specific Reprogramming.

Authors: Chen, Rui; Skutella, Thomas

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11050830

Paper Partial Reprogramming Is Conserved from Insect to Mammal.

Tolwinski, Nicholas S; Fong, Sheng; Shankar, Sujithra et al. · 2026 · Cells · DOI

Full title: Partial Reprogramming Is Conserved from Insect to Mammal.

Authors: Tolwinski, Nicholas S; Fong, Sheng; Shankar, Sujithra; Gruber, Jan

Year: 2026

Venue: Cells

DOI: https://doi.org/10.3390/cells15020168

Paper Partial Cell Fate Transitions to Promote Cardiac Regeneration.

Yang, Jianchang · 2024 · Cells · DOI

Full title: Partial Cell Fate Transitions to Promote Cardiac Regeneration.

Authors: Yang, Jianchang

Year: 2024

Venue: Cells

DOI: https://doi.org/10.3390/cells13232002

Paper The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming.

Mendoza, Gracia; González-Pastor, Rebeca; Sánchez, Juan Miguel et al. · 2023 · Cells · DOI

Full title: The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming.

Authors: Mendoza, Gracia; González-Pastor, Rebeca; Sánchez, Juan Miguel; Arce-Cerezo, Altamira; Quintanilla, Miguel; Moreno-Bueno, Gema; Pujol, Anna; Belmar-López, Carolina; de Martino, Alba; Riu, Efrén; Rodriguez, Tristan A; Martin-Duque, Pilar

Year: 2023

Venue: Cells

DOI: https://doi.org/10.3390/cells12091338

Paper Cellular Reprogramming-A Model for Melanoma Cellular Plasticity.

Granados, Karol; Poelchen, Juliane; Novak, Daniel et al. · 2020 · International journal of molecular sciences · DOI

Full title: Cellular Reprogramming-A Model for Melanoma Cellular Plasticity.

Authors: Granados, Karol; Poelchen, Juliane; Novak, Daniel; Utikal, Jochen

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21218274

Paper Adult Stem Cells and Diseases of Aging

Boyette, Lisa; Tuan, Rocky S. · 2014 · Journal of Clinical Medicine · DOI

Full title: Adult Stem Cells and Diseases of Aging

Authors: Boyette, Lisa; Tuan, Rocky S.

Year: 2014

Venue: Journal of Clinical Medicine

DOI: https://doi.org/10.3390/jcm3010088

Paper Partial Reprogramming Exerts a Rejuvenating Effect on Human Mesenchymal Stem Cells That Underwent Replicative Senescence in Culture.

Ivanova, Julia; Shorokhova, Mariia; Pugovkina, Natalia et al. · 2024 · International journal of molecular sciences · DOI

Full title: Partial Reprogramming Exerts a Rejuvenating Effect on Human Mesenchymal Stem Cells That Underwent Replicative Senescence in Culture.

Authors: Ivanova, Julia; Shorokhova, Mariia; Pugovkina, Natalia; Kozhukharova, Irina; Alekseenko, Larisa; Guriev, Nikita; Kuneev, Ivan; Domnina, Alisa; Grinchuk, Tatiana; Zemelko, Victoria; Lyublinskaya, Olga

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252312533

Paper Nanoparticles: Taking a Unique Position in Medicine

Joseph, Tomy Muringayil; Mahapatra, Debarshi Kar; Esmaeili, Amin et al. · 2023 · Nanomaterials · DOI

Full title: Nanoparticles: Taking a Unique Position in Medicine

Authors: Joseph, Tomy Muringayil; Mahapatra, Debarshi Kar; Esmaeili, Amin; Piszczyk, Łukasz; Hasanin, Mohamed S.; Kattali, Mashhoor; Haponiuk, Józef T.; Thomas, Sabu

Year: 2023

Venue: Nanomaterials

DOI: https://doi.org/10.3390/nano13030574

Paper Oxygen: A Stimulus, Not "Only" a Drug.

Balestra, Costantino; Kot, Jacek · 2021 · Medicina (Kaunas, Lithuania) · DOI

Full title: Oxygen: A Stimulus, Not "Only" a Drug.

Authors: Balestra, Costantino; Kot, Jacek

Year: 2021

Venue: Medicina (Kaunas, Lithuania)

DOI: https://doi.org/10.3390/medicina57111161

Paper Epigenetic rejuvenation by partial reprogramming.

Puri, Deepika; Wagner, Wolfgang · 2023 · BioEssays : news and reviews in molecular, cellular and developmental biology · DOI

Full title: Epigenetic rejuvenation by partial reprogramming.

Authors: Puri, Deepika; Wagner, Wolfgang

Year: 2023

Venue: BioEssays : news and reviews in molecular, cellular and developmental biology

DOI: https://doi.org/10.1002/bies.202200208

Paper Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis.

Wang, Peilin; Wang, Renyuan; Huo, Yilin et al. · 2025 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis.

Authors: Wang, Peilin; Wang, Renyuan; Huo, Yilin; Peng, Ying; Fu, Chuanliang; Hu, Yi; Ren, Zun; Mulat, Yersen; Zhang, Hao; Jiang, Dongsheng; Lin, Haodong

Year: 2025

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202511019

Paper Pancreas organogenesis: From bud to plexus to gland

Pan, Fong Cheng; Wright, Chris · 2011 · Developmental Dynamics · DOI

Full title: Pancreas organogenesis: From bud to plexus to gland

Authors: Pan, Fong Cheng; Wright, Chris

Year: 2011

Venue: Developmental Dynamics

DOI: https://doi.org/10.1002/dvdy.22584

Paper Epithelial‐mesenchymal Transition and Cancer Stem Cells: At the Crossroads of Differentiation and Dedifferentiation

Wang, Hanmin; Unternaehrer, Juli · 2018 · Developmental Dynamics · DOI

Full title: Epithelial‐mesenchymal Transition and Cancer Stem Cells: At the Crossroads of Differentiation and Dedifferentiation

Authors: Wang, Hanmin; Unternaehrer, Juli

Year: 2018

Venue: Developmental Dynamics

DOI: https://doi.org/10.1002/dvdy.24678

Paper The Future of Medicinal Chemistry

Hoffmann, Torsten; Metternich, Rainer · 2012 · Angewandte Chemie International Edition · DOI

Full title: The Future of Medicinal Chemistry

Authors: Hoffmann, Torsten; Metternich, Rainer

Year: 2012

Venue: Angewandte Chemie International Edition

DOI: https://doi.org/10.1002/anie.201201677

Paper Partial reprogramming as a therapeutic approach for heart disease: A state-of-the-art review.

Talkhabi, Mahmood · 2019 · Journal of cellular biochemistry · DOI

Full title: Partial reprogramming as a therapeutic approach for heart disease: A state-of-the-art review.

Authors: Talkhabi, Mahmood

Year: 2019

Venue: Journal of cellular biochemistry

DOI: https://doi.org/10.1002/jcb.28900

Paper Indirect Mechanisms of Transcription Factor-Mediated Gene Regulation during Cell Fate Changes.

Larcombe, Michael R; Hsu, Sheng; Polo, Jose M et al. · 2022 · Advanced genetics (Hoboken, N.J.) · DOI

Full title: Indirect Mechanisms of Transcription Factor-Mediated Gene Regulation during Cell Fate Changes.

Authors: Larcombe, Michael R; Hsu, Sheng; Polo, Jose M; Knaupp, Anja S

Year: 2022

Venue: Advanced genetics (Hoboken, N.J.)

DOI: https://doi.org/10.1002/ggn2.202200015

Paper Bone Aging, Cellular Senescence, and Osteoporosis

Pignolo, Robert J.; Law, Susan F.; Chandra, Abhishek · 2021 · JBMR Plus · DOI

Full title: Bone Aging, Cellular Senescence, and Osteoporosis

Authors: Pignolo, Robert J.; Law, Susan F.; Chandra, Abhishek

Year: 2021

Venue: JBMR Plus

DOI: https://doi.org/10.1002/jbm4.10488

Paper Adult Palatum as a Novel Source of Neural Crest-Related Stem Cells

Widera, Darius; Zander, Christin; Heidbreder, Meike et al. · 2009 · Stem Cells · DOI

Full title: Adult Palatum as a Novel Source of Neural Crest-Related Stem Cells

Authors: Widera, Darius; Zander, Christin; Heidbreder, Meike; Kasperek, Yvonne; Noll, Thomas; Seitz, Oliver; Saldamli, Belma; Sudhoff, Holger; Sader, Robert; Kaltschmidt, Christian; Kaltschmidt, Barbara

Year: 2009

Venue: Stem Cells

DOI: https://doi.org/10.1002/stem.104

Paper From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency

Meyer-Blazejewska, Ewa Anna; Call, Mindy K.; Yamanaka, Osamu et al. · 2010 · Stem Cells · DOI

Full title: From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency

Authors: Meyer-Blazejewska, Ewa Anna; Call, Mindy K.; Yamanaka, Osamu; Liu, Hongshan; Schlötzer‐Schrehardt, Ursula; Kruse, Friedrich E.; Kao, Winston W.‐Y.

Year: 2010

Venue: Stem Cells

DOI: https://doi.org/10.1002/stem.550

Paper Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.

Knappe, Nathalie; Novak, Daniel; Weina, Kasia et al. · 2016 · Stem cells (Dayton, Ohio) · DOI

Full title: Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.

Authors: Knappe, Nathalie; Novak, Daniel; Weina, Kasia; Bernhardt, Mathias; Reith, Maike; Larribere, Lionel; Hölzel, Michael; Tüting, Thomas; Gebhardt, Christoffer; Umansky, Viktor; Utikal, Jochen

Year: 2016

Venue: Stem cells (Dayton, Ohio)

DOI: https://doi.org/10.1002/stem.2284

Paper Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine

Knoepfler, Paul S. · 2009 · Stem Cells · DOI

Full title: Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine

Authors: Knoepfler, Paul S.

Year: 2009

Venue: Stem Cells

DOI: https://doi.org/10.1002/stem.37

Paper Human mesenchymal stem cells reprogram adult cardiomyocytes toward a progenitor-like state through partial cell fusion and mitochondria transfer.

Acquistapace, Adrien; Bru, Thierry; Lesault, Pierre-François et al. · 2011 · Stem cells (Dayton, Ohio) · DOI

Full title: Human mesenchymal stem cells reprogram adult cardiomyocytes toward a progenitor-like state through partial cell fusion and mitochondria transfer.

Authors: Acquistapace, Adrien; Bru, Thierry; Lesault, Pierre-François; Figeac, Florence; Coudert, Amélie E; le Coz, Olivier; Christov, Christo; Baudin, Xavier; Auber, Fréderic; Yiou, René; Dubois-Randé, Jean-Luc; Rodriguez, Anne-Marie

Year: 2011

Venue: Stem cells (Dayton, Ohio)

DOI: https://doi.org/10.1002/stem.632

Paper Reduction of Fibrosis and Scar Formation by Partial Reprogramming In Vivo.

Doeser, Markus C; Schöler, Hans R; Wu, Guangming · 2018 · Stem cells (Dayton, Ohio) · DOI

Full title: Reduction of Fibrosis and Scar Formation by Partial Reprogramming In Vivo.

Authors: Doeser, Markus C; Schöler, Hans R; Wu, Guangming

Year: 2018

Venue: Stem cells (Dayton, Ohio)

DOI: https://doi.org/10.1002/stem.2842

Paper A Highly Conductive 3D Cardiac Patch Fabricated Using Cardiac Myocytes Reprogrammed from Human Adipogenic Mesenchymal Stem Cells.

Abbasgholizadeh, Reza; Islas, Jose Francisco; Navran, Stephen et al. · 2020 · Cardiovascular engineering and technology · DOI

Full title: A Highly Conductive 3D Cardiac Patch Fabricated Using Cardiac Myocytes Reprogrammed from Human Adipogenic Mesenchymal Stem Cells.

Authors: Abbasgholizadeh, Reza; Islas, Jose Francisco; Navran, Stephen; Potaman, Vladimir N; Schwartz, Robert J; Birla, Ravi K

Year: 2020

Venue: Cardiovascular engineering and technology

DOI: https://doi.org/10.1007/s13239-019-00451-0

Paper Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury.

Tang, Yuewen; Cheng, Lin · 2017 · Protein & cell · DOI

Full title: Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury.

Authors: Tang, Yuewen; Cheng, Lin

Year: 2017

Venue: Protein & cell

DOI: https://doi.org/10.1007/s13238-017-0373-y

Paper Conserved biological processes in partial cellular reprogramming: Relevance to aging and rejuvenation.

Avelar, Roberto A; Palmer, Daniel; Kulaga, Anton Y et al. · 2025 · Ageing research reviews · DOI

Full title: Conserved biological processes in partial cellular reprogramming: Relevance to aging and rejuvenation.

Authors: Avelar, Roberto A; Palmer, Daniel; Kulaga, Anton Y; Fuellen, Georg

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2025.102737

Paper The Pathobiology of Skin Aging

Russell‐Goldman, Eleanor; Murphy, George J. · 2020 · American Journal Of Pathology · DOI

Full title: The Pathobiology of Skin Aging

Authors: Russell‐Goldman, Eleanor; Murphy, George J.

Year: 2020

Venue: American Journal Of Pathology

DOI: https://doi.org/10.1016/j.ajpath.2020.03.007

Paper Targeted partial reprogramming as a novel therapeutic strategy for age-related decline.

Rose, Max; Adashi, Eli Y · 2025 · Ageing research reviews · DOI

Full title: Targeted partial reprogramming as a novel therapeutic strategy for age-related decline.

Authors: Rose, Max; Adashi, Eli Y

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2025.102731

Paper The epigenetic rejuvenation promise: Partial reprogramming as a therapeutic strategy for aging and disease.

Li, Yuan-Yuan; Tay, Franklin R · 2026 · Ageing research reviews · DOI

Full title: The epigenetic rejuvenation promise: Partial reprogramming as a therapeutic strategy for aging and disease.

Authors: Li, Yuan-Yuan; Tay, Franklin R

Year: 2026

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2026.103009

Paper Transient or partial epigenetic reprogramming to overcome senescence in human keratinocyte cultures for skin engineering and rejuvenation.

Kardeh, Sina; Mazloomrezaei, Mohsen; Jalouli, Maryam et al. · 2021 · Burns : journal of the International Society for Burn Injuries · DOI

Full title: Transient or partial epigenetic reprogramming to overcome senescence in human keratinocyte cultures for skin engineering and rejuvenation.

Authors: Kardeh, Sina; Mazloomrezaei, Mohsen; Jalouli, Maryam; Faezi-Marian, Shima

Year: 2021

Venue: Burns : journal of the International Society for Burn Injuries

DOI: https://doi.org/10.1016/j.burns.2021.04.008

Paper In vivo partial cellular reprogramming enhances liver plasticity and regeneration.

Hishida, Tomoaki; Yamamoto, Mako; Hishida-Nozaki, Yuriko et al. · 2022 · Cell reports · DOI

Full title: In vivo partial cellular reprogramming enhances liver plasticity and regeneration.

Authors: Hishida, Tomoaki; Yamamoto, Mako; Hishida-Nozaki, Yuriko; Shao, Changwei; Huang, Ling; Wang, Chao; Shojima, Kensaku; Xue, Yuan; Hang, Yuqing; Shokhirev, Maxim; Memczak, Sebastian; Sahu, Sanjeeb Kumar; Hatanaka, Fumiyuki; Ros, Ruben Rabadan; Maxwell, Matthew B; Chavez, Jasmine; Shao, Yanjiao; Liao, Hsin-Kai; Martinez-Redondo, Paloma; Guillen-Guillen, Isabel; Hernandez-Benitez, Reyna; Esteban, Concepcion Rodriguez; Qu, Jing; Holmes, Michael C; Yi, Fei; Hickey, Raymond D; Garcia, Pedro Guillen; Delicado, Estrella Nuñez; Castells, Antoni; Campistol, Josep M; Yu, Yang; Hargreaves, Diana C; Asai, Akihiro; Reddy, Pradeep; Liu, Guang-Hui; Izpisua Belmonte, Juan Carlos

Year: 2022

Venue: Cell reports

DOI: https://doi.org/10.1016/j.celrep.2022.110730

Paper In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Ocampo, Alejandro; Reddy, Pradeep; Martinez-Redondo, Paloma et al. · 2016 · Cell · DOI

Full title: In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Authors: Ocampo, Alejandro; Reddy, Pradeep; Martinez-Redondo, Paloma; Platero-Luengo, Aida; Hatanaka, Fumiyuki; Hishida, Tomoaki; Li, Mo; Lam, David; Kurita, Masakazu; Beyret, Ergin; Araoka, Toshikazu; Vazquez-Ferrer, Eric; Donoso, David; Roman, Jose Luis; Xu, Jinna; Rodriguez Esteban, Concepcion; Nuñez, Gabriel; Nuñez Delicado, Estrella; Campistol, Josep M; Guillen, Isabel; Guillen, Pedro; Izpisua Belmonte, Juan Carlos

Year: 2016

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2016.11.052

Paper Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming.

Lu, Jinlong Y; Tu, William B; Li, Ronghui et al. · 2025 · Cell · DOI

Full title: Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming.

Authors: Lu, Jinlong Y; Tu, William B; Li, Ronghui; Weng, Mingxi; Sanketi, Bhargav D; Yuan, Baolei; Reddy, Pradeep; Rodriguez Esteban, Concepcion; Izpisua Belmonte, Juan Carlos

Year: 2025

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2025.07.031

Paper Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity.

Roux, Antoine E; Zhang, Chunlian; Paw, Jonathan et al. · 2022 · Cell systems · DOI

Full title: Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity.

Authors: Roux, Antoine E; Zhang, Chunlian; Paw, Jonathan; Zavala-Solorio, José; Malahias, Evangelia; Vijay, Twaritha; Kolumam, Ganesh; Kenyon, Cynthia; Kimmel, Jacob C

Year: 2022

Venue: Cell systems

DOI: https://doi.org/10.1016/j.cels.2022.05.002

Paper A new hypothetical model for pancreatic development based on change in the cell division orientation.

Vakilian, Mehrdad; Ghaedi, Kamran · 2021 · Gene · DOI

Full title: A new hypothetical model for pancreatic development based on change in the cell division orientation.

Authors: Vakilian, Mehrdad; Ghaedi, Kamran

Year: 2021

Venue: Gene

DOI: https://doi.org/10.1016/j.gene.2021.145607

Paper Rejuvenation of the Aging Heart: Molecular Determinants and Applications.

Alibhai, Faisal J; Li, Ren-Ke · 2024 · The Canadian journal of cardiology · DOI

Full title: Rejuvenation of the Aging Heart: Molecular Determinants and Applications.

Authors: Alibhai, Faisal J; Li, Ren-Ke

Year: 2024

Venue: The Canadian journal of cardiology

DOI: https://doi.org/10.1016/j.cjca.2024.03.004

Paper Unlocking regeneration: how partial reprogramming resembles tissue healing.

Adams, Melissa T; Jasper, Heinrich; Mosteiro, Lluc · 2025 · Current opinion in genetics & development · DOI

Full title: Unlocking regeneration: how partial reprogramming resembles tissue healing.

Authors: Adams, Melissa T; Jasper, Heinrich; Mosteiro, Lluc

Year: 2025

Venue: Current opinion in genetics & development

DOI: https://doi.org/10.1016/j.gde.2025.102351

Paper Reprogramming endothelial and vascular smooth muscle cells to prevent and treat hypertension.

Pernomian, Laena; Tan, Wenbin; McCarthy, Cameron et al. · 2023 · Medical hypotheses · DOI

Full title: Reprogramming endothelial and vascular smooth muscle cells to prevent and treat hypertension.

Authors: Pernomian, Laena; Tan, Wenbin; McCarthy, Cameron; Wenceslau, Camilla Ferreira

Year: 2023

Venue: Medical hypotheses

DOI: https://doi.org/10.1016/j.mehy.2023.111162

Paper Cancer as "rejuvenescence".

Ukraintseva, Svetlana V; Yashina, Anatoly I · 2004 · Annals of the New York Academy of Sciences · DOI

Full title: Cancer as "rejuvenescence".

Authors: Ukraintseva, Svetlana V; Yashina, Anatoly I

Year: 2004

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1196/annals.1297.032

Paper Cancer nanomedicine: a review of recent success in drug delivery

Tran, Stephanie; DeGiovanni, Peter-Joseph; Piel, Brandon et al. · 2017 · Clinical and Translational Medicine · DOI

Full title: Cancer nanomedicine: a review of recent success in drug delivery

Authors: Tran, Stephanie; DeGiovanni, Peter-Joseph; Piel, Brandon; Rai, Prakash

Year: 2017

Venue: Clinical and Translational Medicine

DOI: https://doi.org/10.1186/s40169-017-0175-0

Paper Age reprogramming: cell rejuvenation by partial reprogramming.

Singh, Prim B; Zhakupova, Assem · 2022 · Development (Cambridge, England) · DOI

Full title: Age reprogramming: cell rejuvenation by partial reprogramming.

Authors: Singh, Prim B; Zhakupova, Assem

Year: 2022

Venue: Development (Cambridge, England)

DOI: https://doi.org/10.1242/dev.200755

Paper Krüppel-like factors in mammalian stem cells and development

Bialkowska, Agnieszka B.; Yang, Vincent W.; Mallipattu, Sandeep K. · 2017 · Development · DOI

Full title: Krüppel-like factors in mammalian stem cells and development

Authors: Bialkowska, Agnieszka B.; Yang, Vincent W.; Mallipattu, Sandeep K.

Year: 2017

Venue: Development

DOI: https://doi.org/10.1242/dev.145441

Paper Role of cell–cell adhesion complexes in embryonic stem cell biology

Pieters, Tim; Roy, Frans van · 2014 · Journal of Cell Science · DOI

Full title: Role of cell–cell adhesion complexes in embryonic stem cell biology

Authors: Pieters, Tim; Roy, Frans van

Year: 2014

Venue: Journal of Cell Science

DOI: https://doi.org/10.1242/jcs.146720

Paper Epigenetic Regulation of Sensory Axon Regeneration after Spinal Cord Injury

Finelli, Mattéa J.; Wong, Jamie; Zou, Hongyan · 2013 · Journal of Neuroscience · DOI

Full title: Epigenetic Regulation of Sensory Axon Regeneration after Spinal Cord Injury

Authors: Finelli, Mattéa J.; Wong, Jamie; Zou, Hongyan

Year: 2013

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.0589-13.2013

Paper Mammalian Blastema: Possibility and Potentials.

Nam, Juhyeon; Min, Byungkuk; Baek, Areum et al. · 2025 · International journal of stem cells · DOI

Full title: Mammalian Blastema: Possibility and Potentials.

Authors: Nam, Juhyeon; Min, Byungkuk; Baek, Areum; Lee, Sang-Yun; Ha, Jeongmin; Cho, Min Ji; Kim, Janghwan

Year: 2025

Venue: International journal of stem cells

DOI: https://doi.org/10.15283/ijsc24121

Paper The Role of Microenvironment in Preserving the Potency of Adult Porcine Pulmonary Valve Stem Cells In Vitro.

Chalajour, Fariba; Siyahian, Arpi; Hanley, Frank L · 2018 · International journal of stem cells · DOI

Full title: The Role of Microenvironment in Preserving the Potency of Adult Porcine Pulmonary Valve Stem Cells In Vitro.

Authors: Chalajour, Fariba; Siyahian, Arpi; Hanley, Frank L

Year: 2018

Venue: International journal of stem cells

DOI: https://doi.org/10.15283/ijsc18020

Paper Role of transcription factors in the transdifferentiation of pancreatic islet cells

Meulen, Talitha van der; Huising, Mark O. · 2015 · Journal of Molecular Endocrinology · DOI

Full title: Role of transcription factors in the transdifferentiation of pancreatic islet cells

Authors: Meulen, Talitha van der; Huising, Mark O.

Year: 2015

Venue: Journal of Molecular Endocrinology

DOI: https://doi.org/10.1530/jme-14-0290

Paper G9a and Jhdm2a Regulate Embryonic Stem Cell Fusion-Induced Reprogramming of Adult Neural Stem Cells

Dengke, K.; Chiang, Jason; Ponnusamy, Karthikeyan et al. · 2008 · Stem Cells · DOI

Full title: G9a and Jhdm2a Regulate Embryonic Stem Cell Fusion-Induced Reprogramming of Adult Neural Stem Cells

Authors: Dengke, K.; Chiang, Jason; Ponnusamy, Karthikeyan; Ming, Guo‐li; Song, Hongjun

Year: 2008

Venue: Stem Cells

DOI: https://doi.org/10.1634/stemcells.2008-0388

Paper Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis.

Zhang, Chenchen; Bai, Yuerong; Yin, Qimeng et al. · 2026 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis.

Authors: Zhang, Chenchen; Bai, Yuerong; Yin, Qimeng; Li, Jiahao; Huang, Kun; Qiu, Min

Year: 2026

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2025.114569

Paper Research of in vivo reprogramming toward clinical applications in regenerative medicine: A concise review.

Nakatsukasa, Yoshihiko; Yamada, Yosuke; Yamada, Yasuhiro · 2025 · Regenerative therapy · DOI

Full title: Research of in vivo reprogramming toward clinical applications in regenerative medicine: A concise review.

Authors: Nakatsukasa, Yoshihiko; Yamada, Yosuke; Yamada, Yasuhiro

Year: 2025

Venue: Regenerative therapy

DOI: https://doi.org/10.1016/j.reth.2024.11.008

Paper Anti-aging strategies and ex vivo organ rejuvenation.

Haoui, Monika; Reddy, Pradeep; Izpisua Belmonte, Juan Carlos · 2026 · Cell stem cell · DOI

Full title: Anti-aging strategies and ex vivo organ rejuvenation.

Authors: Haoui, Monika; Reddy, Pradeep; Izpisua Belmonte, Juan Carlos

Year: 2026

Venue: Cell stem cell

DOI: https://doi.org/10.1016/j.stem.2025.12.011

Paper Cognitive rejuvenation through partial reprogramming of engram cells.

Berdugo-Vega, Gabriel; Sierra, Cesar; Astori, Simone et al. · 2026 · Neuron · DOI

Full title: Cognitive rejuvenation through partial reprogramming of engram cells.

Authors: Berdugo-Vega, Gabriel; Sierra, Cesar; Astori, Simone; Calati, Veronika; Orsat, Jules; Scoglio, Marianne Julie; Sandi, Carmen; Gräff, Johannes

Year: 2026

Venue: Neuron

DOI: https://doi.org/10.1016/j.neuron.2025.11.028

Paper Partial reprogramming by cyclical overexpression of Yamanaka factors improves pathological phenotypes of tauopathy mouse model of human Alzheimer's disease.

Antón-Fernández, Alejandro; Ruiz de Alegría, Álvaro; Mariscal-Casero, Ana et al. · 2025 · Progress in neurobiology · DOI

Full title: Partial reprogramming by cyclical overexpression of Yamanaka factors improves pathological phenotypes of tauopathy mouse model of human Alzheimer's disease.

Authors: Antón-Fernández, Alejandro; Ruiz de Alegría, Álvaro; Mariscal-Casero, Ana; Roldán-Lázaro, Marta; Peinado-Cauchola, Rocío; Ávila, Jesús; Hernández, Félix

Year: 2025

Venue: Progress in neurobiology

DOI: https://doi.org/10.1016/j.pneurobio.2025.102743

Paper In vivo partial reprogramming by bacteria promotes adult liver organ growth without fibrosis and tumorigenesis.

Hess, Samuel; Kendall, Timothy J; Pena, Maria et al. · 2022 · Cell reports. Medicine · DOI

Full title: In vivo partial reprogramming by bacteria promotes adult liver organ growth without fibrosis and tumorigenesis.

Authors: Hess, Samuel; Kendall, Timothy J; Pena, Maria; Yamane, Keitaro; Soong, Daniel; Adams, Linda; Truman, Richard; Rambukkana, Anura

Year: 2022

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2022.100820

Paper Deconstructing networks of p53-mediated tumor suppression in vivo

Kaiser, Alyssa M.; Attardi, Laura D. · 2017 · Cell Death and Differentiation · DOI

Full title: Deconstructing networks of p53-mediated tumor suppression in vivo

Authors: Kaiser, Alyssa M.; Attardi, Laura D.

Year: 2017

Venue: Cell Death and Differentiation

DOI: https://doi.org/10.1038/cdd.2017.171

Paper Two-factor reprogramming of somatic cells to pluripotent stem cells reveals partial functional redundancy of Sox2 and Klf4.

Nemajerova, A; Kim, S Y; Petrenko, O et al. · 2012 · Cell death and differentiation · DOI

Full title: Two-factor reprogramming of somatic cells to pluripotent stem cells reveals partial functional redundancy of Sox2 and Klf4.

Authors: Nemajerova, A; Kim, S Y; Petrenko, O; Moll, U M

Year: 2012

Venue: Cell death and differentiation

DOI: https://doi.org/10.1038/cdd.2012.45

Paper Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells

Wang, Fang; Yin, Yu; Ye, Xiaoying et al. · 2011 · Cell Research · DOI

Full title: Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells

Authors: Wang, Fang; Yin, Yu; Ye, Xiaoying; Liu, Kai; Zhu, Haiying; Wang, Lingling; Chiourea, Maria; Okuka, Maja; Ji, Guangzhen; Dan, Jiameng; Zuo, Bingfeng; Li, Minshu; Zhang, Qian; Liu, Na; Chen, Lingyi; Pan, Xinghua; Gagos, Sarantis; Keefe, David L.; Liu, Lin

Year: 2011

Venue: Cell Research

DOI: https://doi.org/10.1038/cr.2011.201

Paper Pluripotency: partial reprogramming induces cancer.

Alderton, Gemma K · 2014 · Nature reviews. Cancer · DOI

Full title: Pluripotency: partial reprogramming induces cancer.

Authors: Alderton, Gemma K

Year: 2014

Venue: Nature reviews. Cancer

DOI: https://doi.org/10.1038/nrc3713

Paper Senescence and cancer — role and therapeutic opportunities

Schmitt, Clemens A.; Wang, Boshi; Demaria, Marco · 2022 · Nature Reviews Clinical Oncology · DOI

Full title: Senescence and cancer — role and therapeutic opportunities

Authors: Schmitt, Clemens A.; Wang, Boshi; Demaria, Marco

Year: 2022

Venue: Nature Reviews Clinical Oncology

DOI: https://doi.org/10.1038/s41571-022-00668-4

Paper Drug delivery systems for RNA therapeutics

Paunovska, Kalina; Loughrey, David; Dahlman, James E. · 2022 · Nature Reviews Genetics · DOI

Full title: Drug delivery systems for RNA therapeutics

Authors: Paunovska, Kalina; Loughrey, David; Dahlman, James E.

Year: 2022

Venue: Nature Reviews Genetics

DOI: https://doi.org/10.1038/s41576-021-00439-4

Paper Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

Dilliard, Sean A.; Siegwart, Daniel J. · 2023 · Nature Reviews Materials · DOI

Full title: Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

Authors: Dilliard, Sean A.; Siegwart, Daniel J.

Year: 2023

Venue: Nature Reviews Materials

DOI: https://doi.org/10.1038/s41578-022-00529-7

Paper RNA delivery by extracellular vesicles in mammalian cells and its applications

O’Brien, Killian P.; Breyne, Koen; Ughetto, Stefano et al. · 2020 · Nature Reviews Molecular Cell Biology · DOI

Full title: RNA delivery by extracellular vesicles in mammalian cells and its applications

Authors: O’Brien, Killian P.; Breyne, Koen; Ughetto, Stefano; Laurent, Louise C.; Breakefield, Xandra O.

Year: 2020

Venue: Nature Reviews Molecular Cell Biology

DOI: https://doi.org/10.1038/s41580-020-0251-y

Paper Genetic determinants and epigenetic effects of pioneer-factor occupancy

Donaghey, Julie; Thakurela, Sudhir; Charlton, Jocelyn et al. · 2018 · Nature Genetics · DOI

Full title: Genetic determinants and epigenetic effects of pioneer-factor occupancy

Authors: Donaghey, Julie; Thakurela, Sudhir; Charlton, Jocelyn; Chen, Jennifer; Smith, Zachary D.; Gu, Hongcang; Pop, Ramona; Clement, Kendell; Stamenova, Elena K.; Karnik, Rahul; Kelley, David R.; Gifford, Casey A.; Cacchiarelli, Davide; Rinn, John L.; Gnirke, Andreas; Ziller, Michael J.; Meissner, Alexander

Year: 2018

Venue: Nature Genetics

DOI: https://doi.org/10.1038/s41588-017-0034-3

Paper In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.

Browder, Kristen C; Reddy, Pradeep; Yamamoto, Mako et al. · 2022 · Nature aging · DOI

Full title: In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.

Authors: Browder, Kristen C; Reddy, Pradeep; Yamamoto, Mako; Haghani, Amin; Guillen, Isabel Guillen; Sahu, Sanjeeb; Wang, Chao; Luque, Yosu; Prieto, Javier; Shi, Lei; Shojima, Kensaku; Hishida, Tomoaki; Lai, Zijuan; Li, Qingling; Choudhury, Feroza K; Wong, Weng R; Liang, Yuxin; Sangaraju, Dewakar; Sandoval, Wendy; Esteban, Concepcion Rodriguez; Delicado, Estrella Nuñez; Garcia, Pedro Guillen; Pawlak, Michal; Vander Heiden, Jason A; Horvath, Steve; Jasper, Heinrich; Izpisua Belmonte, Juan Carlos

Year: 2022

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-022-00183-2

Paper Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell, Wayne; Goeminne, Ludger J E; Tyshkovskiy, Alexander et al. · 2024 · eLife · DOI

Full title: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/eLife.90579

Paper Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell, Wayne; Goeminne, Ludger J E; Tyshkovskiy, Alexander et al. · 2024 · eLife · DOI

Full title: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/eLife.90579

Paper Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Mitchell, Wayne; Goeminne, Ludger J E; Tyshkovskiy, Alexander et al. · 2024 · eLife · DOI

Full title: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/eLife.90579

Paper Restoration of neuronal progenitors by partial reprogramming in the aged neurogenic niche.

Xu, Lucy; Ramirez-Matias, Julliana; Hauptschein, Max et al. · 2024 · Nature aging · DOI

Full title: Restoration of neuronal progenitors by partial reprogramming in the aged neurogenic niche.

Authors: Xu, Lucy; Ramirez-Matias, Julliana; Hauptschein, Max; Sun, Eric D; Lunger, Judith C; Buckley, Matthew T; Brunet, Anne

Year: 2024

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-024-00594-3

Paper Partial reprogramming of the mammalian brain.

Asmussen, Niels C; Schafer, Marissa J · 2024 · Nature aging · DOI

Full title: Partial reprogramming of the mammalian brain.

Authors: Asmussen, Niels C; Schafer, Marissa J

Year: 2024

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-024-00596-1

Paper Fibroblast rejuvenation by mechanical reprogramming and redifferentiation

Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim et al. · 2020 · Proceedings of the National Academy of Sciences · DOI

Full title: Fibroblast rejuvenation by mechanical reprogramming and redifferentiation

Authors: Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim; Bharti, Aradhana; Mitra, Aninda; Shivashankar, G. V.

Year: 2020

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1911497117

Paper Precision Reprogramming-Restoring Function to Aged Cells.

Jain, Arjun; Hosokawa, Yuuki; Joseph, Kevin · 2025 · Cellular reprogramming · DOI

Full title: Precision Reprogramming-Restoring Function to Aged Cells.

Authors: Jain, Arjun; Hosokawa, Yuuki; Joseph, Kevin

Year: 2025

Venue: Cellular reprogramming

DOI: https://doi.org/10.1089/cell.2025.0018

Paper Rejuvenation of Cardiac Tissue Developed from Reprogrammed Aged Somatic Cells.

Cheng, Zhao; Peng, Hong-Ling; Zhang, Rong et al. · 2017 · Rejuvenation research · DOI

Full title: Rejuvenation of Cardiac Tissue Developed from Reprogrammed Aged Somatic Cells.

Authors: Cheng, Zhao; Peng, Hong-Ling; Zhang, Rong; Fu, Xian-Ming; Zhang, Guang-Sen

Year: 2017

Venue: Rejuvenation research

DOI: https://doi.org/10.1089/rej.2017.1930

Paper Gene Therapy-Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice.

Macip, Carolina Cano; Hasan, Rokib; Hoznek, Victoria et al. · 2024 · Cellular reprogramming · DOI

Full title: Gene Therapy-Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice.

Authors: Macip, Carolina Cano; Hasan, Rokib; Hoznek, Victoria; Kim, Jihyun; Lu, Yuancheng Ryan; Metzger, Louis E; Sethna, Saumil; Davidsohn, Noah

Year: 2024

Venue: Cellular reprogramming

DOI: https://doi.org/10.1089/cell.2023.0072

Paper p53 is balancing development, differentiation and de-differentiation to assure cancer prevention

Molchadsky, Alina; Rivlin, Noa; Brosh, Ran et al. · 2010 · Carcinogenesis · DOI

Full title: p53 is balancing development, differentiation and de-differentiation to assure cancer prevention

Authors: Molchadsky, Alina; Rivlin, Noa; Brosh, Ran; Rotter, Varda; Sarig, Rachel

Year: 2010

Venue: Carcinogenesis

DOI: https://doi.org/10.1093/carcin/bgq101

Paper The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy.

Rizzo, Joseph F; Shah, Madhura P; Krasniqi, Drenushe et al. · 2024 · Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · DOI

Full title: The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy.

Authors: Rizzo, Joseph F; Shah, Madhura P; Krasniqi, Drenushe; Lu, Yuancheng Ryan; Sinclair, David A; Ksander, Bruce R

Year: 2024

Venue: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

DOI: https://doi.org/10.1097/WNO.0000000000002041

Paper Isolation, Characterization, Gene Modification, and Nuclear Reprogramming of Porcine Mesenchymal Stem Cells1

Bosch, Pablo; Pratt, Scott L.; Stice, Steven L. · 2005 · Biology of Reproduction · DOI

Full title: Isolation, Characterization, Gene Modification, and Nuclear Reprogramming of Porcine Mesenchymal Stem Cells1

Authors: Bosch, Pablo; Pratt, Scott L.; Stice, Steven L.

Year: 2005

Venue: Biology of Reproduction

DOI: https://doi.org/10.1095/biolreprod.105.045138

Paper Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers

Seisenberger, Stefanie; Peat, Julian R.; Hore, Timothy A. et al. · 2012 · Philosophical Transactions of the Royal Society B Biological Sciences · DOI

Full title: Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers

Authors: Seisenberger, Stefanie; Peat, Julian R.; Hore, Timothy A.; Santos, Fátima; Dean, Wendy; Reik, Wolf

Year: 2012

Venue: Philosophical Transactions of the Royal Society B Biological Sciences

DOI: https://doi.org/10.1098/rstb.2011.0330

Paper Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc et al. · 2022 · Aging Cell · DOI

Full title: Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Authors: Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc; Urdinguio, Rocío G.; Berenguer, Antonio; Aguilera, Mònica; Durand, Sylvère; Aprahamian, Fanny; Nirmalathasan, Nitharsshini; Abad, María; Martin‐Herranz, Daniel E.; Attolini, Camille Stephan‐Otto; Prats, Neus; Kroemer, Guido; Fraga, Mario F.; Reik, Wolf; Serrano, Manuel

Year: 2022

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13578

Paper Transcriptional activation of endogenous Oct4 via the CRISPR / dCas9 activator ameliorates Hutchinson‐Gilford progeria syndrome in mice

Kim, Junyeop; Hwang, Yerim; Kim, Sumin et al. · 2023 · Aging Cell · DOI

Full title: Transcriptional activation of endogenous Oct4 via the CRISPR / dCas9 activator ameliorates Hutchinson‐Gilford progeria syndrome in mice

Authors: Kim, Junyeop; Hwang, Yerim; Kim, Sumin; Chang, Yu‐Jung; Kim, Yun-Kyung; Kwon, Youngeun; Kim, Jongpil; Kim, Jongpil; Kim, Jongpil

Year: 2023

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13825

Paper Senescence promotes in vivo reprogramming through p16 INK 4a and IL ‐6

Mosteiro, Lluc; Pantoja, Cristina; Martino, Alba De et al. · 2017 · Aging Cell · DOI

Full title: Senescence promotes in vivo reprogramming through p16 INK 4a and IL ‐6

Authors: Mosteiro, Lluc; Pantoja, Cristina; Martino, Alba De; Serrano, Manuel

Year: 2017

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12711

Paper Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity.

Olova, Nelly; Simpson, Daniel J; Marioni, Riccardo E et al. · 2019 · Aging cell · DOI

Full title: Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity.

Authors: Olova, Nelly; Simpson, Daniel J; Marioni, Riccardo E; Chandra, Tamir

Year: 2019

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12877

Paper Partial reprogramming strategy for intervertebral disc rejuvenation by activating energy switch.

Cheng, Feng; Wang, Chenggui; Ji, Yufei et al. · 2022 · Aging cell · DOI

Full title: Partial reprogramming strategy for intervertebral disc rejuvenation by activating energy switch.

Authors: Cheng, Feng; Wang, Chenggui; Ji, Yufei; Yang, Biao; Shu, Jiawei; Shi, Kesi; Wang, Lulu; Wang, Shaoke; Zhang, Yuang; Huang, Xianpeng; Zhou, Xiaopeng; Xia, Kaishun; Liang, Chengzhen; Chen, Qixin; Li, Fangcai

Year: 2022

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13577

Paper Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging.

Vilas, Jéssica M; Carneiro, Carmen; Da Silva-Álvarez, Sabela et al. · 2018 · Aging cell · DOI

Full title: Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging.

Authors: Vilas, Jéssica M; Carneiro, Carmen; Da Silva-Álvarez, Sabela; Ferreirós, Alba; González, Patricia; Gómez, María; Ortega, Sagrario; Serrano, Manuel; García-Caballero, Tomás; González-Barcia, Miguel; Vidal, Anxo; Collado, Manuel

Year: 2018

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12834

Paper Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.

Paine, Patrick T; Nguyen, Ada; Ocampo, Alejandro · 2024 · Aging cell · DOI

Full title: Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.

Authors: Paine, Patrick T; Nguyen, Ada; Ocampo, Alejandro

Year: 2024

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.14039

Paper Hippocampal rejuvenation by a single intracerebral injection of one-carbon metabolites in C57BL6 old wild-type mice.

Antón-Fernández, Alejandro; Cauchola, Rocío Peinado; Hernández, Félix et al. · 2025 · Aging cell · DOI

Full title: Hippocampal rejuvenation by a single intracerebral injection of one-carbon metabolites in C57BL6 old wild-type mice.

Authors: Antón-Fernández, Alejandro; Cauchola, Rocío Peinado; Hernández, Félix; Ávila, Jesús

Year: 2025

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.14365

Paper Primary cardiac sarcomas may develop from resident or bone marrow-derived mesenchymal stem cells: use of immunohistochemistry including CD44 and octamer binding protein 3/4.

Hegyi, Laszlo; Thway, Khin; Fisher, Cyril et al. · 2012 · Histopathology · DOI

Full title: Primary cardiac sarcomas may develop from resident or bone marrow-derived mesenchymal stem cells: use of immunohistochemistry including CD44 and octamer binding protein 3/4.

Authors: Hegyi, Laszlo; Thway, Khin; Fisher, Cyril; Sheppard, Mary N

Year: 2012

Venue: Histopathology

DOI: https://doi.org/10.1111/j.1365-2559.2012.04299.x

Paper Control of cell death and mitochondrial fission by ERK 1/2 MAP kinase signalling

Cook, Simon J.; Stuart, Kate; Gilley, Rebecca et al. · 2017 · FEBS Journal · DOI

Full title: Control of cell death and mitochondrial fission by ERK 1/2 MAP kinase signalling

Authors: Cook, Simon J.; Stuart, Kate; Gilley, Rebecca; Sale, Matthew J.

Year: 2017

Venue: FEBS Journal

DOI: https://doi.org/10.1111/febs.14122

Paper A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.

Jones, Ronald G; Dimet-Wiley, Andrea; Haghani, Amin et al. · 2023 · The Journal of physiology · DOI

Full title: A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.

Authors: Jones, Ronald G; Dimet-Wiley, Andrea; Haghani, Amin; da Silva, Francielly Morena; Brightwell, Camille R; Lim, Seongkyun; Khadgi, Sabin; Wen, Yuan; Dungan, Cory M; Brooke, Robert T; Greene, Nicholas P; Peterson, Charlotte A; McCarthy, John J; Horvath, Steve; Watowich, Stanley J; Fry, Christopher S; Murach, Kevin A

Year: 2023

Venue: The Journal of physiology

DOI: https://doi.org/10.1113/JP283836

Paper Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction.

Kim, Jumee; Kim, Somi; Lee, Seung-Yeon et al. · 2023 · Science advances · DOI

Full title: Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction.

Authors: Kim, Jumee; Kim, Somi; Lee, Seung-Yeon; Jo, Beom-Ki; Oh, Ji-Young; Kwon, Eun-Ji; Kim, Keun-Tae; Adpaikar, Anish Ashok; Kim, Eun-Jung; Jung, Han-Sung; Kim, Hwa-Ryeon; Roe, Jae-Seok; Hong, Chang Pyo; Kim, Jong Kyoung; Koo, Bon-Kyoung; Cha, Hyuk-Jin

Year: 2023

Venue: Science advances

DOI: https://doi.org/10.1126/sciadv.adi8454

Paper Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging.

Sahu, Sanjeeb Kumar; Reddy, Pradeep; Lu, Jinlong et al. · 2024 · Science translational medicine · DOI

Full title: Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging.

Authors: Sahu, Sanjeeb Kumar; Reddy, Pradeep; Lu, Jinlong; Shao, Yanjiao; Wang, Chao; Tsuji, Mako; Delicado, Estrella Nuñez; Rodriguez Esteban, Concepcion; Belmonte, Juan Carlos Izpisua

Year: 2024

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.adg1777

Paper Lineage Plasticity in Cancer Progression and Treatment

Magnen, Clémentine Le; Shen, Michael M.; Abate‐Shen, Cory · 2017 · Annual Review of Cancer Biology · DOI

Full title: Lineage Plasticity in Cancer Progression and Treatment

Authors: Magnen, Clémentine Le; Shen, Michael M.; Abate‐Shen, Cory

Year: 2017

Venue: Annual Review of Cancer Biology

DOI: https://doi.org/10.1146/annurev-cancerbio-030617-050224

Paper Histone H3 Variants and Their Chaperones During Development and Disease: Contributing to Epigenetic Control

Filipescu, Dan; Müller, Sebastian; Almouzni, Geneviève · 2014 · Annual Review of Cell and Developmental Biology · DOI

Full title: Histone H3 Variants and Their Chaperones During Development and Disease: Contributing to Epigenetic Control

Authors: Filipescu, Dan; Müller, Sebastian; Almouzni, Geneviève

Year: 2014

Venue: Annual Review of Cell and Developmental Biology

DOI: https://doi.org/10.1146/annurev-cellbio-100913-013311

Paper Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

Mertens, Jérôme; Reid, Dylan A.; Lau, Shong et al. · 2018 · Annual Review of Genetics · DOI

Full title: Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

Authors: Mertens, Jérôme; Reid, Dylan A.; Lau, Shong; Kim, Yongsung; Gage, Fred H.

Year: 2018

Venue: Annual Review of Genetics

DOI: https://doi.org/10.1146/annurev-genet-120417-031534

Paper Reprogramming Müller Glia to Regenerate Retinal Neurons

Lahne, Manuela; Nagashima, Mikiko; Hyde, David R. et al. · 2020 · Annual Review of Vision Science · DOI

Full title: Reprogramming Müller Glia to Regenerate Retinal Neurons

Authors: Lahne, Manuela; Nagashima, Mikiko; Hyde, David R.; Hitchcock, Peter F.

Year: 2020

Venue: Annual Review of Vision Science

DOI: https://doi.org/10.1146/annurev-vision-121219-081808

Paper The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

Yamamoto, Masayuki; Kensler, Thomas W.; Motohashi, Hozumi · 2018 · Physiological Reviews · DOI

Full title: The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

Authors: Yamamoto, Masayuki; Kensler, Thomas W.; Motohashi, Hozumi

Year: 2018

Venue: Physiological Reviews

DOI: https://doi.org/10.1152/physrev.00023.2017

Paper Adipose-Derived Stem Cells in Tissue Regeneration: A Review

Zuk, Patricia A. · 2013 · ISRN Stem Cells · DOI

Full title: Adipose-Derived Stem Cells in Tissue Regeneration: A Review

Authors: Zuk, Patricia A.

Year: 2013

Venue: ISRN Stem Cells

DOI: https://doi.org/10.1155/2013/713959

Paper Effect on Multipotency and Phenotypic Transition of Unrestricted Somatic Stem Cells from Human Umbilical Cord Blood after Treatment with Epigenetic Agents.

Ghanjati, Foued; Santourlidis, Simeon · 2016 · Stem cells international · DOI

Full title: Effect on Multipotency and Phenotypic Transition of Unrestricted Somatic Stem Cells from Human Umbilical Cord Blood after Treatment with Epigenetic Agents.

Authors: Ghanjati, Foued; Santourlidis, Simeon

Year: 2016

Venue: Stem cells international

DOI: https://doi.org/10.1155/2016/7643218

Paper Progress in the Reprogramming of Somatic Cells

Ma, Tianhua; Xie, Min; Laurent, Timothy et al. · 2013 · Circulation Research · DOI

Full title: Progress in the Reprogramming of Somatic Cells

Authors: Ma, Tianhua; Xie, Min; Laurent, Timothy; Ding, Sheng

Year: 2013

Venue: Circulation Research

DOI: https://doi.org/10.1161/circresaha.111.249235

Paper Single-Short Partial Reprogramming of the Endothelial Cells Decreases Blood Pressure via Attenuation of EndMT in Hypertensive Mice.

Pernomian, Laena; Waigi, Emily W; Nguyen, Vi et al. · 2025 · Circulation research · DOI

Full title: Single-Short Partial Reprogramming of the Endothelial Cells Decreases Blood Pressure via Attenuation of EndMT in Hypertensive Mice.

Authors: Pernomian, Laena; Waigi, Emily W; Nguyen, Vi; Mohammed, Ahmed D; Costa, Tiago J; Fontes, Milene T; Kubinak, Jason L; Aitken, Andrew V; Biancardi, Vinicia Campana; Gleason, Kamryn; Shazly, Tarek; Sinclair, David A; McCarthy, Cameron G; Wang, Yunguan; Tan, Wenbin; Wenceslau, Camilla Ferreira

Year: 2025

Venue: Circulation research

DOI: https://doi.org/10.1161/CIRCRESAHA.124.324909

Paper Long Live Partial Reprogramming.

Marión, Rosa M; Blasco, Maria A · 2017 · Circulation research · DOI

Full title: Long Live Partial Reprogramming.

Authors: Marión, Rosa M; Blasco, Maria A

Year: 2017

Venue: Circulation research

DOI: https://doi.org/10.1161/CIRCRESAHA.117.310594

Paper De novo generation of HSCs from somatic and pluripotent stem cell sources

Vo, Linda T.; Daley, George Q. · 2015 · Blood · DOI

Full title: De novo generation of HSCs from somatic and pluripotent stem cell sources

Authors: Vo, Linda T.; Daley, George Q.

Year: 2015

Venue: Blood

DOI: https://doi.org/10.1182/blood-2014-10-570234

Thesis Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities

Galkin, Fedor; Mamoshina, Polina; Aliper, Alex et al. · 2020 · University of Liverpool · DOI

Full title: Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities

Authors: Galkin, Fedor; Mamoshina, Polina; Aliper, Alex; de Magalhaes, Joao Pedro; Gladyshev, Vadim N; Zhavoronkov, Alex

Year: 2020

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3084677

Thesis Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

Gascón, Sergio; Murenu, Elisa; Masserdotti, Giacomo et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

Authors: Gascón, Sergio;Murenu, Elisa;Masserdotti, Giacomo;Ortega, Felipe;Russo, Gianluca L.;Petrik, David;Deshpande, Aditi;Heinrich, Christophe;Karow, Marisa;Robertson, Stephen P.;Schroeder, Timm;Beckers, Johannes;Irmler, Martin;Berndt, Carsten;Angeli, José P. Friedmann;Conrad, Marcus;Berninger, Benedikt;Götz, Magdalena

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1321033

Thesis Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector.

Merkl, Claudia; Saalfrank, Anja; Riesen, Nathalie et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector.

Authors: Merkl, Claudia;Saalfrank, Anja;Riesen, Nathalie;Kühn, Ralf;Pertek, Anna;Eser, Stefan;Hardt, Markus Sebastian;Kind, Alexander;Saur, Dieter;Wurst, Wolfgang;Iglesias, Antonio;Schnieke, Angelika

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1211164

Thesis Systems Biology Of Gene Regulation Across Scales: From Single Molecules To Cellular Identities

Mellis, Ian Alexander · 2023 · University of Pennsylvania · DOI

Full title: Systems Biology Of Gene Regulation Across Scales: From Single Molecules To Cellular Identities

Authors: Mellis, Ian Alexander

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/30634

Thesis The transcriptional landscape of age in human peripheral blood.

Peters, Marjolein J; Joehanes, Roby; Pilling, Luke C et al. · 2015 · Technical University of Munich (TUM) · DOI

Full title: The transcriptional landscape of age in human peripheral blood.

Authors: Peters, Marjolein J;Joehanes, Roby;Pilling, Luke C;Schurmann, Claudia;Conneely, Karen N;Powell, Joseph;Reinmaa, Eva;Sutphin, George L;Zhernakova, Alexandra;Schramm, Katharina;Wilson, Yana A;Kobes, Sayuko;Tukiainen, Taru;Ramos, Yolande F;Göring, Harald H H;Fornage, Myriam;Liu, Yongmei;Gharib, Sina A;Stranger, Barbara E;De Jager, Philip L;Aviv, Abraham;Levy, Daniel;Murabito, Joanne M;Munson, Peter J;Huan, Tianxiao;Hofman, Albert;Uitterlinden, Andre G;Rivadeneira, Fernando;van Rooij, Jeroen;Stolk, Lisette;Broer, Linda;Verbiest, Michael M P J;Jhamai, Mila;Arp, Pascal;Metspalu, Andres;Tserel, Liina;Milani, Lili;Samani, Nilesh J;Peterson, Pärt;Kasela, Silva;Codd, Veryan;Peters, Annette;Ward-Caviness, Cavin K;Herder, Christian;Waldenberger, Melanie;Roden, Michael;Singmann, Paula;Zeilinger, Sonja;Illig, Thomas;Homuth, Georg;Grabe, Hans-Jörgen;Völzke, Henry;Steil, Leif;Kocher, Thomas;Murray, Anna;Melzer, David;Yaghootkar, Hanieh;Bandinelli, Stefania;Moses, Eric K;Kent, Jack W;Curran, Joanne E;Johnson, Matthew P;Williams-Blangero, Sarah;Westra, Harm-Jan;McRae, Allan F;Smith, Jennifer A;Kardia, Sharon L R;Hovatta, Iiris;Perola, Markus;Ripatti, Samuli;Salomaa, Veikko;Henders, Anjali K;Martin, Nicholas G;Smith, Alicia K;Mehta, Divya;Binder, Elisabeth B;Nylocks, K Maria;Kennedy, Elizabeth M;Klengel, Torsten;Ding, Jingzhong;Suchy-Dicey, Astrid M;Enquobahrie, Daniel A;Brody, Jennifer;Rotter, Jerome I;Chen, Yii-Der I;Houwing-Duistermaat, Jeanine;Kloppenburg, Margreet;Slagboom, P Eline;Helmer, Quinta;den Hollander, Wouter;Bean, Shannon;Raj, Towfique;Bakhshi, Noman;Wang, Qiao Ping;Oyston, Lisa J;Psaty, Bruce M;Tracy, Russell P;Montgomery, Grant W;Turner, Stephen T;Blangero, John;Meulenbelt, Ingrid;Ressler, Kerry J;Yang, Jian;Franke, Lude;Kettunen, Johannes;Visscher, Peter M;Neely, G Gregory;Korstanje, Ron;Hanson, Robert L;Prokisch, Holger;Ferrucci, Luigi;Esko, Tõnu;Teumer, Alexander;van Meurs, Joyce B J;Johnson, Andrew D

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1321810

Thesis Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy

Theodorou, M.; Rauser, B.; Zhang, J. et al. · 2015 · Technical University of Munich (TUM) · DOI

Full title: Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy

Authors: Theodorou, M.;Rauser, B.;Zhang, J.;Prakash, N.;Wurst, W.;Schick, J. A.

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1431292

Thesis The Maintenance of Age in Reprogrammed Human Neurons

Huh, Christine Jean · 2016 · Washington University in St. Louis · DOI

Full title: The Maintenance of Age in Reprogrammed Human Neurons

Authors: Huh, Christine Jean

Year: 2016

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/994

Thesis Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

Gascón, S.; Murenu, E.; Masserdotti, G. et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

Authors: Gascón, S.;Murenu, E.;Masserdotti, G.;Ortega, F.;Russo, G. L.;Petrik, D.;Deshpande, A.;Heinrich, C.;Karow, M.;Robertson, S. P.;Schroeder, T.;Beckers, J.;Irmler, M.;Berndt, C.;Angeli, J. P.;Conrad, M.;Berninger, B.;Götz, M.

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1431007

Thesis Brain Enriched microRNAs Open the Neurogenic Potential of Adult Human Fibroblasts

Abernathy, Daniel Gene · 2017 · Washington University in St. Louis · DOI

Full title: Brain Enriched microRNAs Open the Neurogenic Potential of Adult Human Fibroblasts

Authors: Abernathy, Daniel Gene

Year: 2017

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/1216

Thesis Dissecting the role of chromatin remodeling in direct lineage reprogramming

Jindal, Kunal · 2024 · Washington University in St. Louis · DOI

Full title: Dissecting the role of chromatin remodeling in direct lineage reprogramming

Authors: Jindal, Kunal

Year: 2024

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/3030

Thesis Identification and successful negotiation of a metabolic checkpoint in direct neuronal repogramming.

Gascón, S.; Murenu, E.; Masserdotti, G. et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: Identification and successful negotiation of a metabolic checkpoint in direct neuronal repogramming.

Authors: Gascón, S. ; Murenu, E. ; Masserdotti, G. ; Ortega, F. ; Russo, G.L. ; Petrik, D. ; Deshpande, A. ; Heinrich, C. ; Karow, M. ; Robertson, S.P. ; Schroeder, T. ; Beckers, J. ; Irmler, M. ; Berndt, C. ; Friedmann Angeli, J.P.F. ; Conrad, M. ; Berninger, B. ; Götz, M.

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1425948

Thesis Single-Cell Analysis of Clonal and Transcriptional Dynamics During Direct Reprogramming

Biddy, Brent · 2025 · Washington University in St. Louis · DOI

Full title: Single-Cell Analysis of Clonal and Transcriptional Dynamics During Direct Reprogramming

Authors: Biddy, Brent

Year: 2025

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/3549

Thesis A multi-omics approach to understand mesenchymal stem cell ageing

Jiang, C · 2019 · University of Oxford - ORA · DOI

Full title: A multi-omics approach to understand mesenchymal stem cell ageing

Authors: Jiang, C

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:c76c4df8-51db-4c3c-953c-db4d898f698e

Thesis Generation of diverse neural cell types through direct conversion

Petersen, Gayle F; Strappe, Padraig M · 2016 · Charles Sturt University - Research Output · DOI

Full title: Generation of diverse neural cell types through direct conversion

Authors: Petersen, Gayle F; Strappe, Padraig M

Year: 2016

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/bbf47945-849b-44de-bd47-5dd83a56caef

Thesis Are we there yet? How and when specific biotechnologies will improve human health

O'Day, Elizabeth; Hosta-Rigau, Leticia; id_orcid 0000-0001-8177-4806 et al. · 2019 · Technical University of Denmark (DTU) · DOI

Full title: Are we there yet? How and when specific biotechnologies will improve human health

Authors: O'Day, Elizabeth; Hosta-Rigau, Leticia; id_orcid 0000-0001-8177-4806; Oyarzún, Diego A.; Okano, Hideyuki; de Lorenzo, Víctor; von Kameke, Conrad; Alsafar, Habiba; Cao, Cong; Chen, Guo-Qiang; Ji, Weizhi; Roberts, Richard J.; Ronaghi, Mostafa; Yeung, Karen; Zhang, Feng; Lee, Sang Yup

Year: 2019

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/060dd164-6423-4feb-8c67-41318960300a

Thesis Enhancing the Articular Phenotype of Dedifferentiated Equine Chondrocytes by Expression of Pluripotency Factors

Gurusinghe, S; id_orcid 0000-0001-5779-3468; Strappe, P · 2015 · Charles Sturt University - Research Output · DOI

Full title: Enhancing the Articular Phenotype of Dedifferentiated Equine Chondrocytes by Expression of Pluripotency Factors

Authors: Gurusinghe, S; id_orcid 0000-0001-5779-3468; Strappe, P

Year: 2015

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/9ccb7aa7-e47a-4129-bf02-fbb851426d92

Thesis Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

Xiong, Kai; Zhou, Yan; Hyttel, Poul et al. · 2016 · University of Copenhagen · DOI

Full title: Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

Authors: Xiong, Kai; Zhou, Yan; Hyttel, Poul; Bolund, Lars; Freude, Kristine; Luo, Yonglun

Year: 2016

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/519138d0-655c-4fd0-8a44-dd6e3ea6610f

Thesis Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage

Rasmussen, Mikkel Aabech; Holst, Bjørn; Tümer, Zeynep et al. · 2014 · University of Copenhagen · DOI

Full title: Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage

Authors: Rasmussen, Mikkel Aabech; Holst, Bjørn; Tümer, Zeynep; Johnsen, Mads G.; Zhou, Shuling; Stummann, Tina C.; Hyttel, Poul; Clausen, Christian

Year: 2014

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/923465fa-a077-4c72-ba10-9ff9d5999c00

Thesis Suppression of dedifferentiation and hypertrophy in canine chondrocytes through lentiviral vector expression of Sox9 and induced pluripotency stem cell factors

Gurusinghe, Saliya; id_orcid 0000-0001-5779-3468; Young, Peter et al. · 2015 · Charles Sturt University - Research Output · DOI

Full title: Suppression of dedifferentiation and hypertrophy in canine chondrocytes through lentiviral vector expression of Sox9 and induced pluripotency stem cell factors

Authors: Gurusinghe, Saliya; id_orcid 0000-0001-5779-3468; Young, Peter; Michelsen, Jacob; Strappe, Padraig

Year: 2015

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/a49b0ada-c252-448a-b2e3-87d5adb06df1

Thesis Are we there yet? How and when specific biotechnologies will improve human health

O'Day, Elizabeth; Hosta-Rigau, Leticia; id_orcid 0000-0001-8177-4806 et al. · 2019 · Technical University of Denmark (DTU) · DOI

Full title: Are we there yet? How and when specific biotechnologies will improve human health

Year: 2019

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/060dd164-6423-4feb-8c67-41318960300a

Thesis Overexpression of PGC-1α in aging muscle enhances a subset of young-like molecular patterns

Garcia, Sofia; Nissanka, Nadee; Mareco, Edson A. et al. · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Overexpression of PGC-1α in aging muscle enhances a subset of young-like molecular patterns

Authors: Garcia, Sofia; Nissanka, Nadee; Mareco, Edson A.; Rossi, Susana; Peralta, Susana; Diaz, Francisca; Rotundo, Richard L.; Carvalho, Robson F. [UNESP]; Moraes, Carlos T.

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1111/acel.12707

Thesis Artificial intelligence for aging and longevity research:Recent advances and perspectives

Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin et al. · 2019 · University of Copenhagen · DOI

Full title: Artificial intelligence for aging and longevity research:Recent advances and perspectives

Authors: Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin; Scheibye-Knudsen, Morten; Moskalev, Alexey; Aliper, Alex

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/743e08c3-8932-4394-85df-3f7c159b12f2

Thesis Generation of diverse neural cell types through direct conversion

Petersen, Gayle F; Strappe, Padraig M · 2016 · Charles Sturt University - Research Output · DOI

Full title: Generation of diverse neural cell types through direct conversion

Authors: Petersen, Gayle F; Strappe, Padraig M

Year: 2016

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/bbf47945-849b-44de-bd47-5dd83a56caef

Thesis Direct reprogramming of murine fibroblasts to blood

Florkowska, Magdalena · 2016 · University of Manchester · DOI

Full title: Direct reprogramming of murine fibroblasts to blood

Authors: Florkowska, Magdalena

Year: 2016

Venue: University of Manchester

DOI: https://research.manchester.ac.uk/en/studentTheses/4fb99877-965f-41b7-a3d2-5c8ba198d631

Thesis Aging and drug discovery

Bakula, Daniela; Aliper, Alexander M.; Mamoshina, Polina et al. · 2018 · University of Copenhagen · DOI

Full title: Aging and drug discovery

Authors: Bakula, Daniela; Aliper, Alexander M.; Mamoshina, Polina; Petr, Michael A.; Teklu, Amanuel; Baur, Joseph A.; Campisi, Judith; Ewald, Collin Y.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Kovalchuk, Olga; Lamming, Dudley W.; Luijsterburg, Martijn S.; Martín-Montalvo, Alejandro; Maudsley, Stuart; Mkrtchyan, Garik V.; Moskalev, Alexey; Jay Olshansky, S.; Ozerov, Ivan V.; Pickett, Alexander; Ristow, Michael; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2018

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/482cf743-9684-469f-95cf-421b51dafa33

Thesis Protecting the Aging Genome

Petr, Michael A.; Tulika, Tulika; Carmona-Marin, Lina M. et al. · 2020 · University of Copenhagen · DOI

Full title: Protecting the Aging Genome

Authors: Petr, Michael A.; Tulika, Tulika; Carmona-Marin, Lina M.; Scheibye-Knudsen, Morten

Year: 2020

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/d4be44e0-f589-4bb4-8499-208822c5b344

Thesis Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

Wahlestedt, Martin; Erlandsson, Eva; Kristiansen, Trine et al. · 2017 · University of Copenhagen · DOI

Full title: Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

Authors: Wahlestedt, Martin; Erlandsson, Eva; Kristiansen, Trine; Lu, Rong; Brakebusch, Cord Herbert; Weissman, Irving L; Yuan, Joan; Martin-Gonzalez, Javier; Bryder, David

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/a1909770-f175-48f1-abc8-4028c88ff8ec

Thesis Interventions for age-related diseases:Shifting the paradigm

Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra et al. · 2016 · University of Copenhagen · DOI

Full title: Interventions for age-related diseases:Shifting the paradigm

Authors: Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra; Lopez-Contreras, Andres; Henriques, Catarina M; Selman, Colin; Ferreiro, Elisabete; Gonos, Efstathios S; Trejo, José Luis; Misra, Juhi; Rasmussen, Lene Juel; Xapelli, Sara; Ellam, Timothy; Bellantuono, Ilaria

Year: 2016

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/aa40080c-5965-4caf-93fb-88e42e79ce83

Thesis Induced pluripotent stem cells throughout the animal kingdom:Availability and applications

Pessôa, Laís Vicari de Figueiredo; Bressan, Fabiana Fernandes; Freude, Kristine Karla · 2019 · University of Copenhagen · DOI

Full title: Induced pluripotent stem cells throughout the animal kingdom:Availability and applications

Authors: Pessôa, Laís Vicari de Figueiredo; Bressan, Fabiana Fernandes; Freude, Kristine Karla

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/a577dc77-eafc-4e45-957c-d7f9e3e64859

Thesis Latest advances in aging research and drug discovery

Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano et al. · 2019 · University of Copenhagen · DOI

Full title: Latest advances in aging research and drug discovery

Authors: Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano; Antebi, Adam; Barzilai, Nir; Bittner, Martin Immanuel; Jensen, Martin Borch; Calkhoven, Cornelis F.; Chen, Danica; de Grey, Aubrey D.N.J.; Feige, Jerome N.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Golato, Tyler; Gudkov, Andrei V.; Hoppe, Thorsten; Kaeberlein, Matt; Katajisto, Pekka; Kennedy, Brian K.; Lal, Unmesh; Martin-Villalba, Ana; Moskalev, Alexey A.; Ozerov, Ivan; Petr, Michael A.; Reason; Rubinsztein, David C.; Tyshkovskiy, Alexander; Vanhaelen, Quentin; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/ba30b908-e988-4768-8b64-03619d213219

Thesis Adenoviral Vector Mediated Transient Reprogramming of Cardiac Cells Towards Pluripotency

Kisby, Thomas · 2019 · University of Manchester · DOI

Full title: Adenoviral Vector Mediated Transient Reprogramming of Cardiac Cells Towards Pluripotency

Authors: Kisby, Thomas

Year: 2019

Venue: University of Manchester

DOI: https://research.manchester.ac.uk/en/studentTheses/7ea6eee7-cd07-4a40-9cc6-daeb1d1c6ec9

Thesis MicroRna-302 Switch to Identify and Eliminate Undifferentiated Human Pluripotent Stem Cells

Parr, Callum J.C.; Katayama, Shota; Miki, Kenji et al. · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: MicroRna-302 Switch to Identify and Eliminate Undifferentiated Human Pluripotent Stem Cells

Authors: Parr, Callum J.C.; Katayama, Shota; Miki, Kenji; Kuang, Yi; Yoshida, Yoshinori; Morizane, Asuka; Takahashi, Jun B.; Yamanaka, Shinya; Saito, Hirohide

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-91209

Thesis In Vitro Induction of Pluripotency from Equine Fibroblasts in 20% or 5% Oxygen

Castro, Raquel V. G. de [UNESP]; Pieri, Naira C. G.; Fantinato Neto, Paulo et al. · 2021 · Universidade Estadual Paulista (UNESP) · DOI

Full title: In Vitro Induction of Pluripotency from Equine Fibroblasts in 20% or 5% Oxygen

Authors: Castro, Raquel V. G. de [UNESP]; Pieri, Naira C. G.; Fantinato Neto, Paulo; Grizendi, Bianca M.; Doria, Renata G. S.; Meirelles, Flavio V.; Smith, Lawrence C.; Garcia, Joaquim M. [UNESP]; Bressan, Fabiana F.

Year: 2021

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1155/2020/8814989

Thesis 3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice

Guerrero, Ana; Innes, Andrew J; Roux, Pierre-François et al. · 2022 · Imperial College London · DOI

Full title: 3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice

Authors: Guerrero, Ana; Innes, Andrew J; Roux, Pierre-François; Buisman, Sonja C; Jung, Johannes; Ortet, Laura; Moiseeva, Victoria; Wagner, Verena; Robinson, Lucas; Ausema, Albertina; Potapova, Anna; Perdiguero, Eusebio; Weersing, Ellen; Aarts, Marieke; Martin, Nadine; Wuestefeld, Torsten; Muñoz-Cánoves, Pura; de Haan, Gerald; Bischof, Oliver; Gil, Jesús

Year: 2022

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/100501

Thesis Rejuvenation Modulation of Nucleus Pulposus Progenitor Cells Reverses Senescence-Associated Intervertebral Disc Degeneration

Zhao, Da‐wang; Zhang, Jing; Chen, Chen et al. · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Rejuvenation Modulation of Nucleus Pulposus Progenitor Cells Reverses Senescence-Associated Intervertebral Disc Degeneration

Authors: Zhao, Da‐wang; Zhang, Jing; Chen, Chen; Sun, Weiyi; Liu, Ying; Han, Maosen; Zhang, Yulin; Fu, Zhipeng; Shi, Chongdeng; Zhao, Xiaotian; Yang, Zhenmei; Tang, Chunwei; Zhao, Kun; Zhu, Bonnie Danqing; Zhang, Yuankai; Cheng, Lei; Jiang, Xinyi

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145177

Thesis Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing

Huerne, Katherine; Palmour, Nicole; Wu, Angela Ruohao et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing

Authors: Huerne, Katherine; Palmour, Nicole; Wu, Angela Ruohao; Beck, Stephan; Berner, Alison; Siebert, Reiner; Joly, Yann

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-117466

Thesis Spurious transcription may be a hallmark of aging

Isima, Nikita; Gil, Jesus · 2023 · Imperial College London · DOI

Full title: Spurious transcription may be a hallmark of aging

Authors: Isima, Nikita; Gil, Jesus

Year: 2023

Venue: Imperial College London

DOI: https://www.nature.com/articles/s43587-023-00398-x

Thesis CRISPR-knockout screen identifies Dmap1 as a regulator of chemically induced reprogramming and differentiation of cardiac progenitors

Yu, Jason SL; Palano, Giorgia; Lim, Cindy et al. · 2025 · Imperial College London · DOI

Full title: CRISPR-knockout screen identifies Dmap1 as a regulator of chemically induced reprogramming and differentiation of cardiac progenitors

Authors: Yu, Jason SL; Palano, Giorgia; Lim, Cindy; Moggio, Aldo; Drowley, Lauren; Plowright, Alleyn T; Bohlooly-Y, Mohammad; Rosen, Barry S; Hansson, Emil M; Wang, Qing-Dong; Yusa, Kosuke

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/121256

Thesis The E1a adenoviral gene upregulates the Yamanaka factors to induce partial cellular reprogramming

Mendoza, Gracia; González-Pastor, Rebeca; Sánchez, Juan Miguel et al. · 2023 · Imperial College London · DOI

Full title: The E1a adenoviral gene upregulates the Yamanaka factors to induce partial cellular reprogramming

Year: 2023

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/37174738

Thesis Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1

Martinez Corrales, Guillermo; Li, Mengjia; Svermova, Tatiana et al. · 2023 · Imperial College London · DOI

Full title: Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1

Authors: Martinez Corrales, Guillermo; Li, Mengjia; Svermova, Tatiana; Goncalves, Alex; Voicu, Diana; Dobson, Adam J; Southall, Tony D; Alic, Nazif

Year: 2023

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000916582800017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Identifying novel strategies to promote NK cell-mediated clearance of senescent cells

Reen, Virinder · 2025 · Imperial College London · DOI

Full title: Identifying novel strategies to promote NK cell-mediated clearance of senescent cells

Authors: Reen, Virinder

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/122955

Thesis Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells

Kues, Wilfried A.; Herrmann, Doris; Barg-Kues, Brigitte et al. · 2013 · University of Copenhagen · DOI

Full title: Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells

Authors: Kues, Wilfried A.; Herrmann, Doris; Barg-Kues, Brigitte; Haridoss, Srividiameena; Nowak-Imialek, Monika; Buchholz, Thomas; Streeck, Miriam; Grebe, Antonia; Grabundzija, Ivana; Merkert, Sylvia; Martin, Ulrich; Hall, Vanessa Jane; Rasmussen, Mikkel Aabech; Ivics, Zoltan; Hyttel, Poul; Niemann, Heiner

Year: 2013

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/c7898a62-bc27-4c60-84bd-75e0507fc813

Thesis Design and Production of mRNA-based Gene Vectors for Therapeutic Reprogramming of Cell Fate

Tolmachov, OE; Tolmachova, T · 2015 · Imperial College London · DOI

Full title: Design and Production of mRNA-based Gene Vectors for Therapeutic Reprogramming of Cell Fate

Authors: Tolmachov, OE; Tolmachova, T

Year: 2015

Venue: Imperial College London

DOI: http://www.researchgate.net/publication/274708170_Design_and_Production_of_mRNA-based_Gene_Vectors_for_Therapeutic_Reprogramming_of_Cell_Fate

Thesis Reversing DNA methylation by heterokaryon-mediated reprogramming

Piccolo, Francesco M. · 2014 · Imperial College London · DOI

Full title: Reversing DNA methylation by heterokaryon-mediated reprogramming

Authors: Piccolo, Francesco M.

Year: 2014

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/14505

Thesis A toolbox for the longitudinal assessment of healthspan in aging mice

Bellantuono, I; de Cabo, R; Ehninger, D et al. · 2024 · Imperial College London · DOI

Full title: A toolbox for the longitudinal assessment of healthspan in aging mice

Authors: Bellantuono, I; de Cabo, R; Ehninger, D; Di Germanio, C; Lawrie, A; Miller, J; Mitchell, SJ; Navas-Enamorado, I; Potter, PK; Tchkonia, T; Trejo, JL; Lamming, DW

Year: 2024

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000508183200005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Reprogramming of cell fate: epigenetic memory and the erasure of memories past.

Nashun, B; Hill, PW; Hajkova, P · 2015 · Imperial College London · DOI

Full title: Reprogramming of cell fate: epigenetic memory and the erasure of memories past.

Authors: Nashun, B; Hill, PW; Hajkova, P

Year: 2015

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/23210

Thesis Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

Voutila, J; Sætrom, P; Mintz, P et al. · 2016 · Imperial College London · DOI

Full title: Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

Authors: Voutila, J; Sætrom, P; Mintz, P; Sun, G; Alluin, J; Rossi, J; Habib, N; Kasahara, N

Year: 2016

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/38656

Thesis Identification of genes involved in reprogramming-induced senescence

Beolchi, Patrizia · 2017 · Imperial College London · DOI

Full title: Identification of genes involved in reprogramming-induced senescence

Authors: Beolchi, Patrizia

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/44980

Thesis Ageing: out with the old

Gil, J; Withers, DJ · 2016 · Imperial College London · DOI

Full title: Ageing: out with the old

Authors: Gil, J; Withers, DJ

Year: 2016

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/34126

Thesis Epigenetic reprogramming and DNA demethylation

Bagci, Hakan · 2017 · Imperial College London · DOI

Full title: Epigenetic reprogramming and DNA demethylation

Authors: Bagci, Hakan

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/45352

Thesis Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease

Cantone, I; Fisher, AG · 2017 · Imperial College London · DOI

Full title: Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease

Authors: Cantone, I; Fisher, AG

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/43703

Thesis Senescence and aging – causes, consequences, and therapeutic avenues

McHugh, D; Gil, J · 2017 · Imperial College London · DOI

Full title: Senescence and aging – causes, consequences, and therapeutic avenues

Authors: McHugh, D; Gil, J

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/52021

Thesis Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

Fisher, AG · 2016 · Imperial College London · DOI

Full title: Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

Authors: Fisher, AG

Year: 2016

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/39065

Thesis Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation

Cantone, I; Dharmalingam, G; Chan, YW et al. · 2017 · Imperial College London · DOI

Full title: Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation

Authors: Cantone, I; Dharmalingam, G; Chan, YW; Kohler, AC; Lenhard, B; Merkenschlager, M; Fisher, AG

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/43971

Thesis Coupling shRNA screens with single-cell RNA-Seq identifies a dual role for mTOR in reprogramming-induced senescence

Aarts, M; Georgilis, A; Beniazza, M et al. · 2017 · Imperial College London · DOI

Full title: Coupling shRNA screens with single-cell RNA-Seq identifies a dual role for mTOR in reprogramming-induced senescence

Authors: Aarts, M; Georgilis, A; Beniazza, M; Beolchi, P; Banito, A; Carroll, T; Kulisic, M; Kaemena, DF; Dharmalingam, G; Martin, N; Reik, W; Zuber, J; Kaji, K; Chandra, T; Gil, J

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/52022

Thesis Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease

Birch, Jodie; Barnes, Peter J; Passos, Joao F · 2017 · Imperial College London · DOI

Full title: Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease

Authors: Birch, Jodie; Barnes, Peter J; Passos, Joao F

Year: 2017

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/28987319

Thesis Senescence impairs successful reprogramming to pluripotent stem cells

Banito, Ana Cristina Tome Moita; Banito, Ana Cristina Tome Moita · 2011 · Imperial College London · DOI

Full title: Senescence impairs successful reprogramming to pluripotent stem cells

Authors: Banito, Ana Cristina Tome Moita; Banito, Ana Cristina Tome Moita

Year: 2011

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/6875

Thesis Cell type of origin dictates the route to pluripotency

Nefzger, Christian M; Rossello, Fernando J; Chen, Joseph et al. · 2018 · Imperial College London · DOI

Full title: Cell type of origin dictates the route to pluripotency

Authors: Nefzger, Christian M; Rossello, Fernando J; Chen, Joseph; Liu, Xiaodong; Knaupp, Anja S; Firas, Jaber; Paynter, Jacob M; Pflueger, Jahnvi; Buckberry, Sam; Lim, Sue Mei; Williams, Brenda; Alaei, Sara; Faye-Chauhan, Keshav; Petretto, Enrico; Nilsson, Susan K; Lister, Ryan; Ramialison, Mirana; Powell, David R; Rackham, Owen JL; Polo, Jose M

Year: 2018

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000417146000002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis A unique gene regulatory network resets the human germline epigenome for development

Tang, Walfred WC; Dietmann, Sabine; Irie, Naoko et al. · 2018 · Imperial College London · DOI

Full title: A unique gene regulatory network resets the human germline epigenome for development

Authors: Tang, Walfred WC; Dietmann, Sabine; Irie, Naoko; Leitch, Harry G; Floros, Vasileios I; Bradshaw, Charles R; Hackett, Jamie A; Chinnery, Patrick F; Surani, M Azim

Year: 2018

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000355935000022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Veterinary applications of induced pluripotent stem cells: Regenerative medicine and models for disease?

Cebrian-Serrano, A.; Stout, T.A.E.; Dinnyes, A. · 2013 · Utrecht University · DOI

Full title: Veterinary applications of induced pluripotent stem cells: Regenerative medicine and models for disease?

Authors: Cebrian-Serrano, A.; Stout, T.A.E.; Dinnyes, A.

Year: 2013

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/291255

Thesis Is aging a barrier to reprogramming? Lessons from induced pluripotent stem cells.

Phanthong, P.; Raveh-Amit, H.; Li, T. et al. · 2013 · Utrecht University · DOI

Full title: Is aging a barrier to reprogramming? Lessons from induced pluripotent stem cells.

Authors: Phanthong, P.; Raveh-Amit, H.; Li, T.; Kitiyanant, Y.; Dinnyes, A.J.

Year: 2013

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/291271

Thesis Genome-wide characterization of the routes to pluripotency

Hussein, Samer M I; Puri, Mira C; Tonge, Peter D et al. · 2014 · Utrecht University · DOI

Full title: Genome-wide characterization of the routes to pluripotency

Authors: Hussein, Samer M I; Puri, Mira C; Tonge, Peter D; Benevento, Marco; Corso, Andrew J; Clancy, Jennifer L; Mosbergen, Rowland; Li, Mira; Lee, Dong-Sung; Cloonan, Nicole; Wood, David L A; Munoz, Javier; Middleton, Robert; Korn, Othmar; Patel, Hardip R; White, Carl A; Shin, Jong-Yeon; Gauthier, Maely E; Lê Cao, Kim-Anh; Kim, Jong-Il; Mar, Jessica C; Shakiba, Nika; Ritchie, William; Rasko, John E J; Grimmond, Sean M; Zandstra, Peter W; Wells, Christine A; Preiss, Thomas; Seo, Jeong-Sun; Heck, Albert J R; Rogers, Ian M; Nagy, Andras

Year: 2014

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/304103

Thesis Defined three-dimensional microenvironments boost induction of pluripotency

Caiazzo, Massimiliano; Okawa, Yuya; Ranga, Adrian et al. · 2016 · Utrecht University · DOI

Full title: Defined three-dimensional microenvironments boost induction of pluripotency

Authors: Caiazzo, Massimiliano; Okawa, Yuya; Ranga, Adrian; Piersigilli, Alessandra; Tabata, Yoji; Lutolf, Matthias P

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/346253

Thesis Investigating reprogramming factors and neural conditions to convert human dental pulp stem cells into neural stem cells

Gancheva, Maria Roumenova · 2020 · University of Adelaide · DOI

Full title: Investigating reprogramming factors and neural conditions to convert human dental pulp stem cells into neural stem cells

Authors: Gancheva, Maria Roumenova

Year: 2020

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/132887

Thesis Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury

Shakked, Avraham; Petrover, Zachary; Aharonov, Alla et al. · 2023 · Utrecht University · DOI

Full title: Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury

Authors: Shakked, Avraham; Petrover, Zachary; Aharonov, Alla; Ghiringhelli, Matteo; Umansky, Kfir Baruch; Kain, David; Elkahal, Jacob; Divinsky, Yalin; Nguyen, Phong Dang; Miyara, Shoval; Friedlander, Gilgi; Savidor, Alon; Zhang, Lingling; Perez, Dahlia E.; Sarig, Rachel; Lendengolts, Daria; Bueno-Levy, Hanna; Kastan, Nathaniel; Levin, Yishai; Bakkers, Jeroen; Gepstein, Lior; Tzahor, Eldad

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451300

Thesis YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo

Monroe, Tanner O.; Hill, Matthew C.; Morikawa, Yuka et al. · 2019 · Utrecht University · DOI

Full title: YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo

Authors: Monroe, Tanner O.; Hill, Matthew C.; Morikawa, Yuka; Leach, John P.; Heallen, Todd; Cao, Shuyi; Krijger, Peter H.L.; de Laat, Wouter; Wehrens, Xander H.T.; Rodney, George G.; Martin, James F.

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439385

Thesis Engineering cell fate: Applying synthetic biology to cellular reprogramming

Wang, Nathan B; Beitz, Adam M; Galloway, Katie · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Engineering cell fate: Applying synthetic biology to cellular reprogramming

Authors: Wang, Nathan B; Beitz, Adam M; Galloway, Katie

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133290

Thesis Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins

Angel, Matthew; Yanik, Mehmet Fatih · 2010 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins

Authors: Angel, Matthew; Yanik, Mehmet Fatih

Year: 2010

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/60359

Thesis Small molecules enable highly efficient neuronal conversion of human fibroblasts

Ladewig, Julia; Mertens, Jerome; Kesavan, Jaideep et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Small molecules enable highly efficient neuronal conversion of human fibroblasts

Authors: Ladewig, Julia; Mertens, Jerome; Kesavan, Jaideep; Doerr, Jonas; Poppe, Daniel; Glaue, Finnja; Herms, Stefan; Wernet, Peter; Kögler, Gesine; Müller, Franz-Josef; Koch, Philipp; Brüstle, Oliver

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/138681

Thesis Epigenome Editing for Reprogramming Neuronal Cell Fate Specification

Black, Joshua Benjamin · 2020 · Duke University · DOI

Full title: Epigenome Editing for Reprogramming Neuronal Cell Fate Specification

Authors: Black, Joshua Benjamin

Year: 2020

Venue: Duke University

DOI: https://hdl.handle.net/10161/19830

Thesis Methods for Comparative Analysis of Chromatin Accessibility and Gene Expression, With Applications to Cellular Reprogramming

Manandhar, Dinesh · 2018 · Duke University · DOI

Full title: Methods for Comparative Analysis of Chromatin Accessibility and Gene Expression, With Applications to Cellular Reprogramming

Authors: Manandhar, Dinesh

Year: 2018

Venue: Duke University

DOI: https://hdl.handle.net/10161/16843

Thesis A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors

Riva, C; Hajduskova, M; Gally, C et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors

Authors: Riva, C; Hajduskova, M; Gally, C; Suman, SK; Ahier, A; Jarriault, S

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/56723

Thesis Impact papers on aging in 2009

Blagosklonny, M. V.; Campisi, J.; Sinclair, D. A. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Impact papers on aging in 2009

Authors: Blagosklonny, M. V.; Campisi, J.; Sinclair, D. A.; Bartke, A.; Blasco, M. A.; Bonner, W. M.; Bohr, V. A.; Brosh, R. M.; Brunet, A.; Depinho, R. A.; Donehower, L. A.; Finch, C. E.; Finkel, T.; Gorospe, M.; Gudkov, A. V.; Hall, M. N.; Hekimi, S.; Helfand, S. L.; Karlseder, J.; Kenyon, C.; Kroemer, G.; Longo, V.; Nussenzweig, A.; Osiewacz, H. D.; Peeper, D. S.; Rando, T. A.; Rudolph, K. L.; Sassone-Corsi, P.; Serrano, M.; Sharpless, N. E.; Skulachev, V. P.; Tilly, J. L.; Tower, J.; Verdin, E.; Vijg, J.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/79765

Thesis Smad2/3 potentiate cell identity conversions with master transcription factors

Ruetz, Tyson Joel · 2017 · The University of Edinburgh · DOI

Full title: Smad2/3 potentiate cell identity conversions with master transcription factors

Authors: Ruetz, Tyson Joel

Year: 2017

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/21703

Thesis Identifying novel regulators of reprogramming using RNA interference

Brightwell, Sara · 2016 · The University of Edinburgh · DOI

Full title: Identifying novel regulators of reprogramming using RNA interference

Authors: Brightwell, Sara

Year: 2016

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/16156

Thesis Reprogramming peripheral blood mononuclear cells using an efficient feeder-free, non-integration method to generate iPS cells and the effect of immunophenotype and epigenetic state on HSPC fate

Liu, Jing · 2015 · The University of Edinburgh · DOI

Full title: Reprogramming peripheral blood mononuclear cells using an efficient feeder-free, non-integration method to generate iPS cells and the effect of immunophenotype and epigenetic state on HSPC fate

Authors: Liu, Jing

Year: 2015

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/10031

Thesis Synthetic Biology-Based Approaches to Enhance Transgene Attributes

Chakraborty, Syandan · 2014 · Duke University · DOI

Full title: Synthetic Biology-Based Approaches to Enhance Transgene Attributes

Authors: Chakraborty, Syandan

Year: 2014

Venue: Duke University

DOI: https://hdl.handle.net/10161/9079

Thesis Characterising the in vitro conversion of mouse fibroblasts into induced neurons using a CRISPR/Cas9 knock-out screen

Carbone, Benedetta · 2020 · The University of Edinburgh · DOI

Full title: Characterising the in vitro conversion of mouse fibroblasts into induced neurons using a CRISPR/Cas9 knock-out screen

Authors: Carbone, Benedetta

Year: 2020

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/36981

Thesis Immortalisation of primary cell lines as tools for investigation into feline diseases

Adamson, Louise · 2024 · The University of Edinburgh · DOI

Full title: Immortalisation of primary cell lines as tools for investigation into feline diseases

Authors: Adamson, Louise

Year: 2024

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/42310

Thesis Novel cell surface markers identify routes to iPS cells

O'Malley, James · 2014 · The University of Edinburgh · DOI

Full title: Novel cell surface markers identify routes to iPS cells

Authors: O'Malley, James

Year: 2014

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/8883

Thesis Understanding the heterogeneity of senescence and ageing at the single-cell level

Rattanavirotkul, Nattaphong · 2020 · The University of Edinburgh · DOI

Full title: Understanding the heterogeneity of senescence and ageing at the single-cell level

Authors: Rattanavirotkul, Nattaphong

Year: 2020

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/36718

Thesis Transcriptional and Epigenetic Dynamics Underlying Direct Cardiac Reprogramming

Stone, Nicole · 2017 · University of California, San Francisco (UCSF) · DOI

Full title: Transcriptional and Epigenetic Dynamics Underlying Direct Cardiac Reprogramming

Authors: Stone, Nicole

Year: 2017

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/2ht942dr

Thesis Epigenetic age prediction and rejuvenation

Simpson, Daniel J. · 2022 · The University of Edinburgh · DOI

Full title: Epigenetic age prediction and rejuvenation

Authors: Simpson, Daniel J.

Year: 2022

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/38463

Thesis Characterization of YY1, RUNX1, NFIB, and PPARG: A Study in Aged Human Induced Neurons

Vajaphattana, Yatavee · 2023 · University of California, San Diego (UCSD) · DOI

Full title: Characterization of YY1, RUNX1, NFIB, and PPARG: A Study in Aged Human Induced Neurons

Authors: Vajaphattana, Yatavee

Year: 2023

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/62n1t500

Thesis Discovery of a Cellular Mechanism Regulating Transcriptional Noise

Desai, Ravi · 2020 · University of California, San Francisco (UCSF) · DOI

Full title: Discovery of a Cellular Mechanism Regulating Transcriptional Noise

Authors: Desai, Ravi

Year: 2020

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/7gt3r1vn

Thesis Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2

Pereira, Carlos F; Terranova, Remi; Ryan, Natalie K et al. · 2019 · Imperial College London · DOI

Full title: Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2

Authors: Pereira, Carlos F; Terranova, Remi; Ryan, Natalie K; Santos, Joana; Morris, Kelly J; Cui, Wei; Merkenschlager, Matthias; Fisher, Amanda G

Year: 2019

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000260411200024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Mammalian models of extended healthy lifespan

Selman, Colin; Withers, Dominic J · 2020 · Imperial College London · DOI

Full title: Mammalian models of extended healthy lifespan

Authors: Selman, Colin; Withers, Dominic J

Year: 2020

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000284718700015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2021 · Imperial College London · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Soren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin Y; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G; Georgievskaya, Anastasia; Gladyshev, Vadim N; Glass, David J; Gorbunova, Vera; de Grey, Aubrey; He, Wei-Wu; Hoeijmakers, Jan; Hoffmann, Eva; Horvath, Steve; Houtkooper, Riekelt H; Jensen, Majken K; Jensen, Martin Borch; Kane, Alice; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian; Karsenty, Gerard; Lamming, Dudley W; Lee, Kai-Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura; Osborne, Brenna; Pak, Heidi H; Parkhitko, Andrey; Raimundo, Nuno; Rando, Thomas A; Rasmussen, Lene Juel; Reis, Carolina; Riedel, Christian G; Franco-Romero, Anais; Schumacher, Bjoern; Sinclair, David A; Suh, Yousin; Taub, Pam R; Toiber, Debra; Treebak, Jonas T; Valenzano, Dario Riccardo; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000605608700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor

Tawechaipaisankul, Anukul; Jin, Jun-Xue; Lee, Sanghoon et al. · 2023 · Seoul National University · DOI

Full title: Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor

Authors: Tawechaipaisankul, Anukul; Jin, Jun-Xue; Lee, Sanghoon; Kim, Geon A; Suh, Yoon Ho; Ahn, Min Seok; Park, Se Jun; Lee, Byeong You; Lee, Byeong Chun

Year: 2023

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/191024

Thesis To help aging populations, classify organismal senescence

Calimport, Stuart RG; Bentley, Barry L; Stewart, Claire E et al. · 2019 · Imperial College London · DOI

Full title: To help aging populations, classify organismal senescence

Authors: Calimport, Stuart RG; Bentley, Barry L; Stewart, Claire E; Pawelec, Graham; Scuteri, Angelo; Vinciguerra, Manlio; Slack, Cathy; Chen, Danica; Harries, Lorna W; Marchant, Gary; Fleming, G Alexander; Conboy, Michael; Antebi, Adam; Small, Gary W; Gil, Jesus; Lakatta, Edward G; Richardson, Arlan; Rosen, Clifford; Nikolich, Karoly; Wyss-Coray, Tony; Steinman, Lawrence; Montine, Thomas; de Magalhães, João Pedro; Campisi, Judith; Church, George

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/74552

Thesis Reconstitution of the oocyte transcriptional network with transcription factors

Hamazaki, Nobuhiko; Kyogoku, Hirohisa; Araki, Hiromitsu et al. · 2021 · Imperial College London · DOI

Full title: Reconstitution of the oocyte transcriptional network with transcription factors

Authors: Hamazaki, Nobuhiko; Kyogoku, Hirohisa; Araki, Hiromitsu; Miura, Fumihito; Horikawa, Chisako; Hamada, Norio; Shimamoto, So; Hikabe, Orie; Nakashima, Kinichi; Kitajima, Tomoya S; Ito, Takashi; Leitch, Harry G; Hayashi, Katsuhiko

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000599487900003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Using ontologies to study cell transitions

Fuellen, Georg; Jansen, Ludger; Leser, Ulf et al. · 2023 · Seoul National University · DOI

Full title: Using ontologies to study cell transitions

Authors: Fuellen, Georg; Jansen, Ludger; Leser, Ulf; Kurtz, Andreas

Year: 2023

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/192315

Thesis Enhancement of epigenetic reprogramming status of porcine cloned embryos with zebularine, a DNA methyltransferase inhibitor

Taweechaipaisankul, Anukul; Kim, Geon A.; Jin, Jun-Xue et al. · 2023 · Seoul National University · DOI

Full title: Enhancement of epigenetic reprogramming status of porcine cloned embryos with zebularine, a DNA methyltransferase inhibitor

Authors: Taweechaipaisankul, Anukul; Kim, Geon A.; Jin, Jun-Xue; Lee, Sanghoon; Qasim, Muhammad; Kim, Eui Hyun; Lee, Byeong Chun

Year: 2023

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/197986

Thesis The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

Patrick, Ralph; Naval-Sanchez, Marina; Deshpande, Nikita et al. · 2024 · UNSW Sydney · DOI

Full title: The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

Authors: Patrick, Ralph; Naval-Sanchez, Marina; Deshpande, Nikita; Huang, Yifei; Zhang, Jingyu; Chen, Xiaoli; Yang, Ying; Tiwari, Kanupriya; Esmaeili, Mohammadhossein; Tran, Minh ; https://orcid.org/0000-0003-1088-0243; Mohamed, Amin R; Wang, Binxu; Xia, Di; Ma, Jun; Bayliss, Jacqueline; Wong, Kahlia; Hun, Michael L; Sun, Xuan; Cao, Benjamin; Cottle, Denny L; Catterall, Tara; Barzilai-Tutsch, Hila; Troskie, Robin-Lee; Chen, Zhian; Wise, Andrea F; Saini, Sheetal; Soe, Ye Mon; Kumari, Snehlata; Sweet, Matthew J; Thomas, Helen E; Smyth, Ian M; Fletcher, Anne L; Knoblich, Konstantin; Watt, Matthew J; Alhomrani, Majid; Alsanie, Walaa; Quinn, Kylie M; Merson, Tobias D; Chidgey, Ann P; Ricardo, Sharon D; Yu, Di; Jardé, Thierry; Cheetham, Seth W; Marcelle, Christophe; Nilsson, Susan K; Nguyen, Quan; White, Melanie D; Nefzger, Christian M

Year: 2024

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/102642

Thesis Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.

Baumgart, Mario; Priebe, Steffen; Groth, Marco et al. · 2016 · University of Cambridge · DOI

Full title: Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.

Authors: Baumgart, Mario; Priebe, Steffen; Groth, Marco; Hartmann, Nils; Menzel, Uwe; Pandolfini, Luca; Koch, Philipp; Felder, Marius; Ristow, Michael; Englert, Christoph; Guthke, Reinhard; Platzer, Matthias; Cellerino, Alessandro

Year: 2016

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/254080

Thesis MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.

Eckersley-Maslin, Mélanie A; Svensson, Valentine; Krueger, Christel et al. · 2019 · University of Cambridge · DOI

Full title: MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.

Authors: Eckersley-Maslin, Mélanie A; Svensson, Valentine; Krueger, Christel; Stubbs, Thomas M; Giehr, Pascal; Krueger, Felix; Miragaia, Ricardo J; Kyriakopoulos, Charalampos; Berrens, Rebecca V; Milagre, Inês; Walter, Jörn; Teichmann, Sarah A; Reik, Wolf

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/292873

Thesis Cell reprogramming shapes the mitochondrial DNA landscape.

Wei, Wei; Gaffney, Daniel J; Chinnery, Patrick F · 2021 · University of Cambridge · DOI

Full title: Cell reprogramming shapes the mitochondrial DNA landscape.

Authors: Wei, Wei; Gaffney, Daniel J; Chinnery, Patrick F

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/328995

Thesis Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency.

Bredenkamp, Nicholas; Yang, Jian; Clarke, James et al. · 2019 · University of Cambridge · DOI

Full title: Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency.

Authors: Bredenkamp, Nicholas; Yang, Jian; Clarke, James; Stirparo, Giuliano Giuseppe; von Meyenn, Ferdinand; Dietmann, Sabine; Baker, Duncan; Drummond, Rosalind; Ren, Yongming; Li, Dongwei; Wu, Chuman; Rostovskaya, Maria; Eminli-Meissner, Sarah; Smith, Austin; Guo, Ge

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/297875

Thesis Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Gill, Diljeet; Parry, Aled; Santos, Fátima et al. · 2022 · University of Cambridge · DOI

Full title: Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Authors: Gill, Diljeet; Parry, Aled; Santos, Fátima; Okkenhaug, Hanneke; Todd, Christopher D; Hernando-Herraez, Irene; Stubbs, Thomas M; Milagre, Inês; Reik, Wolf

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/336357

Thesis Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle et al. · 2022 · University of Cambridge · DOI

Full title: Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Authors: Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle; Stoker, Tom; Barker, Roger A; Rylander Ottosson, Daniella

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/333320

Thesis Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan

Baumgart, Mario; Priebe, Steffen; Groth, Marco et al. · 2016 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan

Year: 2016

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/114035

Thesis Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Wen, Ming-Hsuan; Barbosa Triana, Hector; Butler, Richard et al. · 2024 · University of Cambridge · DOI

Full title: Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Authors: Wen, Ming-Hsuan; Barbosa Triana, Hector; Butler, Richard; Hu, Hsiang-Wei; Dai, Yang-Hong; Lawrence, Nicola; Hong, Jun-Jie; Garrett, Nigel; Jones-Green, Rue; Rawlins, Emma L; Dong, Ziqi; Koziol, Magdalena J; Gurdon, JB

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/366158

Thesis Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins

Angel, Matthew; Yanik, Mehmet F. · 2010 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins

Authors: Angel, Matthew; Yanik, Mehmet F.

Year: 2010

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/107587

Thesis Reprogramming Roadblocks Are System Dependent

Chantzoura, Eleni; Skylaki, Stavroula; Menéndez, Sergio et al. · 2015 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Reprogramming Roadblocks Are System Dependent

Authors: Chantzoura, Eleni; Skylaki, Stavroula; Menéndez, Sergio; Kim, Shin-Il; Johnsson, Anna; Linnarsson, Sten; Woltjen, Knut; Chambers, Ian; Kaji, Keisuke

Year: 2015

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/112055

Thesis Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

Liu, Lin L.; Brumbaugh, Justin; Bar-Nur, Ori et al. · 2016 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

Authors: Liu, Lin L.; Brumbaugh, Justin; Bar-Nur, Ori; id_orcid0000-0002-6466-3124; Smith, Zachary; Stadtfeld, Matthias; Meissner, Alexander; Hochedlinger, Konrad; Michor, Franziska

Year: 2016

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/314650

Thesis Changing cells: An analysis of the concept of plasticity in the context of cellular differentiation

Kraft, Alison; Rubin, Beatrix P. · 2016 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Changing cells: An analysis of the concept of plasticity in the context of cellular differentiation

Authors: Kraft, Alison; Rubin, Beatrix P.

Year: 2016

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/126615

Thesis Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

Bar-Nur, Ori; id_orcid0000-0002-6466-3124; Gerli, Mattia F. M. et al. · 2018 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

Authors: Bar-Nur, Ori; id_orcid0000-0002-6466-3124; Gerli, Mattia F. M.; Di Stefano, Bruno; Almada, Albert E.; Galvin, Amy; Coffey, Amy; Huebner, Aaron J.; Feige, Peter; Verheul, Cassandra; Cheung, Priscilla; Payzin-Dogru, Duygu; Paisant, Sylvain; Anselmo, Anthony; Sadreyev, Ruslan I.; Ott, Harald C.; Tajbakhsh, Shahragim; Rudnicki, Michael A.; Wagers, Amy J.; Hochedlinger, Konrad

Year: 2018

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/267661

Thesis Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control

Cavinato, Maria; Madreiter-Sokolowski, Corina T.; Büttner, Sabrina et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control

Authors: Cavinato, Maria; Madreiter-Sokolowski, Corina T.; Büttner, Sabrina; Schosserer, Markus; Zwerschke, Werner; Wedel, Sophia; Grillari, Johannes; Graier, Wolfgang F.; Jansen-Dürr, Pidder

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/458310

Thesis OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates

Kagawa, Harunobu; Shimamoto, Ren; Kim, Shin-Il et al. · 2019 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates

Authors: Kagawa, Harunobu; Shimamoto, Ren; Kim, Shin-Il; Oceguera-Yanez, Fabian; Yamamoto, Takuya; Schroeder, Timm; Woltjen, Knut

Year: 2019

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/324081

Thesis Analysis of transcriptional modules during human fibroblast ageing

Lee, Yaelim; Shivashankar, G.V. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Analysis of transcriptional modules during human fibroblast ageing

Authors: Lee, Yaelim; Shivashankar, G.V.

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/451366

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Søren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin; id_orcid0000-0003-1166-4171; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David J.; Gorbunova, Vera A.; de Grey, Aubrey; He, Weiwu; Hoeijmakers, Jan H.; Hoffmann, Eva R.; Horvath, Steve M.; Houtkooper, Riekelt H.; Jensen, Majken K.; Jensen, Martin B.; Kane, Alice E.; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian K.; Karsenty, Gerard; Lamming, Dudley W.; Lee, Kai Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura J.; Osborne, Brenna; Pak, Heidi H.; Parkhitko, Andrey A.; Raimundo, Nuno; Rando, Thomas A.; Juel Rasmussen, Lene; Reis, Carolina; Riedel, Christian G.; Franco-Romero, Anais; Schumacher, Björn; Sinclair, David A.; Suh, Yousin; Taub, Pam R.; Toiber, Debra; Treebak, Jonas T.; Valenzano, Dario R.; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/466960

Thesis Fibroblast rejuvenation by mechanical reprogramming and redifferentiation

Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Fibroblast rejuvenation by mechanical reprogramming and redifferentiation

Authors: Roy, Bibhas; Yuan, Luezhen; Lee, Yaelim; Bharti, Aradhana; Mitra, Aninda; Shivashankar, G.V.

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/415875

Thesis Human iPSCs and Genome Editing Technologies for Precision Cardiovascular Tissue Engineering

Gähwiler, Eric K.N.; Motta, Sarah E.; Martin, Marcy et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Human iPSCs and Genome Editing Technologies for Precision Cardiovascular Tissue Engineering

Authors: Gähwiler, Eric K.N.; Motta, Sarah E.; Martin, Marcy; Nugraha, Bramasta; Hoerstrup, Simon P.; Emmert, Maximilian Y.

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/495620

Thesis Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture

Daniel, Michael G.; Sachs, David; Bernitz, Jeffrey M. et al. · 2019 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture

Authors: Daniel, Michael G.; Sachs, David; Bernitz, Jeffrey M.; Fstkchyan, Yesai; Rapp, Katrina; Satija, Namita; Law, Kenneth; Patel, Foram; Gomes, Andreia M.; Kim, Huen-Suk; Pereira, Carlos-Filipe; Chen, Benjamin; Lemischka, Ihor R.; Moore, Kateri A.

Year: 2019

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/372263

Thesis Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

Qabrati, Xhem; Kim, Inseon; Ghosh, Adhideb et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

Authors: Qabrati, Xhem; Kim, Inseon; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Bundschuh, Nicola; Noé, Falko; Palmer, Andrew S.; Bar-Nur, Ori; id_orcid0000-0002-5160-4571

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/626174

Thesis Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells

Kim, Inseon; Ghosh, Adhideb; id_orcid0000-0002-5160-4571 et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells

Authors: Kim, Inseon; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Bundschuh, Nicola; Hinte, Laura; Petrosyan, Eduard; von Meyenn, Ferdinand; id_orcid0000-0002-5160-4571; Bar-Nur, Ori; id_orcid0000-0002-5160-4571

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/542515

Thesis Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells

Yagi, Masaki; Ji, Fei; Charlton, Jocelyn et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells

Authors: Yagi, Masaki; Ji, Fei; Charlton, Jocelyn; Cristea, Simona; Messemer, Kathleen; Horwitz, Naftali; Di Stefano, Bruno; Tsopoulidis, Nikolaos; Hoetker, Michael S.; Huebner, Aaron J.; Bar-Nur, Ori; id_orcid0000-0002-6466-3124; Almada, Albert E.; Yamamoto, Masakazu; Patelunas, Anthony; Goldhamer, David J.; Wagers, Amy J.; Michor, Franziska; Meissner, Alexander; Sadreyev, Ruslan I.; Hochedlinger, Konrad

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/505029

Thesis Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle

Blocquiaux, Sara; Ramaekers, Monique; Van Thienen, Ruud et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle

Authors: Blocquiaux, Sara; Ramaekers, Monique; Van Thienen, Ruud; Nielens, Henri; Delecluse, Christophe; De Bock, Katrien; id_orcid0000-0001-8232-4663; Thomis, Martine

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/531544

Thesis Ingestion of single guide RNAs induces gene overexpression and extends lifespan in Caenorhabditis elegans via CRISPR activation

Fischer, Fabian; Benner, Christoph; Goyala, Anita et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Ingestion of single guide RNAs induces gene overexpression and extends lifespan in Caenorhabditis elegans via CRISPR activation

Authors: Fischer, Fabian; Benner, Christoph; Goyala, Anita; Grigolon, Giovanna; Vitiello, Davide; Wu, Jia Yee; Zarse, Kim; Ewald, Collin; id_orcid0000-0003-1166-4171; Ristow, Michael; id_orcid0000-0003-1166-4171

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/555534

Thesis Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Bachamanda Somesh, Dipthi; Klose, Kristin; Maring, Janita A. et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Authors: Bachamanda Somesh, Dipthi; Klose, Kristin; Maring, Janita A.; Kunkel, Désirée; Jürchott, Karsten; Protze, Stephanie I.; Klein, Oliver; Nebrich, Grit; Becker, Matthias; Krüger, Ulrike; Nazari-Shafti, Timo Z.; Falk, Volkmar; Kurtz, Andreas; Gossen, Manfred; Stamm, Christof

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/638618

Thesis BRCA1 and 53BP1 Mediate Reprogramming Through DNA Repair Pathway Choice

Georgieva, Daniela Chavdarova · 2019 · Columbia University · DOI

Full title: BRCA1 and 53BP1 Mediate Reprogramming Through DNA Repair Pathway Choice

Authors: Georgieva, Daniela Chavdarova

Year: 2019

Venue: Columbia University

DOI: https://doi.org/10.7916/d8-8hx3-4x61

Thesis Systems Biology Approaches to The Study of Neurological Disorders and Somatic Cell Reprogramming

Shin, William Kihoon · 2016 · Columbia University · DOI

Full title: Systems Biology Approaches to The Study of Neurological Disorders and Somatic Cell Reprogramming

Authors: Shin, William Kihoon

Year: 2016

Venue: Columbia University

DOI: https://doi.org/10.7916/D8CR5TV2

Thesis IDENTIFICATION OF EPIGENETIC INHIBITORS OF PHYSIOLOGICAL CELLULAR PLASTICITY AS NOVEL TUMOR SUPPRESSOR

XIERAILI, AOBULI · 2019 · Università degli Studi di Milano (AIR) · DOI

Full title: IDENTIFICATION OF EPIGENETIC INHIBITORS OF PHYSIOLOGICAL CELLULAR PLASTICITY AS NOVEL TUMOR SUPPRESSOR

Authors: XIERAILI, AOBULI

Year: 2019

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/609578

Thesis Manipulating Somatic Cells to Remove Barriers in Induced Pluripotent Stem Cell Reprogramming

Chung, Julia · 2013 · Harvard University - DASH · DOI

Full title: Manipulating Somatic Cells to Remove Barriers in Induced Pluripotent Stem Cell Reprogramming

Authors: Chung, Julia

Year: 2013

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:10772

Thesis Defining markers and mechanisms of human somatic cell reprogramming

Ratanasirintrawoot, Sutheera · 2014 · Harvard University - DASH · DOI

Full title: Defining markers and mechanisms of human somatic cell reprogramming

Authors: Ratanasirintrawoot, Sutheera

Year: 2014

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:11236

Thesis Reversal of Aging via in Vivo Epigenetic Reprogramming

Lu, Yuancheng · 2020 · Harvard University - DASH · DOI

Full title: Reversal of Aging via in Vivo Epigenetic Reprogramming

Authors: Lu, Yuancheng

Year: 2020

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365788

Thesis Bioinformatic and molecular study of the regulation of SIRT3 expression

Satterstrom, F. Kyle Kyle · 2015 · Harvard University - DASH · DOI

Full title: Bioinformatic and molecular study of the regulation of SIRT3 expression

Authors: Satterstrom, F. Kyle Kyle

Year: 2015

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226041

Thesis Deprogramming senescence by genomic stabilizing molecules in vivo

Yasom, Sakawdaurn · 2021 · Chulalongkorn University · DOI

Full title: Deprogramming senescence by genomic stabilizing molecules in vivo

Authors: Yasom, Sakawdaurn

Year: 2021

Venue: Chulalongkorn University

DOI: https://digital.car.chula.ac.th/chulaetd/4563

Thesis Exploring the Plasticity of Cellular Fate Using Defined-Factor Reprogramming

Son, Yesde · 2012 · Harvard University - DASH · DOI

Full title: Exploring the Plasticity of Cellular Fate Using Defined-Factor Reprogramming

Authors: Son, Yesde

Year: 2012

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:10309

Thesis Engineering whole-body gene therapies for aging

Florea, Michael · 2023 · Harvard University - DASH · DOI

Full title: Engineering whole-body gene therapies for aging

Authors: Florea, Michael

Year: 2023

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375576

Thesis The effects of recombinant Oct4 and Sox2 proteins on pluripotent genes expression in mouse somatic cells

Suphankong, Sirilada · 2009 · Chulalongkorn University · DOI

Full title: The effects of recombinant Oct4 and Sox2 proteins on pluripotent genes expression in mouse somatic cells

Authors: Suphankong, Sirilada

Year: 2009

Venue: Chulalongkorn University

DOI: https://digital.car.chula.ac.th/chulaetd/44487

Thesis Emerging strategies for biological age reversal

Zhang, Bohan · 2022 · Harvard University - DASH · DOI

Full title: Emerging strategies for biological age reversal

Authors: Zhang, Bohan

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372072

Thesis A central role for TFIID in the pluripotent transcription circuitry

Pijnappel, W.W.M.; Esch, D.; Baltissen, M.P.A. et al. · 2013 · Utrecht University · DOI

Full title: A central role for TFIID in the pluripotent transcription circuitry

Authors: Pijnappel, W.W.M.; Esch, D.; Baltissen, M.P.A.; Wu, G.; Mischerikow, N.; Bergsma, A.; van der Wal, E.; Han, D.W.; vom Bruch, H.; Moritz, S.; Lijnzaad, P.; Altelaar, A.F.M.; Sameith, K.; Zaehres, H.; Heck, A.J.R.; Holstege, F.C.P.; Scholer, H.R.; Timmers, H.T.M.

Year: 2013

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/290810

Thesis Novel Approaches for Pluripotent Reprogramming

Weltner, Jere · 2018 · University of Helsinki (HELDA) · DOI

Full title: Novel Approaches for Pluripotent Reprogramming

Authors: Weltner, Jere

Year: 2018

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/237188

Thesis The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells

Chen, Chun-hang; 陳進鏗 · 2013 · University of Hong Kong · DOI

Full title: The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells

Authors: Chen, Chun-hang; 陳進鏗

Year: 2013

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/193063

Thesis Enhanced lineage reprogramming towards induced neural stem cells with re-engineered SOX17

Weng, Mingxi; 翁铭曦 · 2023 · University of Hong Kong · DOI

Full title: Enhanced lineage reprogramming towards induced neural stem cells with re-engineered SOX17

Authors: Weng, Mingxi; 翁铭曦

Year: 2023

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/323693

Thesis Induction of cells with osteo-chondrogenic potential by transcription factor-mediated reprogramming process

Wang, Yinxiang; 王胤祥 · 2015 · University of Hong Kong · DOI

Full title: Induction of cells with osteo-chondrogenic potential by transcription factor-mediated reprogramming process

Authors: Wang, Yinxiang; 王胤祥

Year: 2015

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/207993

Thesis Genomic instability in induced stem cells

Pasi, C. E.; Dereli-Öz, A.; Negrini, S. et al. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Genomic instability in induced stem cells

Authors: Pasi, C. E.; Dereli-Öz, A.; Negrini, S.; Friedli, M.; Fragola, G.; Lombardo, A.; Van Houwe, G.; Naldini, L.; Casola, S.; Testa, G.; Trono, D.; Pelicci, P. G.; Halazonetis, T. D.

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/64361

Thesis Decoding single-cell heterogeneity and plasticity

Liu, Wangjie · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Decoding single-cell heterogeneity and plasticity

Authors: Liu, Wangjie

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/255121

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Soren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin Y.; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David J.; Gorbunova, Vera; de Grey, Aubrey; He, Wei-Wu; Hoeijmakers, Jan; Hoffmann, Eva; Horvath, Steve; Houtkooper, Riekelt H.; Jensen, Majken K.; Jensen, Martin Borch; Kane, Alice; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian; Karsenty, Gerard; Lamming, Dudley W.; Lee, Kai-Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura; Osborne, Brenna; Pak, Heidi H.; Parkhitko, Andrey; Raimundo, Nuno; Rando, Thomas A.; Rasmussen, Lene Juel; Reis, Carolina; Riedel, Christian G.; Franco-Romero, Anais; Schumacher, Bjoern; Sinclair, David A.; Suh, Yousin; Taub, Pam R.; Toiber, Debra; Treebak, Jonas T.; Valenzano, Dario Riccardo; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/179431

Thesis Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Schorderet, Patrick · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Authors: Schorderet, Patrick

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/40900

Thesis Epigenetic memory in induced pluripotent stem cells

Kim, K.; Doi, A.; Wen, B. et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Epigenetic memory in induced pluripotent stem cells

Authors: Kim, K.; Doi, A.; Wen, B.; Ng, K.; Zhao, R.; Cahan, P.; Kim, J.; Aryee, M. J.; Ji, H.; Ehrlich, L. I. R.; Yabuuchi, A.; Takeuchi, A.; Cunniff, K. C.; Hongguang, H.; McKinney-Freeman, S.; Naveiras, O.; Yoon, T. J.; Irizarry, R. A.; Jung, N.; Seita, J.; Hanna, J.; Murakami, P.; Jaenisch, R.; Weissleder, R.; Orkin, S. H.; Weissman, I. L.; Feinberg, A. P.; Daley, G. Q.

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/102167

Thesis The Future Challenges for the Clinical Application of Reprogrammed Cells

Ana Belen Alvarez Palomo, JR · 2017 · University of Melbourne · DOI

Full title: The Future Challenges for the Clinical Application of Reprogrammed Cells

Authors: Ana Belen Alvarez Palomo, JR

Year: 2017

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/194263

Thesis NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, Hongbo; Ryu, Dongryeol; Wu, Yibo et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

Authors: Zhang, Hongbo; Ryu, Dongryeol; Wu, Yibo; Gariani, Karim; Wang, Xu; Luan, Peiling; D'Amico, Davide; Ropelle, Eduardo R; Lutolf, Matthias P; Aebersold, Ruedi; Schoonjans, Kristina; Menzies, Keir J; Auwerx, Johan

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/126595

Thesis Defined three-dimensional microenvironments boost induction of pluripotency

Caiazzo, Massimiliano; Okawa, Yuya; Ranga, Adrian et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Defined three-dimensional microenvironments boost induction of pluripotency

Authors: Caiazzo, Massimiliano; Okawa, Yuya; Ranga, Adrian; Piersigilli, Alessandra; Tabata, Yoji; Lutolf, Matthias P.

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/125287

Thesis Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Slamecka, Jaroslav; Salimova, Lilia; Mcclellan, Steven et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Authors: Slamecka, Jaroslav; Salimova, Lilia; Mcclellan, Steven; Van Kelle, Mathieu; Kehl, Debora; Laurini, Javier; Cinelli, Paolo; Owen, Laurie; Hoerstrup, Simon P.; Weber, Benedikt

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/125436

Thesis Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Friedli, Marc; Turelli, Priscilla; Kapopoulou, Adamandia et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

Authors: Friedli, Marc; Turelli, Priscilla; Kapopoulou, Adamandia; Rauwel, Benjamin; Castro-Díaz, Nathaly; Rowe, Helen M; Ecco, Gabriela; Unzu, Carmen; Planet, Evarist; Lombardo, Angelo; Mangeat, Bastien; Wildhaber, Barbara E; Naldini, Luigi; Trono, Didier

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/104193

Thesis Neuronal reprogramming for tissue repair and neuroregeneration

Liou, RHC; Edwards, TL; Martin, KR et al. · 2020 · University of Melbourne · DOI

Full title: Neuronal reprogramming for tissue repair and neuroregeneration

Authors: Liou, RHC; Edwards, TL; Martin, KR; Wong, RCB

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/244479

Thesis The Effects of Nuclear Reprogramming on Mitochondrial DNA Replication

Kelly, RDW; Sumer, H; McKenzie, M et al. · 2018 · University of Melbourne · DOI

Full title: The Effects of Nuclear Reprogramming on Mitochondrial DNA Replication

Authors: Kelly, RDW; Sumer, H; McKenzie, M; Facucho-Oliveira, J; Trounce, IA; Verma, PJ; St. John, JC

Year: 2018

Venue: University of Melbourne

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000314536200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c

Thesis Senescence in tissue samples of humans with age-related diseases: A systematic review

Tuttle, CSL; Luesken, SWM; Waaijer, MEC et al. · 2021 · University of Melbourne · DOI

Full title: Senescence in tissue samples of humans with age-related diseases: A systematic review

Authors: Tuttle, CSL; Luesken, SWM; Waaijer, MEC; Maier, AB

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/281656

Thesis Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence

Guan, L; Crasta, KC; Maier, AB · 2022 · University of Melbourne · DOI

Full title: Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence

Authors: Guan, L; Crasta, KC; Maier, AB

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/310738

Thesis Changing Fate: Reprogramming Cells via Engineered Nanoscale Delivery Materials

Soltani Dehnavi, S; Eivazi Zadeh, Z; Harvey, AR et al. · 2022 · University of Melbourne · DOI

Full title: Changing Fate: Reprogramming Cells via Engineered Nanoscale Delivery Materials

Authors: Soltani Dehnavi, S; Eivazi Zadeh, Z; Harvey, AR; Voelcker, NH; Parish, CL; Williams, RJ; Elnathan, R; Nisbet, DR

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/310590

Thesis The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening.

Patrick, R; Naval-Sanchez, M; Deshpande, N et al. · 2024 · University of Melbourne · DOI

Full title: The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening.

Authors: Patrick, R; Naval-Sanchez, M; Deshpande, N; Huang, Y; Zhang, J; Chen, X; Yang, Y; Tiwari, K; Esmaeili, M; Tran, M; Mohamed, AR; Wang, B; Xia, D; Ma, J; Bayliss, J; Wong, K; Hun, ML; Sun, X; Cao, B; Cottle, DL; Catterall, T; Barzilai-Tutsch, H; Troskie, R-L; Chen, Z; Wise, AF; Saini, S; Soe, YM; Kumari, S; Sweet, MJ; Thomas, HE; Smyth, IM; Fletcher, AL; Knoblich, K; Watt, MJ; Alhomrani, M; Alsanie, W; Quinn, KM; Merson, TD; Chidgey, AP; Ricardo, SD; Yu, D; Jardé, T; Cheetham, SW; Marcelle, C; Nilsson, SK; Nguyen, Q; White, MD; Nefzger, CM

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349477

Thesis The Business of Anti-Aging Science

de Magalhaes, Joao Pedro; Stevens, Michael; Thornton, Daniel · 2017 · University of Liverpool · DOI

Full title: The Business of Anti-Aging Science

Authors: de Magalhaes, Joao Pedro; Stevens, Michael; Thornton, Daniel

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3008938/1/aging_business_TrendsBiotech_revised_final.docx

Thesis A multidimensional systems biology analysis of cellular senescence in aging and disease

Avelar, Roberto A; Ortega, Javier Gomez; Tacutu, Robi et al. · 2020 · University of Liverpool · DOI

Full title: A multidimensional systems biology analysis of cellular senescence in aging and disease

Authors: Avelar, Roberto A; Ortega, Javier Gomez; Tacutu, Robi; Tyler, Eleanor J; Bennett, Dominic; Binetti, Paolo; Budovsky, Arie; Chatsirisupachai, Kasit; Johnson, Emily; Murray, Alex; Shields, Samuel; Tejada-Martinez, Daniela; Thornton, Daniel; Fraifeld, Vadim E; Bishops, Cleo L; de Magalhaes, Joao Pedro

Year: 2020

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3082666

Thesis Stress, cell senescence and organismal ageing

de Magalhaes, Joao Pedro; Passos, Joao F · 2018 · University of Liverpool · DOI

Full title: Stress, cell senescence and organismal ageing

Authors: de Magalhaes, Joao Pedro; Passos, Joao F

Year: 2018

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3008468

Thesis Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex.

Kleger, A; Mahaddalkar, PU; Katz, SF et al. · 2012 · Technical University of Munich (TUM) · DOI

Full title: Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex.

Authors: Kleger, A;Mahaddalkar, PU;Katz, SF;Lechel, A;Joo, JY;Loya, K;Lin, Q;Hartmann, D;Liebau, S;Kraus, JM;Cantz, T;Kestler, HA;Zaehres, H;Schöler, H;Rudolph, KL

Year: 2012

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1181194

Thesis Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

Vidović, Tinka; Ewald, Collin; id_orcid0000-0003-1166-4171 · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

Authors: Vidović, Tinka; Ewald, Collin; id_orcid0000-0003-1166-4171

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/596283

Thesis Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging

Braunger, Jana M.; Cammarata, Louis V.; Sornapudi, Trinadha Rao et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging

Authors: Braunger, Jana M.; Cammarata, Louis V.; Sornapudi, Trinadha Rao; Uhler, Caroline; Shivashankar, G.V.

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/648779

Thesis ATAC-clock: An aging clock based on chromatin accessibility

Morandini, Francesco; Rechsteiner, Cheyenne; Perez, Kevin et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: ATAC-clock: An aging clock based on chromatin accessibility

Authors: Morandini, Francesco; Rechsteiner, Cheyenne; Perez, Kevin; Praz, Viviane; Garcia, Guillermo Lopez; Hinte, Laura; id_orcid0000-0002-4226-0009; von Meyenn, Ferdinand; id_orcid0000-0002-4226-0009; Ocampo, Alejandro

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/647245

Thesis Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing

Roy, Bibhas; Pekec, Tina; Yuan, Luezhen et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing

Authors: Roy, Bibhas; Pekec, Tina; Yuan, Luezhen; Shivashankar, G.V.

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/646298

Thesis Comparative analysis of mouse strains for in vivo induction of reprogramming factors

Picó, Sara; Vílchez-Acosta, Alba; Agostinho de Sousa, João Pedro et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Comparative analysis of mouse strains for in vivo induction of reprogramming factors

Authors: Picó, Sara; Vílchez-Acosta, Alba; Agostinho de Sousa, João Pedro; id_orcid0000-0001-8124-6624; Maza, del Carmen María; Mrabti, Calida; Parras, Alberto; Desdín-Micó, Gabriela; Maroun, Céline Yacoub; Branchina, Clémence; von Meyenn, Ferdinand; id_orcid0000-0001-8124-6624; Ocampo, Alejandro

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/742779

Thesis Programming human cell fate: overcoming challenges and unlocking potential through technological breakthroughs

Lin, Hsiu-Chuan; Makhlouf, Aly; Vazquez Echegaray, Camila et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Programming human cell fate: overcoming challenges and unlocking potential through technological breakthroughs

Authors: Lin, Hsiu-Chuan; Makhlouf, Aly; Vazquez Echegaray, Camila; Zawada, Dorota; Simões, Filipa

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/649079

Thesis Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

Knufinke, Marie; MacArthur, Michael R.; Ewald, Collin et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

Authors: Knufinke, Marie; MacArthur, Michael R.; Ewald, Collin; id_orcid0000-0003-1166-4171; Mitchell, Sarah J.

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/641207

Thesis Single-cell genomic profiling to study regeneration

Maynard, Ashley; id_orcid0000-0002-3588-3080; Soretić, Mateja et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Single-cell genomic profiling to study regeneration

Authors: Maynard, Ashley; id_orcid0000-0002-3588-3080; Soretić, Mateja; Treutlein, Barbara; id_orcid0000-0002-3588-3080

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/686189

Thesis Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation

Weber, Fabienne A; Bartolomei, Giody; Hottiger, Michael O et al. · 2013 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation

Authors: Weber, Fabienne A; Bartolomei, Giody; Hottiger, Michael O; Cinelli, Paolo

Year: 2013

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/99467

Thesis Reprogramming of rat embryonic fibroblasts derived from different rat strains and function of Pramel7 in reprogramming

Zumthor, Jon Paulin · 2010 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Reprogramming of rat embryonic fibroblasts derived from different rat strains and function of Pramel7 in reprogramming

Authors: Zumthor, Jon Paulin

Year: 2010

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/152599

Thesis Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts

Sornapudi, Trinadha Rao; Yuan, Luezhen; Braunger, Jana M. et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts

Authors: Sornapudi, Trinadha Rao; Yuan, Luezhen; Braunger, Jana M.; Uhler, Caroline; Shivashankar, G.V.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/713619

Thesis Single-Cell Resolution Mechanistic Analyses of Direct Lineage Reprogramming

Guo, Chuner · 2021 · Washington University in St. Louis · DOI

Full title: Single-Cell Resolution Mechanistic Analyses of Direct Lineage Reprogramming

Authors: Guo, Chuner

Year: 2021

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/2421

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Paper

Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Xueke, Zhou; Hong, Yimei; Zhang, Hao et al. · 2020

Full title: Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Authors: Xueke, Zhou; Hong, Yimei; Zhang, Hao; Li, Xin

DOI: https://doi.org/10.3389/fcell.2020.00364

Paper

The interplay of cellular senescence and reprogramming shapes the biological landscape of aging and cancer revealing novel therapeutic avenues.

Ding, Fuan; Yu, Ying; Zhao, Jiangqi et al. · 2025

Full title: The interplay of cellular senescence and reprogramming shapes the biological landscape of aging and cancer revealing novel therapeutic avenues.

Authors: Ding, Fuan; Yu, Ying; Zhao, Jiangqi; Wei, Shibo; Zhang, Yan; Han, Jung Ho; Li, Zhuo; Jiang, Hong-Bo; Ryu, Dongryeol; Cho, Minkyoung; Bae, Sung-Jin; Park, Wonyoung; Ha, Ki-Tae; Gao, Bo

DOI: https://doi.org/10.3389/fcell.2025.1593096

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Lipchina, Inna; Elkabetz, Yechiel; Hafner, Markus et al. · 2011

Full title: Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response

Authors: Lipchina, Inna; Elkabetz, Yechiel; Hafner, Markus; Sheridan, Robert P.; Mihailović, Aleksandra; Tuschl, Thomas; Sander, Chris; Studer, Lorenz; Betel, Doron

DOI: https://doi.org/10.1101/gad.17221311

Paper

Context-specific α-to-β-cell reprogramming by forced Pdx1 expression

Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F. et al. · 2011

Full title: Context-specific α-to-β-cell reprogramming by forced Pdx1 expression

Authors: Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F.; Herrera, Pedro L.; Wright, Christopher V.E.

DOI: https://doi.org/10.1101/gad.16875711

Paper

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

Johnson, Nicole C; Dillard, Miriam E.; Bałuk, Peter et al. · 2008

Full title: Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

Authors: Johnson, Nicole C; Dillard, Miriam E.; Bałuk, Peter; McDonald, Donald M.; Harvey, Natasha L.; Frase, Sharon; Oliver, Guillermo

DOI: https://doi.org/10.1101/gad.1727208

Paper

Extension of chronological life span in yeast by decreased TOR pathway signaling

Powers, Ryan; Kaeberlein, Matt; Caldwell, Seth D. et al. · 2006

Full title: Extension of chronological life span in yeast by decreased TOR pathway signaling

Authors: Powers, Ryan; Kaeberlein, Matt; Caldwell, Seth D.; Kennedy, Brian K.; Fields, Stanley

DOI: https://doi.org/10.1101/gad.1381406

Paper

A role for mitotic bookmarking of SOX2 in pluripotency and differentiation

Deluz, Cédric; Friman, Elias T.; Strebinger, Daniel et al. · 2016

Full title: A role for mitotic bookmarking of SOX2 in pluripotency and differentiation

Authors: Deluz, Cédric; Friman, Elias T.; Strebinger, Daniel; Benke, Alexander; Raccaud, Mahé; Callegari, Andrea; Leleu, Marion; Manley, Suliana; Suter, David M.

DOI: https://doi.org/10.1101/gad.289256.116

Paper

Robust cellular reprogramming occurs spontaneously during liver regeneration

Yanger, Kilangsungla; Zong, Yiwei; Maggs, Lara R. et al. · 2013

Full title: Robust cellular reprogramming occurs spontaneously during liver regeneration

Authors: Yanger, Kilangsungla; Zong, Yiwei; Maggs, Lara R.; Shapira, Suzanne N.; Maddipati, Ravi; Aiello, Nicole M.; Thung, Swan N.; Wells, Rebecca G.; Greenbaum, Linda E.; Stanger, Ben Z.

DOI: https://doi.org/10.1101/gad.207803.112

Paper

Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis

Hiratani, Ichiro; Ryba, Tyrone; Itoh, Mari et al. · 2009

Full title: Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis

DOI: https://doi.org/10.1101/gr.099796.109

Paper

Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

MacNeil, Lesley T.; Walhout, Albertha J.M. · 2011

Full title: Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

Authors: MacNeil, Lesley T.; Walhout, Albertha J.M.

DOI: https://doi.org/10.1101/gr.097378.109

Paper

Advances in stem cell therapy for spinal cord injury

Mothe, Andrea J.; Tator, Charles H. · 2012

Full title: Advances in stem cell therapy for spinal cord injury

Authors: Mothe, Andrea J.; Tator, Charles H.

DOI: https://doi.org/10.1172/jci64124

Paper

Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

Espejel, Silvia; Roll, Garrett R.; McLaughlin, K. John et al. · 2010

Full title: Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

Authors: Espejel, Silvia; Roll, Garrett R.; McLaughlin, K. John; Lee, Andrew Y.; Zhang, Jenny Y.; Laird, Diana J.; Okita, Keisuke; Yamanaka, Shinya; Willenbring, Holger

DOI: https://doi.org/10.1172/jci43267

Paper

Cancer stem cells in the development of liver cancer

Yamashita, Taro; Wang, Xin Wei · 2013

Full title: Cancer stem cells in the development of liver cancer

Authors: Yamashita, Taro; Wang, Xin Wei

DOI: https://doi.org/10.1172/jci66024

Thesis

Simulating Direct Conversion of Adult Fibroblasts to Neurons

Eriksson, Joakim · 2017

Full title: Simulating Direct Conversion of Adult Fibroblasts to Neurons

Authors: Eriksson, Joakim

DOI: http://lup.lub.lu.se/student-papers/record/8901569

Thesis

Cell reprogramming as a way to produce new functional neurons

Pereira, Maria · 2017

Full title: Cell reprogramming as a way to produce new functional neurons

Authors: Pereira, Maria

DOI: https://lup.lub.lu.se/record/2abf7f80-22b7-403a-bd36-d28450ffddac

Thesis

Improving Healthspan through Patient-Derived Artificial Organs from Induced Pluripotent Stem Cells and Two-Photon Polymerization

Espenshade, Connor · 2023

Full title: Improving Healthspan through Patient-Derived Artificial Organs from Induced Pluripotent Stem Cells and Two-Photon Polymerization

Authors: Espenshade, Connor

DOI: https://repository.upenn.edu/handle/20.500.14332/45892

Thesis

Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

Humphreys, Tom; Weiser, Keith; Arimoto, Asuka et al. · 2022

Full title: Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

DOI: https://oist.repo.nii.ac.jp/record/2595/files/fevo-10-769433.pdf

Thesis

Modelling conversion of adult skin cells to neurons

Drugge, Viktor · 2018

Full title: Modelling conversion of adult skin cells to neurons

Authors: Drugge, Viktor

DOI: http://lup.lub.lu.se/student-papers/record/8940614

Thesis

CDKN2B Upregulation Prevents Teratoma Formation in Multipotent Fibromodulin-Reprogrammed Cells

Zheng, Zhong; Li, Chenshuang; Ha, Pin et al. · 2023

Full title: CDKN2B Upregulation Prevents Teratoma Formation in Multipotent Fibromodulin-Reprogrammed Cells

DOI: https://repository.upenn.edu/handle/20.500.14332/9234

Thesis

Direct Reprogramming—The Future of Cardiac Regeneration?

Doppler, Stefanie; Deutsch, Marcus-André; Lange, Rüdiger et al. · 2015

Full title: Direct Reprogramming—The Future of Cardiac Regeneration?

Authors: Doppler, Stefanie;Deutsch, Marcus-André;Lange, Rüdiger;Krane, Markus

DOI: https://mediatum.ub.tum.de/1323689

Thesis

Acquisition and maintenance of pluripotency are influenced by fibroblast growth factor, leukemia inhibitory factor, and 2i in bovine-induced pluripotent stem cells

Botigelli, Ramon Cesar [UNESP]; Pieri, Naira Carolina Godoy; Bessi, Brendon William et al. · 2023

Full title: Acquisition and maintenance of pluripotency are influenced by fibroblast growth factor, leukemia inhibitory factor, and 2i in bovine-induced pluripotent stem cells

DOI: http://dx.doi.org/10.3389/fcell.2022.938709

Thesis

Células tronco pluripotentes induzidas: importância e estado da arte da pesquisa brasileira

Santos Junior, Roque Silva dos [UNESP] · 2023

Full title: Células tronco pluripotentes induzidas: importância e estado da arte da pesquisa brasileira

Authors: Santos Junior, Roque Silva dos [UNESP]

DOI: http://hdl.handle.net/11449/239166

Thesis

Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks

Benevento, Marco; Tonge, Peter D; Puri, Mira C et al. · 2014

Full title: Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks

Authors: Benevento, Marco; Tonge, Peter D; Puri, Mira C; Hussein, Samer M I; Cloonan, Nicole; Wood, David L; Grimmond, Sean M; Nagy, Andras; Munoz, Javier; Heck, Albert J R

DOI: https://dspace.library.uu.nl/handle/1874/304285

Thesis

Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53

Dirac, A.M.G.; Bernards, R.A. · 2003

Full title: Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53

Authors: Dirac, A.M.G.; Bernards, R.A.

DOI: https://dspace.library.uu.nl/handle/1874/17754

Thesis

Small RNA changes en route to distinct cellular states of induced pluripotency

Clancy, Jennifer L; Patel, Hardip R; Hussein, Samer M I et al. · 2014

Full title: Small RNA changes en route to distinct cellular states of induced pluripotency

DOI: https://dspace.library.uu.nl/handle/1874/304286

Thesis

Resilience to aging in the regeneration-capable flatworm Macrostomum lignano

Mouton, Stijn; Grudniewska, Magda; Glazenburg, Lisa et al. · 2018

Full title: Resilience to aging in the regeneration-capable flatworm Macrostomum lignano

Authors: Mouton, Stijn; Grudniewska, Magda; Glazenburg, Lisa; Guryev, Victor; Berezikov, Eugene

DOI: https://dspace.library.uu.nl/handle/1874/369059

Thesis

MicroRNA Roles in Cell Reprogramming Mechanisms

Pascale, Emilia; Caiazza, Carmen; Paladino, Martina et al. · 2022

Full title: MicroRNA Roles in Cell Reprogramming Mechanisms

Authors: Pascale, Emilia; Caiazza, Carmen; Paladino, Martina; Parisi, Silvia; Passaro, Fabiana; Caiazzo, Massimiliano

DOI: https://dspace.library.uu.nl/handle/1874/422225

Thesis

Hepatocyte-like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers

Chen, Chen; Pla-Palacín, Iris; Baptista, Pedro M. et al. · 2018

Full title: Hepatocyte-like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers

Authors: Chen, Chen; Pla-Palacín, Iris; Baptista, Pedro M.; Shang, Peng; Oosterhoff, Loes A.; van Wolferen, Monique E.; Penning, Louis C.; Geijsen, Niels; Spee, Bart

DOI: https://dspace.library.uu.nl/handle/1874/377295

Thesis

Direct Cell Conversion of Somatic Cells into Dopamine Neurons: Achievements and Perspectives

Aversano, Simona; Palladino, Renata; Caiazzo, Massimiliano · 2022

Full title: Direct Cell Conversion of Somatic Cells into Dopamine Neurons: Achievements and Perspectives

Authors: Aversano, Simona; Palladino, Renata; Caiazzo, Massimiliano

DOI: https://dspace.library.uu.nl/handle/1874/424164

Thesis

Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

Aversano, Simona; Caiazza, Carmen; Caiazzo, Massimiliano · 2022

Full title: Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

Authors: Aversano, Simona; Caiazza, Carmen; Caiazzo, Massimiliano

DOI: https://dspace.library.uu.nl/handle/1874/425930

Thesis

Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species

Fang, Juntao; Yang, Qiangbing; Maas, Renée G C et al. · 2024

Full title: Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species

DOI: https://dspace.library.uu.nl/handle/1874/451082

Thesis

Molecular Control of Induced Pluripotency

Theunissen, Thorold W.; Jaenisch, Rudolf · 2016

Full title: Molecular Control of Induced Pluripotency

Authors: Theunissen, Thorold W.; Jaenisch, Rudolf

DOI: http://hdl.handle.net/1721.1/104363

Thesis

RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming

Toh, Cheng-Xu Delon; Chan, Jun-Wei; Chong, Zheng-Shan et al. · 2016

Full title: RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming

DOI: http://hdl.handle.net/1721.1/103550

Thesis

The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

Buganim, Yosef; Markoulaki, Styliani; van Wietmarschen, Niek et al. · 2017

Full title: The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

DOI: http://hdl.handle.net/1721.1/109508

Thesis

Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes

Iacovides, Demetris; Rizki, Gizem; Lapathitis, Georgios et al. · 2016

Full title: Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes

Authors: Iacovides, Demetris; Rizki, Gizem; Lapathitis, Georgios; Strati, Katerina

DOI: http://hdl.handle.net/1721.1/103916

Thesis

ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors

Skamagki, Maria; Correia, Cristina; Yeung, Percy et al. · 2018

Full title: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors

DOI: http://hdl.handle.net/1721.1/117588

Thesis

A dynamical model for the low efficiency of induced pluripotent stem cell reprogramming

Abdallah, Hussein M.; Qian, Yili; Del Vecchio, Domitilla · 2017

Full title: A dynamical model for the low efficiency of induced pluripotent stem cell reprogramming

Authors: Abdallah, Hussein M.; Qian, Yili; Del Vecchio, Domitilla

DOI: http://hdl.handle.net/1721.1/107844

Thesis

Editing DNA Methylation in the Mammalian Genome

Liu, X. Shawn; Wu, Hao; Ji, Xiong et al. · 2018

Full title: Editing DNA Methylation in the Mammalian Genome

DOI: http://hdl.handle.net/1721.1/116619

Thesis

Engineering cell fate: Applying synthetic biology to cellular reprogramming

Wang, Nathan B; Beitz, Adam M; Galloway, Katie · 2022

Full title: Engineering cell fate: Applying synthetic biology to cellular reprogramming

Authors: Wang, Nathan B; Beitz, Adam M; Galloway, Katie

DOI: https://hdl.handle.net/1721.1/133290.2

Thesis

Transcriptomic reprogramming for neuronal age reversal

Plesa, Alexandru M.; Shadpour, Michael; Boyden, Ed et al. · 2023

Full title: Transcriptomic reprogramming for neuronal age reversal

Authors: Plesa, Alexandru M.; Shadpour, Michael; Boyden, Ed; Church, George M.

DOI: https://hdl.handle.net/1721.1/150336

Thesis

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

Cacchiarelli, Davide; Trapnell, Cole; Ziller, Michael J. et al. · 2017

Full title: Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

DOI: http://hdl.handle.net/1721.1/106526

Thesis

A model for genetic and epigenetic regulatory networks identifies rare for transcription factor induced pluripotency

Artyomov, Maxim N.; Meissner, Alexander; Chakraborty, Arup K. · 2010

Full title: A model for genetic and epigenetic regulatory networks identifies rare for transcription factor induced pluripotency

Authors: Artyomov, Maxim N.; Meissner, Alexander; Chakraborty, Arup K.

DOI: http://hdl.handle.net/1721.1/57580

Thesis

Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Xing, QR; El Farran, CA; Gautam, P et al. · 2021

Full title: Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Authors: Xing, QR; El Farran, CA; Gautam, P; Chuah, YS; Warrier, T; Toh, CXD; Kang, NY; Sugii, S; Chang, YT; Xu, J; Collins, JJ; Daley, GQ; Li, H; Zhang, LF; Loh, YH

DOI: https://hdl.handle.net/1721.1/133493

Thesis

Reprogramming human somatic cells to pluripotency using RNA

Angel, Matthew (Matthew M.) · 2012

Full title: Reprogramming human somatic cells to pluripotency using RNA

Authors: Angel, Matthew (Matthew M.)

DOI: http://hdl.handle.net/1721.1/70786

Thesis

Pan-Src Family Kinase Inhibitors Replace Sox2 during the Direct Reprogramming of Somatic Cells

Staerk, Judith; Lyssiotis, Costas A.; Medeiro, Lea A. et al. · 2012

Full title: Pan-Src Family Kinase Inhibitors Replace Sox2 during the Direct Reprogramming of Somatic Cells

DOI: http://hdl.handle.net/1721.1/73479

Thesis

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Kim, Jongpil; Lengner, Christopher J.; Kirak, Oktay et al. · 2012

Full title: Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

DOI: http://hdl.handle.net/1721.1/73480

Thesis

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Hanna, Jacob; Markoulaki, Styliani; Mathur, Divya et al. · 2010

Full title: Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

DOI: http://hdl.handle.net/1721.1/52555

Thesis

Chromatin-modifying enzymes as modulators of reprogramming

Onder, Tamer T.; Kara, Nergis; Cherry, Anne et al. · 2014

Full title: Chromatin-modifying enzymes as modulators of reprogramming

DOI: http://hdl.handle.net/1721.1/84482

Thesis

Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm

Jaenisch, Rudolf · 2014

Full title: Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm

Authors: Jaenisch, Rudolf

DOI: http://hdl.handle.net/1721.1/84640

Thesis

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Buganim, Yosef; Faddah, Dina A.; Itskovich, Elena et al. · 2014

Full title: Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

DOI: http://hdl.handle.net/1721.1/91944

Thesis

Direct cell reprogramming is a stochastic process amenable to acceleration

Jaenisch, Rudolf; Lengner, Christopher J.; van Oudenaarden, Alexander et al. · 2010

Full title: Direct cell reprogramming is a stochastic process amenable to acceleration

Authors: Jaenisch, Rudolf; Lengner, Christopher J.; van Oudenaarden, Alexander; Van Zon, Jeroen Sebastiaan; Pando, Bernardo Fabian; Saha, Krishanu; Hanna, Jacob; Creyghton, Menno P.

DOI: http://hdl.handle.net/1721.1/58480

Thesis

A stochastic model dissects cell states in biological transition processes

Armond, Jonathan W.; Saha, Krishanu; Rana, Anas A. et al. · 2014

Full title: A stochastic model dissects cell states in biological transition processes

Authors: Armond, Jonathan W.; Saha, Krishanu; Rana, Anas A.; Oates, Chris J.; Jaenisch, Rudolf; Nicodemi, Mario; Mukherjee, Sach

DOI: http://hdl.handle.net/1721.1/88212

Thesis

Epigenetic memory in induced pluripotent stem cells

Kim, K.; Doi, A.; Wen, B. et al. · 2012

Full title: Epigenetic memory in induced pluripotent stem cells

DOI: http://hdl.handle.net/1721.1/73941

Thesis

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Soldner, Frank; Hockemeyer, Dirk; Beard, Caroline et al. · 2015

Full title: Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

DOI: http://hdl.handle.net/1721.1/96268

Thesis

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Unternaehrer, Juli J.; Zhao, Rui; Kim, Kitai et al. · 2015

Full title: The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

DOI: http://hdl.handle.net/1721.1/96337

Thesis

Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues

Hanna, Jacob; Saha, Krishanu; Jaenisch, Rudolf · 2015

Full title: Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues

Authors: Hanna, Jacob; Saha, Krishanu; Jaenisch, Rudolf

DOI: http://hdl.handle.net/1721.1/96107

Thesis

Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Cassady, John P.; D’Alessio, Ana C.; Sarkar, Sovan et al. · 2015

Full title: Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Authors: Cassady, John P.; D’Alessio, Ana C.; Sarkar, Sovan; Fan, Zi Peng; Ganz, Kibibi; Roessler, Reinhard; Sur, Mriganka; Young, Richard A.; Jaenisch, Rudolf; Dani, Vardhan; Young, Richard A.

DOI: http://hdl.handle.net/1721.1/96277

Thesis

Modeling Stem Cell Induction Processes

Gracio, Filipe; Cabral, Joaquim M. S.; Tidor, Bruce · 2013

Full title: Modeling Stem Cell Induction Processes

Authors: Gracio, Filipe; Cabral, Joaquim M. S.; Tidor, Bruce

DOI: http://hdl.handle.net/1721.1/79416

Thesis

Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

Carey, Bryce W.; Markoulaki, Styliani; Hanna, Jacob et al. · 2015

Full title: Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

DOI: http://hdl.handle.net/1721.1/95810

Thesis

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Ring, Karen Lee · 2012

Full title: Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Authors: Ring, Karen Lee

DOI: https://escholarship.org/uc/item/359616z5

Thesis

Reprogramming scleroderma-specific and normal fibroblast gene subsets using single versus multiple transcription factors

Van Buren, Tyler Martin · 2010

Full title: Reprogramming scleroderma-specific and normal fibroblast gene subsets using single versus multiple transcription factors

Authors: Van Buren, Tyler Martin

DOI: https://escholarship.org/uc/item/0r08856j

Thesis

Multiple Transcription Factor Perturbations Rejuvenate Aged Human Skin Fibroblasts with a Conserved Transcriptional Signature

Sengstack, Janine · 2023

Full title: Multiple Transcription Factor Perturbations Rejuvenate Aged Human Skin Fibroblasts with a Conserved Transcriptional Signature

Authors: Sengstack, Janine

DOI: https://escholarship.org/uc/item/6s9064q0

Thesis

Designing and characterizing artificial transcription factors targeting critical embryonic stem cell self- renewal and pluripotency genes in somatic cells

Yang, Steven · 2009

Full title: Designing and characterizing artificial transcription factors targeting critical embryonic stem cell self- renewal and pluripotency genes in somatic cells

Authors: Yang, Steven

DOI: https://escholarship.org/uc/item/3tk6c44c

Thesis

Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine

Yeola, Avani; Subramanian, Shruthi; Oliver, Rema A et al. · 2021

Full title: Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine

DOI: http://hdl.handle.net/1959.4/unsworks_75132

Thesis

A Combined Epigenetic and Non-Genetic Approach for Reprogramming Human Somatic Cells

Han, J; Sachdev, P; https://orcid.org/0000-0002-9595-3220 et al. · 2010

Full title: A Combined Epigenetic and Non-Genetic Approach for Reprogramming Human Somatic Cells

Authors: Han, J; Sachdev, P ; https://orcid.org/0000-0002-9595-3220; Sidhu, K

DOI: http://hdl.handle.net/1959.4/unsworks_38308

Thesis

H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

Hörmanseder, E; Simeone, A; Allen, GE et al. · 2017

Full title: H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

Authors: Hörmanseder, E; Simeone, A; Allen, GE; Bradshaw, CR; Figlmüller, M; Gurdon, J; Jullien, J

DOI: https://www.repository.cam.ac.uk/handle/1810/264440

Thesis

Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.

Miyamoto, Kei; Nguyen, Khoi T; Allen, George E et al. · 2018

Full title: Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.

Authors: Miyamoto, Kei; Nguyen, Khoi T; Allen, George E; Jullien, Jerome; Kumar, Dinesh; Otani, Tomoki; Bradshaw, Charles R; Livesey, Frederick J; Kellis, Manolis; Gurdon, John B

DOI: https://www.repository.cam.ac.uk/handle/1810/283552

Thesis

Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming.

Yang, Jian; Rajan, Sandeep S; Friedrich, Mathias J et al. · 2019

Full title: Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming.

Authors: Yang, Jian; Rajan, Sandeep S; Friedrich, Mathias J; Lan, Guocheng; Zou, Xiangang; Ponstingl, Hannes; Garyfallos, Dimitrios A; Liu, Pentao; Bradley, Allan; Metzakopian, Emmanouil

DOI: https://www.repository.cam.ac.uk/handle/1810/289965

Thesis

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

Drouin-Ouellet, Janelle; Lau, Shong; Brattås, Per Ludvik et al. · 2017

Full title: REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

DOI: https://www.repository.cam.ac.uk/handle/1810/269725

Thesis

Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

Stricker, SH; Feber, A; Engström, PG et al. · 2019

Full title: Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

Authors: Stricker, SH; Feber, A; Engström, PG; Carén, H; Kurian, KM; Takashima, Y; Watts, C; Way, M; Dirks, P; Bertone, P; Smith, A; Beck, S; Pollard, SM

DOI: https://www.repository.cam.ac.uk/handle/1810/295900

Thesis

Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Liou, Roxanne Hsiang-Chi; Edwards, Thomas L.; Martin, Keith R. et al. · 2020

Full title: Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Authors: Liou, Roxanne Hsiang-Chi; Edwards, Thomas L.; Martin, Keith R.; Wong, Raymond Ching-Bong

DOI: https://www.repository.cam.ac.uk/handle/1810/306895

Thesis

Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges.

Gam, Rihab; Sung, Minkyung; Prasad Pandurangan, Arun · 2019

Full title: Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges.

Authors: Gam, Rihab; Sung, Minkyung; Prasad Pandurangan, Arun

DOI: https://www.repository.cam.ac.uk/handle/1810/297537

Thesis

Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.

Martin-Herranz, Daniel E; Aref-Eshghi, Erfan; Bonder, Marc Jan et al. · 2020

Full title: Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.

Authors: Martin-Herranz, Daniel E; Aref-Eshghi, Erfan; Bonder, Marc Jan; Stubbs, Thomas M; Choufani, Sanaa; Weksberg, Rosanna; Stegle, Oliver; Sadikovic, Bekim; Reik, Wolf; Thornton, Janet M

DOI: https://www.repository.cam.ac.uk/handle/1810/309125

Thesis

Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle et al. · 2021

Full title: Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.

Authors: Bruzelius, Andreas; Kidnapillai, Srisaiyini; Drouin-Ouellet, Janelle; Stoker, Tom; Barker, Roger; Rylander Ottosson, Daniella

DOI: https://www.repository.cam.ac.uk/handle/1810/331334

Thesis

Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Gill, Diljeet; Parry, Aled; Santos, Fátima et al. · 2022

Full title: Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.

Authors: Gill, Diljeet; Parry, Aled; Santos, Fátima; Okkenhaug, Hanneke; Todd, Christopher D; Hernando-Herraez, Irene; Stubbs, Thomas M; Milagre, Inês; Reik, Wolf

DOI: https://www.repository.cam.ac.uk/handle/1810/336968

Thesis

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.

Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc et al. · 2022

Full title: Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.

DOI: https://www.repository.cam.ac.uk/handle/1810/334599

Thesis

Tumor suppressors inhibit reprogramming of African spiny mouse ( Acomys) fibroblasts to induced pluripotent stem cells.

Sandoval, Aaron Gabriel W; Maden, Malcolm; Bates, Lawrence E et al. · 2022

Full title: Tumor suppressors inhibit reprogramming of African spiny mouse ( Acomys) fibroblasts to induced pluripotent stem cells.

Authors: Sandoval, Aaron Gabriel W; Maden, Malcolm; Bates, Lawrence E; Silva, Jose CR

DOI: https://www.repository.cam.ac.uk/handle/1810/341708

Thesis

Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Wen, Ming-Hsuan; Triana, Hector Barbosa; Butler, Richard et al. · 2023

Full title: Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

DOI: https://www.repository.cam.ac.uk/handle/1810/361522

Thesis

Ageing versus developmental silencing: Answers from the epigenome.

Sadler, Kirsten C; Storer, Mekayla A; Bayin, N Sumru · 2025

Full title: Ageing versus developmental silencing: Answers from the epigenome.

Authors: Sadler, Kirsten C; Storer, Mekayla A; Bayin, N Sumru

DOI: https://www.repository.cam.ac.uk/handle/1810/388215

Thesis

Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.

Pedrosa, Pablo; Zhang, Zhenguang; Nuñez-Quintela, Victor et al. · 2024

Full title: Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.

DOI: https://www.repository.cam.ac.uk/handle/1810/376313

Thesis

Reprogramming of human cancer cells towards induced pluripotency as a tool to study the influence of epigenetic modifications on the tumor phenotype

Bernhardt, Mathias · 2015

Full title: Reprogramming of human cancer cells towards induced pluripotency as a tool to study the influence of epigenetic modifications on the tumor phenotype

Authors: Bernhardt, Mathias

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/18585/1/PhD%20thesis_MB_PDF_A_1A.pdf

Thesis

Partial reprogramming of melanoma cells mimics the phenotype switch and reveals SNAI3 as a novel invasion-associated marker

Knappe, Nathalie · 2015

Full title: Partial reprogramming of melanoma cells mimics the phenotype switch and reveals SNAI3 as a novel invasion-associated marker

Authors: Knappe, Nathalie

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/18723/1/DissertationNathalieKnappe.pdf.pdf

Thesis

Cellular metabolic profiles as potential indicators of variability in reprogramming potential

Hawrylyshyn, Eric · 2024

Full title: Cellular metabolic profiles as potential indicators of variability in reprogramming potential

Authors: Hawrylyshyn, Eric

DOI: https://hdl.handle.net/10214/28213

Thesis

Small Molecule Approaches for Targeting Signaling Networks in Cancer and Cellular Reprogramming

Dabiri, Yasamin · 2020

Full title: Small Molecule Approaches for Targeting Signaling Networks in Cancer and Cellular Reprogramming

Authors: Dabiri, Yasamin

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/28984/1/2020_Thesis_Dabiri.pdf

Thesis

DISSECTING THE REGULATORY LOGIC OF CELL FATE REPROGRAMMING THROUGH A MULTI-OMIC APPROACH

PANARIELLO, FRANCESCO · 2023

Full title: DISSECTING THE REGULATORY LOGIC OF CELL FATE REPROGRAMMING THROUGH A MULTI-OMIC APPROACH

Authors: PANARIELLO, FRANCESCO

DOI: https://hdl.handle.net/2434/1018340

Thesis

Reprogramming human cells using SMAR vectors and Potentiation of H-1PV oncolysis by Ledipasvir

Hartley, Anna · 2025

Full title: Reprogramming human cells using SMAR vectors and Potentiation of H-1PV oncolysis by Ledipasvir

Authors: Hartley, Anna

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34990/1/PhD_Thesis_Anna_Hartley.pdf

Thesis

AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Plesa, Alexandru · 2022

Full title: AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Authors: Plesa, Alexandru

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37373691

Thesis

Active repression of alternative cell fates safeguards hepatocyte identity

Lim, Bryce · 2025

Full title: Active repression of alternative cell fates safeguards hepatocyte identity

Authors: Lim, Bryce

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/33904/1/Active%20repression%20of%20alternative%20cell%20fates%20safeguards%20hepatocyte%20identity.pdf

Thesis

Elucidating variation in somatic cell lines that influence reprogramming potential

Toorani, Tahmineh · 2020

Full title: Elucidating variation in somatic cell lines that influence reprogramming potential

Authors: Toorani, Tahmineh

DOI: http://hdl.handle.net/10214/17945

Thesis

Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Griffin, Patrick T · 2023

Full title: Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Authors: Griffin, Patrick T

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375515

Thesis

Studying the Epigenetic Regulation of Stem Cell Aging and Rejuvenation

Gorelov, Rebecca · 2024

Full title: Studying the Epigenetic Regulation of Stem Cell Aging and Rejuvenation

Authors: Gorelov, Rebecca

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37379852

Thesis

Investigating molecular and regulatory boundaries of the pluripotent state

Sindhu-Bertrand, Camille Anne · 2018

Full title: Investigating molecular and regulatory boundaries of the pluripotent state

Authors: Sindhu-Bertrand, Camille Anne

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:37944941

Thesis

Deciphering the Molecular Basis of Cellular Reprogramming by Mass Spectrometry-based Proteomics

Benevento, M. · 2014

Full title: Deciphering the Molecular Basis of Cellular Reprogramming by Mass Spectrometry-based Proteomics

Authors: Benevento, M.

DOI: https://dspace.library.uu.nl/handle/1874/294765

Thesis

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Cleary, Brian Lowman; Lin, Stacie; Jaenisch, Rudolf et al. · 2020

Full title: Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Authors: Cleary, Brian Lowman; Lin, Stacie; Jaenisch, Rudolf; Regev, Aviv; Lander, Eric Steven

DOI: https://hdl.handle.net/1721.1/124366

Thesis

Programming and reprogramming cellular identity

Marson, Alexander · 2008

Full title: Programming and reprogramming cellular identity

Authors: Marson, Alexander

DOI: http://hdl.handle.net/1721.1/43223

Thesis

Reprogramming cellular fate using defined factors

Foreman, Ruth K. (Ruth Kjelgaard) · 2009

Full title: Reprogramming cellular fate using defined factors

Authors: Foreman, Ruth K. (Ruth Kjelgaard)

DOI: http://hdl.handle.net/1721.1/46810

Thesis

Induced pluripotency and reprogramming by defined factors

Carey, Bryce W · 2011

Full title: Induced pluripotency and reprogramming by defined factors

Authors: Carey, Bryce W

DOI: http://hdl.handle.net/1721.1/65752

Thesis

Transdifferentiation of fibroblasts to neural stem cells

Cassady, John P · 2014

Full title: Transdifferentiation of fibroblasts to neural stem cells

Authors: Cassady, John P

DOI: http://hdl.handle.net/1721.1/83634

Thesis

Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

Saad, Norazalina · 2016

Full title: Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

Authors: Saad, Norazalina

DOI: https://eprints.nottingham.ac.uk/36226/1/Final%20Thesis%20Norazalina%20Saad.pdf

Thesis

Developing a model system to investigate the epigenetic mechanisms underlying pluripotency in human cells

Matsa, Elena · 2010

Full title: Developing a model system to investigate the epigenetic mechanisms underlying pluripotency in human cells

Authors: Matsa, Elena

DOI: https://eprints.nottingham.ac.uk/14019/1/523599.pdf

Thesis

Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

Leong, Yeh Chwan · 2018

Full title: Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

Authors: Leong, Yeh Chwan

DOI: https://eprints.nottingham.ac.uk/53330/1/PhD%20thesis%20Leong%20Yeh%20Chwan%20.pdf

Thesis

Reprogramming of the mouse Nanog gene in amphibian oocyte extracts

Bereketoğlu, Sidar · 2016

Full title: Reprogramming of the mouse Nanog gene in amphibian oocyte extracts

Authors: Bereketoğlu, Sidar

DOI: https://eprints.nottingham.ac.uk/38790/1/BEREKETOGLU_S_PHDTHESIS.pdf

Thesis

Gene expression network analysis of the routes to pluripotency

Amaral, Fabio M R · 2018

Full title: Gene expression network analysis of the routes to pluripotency

Authors: Amaral, Fabio M R

DOI: https://eprints.nottingham.ac.uk/49714/1/Thesis_2018.pdf

Thesis

Neuronal Reprogramming to Study Human Brain Aging and Disease

Herdy, Joseph · 2023

Full title: Neuronal Reprogramming to Study Human Brain Aging and Disease

Authors: Herdy, Joseph

DOI: https://escholarship.org/uc/item/0g70b3nb

Thesis

Integrative genomic analysis of cell fate conversion

Li, Zhe · 2014

Full title: Integrative genomic analysis of cell fate conversion

Authors: Li, Zhe

DOI: https://escholarship.org/uc/item/8zb078tv

Thesis

Mechanisms of Transdifferentiation and Regeneration

Madhavan, Mayur C. · 2005

Full title: Mechanisms of Transdifferentiation and Regeneration

Authors: Madhavan, Mayur C.

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=miami1133554812

Thesis

Generation of an HVS-based episomally maintained gene delivery system for reprogramming adult somatic cells

Brown, Hannah Frances · 2012

Full title: Generation of an HVS-based episomally maintained gene delivery system for reprogramming adult somatic cells

Authors: Brown, Hannah Frances

DOI: https://etheses.whiterose.ac.uk/id/eprint/4445/1/Corrected%20Thesis.pdf

Thesis

The Genetics and Epigenetics of Induced Pluripotent Stem Cells

Gore, Athurva Jayavant · 2013

Full title: The Genetics and Epigenetics of Induced Pluripotent Stem Cells

Authors: Gore, Athurva Jayavant

DOI: https://escholarship.org/uc/item/45j1149s

Thesis

The Kruppel-like Factors in Aging and Aging Associated Pathology

Hsieh, Paishiun Nelson · 2018

Full title: The Kruppel-like Factors in Aging and Aging Associated Pathology

Authors: Hsieh, Paishiun Nelson

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1522942623451445

Thesis

Studies on the Mechanism behind Retinal Pigment Epithelium (RPE) Reprogramming

Lu, Tianlin · 2019

Full title: Studies on the Mechanism behind Retinal Pigment Epithelium (RPE) Reprogramming

Authors: Lu, Tianlin

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=miami1575301308695243

Thesis

An mRNA-reprogramming method with improved kinetics and efficiency and the successful transdifferentiation of human fibroblasts using modified mRNA

Preskey, David Alexander · 2017

Full title: An mRNA-reprogramming method with improved kinetics and efficiency and the successful transdifferentiation of human fibroblasts using modified mRNA

Authors: Preskey, David Alexander

DOI: https://etheses.whiterose.ac.uk/id/eprint/18242/1/20170705%20Thesis%2035%20DP.pdf

Thesis

From gene therapy to somatic mutagenesis : insights into the common Hutchinson-Gilford progeria syndrome mutation

Daniel Whisenant (18649048) · 2022

Full title: From gene therapy to somatic mutagenesis : insights into the common Hutchinson-Gilford progeria syndrome mutation

Authors: Daniel Whisenant (18649048)

DOI: oai:figshare.com:article/26924155

Thesis

Using Cellular Reprogramming and CRISPR Technologies for the Study of Neurodegeneration and the Development of Cell-Based Therapies

Urrutia Cabrera, Daniel · 2023

Full title: Using Cellular Reprogramming and CRISPR Technologies for the Study of Neurodegeneration and the Development of Cell-Based Therapies

Authors: Urrutia Cabrera, Daniel

DOI: https://hdl.handle.net/11343/336979

Thesis

Reprogramming human keratinocytes: a non-viral, microRNA approach

Lewis, Fiona

Full title: Reprogramming human keratinocytes: a non-viral, microRNA approach

Authors: Lewis, Fiona

DOI: https://livrepository.liverpool.ac.uk/7073/1/LewisFio_July2012_7073.pdf

Thesis

The Role Of Active Dna Demethylation In Mammalian Epigenetic Reprogramming

Caldwell, Blake Alexander · 2023

Full title: The Role Of Active Dna Demethylation In Mammalian Epigenetic Reprogramming

Authors: Caldwell, Blake Alexander

DOI: https://repository.upenn.edu/handle/20.500.14332/31559

Thesis

A Systems Biology Analysis of Cell Cycle Arrest Suggests that Modular Activation of Stress Responses Underlies Heterogeneous Cellular Senescence and Quiescence Phenotypes

Avelar, Roberto · 2023

Full title: A Systems Biology Analysis of Cell Cycle Arrest Suggests that Modular Activation of Stress Responses Underlies Heterogeneous Cellular Senescence and Quiescence Phenotypes

Authors: Avelar, Roberto

DOI: https://livrepository.liverpool.ac.uk/3173246/1/201329530_Jan2023.pdf

Thesis

BEYOND LUCK OF THE DRAW: UNCOVERING CELL-INTRINSIC DETERMINANTS IN REPROGRAMMING SOMATIC CELLS TO PLURIPOTENCY

Jain, Naveen · 2023

Full title: BEYOND LUCK OF THE DRAW: UNCOVERING CELL-INTRINSIC DETERMINANTS IN REPROGRAMMING SOMATIC CELLS TO PLURIPOTENCY

Authors: Jain, Naveen

DOI: https://repository.upenn.edu/handle/20.500.14332/59121

Thesis

Targeted Epigenetic Editing to Increase Adult Pancreatic Β-Cell Proliferation

Bernstein, Diana Lynne · 2023

Full title: Targeted Epigenetic Editing to Increase Adult Pancreatic Β-Cell Proliferation

Authors: Bernstein, Diana Lynne

DOI: https://repository.upenn.edu/handle/20.500.14332/28440

Thesis

EPIGENETIC AND ENVIRONMENTAL DETERMINANTS OF AGING AND LIFESPAN

Bertucci, Emily Marie · 2024

Full title: EPIGENETIC AND ENVIRONMENTAL DETERMINANTS OF AGING AND LIFESPAN

Authors: Bertucci, Emily Marie

DOI: https://openscholar.uga.edu/record/3580/files/2022-11-23_BERTUCCI_DISSERTATION_FINAL.pdf

Thesis

The knockdown of Dnmt1 using small inhibitory RNA:a method to assist in the reprogramming of a donor genome during nuclear transfer

Adams, Allison Marie · 2024

Full title: The knockdown of Dnmt1 using small inhibitory RNA:a method to assist in the reprogramming of a donor genome during nuclear transfer

Authors: Adams, Allison Marie

DOI: https://openscholar.uga.edu/record/20700/files/adams_allison_m_200412_ms.pdf

Thesis

Analysis of the applicability of iPS cell-based approaches to bypass senescence and to re-establish rejuvenation features in human MSCs from aged individuals

Megges, Matthias · 2016

Full title: Analysis of the applicability of iPS cell-based approaches to bypass senescence and to re-establish rejuvenation features in human MSCs from aged individuals

Authors: Megges, Matthias

DOI: https://refubium.fu-berlin.de/handle/fub188/3452

Thesis

Uncovering the bona fide quiescence transcriptome of aged muscle stem cells after systemic rejuvenation

Ngan, Lok Pui · 2022

Full title: Uncovering the bona fide quiescence transcriptome of aged muscle stem cells after systemic rejuvenation

Authors: Ngan, Lok Pui

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-138540

Thesis

Viral and non-viral generation and characterization of induced pluripotent stem cells from human amniotic fluid cells

Drews, Katharina · 2012

Full title: Viral and non-viral generation and characterization of induced pluripotent stem cells from human amniotic fluid cells

Authors: Drews, Katharina

DOI: https://refubium.fu-berlin.de/handle/fub188/7715

Thesis

Molecular mechanisms involved in the induction of pluripotency

Ruiz Acero, Guifré · 2012

Full title: Molecular mechanisms involved in the induction of pluripotency

Authors: Ruiz Acero, Guifré

DOI: https://refubium.fu-berlin.de/handle/fub188/118

Thesis

Efeitos de diferentes tensões de oxigênio na eficiência da reprogramação e manutenção de células-tronco pluripotentes induzidas de equino

Castro, Raquel Vasconcelos Guimarães de [UNESP] · 2020

Full title: Efeitos de diferentes tensões de oxigênio na eficiência da reprogramação e manutenção de células-tronco pluripotentes induzidas de equino

Authors: Castro, Raquel Vasconcelos Guimarães de [UNESP]

DOI: http://hdl.handle.net/11449/193447

Thesis

Statistical Modelling for Cell Reprogramming

Tran, Andy · 2021

Full title: Statistical Modelling for Cell Reprogramming

Authors: Tran, Andy

DOI: https://hdl.handle.net/2123/26580

Thesis

Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming

Villafranca Locher, Maria Cristina · 2018

Full title: Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming

Authors: Villafranca Locher, Maria Cristina

DOI: http://hdl.handle.net/10919/82864

Thesis

Reprogramming of human somatic cells using epigenetic and non-genetic methods

Han, Jinnuo · 2010

Full title: Reprogramming of human somatic cells using epigenetic and non-genetic methods

Authors: Han, Jinnuo

DOI: http://hdl.handle.net/1959.4/45452

Thesis

Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming

Romanazzo, S; https://orcid.org/0000-0002-7074-1248; Lin, K et al. · 2020

Full title: Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming

Authors: Romanazzo, S ; https://orcid.org/0000-0002-7074-1248; Lin, K; Srivastava, P; Kilian, KA ; https://orcid.org/0000-0002-8963-9796

DOI: http://hdl.handle.net/1959.4/unsworks_76936

Thesis

Strategies for gene editing using the crispr system for the generation of genetically engineered livestock

Oliveira, Gabriella Borba de · 2021

Full title: Strategies for gene editing using the crispr system for the generation of genetically engineered livestock

Authors: Oliveira, Gabriella Borba de

DOI: http://hdl.handle.net/10183/233179

Thesis

Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

Jullien, J; Vodnala, M; Pasque, V et al. · 2017

Full title: Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

Authors: Jullien, J; Vodnala, M; Pasque, V; Oikawa, M; Miyamoto, K; Allen, G; David, SA; Brochard, V; Wang, S; Bradshaw, C; Koseki, H; Sartorelli, V; Beaujean, N; Gurdon, J

DOI: https://www.repository.cam.ac.uk/handle/1810/263488

Thesis

In Vitro Models of Cellular Dedifferentiation for Regenerative Medicine

Williams, Kaylyn Renee · 2018

Full title: In Vitro Models of Cellular Dedifferentiation for Regenerative Medicine

Authors: Williams, Kaylyn Renee

DOI: http://hdl.handle.net/10919/83715

Thesis

Reprogramming of somatic cells: a tool for modelling neurodegenerative diseases

Chung, Henry · 2011

Full title: Reprogramming of somatic cells: a tool for modelling neurodegenerative diseases

Authors: Chung, Henry

DOI: http://hdl.handle.net/1959.4/51665

Thesis

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.

Pereira, Allwyn; Diwakar, Jeisimhan; Masserdotti, Giacomo et al. · 2024

Full title: Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.

DOI: https://www.repository.cam.ac.uk/handle/1810/371198

Thesis

Stochastic modelling of epigenetic regulation: analysis of its heterogeneity and its implications in cell plasticity

Folguera Blasco, Núria · 2019

Full title: Stochastic modelling of epigenetic regulation: analysis of its heterogeneity and its implications in cell plasticity

Authors: Folguera Blasco, Núria

DOI: http://hdl.handle.net/10803/666963

Thesis

Induced pluripotent stem cells reprogramming: Epigenetics and applications in the regenerative medicine

Ferreira, Julio Cesar Batista · 2017

Full title: Induced pluripotent stem cells reprogramming: Epigenetics and applications in the regenerative medicine

Authors: Ferreira, Julio Cesar Batista

DOI: https://doi.org/10.1590/1806-9282.63.02.180

Thesis

Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming

Khaw, Swea-Ling; Koh, Cheng-Gee; Lim, Bing et al. · 2015

Full title: Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming

Authors: Khaw, Swea-Ling; Koh, Cheng-Gee; Lim, Bing; Chua, Min-Wen; Ng, Shyh-Chang

DOI: https://hdl.handle.net/10356/103359

Thesis

Partial Reprogramming: A Shortcut to Rejuvenation

Lam, David Du · 2019

Full title: Partial Reprogramming: A Shortcut to Rejuvenation

Authors: Lam, David Du

DOI: https://escholarship.org/uc/item/9cz440mz

Thesis

Prevention of cellular aging in vitro

Kubovčák, Matej · 2023

Full title: Prevention of cellular aging in vitro

Authors: Kubovčák, Matej

DOI: http://hdl.handle.net/20.500.11956/181315

Thesis

Hearts and bones': the ups and downs of plasticity' in stem cell biology

Bonfanti, Paola; Barrandon, Yann; Cossu, Giulio · 2012

Full title: Hearts and bones': the ups and downs of plasticity' in stem cell biology

Authors: Bonfanti, Paola; Barrandon, Yann; Cossu, Giulio

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80760

Thesis

Confounding factors from inducible systems for spatiotemporal gene expression regulation

Wuest, Rob C. I.; Houtkooper, Riekelt H.; Auwerx, Johan · 2020

Full title: Confounding factors from inducible systems for spatiotemporal gene expression regulation

Authors: Wuest, Rob C. I.; Houtkooper, Riekelt H.; Auwerx, Johan

DOI: https://infoscience.epfl.ch/handle/20.500.14299/170461

Thesis

Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Unzu, Carmen; Friedli, Marc; Bosman, Alexis et al. · 2016

Full title: Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

DOI: https://infoscience.epfl.ch/handle/20.500.14299/128018

Thesis

Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

Hung, SSC; Van Bergen, NJ; Jackson, S et al. · 2018

Full title: Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

Authors: Hung, SSC; Van Bergen, NJ; Jackson, S; Liang, H; Mackey, DA; Hernández, D; Lim, SY; Hewitt, AW; Trounce, I; Pébay, A; Wong, RCB

DOI: https://hdl.handle.net/11343/212358

Thesis

Metabolism is a key regulator of induced pluripotent stem cell reprogramming

Spyrou, J; Gardner, DK; Harvey, AJ · 2020

Full title: Metabolism is a key regulator of induced pluripotent stem cell reprogramming

Authors: Spyrou, J; Gardner, DK; Harvey, AJ

DOI: https://hdl.handle.net/11343/245921

Thesis

Potentials of cellular reprogramming as a novel strategy for neuroregeneration

Fang, L; El Wazan, L; Tan, C et al. · 2020

Full title: Potentials of cellular reprogramming as a novel strategy for neuroregeneration

Authors: Fang, L; El Wazan, L; Tan, C; Nguyen, T; Hung, SSC; Hewitt, AW; Wong, RCB

DOI: https://hdl.handle.net/11343/249971

Thesis

Using transcription factors for direct reprogramming of neurons in vitro

El Wazan, L; Urrutia-Cabrera, D; Wong, RCB · 2020

Full title: Using transcription factors for direct reprogramming of neurons in vitro

Authors: El Wazan, L; Urrutia-Cabrera, D; Wong, RCB

DOI: https://hdl.handle.net/11343/246451

Thesis

BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming

Kim, EJY; Anko, ML; Flensberg, C et al. · 2020

Full title: BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming

Authors: Kim, EJY; Anko, ML; Flensberg, C; Majewski, IJ; Geng, FS; Firas, J; Huang, DCS; van Delft, MF; Heath, JK

DOI: https://hdl.handle.net/11343/253104

Thesis

Corrigendum: Potentials of cellular reprogramming as a novel strategy for neuroregeneration (Front. Cell. Neurosci., (2018), 12, 10.3389/fncel.2018.00460)

Fang, L; El Wazan, L; Tan, C et al. · 2020

Full title: Corrigendum: Potentials of cellular reprogramming as a novel strategy for neuroregeneration (Front. Cell. Neurosci., (2018), 12, 10.3389/fncel.2018.00460)

Authors: Fang, L; El Wazan, L; Tan, C; Nguyen, T; Hung, SSC; Hewitt, AW; Wong, RCB

DOI: https://hdl.handle.net/11343/251180

Thesis

Induction of pluripotency in adult equine fibroblasts without c-MYC

Khodadadi, K; Sumer, H; Pashaiasl, M et al. · 2020

Full title: Induction of pluripotency in adult equine fibroblasts without c-MYC

Authors: Khodadadi, K; Sumer, H; Pashaiasl, M; Lim, S; Williamson, M; Verma, PJ

DOI: https://hdl.handle.net/11343/255787

Thesis

Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts

Liu, J; Ashton, MP; Sumer, H et al. · 2020

Full title: Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts

Authors: Liu, J; Ashton, MP; Sumer, H; O'Bryan, MK; Brodnicki, TC; Verma, PJ

DOI: https://hdl.handle.net/11343/257005

Thesis

An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

Lee, DS; Shin, JY; Tonge, PD et al. · 2020

Full title: An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

DOI: https://hdl.handle.net/11343/258237

Thesis

DNA methylation status correlates with adult β-cell regeneration capacity

Khurana, I; Al-Hasani, K; Maxwell, S et al. · 2021

Full title: DNA methylation status correlates with adult β-cell regeneration capacity

Authors: Khurana, I; Al-Hasani, K; Maxwell, S; K.N, H; Okabe, J; Cooper, ME; Collombat, P; El-Osta, A

DOI: https://hdl.handle.net/11343/272983

Thesis

Multi-tissue DNA methylation age predictor in mouse

Stubbs, TM; Bonder, MJ; Stark, A-K et al. · 2021

Full title: Multi-tissue DNA methylation age predictor in mouse

Authors: Stubbs, TM; Bonder, MJ; Stark, A-K; Krueger, F; von Meyenn, F; Stegle, O; Reik, W

DOI: https://hdl.handle.net/11343/273088

Thesis

Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle

Voisin, S; Jacques, M; Landen, S et al. · 2022

Full title: Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle

DOI: https://hdl.handle.net/11343/301767

Thesis

Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

Nefzger, CM; Jardé, T; Srivastava, A et al. · 2022

Full title: Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

DOI: https://hdl.handle.net/11343/316555

Thesis

Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation

Arez, M; Eckersley-Maslin, M; Klobučar, T et al. · 2022

Full title: Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation

Authors: Arez, M; Eckersley-Maslin, M; Klobučar, T; von Gilsa Lopes, J; Krueger, F; Mupo, A; Raposo, AC; Oxley, D; Mancino, S; Gendrel, AV; Bernardes de Jesus, B; da Rocha, ST

DOI: https://hdl.handle.net/11343/318347

Thesis

Microencapsulation-based cell therapies

Marikar, SN; El-Osta, A; Johnston, A et al. · 2022

Full title: Microencapsulation-based cell therapies

Authors: Marikar, SN; El-Osta, A; Johnston, A; Such, G; Al-Hasani, K

DOI: https://hdl.handle.net/11343/316379

Thesis

Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity

Huyghe, A; Furlan, G; Schroeder, J et al. · 2022

Full title: Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity

DOI: https://hdl.handle.net/11343/320010

Thesis

Non-viral direct reprogramming strategies for the creation of insulin producing cells for type 1 diabetes

Risser, Ian · 2020

Full title: Non-viral direct reprogramming strategies for the creation of insulin producing cells for type 1 diabetes

Authors: Risser, Ian

DOI: http://hdl.handle.net/1811/92081

Thesis

Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

Isaksson, Johannes · 2018

Full title: Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

Authors: Isaksson, Johannes

DOI: http://lup.lub.lu.se/student-papers/record/8958666

Thesis

Neuronal Reprogramming via Nanochannel Electroporation

Ortiz Villabona, Cristina · 2015

Full title: Neuronal Reprogramming via Nanochannel Electroporation

Authors: Ortiz Villabona, Cristina

DOI: http://hdl.handle.net/1811/68920

Thesis

Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Yeola, A; Subramanian, S; Oliver, RA et al. · 2022

Full title: Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

DOI: https://hdl.handle.net/11343/304557

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Full title: us-2025263669-a1

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Full title: us-8530238-b2

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Full title: us-8338178-b2

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Full title: us-8772031-b2

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Full title: us-9012219-b2

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Full title: us-8907055-b2

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Full title: us-8900871-b2

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· 2016

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· 2017

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· 2018

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· 2018

Full title: us-9909105-b2

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· 2018

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· 2018

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· 2018

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· 2018

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· 2018

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· 2018

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· 2018

Full title: us-10106772-b2

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· 2019

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· 2018

Full title: us-10155929-b2

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· 2019

Full title: us-10221397-b2

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Full title: us-10131879-b2

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· 2020

Full title: us-10729723-b2

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· 2019

Full title: us-10226486-b2

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· 2019

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· 2019

Full title: us-10227565-b2

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· 2019

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· 2020

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· 2019

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· 2020

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· 2020

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· 2019

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· 2021

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· 2021

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· 2020

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· 2021

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· 2021

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· 2021

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· 2019

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