Evidence For Pd 1 Pd L1 Combination Immunotherapie

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Paper The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials.

Pu, Wenji, Li, Shasha, Zhang, Jinliang, Huang, Jijie, Li, Jishi, Jiang, Yong, Xu, Zhiyuan, Yi, Fan, Lan, Yuling, Xiao, Qin, Chen, Wenqi, Jin, Jing · 2025 · Frontiers in immunology · DOI

Full title: The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials.

Authors: Pu, Wenji, Li, Shasha, Zhang, Jinliang, Huang, Jijie, Li, Jishi, Jiang, Yong, Xu, Zhiyuan, Yi, Fan, Lan, Yuling, Xiao, Qin, Chen, Wenqi, Jin, Jing

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1566939

Paper Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer

Yaqi Zhu · 2023 · Highlights in Science Engineering and Technology · DOI

Full title: Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer

Authors: Yaqi Zhu

Year: 2023

Venue: Highlights in Science Engineering and Technology

DOI: https://doi.org/10.54097/pjjvd009

Paper Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy

Pan, Chong-xian, Liu, Hongtao, Robins, Elizabeth, Song, Wenru, Liu, Delong, Li, Zihai, Zheng, Lei · 2020 · Journal of Hematology & Oncology · DOI

Full title: Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy

Authors: Pan, Chong-xian, Liu, Hongtao, Robins, Elizabeth, Song, Wenru, Liu, Delong, Li, Zihai, Zheng, Lei

Year: 2020

Venue: Journal of Hematology & Oncology

DOI: https://doi.org/10.1186/s13045-020-00862-w

Paper Immune Therapeutics in the Treatment of Advanced Gastric and Esophageal Cancer

R. Park, S. Williamson, A. Kasi, A. Saeed · 2018 · Anticancer Research · DOI

Full title: Immune Therapeutics in the Treatment of Advanced Gastric and Esophageal Cancer

Authors: R. Park, S. Williamson, A. Kasi, A. Saeed

Year: 2018

Venue: Anticancer Research

DOI: https://doi.org/10.21873/anticanres.12891

Paper Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma.

Heinrich, Bernd, Ruf, Benjamin, Subramanyam, Varun, Myojin, Yuta, Lai, Chunwei W, Craig, Amanda J, Fu, Jianyang, Xie, Changqing, Kroemer, Alexander, Greten, Tim F, Korangy, Firouzeh · 2022 · Frontiers in immunology · DOI

Full title: Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma.

Authors: Heinrich, Bernd, Ruf, Benjamin, Subramanyam, Varun, Myojin, Yuta, Lai, Chunwei W, Craig, Amanda J, Fu, Jianyang, Xie, Changqing, Kroemer, Alexander, Greten, Tim F, Korangy, Firouzeh

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.849958

Paper Indicators of responsiveness to immune checkpoint inhibitors.

Shields, Bradley D, Mahmoud, Fade, Taylor, Erin M, Byrum, Stephanie D, Sengupta, Deepanwita, Koss, Brian, Baldini, Giulia, Ransom, Seth, Cline, Kyle, Mackintosh, Samuel G, Edmondson, Ricky D, Shalin, Sara, Tackett, Alan J · 2017 · Scientific reports · DOI

Full title: Indicators of responsiveness to immune checkpoint inhibitors.

Authors: Shields, Bradley D, Mahmoud, Fade, Taylor, Erin M, Byrum, Stephanie D, Sengupta, Deepanwita, Koss, Brian, Baldini, Giulia, Ransom, Seth, Cline, Kyle, Mackintosh, Samuel G, Edmondson, Ricky D, Shalin, Sara, Tackett, Alan J

Year: 2017

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-017-01000-2

Paper To be, or not to be immunocompetent.

Volk, Hans-Dieter, Reinke, Petra · 2013 · Critical care (London, England) · DOI

Full title: To be, or not to be immunocompetent.

Authors: Volk, Hans-Dieter, Reinke, Petra

Year: 2013

Venue: Critical care (London, England)

DOI: https://doi.org/10.1186/cc12897

Paper Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies.

Hernandez, Carlos, Arasanz, Hugo, Chocarro, Luisa, Bocanegra, Ana, Zuazo, Miren, Fernandez-Hinojal, Gonzalo, Blanco, Ester, Vera, Ruth, Escors, David, Kochan, Grazyna · 2020 · International journal of molecular sciences · DOI

Full title: Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies.

Authors: Hernandez, Carlos, Arasanz, Hugo, Chocarro, Luisa, Bocanegra, Ana, Zuazo, Miren, Fernandez-Hinojal, Gonzalo, Blanco, Ester, Vera, Ruth, Escors, David, Kochan, Grazyna

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21072411

Paper The bladder cancer immune micro-environment in the context of response to immune checkpoint inhibition.

van Dorp, Jeroen, van der Heijden, Michiel S · 2023 · Frontiers in immunology · DOI

Full title: The bladder cancer immune micro-environment in the context of response to immune checkpoint inhibition.

Authors: van Dorp, Jeroen, van der Heijden, Michiel S

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1235884

Paper Endometrial Carcinoma: Immune Microenvironment and Emerging Treatments in Immuno-Oncology.

Rousset-Rouviere, Sandrine, Rochigneux, Philippe, Chrétien, Anne-Sophie, Fattori, Stéphane, Gorvel, Laurent, Provansal, Magali, Lambaudie, Eric, Olive, Daniel, Sabatier, Renaud · 2021 · Biomedicines · DOI

Full title: Endometrial Carcinoma: Immune Microenvironment and Emerging Treatments in Immuno-Oncology.

Authors: Rousset-Rouviere, Sandrine, Rochigneux, Philippe, Chrétien, Anne-Sophie, Fattori, Stéphane, Gorvel, Laurent, Provansal, Magali, Lambaudie, Eric, Olive, Daniel, Sabatier, Renaud

Year: 2021

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines9060632

Paper Influence of age on the efficacy of immune checkpoint inhibitors in advanced cancers: a systematic review and meta-analysis.

Ninomiya, Kiichiro, Oze, Isao, Kato, Yuka, Kubo, Toshio, Ichihara, Eiki, Rai, Kammei, Ohashi, Kadoaki, Kozuki, Toshiyuki, Tabata, Masahiro, Maeda, Yoshinobu, Kiura, Katsuyuki, Hotta, Katsuyuki · 2020 · Acta oncologica (Stockholm, Sweden) · DOI

Full title: Influence of age on the efficacy of immune checkpoint inhibitors in advanced cancers: a systematic review and meta-analysis.

Authors: Ninomiya, Kiichiro, Oze, Isao, Kato, Yuka, Kubo, Toshio, Ichihara, Eiki, Rai, Kammei, Ohashi, Kadoaki, Kozuki, Toshiyuki, Tabata, Masahiro, Maeda, Yoshinobu, Kiura, Katsuyuki, Hotta, Katsuyuki

Year: 2020

Venue: Acta oncologica (Stockholm, Sweden)

DOI: https://doi.org/10.1080/0284186X.2019.1695062

Paper Hepatocellular Carcinoma: An Overview of the Changing Landscape of Treatment Options

Koulouris, Andreas, Tsagkaris, Christos, Spyrou, V., Pappa, Eleni V., Troullinou, Aikaterini, Nikolaou, Michail · 2021 · Journal of Hepatocellular Carcinoma · DOI

Full title: Hepatocellular Carcinoma: An Overview of the Changing Landscape of Treatment Options

Authors: Koulouris, Andreas, Tsagkaris, Christos, Spyrou, V., Pappa, Eleni V., Troullinou, Aikaterini, Nikolaou, Michail

Year: 2021

Venue: Journal of Hepatocellular Carcinoma

DOI: https://doi.org/10.2147/jhc.s300182

Paper Emerging immunotherapy and tumor microenvironment for advanced sarcoma: a comprehensive review.

Huang, Hai, Fan, Yiwei, Zhang, Shuling, Bai, Xueli, Wang, Xiaonan, Shan, Fengping · 2025 · Frontiers in immunology · DOI

Full title: Emerging immunotherapy and tumor microenvironment for advanced sarcoma: a comprehensive review.

Authors: Huang, Hai, Fan, Yiwei, Zhang, Shuling, Bai, Xueli, Wang, Xiaonan, Shan, Fengping

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1507870

Paper Pulmonary Toxicities Associated With the Use of Immune Checkpoint Inhibitors: An Update From the Immuno-Oncology Subgroup of the Neutropenia, Infection & Myelosuppression Study Group of the Multinational Association for Supportive Care in Cancer.

Rapoport, Bernardo L, Shannon, Vickie R, Cooksley, Tim, Johnson, Douglas B, Anderson, Lindsay, Blidner, Ada G, Tintinger, Gregory R, Anderson, Ronald · 2021 · Frontiers in pharmacology · DOI

Full title: Pulmonary Toxicities Associated With the Use of Immune Checkpoint Inhibitors: An Update From the Immuno-Oncology Subgroup of the Neutropenia, Infection & Myelosuppression Study Group of the Multinational Association for Supportive Care in Cancer.

Authors: Rapoport, Bernardo L, Shannon, Vickie R, Cooksley, Tim, Johnson, Douglas B, Anderson, Lindsay, Blidner, Ada G, Tintinger, Gregory R, Anderson, Ronald

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.743582

Paper Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Bjoern, Jon, Lyngaa, Rikke, Andersen, Rikke, Hölmich, Lisbet Rosenkrantz, Hadrup, Sine Reker, Donia, Marco, Svane, Inge Marie · 2017 · Oncotarget · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Authors: Bjoern, Jon, Lyngaa, Rikke, Andersen, Rikke, Hölmich, Lisbet Rosenkrantz, Hadrup, Sine Reker, Donia, Marco, Svane, Inge Marie

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.16003

Paper Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients.

Marable, Jonathan, Ruiz, Damien, Jaiswal, Anil K, Bhattacharya, Ritankar, Pantazes, Robert, Agarwal, Payal, Suryawanshi, Amol S, Bedi, Deepa, Mishra, Amarjit, Smith, Bruce F, Sandey, Maninder · 2021 · Scientific reports · DOI

Full title: Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients.

Authors: Marable, Jonathan, Ruiz, Damien, Jaiswal, Anil K, Bhattacharya, Ritankar, Pantazes, Robert, Agarwal, Payal, Suryawanshi, Amol S, Bedi, Deepa, Mishra, Amarjit, Smith, Bruce F, Sandey, Maninder

Year: 2021

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-021-00325-3

Paper Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for internists and general practitioners.

Wojtukiewicz, Marek Z, Rek, Magdalena M, Karpowicz, Kamil, Górska, Maria, Polityńska, Barbara, Wojtukiewicz, Anna M, Moniuszko, Marcin, Radziwon, Piotr, Tucker, Stephanie C, Honn, Kenneth V · 2021 · Cancer metastasis reviews · DOI

Full title: Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for internists and general practitioners.

Authors: Wojtukiewicz, Marek Z, Rek, Magdalena M, Karpowicz, Kamil, Górska, Maria, Polityńska, Barbara, Wojtukiewicz, Anna M, Moniuszko, Marcin, Radziwon, Piotr, Tucker, Stephanie C, Honn, Kenneth V

Year: 2021

Venue: Cancer metastasis reviews

DOI: https://doi.org/10.1007/s10555-021-09976-0

Paper From Bench to Bladder: The Rise in Immune Checkpoint Inhibition in the Treatment of Non-Muscle Invasive Bladder Cancer.

Burns, Caitlin P, Parker, Jacob M, Schaap, Dylan M, Wakefield, Mark R, Fang, Yujiang · 2025 · Cancers · DOI

Full title: From Bench to Bladder: The Rise in Immune Checkpoint Inhibition in the Treatment of Non-Muscle Invasive Bladder Cancer.

Authors: Burns, Caitlin P, Parker, Jacob M, Schaap, Dylan M, Wakefield, Mark R, Fang, Yujiang

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17071135

Paper Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping · 2020 · Frontiers in Immunology · DOI

Full title: Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Authors: Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping

Year: 2020

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2020.01708

Paper Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment

Wang, Jiewen, Kang, Guangbo, Yuan, Haibin, Cao, Xiaocang, Huang, He, Marco, Ario de · 2022 · Frontiers in Immunology · DOI

Full title: Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment

Authors: Wang, Jiewen, Kang, Guangbo, Yuan, Haibin, Cao, Xiaocang, Huang, He, Marco, Ario de

Year: 2022

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2021.838082

Paper An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma

Huang, Yaxuan, Lan, Yunyun, Zhang, Zhe, Xiao, Xue, Huang, Tingting · 2022 · Frontiers in Oncology · DOI

Full title: An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma

Authors: Huang, Yaxuan, Lan, Yunyun, Zhang, Zhe, Xiao, Xue, Huang, Tingting

Year: 2022

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2022.800315

Paper Immunopathogenesis of Immune Checkpoint Inhibitor-Related Adverse Events: Roles of the Intestinal Microbiome and Th17 Cells.

Anderson, Ronald, Theron, Annette J, Rapoport, Bernardo L · 2019 · Frontiers in immunology · DOI

Full title: Immunopathogenesis of Immune Checkpoint Inhibitor-Related Adverse Events: Roles of the Intestinal Microbiome and Th17 Cells.

Authors: Anderson, Ronald, Theron, Annette J, Rapoport, Bernardo L

Year: 2019

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2019.02254

Paper Immunotherapy in Treating EGFR-Mutant Lung Cancer: Current Challenges and New Strategies

To, Kenneth K.W., Fong, Winnie, Cho, William C. · 2021 · Frontiers in Oncology · DOI

Full title: Immunotherapy in Treating EGFR-Mutant Lung Cancer: Current Challenges and New Strategies

Authors: To, Kenneth K.W., Fong, Winnie, Cho, William C.

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.635007

Paper The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

Botticelli, Andrea, Onesti, Concetta Elisa, Zizzari, Ilaria, Cerbelli, Bruna, Sciattella, Paolo, Occhipinti, Mario, Roberto, Michela, Di Pietro, Francesca, Bonifacino, Adriana, Ghidini, Michele, Vici, Patrizia, Pizzuti, Laura, Napoletano, Chiara, Strigari, Lidia, D'Amati, Giulia, Mazzuca, Federica, Nuti, Marianna, Marchetti, Paolo · 2017 · Oncotarget · DOI

Full title: The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

Authors: Botticelli, Andrea, Onesti, Concetta Elisa, Zizzari, Ilaria, Cerbelli, Bruna, Sciattella, Paolo, Occhipinti, Mario, Roberto, Michela, Di Pietro, Francesca, Bonifacino, Adriana, Ghidini, Michele, Vici, Patrizia, Pizzuti, Laura, Napoletano, Chiara, Strigari, Lidia, D'Amati, Giulia, Mazzuca, Federica, Nuti, Marianna, Marchetti, Paolo

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.22242

Paper Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions.

Grubczak, Kamil, Kretowska-Grunwald, Anna, Groth, Dawid, Poplawska, Izabela, Eljaszewicz, Andrzej, Bolkun, Lukasz, Starosz, Aleksandra, Holl, Jordan M, Mysliwiec, Marta, Kruszewska, Joanna, Wojtukiewicz, Marek Z, Moniuszko, Marcin · 2021 · Cells · DOI

Full title: Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions.

Authors: Grubczak, Kamil, Kretowska-Grunwald, Anna, Groth, Dawid, Poplawska, Izabela, Eljaszewicz, Andrzej, Bolkun, Lukasz, Starosz, Aleksandra, Holl, Jordan M, Mysliwiec, Marta, Kruszewska, Joanna, Wojtukiewicz, Marek Z, Moniuszko, Marcin

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10082044

Paper Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.

Majumder, Biswanath, Datta, Santanu · 2025 · Frontiers in immunology · DOI

Full title: Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.

Authors: Majumder, Biswanath, Datta, Santanu

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1676702

Paper Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials.

Grassadonia, Antonino, Sperduti, Isabella, Vici, Patrizia, Iezzi, Laura, Brocco, Davide, Gamucci, Teresa, Pizzuti, Laura, Maugeri-Saccà, Marcello, Marchetti, Paolo, Cognetti, Gaetana, De Tursi, Michele, Natoli, Clara, Barba, Maddalena, Tinari, Nicola · 2018 · Journal of clinical medicine · DOI

Full title: Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials.

Authors: Grassadonia, Antonino, Sperduti, Isabella, Vici, Patrizia, Iezzi, Laura, Brocco, Davide, Gamucci, Teresa, Pizzuti, Laura, Maugeri-Saccà, Marcello, Marchetti, Paolo, Cognetti, Gaetana, De Tursi, Michele, Natoli, Clara, Barba, Maddalena, Tinari, Nicola

Year: 2018

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm7120542

Paper Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas · 2019 · PloS one · DOI

Full title: Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Authors: Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas

Year: 2019

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0219517

Paper The role of BRAF V600 mutation in melanoma

P. Ascierto, J. Kirkwood, J. Grob, E. Simeone, A. Grimaldi, M. Maio, G. Palmieri, A. Testori, F. Marincola, N. Mozzillo · 2012 · Journal of Translational Medicine · DOI

Full title: The role of BRAF V600 mutation in melanoma

Authors: P. Ascierto, J. Kirkwood, J. Grob, E. Simeone, A. Grimaldi, M. Maio, G. Palmieri, A. Testori, F. Marincola, N. Mozzillo

Year: 2012

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/1479-5876-10-85

Paper Immunotherapy in Triple-Negative Breast Cancer: Present and Future

Kim, Isaac, Sanchez, Katherine, McArthur, Heather L., Page, David B. · 2019 · Current Breast Cancer Reports · DOI

Full title: Immunotherapy in Triple-Negative Breast Cancer: Present and Future

Authors: Kim, Isaac, Sanchez, Katherine, McArthur, Heather L., Page, David B.

Year: 2019

Venue: Current Breast Cancer Reports

DOI: https://doi.org/10.1007/s12609-019-00345-z

Paper Front-Line ICI-Based Combination Therapy Post-TKI Resistance May Improve Survival in NSCLC Patients With EGFR Mutation

Tian, Tian, Yu, Min, Li, Juan, Jiang, Mao-Qiong, Ma, Daiyuan, Tang, Shubin, Lin, Zhiyu, Chen, Lin, Gong, Youling, Zhu, Jiang, Zhou, Qiang, Huang, Meijuan, Lü, You · 2021 · Frontiers in Oncology · DOI

Full title: Front-Line ICI-Based Combination Therapy Post-TKI Resistance May Improve Survival in NSCLC Patients With EGFR Mutation

Authors: Tian, Tian, Yu, Min, Li, Juan, Jiang, Mao-Qiong, Ma, Daiyuan, Tang, Shubin, Lin, Zhiyu, Chen, Lin, Gong, Youling, Zhu, Jiang, Zhou, Qiang, Huang, Meijuan, Lü, You

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.739090

Paper Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.

Tulunay Virlan, Aysin, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick, Christodoulou, Maria-Ioanna · 2024 · Frontiers in oncology · DOI

Full title: Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.

Authors: Tulunay Virlan, Aysin, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick, Christodoulou, Maria-Ioanna

Year: 2024

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2024.1476475

Paper OX40 signaling in cancer immunotherapy: mechanisms of action, translational applications, and therapeutic perspectives.

Luo, Yuehua, Li, Jing, Li, Le, Qin, Bingbing, Zhou, Ruisheng, Tang, Ying · 2026 · Frontiers in immunology · DOI

Full title: OX40 signaling in cancer immunotherapy: mechanisms of action, translational applications, and therapeutic perspectives.

Authors: Luo, Yuehua, Li, Jing, Li, Le, Qin, Bingbing, Zhou, Ruisheng, Tang, Ying

Year: 2026

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2026.1724756

Paper Sequential JAK inhibition enhances antitumor immunity after combined anti-PD-1 and anti-CTLA4.

Arias-Badia, Marcel, Chen, PeiXi, Lwin, Yee May, Srinath, Aahir, Lyu, Aram, Fan, Zenghua, Kwek, Serena S, Luong, Diamond N, Setayesh, Ali, Sakamoto, Mason, Clark, Matthew, Lea, Averey, Wolters, Rachel M, Goodearl, Andrew, Harding, Fiona A, Gorman, Jacob V, Ritacco, Wendy, Fong, Lawrence · 2025 · JCI insight · DOI

Full title: Sequential JAK inhibition enhances antitumor immunity after combined anti-PD-1 and anti-CTLA4.

Authors: Arias-Badia, Marcel, Chen, PeiXi, Lwin, Yee May, Srinath, Aahir, Lyu, Aram, Fan, Zenghua, Kwek, Serena S, Luong, Diamond N, Setayesh, Ali, Sakamoto, Mason, Clark, Matthew, Lea, Averey, Wolters, Rachel M, Goodearl, Andrew, Harding, Fiona A, Gorman, Jacob V, Ritacco, Wendy, Fong, Lawrence

Year: 2025

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.187921

Paper IL36 Cooperates With Anti-CTLA-4 mAbs to Facilitate Antitumor Immune Responses

Qu, Qiu‐Xia, Zhai, Zhiwei, Xu, Jieni, Li, Song, Chen, Cheng, Lu, Binfeng · 2020 · Frontiers in Immunology · DOI

Full title: IL36 Cooperates With Anti-CTLA-4 mAbs to Facilitate Antitumor Immune Responses

Authors: Qu, Qiu‐Xia, Zhai, Zhiwei, Xu, Jieni, Li, Song, Chen, Cheng, Lu, Binfeng

Year: 2020

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2020.00634

Paper The impact of immunotherapy on the prognosis of small cell carcinoma of the esophagus: a propensity score-matched analysis of a retrospective study.

Wang, Bing, Liu, Tianxing, Yang, Zhe, Zhu, Hui, Zhou, Fengge, Li, Li, Feng, Bin, Jing, Wang · 2025 · Frontiers in immunology · DOI

Full title: The impact of immunotherapy on the prognosis of small cell carcinoma of the esophagus: a propensity score-matched analysis of a retrospective study.

Authors: Wang, Bing, Liu, Tianxing, Yang, Zhe, Zhu, Hui, Zhou, Fengge, Li, Li, Feng, Bin, Jing, Wang

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1634834

Paper Emerging Immunotherapy Approaches for Advanced Clear Cell Renal Cell Carcinoma.

Meng, Lingbin, Collier, Katharine A, Wang, Peng, Li, Zihai, Monk, Paul, Mortazavi, Amir, Hu, Zhiwei, Spakowicz, Daniel, Zheng, Linghua, Yang, Yuanquan · 2023 · Cells · DOI

Full title: Emerging Immunotherapy Approaches for Advanced Clear Cell Renal Cell Carcinoma.

Authors: Meng, Lingbin, Collier, Katharine A, Wang, Peng, Li, Zihai, Monk, Paul, Mortazavi, Amir, Hu, Zhiwei, Spakowicz, Daniel, Zheng, Linghua, Yang, Yuanquan

Year: 2023

Venue: Cells

DOI: https://doi.org/10.3390/cells13010034

Paper Immune checkpoint inhibitors-associated cranial nerves involvement: a systematic literature review on 136 patients.

Pichon, Samuel, Aigrain, Pauline, Lacombe, Charlotte, Lemarchant, Bruno, Ledoult, Emmanuel, Koether, Vincent, Leurs, Amélie, Zebian, Ghadi, Launay, David, Gachet, Benoit, Levy, Clémentine · 2024 · Journal of neurology · DOI

Full title: Immune checkpoint inhibitors-associated cranial nerves involvement: a systematic literature review on 136 patients.

Authors: Pichon, Samuel, Aigrain, Pauline, Lacombe, Charlotte, Lemarchant, Bruno, Ledoult, Emmanuel, Koether, Vincent, Leurs, Amélie, Zebian, Ghadi, Launay, David, Gachet, Benoit, Levy, Clémentine

Year: 2024

Venue: Journal of neurology

DOI: https://doi.org/10.1007/s00415-024-12660-2

Paper Programmed cell death 1 checkpoint inhibitors in the treatment of patients with advanced melanoma.

Mackiewicz, Jacek, Mackiewicz, Andrzej · 2017 · Contemporary oncology (Poznan, Poland) · DOI

Full title: Programmed cell death 1 checkpoint inhibitors in the treatment of patients with advanced melanoma.

Authors: Mackiewicz, Jacek, Mackiewicz, Andrzej

Year: 2017

Venue: Contemporary oncology (Poznan, Poland)

DOI: https://doi.org/10.5114/wo.2017.66651

Paper m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma.

Huang, Xiongpei, Qiu, Zecheng, Li, Liusheng, Chen, Bin, Huang, Peiyuan · 2021 · Aging · DOI

Full title: m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma.

Authors: Huang, Xiongpei, Qiu, Zecheng, Li, Liusheng, Chen, Bin, Huang, Peiyuan

Year: 2021

Venue: Aging

DOI: https://doi.org/10.18632/aging.203456

Paper Checkpoint inhibition in hematologic malignancies.

Tsumura, Aaron, Levis, Daniel, Tuscano, Joseph M · 2023 · Frontiers in oncology · DOI

Full title: Checkpoint inhibition in hematologic malignancies.

Authors: Tsumura, Aaron, Levis, Daniel, Tuscano, Joseph M

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1288172

Paper [Dendritic cell and cancer immune checkpoint].

Kubo, Terufumi, Hirohashi, Yoshihiko, Torigoe, Toshihiko · 2016 · Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology · DOI

Full title: [Dendritic cell and cancer immune checkpoint].

Authors: Kubo, Terufumi, Hirohashi, Yoshihiko, Torigoe, Toshihiko

Year: 2016

Venue: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

DOI: https://doi.org/10.2177/jsci.39.468

Paper Current Advances in Checkpoint Inhibitors: Lessons from Non-Central Nervous System Cancers and Potential for Glioblastoma.

Lakin, Natasha, Rulach, Robert, Nowicki, Stefan, Kurian, Kathreena M · 2017 · Frontiers in oncology · DOI

Full title: Current Advances in Checkpoint Inhibitors: Lessons from Non-Central Nervous System Cancers and Potential for Glioblastoma.

Authors: Lakin, Natasha, Rulach, Robert, Nowicki, Stefan, Kurian, Kathreena M

Year: 2017

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2017.00141

Paper Successful Treatment of Sarcomatoid Carcinoma Using Nivolumab Plus Ipilimumab Combination Immunotherapy: a Case Report

Watanabe, Hiroki, Murai, Yui, Suzuki, Asumi, Yamagishi, Ikumi, Ogata, Eiji, Miyabayashi, Takao, Youkou, Akira, Watanabe, Masatoshi, Abe, Tetsuya · 2022 · Haigan · DOI

Full title: Successful Treatment of Sarcomatoid Carcinoma Using Nivolumab Plus Ipilimumab Combination Immunotherapy: a Case Report

Authors: Watanabe, Hiroki, Murai, Yui, Suzuki, Asumi, Yamagishi, Ikumi, Ogata, Eiji, Miyabayashi, Takao, Youkou, Akira, Watanabe, Masatoshi, Abe, Tetsuya

Year: 2022

Venue: Haigan

DOI: https://doi.org/10.2482/haigan.62.996

Paper Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival.

Kamai, Takao, Kijima, Toshiki, Tsuzuki, Toyonori, Nukui, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro · 2021 · Cancer immunology, immunotherapy : CII · DOI

Full title: Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival.

Authors: Kamai, Takao, Kijima, Toshiki, Tsuzuki, Toyonori, Nukui, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro

Year: 2021

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02843-x

Paper An update on the clinical trial research of immunotherapy for glioblastoma.

Zhou, Yichen, Shi, Fanxing, Zhu, Junyu, Yuan, Yi · 2025 · Frontiers in immunology · DOI

Full title: An update on the clinical trial research of immunotherapy for glioblastoma.

Authors: Zhou, Yichen, Shi, Fanxing, Zhu, Junyu, Yuan, Yi

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1582296

Paper Crosstalk of disulfidptosis-related subtypes identifying a prognostic signature to improve prognosis and immunotherapy responses of clear cell renal cell carcinoma patients

Lei Ren, Jinwen Liu, Qingyuan Lin, Tianyi He, Guankai Huang, Weifeng Wang, Xunhao Zhan, Yu He, Bin Huang, Xiaopeng Mao · 2024 · BMC Genomics · DOI

Full title: Crosstalk of disulfidptosis-related subtypes identifying a prognostic signature to improve prognosis and immunotherapy responses of clear cell renal cell carcinoma patients

Authors: Lei Ren, Jinwen Liu, Qingyuan Lin, Tianyi He, Guankai Huang, Weifeng Wang, Xunhao Zhan, Yu He, Bin Huang, Xiaopeng Mao

Year: 2024

Venue: BMC Genomics

DOI: https://doi.org/10.1186/s12864-024-10307-0

Paper The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.

Maurer, Mark F, Lewis, Katherine E, Kuijper, Joseph L, Ardourel, Dan, Gudgeon, Chelsea J, Chandrasekaran, Siddarth, Mudri, Sherri L, Kleist, Kayla N, Navas, Chris, Wolfson, Martin F, Rixon, Mark W, Swanson, Ryan, Dillon, Stacey R, Levin, Steven D, Kimbung, Yengo Raymond, Akutsu, Masato, Logan, Derek T, Walse, Björn, Swiderek, Kristine M, Peng, Stanford L · 2022 · Nature communications · DOI

Full title: The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.

Authors: Maurer, Mark F, Lewis, Katherine E, Kuijper, Joseph L, Ardourel, Dan, Gudgeon, Chelsea J, Chandrasekaran, Siddarth, Mudri, Sherri L, Kleist, Kayla N, Navas, Chris, Wolfson, Martin F, Rixon, Mark W, Swanson, Ryan, Dillon, Stacey R, Levin, Steven D, Kimbung, Yengo Raymond, Akutsu, Masato, Logan, Derek T, Walse, Björn, Swiderek, Kristine M, Peng, Stanford L

Year: 2022

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-022-29286-5

Paper Expression Pattern and Prognostic Value of CTLA-4, CD86, and Tumor-Infiltrating Lymphocytes in Rectal Cancer after Neoadjuvant Chemo(radio)therapy.

Yin, Xin-Ke, Wang, Chao, Feng, Li-Li, Bai, Shao-Mei, Feng, Wei-Xing, Ouyang, Neng-Tai, Chu, Zhong-Hua, Fan, Xin-Juan, Qin, Qi-Yuan · 2022 · Cancers · DOI

Full title: Expression Pattern and Prognostic Value of CTLA-4, CD86, and Tumor-Infiltrating Lymphocytes in Rectal Cancer after Neoadjuvant Chemo(radio)therapy.

Authors: Yin, Xin-Ke, Wang, Chao, Feng, Li-Li, Bai, Shao-Mei, Feng, Wei-Xing, Ouyang, Neng-Tai, Chu, Zhong-Hua, Fan, Xin-Juan, Qin, Qi-Yuan

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14225573

Paper Determinants of Response to Immune Checkpoint Blockade in Pleural Mesothelioma: Molecular, Immunological, and Clinical Perspectives.

Delsignore, Martina, Cassinari, Gaia, Revello, Simona, Cerbone, Luigi, Grosso, Federica, Arsura, Marcello, Porta, Chiara · 2025 · Cancers · DOI

Full title: Determinants of Response to Immune Checkpoint Blockade in Pleural Mesothelioma: Molecular, Immunological, and Clinical Perspectives.

Authors: Delsignore, Martina, Cassinari, Gaia, Revello, Simona, Cerbone, Luigi, Grosso, Federica, Arsura, Marcello, Porta, Chiara

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17244020

Paper Enhancement of antitumor immunity by combining anti-cytotoxic T lymphocyte antigen-4 antibodies and cryotreated tumor lysate-pulsed dendritic cells in murine osteosarcoma.

Kawano, Masanori, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi · 2013 · Oncology reports · DOI

Full title: Enhancement of antitumor immunity by combining anti-cytotoxic T lymphocyte antigen-4 antibodies and cryotreated tumor lysate-pulsed dendritic cells in murine osteosarcoma.

Authors: Kawano, Masanori, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi

Year: 2013

Venue: Oncology reports

DOI: https://doi.org/10.3892/or.2013.2224

Paper Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge.

Hirao, Lauren A, Hokey, David A, Morrow, Matthew P, Jure-Kunkel, Maria N, Weiner, David B · 2011 · PloS one · DOI

Full title: Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge.

Authors: Hirao, Lauren A, Hokey, David A, Morrow, Matthew P, Jure-Kunkel, Maria N, Weiner, David B

Year: 2011

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0024250

Paper Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors.

Gowen, Michael F, Giles, Keith M, Simpson, Danny, Tchack, Jeremy, Zhou, Hua, Moran, Una, Dawood, Zarmeena, Pavlick, Anna C, Hu, Shaohui, Wilson, Melissa A, Zhong, Hua, Krogsgaard, Michelle, Kirchhoff, Tomas, Osman, Iman · 2018 · Journal of translational medicine · DOI

Full title: Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors.

Authors: Gowen, Michael F, Giles, Keith M, Simpson, Danny, Tchack, Jeremy, Zhou, Hua, Moran, Una, Dawood, Zarmeena, Pavlick, Anna C, Hu, Shaohui, Wilson, Melissa A, Zhong, Hua, Krogsgaard, Michelle, Kirchhoff, Tomas, Osman, Iman

Year: 2018

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-018-1452-4

Paper SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors.

Leshem, Yasmin, King, Emily M, Mazor, Ronit, Reiter, Yoram, Pastan, Ira · 2018 · Toxins · DOI

Full title: SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors.

Authors: Leshem, Yasmin, King, Emily M, Mazor, Ronit, Reiter, Yoram, Pastan, Ira

Year: 2018

Venue: Toxins

DOI: https://doi.org/10.3390/toxins10110470

Paper CTLA-4 immunotherapy exposes differences in immune response along with different tumor progression in colorectal cancer.

Fu, Xiaocong, Luo, Hua, Zheng, Yuhui, Wang, Shengpeng, Zhong, Zhangfeng, Wang, Yitao, Yang, Yeguo · 2020 · Aging · DOI

Full title: CTLA-4 immunotherapy exposes differences in immune response along with different tumor progression in colorectal cancer.

Authors: Fu, Xiaocong, Luo, Hua, Zheng, Yuhui, Wang, Shengpeng, Zhong, Zhangfeng, Wang, Yitao, Yang, Yeguo

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.103765

Paper Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular Carcinoma

Alrumaihi, Faris, Alromaihi, Reem A., Kumar, Vikalp, Anwar, Shehwaz · 2025 · Current Issues in Molecular Biology · DOI

Full title: Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular Carcinoma

Authors: Alrumaihi, Faris, Alromaihi, Reem A., Kumar, Vikalp, Anwar, Shehwaz

Year: 2025

Venue: Current Issues in Molecular Biology

DOI: https://doi.org/10.3390/cimb47121056

Paper The Immune Landscape and Immunotherapeutic Strategies in Platinum-Refractory Testicular Germ Cell Tumors.

Evmorfopoulos, Konstantinos, Marsitopoulos, Konstantinos, Karachalios, Raphael, Karathanasis, Athanasios, Dimitropoulos, Konstantinos, Tzortzis, Vassilios, Zachos, Ioannis, Vlachostergios, Panagiotis J · 2024 · Cancers · DOI

Full title: The Immune Landscape and Immunotherapeutic Strategies in Platinum-Refractory Testicular Germ Cell Tumors.

Authors: Evmorfopoulos, Konstantinos, Marsitopoulos, Konstantinos, Karachalios, Raphael, Karathanasis, Athanasios, Dimitropoulos, Konstantinos, Tzortzis, Vassilios, Zachos, Ioannis, Vlachostergios, Panagiotis J

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16020428

Paper Oncolytic peptide LTX-315 plus an anti-CTLA-4 antibody induces a synergistic anti-cancer immune response in residual tumors after radiofrequency ablation of hepatocellular carcinoma.

Sun, Bo, Liu, Jiayun, Liu, Xiaocui, Li, Jing, Zhang, Guilin, Sun, Tao, Zheng, Chuansheng, Kan, Xuefeng · 2025 · Cell death & disease · DOI

Full title: Oncolytic peptide LTX-315 plus an anti-CTLA-4 antibody induces a synergistic anti-cancer immune response in residual tumors after radiofrequency ablation of hepatocellular carcinoma.

Authors: Sun, Bo, Liu, Jiayun, Liu, Xiaocui, Li, Jing, Zhang, Guilin, Sun, Tao, Zheng, Chuansheng, Kan, Xuefeng

Year: 2025

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-025-07622-z

Paper The Growing Skyline of Advanced Hepatocellular Carcinoma Treatment: A Review

Schipilliti, Francesca Matilde, Garajová, Ingrid, Rovesti, Giulia, Balsano, Rita, Piacentini, Federico, Dominici, Massimo, Gelsomino, Fabio · 2021 · Pharmaceuticals · DOI

Full title: The Growing Skyline of Advanced Hepatocellular Carcinoma Treatment: A Review

Authors: Schipilliti, Francesca Matilde, Garajová, Ingrid, Rovesti, Giulia, Balsano, Rita, Piacentini, Federico, Dominici, Massimo, Gelsomino, Fabio

Year: 2021

Venue: Pharmaceuticals

DOI: https://doi.org/10.3390/ph14010043

Paper Nivolumab plus ipilimumab in the treatment of advanced melanoma.

Tsai, Katy K, Daud, Adil I · 2015 · Journal of hematology & oncology · DOI

Full title: Nivolumab plus ipilimumab in the treatment of advanced melanoma.

Authors: Tsai, Katy K, Daud, Adil I

Year: 2015

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-015-0219-0

Paper A Gene Panel for Early Identification of Future Responders to Immune Checkpoint Blockade.

Panda, Anshuman, Betigeri, Anil, Ganesan, Shridar · 2022 · Frontiers in genetics · DOI

Full title: A Gene Panel for Early Identification of Future Responders to Immune Checkpoint Blockade.

Authors: Panda, Anshuman, Betigeri, Anil, Ganesan, Shridar

Year: 2022

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2022.706468

Paper Immunotherapy: combine and conquer

· 2015 · Nature Medicine · DOI

Full title: Immunotherapy: combine and conquer

Year: 2015

Venue: Nature Medicine

DOI: https://doi.org/10.1038/nm.3865

Paper Risk and incidence of fatal adverse events associated with immune checkpoint inhibitors: a systematic review and meta-analysis.

Jiang, Yi, Zhang, Ning, Pang, Hailin, Gao, Xiaobo, Zhang, Helong · 2019 · Therapeutics and clinical risk management · DOI

Full title: Risk and incidence of fatal adverse events associated with immune checkpoint inhibitors: a systematic review and meta-analysis.

Authors: Jiang, Yi, Zhang, Ning, Pang, Hailin, Gao, Xiaobo, Zhang, Helong

Year: 2019

Venue: Therapeutics and clinical risk management

DOI: https://doi.org/10.2147/TCRM.S191022

Paper Diagnosing and Managing Uveitis Associated with Immune Checkpoint Inhibitors: A Review.

Zhang, Huixin, Houadj, Lysa, Wu, Kevin Y, Tran, Simon D · 2024 · Diagnostics (Basel, Switzerland) · DOI

Full title: Diagnosing and Managing Uveitis Associated with Immune Checkpoint Inhibitors: A Review.

Authors: Zhang, Huixin, Houadj, Lysa, Wu, Kevin Y, Tran, Simon D

Year: 2024

Venue: Diagnostics (Basel, Switzerland)

DOI: https://doi.org/10.3390/diagnostics14030336

Paper Combination Immunotherapy in Prostate Cancer.

Baxevanis, Constantin N, Goulielmaki, Maria, Gritzapis, Angelos D, Fortis, Sotirios P · 2022 · Cancers · DOI

Full title: Combination Immunotherapy in Prostate Cancer.

Authors: Baxevanis, Constantin N, Goulielmaki, Maria, Gritzapis, Angelos D, Fortis, Sotirios P

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14246040

Paper Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis.

Amosu, Mayowa M, Jankowski, Ashleigh M, McCright, Jacob C, Yang, Bennett E, de Oro Fernandez, Juan Grano, Moore, Kaitlyn A, Gadde, Havish S, Donthi, Mehul, Kaluzienski, Michele L, Sriram, Vedanth, Maisel, Katharina · 2024 · bioRxiv : the preprint server for biology · DOI

Full title: Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis.

Authors: Amosu, Mayowa M, Jankowski, Ashleigh M, McCright, Jacob C, Yang, Bennett E, de Oro Fernandez, Juan Grano, Moore, Kaitlyn A, Gadde, Havish S, Donthi, Mehul, Kaluzienski, Michele L, Sriram, Vedanth, Maisel, Katharina

Year: 2024

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.02.06.527331

Paper Efficacy and safety of anti-PD-1/PD-L1 therapy in the treatment of advanced colorectal cancer: a meta-analysis

Yuegang Li, Yuwei Du, Chi Xue, P. Wu, N. Du, Guolian Zhu, Huimian Xu, Zhi Zhu · 2022 · BMC Gastroenterology · DOI

Full title: Efficacy and safety of anti-PD-1/PD-L1 therapy in the treatment of advanced colorectal cancer: a meta-analysis

Authors: Yuegang Li, Yuwei Du, Chi Xue, P. Wu, N. Du, Guolian Zhu, Huimian Xu, Zhi Zhu

Year: 2022

Venue: BMC Gastroenterology

DOI: https://doi.org/10.1186/s12876-022-02511-7

Paper Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils

Xiaochen Wang, M. Cheng, Shuang Chen, Caihua Zhang, Rongsong Ling, Shuqing Qiu, Ke Chen, Bin Zhou, Qiuli Li, W. Lei, Demeng Chen · 2025 · Nature Communications · DOI

Full title: Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils

Authors: Xiaochen Wang, M. Cheng, Shuang Chen, Caihua Zhang, Rongsong Ling, Shuqing Qiu, Ke Chen, Bin Zhou, Qiuli Li, W. Lei, Demeng Chen

Year: 2025

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-025-59050-4

Paper The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead.

Hosseinkhani, Negar, Derakhshani, Afshin, Shadbad, Mahdi Abdoli, Argentiero, Antonella, Racanelli, Vito, Kazemi, Tohid, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad · 2021 · Frontiers in immunology · DOI

Full title: The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead.

Authors: Hosseinkhani, Negar, Derakhshani, Afshin, Shadbad, Mahdi Abdoli, Argentiero, Antonella, Racanelli, Vito, Kazemi, Tohid, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.676181

Paper Various Uses of PD1/PD-L1 Inhibitor in Oncology: Opportunities and Challenges.

Li, Zhitao, Sun, Guoqiang, Sun, Guangshun, Cheng, Ye, Wu, Liangliang, Wang, Qian, Lv, Chengyu, Zhou, Yichan, Xia, Yongxiang, Tang, Weiwei · 2021 · Frontiers in oncology · DOI

Full title: Various Uses of PD1/PD-L1 Inhibitor in Oncology: Opportunities and Challenges.

Authors: Li, Zhitao, Sun, Guoqiang, Sun, Guangshun, Cheng, Ye, Wu, Liangliang, Wang, Qian, Lv, Chengyu, Zhou, Yichan, Xia, Yongxiang, Tang, Weiwei

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.771335

Paper Photodynamic Therapy Using RGD-Functionalized Quantum Dots Elicit a Potent Immune Response in a Syngeneic Mouse Model of Pancreatic Cancer.

Li, Ming-Ming, Zhang, Yi, Sun, Fang, Huai, Man-Xiu, Zhang, Fei-Yu, Pan, Jia-Xing, Qu, Chun-Ying, Shen, Feng, Li, Zheng-Hong, Xu, Lei-Ming · 2024 · International journal of nanomedicine · DOI

Full title: Photodynamic Therapy Using RGD-Functionalized Quantum Dots Elicit a Potent Immune Response in a Syngeneic Mouse Model of Pancreatic Cancer.

Authors: Li, Ming-Ming, Zhang, Yi, Sun, Fang, Huai, Man-Xiu, Zhang, Fei-Yu, Pan, Jia-Xing, Qu, Chun-Ying, Shen, Feng, Li, Zheng-Hong, Xu, Lei-Ming

Year: 2024

Venue: International journal of nanomedicine

DOI: https://doi.org/10.2147/IJN.S479123

Paper Efficacy and safety of combination immunotherapy for treating advanced non-clear cell renal cell carcinoma: A multicenter retrospective study in Japan.

Iinuma, Koji, Sano, Yuta, Nishikawa, Kohei, Taniguchi, Tomoki, Matsuyama, Aika, Ozawa, Kaori, Ishida, Takashi, Tochigi, Kosuke, Tamura, Masataka, Kubota, Yasuaki, Akamatsu, Shusuke, Inoue, Takahiro, Koie, Takuya · 2025 · Scientific reports · DOI

Full title: Efficacy and safety of combination immunotherapy for treating advanced non-clear cell renal cell carcinoma: A multicenter retrospective study in Japan.

Authors: Iinuma, Koji, Sano, Yuta, Nishikawa, Kohei, Taniguchi, Tomoki, Matsuyama, Aika, Ozawa, Kaori, Ishida, Takashi, Tochigi, Kosuke, Tamura, Masataka, Kubota, Yasuaki, Akamatsu, Shusuke, Inoue, Takahiro, Koie, Takuya

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-19523-4

Paper Spatial transcriptomics reveals tumor microenvironment heterogeneity in EBV positive diffuse large B cell lymphoma

Mei He, Meng Liu, Jiayin Yuan, Jin Lv, Wei Li, Qi Yan, Yujiao Tang, Luying Wang, L. Guo, Fang Liu · 2025 · Scientific Reports · DOI

Full title: Spatial transcriptomics reveals tumor microenvironment heterogeneity in EBV positive diffuse large B cell lymphoma

Authors: Mei He, Meng Liu, Jiayin Yuan, Jin Lv, Wei Li, Qi Yan, Yujiao Tang, Luying Wang, L. Guo, Fang Liu

Year: 2025

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-025-00410-x

Paper Early B cell changes predict autoimmunity following combination immune checkpoint blockade.

Das, Rituparna, Bar, Noffar, Ferreira, Michelle, Newman, Aaron M, Zhang, Lin, Bailur, Jithendra Kini, Bacchiocchi, Antonella, Kluger, Harriet, Wei, Wei, Halaban, Ruth, Sznol, Mario, Dhodapkar, Madhav V, Dhodapkar, Kavita M · 2018 · The Journal of clinical investigation · DOI

Full title: Early B cell changes predict autoimmunity following combination immune checkpoint blockade.

Authors: Das, Rituparna, Bar, Noffar, Ferreira, Michelle, Newman, Aaron M, Zhang, Lin, Bailur, Jithendra Kini, Bacchiocchi, Antonella, Kluger, Harriet, Wei, Wei, Halaban, Ruth, Sznol, Mario, Dhodapkar, Madhav V, Dhodapkar, Kavita M

Year: 2018

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI96798

Paper Maximizing Immunotherapy in Sarcoma Using Histology, Biomarkers and Novel Approaches

Stein, Jacob, D’Angelo, Sandra P. · 2022 · touchREVIEWS in Oncology & Haematology · DOI

Full title: Maximizing Immunotherapy in Sarcoma Using Histology, Biomarkers and Novel Approaches

Authors: Stein, Jacob, D’Angelo, Sandra P.

Year: 2022

Venue: touchREVIEWS in Oncology & Haematology

DOI: https://doi.org/10.17925/ohr.2022.18.1.73

Paper Lung cancer immunotherapy: progress, pitfalls, and promises

Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K. · 2023 · Molecular Cancer · DOI

Full title: Lung cancer immunotherapy: progress, pitfalls, and promises

Authors: Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K.

Year: 2023

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-023-01740-y

Paper Clinical Outcomes in Fibrolamellar Hepatocellular Carcinoma Treated with Immune Checkpoint Inhibitors

Krista Y Chen, A. Popovic, D. Hsiehchen, M. Baretti, Paige Griffith, R. Bista, Azarakhsh Baghdadi, I. Kamel, S. Simon, Rachael D. Migler, M. Yarchoan · 2022 · Cancers · DOI

Full title: Clinical Outcomes in Fibrolamellar Hepatocellular Carcinoma Treated with Immune Checkpoint Inhibitors

Authors: Krista Y Chen, A. Popovic, D. Hsiehchen, M. Baretti, Paige Griffith, R. Bista, Azarakhsh Baghdadi, I. Kamel, S. Simon, Rachael D. Migler, M. Yarchoan

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14215347

Paper Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.

Li, Xiaolei, Shao, Changshun, Shi, Yufang, Han, Weidong · 2018 · Journal of hematology & oncology · DOI

Full title: Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.

Authors: Li, Xiaolei, Shao, Changshun, Shi, Yufang, Han, Weidong

Year: 2018

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-018-0578-4

Paper Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression.

Dolina, Joseph S, Lee, Joey, Brightman, Spencer E, McArdle, Sara, Hall, Samantha M, Thota, Rukman R, Lanka, Manasa, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason A, Cohen, Ezra E W, Peters, Bjoern, Schoenberger, Stephen P · 2023 · bioRxiv : the preprint server for biology · DOI

Full title: Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression.

Authors: Dolina, Joseph S, Lee, Joey, Brightman, Spencer E, McArdle, Sara, Hall, Samantha M, Thota, Rukman R, Lanka, Manasa, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason A, Cohen, Ezra E W, Peters, Bjoern, Schoenberger, Stephen P

Year: 2023

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.05.06.539290

Paper Tumor-infiltrating immune cell profiles and changes associate with additional trastuzumab in preoperative chemotherapy for patients with HER2-positive gastric cancer

Cong Chen, Jing Han, Qifei He, Qian Yao, Xueying Wang, Zuofu Peng, Yu Sun, Jiafu Ji, Xiaofang Xing · 2024 · British Journal of Cancer · DOI

Full title: Tumor-infiltrating immune cell profiles and changes associate with additional trastuzumab in preoperative chemotherapy for patients with HER2-positive gastric cancer

Authors: Cong Chen, Jing Han, Qifei He, Qian Yao, Xueying Wang, Zuofu Peng, Yu Sun, Jiafu Ji, Xiaofang Xing

Year: 2024

Venue: British Journal of Cancer

DOI: https://doi.org/10.1038/s41416-024-02835-z

Paper PD‑1/PD‑L1 blockade, a novel strategy for targeting metastatic colorectal cancer: A systematic review and meta‑analysis of randomized trials

Rotundo, Maria, Bagnardi, Vincenzo, Rotundo, Miryam, Comandè, Mario, Zampino, Maria Giulia · 2022 · Oncology Letters · DOI

Full title: PD‑1/PD‑L1 blockade, a novel strategy for targeting metastatic colorectal cancer: A systematic review and meta‑analysis of randomized trials

Authors: Rotundo, Maria, Bagnardi, Vincenzo, Rotundo, Miryam, Comandè, Mario, Zampino, Maria Giulia

Year: 2022

Venue: Oncology Letters

DOI: https://doi.org/10.3892/ol.2022.13254

Paper The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy.

Russell, Bonnie L, Sooklal, Selisha A, Malindisa, Sibusiso T, Daka, Lembelani Jonathan, Ntwasa, Monde · 2021 · Frontiers in oncology · DOI

Full title: The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy.

Authors: Russell, Bonnie L, Sooklal, Selisha A, Malindisa, Sibusiso T, Daka, Lembelani Jonathan, Ntwasa, Monde

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.641428

Paper Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma.

Takahashi, Yutaka, Yasui, Tomohiro, Tamari, Keisuke, Minami, Kazumasa, Otani, Keisuke, Isohashi, Fumiaki, Seo, Yuji, Kambe, Ryosuke, Koizumi, Masahiko, Ogawa, Kazuhiko · 2017 · PloS one · DOI

Full title: Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma.

Authors: Takahashi, Yutaka, Yasui, Tomohiro, Tamari, Keisuke, Minami, Kazumasa, Otani, Keisuke, Isohashi, Fumiaki, Seo, Yuji, Kambe, Ryosuke, Koizumi, Masahiko, Ogawa, Kazuhiko

Year: 2017

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0189697

Paper Complete Remission of Vocal Cord Cancer Treated With Low-Dose Ipilimumab Plus Nivolumab Combined With Interleukin-2 and Hyperthermia.

Kleef, Ralf, Bacher, Viktor, Nagy, Robert, Reisegger, Peter, Bakacs, Tibor · 2021 · Cureus · DOI

Full title: Complete Remission of Vocal Cord Cancer Treated With Low-Dose Ipilimumab Plus Nivolumab Combined With Interleukin-2 and Hyperthermia.

Authors: Kleef, Ralf, Bacher, Viktor, Nagy, Robert, Reisegger, Peter, Bakacs, Tibor

Year: 2021

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.14500

Paper Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis.

Yang, Yana, Li, Linman, Tian, Jing, Ma, Linwen, Wu, Yaoxin, Luo, Qian, Luo, Yan · 2024 · Frontiers in pharmacology · DOI

Full title: Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis.

Authors: Yang, Yana, Li, Linman, Tian, Jing, Ma, Linwen, Wu, Yaoxin, Luo, Qian, Luo, Yan

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1453429

Paper Releasing the brakes: the role of immune checkpoint inhibitors in laryngeal cancer.

Athanasopoulos, Michail, Samara, Pinelopi, Agrogiannis, Georgios, Athanasopoulos, Ioannis, Kavantzas, Nikolaos, Kyrodimos, Efthymios, Mastronikolis, Nicholas S · 2025 · Exploration of targeted anti-tumor therapy · DOI

Full title: Releasing the brakes: the role of immune checkpoint inhibitors in laryngeal cancer.

Authors: Athanasopoulos, Michail, Samara, Pinelopi, Agrogiannis, Georgios, Athanasopoulos, Ioannis, Kavantzas, Nikolaos, Kyrodimos, Efthymios, Mastronikolis, Nicholas S

Year: 2025

Venue: Exploration of targeted anti-tumor therapy

DOI: https://doi.org/10.37349/etat.2025.1002292

Paper PD-1/PD-L1 Inhibitors in Cervical Cancer.

Liu, Yuncong, Wu, Li, Tong, Ruizhan, Yang, Feiyue, Yin, Limei, Li, Mengqian, You, Liting, Xue, Jianxin, Lu, You · 2019 · Frontiers in pharmacology · DOI

Full title: PD-1/PD-L1 Inhibitors in Cervical Cancer.

Authors: Liu, Yuncong, Wu, Li, Tong, Ruizhan, Yang, Feiyue, Yin, Limei, Li, Mengqian, You, Liting, Xue, Jianxin, Lu, You

Year: 2019

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2019.00065

Paper Immunomodulatory Precision: A Narrative Review Exploring the Critical Role of Immune Checkpoint Inhibitors in Cancer Treatment.

Qiu, Junyu, Cheng, Zilin, Jiang, Zheng, Gan, Luhan, Zhang, Zixuan, Xie, Zhenzhen · 2024 · International journal of molecular sciences · DOI

Full title: Immunomodulatory Precision: A Narrative Review Exploring the Critical Role of Immune Checkpoint Inhibitors in Cancer Treatment.

Authors: Qiu, Junyu, Cheng, Zilin, Jiang, Zheng, Gan, Luhan, Zhang, Zixuan, Xie, Zhenzhen

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms25105490

Paper The comparison of efficacy and safety between cadonilimab (PD-1/CTLA-4) and anti-PD-1 inhibitors in patients with recurrent or metastatic cervical cancer: a retrospective real-world study.

Pan, Baoyue, Huang, He, Wan, Ting, Huang, Qidan, He, Shanyang, Xu, Shijie, Chen, Siyu, Yin, Jiaxin, Li, Jundong, Zheng, Min · 2025 · Frontiers in immunology · DOI

Full title: The comparison of efficacy and safety between cadonilimab (PD-1/CTLA-4) and anti-PD-1 inhibitors in patients with recurrent or metastatic cervical cancer: a retrospective real-world study.

Authors: Pan, Baoyue, Huang, He, Wan, Ting, Huang, Qidan, He, Shanyang, Xu, Shijie, Chen, Siyu, Yin, Jiaxin, Li, Jundong, Zheng, Min

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1582299

Paper Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma

Loh, Jui Wan, Lee, Jing Yi, Lim, Abner Herbert, Guan, Peiyong, Lim, Boon Yee, Kannan, Bavani, Lee, Elizabeth Chun Yong, Gu, Ning Xin, Ko, Tun Kiat, Ng, Cedric Chuan Young, Lim, Jeffrey Chun Tatt, Yeong, Joe, Lim, Jing Quan, Ong, Choon Kiat, Teh, Bin Tean, Chan, Jason Yongsheng · 2023 · Communications Biology · DOI

Full title: Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma

Authors: Loh, Jui Wan, Lee, Jing Yi, Lim, Abner Herbert, Guan, Peiyong, Lim, Boon Yee, Kannan, Bavani, Lee, Elizabeth Chun Yong, Gu, Ning Xin, Ko, Tun Kiat, Ng, Cedric Chuan Young, Lim, Jeffrey Chun Tatt, Yeong, Joe, Lim, Jing Quan, Ong, Choon Kiat, Teh, Bin Tean, Chan, Jason Yongsheng

Year: 2023

Venue: Communications Biology

DOI: https://doi.org/10.1038/s42003-023-04856-5

Paper An Uncommon Case of Myocarditis Secondary to Durvalumab Plus Tremelimumab.

Diaz-Rodriguez, Porfirio E, Muns-Aponte, Claudia M, Velazquez-Acevedo, Sharolyn I, Ortiz-Malave, Cristina M, Acevedo, Jose, Merced-Ortiz, Francisco G · 2023 · Cureus · DOI

Full title: An Uncommon Case of Myocarditis Secondary to Durvalumab Plus Tremelimumab.

Authors: Diaz-Rodriguez, Porfirio E, Muns-Aponte, Claudia M, Velazquez-Acevedo, Sharolyn I, Ortiz-Malave, Cristina M, Acevedo, Jose, Merced-Ortiz, Francisco G

Year: 2023

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.43628

Paper Rational Combination of Parvovirus H1 With CTLA-4 and PD-1 Checkpoint Inhibitors Dampens the Tumor Induced Immune Silencing.

Goepfert, Katrin, Dinsart, Christiane, Rommelaere, Jean, Foerster, Friedrich, Moehler, Markus · 2019 · Frontiers in oncology · DOI

Full title: Rational Combination of Parvovirus H1 With CTLA-4 and PD-1 Checkpoint Inhibitors Dampens the Tumor Induced Immune Silencing.

Authors: Goepfert, Katrin, Dinsart, Christiane, Rommelaere, Jean, Foerster, Friedrich, Moehler, Markus

Year: 2019

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2019.00425

Paper Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways.

Quagliariello, Vincenzo, Passariello, Margherita, Di Mauro, Annabella, Cipullo, Ciro, Paccone, Andrea, Barbieri, Antonio, Palma, Giuseppe, Luciano, Antonio, Buccolo, Simona, Bisceglia, Irma, Canale, Maria Laura, Gallucci, Giuseppina, Inno, Alessandro, De Lorenzo, Claudia, Maurea, Nicola · 2022 · Frontiers in cardiovascular medicine · DOI

Full title: Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways.

Authors: Quagliariello, Vincenzo, Passariello, Margherita, Di Mauro, Annabella, Cipullo, Ciro, Paccone, Andrea, Barbieri, Antonio, Palma, Giuseppe, Luciano, Antonio, Buccolo, Simona, Bisceglia, Irma, Canale, Maria Laura, Gallucci, Giuseppina, Inno, Alessandro, De Lorenzo, Claudia, Maurea, Nicola

Year: 2022

Venue: Frontiers in cardiovascular medicine

DOI: https://doi.org/10.3389/fcvm.2022.930797

Paper Advances in immunotherapy for HNSCC

Lin Dong, Haixia Xu, Xionghao Pang, Yiqian Liu, Meixiang Li · 2025 · Serican Journal of Medicine · DOI

Full title: Advances in immunotherapy for HNSCC

Authors: Lin Dong, Haixia Xu, Xionghao Pang, Yiqian Liu, Meixiang Li

Year: 2025

Venue: Serican Journal of Medicine

DOI: https://doi.org/10.17161/sjm.v2i1.23137

Paper Impact of combinatorial immunotherapies in breast cancer: a systematic review and meta-analysis

Sisodiya, Sandeep, Kasherwal, Vishakha, Rani, Jyoti, Mishra, Neetu, Kumar, Sandeep, Khan, Asiya, Aftab, Mehreen, Negi, Devendra Singh, Singh, Payal, Gupta, Ekta, Tanwar, Pranay, Hussain, Showket · 2024 · Frontiers in Immunology · DOI

Full title: Impact of combinatorial immunotherapies in breast cancer: a systematic review and meta-analysis

Authors: Sisodiya, Sandeep, Kasherwal, Vishakha, Rani, Jyoti, Mishra, Neetu, Kumar, Sandeep, Khan, Asiya, Aftab, Mehreen, Negi, Devendra Singh, Singh, Payal, Gupta, Ekta, Tanwar, Pranay, Hussain, Showket

Year: 2024

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2024.1469441

Paper Immune Checkpoint Inhibitors in Malignant Pleural Mesothelioma: A Systematic Review and Meta-Analysis.

Gemelli, Maria, Cortinovis, Diego Luigi, Baggi, Alice, di Mauro, Pierluigi, Calza, Stefano, Berruti, Alfredo, Grisanti, Salvatore, Rota, Matteo · 2022 · Cancers · DOI

Full title: Immune Checkpoint Inhibitors in Malignant Pleural Mesothelioma: A Systematic Review and Meta-Analysis.

Authors: Gemelli, Maria, Cortinovis, Diego Luigi, Baggi, Alice, di Mauro, Pierluigi, Calza, Stefano, Berruti, Alfredo, Grisanti, Salvatore, Rota, Matteo

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14246063

Paper The future of cancer treatment: immunomodulation, CARs and combination immunotherapy.

Khalil, Danny N, Smith, Eric L, Brentjens, Renier J, Wolchok, Jedd D · 2016 · Nature reviews. Clinical oncology · DOI

Full title: The future of cancer treatment: immunomodulation, CARs and combination immunotherapy.

Authors: Khalil, Danny N, Smith, Eric L, Brentjens, Renier J, Wolchok, Jedd D

Year: 2016

Venue: Nature reviews. Clinical oncology

DOI: https://doi.org/10.1038/nrclinonc.2016.65

Paper Immune Checkpoint Inhibitors and Associated Pituitary Dysfunctions: A Mini-Review.

Fukuda, Izumi · 2023 · Journal of Nippon Medical School = Nippon Ika Daigaku zasshi · DOI

Full title: Immune Checkpoint Inhibitors and Associated Pituitary Dysfunctions: A Mini-Review.

Authors: Fukuda, Izumi

Year: 2023

Venue: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi

DOI: https://doi.org/10.1272/jnms.JNMS.2023_90-215

Paper The anti-PD-1 era of cervical cancer: achievement, opportunity, and challenge

Li, Chen, Cang, Wei, Gu, Yu, Chen, Lihua, Xiang, Yang · 2023 · Frontiers in Immunology · DOI

Full title: The anti-PD-1 era of cervical cancer: achievement, opportunity, and challenge

Authors: Li, Chen, Cang, Wei, Gu, Yu, Chen, Lihua, Xiang, Yang

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1195476

Paper The Cellular and Molecular Immunotherapy in Prostate Cancer.

Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Prabakaran, D S, Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Kandasamy, Sabariswaran, Ramesh, Thiyagarajan, Gopalakrishnan, Abilash Valsala · 2022 · Vaccines · DOI

Full title: The Cellular and Molecular Immunotherapy in Prostate Cancer.

Authors: Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Prabakaran, D S, Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Kandasamy, Sabariswaran, Ramesh, Thiyagarajan, Gopalakrishnan, Abilash Valsala

Year: 2022

Venue: Vaccines

DOI: https://doi.org/10.3390/vaccines10081370

Paper Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.

Zhang, Yan, Du, Xuexiang, Liu, Mingyue, Tang, Fei, Zhang, Peng, Ai, Chunxia, Fields, James K, Sundberg, Eric J, Latinovic, Olga S, Devenport, Martin, Zheng, Pan, Liu, Yang · 2019 · Cell research · DOI

Full title: Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.

Authors: Zhang, Yan, Du, Xuexiang, Liu, Mingyue, Tang, Fei, Zhang, Peng, Ai, Chunxia, Fields, James K, Sundberg, Eric J, Latinovic, Olga S, Devenport, Martin, Zheng, Pan, Liu, Yang

Year: 2019

Venue: Cell research

DOI: https://doi.org/10.1038/s41422-019-0184-1

Paper Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers

Abdo, Joe, Cornell, David L., Mittal, Sumeet K., Agrawal, Devendra K. · 2018 · Frontiers in Oncology · DOI

Full title: Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers

Authors: Abdo, Joe, Cornell, David L., Mittal, Sumeet K., Agrawal, Devendra K.

Year: 2018

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2018.00085

Paper Fc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response

Yang, Ri‐Yao, Huang, Su, Huang, Cai, Fay, Nathan S., Wang, Yanan, Putrevu, Saroja, Wright, Kim, Zaman, Mohd Saif, Cai, Wenyan, Huang, Betty, Wang, Bo, Wright, Meredith S., Hoag, Matthew R., Titong, Allison, Liu, Yue · 2023 · Scientific Reports · DOI

Full title: Fc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response

Authors: Yang, Ri‐Yao, Huang, Su, Huang, Cai, Fay, Nathan S., Wang, Yanan, Putrevu, Saroja, Wright, Kim, Zaman, Mohd Saif, Cai, Wenyan, Huang, Betty, Wang, Bo, Wright, Meredith S., Hoag, Matthew R., Titong, Allison, Liu, Yue

Year: 2023

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-023-36942-3

Paper TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment

Jantz-Naeem, Nouria, Loschinski, Romy, Borucki, Katrin, Mitchell-Flack, Marisa, Böttcher, Martin, Schraven, Burkhart, Mougiakakos, Dimitrios, Kahlfuß, Sascha · 2023 · Frontiers in Oncology · DOI

Full title: TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment

Authors: Jantz-Naeem, Nouria, Loschinski, Romy, Borucki, Katrin, Mitchell-Flack, Marisa, Böttcher, Martin, Schraven, Burkhart, Mougiakakos, Dimitrios, Kahlfuß, Sascha

Year: 2023

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2023.1060112

Paper Dual checkpoint blockade of PD-1 and Tim-3 by engineered hybrid nanovesicles for enhanced cancer immunotherapy

Han Xue, Longxue Guan, Lili Huang, Yuxin Fan, Fenglin Guo, Dandan Liang, Xingang Guan, Guofu Chen · 2025 · Frontiers in Immunology · DOI

Full title: Dual checkpoint blockade of PD-1 and Tim-3 by engineered hybrid nanovesicles for enhanced cancer immunotherapy

Authors: Han Xue, Longxue Guan, Lili Huang, Yuxin Fan, Fenglin Guo, Dandan Liang, Xingang Guan, Guofu Chen

Year: 2025

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2025.1705438

Paper Checkpoint Inhibitors in Dogs: Are We There Yet?

Giuliano, Antonio, Pimentel, Pedro A B, Horta, Rodrigo S · 2024 · Cancers · DOI

Full title: Checkpoint Inhibitors in Dogs: Are We There Yet?

Authors: Giuliano, Antonio, Pimentel, Pedro A B, Horta, Rodrigo S

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16112003

Paper Distinct Dynamics of Migratory Response to PD-1 and CTLA-4 Blockade Reveals New Mechanistic Insights for Potential T-Cell Reinvigoration following Immune Checkpoint Blockade.

Safaeifard, Fateme, Goliaei, Bahram, Aref, Amir R, Foroughmand-Araabi, Mohammad-Hadi, Goliaei, Sama, Lorch, Jochen, Jenkins, Russell W, Barbie, David A, Shariatpanahi, Seyed Peyman, Rüegg, Curzio · 2022 · Cells · DOI

Full title: Distinct Dynamics of Migratory Response to PD-1 and CTLA-4 Blockade Reveals New Mechanistic Insights for Potential T-Cell Reinvigoration following Immune Checkpoint Blockade.

Authors: Safaeifard, Fateme, Goliaei, Bahram, Aref, Amir R, Foroughmand-Araabi, Mohammad-Hadi, Goliaei, Sama, Lorch, Jochen, Jenkins, Russell W, Barbie, David A, Shariatpanahi, Seyed Peyman, Rüegg, Curzio

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11223534

Paper Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma.

Ariyasu, Hiroyuki, Inaba, Hidefumi, Ota, Takayuki, Yamaoka, Hiroyuki, Furukawa, Yasushi, Iwakura, Hiroshi, Doi, Naotaka, Yamamoto, Yuki, Akamizu, Takashi · 2018 · In vivo (Athens, Greece) · DOI

Full title: Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma.

Authors: Ariyasu, Hiroyuki, Inaba, Hidefumi, Ota, Takayuki, Yamaoka, Hiroyuki, Furukawa, Yasushi, Iwakura, Hiroshi, Doi, Naotaka, Yamamoto, Yuki, Akamizu, Takashi

Year: 2018

Venue: In vivo (Athens, Greece)

DOI: https://doi.org/10.21873/invivo.11244

Paper Immune Checkpoints and Their Inhibition in T-Cell Lymphomas.

Seňavová, Jana, Rajmonová, Anežka, Heřman, Václav, Jura, Filip, Veľasová, Adriana, Hamová, Iva, Tkachenko, Anton, Kupcová, Kristýna, Havránek, Ondřej · 2024 · Folia biologica · DOI

Full title: Immune Checkpoints and Their Inhibition in T-Cell Lymphomas.

Authors: Seňavová, Jana, Rajmonová, Anežka, Heřman, Václav, Jura, Filip, Veľasová, Adriana, Hamová, Iva, Tkachenko, Anton, Kupcová, Kristýna, Havránek, Ondřej

Year: 2024

Venue: Folia biologica

DOI: https://doi.org/10.14712/fb2024070030123

Paper Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again.

Bucktrout, Samantha L, Bluestone, Jeffrey A, Ramsdell, Fred · 2018 · Genome medicine · DOI

Full title: Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again.

Authors: Bucktrout, Samantha L, Bluestone, Jeffrey A, Ramsdell, Fred

Year: 2018

Venue: Genome medicine

DOI: https://doi.org/10.1186/s13073-018-0588-4

Paper Anti-CD40 predominates over anti-CTLA-4 to provide enhanced antitumor response of DC-CIK cells in renal cell carcinoma.

Zhang, Ying, Wu, Xiaolong, Sharma, Amit, Weiher, Hans, Schmid, Matthias, Kristiansen, Glen, Schmidt-Wolf, Ingo G H · 2022 · Frontiers in immunology · DOI

Full title: Anti-CD40 predominates over anti-CTLA-4 to provide enhanced antitumor response of DC-CIK cells in renal cell carcinoma.

Authors: Zhang, Ying, Wu, Xiaolong, Sharma, Amit, Weiher, Hans, Schmid, Matthias, Kristiansen, Glen, Schmidt-Wolf, Ingo G H

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.925633

Paper Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle.

Zhuang, Yuan, Liu, Chang, Liu, Jiaqing, Li, Guang · 2020 · OncoTargets and therapy · DOI

Full title: Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle.

Authors: Zhuang, Yuan, Liu, Chang, Liu, Jiaqing, Li, Guang

Year: 2020

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S239398

Paper The great debate at "Melanoma Bridge 2018", Naples, December 1st, 2018.

Ascierto, Paolo A, Bruzzi, Paolo, Eggermont, Alexander, Hamid, Omid, Tawbi, Hussein A, van Akkooi, Alexander, Testori, Alessandro, Caracò, Corrado, Puzanov, Igor, Perrone, Francesco · 2019 · Journal of translational medicine · DOI

Full title: The great debate at "Melanoma Bridge 2018", Naples, December 1st, 2018.

Authors: Ascierto, Paolo A, Bruzzi, Paolo, Eggermont, Alexander, Hamid, Omid, Tawbi, Hussein A, van Akkooi, Alexander, Testori, Alessandro, Caracò, Corrado, Puzanov, Igor, Perrone, Francesco

Year: 2019

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-019-1892-5

Paper Radio-Immune Response Modelling for Spatially Fractionated Radiotherapy

Cho, Young‐Bin, Yoon, Nara, Suh, John H., Jacob, Scott G. · 2023 · DOI

Full title: Radio-Immune Response Modelling for Spatially Fractionated Radiotherapy

Authors: Cho, Young‐Bin, Yoon, Nara, Suh, John H., Jacob, Scott G.

Year: 2023

DOI: https://doi.org/10.1101/2023.04.28.538767

Paper Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice.

Turbitt, William J, Boi, Shannon K, Gibson, Justin T, Orlandella, Rachael M, Norian, Lyse A · 2021 · Cancers · DOI

Full title: Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice.

Authors: Turbitt, William J, Boi, Shannon K, Gibson, Justin T, Orlandella, Rachael M, Norian, Lyse A

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13102295

Paper Myocarditis induced by a novel bifunctional PD-1/CTLA-4 combination antibody: a case report and literature review.

Wei, Chaoyong, Tang, Changli, Zhang, Yao, Tang, Yanxiang, Liu, Yaoqing, Tan, Yuhui, Fu, Yilan · 2025 · BMC cardiovascular disorders · DOI

Full title: Myocarditis induced by a novel bifunctional PD-1/CTLA-4 combination antibody: a case report and literature review.

Authors: Wei, Chaoyong, Tang, Changli, Zhang, Yao, Tang, Yanxiang, Liu, Yaoqing, Tan, Yuhui, Fu, Yilan

Year: 2025

Venue: BMC cardiovascular disorders

DOI: https://doi.org/10.1186/s12872-025-05412-1

Paper The efficacy and safety of combination of PD-1 and CTLA-4 inhibitors: a meta-analysis.

Wu, Kongju, Yi, Ming, Qin, Shuang, Chu, Qian, Zheng, Xinhua, Wu, Kongming · 2019 · Experimental hematology & oncology · DOI

Full title: The efficacy and safety of combination of PD-1 and CTLA-4 inhibitors: a meta-analysis.

Authors: Wu, Kongju, Yi, Ming, Qin, Shuang, Chu, Qian, Zheng, Xinhua, Wu, Kongming

Year: 2019

Venue: Experimental hematology & oncology

DOI: https://doi.org/10.1186/s40164-019-0150-0

Paper Nivolumab monotherapy or combination therapy with ipilimumab for lung cancer: a systemic review and meta-analysis

Huihui Jiang, Aiqun Xu, Wanli Xia, Xingyuan Xia, Pulin Li, Binbin Zhang, Ke Zhu, Sijing Zhou, Ran Wang · 2021 · Cancer Cell International · DOI

Full title: Nivolumab monotherapy or combination therapy with ipilimumab for lung cancer: a systemic review and meta-analysis

Authors: Huihui Jiang, Aiqun Xu, Wanli Xia, Xingyuan Xia, Pulin Li, Binbin Zhang, Ke Zhu, Sijing Zhou, Ran Wang

Year: 2021

Venue: Cancer Cell International

DOI: https://doi.org/10.1186/s12935-021-02100-w

Paper Combination Strategies for PD-1-Based Immunotherapy in Breast Cancer

Xiaofeng Lu · 2025 · Highlights in Science Engineering and Technology · DOI

Full title: Combination Strategies for PD-1-Based Immunotherapy in Breast Cancer

Authors: Xiaofeng Lu

Year: 2025

Venue: Highlights in Science Engineering and Technology

DOI: https://doi.org/10.54097/0fdvyp97

Paper Distributed Biomarker Discovery for Immuno-Oncology

F. Abbas-Aghababazadeh, Kewei Ni, Minoru Nakano, Xin Wang, S. Nair, Nasim Bondar Sahebi, Nadir Sella, Sofija Spasojevic, Jonas Denck, Nicolas Riesterer, Thomas Lehéricy, A. Lorsakul, R. Z. Marandi, Sina Nassiri, Antoaneta Vladimirova, Rubén Armañanzas, John Stagg, Magnus Fontes, Cameron MacPherson, Benjamin Haibe-Kains · 2025 · bioRxiv · DOI

Full title: Distributed Biomarker Discovery for Immuno-Oncology

Authors: F. Abbas-Aghababazadeh, Kewei Ni, Minoru Nakano, Xin Wang, S. Nair, Nasim Bondar Sahebi, Nadir Sella, Sofija Spasojevic, Jonas Denck, Nicolas Riesterer, Thomas Lehéricy, A. Lorsakul, R. Z. Marandi, Sina Nassiri, Antoaneta Vladimirova, Rubén Armañanzas, John Stagg, Magnus Fontes, Cameron MacPherson, Benjamin Haibe-Kains

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.07.25.666789

Paper Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng · 2021 · OncoTargets and Therapy · DOI

Full title: Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Authors: Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng

Year: 2021

Venue: OncoTargets and Therapy

DOI: https://doi.org/10.2147/ott.s269671

Paper The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer.

van Dijk, Nick, Gil-Jimenez, Alberto, Silina, Karina, van Montfoort, Maurits L, Einerhand, Sarah, Jonkman, Lars, Voskuilen, Charlotte S, Peters, Dennis, Sanders, Joyce, Lubeck, Yoni, Broeks, Annegien, Hooijberg, Erik, Vis, Daniel J, van den Broek, Maries, Wessels, Lodewyk F A, van Rhijn, Bas W G, van der Heijden, Michiel S · 2021 · Frontiers in immunology · DOI

Full title: The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer.

Authors: van Dijk, Nick, Gil-Jimenez, Alberto, Silina, Karina, van Montfoort, Maurits L, Einerhand, Sarah, Jonkman, Lars, Voskuilen, Charlotte S, Peters, Dennis, Sanders, Joyce, Lubeck, Yoni, Broeks, Annegien, Hooijberg, Erik, Vis, Daniel J, van den Broek, Maries, Wessels, Lodewyk F A, van Rhijn, Bas W G, van der Heijden, Michiel S

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.793964

Paper Efficacy of dual checkpoint-blockade in solid tumors, part 1

Niedersüß‐Beke, Dora · 2023 · memo - Magazine of European Medical Oncology · DOI

Full title: Efficacy of dual checkpoint-blockade in solid tumors, part 1

Authors: Niedersüß‐Beke, Dora

Year: 2023

Venue: memo - Magazine of European Medical Oncology

DOI: https://doi.org/10.1007/s12254-022-00869-8

Paper Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies.

Park, Kevin, Veena, Mysore S, Shin, Daniel Sanghoon · 2022 · Frontiers in cell and developmental biology · DOI

Full title: Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies.

Authors: Park, Kevin, Veena, Mysore S, Shin, Daniel Sanghoon

Year: 2022

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2022.830208

Paper [Immune-related adverse events by immune checkpoint inhibitors].

Kadono, Takafumi · 2017 · Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology · DOI

Full title: [Immune-related adverse events by immune checkpoint inhibitors].

Authors: Kadono, Takafumi

Year: 2017

Venue: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

DOI: https://doi.org/10.2177/jsci.40.83

Paper Clinical features, diagnostic challenges, and management strategies in checkpoint inhibitor-related pneumonitis.

Chuzi, Sarah, Tavora, Fabio, Cruz, Marcelo, Costa, Ricardo, Chae, Young Kwang, Carneiro, Benedito A, Giles, Francis J · 2017 · Cancer management and research · DOI

Full title: Clinical features, diagnostic challenges, and management strategies in checkpoint inhibitor-related pneumonitis.

Authors: Chuzi, Sarah, Tavora, Fabio, Cruz, Marcelo, Costa, Ricardo, Chae, Young Kwang, Carneiro, Benedito A, Giles, Francis J

Year: 2017

Venue: Cancer management and research

DOI: https://doi.org/10.2147/CMAR.S136818

Paper Combination immunotherapy in hepatocellular carcinoma: synergies among immune checkpoints, TKIs, and chemotherapy.

Dai, Suoyi, Chen, Yuhang, Cai, Wenxun, Dong, Shu, Zhao, Jiangang, Chen, Lianyu, Cheng, Chien-Shan · 2025 · Journal of hematology & oncology · DOI

Full title: Combination immunotherapy in hepatocellular carcinoma: synergies among immune checkpoints, TKIs, and chemotherapy.

Authors: Dai, Suoyi, Chen, Yuhang, Cai, Wenxun, Dong, Shu, Zhao, Jiangang, Chen, Lianyu, Cheng, Chien-Shan

Year: 2025

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-025-01739-6

Paper Double Guard Efficiency and Safety-Overcoming Resistance to Immunotherapy by Blocking or Stimulating Several Immune Checkpoints in Non-Small Cell Lung Cancer Patients.

Kalinka, Ewa, Wojas-Krawczyk, Kamila, Krawczyk, Paweł · 2023 · Cancers · DOI

Full title: Double Guard Efficiency and Safety-Overcoming Resistance to Immunotherapy by Blocking or Stimulating Several Immune Checkpoints in Non-Small Cell Lung Cancer Patients.

Authors: Kalinka, Ewa, Wojas-Krawczyk, Kamila, Krawczyk, Paweł

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15133499

Paper Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer.

Bansal, Dhruv, Reimers, Melissa A, Knoche, Eric M, Pachynski, Russell K · 2021 · Cancers · DOI

Full title: Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer.

Authors: Bansal, Dhruv, Reimers, Melissa A, Knoche, Eric M, Pachynski, Russell K

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13020334

Paper Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.

Crupi, Mathieu J F, Taha, Zaid, Janssen, Thijs J A, Petryk, Julia, Boulton, Stephen, Alluqmani, Nouf, Jirovec, Anna, Kassas, Omar, Khan, Sarwat T, Vallati, Sydney, Lee, Emily, Huang, Ben Zhen, Huh, Michael, Pikor, Larissa, He, Xiaohong, Marius, Ricardo, Austin, Bradley, Duong, Jessie, Pelin, Adrian, Neault, Serge, Azad, Taha, Breitbach, Caroline J, Stojdl, David F, Burgess, Michael F, McComb, Scott, Auer, Rebecca, Diallo, Jean-Simon, Ilkow, Carolina S, Bell, John Cameron · 2022 · Frontiers in immunology · DOI

Full title: Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.

Authors: Crupi, Mathieu J F, Taha, Zaid, Janssen, Thijs J A, Petryk, Julia, Boulton, Stephen, Alluqmani, Nouf, Jirovec, Anna, Kassas, Omar, Khan, Sarwat T, Vallati, Sydney, Lee, Emily, Huang, Ben Zhen, Huh, Michael, Pikor, Larissa, He, Xiaohong, Marius, Ricardo, Austin, Bradley, Duong, Jessie, Pelin, Adrian, Neault, Serge, Azad, Taha, Breitbach, Caroline J, Stojdl, David F, Burgess, Michael F, McComb, Scott, Auer, Rebecca, Diallo, Jean-Simon, Ilkow, Carolina S, Bell, John Cameron

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.1029269

Paper Current Treatment of Melanoma Brain Metastases.

Nowacka, Agnieszka, Fajkiel-Madajczyk, Anna, Ohla, Jakub, Woźniak-Dąbrowska, Kamila, Liss, Sara, Gryczka, Karol, Smuczyński, Wojciech, Ziółkowska, Ewa, Bożiłow, Dominika, Śniegocki, Maciej, Wiciński, Michał · 2023 · Cancers · DOI

Full title: Current Treatment of Melanoma Brain Metastases.

Authors: Nowacka, Agnieszka, Fajkiel-Madajczyk, Anna, Ohla, Jakub, Woźniak-Dąbrowska, Kamila, Liss, Sara, Gryczka, Karol, Smuczyński, Wojciech, Ziółkowska, Ewa, Bożiłow, Dominika, Śniegocki, Maciej, Wiciński, Michał

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15164088

Paper Efficacy and safety of PD-1/PD-L1 and CTLA-4 immune checkpoint inhibitors in the treatment of advanced colorectal cancer: a systematic review and meta-analysis.

Song, Dandan, Hou, Shufu, Ma, Ning, Yan, Bing, Gao, Jing · 2024 · Frontiers in immunology · DOI

Full title: Efficacy and safety of PD-1/PD-L1 and CTLA-4 immune checkpoint inhibitors in the treatment of advanced colorectal cancer: a systematic review and meta-analysis.

Authors: Song, Dandan, Hou, Shufu, Ma, Ning, Yan, Bing, Gao, Jing

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1485303

Paper Immune-Related Adverse Events and Their Association With the Effectiveness of PD-1/PD-L1 Inhibitors in Non-Small Cell Lung Cancer: A Real-World Study From China.

Chen, Xiaoling, Nie, Jun, Dai, Ling, Hu, Weiheng, Zhang, Jie, Han, Jindi, Ma, Xiangjuan, Tian, Guangming, Han, Sen, Wu, Di, Wang, Yang, Long, Jieran, Zhang, Ziran, Fang, Jian · 2021 · Frontiers in oncology · DOI

Full title: Immune-Related Adverse Events and Their Association With the Effectiveness of PD-1/PD-L1 Inhibitors in Non-Small Cell Lung Cancer: A Real-World Study From China.

Authors: Chen, Xiaoling, Nie, Jun, Dai, Ling, Hu, Weiheng, Zhang, Jie, Han, Jindi, Ma, Xiangjuan, Tian, Guangming, Han, Sen, Wu, Di, Wang, Yang, Long, Jieran, Zhang, Ziran, Fang, Jian

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.607531

Paper Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana, Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Jänne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidhu P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok‐Kin, Hammerman, Peter S. · 2016 · Nature Communications · DOI

Full title: Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Authors: Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana, Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Jänne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidhu P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok‐Kin, Hammerman, Peter S.

Year: 2016

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms10501

Paper Mucosal Melanoma: A Rare Entity and Review of the Literature.

Sohal, Raman J, Sohal, Sandeep, Wazir, Ali, Benjamin, Sam · 2020 · Cureus · DOI

Full title: Mucosal Melanoma: A Rare Entity and Review of the Literature.

Authors: Sohal, Raman J, Sohal, Sandeep, Wazir, Ali, Benjamin, Sam

Year: 2020

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.9483

Paper CD137L promotes immune surveillance in melanoma via HLTF regulation.

Liang, Long, Zhu, Lin, Li, Xin, Zhou, Wenbin, Zhang, Yanbin, Hung, Mien-Chie, Zhang, Guanxiong, Chen, Yong, Kuang, Xinwei, Su, Juan, Liu, Jing, Chen, Xiang, Liu, Hong · 2025 · Nature communications · DOI

Full title: CD137L promotes immune surveillance in melanoma via HLTF regulation.

Authors: Liang, Long, Zhu, Lin, Li, Xin, Zhou, Wenbin, Zhang, Yanbin, Hung, Mien-Chie, Zhang, Guanxiong, Chen, Yong, Kuang, Xinwei, Su, Juan, Liu, Jing, Chen, Xiang, Liu, Hong

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-63338-w

Paper Neoadjuvant Immune Checkpoint Inhibitor Therapy in Melanoma: Efficacy, Safety and Timing.

van Akkooi, Alexander C J, Zijlker, Lisanne P, Wouters, Michel W J M · 2022 · BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · DOI

Full title: Neoadjuvant Immune Checkpoint Inhibitor Therapy in Melanoma: Efficacy, Safety and Timing.

Authors: van Akkooi, Alexander C J, Zijlker, Lisanne P, Wouters, Michel W J M

Year: 2022

Venue: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

DOI: https://doi.org/10.1007/s40259-022-00525-x

Paper Modular Nanobody Conjugates with Controlled Topology Using Genetically Encoded Non-canonical Amino Acids

Adomanis, Roman, Phan, Ngoc T., Walter, Gerald, Kimmel, Blaise R. · 2025 · DOI

Full title: Modular Nanobody Conjugates with Controlled Topology Using Genetically Encoded Non-canonical Amino Acids

Authors: Adomanis, Roman, Phan, Ngoc T., Walter, Gerald, Kimmel, Blaise R.

Year: 2025

DOI: https://doi.org/10.1101/2025.11.27.691038

Paper Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer.

Coutzac, Clélia, Jouniaux, Jean-Mehdi, Paci, Angelo, Schmidt, Julien, Mallardo, Domenico, Seck, Atmane, Asvatourian, Vahe, Cassard, Lydie, Saulnier, Patrick, Lacroix, Ludovic, Woerther, Paul-Louis, Vozy, Aurore, Naigeon, Marie, Nebot-Bral, Laetitia, Desbois, Mélanie, Simeone, Ester, Mateus, Christine, Boselli, Lisa, Grivel, Jonathan, Soularue, Emilie, Lepage, Patricia, Carbonnel, Franck, Ascierto, Paolo Antonio, Robert, Caroline, Chaput, Nathalie · 2020 · Nature communications · DOI

Full title: Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer.

Authors: Coutzac, Clélia, Jouniaux, Jean-Mehdi, Paci, Angelo, Schmidt, Julien, Mallardo, Domenico, Seck, Atmane, Asvatourian, Vahe, Cassard, Lydie, Saulnier, Patrick, Lacroix, Ludovic, Woerther, Paul-Louis, Vozy, Aurore, Naigeon, Marie, Nebot-Bral, Laetitia, Desbois, Mélanie, Simeone, Ester, Mateus, Christine, Boselli, Lisa, Grivel, Jonathan, Soularue, Emilie, Lepage, Patricia, Carbonnel, Franck, Ascierto, Paolo Antonio, Robert, Caroline, Chaput, Nathalie

Year: 2020

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-020-16079-x

Paper Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.

Davern, Maria, Donlon, Noel E, O'Connell, Fiona, Gaughan, Caoimhe, O'Donovan, Cillian, McGrath, Jason, Sheppard, Andrew D, Hayes, Conall, King, Ross, Temperley, Hugo, MacLean, Michael, Bulter, Christine, Bhardwaj, Anshul, Moore, Jenny, Donohoe, Claire, Ravi, Narayanasamy, Conroy, Melissa J, Reynolds, John V, Lysaght, Joanne · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.

Authors: Davern, Maria, Donlon, Noel E, O'Connell, Fiona, Gaughan, Caoimhe, O'Donovan, Cillian, McGrath, Jason, Sheppard, Andrew D, Hayes, Conall, King, Ross, Temperley, Hugo, MacLean, Michael, Bulter, Christine, Bhardwaj, Anshul, Moore, Jenny, Donohoe, Claire, Ravi, Narayanasamy, Conroy, Melissa J, Reynolds, John V, Lysaght, Joanne

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-022-04440-0

Paper Checkpoint blockade immunotherapy reshapes the high-dimensional phenotypic heterogeneity of murine intratumoural neoantigen-specific CD8+ T cells.

Fehlings, M, Simoni, Y, Penny, H L, Becht, E, Loh, C Y, Gubin, M M, Ward, J P, Wong, S C, Schreiber, R D, Newell, E W · 2017 · Nature communications · DOI

Full title: Checkpoint blockade immunotherapy reshapes the high-dimensional phenotypic heterogeneity of murine intratumoural neoantigen-specific CD8+ T cells.

Authors: Fehlings, M, Simoni, Y, Penny, H L, Becht, E, Loh, C Y, Gubin, M M, Ward, J P, Wong, S C, Schreiber, R D, Newell, E W

Year: 2017

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-017-00627-z

Paper An oral cancer vaccine using Bifidobacterium vector augments combination of anti-PD-1 and anti-CTLA-4 antibodies in mouse renal cell carcinoma model

Ueki, Hideto, Kitagawa, Koichi, Kato, Mako, Yanase, Shihoko, Okamura, Yasuyoshi, Bando, Yukari, Hara, Takuto, Terakawa, Tomoaki, Furukawa, Junya, Nakano, Yuzo, Fujisawa, Masato, Shirakawa, Toshiro · 2023 · Scientific Reports · DOI

Full title: An oral cancer vaccine using Bifidobacterium vector augments combination of anti-PD-1 and anti-CTLA-4 antibodies in mouse renal cell carcinoma model

Authors: Ueki, Hideto, Kitagawa, Koichi, Kato, Mako, Yanase, Shihoko, Okamura, Yasuyoshi, Bando, Yukari, Hara, Takuto, Terakawa, Tomoaki, Furukawa, Junya, Nakano, Yuzo, Fujisawa, Masato, Shirakawa, Toshiro

Year: 2023

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-023-37234-6

Paper Influence of Microbiome and Antibiotics on the Efficacy of Immune Checkpoint Inhibitors.

Patel, Priyanka, Poudel, Arisa, Kafle, Sunam, Thapa Magar, Manusha, Cancarevic, Ivan · 2021 · Cureus · DOI

Full title: Influence of Microbiome and Antibiotics on the Efficacy of Immune Checkpoint Inhibitors.

Authors: Patel, Priyanka, Poudel, Arisa, Kafle, Sunam, Thapa Magar, Manusha, Cancarevic, Ivan

Year: 2021

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.16829

Paper Concurrent immune checkpoint blockade for enhanced cancer immunotherapy utilizing engineered hybrid nanovesicles.

Liu, Yuxuan, Yang, Fuxu, Li, Zhimin, Wang, Ting, Mu, Yeteng, Fan, Yuxin, Xue, Han, Hu, Xiuli, Guan, Xingang, Feng, Hongxia · 2024 · Frontiers in pharmacology · DOI

Full title: Concurrent immune checkpoint blockade for enhanced cancer immunotherapy utilizing engineered hybrid nanovesicles.

Authors: Liu, Yuxuan, Yang, Fuxu, Li, Zhimin, Wang, Ting, Mu, Yeteng, Fan, Yuxin, Xue, Han, Hu, Xiuli, Guan, Xingang, Feng, Hongxia

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1487940

Paper Research Status and Future Directions of PD-1/CTLA-4 Bispecific Antibodies in the Treatment of Advanced Hepatocellular Carcinoma

Bin Zhao · 2025 · Academic Journal of Science and Technology · DOI

Full title: Research Status and Future Directions of PD-1/CTLA-4 Bispecific Antibodies in the Treatment of Advanced Hepatocellular Carcinoma

Authors: Bin Zhao

Year: 2025

Venue: Academic Journal of Science and Technology

DOI: https://doi.org/10.54097/6k67s850

Paper [Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application].

Deng, Haiyi, Wang, Liqiang, Yang, Yilin, Wu, Jianhui, Zhou, Chengzhi · 2022 · Zhongguo fei ai za zhi = Chinese journal of lung cancer · DOI

Full title: [Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application].

Authors: Deng, Haiyi, Wang, Liqiang, Yang, Yilin, Wu, Jianhui, Zhou, Chengzhi

Year: 2022

Venue: Zhongguo fei ai za zhi = Chinese journal of lung cancer

DOI: https://doi.org/10.3779/j.issn.1009-3419.2021.102.48

Paper Soluble PD-L1: a potential dynamic predictive biomarker for immunotherapy in patients with proficient mismatch repair colorectal cancer.

He, Yinjun, Zhang, Xiang, Zhu, Ming, He, Wenguang, Hua, Hanju, Ye, Feng, Zhou, Xile, Chen, Nan, Li, Yandong, Zhong, Weixiang, Wu, Guosheng, Cai, Hui, Jiang, Weiqin · 2023 · Journal of translational medicine · DOI

Full title: Soluble PD-L1: a potential dynamic predictive biomarker for immunotherapy in patients with proficient mismatch repair colorectal cancer.

Authors: He, Yinjun, Zhang, Xiang, Zhu, Ming, He, Wenguang, Hua, Hanju, Ye, Feng, Zhou, Xile, Chen, Nan, Li, Yandong, Zhong, Weixiang, Wu, Guosheng, Cai, Hui, Jiang, Weiqin

Year: 2023

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-023-03879-0

Paper New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer.

Corke, Lucy, Sacher, Adrian · 2021 · Current oncology (Toronto, Ont.) · DOI

Full title: New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer.

Authors: Corke, Lucy, Sacher, Adrian

Year: 2021

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol29010004

Paper Editorial: Combination immunotherapy and immune response assessment of brain tumours.

Jiang, Haihui · 2025 · Frontiers in immunology · DOI

Full title: Editorial: Combination immunotherapy and immune response assessment of brain tumours.

Authors: Jiang, Haihui

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1639173

Paper Thyroid-related adverse events induced by immune checkpoint inhibitors.

Chera, Alexandra, Stancu, Andreea Lucia, Bucur, Octavian · 2022 · Frontiers in endocrinology · DOI

Full title: Thyroid-related adverse events induced by immune checkpoint inhibitors.

Authors: Chera, Alexandra, Stancu, Andreea Lucia, Bucur, Octavian

Year: 2022

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2022.1010279

Paper Clinical Significance and Molecular Annotation for PD-L1 Negative Advanced Non-Small Cell Lung Cancer with Sensitivity to Responsive to Dual PD-1/CTLA-4 Blockade.

Wang, Li, Liu, Li, Zhao, Jing, Yu, Xin, Su, Chunxia · 2024 · ImmunoTargets and therapy · DOI

Full title: Clinical Significance and Molecular Annotation for PD-L1 Negative Advanced Non-Small Cell Lung Cancer with Sensitivity to Responsive to Dual PD-1/CTLA-4 Blockade.

Authors: Wang, Li, Liu, Li, Zhao, Jing, Yu, Xin, Su, Chunxia

Year: 2024

Venue: ImmunoTargets and therapy

DOI: https://doi.org/10.2147/ITT.S476040

Paper Cadonilimab (PD-1/CTLA-4 bispecific antibody) combination therapy for driver gene-negative advanced NSCLC: a single-center retrospective real-world study.

Zeng, Lulin, Xiang, Yan, Sun, Ao, Lu, Kaihua · 2026 · Frontiers in oncology · DOI

Full title: Cadonilimab (PD-1/CTLA-4 bispecific antibody) combination therapy for driver gene-negative advanced NSCLC: a single-center retrospective real-world study.

Authors: Zeng, Lulin, Xiang, Yan, Sun, Ao, Lu, Kaihua

Year: 2026

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2026.1718151

Paper Tumor microenvironmental modification by the current target therapy for head and neck squamous cell carcinoma.

Okuyama, Kohei, Naruse, Tomofumi, Yanamoto, Souichi · 2023 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Tumor microenvironmental modification by the current target therapy for head and neck squamous cell carcinoma.

Authors: Okuyama, Kohei, Naruse, Tomofumi, Yanamoto, Souichi

Year: 2023

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-023-02691-4

Paper Tumor MHC Expression Guides First-Line Immunotherapy Selection in Melanoma.

Shklovskaya, Elena, Lee, Jenny H, Lim, Su Yin, Stewart, Ashleigh, Pedersen, Bernadette, Ferguson, Peter, Saw, Robyn Pm, Thompson, John F, Shivalingam, Brindha, Carlino, Matteo S, Scolyer, Richard A, Menzies, Alexander M, Long, Georgina V, Kefford, Richard F, Rizos, Helen · 2020 · Cancers · DOI

Full title: Tumor MHC Expression Guides First-Line Immunotherapy Selection in Melanoma.

Authors: Shklovskaya, Elena, Lee, Jenny H, Lim, Su Yin, Stewart, Ashleigh, Pedersen, Bernadette, Ferguson, Peter, Saw, Robyn Pm, Thompson, John F, Shivalingam, Brindha, Carlino, Matteo S, Scolyer, Richard A, Menzies, Alexander M, Long, Georgina V, Kefford, Richard F, Rizos, Helen

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12113374

Paper Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy.

Widmann, Gerlig, Nguyen, Van Anh, Plaickner, Julian, Jaschke, Werner · 2016 · Current radiology reports · DOI

Full title: Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy.

Authors: Widmann, Gerlig, Nguyen, Van Anh, Plaickner, Julian, Jaschke, Werner

Year: 2016

Venue: Current radiology reports

DOI: https://doi.org/10.1007/s40134-017-0256-2

Paper Case report: Is severe toxicity the price to pay for high sensitivity to checkpoint inhibitors immunotherapy in desmoplastic melanoma?

Squicciarini, Teresa, Villani, Rossella, Apollonio, Benedetta, Fucci, Livia, Zambetti, Milena, Rossini, Michele, Pinto, Rosamaria, Tommasi, Stefania, De Roma, Ileana, Strippoli, Sabino, Guida, Michele · 2024 · Frontiers in immunology · DOI

Full title: Case report: Is severe toxicity the price to pay for high sensitivity to checkpoint inhibitors immunotherapy in desmoplastic melanoma?

Authors: Squicciarini, Teresa, Villani, Rossella, Apollonio, Benedetta, Fucci, Livia, Zambetti, Milena, Rossini, Michele, Pinto, Rosamaria, Tommasi, Stefania, De Roma, Ileana, Strippoli, Sabino, Guida, Michele

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1369531

Paper TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

Itay Raphael, Rajeev Kumar, L. McCarl, Karsen E. Shoger, Lin Wang, Poorva Sandlesh, Chaim T Sneiderman, Jordan Allen, Shuyan Zhai, Marissa Campagna, Alexandra E Foster, T. Bruno, S. Agnihotri, Baoli Hu, Brandyn Castro, F. Lieberman, A. Broniscer, A. Diaz, N. Amankulor, D. Rajasundaram, I. Pollack, G. Kohanbash · 2021 · Frontiers in Immunology · DOI

Full title: TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

Authors: Itay Raphael, Rajeev Kumar, L. McCarl, Karsen E. Shoger, Lin Wang, Poorva Sandlesh, Chaim T Sneiderman, Jordan Allen, Shuyan Zhai, Marissa Campagna, Alexandra E Foster, T. Bruno, S. Agnihotri, Baoli Hu, Brandyn Castro, F. Lieberman, A. Broniscer, A. Diaz, N. Amankulor, D. Rajasundaram, I. Pollack, G. Kohanbash

Year: 2021

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2021.637146

Paper An Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma.

Davis, Alexander, Ke, Helen, Kao, Steven, Pavlakis, Nick · 2022 · Lung Cancer (Auckland, N.Z.) · DOI

Full title: An Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma.

Authors: Davis, Alexander, Ke, Helen, Kao, Steven, Pavlakis, Nick

Year: 2022

Venue: Lung Cancer (Auckland, N.Z.)

DOI: https://doi.org/10.2147/LCTT.S288535

Paper Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma.

Wang, Yongdan, Li, Pan, Mao, Shuai, Mo, Zhuomao, Cao, Zhirui, Luo, Jin, Zhou, Meiling, Liu, Xifeng, Zhang, Shijun, Yu, Ling · 2021 · Frontiers in pharmacology · DOI

Full title: Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma.

Authors: Wang, Yongdan, Li, Pan, Mao, Shuai, Mo, Zhuomao, Cao, Zhirui, Luo, Jin, Zhou, Meiling, Liu, Xifeng, Zhang, Shijun, Yu, Ling

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.757194

Paper Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.

Mendis, S, Gill, S · 2020 · Current oncology (Toronto, Ont.) · DOI

Full title: Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.

Authors: Mendis, S, Gill, S

Year: 2020

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3747/co.27.5095

Paper Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy

Li, Yiliang, Patel, Sapna P., Roszik, Jason, Qin, Yong · 2018 · Frontiers in Immunology · DOI

Full title: Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy

Authors: Li, Yiliang, Patel, Sapna P., Roszik, Jason, Qin, Yong

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.01591

Paper RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.

Tentler, John J, Lang, Julie, Capasso, Anna, Kim, Deog Joong, Benaim, Ely, Lee, Young B, Eisen, Andrew, Bagby, Stacey M, Hartman, Sarah J, Yacob, Betelehem W, Gittleman, Brian, Pitts, Todd M, Pelanda, Roberta, Eckhardt, S Gail, Diamond, Jennifer R · 2020 · BMC cancer · DOI

Full title: RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.

Authors: Tentler, John J, Lang, Julie, Capasso, Anna, Kim, Deog Joong, Benaim, Ely, Lee, Young B, Eisen, Andrew, Bagby, Stacey M, Hartman, Sarah J, Yacob, Betelehem W, Gittleman, Brian, Pitts, Todd M, Pelanda, Roberta, Eckhardt, S Gail, Diamond, Jennifer R

Year: 2020

Venue: BMC cancer

DOI: https://doi.org/10.1186/s12885-020-07500-1

Paper Review of PD-1/PD-L1 Inhibitors in Metastatic dMMR/MSI-H Colorectal Cancer.

Oliveira, André F, Bretes, Luís, Furtado, Irene · 2019 · Frontiers in oncology · DOI

Full title: Review of PD-1/PD-L1 Inhibitors in Metastatic dMMR/MSI-H Colorectal Cancer.

Authors: Oliveira, André F, Bretes, Luís, Furtado, Irene

Year: 2019

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2019.00396

Paper Costimulatory and coinhibitory immune checkpoint receptors in head and neck cancer: unleashing immune responses through therapeutic combinations.

Davis, Ruth J, Ferris, Robert L, Schmitt, Nicole C · 2016 · Cancers of the head & neck · DOI

Full title: Costimulatory and coinhibitory immune checkpoint receptors in head and neck cancer: unleashing immune responses through therapeutic combinations.

Authors: Davis, Ruth J, Ferris, Robert L, Schmitt, Nicole C

Year: 2016

Venue: Cancers of the head & neck

DOI: https://doi.org/10.1186/s41199-016-0013-x

Paper Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.

Kiaie, Seyed Hossein, Salehi-Shadkami, Hossein, Sanaei, Mohammad Javad, Azizi, Marzieh, Shokrollahi Barough, Mahdieh, Nasr, Mohammad Sadegh, Sheibani, Mohammad · 2023 · Journal of nanobiotechnology · DOI

Full title: Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.

Authors: Kiaie, Seyed Hossein, Salehi-Shadkami, Hossein, Sanaei, Mohammad Javad, Azizi, Marzieh, Shokrollahi Barough, Mahdieh, Nasr, Mohammad Sadegh, Sheibani, Mohammad

Year: 2023

Venue: Journal of nanobiotechnology

DOI: https://doi.org/10.1186/s12951-023-02083-y

Paper Advancing non-small cell lung cancer treatment: the power of combination immunotherapies

Wu, Yuanlin, Yu, Guangmao, Jin, Ketao, Qian, Jun · 2024 · Frontiers in Immunology · DOI

Full title: Advancing non-small cell lung cancer treatment: the power of combination immunotherapies

Authors: Wu, Yuanlin, Yu, Guangmao, Jin, Ketao, Qian, Jun

Year: 2024

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2024.1349502

Paper Immunotherapy-Induced Anterior Hypophysitis.

Pachika, Pranali S, Khanam, Razwana, Faisal, Seemal, Ahmad, Tahreem, Chandrasekhara Pillai, Anjana · 2021 · Cureus · DOI

Full title: Immunotherapy-Induced Anterior Hypophysitis.

Authors: Pachika, Pranali S, Khanam, Razwana, Faisal, Seemal, Ahmad, Tahreem, Chandrasekhara Pillai, Anjana

Year: 2021

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.16538

Paper Plasma GDF15 levels associated with circulating immune cells predict the efficacy of PD-1/PD-L1 inhibitor treatment and prognosis in patients with advanced non-small cell lung cancer.

Hong, Green, Sun, Pureum, Chung, Chaeuk, Park, Dongil, Lee, Song-I, Kim, Nayoung, Lee, Seong Eun, Lee, Jeong Eun, Kang, Yea Eun, Kang, Da Hyun · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Plasma GDF15 levels associated with circulating immune cells predict the efficacy of PD-1/PD-L1 inhibitor treatment and prognosis in patients with advanced non-small cell lung cancer.

Authors: Hong, Green, Sun, Pureum, Chung, Chaeuk, Park, Dongil, Lee, Song-I, Kim, Nayoung, Lee, Seong Eun, Lee, Jeong Eun, Kang, Yea Eun, Kang, Da Hyun

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-022-04500-5

Paper Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies.

Damei, Isabelle, Caidi, Aziza, Auclin, Edouard, Adam, Julien, Mella, Sébastien, Hasan, Milena, Tartour, Eric, Robert, Caroline, Corgnac, Stéphanie, Mami-Chouaib, Fathia · 2025 · Nature communications · DOI

Full title: Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies.

Authors: Damei, Isabelle, Caidi, Aziza, Auclin, Edouard, Adam, Julien, Mella, Sébastien, Hasan, Milena, Tartour, Eric, Robert, Caroline, Corgnac, Stéphanie, Mami-Chouaib, Fathia

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-60657-w

Paper Phenotypic and Proteomic Analysis Identifies Hallmarks of Blood Circulating Extracellular Vesicles in NSCLC Responders to Immune Checkpoint Inhibitors

D. Brocco, P. Lanuti, D. Pieragostino, M. Cufaro, P. Simeone, G. Bologna, P. Di Marino, M. De Tursi, A. Grassadonia, L. Irtelli, L. De Lellis, S. Veschi, Rosalba Florio, L. Federici, M. Marchisio, S. Miscia, A. Cama, N. Tinari, P. Del Boccio · 2021 · Cancers · DOI

Full title: Phenotypic and Proteomic Analysis Identifies Hallmarks of Blood Circulating Extracellular Vesicles in NSCLC Responders to Immune Checkpoint Inhibitors

Authors: D. Brocco, P. Lanuti, D. Pieragostino, M. Cufaro, P. Simeone, G. Bologna, P. Di Marino, M. De Tursi, A. Grassadonia, L. Irtelli, L. De Lellis, S. Veschi, Rosalba Florio, L. Federici, M. Marchisio, S. Miscia, A. Cama, N. Tinari, P. Del Boccio

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13040585

Paper Lymphocyte-activating gene 3 expression in tumor cells predicts immune checkpoint inhibitor response in triple negative breast cancer.

Kim, Ji-Yeon, Kim, Jeehyun, Cho, Eun Yoon, Park, Yeon Hee, Ahn, Jin Seok, Kim, Kyoung-Mee, Im, Young-Hyuck · 2023 · Frontiers in oncology · DOI

Full title: Lymphocyte-activating gene 3 expression in tumor cells predicts immune checkpoint inhibitor response in triple negative breast cancer.

Authors: Kim, Ji-Yeon, Kim, Jeehyun, Cho, Eun Yoon, Park, Yeon Hee, Ahn, Jin Seok, Kim, Kyoung-Mee, Im, Young-Hyuck

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1146934

Paper Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity

Zhong, Zhenwei, Zhang, Mengyao, Ning, Yanan, Mao, Guanchao, Li, Xiaopei, Deng, Qi, Chen, Xiaorui, Zuo, Dongliang, Zhao, Xiangyu, Xie, Ermin, Wang, Huajing, Guo, Lina, Li, Bohua, Xiao, Kai, He, Xiaowen · 2022 · Scientific Reports · DOI

Full title: Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity

Authors: Zhong, Zhenwei, Zhang, Mengyao, Ning, Yanan, Mao, Guanchao, Li, Xiaopei, Deng, Qi, Chen, Xiaorui, Zuo, Dongliang, Zhao, Xiangyu, Xie, Ermin, Wang, Huajing, Guo, Lina, Li, Bohua, Xiao, Kai, He, Xiaowen

Year: 2022

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-022-22975-7

Paper Revising the Landscape of Cytokine-Induced Killer Cell Therapy in Lung Cancer: Focus on Immune Checkpoint Inhibitors.

Vaseq, Rohulla, Sharma, Amit, Li, Yutao, Schmidt-Wolf, Ingo G H · 2023 · International journal of molecular sciences · DOI

Full title: Revising the Landscape of Cytokine-Induced Killer Cell Therapy in Lung Cancer: Focus on Immune Checkpoint Inhibitors.

Authors: Vaseq, Rohulla, Sharma, Amit, Li, Yutao, Schmidt-Wolf, Ingo G H

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24065626

Paper PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake.

Zhang, Jian-Ye, Yan, Yan-Yan, Li, Jia-Jun, Adhikari, Rameshwar, Fu, Li-Wu · 2020 · Frontiers in pharmacology · DOI

Full title: PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake.

Authors: Zhang, Jian-Ye, Yan, Yan-Yan, Li, Jia-Jun, Adhikari, Rameshwar, Fu, Li-Wu

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00722

Paper Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.

Wang, Xinyao, Zhang, Yuli, Xie, Wei, Liu, Haiying, Cui, Lianghui, Feng, Min · 2025 · Frontiers in oncology · DOI

Full title: Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.

Authors: Wang, Xinyao, Zhang, Yuli, Xie, Wei, Liu, Haiying, Cui, Lianghui, Feng, Min

Year: 2025

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2025.1659897

Paper Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy.

Xu, Shuang, Luo, Yang, He, Yuzhu, Chen, Yuxiang, Qin, Fengfeng, Hu, Wenjian · 2025 · Discover oncology · DOI

Full title: Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy.

Authors: Xu, Shuang, Luo, Yang, He, Yuzhu, Chen, Yuxiang, Qin, Fengfeng, Hu, Wenjian

Year: 2025

Venue: Discover oncology

DOI: https://doi.org/10.1007/s12672-025-02673-2

Paper Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

Luheshi, Nadia M, Coates-Ulrichsen, Jane, Harper, James, Mullins, Stefanie, Sulikowski, Michal G, Martin, Philip, Brown, Lee, Lewis, Arthur, Davies, Gareth, Morrow, Michelle, Wilkinson, Robert W · 2016 · Oncotarget · DOI

Full title: Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

Authors: Luheshi, Nadia M, Coates-Ulrichsen, Jane, Harper, James, Mullins, Stefanie, Sulikowski, Michal G, Martin, Philip, Brown, Lee, Lewis, Arthur, Davies, Gareth, Morrow, Michelle, Wilkinson, Robert W

Year: 2016

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.7610

Paper Molecular Mechanisms of Cutaneous Immune-Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitors.

Teng, Yi-Shan, Yu, Sebastian · 2023 · Current oncology (Toronto, Ont.) · DOI

Full title: Molecular Mechanisms of Cutaneous Immune-Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitors.

Authors: Teng, Yi-Shan, Yu, Sebastian

Year: 2023

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol30070498

Paper Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei · 2021 · Frontiers in Oncology · DOI

Full title: Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Authors: Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.628124

Paper Combination of PD-1/PD-L1 and CTLA-4 inhibitors in the treatment of cancer - a brief update.

Park, Johan, Skålhegg, Bjørn Steen · 2025 · Frontiers in immunology · DOI

Full title: Combination of PD-1/PD-L1 and CTLA-4 inhibitors in the treatment of cancer - a brief update.

Authors: Park, Johan, Skålhegg, Bjørn Steen

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1680838

Paper The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.

Karwacka, Izabela, Obołończyk, Łukasz, Kaniuka-Jakubowska, Sonia, Sworczak, Krzysztof · 2021 · Biomedicines · DOI

Full title: The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.

Authors: Karwacka, Izabela, Obołończyk, Łukasz, Kaniuka-Jakubowska, Sonia, Sworczak, Krzysztof

Year: 2021

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines9020098

Paper The Heart of the Matter: Immune Checkpoint Inhibitors and Immune-Related Adverse Events on the Cardiovascular System.

Green, Chase E, Chacon, Jessica, Godinich, Brandon M, Hock, Rivers, Kiesewetter, Maria, Raynor, Mark, Marwaha, Komal, Maharaj, Satish, Holland, Nathan · 2023 · Cancers · DOI

Full title: The Heart of the Matter: Immune Checkpoint Inhibitors and Immune-Related Adverse Events on the Cardiovascular System.

Authors: Green, Chase E, Chacon, Jessica, Godinich, Brandon M, Hock, Rivers, Kiesewetter, Maria, Raynor, Mark, Marwaha, Komal, Maharaj, Satish, Holland, Nathan

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15245707

Paper A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.

Du, Xuexiang, Tang, Fei, Liu, Mingyue, Su, Juanjuan, Zhang, Yan, Wu, Wei, Devenport, Martin, Lazarski, Christopher A, Zhang, Peng, Wang, Xu, Ye, Peiying, Wang, Changyu, Hwang, Eugene, Zhu, Tinghui, Xu, Ting, Zheng, Pan, Liu, Yang · 2018 · Cell research · DOI

Full title: A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.

Authors: Du, Xuexiang, Tang, Fei, Liu, Mingyue, Su, Juanjuan, Zhang, Yan, Wu, Wei, Devenport, Martin, Lazarski, Christopher A, Zhang, Peng, Wang, Xu, Ye, Peiying, Wang, Changyu, Hwang, Eugene, Zhu, Tinghui, Xu, Ting, Zheng, Pan, Liu, Yang

Year: 2018

Venue: Cell research

DOI: https://doi.org/10.1038/s41422-018-0011-0

Paper Targeting lymph node delivery with nanovaccines for cancer immunotherapy: recent advances and future directions

Li, Yueyi, Shen, Li, Jiang, Zedong, Tan, Keqin, Meng, Yuanling, Zhang, Dingyi, Ma, Xuelei · 2023 · Journal of Nanobiotechnology · DOI

Full title: Targeting lymph node delivery with nanovaccines for cancer immunotherapy: recent advances and future directions

Authors: Li, Yueyi, Shen, Li, Jiang, Zedong, Tan, Keqin, Meng, Yuanling, Zhang, Dingyi, Ma, Xuelei

Year: 2023

Venue: Journal of Nanobiotechnology

DOI: https://doi.org/10.1186/s12951-023-01977-1

Paper Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma.

Petrova, Vera, Arkhypov, Ihor, Weber, Rebekka, Groth, Christopher, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor · 2020 · International journal of molecular sciences · DOI

Full title: Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma.

Authors: Petrova, Vera, Arkhypov, Ihor, Weber, Rebekka, Groth, Christopher, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21072367

Paper Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies.

Tanaka, Ichidai, Koyama, Junji, Itoigawa, Hideyuki, Hayai, Shunsaku, Morise, Masahiro · 2023 · Frontiers in oncology · DOI

Full title: Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies.

Authors: Tanaka, Ichidai, Koyama, Junji, Itoigawa, Hideyuki, Hayai, Shunsaku, Morise, Masahiro

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1249237

Paper Immune Checkpoint Molecules in Hodgkin Lymphoma and Other Hematological Malignancies.

Alibrahim, Mohamed Nazem, Carbone, Antonino, Alsaleh, Noor, Gloghini, Annunziata · 2025 · Cancers · DOI

Full title: Immune Checkpoint Molecules in Hodgkin Lymphoma and Other Hematological Malignancies.

Authors: Alibrahim, Mohamed Nazem, Carbone, Antonino, Alsaleh, Noor, Gloghini, Annunziata

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17142292

Paper Small-Cell Lung Cancer-An Update on Targeted and Immunotherapies.

McNamee, Nicholas, da Silva, Ines Pires, Nagrial, Adnan, Gao, Bo · 2023 · International journal of molecular sciences · DOI

Full title: Small-Cell Lung Cancer-An Update on Targeted and Immunotherapies.

Authors: McNamee, Nicholas, da Silva, Ines Pires, Nagrial, Adnan, Gao, Bo

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24098129

Paper Acute interstitial nephritis related to immune checkpoint inhibitors.

Belliere, Julie, Meyer, Nicolas, Mazieres, Julien, Ollier, Sylvie, Boulinguez, Serge, Delas, Audrey, Ribes, David, Faguer, Stanislas · 2016 · British journal of cancer · DOI

Full title: Acute interstitial nephritis related to immune checkpoint inhibitors.

Authors: Belliere, Julie, Meyer, Nicolas, Mazieres, Julien, Ollier, Sylvie, Boulinguez, Serge, Delas, Audrey, Ribes, David, Faguer, Stanislas

Year: 2016

Venue: British journal of cancer

DOI: https://doi.org/10.1038/bjc.2016.358

Paper Liver graft rejection following immune checkpoint inhibitors treatment: a review.

Hu, Bo, Yang, Xiao-Bo, Sang, Xin-Ting · 2019 · Medical oncology (Northwood, London, England) · DOI

Full title: Liver graft rejection following immune checkpoint inhibitors treatment: a review.

Authors: Hu, Bo, Yang, Xiao-Bo, Sang, Xin-Ting

Year: 2019

Venue: Medical oncology (Northwood, London, England)

DOI: https://doi.org/10.1007/s12032-019-1316-7

Paper Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

Chae, Young Kwang, Chung, Su Yun, Davis, Andrew A., Carneiro, Benedito A., Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Giles, Francis J. · 2015 · Oncotarget · DOI

Full title: Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

Authors: Chae, Young Kwang, Chung, Su Yun, Davis, Andrew A., Carneiro, Benedito A., Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Giles, Francis J.

Year: 2015

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.5076

Paper Clinical outcomes and influencing factors of PD-1/PD-L1 in hepatocellular carcinoma.

Wang, Jiting, Li, Jun, Tang, Guiju, Tian, Yuan, Su, Song, Li, Yaling · 2021 · Oncology letters · DOI

Full title: Clinical outcomes and influencing factors of PD-1/PD-L1 in hepatocellular carcinoma.

Authors: Wang, Jiting, Li, Jun, Tang, Guiju, Tian, Yuan, Su, Song, Li, Yaling

Year: 2021

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2021.12540

Paper Adverse events of neoadjuvant combination immunotherapy for resectable cancer patients: a systematic review and meta-analysis.

Feng, Yuqian, Guo, Kaibo, Jin, Huimin, Jiang, Jing, Wang, Menglei, Lin, Shengyou · 2023 · Frontiers in immunology · DOI

Full title: Adverse events of neoadjuvant combination immunotherapy for resectable cancer patients: a systematic review and meta-analysis.

Authors: Feng, Yuqian, Guo, Kaibo, Jin, Huimin, Jiang, Jing, Wang, Menglei, Lin, Shengyou

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1269067

Paper The Evolving Landscape of Immunotherapy-Based Combinations for Frontline Treatment of Advanced Renal Cell Carcinoma.

Amin, Asim, Hammers, Hans · 2018 · Frontiers in immunology · DOI

Full title: The Evolving Landscape of Immunotherapy-Based Combinations for Frontline Treatment of Advanced Renal Cell Carcinoma.

Authors: Amin, Asim, Hammers, Hans

Year: 2018

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2018.03120

Paper Assessment of Variables Related to the Risk of Severe Adverse Events in Cutaneous Melanoma Patients Treated with Immune Checkpoint Inhibitors.

Trichkova, Kremena Petrova, Görtler, Franziska, Bjørge, Line, Schuster, Cornelia · 2024 · Cancers · DOI

Full title: Assessment of Variables Related to the Risk of Severe Adverse Events in Cutaneous Melanoma Patients Treated with Immune Checkpoint Inhibitors.

Authors: Trichkova, Kremena Petrova, Görtler, Franziska, Bjørge, Line, Schuster, Cornelia

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16020250

Paper Bridging Immune Evasion and Vascular Dynamics for Novel Therapeutic Frontiers in Hepatocellular Carcinoma.

Wu, Sulin, Anand, Namrata, Guo, Zhoubo, Li, Mingyang, Santiago Figueroa, Marcos, Jung, Lauren, Kelly, Sarah, Franses, Joseph W · 2025 · Cancers · DOI

Full title: Bridging Immune Evasion and Vascular Dynamics for Novel Therapeutic Frontiers in Hepatocellular Carcinoma.

Authors: Wu, Sulin, Anand, Namrata, Guo, Zhoubo, Li, Mingyang, Santiago Figueroa, Marcos, Jung, Lauren, Kelly, Sarah, Franses, Joseph W

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17111860

Paper Immunotherapy of osteosarcoma based on immune microenvironment modulation

Lian, Heping, Zhang, Jiakui, Hou, Shijiao, Ma, Shuang, Yu, Jiachen, Zhao, Wei, Zhao, Duoyi, Zhang, Zhiyu · 2025 · Frontiers in Immunology · DOI

Full title: Immunotherapy of osteosarcoma based on immune microenvironment modulation

Authors: Lian, Heping, Zhang, Jiakui, Hou, Shijiao, Ma, Shuang, Yu, Jiachen, Zhao, Wei, Zhao, Duoyi, Zhang, Zhiyu

Year: 2025

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2024.1498060

Paper Efficacy of PD-1/PD-L1 inhibitors against pretreated advanced cancer: a systematic review and meta-analysis.

Hu, Hao, Zhu, Qian, Luo, Xian Shi, Yang, Xiong Wen, Wang, Hai Dong, Guo, Chang Ying · 2018 · Oncotarget · DOI

Full title: Efficacy of PD-1/PD-L1 inhibitors against pretreated advanced cancer: a systematic review and meta-analysis.

Authors: Hu, Hao, Zhu, Qian, Luo, Xian Shi, Yang, Xiong Wen, Wang, Hai Dong, Guo, Chang Ying

Year: 2018

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.24163

Paper Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies.

Wang, Dongxu, Lin, Jianzhen, Yang, Xu, Long, Junyu, Bai, Yi, Yang, Xiaobo, Mao, Yilei, Sang, Xinting, Seery, Samuel, Zhao, Haitao · 2019 · Journal of hematology & oncology · DOI

Full title: Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies.

Authors: Wang, Dongxu, Lin, Jianzhen, Yang, Xu, Long, Junyu, Bai, Yi, Yang, Xiaobo, Mao, Yilei, Sang, Xinting, Seery, Samuel, Zhao, Haitao

Year: 2019

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-019-0730-9

Paper Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events.

Poto, Remo, Troiani, Teresa, Criscuolo, Gjada, Marone, Giancarlo, Ciardiello, Fortunato, Tocchetti, Carlo Gabriele, Varricchi, Gilda · 2022 · Frontiers in immunology · DOI

Full title: Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events.

Authors: Poto, Remo, Troiani, Teresa, Criscuolo, Gjada, Marone, Giancarlo, Ciardiello, Fortunato, Tocchetti, Carlo Gabriele, Varricchi, Gilda

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.804597

Paper The appropriate frequency and function of decidual Tim-3+CTLA-4+CD8+ T cells are important in maintaining normal pregnancy.

Wang, Songcun, Sun, Fengrun, Li, Mengdie, Qian, Jinfeng, Chen, Chunqin, Wang, Mingyan, Zang, Xingxing, Li, Dajin, Yu, Min, Du, Meirong · 2019 · Cell death & disease · DOI

Full title: The appropriate frequency and function of decidual Tim-3+CTLA-4+CD8+ T cells are important in maintaining normal pregnancy.

Authors: Wang, Songcun, Sun, Fengrun, Li, Mengdie, Qian, Jinfeng, Chen, Chunqin, Wang, Mingyan, Zang, Xingxing, Li, Dajin, Yu, Min, Du, Meirong

Year: 2019

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-019-1642-x

Paper Immune checkpoint inhibitors in cancer therapy.

Webb, Eika S, Liu, Peng, Baleeiro, Renato, Lemoine, Nicholas R, Yuan, Ming, Wang, Yao-He · 2018 · Journal of biomedical research · DOI

Full title: Immune checkpoint inhibitors in cancer therapy.

Authors: Webb, Eika S, Liu, Peng, Baleeiro, Renato, Lemoine, Nicholas R, Yuan, Ming, Wang, Yao-He

Year: 2018

Venue: Journal of biomedical research

DOI: https://doi.org/10.7555/JBR.31.20160168

Paper Two Malignancies With Differential Responses to Immune Checkpoint Inhibitors: A Case Report.

Han, Se Young, Jahagirdar, Balkrishna N, Dudek, Arkadiusz Z · 2020 · Anticancer research · DOI

Full title: Two Malignancies With Differential Responses to Immune Checkpoint Inhibitors: A Case Report.

Authors: Han, Se Young, Jahagirdar, Balkrishna N, Dudek, Arkadiusz Z

Year: 2020

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.14255

Paper Therapeutic cancer vaccines and combination immunotherapies involving vaccination

Kaliński, Paweł, NGUYEN, TRANG, Urban, Julie · 2014 · ImmunoTargets and Therapy · DOI

Full title: Therapeutic cancer vaccines and combination immunotherapies involving vaccination

Authors: Kaliński, Paweł, NGUYEN, TRANG, Urban, Julie

Year: 2014

Venue: ImmunoTargets and Therapy

DOI: https://doi.org/10.2147/itt.s40264

Paper A Changing of the Guard: Immune Checkpoint Inhibitors With and Without Chemotherapy as First Line Treatment for Metastatic Non-small Cell Lung Cancer

Pacheco, Jose M., Camidge, D. Ross, Doebele, Robert C., Schenk, Erin L. · 2019 · Frontiers in Oncology · DOI

Full title: A Changing of the Guard: Immune Checkpoint Inhibitors With and Without Chemotherapy as First Line Treatment for Metastatic Non-small Cell Lung Cancer

Authors: Pacheco, Jose M., Camidge, D. Ross, Doebele, Robert C., Schenk, Erin L.

Year: 2019

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2019.00195

Paper A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer.

Fu, Jie, Yan, Yi-Dan, Wan, Xu, Sun, Xiao-Fan, Ma, Xiu-Mei, Su, Ying-Jie · 2024 · Frontiers in pharmacology · DOI

Full title: A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer.

Authors: Fu, Jie, Yan, Yi-Dan, Wan, Xu, Sun, Xiao-Fan, Ma, Xiu-Mei, Su, Ying-Jie

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1516735

Paper Immune Checkpoint Inhibitors as Monotherapy or Within a Combinatorial Strategy in Advanced Hepatocellular Carcinoma

Guardascione, Michela, Toffoli, Giuseppe · 2020 · International Journal of Molecular Sciences · DOI

Full title: Immune Checkpoint Inhibitors as Monotherapy or Within a Combinatorial Strategy in Advanced Hepatocellular Carcinoma

Authors: Guardascione, Michela, Toffoli, Giuseppe

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21176302

Paper Transglutaminase 2 in breast cancer metastasis and drug resistance.

Li, Mengxin, Wang, Xuanzhong, Hong, Jinghui, Mao, Juanjuan, Chen, Jiasi, Chen, Xuyang, Du, Ye, Song, Dong · 2024 · Frontiers in cell and developmental biology · DOI

Full title: Transglutaminase 2 in breast cancer metastasis and drug resistance.

Authors: Li, Mengxin, Wang, Xuanzhong, Hong, Jinghui, Mao, Juanjuan, Chen, Jiasi, Chen, Xuyang, Du, Ye, Song, Dong

Year: 2024

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2024.1485258

Paper Is There Still Room for Cancer Vaccines at the Era of Checkpoint Inhibitors.

Karaki, Soumaya, Anson, Marie, Tran, Thi, Giusti, Delphine, Blanc, Charlotte, Oudard, Stephane, Tartour, Eric · 2016 · Vaccines · DOI

Full title: Is There Still Room for Cancer Vaccines at the Era of Checkpoint Inhibitors.

Authors: Karaki, Soumaya, Anson, Marie, Tran, Thi, Giusti, Delphine, Blanc, Charlotte, Oudard, Stephane, Tartour, Eric

Year: 2016

Venue: Vaccines

DOI: https://doi.org/10.3390/vaccines4040037

Paper Soluble CD27 differentially predicts resistance to anti-PD1 alone but not with anti-CTLA-4 in melanoma.

Sam, Ikuan, Benhamouda, Nadine, Biard, Lucie, Da Meda, Laetitia, Desseaux, Kristell, Baroudjan, Barouyr, Nakouri, Ines, Renaud, Marion, Sadoux, Aurélie, Alkatrib, Marina, Deleuze, Jean-François, Battistella, Maxime, Shen, Yimin, Resche-Rigon, Matthieu, Mourah, Samia, Lebbe, Celeste, Tartour, Eric · 2025 · EMBO molecular medicine · DOI

Full title: Soluble CD27 differentially predicts resistance to anti-PD1 alone but not with anti-CTLA-4 in melanoma.

Authors: Sam, Ikuan, Benhamouda, Nadine, Biard, Lucie, Da Meda, Laetitia, Desseaux, Kristell, Baroudjan, Barouyr, Nakouri, Ines, Renaud, Marion, Sadoux, Aurélie, Alkatrib, Marina, Deleuze, Jean-François, Battistella, Maxime, Shen, Yimin, Resche-Rigon, Matthieu, Mourah, Samia, Lebbe, Celeste, Tartour, Eric

Year: 2025

Venue: EMBO molecular medicine

DOI: https://doi.org/10.1038/s44321-025-00203-9

Paper Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherapy.

Lee, Jii Bum, Kim, Hye Ryun, Ha, Sang-Jun · 2022 · Immune network · DOI

Full title: Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherapy.

Authors: Lee, Jii Bum, Kim, Hye Ryun, Ha, Sang-Jun

Year: 2022

Venue: Immune network

DOI: https://doi.org/10.4110/in.2022.22.e2

Paper [Research Progress in Immunosuppressive Tumor Microenvironment of Gastrointestinal Cancer].

Yu-ting Li, Xiangyu Tan, Liu-Na Huang, Li-xiang Ma, Li Fu · 2022 · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · DOI

Full title: [Research Progress in Immunosuppressive Tumor Microenvironment of Gastrointestinal Cancer].

Authors: Yu-ting Li, Xiangyu Tan, Liu-Na Huang, Li-xiang Ma, Li Fu

Year: 2022

Venue: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

DOI: https://doi.org/10.12182/20220160501

Paper Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Bryant, Geoffrey, Wang, Lin, Mulholland, David J. · 2017 · International Journal of Molecular Sciences · DOI

Full title: Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Authors: Bryant, Geoffrey, Wang, Lin, Mulholland, David J.

Year: 2017

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms18071542

Paper Risk of immune-related diarrhea with PD-1/PD-L1 inhibitors in different cancer types and treatment regimens.

Zhao, Lei, Yu, Jing, Wang, Jing, Li, Huihui, Che, Juanjuan, Cao, Bangwei · 2020 · Journal of Cancer · DOI

Full title: Risk of immune-related diarrhea with PD-1/PD-L1 inhibitors in different cancer types and treatment regimens.

Authors: Zhao, Lei, Yu, Jing, Wang, Jing, Li, Huihui, Che, Juanjuan, Cao, Bangwei

Year: 2020

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.32724

Paper Immunotherapy in the perioperative management of esophageal squamous cell carcinoma: recent developments.

Sun, Mengfei, Yang, Pengjie, Yang, Ting, Zhang, Jingjing, Li, Hui, Li, Yong, Zhu, Benben · 2025 · Frontiers in oncology · DOI

Full title: Immunotherapy in the perioperative management of esophageal squamous cell carcinoma: recent developments.

Authors: Sun, Mengfei, Yang, Pengjie, Yang, Ting, Zhang, Jingjing, Li, Hui, Li, Yong, Zhu, Benben

Year: 2025

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2025.1611284

Paper Combination Immunotherapy: Taking Cancer Vaccines to the Next Level

Grenier, Jeremy, Yeung, Stephen T., Khanna, Kamal M. · 2018 · Frontiers in Immunology · DOI

Full title: Combination Immunotherapy: Taking Cancer Vaccines to the Next Level

Authors: Grenier, Jeremy, Yeung, Stephen T., Khanna, Kamal M.

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.00610

Paper Advances in PD-1 and CTLA-4 dual-target immunotherapy for ovarian cancer.

Li, Dong-Mei, Pei, Kai-Ge, Yu, Xiu-Zhang, Qie, Ming-Rong, Zhong, Lan, Song, Liang · 2025 · Frontiers in immunology · DOI

Full title: Advances in PD-1 and CTLA-4 dual-target immunotherapy for ovarian cancer.

Authors: Li, Dong-Mei, Pei, Kai-Ge, Yu, Xiu-Zhang, Qie, Ming-Rong, Zhong, Lan, Song, Liang

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1686532

Paper Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs.

Maekawa, Naoya, Konnai, Satoru, Watari, Kei, Takeuchi, Hiroto, Nakanishi, Takeshi, Tachibana, Taro, Hosoya, Kenji, Kim, Sangho, Kinoshita, Ryohei, Owaki, Ryo, Yokokawa, Madoka, Kagawa, Yumiko, Takagi, Satoshi, Deguchi, Tatsuya, Ohta, Hiroshi, Kato, Yukinari, Yamamoto, Satoshi, Yamamoto, Keiichi, Suzuki, Yasuhiko, Okagawa, Tomohiro, Murata, Shiro, Ohashi, Kazuhiko · 2025 · Frontiers in immunology · DOI

Full title: Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs.

Authors: Maekawa, Naoya, Konnai, Satoru, Watari, Kei, Takeuchi, Hiroto, Nakanishi, Takeshi, Tachibana, Taro, Hosoya, Kenji, Kim, Sangho, Kinoshita, Ryohei, Owaki, Ryo, Yokokawa, Madoka, Kagawa, Yumiko, Takagi, Satoshi, Deguchi, Tatsuya, Ohta, Hiroshi, Kato, Yukinari, Yamamoto, Satoshi, Yamamoto, Keiichi, Suzuki, Yasuhiko, Okagawa, Tomohiro, Murata, Shiro, Ohashi, Kazuhiko

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1570717

Paper Comprehensive review of targeted therapy for colorectal cancer

Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan · 2020 · Signal Transduction and Targeted Therapy · DOI

Full title: Comprehensive review of targeted therapy for colorectal cancer

Authors: Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan

Year: 2020

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-020-0116-z

Paper The current status and future of targeted-immune combination for hepatocellular carcinoma.

Hao, Liyuan, Li, Shenghao, Ye, Fanghang, Wang, Hengyi, Zhong, Yuxin, Zhang, Xiaoyi, Hu, Xiaoyu, Huang, Xiaopeng · 2024 · Frontiers in immunology · DOI

Full title: The current status and future of targeted-immune combination for hepatocellular carcinoma.

Authors: Hao, Liyuan, Li, Shenghao, Ye, Fanghang, Wang, Hengyi, Zhong, Yuxin, Zhang, Xiaoyi, Hu, Xiaoyu, Huang, Xiaopeng

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1418965

Paper Oncolytic adenoviruses synergistically enhance anti-PD-L1 and anti-CTLA-4 immunotherapy by modulating the tumour microenvironment in a 4T1 orthotopic mouse model.

Zhang, Huan, Xie, Weimin, Zhang, Yuning, Dong, Xiwen, Liu, Chao, Yi, Jing, Zhang, Shun, Wen, Chunkai, Zheng, Li, Wang, Hua · 2022 · Cancer gene therapy · DOI

Full title: Oncolytic adenoviruses synergistically enhance anti-PD-L1 and anti-CTLA-4 immunotherapy by modulating the tumour microenvironment in a 4T1 orthotopic mouse model.

Authors: Zhang, Huan, Xie, Weimin, Zhang, Yuning, Dong, Xiwen, Liu, Chao, Yi, Jing, Zhang, Shun, Wen, Chunkai, Zheng, Li, Wang, Hua

Year: 2022

Venue: Cancer gene therapy

DOI: https://doi.org/10.1038/s41417-021-00389-3

Paper Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects

Wang, Siyuan, Wang, Jiaxin, Xia, Yu, Zhang, Le, Jiang, Yueqiang, Liu, Man, Gao, Qinglei, Zhang, Cuntai · 2024 · Journal of Translational Medicine · DOI

Full title: Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects

Authors: Wang, Siyuan, Wang, Jiaxin, Xia, Yu, Zhang, Le, Jiang, Yueqiang, Liu, Man, Gao, Qinglei, Zhang, Cuntai

Year: 2024

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-024-04938-w

Paper Autoimmune Polyendocrinopathy Induced by an Antibody (KN046) That Simultaneously Inhibits PD-L1 and CTLA-4: A Case Report and Literature Review.

Li, Min, Wu, Chenchen, Liu, Yan, Zhang, Ranran, Yang, Qingqing, Shi, Zhaoming, Sun, Weihua, Hu, Xiaolei · 2022 · Diabetes, metabolic syndrome and obesity : targets and therapy · DOI

Full title: Autoimmune Polyendocrinopathy Induced by an Antibody (KN046) That Simultaneously Inhibits PD-L1 and CTLA-4: A Case Report and Literature Review.

Authors: Li, Min, Wu, Chenchen, Liu, Yan, Zhang, Ranran, Yang, Qingqing, Shi, Zhaoming, Sun, Weihua, Hu, Xiaolei

Year: 2022

Venue: Diabetes, metabolic syndrome and obesity : targets and therapy

DOI: https://doi.org/10.2147/DMSO.S353403

Paper Targeting TIGIT for Immunotherapy of Cancer: Update on Clinical Development

Rotte, Anand, Sahasranaman, Srikumar, Budha, Nageshwar · 2021 · Biomedicines · DOI

Full title: Targeting TIGIT for Immunotherapy of Cancer: Update on Clinical Development

Authors: Rotte, Anand, Sahasranaman, Srikumar, Budha, Nageshwar

Year: 2021

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines9091277

Paper From Co-Stimulation to Co-Inhibition: A Continuum of Immunotherapy Care Toward Long-Term Survival in Melanoma.

Simonetti, Elena, Cutarella, Serena, Valente, Monica, Sani, Tommaso, Ravara, Matteo, Maio, Michele, Di Giacomo, Anna Maria · 2023 · OncoTargets and therapy · DOI

Full title: From Co-Stimulation to Co-Inhibition: A Continuum of Immunotherapy Care Toward Long-Term Survival in Melanoma.

Authors: Simonetti, Elena, Cutarella, Serena, Valente, Monica, Sani, Tommaso, Ravara, Matteo, Maio, Michele, Di Giacomo, Anna Maria

Year: 2023

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S368408

Paper Advances in Systemic Therapy for Hepatocellular Carcinoma and Future Prospects.

Sugimoto, Rie, Kurokawa, Miho, Tanaka, Yuki, Senju, Takeshi, Kohjima, Motoyuki, Tanaka, Masatake · 2025 · Current oncology (Toronto, Ont.) · DOI

Full title: Advances in Systemic Therapy for Hepatocellular Carcinoma and Future Prospects.

Authors: Sugimoto, Rie, Kurokawa, Miho, Tanaka, Yuki, Senju, Takeshi, Kohjima, Motoyuki, Tanaka, Masatake

Year: 2025

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol32090490

Paper Targeting TNFR2 for cancer immunotherapy: recent advances and future directions.

Li, Linxue, Ye, Ruiwei, Li, Yingying, Pan, Hanyu, Han, Sheng, Lu, Yiming · 2024 · Journal of translational medicine · DOI

Full title: Targeting TNFR2 for cancer immunotherapy: recent advances and future directions.

Authors: Li, Linxue, Ye, Ruiwei, Li, Yingying, Pan, Hanyu, Han, Sheng, Lu, Yiming

Year: 2024

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-024-05620-x

Paper Opportunistic Autoimmune Disorders Potentiated by Immune-Checkpoint Inhibitors Anti-CTLA-4 and Anti-PD-1.

Kong, Yi-Chi M, Flynn, Jeffrey C · 2014 · Frontiers in immunology · DOI

Full title: Opportunistic Autoimmune Disorders Potentiated by Immune-Checkpoint Inhibitors Anti-CTLA-4 and Anti-PD-1.

Authors: Kong, Yi-Chi M, Flynn, Jeffrey C

Year: 2014

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2014.00206

Paper CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

Quezada, Sergio A. · 2006 · Journal of Clinical Investigation · DOI

Full title: CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

Authors: Quezada, Sergio A.

Year: 2006

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci27745

Paper Immune Checkpoint Inhibitors in Malignant Melanoma: Anti-PD-1, Anti-CTLA-4 and Anti-LAG-3 Therapies.

Allen-Tejerina, Andrea M, Giannakis, Periklis, Ho Lai Yau, Thomas, Hillyar, Christopher R T, Rallis, Kathrine S · 2026 · Current oncology reports · DOI

Full title: Immune Checkpoint Inhibitors in Malignant Melanoma: Anti-PD-1, Anti-CTLA-4 and Anti-LAG-3 Therapies.

Authors: Allen-Tejerina, Andrea M, Giannakis, Periklis, Ho Lai Yau, Thomas, Hillyar, Christopher R T, Rallis, Kathrine S

Year: 2026

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-026-01750-1

Paper Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.

Singh, Manisha, Vianden, Christina, Cantwell, Mark J, Dai, Zhimin, Xiao, Zhilan, Sharma, Meenu, Khong, Hiep, Jaiswal, Ashvin R, Faak, Faisal, Hailemichael, Yared, Janssen, L M E, Bharadwaj, Uddalak, Curran, Michael A, Diab, Adi, Bassett, Roland L, Tweardy, David J, Hwu, Patrick, Overwijk, Willem W · 2017 · Nature communications · DOI

Full title: Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.

Authors: Singh, Manisha, Vianden, Christina, Cantwell, Mark J, Dai, Zhimin, Xiao, Zhilan, Sharma, Meenu, Khong, Hiep, Jaiswal, Ashvin R, Faak, Faisal, Hailemichael, Yared, Janssen, L M E, Bharadwaj, Uddalak, Curran, Michael A, Diab, Adi, Bassett, Roland L, Tweardy, David J, Hwu, Patrick, Overwijk, Willem W

Year: 2017

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-017-01572-7

Paper Prognostic and predictive value of YTHDF1 and YTHDF2 and their correlation with tumor-infiltrating immune cells in non-small cell carcinoma.

Koh, Young Wha, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo · 2022 · Frontiers in oncology · DOI

Full title: Prognostic and predictive value of YTHDF1 and YTHDF2 and their correlation with tumor-infiltrating immune cells in non-small cell carcinoma.

Authors: Koh, Young Wha, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.996634

Paper Exploring a Rarity: Incidence of and Therapeutic Approaches for Neurological Complications and Hypophysitis in Cancer Patients on Immune Checkpoint Inhibitors-A Single-Center Study.

Amylidi, Anna Lea, Gogadis, Aristeidis, Yerolatsite, Melina, Zarkavelis, George, Torounidou, Nanteznta, Keramisanou, Varvara, Kampletsas, Eleftherios, Mauri, Davide · 2023 · Current oncology (Toronto, Ont.) · DOI

Full title: Exploring a Rarity: Incidence of and Therapeutic Approaches for Neurological Complications and Hypophysitis in Cancer Patients on Immune Checkpoint Inhibitors-A Single-Center Study.

Authors: Amylidi, Anna Lea, Gogadis, Aristeidis, Yerolatsite, Melina, Zarkavelis, George, Torounidou, Nanteznta, Keramisanou, Varvara, Kampletsas, Eleftherios, Mauri, Davide

Year: 2023

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol30120766

Paper First-Line Dual Immune Checkpoint Inhibition with PD-1/PD-L1 and CTLA-4 Blockade for Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Xu, Wenqing, Niu, Chuyuan · 2026 · MEDS Clinical Medicine · DOI

Full title: First-Line Dual Immune Checkpoint Inhibition with PD-1/PD-L1 and CTLA-4 Blockade for Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Authors: Xu, Wenqing, Niu, Chuyuan

Year: 2026

Venue: MEDS Clinical Medicine

DOI: https://doi.org/10.23977/medsc.2026.070106

Paper The non-classical immune checkpoint HLA-G: a regulatory master switch governing tolerance, evasion, and translational frontiers

Huan Liu, Qiong Li, Junli Li, Ying Xue, Xiaofei Xue, Pingping Xu · 2026 · Frontiers in Oncology · DOI

Full title: The non-classical immune checkpoint HLA-G: a regulatory master switch governing tolerance, evasion, and translational frontiers

Authors: Huan Liu, Qiong Li, Junli Li, Ying Xue, Xiaofei Xue, Pingping Xu

Year: 2026

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2026.1761266

Paper Beyond monotherapy: multimodal strategies integrating immune checkpoint inhibitors in lymphoma management.

Li, Yuxiao, Zheng, Ruixin, Pan, Bing, Wang, Xiaobo, Zhang, Lina, Gao, Haiying, Li, Li · 2025 · Frontiers in immunology · DOI

Full title: Beyond monotherapy: multimodal strategies integrating immune checkpoint inhibitors in lymphoma management.

Authors: Li, Yuxiao, Zheng, Ruixin, Pan, Bing, Wang, Xiaobo, Zhang, Lina, Gao, Haiying, Li, Li

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1713199

Paper Advances in immunotherapy for thyroid malignancies: from molecular targets to clinical outcomes.

Lv, Shuo, Wang, Jinbao, Chen, Guohao, Wang, Yongshun, Liu, Naiqing · 2026 · Frontiers in medicine · DOI

Full title: Advances in immunotherapy for thyroid malignancies: from molecular targets to clinical outcomes.

Authors: Lv, Shuo, Wang, Jinbao, Chen, Guohao, Wang, Yongshun, Liu, Naiqing

Year: 2026

Venue: Frontiers in medicine

DOI: https://doi.org/10.3389/fmed.2026.1754058

Paper Characterization of a novel potency endpoint for the evaluation of immune checkpoint blockade in humanized mice.

Matas-Céspedes, Alba, Lapointe, Jean-Martin, Elder, Matthew J, Browne, Gareth J, Dovedi, Simon J, de Haan, Lolke, Maguire, Shaun, Stebbings, Richard · 2023 · Frontiers in immunology · DOI

Full title: Characterization of a novel potency endpoint for the evaluation of immune checkpoint blockade in humanized mice.

Authors: Matas-Céspedes, Alba, Lapointe, Jean-Martin, Elder, Matthew J, Browne, Gareth J, Dovedi, Simon J, de Haan, Lolke, Maguire, Shaun, Stebbings, Richard

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1107848

Paper Combining DNA damaging therapeutics with immunotherapy: more haste, less speed.

Brown, Jessica S, Sundar, Raghav, Lopez, Juanita · 2018 · British journal of cancer · DOI

Full title: Combining DNA damaging therapeutics with immunotherapy: more haste, less speed.

Authors: Brown, Jessica S, Sundar, Raghav, Lopez, Juanita

Year: 2018

Venue: British journal of cancer

DOI: https://doi.org/10.1038/bjc.2017.376

Paper Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gastric cancer in C57BL/6 J mice.

Du, Wan-Ying, Masuda, Hiroki, Nagaoka, Koji, Yasuda, Tomohiko, Kuge, Komei, Seto, Yasuyuki, Kakimi, Kazuhiro, Nomura, Sachiyo · 2024 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · DOI

Full title: Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gastric cancer in C57BL/6 J mice.

Authors: Du, Wan-Ying, Masuda, Hiroki, Nagaoka, Koji, Yasuda, Tomohiko, Kuge, Komei, Seto, Yasuyuki, Kakimi, Kazuhiro, Nomura, Sachiyo

Year: 2024

Venue: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

DOI: https://doi.org/10.1007/s10120-024-01514-5

Paper Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Li, Bo, Severson, Eric A., Pignon, Jean‐Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott J., Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley · 2016 · Genome biology · DOI

Full title: Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Authors: Li, Bo, Severson, Eric A., Pignon, Jean‐Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott J., Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley

Year: 2016

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-016-1028-7

Paper Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-negative breast cancer

Asmaa M. Zahran, Amal Rayan, Z. Zahran, Wael Mohamed, Dalia O. Mohamed, M. Abdel-Rahim, Omnia El-Badawy · 2022 · PLoS ONE · DOI

Full title: Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-negative breast cancer

Authors: Asmaa M. Zahran, Amal Rayan, Z. Zahran, Wael Mohamed, Dalia O. Mohamed, M. Abdel-Rahim, Omnia El-Badawy

Year: 2022

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0262650

Paper The efficacy and safety of immune-checkpoint inhibitors plus chemotherapy versus chemotherapy for non-small cell lung cancer: An updated systematic review and meta-analysis.

Kang, Jing, Zhang, Jun, Tian, Zongsheng, Xu, Ye, Li, Jiangbi, Li, Mingxian · 2024 · PloS one · DOI

Full title: The efficacy and safety of immune-checkpoint inhibitors plus chemotherapy versus chemotherapy for non-small cell lung cancer: An updated systematic review and meta-analysis.

Authors: Kang, Jing, Zhang, Jun, Tian, Zongsheng, Xu, Ye, Li, Jiangbi, Li, Mingxian

Year: 2024

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0276318

Paper Recent Developments of Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative Breast Cancer (TNBC)

Battogtokh, Gantumur, Obidiro, Onyinyechi, Akala, Emmanuel O. · 2024 · Preprints.org · DOI

Full title: Recent Developments of Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative Breast Cancer (TNBC)

Authors: Battogtokh, Gantumur, Obidiro, Onyinyechi, Akala, Emmanuel O.

Year: 2024

Venue: Preprints.org

DOI: https://doi.org/10.20944/preprints202404.1833.v1

Paper Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Agioti, Stephanie, Zaravinos, Apostolos · 2024 · International Journal of Molecular Sciences · DOI

Full title: Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Authors: Agioti, Stephanie, Zaravinos, Apostolos

Year: 2024

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms25073624

Paper Combined SEP and anti-PD-L1 antibody produces a synergistic antitumor effect in B16-F10 melanoma-bearing mice

Hu, Zhengping, Ye, Liang, Xing, Yingying, Hu, Jinhang, Xi, Tao · 2018 · Scientific Reports · DOI

Full title: Combined SEP and anti-PD-L1 antibody produces a synergistic antitumor effect in B16-F10 melanoma-bearing mice

Authors: Hu, Zhengping, Ye, Liang, Xing, Yingying, Hu, Jinhang, Xi, Tao

Year: 2018

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-18641-y

Paper Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.

Ruocco, Maria Grazia, Pilones, Karsten A, Kawashima, Noriko, Cammer, Michael, Huang, Julie, Babb, James S, Liu, Mengling, Formenti, Silvia C, Dustin, Michael L, Demaria, Sandra · 2012 · The Journal of clinical investigation · DOI

Full title: Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.

Authors: Ruocco, Maria Grazia, Pilones, Karsten A, Kawashima, Noriko, Cammer, Michael, Huang, Julie, Babb, James S, Liu, Mengling, Formenti, Silvia C, Dustin, Michael L, Demaria, Sandra

Year: 2012

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI61931

Paper Immune-related adverse events following administration of anti-cytotoxic T-lymphocyte-associated protein-4 drugs: a comprehensive systematic review and meta-analysis.

Xu, Hang, Tan, Ping, Zheng, Xiaonan, Huang, Yu, Lin, Tianhai, Wei, Qiang, Ai, Jianzhong, Yang, Lu · 2019 · Drug design, development and therapy · DOI

Full title: Immune-related adverse events following administration of anti-cytotoxic T-lymphocyte-associated protein-4 drugs: a comprehensive systematic review and meta-analysis.

Authors: Xu, Hang, Tan, Ping, Zheng, Xiaonan, Huang, Yu, Lin, Tianhai, Wei, Qiang, Ai, Jianzhong, Yang, Lu

Year: 2019

Venue: Drug design, development and therapy

DOI: https://doi.org/10.2147/DDDT.S196316

Paper A phase Ib study of interleukin-2 plus pembrolizumab for patients with advanced melanoma.

Silk, Ann W, Curti, Brendan, Bryan, Jennifer, Saunders, Tracie, Shih, Weichung, Kane, Michael P, Hannon, Phoebe, Fountain, Christopher, Felcher, Jessica, Zloza, Andrew, Kaufman, Howard L, Mehnert, Janice M, McDermott, David F · 2023 · Frontiers in oncology · DOI

Full title: A phase Ib study of interleukin-2 plus pembrolizumab for patients with advanced melanoma.

Authors: Silk, Ann W, Curti, Brendan, Bryan, Jennifer, Saunders, Tracie, Shih, Weichung, Kane, Michael P, Hannon, Phoebe, Fountain, Christopher, Felcher, Jessica, Zloza, Andrew, Kaufman, Howard L, Mehnert, Janice M, McDermott, David F

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1108341

Paper Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series.

Xavier, Camila B, Gouda, Mohamed A, Tsimberidou, Apostolia M · 2025 · NPJ precision oncology · DOI

Full title: Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series.

Authors: Xavier, Camila B, Gouda, Mohamed A, Tsimberidou, Apostolia M

Year: 2025

Venue: NPJ precision oncology

DOI: https://doi.org/10.1038/s41698-025-01115-0

Paper Clinical Insights Into Novel Immune Checkpoint Inhibitors.

Lee, Jii Bum, Ha, Sang-Jun, Kim, Hye Ryun · 2021 · Frontiers in pharmacology · DOI

Full title: Clinical Insights Into Novel Immune Checkpoint Inhibitors.

Authors: Lee, Jii Bum, Ha, Sang-Jun, Kim, Hye Ryun

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.681320

Paper Immune checkpoint inhibition perturbs neuro-immune homeostasis and impairs cognitive function.

Ifejeokwu, Onwodi V, Do, An H, El Khatib, Sanad M, Ho, Nhu N, Zavala, Angel, Othy, Shivashankar, Acharya, Munjal M · 2025 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Immune checkpoint inhibition perturbs neuro-immune homeostasis and impairs cognitive function.

Authors: Ifejeokwu, Onwodi V, Do, An H, El Khatib, Sanad M, Ho, Nhu N, Zavala, Angel, Othy, Shivashankar, Acharya, Munjal M

Year: 2025

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-025-03442-3

Paper Novel approaches for the treatment of unresectable malignant pleural mesothelioma: A focus on immunotherapy and target therapy (Review)

Rijavec, Erika, Biello, Federica, Barletta, Giulia, Dellepiane, Chiara, Genova, Carlo · 2022 · Molecular and Clinical Oncology · DOI

Full title: Novel approaches for the treatment of unresectable malignant pleural mesothelioma: A focus on immunotherapy and target therapy (Review)

Authors: Rijavec, Erika, Biello, Federica, Barletta, Giulia, Dellepiane, Chiara, Genova, Carlo

Year: 2022

Venue: Molecular and Clinical Oncology

DOI: https://doi.org/10.3892/mco.2022.2522

Paper Immune Microenvironment in Osteosarcoma: Components, Therapeutic Strategies and Clinical Applications

Zhu, Tianyi, Han, Jing, Liu, Yang, Cai, Zhengdong, Sun, Wei, Hua, Yingqi, Xu, Jing · 2022 · Frontiers in Immunology · DOI

Full title: Immune Microenvironment in Osteosarcoma: Components, Therapeutic Strategies and Clinical Applications

Authors: Zhu, Tianyi, Han, Jing, Liu, Yang, Cai, Zhengdong, Sun, Wei, Hua, Yingqi, Xu, Jing

Year: 2022

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2022.907550

Paper Spotlight on nivolumab in the treatment of renal cell carcinoma: design, development, and place in therapy.

Venur, Vyshak Alva, Joshi, Monika, Nepple, Kenneth G, Zakharia, Yousef · 2017 · Drug design, development and therapy · DOI

Full title: Spotlight on nivolumab in the treatment of renal cell carcinoma: design, development, and place in therapy.

Authors: Venur, Vyshak Alva, Joshi, Monika, Nepple, Kenneth G, Zakharia, Yousef

Year: 2017

Venue: Drug design, development and therapy

DOI: https://doi.org/10.2147/DDDT.S110209

Paper Cytoreductive Nephrectomy After Combination of Nivolumab Plus Ipilimumab for Mucinous Tubular and Spindle Cell Carcinoma of the Kidney With Bone Metastases: A Case Report

Nobuki Furubayashi, K. Taguchi, T. Negishi, A. Miura, Y. Sato, M. Miyoshi, Motonobu Nakamura · 2021 · In Vivo · DOI

Full title: Cytoreductive Nephrectomy After Combination of Nivolumab Plus Ipilimumab for Mucinous Tubular and Spindle Cell Carcinoma of the Kidney With Bone Metastases: A Case Report

Authors: Nobuki Furubayashi, K. Taguchi, T. Negishi, A. Miura, Y. Sato, M. Miyoshi, Motonobu Nakamura

Year: 2021

Venue: In Vivo

DOI: https://doi.org/10.21873/invivo.12732

Paper Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer.

Yang, Xueli, Wei, Wujun, Feng, Zhihui, Zhang, Biao, Liu, Yi, Yang, Fei, Zhang, Chong, Ou, Minglin, Liao, Songbai, Hou, Xianliang · 2026 · Oncology letters · DOI

Full title: Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer.

Authors: Yang, Xueli, Wei, Wujun, Feng, Zhihui, Zhang, Biao, Liu, Yi, Yang, Fei, Zhang, Chong, Ou, Minglin, Liao, Songbai, Hou, Xianliang

Year: 2026

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2025.15420

Paper Current Knowledge and Perspectives of Immunotherapies for Neuroblastoma.

Mao, Chenkai, Poimenidou, Maria, Craig, Brian T · 2024 · Cancers · DOI

Full title: Current Knowledge and Perspectives of Immunotherapies for Neuroblastoma.

Authors: Mao, Chenkai, Poimenidou, Maria, Craig, Brian T

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16162865

Paper Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ Toxicity After a Single Dose of CTLA-4 Plus PD-1 Blockade: A Case Report.

Matull, Johanna, Livingstone, Elisabeth, Wetter, Axel, Zimmer, Lisa, Zaremba, Anne, Lahner, Harald, Schadendorf, Dirk, Ugurel, Selma · 2020 · Frontiers in oncology · DOI

Full title: Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ Toxicity After a Single Dose of CTLA-4 Plus PD-1 Blockade: A Case Report.

Authors: Matull, Johanna, Livingstone, Elisabeth, Wetter, Axel, Zimmer, Lisa, Zaremba, Anne, Lahner, Harald, Schadendorf, Dirk, Ugurel, Selma

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.592609

Paper Current Approaches to Neoadjuvant Immunotherapy in Resectable Non-small Cell Lung Cancer

Parekh, Jay, Parikh, Kaushal, Reuss, Joshua E., Friedlaender, Alex, Addeo, Alfredo · 2023 · Current Oncology Reports · DOI

Full title: Current Approaches to Neoadjuvant Immunotherapy in Resectable Non-small Cell Lung Cancer

Authors: Parekh, Jay, Parikh, Kaushal, Reuss, Joshua E., Friedlaender, Alex, Addeo, Alfredo

Year: 2023

Venue: Current Oncology Reports

DOI: https://doi.org/10.1007/s11912-023-01430-4

Paper Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.

Seidel, Judith A, Otsuka, Atsushi, Kabashima, Kenji · 2018 · Frontiers in oncology · DOI

Full title: Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.

Authors: Seidel, Judith A, Otsuka, Atsushi, Kabashima, Kenji

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00086

Paper Pretreatment naive T cells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma.

Marks, Kathryne E, Horisberger, Alice, Elahee, Mehreen, Adejoorin, Ifeoluwakiisi A, Ghosh, Nilasha, Postow, Michael, Donlin, Laura, Bass, Anne R, Rao, Deepak A · 2026 · JCI insight · DOI

Full title: Pretreatment naive T cells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma.

Authors: Marks, Kathryne E, Horisberger, Alice, Elahee, Mehreen, Adejoorin, Ifeoluwakiisi A, Ghosh, Nilasha, Postow, Michael, Donlin, Laura, Bass, Anne R, Rao, Deepak A

Year: 2026

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.198203

Paper The Uncharted Landscape of Rare Endocrine Immune-Related Adverse Events.

Mytareli, Chrysoula, Ziogas, Dimitrios C, Karampela, Athina, Papalexis, Petros, Siampanopoulou, Vasiliki, Lafioniatis, Alexandros, Benopoulou, Olga, Gogas, Helen, Angelousi, Anna · 2023 · Cancers · DOI

Full title: The Uncharted Landscape of Rare Endocrine Immune-Related Adverse Events.

Authors: Mytareli, Chrysoula, Ziogas, Dimitrios C, Karampela, Athina, Papalexis, Petros, Siampanopoulou, Vasiliki, Lafioniatis, Alexandros, Benopoulou, Olga, Gogas, Helen, Angelousi, Anna

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15072016

Paper Impaired Heat Shock Protein Expression in Activated T Cells in B-Cell Lymphoma.

Albakova, Zarema, Mangasarova, Yana, Sapozhnikov, Alexander · 2022 · Biomedicines · DOI

Full title: Impaired Heat Shock Protein Expression in Activated T Cells in B-Cell Lymphoma.

Authors: Albakova, Zarema, Mangasarova, Yana, Sapozhnikov, Alexander

Year: 2022

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines10112747

Paper Efficacy and safety of cadonilimab (PD-1/CTLA-4 bispecific) in combination with chemotherapy in anti-PD-1-resistant recurrent or metastatic nasopharyngeal carcinoma: a single-arm, open-label, phase 2 trial.

Jiang, Yaofei, Bei, Weixin, Wang, Lin, Lu, Nian, Xu, Cheng, Liang, Hu, Ke, Liangru, Ye, Yanfang, He, Shuiqing, Dong, Shuhui, Liu, Qin, Zhang, Chuanrun, Wang, Xuguang, Xia, Weixiong, Zhao, Chong, Huang, Ying, Xiang, Yanqun, Liu, Guoying · 2025 · BMC medicine · DOI

Full title: Efficacy and safety of cadonilimab (PD-1/CTLA-4 bispecific) in combination with chemotherapy in anti-PD-1-resistant recurrent or metastatic nasopharyngeal carcinoma: a single-arm, open-label, phase 2 trial.

Authors: Jiang, Yaofei, Bei, Weixin, Wang, Lin, Lu, Nian, Xu, Cheng, Liang, Hu, Ke, Liangru, Ye, Yanfang, He, Shuiqing, Dong, Shuhui, Liu, Qin, Zhang, Chuanrun, Wang, Xuguang, Xia, Weixiong, Zhao, Chong, Huang, Ying, Xiang, Yanqun, Liu, Guoying

Year: 2025

Venue: BMC medicine

DOI: https://doi.org/10.1186/s12916-025-03985-4

Paper PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism.

Dong, Hao, Qi, Yihang, Kong, Xiangyi, Wang, Zhongzhao, Fang, Yi, Wang, Jing · 2022 · Frontiers in pharmacology · DOI

Full title: PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism.

Authors: Dong, Hao, Qi, Yihang, Kong, Xiangyi, Wang, Zhongzhao, Fang, Yi, Wang, Jing

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.835510

Paper The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma

Fan, Mengke, Qi, Lili, Zhang, Qi, Wang, Ling · 2021 · Cancer Management and Research · DOI

Full title: The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma

Authors: Fan, Mengke, Qi, Lili, Zhang, Qi, Wang, Ling

Year: 2021

Venue: Cancer Management and Research

DOI: https://doi.org/10.2147/cmar.s285560

Paper 225Actinium-armed antibody targeting CCR8+ regulatory T cells synergizes with immunotherapy to promote tumor rejection in syngeneic colorectal cancer models.

Frank, Connor, Xiao, Zhiwen, Allen, Kevin J H, Jiao, Rubin, Malo, Mackenzie E, Dadachova, Ekaterina · 2025 · Frontiers in immunology · DOI

Full title: 225Actinium-armed antibody targeting CCR8+ regulatory T cells synergizes with immunotherapy to promote tumor rejection in syngeneic colorectal cancer models.

Authors: Frank, Connor, Xiao, Zhiwen, Allen, Kevin J H, Jiao, Rubin, Malo, Mackenzie E, Dadachova, Ekaterina

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1662216

Paper Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers

Heiniö, Camilla, Clubb, James H.A., Kudling, Tatiana V., Quixabeira, Dafne C.A., Cervera-Carrascón, Víctor, Havunen, Riikka, Grönberg-Vähä-Koskela, Susanna, Santos, João M., Tapper, Johanna, Kanerva, Anna, Hemminki, Akseli · 2022 · Diseases · DOI

Full title: Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers

Authors: Heiniö, Camilla, Clubb, James H.A., Kudling, Tatiana V., Quixabeira, Dafne C.A., Cervera-Carrascón, Víctor, Havunen, Riikka, Grönberg-Vähä-Koskela, Susanna, Santos, João M., Tapper, Johanna, Kanerva, Anna, Hemminki, Akseli

Year: 2022

Venue: Diseases

DOI: https://doi.org/10.3390/diseases10030052

Paper Nivolumab in the treatment of thoracic cancer — new possibilities

Knetki‐Wróblewska, Magdalena, Wojas‐Krawczyk, Kamila · 2022 · Oncology in Clinical Practice · DOI

Full title: Nivolumab in the treatment of thoracic cancer — new possibilities

Authors: Knetki‐Wróblewska, Magdalena, Wojas‐Krawczyk, Kamila

Year: 2022

Venue: Oncology in Clinical Practice

DOI: https://doi.org/10.5603/ocp.2022.0033

Paper Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.

Kirchberger, Michael Constantin, Moreira, Alvaro, Erdmann, Michael, Schuler, Gerold, Heinzerling, Lucie · 2018 · Oncotarget · DOI

Full title: Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.

Authors: Kirchberger, Michael Constantin, Moreira, Alvaro, Erdmann, Michael, Schuler, Gerold, Heinzerling, Lucie

Year: 2018

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.25627

Paper Radiation and Immune Checkpoint Inhibitors: Combination Therapy for Treatment of Hepatocellular Carcinoma.

Chami, Perla, Diab, Youssef, Khalil, Danny N, Azhari, Hassan, Jarnagin, William R, Abou-Alfa, Ghassan K, Harding, James J, Hajj, Joseph, Ma, Jennifer, El Homsi, Maria, Reyngold, Marsha, Crane, Christopher, Hajj, Carla · 2023 · International journal of molecular sciences · DOI

Full title: Radiation and Immune Checkpoint Inhibitors: Combination Therapy for Treatment of Hepatocellular Carcinoma.

Authors: Chami, Perla, Diab, Youssef, Khalil, Danny N, Azhari, Hassan, Jarnagin, William R, Abou-Alfa, Ghassan K, Harding, James J, Hajj, Joseph, Ma, Jennifer, El Homsi, Maria, Reyngold, Marsha, Crane, Christopher, Hajj, Carla

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms242316773

Paper Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors

Yang, Ximing, Gao, Miaozhi, Xu, Runshi, Tao, Yangyang, Wang, Luo, Wang, Binya, Zhong, Wenliang, He, Lan, He, Yingchun · 2022 · Frontiers in Immunology · DOI

Full title: Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors

Authors: Yang, Ximing, Gao, Miaozhi, Xu, Runshi, Tao, Yangyang, Wang, Luo, Wang, Binya, Zhong, Wenliang, He, Lan, He, Yingchun

Year: 2022

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2022.969447

Paper Molecular and Genetic Immune Biomarkers of Primary and Immune-Therapy Induced Hypophysitis: From Laboratories to the Clinical Practice.

Chiloiro, Sabrina, Russo, Filippo, Tartaglione, Tommaso, Capoluongo, Ettore Domenico · 2021 · Journal of personalized medicine · DOI

Full title: Molecular and Genetic Immune Biomarkers of Primary and Immune-Therapy Induced Hypophysitis: From Laboratories to the Clinical Practice.

Authors: Chiloiro, Sabrina, Russo, Filippo, Tartaglione, Tommaso, Capoluongo, Ettore Domenico

Year: 2021

Venue: Journal of personalized medicine

DOI: https://doi.org/10.3390/jpm11101026

Paper Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.

Said, Sawsan Sudqi, Ibrahim, Wisam Nabeel · 2024 · Biomedicines · DOI

Full title: Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.

Authors: Said, Sawsan Sudqi, Ibrahim, Wisam Nabeel

Year: 2024

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines12020369

Paper New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Hirsh, Vera · 2017 · OncoTargets and Therapy · DOI

Full title: New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Authors: Hirsh, Vera

Year: 2017

Venue: OncoTargets and Therapy

DOI: https://doi.org/10.2147/ott.s104177

Paper Data Sheet 1_Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.docx

(10068460), Xinyao Wang, (11716952), Yuli Zhang, (16543), Wei Xie, (135547), Haiying Liu, (22589156), Lianghui Cui, (141118), Min Feng · 2025 · Figshare · DOI

Full title: Data Sheet 1_Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.docx

Authors: (10068460), Xinyao Wang, (11716952), Yuli Zhang, (16543), Wei Xie, (135547), Haiying Liu, (22589156), Lianghui Cui, (141118), Min Feng

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.3389/fonc.2025.1659897.s001

Paper Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy.

Ren, Xiufang, Guo, Songyi, Guan, Xiaojiao, Kang, Ye, Liu, Jiamei, Yang, Xianghong · 2022 · Frontiers in immunology · DOI

Full title: Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy.

Authors: Ren, Xiufang, Guo, Songyi, Guan, Xiaojiao, Kang, Ye, Liu, Jiamei, Yang, Xianghong

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.790113

Paper Immunomodulatory Properties of Immune Checkpoint Inhibitors-More than Boosting T-Cell Responses?

Kuske, Michael, Haist, Maximilian, Jung, Thomas, Grabbe, Stephan, Bros, Matthias · 2022 · Cancers · DOI

Full title: Immunomodulatory Properties of Immune Checkpoint Inhibitors-More than Boosting T-Cell Responses?

Authors: Kuske, Michael, Haist, Maximilian, Jung, Thomas, Grabbe, Stephan, Bros, Matthias

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14071710

Paper Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.

Pourmir, Ivan, Benhamouda, Nadine, Tran, Thi, Roux, Hugo, Pineau, Joséphine, Gey, Alain, Munoz, Andyara, Mabrouk, Nesrine, Epaillard, Nicolas, Verkarre, Virginie, Vano, Yann-Alexandre, Tartour, Eric, Oudard, Stéphane · 2025 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.

Authors: Pourmir, Ivan, Benhamouda, Nadine, Tran, Thi, Roux, Hugo, Pineau, Joséphine, Gey, Alain, Munoz, Andyara, Mabrouk, Nesrine, Epaillard, Nicolas, Verkarre, Virginie, Vano, Yann-Alexandre, Tartour, Eric, Oudard, Stéphane

Year: 2025

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-025-03293-y

Paper Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.

Liu, Maobai, Cheng, Xitong, Ni, Ruping, Zheng, Bin, Huang, Shunmin, Yang, Jing · 2022 · Frontiers in immunology · DOI

Full title: Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.

Authors: Liu, Maobai, Cheng, Xitong, Ni, Ruping, Zheng, Bin, Huang, Shunmin, Yang, Jing

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.1006860

Paper Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).

Genoud, Vassilis, Espinoza, Felipe I, Marinari, Eliana, Rochemont, Viviane, Dietrich, Pierre-Yves, McSheehy, Paul, Bachmann, Felix, Lane, Heidi A, Walker, Paul R · 2021 · JCI insight · DOI

Full title: Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).

Authors: Genoud, Vassilis, Espinoza, Felipe I, Marinari, Eliana, Rochemont, Viviane, Dietrich, Pierre-Yves, McSheehy, Paul, Bachmann, Felix, Lane, Heidi A, Walker, Paul R

Year: 2021

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.142980

Paper It might be a dead end: immune checkpoint inhibitor therapy in EGFR-mutated NSCLC.

Akao, Ken, Oya, Yuko, Sato, Takaya, Ikeda, Aki, Horiguchi, Tomoya, Goto, Yasuhiro, Hashimoto, Naozumi, Kondo, Masashi, Imaizumi, Kazuyoshi · 2024 · Exploration of targeted anti-tumor therapy · DOI

Full title: It might be a dead end: immune checkpoint inhibitor therapy in EGFR-mutated NSCLC.

Authors: Akao, Ken, Oya, Yuko, Sato, Takaya, Ikeda, Aki, Horiguchi, Tomoya, Goto, Yasuhiro, Hashimoto, Naozumi, Kondo, Masashi, Imaizumi, Kazuyoshi

Year: 2024

Venue: Exploration of targeted anti-tumor therapy

DOI: https://doi.org/10.37349/etat.2024.00251

Paper Stoking an anti-liver cancer immune response with cryoablation plus an intratumoral TLR9 agonist and dual checkpoint inhibitors.

Yang, Yunpeng, Mandt, Tyler, Mittelstein, David, Das, Manasi, Wu, Panyisha, Ghani, Mansur A, Illindala, Ritvik, Steinmetz, Nicole F, Burgoyne, Adam M, Berman, Zachary, Webster, Nicholas, Newton, Isabel G · 2026 · Cancer immunology, immunotherapy : CII · DOI

Full title: Stoking an anti-liver cancer immune response with cryoablation plus an intratumoral TLR9 agonist and dual checkpoint inhibitors.

Authors: Yang, Yunpeng, Mandt, Tyler, Mittelstein, David, Das, Manasi, Wu, Panyisha, Ghani, Mansur A, Illindala, Ritvik, Steinmetz, Nicole F, Burgoyne, Adam M, Berman, Zachary, Webster, Nicholas, Newton, Isabel G

Year: 2026

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-025-04286-8

Paper Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma.

Tucker, Matthew D, Rini, Brian I · 2020 · Cancers · DOI

Full title: Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma.

Authors: Tucker, Matthew D, Rini, Brian I

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12092662

Paper Efficacy and Safety of Programmed Death-1/Programmed Death-Ligand 1 Inhibitor for Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis.

Liao, Pei-Fei, Wang, Ping-Yu, Peng, Tzu-Rong · 2023 · Current oncology (Toronto, Ont.) · DOI

Full title: Efficacy and Safety of Programmed Death-1/Programmed Death-Ligand 1 Inhibitor for Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis.

Authors: Liao, Pei-Fei, Wang, Ping-Yu, Peng, Tzu-Rong

Year: 2023

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol30110722

Paper The role of immune checkpoints in cardiovascular disease.

Yousif, Laura I, Tanja, Anniek A, de Boer, Rudolf A, Teske, Arco J, Meijers, Wouter C · 2022 · Frontiers in pharmacology · DOI

Full title: The role of immune checkpoints in cardiovascular disease.

Authors: Yousif, Laura I, Tanja, Anniek A, de Boer, Rudolf A, Teske, Arco J, Meijers, Wouter C

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.989431

Paper Metabolism and senescence in the immune microenvironment of osteosarcoma: focus on new therapeutic strategies

Ying, Hui, Li, Zhiqiang, Li, Meng-Pan, Liu, Wencai · 2023 · Frontiers in Endocrinology · DOI

Full title: Metabolism and senescence in the immune microenvironment of osteosarcoma: focus on new therapeutic strategies

Authors: Ying, Hui, Li, Zhiqiang, Li, Meng-Pan, Liu, Wencai

Year: 2023

Venue: Frontiers in Endocrinology

DOI: https://doi.org/10.3389/fendo.2023.1217669

Paper Immune Checkpoint Inhibitors' Associated Renal Toxicity: A Series of 12 Cases.

Palamaris, Kostas, Alexandris, Dimitrios, Stylianou, Kostas, Giatras, Ioannis, Stofas, Anastasios, Kaitatzoglou, Christina, Migkou, Magda, Goutas, Dimitrios, Psimenou, Erasmia, Theodoropoulou, Eleni, Theocharis, Stamatios, Alevizopoulos, Nektarios, Kastritis, Efstathios, Gerakis, Alexandros, Gakiopoulou, Harikleia · 2022 · Journal of clinical medicine · DOI

Full title: Immune Checkpoint Inhibitors' Associated Renal Toxicity: A Series of 12 Cases.

Authors: Palamaris, Kostas, Alexandris, Dimitrios, Stylianou, Kostas, Giatras, Ioannis, Stofas, Anastasios, Kaitatzoglou, Christina, Migkou, Magda, Goutas, Dimitrios, Psimenou, Erasmia, Theodoropoulou, Eleni, Theocharis, Stamatios, Alevizopoulos, Nektarios, Kastritis, Efstathios, Gerakis, Alexandros, Gakiopoulou, Harikleia

Year: 2022

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm11164786

Paper ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

Wu, Youqian, Zhang, Chao, Liu, Xiaolan, He, Zhengfu, Shan, Bing, Zeng, Qingxin, Zhao, Qingwei, Zhu, Huaying, Liao, Hongwei, Cen, Xufeng, Xu, Xiaoyan, Zhang, Mengmeng, Hou, Tingjun, Wang, Zhe, Yan, Huanhuan, Yang, Shuying, Sun, Yaqin, Chen, Yanying, Wu, Ronghai, Xie, Tingxue, Chen, Wei, Najafov, Ayaz, Ying, Songmin, Xia, Hongguang · 2021 · Nature communications · DOI

Full title: ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

Authors: Wu, Youqian, Zhang, Chao, Liu, Xiaolan, He, Zhengfu, Shan, Bing, Zeng, Qingxin, Zhao, Qingwei, Zhu, Huaying, Liao, Hongwei, Cen, Xufeng, Xu, Xiaoyan, Zhang, Mengmeng, Hou, Tingjun, Wang, Zhe, Yan, Huanhuan, Yang, Shuying, Sun, Yaqin, Chen, Yanying, Wu, Ronghai, Xie, Tingxue, Chen, Wei, Najafov, Ayaz, Ying, Songmin, Xia, Hongguang

Year: 2021

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-021-22467-8

Paper TGFβ2 Induces the Soluble Isoform of CTLA-4 - Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma.

Khanolkar, Rahul C, Zhang, Chu, Al-Fatyan, Farah, Lawson, Linda, Depasquale, Ivan, Meredith, Fiona M, Muller, Frank, Nicolson, Marianne, Dahal, Lekh Nath, Abu-Eid, Rasha, Rajpara, Sanjay, Barker, Robert Norman, Ormerod, Anthony D, Ward, Frank James · 2021 · Frontiers in immunology · DOI

Full title: TGFβ2 Induces the Soluble Isoform of CTLA-4 - Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma.

Authors: Khanolkar, Rahul C, Zhang, Chu, Al-Fatyan, Farah, Lawson, Linda, Depasquale, Ivan, Meredith, Fiona M, Muller, Frank, Nicolson, Marianne, Dahal, Lekh Nath, Abu-Eid, Rasha, Rajpara, Sanjay, Barker, Robert Norman, Ormerod, Anthony D, Ward, Frank James

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.763877

Paper Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.

Wang, Li, Li, Xiaolin, Zhao, Bin, Mei, Dan, Jiang, Jiandong, Duan, Jingli · 2021 · Frontiers in pharmacology · DOI

Full title: Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.

Authors: Wang, Li, Li, Xiaolin, Zhao, Bin, Mei, Dan, Jiang, Jiandong, Duan, Jingli

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.679207

Paper Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoint blockade

Weihong Tian, Gaofeng Qin, Miaomiao Jia, Wuhao Li, Weili Cai, Hui Wang, Yangjing Zhao, Xuanwen Bao, Wangzhi Wei, Yu Zhang, Qixiang Shao · 2023 · Frontiers in Immunology · DOI

Full title: Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoint blockade

Authors: Weihong Tian, Gaofeng Qin, Miaomiao Jia, Wuhao Li, Weili Cai, Hui Wang, Yangjing Zhao, Xuanwen Bao, Wangzhi Wei, Yu Zhang, Qixiang Shao

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1198551

Paper Immune checkpoint inhibitors in metastatic melanoma therapy (Review).

Shah, Vedant, Panchal, Viraj, Shah, Abhi, Vyas, Bhavya, Agrawal, Siddharth, Bharadwaj, Sanket · 2024 · Medicine international · DOI

Full title: Immune checkpoint inhibitors in metastatic melanoma therapy (Review).

Authors: Shah, Vedant, Panchal, Viraj, Shah, Abhi, Vyas, Bhavya, Agrawal, Siddharth, Bharadwaj, Sanket

Year: 2024

Venue: Medicine international

DOI: https://doi.org/10.3892/mi.2024.137

Paper Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors.

Xavier, Camila B, Lopes, Carlos Diego H, Awni, Beatriz M, Campos, Eduardo F, Alves, João Pedro B, Camargo, Anamaria A, Guardia, Gabriela D A, Galante, Pedro A F, Jardim, Denis L · 2022 · Cancers · DOI

Full title: Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors.

Authors: Xavier, Camila B, Lopes, Carlos Diego H, Awni, Beatriz M, Campos, Eduardo F, Alves, João Pedro B, Camargo, Anamaria A, Guardia, Gabriela D A, Galante, Pedro A F, Jardim, Denis L

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14215433

Paper From cold to hot tumors: feasibility of applying therapeutic insights to TNBC.

Yan, Shaozhang, Sun, Xinyue, Wang, Kuanyu · 2025 · Discover oncology · DOI

Full title: From cold to hot tumors: feasibility of applying therapeutic insights to TNBC.

Authors: Yan, Shaozhang, Sun, Xinyue, Wang, Kuanyu

Year: 2025

Venue: Discover oncology

DOI: https://doi.org/10.1007/s12672-025-03745-z

Paper Case Report: Dual checkpoint inhibition with bevacizumab yields dramatic response in synchronous double primary HCC and ICC with lung metastasis.

He, Yu-Cheng, Dai, Xin-Ye, Lv, Ying-Hao, Yang, Xiao-Juan, Xie, Qing-Yun, Xie, Si-Nan, Cai, Yun-Shi, Gao, Feng-Wei, Lan, Tian · 2025 · Frontiers in oncology · DOI

Full title: Case Report: Dual checkpoint inhibition with bevacizumab yields dramatic response in synchronous double primary HCC and ICC with lung metastasis.

Authors: He, Yu-Cheng, Dai, Xin-Ye, Lv, Ying-Hao, Yang, Xiao-Juan, Xie, Qing-Yun, Xie, Si-Nan, Cai, Yun-Shi, Gao, Feng-Wei, Lan, Tian

Year: 2025

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2025.1670818

Paper Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.

Peer, Sebastian, Baier, Gottfried, Gruber, Thomas · 2017 · Oncotarget · DOI

Full title: Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.

Authors: Peer, Sebastian, Baier, Gottfried, Gruber, Thomas

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.18360

Paper Rationale of Immunotherapy in Hepatocellular Carcinoma and Its Potential Biomarkers.

Tai, David, Choo, Su Pin, Chew, Valerie · 2019 · Cancers · DOI

Full title: Rationale of Immunotherapy in Hepatocellular Carcinoma and Its Potential Biomarkers.

Authors: Tai, David, Choo, Su Pin, Chew, Valerie

Year: 2019

Venue: Cancers

DOI: https://doi.org/10.3390/cancers11121926

Paper Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors.

Lin, Anqi, Huang, Lihaoyun, Jiang, Aimin, Zhu, Lingxuan, Mou, Weiming, Li, Yu, Zhang, Chunyan, Liu, Zaoqu, Zhang, Jian, Cheng, Quan, Wei, Ting, Luo, Peng · 2025 · BMC medicine · DOI

Full title: Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors.

Authors: Lin, Anqi, Huang, Lihaoyun, Jiang, Aimin, Zhu, Lingxuan, Mou, Weiming, Li, Yu, Zhang, Chunyan, Liu, Zaoqu, Zhang, Jian, Cheng, Quan, Wei, Ting, Luo, Peng

Year: 2025

Venue: BMC medicine

DOI: https://doi.org/10.1186/s12916-025-04183-y

Paper Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Garman, Bradley, Jiang, Can, Daouti, Sherif, Kumar, Sanah, Mehta, Priyanka, Jacques, Miye K., Ménard, Laurence, Manjarrez‐Orduño, Nataly, Dolfi, Sonia, Mukherjee, Piali, Chamling, Sharmila, Lako, Ana, Koenitzer, Jennifer, David, Justin M. · 2023 · Frontiers in Immunology · DOI

Full title: Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Authors: Garman, Bradley, Jiang, Can, Daouti, Sherif, Kumar, Sanah, Mehta, Priyanka, Jacques, Miye K., Ménard, Laurence, Manjarrez‐Orduño, Nataly, Dolfi, Sonia, Mukherjee, Piali, Chamling, Sharmila, Lako, Ana, Koenitzer, Jennifer, David, Justin M.

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1151748

Paper Severe cardiac events induced by combination immunotherapy in patients with cancer: a meta-analysis.

Valenzuela-Rodriguez, German, Diaz-Arocutipa, Carlos, Collins, Jaime A, Lopez-Fernandez, Teresa, Gomez, Henry L, Hernandez, Adrian V · 2023 · Archives of medical science : AMS · DOI

Full title: Severe cardiac events induced by combination immunotherapy in patients with cancer: a meta-analysis.

Authors: Valenzuela-Rodriguez, German, Diaz-Arocutipa, Carlos, Collins, Jaime A, Lopez-Fernandez, Teresa, Gomez, Henry L, Hernandez, Adrian V

Year: 2023

Venue: Archives of medical science : AMS

DOI: https://doi.org/10.5114/aoms/168124

Paper Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patients with advanced intrahepatic cholangiocarcinoma.

Huang, Jia-Xin, Liu, Bo, Li, Yu, Li, Xi, Ding, Li-Juan, Wang, Nan-Ya · 2023 · Frontiers in oncology · DOI

Full title: Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patients with advanced intrahepatic cholangiocarcinoma.

Authors: Huang, Jia-Xin, Liu, Bo, Li, Yu, Li, Xi, Ding, Li-Juan, Wang, Nan-Ya

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1204486

Paper Decision-Making Biomarkers Guiding Therapeutic Strategies in Hepatocellular Carcinoma: From Prediction to Personalized Care.

Liu, Dongming, Imai, Norihiro · 2025 · Cancers · DOI

Full title: Decision-Making Biomarkers Guiding Therapeutic Strategies in Hepatocellular Carcinoma: From Prediction to Personalized Care.

Authors: Liu, Dongming, Imai, Norihiro

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17193105

Paper Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient.

Zhang, Er-Lei, Zhang, Zun-Yi, Li, Jian, Huang, Zhi-Yong · 2020 · OncoTargets and therapy · DOI

Full title: Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient.

Authors: Zhang, Er-Lei, Zhang, Zun-Yi, Li, Jian, Huang, Zhi-Yong

Year: 2020

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S284092

Paper Efficacy and Safety of PD-1/PD-L1 Inhibitors in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis

Zhen-Yu Li, Zhen Zhang, Xiaozhong Cao, Yun Feng, Shasha Ren · 2023 · Clinical and Experimental Obstetrics & Gynecology · DOI

Full title: Efficacy and Safety of PD-1/PD-L1 Inhibitors in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis

Authors: Zhen-Yu Li, Zhen Zhang, Xiaozhong Cao, Yun Feng, Shasha Ren

Year: 2023

Venue: Clinical and Experimental Obstetrics & Gynecology

DOI: https://doi.org/10.31083/j.ceog5009185

Paper Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies.

Kato, Daiki, Yaguchi, Tomonori, Iwata, Takashi, Morii, Kenji, Nakagawa, Takayuki, Nishimura, Ryohei, Kawakami, Yutaka · 2017 · Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology · DOI

Full title: Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies.

Authors: Kato, Daiki, Yaguchi, Tomonori, Iwata, Takashi, Morii, Kenji, Nakagawa, Takayuki, Nishimura, Ryohei, Kawakami, Yutaka

Year: 2017

Venue: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

DOI: https://doi.org/10.2177/jsci.40.68

Paper Review of Current and Future Medical Treatments in Head and Neck Squamous Cell Carcinoma

Lee, Aaron M., Weaver, Alice N., Acosta, Phillip, Harris, Lauren, Bowles, Daniel W. · 2024 · Cancers · DOI

Full title: Review of Current and Future Medical Treatments in Head and Neck Squamous Cell Carcinoma

Authors: Lee, Aaron M., Weaver, Alice N., Acosta, Phillip, Harris, Lauren, Bowles, Daniel W.

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16203488

Paper Recent advances in Merkel cell carcinoma.

Robinson, Caitlin G, Tan, Daniel, Yu, Siegrid S · 2019 · F1000Research · DOI

Full title: Recent advances in Merkel cell carcinoma.

Authors: Robinson, Caitlin G, Tan, Daniel, Yu, Siegrid S

Year: 2019

Venue: F1000Research

DOI: https://doi.org/10.12688/f1000research.20747.1

Paper The advances in immunotherapy for hepatocellular carcinoma

Zhang, Fan, Li, Yumin · 2020 · Hepatoma Research · DOI

Full title: The advances in immunotherapy for hepatocellular carcinoma

Authors: Zhang, Fan, Li, Yumin

Year: 2020

Venue: Hepatoma Research

DOI: https://doi.org/10.20517/2394-5079.2020.20

Paper Severe Late-Onset Grade III-IV Adverse Events under Immunotherapy: A Retrospective Study of 79 Cases.

L'Orphelin, Jean-Matthieu, Varey, Emilie, Khammari, Amir, Dreno, Brigitte, Dompmartin, Anne · 2021 · Cancers · DOI

Full title: Severe Late-Onset Grade III-IV Adverse Events under Immunotherapy: A Retrospective Study of 79 Cases.

Authors: L'Orphelin, Jean-Matthieu, Varey, Emilie, Khammari, Amir, Dreno, Brigitte, Dompmartin, Anne

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13194928

Paper PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.

Stecher, Carmen, Battin, Claire, Leitner, Judith, Zettl, Markus, Grabmeier-Pfistershammer, Katharina, Höller, Christoph, Zlabinger, Gerhard J, Steinberger, Peter · 2017 · Frontiers in immunology · DOI

Full title: PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.

Authors: Stecher, Carmen, Battin, Claire, Leitner, Judith, Zettl, Markus, Grabmeier-Pfistershammer, Katharina, Höller, Christoph, Zlabinger, Gerhard J, Steinberger, Peter

Year: 2017

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2017.00572

Paper Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

Katsuki, Shohei, Takahashi, Yutaka, Tamari, Keisuke, Minami, Kazumasa, Takenaka, Wataru, Ibuki, Yoriko, Yamamoto, Junya, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko · 2022 · PLoS ONE · DOI

Full title: Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

Authors: Katsuki, Shohei, Takahashi, Yutaka, Tamari, Keisuke, Minami, Kazumasa, Takenaka, Wataru, Ibuki, Yoriko, Yamamoto, Junya, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko

Year: 2022

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0271205

Paper Drug resistance mechanism and reversal strategy in lung cancer immunotherapy.

Xu, Yishi, Liu, Yaqing, Ge, Yi, Li, Haozhe, Zhang, Yi, Wang, Liping · 2023 · Frontiers in pharmacology · DOI

Full title: Drug resistance mechanism and reversal strategy in lung cancer immunotherapy.

Authors: Xu, Yishi, Liu, Yaqing, Ge, Yi, Li, Haozhe, Zhang, Yi, Wang, Liping

Year: 2023

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2023.1230824

Paper Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retrospective, pharmacovigilance study using the FAERS database.

Fu, Zhiwen, Liu, Jinmei, Zhang, Cong, Hu, Huiping, Li, Shijun, Zhang, Yu, You, Ruxu · 2024 · Frontiers in pharmacology · DOI

Full title: Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retrospective, pharmacovigilance study using the FAERS database.

Authors: Fu, Zhiwen, Liu, Jinmei, Zhang, Cong, Hu, Huiping, Li, Shijun, Zhang, Yu, You, Ruxu

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1383212

Paper Combination Atezolizumab, Cobimetinib, and Vemurafenib as a Treatment Option in BRAF V600 Mutation-Positive Melanoma: Patient Selection and Perspectives.

Dugan, Michelle M, Perez, Matthew C, Karapetyan, Lilit, Zager, Jonathan S · 2024 · Cancer management and research · DOI

Full title: Combination Atezolizumab, Cobimetinib, and Vemurafenib as a Treatment Option in BRAF V600 Mutation-Positive Melanoma: Patient Selection and Perspectives.

Authors: Dugan, Michelle M, Perez, Matthew C, Karapetyan, Lilit, Zager, Jonathan S

Year: 2024

Venue: Cancer management and research

DOI: https://doi.org/10.2147/CMAR.S325514

Paper Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer: Current Status, Recent Advances, and Future Directions

Kamatham, Saivaishnavi, Shahjehan, Faisal, Kasi, Pashtoon Murtaza · 2019 · Current Colorectal Cancer Reports · DOI

Full title: Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer: Current Status, Recent Advances, and Future Directions

Authors: Kamatham, Saivaishnavi, Shahjehan, Faisal, Kasi, Pashtoon Murtaza

Year: 2019

Venue: Current Colorectal Cancer Reports

DOI: https://doi.org/10.1007/s11888-019-00437-z

Paper Advancements in Melanoma Treatment: A Review of PD-1 Inhibitors, T-VEC, mRNA Vaccines, and Tumor-Infiltrating Lymphocyte Therapy in an Evolving Landscape of Immunotherapy.

Mehta, Apoorva, Motavaf, Mateen, Nebo, Ikenna, Luyten, Sophia, Osei-Opare, Kofi D, Gru, Alejandro A · 2025 · Journal of clinical medicine · DOI

Full title: Advancements in Melanoma Treatment: A Review of PD-1 Inhibitors, T-VEC, mRNA Vaccines, and Tumor-Infiltrating Lymphocyte Therapy in an Evolving Landscape of Immunotherapy.

Authors: Mehta, Apoorva, Motavaf, Mateen, Nebo, Ikenna, Luyten, Sophia, Osei-Opare, Kofi D, Gru, Alejandro A

Year: 2025

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm14041200

Paper Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer

Shindo, Yoshitaro, Hazama, Shoichi, Suzuki, Nobuaki, Iguchi, Haruo, Uesugi, Kazuhiro, Tanaka, Hiroaki, Aruga, Atsushi, Hatori, Takashi, Ishizaki, Hidenobu, Umeda, Yuzo, Fujiwara, Toshiyoshi, Ikemoto, Tetsuya, Shimada, Mitsuo, Yoshimatsu, Kazuhiko, Takenouchi, Hiroko, Matsui, Hiroto, Kanekiyo, Shinsuke, Iida, Michihisa, Yasunobu, Koki, Arima, Hideki, Furukawa, Hiroyuki, Ueno, Tomio, Yoshino, Shigefumi, Fujita, Tomonobu, Kawakami, Yutaka, Nakamura, Yusuke, Oka, Masaaki, Nagano, Hiroaki · 2017 · Journal of Experimental & Clinical Cancer Research · DOI

Full title: Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer

Authors: Shindo, Yoshitaro, Hazama, Shoichi, Suzuki, Nobuaki, Iguchi, Haruo, Uesugi, Kazuhiro, Tanaka, Hiroaki, Aruga, Atsushi, Hatori, Takashi, Ishizaki, Hidenobu, Umeda, Yuzo, Fujiwara, Toshiyoshi, Ikemoto, Tetsuya, Shimada, Mitsuo, Yoshimatsu, Kazuhiko, Takenouchi, Hiroko, Matsui, Hiroto, Kanekiyo, Shinsuke, Iida, Michihisa, Yasunobu, Koki, Arima, Hideki, Furukawa, Hiroyuki, Ueno, Tomio, Yoshino, Shigefumi, Fujita, Tomonobu, Kawakami, Yutaka, Nakamura, Yusuke, Oka, Masaaki, Nagano, Hiroaki

Year: 2017

Venue: Journal of Experimental & Clinical Cancer Research

DOI: https://doi.org/10.1186/s13046-017-0509-1

Paper What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 4: Experimental Treatments in Pre-Clinical Studies (Cell Lines and Mouse Models).

Palicelli, Andrea, Croci, Stefania, Bisagni, Alessandra, Zanetti, Eleonora, De Biase, Dario, Melli, Beatrice, Sanguedolce, Francesca, Ragazzi, Moira, Zanelli, Magda, Chaux, Alcides, Cañete-Portillo, Sofia, Bonasoni, Maria Paola, Soriano, Alessandra, Ascani, Stefano, Zizzo, Maurizio, Castro Ruiz, Carolina, De Leo, Antonio, Giordano, Guido, Landriscina, Matteo, Carrieri, Giuseppe, Cormio, Luigi, Berney, Daniel M, Gandhi, Jatin, Santandrea, Giacomo, Bonacini, Martina · 2021 · International journal of molecular sciences · DOI

Full title: What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 4: Experimental Treatments in Pre-Clinical Studies (Cell Lines and Mouse Models).

Authors: Palicelli, Andrea, Croci, Stefania, Bisagni, Alessandra, Zanetti, Eleonora, De Biase, Dario, Melli, Beatrice, Sanguedolce, Francesca, Ragazzi, Moira, Zanelli, Magda, Chaux, Alcides, Cañete-Portillo, Sofia, Bonasoni, Maria Paola, Soriano, Alessandra, Ascani, Stefano, Zizzo, Maurizio, Castro Ruiz, Carolina, De Leo, Antonio, Giordano, Guido, Landriscina, Matteo, Carrieri, Giuseppe, Cormio, Luigi, Berney, Daniel M, Gandhi, Jatin, Santandrea, Giacomo, Bonacini, Martina

Year: 2021

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms222212297

Paper Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

Young, Kristina H, Baird, Jason R, Savage, Talicia, Cottam, Benjamin, Friedman, David, Bambina, Shelly, Messenheimer, David J, Fox, Bernard, Newell, Pippa, Bahjat, Keith S, Gough, Michael J, Crittenden, Marka R · 2016 · PloS one · DOI

Full title: Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

Authors: Young, Kristina H, Baird, Jason R, Savage, Talicia, Cottam, Benjamin, Friedman, David, Bambina, Shelly, Messenheimer, David J, Fox, Bernard, Newell, Pippa, Bahjat, Keith S, Gough, Michael J, Crittenden, Marka R

Year: 2016

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0157164

Paper Immune-Based Combination Therapies for Advanced Hepatocellular Carcinoma.

Carloni, Riccardo, Sabbioni, Simone, Rizzo, Alessandro, Ricci, Angela Dalia, Palloni, Andrea, Petrarota, Cataldo, Cusmai, Antonio, Tavolari, Simona, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni · 2023 · Journal of hepatocellular carcinoma · DOI

Full title: Immune-Based Combination Therapies for Advanced Hepatocellular Carcinoma.

Authors: Carloni, Riccardo, Sabbioni, Simone, Rizzo, Alessandro, Ricci, Angela Dalia, Palloni, Andrea, Petrarota, Cataldo, Cusmai, Antonio, Tavolari, Simona, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni

Year: 2023

Venue: Journal of hepatocellular carcinoma

DOI: https://doi.org/10.2147/JHC.S390963

Paper Advanced nanotechnology in enhancing immune checkpoint inhibitors (ICIs) for head and neck cancer therapy.

Jafari, Zahra, Raoufi, Atieh, Athari, Seyyed Shamsadin, Bahramkiya, Sara, Jafari, Davood · 2025 · Cell communication and signaling : CCS · DOI

Full title: Advanced nanotechnology in enhancing immune checkpoint inhibitors (ICIs) for head and neck cancer therapy.

Authors: Jafari, Zahra, Raoufi, Atieh, Athari, Seyyed Shamsadin, Bahramkiya, Sara, Jafari, Davood

Year: 2025

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-025-02610-4

Paper Update in Immunotherapy for Advanced Non-Small Cell Lung Cancer: Optimizing Treatment Sequencing and Identifying the Best Choices.

Roque, Katia, Ruiz, Rossana, Mas, Luis, Pozza, Daniel Humberto, Vancini, Marina, Silva Júnior, José Antônio, de Mello, Ramon Andrade · 2023 · Cancers · DOI

Full title: Update in Immunotherapy for Advanced Non-Small Cell Lung Cancer: Optimizing Treatment Sequencing and Identifying the Best Choices.

Authors: Roque, Katia, Ruiz, Rossana, Mas, Luis, Pozza, Daniel Humberto, Vancini, Marina, Silva Júnior, José Antônio, de Mello, Ramon Andrade

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15184547

Paper Treatment of intracranial inflammatory myofibroblastic tumor with PD-L1 inhibitor and novel oncolytic adenovirus Ad-TD-nsIL12: a case report and literature review.

Qian, Xiao, Ning, Weihai, Dunmall, Louisa Chard, Qu, Yanming, Wang, Yaohe, Zhang, Hongwei · 2024 · Frontiers in immunology · DOI

Full title: Treatment of intracranial inflammatory myofibroblastic tumor with PD-L1 inhibitor and novel oncolytic adenovirus Ad-TD-nsIL12: a case report and literature review.

Authors: Qian, Xiao, Ning, Weihai, Dunmall, Louisa Chard, Qu, Yanming, Wang, Yaohe, Zhang, Hongwei

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1427554

Paper Association between effector-type regulatory T cells and immune checkpoint expression on CD8+ T cells in malignant ascites from epithelial ovarian cancer

Sato, Sho, Matsushita, Hirokazu, Shintani, Daisuke, Kobayashi, Yukari, Fujieda, Nao, Yabuno, Akira, Nishikawa, Tadaaki, Fujiwara, Keiichi, Kakimi, Kazuhiro, Hasegawa, Kosei · 2022 · BMC Cancer · DOI

Full title: Association between effector-type regulatory T cells and immune checkpoint expression on CD8+ T cells in malignant ascites from epithelial ovarian cancer

Authors: Sato, Sho, Matsushita, Hirokazu, Shintani, Daisuke, Kobayashi, Yukari, Fujieda, Nao, Yabuno, Akira, Nishikawa, Tadaaki, Fujiwara, Keiichi, Kakimi, Kazuhiro, Hasegawa, Kosei

Year: 2022

Venue: BMC Cancer

DOI: https://doi.org/10.1186/s12885-022-09534-z

Paper Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma

Hattinger, Claudia Maria, Salaroglio, Iris C., Fantoni, Leonardo, Godel, Martina, Casotti, Chiara, Kopecka, Joanna, Scotlandi, Katia, Ibrahim, Toni, Riganti, Chiara, Serra, Massimo · 2023 · International Journal of Molecular Sciences · DOI

Full title: Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma

Authors: Hattinger, Claudia Maria, Salaroglio, Iris C., Fantoni, Leonardo, Godel, Martina, Casotti, Chiara, Kopecka, Joanna, Scotlandi, Katia, Ibrahim, Toni, Riganti, Chiara, Serra, Massimo

Year: 2023

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms24010799

Paper Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis.

van der Leij, Stephanie, Suijkerbuijk, Karijn P M, van den Broek, Medard F M, Valk, Gerlof D, Dankbaar, Jan Willem, van Santen, Hanneke M · 2024 · Frontiers in endocrinology · DOI

Full title: Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis.

Authors: van der Leij, Stephanie, Suijkerbuijk, Karijn P M, van den Broek, Medard F M, Valk, Gerlof D, Dankbaar, Jan Willem, van Santen, Hanneke M

Year: 2024

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2024.1400841

Paper The Dual Blockade of the TIGIT and PD-1/PD-L1 Pathway as a New Hope for Ovarian Cancer Patients

Pawłowska, Anna, Skiba, Wiktoria, Suszczyk, Dorota, Kuryło, Weronika, Jakubowicz-Gil, Joanna, Paduch, Roman, Wertel, Iwona · 2022 · Cancers · DOI

Full title: The Dual Blockade of the TIGIT and PD-1/PD-L1 Pathway as a New Hope for Ovarian Cancer Patients

Authors: Pawłowska, Anna, Skiba, Wiktoria, Suszczyk, Dorota, Kuryło, Weronika, Jakubowicz-Gil, Joanna, Paduch, Roman, Wertel, Iwona

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14235757

Paper DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.

Mullen, Nicholas J, Shukla, Surendra K, Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina, Santana, Juan F, Miklavcic, William R, LaBreck, Drew A, Mallareddy, Jayapal Reddy, Price, David H, Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B, Hollingsworth, Michael A, Singh, Pankaj K · 2024 · bioRxiv : the preprint server for biology · DOI

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.

Authors: Mullen, Nicholas J, Shukla, Surendra K, Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina, Santana, Juan F, Miklavcic, William R, LaBreck, Drew A, Mallareddy, Jayapal Reddy, Price, David H, Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B, Hollingsworth, Michael A, Singh, Pankaj K

Year: 2024

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.04.03.535399

Paper Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.

Gonzalez-Nieto, Lucas, Castro, Isabelle M, Bischof, Georg F, Shin, Young C, Ricciardi, Michael J, Bailey, Varian K, Dang, Christine M, Pedreño-Lopez, Nuria, Magnani, Diogo M, Ejima, Keisuke, Allison, David B, Gil, Hwi Min, Evans, David T, Rakasz, Eva G, Lifson, Jeffrey D, Desrosiers, Ronald C, Martins, Mauricio A · 2019 · PLoS pathogens · DOI

Full title: Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.

Authors: Gonzalez-Nieto, Lucas, Castro, Isabelle M, Bischof, Georg F, Shin, Young C, Ricciardi, Michael J, Bailey, Varian K, Dang, Christine M, Pedreño-Lopez, Nuria, Magnani, Diogo M, Ejima, Keisuke, Allison, David B, Gil, Hwi Min, Evans, David T, Rakasz, Eva G, Lifson, Jeffrey D, Desrosiers, Ronald C, Martins, Mauricio A

Year: 2019

Venue: PLoS pathogens

DOI: https://doi.org/10.1371/journal.ppat.1008015

Paper Metabolic Implications of Immune Checkpoint Proteins in Cancer.

Stirling, Elizabeth R, Bronson, Steven M, Mackert, Jessica D, Cook, Katherine L, Triozzi, Pierre L, Soto-Pantoja, David R · 2022 · Cells · DOI

Full title: Metabolic Implications of Immune Checkpoint Proteins in Cancer.

Authors: Stirling, Elizabeth R, Bronson, Steven M, Mackert, Jessica D, Cook, Katherine L, Triozzi, Pierre L, Soto-Pantoja, David R

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11010179

Paper Pseudomonas Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation in Preclinical Models.

Leshem, Yasmin, Pastan, Ira · 2019 · Toxins · DOI

Full title: Pseudomonas Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation in Preclinical Models.

Authors: Leshem, Yasmin, Pastan, Ira

Year: 2019

Venue: Toxins

DOI: https://doi.org/10.3390/toxins11010020

Paper Immunotherapeutic Approaches for Treating Hepatocellular Carcinoma.

Shen, Wanying, Chen, Yujie, Lei, Pan, Sheldon, Marisela, Sun, Yutong, Yao, Fan, Ma, Li · 2022 · Cancers · DOI

Full title: Immunotherapeutic Approaches for Treating Hepatocellular Carcinoma.

Authors: Shen, Wanying, Chen, Yujie, Lei, Pan, Sheldon, Marisela, Sun, Yutong, Yao, Fan, Ma, Li

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14205013

Paper Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

Remón, Jordi, Esteller, Laura, Taus, Álvaro · 2019 · Cancer Management and Research · DOI

Full title: Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

Authors: Remón, Jordi, Esteller, Laura, Taus, Álvaro

Year: 2019

Venue: Cancer Management and Research

DOI: https://doi.org/10.2147/cmar.s164935

Paper [The use of immune checkpoint inhibitors in routine oncology].

Schardt, Julian · 2020 · Zeitschrift fur Rheumatologie · DOI

Full title: [The use of immune checkpoint inhibitors in routine oncology].

Authors: Schardt, Julian

Year: 2020

Venue: Zeitschrift fur Rheumatologie

DOI: https://doi.org/10.1007/s00393-020-00876-2

Paper Neoadjuvant Immunotherapy for Localized Pancreatic Cancer: Challenges and Early Results.

Chick, Robert Connor, Gunderson, Andrew J, Rahman, Shafia, Cloyd, Jordan M · 2023 · Cancers · DOI

Full title: Neoadjuvant Immunotherapy for Localized Pancreatic Cancer: Challenges and Early Results.

Authors: Chick, Robert Connor, Gunderson, Andrew J, Rahman, Shafia, Cloyd, Jordan M

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15153967

Paper Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status and ethnic origin

Qiu, Junlin, Luo, Shuoming, Yin, Wenfeng, Guo, Keyu, Xiang, Yufei, Li, Xia, Liu, Zhenqi, Zhou, Zhiguang · 2022 · Frontiers in Immunology · DOI

Full title: Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status and ethnic origin

Authors: Qiu, Junlin, Luo, Shuoming, Yin, Wenfeng, Guo, Keyu, Xiang, Yufei, Li, Xia, Liu, Zhenqi, Zhou, Zhiguang

Year: 2022

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2022.968798

Paper Addressing the Elephant in the Immunotherapy Room: Effector T-Cell Priming versus Depletion of Regulatory T-Cells by Anti-CTLA-4 Therapy.

Hong, Megan M Y, Maleki Vareki, Saman · 2022 · Cancers · DOI

Full title: Addressing the Elephant in the Immunotherapy Room: Effector T-Cell Priming versus Depletion of Regulatory T-Cells by Anti-CTLA-4 Therapy.

Authors: Hong, Megan M Y, Maleki Vareki, Saman

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14061580

Paper Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer.

Cheng, Weishi, Kang, Kai, Zhao, Ailin, Wu, Yijun · 2024 · Journal of hematology & oncology · DOI

Full title: Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer.

Authors: Cheng, Weishi, Kang, Kai, Zhao, Ailin, Wu, Yijun

Year: 2024

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-024-01581-2

Paper Immunotherapy and Hepatocellular Cancer: Where Are We Now?

Valery, Marine, Cervantes, Baptiste, Samaha, Ramy, Gelli, Maximiliano, Smolenschi, Cristina, Fuerea, Alina, Tselikas, Lambros, Klotz-Prieux, Caroline, Hollebecque, Antoine, Boige, Valérie, Ducreux, Michel · 2022 · Cancers · DOI

Full title: Immunotherapy and Hepatocellular Cancer: Where Are We Now?

Authors: Valery, Marine, Cervantes, Baptiste, Samaha, Ramy, Gelli, Maximiliano, Smolenschi, Cristina, Fuerea, Alina, Tselikas, Lambros, Klotz-Prieux, Caroline, Hollebecque, Antoine, Boige, Valérie, Ducreux, Michel

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14184523

Paper Inhibition of Post-Surgery Tumour Recurrence via a Sprayable Chemoimmunotherapy Gel Releasing PD-L1 Antibody and Platelet-Derived Exosomes

Zhao, Jian, Ye, Hao, Qi, Lu, Wang, Kaiyuan, Chen, Xiaofeng, Song, Jiaxuan, Wang, Helin, Lu, Yutong, Cheng, Maosheng, He, Zhonggui, Zhai, Yinglei, Zhang, Haotian, Sun, Jin · 2021 · Research Square (Research Square) · DOI

Full title: Inhibition of Post-Surgery Tumour Recurrence via a Sprayable Chemoimmunotherapy Gel Releasing PD-L1 Antibody and Platelet-Derived Exosomes

Authors: Zhao, Jian, Ye, Hao, Qi, Lu, Wang, Kaiyuan, Chen, Xiaofeng, Song, Jiaxuan, Wang, Helin, Lu, Yutong, Cheng, Maosheng, He, Zhonggui, Zhai, Yinglei, Zhang, Haotian, Sun, Jin

Year: 2021

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-1056003/v1

Paper COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

G. Botti, F. Fratangelo, M. Cerrone, G. Liguori, M. Cantile, A. Anniciello, S. Scala, C. D’Alterio, Chiara Trimarco, A. Ianaro, G. Cirino, C. Caracò, M. Colombino, G. Palmieri, S. Pepe, P. Ascierto, Francesco Sabbatino, G. Scognamiglio · 2017 · Journal of Translational Medicine · DOI

Full title: COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

Authors: G. Botti, F. Fratangelo, M. Cerrone, G. Liguori, M. Cantile, A. Anniciello, S. Scala, C. D’Alterio, Chiara Trimarco, A. Ianaro, G. Cirino, C. Caracò, M. Colombino, G. Palmieri, S. Pepe, P. Ascierto, Francesco Sabbatino, G. Scognamiglio

Year: 2017

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-017-1150-7

Paper Immunotherapy for glioblastoma: the promise of combination strategies.

Bausart, Mathilde, Préat, Véronique, Malfanti, Alessio · 2022 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Immunotherapy for glioblastoma: the promise of combination strategies.

Authors: Bausart, Mathilde, Préat, Véronique, Malfanti, Alessio

Year: 2022

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-022-02251-2

Paper The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ for Immune Checkpoint Inhibitors Response in Metastatic Melanoma Patients: PROTOCOL TRIAL.

Erman, Ana, Ignjatović, Marija, Leskovšek, Katja, Miceska, Simona, Lampreht Tratar, Urša, Bošnjak, Maša, Kloboves Prevodnik, Veronika, Čemažar, Maja, Kandolf Sekulovič, Lidija, Avguštin, Gorazd, Ocvirk, Janja, Mesti, Tanja · 2023 · Biomedicines · DOI

Full title: The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ for Immune Checkpoint Inhibitors Response in Metastatic Melanoma Patients: PROTOCOL TRIAL.

Authors: Erman, Ana, Ignjatović, Marija, Leskovšek, Katja, Miceska, Simona, Lampreht Tratar, Urša, Bošnjak, Maša, Kloboves Prevodnik, Veronika, Čemažar, Maja, Kandolf Sekulovič, Lidija, Avguštin, Gorazd, Ocvirk, Janja, Mesti, Tanja

Year: 2023

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines11072016

Paper Relationship between single-nucleotide polymorphisms and cancer immunotherapy efficacy and toxicity: a systematic review.

Specchia, Monia, Siringo, Marco, Mazzotti, Eva, Mazzuca, Federica · 2025 · Frontiers in oncology · DOI

Full title: Relationship between single-nucleotide polymorphisms and cancer immunotherapy efficacy and toxicity: a systematic review.

Authors: Specchia, Monia, Siringo, Marco, Mazzotti, Eva, Mazzuca, Federica

Year: 2025

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2025.1653990

Paper HLA-G and Other Immune Checkpoint Molecules as Targets for Novel Combined Immunotherapies.

Morandi, Fabio, Airoldi, Irma · 2022 · International journal of molecular sciences · DOI

Full title: HLA-G and Other Immune Checkpoint Molecules as Targets for Novel Combined Immunotherapies.

Authors: Morandi, Fabio, Airoldi, Irma

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms23062925

Paper A Comprehensive Review of Immunotherapeutic Modalities in Glioblastoma: Mechanisms, Efficacy, and Safety Considerations †.

Agarwal, Savi, Han, Simon, Lal, Aadi, Vira, Viranshi, Chandla, Anubhav, Mehranpour, Pasha, Yang, Isaac, Wadehra, Madhuri · 2026 · Cancers · DOI

Full title: A Comprehensive Review of Immunotherapeutic Modalities in Glioblastoma: Mechanisms, Efficacy, and Safety Considerations †.

Authors: Agarwal, Savi, Han, Simon, Lal, Aadi, Vira, Viranshi, Chandla, Anubhav, Mehranpour, Pasha, Yang, Isaac, Wadehra, Madhuri

Year: 2026

Venue: Cancers

DOI: https://doi.org/10.3390/cancers18020212

Paper Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach.

Kim, Chang-Gon, Sang, Yun-Beom, Lee, Ji-Hyun, Chon, Hong-Jae · 2021 · International journal of molecular sciences · DOI

Full title: Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach.

Authors: Kim, Chang-Gon, Sang, Yun-Beom, Lee, Ji-Hyun, Chon, Hong-Jae

Year: 2021

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms22158035

Paper Response to apatinib and camrelizumab combined treatment in a radioiodine refractory differentiated thyroid cancer patient resistant to prior anti-angiogenic therapy: A case report and literature review.

Li, Jiayi, Zhang, Xin, Mu, Zhuanzhuan, Sun, Di, Sun, Yuqing, Lin, Yansong · 2022 · Frontiers in immunology · DOI

Full title: Response to apatinib and camrelizumab combined treatment in a radioiodine refractory differentiated thyroid cancer patient resistant to prior anti-angiogenic therapy: A case report and literature review.

Authors: Li, Jiayi, Zhang, Xin, Mu, Zhuanzhuan, Sun, Di, Sun, Yuqing, Lin, Yansong

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.943916

Paper PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma

J. Park, M. Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, W. S. Jang, Won Sik Ham · 2024 · Cancer Cell International · DOI

Full title: PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma

Authors: J. Park, M. Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, W. S. Jang, Won Sik Ham

Year: 2024

Venue: Cancer Cell International

DOI: https://doi.org/10.1186/s12935-024-03238-z

Paper Untitled

Casaluce, Francesca, Gridelli, Cesare, Gridelli, Cesare, Topalian, S, Hodi, F, Brahmer, J, Brahmer, J, Tykodi, S, Chow, L, Carbone, D, Reck, M, Paz-Ares, L, Lopes, G, Wu, Y-L, Kudaba, I, Brahmer, J, Rodrguez-Abreu, D, Robinson, Hellmann, M, Ciuleanu, T, Pluzanski, A, Ramalingam, S, Hellmann, M, Awad, M, Hellmann, M, Paz-Ares, L, Caro, Bernabe, R, Paz-Ares, L, Ciuleanu, T, Yu, X, Ramalingam, S, Ciuleanu, T, Pluzanski, A, Reck, M, Ciuleanu, T-E, Dols, M, Gandhi, L, Rodrguez-Abreu, D, Gadgeel, S, Et, Rodriguez-Abreu, D, Powell, S, Hochmair, M, Paz-Ares, L, Luft, A, Vicente, D, West, H, Mccleod, M, Hussein, M · 2021 · International Journal of Clinical Studies and Medical Case Reports · DOI

Full title: Untitled

Authors: Casaluce, Francesca, Gridelli, Cesare, Gridelli, Cesare, Topalian, S, Hodi, F, Brahmer, J, Brahmer, J, Tykodi, S, Chow, L, Carbone, D, Reck, M, Paz-Ares, L, Lopes, G, Wu, Y-L, Kudaba, I, Brahmer, J, Rodrguez-Abreu, D, Robinson, Hellmann, M, Ciuleanu, T, Pluzanski, A, Ramalingam, S, Hellmann, M, Awad, M, Hellmann, M, Paz-Ares, L, Caro, Bernabe, R, Paz-Ares, L, Ciuleanu, T, Yu, X, Ramalingam, S, Ciuleanu, T, Pluzanski, A, Reck, M, Ciuleanu, T-E, Dols, M, Gandhi, L, Rodrguez-Abreu, D, Gadgeel, S, Et, Rodriguez-Abreu, D, Powell, S, Hochmair, M, Paz-Ares, L, Luft, A, Vicente, D, West, H, Mccleod, M, Hussein, M

Year: 2021

Venue: International Journal of Clinical Studies and Medical Case Reports

DOI: https://doi.org/10.46998/ijcmcr.8.5

Paper Dual immune checkpoint blockade in gastroesophageal tumors: never say never

A. Ilhan-Mutlu · 2023 · memo - Magazine of European Medical Oncology · DOI

Full title: Dual immune checkpoint blockade in gastroesophageal tumors: never say never

Authors: A. Ilhan-Mutlu

Year: 2023

Venue: memo - Magazine of European Medical Oncology

DOI: https://doi.org/10.1007/s12254-022-00870-1

Paper Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy.

Brilli, L, Danielli, R, Campanile, M, Secchi, C, Ciuoli, C, Calabrò, L, Pilli, T, Cartocci, A, Pacini, F, Di Giacomo, A M, Castagna, M G · 2021 · Journal of endocrinological investigation · DOI

Full title: Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy.

Authors: Brilli, L, Danielli, R, Campanile, M, Secchi, C, Ciuoli, C, Calabrò, L, Pilli, T, Cartocci, A, Pacini, F, Di Giacomo, A M, Castagna, M G

Year: 2021

Venue: Journal of endocrinological investigation

DOI: https://doi.org/10.1007/s40618-020-01480-6

Paper PD-1/PD-L1 inhibitors for early and middle stage microsatellite high-instability and stable colorectal cancer: a review.

Wu, Huiming, Deng, Min, Xue, Dingwen, Guo, Renkai, Zhang, Chenyu, Gao, Jiaqi, Li, Huiyu · 2024 · International journal of colorectal disease · DOI

Full title: PD-1/PD-L1 inhibitors for early and middle stage microsatellite high-instability and stable colorectal cancer: a review.

Authors: Wu, Huiming, Deng, Min, Xue, Dingwen, Guo, Renkai, Zhang, Chenyu, Gao, Jiaqi, Li, Huiyu

Year: 2024

Venue: International journal of colorectal disease

DOI: https://doi.org/10.1007/s00384-024-04654-3

Paper Strategies for treating the cold tumors of cholangiocarcinoma: core concepts and future directions.

Zhang, GuanBo, Li, JinSong, Li, Gang, Zhang, Jie, Yang, Zhi, Yang, Lin, Jiang, ShiJie, Wang, JiaXing · 2024 · Clinical and experimental medicine · DOI

Full title: Strategies for treating the cold tumors of cholangiocarcinoma: core concepts and future directions.

Authors: Zhang, GuanBo, Li, JinSong, Li, Gang, Zhang, Jie, Yang, Zhi, Yang, Lin, Jiang, ShiJie, Wang, JiaXing

Year: 2024

Venue: Clinical and experimental medicine

DOI: https://doi.org/10.1007/s10238-024-01460-7

Paper Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

Liu, Wai Nam, Fong, Shin Yie, Tan, Wilson Wei Sheng, Tan, Sue Yee, Liu, Min, Cheng, Jia Ying, Lim, Sherlly, Suteja, Lisda, Huang, Edwin Kunxiang, Chan, Jerry Kok Yen, Iyer, N. Gopalakrishna, Yeong, Joe, Lim, Wan‐Teck, Chen, Qingfeng · 2020 · Cancers · DOI

Full title: Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

Authors: Liu, Wai Nam, Fong, Shin Yie, Tan, Wilson Wei Sheng, Tan, Sue Yee, Liu, Min, Cheng, Jia Ying, Lim, Sherlly, Suteja, Lisda, Huang, Edwin Kunxiang, Chan, Jerry Kok Yen, Iyer, N. Gopalakrishna, Yeong, Joe, Lim, Wan‐Teck, Chen, Qingfeng

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12041025

Paper Total T Cell Density and Expression of T Memory Stem Cell Markers are Associated with Better Prognosis in Colon Cancer

Ding, Junli, Wang, Hao, Hou, Rui, Shi, Yuxin, Fan, Honghong, Li, Yuting, Mei, Jie, Zhang, Qinglin, Ruan, Tingyan, Xu, Junying · 2023 · International Journal of General Medicine · DOI

Full title: Total T Cell Density and Expression of T Memory Stem Cell Markers are Associated with Better Prognosis in Colon Cancer

Authors: Ding, Junli, Wang, Hao, Hou, Rui, Shi, Yuxin, Fan, Honghong, Li, Yuting, Mei, Jie, Zhang, Qinglin, Ruan, Tingyan, Xu, Junying

Year: 2023

Venue: International Journal of General Medicine

DOI: https://doi.org/10.2147/ijgm.s411122

Paper CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy.

Chen, Peifang, Pan, Jianrong, Chen, Ling, Feng, Xiushan · 2025 · Frontiers in oncology · DOI

Full title: CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy.

Authors: Chen, Peifang, Pan, Jianrong, Chen, Ling, Feng, Xiushan

Year: 2025

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2025.1670033

Paper Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials

Yang, Xing, Yasinjan, Feroza, Du, Yajie, Geng, Huayue, Zhang, Ying, He, Minghua, Guo, Rui, Yang, Lei, Cui, Jiayue, Mu, Dongmei, Liu, Ziling, Wang, Hong · 2023 · Frontiers in Immunology · DOI

Full title: Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials

Authors: Yang, Xing, Yasinjan, Feroza, Du, Yajie, Geng, Huayue, Zhang, Ying, He, Minghua, Guo, Rui, Yang, Lei, Cui, Jiayue, Mu, Dongmei, Liu, Ziling, Wang, Hong

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1094437

Paper Efficacy and safety of nurulimab+prolgolimab with continued prolgolimab therapy compared to prolgolimab alone as first-line therapy in patients with unresectable or metastatic melanoma: final results of the phase II OBERTON clinical study

I. Samoylenko, Lev V. Demidov, F. Moiseenko, M. Dvorkin, S. Demidova, S. Protsenko, D. Stroyakovskiy, V. Kozlov, S. Odintsova, Dmitry Kirtbaya, D. Tantsyrev, A. Mochalova, R. Orlova, G. Mukhametshina, N. Fadeeva, Evgeny A. Fomin, Yana S. Chapko, Anna V. Tarasova, N. B. Ermakov, Alexander K. Shemerovskiy, Vera A. Vaschenko, Valery M. Chistyakov, A. Zinkina-Orikhan, Yu. N. Lin’kova, F. Kryukov, I. Sorokina, A. Siliutina · 2023 · Journal of Modern Oncology · DOI

Full title: Efficacy and safety of nurulimab+prolgolimab with continued prolgolimab therapy compared to prolgolimab alone as first-line therapy in patients with unresectable or metastatic melanoma: final results of the phase II OBERTON clinical study

Authors: I. Samoylenko, Lev V. Demidov, F. Moiseenko, M. Dvorkin, S. Demidova, S. Protsenko, D. Stroyakovskiy, V. Kozlov, S. Odintsova, Dmitry Kirtbaya, D. Tantsyrev, A. Mochalova, R. Orlova, G. Mukhametshina, N. Fadeeva, Evgeny A. Fomin, Yana S. Chapko, Anna V. Tarasova, N. B. Ermakov, Alexander K. Shemerovskiy, Vera A. Vaschenko, Valery M. Chistyakov, A. Zinkina-Orikhan, Yu. N. Lin’kova, F. Kryukov, I. Sorokina, A. Siliutina

Year: 2023

Venue: Journal of Modern Oncology

DOI: https://doi.org/10.26442/18151434.2023.3.202463

Paper Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.

Pai, Chien-Chun Steven, Simons, Donald M, Lu, Xiaoqing, Evans, Michael, Wei, Junnian, Wang, Yung-Hua, Chen, Mingyi, Huang, John, Park, Chanhyuk, Chang, Anthony, Wang, Jiaxi, Westmoreland, Susan, Beam, Christine, Banach, Dave, Bowley, Diana, Dong, Feng, Seagal, Jane, Ritacco, Wendy, Richardson, Paul L, Mitra, Soumya, Lynch, Grace, Bousquet, Pete, Mankovich, John, Kingsbury, Gillian, Fong, Lawrence · 2019 · The Journal of clinical investigation · DOI

Full title: Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.

Authors: Pai, Chien-Chun Steven, Simons, Donald M, Lu, Xiaoqing, Evans, Michael, Wei, Junnian, Wang, Yung-Hua, Chen, Mingyi, Huang, John, Park, Chanhyuk, Chang, Anthony, Wang, Jiaxi, Westmoreland, Susan, Beam, Christine, Banach, Dave, Bowley, Diana, Dong, Feng, Seagal, Jane, Ritacco, Wendy, Richardson, Paul L, Mitra, Soumya, Lynch, Grace, Bousquet, Pete, Mankovich, John, Kingsbury, Gillian, Fong, Lawrence

Year: 2019

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI123391

Paper Influence of T Cell Coinhibitory Molecules on CD8+ Recall Responses

Anna B. Morris, Layne E. Adams, M. Ford · 2018 · Frontiers in Immunology · DOI

Full title: Influence of T Cell Coinhibitory Molecules on CD8+ Recall Responses

Authors: Anna B. Morris, Layne E. Adams, M. Ford

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.01810

Paper Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity.

Lesterhuis, W Joost, Salmons, Joanne, Nowak, Anna K, Rozali, Esdy N, Khong, Andrea, Dick, Ian M, Harken, Julie A, Robinson, Bruce W, Lake, Richard A · 2013 · PloS one · DOI

Full title: Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity.

Authors: Lesterhuis, W Joost, Salmons, Joanne, Nowak, Anna K, Rozali, Esdy N, Khong, Andrea, Dick, Ian M, Harken, Julie A, Robinson, Bruce W, Lake, Richard A

Year: 2013

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0061895

Paper Current Advance of Immune Evasion Mechanisms and Emerging Immunotherapies in Renal Cell Carcinoma.

Jian, Yuli, Yang, Kangkang, Sun, Xiaoxin, Zhao, Jun, Huang, Kai, Aldanakh, Abdullah, Xu, Zhongyang, Wu, Haotian, Xu, Qiwei, Zhang, Lin, Xu, Chunyan, Yang, Deyong, Wang, Shujing · 2021 · Frontiers in immunology · DOI

Full title: Current Advance of Immune Evasion Mechanisms and Emerging Immunotherapies in Renal Cell Carcinoma.

Authors: Jian, Yuli, Yang, Kangkang, Sun, Xiaoxin, Zhao, Jun, Huang, Kai, Aldanakh, Abdullah, Xu, Zhongyang, Wu, Haotian, Xu, Qiwei, Zhang, Lin, Xu, Chunyan, Yang, Deyong, Wang, Shujing

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.639636

Paper Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors.

Irabor, Omoruyi Credit, Nelson, Nicolas, Shah, Yash, Niazi, Muneeb Khan, Poiset, Spencer, Storozynsky, Eugene, Singla, Dinender K, Hooper, Douglas Craig, Lu, Bo · 2022 · Frontiers in oncology · DOI

Full title: Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors.

Authors: Irabor, Omoruyi Credit, Nelson, Nicolas, Shah, Yash, Niazi, Muneeb Khan, Poiset, Spencer, Storozynsky, Eugene, Singla, Dinender K, Hooper, Douglas Craig, Lu, Bo

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.940127

Paper Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era.

Wang, Shaoli, Chen, Siying, Zhong, Qionglei, Liu, Yan · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era.

Authors: Wang, Shaoli, Chen, Siying, Zhong, Qionglei, Liu, Yan

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-022-04214-8

Paper Advances in targeted therapy and immunotherapy for melanoma (Review)

Qin, Ziyao, Zheng, Mei · 2023 · Experimental and Therapeutic Medicine · DOI

Full title: Advances in targeted therapy and immunotherapy for melanoma (Review)

Authors: Qin, Ziyao, Zheng, Mei

Year: 2023

Venue: Experimental and Therapeutic Medicine

DOI: https://doi.org/10.3892/etm.2023.12115

Paper CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.

Milotay, Gusztav, Little, Martin, Watson, Robert A, Muldoon, Dylan, MacKay, Sophie, Kurioka, Ayako, Tong, Orion, Taylor, Chelsea A, Nassiri, Isar, Webb, Louisa M, Akin-Adigun, Oluwafemi, Bremke, Julia, Ye, Weiyu, Sun, Bo, Sharma, Piyush Kumar, Cooper, Ros, Danielli, Sara, Santo, Flavia Matos, Verge de Los Aires, Alba, Niu, Guangyi, Cohen, Lea, Ng, Esther, Gilchrist, James J, Chong, Amanda Y, Mentzer, Alex, Woodcock, Victoria, Coupe, Nicholas, Payne, Miranda J, Youdell, Michael, Middleton, Mark R, Klenerman, Paul, Fairfax, Benjamin P · 2025 · Nature medicine · DOI

Full title: CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.

Authors: Milotay, Gusztav, Little, Martin, Watson, Robert A, Muldoon, Dylan, MacKay, Sophie, Kurioka, Ayako, Tong, Orion, Taylor, Chelsea A, Nassiri, Isar, Webb, Louisa M, Akin-Adigun, Oluwafemi, Bremke, Julia, Ye, Weiyu, Sun, Bo, Sharma, Piyush Kumar, Cooper, Ros, Danielli, Sara, Santo, Flavia Matos, Verge de Los Aires, Alba, Niu, Guangyi, Cohen, Lea, Ng, Esther, Gilchrist, James J, Chong, Amanda Y, Mentzer, Alex, Woodcock, Victoria, Coupe, Nicholas, Payne, Miranda J, Youdell, Michael, Middleton, Mark R, Klenerman, Paul, Fairfax, Benjamin P

Year: 2025

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-025-03647-1

Paper Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Patients With Colon Cancer and to Assist in Immunotherapy.

Xu, Boyang, Peng, Ziqi, Yan, Guanyu, Wang, Ningning, Chen, Moye, Yao, Xue, Sun, Mingjun, An, Yue · 2021 · Frontiers in genetics · DOI

Full title: Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Patients With Colon Cancer and to Assist in Immunotherapy.

Authors: Xu, Boyang, Peng, Ziqi, Yan, Guanyu, Wang, Ningning, Chen, Moye, Yao, Xue, Sun, Mingjun, An, Yue

Year: 2021

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2021.726387

Paper Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma.

Okita, Riki, Senoo, Tomoya, Mimura-Kimura, Yuka, Mimura, Yusuke, Murakami, Tomoyuki, Ikeda, Eiji, Okada, Masanori, Inokawa, Hidetoshi, Aoe, Keisuke · 2024 · Scientific reports · DOI

Full title: Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma.

Authors: Okita, Riki, Senoo, Tomoya, Mimura-Kimura, Yuka, Mimura, Yusuke, Murakami, Tomoyuki, Ikeda, Eiji, Okada, Masanori, Inokawa, Hidetoshi, Aoe, Keisuke

Year: 2024

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-024-66189-5

Paper Comparative Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Advanced Cancer: A Systematic Review and Meta-Analysis.

Yang, Yi, Jin, Gang, Pang, Yao, Huang, Yijie, Wang, Wenhao, Zhang, Hongyi, Tuo, Guangxin, Wu, Peng, Wang, Zequan, Zhu, Zijiang · 2020 · Frontiers in pharmacology · DOI

Full title: Comparative Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Advanced Cancer: A Systematic Review and Meta-Analysis.

Authors: Yang, Yi, Jin, Gang, Pang, Yao, Huang, Yijie, Wang, Wenhao, Zhang, Hongyi, Tuo, Guangxin, Wu, Peng, Wang, Zequan, Zhu, Zijiang

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00040

Paper Immuno-Oncology: Emerging Targets and Combination Therapies.

Marshall, Henry T, Djamgoz, Mustafa B A · 2018 · Frontiers in oncology · DOI

Full title: Immuno-Oncology: Emerging Targets and Combination Therapies.

Authors: Marshall, Henry T, Djamgoz, Mustafa B A

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00315

Paper Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

Paulson, Kelly G., Voillet, Valentin, McAfee, Megan S., Hunter, Daniel, Wagener, Felecia, Perdicchio, Maurizio, Valente, William J., Koelle, Samson, Church, Candice D., Vandeven, Natalie, Thomas, Hannah, Colunga, Aric, Iyer, Jayasri G., Yee, Cassian, Kulikauskas, Rima M., Koelle, David M., Pierce, Robert H., Bielas, Jason H., Greenberg, Philip D., Bhatia, Shailender, Gottardo, Raphaël, Nghiem, Paul, Chapuis, Aude G. · 2018 · Nature Communications · DOI

Full title: Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

Authors: Paulson, Kelly G., Voillet, Valentin, McAfee, Megan S., Hunter, Daniel, Wagener, Felecia, Perdicchio, Maurizio, Valente, William J., Koelle, Samson, Church, Candice D., Vandeven, Natalie, Thomas, Hannah, Colunga, Aric, Iyer, Jayasri G., Yee, Cassian, Kulikauskas, Rima M., Koelle, David M., Pierce, Robert H., Bielas, Jason H., Greenberg, Philip D., Bhatia, Shailender, Gottardo, Raphaël, Nghiem, Paul, Chapuis, Aude G.

Year: 2018

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-018-06300-3

Paper PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

Xu-Monette, Zijun Y, Zhang, Mingzhi, Li, Jianyong, Young, Ken H · 2017 · Frontiers in immunology · DOI

Full title: PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

Authors: Xu-Monette, Zijun Y, Zhang, Mingzhi, Li, Jianyong, Young, Ken H

Year: 2017

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2017.01597

Paper β-adrenergic signaling blockade attenuates metastasis through activation of cytotoxic CD4 T cells.

Fjæstad, Klaire Yixin, Johansen, Astrid Zedlitz, Linder, Hannes, Baker, Kevin James, Schattefor, Milou, Czajkowski, Nadia Kolvig, Thorseth, Marie-Louise, Siersbæk, Majken, Kurzay, Annina, Perez-Penco, Maria, Rahbech, Anne, Saló, Sara Fresnillo, Engelholm, Lars Henning, Svane, Inge Marie, Andersen, Mads Hald, Junker, Niels, Grøntved, Lars, Straten, Per Thor, Madsen, Daniel Hargbøl · 2025 · Nature communications · DOI

Full title: β-adrenergic signaling blockade attenuates metastasis through activation of cytotoxic CD4 T cells.

Authors: Fjæstad, Klaire Yixin, Johansen, Astrid Zedlitz, Linder, Hannes, Baker, Kevin James, Schattefor, Milou, Czajkowski, Nadia Kolvig, Thorseth, Marie-Louise, Siersbæk, Majken, Kurzay, Annina, Perez-Penco, Maria, Rahbech, Anne, Saló, Sara Fresnillo, Engelholm, Lars Henning, Svane, Inge Marie, Andersen, Mads Hald, Junker, Niels, Grøntved, Lars, Straten, Per Thor, Madsen, Daniel Hargbøl

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-65048-9

Paper Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice.

Affolter, Timothy, Llewellyn, Heather P, Bartlett, Derek W, Zong, Qing, Xia, Shuhua, Torti, Vince, Ji, Changhua · 2019 · PloS one · DOI

Full title: Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice.

Authors: Affolter, Timothy, Llewellyn, Heather P, Bartlett, Derek W, Zong, Qing, Xia, Shuhua, Torti, Vince, Ji, Changhua

Year: 2019

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0217276

Paper Cure the Incurable? Recent Breakthroughs in Immune Checkpoint Blockade for Hepatocellular Carcinoma.

Chu, Pei-Yi, Chan, Shih-Hsuan · 2021 · Cancers · DOI

Full title: Cure the Incurable? Recent Breakthroughs in Immune Checkpoint Blockade for Hepatocellular Carcinoma.

Authors: Chu, Pei-Yi, Chan, Shih-Hsuan

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13215295

Paper Immunotherapy for Thymomas and Thymic Carcinomas: Current Status and Future Directions

Rajan, Arun, Sivapiromrat, Alisa K., McAdams, Meredith J. · 2024 · Cancers · DOI

Full title: Immunotherapy for Thymomas and Thymic Carcinomas: Current Status and Future Directions

Authors: Rajan, Arun, Sivapiromrat, Alisa K., McAdams, Meredith J.

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16071369

Paper Mechanisms underlying response and resistance to immune checkpoint blockade in cancer immunotherapy.

Lee, Junghwa, Kim, Eui Ho · 2023 · Frontiers in oncology · DOI

Full title: Mechanisms underlying response and resistance to immune checkpoint blockade in cancer immunotherapy.

Authors: Lee, Junghwa, Kim, Eui Ho

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1233376

Paper Combined treatment of HCC with CTLA-4 inhibitors and PD-1/PD-L1 inhibitors: mechanisms, progress and challenges

Wang, Lan · 2025 · Theoretical and Natural Science · DOI

Full title: Combined treatment of HCC with CTLA-4 inhibitors and PD-1/PD-L1 inhibitors: mechanisms, progress and challenges

Authors: Wang, Lan

Year: 2025

Venue: Theoretical and Natural Science

DOI: https://doi.org/10.54254/2753-8818/2025.19705

Paper Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment

Cao, Guangxu, Yue, Jiali, Ruan, Yetian, Han, Ya, Zhi, Yong, Lu, Jianqiao, Liu, Min, Xu, Xinxin, Wang, Jin, Gu, Quan, Wen, Xuejun, Gao, Jinli, Zhang, Qingfeng, Kang, Jiuhong, Wang, Chenfei, Li, Fang · 2023 · The EMBO Journal · DOI

Full title: Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment

Authors: Cao, Guangxu, Yue, Jiali, Ruan, Yetian, Han, Ya, Zhi, Yong, Lu, Jianqiao, Liu, Min, Xu, Xinxin, Wang, Jin, Gu, Quan, Wen, Xuejun, Gao, Jinli, Zhang, Qingfeng, Kang, Jiuhong, Wang, Chenfei, Li, Fang

Year: 2023

Venue: The EMBO Journal

DOI: https://doi.org/10.15252/embj.2022110757

Paper Rapid Melanoma Death of an Adult Male with Congenital Bathing Trunk Nevus despite Initiation of Combination Immunotherapy

Gambichler, Thilo, Noldes, Kathrin, Arafat, Yousef, Neid, Matthias, Rütten, Arno, Boms, Stefanie · 2023 · Dermato · DOI

Full title: Rapid Melanoma Death of an Adult Male with Congenital Bathing Trunk Nevus despite Initiation of Combination Immunotherapy

Authors: Gambichler, Thilo, Noldes, Kathrin, Arafat, Yousef, Neid, Matthias, Rütten, Arno, Boms, Stefanie

Year: 2023

Venue: Dermato

DOI: https://doi.org/10.3390/dermato3010004

Paper Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy.

Larimer, Benjamin M, Wehrenberg-Klee, Eric, Caraballo, Alexander, Mahmood, Umar · 2016 · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · DOI

Full title: Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy.

Authors: Larimer, Benjamin M, Wehrenberg-Klee, Eric, Caraballo, Alexander, Mahmood, Umar

Year: 2016

Venue: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

DOI: https://doi.org/10.2967/jnumed.116.173930

Paper TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity.

Panagi, Myrofora, Voutouri, Chrysovalantis, Mpekris, Fotios, Papageorgis, Panagiotis, Martin, Margaret R, Martin, John D, Demetriou, Philippos, Pierides, Chryso, Polydorou, Christiana, Stylianou, Andreas, Louca, Maria, Koumas, Laura, Costeas, Paul, Kataoka, Kazunori, Cabral, Horacio, Stylianopoulos, Triantafyllos · 2020 · Theranostics · DOI

Full title: TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity.

Authors: Panagi, Myrofora, Voutouri, Chrysovalantis, Mpekris, Fotios, Papageorgis, Panagiotis, Martin, Margaret R, Martin, John D, Demetriou, Philippos, Pierides, Chryso, Polydorou, Christiana, Stylianou, Andreas, Louca, Maria, Koumas, Laura, Costeas, Paul, Kataoka, Kazunori, Cabral, Horacio, Stylianopoulos, Triantafyllos

Year: 2020

Venue: Theranostics

DOI: https://doi.org/10.7150/thno.36936

Paper Neoadjuvant chemoradiotherapy with or without PD-1/PD-L1 inhibitors in locally advanced rectal cancer: a systematic review and meta-analysis.

Ansab, Muhammad, Razi, Sepideh, Nisa, Farwa, Araib, Eiman, Rath, Shree, Khan, Iqra, Ramzan, Noor Ul Huda, Dilawar, Esha, Saeed, Anwaar · 2025 · BMC cancer · DOI

Full title: Neoadjuvant chemoradiotherapy with or without PD-1/PD-L1 inhibitors in locally advanced rectal cancer: a systematic review and meta-analysis.

Authors: Ansab, Muhammad, Razi, Sepideh, Nisa, Farwa, Araib, Eiman, Rath, Shree, Khan, Iqra, Ramzan, Noor Ul Huda, Dilawar, Esha, Saeed, Anwaar

Year: 2025

Venue: BMC cancer

DOI: https://doi.org/10.1186/s12885-025-14482-5

Paper Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma.

Khair, Duaa O, Bax, Heather J, Mele, Silvia, Crescioli, Silvia, Pellizzari, Giulia, Khiabany, Atousa, Nakamura, Mano, Harris, Robert J, French, Elise, Hoffmann, Ricarda M, Williams, Iwan P, Cheung, Anthony, Thair, Benjamin, Beales, Charlie T, Touizer, Emma, Signell, Adrian W, Tasnova, Nahrin L, Spicer, James F, Josephs, Debra H, Geh, Jenny L, MacKenzie Ross, Alastair, Healy, Ciaran, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N · 2019 · Frontiers in immunology · DOI

Full title: Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma.

Authors: Khair, Duaa O, Bax, Heather J, Mele, Silvia, Crescioli, Silvia, Pellizzari, Giulia, Khiabany, Atousa, Nakamura, Mano, Harris, Robert J, French, Elise, Hoffmann, Ricarda M, Williams, Iwan P, Cheung, Anthony, Thair, Benjamin, Beales, Charlie T, Touizer, Emma, Signell, Adrian W, Tasnova, Nahrin L, Spicer, James F, Josephs, Debra H, Geh, Jenny L, MacKenzie Ross, Alastair, Healy, Ciaran, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N

Year: 2019

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2019.00453

Paper Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail · 2020 · British Journal of Cancer · DOI

Full title: Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Authors: Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail

Year: 2020

Venue: British Journal of Cancer

DOI: https://doi.org/10.1038/s41416-020-01048-4

Paper PD-1/PD-L1 blockades in non-small-cell lung cancer therapy.

Jing, Wang, Li, Miaomiao, Zhang, Yan, Teng, Feifei, Han, Anqin, Kong, Li, Zhu, Hui · 2016 · OncoTargets and therapy · DOI

Full title: PD-1/PD-L1 blockades in non-small-cell lung cancer therapy.

Authors: Jing, Wang, Li, Miaomiao, Zhang, Yan, Teng, Feifei, Han, Anqin, Kong, Li, Zhu, Hui

Year: 2016

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S94993

Paper Is There a Role for Immunotherapy in Prostate Cancer?

Rizzo, Alessandro, Mollica, Veronica, Cimadamore, Alessia, Santoni, Matteo, Scarpelli, Marina, Giunchi, Francesca, Cheng, Liang, Lopez-Beltran, Antonio, Fiorentino, Michelangelo, Montironi, Rodolfo, Massari, Francesco · 2020 · Cells · DOI

Full title: Is There a Role for Immunotherapy in Prostate Cancer?

Authors: Rizzo, Alessandro, Mollica, Veronica, Cimadamore, Alessia, Santoni, Matteo, Scarpelli, Marina, Giunchi, Francesca, Cheng, Liang, Lopez-Beltran, Antonio, Fiorentino, Michelangelo, Montironi, Rodolfo, Massari, Francesco

Year: 2020

Venue: Cells

DOI: https://doi.org/10.3390/cells9092051

Paper A view on drug resistance in cancer

Vasan, Neil, Baselga, José, Hyman, David M. · 2019 · Nature · DOI

Full title: A view on drug resistance in cancer

Authors: Vasan, Neil, Baselga, José, Hyman, David M.

Year: 2019

Venue: Nature

DOI: https://doi.org/10.1038/s41586-019-1730-1

Paper Developing combination strategies using PD-1 checkpoint inhibitors to treat cancer.

Schmidt, Emmett V · 2019 · Seminars in immunopathology · DOI

Full title: Developing combination strategies using PD-1 checkpoint inhibitors to treat cancer.

Authors: Schmidt, Emmett V

Year: 2019

Venue: Seminars in immunopathology

DOI: https://doi.org/10.1007/s00281-018-0714-9

Paper Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.

Muthukutty, Palaniyandi, Heo, Jeong, Yoo, So Young · 2026 · Vaccines · DOI

Full title: Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.

Authors: Muthukutty, Palaniyandi, Heo, Jeong, Yoo, So Young

Year: 2026

Venue: Vaccines

DOI: https://doi.org/10.3390/vaccines14020189

Paper Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis.

Chang, Katherine C, Burnham, Carey-Ann, Compton, Stephanie M, Rasche, David P, Mazuski, Richard J, McDonough, Jacquelyn S, Unsinger, Jacqueline, Korman, Alan J, Green, Jonathan M, Hotchkiss, Richard S · 2013 · Critical care (London, England) · DOI

Full title: Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis.

Authors: Chang, Katherine C, Burnham, Carey-Ann, Compton, Stephanie M, Rasche, David P, Mazuski, Richard J, McDonough, Jacquelyn S, Unsinger, Jacqueline, Korman, Alan J, Green, Jonathan M, Hotchkiss, Richard S

Year: 2013

Venue: Critical care (London, England)

DOI: https://doi.org/10.1186/cc12711

Paper Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

Kabacaoglu, Derya, Ciecielski, Katrin J, Ruess, Dietrich A, Algül, Hana · 2018 · Frontiers in immunology · DOI

Full title: Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

Authors: Kabacaoglu, Derya, Ciecielski, Katrin J, Ruess, Dietrich A, Algül, Hana

Year: 2018

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2018.01878

Paper Immune Checkpoint Inhibitors: A New Opportunity in the Treatment of Ovarian Cancer?

Mittica, Gloria, Genta, Sofia, Aglietta, Massimo, Valabrega, Giorgio · 2016 · International journal of molecular sciences · DOI

Full title: Immune Checkpoint Inhibitors: A New Opportunity in the Treatment of Ovarian Cancer?

Authors: Mittica, Gloria, Genta, Sofia, Aglietta, Massimo, Valabrega, Giorgio

Year: 2016

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms17071169

Paper CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma

Khunger, Arjun, Piazza, Erin, Warren, Sarah, Smith, Thomas H., Ren, Xing, White, Andrew, Elliott, Nathan, Cesano, Alessandra, Beechem, Joseph, Kirkwood, John M., Tarhini, Ahmad A. · 2021 · PLoS ONE · DOI

Full title: CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma

Authors: Khunger, Arjun, Piazza, Erin, Warren, Sarah, Smith, Thomas H., Ren, Xing, White, Andrew, Elliott, Nathan, Cesano, Alessandra, Beechem, Joseph, Kirkwood, John M., Tarhini, Ahmad A.

Year: 2021

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0245287

Paper The Landscape of Immunotherapy in Advanced NSCLC: Driving Beyond PD-1/PD-L1 Inhibitors (CTLA-4, LAG3, IDO, OX40, TIGIT, Vaccines).

De Giglio, Andrea, Di Federico, Alessandro, Nuvola, Giacomo, Deiana, Chiara, Gelsomino, Francesco · 2021 · Current oncology reports · DOI

Full title: The Landscape of Immunotherapy in Advanced NSCLC: Driving Beyond PD-1/PD-L1 Inhibitors (CTLA-4, LAG3, IDO, OX40, TIGIT, Vaccines).

Authors: De Giglio, Andrea, Di Federico, Alessandro, Nuvola, Giacomo, Deiana, Chiara, Gelsomino, Francesco

Year: 2021

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-021-01124-9

Paper [First-line Combination Immunotherapy in Advanced Non-small Cell Lung Cancer].

Peng, Xiaoxiao, Zhou, Qing · 2018 · Zhongguo fei ai za zhi = Chinese journal of lung cancer · DOI

Full title: [First-line Combination Immunotherapy in Advanced Non-small Cell Lung Cancer].

Authors: Peng, Xiaoxiao, Zhou, Qing

Year: 2018

Venue: Zhongguo fei ai za zhi = Chinese journal of lung cancer

DOI: https://doi.org/10.3779/j.issn.1009-3419.2018.12.11

Paper PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy

Long, Junyu, Lin, Jianzhen, Wang, Anqiang, Wu, Liangcai, Zheng, Yongchang, Yang, Xiaobo, Wan, Xueshuai, Xu, Haifeng, Chen, Shuguang, Zhao, Haitao · 2017 · Journal of Hematology & Oncology · DOI

Full title: PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy

Authors: Long, Junyu, Lin, Jianzhen, Wang, Anqiang, Wu, Liangcai, Zheng, Yongchang, Yang, Xiaobo, Wan, Xueshuai, Xu, Haifeng, Chen, Shuguang, Zhao, Haitao

Year: 2017

Venue: Journal of Hematology & Oncology

DOI: https://doi.org/10.1186/s13045-017-0511-2

Paper Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies.

Puri, Sonam, Shafique, Michael · 2020 · Drugs in context · DOI

Full title: Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies.

Authors: Puri, Sonam, Shafique, Michael

Year: 2020

Venue: Drugs in context

DOI: https://doi.org/10.7573/dic.2019-9-2

Paper Efficacy and safety of immune checkpoint inhibitors for patients with prostate cancer: a systematic review and meta-analysis.

Noori, Maryam, Azizi, Shadi, Mahjoubfar, Aref, Abbasi Varaki, Farhan, Fayyaz, Farimah, Mousavian, Amir-Hossein, Bashash, Davood, Kardoust Parizi, Mehdi, Kasaeian, Amir · 2023 · Frontiers in immunology · DOI

Full title: Efficacy and safety of immune checkpoint inhibitors for patients with prostate cancer: a systematic review and meta-analysis.

Authors: Noori, Maryam, Azizi, Shadi, Mahjoubfar, Aref, Abbasi Varaki, Farhan, Fayyaz, Farimah, Mousavian, Amir-Hossein, Bashash, Davood, Kardoust Parizi, Mehdi, Kasaeian, Amir

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1181051

Paper A novel mouse model for checkpoint inhibitor-induced adverse events.

Adam, Kieran, Iuga, Alina, Tocheva, Anna S, Mor, Adam · 2021 · PloS one · DOI

Full title: A novel mouse model for checkpoint inhibitor-induced adverse events.

Authors: Adam, Kieran, Iuga, Alina, Tocheva, Anna S, Mor, Adam

Year: 2021

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0246168

Paper [Research Progress of Adverse Events Related to PD-1/PD-L1 Inhibitors Based Combination Therapy].

Guo, Xiaoyu, Wen, Ti, Qu, Xiujuan · 2021 · Zhongguo fei ai za zhi = Chinese journal of lung cancer · DOI

Full title: [Research Progress of Adverse Events Related to PD-1/PD-L1 Inhibitors Based Combination Therapy].

Authors: Guo, Xiaoyu, Wen, Ti, Qu, Xiujuan

Year: 2021

Venue: Zhongguo fei ai za zhi = Chinese journal of lung cancer

DOI: https://doi.org/10.3779/j.issn.1009-3419.2021.101.26

Paper Positive clinical outcomes following therapy with programmed cell death protein 1/programmed cell death ligand 1 inhibitors in neuroendocrine carcinoma of the cervix.

Liu, Rongyu, He, Xinlin, Li, Zhengyu · 2022 · Frontiers in pharmacology · DOI

Full title: Positive clinical outcomes following therapy with programmed cell death protein 1/programmed cell death ligand 1 inhibitors in neuroendocrine carcinoma of the cervix.

Authors: Liu, Rongyu, He, Xinlin, Li, Zhengyu

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.1029598

Paper Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

Bakhru, Pearl, Zhu, Meng-Lei, Wang, Hsing-Hui, Hong, Lee K, Khan, Imran, Mouchess, Maria, Gulati, Ajay S, Starmer, Joshua, Hou, Yafei, Sailer, David, Lee, Sandra, Zhao, Fengmin, Kirkwood, John M, Moschos, Stergios, Fong, Lawrence, Anderson, Mark S, Su, Maureen A · 2017 · JCI insight · DOI

Full title: Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

Authors: Bakhru, Pearl, Zhu, Meng-Lei, Wang, Hsing-Hui, Hong, Lee K, Khan, Imran, Mouchess, Maria, Gulati, Ajay S, Starmer, Joshua, Hou, Yafei, Sailer, David, Lee, Sandra, Zhao, Fengmin, Kirkwood, John M, Moschos, Stergios, Fong, Lawrence, Anderson, Mark S, Su, Maureen A

Year: 2017

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.93265

Paper The Abscopal Effect in the Era of Checkpoint Inhibitors.

Kodet, Ondřej, Němejcova, Kristýna, Strnadová, Karolína, Havlínová, Andrea, Dundr, Pavel, Krajsová, Ivana, Štork, Jiří, Smetana, Karel, Lacina, Lukáš · 2021 · International journal of molecular sciences · DOI

Full title: The Abscopal Effect in the Era of Checkpoint Inhibitors.

Authors: Kodet, Ondřej, Němejcova, Kristýna, Strnadová, Karolína, Havlínová, Andrea, Dundr, Pavel, Krajsová, Ivana, Štork, Jiří, Smetana, Karel, Lacina, Lukáš

Year: 2021

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms22137204

Paper Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy.

Jin, Xingyi, Qin, Zhigang, Zhao, Hang · 2024 · BMC immunology · DOI

Full title: Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy.

Authors: Jin, Xingyi, Qin, Zhigang, Zhao, Hang

Year: 2024

Venue: BMC immunology

DOI: https://doi.org/10.1186/s12865-024-00639-7

Paper Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring combined anti-PD-L1/anti-CTLA-4 immunotherapy effects in a murine melanoma model with immunohistochemical validation.

Herr, Felix L, Antons, Melissa J, Blume, Larissa V, Hirner-Eppeneder, Heidrun, Kloiber-Langhorst, Sandra, Cimic, Amra, Stueckl, Jennifer, Tardy, Isabelle, Burkard, Tanja, Ricke, Jens, Kunz, Wolfgang G, Clevert, Dirk-Andre, Heimer, Maurice M, Cyran, Clemens C · 2025 · PloS one · DOI

Full title: Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring combined anti-PD-L1/anti-CTLA-4 immunotherapy effects in a murine melanoma model with immunohistochemical validation.

Authors: Herr, Felix L, Antons, Melissa J, Blume, Larissa V, Hirner-Eppeneder, Heidrun, Kloiber-Langhorst, Sandra, Cimic, Amra, Stueckl, Jennifer, Tardy, Isabelle, Burkard, Tanja, Ricke, Jens, Kunz, Wolfgang G, Clevert, Dirk-Andre, Heimer, Maurice M, Cyran, Clemens C

Year: 2025

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0326675

Paper PD-1 and CTLA-4 serve as major gatekeepers for effector and cytotoxic T-cell potentiation by limiting a CXCL9/10-CXCR3-IFNγ positive feedback loop.

Abdala-Saleh, Noor, Lugassy, Jennie, Shivakumar-Kalvhati, Akshatha, Turky, Abeer, Abu Ras, Sari, Razon, Hila, Berger, Nir, Bar-On, Dana, Bar-On, Yotam, Taura, Tetsuya, Wilson, David, Karin, Nathan · 2024 · Frontiers in immunology · DOI

Full title: PD-1 and CTLA-4 serve as major gatekeepers for effector and cytotoxic T-cell potentiation by limiting a CXCL9/10-CXCR3-IFNγ positive feedback loop.

Authors: Abdala-Saleh, Noor, Lugassy, Jennie, Shivakumar-Kalvhati, Akshatha, Turky, Abeer, Abu Ras, Sari, Razon, Hila, Berger, Nir, Bar-On, Dana, Bar-On, Yotam, Taura, Tetsuya, Wilson, David, Karin, Nathan

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1452212

Paper Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody.

Azuma, Takeshi, Takeuchi, Takumi, Matayoshi, Yukihide, Namiki, Shin, Obara, Tetsuya, Imamura, Kazuhiro, Takamori, Mikio · 2021 · Scientific reports · DOI

Full title: Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody.

Authors: Azuma, Takeshi, Takeuchi, Takumi, Matayoshi, Yukihide, Namiki, Shin, Obara, Tetsuya, Imamura, Kazuhiro, Takamori, Mikio

Year: 2021

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-021-88744-0

Paper Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.

Davis-Marcisak, Emily F, Fitzgerald, Allison A, Kessler, Michael D, Danilova, Ludmila, Jaffee, Elizabeth M, Zaidi, Neeha, Weiner, Louis M, Fertig, Elana J · 2021 · Genome medicine · DOI

Full title: Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.

Authors: Davis-Marcisak, Emily F, Fitzgerald, Allison A, Kessler, Michael D, Danilova, Ludmila, Jaffee, Elizabeth M, Zaidi, Neeha, Weiner, Louis M, Fertig, Elana J

Year: 2021

Venue: Genome medicine

DOI: https://doi.org/10.1186/s13073-021-00944-5

Paper Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Small Cell Lung Cancer (NSCLC) In Vivo Model.

Barsheshet, Yiftah, Voloshin, Tali, Brant, Boris, Cohen, Gadi, Koren, Lilach, Blatt, Roni, Cahal, Shay, Haj Khalil, Tharwat, Zemer Tov, Efrat, Paz, Rom, Klein-Goldberg, Anat, Tempel-Brami, Catherine, Jacobovitch, Sara, Volodin, Alexandra, Kan, Tal, Koltun, Bella, David, Cfir, Haber, Adi, Giladi, Moshe, Weinberg, Uri, Palti, Yoram · 2022 · International journal of molecular sciences · DOI

Full title: Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Small Cell Lung Cancer (NSCLC) In Vivo Model.

Authors: Barsheshet, Yiftah, Voloshin, Tali, Brant, Boris, Cohen, Gadi, Koren, Lilach, Blatt, Roni, Cahal, Shay, Haj Khalil, Tharwat, Zemer Tov, Efrat, Paz, Rom, Klein-Goldberg, Anat, Tempel-Brami, Catherine, Jacobovitch, Sara, Volodin, Alexandra, Kan, Tal, Koltun, Bella, David, Cfir, Haber, Adi, Giladi, Moshe, Weinberg, Uri, Palti, Yoram

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232214073

Paper PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil.

Sorroche, Bruna Pereira, Teixeira, Renan de Jesus, Pereira, Caio Augusto Dantas, Santana, Iara Viana Vidigal, Vujanovic, Lazar, Vazquez, Vinicius de Lima, Arantes, Lidia Maria Rebolho Batista · 2023 · Diagnostics (Basel, Switzerland) · DOI

Full title: PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil.

Authors: Sorroche, Bruna Pereira, Teixeira, Renan de Jesus, Pereira, Caio Augusto Dantas, Santana, Iara Viana Vidigal, Vujanovic, Lazar, Vazquez, Vinicius de Lima, Arantes, Lidia Maria Rebolho Batista

Year: 2023

Venue: Diagnostics (Basel, Switzerland)

DOI: https://doi.org/10.3390/diagnostics13061041

Paper Table_1_FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: Safety Run-In of Phase II NIVACOR Trial.doc

(4877341), Angela Damato, (4780986), Francesca Bergamo, (11541011), Lorenzo Antonuzzo, (826156), Guglielmo Nasti, (11540978), Francesco Iachetta, (11541002), Alessandra Romagnani, (11834330), Erika Gervasi, (11834333), Mario Larocca, (336915), Carmine Pinto · 2021 · Figshare · DOI

Full title: Table_1_FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: Safety Run-In of Phase II NIVACOR Trial.doc

Authors: (4877341), Angela Damato, (4780986), Francesca Bergamo, (11541011), Lorenzo Antonuzzo, (826156), Guglielmo Nasti, (11540978), Francesco Iachetta, (11541002), Alessandra Romagnani, (11834330), Erika Gervasi, (11834333), Mario Larocca, (336915), Carmine Pinto

Year: 2021

Venue: Figshare

DOI: https://doi.org/10.3389/fonc.2021.766500.s001

Paper Current Status and Future Direction of Immunotherapy in Hepatocellular Carcinoma: What Do the Data Suggest?

Lee, Hye Won, Cho, Kyung Joo, Park, Jun Yong · 2020 · Immune network · DOI

Full title: Current Status and Future Direction of Immunotherapy in Hepatocellular Carcinoma: What Do the Data Suggest?

Authors: Lee, Hye Won, Cho, Kyung Joo, Park, Jun Yong

Year: 2020

Venue: Immune network

DOI: https://doi.org/10.4110/in.2020.20.e11

Paper Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients.

Troiani, Teresa, Giunta, Emilio Francesco, Tufano, Martina, Vigorito, Vincenza, Arrigo, Paolo D', Argenziano, Giuseppe, Ciardiello, Fortunato, Romano, Maria Fiammetta, Romano, Simona · 2020 · British journal of cancer · DOI

Full title: Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients.

Authors: Troiani, Teresa, Giunta, Emilio Francesco, Tufano, Martina, Vigorito, Vincenza, Arrigo, Paolo D', Argenziano, Giuseppe, Ciardiello, Fortunato, Romano, Maria Fiammetta, Romano, Simona

Year: 2020

Venue: British journal of cancer

DOI: https://doi.org/10.1038/s41416-020-0840-8

Paper Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities.

Jiao, Ruidi, Luo, Hui, Xu, Wenbo, Ge, Hong · 2019 · OncoTargets and therapy · DOI

Full title: Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities.

Authors: Jiao, Ruidi, Luo, Hui, Xu, Wenbo, Ge, Hong

Year: 2019

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S214579

Paper Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Georgina V. Long, E. Shklovskaya, L. Satgunaseelan, Yizhe Mao, I. D. da Silva, Kristen A Perry, R. Diefenbach, T. Gide, B. Shivalingam, Michael E Buckland, Maria Gonzalez, Nicole Caixeiro, I. A. Vergara, Xinyu Bai, R. Rawson, Edward Hsiao, U. Palendira, T. G. Phan, A. Menzies, Matteo S. Carlino, Camelia Quek, S. Grimmond, J. Vissers, D. Yeo, John E. J. Rasko, Mustafa Khasraw, B. Neyns, D. Reardon, David M. Ashley, Helen Wheeler, Michael Back, R. Scolyer, James Drummond, J. Wilmott, H. Rizos · 2025 · Nature Medicine · DOI

Full title: Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Authors: Georgina V. Long, E. Shklovskaya, L. Satgunaseelan, Yizhe Mao, I. D. da Silva, Kristen A Perry, R. Diefenbach, T. Gide, B. Shivalingam, Michael E Buckland, Maria Gonzalez, Nicole Caixeiro, I. A. Vergara, Xinyu Bai, R. Rawson, Edward Hsiao, U. Palendira, T. G. Phan, A. Menzies, Matteo S. Carlino, Camelia Quek, S. Grimmond, J. Vissers, D. Yeo, John E. J. Rasko, Mustafa Khasraw, B. Neyns, D. Reardon, David M. Ashley, Helen Wheeler, Michael Back, R. Scolyer, James Drummond, J. Wilmott, H. Rizos

Year: 2025

Venue: Nature Medicine

DOI: https://doi.org/10.1038/s41591-025-03512-1

Paper PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease.

Srinivasan, Priya, Wu, Xiaofang, Basu, Mousumi, Rossi, Christopher, Sandler, Anthony D · 2018 · PLoS medicine · DOI

Full title: PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease.

Authors: Srinivasan, Priya, Wu, Xiaofang, Basu, Mousumi, Rossi, Christopher, Sandler, Anthony D

Year: 2018

Venue: PLoS medicine

DOI: https://doi.org/10.1371/journal.pmed.1002497

Paper A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov.

Yang, Jing, Kang, Heming, Lyu, Liyang, Xiong, Wei, Hu, Yuanjia · 2023 · Discover oncology · DOI

Full title: A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov.

Authors: Yang, Jing, Kang, Heming, Lyu, Liyang, Xiong, Wei, Hu, Yuanjia

Year: 2023

Venue: Discover oncology

DOI: https://doi.org/10.1007/s12672-023-00758-4

Paper Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy.

Naito, Hirohito, Taoka, Rikiya, Zhang, Xia, Hossain, Akram, Abe, Yohei, Sugimoto, Mikio · 2025 · BMC immunology · DOI

Full title: Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy.

Authors: Naito, Hirohito, Taoka, Rikiya, Zhang, Xia, Hossain, Akram, Abe, Yohei, Sugimoto, Mikio

Year: 2025

Venue: BMC immunology

DOI: https://doi.org/10.1186/s12865-025-00751-2

Paper Immune checkpoint inhibitors: breakthroughs in cancer treatment.

Kong, Xueqing, Zhang, Jinyi, Chen, Shuwei, Wang, Xianyang, Xi, Qing, Shen, Han, Zhang, Rongxin · 2024 · Cancer biology & medicine · DOI

Full title: Immune checkpoint inhibitors: breakthroughs in cancer treatment.

Authors: Kong, Xueqing, Zhang, Jinyi, Chen, Shuwei, Wang, Xianyang, Xi, Qing, Shen, Han, Zhang, Rongxin

Year: 2024

Venue: Cancer biology & medicine

DOI: https://doi.org/10.20892/j.issn.2095-3941.2024.0055

Paper Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma.

Takenaka, Wataru, Takahashi, Yutaka, Tamari, Keisuke, Minami, Kazumasa, Katsuki, Shohei, Seo, Yuji, Isohashi, Fumiaki, Koizumi, Masahiko, Ogawa, Kazuhiko · 2020 · Cancers · DOI

Full title: Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma.

Authors: Takenaka, Wataru, Takahashi, Yutaka, Tamari, Keisuke, Minami, Kazumasa, Katsuki, Shohei, Seo, Yuji, Isohashi, Fumiaki, Koizumi, Masahiko, Ogawa, Kazuhiko

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12061546

Paper New therapeutics for soft tissue sarcomas: Overview of current immunotherapy and future directions of soft tissue sarcomas

Seong, Gyuhee, D’Angelo, Sandra P. · 2023 · Frontiers in Oncology · DOI

Full title: New therapeutics for soft tissue sarcomas: Overview of current immunotherapy and future directions of soft tissue sarcomas

Authors: Seong, Gyuhee, D’Angelo, Sandra P.

Year: 2023

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2023.1150765

Paper Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial.

Ray-Coquard, Isabelle, Kaminsky-Forrett, Marie-Christine, Ohkuma, Ryotaro, de Montfort, Aymeric, Joly, Florence, Treilleux, Isabelle, Ghamry-Barrin, Sarah, Bello-Roufai, Diana, Saintigny, Pierre, Angelergues, Antoine, Michon, Lucas, Hardy-Bessard, Anne-Claire, Attignon, Valéry, Auclair, Jessie, Chemin, Gabriel, Lainé, Alexandra, Péré, Hélène, Veyer, David, Savoye, Aude-Marie, Berthet, Justine, Caux, Christophe, Lecuru, Fabrice, Dubois, Bertrand, Bétrian, Sarah · 2026 · Nature communications · DOI

Full title: Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial.

Authors: Ray-Coquard, Isabelle, Kaminsky-Forrett, Marie-Christine, Ohkuma, Ryotaro, de Montfort, Aymeric, Joly, Florence, Treilleux, Isabelle, Ghamry-Barrin, Sarah, Bello-Roufai, Diana, Saintigny, Pierre, Angelergues, Antoine, Michon, Lucas, Hardy-Bessard, Anne-Claire, Attignon, Valéry, Auclair, Jessie, Chemin, Gabriel, Lainé, Alexandra, Péré, Hélène, Veyer, David, Savoye, Aude-Marie, Berthet, Justine, Caux, Christophe, Lecuru, Fabrice, Dubois, Bertrand, Bétrian, Sarah

Year: 2026

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-67646-z

Paper Immune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies.

Yang, Wenwen, Lei, Caining, Song, Shaoming, Jing, Wutang, Jin, Chuanwei, Gong, Shiyi, Tian, Hongwei, Guo, Tiankang · 2021 · Cancer cell international · DOI

Full title: Immune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies.

Authors: Yang, Wenwen, Lei, Caining, Song, Shaoming, Jing, Wutang, Jin, Chuanwei, Gong, Shiyi, Tian, Hongwei, Guo, Tiankang

Year: 2021

Venue: Cancer cell international

DOI: https://doi.org/10.1186/s12935-021-02299-8

Paper Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression

Dolina, Joseph S., Lee, Joey, Brightman, Spencer E., McArdle, Sara, Hall, Samantha, Thota, Rukman R., Zavala, Karla Soria, Lanka, Manasa, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason, Cohen, Ezra E.W., Peters, Bjoern, Schoenberger, Stephen P. · 2023 · Journal of Clinical Investigation · DOI

Full title: Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression

Authors: Dolina, Joseph S., Lee, Joey, Brightman, Spencer E., McArdle, Sara, Hall, Samantha, Thota, Rukman R., Zavala, Karla Soria, Lanka, Manasa, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason, Cohen, Ezra E.W., Peters, Bjoern, Schoenberger, Stephen P.

Year: 2023

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci164258

Paper Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Agioti, Stephanie, Zaravinos, Apostolos · 2024 · Preprints.org · DOI

Full title: Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Authors: Agioti, Stephanie, Zaravinos, Apostolos

Year: 2024

Venue: Preprints.org

DOI: https://doi.org/10.20944/preprints202401.2227.v1

Paper Current trends in glioblastoma multiforme treatment: radiation therapy and immune checkpoint inhibitors.

Nicholas, Sarah, Mathios, Dimitris, Ruzevick, Jacob, Jackson, Christopher, Yang, Isaac, Lim, Michael · 2013 · Brain tumor research and treatment · DOI

Full title: Current trends in glioblastoma multiforme treatment: radiation therapy and immune checkpoint inhibitors.

Authors: Nicholas, Sarah, Mathios, Dimitris, Ruzevick, Jacob, Jackson, Christopher, Yang, Isaac, Lim, Michael

Year: 2013

Venue: Brain tumor research and treatment

DOI: https://doi.org/10.14791/btrt.2013.1.1.2

Paper Unraveling Th subsets: insights into their role in immune checkpoint inhibitor therapy.

Ryba-Stanisławowska, Monika · 2025 · Cellular oncology (Dordrecht, Netherlands) · DOI

Full title: Unraveling Th subsets: insights into their role in immune checkpoint inhibitor therapy.

Authors: Ryba-Stanisławowska, Monika

Year: 2025

Venue: Cellular oncology (Dordrecht, Netherlands)

DOI: https://doi.org/10.1007/s13402-024-00992-0

Paper Risk of Cardiac Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-Analysis.

Hu, Jiexuan, Tian, Ruyue, Ma, Yingjie, Zhen, Hongchao, Ma, Xiao, Su, Qiang, Cao, Bangwei · 2021 · Frontiers in oncology · DOI

Full title: Risk of Cardiac Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-Analysis.

Authors: Hu, Jiexuan, Tian, Ruyue, Ma, Yingjie, Zhen, Hongchao, Ma, Xiao, Su, Qiang, Cao, Bangwei

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.645245

Paper [Immune-related adverse events of immune checkpoint inhibitors].

Tadano, Hiroki, Torigoe, Toshihiko · 2017 · Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology · DOI

Full title: [Immune-related adverse events of immune checkpoint inhibitors].

Authors: Tadano, Hiroki, Torigoe, Toshihiko

Year: 2017

Venue: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

DOI: https://doi.org/10.2177/jsci.40.102

Paper Immune Checkpoint Inhibitor Rechallenge in Renal Cell Carcinoma: Current Evidence and Future Directions

Sammarco, Enrico, Manfredi, Fiorella, Nuzzo, Amedeo, Ferrari, Marco, Bonato, Adele, Salfi, Alessia, Serafin, Debora, Zatteri, Luca, Antonuzzo, Andrea, Galli, Luca · 2023 · Cancers · DOI

Full title: Immune Checkpoint Inhibitor Rechallenge in Renal Cell Carcinoma: Current Evidence and Future Directions

Authors: Sammarco, Enrico, Manfredi, Fiorella, Nuzzo, Amedeo, Ferrari, Marco, Bonato, Adele, Salfi, Alessia, Serafin, Debora, Zatteri, Luca, Antonuzzo, Andrea, Galli, Luca

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15123172

Paper The Role of CTLA-4 in T Cell Exhaustion in Chronic Hepatitis B Virus Infection.

Apol, Ása Didriksen, Winckelmann, Anni Assing, Duus, Rasmus Bülow, Bukh, Jens, Weis, Nina · 2023 · Viruses · DOI

Full title: The Role of CTLA-4 in T Cell Exhaustion in Chronic Hepatitis B Virus Infection.

Authors: Apol, Ása Didriksen, Winckelmann, Anni Assing, Duus, Rasmus Bülow, Bukh, Jens, Weis, Nina

Year: 2023

Venue: Viruses

DOI: https://doi.org/10.3390/v15051141

Paper Overview of New Treatments with Immunotherapy for Breast Cancer and a Proposal of a Combination Therapy

Galván-Morales, Miguel Ángel, Rodríguez, Raúl Barrera, Santiago, Julio, Terán, Luis M. · 2020 · Molecules · DOI

Full title: Overview of New Treatments with Immunotherapy for Breast Cancer and a Proposal of a Combination Therapy

Authors: Galván-Morales, Miguel Ángel, Rodríguez, Raúl Barrera, Santiago, Julio, Terán, Luis M.

Year: 2020

Venue: Molecules

DOI: https://doi.org/10.3390/molecules25235686

Paper TIM-3 as a promising target for cancer immunotherapy in a wide range of tumors

Sauer, Natalia, Janicka, Natalia, Szlasa, Wojciech, Skinderowicz, Bartłomiej, Kołodzińska, Katarzyna, Dwernicka, Wioletta, Oślizło, Małgorzata, Kulbacka, Julita, Novickij, Vitalij, Karłowicz-Bodalska, Katarzyna · 2023 · Cancer Immunology Immunotherapy · DOI

Full title: TIM-3 as a promising target for cancer immunotherapy in a wide range of tumors

Authors: Sauer, Natalia, Janicka, Natalia, Szlasa, Wojciech, Skinderowicz, Bartłomiej, Kołodzińska, Katarzyna, Dwernicka, Wioletta, Oślizło, Małgorzata, Kulbacka, Julita, Novickij, Vitalij, Karłowicz-Bodalska, Katarzyna

Year: 2023

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-023-03516-1

Paper STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade.

Hannah Yang, W. Lee, S. Kong, C. Kim, Joo Hoon Kim, S. Chang, Sewha Kim, Gwangil Kim, H. Chon, Chan Kim · 2019 · Journal of Clinical Investigation · DOI

Full title: STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade.

Authors: Hannah Yang, W. Lee, S. Kong, C. Kim, Joo Hoon Kim, S. Chang, Sewha Kim, Gwangil Kim, H. Chon, Chan Kim

Year: 2019

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci125413

Paper Phase 1b Study of Tovorafenib, Plozalizumab or Vedolizumab Plus Standard-of-Care Immune Checkpoint Inhibitors in Patients with Advanced Melanoma.

Sullivan, Ryan J, Tsai, Katy K, Pavlick, Anna C, Buchbinder, Elizabeth I, Agarwala, Sanjiv S, Ribas, Antoni, Jansson, Johan, Rossiter, Guillermo, Olszanski, Anthony J · 2025 · Journal of Cancer · DOI

Full title: Phase 1b Study of Tovorafenib, Plozalizumab or Vedolizumab Plus Standard-of-Care Immune Checkpoint Inhibitors in Patients with Advanced Melanoma.

Authors: Sullivan, Ryan J, Tsai, Katy K, Pavlick, Anna C, Buchbinder, Elizabeth I, Agarwala, Sanjiv S, Ribas, Antoni, Jansson, Johan, Rossiter, Guillermo, Olszanski, Anthony J

Year: 2025

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.117878

Paper New dimensions of PD-1/PD-L1 inhibitor combination therapy in cancer treatment: current advances and future perspectives.

Tong, Cheng, Wu, Yue, Wu, Renzhao · 2025 · Frontiers in immunology · DOI

Full title: New dimensions of PD-1/PD-L1 inhibitor combination therapy in cancer treatment: current advances and future perspectives.

Authors: Tong, Cheng, Wu, Yue, Wu, Renzhao

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1616872

Paper Central Nervous System Demyelination Associated With Immune Checkpoint Inhibitors: Review of the Literature.

Oliveira, Marcos C B, de Brito, Marcelo H, Simabukuro, Mateus M · 2020 · Frontiers in neurology · DOI

Full title: Central Nervous System Demyelination Associated With Immune Checkpoint Inhibitors: Review of the Literature.

Authors: Oliveira, Marcos C B, de Brito, Marcelo H, Simabukuro, Mateus M

Year: 2020

Venue: Frontiers in neurology

DOI: https://doi.org/10.3389/fneur.2020.538695

Paper Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoint inhibition in the treatment of pediatric metastatic melanoma.

McCarty, Kyra L, Watt, Tanya, Dan, Tu D, Timmerman, Robert D, Kumar, Kiran A · 2025 · Radiation oncology (London, England) · DOI

Full title: Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoint inhibition in the treatment of pediatric metastatic melanoma.

Authors: McCarty, Kyra L, Watt, Tanya, Dan, Tu D, Timmerman, Robert D, Kumar, Kiran A

Year: 2025

Venue: Radiation oncology (London, England)

DOI: https://doi.org/10.1186/s13014-025-02691-y

Paper Recent advances in immune checkpoint inhibitors for non-small lung cancer treatment.

Altaf, Reem, Jadoon, Sarmad Sheraz, Muhammad, Syed Aun, Ilyas, Umair, Duan, Yongtao · 2022 · Frontiers in oncology · DOI

Full title: Recent advances in immune checkpoint inhibitors for non-small lung cancer treatment.

Authors: Altaf, Reem, Jadoon, Sarmad Sheraz, Muhammad, Syed Aun, Ilyas, Umair, Duan, Yongtao

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.1014156

Paper Immune checkpoint inhibitors therapy in older patients (≥ 70 years) with metastatic melanoma: a multicentre study.

Cybulska-Stopa, Bożena, Ługowska, Iwona, Jagodzińska-Mucha, Paulina, Koseła-Paterczyk, Hanna, Kozak, Katarzyna, Klimczak, Anna, Świtaj, Tomasz, Ziobro, Marek, Roman, Agnieszka, Rajczykowski, Marcin, Suwiński, Rafał, Niemiec, Maciej, Zemełka, Tomasz, Falkowski, Sławomir, Rutkowski, Piotr · 2019 · Postepy dermatologii i alergologii · DOI

Full title: Immune checkpoint inhibitors therapy in older patients (≥ 70 years) with metastatic melanoma: a multicentre study.

Authors: Cybulska-Stopa, Bożena, Ługowska, Iwona, Jagodzińska-Mucha, Paulina, Koseła-Paterczyk, Hanna, Kozak, Katarzyna, Klimczak, Anna, Świtaj, Tomasz, Ziobro, Marek, Roman, Agnieszka, Rajczykowski, Marcin, Suwiński, Rafał, Niemiec, Maciej, Zemełka, Tomasz, Falkowski, Sławomir, Rutkowski, Piotr

Year: 2019

Venue: Postepy dermatologii i alergologii

DOI: https://doi.org/10.5114/ada.2018.79940

Paper BRAF inhibitors: resistance and the promise of combination treatments for melanoma.

Griffin, Merope, Scotto, Daniele, Josephs, Debra H, Mele, Silvia, Crescioli, Silvia, Bax, Heather J, Pellizzari, Giulia, Wynne, Matthew D, Nakamura, Mano, Hoffmann, Ricarda M, Ilieva, Kristina M, Cheung, Anthony, Spicer, James F, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N · 2017 · Oncotarget · DOI

Full title: BRAF inhibitors: resistance and the promise of combination treatments for melanoma.

Authors: Griffin, Merope, Scotto, Daniele, Josephs, Debra H, Mele, Silvia, Crescioli, Silvia, Bax, Heather J, Pellizzari, Giulia, Wynne, Matthew D, Nakamura, Mano, Hoffmann, Ricarda M, Ilieva, Kristina M, Cheung, Anthony, Spicer, James F, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.19836

Paper Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer.

Jama, Maryam, Tabana, Yasser, Barakat, Khaled H · 2024 · European journal of medical research · DOI

Full title: Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer.

Authors: Jama, Maryam, Tabana, Yasser, Barakat, Khaled H

Year: 2024

Venue: European journal of medical research

DOI: https://doi.org/10.1186/s40001-024-01901-9

Paper Merkel Cell Carcinoma-Update on Diagnosis, Management and Future Perspectives.

Zaggana, Eleni, Konstantinou, Maria Polina, Krasagakis, Gregor Herrmann, de Bree, Eelco, Kalpakis, Konstantinos, Mavroudis, Dimitrios, Krasagakis, Konstantinos · 2022 · Cancers · DOI

Full title: Merkel Cell Carcinoma-Update on Diagnosis, Management and Future Perspectives.

Authors: Zaggana, Eleni, Konstantinou, Maria Polina, Krasagakis, Gregor Herrmann, de Bree, Eelco, Kalpakis, Konstantinos, Mavroudis, Dimitrios, Krasagakis, Konstantinos

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15010103

Paper Immunotherapy for Melanoma: The Significance of Immune Checkpoint Inhibitors for the Treatment of Advanced Melanoma.

Fujimura, Taku, Muto, Yusuke, Asano, Yoshihide · 2022 · International journal of molecular sciences · DOI

Full title: Immunotherapy for Melanoma: The Significance of Immune Checkpoint Inhibitors for the Treatment of Advanced Melanoma.

Authors: Fujimura, Taku, Muto, Yusuke, Asano, Yoshihide

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232415720

Paper Cancer immunotherapy: the beginning of the end of cancer?

Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M. · 2016 · BMC Medicine · DOI

Full title: Cancer immunotherapy: the beginning of the end of cancer?

Authors: Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M.

Year: 2016

Venue: BMC Medicine

DOI: https://doi.org/10.1186/s12916-016-0623-5

Paper Immune Checkpoints and Innovative Therapies in Glioblastoma.

Romani, Massimo, Pistillo, Maria Pia, Carosio, Roberta, Morabito, Anna, Banelli, Barbara · 2018 · Frontiers in oncology · DOI

Full title: Immune Checkpoints and Innovative Therapies in Glioblastoma.

Authors: Romani, Massimo, Pistillo, Maria Pia, Carosio, Roberta, Morabito, Anna, Banelli, Barbara

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00464

Paper Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?

Jatoi, Ismail, Benson, John R., Kunkler, Ian · 2018 · npj Breast Cancer · DOI

Full title: Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?

Authors: Jatoi, Ismail, Benson, John R., Kunkler, Ian

Year: 2018

Venue: npj Breast Cancer

DOI: https://doi.org/10.1038/s41523-018-0061-y

Paper Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity.

Narikawa, Yoichiro, Kuramasu, Atsuo, Hosonuma, Masahiro, Murayama, Masakazu, Funayama, Eiji, Sasaki, Akiko, Baba, Yuta, Toyoda, Hitoshi, Isobe, Junya, Tajima, Kohei, Nakashima, Rie, Sasaki, Aya, Maruyama, Yuki, Yamazaki, Yoshitaka, Shida, Midori, Tsurui, Toshiaki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Horiike, Atsushi, Kobayashi, Shinichi, Tsunoda, Takuya, Kobayashi, Sei, Kobayashi, Hitome, Oguchi, Tatsunori, Shimane, Toshikazu, Kiuchi, Yuji, Yoshimura, Kiyoshi · 2025 · Cancer immunology, immunotherapy : CII · DOI

Full title: Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity.

Authors: Narikawa, Yoichiro, Kuramasu, Atsuo, Hosonuma, Masahiro, Murayama, Masakazu, Funayama, Eiji, Sasaki, Akiko, Baba, Yuta, Toyoda, Hitoshi, Isobe, Junya, Tajima, Kohei, Nakashima, Rie, Sasaki, Aya, Maruyama, Yuki, Yamazaki, Yoshitaka, Shida, Midori, Tsurui, Toshiaki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Horiike, Atsushi, Kobayashi, Shinichi, Tsunoda, Takuya, Kobayashi, Sei, Kobayashi, Hitome, Oguchi, Tatsunori, Shimane, Toshikazu, Kiuchi, Yuji, Yoshimura, Kiyoshi

Year: 2025

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-025-04111-2

Paper Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.

Goswami, Sangeeta, Apostolou, Irina, Zhang, Jan, Skepner, Jill, Anandhan, Swetha, Zhang, Xuejun, Xiong, Liangwen, Trojer, Patrick, Aparicio, Ana, Subudhi, Sumit K, Allison, James P, Zhao, Hao, Sharma, Padmanee · 2018 · The Journal of clinical investigation · DOI

Full title: Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.

Authors: Goswami, Sangeeta, Apostolou, Irina, Zhang, Jan, Skepner, Jill, Anandhan, Swetha, Zhang, Xuejun, Xiong, Liangwen, Trojer, Patrick, Aparicio, Ana, Subudhi, Sumit K, Allison, James P, Zhao, Hao, Sharma, Padmanee

Year: 2018

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI99760

Paper Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer.

Zhang, Hao, Dai, Ziyu, Wu, Wantao, Wang, Zeyu, Zhang, Nan, Zhang, Liyang, Zeng, Wen-Jing, Liu, Zhixiong, Cheng, Quan · 2021 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer.

Authors: Zhang, Hao, Dai, Ziyu, Wu, Wantao, Wang, Zeyu, Zhang, Nan, Zhang, Liyang, Zeng, Wen-Jing, Liu, Zhixiong, Cheng, Quan

Year: 2021

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-021-01987-7

Paper Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation.

Xu, Xiaoyan, Xie, Tingxue, Zhou, Mengxin, Sun, Yaqin, Wang, Fengqi, Tian, Yanan, Chen, Ziyan, Xie, Yanqi, Wu, Ronghai, Cen, Xufeng, Zhou, Jichun, Hou, Tingjun, Zhang, Lei, Huang, Chaoyang, Zhao, Qingwei, Wang, Dongrui, Xia, Hongguang · 2024 · Nature communications · DOI

Full title: Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation.

Authors: Xu, Xiaoyan, Xie, Tingxue, Zhou, Mengxin, Sun, Yaqin, Wang, Fengqi, Tian, Yanan, Chen, Ziyan, Xie, Yanqi, Wu, Ronghai, Cen, Xufeng, Zhou, Jichun, Hou, Tingjun, Zhang, Lei, Huang, Chaoyang, Zhao, Qingwei, Wang, Dongrui, Xia, Hongguang

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-48597-3

Paper Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

Ascierto, Paolo A., Puzanov, Igor, Agarwala, Sanjiv S., Bifulco, Carlo, Botti, Gerardo, Caracò, Corrado, Ciliberto, Gennaro, Davies, Michael A., Dummer, Reinhard, Ferrone, Soldano, Gajewski, Thomas F., Garbe, Claus, Luke, Jason J., Marincola, Francesco M., Masucci, Giuseppe, Mehnert, Janice M., Mozzillo, N, Palmieri, Giuseppe, Postow, Michael A., Schoenberger, Stephen P., Wang, Ena, Hu, Hong‐Ming · 2018 · Journal of Translational Medicine · DOI

Full title: Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

Authors: Ascierto, Paolo A., Puzanov, Igor, Agarwala, Sanjiv S., Bifulco, Carlo, Botti, Gerardo, Caracò, Corrado, Ciliberto, Gennaro, Davies, Michael A., Dummer, Reinhard, Ferrone, Soldano, Gajewski, Thomas F., Garbe, Claus, Luke, Jason J., Marincola, Francesco M., Masucci, Giuseppe, Mehnert, Janice M., Mozzillo, N, Palmieri, Giuseppe, Postow, Michael A., Schoenberger, Stephen P., Wang, Ena, Hu, Hong‐Ming

Year: 2018

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-018-1568-6

Paper Potential role of immunotherapy in advanced non-small-cell lung cancer.

de Mello, Ramon Andrade, Veloso, Ana Flávia, Esrom Catarina, Paulo, Nadine, Sara, Antoniou, Georgios · 2017 · OncoTargets and therapy · DOI

Full title: Potential role of immunotherapy in advanced non-small-cell lung cancer.

Authors: de Mello, Ramon Andrade, Veloso, Ana Flávia, Esrom Catarina, Paulo, Nadine, Sara, Antoniou, Georgios

Year: 2017

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S90459

Paper Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II-III breast cancer.

Garber, Haven R, Basu, Sreyashi, Jindal, Sonali, He, Zhong, Chu, Khoi, Raghavendra, Akshara Singareeka, Yam, Clinton, Santiago, Lumarie, Adrada, Beatriz E, Sharma, Padmanee, Mittendorf, Elizabeth A, Litton, Jennifer K · 2024 · Oncotarget · DOI

Full title: Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II-III breast cancer.

Authors: Garber, Haven R, Basu, Sreyashi, Jindal, Sonali, He, Zhong, Chu, Khoi, Raghavendra, Akshara Singareeka, Yam, Clinton, Santiago, Lumarie, Adrada, Beatriz E, Sharma, Padmanee, Mittendorf, Elizabeth A, Litton, Jennifer K

Year: 2024

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.28567

Paper Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system.

Wang, Feifei, Wei, Qi, Wu, Xinan · 2022 · Frontiers in pharmacology · DOI

Full title: Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system.

Authors: Wang, Feifei, Wei, Qi, Wu, Xinan

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.986357

Paper Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC

Luo, Yuejun, Sun, Nan, He, Jie · 2022 · Signal Transduction and Targeted Therapy · DOI

Full title: Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC

Authors: Luo, Yuejun, Sun, Nan, He, Jie

Year: 2022

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-022-01022-x

Paper [Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

Iwata, Tomomi Nakayama, Sugihara, Kiyoshi, Wada, Teiji, Agatsuma, Toshinori · 2019 · PloS one · DOI

Full title: [Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

Authors: Iwata, Tomomi Nakayama, Sugihara, Kiyoshi, Wada, Teiji, Agatsuma, Toshinori

Year: 2019

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0222280

Paper Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities.

Yin, Nanhao, Li, Xintong, Zhang, Xuanwei, Xue, Shaolong, Cao, Yu, Niedermann, Gabriele, Lu, You, Xue, Jianxin · 2024 · Signal transduction and targeted therapy · DOI

Full title: Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities.

Authors: Yin, Nanhao, Li, Xintong, Zhang, Xuanwei, Xue, Shaolong, Cao, Yu, Niedermann, Gabriele, Lu, You, Xue, Jianxin

Year: 2024

Venue: Signal transduction and targeted therapy

DOI: https://doi.org/10.1038/s41392-024-01826-z

Paper The Future of Checkpoint Inhibitors in Uveal Melanoma: A Narrative Review.

Wang, Jinyu, Li, Zehua, Yin, Hongbo · 2024 · Ophthalmology and therapy · DOI

Full title: The Future of Checkpoint Inhibitors in Uveal Melanoma: A Narrative Review.

Authors: Wang, Jinyu, Li, Zehua, Yin, Hongbo

Year: 2024

Venue: Ophthalmology and therapy

DOI: https://doi.org/10.1007/s40123-024-00913-2

Paper Nivolumab and Ipilimumab Acting as Tormentors of Advanced Tumors by Unleashing Immune Cells and Associated Collateral Damage.

Khan, Bushra, Qahwaji, Rowaid M, Alfaifi, Mashael S, Mobashir, Mohammad · 2024 · Pharmaceutics · DOI

Full title: Nivolumab and Ipilimumab Acting as Tormentors of Advanced Tumors by Unleashing Immune Cells and Associated Collateral Damage.

Authors: Khan, Bushra, Qahwaji, Rowaid M, Alfaifi, Mashael S, Mobashir, Mohammad

Year: 2024

Venue: Pharmaceutics

DOI: https://doi.org/10.3390/pharmaceutics16060732

Paper NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.

Yoshihama, Sayuri, Cho, Steven X, Yeung, Jason, Pan, Xuedong, Lizee, Gregory, Konganti, Kranti, Johnson, Valen E, Kobayashi, Koichi S · 2021 · Scientific reports · DOI

Full title: NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.

Authors: Yoshihama, Sayuri, Cho, Steven X, Yeung, Jason, Pan, Xuedong, Lizee, Gregory, Konganti, Kranti, Johnson, Valen E, Kobayashi, Koichi S

Year: 2021

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-021-82729-9

Paper Thyroid Storm and Type 1 Diabetes Mellitus Induced by Combined Ipilimumab and Nivolumab Immunotherapy: A Case Report.

Ramburuth, Vivek, Rajkanna, Jeyanthy · 2023 · Cureus · DOI

Full title: Thyroid Storm and Type 1 Diabetes Mellitus Induced by Combined Ipilimumab and Nivolumab Immunotherapy: A Case Report.

Authors: Ramburuth, Vivek, Rajkanna, Jeyanthy

Year: 2023

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.46985

Paper Immunotherapy of melanoma.

Lugowska, Iwona, Teterycz, Pawel, Rutkowski, Piotr · 2018 · Contemporary oncology (Poznan, Poland) · DOI

Full title: Immunotherapy of melanoma.

Authors: Lugowska, Iwona, Teterycz, Pawel, Rutkowski, Piotr

Year: 2018

Venue: Contemporary oncology (Poznan, Poland)

DOI: https://doi.org/10.5114/wo.2018.73889

Paper The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.

Renouf, Daniel J, Loree, Jonathan M, Knox, Jennifer J, Topham, James T, Kavan, Petr, Jonker, Derek, Welch, Stephen, Couture, Felix, Lemay, Frederic, Tehfe, Mustapha, Harb, Mohammed, Aucoin, Nathalie, Ko, Yoo-Joung, Tang, Patricia A, Ramjeesingh, Ravi, Meyers, Brandon M, Kim, Christina A, Du, Pan, Jia, Shidong, Schaeffer, David F, Gill, Sharlene, Tu, Dongsheng, O'Callaghan, Chris J · 2022 · Nature communications · DOI

Full title: The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.

Authors: Renouf, Daniel J, Loree, Jonathan M, Knox, Jennifer J, Topham, James T, Kavan, Petr, Jonker, Derek, Welch, Stephen, Couture, Felix, Lemay, Frederic, Tehfe, Mustapha, Harb, Mohammed, Aucoin, Nathalie, Ko, Yoo-Joung, Tang, Patricia A, Ramjeesingh, Ravi, Meyers, Brandon M, Kim, Christina A, Du, Pan, Jia, Shidong, Schaeffer, David F, Gill, Sharlene, Tu, Dongsheng, O'Callaghan, Chris J

Year: 2022

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-022-32591-8

Paper Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma.

Lee, Kyeongmi, Cha, Honghui, Kim, Jaewon, Jang, Yeongjun, Son, Yelin, Joe, Cheol Yong, Kim, Jaesang, Kim, Jhingook, Lee, Se-Hoon, Lee, Sanghyuk · 2024 · Scientific reports · DOI

Full title: Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma.

Authors: Lee, Kyeongmi, Cha, Honghui, Kim, Jaewon, Jang, Yeongjun, Son, Yelin, Joe, Cheol Yong, Kim, Jaesang, Kim, Jhingook, Lee, Se-Hoon, Lee, Sanghyuk

Year: 2024

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-024-72108-5

Paper Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors

Ouyang, Peng, Wang, Lijuan, Wu, Jianlong, Tian, Yao, Chen, Caiyun, Li, Dengsheng, Yao, Zengxi, Chen, Ruichang, Xiang, Guoan, Gong, Jin, Bao, Zhen · 2024 · Frontiers in Immunology · DOI

Full title: Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors

Authors: Ouyang, Peng, Wang, Lijuan, Wu, Jianlong, Tian, Yao, Chen, Caiyun, Li, Dengsheng, Yao, Zengxi, Chen, Ruichang, Xiang, Guoan, Gong, Jin, Bao, Zhen

Year: 2024

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2024.1344272

Paper Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.

Shi, Lewis Zhichang, Fu, Tihui, Guan, Baoxiang, Chen, Jianfeng, Blando, Jorge M, Allison, James P, Xiong, Liangwen, Subudhi, Sumit K, Gao, Jianjun, Sharma, Padmanee · 2016 · Nature communications · DOI

Full title: Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.

Authors: Shi, Lewis Zhichang, Fu, Tihui, Guan, Baoxiang, Chen, Jianfeng, Blando, Jorge M, Allison, James P, Xiong, Liangwen, Subudhi, Sumit K, Gao, Jianjun, Sharma, Padmanee

Year: 2016

Venue: Nature communications

DOI: https://doi.org/10.1038/ncomms12335

Paper Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect

Boegeholz, Jan, Brueggen, C. S., Pauli, Chantal, Dimitriou, Florentia, Haralambieva, Eugenia, Dummer, Reinhard, Manz, Markus G., Widmer, Corinne C. · 2020 · BMC Cancer · DOI

Full title: Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect

Authors: Boegeholz, Jan, Brueggen, C. S., Pauli, Chantal, Dimitriou, Florentia, Haralambieva, Eugenia, Dummer, Reinhard, Manz, Markus G., Widmer, Corinne C.

Year: 2020

Venue: BMC Cancer

DOI: https://doi.org/10.1186/s12885-020-06763-y

Paper Comparison of Efficacy and Safety of Single and Double Immune Checkpoint Inhibitor-Based First-Line Treatments for Advanced Driver-Gene Wild-Type Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.

Xu, Qian, Zhang, Xue, Huang, Miao, Dai, Xin, Gao, Jing, Li, Song, Sheng, Lei, Huang, Kai, Wang, Jian, Liu, Lian · 2021 · Frontiers in immunology · DOI

Full title: Comparison of Efficacy and Safety of Single and Double Immune Checkpoint Inhibitor-Based First-Line Treatments for Advanced Driver-Gene Wild-Type Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.

Authors: Xu, Qian, Zhang, Xue, Huang, Miao, Dai, Xin, Gao, Jing, Li, Song, Sheng, Lei, Huang, Kai, Wang, Jian, Liu, Lian

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.731546

Paper Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors.

Rapoport, Bernardo Leon · 2019 · Frontiers in oncology · DOI

Full title: Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors.

Authors: Rapoport, Bernardo Leon

Year: 2019

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2019.00365

Paper Anti-CTLA-4 Antibody Might Be Effective Against Non-small Cell Lung Cancer With Large Size Tumor.

Saijo, Hiroshi, Hirohashi, Yoshihiko, Honjo, Osamu, Saikai, Toyohiro, Shijubo, Naoki, Takabatake, Hirotsugu, Fujita, Akihisa, Honda, Yasuhito, Koba, Hiroyuki, Chiba, Hirofumi, Torigoe, Toshihiko · 2023 · Anticancer research · DOI

Full title: Anti-CTLA-4 Antibody Might Be Effective Against Non-small Cell Lung Cancer With Large Size Tumor.

Authors: Saijo, Hiroshi, Hirohashi, Yoshihiko, Honjo, Osamu, Saikai, Toyohiro, Shijubo, Naoki, Takabatake, Hirotsugu, Fujita, Akihisa, Honda, Yasuhito, Koba, Hiroyuki, Chiba, Hirofumi, Torigoe, Toshihiko

Year: 2023

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.16606

Paper Shiny-MAGEC: A Bayesian R shiny application for meta-analysis of censored adverse events

Zihan Zhou, Zizhong Tian, C. Peterson, Le Bao, Shouhao Zhou · 2025 · Research Synthesis Methods · DOI

Full title: Shiny-MAGEC: A Bayesian R shiny application for meta-analysis of censored adverse events

Authors: Zihan Zhou, Zizhong Tian, C. Peterson, Le Bao, Shouhao Zhou

Year: 2025

Venue: Research Synthesis Methods

DOI: https://doi.org/10.1017/rsm.2025.10052

Paper Emerging Targets in Clear Cell Renal Cell Carcinoma.

Chen, Yu-Wei, Rini, Brian I, Beckermann, Kathryn E · 2022 · Cancers · DOI

Full title: Emerging Targets in Clear Cell Renal Cell Carcinoma.

Authors: Chen, Yu-Wei, Rini, Brian I, Beckermann, Kathryn E

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14194843

Paper A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better

Djureinovic, Dijana, Weiss, Sarah A., Krykbaeva, Irina, Qu, Rihao, Vathiotis, Ioannis, Moutafi, Myrto, Zhang, Lin, Perdigoto, Ana Luisa, Wei, Wei, Anderson, Gail D., Damsky, William, Hurwitz, Michael E., Johnson, Barbara, Schoenfeld, David A., Mahajan, Amit, Hsu, Frank J., Miller‐Jensen, Kathryn, Kluger, Yuval, Sznol, Mario, Kaech, Susan M., Bosenberg, Marcus, Jilaveanu, Lucia B., Kluger, Harriet M. · 2023 · Molecular Cancer · DOI

Full title: A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better

Authors: Djureinovic, Dijana, Weiss, Sarah A., Krykbaeva, Irina, Qu, Rihao, Vathiotis, Ioannis, Moutafi, Myrto, Zhang, Lin, Perdigoto, Ana Luisa, Wei, Wei, Anderson, Gail D., Damsky, William, Hurwitz, Michael E., Johnson, Barbara, Schoenfeld, David A., Mahajan, Amit, Hsu, Frank J., Miller‐Jensen, Kathryn, Kluger, Yuval, Sznol, Mario, Kaech, Susan M., Bosenberg, Marcus, Jilaveanu, Lucia B., Kluger, Harriet M.

Year: 2023

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-023-01884-x

Paper Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma.

Zeng, Zhu, Yang, Biao, Liao, Zheng-Yin · 2020 · Oncology letters · DOI

Full title: Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma.

Authors: Zeng, Zhu, Yang, Biao, Liao, Zheng-Yin

Year: 2020

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2020.11909

Paper A Case of Immune-Mediated Pneumonitis Associated With Dual Nivolumab and Ipilimumab Immunotherapy Treatment.

Al-Saghir, Tala, Suleiman, Noor, Goodman, Benjamin D, Ferguson, Michael W, Tejwani, Sheela · 2023 · Cureus · DOI

Full title: A Case of Immune-Mediated Pneumonitis Associated With Dual Nivolumab and Ipilimumab Immunotherapy Treatment.

Authors: Al-Saghir, Tala, Suleiman, Noor, Goodman, Benjamin D, Ferguson, Michael W, Tejwani, Sheela

Year: 2023

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.40792

Paper A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.

Cao, Weian, Chen, Junfan, Fu, Yutong, Jiang, Haitao, Gao, Yu, Huang, Huiming, Fu, Yang-Xin, Wang, Wenyan · 2025 · Nature communications · DOI

Full title: A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.

Authors: Cao, Weian, Chen, Junfan, Fu, Yutong, Jiang, Haitao, Gao, Yu, Huang, Huiming, Fu, Yang-Xin, Wang, Wenyan

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-64081-y

Paper Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.

Usta, Sena Zeynep, Uchihashi, Toshihiro, Kodama, Shingo, Kurioka, Kyoko, Inubushi, Toshihiro, Shimooka, Takuya, Sugauchi, Akinari, Seki, Soju, Tanaka, Susumu · 2023 · International journal of molecular sciences · DOI

Full title: Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.

Authors: Usta, Sena Zeynep, Uchihashi, Toshihiro, Kodama, Shingo, Kurioka, Kyoko, Inubushi, Toshihiro, Shimooka, Takuya, Sugauchi, Akinari, Seki, Soju, Tanaka, Susumu

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms242417282

Paper Targeting immune checkpoints in malignant glioma.

Zhang, Xuhao, Zhu, Shan, Li, Tete, Liu, Yong-Jun, Chen, Wei, Chen, Jingtao · 2017 · Oncotarget · DOI

Full title: Targeting immune checkpoints in malignant glioma.

Authors: Zhang, Xuhao, Zhu, Shan, Li, Tete, Liu, Yong-Jun, Chen, Wei, Chen, Jingtao

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.12702

Paper Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.

Jo, Wonyoung, Won, Taejoon, Daoud, Abdel, Čiháková, Daniela · 2024 · Frontiers in immunology · DOI

Full title: Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.

Authors: Jo, Wonyoung, Won, Taejoon, Daoud, Abdel, Čiháková, Daniela

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1340373

Paper Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.

Peighambari, Asin, Huang, Hsin, Metzger, Patrick, Adlesic, Mojca, Zodel, Kyra, Schäfer, Silvia, Seidel, Philipp, Braun, Lukas M, Hülsdünker, Jan, Melchinger, Wolfgang, Follo, Marie, Ku, Manching, Haug, Stefan, Li, Yong, Köttgen, Anna, Schell, Christoph, von Elverfeldt, Dominik, Reichardt, Wilfried, Zeiser, Robert, Heikenwalder, Mathias, Höfflin, Rouven, Börries, Melanie, Frew, Ian J · 2025 · Scientific reports · DOI

Full title: Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.

Authors: Peighambari, Asin, Huang, Hsin, Metzger, Patrick, Adlesic, Mojca, Zodel, Kyra, Schäfer, Silvia, Seidel, Philipp, Braun, Lukas M, Hülsdünker, Jan, Melchinger, Wolfgang, Follo, Marie, Ku, Manching, Haug, Stefan, Li, Yong, Köttgen, Anna, Schell, Christoph, von Elverfeldt, Dominik, Reichardt, Wilfried, Zeiser, Robert, Heikenwalder, Mathias, Höfflin, Rouven, Börries, Melanie, Frew, Ian J

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-04917-1

Paper Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A, Lloyd, Christopher, Dovedi, Simon J, Sansom, David M · 2022 · Frontiers in immunology · DOI

Full title: Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

Authors: Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A, Lloyd, Christopher, Dovedi, Simon J, Sansom, David M

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.871802

Paper S100B and LDH as early prognostic markers for response and overall survival in melanoma patients treated with anti-PD-1 or combined anti-PD-1 plus anti-CTLA-4 antibodies.

Wagner, Nikolaus B, Forschner, Andrea, Leiter, Ulrike, Garbe, Claus, Eigentler, Thomas K · 2018 · British journal of cancer · DOI

Full title: S100B and LDH as early prognostic markers for response and overall survival in melanoma patients treated with anti-PD-1 or combined anti-PD-1 plus anti-CTLA-4 antibodies.

Authors: Wagner, Nikolaus B, Forschner, Andrea, Leiter, Ulrike, Garbe, Claus, Eigentler, Thomas K

Year: 2018

Venue: British journal of cancer

DOI: https://doi.org/10.1038/s41416-018-0167-x

Paper Limitations and potential of immunotherapy in ovarian cancer

Kumar, Sandeep, Acharya, Sayanti, Karthikeyan, Mahalakshmi, Biswas, Priyobrata, Kumari, Sudha · 2024 · Frontiers in Immunology · DOI

Full title: Limitations and potential of immunotherapy in ovarian cancer

Authors: Kumar, Sandeep, Acharya, Sayanti, Karthikeyan, Mahalakshmi, Biswas, Priyobrata, Kumari, Sudha

Year: 2024

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1292166

Paper PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.

Hirsch, Laure, Zitvogel, Laurence, Eggermont, Alexander, Marabelle, Aurelien · 2019 · British journal of cancer · DOI

Full title: PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.

Authors: Hirsch, Laure, Zitvogel, Laurence, Eggermont, Alexander, Marabelle, Aurelien

Year: 2019

Venue: British journal of cancer

DOI: https://doi.org/10.1038/s41416-018-0294-4

Paper Immune Dysregulation in Cancer Patients Undergoing Immune Checkpoint Inhibitor Treatment and Potential Predictive Strategies for Future Clinical Practice.

Anderson, Ronald, Rapoport, Bernardo L · 2018 · Frontiers in oncology · DOI

Full title: Immune Dysregulation in Cancer Patients Undergoing Immune Checkpoint Inhibitor Treatment and Potential Predictive Strategies for Future Clinical Practice.

Authors: Anderson, Ronald, Rapoport, Bernardo L

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00080

Paper Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy.

Lyu, Jiacheng, Bai, Lin, Li, Yumiao, Wang, Xiaofang, Xu, Zeya, Ji, Tao, Yang, Hua, Song, Zizheng, Wang, Zhiyu, Shang, Yanhong, Ren, Lili, Li, Yan, Zang, Aimin, Jia, Youchao, Ding, Chen · 2024 · Nature communications · DOI

Full title: Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy.

Authors: Lyu, Jiacheng, Bai, Lin, Li, Yumiao, Wang, Xiaofang, Xu, Zeya, Ji, Tao, Yang, Hua, Song, Zizheng, Wang, Zhiyu, Shang, Yanhong, Ren, Lili, Li, Yan, Zang, Aimin, Jia, Youchao, Ding, Chen

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-47835-y

Paper Tumor immunophenotyping-derived signature identifies prognosis and neoadjuvant immunotherapeutic responsiveness in gastric cancer

Wang, Jia-Bin, Qiu, Qing-Zhu, Zheng, Qiaoling, Zhao, Yajun, Xu, Yü, Zhang, Tao, Wang, Shuanhu, Wang, Quan, Jin, Qinwen, Ye, Yin‐Hua, Li, Ping, Xie, Jian-Wei, Lin, Jian‐Xian, Lu, Jun, Chen, Qi‐Yue, Cao, Long‐Long, Yang, Yinghong, Zheng, Chao‐Hui, Huang, Chang‐Ming · 2022 · Research Square (Research Square) · DOI

Full title: Tumor immunophenotyping-derived signature identifies prognosis and neoadjuvant immunotherapeutic responsiveness in gastric cancer

Authors: Wang, Jia-Bin, Qiu, Qing-Zhu, Zheng, Qiaoling, Zhao, Yajun, Xu, Yü, Zhang, Tao, Wang, Shuanhu, Wang, Quan, Jin, Qinwen, Ye, Yin‐Hua, Li, Ping, Xie, Jian-Wei, Lin, Jian‐Xian, Lu, Jun, Chen, Qi‐Yue, Cao, Long‐Long, Yang, Yinghong, Zheng, Chao‐Hui, Huang, Chang‐Ming

Year: 2022

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-2248043/v1

Paper Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma.

Low, Samantha Su Ping, El-Shakankery, Karim, Brown, Ewan, Christie, Alan, McCormack, Sally, Stares, Mark · 2024 · Frontiers in oncology · DOI

Full title: Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma.

Authors: Low, Samantha Su Ping, El-Shakankery, Karim, Brown, Ewan, Christie, Alan, McCormack, Sally, Stares, Mark

Year: 2024

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2024.1330271

Paper LAG3 immune inhibitors: a novel strategy for melanoma treatment.

Wu, Renzheng, Zeng, Mingtang, Zhang, Yuchen, He, Jianping · 2024 · Frontiers in oncology · DOI

Full title: LAG3 immune inhibitors: a novel strategy for melanoma treatment.

Authors: Wu, Renzheng, Zeng, Mingtang, Zhang, Yuchen, He, Jianping

Year: 2024

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2024.1514578

Paper Cutaneous Adverse Events Associated with Immune Checkpoint Inhibitors: A Review Article.

Chen, Chieh-Hsun, Yu, Hsin-Su, Yu, Sebastian · 2022 · Current oncology (Toronto, Ont.) · DOI

Full title: Cutaneous Adverse Events Associated with Immune Checkpoint Inhibitors: A Review Article.

Authors: Chen, Chieh-Hsun, Yu, Hsin-Su, Yu, Sebastian

Year: 2022

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3390/curroncol29040234

Paper Metabolic and Nutritional Disorders Following the Administration of Immune Checkpoint Inhibitors: A Pharmacovigilance Study.

Zhai, Yinghong, Ye, Xiaofei, Hu, Fangyuan, Xu, Jinfang, Guo, Xiaojing, Zhou, Xiang, Zheng, Yi, Zhao, Xinxin, Xu, Xiao, Cao, Yang, He, Jia · 2021 · Frontiers in endocrinology · DOI

Full title: Metabolic and Nutritional Disorders Following the Administration of Immune Checkpoint Inhibitors: A Pharmacovigilance Study.

Authors: Zhai, Yinghong, Ye, Xiaofei, Hu, Fangyuan, Xu, Jinfang, Guo, Xiaojing, Zhou, Xiang, Zheng, Yi, Zhao, Xinxin, Xu, Xiao, Cao, Yang, He, Jia

Year: 2021

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2021.809063

Paper Mucocutaneous adverse events to immune checkpoint inhibitors.

Muhaj, Fiorinda, Karri, Padmavathi V, Moody, Wylie, Brown, Alexandria, Patel, Anisha B · 2023 · Frontiers in allergy · DOI

Full title: Mucocutaneous adverse events to immune checkpoint inhibitors.

Authors: Muhaj, Fiorinda, Karri, Padmavathi V, Moody, Wylie, Brown, Alexandria, Patel, Anisha B

Year: 2023

Venue: Frontiers in allergy

DOI: https://doi.org/10.3389/falgy.2023.1147513

Paper Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

Y. Saida, J. Brender, Kazu Yamamoto, James B. Mitchell, M. Krishna, S. Kishimoto · 2020 · bioRxiv · DOI

Full title: Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

Authors: Y. Saida, J. Brender, Kazu Yamamoto, James B. Mitchell, M. Krishna, S. Kishimoto

Year: 2020

Venue: bioRxiv

DOI: https://doi.org/10.1101/2020.04.30.070508

Paper Current Landscape of Immune Checkpoint Inhibitors for Metastatic Urothelial Carcinoma: Is There a Role for Additional T-Cell Blockade?

Ogbuji, Vanessa, Paster, Irasema C, Recio-Boiles, Alejandro, Carew, Jennifer S, Nawrocki, Steffan T, Chipollini, Juan · 2023 · Cancers · DOI

Full title: Current Landscape of Immune Checkpoint Inhibitors for Metastatic Urothelial Carcinoma: Is There a Role for Additional T-Cell Blockade?

Authors: Ogbuji, Vanessa, Paster, Irasema C, Recio-Boiles, Alejandro, Carew, Jennifer S, Nawrocki, Steffan T, Chipollini, Juan

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16010131

Paper Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression

Mingzhen Zhou, Ziyan Zhou, Lina Hu, Sidong Chen, Fanyan Meng, Jun Chen, Jie Shen · 2025 · Journal of Translational Medicine · DOI

Full title: Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression

Authors: Mingzhen Zhou, Ziyan Zhou, Lina Hu, Sidong Chen, Fanyan Meng, Jun Chen, Jie Shen

Year: 2025

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-025-06106-0

Paper Type I interferon-mediated tumor immunity and its role in immunotherapy

Yu, Renren, Zhu, Bo, Chen, Degao · 2022 · Cellular and Molecular Life Sciences · DOI

Full title: Type I interferon-mediated tumor immunity and its role in immunotherapy

Authors: Yu, Renren, Zhu, Bo, Chen, Degao

Year: 2022

Venue: Cellular and Molecular Life Sciences

DOI: https://doi.org/10.1007/s00018-022-04219-z

Paper Prognostic and predictive value of an immune infiltration signature in diffuse lower-grade gliomas.

Lairong Song, Jiancong Weng, Cheng-bei Li, X. Huo, Huan Li, S. Hao, Zhen Wu, Liang Wang, Da Li, Junting Zhang · 2020 · JCI Insight · DOI

Full title: Prognostic and predictive value of an immune infiltration signature in diffuse lower-grade gliomas.

Authors: Lairong Song, Jiancong Weng, Cheng-bei Li, X. Huo, Huan Li, S. Hao, Zhen Wu, Liang Wang, Da Li, Junting Zhang

Year: 2020

Venue: JCI Insight

DOI: https://doi.org/10.1172/jci.insight.133811

Paper Gastric cancer treatment: recent progress and future perspectives

Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua · 2023 · Journal of Hematology & Oncology · DOI

Full title: Gastric cancer treatment: recent progress and future perspectives

Authors: Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua

Year: 2023

Venue: Journal of Hematology & Oncology

DOI: https://doi.org/10.1186/s13045-023-01451-3

Paper Successful treatment of synchronous double lung and colon cancers using immune checkpoint inhibitors.

Matsuoka, Shuichi, Tokuyasu, Hirokazu, Arai, Katsunori, Sakai, Hiromitsu, Esumi, Chika, Yamasaki, Akira · 2026 · Internal medicine (Tokyo, Japan) · DOI

Full title: Successful treatment of synchronous double lung and colon cancers using immune checkpoint inhibitors.

Authors: Matsuoka, Shuichi, Tokuyasu, Hirokazu, Arai, Katsunori, Sakai, Hiromitsu, Esumi, Chika, Yamasaki, Akira

Year: 2026

Venue: Internal medicine (Tokyo, Japan)

DOI: https://doi.org/10.2169/internalmedicine.6293-25

Paper Progress in Target-Therapy with Breast Cancer

Yezhou Sun · 2024 · Highlights in Science Engineering and Technology · DOI

Full title: Progress in Target-Therapy with Breast Cancer

Authors: Yezhou Sun

Year: 2024

Venue: Highlights in Science Engineering and Technology

DOI: https://doi.org/10.54097/n316re10

Paper Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition.

Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph · 2017 · Oncotarget · DOI

Full title: Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition.

Authors: Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.13888

Paper Immune Escape and Immune Checkpoint-associated Therapies in the Tumour Microenvironment of Head and Neck Squamous Cell Carcinoma

Qin Yang · 2024 · Transactions on Materials, Biotechnology and Life Sciences · DOI

Full title: Immune Escape and Immune Checkpoint-associated Therapies in the Tumour Microenvironment of Head and Neck Squamous Cell Carcinoma

Authors: Qin Yang

Year: 2024

Venue: Transactions on Materials, Biotechnology and Life Sciences

DOI: https://doi.org/10.62051/mpv6h713

Paper Advances in immune therapies for the treatment of microsatellite instability‑high/deficient mismatch repair metastatic colorectal cancer (Review)

Choucair, Khalil, Radford, Maluki, Bansal, Ajay, Park, Robin, Saeed, Anwaar · 2021 · International Journal of Oncology · DOI

Full title: Advances in immune therapies for the treatment of microsatellite instability‑high/deficient mismatch repair metastatic colorectal cancer (Review)

Authors: Choucair, Khalil, Radford, Maluki, Bansal, Ajay, Park, Robin, Saeed, Anwaar

Year: 2021

Venue: International Journal of Oncology

DOI: https://doi.org/10.3892/ijo.2021.5254

Paper Biomimetic nanoparticles for tumor immunotherapy

Yu, Hanqing, Wu, Meng–Huang, Chen, Siyu, Song, Mingming, Yue, Yulin · 2022 · Frontiers in Bioengineering and Biotechnology · DOI

Full title: Biomimetic nanoparticles for tumor immunotherapy

Authors: Yu, Hanqing, Wu, Meng–Huang, Chen, Siyu, Song, Mingming, Yue, Yulin

Year: 2022

Venue: Frontiers in Bioengineering and Biotechnology

DOI: https://doi.org/10.3389/fbioe.2022.989881

Paper Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/- Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets.

Gide, Tuba N, Pires da Silva, Inês, Quek, Camelia, Ferguson, Peter M, Batten, Marcel, Shang, Ping, Ahmed, Tasnia, Menzies, Alexander M, Carlino, Matteo S, Saw, Robyn P M, Thompson, John F, Scolyer, Richard A, Long, Georgina V, Wilmott, James S · 2021 · Cancers · DOI

Full title: Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/- Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets.

Authors: Gide, Tuba N, Pires da Silva, Inês, Quek, Camelia, Ferguson, Peter M, Batten, Marcel, Shang, Ping, Ahmed, Tasnia, Menzies, Alexander M, Carlino, Matteo S, Saw, Robyn P M, Thompson, John F, Scolyer, Richard A, Long, Georgina V, Wilmott, James S

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13133186

Paper Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer.

Hanlin Jiang, Weiqiao Niu, Yujia Pan, Zongying Jiang, Jianwu Wu, Z. Qiao, Xinwei Jiang, Lining Huang · 2025 · Digestive Diseases and Sciences · DOI

Full title: Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer.

Authors: Hanlin Jiang, Weiqiao Niu, Yujia Pan, Zongying Jiang, Jianwu Wu, Z. Qiao, Xinwei Jiang, Lining Huang

Year: 2025

Venue: Digestive Diseases and Sciences

DOI: https://doi.org/10.1007/s10620-025-09546-2

Paper A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya · 2021 · Cancers · DOI

Full title: A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Authors: Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14010203

Paper Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions.

Chipuc, Stefania, Bogdan, Haineala, Serban, Dragos, Badiu, Dumitru Cristinel, Zgura, Anca, Anghel, Rodica · 2024 · Cancer diagnosis & prognosis · DOI

Full title: Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions.

Authors: Chipuc, Stefania, Bogdan, Haineala, Serban, Dragos, Badiu, Dumitru Cristinel, Zgura, Anca, Anghel, Rodica

Year: 2024

Venue: Cancer diagnosis & prognosis

DOI: https://doi.org/10.21873/cdp.10363

Paper Severe Immune-Related Pneumonitis With PD-1 Inhibitor After Progression on Previous PD-L1 Inhibitor in Small Cell Lung Cancer: A Case Report and Review of the Literature.

Liang, Xiuju, Guan, Yaping, Zhang, Bicheng, Liang, Jing, Wang, Baocheng, Li, Yan, Wang, Jun · 2019 · Frontiers in oncology · DOI

Full title: Severe Immune-Related Pneumonitis With PD-1 Inhibitor After Progression on Previous PD-L1 Inhibitor in Small Cell Lung Cancer: A Case Report and Review of the Literature.

Authors: Liang, Xiuju, Guan, Yaping, Zhang, Bicheng, Liang, Jing, Wang, Baocheng, Li, Yan, Wang, Jun

Year: 2019

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2019.01437

Paper Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma

Rovers, Sophie, Janssens, Annelies, Raskin, Jo, Pauwels, Patrick, Meerbeeck, Jan P. van, Smits, Evelien, Marcq, Elly · 2022 · Biomedicines · DOI

Full title: Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma

Authors: Rovers, Sophie, Janssens, Annelies, Raskin, Jo, Pauwels, Patrick, Meerbeeck, Jan P. van, Smits, Evelien, Marcq, Elly

Year: 2022

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines10030673

Paper Case report: Fatal overwhelming post-splenectomy infection in a patient with metastatic angiosarcoma treated with immunotherapy.

Torrado, Carlos, Baysal, Mehmet A, Chakraborty, Abhijit, Norris, Becky L, Khawaja, Fareed, Tsimberidou, Apostolia M · 2024 · Frontiers in immunology · DOI

Full title: Case report: Fatal overwhelming post-splenectomy infection in a patient with metastatic angiosarcoma treated with immunotherapy.

Authors: Torrado, Carlos, Baysal, Mehmet A, Chakraborty, Abhijit, Norris, Becky L, Khawaja, Fareed, Tsimberidou, Apostolia M

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1366271

Paper Immunotherapy of thymic epithelial tumors: molecular understandings and clinical perspectives

Yongqiang Ao, Jian Gao, Shuai Wang, Jiapeng Jiang, J. Deng, Haikun Wang, Bei Xu, Jian-Yong Ding · 2023 · Molecular Cancer · DOI

Full title: Immunotherapy of thymic epithelial tumors: molecular understandings and clinical perspectives

Authors: Yongqiang Ao, Jian Gao, Shuai Wang, Jiapeng Jiang, J. Deng, Haikun Wang, Bei Xu, Jian-Yong Ding

Year: 2023

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-023-01772-4

Paper Association of PD-L1 positivity with Epstein Barr virus infection and microsatellite instability in gastric carcinomas with lymphoid stroma

Sun Mi Lee, Hyunjoo Oh · 2024 · Scientific Reports · DOI

Full title: Association of PD-L1 positivity with Epstein Barr virus infection and microsatellite instability in gastric carcinomas with lymphoid stroma

Authors: Sun Mi Lee, Hyunjoo Oh

Year: 2024

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-024-81764-6

Paper Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer.

Qu, Fanjie, Wu, Shuang, Yu, WeiWei · 2024 · OncoTargets and therapy · DOI

Full title: Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer.

Authors: Qu, Fanjie, Wu, Shuang, Yu, WeiWei

Year: 2024

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S500281

Paper Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.

Ferrari, Silvia Martina, Fallahi, Poupak, Elia, Giusy, Ragusa, Francesca, Ruffilli, Ilaria, Patrizio, Armando, Galdiero, Maria Rosaria, Baldini, Enke, Ulisse, Salvatore, Marone, Gianni, Antonelli, Alessandro · 2019 · International journal of molecular sciences · DOI

Full title: Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.

Authors: Ferrari, Silvia Martina, Fallahi, Poupak, Elia, Giusy, Ragusa, Francesca, Ruffilli, Ilaria, Patrizio, Armando, Galdiero, Maria Rosaria, Baldini, Enke, Ulisse, Salvatore, Marone, Gianni, Antonelli, Alessandro

Year: 2019

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms20102560

Paper The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Response in Melanoma Patients.

Tomela, Katarzyna, Pietrzak, Bernadeta, Schmidt, Marcin, Mackiewicz, Andrzej · 2020 · Life (Basel, Switzerland) · DOI

Full title: The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Response in Melanoma Patients.

Authors: Tomela, Katarzyna, Pietrzak, Bernadeta, Schmidt, Marcin, Mackiewicz, Andrzej

Year: 2020

Venue: Life (Basel, Switzerland)

DOI: https://doi.org/10.3390/life10100219

Paper The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy.

Dong, Linyinxue, Tian, Xuechen, Zhao, Yunqi, Tu, Haohong, Wong, Aloysius, Yang, Yixin · 2022 · International journal of molecular sciences · DOI

Full title: The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy.

Authors: Dong, Linyinxue, Tian, Xuechen, Zhao, Yunqi, Tu, Haohong, Wong, Aloysius, Yang, Yixin

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232314775

Paper Overcoming resistance to PD-1/PD-L1 inhibitors in esophageal cancer.

Cheng, Chao, Zhuge, Lingdun, Xiao, Xin, Luan, Siyuan, Yuan, Yong · 2022 · Frontiers in oncology · DOI

Full title: Overcoming resistance to PD-1/PD-L1 inhibitors in esophageal cancer.

Authors: Cheng, Chao, Zhuge, Lingdun, Xiao, Xin, Luan, Siyuan, Yuan, Yong

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.955163

Paper Incidence of pneumonitis with CTLA-4 inhibitors in non-small cell lung cancer: a systematic review and meta-analysis.

Li, Wei, Xiong, Hao, Peng, Haiying, Yang, Ting, Fan, Li, Zhang, Yanlin · 2025 · Frontiers in medicine · DOI

Full title: Incidence of pneumonitis with CTLA-4 inhibitors in non-small cell lung cancer: a systematic review and meta-analysis.

Authors: Li, Wei, Xiong, Hao, Peng, Haiying, Yang, Ting, Fan, Li, Zhang, Yanlin

Year: 2025

Venue: Frontiers in medicine

DOI: https://doi.org/10.3389/fmed.2025.1614442

Paper Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy.

Ballot, Elise, Ladoire, Sylvain, Routy, Bertrand, Truntzer, Caroline, Ghiringhelli, François · 2020 · Cancers · DOI

Full title: Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy.

Authors: Ballot, Elise, Ladoire, Sylvain, Routy, Bertrand, Truntzer, Caroline, Ghiringhelli, François

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12092418

Paper Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.

Horsman, Michael R, Wittenborn, Thomas R, Nielsen, Patricia S, Elming, Pernille B · 2020 · International journal of molecular sciences · DOI

Full title: Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.

Authors: Horsman, Michael R, Wittenborn, Thomas R, Nielsen, Patricia S, Elming, Pernille B

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21134778

Paper New PD-L1 inhibitors in non-small cell lung cancer – impact of atezolizumab

N. Seetharamu, I. Preeshagul, K. Sullivan · 2017 · Lung Cancer · DOI

Full title: New PD-L1 inhibitors in non-small cell lung cancer – impact of atezolizumab

Authors: N. Seetharamu, I. Preeshagul, K. Sullivan

Year: 2017

Venue: Lung Cancer

DOI: https://doi.org/10.2147/lctt.s113177

Paper Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC).

De Battista, Davide, Yakymi, Rylee, Scheibe, Evangeline, Sato, Shinya, Gerstein, Hannah, Markowitz, Tovah E, Lack, Justin, Mereu, Roberto, Manieli, Cristina, Zamboni, Fausto, Farci, Patrizia · 2024 · Cancers · DOI

Full title: Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC).

Authors: De Battista, Davide, Yakymi, Rylee, Scheibe, Evangeline, Sato, Shinya, Gerstein, Hannah, Markowitz, Tovah E, Lack, Justin, Mereu, Roberto, Manieli, Cristina, Zamboni, Fausto, Farci, Patrizia

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16071370

Paper Efficacy and safety of PD-1/PD-L1 inhibitors in triple-negative breast cancer: a systematic review and meta-analysis.

Zhang, Meilin, Song, Jian, Yang, Hongguang, Jin, Feng, Zheng, Ang · 2022 · Acta oncologica (Stockholm, Sweden) · DOI

Full title: Efficacy and safety of PD-1/PD-L1 inhibitors in triple-negative breast cancer: a systematic review and meta-analysis.

Authors: Zhang, Meilin, Song, Jian, Yang, Hongguang, Jin, Feng, Zheng, Ang

Year: 2022

Venue: Acta oncologica (Stockholm, Sweden)

DOI: https://doi.org/10.1080/0284186X.2022.2106795

Paper Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours.

Masucci, Giuseppe V, Wersäll, Peter, Kiessling, Rolf, Lundqvist, Andreas, Lewensohn, Rolf · 2012 · Journal of translational medicine · DOI

Full title: Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours.

Authors: Masucci, Giuseppe V, Wersäll, Peter, Kiessling, Rolf, Lundqvist, Andreas, Lewensohn, Rolf

Year: 2012

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/1479-5876-10-104

Paper Small vessel vasculitis and dry gangrene secondary to combined CTLA-4 and PD-1 blockade in malignant mesothelioma

Kefas, Joanna, Harwood, Catherine, Lewis, Myles, Szlosarek, Peter W. · 2022 · BMC Rheumatology · DOI

Full title: Small vessel vasculitis and dry gangrene secondary to combined CTLA-4 and PD-1 blockade in malignant mesothelioma

Authors: Kefas, Joanna, Harwood, Catherine, Lewis, Myles, Szlosarek, Peter W.

Year: 2022

Venue: BMC Rheumatology

DOI: https://doi.org/10.1186/s41927-021-00238-8

Paper A Novel CTLA-4 affinity peptide for cancer immunotherapy by increasing the integrin αvβ3 targeting.

Zhou, Ying, Song, Shuyi, Yuan, Baomei, Wu, Yahong, Gao, Yanfeng, Wan, Guangming, Li, Guodong · 2022 · Discover oncology · DOI

Full title: A Novel CTLA-4 affinity peptide for cancer immunotherapy by increasing the integrin αvβ3 targeting.

Authors: Zhou, Ying, Song, Shuyi, Yuan, Baomei, Wu, Yahong, Gao, Yanfeng, Wan, Guangming, Li, Guodong

Year: 2022

Venue: Discover oncology

DOI: https://doi.org/10.1007/s12672-022-00562-6

Paper Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer

T. Veen, A. Kanani, D. Lea, K. Søreide · 2023 · Cancer Immunology and Immunotherapy · DOI

Full title: Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer

Authors: T. Veen, A. Kanani, D. Lea, K. Søreide

Year: 2023

Venue: Cancer Immunology and Immunotherapy

DOI: https://doi.org/10.1007/s00262-023-03480-w

Paper Characteristics of Immune Checkpoint Inhibitor-Induced Colitis: A Systematic Review.

Nakane, Tomoyuki, Mitsuyama, Keiichi, Yamauchi, Ryosuke, Kakuma, Tatsuyuki, Torimura, Takuji · 2023 · The Kurume medical journal · DOI

Full title: Characteristics of Immune Checkpoint Inhibitor-Induced Colitis: A Systematic Review.

Authors: Nakane, Tomoyuki, Mitsuyama, Keiichi, Yamauchi, Ryosuke, Kakuma, Tatsuyuki, Torimura, Takuji

Year: 2023

Venue: The Kurume medical journal

DOI: https://doi.org/10.2739/kurumemedj.MS682006

Paper Combination Immunotherapies to Overcome Intrinsic Resistance to Checkpoint Blockade in Microsatellite Stable Colorectal Cancer

Kim, Chang Woo, Chon, Hong Jae, Kim, Chan, Kim, Chan, Kim, Chan · 2021 · Cancers · DOI

Full title: Combination Immunotherapies to Overcome Intrinsic Resistance to Checkpoint Blockade in Microsatellite Stable Colorectal Cancer

Authors: Kim, Chang Woo, Chon, Hong Jae, Kim, Chan, Kim, Chan, Kim, Chan

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13194906

Paper Chemokines in the Landscape of Cancer Immunotherapy: How They and Their Receptors Can Be Used to Turn Cold Tumors into Hot Ones?

Karin, Nathan · 2021 · Cancers · DOI

Full title: Chemokines in the Landscape of Cancer Immunotherapy: How They and Their Receptors Can Be Used to Turn Cold Tumors into Hot Ones?

Authors: Karin, Nathan

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13246317

Paper The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma

Albrecht, Lea Jessica, Livingstone, Elisabeth, Zimmer, Lisa, Schadendorf, Dirk · 2023 · Current Oncology Reports · DOI

Full title: The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma

Authors: Albrecht, Lea Jessica, Livingstone, Elisabeth, Zimmer, Lisa, Schadendorf, Dirk

Year: 2023

Venue: Current Oncology Reports

DOI: https://doi.org/10.1007/s11912-023-01406-4

Paper Current knowledge about immunotherapy resistance for melanoma and potential predictive and prognostic biomarkers.

Song, Lanni, Yang, Yixin, Tian, Xuechen · 2024 · Cancer drug resistance (Alhambra, Calif.) · DOI

Full title: Current knowledge about immunotherapy resistance for melanoma and potential predictive and prognostic biomarkers.

Authors: Song, Lanni, Yang, Yixin, Tian, Xuechen

Year: 2024

Venue: Cancer drug resistance (Alhambra, Calif.)

DOI: https://doi.org/10.20517/cdr.2023.150

Paper Rapid onset type 1 diabetes with anti-PD-1 directed therapy.

Yun, Karen, Daniels, Gregory, Gold, Kathryn, Mccowen, Karen, Patel, Sandip Pravin · 2020 · Oncotarget · DOI

Full title: Rapid onset type 1 diabetes with anti-PD-1 directed therapy.

Authors: Yun, Karen, Daniels, Gregory, Gold, Kathryn, Mccowen, Karen, Patel, Sandip Pravin

Year: 2020

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.27665

Paper The Role of Immunotherapy to Overcome Resistance in Viral-Associated Head and Neck Cancer.

Pharaon, Rebecca R, Xing, Yan, Agulnik, Mark, Villaflor, Victoria M · 2021 · Frontiers in oncology · DOI

Full title: The Role of Immunotherapy to Overcome Resistance in Viral-Associated Head and Neck Cancer.

Authors: Pharaon, Rebecca R, Xing, Yan, Agulnik, Mark, Villaflor, Victoria M

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.649963

Paper CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.

Çakan, Elif, Wang, Meng, Dai, Yile, Mirouse, Adrien, Villanueva-Pachas, Clarence Rachel, Bouis, Delphine, Boeckers, Joshua M, Gera, Ruchi, Yraita, Sally, Clapp, Leslie, Perdigoto, Ana Luisa, Delmotte, Fabien R, Massad, Christopher, Bacchiocchi, Antonietta, Ring, Aaron M, Kluger, Yuval, Kluger, Harriet M, Herold, Kevan C, Meffre, Eric · 2025 · The Journal of clinical investigation · DOI

Full title: CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.

Authors: Çakan, Elif, Wang, Meng, Dai, Yile, Mirouse, Adrien, Villanueva-Pachas, Clarence Rachel, Bouis, Delphine, Boeckers, Joshua M, Gera, Ruchi, Yraita, Sally, Clapp, Leslie, Perdigoto, Ana Luisa, Delmotte, Fabien R, Massad, Christopher, Bacchiocchi, Antonietta, Ring, Aaron M, Kluger, Yuval, Kluger, Harriet M, Herold, Kevan C, Meffre, Eric

Year: 2025

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI189074

Paper Case Report: Circulating Myeloid-Derived Suppressive-Like Cells and Exhausted Immune Cells in Non-Small Cell Lung Cancer Patients Treated With Three Immune Checkpoint Inhibitors.

Bronte, Giuseppe, Verlicchi, Alberto, De Matteis, Serena, Rossi, Alice, Affatato, Alessandra, Sullo, Francesco Giulio, Gianni, Caterina, Canale, Matteo, Burgio, Marco Angelo, Delmonte, Angelo, Milella, Michele, Crinò, Lucio · 2021 · Frontiers in immunology · DOI

Full title: Case Report: Circulating Myeloid-Derived Suppressive-Like Cells and Exhausted Immune Cells in Non-Small Cell Lung Cancer Patients Treated With Three Immune Checkpoint Inhibitors.

Authors: Bronte, Giuseppe, Verlicchi, Alberto, De Matteis, Serena, Rossi, Alice, Affatato, Alessandra, Sullo, Francesco Giulio, Gianni, Caterina, Canale, Matteo, Burgio, Marco Angelo, Delmonte, Angelo, Milella, Michele, Crinò, Lucio

Year: 2021

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2021.672219

Paper Analysis of synergistic effects of PD-1 inhibitors and CTLA-4 inhibitors in HCC immunotherapy

Yuanlong Zhou, Jisen Zhao, Yuan Wang, Hao Lu · 2024 · MEDS Basic Medicine · DOI

Full title: Analysis of synergistic effects of PD-1 inhibitors and CTLA-4 inhibitors in HCC immunotherapy

Authors: Yuanlong Zhou, Jisen Zhao, Yuan Wang, Hao Lu

Year: 2024

Venue: MEDS Basic Medicine

DOI: https://doi.org/10.23977/medbm.2024.020219

Paper Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond

Lee, Yun Hua, Tai, David, Yip, Connie, Choo, Su Pin, Chew, Valerie · 2020 · Frontiers in Immunology · DOI

Full title: Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond

Authors: Lee, Yun Hua, Tai, David, Yip, Connie, Choo, Su Pin, Chew, Valerie

Year: 2020

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2020.568759

Paper Improving radiotherapy in cancer treatment: Promises and challenges

Chen, Helen H.W., Kuo, Macus Tien · 2017 · Oncotarget · DOI

Full title: Improving radiotherapy in cancer treatment: Promises and challenges

Authors: Chen, Helen H.W., Kuo, Macus Tien

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.18409

Paper Immune Checkpoint Therapy for Thymic Carcinoma

Jinhui Li, Fuling Mao, Hongyu Liu, Jun Chen · 2025 · Cancers · DOI

Full title: Immune Checkpoint Therapy for Thymic Carcinoma

Authors: Jinhui Li, Fuling Mao, Hongyu Liu, Jun Chen

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17203377

Paper Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production.

Curran, Michael A, Kim, Myoungjoo, Montalvo, Welby, Al-Shamkhani, Aymen, Allison, James P · 2011 · PloS one · DOI

Full title: Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production.

Authors: Curran, Michael A, Kim, Myoungjoo, Montalvo, Welby, Al-Shamkhani, Aymen, Allison, James P

Year: 2011

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0019499

Paper IL-15 in the Combination Immunotherapy of Cancer

Waldmann, Thomas A., Dubois, Sigrid, Miljković, Miloš D., Conlon, Kevin C. · 2020 · Frontiers in Immunology · DOI

Full title: IL-15 in the Combination Immunotherapy of Cancer

Authors: Waldmann, Thomas A., Dubois, Sigrid, Miljković, Miloš D., Conlon, Kevin C.

Year: 2020

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2020.00868

Paper Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway.

Momtaz, Parisa, Postow, Michael A · 2014 · Pharmacogenomics and personalized medicine · DOI

Full title: Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway.

Authors: Momtaz, Parisa, Postow, Michael A

Year: 2014

Venue: Pharmacogenomics and personalized medicine

DOI: https://doi.org/10.2147/PGPM.S53163

Paper Immune-Checkpoint Inhibitors-Induced Type 1 Diabetes Mellitus: From Its Molecular Mechanisms to Clinical Practice.

Cho, Yun Kyung, Jung, Chang Hee · 2023 · Diabetes & metabolism journal · DOI

Full title: Immune-Checkpoint Inhibitors-Induced Type 1 Diabetes Mellitus: From Its Molecular Mechanisms to Clinical Practice.

Authors: Cho, Yun Kyung, Jung, Chang Hee

Year: 2023

Venue: Diabetes & metabolism journal

DOI: https://doi.org/10.4093/dmj.2023.0072

Paper Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

David, Paul, Drabczyk-Pluta, Malgorzata, Pastille, Eva, Knuschke, Torben, Werner, Tanja, Honke, Nadine, Megger, Dominik A, Akhmetzyanova, Ilseyar, Shaabani, Namir, Eyking-Singer, Annette, Cario, Elke, Kershaw, Olivia, Gruber, Achim D, Tenbusch, Matthias, Dietze, Kirsten K, Trilling, Mirko, Liu, Jia, Schadendorf, Dirk, Streeck, Hendrik, Lang, Karl S, Xie, Youhua, Zimmer, Lisa, Sitek, Barbara, Paschen, Annette, Westendorf, Astrid M, Dittmer, Ulf, Zelinskyy, Gennadiy · 2020 · PLoS pathogens · DOI

Full title: Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

Authors: David, Paul, Drabczyk-Pluta, Malgorzata, Pastille, Eva, Knuschke, Torben, Werner, Tanja, Honke, Nadine, Megger, Dominik A, Akhmetzyanova, Ilseyar, Shaabani, Namir, Eyking-Singer, Annette, Cario, Elke, Kershaw, Olivia, Gruber, Achim D, Tenbusch, Matthias, Dietze, Kirsten K, Trilling, Mirko, Liu, Jia, Schadendorf, Dirk, Streeck, Hendrik, Lang, Karl S, Xie, Youhua, Zimmer, Lisa, Sitek, Barbara, Paschen, Annette, Westendorf, Astrid M, Dittmer, Ulf, Zelinskyy, Gennadiy

Year: 2020

Venue: PLoS pathogens

DOI: https://doi.org/10.1371/journal.ppat.1008340

Paper Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting.

Baldin, Alexey V, Savvateeva, Lyudmila V, Bazhin, Alexandr V, Zamyatnin, Andrey A · 2020 · Cancers · DOI

Full title: Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting.

Authors: Baldin, Alexey V, Savvateeva, Lyudmila V, Bazhin, Alexandr V, Zamyatnin, Andrey A

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12030590

Paper Incorporation of Combination Immunotherapy into the Treatment Paradigms of Gastrointestinal Cancers

J.D. Kratz, N. Uboha · 2023 · Oncology & Haematology · DOI

Full title: Incorporation of Combination Immunotherapy into the Treatment Paradigms of Gastrointestinal Cancers

Authors: J.D. Kratz, N. Uboha

Year: 2023

Venue: Oncology & Haematology

DOI: https://doi.org/10.17925/ohr.2023.19.2.1

Paper Germline microRNA-based signatures predict toxicity and response to anti-CTLA-4 therapy.

Weidhaas, Joanne B, McGreevy, Kristen M, Marco, Nicholas, Sundahl, Nora, Cabanski, Christopher R, Spencer, Christine, LaVallee, Theresa, Ost, Piet, Telesca, Donatello · 2025 · Journal of translational medicine · DOI

Full title: Germline microRNA-based signatures predict toxicity and response to anti-CTLA-4 therapy.

Authors: Weidhaas, Joanne B, McGreevy, Kristen M, Marco, Nicholas, Sundahl, Nora, Cabanski, Christopher R, Spencer, Christine, LaVallee, Theresa, Ost, Piet, Telesca, Donatello

Year: 2025

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-025-06842-3

Paper Immune Checkpoint Activity Regulates Polycystic Kidney Disease Progression

Kleczko, Emily K., Nguyen, Dustin T., Marsh, Kenneth H., Bauer, Colin, Li, Amy S., Furgeson, Seth B., Gitomer, Berenice Y., Chonchol, Michel B., Clambey, Eric T., Zimmerman, Kurt A., Nemenoff, Raphael A., Hopp, Katharina · 2022 · DOI

Full title: Immune Checkpoint Activity Regulates Polycystic Kidney Disease Progression

Authors: Kleczko, Emily K., Nguyen, Dustin T., Marsh, Kenneth H., Bauer, Colin, Li, Amy S., Furgeson, Seth B., Gitomer, Berenice Y., Chonchol, Michel B., Clambey, Eric T., Zimmerman, Kurt A., Nemenoff, Raphael A., Hopp, Katharina

Year: 2022

DOI: https://doi.org/10.1101/2022.04.24.489306

Paper Evaluation of CTLA-4 and PD-L1 Expression in Thyroid Carcinoma and Its Prognostic Significance.

Anand, Nidhi, Srivastava, Pallavi, Husain, Nuzhat, Agarwal, Deeksha, Gupta, Anurag, Pradhan, Roma · 2024 · Cureus · DOI

Full title: Evaluation of CTLA-4 and PD-L1 Expression in Thyroid Carcinoma and Its Prognostic Significance.

Authors: Anand, Nidhi, Srivastava, Pallavi, Husain, Nuzhat, Agarwal, Deeksha, Gupta, Anurag, Pradhan, Roma

Year: 2024

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.67004

Paper Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy.

Loo, Kimberly, Tsai, Katy K, Mahuron, Kelly, Liu, Jacqueline, Pauli, Mariela L, Sandoval, Priscila M, Nosrati, Adi, Lee, James, Chen, Lawrence, Hwang, Jimmy, Levine, Lauren S, Krummel, Matthew F, Algazi, Alain P, Pampaloni, Miguel, Alvarado, Michael D, Rosenblum, Michael D, Daud, Adil I · 2017 · JCI insight · DOI

Full title: Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy.

Authors: Loo, Kimberly, Tsai, Katy K, Mahuron, Kelly, Liu, Jacqueline, Pauli, Mariela L, Sandoval, Priscila M, Nosrati, Adi, Lee, James, Chen, Lawrence, Hwang, Jimmy, Levine, Lauren S, Krummel, Matthew F, Algazi, Alain P, Pampaloni, Miguel, Alvarado, Michael D, Rosenblum, Michael D, Daud, Adil I

Year: 2017

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.93433

Paper Combining PD-1/PD-L1 and CTLA-4 inhibitors for the treatment of colorectal cancer: A systematic review and meta-analysis

Xiao-hui Fan · 2024 · Highlights in Science Engineering and Technology · DOI

Full title: Combining PD-1/PD-L1 and CTLA-4 inhibitors for the treatment of colorectal cancer: A systematic review and meta-analysis

Authors: Xiao-hui Fan

Year: 2024

Venue: Highlights in Science Engineering and Technology

DOI: https://doi.org/10.54097/0shjns21

Paper Immunologic correlates in a CIC::DUX4 fusion-positive sarcoma responsive to dual immune checkpoint blockade.

Babatunde, Olayode O, Coca Membribes, Sara, Anthonescu, Cristina, Bradic, Martina, O'Malley, Bernard, Linkov, Irina, Bartlett, Edmund, Momtaz, Parisa, Alektiar, Kaled, Gounder, Mrinal M, Rosenbaum, Evan, Tap, William D, D'Angelo, Sandra P, Kelly, Ciara M · 2025 · NPJ precision oncology · DOI

Full title: Immunologic correlates in a CIC::DUX4 fusion-positive sarcoma responsive to dual immune checkpoint blockade.

Authors: Babatunde, Olayode O, Coca Membribes, Sara, Anthonescu, Cristina, Bradic, Martina, O'Malley, Bernard, Linkov, Irina, Bartlett, Edmund, Momtaz, Parisa, Alektiar, Kaled, Gounder, Mrinal M, Rosenbaum, Evan, Tap, William D, D'Angelo, Sandra P, Kelly, Ciara M

Year: 2025

Venue: NPJ precision oncology

DOI: https://doi.org/10.1038/s41698-025-00878-w

Paper Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo · 2020 · International Journal of Molecular Sciences · DOI

Full title: Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Authors: Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21134691

Paper Primary Malignant Melanoma of the Genitourinary System: A Systemic Review and Report of Eight Cases.

Khayyat, Azadeh, Esmaeil Pour, Mohammad Ali, Mousavi, Seyedreza, Khalili-Toosi, Amir-Reza, Amin, Ali · 2022 · Cureus · DOI

Full title: Primary Malignant Melanoma of the Genitourinary System: A Systemic Review and Report of Eight Cases.

Authors: Khayyat, Azadeh, Esmaeil Pour, Mohammad Ali, Mousavi, Seyedreza, Khalili-Toosi, Amir-Reza, Amin, Ali

Year: 2022

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.30444

Paper Next Steps in Immuno-Oncology: Enhancing Antitumor Effects Through Appropriate Patient Selection and Rationally Designed Combination Strategies

Salama, Moschos · 2020 · UNC Libraries · DOI

Full title: Next Steps in Immuno-Oncology: Enhancing Antitumor Effects Through Appropriate Patient Selection and Rationally Designed Combination Strategies

Authors: Salama, Moschos

Year: 2020

Venue: UNC Libraries

DOI: https://doi.org/10.17615/2v0z-2g85

Paper [Treg cell contribution to anti-CTLA-4 therapeutic effect].

Thierry, Kevin, Ménétrier-Caux, Christine · 2020 · Medecine sciences : M/S · DOI

Full title: [Treg cell contribution to anti-CTLA-4 therapeutic effect].

Authors: Thierry, Kevin, Ménétrier-Caux, Christine

Year: 2020

Venue: Medecine sciences : M/S

DOI: https://doi.org/10.1051/medsci/2019260

Paper Case Report: Thrombotic-Thrombocytopenic Purpura Following Ipilimumab and Nivolumab Combination Immunotherapy for Metastatic Melanoma

Mullally, William, Cooke, Fiachra, Crosbie, Ian, Kumar, Sanjay, Abernethy, V. E., Jordan, E., O’Connor, Matthew, Horgan, Anne M., Landers, R J, Naidoo, Jarushka, Calvert, Paula · 2022 · Frontiers in Immunology · DOI

Full title: Case Report: Thrombotic-Thrombocytopenic Purpura Following Ipilimumab and Nivolumab Combination Immunotherapy for Metastatic Melanoma

Authors: Mullally, William, Cooke, Fiachra, Crosbie, Ian, Kumar, Sanjay, Abernethy, V. E., Jordan, E., O’Connor, Matthew, Horgan, Anne M., Landers, R J, Naidoo, Jarushka, Calvert, Paula

Year: 2022

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2022.871217

Paper Emerging immunotherapies for metastasis.

Edwards, Sarah C, Hoevenaar, Wilma H M, Coffelt, Seth B · 2021 · British journal of cancer · DOI

Full title: Emerging immunotherapies for metastasis.

Authors: Edwards, Sarah C, Hoevenaar, Wilma H M, Coffelt, Seth B

Year: 2021

Venue: British journal of cancer

DOI: https://doi.org/10.1038/s41416-020-01160-5

Paper PD-1/PD-L1 inhibitors for locally advanced nasopharyngeal carcinoma: a systematic review and meta-analysis based on randomized controlled trials.

Liu, Xiaohan, Shang, Zhiyuan, Gao, Jiawei, Jiang, Nan, Wang, Jinpeng, Zhou, Dan, Gui, Yan · 2025 · BMC cancer · DOI

Full title: PD-1/PD-L1 inhibitors for locally advanced nasopharyngeal carcinoma: a systematic review and meta-analysis based on randomized controlled trials.

Authors: Liu, Xiaohan, Shang, Zhiyuan, Gao, Jiawei, Jiang, Nan, Wang, Jinpeng, Zhou, Dan, Gui, Yan

Year: 2025

Venue: BMC cancer

DOI: https://doi.org/10.1186/s12885-025-15229-y

Paper Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells

A. Vito, Omar Salem, N. El-Sayes, Ian Macfawn, Ana L. Portillo, K. Milne, D. Harrington, A. Ashkar, Y. Wan, S. Workenhe, B. Nelson, T. Bruno, K. Mossman · 2021 · Communications Biology · DOI

Full title: Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells

Authors: A. Vito, Omar Salem, N. El-Sayes, Ian Macfawn, Ana L. Portillo, K. Milne, D. Harrington, A. Ashkar, Y. Wan, S. Workenhe, B. Nelson, T. Bruno, K. Mossman

Year: 2021

Venue: Communications Biology

DOI: https://doi.org/10.1038/s42003-021-02375-9

Paper Current status of clinical trial research and application of immune checkpoint inhibitors for non-small cell lung cancer.

Wang, Fuli, Xia, Teng, Li, Zhiqiang, Gao, Xuzhu, Fang, Xinjian · 2023 · Frontiers in oncology · DOI

Full title: Current status of clinical trial research and application of immune checkpoint inhibitors for non-small cell lung cancer.

Authors: Wang, Fuli, Xia, Teng, Li, Zhiqiang, Gao, Xuzhu, Fang, Xinjian

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1213297

Paper Advances in understanding the role of immune checkpoint LAG-3 in tumor immunity: a comprehensive review.

Luo, Yingzhe, Cai, Xuebin, Yang, Biao, Lu, Facheng, Yi, Cheng, Wu, Guoyu · 2024 · Frontiers in oncology · DOI

Full title: Advances in understanding the role of immune checkpoint LAG-3 in tumor immunity: a comprehensive review.

Authors: Luo, Yingzhe, Cai, Xuebin, Yang, Biao, Lu, Facheng, Yi, Cheng, Wu, Guoyu

Year: 2024

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2024.1402837

Paper Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis.

Auch, Lauris Annatha Mariam, Sieber, Chloé, Lehnick, Dirk, Hug, Balthasar L · 2025 · BMC cancer · DOI

Full title: Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis.

Authors: Auch, Lauris Annatha Mariam, Sieber, Chloé, Lehnick, Dirk, Hug, Balthasar L

Year: 2025

Venue: BMC cancer

DOI: https://doi.org/10.1186/s12885-025-14733-5

Paper Improvements in Systemic Therapies for Advanced Malignant Mesothelioma.

Deiana, Chiara, Fabbri, Francesca, Tavolari, Simona, Palloni, Andrea, Brandi, Giovanni · 2023 · International journal of molecular sciences · DOI

Full title: Improvements in Systemic Therapies for Advanced Malignant Mesothelioma.

Authors: Deiana, Chiara, Fabbri, Francesca, Tavolari, Simona, Palloni, Andrea, Brandi, Giovanni

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms241310415

Paper Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors.

Kovács, Szonja Anna, Fekete, János Tibor, Győrffy, Balázs · 2023 · Acta pharmacologica Sinica · DOI

Full title: Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors.

Authors: Kovács, Szonja Anna, Fekete, János Tibor, Győrffy, Balázs

Year: 2023

Venue: Acta pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-023-01079-6

Paper Combination Strategies of Checkpoint Immunotherapy in Metastatic Breast Cancer.

Liu, Zhi Bing, Zhang, Luyan, Bian, Jia, Jian, Jinbo · 2020 · OncoTargets and therapy · DOI

Full title: Combination Strategies of Checkpoint Immunotherapy in Metastatic Breast Cancer.

Authors: Liu, Zhi Bing, Zhang, Luyan, Bian, Jia, Jian, Jinbo

Year: 2020

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S240655

Paper Spatially confined genome editing enables localized combination immunotherapy.

Yang, Xiaoyue, Tong, Laura, Pan, Yidan, Huang, Jin, Yi, Zhongchao, He, Daheng, Liu, Jingpeng, Wang, Chi, Liang, Ying, Tong, Sheng · 2026 · bioRxiv : the preprint server for biology · DOI

Full title: Spatially confined genome editing enables localized combination immunotherapy.

Authors: Yang, Xiaoyue, Tong, Laura, Pan, Yidan, Huang, Jin, Yi, Zhongchao, He, Daheng, Liu, Jingpeng, Wang, Chi, Liang, Ying, Tong, Sheng

Year: 2026

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.64898/2026.01.14.699490

Paper Anti-PD-1/PD-L1 Based Combination Immunotherapy to Boost Antigen-Specific CD8+ T Cell Response in Hepatocellular Carcinoma

Peña‐Asensio, Julia, Sánchez, Henar Calvo, Torralba, Miguel, Miquel, Joaquín, Sanz‐de‐Villalobos, E., Larrubia, J.R. · 2021 · Cancers · DOI

Full title: Anti-PD-1/PD-L1 Based Combination Immunotherapy to Boost Antigen-Specific CD8+ T Cell Response in Hepatocellular Carcinoma

Authors: Peña‐Asensio, Julia, Sánchez, Henar Calvo, Torralba, Miguel, Miquel, Joaquín, Sanz‐de‐Villalobos, E., Larrubia, J.R.

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13081922

Paper Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.

Ock, Chan-Young, Hwang, Jun-Eul, Keam, Bhumsuk, Kim, Sang-Bae, Shim, Jae-Jun, Jang, Hee-Jin, Park, Sarang, Sohn, Bo Hwa, Cha, Minse, Ajani, Jaffer A, Kopetz, Scott, Lee, Keun-Wook, Kim, Tae Min, Heo, Dae Seog, Lee, Ju-Seog · 2017 · Nature communications · DOI

Full title: Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.

Authors: Ock, Chan-Young, Hwang, Jun-Eul, Keam, Bhumsuk, Kim, Sang-Bae, Shim, Jae-Jun, Jang, Hee-Jin, Park, Sarang, Sohn, Bo Hwa, Cha, Minse, Ajani, Jaffer A, Kopetz, Scott, Lee, Keun-Wook, Kim, Tae Min, Heo, Dae Seog, Lee, Ju-Seog

Year: 2017

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-017-01018-0

Paper Thymosin α1 Combined with PD-1/PD-L1 Inhibitor Plus Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer : A Retrospective Analysis.

Wang, Hong, Wang, Lixia, Zhong, Heqing, Li, Zhendong · 2025 · Cancer management and research · DOI

Full title: Thymosin α1 Combined with PD-1/PD-L1 Inhibitor Plus Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer : A Retrospective Analysis.

Authors: Wang, Hong, Wang, Lixia, Zhong, Heqing, Li, Zhendong

Year: 2025

Venue: Cancer management and research

DOI: https://doi.org/10.2147/CMAR.S542744

Paper PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice.

Frijlink, Elselien, Bosma, Douwe M T, Busselaar, Julia, Battaglia, Thomas W, Staal, Mo D, Verbrugge, Inge, Borst, Jannie · 2024 · The Journal of clinical investigation · DOI

Full title: PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice.

Authors: Frijlink, Elselien, Bosma, Douwe M T, Busselaar, Julia, Battaglia, Thomas W, Staal, Mo D, Verbrugge, Inge, Borst, Jannie

Year: 2024

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI171154

Paper Current and emerging therapies for first line treatment of metastatic clear cell renal cell carcinoma

Serzan, Michael, Atkins, Michael B. · 2021 · Journal of Cancer Metastasis and Treatment · DOI

Full title: Current and emerging therapies for first line treatment of metastatic clear cell renal cell carcinoma

Authors: Serzan, Michael, Atkins, Michael B.

Year: 2021

Venue: Journal of Cancer Metastasis and Treatment

DOI: https://doi.org/10.20517/2394-4722.2021.76

Paper Editorial: Toxicity Mechanism and Clinical Features of PD-1/PD-L1 Inhibitors in Treatment of Cancer, Volume I.

Kong, Xiangyi, Sullivan, Ryan J, Wu, Caisheng, Zhang, Lin, Jiang, Yu · 2022 · Frontiers in pharmacology · DOI

Full title: Editorial: Toxicity Mechanism and Clinical Features of PD-1/PD-L1 Inhibitors in Treatment of Cancer, Volume I.

Authors: Kong, Xiangyi, Sullivan, Ryan J, Wu, Caisheng, Zhang, Lin, Jiang, Yu

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.898368

Paper Programmed Cell Death Protein 1 (PD-1) and Programmed Cell Death Ligand 1 (PD-L1) Immunotherapy: A Promising Breakthrough in Cancer Therapeutics.

Abaza, Abdelrahman, Sid Idris, Faten, Anis Shaikh, Humna, Vahora, Ilma, Moparthi, Kiran Prasad, Al Rushaidi, Majdah T, Muddam, Meghana Reddy, Obajeun, Omobolanle A, Jaramillo, Arturo P, Khan, Safeera · 2023 · Cureus · DOI

Full title: Programmed Cell Death Protein 1 (PD-1) and Programmed Cell Death Ligand 1 (PD-L1) Immunotherapy: A Promising Breakthrough in Cancer Therapeutics.

Authors: Abaza, Abdelrahman, Sid Idris, Faten, Anis Shaikh, Humna, Vahora, Ilma, Moparthi, Kiran Prasad, Al Rushaidi, Majdah T, Muddam, Meghana Reddy, Obajeun, Omobolanle A, Jaramillo, Arturo P, Khan, Safeera

Year: 2023

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.44582

Paper PRKAR1B as an oncogenic biomarker for diagnostic and prognostic stratification of tumor immunity, proliferation, and migration in head and neck squamous cell carcinoma

Peng Zhao, Kang Li, WuFeng Xiu, Zhaokun Liu, Yanxiao Huang, Youfan Jiang, Peng Zhang, L. Peng · 2026 · Frontiers in Immunology · DOI

Full title: PRKAR1B as an oncogenic biomarker for diagnostic and prognostic stratification of tumor immunity, proliferation, and migration in head and neck squamous cell carcinoma

Authors: Peng Zhao, Kang Li, WuFeng Xiu, Zhaokun Liu, Yanxiao Huang, Youfan Jiang, Peng Zhang, L. Peng

Year: 2026

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2026.1770459

Paper Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer.

Wada, Satoshi, Jackson, Christopher M, Yoshimura, Kiyoshi, Yen, Hung-Rong, Getnet, Derese, Harris, Timothy J, Goldberg, Monica V, Bruno, Tullia C, Grosso, Joseph F, Durham, Nicholas, Netto, George J, Pardoll, Drew M, Drake, Charles G · 2013 · Journal of translational medicine · DOI

Full title: Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer.

Authors: Wada, Satoshi, Jackson, Christopher M, Yoshimura, Kiyoshi, Yen, Hung-Rong, Getnet, Derese, Harris, Timothy J, Goldberg, Monica V, Bruno, Tullia C, Grosso, Joseph F, Durham, Nicholas, Netto, George J, Pardoll, Drew M, Drake, Charles G

Year: 2013

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/1479-5876-11-89

Paper Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.

Mann, J E, Hoesli, R, Michmerhuizen, N L, Devenport, S N, Ludwig, M L, Vandenberg, T R, Matovina, C, Jawad, N, Mierzwa, M, Shuman, A G, Spector, M E, Brenner, J C · 2017 · Journal of Cancer · DOI

Full title: Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.

Authors: Mann, J E, Hoesli, R, Michmerhuizen, N L, Devenport, S N, Ludwig, M L, Vandenberg, T R, Matovina, C, Jawad, N, Mierzwa, M, Shuman, A G, Spector, M E, Brenner, J C

Year: 2017

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.17547

Paper Musculoskeletal adverse events induced by immune checkpoint inhibitors: a large-scale pharmacovigilance study.

Liu, Hao, Li, Yumin, Li, Jie, Zhang, Qiongchi, Wu, Jingtao, Li, Xinyu, Meng, Liesu, Cao, Shuai, Li, Haopeng · 2023 · Frontiers in pharmacology · DOI

Full title: Musculoskeletal adverse events induced by immune checkpoint inhibitors: a large-scale pharmacovigilance study.

Authors: Liu, Hao, Li, Yumin, Li, Jie, Zhang, Qiongchi, Wu, Jingtao, Li, Xinyu, Meng, Liesu, Cao, Shuai, Li, Haopeng

Year: 2023

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2023.1199031

Paper Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease.

Borriello, Francesco, Galdiero, Maria Rosaria, Varricchi, Gilda, Loffredo, Stefania, Spadaro, Giuseppe, Marone, Gianni · 2019 · International journal of molecular sciences · DOI

Full title: Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease.

Authors: Borriello, Francesco, Galdiero, Maria Rosaria, Varricchi, Gilda, Loffredo, Stefania, Spadaro, Giuseppe, Marone, Gianni

Year: 2019

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms20040834

Paper Mutations Associated with No Durable Clinical Benefit to Immune Checkpoint Blockade in Non-S-Cell Lung Cancer.

Zhu, Guangsheng, Ren, Dian, Lei, Xi, Shi, Ruifeng, Zhu, Shuai, Zhou, Ning, Zu, Lingling, Mello, Ramon Andrade De, Chen, Jun, Xu, Song · 2021 · Cancers · DOI

Full title: Mutations Associated with No Durable Clinical Benefit to Immune Checkpoint Blockade in Non-S-Cell Lung Cancer.

Authors: Zhu, Guangsheng, Ren, Dian, Lei, Xi, Shi, Ruifeng, Zhu, Shuai, Zhou, Ning, Zu, Lingling, Mello, Ramon Andrade De, Chen, Jun, Xu, Song

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13061397

Paper Targeting immune checkpoints in hematological malignancies.

Salik, Basit, Smyth, Mark J, Nakamura, Kyohei · 2020 · Journal of hematology & oncology · DOI

Full title: Targeting immune checkpoints in hematological malignancies.

Authors: Salik, Basit, Smyth, Mark J, Nakamura, Kyohei

Year: 2020

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-020-00947-6

Paper TremelImumab and Durvalumab Combination for the Non-OperatIve Management (NOM) of Microsatellite InstabiliTY (MSI)-High Resectable Gastric or Gastroesophageal Junction Cancer: The Multicentre, Single-Arm, Multi-Cohort, Phase II INFINITY Study

Raimondi, Alessandra, Palermo, Federica, Prisciandaro, Michele, Aglietta, Massimo, Antonuzzo, Lorenzo, Aprile, Giuseppe, Berardi, Rossana, Cardellino, Giovanni Gerardo, Manzoni, Giovanni De, Vita, Ferdinando De, Maïo, Massimo Di, Fornaro, Lorenzo, Frassineti, Giovanni Luca, Granetto, Cristina, Iachetta, Francesco, Lonardi, Sara, Murialdo, Roberto, Ongaro, Elena, Pucci, Francesca, Ratti, Margherita, Silvestris, Nicola, Smiroldo, Valeria, Spallanzani, Andrea, Strippoli, Antonia, Tamberi, Stefano, Tamburini, Emiliano, Zaniboni, Alberto, Bartolomeo, Maria Di, Cremolini, Chiara, Sposito, Carlo, Mazzaferro, Vincenzo, Pietrantonio, Filippo · 2021 · Cancers · DOI

Full title: TremelImumab and Durvalumab Combination for the Non-OperatIve Management (NOM) of Microsatellite InstabiliTY (MSI)-High Resectable Gastric or Gastroesophageal Junction Cancer: The Multicentre, Single-Arm, Multi-Cohort, Phase II INFINITY Study

Authors: Raimondi, Alessandra, Palermo, Federica, Prisciandaro, Michele, Aglietta, Massimo, Antonuzzo, Lorenzo, Aprile, Giuseppe, Berardi, Rossana, Cardellino, Giovanni Gerardo, Manzoni, Giovanni De, Vita, Ferdinando De, Maïo, Massimo Di, Fornaro, Lorenzo, Frassineti, Giovanni Luca, Granetto, Cristina, Iachetta, Francesco, Lonardi, Sara, Murialdo, Roberto, Ongaro, Elena, Pucci, Francesca, Ratti, Margherita, Silvestris, Nicola, Smiroldo, Valeria, Spallanzani, Andrea, Strippoli, Antonia, Tamberi, Stefano, Tamburini, Emiliano, Zaniboni, Alberto, Bartolomeo, Maria Di, Cremolini, Chiara, Sposito, Carlo, Mazzaferro, Vincenzo, Pietrantonio, Filippo

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13112839

Paper Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.

Schoenfeld, David A, Djureinovic, Dijana, Su, David G, Zhang, Lin, Lu, Benjamin Y, Kamga, Larisa, Mann, Jacqueline E, Huck, John D, Hurwitz, Michael, Braun, David A, Jilaveanu, Lucia, Ring, Aaron M, Kluger, Harriet M · 2024 · JCI insight · DOI

Full title: Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.

Authors: Schoenfeld, David A, Djureinovic, Dijana, Su, David G, Zhang, Lin, Lu, Benjamin Y, Kamga, Larisa, Mann, Jacqueline E, Huck, John D, Hurwitz, Michael, Braun, David A, Jilaveanu, Lucia, Ring, Aaron M, Kluger, Harriet M

Year: 2024

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.184545

Paper Severe autoimmune hemolytic anemia following immunotherapy with checkpoint inhibitors in two patients with metastatic melanoma: a case report.

Fetter, Tanja, Fietz, Simon, Bertlich, Maya, Braegelmann, Christine, de Vos-Hillebrand, Luka, Wenzel, Joerg, Heine, Annkristin, Landsberg, Jennifer, Jansen, Philipp · 2024 · Frontiers in immunology · DOI

Full title: Severe autoimmune hemolytic anemia following immunotherapy with checkpoint inhibitors in two patients with metastatic melanoma: a case report.

Authors: Fetter, Tanja, Fietz, Simon, Bertlich, Maya, Braegelmann, Christine, de Vos-Hillebrand, Luka, Wenzel, Joerg, Heine, Annkristin, Landsberg, Jennifer, Jansen, Philipp

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1342845

Paper In Situ Vaccination by Tumor Ablation: Principles and Prospects for Systemic Antitumor Immunity.

Chikovani, Tinatin, Magen, Eli · 2025 · Vaccines · DOI

Full title: In Situ Vaccination by Tumor Ablation: Principles and Prospects for Systemic Antitumor Immunity.

Authors: Chikovani, Tinatin, Magen, Eli

Year: 2025

Venue: Vaccines

DOI: https://doi.org/10.3390/vaccines13111114

Paper T-cell exhaustion in the tumor microenvironment

Jiang, Yuyong, Li, Yongsheng, Zhu, Bo · 2015 · Cell Death and Disease · DOI

Full title: T-cell exhaustion in the tumor microenvironment

Authors: Jiang, Yuyong, Li, Yongsheng, Zhu, Bo

Year: 2015

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2015.162

Paper Efficiency in different immunotherapy of cancer: literature review

K. A. Gaptulbarova, M. Tsyganov, M. Ibragimova, A. Pevzner, L. V. Spirina, N. Litviakov · 2021 · Advances in Molecular Oncology · DOI

Full title: Efficiency in different immunotherapy of cancer: literature review

Authors: K. A. Gaptulbarova, M. Tsyganov, M. Ibragimova, A. Pevzner, L. V. Spirina, N. Litviakov

Year: 2021

Venue: Advances in Molecular Oncology

DOI: https://doi.org/10.17650/2313-805x-2021-8-4-8-20

Paper Anti-PD1 does not improve pyroptosis induced by γδ T cells but promotes tumor regression in a pleural mesothelioma mouse model

Lui, Ka Sin, Ye, Zuodong, Chan, Hoi Ching, Tanaka, Yoshimasa, Cheung, Allen Ka Loon · 2023 · Frontiers in Immunology · DOI

Full title: Anti-PD1 does not improve pyroptosis induced by γδ T cells but promotes tumor regression in a pleural mesothelioma mouse model

Authors: Lui, Ka Sin, Ye, Zuodong, Chan, Hoi Ching, Tanaka, Yoshimasa, Cheung, Allen Ka Loon

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1282710

Paper Increased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunction and Prognosis?

Woodard, Gavitt A., Cho, Christina, Chen, Lieping · 2023 · Annals of Surgical Oncology · DOI

Full title: Increased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunction and Prognosis?

Authors: Woodard, Gavitt A., Cho, Christina, Chen, Lieping

Year: 2023

Venue: Annals of Surgical Oncology

DOI: https://doi.org/10.1245/s10434-023-14388-1

Paper PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Xu, Ling, Liu, Lian, Yao, Danlin, Zeng, Xiangbo, Zhang, Yikai, Lai, Jing, Zhong, Jun, Zha, Xianfeng, Zheng, Runhui, Lu, Yuhong, Li, Minming, Jin, Zhenyi, Subramanyam, Sudheendra Hebbar, Chen, Shaohua, Huang, Xin, Li, Yangqiu · 2021 · Frontiers in Oncology · DOI

Full title: PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Authors: Xu, Ling, Liu, Lian, Yao, Danlin, Zeng, Xiangbo, Zhang, Yikai, Lai, Jing, Zhong, Jun, Zha, Xianfeng, Zheng, Runhui, Lu, Yuhong, Li, Minming, Jin, Zhenyi, Subramanyam, Sudheendra Hebbar, Chen, Shaohua, Huang, Xin, Li, Yangqiu

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.686156

Paper Association between immune check point inhibitors and digestive system inflammatory adverse reactions: evidence from pharmacovigilance analysis and systematic review.

Zou, Ya, Li, Qinchuan, Zhou, Lu, Lu, Yun, Wei, Hua, Zhou, Yan, Lin, Shibo, Guo, Xirui, Yan, Shihao, Wang, Hongju, Xie, Fangqing, Liu, Chun, Chen, Li · 2025 · Frontiers in pharmacology · DOI

Full title: Association between immune check point inhibitors and digestive system inflammatory adverse reactions: evidence from pharmacovigilance analysis and systematic review.

Authors: Zou, Ya, Li, Qinchuan, Zhou, Lu, Lu, Yun, Wei, Hua, Zhou, Yan, Lin, Shibo, Guo, Xirui, Yan, Shihao, Wang, Hongju, Xie, Fangqing, Liu, Chun, Chen, Li

Year: 2025

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2025.1684475

Paper Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.

Shen, Ying-Chun, Ghasemzadeh, Ali, Kochel, Christina M, Nirschl, Thomas R, Francica, Brian J, Lopez-Bujanda, Zoila A, Carrera Haro, Maria A, Tam, Ada, Anders, Robert A, Selby, Mark J, Korman, Alan J, Drake, Charles G · 2018 · Prostate cancer and prostatic diseases · DOI

Full title: Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.

Authors: Shen, Ying-Chun, Ghasemzadeh, Ali, Kochel, Christina M, Nirschl, Thomas R, Francica, Brian J, Lopez-Bujanda, Zoila A, Carrera Haro, Maria A, Tam, Ada, Anders, Robert A, Selby, Mark J, Korman, Alan J, Drake, Charles G

Year: 2018

Venue: Prostate cancer and prostatic diseases

DOI: https://doi.org/10.1038/s41391-017-0013-x

Paper Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma.

Lorenzo-Sanz, Laura, Lopez-Cerda, Marta, da Silva-Diz, Victoria, Artés, Marta H, Llop, Sandra, Penin, Rosa M, Bermejo, Josep Oriol, Gonzalez-Suarez, Eva, Esteller, Manel, Viñals, Francesc, Espinosa, Enrique, Oliva, Marc, Piulats, Josep M, Martin-Liberal, Juan, Muñoz, Purificación · 2024 · Nature communications · DOI

Full title: Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma.

Authors: Lorenzo-Sanz, Laura, Lopez-Cerda, Marta, da Silva-Diz, Victoria, Artés, Marta H, Llop, Sandra, Penin, Rosa M, Bermejo, Josep Oriol, Gonzalez-Suarez, Eva, Esteller, Manel, Viñals, Francesc, Espinosa, Enrique, Oliva, Marc, Piulats, Josep M, Martin-Liberal, Juan, Muñoz, Purificación

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-49718-8

Paper On the Other Side: Manipulating the Immune Checkpoint Landscape of Dendritic Cells to Enhance Cancer Immunotherapy.

Kong, Benjamin Y, Bolton, Holly, Kim, Julius W, Silveira, Pablo A, Fromm, Phillip D, Clark, Georgina J · 2019 · Frontiers in oncology · DOI

Full title: On the Other Side: Manipulating the Immune Checkpoint Landscape of Dendritic Cells to Enhance Cancer Immunotherapy.

Authors: Kong, Benjamin Y, Bolton, Holly, Kim, Julius W, Silveira, Pablo A, Fromm, Phillip D, Clark, Georgina J

Year: 2019

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2019.00050

Paper Hepatotoxicity of ICI monotherapy or combination therapy in HCC: A systematic review and meta-analysis.

Lu, Yuping, Lin, Jing, Lu, Yufeng, Lin, Luping, Zheng, Shicheng, Chen, Yu, Huang, Sha · 2025 · PloS one · DOI

Full title: Hepatotoxicity of ICI monotherapy or combination therapy in HCC: A systematic review and meta-analysis.

Authors: Lu, Yuping, Lin, Jing, Lu, Yufeng, Lin, Luping, Zheng, Shicheng, Chen, Yu, Huang, Sha

Year: 2025

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0323023

Paper Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired

H. Marei, A. Hasan, G. Pozzoli, C. Cenciarelli · 2023 · Cancer Cell International · DOI

Full title: Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired

Authors: H. Marei, A. Hasan, G. Pozzoli, C. Cenciarelli

Year: 2023

Venue: Cancer Cell International

DOI: https://doi.org/10.1186/s12935-023-02902-0

Paper Targeting Multiple Receptors to Increase Checkpoint Blockade Efficacy.

Zahavi, David J, Weiner, Louis M · 2019 · International journal of molecular sciences · DOI

Full title: Targeting Multiple Receptors to Increase Checkpoint Blockade Efficacy.

Authors: Zahavi, David J, Weiner, Louis M

Year: 2019

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms20010158

Paper Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies

Nahar, Saifun, Huang, Yue, Nagy, Bethany A., Zebala, John A., Maeda, Dean Y., Rudloff, Udo, Oppenheim, Joost J., Yang, De · 2023 · Cancers · DOI

Full title: Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies

Authors: Nahar, Saifun, Huang, Yue, Nagy, Bethany A., Zebala, John A., Maeda, Dean Y., Rudloff, Udo, Oppenheim, Joost J., Yang, De

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15082366

Paper TIGIT, a novel immune checkpoint therapy for melanoma.

Tang, Wei, Chen, Jun, Ji, Tianlong, Cong, Xiufeng · 2023 · Cell death & disease · DOI

Full title: TIGIT, a novel immune checkpoint therapy for melanoma.

Authors: Tang, Wei, Chen, Jun, Ji, Tianlong, Cong, Xiufeng

Year: 2023

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-023-05961-3

Paper Beyond checkpoint inhibitors: the three generations of immunotherapy.

Schaub, John, Tang, Shou-Ching · 2025 · Clinical and experimental medicine · DOI

Full title: Beyond checkpoint inhibitors: the three generations of immunotherapy.

Authors: Schaub, John, Tang, Shou-Ching

Year: 2025

Venue: Clinical and experimental medicine

DOI: https://doi.org/10.1007/s10238-024-01546-2

Paper Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity.

Cao, K, Wang, G, Li, W, Zhang, L, Wang, R, Huang, Y, Du, L, Jiang, J, Wu, C, He, X, Roberts, A I, Li, F, Rabson, A B, Wang, Y, Shi, Y · 2015 · Oncogene · DOI

Full title: Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity.

Authors: Cao, K, Wang, G, Li, W, Zhang, L, Wang, R, Huang, Y, Du, L, Jiang, J, Wu, C, He, X, Roberts, A I, Li, F, Rabson, A B, Wang, Y, Shi, Y

Year: 2015

Venue: Oncogene

DOI: https://doi.org/10.1038/onc.2015.46

Paper Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Li, Shan, Shen, Liangfang · 2020 · Journal of Cancer · DOI

Full title: Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Authors: Li, Shan, Shen, Liangfang

Year: 2020

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.44408

Paper A surprising complete response to cadonilimab in a primary metastatic cervical cancer: a case report.

Yu, Haijuan, Lin, Jie, Chen, Jian, Chen, Lijun, Zou, Jianping, Liu, Bin, Hu, Dan, Xiao, Youping, Yu, Linhao, Sun, Yang · 2024 · Frontiers in immunology · DOI

Full title: A surprising complete response to cadonilimab in a primary metastatic cervical cancer: a case report.

Authors: Yu, Haijuan, Lin, Jie, Chen, Jian, Chen, Lijun, Zou, Jianping, Liu, Bin, Hu, Dan, Xiao, Youping, Yu, Linhao, Sun, Yang

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1494138

Paper Workshop on immunotherapy combinations. Society for Immunotherapy of Cancer annual meeting Bethesda, November 3, 2011.

Martinez Forero, Ivan, Okada, Hideho, Topalian, Suzanne L, Gajewski, Thomas F, Korman, Alan J, Melero, Ignacio · 2012 · Journal of translational medicine · DOI

Full title: Workshop on immunotherapy combinations. Society for Immunotherapy of Cancer annual meeting Bethesda, November 3, 2011.

Authors: Martinez Forero, Ivan, Okada, Hideho, Topalian, Suzanne L, Gajewski, Thomas F, Korman, Alan J, Melero, Ignacio

Year: 2012

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/1479-5876-10-108

Paper Immunotherapy in Recurrent Ovarian Cancer

Chen, Keyao, Wang, Jingjing, Yang, Meng, Deng, Shaoqiong, Sun, Li · 2025 · Biomedicines · DOI

Full title: Immunotherapy in Recurrent Ovarian Cancer

Authors: Chen, Keyao, Wang, Jingjing, Yang, Meng, Deng, Shaoqiong, Sun, Li

Year: 2025

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines13010168

Paper Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.

Selby, Mark J, Engelhardt, John J, Johnston, Robert J, Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M, Blanset, Diann, Korman, Alan J · 2016 · PloS one · DOI

Full title: Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.

Authors: Selby, Mark J, Engelhardt, John J, Johnston, Robert J, Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M, Blanset, Diann, Korman, Alan J

Year: 2016

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0167251

Paper miRNA-Based Therapeutics in the Era of Immune-Checkpoint Inhibitors.

Huemer, Florian, Leisch, Michael, Geisberger, Roland, Zaborsky, Nadja, Greil, Richard · 2021 · Pharmaceuticals (Basel, Switzerland) · DOI

Full title: miRNA-Based Therapeutics in the Era of Immune-Checkpoint Inhibitors.

Authors: Huemer, Florian, Leisch, Michael, Geisberger, Roland, Zaborsky, Nadja, Greil, Richard

Year: 2021

Venue: Pharmaceuticals (Basel, Switzerland)

DOI: https://doi.org/10.3390/ph14020089

Paper Immunotherapy in Hepatocellular Carcinoma.

Fulgenzi, Claudia A M, Talbot, Thomas, Murray, Sam M, Silletta, Marianna, Vincenzi, Bruno, Cortellini, Alessio, Pinato, David J · 2021 · Current treatment options in oncology · DOI

Full title: Immunotherapy in Hepatocellular Carcinoma.

Authors: Fulgenzi, Claudia A M, Talbot, Thomas, Murray, Sam M, Silletta, Marianna, Vincenzi, Bruno, Cortellini, Alessio, Pinato, David J

Year: 2021

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-021-00886-5

Paper Overcoming immune evasion with innovative multi-target approaches for glioblastoma

Su, Hai, Yin, Peng, Wu, Yi‐Long, Zeng, Xiaoli · 2025 · Frontiers in Immunology · DOI

Full title: Overcoming immune evasion with innovative multi-target approaches for glioblastoma

Authors: Su, Hai, Yin, Peng, Wu, Yi‐Long, Zeng, Xiaoli

Year: 2025

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2025.1541467

Paper Clinical utility of nivolumab in the treatment of advanced melanoma.

Asmar, Ramsey, Yang, Jessica, Carvajal, Richard D · 2016 · Therapeutics and clinical risk management · DOI

Full title: Clinical utility of nivolumab in the treatment of advanced melanoma.

Authors: Asmar, Ramsey, Yang, Jessica, Carvajal, Richard D

Year: 2016

Venue: Therapeutics and clinical risk management

DOI: https://doi.org/10.2147/TCRM.S78039

Paper - **DOI:** 10.14738/bjhr.1202.18696 - **Authors:** Tahir Abbas, V. Sundaram - **Year:** 2025 - **Journal:** British Journal of Healthcare and Medical Research

Tahir Abbas, V. Sundaram · 2025 · British Journal of Healthcare and Medical Research · DOI

Full title: - **DOI:** 10.14738/bjhr.1202.18696 - **Authors:** Tahir Abbas, V. Sundaram - **Year:** 2025 - **Journal:** British Journal of Healthcare and Medical Research

Authors: Tahir Abbas, V. Sundaram

Year: 2025

Venue: British Journal of Healthcare and Medical Research

DOI: https://doi.org/10.14738/bjhr.1202.18696

Paper ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer.

Kyte, J A, Andresen, N K, Russnes, H G, Fretland, S Ø, Falk, R S, Lingjærde, O C, Naume, B · 2020 · Journal of translational medicine · DOI

Full title: ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer.

Authors: Kyte, J A, Andresen, N K, Russnes, H G, Fretland, S Ø, Falk, R S, Lingjærde, O C, Naume, B

Year: 2020

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-020-02421-w

Paper Inhibitors of the CD73-adenosinergic checkpoint as promising combinatory agents for conventional and advanced cancer immunotherapy.

Kurago, Zoya, Guo, Gang, Shi, Huidong, Bollag, Roni J, Groves, Michael W, Byrd, J Kenneth, Cui, Yan · 2023 · Frontiers in immunology · DOI

Full title: Inhibitors of the CD73-adenosinergic checkpoint as promising combinatory agents for conventional and advanced cancer immunotherapy.

Authors: Kurago, Zoya, Guo, Gang, Shi, Huidong, Bollag, Roni J, Groves, Michael W, Byrd, J Kenneth, Cui, Yan

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1212209

Paper Inflammatory Markers in Cancer Immunotherapy.

Ravindranathan, Deepak, Master, Viraj A, Bilen, Mehmet Asim · 2021 · Biology · DOI

Full title: Inflammatory Markers in Cancer Immunotherapy.

Authors: Ravindranathan, Deepak, Master, Viraj A, Bilen, Mehmet Asim

Year: 2021

Venue: Biology

DOI: https://doi.org/10.3390/biology10040325

Paper The safety and tolerability of combined immune checkpoint inhibitors (anti-PD-1/PD-L1 plus anti-CTLA-4): a systematic review and meta-analysis.

Gu, Lihu, Khadaroo, Parikshit Asutosh, Su, Hui, Kong, Liya, Chen, Liangliang, Wang, Xianfa, Li, Xinlong, Zhu, Hepan, Zhong, Xin, Pan, Junhai, Chen, Manman · 2019 · BMC cancer · DOI

Full title: The safety and tolerability of combined immune checkpoint inhibitors (anti-PD-1/PD-L1 plus anti-CTLA-4): a systematic review and meta-analysis.

Authors: Gu, Lihu, Khadaroo, Parikshit Asutosh, Su, Hui, Kong, Liya, Chen, Liangliang, Wang, Xianfa, Li, Xinlong, Zhu, Hepan, Zhong, Xin, Pan, Junhai, Chen, Manman

Year: 2019

Venue: BMC cancer

DOI: https://doi.org/10.1186/s12885-019-5785-z

Paper Comparative efficacy and safety of prolgolimab + nurulimab and nivolumab + ipilimumab in the first-line therapy of metastatic or unresectable melanoma: A systematic review and matching-adjusted indirect comparison

Alexander A. Fedenko, Mariya V. Sedova, A. Kolomeytseva, M. Batov, O. Mironenko, K. V. Sapozhnikov, N. Sableva, A. Lazarev, D. G. Tolkacheva, V. D. Batorova, I. Samoylenko · 2025 · Journal of Modern Oncology · DOI

Full title: Comparative efficacy and safety of prolgolimab + nurulimab and nivolumab + ipilimumab in the first-line therapy of metastatic or unresectable melanoma: A systematic review and matching-adjusted indirect comparison

Authors: Alexander A. Fedenko, Mariya V. Sedova, A. Kolomeytseva, M. Batov, O. Mironenko, K. V. Sapozhnikov, N. Sableva, A. Lazarev, D. G. Tolkacheva, V. D. Batorova, I. Samoylenko

Year: 2025

Venue: Journal of Modern Oncology

DOI: https://doi.org/10.26442/18151434.2025.3.203473

Paper Rationale and Clinical Research Progress on PD-1/PD-L1-Based Immunotherapy for Metastatic Triple-Negative Breast Cancer.

Ren, Yifan, Song, Jialong, Li, Xinyi, Luo, Na · 2022 · International journal of molecular sciences · DOI

Full title: Rationale and Clinical Research Progress on PD-1/PD-L1-Based Immunotherapy for Metastatic Triple-Negative Breast Cancer.

Authors: Ren, Yifan, Song, Jialong, Li, Xinyi, Luo, Na

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms23168878

Paper Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma

Kos, Špela, Lopes, Alessandra, Préat, Véronique, Čemažar, Maja, Tratar, Urša Lampreht, Učakar, Bernard, Vanvarenberg, Kévin, Serša, Gregor, Vandermeulen, Gaëlle · 2019 · PLoS ONE · DOI

Full title: Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma

Authors: Kos, Špela, Lopes, Alessandra, Préat, Véronique, Čemažar, Maja, Tratar, Urša Lampreht, Učakar, Bernard, Vanvarenberg, Kévin, Serša, Gregor, Vandermeulen, Gaëlle

Year: 2019

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0217762

Paper Multi-omics analyses inform mechanisms of immunotherapy response in pancreatic cancer

Meng Wu, Ge Li, Yecheng Li, Kai Chen, Mengdan Xu, Dapeng Li, Caihua Xu, Meng Shen, Wei Li, Jinming Cao · 2025 · Frontiers in Immunology · DOI

Full title: Multi-omics analyses inform mechanisms of immunotherapy response in pancreatic cancer

Authors: Meng Wu, Ge Li, Yecheng Li, Kai Chen, Mengdan Xu, Dapeng Li, Caihua Xu, Meng Shen, Wei Li, Jinming Cao

Year: 2025

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2025.1673098

Paper Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

Roszik, Jason, Haydu, Lauren E, Hess, Kenneth R, Oba, Junna, Joon, Aron Y, Siroy, Alan E, Karpinets, Tatiana V, Stingo, Francesco C, Baladandayuthapani, Veera, Tetzlaff, Michael T, Wargo, Jennifer A, Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L, Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K, Shaw, Kenna R, Mills, Gordon B, Gershenwald, Jeffrey E, Radvanyi, Laszlo G, Hwu, Patrick, Futreal, P Andrew, Gibbons, Don L, Lazar, Alexander J, Bernatchez, Chantale, Davies, Michael A, Woodman, Scott E · 2016 · BMC medicine · DOI

Full title: Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

Authors: Roszik, Jason, Haydu, Lauren E, Hess, Kenneth R, Oba, Junna, Joon, Aron Y, Siroy, Alan E, Karpinets, Tatiana V, Stingo, Francesco C, Baladandayuthapani, Veera, Tetzlaff, Michael T, Wargo, Jennifer A, Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L, Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K, Shaw, Kenna R, Mills, Gordon B, Gershenwald, Jeffrey E, Radvanyi, Laszlo G, Hwu, Patrick, Futreal, P Andrew, Gibbons, Don L, Lazar, Alexander J, Bernatchez, Chantale, Davies, Michael A, Woodman, Scott E

Year: 2016

Venue: BMC medicine

DOI: https://doi.org/10.1186/s12916-016-0705-4

Paper Lymphocyte T Subsets and Outcome of Immune Checkpoint Inhibitors in Melanoma Patients: An Oncologist's Perspective on Current Knowledge.

Martínez-Vila, Clara, González-Navarro, Europa Azucena, Teixido, Cristina, Martin, Roberto, Aya, Francisco, Juan, Manel, Arance, Ana · 2024 · International journal of molecular sciences · DOI

Full title: Lymphocyte T Subsets and Outcome of Immune Checkpoint Inhibitors in Melanoma Patients: An Oncologist's Perspective on Current Knowledge.

Authors: Martínez-Vila, Clara, González-Navarro, Europa Azucena, Teixido, Cristina, Martin, Roberto, Aya, Francisco, Juan, Manel, Arance, Ana

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms25179506

Paper PD-1/PD-L Axis in Neuroinflammation: New Insights.

Manenti, Susanna, Orrico, Mario, Masciocchi, Stefano, Mandelli, Alessandra, Finardi, Annamaria, Furlan, Roberto · 2022 · Frontiers in neurology · DOI

Full title: PD-1/PD-L Axis in Neuroinflammation: New Insights.

Authors: Manenti, Susanna, Orrico, Mario, Masciocchi, Stefano, Mandelli, Alessandra, Finardi, Annamaria, Furlan, Roberto

Year: 2022

Venue: Frontiers in neurology

DOI: https://doi.org/10.3389/fneur.2022.877936

Paper Hallmarks of the Tumour Microenvironment of Gliomas and Its Interaction with Emerging Immunotherapy Modalities

C. Linares, Anjana Varghese, Aruni Ghose, Sayali D. Shinde, S. Adeleke, Elisabet Sánchez, M. Sheriff, Cyrus Chargari, E. Rassy, S. Boussios · 2023 · International Journal of Molecular Sciences · DOI

Full title: Hallmarks of the Tumour Microenvironment of Gliomas and Its Interaction with Emerging Immunotherapy Modalities

Authors: C. Linares, Anjana Varghese, Aruni Ghose, Sayali D. Shinde, S. Adeleke, Elisabet Sánchez, M. Sheriff, Cyrus Chargari, E. Rassy, S. Boussios

Year: 2023

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms241713215

Paper Clinical value of M1 macrophage-related genes identification in bladder urothelial carcinoma and in vitro validation

Yu, Yang, Huang, Yuexi, Li, Chen, Ou, Santao, Xu, Chaojie, Kang, Zhengjun · 2022 · Frontiers in Genetics · DOI

Full title: Clinical value of M1 macrophage-related genes identification in bladder urothelial carcinoma and in vitro validation

Authors: Yu, Yang, Huang, Yuexi, Li, Chen, Ou, Santao, Xu, Chaojie, Kang, Zhengjun

Year: 2022

Venue: Frontiers in Genetics

DOI: https://doi.org/10.3389/fgene.2022.1047004

Paper Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer

Schlick, Brian D., Shields, Misty Dawn, Marin‐Acevedo, Julian A., Patel, Ishika, Pellini, Bruna · 2022 · Current Treatment Options in Oncology · DOI

Full title: Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer

Authors: Schlick, Brian D., Shields, Misty Dawn, Marin‐Acevedo, Julian A., Patel, Ishika, Pellini, Bruna

Year: 2022

Venue: Current Treatment Options in Oncology

DOI: https://doi.org/10.1007/s11864-022-00989-7

Paper Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs

Pantelyushin, Stanislav, Ranninger, Elisabeth, Guerrera, Diego, Hütter, Gregor, Maake, Caroline, Markkanen, Enni, Bettschart‐Wolfensberger, Regula, Bley, Carla Rohrer, Läubli, Heinz, Berg, Johannes vom · 2021 · Cancers · DOI

Full title: Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs

Authors: Pantelyushin, Stanislav, Ranninger, Elisabeth, Guerrera, Diego, Hütter, Gregor, Maake, Caroline, Markkanen, Enni, Bettschart‐Wolfensberger, Regula, Bley, Carla Rohrer, Läubli, Heinz, Berg, Johannes vom

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13040785

Paper Immune checkpoint inhibitors: the new frontier in non&ndash;small cell lung cancer treatment

El‐Osta, Hazem, Shahid, Kamran, Mills, Glenn, Peddi, Prakash · 2016 · OncoTargets and Therapy · DOI

Full title: Immune checkpoint inhibitors: the new frontier in non&ndash;small cell lung cancer treatment

Authors: El‐Osta, Hazem, Shahid, Kamran, Mills, Glenn, Peddi, Prakash

Year: 2016

Venue: OncoTargets and Therapy

DOI: https://doi.org/10.2147/ott.s111209

Paper Immune Checkpoint Inhibitors in Colorectal Cancer: Challenges and Future Prospects.

Makaremi, Shima, Asadzadeh, Zahra, Hemmat, Nima, Baghbanzadeh, Amir, Sgambato, Alessandro, Ghorbaninezhad, Farid, Safarpour, Hossein, Argentiero, Antonella, Brunetti, Oronzo, Bernardini, Renato, Silvestris, Nicola, Baradaran, Behzad · 2021 · Biomedicines · DOI

Full title: Immune Checkpoint Inhibitors in Colorectal Cancer: Challenges and Future Prospects.

Authors: Makaremi, Shima, Asadzadeh, Zahra, Hemmat, Nima, Baghbanzadeh, Amir, Sgambato, Alessandro, Ghorbaninezhad, Farid, Safarpour, Hossein, Argentiero, Antonella, Brunetti, Oronzo, Bernardini, Renato, Silvestris, Nicola, Baradaran, Behzad

Year: 2021

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines9091075

Paper Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment.

Ziogas, Dimitrios C, Theocharopoulos, Charalampos, Lialios, Panagiotis-Petros, Foteinou, Dimitra, Koumprentziotis, Ioannis-Alexios, Xynos, Georgios, Gogas, Helen · 2023 · Cancers · DOI

Full title: Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment.

Authors: Ziogas, Dimitrios C, Theocharopoulos, Charalampos, Lialios, Panagiotis-Petros, Foteinou, Dimitra, Koumprentziotis, Ioannis-Alexios, Xynos, Georgios, Gogas, Helen

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15102718

Paper Investigation of the CTLA-4-CD28 Axis in Oral Squamous Cell Carcinoma.

Feldmeier, Ferdinand, Weber, Manuel, Pacelli, Franca, Vogl, Christoph, Glajzer, Jacek, Trumet, Leah, Buchbender, Mayte, Geppert, Carol, Kesting, Marco, Ries, Jutta · 2025 · Journal of clinical medicine · DOI

Full title: Investigation of the CTLA-4-CD28 Axis in Oral Squamous Cell Carcinoma.

Authors: Feldmeier, Ferdinand, Weber, Manuel, Pacelli, Franca, Vogl, Christoph, Glajzer, Jacek, Trumet, Leah, Buchbender, Mayte, Geppert, Carol, Kesting, Marco, Ries, Jutta

Year: 2025

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm14145171

Paper Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan K., Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Clech, Marine Le, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina · 2020 · Frontiers in Oncology · DOI

Full title: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

Authors: Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan K., Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Clech, Marine Le, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina

Year: 2020

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2020.575737

Paper The clinical promise of immunotherapy in triple-negative breast cancer

Vikas, Praveen, Borcherding, Nicholas, Zhang, Weizhou · 2018 · Cancer Management and Research · DOI

Full title: The clinical promise of immunotherapy in triple-negative breast cancer

Authors: Vikas, Praveen, Borcherding, Nicholas, Zhang, Weizhou

Year: 2018

Venue: Cancer Management and Research

DOI: https://doi.org/10.2147/cmar.s185176

Paper Recent advances in immunotherapy in cancer treatment.

Patel, Ayyub A · 2024 · Cellular and molecular biology (Noisy-le-Grand, France) · DOI

Full title: Recent advances in immunotherapy in cancer treatment.

Authors: Patel, Ayyub A

Year: 2024

Venue: Cellular and molecular biology (Noisy-le-Grand, France)

DOI: https://doi.org/10.14715/cmb/2024.70.5.13

Paper Tertiary lymphoid structures in pancreatic cancer: a new target for immunotherapy

Zou, Xinlei, Guan, Canghai, Gao, Jianjun, Shi, Wujiang, Cui, Yunfu, Zhong, Xiangyu · 2023 · Frontiers in Immunology · DOI

Full title: Tertiary lymphoid structures in pancreatic cancer: a new target for immunotherapy

Authors: Zou, Xinlei, Guan, Canghai, Gao, Jianjun, Shi, Wujiang, Cui, Yunfu, Zhong, Xiangyu

Year: 2023

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2023.1222719

Paper A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review).

Kong, Xianbin, Lu, Peng, Liu, Chuanxin, Guo, Yuzhu, Yang, Yuying, Peng, Yingying, Wang, Fangyuan, Bo, Zhichao, Dou, Xiaoxin, Shi, Haoyang, Meng, Jingyan · 2021 · Molecular medicine reports · DOI

Full title: A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review).

Authors: Kong, Xianbin, Lu, Peng, Liu, Chuanxin, Guo, Yuzhu, Yang, Yuying, Peng, Yingying, Wang, Fangyuan, Bo, Zhichao, Dou, Xiaoxin, Shi, Haoyang, Meng, Jingyan

Year: 2021

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2021.12001

Paper Severe Bone Marrow Hypoplasia in a Combined Treatment with Anti PD 1/CTLA-4 in a Patient with Melanoma: A Case Report and Literature Review

Zoppi, M. · 2022 · Journal of Oncology Research and Therapy · DOI

Full title: Severe Bone Marrow Hypoplasia in a Combined Treatment with Anti PD 1/CTLA-4 in a Patient with Melanoma: A Case Report and Literature Review

Authors: Zoppi, M.

Year: 2022

Venue: Journal of Oncology Research and Therapy

DOI: https://doi.org/10.29011/2574-710x.10138

Paper Novel Immunotherapeutics for the Treatment of Non-Small Cell Lung Cancer (NSCLC) Resistant to PD-1/PD-L1 Inhibitors.

Malhotra, Jyoti, Huang, Amy, Amini, Arya, Lee, Percy · 2024 · Cancers · DOI

Full title: Novel Immunotherapeutics for the Treatment of Non-Small Cell Lung Cancer (NSCLC) Resistant to PD-1/PD-L1 Inhibitors.

Authors: Malhotra, Jyoti, Huang, Amy, Amini, Arya, Lee, Percy

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16213603

Paper Recent Developments in Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative Breast Cancer (TNBC).

Battogtokh, Gantumur, Obidiro, Onyinyechi, Akala, Emmanuel O · 2024 · Cancers · DOI

Full title: Recent Developments in Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative Breast Cancer (TNBC).

Authors: Battogtokh, Gantumur, Obidiro, Onyinyechi, Akala, Emmanuel O

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16112012

Paper New Therapeutic Approaches for Conjunctival Melanoma-What We Know So Far and Where Therapy Is Potentially Heading: Focus on Lymphatic Vessels and Dendritic Cells.

Peil, Jennifer, Bock, Felix, Kiefer, Friedemann, Schmidt, Rebecca, Heindl, Ludwig M, Cursiefen, Claus, Schlereth, Simona L · 2022 · International journal of molecular sciences · DOI

Full title: New Therapeutic Approaches for Conjunctival Melanoma-What We Know So Far and Where Therapy Is Potentially Heading: Focus on Lymphatic Vessels and Dendritic Cells.

Authors: Peil, Jennifer, Bock, Felix, Kiefer, Friedemann, Schmidt, Rebecca, Heindl, Ludwig M, Cursiefen, Claus, Schlereth, Simona L

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms23031478

Paper Development of a Highly Sensitive Hybrid LC/MS Assay for the Quantitative Measurement of CTLA-4 in Human T Cells.

Wei, Dong, Horton, Kristin L, Chen, John, Dong, Linlin, Chen, Susan, Abdul-Hadi, Kojo, Zhang, Ting Ting, Casson, Cierra N, Shaw, Michael, Shiraishi, Tsubasa, Wilkinson, Brandon, Ji, Chengjie, Qian, Mark G · 2023 · Molecules (Basel, Switzerland) · DOI

Full title: Development of a Highly Sensitive Hybrid LC/MS Assay for the Quantitative Measurement of CTLA-4 in Human T Cells.

Authors: Wei, Dong, Horton, Kristin L, Chen, John, Dong, Linlin, Chen, Susan, Abdul-Hadi, Kojo, Zhang, Ting Ting, Casson, Cierra N, Shaw, Michael, Shiraishi, Tsubasa, Wilkinson, Brandon, Ji, Chengjie, Qian, Mark G

Year: 2023

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules28083311

Paper Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model.

Bausart, Mathilde, Vanvarenberg, Kevin, Ucakar, Bernard, Lopes, Alessandra, Vandermeulen, Gaëlle, Malfanti, Alessio, Préat, Véronique · 2022 · Pharmaceutics · DOI

Full title: Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model.

Authors: Bausart, Mathilde, Vanvarenberg, Kevin, Ucakar, Bernard, Lopes, Alessandra, Vandermeulen, Gaëlle, Malfanti, Alessio, Préat, Véronique

Year: 2022

Venue: Pharmaceutics

DOI: https://doi.org/10.3390/pharmaceutics14051025

Paper Иммунотерапия уротелиального рака: реалии и перспективы

M. I. Volkova, Ya. V. Gridneva, A. S. Ol’shanskaya · 2018 · DOI

Full title: Иммунотерапия уротелиального рака: реалии и перспективы

Authors: M. I. Volkova, Ya. V. Gridneva, A. S. Ol’shanskaya

Year: 2018

DOI: https://doi.org/10.17650/1726-9776-2017-13-4-16-24

Paper The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology.

Zhang, Shashuang, Liang, Wenhua, Luo, Lingjie, Sun, Shan, Wang, Feng · 2020 · BMC biology · DOI

Full title: The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology.

Authors: Zhang, Shashuang, Liang, Wenhua, Luo, Lingjie, Sun, Shan, Wang, Feng

Year: 2020

Venue: BMC biology

DOI: https://doi.org/10.1186/s12915-020-00765-9

Paper Efficacy and safety of lenvatinib combined with PD-1/PD-L1 inhibitors plus Gemox chemotherapy in advanced biliary tract cancer.

Zhu, Chengpei, Xue, Jingnan, Wang, Yunchao, Wang, Shanshan, Zhang, Nan, Wang, Yanyu, Zhang, Longhao, Yang, Xu, Long, Junyu, Yang, Xiaobo, Sang, Xinting, Zhao, Haitao · 2023 · Frontiers in immunology · DOI

Full title: Efficacy and safety of lenvatinib combined with PD-1/PD-L1 inhibitors plus Gemox chemotherapy in advanced biliary tract cancer.

Authors: Zhu, Chengpei, Xue, Jingnan, Wang, Yunchao, Wang, Shanshan, Zhang, Nan, Wang, Yanyu, Zhang, Longhao, Yang, Xu, Long, Junyu, Yang, Xiaobo, Sang, Xinting, Zhao, Haitao

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1109292

Paper Moving Immune Checkpoint Inhibitors to Early Non-Small Cell Lung Cancer: A Narrative Review

Viscardi, Giuseppe, Vitiello, Fabiana, Servetto, Alberto, Gristina, Valerio, Pizzutilo, Elio Gregory, Canciello, Maria Anna, Medusa, Paola Maria, Salomone, Fabio, Guida, Gaetano Di, Mollica, Mariano, Aronne, Luigi, Scaramuzzi, Roberto, Napolitano, Filomena, Battiloro, Ciro, Caputo, Francesca, Gilli, Marina, Totaro, Giuseppe, Curcio, Carlo, Rocco, Danilo, Montesarchio, Vincenzo · 2022 · Cancers · DOI

Full title: Moving Immune Checkpoint Inhibitors to Early Non-Small Cell Lung Cancer: A Narrative Review

Authors: Viscardi, Giuseppe, Vitiello, Fabiana, Servetto, Alberto, Gristina, Valerio, Pizzutilo, Elio Gregory, Canciello, Maria Anna, Medusa, Paola Maria, Salomone, Fabio, Guida, Gaetano Di, Mollica, Mariano, Aronne, Luigi, Scaramuzzi, Roberto, Napolitano, Filomena, Battiloro, Ciro, Caputo, Francesca, Gilli, Marina, Totaro, Giuseppe, Curcio, Carlo, Rocco, Danilo, Montesarchio, Vincenzo

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14235810

Paper A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas

Monga, Varun, Skubitz, Keith M., Maliske, Seth, Mott, Sarah L., Dietz, Hilary, Hirbe, Angela C., Tine, Brian A. Van, Oppelt, Peter, Okuno, Scott H., Robinson, Steven I., O’Connor, Madeline, Seetharam, Mahesh, Attia, Steven, Charlson, John A., Agulnik, Mark, Milhem, Mohammed · 2020 · Cancers · DOI

Full title: A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas

Authors: Monga, Varun, Skubitz, Keith M., Maliske, Seth, Mott, Sarah L., Dietz, Hilary, Hirbe, Angela C., Tine, Brian A. Van, Oppelt, Peter, Okuno, Scott H., Robinson, Steven I., O’Connor, Madeline, Seetharam, Mahesh, Attia, Steven, Charlson, John A., Agulnik, Mark, Milhem, Mohammed

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12071873

Paper Clinical Trials of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma.

Dyhl-Polk, Anne, Mikkelsen, Marta Kramer, Ladekarl, Morten, Nielsen, Dorte Lisbet · 2021 · Journal of clinical medicine · DOI

Full title: Clinical Trials of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma.

Authors: Dyhl-Polk, Anne, Mikkelsen, Marta Kramer, Ladekarl, Morten, Nielsen, Dorte Lisbet

Year: 2021

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm10122662

Paper Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients.

Bołkun, Łukasz, Starosz, Aleksandra, Krętowska-Grunwald, Anna, Wasiluk, Tomasz, Walewska, Alicja, Wierzbowska, Agnieszka, Moniuszko, Marcin, Grubczak, Kamil · 2024 · Cancers · DOI

Full title: Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients.

Authors: Bołkun, Łukasz, Starosz, Aleksandra, Krętowska-Grunwald, Anna, Wasiluk, Tomasz, Walewska, Alicja, Wierzbowska, Agnieszka, Moniuszko, Marcin, Grubczak, Kamil

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16020462

Paper Diabetes insipidus: A rare endocrine complication of immune check point inhibitors: A case report and literature review.

Angelousi, Anna, Papalexis, Petros, Karampela, Athina, Marra, Marianna, Misthos, Dimitrios, Ziogas, Dimitrios, Gogas, Helen · 2023 · Experimental and therapeutic medicine · DOI

Full title: Diabetes insipidus: A rare endocrine complication of immune check point inhibitors: A case report and literature review.

Authors: Angelousi, Anna, Papalexis, Petros, Karampela, Athina, Marra, Marianna, Misthos, Dimitrios, Ziogas, Dimitrios, Gogas, Helen

Year: 2023

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2022.11709

Paper Differential Dermatologic Adverse Events Associated With Checkpoint Inhibitor Monotherapy and Combination Therapy: A Meta-Analysis of Randomized Control Trials.

Ge, Yang, Zhang, Huiyun, Weygant, Nathaniel, Yao, Jiannan · 2021 · Frontiers in pharmacology · DOI

Full title: Differential Dermatologic Adverse Events Associated With Checkpoint Inhibitor Monotherapy and Combination Therapy: A Meta-Analysis of Randomized Control Trials.

Authors: Ge, Yang, Zhang, Huiyun, Weygant, Nathaniel, Yao, Jiannan

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.640099

Paper Reprogramming the immunosuppressive breast cancer microenvironment: integrating cellular, metabolic, and stromal targets for rational immunotherapy.

Ma, Chang, Teoh, Hoon Koon, Zhao, Yang, Wang, Yifan, Zhao, Jun, Liu, Yan, Zhao, Chen, Ong, Hooi Tin · 2026 · Frontiers in immunology · DOI

Full title: Reprogramming the immunosuppressive breast cancer microenvironment: integrating cellular, metabolic, and stromal targets for rational immunotherapy.

Authors: Ma, Chang, Teoh, Hoon Koon, Zhao, Yang, Wang, Yifan, Zhao, Jun, Liu, Yan, Zhao, Chen, Ong, Hooi Tin

Year: 2026

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2026.1760782

Paper The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice.

Liang, Leilei, Ge, Keli, Zhang, Fengying, Ge, Yinlin · 2018 · Cellular & molecular biology letters · DOI

Full title: The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice.

Authors: Liang, Leilei, Ge, Keli, Zhang, Fengying, Ge, Yinlin

Year: 2018

Venue: Cellular & molecular biology letters

DOI: https://doi.org/10.1186/s11658-018-0122-0

Paper Medication-associated thyroid eye disease: a review.

Ang, Terence, Almater, Abdullah, Selva, Dinesh · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · DOI

Full title: Medication-associated thyroid eye disease: a review.

Authors: Ang, Terence, Almater, Abdullah, Selva, Dinesh

Year: 2026

Venue: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

DOI: https://doi.org/10.1007/s00417-025-07089-w

Paper The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.

Yang, Hui, Wang, Kunlun, Wang, Tao, Li, Mengxi, Li, Bingxu, Li, Shenglei, Yuan, Ling · 2020 · Frontiers in oncology · DOI

Full title: The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.

Authors: Yang, Hui, Wang, Kunlun, Wang, Tao, Li, Mengxi, Li, Bingxu, Li, Shenglei, Yuan, Ling

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.00300

Paper Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma.

Choi, Jaeyeon, Beaino, Wissam, Fecek, Ronald J, Fabian, Kellsye P L, Laymon, Charles M, Kurland, Brenda F, Storkus, Walter J, Anderson, Carolyn J · 2018 · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · DOI

Full title: Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma.

Authors: Choi, Jaeyeon, Beaino, Wissam, Fecek, Ronald J, Fabian, Kellsye P L, Laymon, Charles M, Kurland, Brenda F, Storkus, Walter J, Anderson, Carolyn J

Year: 2018

Venue: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

DOI: https://doi.org/10.2967/jnumed.118.209510

Paper The use of immunotherapy in the treatment of melanoma.

Achkar, Tala, Tarhini, Ahmad A · 2017 · Journal of hematology & oncology · DOI

Full title: The use of immunotherapy in the treatment of melanoma.

Authors: Achkar, Tala, Tarhini, Ahmad A

Year: 2017

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-017-0458-3

Paper Development of therapeutic antibodies for the treatment of diseases

Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung · 2020 · Journal of Biomedical Science · DOI

Full title: Development of therapeutic antibodies for the treatment of diseases

Authors: Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung

Year: 2020

Venue: Journal of Biomedical Science

DOI: https://doi.org/10.1186/s12929-019-0592-z

Paper Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

Ferrere, Gladys, Tidjani Alou, Maryam, Liu, Peng, Goubet, Anne-Gaëlle, Fidelle, Marine, Kepp, Oliver, Durand, Sylvère, Iebba, Valerio, Fluckiger, Aurélie, Daillère, Romain, Thelemaque, Cassandra, Grajeda-Iglesias, Claudia, Alves Costa Silva, Carolina, Aprahamian, Fanny, Lefevre, Déborah, Zhao, Liwei, Ryffel, Bernhard, Colomba, Emeline, Arnedos, Monica, Drubay, Damien, Rauber, Conrad, Raoult, Didier, Asnicar, Francesco, Spector, Tim, Segata, Nicola, Derosa, Lisa, Kroemer, Guido, Zitvogel, Laurence · 2021 · JCI insight · DOI

Full title: Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

Authors: Ferrere, Gladys, Tidjani Alou, Maryam, Liu, Peng, Goubet, Anne-Gaëlle, Fidelle, Marine, Kepp, Oliver, Durand, Sylvère, Iebba, Valerio, Fluckiger, Aurélie, Daillère, Romain, Thelemaque, Cassandra, Grajeda-Iglesias, Claudia, Alves Costa Silva, Carolina, Aprahamian, Fanny, Lefevre, Déborah, Zhao, Liwei, Ryffel, Bernhard, Colomba, Emeline, Arnedos, Monica, Drubay, Damien, Rauber, Conrad, Raoult, Didier, Asnicar, Francesco, Spector, Tim, Segata, Nicola, Derosa, Lisa, Kroemer, Guido, Zitvogel, Laurence

Year: 2021

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.145207

Paper The Risk Ratio of Immune-Related Colitis, Hepatitis, and Pancreatitis in Patients With Solid Tumors Caused by PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Tian, Yuan, Zhang, Zewen, Yang, Xiaowei, Li, Donghua, Zhang, Li, Li, Zhuoqi, Zhang, Shuisheng, Mao, Yantao, Jin, Chenxing, Zhao, Yi · 2020 · Frontiers in oncology · DOI

Full title: The Risk Ratio of Immune-Related Colitis, Hepatitis, and Pancreatitis in Patients With Solid Tumors Caused by PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Authors: Tian, Yuan, Zhang, Zewen, Yang, Xiaowei, Li, Donghua, Zhang, Li, Li, Zhuoqi, Zhang, Shuisheng, Mao, Yantao, Jin, Chenxing, Zhao, Yi

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.00261

Paper Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.

Sanghera, Chandan, Sanghera, Rohan · 2019 · Cureus · DOI

Full title: Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.

Authors: Sanghera, Chandan, Sanghera, Rohan

Year: 2019

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.5938

Paper Real-World Treatment Patterns and Survival in Uveal Melanoma: A Multicenter Cohort Study by the Turkish Oncology Group (TOG)

On, Sercan, Cebeci, Selin, Turna, Zeynep Hande, Sevgen, Zeynep Gülsüm Güç, Guven, Deniz Can, Kılıçkap, Sadettin, Başer, Mehmet Nuri, Demir, Bilgin, Biter, Sedat, Bayram, Ertuğrul, Yeşilyurt, Berkay, Uncu, Doğan, Arslan, Ahmet Melih, Akyürek, Elif Atağ, Arvas, Hayati, Urakçı, Zuhat, Şakalar, Teoman, Aslan, Ferit, Uzun, Mehmet, Yıldırım, Mustafa, Unlu, Ahmet, Salim, Derya Kıvrak, Erdoğan, Atike Pınar, Sahin, Elif, Gündüz, Şeyda, Gülbağcı, Burcu, Yayla, Şaziye Burçak Karaca, Cakar, Burcu · 2026 · Cancers · DOI

Full title: Real-World Treatment Patterns and Survival in Uveal Melanoma: A Multicenter Cohort Study by the Turkish Oncology Group (TOG)

Authors: On, Sercan, Cebeci, Selin, Turna, Zeynep Hande, Sevgen, Zeynep Gülsüm Güç, Guven, Deniz Can, Kılıçkap, Sadettin, Başer, Mehmet Nuri, Demir, Bilgin, Biter, Sedat, Bayram, Ertuğrul, Yeşilyurt, Berkay, Uncu, Doğan, Arslan, Ahmet Melih, Akyürek, Elif Atağ, Arvas, Hayati, Urakçı, Zuhat, Şakalar, Teoman, Aslan, Ferit, Uzun, Mehmet, Yıldırım, Mustafa, Unlu, Ahmet, Salim, Derya Kıvrak, Erdoğan, Atike Pınar, Sahin, Elif, Gündüz, Şeyda, Gülbağcı, Burcu, Yayla, Şaziye Burçak Karaca, Cakar, Burcu

Year: 2026

Venue: Cancers

DOI: https://doi.org/10.3390/cancers18030394

Paper Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma.

Park, Robin, Eshrat, Fariha, Al-Jumayli, Mohammed, Saeed, Azhar, Saeed, Anwaar · 2020 · Vaccines · DOI

Full title: Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma.

Authors: Park, Robin, Eshrat, Fariha, Al-Jumayli, Mohammed, Saeed, Azhar, Saeed, Anwaar

Year: 2020

Venue: Vaccines

DOI: https://doi.org/10.3390/vaccines8030447

Paper The efficacy of third generation anti‑HER2 chimeric antigen receptor T�cells in combination with PD1 blockade against malignant glioblastoma cells

Shen, Luxi, Li, Hongzhi, Bin, Shufang, Li, Panyuan, Chen, Jie, Gu, Haihua, Yuan, Weihua · 2019 · Oncology Reports · DOI

Full title: The efficacy of third generation anti‑HER2 chimeric antigen receptor T�cells in combination with PD1 blockade against malignant glioblastoma cells

Authors: Shen, Luxi, Li, Hongzhi, Bin, Shufang, Li, Panyuan, Chen, Jie, Gu, Haihua, Yuan, Weihua

Year: 2019

Venue: Oncology Reports

DOI: https://doi.org/10.3892/or.2019.7263

Paper Complete Response Associated With Combination Treatment Regorafenib and Sintilimab in a Sorafenib-refractory Hepatocellular Carcinoma Patient

E. Zhang, Zun-yi Zhang, Lei Zhang, Shuai Xiang, Xiaoping Chen, Zhiyong Huang · 2020 · DOI

Full title: Complete Response Associated With Combination Treatment Regorafenib and Sintilimab in a Sorafenib-refractory Hepatocellular Carcinoma Patient

Authors: E. Zhang, Zun-yi Zhang, Lei Zhang, Shuai Xiang, Xiaoping Chen, Zhiyong Huang

Year: 2020

DOI: https://doi.org/10.21203/rs.3.rs-49286/v1

Paper Case Report: When dual immune checkpoint blockade strikes back: cadonilimab-induced hypersensitivity in solid tumors - a case series and review.

Song, Ping, Jin, Yuqi, Fu, Linglin, Yang, Fengming, Tan, Yinuo · 2025 · Frontiers in immunology · DOI

Full title: Case Report: When dual immune checkpoint blockade strikes back: cadonilimab-induced hypersensitivity in solid tumors - a case series and review.

Authors: Song, Ping, Jin, Yuqi, Fu, Linglin, Yang, Fengming, Tan, Yinuo

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1643279

Paper Editorial: Unveiling the next generation of cancer immunity & immunotherapy.

Sadasivam, Mohanraj, Muniraj, Nethaji, Thangavel, Chellappagounder · 2025 · Frontiers in immunology · DOI

Full title: Editorial: Unveiling the next generation of cancer immunity & immunotherapy.

Authors: Sadasivam, Mohanraj, Muniraj, Nethaji, Thangavel, Chellappagounder

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1769324

Paper Determination of a prediction model for therapeutic response and prognosis based on chemokine signaling-related genes in stage I–III lung squamous cell carcinoma

Jinzhi Lai, Shiyu Yang, Shu-hua Chu, Tianwen Xu, Jingshan Huang · 2022 · Frontiers in Genetics · DOI

Full title: Determination of a prediction model for therapeutic response and prognosis based on chemokine signaling-related genes in stage I–III lung squamous cell carcinoma

Authors: Jinzhi Lai, Shiyu Yang, Shu-hua Chu, Tianwen Xu, Jingshan Huang

Year: 2022

Venue: Frontiers in Genetics

DOI: https://doi.org/10.3389/fgene.2022.921837

Paper The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

Ascierto, Paolo A, Warner, Allison Betof, Blank, Christian, Caracò, Corrado, Demaria, Sandra, Gershenwald, Jeffrey E, Khushalani, Nikhil I, Long, Georgina V, Luke, Jason J, Mehnert, Janice M, Robert, Caroline, Rutkowski, Piotr, Tawbi, Hussein A, Osman, Iman, Puzanov, Igor · 2022 · Journal of translational medicine · DOI

Full title: The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

Authors: Ascierto, Paolo A, Warner, Allison Betof, Blank, Christian, Caracò, Corrado, Demaria, Sandra, Gershenwald, Jeffrey E, Khushalani, Nikhil I, Long, Georgina V, Luke, Jason J, Mehnert, Janice M, Robert, Caroline, Rutkowski, Piotr, Tawbi, Hussein A, Osman, Iman, Puzanov, Igor

Year: 2022

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-022-03406-7

Paper Immunotherapy Updates in Advanced Hepatocellular Carcinoma

Singh, Amisha, Beechinor, Ryan J., Huynh, Jasmine C., Li, Daneng, Dayyani, Farshid, Valerin, Jennifer Brooke, Hendifar, Andrew, Gong, Jun, Cho, May · 2021 · Cancers · DOI

Full title: Immunotherapy Updates in Advanced Hepatocellular Carcinoma

Authors: Singh, Amisha, Beechinor, Ryan J., Huynh, Jasmine C., Li, Daneng, Dayyani, Farshid, Valerin, Jennifer Brooke, Hendifar, Andrew, Gong, Jun, Cho, May

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13092164

Paper Immune Checkpoint Blockade - How Does It Work in Brain Metastases?

Lorger, Mihaela, Andreou, Tereza, Fife, Christopher, James, Fiona · 2019 · Frontiers in molecular neuroscience · DOI

Full title: Immune Checkpoint Blockade - How Does It Work in Brain Metastases?

Authors: Lorger, Mihaela, Andreou, Tereza, Fife, Christopher, James, Fiona

Year: 2019

Venue: Frontiers in molecular neuroscience

DOI: https://doi.org/10.3389/fnmol.2019.00282

Paper Mapping endocrine toxicity spectrum of immune checkpoint inhibitors: a disproportionality analysis using the WHO adverse drug reaction database, VigiBase.

Bai, Xuefeng, Lin, Xiahong, Zheng, Kainan, Chen, Xiaoyu, Wu, Xiaohong, Huang, Yinqiong, Zhuang, Yong · 2020 · Endocrine · DOI

Full title: Mapping endocrine toxicity spectrum of immune checkpoint inhibitors: a disproportionality analysis using the WHO adverse drug reaction database, VigiBase.

Authors: Bai, Xuefeng, Lin, Xiahong, Zheng, Kainan, Chen, Xiaoyu, Wu, Xiaohong, Huang, Yinqiong, Zhuang, Yong

Year: 2020

Venue: Endocrine

DOI: https://doi.org/10.1007/s12020-020-02355-9

Paper Lung Cancer Immunotherapy: Beyond Common Immune Checkpoints Inhibitors.

Catalano, Martina, Shabani, Sonia, Venturini, Jacopo, Ottanelli, Carlotta, Voltolini, Luca, Roviello, Giandomenico · 2022 · Cancers · DOI

Full title: Lung Cancer Immunotherapy: Beyond Common Immune Checkpoints Inhibitors.

Authors: Catalano, Martina, Shabani, Sonia, Venturini, Jacopo, Ottanelli, Carlotta, Voltolini, Luca, Roviello, Giandomenico

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14246145

Paper Combination Immunotherapy Strategies in Breast Cancer

Chun, Brie, Page, David B., McArthur, Heather L. · 2019 · Current Breast Cancer Reports · DOI

Full title: Combination Immunotherapy Strategies in Breast Cancer

Authors: Chun, Brie, Page, David B., McArthur, Heather L.

Year: 2019

Venue: Current Breast Cancer Reports

DOI: https://doi.org/10.1007/s12609-019-00333-3

Paper Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medicare Advantage patients.

Gunturu, Krishna S, Pham, Timothy T, Shambhu, Sonali, Fisch, Michael J, Barron, John J, Debono, David · 2022 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · DOI

Full title: Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medicare Advantage patients.

Authors: Gunturu, Krishna S, Pham, Timothy T, Shambhu, Sonali, Fisch, Michael J, Barron, John J, Debono, David

Year: 2022

Venue: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

DOI: https://doi.org/10.1007/s00520-022-06826-9

Paper Next-Generation Immunotherapies to Improve Anticancer Immunity.

Shi, Yaoyao, Tomczak, Katarzyna, Li, June, Ochieng, Joshua K, Lee, Younghee, Haymaker, Cara · 2020 · Frontiers in pharmacology · DOI

Full title: Next-Generation Immunotherapies to Improve Anticancer Immunity.

Authors: Shi, Yaoyao, Tomczak, Katarzyna, Li, June, Ochieng, Joshua K, Lee, Younghee, Haymaker, Cara

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.566401

Paper Mechanisms of resistance to immune checkpoint inhibitors

Jenkins, Russell W., Barbie, David A., Flaherty, Keith T. · 2018 · British Journal of Cancer · DOI

Full title: Mechanisms of resistance to immune checkpoint inhibitors

Authors: Jenkins, Russell W., Barbie, David A., Flaherty, Keith T.

Year: 2018

Venue: British Journal of Cancer

DOI: https://doi.org/10.1038/bjc.2017.434

Paper Endocrine Side Effects in Patients Treated with Immune Checkpoint Inhibitors: A Narrative Review.

Profili, Nicia I, Castelli, Roberto, Gidaro, Antonio, Merella, Alessandro, Manetti, Roberto, Palmieri, Giuseppe, Maioli, Margherita, Delitala, Alessandro P · 2023 · Journal of clinical medicine · DOI

Full title: Endocrine Side Effects in Patients Treated with Immune Checkpoint Inhibitors: A Narrative Review.

Authors: Profili, Nicia I, Castelli, Roberto, Gidaro, Antonio, Merella, Alessandro, Manetti, Roberto, Palmieri, Giuseppe, Maioli, Margherita, Delitala, Alessandro P

Year: 2023

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm12155161

Paper Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.

Turbitt, William J, Orlandella, Rachael M, Gibson, Justin T, Peterson, Courtney M, Norian, Lyse A · 2020 · Anticancer research · DOI

Full title: Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.

Authors: Turbitt, William J, Orlandella, Rachael M, Gibson, Justin T, Peterson, Courtney M, Norian, Lyse A

Year: 2020

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.14555

Paper Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series.

Arora, Puja, Talamo, Laura, Dillon, Patrick, Gentzler, Ryan D, Millard, Trish, Salerno, Michael, Slingluff, Craig L, Gaughan, Elizabeth M · 2020 · Cardio-oncology (London, England) · DOI

Full title: Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series.

Authors: Arora, Puja, Talamo, Laura, Dillon, Patrick, Gentzler, Ryan D, Millard, Trish, Salerno, Michael, Slingluff, Craig L, Gaughan, Elizabeth M

Year: 2020

Venue: Cardio-oncology (London, England)

DOI: https://doi.org/10.1186/s40959-020-00076-6

Paper Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.

Gombos, Randi B, Gonzalez, Ana, Manrique, Mariana, Chand, Dhan, Savitsky, David, Morin, Benjamin, Breous-Nystrom, Ekaterina, Dupont, Christopher, Ward, Rebecca A, Mundt, Cornelia, Duckless, Benjamin, Tang, Hao, Findeis, Mark A, Schuster, Andrea, Waight, Jeremy D, Underwood, Dennis, Clarke, Christopher, Ritter, Gerd, Merghoub, Taha, Schaer, David, Wolchok, Jedd D, van Dijk, Marc, Buell, Jennifer S, Cuillerot, Jean-Marie, Stein, Robert, Drouin, Elise E, Wilson, Nicholas S · 2018 · PloS one · DOI

Full title: Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.

Authors: Gombos, Randi B, Gonzalez, Ana, Manrique, Mariana, Chand, Dhan, Savitsky, David, Morin, Benjamin, Breous-Nystrom, Ekaterina, Dupont, Christopher, Ward, Rebecca A, Mundt, Cornelia, Duckless, Benjamin, Tang, Hao, Findeis, Mark A, Schuster, Andrea, Waight, Jeremy D, Underwood, Dennis, Clarke, Christopher, Ritter, Gerd, Merghoub, Taha, Schaer, David, Wolchok, Jedd D, van Dijk, Marc, Buell, Jennifer S, Cuillerot, Jean-Marie, Stein, Robert, Drouin, Elise E, Wilson, Nicholas S

Year: 2018

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0191926

Paper Immune checkpoint-targeted antibodies: a room for dose and schedule optimization?

Maritaz, Christophe, Broutin, Sophie, Chaput, Nathalie, Marabelle, Aurélien, Paci, Angelo · 2022 · Journal of hematology & oncology · DOI

Full title: Immune checkpoint-targeted antibodies: a room for dose and schedule optimization?

Authors: Maritaz, Christophe, Broutin, Sophie, Chaput, Nathalie, Marabelle, Aurélien, Paci, Angelo

Year: 2022

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-021-01182-3

Paper Immune-related cardiovascular toxicities of PD-1/PD-L1 inhibitors in solid tumors: an updated systematic review and meta-analysis.

Zhang, Chi, Wei, Fengtao, Ma, Wenhan, Zhang, Jingbo · 2024 · Frontiers in immunology · DOI

Full title: Immune-related cardiovascular toxicities of PD-1/PD-L1 inhibitors in solid tumors: an updated systematic review and meta-analysis.

Authors: Zhang, Chi, Wei, Fengtao, Ma, Wenhan, Zhang, Jingbo

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1255825

Paper Comparative Risk of Renal Adverse Events in Patients Receiving Immune Checkpoint Inhibitors: A Bayesian Network Meta-Analysis.

Liu, Kang, Qin, Zhongke, Xu, Xueqiang, Li, Ting, Ge, Yifei, Mao, Huijuan, Xing, Changying · 2021 · Frontiers in oncology · DOI

Full title: Comparative Risk of Renal Adverse Events in Patients Receiving Immune Checkpoint Inhibitors: A Bayesian Network Meta-Analysis.

Authors: Liu, Kang, Qin, Zhongke, Xu, Xueqiang, Li, Ting, Ge, Yifei, Mao, Huijuan, Xing, Changying

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.662731

Paper CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Skoulidis, Ferdinandos, Araújo, Haniel A., Truong, Minh, Qian, Yu, Sun, Xin, Cobo, Ana Galan, Le, John T., Montesion, Meagan, Palmer, Rachael, Jahchan, Nadine S., Juan, Joseph, Min, Chengyin, Yu, Yi, Pan, Xuewen, Arbour, Kathryn C., Vokes, Natalie I., Schmidt, Stephanie, Molkentine, David, Owen, Dwight H., Memmott, Regan, Patil, Pradnya D., Marmarelis, Melina E., Awad, Mark M., Murray, Joseph C., Hellyer, Jessica A., Gainor, Justin F., Dimou, Anastasios, Bestvina, Christine M., Shu, Catherine A., Riess, Jonathan W., Blakely, Collin M., Pecot, Chad V., Mezquita, Laura, Tabbò, Fabrizio, Scheffler, Matthias, Digumarthy, Subba R., Mooradian, Meghan J., Sacher, Adrian G., Lau, Sally C. M., Saltos, Andreas, Rotow, Julia, Johnson, Rocio Perez, Liu, Corinne, Stewart, Tyler F., Goldberg, Sarah B., Killam, Jonathan, Walther, Zenta, Schalper, Kurt A., Davies, Kurtis D., Woodcock, Mark G., Anagnostou, Valsamo, Marrone, Kristen A., Forde, Patrick M., Ricciuti, Biagio, Venkatraman, Deepti, Allen, Eliezer M. Van, Cummings, Amy L., Goldman, Jonathan W., Shaish, Hiram, Kier, Melanie Wain, Katz, Sharyn I., Aggarwal, Charu C., Ni, Ying, Azok, Joseph T., Segal, Jeremy, Ritterhouse, Lauren L., Neal, Joel W., Lacroix, Ludovic, Elamin, Yasir Y., Negrão, Marcelo V., Le, Xiuning, Lam, Vincent K., Lewis, Whitney E., Kemp, Haley N., Carter, Brett, Roth, Jack A., Swisher, Stephen G., Lee, Richard, Zhou, Teng, Poteete, Alissa, Kong, Yifan, Takehara, Tomohiro, Paula, Alvaro Guimaraes, Parra, Edwin R., Behrens, Carmen, Wistuba, Ignacio I., Zhang, Jianjun, Blumenschein, George R., Gay, Carl M., Byers, Lauren A., Gibbons, Don L., Tsao, Anne S., Lee, J. Jack, Bivona, Trever G., Camidge, D. Ross, Gray, Jhannelle E, Lieghl, Natasha, Levy, Benjamin, Brahmer, Julie R., Garassino, Marina Chiara · 2024 · Nature · DOI

Full title: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Authors: Skoulidis, Ferdinandos, Araújo, Haniel A., Truong, Minh, Qian, Yu, Sun, Xin, Cobo, Ana Galan, Le, John T., Montesion, Meagan, Palmer, Rachael, Jahchan, Nadine S., Juan, Joseph, Min, Chengyin, Yu, Yi, Pan, Xuewen, Arbour, Kathryn C., Vokes, Natalie I., Schmidt, Stephanie, Molkentine, David, Owen, Dwight H., Memmott, Regan, Patil, Pradnya D., Marmarelis, Melina E., Awad, Mark M., Murray, Joseph C., Hellyer, Jessica A., Gainor, Justin F., Dimou, Anastasios, Bestvina, Christine M., Shu, Catherine A., Riess, Jonathan W., Blakely, Collin M., Pecot, Chad V., Mezquita, Laura, Tabbò, Fabrizio, Scheffler, Matthias, Digumarthy, Subba R., Mooradian, Meghan J., Sacher, Adrian G., Lau, Sally C. M., Saltos, Andreas, Rotow, Julia, Johnson, Rocio Perez, Liu, Corinne, Stewart, Tyler F., Goldberg, Sarah B., Killam, Jonathan, Walther, Zenta, Schalper, Kurt A., Davies, Kurtis D., Woodcock, Mark G., Anagnostou, Valsamo, Marrone, Kristen A., Forde, Patrick M., Ricciuti, Biagio, Venkatraman, Deepti, Allen, Eliezer M. Van, Cummings, Amy L., Goldman, Jonathan W., Shaish, Hiram, Kier, Melanie Wain, Katz, Sharyn I., Aggarwal, Charu C., Ni, Ying, Azok, Joseph T., Segal, Jeremy, Ritterhouse, Lauren L., Neal, Joel W., Lacroix, Ludovic, Elamin, Yasir Y., Negrão, Marcelo V., Le, Xiuning, Lam, Vincent K., Lewis, Whitney E., Kemp, Haley N., Carter, Brett, Roth, Jack A., Swisher, Stephen G., Lee, Richard, Zhou, Teng, Poteete, Alissa, Kong, Yifan, Takehara, Tomohiro, Paula, Alvaro Guimaraes, Parra, Edwin R., Behrens, Carmen, Wistuba, Ignacio I., Zhang, Jianjun, Blumenschein, George R., Gay, Carl M., Byers, Lauren A., Gibbons, Don L., Tsao, Anne S., Lee, J. Jack, Bivona, Trever G., Camidge, D. Ross, Gray, Jhannelle E, Lieghl, Natasha, Levy, Benjamin, Brahmer, Julie R., Garassino, Marina Chiara

Year: 2024

Venue: Nature

DOI: https://doi.org/10.1038/s41586-024-07943-7

Paper Exploiting Human NK Cells in Tumor Therapy.

Vacca, Paola, Pietra, Gabriella, Tumino, Nicola, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo · 2019 · Frontiers in immunology · DOI

Full title: Exploiting Human NK Cells in Tumor Therapy.

Authors: Vacca, Paola, Pietra, Gabriella, Tumino, Nicola, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo

Year: 2019

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2019.03013

Paper Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma

M. Tucker, L. Brown, Yu-Wei Chen, Chester Kao, Nathan Hirshman, E. Kinsey, K. Ancell, Kathryn E. Beckermann, N. Davis, Renee McAlister, K. Schaffer, A. Armstrong, M. Harrison, D. George, W. Rathmell, B. Rini, Tian Zhang · 2021 · Biomarker Research · DOI

Full title: Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma

Authors: M. Tucker, L. Brown, Yu-Wei Chen, Chester Kao, Nathan Hirshman, E. Kinsey, K. Ancell, Kathryn E. Beckermann, N. Davis, Renee McAlister, K. Schaffer, A. Armstrong, M. Harrison, D. George, W. Rathmell, B. Rini, Tian Zhang

Year: 2021

Venue: Biomarker Research

DOI: https://doi.org/10.1186/s40364-021-00334-4

Paper T-cell-based Immunotherapies for Haematological Cancers, Part A: A SWOT Analysis of Immune Checkpoint Inhibitors (ICIs) and Bispecific T-Cell Engagers (BiTEs).

Rallis, Kathrine S, Hillyar, Christopher R T, Sideris, Michail, Davies, Jeff K · 2021 · Anticancer research · DOI

Full title: T-cell-based Immunotherapies for Haematological Cancers, Part A: A SWOT Analysis of Immune Checkpoint Inhibitors (ICIs) and Bispecific T-Cell Engagers (BiTEs).

Authors: Rallis, Kathrine S, Hillyar, Christopher R T, Sideris, Michail, Davies, Jeff K

Year: 2021

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.14870

Paper Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.

Maines, Lynn W, Keller, Staci N, Smith, Ryan A, Schrecengost, Randy S, Smith, Charles D · 2024 · Cancers · DOI

Full title: Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.

Authors: Maines, Lynn W, Keller, Staci N, Smith, Ryan A, Schrecengost, Randy S, Smith, Charles D

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16091779

Paper Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies.

Golay, Josée, Andrea, Alain E · 2020 · Antibodies (Basel, Switzerland) · DOI

Full title: Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies.

Authors: Golay, Josée, Andrea, Alain E

Year: 2020

Venue: Antibodies (Basel, Switzerland)

DOI: https://doi.org/10.3390/antib9020017

Paper Results from a Meta-analysis of Combination of PD-1/PD-L1 and CTLA-4 Inhibitors in Malignant Cancer Patients: Does PD-L1 Matter?

Feng, Yuqian, Jin, Huimin, Guo, Kaibo, Xiang, Yuying, Zhang, Yiting, Du, Wurong, Shen, Minhe, Ruan, Shanming · 2021 · Frontiers in pharmacology · DOI

Full title: Results from a Meta-analysis of Combination of PD-1/PD-L1 and CTLA-4 Inhibitors in Malignant Cancer Patients: Does PD-L1 Matter?

Authors: Feng, Yuqian, Jin, Huimin, Guo, Kaibo, Xiang, Yuying, Zhang, Yiting, Du, Wurong, Shen, Minhe, Ruan, Shanming

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.572845

Paper Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging.

Tran, Renee L, Liang, Xiaofei, de la Cerda, Jorge, Schuler, F William, Pagel, Mark D · 2025 · Scientific reports · DOI

Full title: Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging.

Authors: Tran, Renee L, Liang, Xiaofei, de la Cerda, Jorge, Schuler, F William, Pagel, Mark D

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-05930-0

Paper Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report.

Zhao, Jiayu, Li, Xiaoxiao, Sun, Xiaoyuan, Xiao, Ruoxi, Xue, Juan, Sui, Kexin, Liu, Zimin · 2025 · Frontiers in immunology · DOI

Full title: Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report.

Authors: Zhao, Jiayu, Li, Xiaoxiao, Sun, Xiaoyuan, Xiao, Ruoxi, Xue, Juan, Sui, Kexin, Liu, Zimin

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1533700

Paper Success of Checkpoint Blockade Paves the Way for Novel Immune Therapy in Malignant Pleural Mesothelioma.

Rondon, Lizbeth, Fu, Roberto, Patel, Manish R · 2023 · Cancers · DOI

Full title: Success of Checkpoint Blockade Paves the Way for Novel Immune Therapy in Malignant Pleural Mesothelioma.

Authors: Rondon, Lizbeth, Fu, Roberto, Patel, Manish R

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15112940

Paper Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors

Salewski, Inken, Kuntoff, Steffen, Kuemmel, Andreas, Feldtmann, Rico, Felix, Stephan B., Henze, Larissa, Junghanß, Christian, Maletzki, Claudia · 2021 · Cancer Immunology Immunotherapy · DOI

Full title: Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors

Authors: Salewski, Inken, Kuntoff, Steffen, Kuemmel, Andreas, Feldtmann, Rico, Felix, Stephan B., Henze, Larissa, Junghanß, Christian, Maletzki, Claudia

Year: 2021

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-021-02933-4

Paper Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report.

Meyers, D E, Hill, W F, Suo, A, Jimenez-Zepeda, V, Cheng, T, Nixon, N A · 2018 · Experimental hematology & oncology · DOI

Full title: Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report.

Authors: Meyers, D E, Hill, W F, Suo, A, Jimenez-Zepeda, V, Cheng, T, Nixon, N A

Year: 2018

Venue: Experimental hematology & oncology

DOI: https://doi.org/10.1186/s40164-018-0098-5

Paper Immune Checkpoint Inhibitors in the Treatment of HCC.

Donisi, Clelia, Puzzoni, Marco, Ziranu, Pina, Lai, Eleonora, Mariani, Stefano, Saba, Giorgio, Impera, Valentino, Dubois, Marco, Persano, Mara, Migliari, Marco, Pretta, Andrea, Liscia, Nicole, Astara, Giorgio, Scartozzi, Mario · 2020 · Frontiers in oncology · DOI

Full title: Immune Checkpoint Inhibitors in the Treatment of HCC.

Authors: Donisi, Clelia, Puzzoni, Marco, Ziranu, Pina, Lai, Eleonora, Mariani, Stefano, Saba, Giorgio, Impera, Valentino, Dubois, Marco, Persano, Mara, Migliari, Marco, Pretta, Andrea, Liscia, Nicole, Astara, Giorgio, Scartozzi, Mario

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.601240

Paper The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

John, Peter, Pulanco, Marc C., Galbo, Phillip M., Yao, Wei, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing · 2022 · Nature Communications · DOI

Full title: The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

Authors: John, Peter, Pulanco, Marc C., Galbo, Phillip M., Yao, Wei, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing

Year: 2022

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-022-30143-8

Paper Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

Liu, Shaokun, Wang, Ru, Fang, Jugao · 2024 · Discover Oncology · DOI

Full title: Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

Authors: Liu, Shaokun, Wang, Ru, Fang, Jugao

Year: 2024

Venue: Discover Oncology

DOI: https://doi.org/10.1007/s12672-024-00870-z

Paper Unveiling the Etiopathogenic Spectrum of Hypophysitis: A Narrative Review.

Menotti, Sara, Giampietro, Antonella, Raia, Salvatore, Veleno, Miriam, Angelini, Flavia, Tartaglione, Tommaso, Gaudino, Simona, Doglietto, Francesco, De Marinis, Laura, Pontecorvi, Alfredo, Bianchi, Antonio, Chiloiro, Sabrina · 2023 · Journal of personalized medicine · DOI

Full title: Unveiling the Etiopathogenic Spectrum of Hypophysitis: A Narrative Review.

Authors: Menotti, Sara, Giampietro, Antonella, Raia, Salvatore, Veleno, Miriam, Angelini, Flavia, Tartaglione, Tommaso, Gaudino, Simona, Doglietto, Francesco, De Marinis, Laura, Pontecorvi, Alfredo, Bianchi, Antonio, Chiloiro, Sabrina

Year: 2023

Venue: Journal of personalized medicine

DOI: https://doi.org/10.3390/jpm13081210

Paper Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Kroon, Paula, Gadiot, Jules, Peeters, Marlies, Gasparini, Alessia, Deken, Marcel A, Yagita, Hideo, Verheij, Marcel, Borst, Jannie, Blank, Christian U, Verbrugge, Inge · 2016 · Cancer immunology, immunotherapy : CII · DOI

Full title: Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Authors: Kroon, Paula, Gadiot, Jules, Peeters, Marlies, Gasparini, Alessia, Deken, Marcel A, Yagita, Hideo, Verheij, Marcel, Borst, Jannie, Blank, Christian U, Verbrugge, Inge

Year: 2016

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-016-1843-4

Paper Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET

J. Schwenck, B. Schörg, F. Fiz, D. Sonanini, A. Forschner, T. Eigentler, B. Weide, M. Martella, I. González-Menéndez, C. Campi, G. Sambuceti, F. Seith, L. Quintanilla‐Martinez, C. Garbe, C. Pfannenberg, M. Röcken, C. la Fougère, B. Pichler, M. Kneilling · 2020 · Theranostics · DOI

Full title: Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET

Authors: J. Schwenck, B. Schörg, F. Fiz, D. Sonanini, A. Forschner, T. Eigentler, B. Weide, M. Martella, I. González-Menéndez, C. Campi, G. Sambuceti, F. Seith, L. Quintanilla‐Martinez, C. Garbe, C. Pfannenberg, M. Röcken, C. la Fougère, B. Pichler, M. Kneilling

Year: 2020

Venue: Theranostics

DOI: https://doi.org/10.7150/thno.35989

Paper Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.

McGinnis, Gwendolyn J, Friedman, David, Young, Kristina H, Torres, Eileen Ruth S, Thomas, Charles R, Gough, Michael J, Raber, Jacob · 2017 · Oncotarget · DOI

Full title: Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.

Authors: McGinnis, Gwendolyn J, Friedman, David, Young, Kristina H, Torres, Eileen Ruth S, Thomas, Charles R, Gough, Michael J, Raber, Jacob

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.13551

Paper Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.

Haibe, Yolla, El Husseini, Ziad, El Sayed, Rola, Shamseddine, Ali · 2020 · International journal of molecular sciences · DOI

Full title: Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.

Authors: Haibe, Yolla, El Husseini, Ziad, El Sayed, Rola, Shamseddine, Ali

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21176176

Paper [Clinical practice and mechanism of endocrinological adverse events associated with immune checkpoint inhibitors].

Iwama, Shintaro, Arima, Hiroshi · 2017 · Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology · DOI

Full title: [Clinical practice and mechanism of endocrinological adverse events associated with immune checkpoint inhibitors].

Authors: Iwama, Shintaro, Arima, Hiroshi

Year: 2017

Venue: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology

DOI: https://doi.org/10.2177/jsci.40.90

Paper Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma

Xuejie Yang, Xiaoqian Yu, H. Nie, Wenying Jiang, Jian-hua Zhou, Chunlin Ou, Xiaoyun He · 2023 · Journal of Cancer · DOI

Full title: Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma

Authors: Xuejie Yang, Xiaoqian Yu, H. Nie, Wenying Jiang, Jian-hua Zhou, Chunlin Ou, Xiaoyun He

Year: 2023

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.87590

Paper Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.

Tao, Hua, Qian, Pudong, Wang, Feijiang, Yu, Hongliang, Guo, Yesong · 2017 · Oncology research · DOI

Full title: Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.

Authors: Tao, Hua, Qian, Pudong, Wang, Feijiang, Yu, Hongliang, Guo, Yesong

Year: 2017

Venue: Oncology research

DOI: https://doi.org/10.3727/096504017X14900505020895

Paper Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors.

Chong, Pei Pei, Rubin, Joshua B, Abdullah, Maha, Conforti, Fabio, Klein, Sabra L, Liu, Wanli · 2022 · Frontiers in immunology · DOI

Full title: Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors.

Authors: Chong, Pei Pei, Rubin, Joshua B, Abdullah, Maha, Conforti, Fabio, Klein, Sabra L, Liu, Wanli

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.941254

Paper CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis.

Ma, Bing, Kamle, Suchitra, Akosman, Bedia, Khan, Hina, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A · 2022 · Frontiers in immunology · DOI

Full title: CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis.

Authors: Ma, Bing, Kamle, Suchitra, Akosman, Bedia, Khan, Hina, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.1056397

Paper Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors.

Zoi, Vasiliki, Galani, Vasiliki, Sioka, Chrissa, Alexiou, Georgios A, Kyritsis, Athanassios P · 2025 · Cancers · DOI

Full title: Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors.

Authors: Zoi, Vasiliki, Galani, Vasiliki, Sioka, Chrissa, Alexiou, Georgios A, Kyritsis, Athanassios P

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17233777

Paper The multidimensional regulatory network of the PD-1/PD-L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyu Lai, Lu Qi, Zhixuan Lin, Zhong Li · 2025 · Oncology Report · DOI

Full title: The multidimensional regulatory network of the PD-1/PD-L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Authors: Haoyu Lai, Lu Qi, Zhixuan Lin, Zhong Li

Year: 2025

Venue: Oncology Report

DOI: https://doi.org/10.3892/or.2025.9021

Paper Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors.

Oh, Chang-Myung, Chon, Hong Jae, Kim, Chan · 2020 · International journal of molecular sciences · DOI

Full title: Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors.

Authors: Oh, Chang-Myung, Chon, Hong Jae, Kim, Chan

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21207743

Paper Immunotherapy in Breast Cancer: the New Frontier.

Hu, Zishuo I, McArthur, Heather L · 2018 · Current breast cancer reports · DOI

Full title: Immunotherapy in Breast Cancer: the New Frontier.

Authors: Hu, Zishuo I, McArthur, Heather L

Year: 2018

Venue: Current breast cancer reports

DOI: https://doi.org/10.1007/s12609-018-0274-y

Paper Hyaluronidase Enhances Targeting of Hydrogel-Encapsulated Anti-CTLA-4 to Tumor Draining Lymph Nodes and Improves Anti-Tumor Efficacy.

Harui, Airi, Roth, Michael D · 2022 · Gels (Basel, Switzerland) · DOI

Full title: Hyaluronidase Enhances Targeting of Hydrogel-Encapsulated Anti-CTLA-4 to Tumor Draining Lymph Nodes and Improves Anti-Tumor Efficacy.

Authors: Harui, Airi, Roth, Michael D

Year: 2022

Venue: Gels (Basel, Switzerland)

DOI: https://doi.org/10.3390/gels8050284

Paper Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy

Mandy van Gulijk, Floris Dammeijer, J. Aerts, H. Vroman · 2018 · Frontiers in Immunology · DOI

Full title: Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy

Authors: Mandy van Gulijk, Floris Dammeijer, J. Aerts, H. Vroman

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.02759

Paper Treatment-Related Adverse Events of Combination Immune Checkpoint Inhibitors: Systematic Review and Meta-Analysis.

Park, Robin, Lopes, Laercio, Cristancho, Cagney R, Riano, Ivy M, Saeed, Anwaar · 2020 · Frontiers in oncology · DOI

Full title: Treatment-Related Adverse Events of Combination Immune Checkpoint Inhibitors: Systematic Review and Meta-Analysis.

Authors: Park, Robin, Lopes, Laercio, Cristancho, Cagney R, Riano, Ivy M, Saeed, Anwaar

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.00258

Paper High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model.

Yamamoto, Junya, Takahashi, Yutaka, Minami, Kazumasa, Tamari, Keisuke, Katsuki, Shohei, Takenaka, Wataru, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko · 2022 · Cancers · DOI

Full title: High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model.

Authors: Yamamoto, Junya, Takahashi, Yutaka, Minami, Kazumasa, Tamari, Keisuke, Katsuki, Shohei, Takenaka, Wataru, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko

Year: 2022

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14092087

Paper PD-1/PD-L1 Inhibitor - Related Adverse Events and Their Management in Breast Cancer.

Lei, Chuqi, Kong, Xiangyi, Li, Yuan, Yang, Huaiyu, Zhang, Ke, Wang, Zhongzhao, Chang, Hu, Xuan, Lixue · 2024 · Journal of Cancer · DOI

Full title: PD-1/PD-L1 Inhibitor - Related Adverse Events and Their Management in Breast Cancer.

Authors: Lei, Chuqi, Kong, Xiangyi, Li, Yuan, Yang, Huaiyu, Zhang, Ke, Wang, Zhongzhao, Chang, Hu, Xuan, Lixue

Year: 2024

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.85433

Paper Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.

Zhang, Zhen, Rafei-Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, Rebecca, Huzly, Daniela, Pinato, David J, Thimme, Robert, Meiss, Frank, Bengsch, Bertram · 2022 · Journal of translational medicine · DOI

Full title: Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.

Authors: Zhang, Zhen, Rafei-Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, Rebecca, Huzly, Daniela, Pinato, David J, Thimme, Robert, Meiss, Frank, Bengsch, Bertram

Year: 2022

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-022-03755-3

Paper Immune Blockade Inhibition in Breast Cancer.

Voutsadakis, Ioannis A · 2016 · Anticancer research · DOI

Full title: Immune Blockade Inhibition in Breast Cancer.

Authors: Voutsadakis, Ioannis A

Year: 2016

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.11145

Paper Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.

Lim, Sung Won, Ahn, Myung-Ju · 2019 · The Korean journal of internal medicine · DOI

Full title: Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.

Authors: Lim, Sung Won, Ahn, Myung-Ju

Year: 2019

Venue: The Korean journal of internal medicine

DOI: https://doi.org/10.3904/kjim.2018.179

Paper Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma

Sadagopan, Narayanan, He, Aiwu Ruth · 2024 · International Journal of Molecular Sciences · DOI

Full title: Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma

Authors: Sadagopan, Narayanan, He, Aiwu Ruth

Year: 2024

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms25021259

Paper - **Authors:** Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir - **Year:** 2025 - **Journal:** Tumor Discovery - **Source:** openalex

Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir · 2025 · Tumor Discovery · DOI

Full title: - **Authors:** Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir - **Year:** 2025 - **Journal:** Tumor Discovery - **Source:** openalex

Authors: Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir

Year: 2025

Venue: Tumor Discovery

DOI: https://doi.org/10.36922/td025320076

Paper Immunotherapy in Advanced Lung Cancer Treatment

A. Grigorescu · 2018 · Lung Cancer · DOI

Full title: Immunotherapy in Advanced Lung Cancer Treatment

Authors: A. Grigorescu

Year: 2018

Venue: Lung Cancer

DOI: https://doi.org/10.5772/intechopen.77005

Paper Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review.

Kovács, Szonja Anna, Győrffy, Balázs · 2022 · Journal of translational medicine · DOI

Full title: Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review.

Authors: Kovács, Szonja Anna, Győrffy, Balázs

Year: 2022

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-022-03409-4

Paper Clinical benefits of PD-1/PD-L1 inhibitors in patients with metastatic colorectal cancer: a systematic review and meta-analysis.

Zhang, Xiao, Yang, Zhengyang, An, Yongbo, Liu, Yishan, Wei, Qi, Xu, Fengming, Yao, Hongwei, Zhang, Zhongtao · 2022 · World journal of surgical oncology · DOI

Full title: Clinical benefits of PD-1/PD-L1 inhibitors in patients with metastatic colorectal cancer: a systematic review and meta-analysis.

Authors: Zhang, Xiao, Yang, Zhengyang, An, Yongbo, Liu, Yishan, Wei, Qi, Xu, Fengming, Yao, Hongwei, Zhang, Zhongtao

Year: 2022

Venue: World journal of surgical oncology

DOI: https://doi.org/10.1186/s12957-022-02549-7

Paper Immunological Agents Used in Cancer Treatment.

Simsek, Melih, Tekin, Salim Basol, Bilici, Mehmet · 2019 · The Eurasian journal of medicine · DOI

Full title: Immunological Agents Used in Cancer Treatment.

Authors: Simsek, Melih, Tekin, Salim Basol, Bilici, Mehmet

Year: 2019

Venue: The Eurasian journal of medicine

DOI: https://doi.org/10.5152/eurasianjmed.2018.18194

Paper Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response.

Wang, Dong-Rui, Wu, Xian-Lin, Sun, Ying-Li · 2022 · Signal transduction and targeted therapy · DOI

Full title: Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response.

Authors: Wang, Dong-Rui, Wu, Xian-Lin, Sun, Ying-Li

Year: 2022

Venue: Signal transduction and targeted therapy

DOI: https://doi.org/10.1038/s41392-022-01136-2

Paper CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.

Yang, Yuanzheng, Zhou, Yifan, Wang, Jian, Zhou, You, Watowich, Stephanie S, Kleinerman, Eugenie S · 2024 · Cancers · DOI

Full title: CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.

Authors: Yang, Yuanzheng, Zhou, Yifan, Wang, Jian, Zhou, You, Watowich, Stephanie S, Kleinerman, Eugenie S

Year: 2024

Venue: Cancers

DOI: https://doi.org/10.3390/cancers16193251

Paper Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives.

Shen, Ke-Yu, Zhu, Ying, Xie, Sun-Zhe, Qin, Lun-Xiu · 2024 · Journal of hematology & oncology · DOI

Full title: Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives.

Authors: Shen, Ke-Yu, Zhu, Ying, Xie, Sun-Zhe, Qin, Lun-Xiu

Year: 2024

Venue: Journal of hematology & oncology

DOI: https://doi.org/10.1186/s13045-024-01549-2

Paper Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni · 2021 · International Journal of Molecular Sciences · DOI

Full title: Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Authors: Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22126309

Paper Successful Response to Nivolumab Plus Ipilimumab Therapy in a Hemodialysis Patient With Metastatic Renal Cell Carcinoma.

Masuda, Hiroshi, Mikami, Kosuke, Otsuka, Kotaro, Hou, Kyokusin, Suyama, Takahito, Araki, Kazuhiro, Kojima, Satoko, Naya, Yukio · 2021 · Cancer diagnosis & prognosis · DOI

Full title: Successful Response to Nivolumab Plus Ipilimumab Therapy in a Hemodialysis Patient With Metastatic Renal Cell Carcinoma.

Authors: Masuda, Hiroshi, Mikami, Kosuke, Otsuka, Kotaro, Hou, Kyokusin, Suyama, Takahito, Araki, Kazuhiro, Kojima, Satoko, Naya, Yukio

Year: 2021

Venue: Cancer diagnosis & prognosis

DOI: https://doi.org/10.21873/cdp.10028

Paper Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells.

Motoshima, Takanobu, Komohara, Yoshihiro, Horlad, Hasita, Takeuchi, Ario, Maeda, Yoshihiro, Tanoue, Kenichiro, Kawano, Yoshiaki, Harada, Mamoru, Takeya, Motohiro, Eto, Masatoshi · 2015 · Oncology reports · DOI

Full title: Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells.

Authors: Motoshima, Takanobu, Komohara, Yoshihiro, Horlad, Hasita, Takeuchi, Ario, Maeda, Yoshihiro, Tanoue, Kenichiro, Kawano, Yoshiaki, Harada, Mamoru, Takeya, Motohiro, Eto, Masatoshi

Year: 2015

Venue: Oncology reports

DOI: https://doi.org/10.3892/or.2015.3893

Paper The Continuum of Thyroid Disorders Related to Immune Checkpoint Inhibitors: Still Many Pending Queries.

Deligiorgi, Maria V, Sagredou, Sofia, Vakkas, Lampros, Trafalis, Dimitrios T · 2021 · Cancers · DOI

Full title: The Continuum of Thyroid Disorders Related to Immune Checkpoint Inhibitors: Still Many Pending Queries.

Authors: Deligiorgi, Maria V, Sagredou, Sofia, Vakkas, Lampros, Trafalis, Dimitrios T

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13215277

Paper Efficacy and safety of PD-1/PD-L1 inhibitors in the treatment of recurrent and refractory ovarian cancer: A systematic review and a meta-analysis.

Zeng, Siyuan, Liu, Daju, Yu, Yongai, Zou, Lei, Jin, Xianyu, Liu, Bing, Liu, Lifeng · 2023 · Frontiers in pharmacology · DOI

Full title: Efficacy and safety of PD-1/PD-L1 inhibitors in the treatment of recurrent and refractory ovarian cancer: A systematic review and a meta-analysis.

Authors: Zeng, Siyuan, Liu, Daju, Yu, Yongai, Zou, Lei, Jin, Xianyu, Liu, Bing, Liu, Lifeng

Year: 2023

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2023.1111061

Paper Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Sundström, E., Huang, Xueting, Wiemer, Andrew J. · 2025 · Cancer Immunology Immunotherapy · DOI

Full title: Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Authors: Sundström, E., Huang, Xueting, Wiemer, Andrew J.

Year: 2025

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-025-04128-7

Paper Neoadjuvant PD-1/PD-L1 combined with CTLA-4 inhibitors for solid malignancies: a systematic review and meta-analysis.

Huang, Shuang, Zheng, Gang, Yang, Kai · 2023 · World journal of surgical oncology · DOI

Full title: Neoadjuvant PD-1/PD-L1 combined with CTLA-4 inhibitors for solid malignancies: a systematic review and meta-analysis.

Authors: Huang, Shuang, Zheng, Gang, Yang, Kai

Year: 2023

Venue: World journal of surgical oncology

DOI: https://doi.org/10.1186/s12957-023-03212-5

Paper How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Martini, Giulia, Ciardiello, Davide, Paragliola, Fernando, Nacca, Valeria, Santaniello, W., Urraro, Fabrizio, Stanzione, Maria, Niosi, Marco, Dallio, Marcello, Federico, Alessandro, Selvaggi, Francesco, Corte, Carminia Maria Della, Napolitano, Stefania, Ciardiello, Fortunato, Martinelli, Erika · 2021 · Cancers · DOI

Full title: How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Authors: Martini, Giulia, Ciardiello, Davide, Paragliola, Fernando, Nacca, Valeria, Santaniello, W., Urraro, Fabrizio, Stanzione, Maria, Niosi, Marco, Dallio, Marcello, Federico, Alessandro, Selvaggi, Francesco, Corte, Carminia Maria Della, Napolitano, Stefania, Ciardiello, Fortunato, Martinelli, Erika

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13184719

Paper Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina · 2021 · European journal of nuclear medicine and molecular imaging · DOI

Full title: Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

Authors: Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina

Year: 2021

Venue: European journal of nuclear medicine and molecular imaging

DOI: https://doi.org/10.1007/s00259-020-05054-9

Paper ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.

Pohl, Julia, Mincu, Raluca-Ileana, Mrotzek, Simone Maria, Hinrichs, Lena, Michel, Lars, Livingstone, Elisabeth, Zimmer, Lisa, Wakili, Reza, Schadendorf, Dirk, Rassaf, Tienush, Totzeck, Matthias · 2020 · Journal of clinical medicine · DOI

Full title: ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.

Authors: Pohl, Julia, Mincu, Raluca-Ileana, Mrotzek, Simone Maria, Hinrichs, Lena, Michel, Lars, Livingstone, Elisabeth, Zimmer, Lisa, Wakili, Reza, Schadendorf, Dirk, Rassaf, Tienush, Totzeck, Matthias

Year: 2020

Venue: Journal of clinical medicine

DOI: https://doi.org/10.3390/jcm9072060

Paper Efficacy and safety of immune checkpoint inhibitors combined with chemotherapy in patients with extensive-stage small cell lung cancer: a systematic review and meta-analysis of randomized controlled trials.

Chen, Chunlan, Tian, Peng, Zhong, Jiangshan, Fan, Xianming · 2023 · Frontiers in oncology · DOI

Full title: Efficacy and safety of immune checkpoint inhibitors combined with chemotherapy in patients with extensive-stage small cell lung cancer: a systematic review and meta-analysis of randomized controlled trials.

Authors: Chen, Chunlan, Tian, Peng, Zhong, Jiangshan, Fan, Xianming

Year: 2023

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2023.1151769

Paper Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Eijs, Mick J M van, Verheijden, Rik J., Wees, Stefanie A. van der, Nierkens, Stefan, Lindert, Anne S. R. van, Suijkerbuijk, Karijn P.M., Wijk, Femke van, Meyaard, Linde, Kuball, Jürgen, Oldenburg, Bas, Leusen, Jeanette H.W. · 2023 · Cancer Immunology Immunotherapy · DOI

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Authors: Eijs, Mick J M van, Verheijden, Rik J., Wees, Stefanie A. van der, Nierkens, Stefan, Lindert, Anne S. R. van, Suijkerbuijk, Karijn P.M., Wijk, Femke van, Meyaard, Linde, Kuball, Jürgen, Oldenburg, Bas, Leusen, Jeanette H.W.

Year: 2023

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-023-03541-0

Paper Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade.

Buchbinder, Elizabeth, Hodi, F Stephen · 2015 · The Journal of clinical investigation · DOI

Full title: Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade.

Authors: Buchbinder, Elizabeth, Hodi, F Stephen

Year: 2015

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI80012

Paper Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion

C. Bruss, K. Kellner, V. Albert, James A. Hutchinson, S. Seitz, O. Ortmann, G. Brockhoff, A. Wege · 2023 · Cancers · DOI

Full title: Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion

Authors: C. Bruss, K. Kellner, V. Albert, James A. Hutchinson, S. Seitz, O. Ortmann, G. Brockhoff, A. Wege

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15092615

Paper TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

Liu, Heng-Jia, Lizotte, Patrick H, Du, Heng, Speranza, Maria C, Lam, Hilaire C, Vaughan, Spencer, Alesi, Nicola, Wong, Kwok-Kin, Freeman, Gordon J, Sharpe, Arlene H, Henske, Elizabeth P · 2018 · JCI insight · DOI

Full title: TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

Authors: Liu, Heng-Jia, Lizotte, Patrick H, Du, Heng, Speranza, Maria C, Lam, Hilaire C, Vaughan, Spencer, Alesi, Nicola, Wong, Kwok-Kin, Freeman, Gordon J, Sharpe, Arlene H, Henske, Elizabeth P

Year: 2018

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.98674

Paper Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.

Hu, Guangqiang, Li, Zeng, Chen, Yongji, Liao, Hong, Zhou, Shukui · 2025 · Frontiers in immunology · DOI

Full title: Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.

Authors: Hu, Guangqiang, Li, Zeng, Chen, Yongji, Liao, Hong, Zhou, Shukui

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1664587

Paper The role of immune checkpoint inhibitors in prostate cancer.

Surdacki, Gabriel, Szudy-Szczyrek, Aneta, Gorący, Aneta, Chyl-Surdacka, Katarzyna, Hus, Marek · 2019 · Annals of agricultural and environmental medicine : AAEM · DOI

Full title: The role of immune checkpoint inhibitors in prostate cancer.

Authors: Surdacki, Gabriel, Szudy-Szczyrek, Aneta, Gorący, Aneta, Chyl-Surdacka, Katarzyna, Hus, Marek

Year: 2019

Venue: Annals of agricultural and environmental medicine : AAEM

DOI: https://doi.org/10.26444/aaem/96331

Paper CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade.

Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal · 2021 · Cancers · DOI

Full title: CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade.

Authors: Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13081935

Paper Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways

Feng Wang, Ayse Ece Cali Daylan, L. Deng, Jihua Yang, Janaki Sharma, C. Su, Shenduo Li, X. Zang, B. Halmos, A. Borczuk, Haiying Cheng · 2023 · Cancers · DOI

Full title: Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways

Authors: Feng Wang, Ayse Ece Cali Daylan, L. Deng, Jihua Yang, Janaki Sharma, C. Su, Shenduo Li, X. Zang, B. Halmos, A. Borczuk, Haiying Cheng

Year: 2023

Venue: Cancers

DOI: https://doi.org/10.3390/cancers15133372

Paper DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Vanpouille‐Box, Claire, Alard, Amandine, Aryankalayil, Molykutty J., Sarfraz, Yasmeen, Diamond, Julie M., Schneider, Robert J., Inghirami, Giorgio, Coleman, C. Norman, Formenti, Silvia C., Demaria, Sandra · 2017 · Nature Communications · DOI

Full title: DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Authors: Vanpouille‐Box, Claire, Alard, Amandine, Aryankalayil, Molykutty J., Sarfraz, Yasmeen, Diamond, Julie M., Schneider, Robert J., Inghirami, Giorgio, Coleman, C. Norman, Formenti, Silvia C., Demaria, Sandra

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms15618

Paper The future of combination immunotherapy in oesophageal adenocarcinoma.

Davern, Maria, Donlon, Noel E · 2023 · Frontiers in immunology · DOI

Full title: The future of combination immunotherapy in oesophageal adenocarcinoma.

Authors: Davern, Maria, Donlon, Noel E

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1217132

Paper Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model

Suarez, Eloah Rabello, Chang, De-Kuan, Sun, Jiusong, Sui, Jianhua, Freeman, Gordon J., Signoretti, Sabina, Zhu, Quan, Marasco, Wayne A. · 2016 · Oncotarget · DOI

Full title: Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model

Authors: Suarez, Eloah Rabello, Chang, De-Kuan, Sun, Jiusong, Sui, Jianhua, Freeman, Gordon J., Signoretti, Sabina, Zhu, Quan, Marasco, Wayne A.

Year: 2016

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.9114

Paper A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H. · 2020 · Current Oncology · DOI

Full title: A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Authors: Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H.

Year: 2020

Venue: Current Oncology

DOI: https://doi.org/10.3747/co.27.5223

Paper Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model.

Yoshimoto, Yuya, Suzuki, Yoshiyuki, Mimura, Kousaku, Ando, Ken, Oike, Takahiro, Sato, Hiro, Okonogi, Noriyuki, Maruyama, Takanori, Izawa, Shinichiro, Noda, Shin-ei, Fujii, Hideki, Kono, Koji, Nakano, Takashi · 2014 · PloS one · DOI

Full title: Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model.

Authors: Yoshimoto, Yuya, Suzuki, Yoshiyuki, Mimura, Kousaku, Ando, Ken, Oike, Takahiro, Sato, Hiro, Okonogi, Noriyuki, Maruyama, Takanori, Izawa, Shinichiro, Noda, Shin-ei, Fujii, Hideki, Kono, Koji, Nakano, Takashi

Year: 2014

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0092572

Paper Clinical observation of immune checkpoint inhibitors in the treatment of advanced pancreatic cancer: a real-world study in Chinese cohort.

Sun, Danyang, Ma, Junxun, Wang, Jinliang, Zhang, Fan, Wang, Lijie, Zhang, Sujie, Chen, Guangying, Li, Xiaoyan, Du, Wushuang, Cui, Pengfei, Hu, Yi · 2018 · Therapeutics and clinical risk management · DOI

Full title: Clinical observation of immune checkpoint inhibitors in the treatment of advanced pancreatic cancer: a real-world study in Chinese cohort.

Authors: Sun, Danyang, Ma, Junxun, Wang, Jinliang, Zhang, Fan, Wang, Lijie, Zhang, Sujie, Chen, Guangying, Li, Xiaoyan, Du, Wushuang, Cui, Pengfei, Hu, Yi

Year: 2018

Venue: Therapeutics and clinical risk management

DOI: https://doi.org/10.2147/TCRM.S173041

Paper Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics.

Zhang, Ying, Garofano, Francesca, Wu, Xiaolong, Schmid, Matthias, Krawitz, Peter, Essler, Markus, Schmidt-Wolf, Ingo G H · 2020 · Investigational new drugs · DOI

Full title: Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics.

Authors: Zhang, Ying, Garofano, Francesca, Wu, Xiaolong, Schmid, Matthias, Krawitz, Peter, Essler, Markus, Schmidt-Wolf, Ingo G H

Year: 2020

Venue: Investigational new drugs

DOI: https://doi.org/10.1007/s10637-020-00952-z

Paper Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund · 2021 · Cancers · DOI

Full title: Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Authors: Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13061430

Thesis Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Ascierto, PA; Atkins, M; Bifulco, C et al. · 2021 · Theses · DOI

Full title: Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Authors: Ascierto, PA; Atkins, M; Bifulco, C; Botti, G; Cochran, A; Davies, M; Demaria, S; Dummer, R; Ferrone, S; Formenti, S; Gajewski, TF; Garbe, C; Khleif, S; Kiessling, R; Lo, R; Lorigan, P; Arthur, GM; Masucci, G; Melero, I; Mihm, M; Palmieri, G; Parmiani, G; Puzanov, I; Romero, P; Schilling, B; Seliger, B; Stroncek, D; Taube, J; Tomei, S; Zarour, HM; Testori, A; Wang, E; Galon, J; Ciliberto, G; Mozzillo, N; Marincola, FM; Thurin, M

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/262597

Thesis A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors

van Not, Olivier J; Wind, Thijs T; Ismail, Rawa K et al. · 2023 · Theses · DOI

Full title: A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors

Authors: van Not, Olivier J; Wind, Thijs T; Ismail, Rawa K; Bhattacharya, Arkajyoti; Jalving, Mathilde; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Boers-Sonderen, Marye J; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; Haanen, John B; Kapiteijn, Ellen; Bloem, Manja; Piersma, Djura; van Rijn, Rozemarijn S; Stevense-den Boer, Marion; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Blokx, Willeke A M; Suijkerbuijk, Karijn P M; Fehrmann, Rudolf S N; Hospers, Geke A P

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/449336

Thesis Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma

Verheijden, Rik J.; Burgers, Femke H.; Janssen, Josephine C. et al. · 2024 · Theses · DOI

Full title: Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma

Authors: Verheijden, Rik J.; Burgers, Femke H.; Janssen, Josephine C.; Putker, Anouk E.; Veenstra, Sophie P.G.R.; Hospers, Geke A.P.; Aarts, Maureen J.B.; Hehenkamp, Karel W.; Doornebosch, Veerle L.E.; Verhaert, Marthe; van den Berkmortel, Franchette W.P.J.; Chatzidionysiou, Katerina; Llobell, Arturo; Barros, Milton; Maria, Alexandre T.J.; Takeji, Akari; García Morillo, José Salvador; Lidar, Merav; van Eijs, Mick J.M.; Blank, Christian U.; Aspeslagh, Sandrine; Piersma, Djura; Kapiteijn, Ellen; Labots, Mariette; Boers-Sonderen, Marye J.; van der Veldt, Astrid A.M.; Haanen, John B.A.G.; May, Anne M.; Suijkerbuijk, Karijn P.M.

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/453162

Thesis Economic evaluation of single versus combination immuno-oncology therapies: Application of a novel modelling approach in metastatic melanoma

Gibson, EJ; Begum, N; Koblbauer, I et al. · 2021 · Theses · DOI

Full title: Economic evaluation of single versus combination immuno-oncology therapies: Application of a novel modelling approach in metastatic melanoma

Authors: Gibson, EJ; Begum, N; Koblbauer, I; Dranitsaris, G; Liew, D; McEwan, P; Yuan, Y; Juarez-Garcia, A; Tyas, D; Pritchard, C

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/271942

Thesis Spotlight on landmark oncology trials: the latest evidence and novel trial designs

Earl, Helena; Molica, Stefano; Rutkowski, Piotr · 2017 · Theses · DOI

Full title: Spotlight on landmark oncology trials: the latest evidence and novel trial designs

Authors: Earl, Helena; Molica, Stefano; Rutkowski, Piotr

Year: 2017

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/264598

Thesis Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies

Van Not, Olivier J; van den Eertwegh, Alfons J M; Haanen, John B et al. · 2023 · Theses · DOI

Full title: Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies

Authors: Van Not, Olivier J; van den Eertwegh, Alfons J M; Haanen, John B; van Rijn, Rozemarijn S; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; van Eijs, Mick J M; de Groot, Jan-Willem B; Hospers, Geke A P; Kapiteijn, Ellen; de Meza, Melissa; Piersma, Djura; Stevense-den Boer, Marion; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Suijkerbuijk, Karijn P M; Blokx, Willeke A M

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/448987

Thesis The Epstein-Barr Virus Hacks Immune Checkpoints: Evidence and Consequences for Lymphoproliferative Disorders and Cancers

Biggi, Alison Felipe Bordini [UNESP]; de Oliveira, Deilson Elgui [UNESP] · 2022 · Theses · DOI

Full title: The Epstein-Barr Virus Hacks Immune Checkpoints: Evidence and Consequences for Lymphoproliferative Disorders and Cancers

Authors: Biggi, Alison Felipe Bordini [UNESP]; de Oliveira, Deilson Elgui [UNESP]

Year: 2022

Venue: Theses

DOI: http://dx.doi.org/10.3390/biom12030397

Thesis Role Of Il-27 And Tcr Stimulation In Inhibitory Receptor Expression

Delong, Jonathan Howard · 2023 · University of Pennsylvania · DOI

Full title: Role Of Il-27 And Tcr Stimulation In Inhibitory Receptor Expression

Authors: Delong, Jonathan Howard

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/30093

Thesis Immunotherapy for Renal Cancer: Sequencing and Combinations

Stewart, GD; De Santis, M; Escudier, B et al. · 2017 · Theses · DOI

Full title: Immunotherapy for Renal Cancer: Sequencing and Combinations

Authors: Stewart, GD; De Santis, M; Escudier, B; Powles, T; Sonpavde, G

Year: 2017

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/265376

Thesis The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive et al. · 2024 · Theses · DOI

Full title: The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Authors: Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive; Fox, Bernard; Ibrahim, Ramy; Sharma, Padmanee; Allison, James P.; Maio, Michele

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/454126

Thesis Podnl1 methylation serves as a prognostic biomarker and associates with immune cell infiltration and immune checkpoint blockade response in lower-grade glioma

Noor, H; https://orcid.org/0000-0001-8887-8122; Zaman, A et al. · 2021 · Theses · DOI

Full title: Podnl1 methylation serves as a prognostic biomarker and associates with immune cell infiltration and immune checkpoint blockade response in lower-grade glioma

Authors: Noor, H ; https://orcid.org/0000-0001-8887-8122; Zaman, A ; https://orcid.org/0000-0002-2492-5281; Teo, C; Sughrue, ME

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/1959.4/104080

Thesis Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Sandin, Linda · 2013 · Theses · DOI

Full title: Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Authors: Sandin, Linda

Year: 2013

Venue: Theses

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210080

Thesis CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

Fietz, Simon; Zarbl, Romina; Niebel, Dennis et al. · 2020 · Theses · DOI

Full title: CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

Authors: Fietz, Simon;Zarbl, Romina;Niebel, Dennis;Posch, Christian;Brossart, Peter;Gielen, Gerrit H.;Strieth, Sebastian;Pietsch, Torsten;Kristiansen, Glen;Bootz, Friedrich;Landsberg, Jennifer;Dietrich, Dimo

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1624233

Thesis Two distinct clinical patterns of checkpoint inhibitor-induced thyroid dysfunction

Olsson-Brown, Anna; Lord, Rosemary; Sacco, Joseph et al. · 2020 · Theses · DOI

Full title: Two distinct clinical patterns of checkpoint inhibitor-induced thyroid dysfunction

Authors: Olsson-Brown, Anna; Lord, Rosemary; Sacco, Joseph; Wagg, Jonathan; Coles, Mark; Pirmohamed, Munir

Year: 2020

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3100413/1/Two%20distinct%20clinical%20patterns%20of%20checkpoint%20inhibitor-induced%20thyroid%20dysfunction.pdf

Thesis Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma

Lelliott, EJ; McArthur, GA; Oliaro, J et al. · 2021 · Theses · DOI

Full title: Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma

Authors: Lelliott, EJ; McArthur, GA; Oliaro, J; Sheppard, KE

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/278309

Thesis Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders

Brown, LJ; Weppler, A; Bhave, P et al. · 2021 · Theses · DOI

Full title: Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders

Authors: Brown, LJ; Weppler, A; Bhave, P; Allayous, C; Patrinely, JR; Ott, P; Sandhu, S; Haydon, A; Lebbe, C; Johnson, DB; Long, GV; Menzies, AA; Carlino, MS

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/280628

Thesis Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Nguyen, Kim Bich; Spranger, Stefani · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Authors: Nguyen, Kim Bich; Spranger, Stefani

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/135977

Thesis Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma

Schuiveling, M; Tonk, E H J; Verheijden, R J et al. · 2021 · Theses · DOI

Full title: Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma

Authors: Schuiveling, M; Tonk, E H J; Verheijden, R J; Suijkerbuijk, K P M

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/440555

Thesis Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Regev, Aviv · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Authors: Regev, Aviv

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/125051

Thesis Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity

Hammond, Sean; Olsson-Brown, Anna; Grice, Sophie et al. · 2022 · University of Liverpool · DOI

Full title: Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity

Authors: Hammond, Sean; Olsson-Brown, Anna; Grice, Sophie; Gibson, Andrew; Gardner, Joshua; Castrejon-Flores, Jose Luis; Jolly, Carol; Fisher, Benjamin Alexis; Steven, Neil; Betts, Catherine; Pirmohamed, Munir; Meng, Xiaoli; Naisbitt, Dean John

Year: 2022

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3150513/1/Checkpoint%20Inhibition%20Reduces%20the%20Threshold%20for%20Drug-Specific%20T-Cell%20Priming%20and%20Increases%20the%20Incidence%20of%20Sulfasalazine%20Hy.pdf

Thesis Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials

Verheijden, Rik J; de Groot, Jolien S; Fabriek, Babs O et al. · 2024 · Theses · DOI

Full title: Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials

Authors: Verheijden, Rik J; de Groot, Jolien S; Fabriek, Babs O; Hew, Miki N; May, Anne M; Suijkerbuijk, Karijn P M

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/458069

Thesis Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Guillén, Noelia Carolina Talavera [UNESP] · 2023 · Theses · DOI

Full title: Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Authors: Guillén, Noelia Carolina Talavera [UNESP]

Year: 2023

Venue: Theses

DOI: http://hdl.handle.net/11449/239302

Thesis Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Duchnowska, R; Peksa, R; Radecka, B et al. · 2021 · Theses · DOI

Full title: Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Authors: Duchnowska, R; Peksa, R; Radecka, B; Mandat, T; Trojanowski, T; Jarosz, B; Czartoryska-Arłukowicz, B; Olszewski, WP; Och, W; Kalinka-Warzocha, E; Kozłowski, W; Kowalczyk, A; Loi, S; Biernat, W; Jassem, J

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/260579

Thesis Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Oliver, AJ; Keam, SP; von Scheidt, B et al. · 2020 · Theses · DOI

Full title: Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Authors: Oliver, AJ; Keam, SP; von Scheidt, B; Zanker, DJ; Harrison, AJ; Tantalo, DGM; Darcy, PK; Kershaw, MH; Slaney, CY

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/247618

Thesis Emerging role of PTEN loss in evasion of the immune response to tumours

Vidotto, Thiago; Melo, Camila Morais; Castelli, Erick [UNESP] et al. · 2020 · Theses · DOI

Full title: Emerging role of PTEN loss in evasion of the immune response to tumours

Authors: Vidotto, Thiago; Melo, Camila Morais; Castelli, Erick [UNESP]; Koti, Madhuri; Reis, Rodolfo Borges dos; Squire, Jeremy A.

Year: 2020

Venue: Theses

DOI: http://dx.doi.org/10.1038/s41416-020-0834-6

Thesis Mechanisms of response and resistance to anti-PD-1 immunotherapy

Edwards, Jarem · 2022 · Theses · DOI

Full title: Mechanisms of response and resistance to anti-PD-1 immunotherapy

Authors: Edwards, Jarem

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/2123/29470

Thesis Immune checkpoints as gatekeepers of CD8+ T cell differentiation

Carrera Haro, Maria Augusta · 2019 · Theses · DOI

Full title: Immune checkpoints as gatekeepers of CD8+ T cell differentiation

Authors: Carrera Haro, Maria Augusta

Year: 2019

Venue: Theses

DOI: http://jhir.library.jhu.edu/handle/1774.2/61568

Thesis Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients

Biewenga, Maaike; van der Kooij, Monique K; Wouters, Michel W J M et al. · 2021 · Theses · DOI

Full title: Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients

Authors: Biewenga, Maaike; van der Kooij, Monique K; Wouters, Michel W J M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; de Groot, Jan Willem B; Boers-Sonderen, Marye J; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Haanen, John B A G; van der Eertwegh, Alfons J M; van Hoek, Bart; Kapiteijn, Ellen

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442328

Thesis Effektivität von neuen systemtherapeutischen Optionen bei Patienten mit metastasiertem Nierenzellkarzinom

Sandin, Per Niklas · 2025 · Theses · DOI

Full title: Effektivität von neuen systemtherapeutischen Optionen bei Patienten mit metastasiertem Nierenzellkarzinom

Authors: Sandin, Per Niklas

Year: 2025

Venue: Theses

DOI: https://refubium.fu-berlin.de/handle/fub188/47981

Thesis Withdrawal of β-catenin in an Inducible Genetically Engineered Mouse Model Restores T Cell Infiltration but Not Checkpoint Blockade Efficacy

Cabanov, Alexandra · 2024 · University of Chicago - Knowledge@UChicago · DOI

Full title: Withdrawal of β-catenin in an Inducible Genetically Engineered Mouse Model Restores T Cell Infiltration but Not Checkpoint Blockade Efficacy

Authors: Cabanov, Alexandra

Year: 2024

Venue: University of Chicago - Knowledge@UChicago

DOI: https://knowledge.uchicago.edu/record/12428/files/Cabanov_uchicago_0330D_17485.pdf

Thesis Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis et al. · 2017 · Theses · DOI

Full title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Authors: Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis; Szeto, Gregory; Tzeng, Alice; Zhu, Eric Franklin; Engreitz, Jesse Michael; Williams, Robert T.; Rakhra, Kavya; Zhang, Michael H; Rothschilds, Adrienne Marie; Kumari, Sudha; Kelly, Ryan Lewis; Kwan, Byron Hua; Abraham, Wuhbet; Hu, Kevin; Mehta, Naveen; Kauke, Monique Jacqueline; Suh, Heikyung; Lauffenburger, Douglas A; Wittrup, Karl Dane; Irvine, Darrell J

Year: 2017

Venue: Theses

DOI: http://hdl.handle.net/1721.1/109826

Thesis Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study

van Not, Olivier J; de Meza, Melissa M; van den Eertwegh, Alfons J M et al. · 2022 · Theses · DOI

Full title: Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study

Authors: van Not, Olivier J; de Meza, Melissa M; van den Eertwegh, Alfons J M; Haanen, John B; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; van Breeschoten, Jesper; de Groot, Jan-Willem B; Hospers, Geke A P; Ismail, Rawa K; Kapiteijn, Ellen; Piersma, Djura; van Rijn, Roos S; Stevense-den Boer, Marion A M; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Bonenkamp, Han J; Boers-Sonderen, Marye J; Blokx, Willeke A M; Wouters, Michel W J M; Suijkerbuijk, Karijn P M

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/446113

Thesis The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Kuchroo, Juhi · 2020 · Theses · DOI

Full title: The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Authors: Kuchroo, Juhi

Year: 2020

Venue: Theses

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365910

Thesis Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Iyer, Nivedha Srikanth · 2024 · Theses · DOI

Full title: Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Authors: Iyer, Nivedha Srikanth

Year: 2024

Venue: Theses

DOI: https://escholarship.org/uc/item/5m579278

Thesis **Institution:** University of Melbourne **Date:** 2021-05-11T01:43:51Z

Dorff, T; Rettig, M; Machiels, J-P et al. · 2021 · Theses · DOI

Full title: **Institution:** University of Melbourne **Date:** 2021-05-11T01:43:51Z

Authors: Dorff, T; Rettig, M; Machiels, J-P; Lolkema, M; Autio, K; Greil, R; Rottey, S; Adra, N; Salvati, M; Poon, S; Tan, D; Jurida, G; Kouros-Mehr, H; Fizazi, K; Tran, B; Horvath, L

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/273969

Thesis A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Conduit, C; Davis, ID; Goh, JC et al. · 2024 · Theses · DOI

Full title: A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Authors: Conduit, C; Davis, ID; Goh, JC; Kichenadasse, G; Gurney, H; Harris, CA; Pook, D; Krieger, L; Parnis, F; Underhill, C; Adams, D; Roncolato, F; Joshua, A; Ferguson, T; Prithviraj, P; Morris, M; Harrison, M; Begbie, S; Hovey, E; George, M; Liow, EC; Link, EK; McJannett, M; Gedye, C

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/339980

Thesis Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Klein, O; Kee, D; Gao, B et al. · 2022 · Theses · DOI

Full title: Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Authors: Klein, O; Kee, D; Gao, B; Markman, B; Da Gama Duarte, J; Quigley, L; Jackett, L; Linklater, R; Strickland, A; Scott, C; Mileshkin, L; Palmer, J; Carlino, M; Behren, A; Cebon, J

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/296391

Thesis Tissue-specific tumor microenvironments influence responses to immunotherapies

Oliver, AJ; Davey, AS; Keam, SP et al. · 2020 · Theses · DOI

Full title: Tissue-specific tumor microenvironments influence responses to immunotherapies

Authors: Oliver, AJ; Davey, AS; Keam, SP; Mardiana, S; Chan, JD; von Scheidt, B; Beavis, PA; House, IG; Van Audernaerde, JRM; Darcy, PK; Kershaw, MH; Slaney, CY

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/247124

Thesis An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Bottai, G; Raschioni, C; Losurdo, A et al. · 2020 · Theses · DOI

Full title: An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Authors: Bottai, G; Raschioni, C; Losurdo, A; Di Tommaso, L; Tinterri, C; Torrisi, R; Reis-Filho, JS; Roncalli, M; Sotiriou, C; Santoro, A; Mantovani, A; Loi, S; Santarpia, L

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/257795

Thesis Mechanisms Of Lung Cancer Hyper-Progression Promoted By Pd-1 Immune Checkpoint Blockade

Martinez-Usatorre, A.; Kadioglu, E.; Cianciaruso, C. et al. · 2021 · Theses · DOI

Full title: Mechanisms Of Lung Cancer Hyper-Progression Promoted By Pd-1 Immune Checkpoint Blockade

Authors: Martinez-Usatorre, A.; Kadioglu, E.; Cianciaruso, C.; Torchia, B.; Faget, J.; Meylan, E.; Schmittnaegel, M.; Keklikoglou, I.; De Palma, M.

Year: 2021

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/176286

Thesis Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Wang, M; Zadeh, S; Pizzolla, A et al. · 2022 · University of Melbourne · DOI

Full title: Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Authors: Wang, M; Zadeh, S; Pizzolla, A; Thia, K; Gyorki, DE; McArthur, GA; Scolyer, RA; Long, G; Wilmott, JS; Andrews, MC; Au-Yeung, G; Weppler, A; Sandhu, S; Trapani, JA; Davis, MJ; Neeson, PJ

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/307216

Thesis Biomarkers in immuno-oncology : from melanoma to other cancer types, from tissue to liquid biopsy, from late stage to early stage disease

Meireson, Annabel · 2022 · Theses · DOI

Full title: Biomarkers in immuno-oncology : from melanoma to other cancer types, from tissue to liquid biopsy, from late stage to early stage disease

Authors: Meireson, Annabel

Year: 2022

Venue: Theses

DOI: https://biblio.ugent.be/publication/8742933

Thesis First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update

Reck, M; Ciuleanu, TE; Cobo, M et al. · 2022 · Theses · DOI

Full title: First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update

Authors: Reck, M; Ciuleanu, TE; Cobo, M; Schenker, M; Zurawski, B; Menezes, J; Richardet, E; Bennouna, J; Felip, E; Juan-Vidal, O; Alexandru, A; Sakai, H; Lingua, A; Reyes, F; Souquet, PJ; De Marchi, P; Martin, C; Pérol, M; Scherpereel, A; Lu, S; Paz-Ares, L; Carbone, DP; Memaj, A; Marimuthu, S; Zhang, X; Tran, P; John, T

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/308764

Thesis Rare Immune-Related Adverse Events (irAEs): Approach to Diagnosis and Management

Javaid, A; Bennett, C; Rao, A et al. · 2025 · Theses · DOI

Full title: Rare Immune-Related Adverse Events (irAEs): Approach to Diagnosis and Management

Authors: Javaid, A; Bennett, C; Rao, A; Spain, L

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/358266

Thesis Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma

Leek, Lindsay V M; Notohardjo, Jessica C L; de Joode, Karlijn et al. · 2024 · Theses · DOI

Full title: Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma

Authors: Leek, Lindsay V M; Notohardjo, Jessica C L; de Joode, Karlijn; Velker, Eline L; Haanen, John B A G; Suijkerbuijk, Karijn P M; Aarts, Maureen J B; de Groot, Jan Willem B; Kapiteijn, Ellen; van den Berkmortel, Franchette W P J; Westgeest, Hans M; de Gruijl, Tanja D; Retel, Valesca P; Cuppen, Edwin; van der Veldt, Astrid A M; Labots, Mariette; Voest, Emile E; van de Haar, Joris; van den Eertwegh, Alfons J M

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/452909

Thesis Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

Laia Gorchs (18664483) · 2022 · Karolinska Institutet · DOI

Full title: Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

Authors: Laia Gorchs (18664483)

Year: 2022

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26906092

Thesis LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma

Klümper, N; Ralser, DJ; Bawden, EG et al. · 2021 · Theses · DOI

Full title: LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma

Authors: Klümper, N; Ralser, DJ; Bawden, EG; Landsberg, J; Zarbl, R; Kristiansen, G; Toma, M; Ritter, M; Hölzel, M; Ellinger, J; Dietrich, D

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277676

Thesis Survival in early phase immuno-oncology trials: Development and validation of a prognostic index

Day, D; Guo, C; Kanjanapan, Y et al. · 2021 · Theses · DOI

Full title: Survival in early phase immuno-oncology trials: Development and validation of a prognostic index

Authors: Day, D; Guo, C; Kanjanapan, Y; Tran, B; Spreafico, A; Joshua, AM; Wang, L; Abdul Razak, AR; Leighl, NB; Hansen, AR; Butler, MO; Siu, LL; Desai, J; Bedard, PL

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/271795

Thesis Exploring the Interplay of Oncolytic Measles Vaccines with the Cancer-Immunity Cycle

Pidelaserra Martí, Gemma · 2024 · Theses · DOI

Full title: Exploring the Interplay of Oncolytic Measles Vaccines with the Cancer-Immunity Cycle

Authors: Pidelaserra Martí, Gemma

Year: 2024

Venue: Theses

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34509/1/2023-10-19_PhD_Thesis_GemmaPidelaserraMarti.pdf

Thesis Sex-Based Differences in Treatment with Immune Checkpoint Inhibition and Targeted Therapy for Advanced Melanoma: A Nationwide Cohort Study

van der Kooij, Monique K; Dekkers, Olaf M; Aarts, Maureen J B et al. · 2021 · Theses · DOI

Full title: Sex-Based Differences in Treatment with Immune Checkpoint Inhibition and Targeted Therapy for Advanced Melanoma: A Nationwide Cohort Study

Authors: van der Kooij, Monique K; Dekkers, Olaf M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Boers-Sonderen, Marye J; de Groot, Jan Willem B; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Westgeest, Hans M; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wilgenhof, Sofie; Wouters, Michel W J M; Haanen, John B A G; van den Eertwegh, Alfonsus J M; Kapiteijn, Ellen

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/443821

Thesis Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Ferris, Robert L; Spanos, William C; Leidner, Rom et al. · 2021 · Theses · DOI

Full title: Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Authors: Ferris, Robert L; Spanos, William C; Leidner, Rom; Gonçalves, Anthony; Martens, Uwe M; Kyi, Chrisann; Sharfman, William; Chung, Christine H; Devriese, Lot A; Gauthier, Helene; Chiosea, Simon I; Vujanovic, Lazar; Taube, Janis M; Stein, Julie E; Li, Jun; Li, Bin; Chen, Tian; Barrows, Adam; Topalian, Suzanne L

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442886

Thesis Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M et al. · 2022 · Theses · DOI

Full title: Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

Authors: van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M; Haanen, John B A G; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; de Groot, Jan-Willem B; Hospers, Geke A P; Kamphuis, Anna M; Kapiteijn, Ellen; May, Anne M; de Meza, Melissa M; Piersma, Djura; van Rijn, Rozemarijn; Stevense-den Boer, Marion A; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Blokx, Willeke A M; Wouters, Michel J M; Suijkerbuijk, Karijn P M

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/447350

Thesis Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Wein, L; Luen, SJ; Savas, P et al. · 2020 · Theses · DOI

Full title: Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Authors: Wein, L; Luen, SJ; Savas, P; Salgado, R; Loi, S

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/255249

Thesis Single cell landscape of innate and adaptive immunity in metastatic melanoma treated with immunotherapy

Fu, Ruiwen · 2022 · Theses · DOI

Full title: Single cell landscape of innate and adaptive immunity in metastatic melanoma treated with immunotherapy

Authors: Fu, Ruiwen

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/144938

Thesis T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

Evans, Rebecca A · 2023 · University of Pennsylvania · DOI

Full title: T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

Authors: Evans, Rebecca A

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/28546

Thesis TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes

Trivedi, P; Jhala, G; De George, DJ et al. · 2024 · University of Melbourne · DOI

Full title: TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes

Authors: Trivedi, P; Jhala, G; De George, DJ; Chiu, C; Selck, C; Ge, T; Catterall, T; Elkerbout, L; Boon, L; Joller, N; Kay, TW; Thomas, HE; Krishnamurthy, B

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/353275

Thesis What is the ideal endpoint in early-stage immunotherapy neoadjuvant trials in lung cancer?

Cameron, Robert B; Hines, Jacobi B; Torri, Valter et al. · 2023 · Theses · DOI

Full title: What is the ideal endpoint in early-stage immunotherapy neoadjuvant trials in lung cancer?

Authors: Cameron, Robert B; Hines, Jacobi B; Torri, Valter; Porcu, Luca; Donington, Jessica; Bestvina, Christine M; Vokes, Everett; Dolezal, James M; Esposito, Alessandra; Garassino, Marina C

Year: 2023

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/357602

Thesis Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas

Sanghvi, Khwab · 2023 · Heidelberg University · DOI

Full title: Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas

Authors: Sanghvi, Khwab

Year: 2023

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/33640/1/Dissertation_Khwab%20Sanghvi_2023.pdf

Thesis FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma

Zhou, L; Barros E Silva, MJ; Hsiao, E et al. · 2025 · Theses · DOI

Full title: FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma

Authors: Zhou, L; Barros E Silva, MJ; Hsiao, E; Eroglu, Z; Sandhu, S; Samoylenko, I; Lo, SN; Carlino, MS; Au-Yeung, G; Gonzalez, M; Spillane, AJ; Pennington, TE; Shannon, KF; Kapoor, R; Burton, EM; Tawbi, HA; Amaria, RN; Blank, CU; Duprat, JP; Brito De Paula, R; Gyorki, DE; Saw, RPM; Ch'ng, S; Rawson, RV; Scolyer, RA; Pires Da Silva, I; Akkooi, ACJV; Long, GV; Menzies, AM

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/360308

Thesis 817 Activated osteoarthritis following immune checkpoint inhibitor treatment: an observational study

Reid, P; Liew, D; Akruwala, R et al. · 2022 · Theses · DOI

Full title: 817 Activated osteoarthritis following immune checkpoint inhibitor treatment: an observational study

Authors: Reid, P; Liew, D; Akruwala, R; Bass, A; Chan, K

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/307941

Thesis The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021 · Theses · DOI

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Authors: Coen, Oliver; Corrie, Pippa; Marshall, Helen; Plummer, Ruth; Ottensmeier, Christian; Hook, Jane; Bell, Sue; Sagoo, Gurdeep S; Meads, David; Bestall, Janine; Velikova, Galina; Gallagher, Ferdia A; Smith, Alexandra; Howard, Helen; Mason, Ellen; Katona, Eszter; Silva, Shobha; Collinson, Michelle; Rodwell, Simon; Danson, Sarah

Year: 2021

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/327626

Thesis Regulation of the Inflamed Tumor Phenotype in Melanoma Immunotherapy

Lo, Jennifer · 2017 · Theses · DOI

Full title: Regulation of the Inflamed Tumor Phenotype in Melanoma Immunotherapy

Authors: Lo, Jennifer

Year: 2017

Venue: Theses

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493467

Thesis 63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Reck, M; Regan, M; Carbone, DP et al. · 2024 · Theses · DOI

Full title: 63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Authors: Reck, M; Regan, M; Carbone, DP; Lu, S; John, T; Penrod, J; Li, J; Yuan, Y; Mahmood, J; Lee, A; Eccles, L; Ray, S; Paz-Ares, L

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/351905

Thesis Dual CD47 and PD-L1 blockade elicits anti-tumor immunity by intratumoral CD8+ T cells

Christo, SN; Mcdonald, KM; Burn, TN et al. · 2025 · Theses · DOI

Full title: Dual CD47 and PD-L1 blockade elicits anti-tumor immunity by intratumoral CD8+ T cells

Authors: Christo, SN; Mcdonald, KM; Burn, TN; Kurd, N; Stanfield, J; Kaneda, MM; Seelige, R; Dillon, CP; Fisher, TS; Baaten, B; Mackay, LK

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/359226

Thesis Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response

van der Kooij, Monique K; Wetzels, Marjolein J A L; Aarts, Maureen J B et al. · 2020 · Theses · DOI

Full title: Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response

Authors: van der Kooij, Monique K; Wetzels, Marjolein J A L; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; Dierselhuis, Miranda P; de Groot, Jan Willem B; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Haanen, John B A G; van den Eertwegh, Alfonsus J M; Bastiaannet, Esther; Kapiteijn, Ellen

Year: 2020

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/440167

Thesis The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A et al. · 2022 · Theses · DOI

Full title: The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Authors: Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A; Pattada, Nimisha B; Bhutkar, Arjun; Eng, George; Mercer, Kim L; Garcia, Ana P; Lin, Lin; Rideout, William M; Hwang, William L; Schenkel, Jason M; Jaeger, Alex M; Bronson, Roderick T; Westcott, Peter MK; Hether, Tyler D; Divakar, Prajan; Reeves, Jason W; Deshpande, Vikram; Delorey, Toni; Phillips, Devan; Yilmaz, Omer H; Regev, Aviv; Jacks, Tyler

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/146821

Thesis An Investigation into the Immunological Mechanisms of Immune Related Adverse Events Associated with Oncological Immune Checkpoint Inhibitors

Olsson-Brown, Anna · 2022 · Theses · DOI

Full title: An Investigation into the Immunological Mechanisms of Immune Related Adverse Events Associated with Oncological Immune Checkpoint Inhibitors

Authors: Olsson-Brown, Anna

Year: 2022

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3154960/1/200131723_Jul2021.pdf

Thesis Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin et al. · 2018 · Theses · DOI

Full title: Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Authors: Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin; Joshi, Kroopa; Rosenthal, Rachel; Ghorani, Ehsan; Solomon, Isabelle; Lesko, Marta H; Ruef, Nora; Roddie, Claire; Henry, Jake Y; Spain, Lavinia; Ben Aissa, Assma; Georgiou, Andrew; Wong, Yien Ning Sophia; Smith, Myles; Strauss, Dirk; Hayes, Andrew; Nicol, David; O'Brien, Tim; Mårtensson, Linda; Ljungars, Anne; Teige, Ingrid; Frendéus, Björn; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia; Pule, Martin; Marafioti, Teresa; Gore, Martin; Larkin, James; Turajlic, Samra; Swanton, Charles; Peggs, Karl S; Quezada, Sergio A

Year: 2018

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/277642

Thesis Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Zhang, J; Liang, W; Liang, H et al. · 2024 · Theses · DOI

Full title: Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Authors: Zhang, J; Liang, W; Liang, H; Wang, X; He, J

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/350365

Thesis Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022 · Theses · DOI

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Authors: Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien; Verheem, André; Cercel, Madalina; Van Hal, Susan; Boj, Sylvia F.; Borel Rinkes, Inne H.M.; Punt, Cornelis J.A.; Roodhart, Jeanine M.L.; Laoukili, Jamila; Koopman, Miriam; Spits, Hergen; Kranenburg, Onno

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer

Li, C; Ferro, A; Mhatre, SK et al. · 2022 · Theses · DOI

Full title: Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer

Authors: Li, C; Ferro, A; Mhatre, SK; Lu, D; Lawrance, M; Li, X; Li, S; Allen, S; Desai, J; Fakih, M; Cecchini, M; Pedersen, KS; Kim, TY; Reyes-Rivera, I; Segal, NH; Lenain, C

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/316894

Thesis 3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

Portell, Andrew; Larios, Dalia; Piel, Brandon P. et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: 3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

Authors: Portell, Andrew; Larios, Dalia; Piel, Brandon P.; Mathur, Natasha; Zhou, Chensheng; Coakley, Raven Vlahos; Bartels, Alan; Bowden, Michaela; Herbert, Zach; Gilhooley, Sean; Carter, Jacob; Cañadas, Israel; Thai, Tran C.; Kitajima, Shunsuke; Chiono, Valeria; Paweletz, Cloud P.; Jenkins, Russell W.; Aref, Amir Reza; Ivanova, Elena; Campisi, Marco; Hill, Sarah J; Barbie, David; Kamm, Roger Dale

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/118112

Thesis Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma

Wang, M; Qin, L; Thia, K et al. · 2025 · Theses · DOI

Full title: Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma

Authors: Wang, M; Qin, L; Thia, K; Nguyen, T; MacDonald, S; Belobrov, S; Kranz, S; Goode, D; Trapani, JA; Wiesenfeld, D; Neeson, PJ

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/358856

Thesis Priming systemic anti-tumor immunity via in situ immunomodulation of the tumor microenvironment

Milling, Lauren Elizabeth · 2022 · Theses · DOI

Full title: Priming systemic anti-tumor immunity via in situ immunomodulation of the tumor microenvironment

Authors: Milling, Lauren Elizabeth

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/139220

Thesis Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma

Wolchok, JD; Chiarion-Sileni, V; Gonzalez, R et al. · 2022 · Theses · DOI

Full title: Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma

Authors: Wolchok, JD; Chiarion-Sileni, V; Gonzalez, R; Grob, JJ; Rutkowski, P; Lao, CD; Cowey, CL; Schadendorf, D; Wagstaff, J; Dummer, R; Ferrucci, PF; Smylie, M; Butler, MO; Hill, A; Márquez-Rodas, I; Haanen, JBAG; Guidoboni, M; Maio, M; Schöffski, P; Carlino, MS; Lebbé, C; McArthur, G; Ascierto, PA; Daniels, GA; Long, GV; Bas, T; Ritchings, C; Larkin, J; Hodi, FS

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/301620

Thesis First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in advanced non-small cell lung cancer: a subanalysis of Asian patients in CheckMate 9LA

John, T; Sakai, H; Ikeda, S et al. · 2022 · Theses · DOI

Full title: First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in advanced non-small cell lung cancer: a subanalysis of Asian patients in CheckMate 9LA

Authors: John, T; Sakai, H; Ikeda, S; Cheng, Y; Kasahara, K; Sato, Y; Nakahara, Y; Takeda, M; Kaneda, H; Zhang, H; Maemondo, M; Minato, K; Hisada, T; Misumi, Y; Satouchi, M; Hotta, K; Li, A; Oukessou, A; Lu, S

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/308143

Thesis Efficacy of immune checkpoint inhibitors for in-transit melanoma

Tie, EN; Lai-Kwon, J; Rtshiladze, MA et al. · 2020 · Theses · DOI

Full title: Efficacy of immune checkpoint inhibitors for in-transit melanoma

Authors: Tie, EN; Lai-Kwon, J; Rtshiladze, MA; Na, L; Bozzi, J; Read, T; Atkinson, V; Au-Yeung, G; Long, GV; McArthur, GA; Sandhu, S; Saw, R; Walpole, E; Menzies, A; Smithers, M; Gyorki, DE

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/246341

Thesis Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Lammers, Marshall · 2025 · Theses · DOI

Full title: Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Authors: Lammers, Marshall

Year: 2025

Venue: Theses

DOI: https://escholarship.org/uc/item/62w1z16d

Thesis A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Arnaud-Coffin, P; Maillet, D; Gan, HK et al. · 2021 · Theses · DOI

Full title: A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Authors: Arnaud-Coffin, P; Maillet, D; Gan, HK; Stelmes, J-J; You, B; Dalle, S; Peron, J

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/285412

Thesis Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

Figueiredo, Carlos R; Kalirai, Helen; Sacco, Joseph J et al. · 2020 · Theses · DOI

Full title: Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

Authors: Figueiredo, Carlos R; Kalirai, Helen; Sacco, Joseph J; Azevedo, Ricardo A; Duckworth, Andrew; Slupsky, Joseph R; Coulson, Judy M; Coupland, Sarah E

Year: 2020

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3074857/1/Journal%20of%20Pathology_Figueiredo_et_al-2020.pdf

Thesis Longitudinale Veränderung der Immunzellzusammensetzung von Patient*innen mit kolorektalem Karzinom unter kombinatorischer Immuntherapie mit Avelumab

Martin, Markus Paul · 2025 · Theses · DOI

Full title: Longitudinale Veränderung der Immunzellzusammensetzung von Patient*innen mit kolorektalem Karzinom unter kombinatorischer Immuntherapie mit Avelumab

Authors: Martin, Markus Paul

Year: 2025

Venue: Theses

DOI: https://refubium.fu-berlin.de/handle/fub188/45863

Thesis Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S. et al. · 2024 · Theses · DOI

Full title: Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

Authors: van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S.; van Amsterdam, Wouter A.C.; van den Berkmortel, Franchette; Boers-Sonderen, Marye; de Groot, Jan Willem B.; Hospers, Geke A.P.; Kapiteijn, Ellen; Labots, Mariette; Piersma, Djura; Schrader, Anne M.R.; Vreugdenhil, Gerard; Westgeest, Hans; Veta, Mitko; Blokx, Willeke A.M.; van Diest, Paul J.; Suijkerbuijk, Karijn P.M.

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/454114

Thesis Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Hilbers, ML; Dimitriou, F; Lau, P et al. · 2021 · Theses · DOI

Full title: Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Authors: Hilbers, ML; Dimitriou, F; Lau, P; Bhave, P; McArthur, GA; Zimmer, L; Kudura, K; Gérard, CL; Levesque, MP; Michielin, O; Dummer, R; Cheng, PF; Mangana, J

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/289654

Thesis Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Meehan, K; Leslie, C; Lucas, M et al. · 2020 · Theses · DOI

Full title: Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Authors: Meehan, K; Leslie, C; Lucas, M; Jacques, A; Mirzai, B; Lim, J; Bulsara, M; Khan, Y; Wong, NC; Solomon, B; Sader, C; Friedland, P; Mir Arnau, G; Semple, T; Lim, AM

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/246366

Thesis VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study

Smyth, Elizabeth; Knödler, Maren; Giraut, Anne et al. · 2020 · Theses · DOI

Full title: VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study

Authors: Smyth, Elizabeth; Knödler, Maren; Giraut, Anne; Mauer, Murielle; Nilsson, Magnus; Van Grieken, Nicole; Wagner, Anna Dorothea; Moehler, Markus; Lordick, Florian

Year: 2020

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/303757

Thesis Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2020 · Theses · DOI

Full title: Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Authors: Bowyer, S; Prithviraj, P; Lorigan, P; Larkin, J; McArthur, G; Atkinson, V; Millward, M; Khou, M; Diem, S; Ramanujam, S; Kong, B; Liniker, E; Guminski, A; Parente, P; Andrews, MC; Parakh, S; Cebon, J; Long, GV; Carlino, MS; Klein, O

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/258389

Thesis Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study

Koks, Marije S; Ocak, Gurbey; Suelmann, Britt B M et al. · 2021 · Theses · DOI

Full title: Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study

Authors: Koks, Marije S; Ocak, Gurbey; Suelmann, Britt B M; Hulsbergen-Veelken, Cornelia A R; Haitjema, Saskia; Vianen, Marieke E; Verhaar, Marianne C; Kaasjager, Karin A H; Khairoun, Meriem

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442933

Thesis Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta · 2019 · Theses · DOI

Full title: Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

Authors: van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta

Year: 2019

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/390030

Thesis High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

Wang, M; Huang, YK; Kong, JCH et al. · 2020 · University of Melbourne · DOI

Full title: High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

Authors: Wang, M; Huang, YK; Kong, JCH; Sun, Y; Tantalo, DG; Aw Yeang, HX; Ying, L; Yan, F; Xu, D; Halse, H; Di Costanzo, N; Gordon, IR; Mitchell, C; Mackay, LK; Busuttil, RA; Neeson, PJ; Boussioutas, A

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/246308

Thesis Clinical trial data science to advance precision oncology

Plana, Deborah · 2022 · Theses · DOI

Full title: Clinical trial data science to advance precision oncology

Authors: Plana, Deborah

Year: 2022

Venue: Theses

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371907

Thesis Therapeutic strategies to remodel immunologically cold tumors

Wang, M; Wang, S; Desai, J et al. · 2021 · Theses · DOI

Full title: Therapeutic strategies to remodel immunologically cold tumors

Authors: Wang, M; Wang, S; Desai, J; Trapani, JA; Neeson, PJ

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/274073

Thesis Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

Liu, David V.; Liu, Derek; Jerby-Arnon, Livnat et al. · 2020 · Theses · DOI

Full title: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

Authors: Liu, David V.; Liu, Derek; Jerby-Arnon, Livnat; Vokes, Natalie I.; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Izar, Benjamin; Regev, Aviv; Van Allen, Eliezer M.

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/125847

Thesis Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Taggart, David John · 2016 · Theses · DOI

Full title: Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Authors: Taggart, David John

Year: 2016

Venue: Theses

DOI: https://etheses.whiterose.ac.uk/id/eprint/16116/1/Thesis%20.pdf

Thesis Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A et al. · 2022 · Theses · DOI

Full title: Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Authors: Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A; Cintolo-Gonzalez, Jessica; Díaz-Martínez, Marta; Ohmura, Jacqueline; Mehta, Arnav; Chien, Isabel; Frederick, Dennie T; Cohen, Sonia; Plana, Deborah; Johnson, Douglas; Flaherty, Keith T; Sullivan, Ryan J; Kellis, Manolis; Boland, Genevieve M

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/132258.2

Thesis Immunosurveillance in clinical cancer management

Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M. et al. · 2024 · Theses · DOI

Full title: Immunosurveillance in clinical cancer management

Authors: Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M.; Galluzzi, Lorenzo

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/454448

Thesis Clinical pharmacology of anticancer agents with focus on neuro-oncology and biomarker assessment

van Bussel, Mark Theodorus Johannes · 2019 · Theses · DOI

Full title: Clinical pharmacology of anticancer agents with focus on neuro-oncology and biomarker assessment

Authors: van Bussel, Mark Theodorus Johannes

Year: 2019

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/383740

Thesis Induction therapy with ipilimumab and nivolumab followed by consolidative chemoradiation as organ-sparing treatment in urothelial bladder cancer: study protocol of the INDIBLADE trial

Stockem, C. F.; Mellema, J. J.J.; van Rhijn, B. W.G. et al. · 2023 · Theses · DOI

Full title: Induction therapy with ipilimumab and nivolumab followed by consolidative chemoradiation as organ-sparing treatment in urothelial bladder cancer: study protocol of the INDIBLADE trial

Authors: Stockem, C. F.; Mellema, J. J.J.; van Rhijn, B. W.G.; Boellaard, T. N.; van Montfoort, M. L.; Balduzzi, S.; Boormans, J. L.; Franckena, M.; Meijer, R. P.; Robbrecht, D. G.J.; Suelmann, B. B.M.; Schaake, E. E.; van der Heijden, M. S.

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/450053

Thesis Activated osteoarthritis following immune checkpoint inhibitor treatment: An observational study

Reid, P; Liew, DFL; Akruwala, R et al. · 2021 · Theses · DOI

Full title: Activated osteoarthritis following immune checkpoint inhibitor treatment: An observational study

Authors: Reid, P; Liew, DFL; Akruwala, R; Bass, AR; Chan, KK

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/289729

Thesis Hematologic malignancies following immune checkpoint inhibition for solid tumors

van Eijs, Mick J.M.; van der Wagen, Lotte E.; Mous, Rogier et al. · 2023 · Utrecht University · DOI

Full title: Hematologic malignancies following immune checkpoint inhibition for solid tumors

Authors: van Eijs, Mick J.M.; van der Wagen, Lotte E.; Mous, Rogier; Leguit, Roos J.; van de Corput, Lisette; van Lindert, Anne S.R.; Suelmann, Britt B.M.; Kamphuis, Anna M.; Nierkens, Stefan; Suijkerbuijk, Karijn P.M.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/446549

Thesis The Biological and Immunological Effects of Irreversible Electroporation and Combination Therapy Options for the Improving the Treatment of Pancreatic Cancer

Brock, Rebecca Michaela · 2020 · Theses · DOI

Full title: The Biological and Immunological Effects of Irreversible Electroporation and Combination Therapy Options for the Improving the Treatment of Pancreatic Cancer

Authors: Brock, Rebecca Michaela

Year: 2020

Venue: Theses

DOI: http://hdl.handle.net/10919/98775

Thesis A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Heinhuis, Kimberley Marga · 2020 · Theses · DOI

Full title: A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Authors: Heinhuis, Kimberley Marga

Year: 2020

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/400086

Thesis Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report

Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak et al. · 2025 · Theses · DOI

Full title: Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report

Authors: Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak; Larkin, James; Powles, Tom; Stewart, Grant D; Albiges, Laurence; Bex, Axel; Choueiri, Toni K; Davis, Ian D; Eisen, Tim; Fielding, Alison; Gedye, Craig; Harrison, David J; Kaplan, Rick; Mulhere, Salena; Nathan, Paul; Patel, Grisma; Patel, Jay; Plant, Hannah; Ritchie, Alastair; Rush, Hannah; Shakeshaft, Clare; Stockler, Martin R; Suarez, Cristina; Thompson, Jemima; Thorogood, Nat; Venugopal, Balaji; Parmar, Mahesh KB

Year: 2025

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/378106

Thesis Association of good oncological response to therapy with the development of rheumatic immune-related adverse events following PD-1 inhibitor therapy

Liew, DFL; Leung, JLY; Liu, B et al. · 2021 · Theses · DOI

Full title: Association of good oncological response to therapy with the development of rheumatic immune-related adverse events following PD-1 inhibitor therapy

Authors: Liew, DFL; Leung, JLY; Liu, B; Cebon, J; Frauman, AG; Buchanan, RRC

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/284891

Thesis Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Saleh, R; Toor, SM; Al-Ali, D et al. · 2021 · Theses · DOI

Full title: Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Authors: Saleh, R; Toor, SM; Al-Ali, D; Sasidharan Nair, V; Elkord, E

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277709

Thesis Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Mangsbo, Sara · 2009 · Theses · DOI

Full title: Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Authors: Mangsbo, Sara

Year: 2009

Venue: Theses

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110147

Thesis Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander et al. · 2020 · Theses · DOI

Full title: Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Authors: Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander; Morrison, Ryan D; O’Neill Reising, Leslie; Ackermann, Bradley L; Fill, Jeff A; Schade, Andrew E; Gruver, Aaron M

Year: 2020

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3091687/1/Analysis.pdf

Thesis The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study

Holmberg, CJ; Ny, L; Hieken, TJ et al. · 2022 · Theses · DOI

Full title: The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study

Authors: Holmberg, CJ; Ny, L; Hieken, TJ; Block, MS; Carr, MJ; Sondak, VK; Örtenwall, C; Katsarelias, D; Dimitriou, F; Menzies, AM; Saw, RP; Rogiers, A; Straker, RJ; Karakousis, G; Applewaite, R; Pallan, L; Han, D; Vetto, JT; Gyorki, DE; Tie, EN; Vitale, MG; Ascierto, PA; Dummer, R; Cohen, J; Hui, JY; Schachter, J; Asher, N; Helgadottir, H; Chai, H; Kroon, H; Coventry, B; Rothermel, LD; Sun, J; Carlino, MS; Duncan, Z; Broman, K; Weber, J; Lee, AY; Berman, RS; Teras, J; Ollila, DW; Long, GV; Zager, JS; van Akkooi, A; Olofsson Bagge, R

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/322130

Thesis GPCRs as Next-Gen Targets for Immune Oncology

Wu, Victoria Huannyun · 2021 · Theses · DOI

Full title: GPCRs as Next-Gen Targets for Immune Oncology

Authors: Wu, Victoria Huannyun

Year: 2021

Venue: Theses

DOI: https://escholarship.org/uc/item/75p699pz

Thesis Genomics-guided Oncology: Advancing Efficacy and Access

Zeverijn, Laurien J · 2024 · Theses · DOI

Full title: Genomics-guided Oncology: Advancing Efficacy and Access

Authors: Zeverijn, Laurien J

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/457064

Thesis New biomarkers for checkpoint inhibitor therapy

Burdett, N; Desai, J · 2021 · Theses · DOI

Full title: New biomarkers for checkpoint inhibitor therapy

Authors: Burdett, N; Desai, J

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277746

Thesis Identifying Blood-Based Biomarkers of Efficacy, Toxicity and Outcome in Early-Stage Breast Cancer

Alkhafaji, Silver · 2025 · Theses · DOI

Full title: Identifying Blood-Based Biomarkers of Efficacy, Toxicity and Outcome in Early-Stage Breast Cancer

Authors: Alkhafaji, Silver

Year: 2025

Venue: Theses

DOI: https://escholarship.org/uc/item/2bx649ss

Thesis The role of immune checkpoints in cardiovascular disease

Yousif, Laura I; Tanja, Anniek A; de Boer, Rudolf A et al. · 2022 · Theses · DOI

Full title: The role of immune checkpoints in cardiovascular disease

Authors: Yousif, Laura I; Tanja, Anniek A; de Boer, Rudolf A; Teske, Arco J; Meijers, Wouter C

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/450612

Thesis Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Regev, Aviv · 2020 · Theses · DOI

Full title: Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Authors: Regev, Aviv

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/125032

Thesis Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C et al. · 2022 · Theses · DOI

Full title: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Authors: Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C; Kim, Albert E; Klein, Robert H; Nayyar, Naema; Navia, Andrew W; Kuter, Benjamin M; Kolb, Kellie E; Bihun, Ivanna; Mora, Joana L; Bertalan, Mia Solana; Shaw, Brian; White, Michael; Kaplan, Alexander; Stocking, Jackson H; Wadsworth, Marc H; Lee, Eudocia Q; Chukwueke, Ugonma; Wang, Nancy; Subramanian, Megha; Rotem, Denisse; Cahill, Daniel P; Adalsteinsson, Viktor A; Miller, Jeffrey W; Sullivan, Ryan J; Carter, Scott L; Brastianos, Priscilla K; Shalek, Alex K

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/141282

Thesis Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Ascierto, PA; McArthur, GA · 2020 · Theses · DOI

Full title: Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Authors: Ascierto, PA; McArthur, GA

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/256879

Thesis Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William et al. · 2025 · Theses · DOI

Full title: Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Authors: Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William; Meyer, Tim; Steven, Neil; Lao, Christopher D; Fariñas-Madrid, Lorena; Devriese, Lot A; Moore, Kathleen; Ferris, Robert L; Honma, Yoshitaka; Elias, Ileana; Srirangam, Anjaiah; Garnett-Benson, Charlie; Lee, Michelle; Nghiem, Paul

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/460578

Thesis Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2021 · Theses · DOI

Full title: Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/259450

Thesis Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · Theses · DOI

Full title: Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/360026

Thesis Assessing the Effect of Combining BRAF, MEK, and Immune Checkpoint Inhibitors on the Immune Response to Cutaneous Melanoma

Patel, Riyaben Pankajkumar · 2024 · Theses · DOI

Full title: Assessing the Effect of Combining BRAF, MEK, and Immune Checkpoint Inhibitors on the Immune Response to Cutaneous Melanoma

Authors: Patel, Riyaben Pankajkumar

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/354845

Thesis Five latent factors underlie response to immunotherapy

Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A. et al. · 2024 · Theses · DOI

Full title: Five latent factors underlie response to immunotherapy

Authors: Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A.; Batlle, Eduard; Carles, Joan; Cuppen, Edwin; Elez, Elena; Felip, Enriqueta; Gómez-Rey, Marina; Lo Giacco, Deborah; Martinez-Jimenez, Francisco; Muñoz-Couselo, Eva; Siu, Lillian L.; Tabernero, Josep; Vivancos, Ana; Muiños, Ferran; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/458268

Thesis Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events-A Comprehensive Review

Hommes, Josefien W; Verheijden, Rik J; Suijkerbuijk, Karijn P M et al. · 2021 · Theses · DOI

Full title: Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events-A Comprehensive Review

Authors: Hommes, Josefien W; Verheijden, Rik J; Suijkerbuijk, Karijn P M; Hamann, Dörte

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442368

Thesis Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Spranger-Zimmermann, Stefani · 2020 · Theses · DOI

Full title: Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Authors: Spranger-Zimmermann, Stefani

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/126367

Thesis Immune landscape of breast tumors with low and intermediate estrogen receptor expression

Voorwerk, Leonie; Sanders, Joyce; Keusters, Milou S. et al. · 2023 · Utrecht University · DOI

Full title: Immune landscape of breast tumors with low and intermediate estrogen receptor expression

Authors: Voorwerk, Leonie; Sanders, Joyce; Keusters, Milou S.; Balduzzi, Sara; Cornelissen, Sten; Duijst, Maxime; Lips, Esther H.; Sonke, Gabe S.; Linn, Sabine C.; Horlings, Hugo M.; Kok, Marleen

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/459152

Thesis Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Lau, PKH; Feran, B; Smith, L et al. · 2022 · Theses · DOI

Full title: Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Authors: Lau, PKH; Feran, B; Smith, L; Lasocki, A; Molania, R; Smith, K; Weppler, A; Angel, C; Kee, D; Bhave, P; Lee, B; Young, RJ; Iravani, A; Yeang, HA; Vergara, IA; Kok, D; Drummond, K; Neeson, PJ; Sheppard, KE; Papenfuss, T; Solomon, BJ; Sandhu, S; McArthur, GA

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/296832

Thesis Neutrophils in the era of immune checkpoint blockade

Faget, Julien; Peters, Solange; Quantin, Xavier et al. · 2021 · Theses · DOI

Full title: Neutrophils in the era of immune checkpoint blockade

Authors: Faget, Julien; Peters, Solange; Quantin, Xavier; Meylan, Etienne; Bonnefoy, Nathalie

Year: 2021

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/181353

Thesis Activity of Immunotherapy Regimens on Primary Renal Tumours: A Systematic Review

Jones, JO; Ince, WHJ; Welsh, SJ et al. · 2023 · Theses · DOI

Full title: Activity of Immunotherapy Regimens on Primary Renal Tumours: A Systematic Review

Authors: Jones, JO; Ince, WHJ; Welsh, SJ; Stewart, GD

Year: 2023

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/345156

Thesis Immune profiling of pediatric solid tumors

Terry, RL; https://orcid.org/0000-0002-6260-7372; Meyran, D et al. · 2020 · Theses · DOI

Full title: Immune profiling of pediatric solid tumors

Authors: Terry, RL ; https://orcid.org/0000-0002-6260-7372; Meyran, D; Ziegler, DS ; https://orcid.org/0000-0001-7451-7916; Haber, M ; https://orcid.org/0000-0003-2036-8817; Ekert, PG ; https://orcid.org/0000-0002-2976-8617; Trapani, JA; Neeson, PJ

Year: 2020

Venue: Theses

DOI: http://hdl.handle.net/1959.4/unsworks_80081

Thesis Adjuvant therapy for stage II melanoma: the need for further studies

Lee, Rebecca; Mandala, Mario; Long, Georgina V. et al. · 2023 · Theses · DOI

Full title: Adjuvant therapy for stage II melanoma: the need for further studies

Authors: Lee, Rebecca; Mandala, Mario; Long, Georgina V.; Eggermont, Alexander M.M.; van Akkooi, Alexander C.J.; Sandhu, Shahneen; Garbe, Claus; Lorigan, Paul

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/459368

Thesis Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis

van der Leij, Stephanie; Suijkerbuijk, Karijn P M; van den Broek, Medard F M et al. · 2024 · Theses · DOI

Full title: Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis

Authors: van der Leij, Stephanie; Suijkerbuijk, Karijn P M; van den Broek, Medard F M; Valk, Gerlof D; Dankbaar, Jan Willem; van Santen, Hanneke M

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/455308

Thesis CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Millen, R; Hendry, S; Narasimhan, V et al. · 2020 · Theses · DOI

Full title: CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Authors: Millen, R; Hendry, S; Narasimhan, V; Abbott, R; Croxford, M; Gibbs, P; Tie, J; Wong, HL; Jones, I; Kosmider, S; Byrne, D; Zalcberg, J; Fox, S; Desai, J; Visvanathan, K; Ramsay, RG; Tran, B

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/247670

Thesis An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape

Anton, A; Hutchinson, R; Hovens, CM et al. · 2025 · Theses · DOI

Full title: An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape

Authors: Anton, A; Hutchinson, R; Hovens, CM; Christie, M; Ryan, A; Gibbs, P; Costello, A; Peters, J; Neeson, PJ; Corcoran, NM; Tran, B

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/359317

Thesis **Authors:** RAPUANO LEMBO, ROSA **Institution:** Università degli Studi di Milano (AIR) **Date:** 2025-12-19

RAPUANO LEMBO, ROSA · 2025 · Theses · DOI

Full title: **Authors:** RAPUANO LEMBO, ROSA **Institution:** Università degli Studi di Milano (AIR) **Date:** 2025-12-19

Authors: RAPUANO LEMBO, ROSA

Year: 2025

Venue: Theses

DOI: http://dx.doi.org/10.13130/rapuano-lembo-rosa_phd2025-12-19

Thesis Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Rashidian, Mohammad; Ingram, Jessica R.; Dougan, Michael et al. · 2018 · Theses · DOI

Full title: Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Authors: Rashidian, Mohammad; Ingram, Jessica R.; Dougan, Michael; Dongre, Anushka; Whang, Katherine A.; LeGall, Camille; Cragnolini, Juan J.; Bierie, Brian; Gostissa, Monica; Gorman, James; Grotenbreg, Gijsbert M.; Bhan, Atul; Weinberg, Robert A; Ploegh, Hidde

Year: 2018

Venue: Theses

DOI: http://hdl.handle.net/1721.1/115202

Thesis Immune checkpoint inhibitors in infectious disease

King, HAD; Lewin, SR · 2025 · University of Melbourne · DOI

Full title: Immune checkpoint inhibitors in infectious disease

Authors: King, HAD; Lewin, SR

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/358581

Thesis Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

None · 2021 · Theses · DOI

Full title: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Authors: None

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/1721.1/136118

Thesis Understanding the molecular basis of cancer immunotherapy for melanoma

Huang, Xinyao · 2025 · Theses · DOI

Full title: Understanding the molecular basis of cancer immunotherapy for melanoma

Authors: Huang, Xinyao

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/457137

Thesis Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M. et al. · 2024 · Theses · DOI

Full title: Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Authors: Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M.; Wolthuis, Esther K.; van Thienen, Johannes V.; van der Heijden, Michiel S.; Haanen, John B.A.G.; Beijnen, Jos H.; Huitema, Alwin D.R.

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/455323

Thesis Breast cancer cells and PD-1/PD-L1 blockade upregulate the expression of PD-1, CTLA-4, TIM-3 and LAG-3 immune checkpoints in CD4+ T cells

Saleh, R; Toor, SM; Khalaf, S et al. · 2021 · Theses · DOI

Full title: Breast cancer cells and PD-1/PD-L1 blockade upregulate the expression of PD-1, CTLA-4, TIM-3 and LAG-3 immune checkpoints in CD4+ T cells

Authors: Saleh, R; Toor, SM; Khalaf, S; Elkord, E

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277642

Thesis Novel Role of PPAR-Gamma in GM-CSF Induced Anti-Tumor Immunity

Goyal, Girija · 2015 · Harvard University - DASH · DOI

Full title: Novel Role of PPAR-Gamma in GM-CSF Induced Anti-Tumor Immunity

Authors: Goyal, Girija

Year: 2015

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226102

Thesis Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

Ye, Weiyu; Olsson-Brown, Anna; Watson, Robert A et al. · 2021 · Theses · DOI

Full title: Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

Authors: Ye, Weiyu; Olsson-Brown, Anna; Watson, Robert A; Cheung, Vincent TF; Morgan, Robert D; Nassiri, Isar; Cooper, Rosalin; Taylor, Chelsea A; Akbani, Umair; Brain, Oliver; Matin, Rubeta N; Coupe, Nicholas; Middleton, Mark R; Coles, Mark; Sacco, Joseph J; Payne, Miranda J; Fairfax, Benjamin P

Year: 2021

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3127126/1/Checkpoint-blocker-induced%20autoimmunity%20is%20associated%20with%20favourable%20outcome%20in%20metastatic%20melanoma%20and%20distinct%20T-cell%20exp.pdf

Thesis First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Hegewisch-Becker, S; Mendez, G; Chao, J et al. · 2025 · Theses · DOI

Full title: First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Authors: Hegewisch-Becker, S; Mendez, G; Chao, J; Nemecek, R; Feeney, K; Van Cutsem, E; Al-Batran, SE; Mansoor, W; Maisey, N; Pazo Cid, R; Burge, M; Perez-Callejo, D; Hipkin, RW; Mukherjee, S; Lei, M; Tang, H; Suryawanshi, S; Kelly, RJ; Tebbutt, NC

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/358332

Thesis Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors

Nasca, Vincenzo; Zhao, Joseph; Ros, Javier et al. · 2025 · Theses · DOI

Full title: Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors

Authors: Nasca, Vincenzo; Zhao, Joseph; Ros, Javier; Lonardi, Sara; Zwart, Koen; Cohen, Romain; Fakih, Marwan; Jayachandran, Priya; Roodhart, Jeanine M L; Derksen, Jeroen; Intini, Rossana; Bergamo, Francesca; Mazzoli, Giacomo; Ghelardi, Filippo; Ligero, Marta; Jonnagaddala, Jitendra; Hawkins, Nicholas; Ward, Robyn L; Wankhede, Durgesh; Brenner, Hermann; Hoffmeister, Michael; Vitellaro, Marco; Salvatore, Lisa; Gallois, Claire; Laurent-Puig, Pierre; Cremolini, Chiara; Overman, Michael J; Taieb, Julien; Tougeron, David; Andre, Thierry; Kather, Jakob Nikolas; Sundar, Raghav; Carmona, Javier; Elez, Elena; Koopman, Miriam; Pietrantonio, Filippo

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/460579

Thesis Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Trujillo, Jonathan A; Luke, Jason J; Zha, Yuanyuan et al. · 2020 · Theses · DOI

Full title: Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Authors: Trujillo, Jonathan A; Luke, Jason J; Zha, Yuanyuan; Segal, Jeremy P; Ritterhouse, Lauren L; Spranger-Zimmermann, Stefani; Matijevich, Karen; Gajewski, Thomas F

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/126359

Thesis Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

Aristin Revilla, Sonia; Kranenburg, Onno; Coffer, Paul J. · 2022 · Utrecht University · DOI

Full title: Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

Authors: Aristin Revilla, Sonia; Kranenburg, Onno; Coffer, Paul J.

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/453924

Thesis The delicate balance of melanoma immunotherapy

Gyorki, DE; Callahan, M; Wolchok, JD et al. · 2022 · Theses · DOI

Full title: The delicate balance of melanoma immunotherapy

Authors: Gyorki, DE; Callahan, M; Wolchok, JD; Ariyan, CE

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/304507

Thesis Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2022 · Theses · DOI

Full title: Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review

Authors: Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G; van Diest, Paul J; Pluim, Josien P W; Verhoeff, Joost J C; de Jong, Pim A; Leiner, Tim; Veta, Mitko; Suijkerbuijk, Karijn P M

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/447089

Thesis Novel biomarkers for melanoma immunotherapy

Wong, Ngai Man Annie · 2020 · Theses · DOI

Full title: Novel biomarkers for melanoma immunotherapy

Authors: Wong, Ngai Man Annie

Year: 2020

Venue: Theses

DOI: http://hdl.handle.net/11343/252887

Thesis **Authors:** Sidiropoulos, Dimitrios Nikolaos **Institution:** Johns Hopkins University **Date:** 2024-01-03T16:16:50Z

Sidiropoulos, Dimitrios Nikolaos · 2024 · Theses · DOI

Full title: **Authors:** Sidiropoulos, Dimitrios Nikolaos **Institution:** Johns Hopkins University **Date:** 2024-01-03T16:16:50Z

Authors: Sidiropoulos, Dimitrios Nikolaos

Year: 2024

Venue: Theses

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/69091

Thesis Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

van Eijs, Mick J.M.; ter Linde, José J.M.; Baars, Matthijs J.D. et al. · 2023 · Utrecht University · DOI

Full title: Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

Authors: van Eijs, Mick J.M.; ter Linde, José J.M.; Baars, Matthijs J.D.; Amini, Mojtaba; Laclé, Miangela M.; Brand, Eelco C.; Delemarre, Eveline M.; Drylewicz, Julia; Nierkens, Stefan; Verheijden, Rik J.; Oldenburg, Bas; Vercoulen, Yvonne; Suijkerbuijk, Karijn P.M.; van Wijk, Femke

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/450094

Thesis Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma

Fröhlich, A; Loick, S; Bawden, EG et al. · 2021 · Theses · DOI

Full title: Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma

Authors: Fröhlich, A; Loick, S; Bawden, EG; Fietz, S; Dietrich, J; Diekmann, E; Saavedra, G; Fröhlich, H; Niebel, D; Sirokay, J; Zarbl, R; Gielen, GH; Kristiansen, G; Bootz, F; Landsberg, J; Dietrich, D

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277648

Thesis Tarloxotinib amplifies the anti-tumour efficacy of immune checkpoint inhibitors through multiple mechanisms

Fu, Zhe · 2020 · Theses · DOI

Full title: Tarloxotinib amplifies the anti-tumour efficacy of immune checkpoint inhibitors through multiple mechanisms

Authors: Fu, Zhe

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/2292/52722

Thesis The Gut Microbiome Shapes the Tumor Microenvironment by Tuning Innate Immunity

Fessler, Jessica Lynn · 2021 · Theses · DOI

Full title: The Gut Microbiome Shapes the Tumor Microenvironment by Tuning Innate Immunity

Authors: Fessler, Jessica Lynn

Year: 2021

Venue: Theses

DOI: https://knowledge.uchicago.edu/record/2823/files/Fessler_uchicago_0330D_15632.pdf

Thesis Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

Roberts, A; Bentley, L; Tang, T et al. · 2021 · Theses · DOI

Full title: Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

Authors: Roberts, A; Bentley, L; Tang, T; Stewart, F; Pallini, C; Juvvanapudi, J; Wallace, GR; Cooper, AJ; Scott, A; Thickett, D; Lugg, ST; Bancroft, H; Hemming, B; Ferris, C; Langman, G; Robinson, A; Chapman, J; Naidu, B; Pinkney, T; Taylor, GS; Brock, K; Stamataki, Z; Brady, CA; Curnow, SJ; Gordon, J; Qureshi, O; Barnes, NM

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/273022

Thesis Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and dependent on IL23 and IFNg

Lo, Jonathan; Cozzetto, Domenico; Alexander, James et al. · 2023 · Theses · DOI

Full title: Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and dependent on IL23 and IFNg

Authors: Lo, Jonathan; Cozzetto, Domenico; Alexander, James; Danckert, Nathan; Madgwick, Matthew; Knox, Naomi; Sieh, Jillian; Olbei, marton; Liu, Zhigang; Ibraheim, Hajir; Miguens Blanco, Jesus; Kudo, Hiromi; Castro Seoane, Rocio; Possamai, Lucia; Goldin, Robert; Marchesi, Julian; Korcsmaros, Tamas; Lord, Graham; Powell, Nick

Year: 2023

Venue: Theses

DOI: https://www.nature.com/articles/s41467-023-41798-2

Thesis CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Wang, J; Li, X; Xiao, G et al. · 2024 · Theses · DOI

Full title: CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Authors: Wang, J; Li, X; Xiao, G; Desai, J; Frentzas, S; Wang, ZM; Xia, Y; Li, B

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/350752

Thesis Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Saleh, R; Taha, RZ; Toor, SM et al. · 2021 · Theses · DOI

Full title: Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Authors: Saleh, R; Taha, RZ; Toor, SM; Sasidharan Nair, V; Murshed, K; Khawar, M; Al-Dhaheri, M; Petkar, MA; Abu Nada, M; Elkord, E

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/277749

Thesis The Role of TIM-3 in Glioblastoma Progression

Ahmady, F; Sharma, A; Achuthan, AA et al. · 2025 · University of Melbourne · DOI

Full title: The Role of TIM-3 in Glioblastoma Progression

Authors: Ahmady, F; Sharma, A; Achuthan, AA; Kannourakis, G; Luwor, RB

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360090

Thesis Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP] et al. · 2025 · Theses · DOI

Full title: Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Authors: Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP]; Dias, Queila Cristina; Pinheiro Fantinatti, Alexandra; Fávaro, Wagner José

Year: 2025

Venue: Theses

DOI: http://dx.doi.org/10.3390/ani13121888

Thesis Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Carbone, DP; Ciuleanu, TE; Schenker, M et al. · 2024 · Theses · DOI

Full title: Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Authors: Carbone, DP; Ciuleanu, TE; Schenker, M; Cobo, M; Bordenave, S; Juan-Vidal, O; Menezes, J; Reinmuth, N; Richardet, E; Cheng, Y; Mizutani, H; Felip, E; Zurawski, B; Alexandru, A; Paz-Ares, L; Lu, S; John, T; Zhang, X; Mahmood, J; Hu, N; De, T; Santi, I; Penrod, JR; Yuan, Y; Lee, A; Reck, M

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/352762

Thesis Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

Naik, Girish; Waikar, Sushrut S.; Johnson, Alistair Edward William et al. · 2020 · Theses · DOI

Full title: Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

Authors: Naik, Girish; Waikar, Sushrut S.; Johnson, Alistair Edward William; Buchbinder, Elizabeth I.; Haq, Rizwan; Hodi, F. Stephen; Schoenfeld, Jonathan D.; Ott, Patrick A.

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/124317

Thesis Active immunization with a Her-2/neu-targeting Multi-peptide B cell vaccine prevents lung metastases formation from Her-2/neu breast cancer in a mouse model

Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Drinić, Mirjana (Medical University of Vienna) et al. · 2022 · University of Veterinary Medicine Vienna (Vetmeduni Vienna) · DOI

Full title: Active immunization with a Her-2/neu-targeting Multi-peptide B cell vaccine prevents lung metastases formation from Her-2/neu breast cancer in a mouse model

Authors: Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Drinić, Mirjana (Medical University of Vienna); Högler, Sandra (University of Veterinary Medicine Vienna); Baier, Karin (Medical University of Vienna); Ambroz, Katharina (Medical University of Vienna); Zielinski, Christoph C. (Wiener Privatklinik / Central European Cooperative Oncology Group); Kundi, Michael (Medical University of Vienna); Kenner, Lukas (University of Veterinary Medicine, Vienna / Medical University Vienna); Garner-Spitzer, Erika (Medical University of Vienna); Schmid, Anna (Medical University of Vienna); Berghoff, Anna S. (Medical University of Vienna); Tomasich, Erwin (Medical University of Vienna); Kodajova, Petra (University of Veterinary Medicine Vienna)

Year: 2022

Venue: University of Veterinary Medicine Vienna (Vetmeduni Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:1804

Thesis The study on myeloid-derived suppressor cells (MDSCs) and T cells in melanoma patients with adverse events after immunotherapy immune checkpoint inhibitors

Lepper, Alisa Helen · 2025 · Theses · DOI

Full title: The study on myeloid-derived suppressor cells (MDSCs) and T cells in melanoma patients with adverse events after immunotherapy immune checkpoint inhibitors

Authors: Lepper, Alisa Helen

Year: 2025

Venue: Theses

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/36613/1/Doktorarbeit_Alisa_Lepper_Version_zur_Abgabe.pdf

Thesis Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Veinalde, Rūta · 2017 · Theses · DOI

Full title: Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Authors: Veinalde, Rūta

Year: 2017

Venue: Theses

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/23094/1/R.Veinalde_Thesis_print.pdf

Thesis Tumor immunosurveiliance: Innate immune activation as a mechanistic prerequisite for efficient immune checkpoint blockade in cancer immunotherapy

Wintges, Alexander F. G. · 2018 · Theses · DOI

Full title: Tumor immunosurveiliance: Innate immune activation as a mechanistic prerequisite for efficient immune checkpoint blockade in cancer immunotherapy

Authors: Wintges, Alexander F. G.

Year: 2018

Venue: Theses

DOI: https://mediatum.ub.tum.de/1436586

Thesis Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Ahern, E; Solomon, BJ; Hui, R et al. · 2021 · Theses · DOI

Full title: Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Authors: Ahern, E; Solomon, BJ; Hui, R; Pavlakis, N; O'Byrne, K; Hughes, BGM

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/287197

Thesis Case of nivolumab-induced sclerosing cholangitis: Lessons from long-term follow-up

McClure, T; Cui, W; Asadi, K et al. · 2020 · Theses · DOI

Full title: Case of nivolumab-induced sclerosing cholangitis: Lessons from long-term follow-up

Authors: McClure, T; Cui, W; Asadi, K; John, T; Testro, A

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/252197

Thesis Long-Term Survival in Patients With Advanced Melanoma

van Not, Olivier J; van den Eertwegh, Alfons J M; Groningen, University et al. · 2024 · Theses · DOI

Full title: Long-Term Survival in Patients With Advanced Melanoma

Authors: van Not, Olivier J; van den Eertwegh, Alfons J M; Groningen, University; Bloem, Manja; Haanen, John B; van Rijn, Rozemarijn S; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; de Groot J W B, Jan Willem; Hospers, Geke A P; Kapiteijn, Ellen; Leeneman, Brenda; D, Piersma; Stevense-den Boer, Marion; van der Veldt, Astrid A M; Vreugdenhil G, Gerard; Wouters, Michel W J M; Blokx, Willeke A M; Suijkerbuijk, Karijn P M

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/455362

Thesis Immune checkpoint blockade in renal cell carcinoma

Rappold, PM; Silagy, AW; Kotecha, RR et al. · 2022 · Theses · DOI

Full title: Immune checkpoint blockade in renal cell carcinoma

Authors: Rappold, PM; Silagy, AW; Kotecha, RR; Hakimi, AA

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/298242

Thesis PD-L1 expression and prediction of response to immune modulators in non-small cell lung cancer : reasons for its fragility and strategies to reduce it

Haragan, Alexander · 2021 · Theses · DOI

Full title: PD-L1 expression and prediction of response to immune modulators in non-small cell lung cancer : reasons for its fragility and strategies to reduce it

Authors: Haragan, Alexander

Year: 2021

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3125235/1/201313407_May2021.pdf

Thesis Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance

Verheijden, Rik J; van Eijs, Mick J M; May, Anne M et al. · 2023 · Theses · DOI

Full title: Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance

Authors: Verheijden, Rik J; van Eijs, Mick J M; May, Anne M; van Wijk, Femke; Suijkerbuijk, Karijn P M

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/449140

Thesis Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Bhave, P; Pallan, L; Long, GV et al. · 2022 · Theses · DOI

Full title: Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Authors: Bhave, P; Pallan, L; Long, GV; Menzies, AM; Atkinson, V; Cohen, JV; Sullivan, RJ; Chiarion-Sileni, V; Nyakas, M; Kahler, K; Hauschild, A; Plummer, R; Trojaniello, C; Ascierto, PA; Zimmer, L; Schadendorf, D; Allayous, C; Lebbe, C; Maurichi, A; Santinami, M; Roy, S; Robert, C; Lesimple, T; Patel, S; Versluis, JM; Blank, CU; Khattak, A; Van der Westhuizen, A; Carlino, MS; Shackleton, M; Haydon, A

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/304521

Thesis Early phase clinical studies of novel immunotherapeutics in oncology

Ros, Wilhelmina · 2019 · Theses · DOI

Full title: Early phase clinical studies of novel immunotherapeutics in oncology

Authors: Ros, Wilhelmina

Year: 2019

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/384382

Thesis Uso do ipilimumabe em pacientes com melanoma metastático

Henriques, Vivian Saccomano [UNESP] · 2018 · Theses · DOI

Full title: Uso do ipilimumabe em pacientes com melanoma metastático

Authors: Henriques, Vivian Saccomano [UNESP]

Year: 2018

Venue: Theses

DOI: http://hdl.handle.net/11449/154827

Thesis Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis

Mulder, F. J.; de Ruiter, E. J.; Gielgens, T. F.B. et al. · 2025 · Theses · DOI

Full title: Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis

Authors: Mulder, F. J.; de Ruiter, E. J.; Gielgens, T. F.B.; Farshadpour, F.; de Bree, R.; van den Hout, M. F.C.M.; Kremer, B.; Willems, S. M.; Speel, E. J.M.

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/460913

Thesis Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Bhave, P; Ahmed, T; Lo, SN et al. · 2022 · Theses · DOI

Full title: Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Authors: Bhave, P; Ahmed, T; Lo, SN; Shoushtari, A; Zaremba, A; Versluis, JM; Mangana, J; Weichenthal, M; Si, L; Lesimple, T; Robert, C; Trojanello, C; Wicky, A; Heywood, R; Tran, L; Batty, K; Dimitriou, F; Stansfeld, A; Allayous, C; Schwarze, JK; Mooradian, MJ; Klein, O; Mehmi, I; Roberts-Thomson, R; Maurichi, A; Yeoh, HL; Khattak, A; Zimmer, L; Blank, CU; Ramelyte, E; Kähler, KC; Roy, S; Ascierto, PA; Michielin, O; Lorigan, PC; Johnson, DB; Plummer, R; Lebbe, C; Neyns, B; Sullivan, R; Hamid, O; Santinami, M; McArthur, GA; Haydon, AM; Long, GV; Menzies, AM; Carlino, MS

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/316921

Thesis Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

Devaud, C; John, LB; Westwood, JA et al. · 2021 · Theses · DOI

Full title: Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

Authors: Devaud, C; John, LB; Westwood, JA; Darcy, PK; Kershaw, MH

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/265570

Thesis PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Melaiu, O; Mina, M; Chierici, M et al. · 2017 · Theses · DOI

Full title: PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Authors: Melaiu, O; Mina, M; Chierici, M; Boldrini, R; Jurman, G; Romania, P; D'Alicandro, V; Benedetti, MC; Castellano, A; Liu, T ; https://orcid.org/0000-0001-6244-7316; Furlanello, C; Locatelli, F; Fruci, D

Year: 2017

Venue: Theses

DOI: http://hdl.handle.net/1959.4/unsworks_44362

Thesis Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Liu, David; Regev, Aviv · 2020 · Theses · DOI

Full title: Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Authors: Liu, David; Regev, Aviv

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/124400

Thesis Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?

Cheung, VTF; Gupta, T; Olsson-Brown, A et al. · 2020 · UNSW Sydney · DOI

Full title: Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?

Authors: Cheung, VTF; Gupta, T; Olsson-Brown, A; Subramanian, S; Sasson, SC ; https://orcid.org/0000-0002-5329-9072; Heseltine, J; Fryer, E; Collantes, E; Sacco, JJ; Pirmohamed, M; Simmons, A; Klenerman, P; Tuthill, M; Protheroe, AS; Chitnis, M; Fairfax, BP; Payne, MJ; Middleton, MR; Brain, O

Year: 2020

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_76597

Thesis Pre-operative ablative radiotherapy in combination with immunotherapy and novel agents in pancreatic cancer

Buckley, Hannah · 2024 · University of Cambridge · DOI

Full title: Pre-operative ablative radiotherapy in combination with immunotherapy and novel agents in pancreatic cancer

Authors: Buckley, Hannah

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/363822

Thesis Tumour-draining lymph nodes in head and neck cancer : immunological signatures and clinical implications

Krzysztof Piersiala (18659740) · 2024 · Karolinska Institutet · DOI

Full title: Tumour-draining lymph nodes in head and neck cancer : immunological signatures and clinical implications

Authors: Krzysztof Piersiala (18659740)

Year: 2024

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26909803

Thesis Physical activity and checkpoint inhibition: association with toxicity and survival

Verheijden, Rik J; Cabané Ballester, Anna; Smit, Karel C et al. · 2024 · Theses · DOI

Full title: Physical activity and checkpoint inhibition: association with toxicity and survival

Authors: Verheijden, Rik J; Cabané Ballester, Anna; Smit, Karel C; van Eijs, Mick J M; Bruijnen, Cheryl P; van Lindert, Anne S R; Suijkerbuijk, Karijn P M; May, Anne M

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/450548

Thesis F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Wong, A; Callahan, J; Keyaerts, M et al. · 2020 · Theses · DOI

Full title: F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Authors: Wong, A; Callahan, J; Keyaerts, M; Neyns, B; Mangana, J; Aberle, S; Herschtal, A; Fullerton, S; Milne, D; Iravani, A; McArthur, GA; Hicks, RJ

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/246372

Thesis DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

Jacobs, Marleen; Pouw, Juliëtte; Olde Nordkamp, Michel et al. · 2020 · Utrecht University · DOI

Full title: DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

Authors: Jacobs, Marleen; Pouw, Juliëtte; Olde Nordkamp, Michel; Radstake, Timothy; Leijten, Emmerik; Boes, Marianne

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/457405

Thesis A Retrospective Review and Comprehensive Tumour Profiling of Advanced Non-Melanomatous Cutaneous Spindle Cell Neoplasms Treated with Immune-Checkpoint Inhibitors

McLean, LS; Lim, AM; Angel, C et al. · 2024 · Theses · DOI

Full title: A Retrospective Review and Comprehensive Tumour Profiling of Advanced Non-Melanomatous Cutaneous Spindle Cell Neoplasms Treated with Immune-Checkpoint Inhibitors

Authors: McLean, LS; Lim, AM; Angel, C; Young, RJ; Pizzolla, A; Archer, S; Solomon, BJ; Thai, AA; Lewin, J; Rischin, D

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/345505

Thesis Mechanistic Elucidation and Therapeutic Improvement of Anti-CTLA-4 Therapies

Lax, Brianna Marie · 2023 · Theses · DOI

Full title: Mechanistic Elucidation and Therapeutic Improvement of Anti-CTLA-4 Therapies

Authors: Lax, Brianna Marie

Year: 2023

Venue: Theses

DOI: https://hdl.handle.net/1721.1/151592

Thesis Programmed Death-Ligand 1 Copy Number Loss in NSCLC Associates With Reduced Programmed Death-Ligand 1 Tumor Staining and a Cold Immunophenotype

Aujla, S; Aloe, C; Vannitamby, A et al. · 2022 · Theses · DOI

Full title: Programmed Death-Ligand 1 Copy Number Loss in NSCLC Associates With Reduced Programmed Death-Ligand 1 Tumor Staining and a Cold Immunophenotype

Authors: Aujla, S; Aloe, C; Vannitamby, A; Hendry, S; Rangamuwa, K; Wang, H; Vlahos, R; Selemidis, S; Leong, T; Steinfort, D; Bozinovski, S

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/308995

Thesis T-cell surveillance of therapy-induced senescent lymphoma cells in the presence of anti-CD19/CD20 × CD3 bispecific antibodies

Cai, Xiurong · 2023 · Freie Universität Berlin (Refubium) · DOI

Full title: T-cell surveillance of therapy-induced senescent lymphoma cells in the presence of anti-CD19/CD20 × CD3 bispecific antibodies

Authors: Cai, Xiurong

Year: 2023

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/40608

Thesis 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr. et al. · 2024 · Theses · DOI

Full title: 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Authors: Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr.; Gallagher, Professor Ferdia; Menih, Ines Horvat, Dr.; Mossop, Helen, Dr.; Wason, Professor James; Easita, Farhana; Thomas, Martin, Dr.; Welsh, Sarah, Dr.; Mitchell, Mr Tom; Ursprung, Stephan, Dr.; O’Carrigan, Brent, Dr.

Year: 2024

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/372324

Thesis Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

Fleury, Michelle; Belkina, Anna C; Proctor, Elizabeth A et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

Authors: Fleury, Michelle; Belkina, Anna C; Proctor, Elizabeth A; Zammitti, Christopher; Simms, Robert W; Lauffenburger, Douglas A; Snyder-Cappione, Jennifer E; Lafyatis, Robert; Dooms, Hans

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/134856.2

Thesis Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Arriola, Edurne; Wheater, Matthew; Galea, Ian et al. · 2016 · Theses · DOI

Full title: Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Authors: Arriola, Edurne; Wheater, Matthew; Galea, Ian; Cross, Nadia; Maishman, Tom; Hamid, Debbie; Stanton, Louise; Cave, Judith; Geldart, Tom; Mulatero, Clive; Potter, Vannessa; Danson, Sarah; Woll, Pennella J; Griffiths, Richard; Nolan, Luke; Ottensmeier, Christian

Year: 2016

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3169669/1/Outcome%20and%20Biomarker%20Analysis%20from%20a%20Multicenter%20Phase%202%20Study%20of%20Ipilimumab%20in%20Combination%20with%20Carboplatin%20and%20Etoposide%20.pdf

Thesis Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A; Villaudy, Julien et al. · 2022 · Theses · DOI

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Authors: Küçükköse, Emre; Heesters, Balthasar A; Villaudy, Julien; Verheem, André; Cercel, Madalina; van Hal, Susan; Boj, Sylvia F; Borel Rinkes, Inne H M; Punt, Cornelis J A; Roodhart, Jeanine M L; Laoukili, Jamila; Koopman, Miriam; Spits, Hergen; Kranenburg, Onno

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/448076

Thesis Perspectives on the role of "-Omics" in predicting response to immunotherapy

Di Giacomo, Anna Maria; Subudhi, Sumit; Vos, Wim et al. · 2025 · Theses · DOI

Full title: Perspectives on the role of "-Omics" in predicting response to immunotherapy

Authors: Di Giacomo, Anna Maria; Subudhi, Sumit; Vos, Wim; Andreatta, Massimo; Carmona, Santiago; McTavish, Will; Seliger, Barbara; Ibrahim, Ramy; Lahn, Michael; Smith, Michael; Eggermont, Alexander; Fox, Bernard A; Maio, Michele

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/460980

Thesis **Authors:** Jallad, Mary-Ann **Institution:** American University of Beirut **Date:** 2020-12-29T07:39:17Z

Jallad, Mary-Ann · 2020 · Theses · DOI

Full title: **Authors:** Jallad, Mary-Ann **Institution:** American University of Beirut **Date:** 2020-12-29T07:39:17Z

Authors: Jallad, Mary-Ann

Year: 2020

Venue: Theses

DOI: http://hdl.handle.net/10938/22166

Thesis Cost-effectiveness and financial risks associated with immune checkpoint inhibitor therapy

Kim, H; Liew, D; Goodall, S · 2021 · Theses · DOI

Full title: Cost-effectiveness and financial risks associated with immune checkpoint inhibitor therapy

Authors: Kim, H; Liew, D; Goodall, S

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/275928

Thesis Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · Theses · DOI

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/359086

Thesis Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

Colombo, AR; Hav, M; Singh, M et al. · 2022 · Theses · DOI

Full title: Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

Authors: Colombo, AR; Hav, M; Singh, M; Xu, A; Gamboa, A; Lemos, T; Gerdtsson, E; Chen, D; Houldsworth, J; Shaknovich, R; Aoki, T; Chong, L; Takata, K; Chavez, EA; Steidl, C; Hicks, J; Kuhn, P; Siddiqi, I; Merchant, A

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/318236

Thesis Defining the tumour microenvironment landscape of melanoma immunotherapy

Bai, Xinyu · 2025 · Theses · DOI

Full title: Defining the tumour microenvironment landscape of melanoma immunotherapy

Authors: Bai, Xinyu

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/2123/33848

Thesis Tumor-infiltrating lymphocytes and immune-related adverse events in advanced melanoma

van Duin, I. A.J.; Schuiveling, M.; ter Maat, L. S. et al. · 2024 · Theses · DOI

Full title: Tumor-infiltrating lymphocytes and immune-related adverse events in advanced melanoma

Authors: van Duin, I. A.J.; Schuiveling, M.; ter Maat, L. S.; Veta, M.; van Eijs, M. J.M.; Verheijden, R. J.; van den Berkmortel, F. W.P.J.; Boers-Sonderen, M. J.; Hospers, G. A.P.; Labots, M.; de Groot, J. W.B.; Kapiteijn, E.; Piersma, D.; Vreugdenhil, G.; Westgeest, H.; Schrader, A. M.R.; van Diest, P. J.; Blokx, W. A.M.; Suijkerbuijk, K. P.M.

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/454112

Thesis Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Long, GV; Shklovskaya, E; Satgunaseelan, L et al. · 2025 · Theses · DOI

Full title: Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Authors: Long, GV; Shklovskaya, E; Satgunaseelan, L; Mao, Y; da Silva, IP; Perry, KA; Diefenbach, RJ; Gide, TN; Shivalingam, B; Buckland, ME; Gonzalez, M; Caixeiro, N; Vergara, IA; Bai, X; Rawson, RV; Hsiao, E; Palendira, U; Phan, TG; Menzies, AM; Carlino, MS; Quek, C; Grimmond, SM; Vissers, JHA; Yeo, D; Rasko, JEJ; Khasraw, M; Neyns, B; Reardon, DA; Ashley, DM; Wheeler, H; Back, M; Scolyer, RA; Drummond, J; Wilmott, JS; Rizos, H

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/360002

Thesis Checkpoint Genes at the Cancer Side of the Immunological Synapse in Bladder Cancer

Dobosz, Paula; Stempor, Przemysław A; Roszik, Jason et al. · 2020 · Theses · DOI

Full title: Checkpoint Genes at the Cancer Side of the Immunological Synapse in Bladder Cancer

Authors: Dobosz, Paula; Stempor, Przemysław A; Roszik, Jason; Herman, Amir; Layani, Adi; Berger, Raanan; Avni, Dror; Sidi, Yechezkel; Leibowitz-Amit, Raya

Year: 2020

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/301473

Thesis Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

Halse, H; Colebatch, AJ; Petrone, P et al. · 2020 · University of Melbourne · DOI

Full title: Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

Authors: Halse, H; Colebatch, AJ; Petrone, P; Henderson, MA; Mills, JK; Snow, H; Westwood, JA; Sandhu, S; Raleigh, JM; Behren, A; Cebon, J; Darcy, PK; Kershaw, MH; McArthur, GA; Gyorki, DE; Neeson, PJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/251140

Thesis Understanding and Overcoming the Non-T cell-inflamed Tumor Microenvironment

Higgs, Emily Faye · 2022 · Theses · DOI

Full title: Understanding and Overcoming the Non-T cell-inflamed Tumor Microenvironment

Authors: Higgs, Emily Faye

Year: 2022

Venue: Theses

DOI: https://knowledge.uchicago.edu/record/3592/files/Higgs_uchicago_0330D_16081.pdf

Thesis Further Knowledge and Developments in Resistance Mechanisms to Immune Checkpoint Inhibitors

Berland, Lea; Gabr, Zeina; Chang, Michelle et al. · 2025 · Theses · DOI

Full title: Further Knowledge and Developments in Resistance Mechanisms to Immune Checkpoint Inhibitors

Authors: Berland, Lea; Gabr, Zeina; Chang, Michelle; Ilie, Marius I; Hofman, Veronique; Rignol, Guylene; GHIRINGHELLI, Francois; Mograbi, Baharia; Rashidian, M.; Hofman, Paul

Year: 2025

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/252010

Thesis Mechanisms of immune checkpoint inhibitor-induced gastrointestinal toxicities

Nahar, Kazi Jannatun · 2022 · Theses · DOI

Full title: Mechanisms of immune checkpoint inhibitor-induced gastrointestinal toxicities

Authors: Nahar, Kazi Jannatun

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/2123/29500

Thesis Evaluation des Einflusses der PD-1-Inhibition auf die Effektivität der chimären Antigenrezeptor (CAR) T-Zelltherapie im Neuroblastom

Töws, Karin · 2022 · Theses · DOI

Full title: Evaluation des Einflusses der PD-1-Inhibition auf die Effektivität der chimären Antigenrezeptor (CAR) T-Zelltherapie im Neuroblastom

Authors: Töws, Karin

Year: 2022

Venue: Theses

DOI: https://refubium.fu-berlin.de/handle/fub188/34526

Thesis Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Duarte, JDG; Parakh, S; Andrews, MC et al. · 2020 · Theses · DOI

Full title: Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Authors: Duarte, JDG; Parakh, S; Andrews, MC; Woods, K; Pasam, A; Tutuka, C; Ostrouska, S; Blackburn, JM; Behren, A; Cebon, J

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/256187

Thesis Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study

Wells, JC; Dudani, S; Gan, CL et al. · 2021 · Theses · DOI

Full title: Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study

Authors: Wells, JC; Dudani, S; Gan, CL; Stukalin, I; Azad, AA; Liow, E; Donskov, F; Yuasa, T; Pal, SK; De Velasco, G; Hansen, AR; Beuselinck, B; Kollmannsberger, CK; Powles, T; McGregor, BA; Duh, MS; Huynh, L; Heng, DYC

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/288773

Thesis Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

Dranoff, Glenn; Kwan, Byron Hua; Zhu, Eric Franklin et al. · 2018 · Theses · DOI

Full title: Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

Authors: Dranoff, Glenn; Kwan, Byron Hua; Zhu, Eric Franklin; Tzeng, Alice; Sugito, Harun R.; Eltahir, Ahmed A.; Ma, Botong; Delaney, Mary K.; Murphy, Patrick A.; Kauke, Monique Jacqueline; Angelini, Alessandro; Momin, Noor; Mehta, Naveen; Maragh, Alecia M.; Hynes, Richard O.; Cochran, Jennifer R.; Wittrup, Karl Dane

Year: 2018

Venue: Theses

DOI: http://hdl.handle.net/1721.1/114593

Thesis Antibody-based immunotherapy of cancer : From optimization to novel approaches

van Hooren, Luuk · 2018 · Theses · DOI

Full title: Antibody-based immunotherapy of cancer : From optimization to novel approaches

Authors: van Hooren, Luuk

Year: 2018

Venue: Theses

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342799

Thesis Exploring germline contribution to response and toxicity to treatment with anti-PD-1/PD-L1 for non-small cell lung cancer by whole genome sequencing

Barnet, Megan; https://orcid.org/0000-0003-3243-2716 · 2021 · Theses · DOI

Full title: Exploring germline contribution to response and toxicity to treatment with anti-PD-1/PD-L1 for non-small cell lung cancer by whole genome sequencing

Authors: Barnet, Megan ; https://orcid.org/0000-0003-3243-2716

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/1959.4/100563

Thesis Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Pühl, Miriam · 2024 · Theses · DOI

Full title: Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Authors: Pühl, Miriam

Year: 2024

Venue: Theses

DOI: https://refubium.fu-berlin.de/handle/fub188/40924

Thesis Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies, Mikhail; Roberts, Edward W.; Kersten, Kelly et al. · 2018 · Theses · DOI

Full title: Understanding the tumor immune microenvironment (TIME) for effective therapy

Authors: Binnewies, Mikhail; Roberts, Edward W.; Kersten, Kelly; Chan, Vincent; Fearon, Douglas F.; Merad, Miriam; Coussens, Lisa M.; Gabrilovich, Dmitry I.; Ostrand-Rosenberg, Suzanne; Hedrick, Catherine C.; Vonderheide, Robert H.; Pittet, Mikael J.; Jain, Rakesh K.; Zou, Weiping; Howcroft, T. Kevin; Woodhouse, Elisa C.; Krummel, Matthew F.; Weinberg, Robert A

Year: 2018

Venue: Theses

DOI: http://hdl.handle.net/1721.1/119415

Thesis NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy

Cazzetta, Valentina; Depierreux, Delphine; Colucci, Francesco et al. · 2023 · Theses · DOI

Full title: NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy

Authors: Cazzetta, Valentina; Depierreux, Delphine; Colucci, Francesco; Mikulak, Joanna; Mavilio, Domenico

Year: 2023

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/348052

Thesis Triplet Therapy in Melanoma — Combined BRAF/MEK Inhibitors and Anti-PD-(L)1 Antibodies

Dixon-Douglas, JR; Patel, RP; Somasundram, PM et al. · 2022 · Theses · DOI

Full title: Triplet Therapy in Melanoma — Combined BRAF/MEK Inhibitors and Anti-PD-(L)1 Antibodies

Authors: Dixon-Douglas, JR; Patel, RP; Somasundram, PM; McArthur, GA

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/308250

Thesis CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2023 · Theses · DOI

Full title: CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Authors: Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G; Leiner, Tim; Verhoeff, Joost J C; Arntz, Eran R A N; Troenokarso, Max F; Blokx, Willeke A M; Isgum, Ivana; de Wit, Geraldine A; van den Berkmortel, Franchette W P J; Boers-Sonderen, Marye J; Boomsma, Martijn F; van den Eertwegh, Fons J M; de Groot, Jan Willem B; Piersma, Djura; Vreugdenhil, Art; Westgeest, Hans M; Kapiteijn, Ellen; van Diest, Paul J; Pluim, Josien P W; de Jong, Pim A; Suijkerbuijk, Karijn P M; Veta, Mitko

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/448890

Thesis Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme

Hernandez, Amanda L.; Lowther, Daniel E.; Lucca, Liliana E. et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme

Authors: Hernandez, Amanda L.; Lowther, Daniel E.; Lucca, Liliana E.; Lerner, Benjamin A.; Gunel, Murat; Raddassi, Khadir; Coric, Vlad; Hafler, David A.; Thomas, Brittany A.; Love, John C

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/111673

Thesis Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review

Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth · 2022 · Theses · DOI

Full title: Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review

Authors: Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth

Year: 2022

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/343973

Thesis A gut microbial signature for combination immune checkpoint blockade across cancer types

Gunjur, A; Shao, Y; Rozday, T et al. · 2024 · Theses · DOI

Full title: A gut microbial signature for combination immune checkpoint blockade across cancer types

Authors: Gunjur, A; Shao, Y; Rozday, T; Klein, O; Mu, A; Haak, BW; Markman, B; Kee, D; Carlino, MS; Underhill, C; Frentzas, S; Michael, M; Gao, B; Palmer, J; Cebon, J; Behren, A; Adams, DJ; Lawley, TD

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/353256

Thesis Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab – study protocol

Janssen, J. C.; van Dijk, B.; de Joode, K. et al. · 2024 · Theses · DOI

Full title: Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab – study protocol

Authors: Janssen, J. C.; van Dijk, B.; de Joode, K.; Aarts, M. J.B.; van den Berkmortel, F. W.P.J.; Blank, C. U.; Boers-Sonderen, M. J.; van den Eertwegh, A. J.M.; de Groot, J. W.B.; Jalving, M.; de Jonge, M. J.A.; Joosse, A.; Kapiteijn, E.; Kamphuis-Huismans, A. M.; Naipal, K. A.T.; Piersma, D.; Rikhof, B.; Westgeest, H. M.; Vreugdenhil, G.; Oomen-de Hoop, E.; Mulder, E. E.A.P.; van der Veldt, Astrid A.M.

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/453272

Thesis The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M. et al. · 2023 · Theses · DOI

Full title: The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Authors: Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M.; Garbe, Claus; Gershenwald, Jeffrey E.; Hamid, Omid; Hauschild, Axel; Luke, Jason J.; Mehnert, Janice M.; Sosman, Jeffrey A.; Tawbi, Hussein A.; Mandalà, Mario; Testori, Alessandro; Caracò, Corrado; Osman, Iman; Puzanov, Igor

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/459059

Thesis IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Dunkel, IJ; Cohen, K; Foreman, NK et al. · 2022 · Theses · DOI

Full title: IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Authors: Dunkel, IJ; Cohen, K; Foreman, NK; Hargrave, D; Lassaletta, A; André, N; Hansford, JR; Hassall, T; Eyrich, M; Gururangan, S; Bartels, U; Gajjar, A; Howell, L; Warad, D; Pacius, M; Tam, R; Wang, Y; Zhu, L; Doz, F

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/318235

Thesis Predicting immunotherapy outcomes in advanced melanoma: Clinical, radiological, and pathological approaches

van Duin, Belle · 2025 · Theses · DOI

Full title: Predicting immunotherapy outcomes in advanced melanoma: Clinical, radiological, and pathological approaches

Authors: van Duin, Belle

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/457130

Thesis Immunotherapy for gastric cancer: Time for a personalized approach?

Dolcetti, R; De Re, V; Canzonieri, V · 2021 · Theses · DOI

Full title: Immunotherapy for gastric cancer: Time for a personalized approach?

Authors: Dolcetti, R; De Re, V; Canzonieri, V

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/272157

Thesis The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

Thompson, Nicola A; Stewart, Grant D; Welsh, Sarah J et al. · 2022 · Theses · DOI

Full title: The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

Authors: Thompson, Nicola A; Stewart, Grant D; Welsh, Sarah J; Doherty, Gary J; Robinson, Matthew J; Neville, B Anne; Vervier, Kevin; Harris, Simon R; Adams, David J; Dalchau, Katy; Bruce, David; Demiris, Nikolaos; Lawley, Trevor D; Corrie, Pippa G

Year: 2022

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/334470

Thesis Photon versus carbon ion radiotherapy – combining radiotherapy with immune checkpoint blockade in the EO771 breast cancer model

Hartmann, Laura · 2022 · Theses · DOI

Full title: Photon versus carbon ion radiotherapy – combining radiotherapy with immune checkpoint blockade in the EO771 breast cancer model

Authors: Hartmann, Laura

Year: 2022

Venue: Theses

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/30065/7/Laura_Hartmann_PhD_Thesis.pdf

Thesis Prognostická rola kontrolných bodov imunitných reakcií u pacientok s ovariálnym karcinómom

Raková, Jana · 2019 · Theses · DOI

Full title: Prognostická rola kontrolných bodov imunitných reakcií u pacientok s ovariálnym karcinómom

Authors: Raková, Jana

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/20.500.11956/98153

Thesis A prediction model for response to immune checkpoint inhibition in advanced melanoma

van Duin, Isabella A J; Verheijden, Rik J; van Diest, Paul J et al. · 2024 · Theses · DOI

Full title: A prediction model for response to immune checkpoint inhibition in advanced melanoma

Authors: van Duin, Isabella A J; Verheijden, Rik J; van Diest, Paul J; Blokx, Willeke A M; El-Sharouni, Mary-Ann; Verhoeff, Joost J C; Leiner, Tim; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; van Not, Olivier J; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Haanen, John B A G; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Stevense-den Boer, Marion A M; Boers-Sonderen, Marye J; Kapiteijn, Ellen; Suijkerbuijk, Karijn P M; Elias, Sjoerd G

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/451246

Thesis A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens

Lee, YH; Huang, CY; Hsieh, YH et al. · 2024 · Theses · DOI

Full title: A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens

Authors: Lee, YH; Huang, CY; Hsieh, YH; Yang, CH; Hung, YL; Chen, YA; Lin, YC; Lin, CH; Lee, JH; Wang, MY; Kuo, WH; Lin, YY; Lu, YS

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/351520

Thesis Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells

Gerton, Thomas J.; Green, Allen; Campisi, Marco et al. · 2023 · Theses · DOI

Full title: Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells

Authors: Gerton, Thomas J.; Green, Allen; Campisi, Marco; Chen, Minyue; Gjeci, Iliana; Mahadevan, Navin; Lee, Catherine A. A.; Mishra, Ranjan; Vo, Ha V.; Haratani, Koji; Li, Ze-Hua; Hasselblatt, Kathleen T.; Testino, Bryanna; Connor, Trevor; Lian, Christine G.; Elias, Kevin M.; Lizotte, Patrick; Ivanova, Elena V.; Barbie, David A.; Dinulescu, Daniela M.

Year: 2023

Venue: Theses

DOI: https://hdl.handle.net/1721.1/152071

Thesis Production of Preclinical Grade Recombinant Newcastle disease viruses to Enhance Tumor Specific Immune Responses in Syngeneic Mouse Models of Cancer

Santry, Lisa · 2018 · University of Guelph · DOI

Full title: Production of Preclinical Grade Recombinant Newcastle disease viruses to Enhance Tumor Specific Immune Responses in Syngeneic Mouse Models of Cancer

Authors: Santry, Lisa

Year: 2018

Venue: University of Guelph

DOI: http://hdl.handle.net/10214/12313

Thesis Faktory ovplyvňujúce účinnosť protinádorovej terapie blokujúcej signalizačnú dráhu PD-1/PD-L1 a prediktívne biomarkery tejto liečby

Majerová, Miriam · 2019 · Theses · DOI

Full title: Faktory ovplyvňujúce účinnosť protinádorovej terapie blokujúcej signalizačnú dráhu PD-1/PD-L1 a prediktívne biomarkery tejto liečby

Authors: Majerová, Miriam

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/20.500.11956/106652

Thesis Upcoming immunotherapeutic combinations for B-cell lymphoma

Greve, Patrick; Meyer Wentrup, Friederike; Peperzak, Victor et al. · 2021 · Theses · DOI

Full title: Upcoming immunotherapeutic combinations for B-cell lymphoma

Authors: Greve, Patrick; Meyer Wentrup, Friederike; Peperzak, Victor; Boes, Marianne

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442691

Thesis Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Klein, O; Senko, C; Carlino, MS et al. · 2022 · Theses · DOI

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Authors: Klein, O; Senko, C; Carlino, MS; Markman, B; Jackett, L; Gao, B; Lum, C; Kee, D; Behren, A; Palmer, J; Cebon, J

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/11343/304665

Thesis SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, A; Iravani, A; Lasocki, A et al. · 2021 · Theses · DOI

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, A; Iravani, A; Lasocki, A; Wallace, R; Weppler, A; Au-Yeung, G; Sachithanandan, N; Chiang, CY; Wentworth, J; Colman, PG; Kay, TW; Krishnamurthy, B; Sandhu, S

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/273859

Thesis Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E. et al. · 2020 · Theses · DOI

Full title: Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Authors: Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E.; Umeton, Renato; Albayrak, Adem; Subegdjo, Safiya J.; Johnson, Bruce E.; Nishino, Mizuki; Sholl, Lynette M.; Awad, Mark M.

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/1721.1/128646

Thesis Biomarker-driven Immunotherapy in Patients with Advanced Solid Tumors: Providing Access and Refining Patient Selection

Geurts, Birgit · 2024 · Theses · DOI

Full title: Biomarker-driven Immunotherapy in Patients with Advanced Solid Tumors: Providing Access and Refining Patient Selection

Authors: Geurts, Birgit

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/454625

Thesis Optimización del beneficio clínico en pacientes con tumores sólidos avanzados tratados en ensayos clínicos precoces a través del desarrollo de una herramienta pronóstica online y caracterización del patrón de respuesta hiperprogresor

Matos Garcia, Ignacio · 2022 · Theses · DOI

Full title: Optimización del beneficio clínico en pacientes con tumores sólidos avanzados tratados en ensayos clínicos precoces a través del desarrollo de una herramienta pronóstica online y caracterización del patrón de respuesta hiperprogresor

Authors: Matos Garcia, Ignacio

Year: 2022

Venue: Theses

DOI: http://hdl.handle.net/10803/675020

Thesis Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Verbrugge, I; Galli, M; Smyth, MJ et al. · 2021 · Theses · DOI

Full title: Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Authors: Verbrugge, I; Galli, M; Smyth, MJ; Johnstone, RW; Haynes, NM

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/265284

Thesis Inhibició de la via de la MAPK i efectes perifèrics de la inhibició dels moduladors immunes en melanoma metastàtic

Robert i Faja, Lídia · 2016 · Theses · DOI

Full title: Inhibició de la via de la MAPK i efectes perifèrics de la inhibició dels moduladors immunes en melanoma metastàtic

Authors: Robert i Faja, Lídia

Year: 2016

Venue: Theses

DOI: http://hdl.handle.net/10803/377432

Thesis The interplay between the microbiome and colonic immune system in checkpoint inhibitor therapy

Dehinsilu, Jacob; Sergaki, Chrysi; Amos, Gregory et al. · 2023 · Theses · DOI

Full title: The interplay between the microbiome and colonic immune system in checkpoint inhibitor therapy

Authors: Dehinsilu, Jacob; Sergaki, Chrysi; Amos, Gregory; Fontana, Vanessa; Pirmohamed, Munir

Year: 2023

Venue: Theses

DOI: https://livrepository.liverpool.ac.uk/3168737/1/frmbi-02-1061193.pdf

Thesis Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Lim, SY; Lee, JH; Welsh, SJ et al. · 2017 · Theses · DOI

Full title: Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Authors: Lim, SY; Lee, JH; Welsh, SJ; Ahn, SB; Breen, E; Khan, A ; https://orcid.org/0000-0002-5072-378X; Carlino, MS; Menzies, AM; Kefford, RF; Scolyer, RA; Long, GV; Rizos, H

Year: 2017

Venue: Theses

DOI: http://hdl.handle.net/1959.4/unsworks_79785

Thesis T Cell-Intrinsic 4-1BB Signaling Regulates Tumor-Infiltrating CD8+ T Cell Accumulation and Response to Immunotherapy

Horton, Brendan Leigh · 2019 · Theses · DOI

Full title: T Cell-Intrinsic 4-1BB Signaling Regulates Tumor-Infiltrating CD8+ T Cell Accumulation and Response to Immunotherapy

Authors: Horton, Brendan Leigh

Year: 2019

Venue: Theses

DOI: https://knowledge.uchicago.edu/record/1562/files/Horton_uchicago_0330D_14074.pdf

Thesis Biomarcadores para predição de resposta terapêutica a inibidores de checkpoint imunológico no câncer de pulmão : uma análise exploratória

Viola, Guilherme Danielski · 2022 · Theses · DOI

Full title: Biomarcadores para predição de resposta terapêutica a inibidores de checkpoint imunológico no câncer de pulmão : uma análise exploratória

Authors: Viola, Guilherme Danielski

Year: 2022

Venue: Theses

DOI: http://hdl.handle.net/10183/250253

Thesis Gut microbiome and immune checkpoint inhibitor toxicity

Verheijden, Rik J; van Eijs, Mick J M; Paganelli, Fernanda L et al. · 2025 · Theses · DOI

Full title: Gut microbiome and immune checkpoint inhibitor toxicity

Authors: Verheijden, Rik J; van Eijs, Mick J M; Paganelli, Fernanda L; Viveen, Marco C; Rogers, Malbert R C; Top, Janetta; May, Anne M; van de Wijgert, Janneke H H M; Suijkerbuijk, Karijn P M; UNICIT consortium

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/460104

Thesis Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Verheijden, Rik J; May, Anne M; Blank, Christian U et al. · 2020 · Theses · DOI

Full title: Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Authors: Verheijden, Rik J; May, Anne M; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; Boers-Sonderen, Marye J; van der Hoeven, Jacobus J M; Hospers, Geke A; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert; van der Veldt, Astrid Am; Vreugdenhil, Gerard; van Zeijl, Michiel C T; Wouters, Michel W J M; Haanen, John B A G; Kapiteijn, Ellen; Suijkerbuijk, Karijn Pm

Year: 2020

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/396657

Thesis Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Chew, HY; Dolcetti, R; Simpson, F · 2021 · Theses · DOI

Full title: Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Authors: Chew, HY; Dolcetti, R; Simpson, F

Year: 2021

Venue: Theses

DOI: https://hdl.handle.net/11343/275929

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Metadata only

Paper Desensitizing Effect of Intra-Tumoral GDF-15 on Immunotherapy in Patients With Advanced Non-Small Cell Lung Cancer.

Nishioka, Naoya, Naito, Tateaki, Sugino, Takashi, Muramatsu, Koji, Nishihara, Shigeki, Urashima, Hiroki, Mamesaya, Nobuaki, Kobayashi, Haruki, Omori, Shota, Ko, Ryo, Wakuda, Kazushige, Ono, Akira, Kenmotsu, Hirotsugu, Murakami, Haruyasu, Takahashi, Toshiaki · 2025 · Thoracic cancer · DOI

Full title: Desensitizing Effect of Intra-Tumoral GDF-15 on Immunotherapy in Patients With Advanced Non-Small Cell Lung Cancer.

Authors: Nishioka, Naoya, Naito, Tateaki, Sugino, Takashi, Muramatsu, Koji, Nishihara, Shigeki, Urashima, Hiroki, Mamesaya, Nobuaki, Kobayashi, Haruki, Omori, Shota, Ko, Ryo, Wakuda, Kazushige, Ono, Akira, Kenmotsu, Hirotsugu, Murakami, Haruyasu, Takahashi, Toshiaki

Year: 2025

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.70089

Paper Progress of PD-1/PD-L1 inhibitor combination therapy in immune treatment for HER2-positive tumors.

Zhao, Sining, Qiu, Yiwu, Yuan, Meiqin, Wang, Zeng · 2024 · European journal of clinical pharmacology · DOI

Full title: Progress of PD-1/PD-L1 inhibitor combination therapy in immune treatment for HER2-positive tumors.

Authors: Zhao, Sining, Qiu, Yiwu, Yuan, Meiqin, Wang, Zeng

Year: 2024

Venue: European journal of clinical pharmacology

DOI: https://doi.org/10.1007/s00228-024-03644-2

Paper Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway

Courtney Beers, Robert L. Ilaria, J. Luke · 2026 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway

Authors: Courtney Beers, Robert L. Ilaria, J. Luke

Year: 2026

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2025-013313

Paper Nivolumab and Ipilimumab in Advanced Mismatch Repair-Deficient/Microsatellite Instability-High Noncolorectal Cancers: A Nonrandomized Clinical Trial.

Carlino, Matteo S, Gao, Bo, Michael, Michael, Marshall, Henry, Gunjur, Ashray, Chan, Howard, Zielinski, Rob, So, Jane, Harris, Samuel J, Kee, Damien, Collins, Ian M, Lam, Wei-Sen, Lyle, Megan, Underhill, Craig, Brown, Michael P, Harrup, Rosemary, Wong, Shu-Fen, Grady, John, Ballinger, Mandy, Tavancheh, Elnaz, Thomas, David M, Palmer, Jodie, Wilkie, Kylie, Cebon, Jonathan, Klein, Oliver · 2026 · JAMA oncology · DOI

Full title: Nivolumab and Ipilimumab in Advanced Mismatch Repair-Deficient/Microsatellite Instability-High Noncolorectal Cancers: A Nonrandomized Clinical Trial.

Authors: Carlino, Matteo S, Gao, Bo, Michael, Michael, Marshall, Henry, Gunjur, Ashray, Chan, Howard, Zielinski, Rob, So, Jane, Harris, Samuel J, Kee, Damien, Collins, Ian M, Lam, Wei-Sen, Lyle, Megan, Underhill, Craig, Brown, Michael P, Harrup, Rosemary, Wong, Shu-Fen, Grady, John, Ballinger, Mandy, Tavancheh, Elnaz, Thomas, David M, Palmer, Jodie, Wilkie, Kylie, Cebon, Jonathan, Klein, Oliver

Year: 2026

Venue: JAMA oncology

DOI: https://doi.org/10.1001/jamaoncol.2025.4721

Paper Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxicity for Use in Immuno-Oncology.

Autio, Karen A, Boni, Valentina, Humphrey, Rachel W, Naing, Aung · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxicity for Use in Immuno-Oncology.

Authors: Autio, Karen A, Boni, Valentina, Humphrey, Rachel W, Naing, Aung

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1457

Paper Programmed cell death-1 pathway inhibitors in genitourinary malignancies: specific side-effects and their management.

Tripathi, Abhishek, Kaymakcalan, Marina D, LeBoeuf, Nicole R, Harshman, Lauren C · 2016 · Current opinion in urology · DOI

Full title: Programmed cell death-1 pathway inhibitors in genitourinary malignancies: specific side-effects and their management.

Authors: Tripathi, Abhishek, Kaymakcalan, Marina D, LeBoeuf, Nicole R, Harshman, Lauren C

Year: 2016

Venue: Current opinion in urology

DOI: https://doi.org/10.1097/MOU.0000000000000332

Paper CTLA-4 Blockade Suppresses Progression of Residual Tumors and Improves Survival After Insufficient Radiofrequency Ablation in a Subcutaneous Murine Hepatoma Model.

Zhang, Liang, Wang, Jun, Jiang, Jinhua, Zhang, Mingming, Shen, Jialin · 2020 · Cardiovascular and interventional radiology · DOI

Full title: CTLA-4 Blockade Suppresses Progression of Residual Tumors and Improves Survival After Insufficient Radiofrequency Ablation in a Subcutaneous Murine Hepatoma Model.

Authors: Zhang, Liang, Wang, Jun, Jiang, Jinhua, Zhang, Mingming, Shen, Jialin

Year: 2020

Venue: Cardiovascular and interventional radiology

DOI: https://doi.org/10.1007/s00270-020-02505-6

Paper Immunotherapy of Melanoma: Facts and Hopes.

Weiss, Sarah A, Wolchok, Jedd D, Sznol, Mario · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Immunotherapy of Melanoma: Facts and Hopes.

Authors: Weiss, Sarah A, Wolchok, Jedd D, Sznol, Mario

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-18-1550

Paper Exploring the Role of Combination Immunotherapy in Metastatic Renal Cell Carcinoma

· Default Digital Object Group · DOI

Full title: Exploring the Role of Combination Immunotherapy in Metastatic Renal Cell Carcinoma

Venue: Default Digital Object Group

DOI: https://doi.org/10.1200/adn.21.200489

Paper Contemporaneous and upcoming trends in immunotherapy for prostate cancer: review

Samra Saleem, A. Rashid, Sarma Shehzadi, Hassan Mumtaz, Muhammad Saqib, Anan Bseiso, Alexis V. Villasenor, Adeel Ahmed, S. N. Sonia · 2023 · Annals of Medicine and Surgery · DOI

Full title: Contemporaneous and upcoming trends in immunotherapy for prostate cancer: review

Authors: Samra Saleem, A. Rashid, Sarma Shehzadi, Hassan Mumtaz, Muhammad Saqib, Anan Bseiso, Alexis V. Villasenor, Adeel Ahmed, S. N. Sonia

Year: 2023

Venue: Annals of Medicine and Surgery

DOI: https://doi.org/10.1097/ms9.0000000000001070

Paper Role of Immunotherapy in the Treatment of Squamous Cell Carcinoma of the Anal Canal

Morris, Van K., Eng, Cathy · 2018 · Journal of the National Comprehensive Cancer Network · DOI

Full title: Role of Immunotherapy in the Treatment of Squamous Cell Carcinoma of the Anal Canal

Authors: Morris, Van K., Eng, Cathy

Year: 2018

Venue: Journal of the National Comprehensive Cancer Network

DOI: https://doi.org/10.6004/jnccn.2018.7040

Paper eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Postovit, Lynne‐Marie · 2024 · DOI

Full title: eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: Postovit, Lynne‐Marie

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2.sa3

Paper Volume increase of spleen in melanoma patients undergoing immune checkpoint blockade.

Susok, Laura, Reinert, Dominik, Lukas, Carsten, Stockfleth, Eggert, Gambichler, Thilo · 2021 · Immunotherapy · DOI

Full title: Volume increase of spleen in melanoma patients undergoing immune checkpoint blockade.

Authors: Susok, Laura, Reinert, Dominik, Lukas, Carsten, Stockfleth, Eggert, Gambichler, Thilo

Year: 2021

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2021-0022

Paper Genomic Sequencing for Bladder Urothelial Carcinoma and Its Clinical Implications for Immunotherapy

Kim, Ryul, Hong, Jung Yong, Lee, Jeeyun, Kwon, Ghee Young, Jeong, Byong Chang, Park, Se Hoon · 2021 · Cancer Research and Treatment · DOI

Full title: Genomic Sequencing for Bladder Urothelial Carcinoma and Its Clinical Implications for Immunotherapy

Authors: Kim, Ryul, Hong, Jung Yong, Lee, Jeeyun, Kwon, Ghee Young, Jeong, Byong Chang, Park, Se Hoon

Year: 2021

Venue: Cancer Research and Treatment

DOI: https://doi.org/10.4143/crt.2021.854

Paper CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption.

Harper, Justin, Gordon, Shari, Chan, Chi Ngai, Wang, Hong, Lindemuth, Emily, Galardi, Cristin, Falcinelli, Shane D, Raines, Samuel L M, Read, Jenna L, Nguyen, Kevin, McGary, Colleen S, Nekorchuk, Michael, Busman-Sahay, Kathleen, Schawalder, James, King, Colin, Pino, Maria, Micci, Luca, Cervasi, Barbara, Jean, Sherrie, Sanderson, Andrew, Johns, Brian, Koblansky, A Alicia, Amrine-Madsen, Heather, Lifson, Jeffrey, Margolis, David M, Silvestri, Guido, Bar, Katharine J, Favre, David, Estes, Jacob D, Paiardini, Mirko · 2020 · Nature medicine · DOI

Full title: CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption.

Authors: Harper, Justin, Gordon, Shari, Chan, Chi Ngai, Wang, Hong, Lindemuth, Emily, Galardi, Cristin, Falcinelli, Shane D, Raines, Samuel L M, Read, Jenna L, Nguyen, Kevin, McGary, Colleen S, Nekorchuk, Michael, Busman-Sahay, Kathleen, Schawalder, James, King, Colin, Pino, Maria, Micci, Luca, Cervasi, Barbara, Jean, Sherrie, Sanderson, Andrew, Johns, Brian, Koblansky, A Alicia, Amrine-Madsen, Heather, Lifson, Jeffrey, Margolis, David M, Silvestri, Guido, Bar, Katharine J, Favre, David, Estes, Jacob D, Paiardini, Mirko

Year: 2020

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-020-0782-y

Paper Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials?

Simmet, V, Eberst, L, Marabelle, A, Cassier, P A · 2019 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials?

Authors: Simmet, V, Eberst, L, Marabelle, A, Cassier, P A

Year: 2019

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdz286

Paper CTIM-28. INTRACRANIAL AND SYSTEMIC EFFICACY OF DUAL IMMUNE CHECKPOINT BLOCKADE (NIVOLUMAB AND IPILIMUMAB) IN MELANOMA BRAIN METASTASES: A META-ANALYSIS

Sarfraz, Zouina, Ganiyani, Mohammad Arfat, Mustafayev, Fatma Nihan Akkoç, Qidwai, Khalid, Odia, Yazmín, Kotecha, Rupesh, Mansouri, Alireza, Ahluwalia, Manmeet S. · 2025 · Neuro-Oncology · DOI

Full title: CTIM-28. INTRACRANIAL AND SYSTEMIC EFFICACY OF DUAL IMMUNE CHECKPOINT BLOCKADE (NIVOLUMAB AND IPILIMUMAB) IN MELANOMA BRAIN METASTASES: A META-ANALYSIS

Authors: Sarfraz, Zouina, Ganiyani, Mohammad Arfat, Mustafayev, Fatma Nihan Akkoç, Qidwai, Khalid, Odia, Yazmín, Kotecha, Rupesh, Mansouri, Alireza, Ahluwalia, Manmeet S.

Year: 2025

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noaf201.0485

Paper Cancer immunotherapy with check point inhibitor can cause autoimmune adverse events due to loss of Treg homeostasis.

Kumar, Prabhakaran, Saini, Shikha, Prabhakar, Bellur S · 2020 · Seminars in cancer biology · DOI

Full title: Cancer immunotherapy with check point inhibitor can cause autoimmune adverse events due to loss of Treg homeostasis.

Authors: Kumar, Prabhakaran, Saini, Shikha, Prabhakar, Bellur S

Year: 2020

Venue: Seminars in cancer biology

DOI: https://doi.org/10.1016/j.semcancer.2019.01.006

Paper Tumor mutation burden in the prognosis and response of lung cancer patients to immune-checkpoint inhibition therapies.

Vryza, Paraskevi, Fischer, Timo, Mistakidi, Elena, Zaravinos, Apostolos · 2023 · Translational oncology · DOI

Full title: Tumor mutation burden in the prognosis and response of lung cancer patients to immune-checkpoint inhibition therapies.

Authors: Vryza, Paraskevi, Fischer, Timo, Mistakidi, Elena, Zaravinos, Apostolos

Year: 2023

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2023.101788

Paper Erythema nodosum-like panniculitis mimicking disease recurrence: A novel toxicity from immune checkpoint blockade therapy-Report of 2 patients.

Tetzlaff, Michael T, Jazaeri, Amir A, Torres-Cabala, Carlos A, Korivi, Brinda R, Landon, Genie A, Nagarajan, Priyadharsini, Choksi, Adrienne, Chen, Leon, Uemura, Marc, Aung, Phyu P, Diab, Adi, Sharma, Padmanee, Davies, Michael A, Amaria, Rodabe, Prieto, Victor G, Curry, Jonathan L · 2017 · Journal of cutaneous pathology · DOI

Full title: Erythema nodosum-like panniculitis mimicking disease recurrence: A novel toxicity from immune checkpoint blockade therapy-Report of 2 patients.

Authors: Tetzlaff, Michael T, Jazaeri, Amir A, Torres-Cabala, Carlos A, Korivi, Brinda R, Landon, Genie A, Nagarajan, Priyadharsini, Choksi, Adrienne, Chen, Leon, Uemura, Marc, Aung, Phyu P, Diab, Adi, Sharma, Padmanee, Davies, Michael A, Amaria, Rodabe, Prieto, Victor G, Curry, Jonathan L

Year: 2017

Venue: Journal of cutaneous pathology

DOI: https://doi.org/10.1111/cup.13044

Paper Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.

Duperret, Elizabeth K, Wise, Megan C, Trautz, Aspen, Villarreal, Daniel O, Ferraro, Bernadette, Walters, Jewell, Yan, Jian, Khan, Amir, Masteller, Emma, Humeau, Laurent, Weiner, David B · 2018 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.

Authors: Duperret, Elizabeth K, Wise, Megan C, Trautz, Aspen, Villarreal, Daniel O, Ferraro, Bernadette, Walters, Jewell, Yan, Jian, Khan, Amir, Masteller, Emma, Humeau, Laurent, Weiner, David B

Year: 2018

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1016/j.ymthe.2017.11.010

Paper The Role of BRAF-Targeted Therapy for Advanced Melanoma in the Immunotherapy Era.

Vanella, Vito, Festino, Lucia, Trojaniello, Claudia, Vitale, Maria Grazia, Sorrentino, Antonio, Paone, Miriam, Ascierto, Paolo A · 2019 · Current oncology reports · DOI

Full title: The Role of BRAF-Targeted Therapy for Advanced Melanoma in the Immunotherapy Era.

Authors: Vanella, Vito, Festino, Lucia, Trojaniello, Claudia, Vitale, Maria Grazia, Sorrentino, Antonio, Paone, Miriam, Ascierto, Paolo A

Year: 2019

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-019-0827-x

Paper Anti-PD-1/PD-L1 immunotherapy in conversion treatment of locally advanced hepatocellular carcinoma.

Chen, Jiaqi, Zhang, Ding, Yuan, Ying · 2023 · Clinical and experimental medicine · DOI

Full title: Anti-PD-1/PD-L1 immunotherapy in conversion treatment of locally advanced hepatocellular carcinoma.

Authors: Chen, Jiaqi, Zhang, Ding, Yuan, Ying

Year: 2023

Venue: Clinical and experimental medicine

DOI: https://doi.org/10.1007/s10238-022-00873-6

Paper Management of side effects of immune checkpoint blockade by anti-CTLA-4 and anti-PD-1 antibodies in metastatic melanoma.

Kähler, Katharina C, Hassel, Jessica C, Heinzerling, Lucie, Loquai, Carmen, Mössner, Rotraut, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf, “Cutaneous Side Effects” Committee of the Work Group Dermatological Oncology (ADO) · 2016 · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · DOI

Full title: Management of side effects of immune checkpoint blockade by anti-CTLA-4 and anti-PD-1 antibodies in metastatic melanoma.

Authors: Kähler, Katharina C, Hassel, Jessica C, Heinzerling, Lucie, Loquai, Carmen, Mössner, Rotraut, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf, “Cutaneous Side Effects” Committee of the Work Group Dermatological Oncology (ADO)

Year: 2016

Venue: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

DOI: https://doi.org/10.1111/ddg.13047

Paper Abstract 2858: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity

Rech, Andrew J., Victor, Christina Twyman-Saint, Maity, Amit, Rengan, Ramesh, Pauken, Kristen E., Stelekati, Erietta, Benci, Joseph L., Xu, Bihui, Dada, Hannah, Odorizzi, Pamela M., Herati, Ramin S., Mansfield, Kathleen D., Patsch, Dana, Amaravadi, Ravi K., Schuchter, Lynn M., Ishwaran, Hemant, Mick, Rosemarie, Pryma, Daniel A., Xu, Xiaowei, Feldman, Michael D., Gangadhar, Tara C., Hahn, Stephen M., Wherry, E. John, Minn, Andy J., Vonderheide, Robert H. · 2015 · Cancer Research · DOI

Full title: Abstract 2858: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity

Authors: Rech, Andrew J., Victor, Christina Twyman-Saint, Maity, Amit, Rengan, Ramesh, Pauken, Kristen E., Stelekati, Erietta, Benci, Joseph L., Xu, Bihui, Dada, Hannah, Odorizzi, Pamela M., Herati, Ramin S., Mansfield, Kathleen D., Patsch, Dana, Amaravadi, Ravi K., Schuchter, Lynn M., Ishwaran, Hemant, Mick, Rosemarie, Pryma, Daniel A., Xu, Xiaowei, Feldman, Michael D., Gangadhar, Tara C., Hahn, Stephen M., Wherry, E. John, Minn, Andy J., Vonderheide, Robert H.

Year: 2015

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2015-2858

Paper Mismatch repair deficiency associated with complete remission to combination programmed cell death ligand immune therapy in a patient with sporadic urothelial carcinoma: immunotheranostic considerations

M. Castro, N. Goldstein · 2015 · Journal of Immunotherapy for Cancer · DOI

Full title: Mismatch repair deficiency associated with complete remission to combination programmed cell death ligand immune therapy in a patient with sporadic urothelial carcinoma: immunotheranostic considerations

Authors: M. Castro, N. Goldstein

Year: 2015

Venue: Journal of Immunotherapy for Cancer

DOI: https://doi.org/10.1186/s40425-015-0104-y

Paper Future directions in Hodgkin lymphoma: checkpoint inhibitors and beyond.

Desai, Sanjal, Ansell, Stephen M · 2021 · Leukemia & lymphoma · DOI

Full title: Future directions in Hodgkin lymphoma: checkpoint inhibitors and beyond.

Authors: Desai, Sanjal, Ansell, Stephen M

Year: 2021

Venue: Leukemia & lymphoma

DOI: https://doi.org/10.1080/10428194.2021.1885667

Paper Management of metastatic melanoma with combinations including PD-1 inhibitors.

Maul, Lara Valeska, Ramelyte, Egle, Dummer, Reinhard, Mangana, Joanna · 2025 · Expert opinion on biological therapy · DOI

Full title: Management of metastatic melanoma with combinations including PD-1 inhibitors.

Authors: Maul, Lara Valeska, Ramelyte, Egle, Dummer, Reinhard, Mangana, Joanna

Year: 2025

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2025.2485315

Paper Retrospective study of the combination of TP and PF regimens with or without immune checkpoint inhibitors for the first-line treatment of locally advanced or advanced esophageal squamous cell carcinoma

Zhang, Zhengfeng, Yang, Lei, Wang, Dazhen, Ruan, Yuli, Zhang, Jianji, Zhao, Lu, Liu, Yang, Lou, Changjie · 2023 · Therapeutic Advances in Medical Oncology · DOI

Full title: Retrospective study of the combination of TP and PF regimens with or without immune checkpoint inhibitors for the first-line treatment of locally advanced or advanced esophageal squamous cell carcinoma

Authors: Zhang, Zhengfeng, Yang, Lei, Wang, Dazhen, Ruan, Yuli, Zhang, Jianji, Zhao, Lu, Liu, Yang, Lou, Changjie

Year: 2023

Venue: Therapeutic Advances in Medical Oncology

DOI: https://doi.org/10.1177/17588359231169981

Paper Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti–PD-1 Therapy

Chida, Keigo, Kawazoe, Akihito, Suzuki, Toshihiro, Kawazu, Masahito, Ueno, Toshihide, Takenouchi, Kazumasa, Nakamura, Yoshiaki, Kuboki, Yasutoshi, Kotani, Daisuke, Kojima, Takashi, Bando, Hideaki, Mishima, Saori, Kuwata, Takeshi, Sakamoto, Naoya, Watanabe, Jun, Mano, Hiroyuki, Ikeda, Masafumi, Shitara, Kohei, Endo, Itaru, Nakatsura, Tetsuya, Yoshino, Takayuki · 2022 · Clinical Cancer Research · DOI

Full title: Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti–PD-1 Therapy

Authors: Chida, Keigo, Kawazoe, Akihito, Suzuki, Toshihiro, Kawazu, Masahito, Ueno, Toshihide, Takenouchi, Kazumasa, Nakamura, Yoshiaki, Kuboki, Yasutoshi, Kotani, Daisuke, Kojima, Takashi, Bando, Hideaki, Mishima, Saori, Kuwata, Takeshi, Sakamoto, Naoya, Watanabe, Jun, Mano, Hiroyuki, Ikeda, Masafumi, Shitara, Kohei, Endo, Itaru, Nakatsura, Tetsuya, Yoshino, Takayuki

Year: 2022

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-22-0041

Paper Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors.

Weinmann, Sophia C, Pisetsky, David S · 2019 · Rheumatology (Oxford, England) · DOI

Full title: Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors.

Authors: Weinmann, Sophia C, Pisetsky, David S

Year: 2019

Venue: Rheumatology (Oxford, England)

DOI: https://doi.org/10.1093/rheumatology/kez308

Paper - **Journal:** Russian Journal of Cardiology - **Source:** semanticscholar - **Content Type:** Metadata only

A. Gvozdeva, S. A. Yakovlev, S. A. Bliznuyk, A. Komarova, Z. A. Bagatelya · 2025 · Russian Journal of Cardiology · DOI

Full title: - **Journal:** Russian Journal of Cardiology - **Source:** semanticscholar - **Content Type:** Metadata only

Authors: A. Gvozdeva, S. A. Yakovlev, S. A. Bliznuyk, A. Komarova, Z. A. Bagatelya

Year: 2025

Venue: Russian Journal of Cardiology

DOI: https://doi.org/10.15829/1560-4071-2025-6479

Paper The predictive value of PD-L1 expression in patients with advanced hepatocellular carcinoma treated with PD-1/PD-L1 inhibitors: A systematic review and meta-analysis.

Yang, Yao, Chen, Dongbo, Zhao, Bigeng, Ren, Liying, Huang, Rui, Feng, Bo, Chen, Hongsong · 2023 · Cancer medicine · DOI

Full title: The predictive value of PD-L1 expression in patients with advanced hepatocellular carcinoma treated with PD-1/PD-L1 inhibitors: A systematic review and meta-analysis.

Authors: Yang, Yao, Chen, Dongbo, Zhao, Bigeng, Ren, Liying, Huang, Rui, Feng, Bo, Chen, Hongsong

Year: 2023

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.5676

Paper The present status and future prospects of peptide-based cancer vaccines.

M. Hirayama, Y. Nishimura · 2016 · International Immunology · DOI

Full title: The present status and future prospects of peptide-based cancer vaccines.

Authors: M. Hirayama, Y. Nishimura

Year: 2016

Venue: International Immunology

DOI: https://doi.org/10.1093/intimm/dxw027

Paper Melanoma: Pathogenesis and Targeted Therapy.

Fu, Yang, Liu, Jie, Mo, Zeming, Wang, Bin, Deng, Yaotiao, Jiang, Yu · 2026 · MedComm · DOI

Full title: Melanoma: Pathogenesis and Targeted Therapy.

Authors: Fu, Yang, Liu, Jie, Mo, Zeming, Wang, Bin, Deng, Yaotiao, Jiang, Yu

Year: 2026

Venue: MedComm

DOI: https://doi.org/10.1002/mco2.70566

Paper The Potential Applicability of Single-Domain Antibodies (VHH): From Checkpoint Blockade to Infectious Disease Therapy

Kozani, Pouya Safarzadeh, Kozani, Pooria Safarzadeh, Rahbarizadeh, Fatemeh · 2021 · Trends in Medical Sciences · DOI

Full title: The Potential Applicability of Single-Domain Antibodies (VHH): From Checkpoint Blockade to Infectious Disease Therapy

Authors: Kozani, Pouya Safarzadeh, Kozani, Pooria Safarzadeh, Rahbarizadeh, Fatemeh

Year: 2021

Venue: Trends in Medical Sciences

DOI: https://doi.org/10.5812/tms.114888

Paper Benefits and risks of PD-1/PD-L1 inhibitors for recurrent small cell lung cancer: A systematic review and meta-analysis.

Zhou, Juyue, Du, Zhonghai, Liang, Yan, Zhang, Sensen · 2024 · Critical reviews in oncology/hematology · DOI

Full title: Benefits and risks of PD-1/PD-L1 inhibitors for recurrent small cell lung cancer: A systematic review and meta-analysis.

Authors: Zhou, Juyue, Du, Zhonghai, Liang, Yan, Zhang, Sensen

Year: 2024

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2023.104222

Paper Identification of human regulatory T cells in the setting of T-cell activation and anti-CTLA-4 immunotherapy on the basis of expression of latency-associated peptide.

Sun, Jingjing, Tang, Derek Ng, Fu, Tihui, Sharma, Padmanee · 2012 · Cancer discovery · DOI

Full title: Identification of human regulatory T cells in the setting of T-cell activation and anti-CTLA-4 immunotherapy on the basis of expression of latency-associated peptide.

Authors: Sun, Jingjing, Tang, Derek Ng, Fu, Tihui, Sharma, Padmanee

Year: 2012

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-11-0236

Paper RTHP-10. IMPACT OF COMBINATION IMMUNOTHERAPY WITH TUMOR TREATING FIELDS THERAPY IN A GLIOMA COHORT

Schulte, Jessica, Odia, Yazmín, Donovan, Laura, Iwamoto, Fábio M. · 2017 · Neuro-Oncology · DOI

Full title: RTHP-10. IMPACT OF COMBINATION IMMUNOTHERAPY WITH TUMOR TREATING FIELDS THERAPY IN A GLIOMA COHORT

Authors: Schulte, Jessica, Odia, Yazmín, Donovan, Laura, Iwamoto, Fábio M.

Year: 2017

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/nox168.895

Paper In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment.

Vanpouille-Box, Claire, Pilones, Karsten A, Wennerberg, Erik, Formenti, Silvia C, Demaria, Sandra · 2015 · Vaccine · DOI

Full title: In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment.

Authors: Vanpouille-Box, Claire, Pilones, Karsten A, Wennerberg, Erik, Formenti, Silvia C, Demaria, Sandra

Year: 2015

Venue: Vaccine

DOI: https://doi.org/10.1016/j.vaccine.2015.05.105

Paper The efficacy and safety of PD-1/PD-L1 inhibitors in patients with recurrent or metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis.

Wang, Bi-Cheng, Cao, Ru-Bo, Fu, Chen, Chen, Wang-Bing, Li, Pin-Dong, Lin, Guo-He, Qian, Xiao-Jun, Li, Yun-Tian, Liu, Quentin · 2020 · Oral oncology · DOI

Full title: The efficacy and safety of PD-1/PD-L1 inhibitors in patients with recurrent or metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis.

Authors: Wang, Bi-Cheng, Cao, Ru-Bo, Fu, Chen, Chen, Wang-Bing, Li, Pin-Dong, Lin, Guo-He, Qian, Xiao-Jun, Li, Yun-Tian, Liu, Quentin

Year: 2020

Venue: Oral oncology

DOI: https://doi.org/10.1016/j.oraloncology.2020.104640

Paper Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients: A meta-analysis of randomized controlled trials.

Yang, Wenwei, Li, Shuquan, Yang, Qingrui · 2019 · Medicine · DOI

Full title: Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients: A meta-analysis of randomized controlled trials.

Authors: Yang, Wenwei, Li, Shuquan, Yang, Qingrui

Year: 2019

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000015731

Paper Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Perez-Ruiz, Elisabeth, Minute, Luna, Otano, Itziar, Alvarez, Maite, Ochoa, Maria Carmen, Belsue, Virginia, de Andrea, Carlos, Rodriguez-Ruiz, Maria Esperanza, Perez-Gracia, Jose Luis, Marquez-Rodas, Ivan, Llacer, Casilda, Alvarez, Martina, de Luque, Vanesa, Molina, Carmen, Teijeira, Alvaro, Berraondo, Pedro, Melero, Ignacio · 2019 · Nature · DOI

Full title: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Authors: Perez-Ruiz, Elisabeth, Minute, Luna, Otano, Itziar, Alvarez, Maite, Ochoa, Maria Carmen, Belsue, Virginia, de Andrea, Carlos, Rodriguez-Ruiz, Maria Esperanza, Perez-Gracia, Jose Luis, Marquez-Rodas, Ivan, Llacer, Casilda, Alvarez, Martina, de Luque, Vanesa, Molina, Carmen, Teijeira, Alvaro, Berraondo, Pedro, Melero, Ignacio

Year: 2019

Venue: Nature

DOI: https://doi.org/10.1038/s41586-019-1162-y

Paper The current advances and future directions of PD-1/PD-L1 blockade in head and neck squamous cell carcinoma (HNSCC) in the era of immunotherapy.

Chen, Yunhao, Ding, Xingchen, Bai, Xinbin, Zhou, Zihan, Liu, Yu, Zhang, Xianbin, Yu, Jinming, Hu, Man · 2023 · International immunopharmacology · DOI

Full title: The current advances and future directions of PD-1/PD-L1 blockade in head and neck squamous cell carcinoma (HNSCC) in the era of immunotherapy.

Authors: Chen, Yunhao, Ding, Xingchen, Bai, Xinbin, Zhou, Zihan, Liu, Yu, Zhang, Xianbin, Yu, Jinming, Hu, Man

Year: 2023

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.110329

Paper 458 Antitumor mechanisms of local radiation and combination immunotherapy in an immunologically cold model of neuroblastoma

Aiken, Taylor, Voeller, Julie, Erbe, Amy K., Rakhmilevich, Alexander L., Sondel, Paul M. · 2020 · Regular and Young Investigator Award Abstracts · DOI

Full title: 458 Antitumor mechanisms of local radiation and combination immunotherapy in an immunologically cold model of neuroblastoma

Authors: Aiken, Taylor, Voeller, Julie, Erbe, Amy K., Rakhmilevich, Alexander L., Sondel, Paul M.

Year: 2020

Venue: Regular and Young Investigator Award Abstracts

DOI: https://doi.org/10.1136/jitc-2020-sitc2020.0458

Paper Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anticancer Immunity.

Leshem, Yasmin, O'Brien, James, Liu, Xiufen, Bera, Tapan K, Terabe, Masaki, Berzofsky, Jay A, Bossenmaier, Birgit, Niederfellner, Gerhard, Tai, Chin-Hsien, Reiter, Yoram, Pastan, Ira · 2017 · Cancer immunology research · DOI

Full title: Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anticancer Immunity.

Authors: Leshem, Yasmin, O'Brien, James, Liu, Xiufen, Bera, Tapan K, Terabe, Masaki, Berzofsky, Jay A, Bossenmaier, Birgit, Niederfellner, Gerhard, Tai, Chin-Hsien, Reiter, Yoram, Pastan, Ira

Year: 2017

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-16-0330

Paper Durable Responses in Patients With Advanced Cholangiocarcinoma on Sequential Dual-agent Immunotherapy After Progressing on Single-agent Immunotherapy.

Kaakour, Dalia, Hagopian, Garo, Lee, Sonia, Lee, Fa Chyi · 2022 · American journal of clinical oncology · DOI

Full title: Durable Responses in Patients With Advanced Cholangiocarcinoma on Sequential Dual-agent Immunotherapy After Progressing on Single-agent Immunotherapy.

Authors: Kaakour, Dalia, Hagopian, Garo, Lee, Sonia, Lee, Fa Chyi

Year: 2022

Venue: American journal of clinical oncology

DOI: https://doi.org/10.1097/COC.0000000000000941

Paper Artificial Transmembrane Oligopeptide-Integrated Interferon mRNA with Monoclonal Antibody to Improve Specificity and Efficacy of Cancer Immunotherapy.

Yan, Yinyu, Luo, Zijiang, Hu, Xinyuan, Ou, Meng, Huang, Mengsheng, Ni, Xu, Chen, Huan, Ding, Ya · 2025 · Advanced materials (Deerfield Beach, Fla.) · DOI

Full title: Artificial Transmembrane Oligopeptide-Integrated Interferon mRNA with Monoclonal Antibody to Improve Specificity and Efficacy of Cancer Immunotherapy.

Authors: Yan, Yinyu, Luo, Zijiang, Hu, Xinyuan, Ou, Meng, Huang, Mengsheng, Ni, Xu, Chen, Huan, Ding, Ya

Year: 2025

Venue: Advanced materials (Deerfield Beach, Fla.)

DOI: https://doi.org/10.1002/adma.202503139

Paper Spectrum and Clinical Activity of PD-1/PD-L1 Inhibitors: Regulatory Approval and Under Development.

Oliveira, Leandro Jonata Carvalho, Gongora, Aline Bobato Lara, Jardim, Denis Leonardo Fontes · 2020 · Current oncology reports · DOI

Full title: Spectrum and Clinical Activity of PD-1/PD-L1 Inhibitors: Regulatory Approval and Under Development.

Authors: Oliveira, Leandro Jonata Carvalho, Gongora, Aline Bobato Lara, Jardim, Denis Leonardo Fontes

Year: 2020

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-020-00928-5

Paper Resistance to PD-1/PD-L1 immune checkpoint blockade in advanced non-small cell lung cancer.

Li, Lijun, Pu, Haihong, Zhang, Xiaoxin, Guo, Xiaotian, Li, Guangrui, Zhang, Minghui · 2025 · Critical reviews in oncology/hematology · DOI

Full title: Resistance to PD-1/PD-L1 immune checkpoint blockade in advanced non-small cell lung cancer.

Authors: Li, Lijun, Pu, Haihong, Zhang, Xiaoxin, Guo, Xiaotian, Li, Guangrui, Zhang, Minghui

Year: 2025

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2025.104683

Paper EP1.01-55 Neoantigen Deletion Leads to Hyperprogressive Disease (HPD) in Non-Small Cell Lung Cancer (NSCLC) Treated with PD-1/PD-L1 Inhibitors

D. Wu, X. Hong, Yun-Bao Liu, Kaitai Zhang, Y. Hu, F. Gu, Zhongming Zhao, Jianfeng Liu, Lunxu Liu · 2019 · Journal of Thoracic Oncology · DOI

Full title: EP1.01-55 Neoantigen Deletion Leads to Hyperprogressive Disease (HPD) in Non-Small Cell Lung Cancer (NSCLC) Treated with PD-1/PD-L1 Inhibitors

Authors: D. Wu, X. Hong, Yun-Bao Liu, Kaitai Zhang, Y. Hu, F. Gu, Zhongming Zhao, Jianfeng Liu, Lunxu Liu

Year: 2019

Venue: Journal of Thoracic Oncology

DOI: https://doi.org/10.1016/j.jtho.2019.08.2030

Paper Combination checkpoint blockade for metastatic cutaneous malignancies in kidney transplant recipients.

Trager, Megan H, Coley, Shana M, Dube, Geoffrey, Khan, Shaheer, Ingham, Matthew, Samie, Faramarz H, Geskin, Larisa J, McDonnell, Diana, Brouder, Daniel, Saenger, Yvonne, Carvajal, Richard · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Combination checkpoint blockade for metastatic cutaneous malignancies in kidney transplant recipients.

Authors: Trager, Megan H, Coley, Shana M, Dube, Geoffrey, Khan, Shaheer, Ingham, Matthew, Samie, Faramarz H, Geskin, Larisa J, McDonnell, Diana, Brouder, Daniel, Saenger, Yvonne, Carvajal, Richard

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-000908

Paper Immune checkpoint inhibitor-induced hepatitis injury: risk factors, outcomes, and impact on survival.

Miah, Abdul, Tinoco, Gabriel, Zhao, Songzhu, Wei, Lai, Johns, Andrew, Patel, Sandip, Li, Mingjia, Grogan, Madison, Lopez, Gabrielle, Husain, Marium, Hoyd, Rebecca, Mumtaz, Khalid, Meara, Alexa, Bertino, Erin M, Kendra, Kari, Spakowicz, Daniel, Otterson, Gregory A, Presley, Carolyn J, Owen, Dwight H · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Immune checkpoint inhibitor-induced hepatitis injury: risk factors, outcomes, and impact on survival.

Authors: Miah, Abdul, Tinoco, Gabriel, Zhao, Songzhu, Wei, Lai, Johns, Andrew, Patel, Sandip, Li, Mingjia, Grogan, Madison, Lopez, Gabrielle, Husain, Marium, Hoyd, Rebecca, Mumtaz, Khalid, Meara, Alexa, Bertino, Erin M, Kendra, Kari, Spakowicz, Daniel, Otterson, Gregory A, Presley, Carolyn J, Owen, Dwight H

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-022-04340-3

Paper MP21-03 CD-70 BLOCKADE AS A NOVEL IMMUNOTHERAPY FOR THE TREATMENT OF CLEAR-CELL RENAL CELL CARCINOMA

Paras H Shah, M. Cepeda, Vidhu B. Joshi, S. Boorjian, B. Costello, J. Cheville, B. Leibovich · 2019 · Journal of Urology · DOI

Full title: MP21-03 CD-70 BLOCKADE AS A NOVEL IMMUNOTHERAPY FOR THE TREATMENT OF CLEAR-CELL RENAL CELL CARCINOMA

Authors: Paras H Shah, M. Cepeda, Vidhu B. Joshi, S. Boorjian, B. Costello, J. Cheville, B. Leibovich

Year: 2019

Venue: Journal of Urology

DOI: https://doi.org/10.1097/01.ju.0000555531.94998.87

Paper Salvage Surgery for Thoracic SMARCA4-Deficient Undifferentiated Tumor.

Kanayama, Masatoshi, Taira, Akihiro, Yoshimatsu, Katsuma, Matsumiya, Hiroki, Mori, Masataka, Takenaka, Masaru, Kuroda, Koji, Nawata, Aya, Tanaka, Fumihiro · 2025 · Annals of thoracic surgery short reports · DOI

Full title: Salvage Surgery for Thoracic SMARCA4-Deficient Undifferentiated Tumor.

Authors: Kanayama, Masatoshi, Taira, Akihiro, Yoshimatsu, Katsuma, Matsumiya, Hiroki, Mori, Masataka, Takenaka, Masaru, Kuroda, Koji, Nawata, Aya, Tanaka, Fumihiro

Year: 2025

Venue: Annals of thoracic surgery short reports

DOI: https://doi.org/10.1016/j.atssr.2024.08.008

Paper Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade.

Yu, Shuangjiang, Wang, Chao, Yu, Jicheng, Wang, Jinqiang, Lu, Yue, Zhang, Yuqi, Zhang, Xudong, Hu, Quanyin, Sun, Wujin, He, Chaoliang, Chen, Xuesi, Gu, Zhen · 2018 · Advanced materials (Deerfield Beach, Fla.) · DOI

Full title: Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade.

Authors: Yu, Shuangjiang, Wang, Chao, Yu, Jicheng, Wang, Jinqiang, Lu, Yue, Zhang, Yuqi, Zhang, Xudong, Hu, Quanyin, Sun, Wujin, He, Chaoliang, Chen, Xuesi, Gu, Zhen

Year: 2018

Venue: Advanced materials (Deerfield Beach, Fla.)

DOI: https://doi.org/10.1002/adma.201801527

Paper Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking.

Taggart, David, Andreou, Tereza, Scott, Karen J, Williams, Jennifer, Rippaus, Nora, Brownlie, Rebecca J, Ilett, Elizabeth J, Salmond, Robert J, Melcher, Alan, Lorger, Mihaela · 2018 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking.

Authors: Taggart, David, Andreou, Tereza, Scott, Karen J, Williams, Jennifer, Rippaus, Nora, Brownlie, Rebecca J, Ilett, Elizabeth J, Salmond, Robert J, Melcher, Alan, Lorger, Mihaela

Year: 2018

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1714089115

Paper Combination immunotherapy of oncolytic virus nanovesicles and PD-1 blockade effectively enhances therapeutic effects and boosts antitumour immune response.

Ji, Wei, Li, Lanfang, Zhou, Shiyong, Qiu, Lihua, Qian, Zhengzi, Zhang, Huilai, Zhao, Peiqi · 2020 · Journal of drug targeting · DOI

Full title: Combination immunotherapy of oncolytic virus nanovesicles and PD-1 blockade effectively enhances therapeutic effects and boosts antitumour immune response.

Authors: Ji, Wei, Li, Lanfang, Zhou, Shiyong, Qiu, Lihua, Qian, Zhengzi, Zhang, Huilai, Zhao, Peiqi

Year: 2020

Venue: Journal of drug targeting

DOI: https://doi.org/10.1080/1061186X.2020.1766473

Paper Next-generation CTLA-4 targeting molecules and combination therapy: promising strategies for improving cancer immunotherapy.

Rudqvist, Nils-Petter, Avagyan, Manushak, Chand, Dhan · 2023 · Oncoimmunology · DOI

Full title: Next-generation CTLA-4 targeting molecules and combination therapy: promising strategies for improving cancer immunotherapy.

Authors: Rudqvist, Nils-Petter, Avagyan, Manushak, Chand, Dhan

Year: 2023

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2023.2275333

Paper Patient and treatment characteristics of emergency presentations due to immune-mediated toxicities.

S. Nahm, R. Heywood, S. Callaghan, P. Serra-Bellver, Avinash Gupta, T. Cooksley, P. Lorigan · 2021 · European Journal of Cancer · DOI

Full title: Patient and treatment characteristics of emergency presentations due to immune-mediated toxicities.

Authors: S. Nahm, R. Heywood, S. Callaghan, P. Serra-Bellver, Avinash Gupta, T. Cooksley, P. Lorigan

Year: 2021

Venue: European Journal of Cancer

DOI: https://doi.org/10.1200/jco.2021.39.15_suppl.6586

Paper Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.

Ochoa, Maria Carmen, Sanchez-Gregorio, Sandra, de Andrea, Carlos E, Garasa, Saray, Alvarez, Maite, Olivera, Irene, Glez-Vaz, Javier, Luri-Rey, Carlos, Etxeberria, Iñaki, Cirella, Assunta, Azpilikueta, Arantza, Berraondo, Pedro, Argemi, Josepmaria, Sangro, Bruno, Teijeira, Alvaro, Melero, Ignacio · 2023 · Cell reports. Medicine · DOI

Full title: Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.

Authors: Ochoa, Maria Carmen, Sanchez-Gregorio, Sandra, de Andrea, Carlos E, Garasa, Saray, Alvarez, Maite, Olivera, Irene, Glez-Vaz, Javier, Luri-Rey, Carlos, Etxeberria, Iñaki, Cirella, Assunta, Azpilikueta, Arantza, Berraondo, Pedro, Argemi, Josepmaria, Sangro, Bruno, Teijeira, Alvaro, Melero, Ignacio

Year: 2023

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2023.101009

Paper Current and emerging options for patients with melanoma brain metastases.

Kreidieh, Firas Y, Tawbi, Hussein A · 2022 · Clinical advances in hematology & oncology : H&O

Full title: Current and emerging options for patients with melanoma brain metastases.

Authors: Kreidieh, Firas Y, Tawbi, Hussein A

Year: 2022

Venue: Clinical advances in hematology & oncology : H&O

Paper Combinatorial Therapies in Melanoma: MAPK Inhibitors and Beyond.

Zhou, Alice Y, Johnson, Douglas B · 2018 · American journal of clinical dermatology · DOI

Full title: Combinatorial Therapies in Melanoma: MAPK Inhibitors and Beyond.

Authors: Zhou, Alice Y, Johnson, Douglas B

Year: 2018

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-017-0320-y

Paper What Is on the Horizon for Novel Immunotherapies in Lung Cancer?

Garon, Edward B, Li, Debory Yi · 2020 · Cancer journal (Sudbury, Mass.) · DOI

Full title: What Is on the Horizon for Novel Immunotherapies in Lung Cancer?

Authors: Garon, Edward B, Li, Debory Yi

Year: 2020

Venue: Cancer journal (Sudbury, Mass.)

DOI: https://doi.org/10.1097/PPO.0000000000000486

Paper The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.

Kvarnhammar, Anne Månsson, Veitonmäki, Niina, Hägerbrand, Karin, Dahlman, Anna, Smith, Karin Enell, Fritzell, Sara, von Schantz, Laura, Thagesson, Mia, Werchau, Doreen, Smedenfors, Kristine, Johansson, Maria, Rosén, Anna, Åberg, Ida, Winnerstam, Magnus, Nyblom, Eva, Barchan, Karin, Furebring, Christina, Norlén, Per, Ellmark, Peter · 2019 · Journal for immunotherapy of cancer · DOI

Full title: The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.

Authors: Kvarnhammar, Anne Månsson, Veitonmäki, Niina, Hägerbrand, Karin, Dahlman, Anna, Smith, Karin Enell, Fritzell, Sara, von Schantz, Laura, Thagesson, Mia, Werchau, Doreen, Smedenfors, Kristine, Johansson, Maria, Rosén, Anna, Åberg, Ida, Winnerstam, Magnus, Nyblom, Eva, Barchan, Karin, Furebring, Christina, Norlén, Per, Ellmark, Peter

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0570-8

Paper Combination immunotherapy with GM-CSF and CTLA-4 blockade for hormone refractory prostate cancer: Balancing the expansion of activated effector and regulatory T cells

Fong, Lawrence, Kavanagh, Brian D., Hou, Yayi, O’Brien, Shaun, Carrasco‐Valiente, Julia, Weinberg, Vivian, Rini, Brian I., Small, Eric J. · 2007 · Journal of Clinical Oncology · DOI

Full title: Combination immunotherapy with GM-CSF and CTLA-4 blockade for hormone refractory prostate cancer: Balancing the expansion of activated effector and regulatory T cells

Authors: Fong, Lawrence, Kavanagh, Brian D., Hou, Yayi, O’Brien, Shaun, Carrasco‐Valiente, Julia, Weinberg, Vivian, Rini, Brian I., Small, Eric J.

Year: 2007

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2007.25.18_suppl.3001

Paper Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors.

Derer, Anja, Frey, Benjamin, Fietkau, Rainer, Gaipl, Udo S · 2016 · Cancer immunology, immunotherapy : CII · DOI

Full title: Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors.

Authors: Derer, Anja, Frey, Benjamin, Fietkau, Rainer, Gaipl, Udo S

Year: 2016

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-015-1771-8

Paper NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade.

Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Joseph L, Nabatiyan, Arman, Ruby, Carl E, Snook, Joshua D, Rudra, Jai S, Schenkel, Jason M, Masopust, David, Zloza, Andrew, Kaufman, Howard L · 2015 · Journal for immunotherapy of cancer · DOI

Full title: NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade.

Authors: Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Joseph L, Nabatiyan, Arman, Ruby, Carl E, Snook, Joshua D, Rudra, Jai S, Schenkel, Jason M, Masopust, David, Zloza, Andrew, Kaufman, Howard L

Year: 2015

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-015-0063-3

Paper Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies.

Verbrugge, Inge, Galli, Mara, Smyth, Mark J, Johnstone, Ricky W, Haynes, Nicole M · 2012 · Oncoimmunology · DOI

Full title: Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies.

Authors: Verbrugge, Inge, Galli, Mara, Smyth, Mark J, Johnstone, Ricky W, Haynes, Nicole M

Year: 2012

Venue: Oncoimmunology

DOI: https://doi.org/10.4161/onci.21652

Paper Data from Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade

Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, He, Shan, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane D., Li, Meng, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L. · 2025 · DOI

Full title: Data from Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade

Authors: Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, He, Shan, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane D., Li, Meng, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L.

Year: 2025

DOI: https://doi.org/10.1158/2159-8290.c.7963870

Paper Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Peggs, Karl S., Quezada, Sergio A., Chambers, Cynthia A., Korman, Alan J., Allison, James P. · 2009 · The Journal of Experimental Medicine · DOI

Full title: Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Authors: Peggs, Karl S., Quezada, Sergio A., Chambers, Cynthia A., Korman, Alan J., Allison, James P.

Year: 2009

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20082492

Paper Reviewer #3 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

J., Mullen Nicholas, K., Shukla Surendra, Ravi, Thakur, Sundeep, Kollala Sai, Wang, Dezhen, Nina, Chaika, A., LaBreck Drew, Reddy, Mallareddy Jayapal, H., Price David, Amarnath, Natarajan, Kamiya, Mehla, B., Sykes David, A., Hollingsworth Michael, K., Singh Pankaj · 2023 · DOI

Full title: Reviewer #3 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: J., Mullen Nicholas, K., Shukla Surendra, Ravi, Thakur, Sundeep, Kollala Sai, Wang, Dezhen, Nina, Chaika, A., LaBreck Drew, Reddy, Mallareddy Jayapal, H., Price David, Amarnath, Natarajan, Kamiya, Mehla, B., Sykes David, A., Hollingsworth Michael, K., Singh Pankaj

Year: 2023

DOI: https://doi.org/10.7554/elife.87292.1.sa0

Paper PD-L1 and IDO expression in cervical and vulvar invasive and intraepithelial squamous neoplasias: implications for combination immunotherapy.

Chinn, Zachary, Stoler, Mark H, Mills, Anne M · 2019 · Histopathology · DOI

Full title: PD-L1 and IDO expression in cervical and vulvar invasive and intraepithelial squamous neoplasias: implications for combination immunotherapy.

Authors: Chinn, Zachary, Stoler, Mark H, Mills, Anne M

Year: 2019

Venue: Histopathology

DOI: https://doi.org/10.1111/his.13723

Paper Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.

Müller, Philipp, Kreuzaler, Matthias, Khan, Tarik, Thommen, Daniela S, Martin, Kea, Glatz, Katharina, Savic, Spasenija, Harbeck, Nadia, Nitz, Ulrike, Gluz, Oleg, von Bergwelt-Baildon, Michael, Kreipe, Hans, Reddy, Sai, Christgen, Matthias, Zippelius, Alfred · 2015 · Science translational medicine · DOI

Full title: Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.

Authors: Müller, Philipp, Kreuzaler, Matthias, Khan, Tarik, Thommen, Daniela S, Martin, Kea, Glatz, Katharina, Savic, Spasenija, Harbeck, Nadia, Nitz, Ulrike, Gluz, Oleg, von Bergwelt-Baildon, Michael, Kreipe, Hans, Reddy, Sai, Christgen, Matthias, Zippelius, Alfred

Year: 2015

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.aac4925

Paper Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer.

McCall, Neal S, Dicker, Adam P, Lu, Bo · 2018 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer.

Authors: McCall, Neal S, Dicker, Adam P, Lu, Bo

Year: 2018

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-17-3269

Paper Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou · 2023 · DOI

Full title: Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Authors: Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou

Year: 2023

DOI: https://doi.org/10.1158/0008-5472.c.6711188.v1

Paper Head and neck squamous cell carcinoma

Johnson, Daniel E., Burtness, Barbara, Leemans, C. René, Lui, Vivian Wai Yan, Bauman, Julie E., Grandis, Jennifer R. · 2020 · Nature Reviews Disease Primers · DOI

Full title: Head and neck squamous cell carcinoma

Authors: Johnson, Daniel E., Burtness, Barbara, Leemans, C. René, Lui, Vivian Wai Yan, Bauman, Julie E., Grandis, Jennifer R.

Year: 2020

Venue: Nature Reviews Disease Primers

DOI: https://doi.org/10.1038/s41572-020-00224-3

Paper Update on Programmed Death-1 and Programmed Death-Ligand 1 Inhibition in the Treatment of Advanced or Metastatic Non-Small Cell Lung Cancer.

Iafolla, Marco A J, Juergens, Rosalyn A · 2017 · Frontiers in oncology · DOI

Full title: Update on Programmed Death-1 and Programmed Death-Ligand 1 Inhibition in the Treatment of Advanced or Metastatic Non-Small Cell Lung Cancer.

Authors: Iafolla, Marco A J, Juergens, Rosalyn A

Year: 2017

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2017.00067

Paper Tumor mutational burden (TMB) and response rates to immune checkpoint inhibitors (ICIs) targeting PD-1, CTLA-4, and combination.

A. Osipov, A. Popovic, Alexander C. Hopkins, G. Frampton, L. Albacker, N. Azad, D. Laheru, Lei Zheng, E. Jaffee, M. Yarchoan · 2019 · Journal of Clinical Oncology · DOI

Full title: Tumor mutational burden (TMB) and response rates to immune checkpoint inhibitors (ICIs) targeting PD-1, CTLA-4, and combination.

Authors: A. Osipov, A. Popovic, Alexander C. Hopkins, G. Frampton, L. Albacker, N. Azad, D. Laheru, Lei Zheng, E. Jaffee, M. Yarchoan

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.2578

Paper Targeting regulatory T cells in tumor immunotherapy

Smyth, Mark J., Ngiow, Shin Foong, Teng, Michele W.L. · 2014 · Immunology and Cell Biology · DOI

Full title: Targeting regulatory T cells in tumor immunotherapy

Authors: Smyth, Mark J., Ngiow, Shin Foong, Teng, Michele W.L.

Year: 2014

Venue: Immunology and Cell Biology

DOI: https://doi.org/10.1038/icb.2014.33

Paper Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery.

Qian, Jack M, Yu, James B, Kluger, Harriet M, Chiang, Veronica L S · 2016 · Cancer · DOI

Full title: Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery.

Authors: Qian, Jack M, Yu, James B, Kluger, Harriet M, Chiang, Veronica L S

Year: 2016

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.30138

Paper Treatment-related adverse events of PD-1/PD-L1 inhibitors combined with CTLA-4 inhibitors in clinical trials: a meta-analysis.

Mi, Ze, Zhang, Yunshu, Feng, Zhichao, Liu, Jiahao, Wu, Jianmin, Tan, Hongpei, Ma, Xiaoqian, Liu, Zhenguo, Rong, Pengfei · 2022 · Artificial cells, nanomedicine, and biotechnology · DOI

Full title: Treatment-related adverse events of PD-1/PD-L1 inhibitors combined with CTLA-4 inhibitors in clinical trials: a meta-analysis.

Authors: Mi, Ze, Zhang, Yunshu, Feng, Zhichao, Liu, Jiahao, Wu, Jianmin, Tan, Hongpei, Ma, Xiaoqian, Liu, Zhenguo, Rong, Pengfei

Year: 2022

Venue: Artificial cells, nanomedicine, and biotechnology

DOI: https://doi.org/10.1080/21691401.2022.2131354

Paper Inhibition of SRC family kinases facilitates anti-CTLA4 immunotherapy in head and neck squamous cell carcinoma.

Yu, Guang-Tao, Mao, Liang, Wu, Lei, Deng, Wei-Wei, Bu, Lin-Lin, Liu, Jian-Feng, Chen, Lei, Yang, Lei-Lei, Wu, Hao, Zhang, Wen-Feng, Sun, Zhi-Jun · 2018 · Cellular and molecular life sciences : CMLS · DOI

Full title: Inhibition of SRC family kinases facilitates anti-CTLA4 immunotherapy in head and neck squamous cell carcinoma.

Authors: Yu, Guang-Tao, Mao, Liang, Wu, Lei, Deng, Wei-Wei, Bu, Lin-Lin, Liu, Jian-Feng, Chen, Lei, Yang, Lei-Lei, Wu, Hao, Zhang, Wen-Feng, Sun, Zhi-Jun

Year: 2018

Venue: Cellular and molecular life sciences : CMLS

DOI: https://doi.org/10.1007/s00018-018-2863-3

Paper Analysis of immune-related adverse events in gastrointestinal malignancy patients treated with immune checkpoint inhibitors.

Niu, Chengu, Zhu, Kaiwen, Zhang, Jing, Joshi, Utsav, Liu, Hongli, Zahid, Salman, Jadhav, Nagesh, Okolo, Patrick I · 2024 · International journal of cancer · DOI

Full title: Analysis of immune-related adverse events in gastrointestinal malignancy patients treated with immune checkpoint inhibitors.

Authors: Niu, Chengu, Zhu, Kaiwen, Zhang, Jing, Joshi, Utsav, Liu, Hongli, Zahid, Salman, Jadhav, Nagesh, Okolo, Patrick I

Year: 2024

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.34813

Paper Microtubule-depolymerizing agents used in antibody-drug conjugates induce antitumor immunity by stimulation of dendritic cells.

Müller, Philipp, Martin, Kea, Theurich, Sebastian, Schreiner, Jens, Savic, Spasenija, Terszowski, Grzegorz, Lardinois, Didier, Heinzelmann-Schwarz, Viola A, Schlaak, Max, Kvasnicka, Hans-Michael, Spagnoli, Giulio, Dirnhofer, Stephan, Speiser, Daniel E, von Bergwelt-Baildon, Michael, Zippelius, Alfred · 2014 · Cancer immunology research · DOI

Full title: Microtubule-depolymerizing agents used in antibody-drug conjugates induce antitumor immunity by stimulation of dendritic cells.

Authors: Müller, Philipp, Martin, Kea, Theurich, Sebastian, Schreiner, Jens, Savic, Spasenija, Terszowski, Grzegorz, Lardinois, Didier, Heinzelmann-Schwarz, Viola A, Schlaak, Max, Kvasnicka, Hans-Michael, Spagnoli, Giulio, Dirnhofer, Stephan, Speiser, Daniel E, von Bergwelt-Baildon, Michael, Zippelius, Alfred

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0198

Paper Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape.

L. Emens, P. Ascierto, P. Darcy, S. Demaria, A. Eggermont, William L. Redmond, B. Seliger, F. Marincola · 2017 · European Journal of Cancer · DOI

Full title: Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape.

Authors: L. Emens, P. Ascierto, P. Darcy, S. Demaria, A. Eggermont, William L. Redmond, B. Seliger, F. Marincola

Year: 2017

Venue: European Journal of Cancer

DOI: https://doi.org/10.1016/j.ejca.2017.01.035

Paper Physical- and Chemical-Dually ROS-Responsive Nano-in-Gel Platforms with Sequential Release of OX40 Agonist and PD-1 Inhibitor for Augmented Combination Immunotherapy.

Fu, Yu, Huang, Yulan, Li, Pingrong, Wang, Luyao, Tang, Zhongjie, Liu, Xinlong, Bian, Xufei, Wu, Shuang, Wang, Xiaoyou, Zhu, Biyue, Yu, Yang, Jiang, Jiayun, Li, Chong · 2023 · Nano letters · DOI

Full title: Physical- and Chemical-Dually ROS-Responsive Nano-in-Gel Platforms with Sequential Release of OX40 Agonist and PD-1 Inhibitor for Augmented Combination Immunotherapy.

Authors: Fu, Yu, Huang, Yulan, Li, Pingrong, Wang, Luyao, Tang, Zhongjie, Liu, Xinlong, Bian, Xufei, Wu, Shuang, Wang, Xiaoyou, Zhu, Biyue, Yu, Yang, Jiang, Jiayun, Li, Chong

Year: 2023

Venue: Nano letters

DOI: https://doi.org/10.1021/acs.nanolett.2c04767

Paper Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy

Page, David B., Yuan, Jianda, Redmond, David, Wen, Y Hanna, Durack, Jeremy C., Emerson, Ryan, Solomon, Stephen B., Dong, Zhiwan, Wong, Phillip, Comstock, Christopher, Diab, Adi, Sung, Janice S., Maybody, Majid, Morris, Elizabeth A., Brogi, Edi, Morrow, Monica, Sacchini, Virgilio, Elemento, Olivier, Robins, Harlan, Patil, Sujata, Allison, James P., Wolchok, Jedd D., Hudis, Clifford A., Norton, Larry, McArthur, Heather L. · 2016 · Cancer Immunology Research · DOI

Full title: Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy

Authors: Page, David B., Yuan, Jianda, Redmond, David, Wen, Y Hanna, Durack, Jeremy C., Emerson, Ryan, Solomon, Stephen B., Dong, Zhiwan, Wong, Phillip, Comstock, Christopher, Diab, Adi, Sung, Janice S., Maybody, Majid, Morris, Elizabeth A., Brogi, Edi, Morrow, Monica, Sacchini, Virgilio, Elemento, Olivier, Robins, Harlan, Patil, Sujata, Allison, James P., Wolchok, Jedd D., Hudis, Clifford A., Norton, Larry, McArthur, Heather L.

Year: 2016

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-16-0013

Paper Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

Simpson, Tyler R, Li, Fubin, Montalvo-Ortiz, Welby, Sepulveda, Manuel A, Bergerhoff, Katharina, Arce, Frederick, Roddie, Claire, Henry, Jake Y, Yagita, Hideo, Wolchok, Jedd D, Peggs, Karl S, Ravetch, Jeffrey V, Allison, James P, Quezada, Sergio A · 2013 · The Journal of experimental medicine · DOI

Full title: Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

Authors: Simpson, Tyler R, Li, Fubin, Montalvo-Ortiz, Welby, Sepulveda, Manuel A, Bergerhoff, Katharina, Arce, Frederick, Roddie, Claire, Henry, Jake Y, Yagita, Hideo, Wolchok, Jedd D, Peggs, Karl S, Ravetch, Jeffrey V, Allison, James P, Quezada, Sergio A

Year: 2013

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20130579

Paper A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells

T. Knuschke, S. Kollenda, Christina Wenzek, Gennadiy Zelinskyy, Philine Steinbach, U. Dittmer, J. Buer, M. Epple, A. Westendorf · 2021 · mBio · DOI

Full title: A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells

Authors: T. Knuschke, S. Kollenda, Christina Wenzek, Gennadiy Zelinskyy, Philine Steinbach, U. Dittmer, J. Buer, M. Epple, A. Westendorf

Year: 2021

Venue: mBio

DOI: https://doi.org/10.1128/mbio.02121-20

Paper Immunotherapy in colorectal cancer: rationale, challenges and potential

Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Díaz, Luis A. · 2019 · Nature Reviews Gastroenterology & Hepatology · DOI

Full title: Immunotherapy in colorectal cancer: rationale, challenges and potential

Authors: Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Díaz, Luis A.

Year: 2019

Venue: Nature Reviews Gastroenterology & Hepatology

DOI: https://doi.org/10.1038/s41575-019-0126-x

Paper Ileus in patients treated with immune checkpoint inhibitors: A retrospective, pharmacovigilance study using Food and Drug Administration Adverse Event Reporting System database.

Gao, Siyuan, He, Zhichao, Zhu, Jianhong, Liang, Dan, Zhao, Wenxia, Yang, Shan, Jiang, Wei, Qiu, Kaifeng, Yu, Xiaoxia, Wu, Junyan · 2022 · Pharmacoepidemiology and drug safety · DOI

Full title: Ileus in patients treated with immune checkpoint inhibitors: A retrospective, pharmacovigilance study using Food and Drug Administration Adverse Event Reporting System database.

Authors: Gao, Siyuan, He, Zhichao, Zhu, Jianhong, Liang, Dan, Zhao, Wenxia, Yang, Shan, Jiang, Wei, Qiu, Kaifeng, Yu, Xiaoxia, Wu, Junyan

Year: 2022

Venue: Pharmacoepidemiology and drug safety

DOI: https://doi.org/10.1002/pds.5493

Paper Radiation-induced PD-L1 expression in tumor and its microenvironment facilitates cancer-immune escape: a narrative review

Wang, Nuo-Han, Lei, Zheng, Yang, Hao-Nan, Tang, Zheng, Yang, Mengqi, Wang, Ying, Sui, Jiang-Dong, Wu, YongZhong · 2022 · Annals of Translational Medicine · DOI

Full title: Radiation-induced PD-L1 expression in tumor and its microenvironment facilitates cancer-immune escape: a narrative review

Authors: Wang, Nuo-Han, Lei, Zheng, Yang, Hao-Nan, Tang, Zheng, Yang, Mengqi, Wang, Ying, Sui, Jiang-Dong, Wu, YongZhong

Year: 2022

Venue: Annals of Translational Medicine

DOI: https://doi.org/10.21037/atm-22-6049

Paper New strategies for the management of triple-negative breast cancer.

Riaz, Fauzia · 2024 · Current opinion in obstetrics & gynecology · DOI

Full title: New strategies for the management of triple-negative breast cancer.

Authors: Riaz, Fauzia

Year: 2024

Venue: Current opinion in obstetrics & gynecology

DOI: https://doi.org/10.1097/GCO.0000000000000927

Paper Meta-Analysis of the Risk of Immune-Related Adverse Events With Anticytotoxic T-Lymphocyte-Associated Antigen 4 and Antiprogrammed Death 1 Therapies.

Komaki, Y, Komaki, F, Yamada, A, Micic, D, Ido, A, Sakuraba, A · 2018 · Clinical pharmacology and therapeutics · DOI

Full title: Meta-Analysis of the Risk of Immune-Related Adverse Events With Anticytotoxic T-Lymphocyte-Associated Antigen 4 and Antiprogrammed Death 1 Therapies.

Authors: Komaki, Y, Komaki, F, Yamada, A, Micic, D, Ido, A, Sakuraba, A

Year: 2018

Venue: Clinical pharmacology and therapeutics

DOI: https://doi.org/10.1002/cpt.633

Paper Combined programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 blockade in an international cohort of patients with acral lentiginous melanoma.

McGillivray, Erin, Ashouri, Karam, Chatziioannou, Eftychia, Gallegos, Jesús Antonio Ocejo, Zarka, Jabra, Kechter, Jacob, Hwang, Angelina S, Zhang, Kevin, Barros, Milton, Yeh, Justin, Okazaki, Ian, Crocker, Andrew B, Maeda, Takuya, Park, Soo J, Choi, Jacob, Andreoli, Mia, Darwish, Tarneem, Savage, David J, Kim, Kevin B, Gupta, Jayant, Shen, James, Shirai, Keisuke, Choi, April, Pai, Lori, Vazquez, Vinicius de Lima, Moser, Justin, Amaral, Teresa, Hernandez Aya, Leonel F, Lutzky, Jose, Najjar, Yana G, Costello, Collin M, Mangold, Aaron R, Bhatia, Shailender, Gibney, Geoffrey T, Farma, Jeffrey M, Daniels, Gregory A, Sosman, Jeffrey, Chandra, Sunandana, Mangla, Ankit, Bollin, Kathryn, Possik, Patrícia Abrão, Robles-Espinoza, Carla Daniela, Ito, Fumito, In, Gino K · 2025 · The British journal of dermatology · DOI

Full title: Combined programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 blockade in an international cohort of patients with acral lentiginous melanoma.

Authors: McGillivray, Erin, Ashouri, Karam, Chatziioannou, Eftychia, Gallegos, Jesús Antonio Ocejo, Zarka, Jabra, Kechter, Jacob, Hwang, Angelina S, Zhang, Kevin, Barros, Milton, Yeh, Justin, Okazaki, Ian, Crocker, Andrew B, Maeda, Takuya, Park, Soo J, Choi, Jacob, Andreoli, Mia, Darwish, Tarneem, Savage, David J, Kim, Kevin B, Gupta, Jayant, Shen, James, Shirai, Keisuke, Choi, April, Pai, Lori, Vazquez, Vinicius de Lima, Moser, Justin, Amaral, Teresa, Hernandez Aya, Leonel F, Lutzky, Jose, Najjar, Yana G, Costello, Collin M, Mangold, Aaron R, Bhatia, Shailender, Gibney, Geoffrey T, Farma, Jeffrey M, Daniels, Gregory A, Sosman, Jeffrey, Chandra, Sunandana, Mangla, Ankit, Bollin, Kathryn, Possik, Patrícia Abrão, Robles-Espinoza, Carla Daniela, Ito, Fumito, In, Gino K

Year: 2025

Venue: The British journal of dermatology

DOI: https://doi.org/10.1093/bjd/ljae401

Paper Combination immunotherapy in renal cell carcinoma.

Drake, Charles G · 2016 · Clinical advances in hematology & oncology : H&O

Full title: Combination immunotherapy in renal cell carcinoma.

Authors: Drake, Charles G

Year: 2016

Venue: Clinical advances in hematology & oncology : H&O

Paper Pretreatment Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase Predict the Prognosis of Metastatic Cervical Cancer Treated with Combination Immunotherapy.

Cheng, Mingxia, Li, Guiling, Liu, Zhongan, Yang, Qin, Jiang, Yao · 2022 · Journal of oncology · DOI

Full title: Pretreatment Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase Predict the Prognosis of Metastatic Cervical Cancer Treated with Combination Immunotherapy.

Authors: Cheng, Mingxia, Li, Guiling, Liu, Zhongan, Yang, Qin, Jiang, Yao

Year: 2022

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2022/1828473

Paper Oncolytic microgels with regulated antibody release augment tumor immunotherapy.

Guo, Jiakun, Tan, Hujing, Chen, Wanting, Wang, Yan, Lin, Wenhai, Zhong, Zhiyuan, Deng, Chao · 2025 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Oncolytic microgels with regulated antibody release augment tumor immunotherapy.

Authors: Guo, Jiakun, Tan, Hujing, Chen, Wanting, Wang, Yan, Lin, Wenhai, Zhong, Zhiyuan, Deng, Chao

Year: 2025

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2025.114003

Paper Second- and third-generation drugs for immuno-oncology treatment-The more the better?

Dempke, Wolfram C M, Fenchel, Klaus, Uciechowski, Peter, Dale, Stephen P · 2017 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Second- and third-generation drugs for immuno-oncology treatment-The more the better?

Authors: Dempke, Wolfram C M, Fenchel, Klaus, Uciechowski, Peter, Dale, Stephen P

Year: 2017

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2017.01.001

Paper Immunotherapy for malignant melanoma.

Zeiser, Robert, Schnitzler, Marc, Andrlova, Hana, Hellige, Tina, Meiss, Frank · 2012 · Current stem cell research & therapy · DOI

Full title: Immunotherapy for malignant melanoma.

Authors: Zeiser, Robert, Schnitzler, Marc, Andrlova, Hana, Hellige, Tina, Meiss, Frank

Year: 2012

Venue: Current stem cell research & therapy

DOI: https://doi.org/10.2174/157488812799859883

Paper Nivolumab plus ipilimumab: A promising first-line therapy for hepatocellular carcinoma.

Stefanini, Bernardo, Piscaglia, Fabio · 2025 · Med (New York, N.Y.) · DOI

Full title: Nivolumab plus ipilimumab: A promising first-line therapy for hepatocellular carcinoma.

Authors: Stefanini, Bernardo, Piscaglia, Fabio

Year: 2025

Venue: Med (New York, N.Y.)

DOI: https://doi.org/10.1016/j.medj.2025.100783

Paper Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice.

Meyblum, Louis, Chevaleyre, Céline, Susini, Sandrine, Jego, Benoit, Deschamps, Frederic, Kereselidze, Dimitri, Bonnet, Baptiste, Marabelle, Aurelien, de Baere, Thierry, Lebon, Vincent, Tselikas, Lambros, Truillet, Charles · 2023 · Journal for immunotherapy of cancer · DOI

Full title: Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice.

Authors: Meyblum, Louis, Chevaleyre, Céline, Susini, Sandrine, Jego, Benoit, Deschamps, Frederic, Kereselidze, Dimitri, Bonnet, Baptiste, Marabelle, Aurelien, de Baere, Thierry, Lebon, Vincent, Tselikas, Lambros, Truillet, Charles

Year: 2023

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2023-007433

Paper Molecular cytometry identifies a wide range of translationally relevant markers in tumor and peripheral immune cells of lung cancer patients

P. Chattopadhyay, G. Gao, I. Taylor, Kayla Guidry, K. Labbe, C. Almonte, Margaret A. Nakamoto, Kwok Kin-Wong · 2020 · Journal of Immunology · DOI

Full title: Molecular cytometry identifies a wide range of translationally relevant markers in tumor and peripheral immune cells of lung cancer patients

Authors: P. Chattopadhyay, G. Gao, I. Taylor, Kayla Guidry, K. Labbe, C. Almonte, Margaret A. Nakamoto, Kwok Kin-Wong

Year: 2020

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.204.supp.242.30

Paper Author Response: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Mullen, Nicholas J., Shukla, Surendra K., Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina V., Santana, Juan F., Miklavcic, William R., LaBreck, Drew A., Mallareddy, Jayapal Reddy, Price, David H., Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B., Hollingsworth, Michael A., Singh, Pankaj K. · 2024 · DOI

Full title: Author Response: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: Mullen, Nicholas J., Shukla, Surendra K., Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina V., Santana, Juan F., Miklavcic, William R., LaBreck, Drew A., Mallareddy, Jayapal Reddy, Price, David H., Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B., Hollingsworth, Michael A., Singh, Pankaj K.

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2.sa4

Paper Comparative combination cancer immunotherapy with vaccination, checkpoint inhibition and TNFRSF stimulation (VAC12P.1021)

Taylor H. Schreiber, E. Podack · 2014 · Journal of Immunology · DOI

Full title: Comparative combination cancer immunotherapy with vaccination, checkpoint inhibition and TNFRSF stimulation (VAC12P.1021)

Authors: Taylor H. Schreiber, E. Podack

Year: 2014

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.192.supp.206.10

Paper Comparative efficacy of chemoimmunotherapy versus immunotherapy alone in the front-line treatment of advanced non-small cell lung cancer: A systematic review and network meta-analysis.

R. Pathak, G. Lopes, Han Yu, Wenyan Ji, M. Aryal, K. Frumento, C. Wallis, Z. Klaassen, Henry S. Park, S. Goldberg · 2020 · Journal of Clinical Oncology · DOI

Full title: Comparative efficacy of chemoimmunotherapy versus immunotherapy alone in the front-line treatment of advanced non-small cell lung cancer: A systematic review and network meta-analysis.

Authors: R. Pathak, G. Lopes, Han Yu, Wenyan Ji, M. Aryal, K. Frumento, C. Wallis, Z. Klaassen, Henry S. Park, S. Goldberg

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.9552

Paper Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Brahmer, Julie R., Drake, Charles G., Wollner, Ira, Powderly, John D., Picus, Joel, Sharfman, William H., Stankevich, Elizabeth, Pons, Alice, Salay, Theresa M., McMiller, Tracee L., Gilson, Marta M., Wang, Changyu, Selby, Mark, Taube, Janis M., Anders, Robert A., Chen, Lieping, Korman, Alan J., Pardoll, Drew M., Lowy, Israel, Topalian, Suzanne L. · 2010 · Journal of Clinical Oncology · DOI

Full title: Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Authors: Brahmer, Julie R., Drake, Charles G., Wollner, Ira, Powderly, John D., Picus, Joel, Sharfman, William H., Stankevich, Elizabeth, Pons, Alice, Salay, Theresa M., McMiller, Tracee L., Gilson, Marta M., Wang, Changyu, Selby, Mark, Taube, Janis M., Anders, Robert A., Chen, Lieping, Korman, Alan J., Pardoll, Drew M., Lowy, Israel, Topalian, Suzanne L.

Year: 2010

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2009.26.7609

Paper Improved survival with T cell clonotype stability after anti-CTLA-4 treatment in cancer patients.

Cha, Edward, Klinger, Mark, Hou, Yafei, Cummings, Craig, Ribas, Antoni, Faham, Malek, Fong, Lawrence · 2014 · Science translational medicine · DOI

Full title: Improved survival with T cell clonotype stability after anti-CTLA-4 treatment in cancer patients.

Authors: Cha, Edward, Klinger, Mark, Hou, Yafei, Cummings, Craig, Ribas, Antoni, Faham, Malek, Fong, Lawrence

Year: 2014

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.3008211

Paper Long-term overall survival with dual CTLA-4 and PD-L1 or PD-1 blockade and biomarker-based subgroup analyses in patients with advanced non-small-cell lung cancer: a systematic review and reconstructed individual patient data meta-analysis.

Di Federico, Alessandro, Stumpo, Sara, Mantuano, Francesco, De Giglio, Andrea, Lo Bianco, Francesca, Pecci, Federica, Alessi, Joao V, Wang, Xinan, Sperandi, Francesca, Melotti, Barbara, Gelsomino, Francesco, Skoulidis, Ferdinandos, Garassino, Marina C, Peters, Solange, Awad, Mark M, Ardizzoni, Andrea, Ricciuti, Biagio · 2025 · The Lancet. Oncology · DOI

Full title: Long-term overall survival with dual CTLA-4 and PD-L1 or PD-1 blockade and biomarker-based subgroup analyses in patients with advanced non-small-cell lung cancer: a systematic review and reconstructed individual patient data meta-analysis.

Authors: Di Federico, Alessandro, Stumpo, Sara, Mantuano, Francesco, De Giglio, Andrea, Lo Bianco, Francesca, Pecci, Federica, Alessi, Joao V, Wang, Xinan, Sperandi, Francesca, Melotti, Barbara, Gelsomino, Francesco, Skoulidis, Ferdinandos, Garassino, Marina C, Peters, Solange, Awad, Mark M, Ardizzoni, Andrea, Ricciuti, Biagio

Year: 2025

Venue: The Lancet. Oncology

DOI: https://doi.org/10.1016/S1470-2045(25)00429-2

Paper Nomogram for Predicting Survival Post-Immune Therapy in Cholangiocarcinoma Based on Inflammatory Biomarkers

Jianan Jin, Haibo Mou, Yibin Zhou, Shiqi Zhang · 2024 · Cancer Control: Journal of the Moffitt Cancer Cente · DOI

Full title: Nomogram for Predicting Survival Post-Immune Therapy in Cholangiocarcinoma Based on Inflammatory Biomarkers

Authors: Jianan Jin, Haibo Mou, Yibin Zhou, Shiqi Zhang

Year: 2024

Venue: Cancer Control: Journal of the Moffitt Cancer Cente

DOI: https://doi.org/10.1177/10732748241305237

Paper Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Valsecchi, Matías E. · 2015 · New England Journal of Medicine · DOI

Full title: Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Authors: Valsecchi, Matías E.

Year: 2015

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmc1509660

Paper Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges.

Hu-Lieskovan, Siwen, Robert, Lidia, Homet Moreno, Blanca, Ribas, Antoni · 2014 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · DOI

Full title: Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges.

Authors: Hu-Lieskovan, Siwen, Robert, Lidia, Homet Moreno, Blanca, Ribas, Antoni

Year: 2014

Venue: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

DOI: https://doi.org/10.1200/JCO.2013.52.1377

Paper A randomized phase I/II study of neoadjuvant treatment with 177-Lutetium-PSMA-617 with or without ipilimumab in patients with very high-risk prostate cancer who are candidates for radical prostatectomy (NEPI trial).

U. Krafft, Viktor Grünwald, W. Fendler, Ken Herrmann, Henning Reis, F. Roghmann, K. Rahbar, Axel Heidenreich, F. Giesel, G. Niegisch, Boris Hadaschik · 2024 · Journal of Clinical Oncology · DOI

Full title: A randomized phase I/II study of neoadjuvant treatment with 177-Lutetium-PSMA-617 with or without ipilimumab in patients with very high-risk prostate cancer who are candidates for radical prostatectomy (NEPI trial).

Authors: U. Krafft, Viktor Grünwald, W. Fendler, Ken Herrmann, Henning Reis, F. Roghmann, K. Rahbar, Axel Heidenreich, F. Giesel, G. Niegisch, Boris Hadaschik

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.4_suppl.tps352

Paper Tumor mutation burden in lung cancer: a new predictive biomarker for immunotherapy or too soon to tell?

Alexander, Mariam P., Galeas, Jose Nahun, Cheng, Haiying · 2018 · Journal of Thoracic Disease · DOI

Full title: Tumor mutation burden in lung cancer: a new predictive biomarker for immunotherapy or too soon to tell?

Authors: Alexander, Mariam P., Galeas, Jose Nahun, Cheng, Haiying

Year: 2018

Venue: Journal of Thoracic Disease

DOI: https://doi.org/10.21037/jtd.2018.09.35

Paper Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma.

Vijayakumar, Gayathri, Palese, Peter, Goff, Peter H · 2019 · EBioMedicine · DOI

Full title: Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma.

Authors: Vijayakumar, Gayathri, Palese, Peter, Goff, Peter H

Year: 2019

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2019.10.032

Paper BET inhibition sensitizes innate checkpoint inhibitor resistant melanoma to anti-CTLA-4 treatment.

Tseng, Hsin-Yi, Alavi, Sara, Gallagher, Stuart, McGuire, Helen M, Hersey, Peter, Al Emran, Abdullah, Tiffen, Jessamy · 2024 · Pigment cell & melanoma research · DOI

Full title: BET inhibition sensitizes innate checkpoint inhibitor resistant melanoma to anti-CTLA-4 treatment.

Authors: Tseng, Hsin-Yi, Alavi, Sara, Gallagher, Stuart, McGuire, Helen M, Hersey, Peter, Al Emran, Abdullah, Tiffen, Jessamy

Year: 2024

Venue: Pigment cell & melanoma research

DOI: https://doi.org/10.1111/pcmr.13174

Paper Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

van der Kooij, Monique K, Suijkerbuijk, Karijn P M, Aarts, Maureen J B, van den Berkmortel, Franchette W P J, Blank, Christian U, Boers-Sonderen, Marye J, van Breeschoten, Jesper, van den Eertwegh, Alfonsus J M, de Groot, Jan Willem B, Haanen, John B A G, Hospers, Geke A P, Piersma, Djura, van Rijn, Rozemarijn S, Ten Tije, Albert J, van der Veldt, Astrid A M, Vreugdenhil, Gerard, van Zeijl, Michiel C T, Wouters, Michel W J M, Dekkers, Olaf M, Kapiteijn, Ellen · 2021 · Annals of internal medicine · DOI

Full title: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

Authors: van der Kooij, Monique K, Suijkerbuijk, Karijn P M, Aarts, Maureen J B, van den Berkmortel, Franchette W P J, Blank, Christian U, Boers-Sonderen, Marye J, van Breeschoten, Jesper, van den Eertwegh, Alfonsus J M, de Groot, Jan Willem B, Haanen, John B A G, Hospers, Geke A P, Piersma, Djura, van Rijn, Rozemarijn S, Ten Tije, Albert J, van der Veldt, Astrid A M, Vreugdenhil, Gerard, van Zeijl, Michiel C T, Wouters, Michel W J M, Dekkers, Olaf M, Kapiteijn, Ellen

Year: 2021

Venue: Annals of internal medicine

DOI: https://doi.org/10.7326/M20-3419

Paper Ctla-4 blockade plus adoptive T-cell transfer promotes optimal melanoma immunity in mice.

Mahvi, David A, Meyers, Justin V, Tatar, Andrew J, Contreras, Amanda, Suresh, Marulasiddappa, Leverson, Glen E, Sen, Siddhartha, Cho, Clifford S · 2015 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Ctla-4 blockade plus adoptive T-cell transfer promotes optimal melanoma immunity in mice.

Authors: Mahvi, David A, Meyers, Justin V, Tatar, Andrew J, Contreras, Amanda, Suresh, Marulasiddappa, Leverson, Glen E, Sen, Siddhartha, Cho, Clifford S

Year: 2015

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000064

Paper Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy.

Zhang, Jingyu, Liu, Dai, Li, Guangfu, Staveley-O'Carroll, Kevin F, Graff, Julie N, Li, Zihai, Wu, Jennifer D · 2017 · Science advances · DOI

Full title: Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy.

Authors: Zhang, Jingyu, Liu, Dai, Li, Guangfu, Staveley-O'Carroll, Kevin F, Graff, Julie N, Li, Zihai, Wu, Jennifer D

Year: 2017

Venue: Science advances

DOI: https://doi.org/10.1126/sciadv.1602133

Paper Immune checkpoint inhibitor doublets: Are they beneficial for older patients? A systematic review and meta-analysis.

Dottorini, Lorenzo, Ghidini, Antonio, Deda, Rita, Sarno, Italo, Cavallone, Matteo, Luciani, Andrea, Petrelli, Fausto · 2024 · Journal of geriatric oncology · DOI

Full title: Immune checkpoint inhibitor doublets: Are they beneficial for older patients? A systematic review and meta-analysis.

Authors: Dottorini, Lorenzo, Ghidini, Antonio, Deda, Rita, Sarno, Italo, Cavallone, Matteo, Luciani, Andrea, Petrelli, Fausto

Year: 2024

Venue: Journal of geriatric oncology

DOI: https://doi.org/10.1016/j.jgo.2024.101741

Paper Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma

S. Rosner, E. Kwong, A. Shoushtari, C. Friedman, A. Betof, M. Brady, D. Coit, M. Callahan, J. Wolchok, P. Chapman, K. Panageas, M. Postow · 2018 · Cancer Medicine · DOI

Full title: Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma

Authors: S. Rosner, E. Kwong, A. Shoushtari, C. Friedman, A. Betof, M. Brady, D. Coit, M. Callahan, J. Wolchok, P. Chapman, K. Panageas, M. Postow

Year: 2018

Venue: Cancer Medicine

DOI: https://doi.org/10.1002/cam4.1356

Paper An Efficient Combination Immunotherapy for Primary Liver Cancer by Harmonized Activation of Innate and Adaptive Immunity in Mice.

Wen, Liang, Xin, Bing, Wu, Panyisha, Lin, Chia-Hao, Peng, Chuanhui, Wang, Gaowei, Lee, Jin, Lu, Li-Fan, Feng, Gen-Sheng · 2019 · Hepatology (Baltimore, Md.) · DOI

Full title: An Efficient Combination Immunotherapy for Primary Liver Cancer by Harmonized Activation of Innate and Adaptive Immunity in Mice.

Authors: Wen, Liang, Xin, Bing, Wu, Panyisha, Lin, Chia-Hao, Peng, Chuanhui, Wang, Gaowei, Lee, Jin, Lu, Li-Fan, Feng, Gen-Sheng

Year: 2019

Venue: Hepatology (Baltimore, Md.)

DOI: https://doi.org/10.1002/hep.30528

Paper Efficacy of PD-1/PD-L1 inhibitors in advanced gastroesophageal cancer based on characteristics: a meta-analysis.

Liu, Wenjie, Huo, Gengwei, Chen, Peng · 2023 · Immunotherapy · DOI

Full title: Efficacy of PD-1/PD-L1 inhibitors in advanced gastroesophageal cancer based on characteristics: a meta-analysis.

Authors: Liu, Wenjie, Huo, Gengwei, Chen, Peng

Year: 2023

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2022-0305

Paper First-line nivolumab plus ipilimumab with or without chemotherapy for Japanese patients with non-small cell lung cancer: LIGHT-NING study

Imai, Hisao, Kijima, Takashi, Azuma, Koichi, Kishi, Kazuma, Saito, Haruhiro, Yamaguchi, Teppei, Tanizaki, Junko, Yoneshima, Yasuto, Fujita, Kohei, Watanabe, Satoshi, Kitazono, Satoru, Fukuhara, Tatsuro, Hataji, Osamu, Toi, Yukihiro, Mizutani, Hideaki, Hamakawa, Yusuke, Maemondo, Makoto, Ohsugi, Tomoyuki, Suzuki, Keisuke, Horinouchi, Hidehito, Ohe, Yuichiro · 2024 · Japanese Journal of Clinical Oncology · DOI

Full title: First-line nivolumab plus ipilimumab with or without chemotherapy for Japanese patients with non-small cell lung cancer: LIGHT-NING study

Authors: Imai, Hisao, Kijima, Takashi, Azuma, Koichi, Kishi, Kazuma, Saito, Haruhiro, Yamaguchi, Teppei, Tanizaki, Junko, Yoneshima, Yasuto, Fujita, Kohei, Watanabe, Satoshi, Kitazono, Satoru, Fukuhara, Tatsuro, Hataji, Osamu, Toi, Yukihiro, Mizutani, Hideaki, Hamakawa, Yusuke, Maemondo, Makoto, Ohsugi, Tomoyuki, Suzuki, Keisuke, Horinouchi, Hidehito, Ohe, Yuichiro

Year: 2024

Venue: Japanese Journal of Clinical Oncology

DOI: https://doi.org/10.1093/jjco/hyad195

Paper Cadonilimab, a tetravalent PD-1/CTLA-4 bispecific antibody with trans-binding and enhanced target binding avidity.

Pang, Xinghua, Huang, Zhaoliang, Zhong, Tingting, Zhang, Peng, Wang, Zhongmin Maxwell, Xia, Michelle, Li, Baiyong · 2023 · mAbs · DOI

Full title: Cadonilimab, a tetravalent PD-1/CTLA-4 bispecific antibody with trans-binding and enhanced target binding avidity.

Authors: Pang, Xinghua, Huang, Zhaoliang, Zhong, Tingting, Zhang, Peng, Wang, Zhongmin Maxwell, Xia, Michelle, Li, Baiyong

Year: 2023

Venue: mAbs

DOI: https://doi.org/10.1080/19420862.2023.2180794

Paper Predictive Role of Computed Tomography Texture Analysis in Patients with Metastatic Urothelial Cancer Treated with Programmed Death-1 and Programmed Death-ligand 1 Inhibitors.

Alessandrino, Francesco, Gujrathi, Rahul, Nassar, Amin H, Alzaghal, Arwa, Ravi, Arvind, McGregor, Bradley, Sonpavde, Guru, Shinagare, Atul B · 2020 · European urology oncology · DOI

Full title: Predictive Role of Computed Tomography Texture Analysis in Patients with Metastatic Urothelial Cancer Treated with Programmed Death-1 and Programmed Death-ligand 1 Inhibitors.

Authors: Alessandrino, Francesco, Gujrathi, Rahul, Nassar, Amin H, Alzaghal, Arwa, Ravi, Arvind, McGregor, Bradley, Sonpavde, Guru, Shinagare, Atul B

Year: 2020

Venue: European urology oncology

DOI: https://doi.org/10.1016/j.euo.2019.02.002

Paper Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy.

Wang, Yujue, Liu, Sixue, Yang, Zhentao, Algazi, Alain P, Lomeli, Shirley H, Wang, Yan, Othus, Megan, Hong, Aayoung, Wang, Xiaoyan, Randolph, Chris E, Jones, Alexis M, Bosenberg, Marcus W, Byrum, Stephanie D, Tackett, Alan J, Lopez, Henry, Yates, Clayton, Solit, David B, Ribas, Antoni, Piva, Marco, Moriceau, Gatien, Lo, Roger S · 2021 · Cancer cell · DOI

Full title: Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy.

Authors: Wang, Yujue, Liu, Sixue, Yang, Zhentao, Algazi, Alain P, Lomeli, Shirley H, Wang, Yan, Othus, Megan, Hong, Aayoung, Wang, Xiaoyan, Randolph, Chris E, Jones, Alexis M, Bosenberg, Marcus W, Byrum, Stephanie D, Tackett, Alan J, Lopez, Henry, Yates, Clayton, Solit, David B, Ribas, Antoni, Piva, Marco, Moriceau, Gatien, Lo, Roger S

Year: 2021

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2021.07.023

Paper Immunotherapy toxicity. Diagnosis and treatment.

Toribio-Vázquez, Carlos, Gómez Rivas, Juan, Yebes, Alvaro, Carrión, Diego M, Quesada-Olarte, José, Trelles, Carlos R, Álvarez-Maestro, Mario, van der Poel, Henk, Martínez-Piñeiro, Luis · 2020 · Archivos espanoles de urologia

Full title: Immunotherapy toxicity. Diagnosis and treatment.

Authors: Toribio-Vázquez, Carlos, Gómez Rivas, Juan, Yebes, Alvaro, Carrión, Diego M, Quesada-Olarte, José, Trelles, Carlos R, Álvarez-Maestro, Mario, van der Poel, Henk, Martínez-Piñeiro, Luis

Year: 2020

Venue: Archivos espanoles de urologia

Paper Are immune checkpoint inhibitors a valid option for papillary renal cell carcinoma? A multicentre retrospective study.

de Vries-Brilland, Manon, Gross-Goupil, Marine, Seegers, Valérie, Boughalem, Elouen, Beuselinck, Benoit, Thibault, Constance, Chevreau, Christine, Ladoire, Sylvain, Barthélémy, Philippe, Negrier, Sylvie, Borchiellini, Delphine, Huillard, Olivier, Geoffrois, Lionnel, Gravis, Gwenaelle, Saldana, Carolina, Thiery-Vuillemin, Antoine, Escudier, Bernard, Ravaud, Alain, Albiges, Laurence · 2020 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Are immune checkpoint inhibitors a valid option for papillary renal cell carcinoma? A multicentre retrospective study.

Authors: de Vries-Brilland, Manon, Gross-Goupil, Marine, Seegers, Valérie, Boughalem, Elouen, Beuselinck, Benoit, Thibault, Constance, Chevreau, Christine, Ladoire, Sylvain, Barthélémy, Philippe, Negrier, Sylvie, Borchiellini, Delphine, Huillard, Olivier, Geoffrois, Lionnel, Gravis, Gwenaelle, Saldana, Carolina, Thiery-Vuillemin, Antoine, Escudier, Bernard, Ravaud, Alain, Albiges, Laurence

Year: 2020

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2020.02.019

Paper Research progress of tumor targeted drug delivery based on PD-1/PD-L1.

Liu, Dongzhu, Gao, Shan, Zhai, Yujia, Yang, Xiaoye, Zhai, Guangxi · 2022 · International journal of pharmaceutics · DOI

Full title: Research progress of tumor targeted drug delivery based on PD-1/PD-L1.

Authors: Liu, Dongzhu, Gao, Shan, Zhai, Yujia, Yang, Xiaoye, Zhai, Guangxi

Year: 2022

Venue: International journal of pharmaceutics

DOI: https://doi.org/10.1016/j.ijpharm.2022.121527

Paper A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

Ni, Qianqian, Zhang, Fuwu, Liu, Yijing, Wang, Zhantong, Yu, Guocan, Liang, Brian, Niu, Gang, Su, Ting, Zhu, Guizhi, Lu, Guangming, Zhang, Long Jiang, Chen, Xiaohong · 2020 · Science Advances · DOI

Full title: A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

Authors: Ni, Qianqian, Zhang, Fuwu, Liu, Yijing, Wang, Zhantong, Yu, Guocan, Liang, Brian, Niu, Gang, Su, Ting, Zhu, Guizhi, Lu, Guangming, Zhang, Long Jiang, Chen, Xiaohong

Year: 2020

Venue: Science Advances

DOI: https://doi.org/10.1126/sciadv.aaw6071

Paper ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity.

Soldevilla, Mario Martínez, Villanueva, Helena, Meraviglia-Crivelli, Daniel, Menon, Ashwathi Puravankara, Ruiz, Marta, Cebollero, Javier, Villalba, María, Moreno, Beatriz, Lozano, Teresa, Llopiz, Diana, Pejenaute, Álvaro, Sarobe, Pablo, Pastor, Fernando · 2019 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity.

Authors: Soldevilla, Mario Martínez, Villanueva, Helena, Meraviglia-Crivelli, Daniel, Menon, Ashwathi Puravankara, Ruiz, Marta, Cebollero, Javier, Villalba, María, Moreno, Beatriz, Lozano, Teresa, Llopiz, Diana, Pejenaute, Álvaro, Sarobe, Pablo, Pastor, Fernando

Year: 2019

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1016/j.ymthe.2019.07.013

Paper Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Oweida, Ayman, Hararah, Mohammad K., Phan, Andy V., Binder, David C., Bhatia, Shilpa, Lennon, Shelby, Bukkapatnam, Sanjana, Court, Benjamin Van, Uyanga, Nomin, Darragh, Laurel B., Kim, H. Mike, Raben, David, Tan, Aik Choon, Heasley, Lynn E., Clambey, Eric T., Nemenoff, Raphael A., Karam, Sana D. · 2023 · DOI

Full title: Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Authors: Oweida, Ayman, Hararah, Mohammad K., Phan, Andy V., Binder, David C., Bhatia, Shilpa, Lennon, Shelby, Bukkapatnam, Sanjana, Court, Benjamin Van, Uyanga, Nomin, Darragh, Laurel B., Kim, H. Mike, Raben, David, Tan, Aik Choon, Heasley, Lynn E., Clambey, Eric T., Nemenoff, Raphael A., Karam, Sana D.

Year: 2023

DOI: https://doi.org/10.1158/1078-0432.c.6528824

Paper Immune Checkpoint Inhibitor-related New-onset Thyroid Dysfunction: A Retrospective Analysis Using the US FDA Adverse Event Reporting System.

Lu, Difei, Yao, Jun, Yuan, Geheng, Gao, Ying, Zhang, Junqing, Guo, Xiaohui · 2022 · The oncologist · DOI

Full title: Immune Checkpoint Inhibitor-related New-onset Thyroid Dysfunction: A Retrospective Analysis Using the US FDA Adverse Event Reporting System.

Authors: Lu, Difei, Yao, Jun, Yuan, Geheng, Gao, Ying, Zhang, Junqing, Guo, Xiaohui

Year: 2022

Venue: The oncologist

DOI: https://doi.org/10.1093/oncolo/oyab043

Paper 553 Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade (ICB) in patients with oropharyngeal carcinoma (OPC)

Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, Liang, Qingnan, Duo, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane, Li, Meng, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L. · 2024 · Regular and Young Investigator Award Abstracts · DOI

Full title: 553 Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade (ICB) in patients with oropharyngeal carcinoma (OPC)

Authors: Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, Liang, Qingnan, Duo, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane, Li, Meng, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L.

Year: 2024

Venue: Regular and Young Investigator Award Abstracts

DOI: https://doi.org/10.1136/jitc-2024-sitc2024.0553

Paper Response to Nivolumab and Ipilimumab in Microsatellite Instability-High (MSI-H) Cervical Carcinoma with Acquired Resistance to Pembrolizumab: A Case Report and Literature Review.

Gim, Gahyun, Kim, Yeseul, Park, Yeonggyeong, Kim, Min Jeong, Nam, Myungwoo, Yang, Woojung, Duarte, Samantha E, Jung, Chan Mi, Vagia, Elena, Viveiros, Pedro, Chae, Young Kwang · 2022 · The oncologist · DOI

Full title: Response to Nivolumab and Ipilimumab in Microsatellite Instability-High (MSI-H) Cervical Carcinoma with Acquired Resistance to Pembrolizumab: A Case Report and Literature Review.

Authors: Gim, Gahyun, Kim, Yeseul, Park, Yeonggyeong, Kim, Min Jeong, Nam, Myungwoo, Yang, Woojung, Duarte, Samantha E, Jung, Chan Mi, Vagia, Elena, Viveiros, Pedro, Chae, Young Kwang

Year: 2022

Venue: The oncologist

DOI: https://doi.org/10.1093/oncolo/oyac095

Paper Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor Immunotherapy and Post-Surgical Tumor Treatment.

Chen, Zhixiong, Rong, Yan, Ding, Junfeng, Cheng, Xueliang, Chen, Xuesi, He, Chaoliang · 2023 · Pharmaceutics · DOI

Full title: Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor Immunotherapy and Post-Surgical Tumor Treatment.

Authors: Chen, Zhixiong, Rong, Yan, Ding, Junfeng, Cheng, Xueliang, Chen, Xuesi, He, Chaoliang

Year: 2023

Venue: Pharmaceutics

DOI: https://doi.org/10.3390/pharmaceutics15020428

Paper Treatment- and immune-related adverse events of immune checkpoint inhibitors in advanced lung cancer.

Shao, Jun, Wang, Chengdi, Ren, Pengwei, Jiang, Yuting, Tian, Panwen, Li, Weimin · 2020 · Bioscience reports · DOI

Full title: Treatment- and immune-related adverse events of immune checkpoint inhibitors in advanced lung cancer.

Authors: Shao, Jun, Wang, Chengdi, Ren, Pengwei, Jiang, Yuting, Tian, Panwen, Li, Weimin

Year: 2020

Venue: Bioscience reports

DOI: https://doi.org/10.1042/BSR20192347

Paper Hospital admissions and subsequent outcomes from immune-related adverse events.

H. Ho, Melissa Arneil, Wen Xu, V. Atkinson · 2021 · DOI

Full title: Hospital admissions and subsequent outcomes from immune-related adverse events.

Authors: H. Ho, Melissa Arneil, Wen Xu, V. Atkinson

Year: 2021

DOI: https://doi.org/10.1200/jco.2021.39.15_suppl.e21590

Paper Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.

Shi, Lewis Zhichang, Goswami, Sangeeta, Fu, Tihui, Guan, Baoxiang, Chen, Jianfeng, Xiong, Liangwen, Zhang, Jan, Ng Tang, Derek, Zhang, Xuejun, Vence, Luis, Blando, Jorge, Allison, James P, Collazo, Renata, Gao, Jianjun, Sharma, Padmanee · 2019 · Cancer immunology research · DOI

Full title: Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.

Authors: Shi, Lewis Zhichang, Goswami, Sangeeta, Fu, Tihui, Guan, Baoxiang, Chen, Jianfeng, Xiong, Liangwen, Zhang, Jan, Ng Tang, Derek, Zhang, Xuejun, Vence, Luis, Blando, Jorge, Allison, James P, Collazo, Renata, Gao, Jianjun, Sharma, Padmanee

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0873

Paper The survival benefits and the risk of severe renal injury of immune checkpoint inhibitors in patients with cancer: The real-world evidence from the National Clinical Cohort Collaborative (N3C).

Yao Chen, Xiaochun Li, V. Madhira, T. Shugg, S. Jalal, M. Eadon, Benjamin Bates, Noha Sharafeldin, U. Topaloglu, Q. Song, J. Su · 2024 · Journal of Clinical Oncology · DOI

Full title: The survival benefits and the risk of severe renal injury of immune checkpoint inhibitors in patients with cancer: The real-world evidence from the National Clinical Cohort Collaborative (N3C).

Authors: Yao Chen, Xiaochun Li, V. Madhira, T. Shugg, S. Jalal, M. Eadon, Benjamin Bates, Noha Sharafeldin, U. Topaloglu, Q. Song, J. Su

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.e24142

Paper Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Küçükköse, Emre, Heesters, Balthasar A, Villaudy, Julien, Verheem, André, Cercel, Madalina, van Hal, Susan, Boj, Sylvia F, Borel Rinkes, Inne H M, Punt, Cornelis J A, Roodhart, Jeanine M L, Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno · 2022 · Journal for immunotherapy of cancer · DOI

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Authors: Küçükköse, Emre, Heesters, Balthasar A, Villaudy, Julien, Verheem, André, Cercel, Madalina, van Hal, Susan, Boj, Sylvia F, Borel Rinkes, Inne H M, Punt, Cornelis J A, Roodhart, Jeanine M L, Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno

Year: 2022

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2022-005345

Paper Efficacy of immune checkpoint inhibitors along with chemotherapy in non-small cell lung cancer and the impact on adverse reactions and serum tumor markers.

Xie, Miao, Wang, Xinlin, Wang, Peng, Liu, An, Wen, Yurong, Xiao, Bing · 2023 · American journal of translational research

Full title: Efficacy of immune checkpoint inhibitors along with chemotherapy in non-small cell lung cancer and the impact on adverse reactions and serum tumor markers.

Authors: Xie, Miao, Wang, Xinlin, Wang, Peng, Liu, An, Wen, Yurong, Xiao, Bing

Year: 2023

Venue: American journal of translational research

Paper Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy

Strudel, Martina, Festino, Lucia, Vanella, Vito, Beretta, Massimiliano, Marincola, Francesco M., Ascierto, Paolo A. · 2019 · Current Medicinal Chemistry · DOI

Full title: Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy

Authors: Strudel, Martina, Festino, Lucia, Vanella, Vito, Beretta, Massimiliano, Marincola, Francesco M., Ascierto, Paolo A.

Year: 2019

Venue: Current Medicinal Chemistry

DOI: https://doi.org/10.2174/0929867326666191205160007

Paper Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8+ T cells.

Redmond, William L, Linch, Stefanie N · 2016 · Human vaccines & immunotherapeutics · DOI

Full title: Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8+ T cells.

Authors: Redmond, William L, Linch, Stefanie N

Year: 2016

Venue: Human vaccines & immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2016.1193277

Paper Imaging evaluation of lung cancer treated with PD-1/PD-L1 inhibitors.

Mohammed, Nader, Zhou, Rong Rong, Xiong, Zeng · 2021 · The British journal of radiology · DOI

Full title: Imaging evaluation of lung cancer treated with PD-1/PD-L1 inhibitors.

Authors: Mohammed, Nader, Zhou, Rong Rong, Xiong, Zeng

Year: 2021

Venue: The British journal of radiology

DOI: https://doi.org/10.1259/bjr.20210228

Paper Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade.

Fu, Minjie, Zhao, Jiaxu, Zhang, Licheng, Sheng, Zhewei, Li, Xiaohui, Qiu, Fufang, Feng, Yuan, You, Muyuan, Xu, Hao, Zhang, Jinsen, Zeng, Rui, Huang, Yang, Li, Cheng, Chen, Wenhan, Chen, Zheng, Peng, Haibao, Li, Longzhi, Wu, Yonghe, Ye, Dan, Chi, Yudan, Hua, Wei, Mao, Ying · 2024 · Cancer cell · DOI

Full title: Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade.

Authors: Fu, Minjie, Zhao, Jiaxu, Zhang, Licheng, Sheng, Zhewei, Li, Xiaohui, Qiu, Fufang, Feng, Yuan, You, Muyuan, Xu, Hao, Zhang, Jinsen, Zeng, Rui, Huang, Yang, Li, Cheng, Chen, Wenhan, Chen, Zheng, Peng, Haibao, Li, Longzhi, Wu, Yonghe, Ye, Dan, Chi, Yudan, Hua, Wei, Mao, Ying

Year: 2024

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2024.09.012

Paper Abstract CT102: APACHE: An open label, randomized, phase II study of Durvalumab (Durva), alone or in combination with Tremelimumab (Treme), in patients (pts) with advanced germ cell tumors (GCT): Results at the end of first stage

A. Necchi, L. Mariani, D. Raggi, P. Giannatempo, M. Colecchia, G. Calareso, R. Salvioni, Siraj M. Ali, Jon H. Chung · 2018 · Clinical Trials · DOI

Full title: Abstract CT102: APACHE: An open label, randomized, phase II study of Durvalumab (Durva), alone or in combination with Tremelimumab (Treme), in patients (pts) with advanced germ cell tumors (GCT): Results at the end of first stage

Authors: A. Necchi, L. Mariani, D. Raggi, P. Giannatempo, M. Colecchia, G. Calareso, R. Salvioni, Siraj M. Ali, Jon H. Chung

Year: 2018

Venue: Clinical Trials

DOI: https://doi.org/10.1158/1538-7445.am2018-ct102

Paper Combination immunotherapy in metastatic urothelial cancer: time for the next step?

Economopoulou, Panagiota, Bamias, Aristotelis · 2020 · Chinese clinical oncology · DOI

Full title: Combination immunotherapy in metastatic urothelial cancer: time for the next step?

Authors: Economopoulou, Panagiota, Bamias, Aristotelis

Year: 2020

Venue: Chinese clinical oncology

DOI: https://doi.org/10.21037/cco.2019.10.07

Paper A Meta-Analysis of Efficacy and Safety of PD-1/PD-L1 Inhibitors in Triple-Negative Breast Cancer.

Wang, Chaoyang · 2022 · Journal of oncology · DOI

Full title: A Meta-Analysis of Efficacy and Safety of PD-1/PD-L1 Inhibitors in Triple-Negative Breast Cancer.

Authors: Wang, Chaoyang

Year: 2022

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2022/2407211

Paper [Dermatologic toxicities of immune checkpoint inhibitors].

Sibaud, V, Boulinguez, S, Pagès, C, Riffaud, L, Lamant, L, Chira, C, Boyrie, S, Vigarios, E, Tournier, E, Meyer, N · 2018 · Annales de dermatologie et de venereologie · DOI

Full title: [Dermatologic toxicities of immune checkpoint inhibitors].

Authors: Sibaud, V, Boulinguez, S, Pagès, C, Riffaud, L, Lamant, L, Chira, C, Boyrie, S, Vigarios, E, Tournier, E, Meyer, N

Year: 2018

Venue: Annales de dermatologie et de venereologie

DOI: https://doi.org/10.1016/j.annder.2018.01.047

Paper Bronchiolitis obliterans after combination immunotherapy with pembrolizumab and ipilimumab

Amulya Balagani, M. Arain, A. Sheshadri · 2018 · Journal of Immunotherapy and Precision Oncology · DOI

Full title: Bronchiolitis obliterans after combination immunotherapy with pembrolizumab and ipilimumab

Authors: Amulya Balagani, M. Arain, A. Sheshadri

Year: 2018

Venue: Journal of Immunotherapy and Precision Oncology

DOI: https://doi.org/10.4103/jipo.jipo_8_18

Paper Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.

Foy, Susan P, Mandl, Stefanie J, dela Cruz, Tracy, Cote, Joseph J, Gordon, Evan J, Trent, Erica, Delcayre, Alain, Breitmeyer, James, Franzusoff, Alex, Rountree, Ryan B · 2016 · Cancer immunology, immunotherapy : CII · DOI

Full title: Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.

Authors: Foy, Susan P, Mandl, Stefanie J, dela Cruz, Tracy, Cote, Joseph J, Gordon, Evan J, Trent, Erica, Delcayre, Alain, Breitmeyer, James, Franzusoff, Alex, Rountree, Ryan B

Year: 2016

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-016-1816-7

Paper Radiotherapy for Melanoma: More than DNA Damage.

Rogers, Susanne J, Puric, Emsad, Eberle, Brigitte, Datta, Niloy R, Bodis, Stephan B · 2019 · Dermatology research and practice · DOI

Full title: Radiotherapy for Melanoma: More than DNA Damage.

Authors: Rogers, Susanne J, Puric, Emsad, Eberle, Brigitte, Datta, Niloy R, Bodis, Stephan B

Year: 2019

Venue: Dermatology research and practice

DOI: https://doi.org/10.1155/2019/9435389

Paper Current Therapy for Metastatic Head and Neck Cancer: Evidence, Opportunities, and Challenges

Wise‐Draper, Trisha M., Bahig, Houda, Tonneau, Marion, Karivedu, Vidhya, Burtness, Barbara · 2022 · American Society of Clinical Oncology Educational Book · DOI

Full title: Current Therapy for Metastatic Head and Neck Cancer: Evidence, Opportunities, and Challenges

Authors: Wise‐Draper, Trisha M., Bahig, Houda, Tonneau, Marion, Karivedu, Vidhya, Burtness, Barbara

Year: 2022

Venue: American Society of Clinical Oncology Educational Book

DOI: https://doi.org/10.1200/edbk_350442

Paper Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies

Sanmamed, Miguel F., Chester, C. Susan, Melero, Ignacio, Kohrt, Holbrook E. · 2016 · Annals of Oncology · DOI

Full title: Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies

Authors: Sanmamed, Miguel F., Chester, C. Susan, Melero, Ignacio, Kohrt, Holbrook E.

Year: 2016

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdw041

Paper Interleukin-33 in the Regulation of Autophagy and Apoptosis in Macrophages During Infection.

Palabiyik, Ahmet Alperen, Palabiyik, Esra · 2025 · Immunological investigations · DOI

Full title: Interleukin-33 in the Regulation of Autophagy and Apoptosis in Macrophages During Infection.

Authors: Palabiyik, Ahmet Alperen, Palabiyik, Esra

Year: 2025

Venue: Immunological investigations

DOI: https://doi.org/10.1080/08820139.2025.2547691

Paper Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma.

Qin, Yixiao, Zheng, Xiwang, Gao, Wei, Wang, Binquan, Wu, Yongyan · 2021 · Molecular therapy oncolytics · DOI

Full title: Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma.

Authors: Qin, Yixiao, Zheng, Xiwang, Gao, Wei, Wang, Binquan, Wu, Yongyan

Year: 2021

Venue: Molecular therapy oncolytics

DOI: https://doi.org/10.1016/j.omto.2021.01.011

Paper Selective activation of pro-anti-CTLA-4 antibody maintains therapeutic efficacy and reduces immune-related adverse events.

Huang, Bo-Cheng, Hong, Shih-Ting, Liao, Tzu-Yi, Ho, Kai-Wen, Liao, Jun-Min, Hsieh, Yuan-Chin, Cheng, Yi-An, Liu, En-Shuo, Li, Chia-Ching, Li, Pin-Jie, Chen, Fang-Ming, Chen, Chiao-Yun, Cheng, Tian-Lu, Huang, Ming-Yii, Chuang, Chih-Hung · 2026 · International journal of biological macromolecules · DOI

Full title: Selective activation of pro-anti-CTLA-4 antibody maintains therapeutic efficacy and reduces immune-related adverse events.

Authors: Huang, Bo-Cheng, Hong, Shih-Ting, Liao, Tzu-Yi, Ho, Kai-Wen, Liao, Jun-Min, Hsieh, Yuan-Chin, Cheng, Yi-An, Liu, En-Shuo, Li, Chia-Ching, Li, Pin-Jie, Chen, Fang-Ming, Chen, Chiao-Yun, Cheng, Tian-Lu, Huang, Ming-Yii, Chuang, Chih-Hung

Year: 2026

Venue: International journal of biological macromolecules

DOI: https://doi.org/10.1016/j.ijbiomac.2026.151096

Paper Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

Herber, Donna L., Nagaraj, Srinivas, Djeu, Julie Y., Gabrilovich, Dmitry I. · 2007 · Cancer Research · DOI

Full title: Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

Authors: Herber, Donna L., Nagaraj, Srinivas, Djeu, Julie Y., Gabrilovich, Dmitry I.

Year: 2007

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-07-0897

Paper Advances in treatment of metastatic renal cell carcinoma.

Gong, Jun, Gerendash, Benjamin, Dizman, Nazli, Khan, Abrar, Pal, Sumanta K · 2016 · Current opinion in urology · DOI

Full title: Advances in treatment of metastatic renal cell carcinoma.

Authors: Gong, Jun, Gerendash, Benjamin, Dizman, Nazli, Khan, Abrar, Pal, Sumanta K

Year: 2016

Venue: Current opinion in urology

DOI: https://doi.org/10.1097/MOU.0000000000000319

Paper Immune checkpoint inhibition: therapeutic implications in epithelial ovarian cancer.

Longoria, Teresa C, Eskander, Ramez N · 2015 · Recent patents on anti-cancer drug discovery · DOI

Full title: Immune checkpoint inhibition: therapeutic implications in epithelial ovarian cancer.

Authors: Longoria, Teresa C, Eskander, Ramez N

Year: 2015

Venue: Recent patents on anti-cancer drug discovery

DOI: https://doi.org/10.2174/1574892810666150504121000

Paper Benefits of combination therapy with immune checkpoint inhibitors and predictive role of tumour mutation burden in hepatocellular carcinoma: A systematic review and meta-analysis.

Zheng, Jiaxi, Shao, Minghai, Yang, Weifang, Ren, Justin, Chen, Xiaofeng, Yang, Haihua · 2022 · International immunopharmacology · DOI

Full title: Benefits of combination therapy with immune checkpoint inhibitors and predictive role of tumour mutation burden in hepatocellular carcinoma: A systematic review and meta-analysis.

Authors: Zheng, Jiaxi, Shao, Minghai, Yang, Weifang, Ren, Justin, Chen, Xiaofeng, Yang, Haihua

Year: 2022

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2022.109244

Paper Systemic treatments for metastatic cutaneous melanoma

Pasquali, Sandro, Hadjinicolaou, Andreas V., Chiarion‐Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone · 2018 · Cochrane Database of Systematic Reviews · DOI

Full title: Systemic treatments for metastatic cutaneous melanoma

Authors: Pasquali, Sandro, Hadjinicolaou, Andreas V., Chiarion‐Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone

Year: 2018

Venue: Cochrane Database of Systematic Reviews

DOI: https://doi.org/10.1002/14651858.cd011123.pub2

Paper Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma

Novaes, Jose A. Monteiro de Oliveira, Hirz, Taghreed, Guijarro, Irene, Nilsson, Monique B., Pisegna, Marlese A., Poteete, Alissa, Barsoumian, Hampartsoum B., Fradette, Jared J., Chen, Limo N., Gibbons, Don L., Tian, Xiangjun, Wang, Jing, Myers, Jeffrey N., McArthur, Mark J., Bell, Diana, William, William N., Heymach, John V. · 2020 · Cancer Prevention Research · DOI

Full title: Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma

Authors: Novaes, Jose A. Monteiro de Oliveira, Hirz, Taghreed, Guijarro, Irene, Nilsson, Monique B., Pisegna, Marlese A., Poteete, Alissa, Barsoumian, Hampartsoum B., Fradette, Jared J., Chen, Limo N., Gibbons, Don L., Tian, Xiangjun, Wang, Jing, Myers, Jeffrey N., McArthur, Mark J., Bell, Diana, William, William N., Heymach, John V.

Year: 2020

Venue: Cancer Prevention Research

DOI: https://doi.org/10.1158/1940-6207.capr-20-0418

Paper Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity

Zhang, Zhen, Rafei‐Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, R., Huzly, Daniela, Pinato, David J., Thimme, Robert, Meiß, Frank, Bengsch, Bertram · 2022 · Research Square (Research Square) · DOI

Full title: Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity

Authors: Zhang, Zhen, Rafei‐Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, R., Huzly, Daniela, Pinato, David J., Thimme, Robert, Meiß, Frank, Bengsch, Bertram

Year: 2022

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-2138511/v1

Paper Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

Serra-Bellver, Patricio, Versluis, Judith M, Oberoi, Honey K, Zhou, Cong, Slattery, Timothy D, Khan, Yasir, Patrinely, James R, Pires da Silva, Inês, Martínez-Vila, C, Cook, Natalie, Graham, Donna M, Carlino, Matteo S, Menzies, Alexander M, Arance, Ana M, Johnson, Douglas B, Long, Georgina V, Pickering, Lisa, Larkin, James M G, Blank, Christian U, Lorigan, Paul · 2022 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

Authors: Serra-Bellver, Patricio, Versluis, Judith M, Oberoi, Honey K, Zhou, Cong, Slattery, Timothy D, Khan, Yasir, Patrinely, James R, Pires da Silva, Inês, Martínez-Vila, C, Cook, Natalie, Graham, Donna M, Carlino, Matteo S, Menzies, Alexander M, Arance, Ana M, Johnson, Douglas B, Long, Georgina V, Pickering, Lisa, Larkin, James M G, Blank, Christian U, Lorigan, Paul

Year: 2022

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2022.09.004

Paper Immune checkpoint inhibitors for metastatic bladder cancer.

Massari, Francesco, Di Nunno, Vincenzo, Cubelli, Marta, Santoni, Matteo, Fiorentino, Michelangelo, Montironi, Rodolfo, Cheng, Liang, Lopez-Beltran, Anto, Battelli, Nicola, Ardizzoni, Andrea · 2018 · Cancer treatment reviews · DOI

Full title: Immune checkpoint inhibitors for metastatic bladder cancer.

Authors: Massari, Francesco, Di Nunno, Vincenzo, Cubelli, Marta, Santoni, Matteo, Fiorentino, Michelangelo, Montironi, Rodolfo, Cheng, Liang, Lopez-Beltran, Anto, Battelli, Nicola, Ardizzoni, Andrea

Year: 2018

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2017.12.007

Paper Combination Immunotherapy for Melanoma.

Kaufman, Howard L · 2015 · JAMA oncology · DOI

Full title: Combination Immunotherapy for Melanoma.

Authors: Kaufman, Howard L

Year: 2015

Venue: JAMA oncology

DOI: https://doi.org/10.1001/jamaoncol.2015.0479

Paper Complete response of hereditary leiomyomatosis and renal cell cancer (HLRCC)-associated renal cell carcinoma to nivolumab and ipilimumab combination immunotherapy by: a case report.

Iribe, Yasuhiro, Furuya, Mitsuko, Shibata, Yousuke, Yasui, Masato, Funahashi, Makoto, Ota, Junichi, Iwashita, Hiromichi, Nagashima, Yoji, Hasumi, Hisashi, Hayashi, Narihiko, Makiyama, Kazuhide, Kondo, Keiichi, Tanaka, Reiko, Yao, Masahiro, Nakaigawa, Noboru · 2021 · Familial cancer · DOI

Full title: Complete response of hereditary leiomyomatosis and renal cell cancer (HLRCC)-associated renal cell carcinoma to nivolumab and ipilimumab combination immunotherapy by: a case report.

Authors: Iribe, Yasuhiro, Furuya, Mitsuko, Shibata, Yousuke, Yasui, Masato, Funahashi, Makoto, Ota, Junichi, Iwashita, Hiromichi, Nagashima, Yoji, Hasumi, Hisashi, Hayashi, Narihiko, Makiyama, Kazuhide, Kondo, Keiichi, Tanaka, Reiko, Yao, Masahiro, Nakaigawa, Noboru

Year: 2021

Venue: Familial cancer

DOI: https://doi.org/10.1007/s10689-020-00195-0

Paper Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.

Boutros, Celine, Tarhini, Ahmad, Routier, Emilie, Lambotte, Olivier, Ladurie, Francois Leroy, Carbonnel, Franck, Izzeddine, Hassane, Marabelle, Aurelien, Champiat, Stephane, Berdelou, Armandine, Lanoy, Emilie, Texier, Matthieu, Libenciuc, Cristina, Eggermont, Alexander M M, Soria, Jean-Charles, Mateus, Christine, Robert, Caroline · 2016 · Nature reviews. Clinical oncology · DOI

Full title: Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.

Authors: Boutros, Celine, Tarhini, Ahmad, Routier, Emilie, Lambotte, Olivier, Ladurie, Francois Leroy, Carbonnel, Franck, Izzeddine, Hassane, Marabelle, Aurelien, Champiat, Stephane, Berdelou, Armandine, Lanoy, Emilie, Texier, Matthieu, Libenciuc, Cristina, Eggermont, Alexander M M, Soria, Jean-Charles, Mateus, Christine, Robert, Caroline

Year: 2016

Venue: Nature reviews. Clinical oncology

DOI: https://doi.org/10.1038/nrclinonc.2016.58

Paper Intracranial administration of anti-PD-1 and anti-CTLA-4 immune checkpoint-blocking monoclonal antibodies in patients with recurrent high-grade glioma.

Duerinck, Johnny, Lescrauwaet, Louise, Dirven, Iris, Del'haye, Jacomi, Stevens, Latoya, Geeraerts, Xenia, Vaeyens, Freya, Geens, Wietse, Brock, Stefanie, Vanbinst, Anne-Marie, Everaert, Hendrik, Caljon, Ben, Bruneau, Michaël, Lebrun, Laetitia, Salmon, Isabelle, Kockx, Marc, Tuyaerts, Sandra, Neyns, Bart · 2024 · Neuro-oncology · DOI

Full title: Intracranial administration of anti-PD-1 and anti-CTLA-4 immune checkpoint-blocking monoclonal antibodies in patients with recurrent high-grade glioma.

Authors: Duerinck, Johnny, Lescrauwaet, Louise, Dirven, Iris, Del'haye, Jacomi, Stevens, Latoya, Geeraerts, Xenia, Vaeyens, Freya, Geens, Wietse, Brock, Stefanie, Vanbinst, Anne-Marie, Everaert, Hendrik, Caljon, Ben, Bruneau, Michaël, Lebrun, Laetitia, Salmon, Isabelle, Kockx, Marc, Tuyaerts, Sandra, Neyns, Bart

Year: 2024

Venue: Neuro-oncology

DOI: https://doi.org/10.1093/neuonc/noae177

Paper A combination of PD-1 and TIGIT immune checkpoint inhibitors elicits a strong anti-tumour response in mesothelioma.

Shi, Huaikai, Yu, Ta-Kun, Johnson, Ben, Selvamani, Sakthi Priya, Zhuang, Ling, Lee, Kenneth, Klebe, Sonja, Smith, Samuel, Wong, Kirby, Chen, Kate, Clark, Georgina, Rath, Emma M, Pearson, Holly, Ortega, David Gallego, Linton, Anthony, Kao, Steven, Silveira, Pablo, Cheng, Yuen Yee · 2025 · Journal of experimental & clinical cancer research : CR · DOI

Full title: A combination of PD-1 and TIGIT immune checkpoint inhibitors elicits a strong anti-tumour response in mesothelioma.

Authors: Shi, Huaikai, Yu, Ta-Kun, Johnson, Ben, Selvamani, Sakthi Priya, Zhuang, Ling, Lee, Kenneth, Klebe, Sonja, Smith, Samuel, Wong, Kirby, Chen, Kate, Clark, Georgina, Rath, Emma M, Pearson, Holly, Ortega, David Gallego, Linton, Anthony, Kao, Steven, Silveira, Pablo, Cheng, Yuen Yee

Year: 2025

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-025-03314-w

Paper The evolving role of monoclonal antibodies in the treatment of patients with advanced renal cell carcinoma: a systematic review.

Di Lorenzo, Giuseppe, De Placido, Sabino, Pagliuca, Martina, Ferro, Matteo, Lucarelli, Giuseppe, Rossetti, Sabrina, Bosso, Davide, Puglia, Livio, Pignataro, Piero, Ascione, Ilaria, De Cobelli, Ottavio, Caraglia, Michele, Aieta, Michele, Terracciano, Daniela, Facchini, Gaetano, Buonerba, Carlo, Sonpavde, Guru · 2016 · Expert opinion on biological therapy · DOI

Full title: The evolving role of monoclonal antibodies in the treatment of patients with advanced renal cell carcinoma: a systematic review.

Authors: Di Lorenzo, Giuseppe, De Placido, Sabino, Pagliuca, Martina, Ferro, Matteo, Lucarelli, Giuseppe, Rossetti, Sabrina, Bosso, Davide, Puglia, Livio, Pignataro, Piero, Ascione, Ilaria, De Cobelli, Ottavio, Caraglia, Michele, Aieta, Michele, Terracciano, Daniela, Facchini, Gaetano, Buonerba, Carlo, Sonpavde, Guru

Year: 2016

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2016.1216964

Paper Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Leun, Anne M. van der, Traets, Joleen J.H., Vos, Joris L., Elbers, Joris B.W., Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S., Haanen, John B.A.G., Schumacher, Ton N., Zuur, Charlotte L. · 2023 · Cancer Research · DOI

Full title: Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Authors: Leun, Anne M. van der, Traets, Joleen J.H., Vos, Joris L., Elbers, Joris B.W., Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S., Haanen, John B.A.G., Schumacher, Ton N., Zuur, Charlotte L.

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-2281

Paper Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

P. Serra-Bellver, J. Versluis, H. Oberoi, Cong Zhou, T. Slattery, Y. Khan, J. Patrinely, I. Pires da Silva, C. Martinez-Vila, N. Cook, D. Graham, M. Carlino, A. Menzies, A. Arance, Douglas B. Douglas, G. Long, L. Pickering, J. Larkin, C. Blank, P. Lorigan · 2022 · European Journal of Cancer · DOI

Full title: Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

Authors: P. Serra-Bellver, J. Versluis, H. Oberoi, Cong Zhou, T. Slattery, Y. Khan, J. Patrinely, I. Pires da Silva, C. Martinez-Vila, N. Cook, D. Graham, M. Carlino, A. Menzies, A. Arance, Douglas B. Douglas, G. Long, L. Pickering, J. Larkin, C. Blank, P. Lorigan

Year: 2022

Venue: European Journal of Cancer

DOI: https://doi.org/10.2139/ssrn.4066218

Paper Anti-CTLA4 Therapy Leads to Early Expansion of a Peripheral Th17 Population and Induction of Th1 Cytokines.

Nakazawa, Mari, Charmsaz, Soren, Hallab, Elsa, Fang, Mike, Kao, Chester, Brancati, Madelena, Munjal, Kabeer, Li, Howard L, Leatherman, James M, Griffin, Ervin, Thoburn, Christopher J, Lipson, Evan J, Ged, Yasser, Hoffman-Censits, Jean, Baretti, Marina, Tang, Laura, Bansal, Sanjay, Garonce-Hediger, Rachel, Guha, Aditi, Chandler, G Scott, Mohindra, Rajat, Jaffee, Elizabeth M, Ho, Won Jin, Yarchoan, Mark · 2025 · Cancer immunology research · DOI

Full title: Anti-CTLA4 Therapy Leads to Early Expansion of a Peripheral Th17 Population and Induction of Th1 Cytokines.

Authors: Nakazawa, Mari, Charmsaz, Soren, Hallab, Elsa, Fang, Mike, Kao, Chester, Brancati, Madelena, Munjal, Kabeer, Li, Howard L, Leatherman, James M, Griffin, Ervin, Thoburn, Christopher J, Lipson, Evan J, Ged, Yasser, Hoffman-Censits, Jean, Baretti, Marina, Tang, Laura, Bansal, Sanjay, Garonce-Hediger, Rachel, Guha, Aditi, Chandler, G Scott, Mohindra, Rajat, Jaffee, Elizabeth M, Ho, Won Jin, Yarchoan, Mark

Year: 2025

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-24-1055

Paper Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal liver metastases.

Keenan, Bridget P, Qiao, Guilin, Kunda, Nicholas, Kone, Lyonell, Guldberg, Sophia M, Todeschini, Letizia, Kumar, Prabhakaran, Pollini, Tommaso, Hernandez, Sophia, Qin, Jianzhong, Fong, Lawrence, Spitzer, Matthew H, Prabhakar, Bellur S, Maker, Ajay V · 2025 · Science advances · DOI

Full title: Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal liver metastases.

Authors: Keenan, Bridget P, Qiao, Guilin, Kunda, Nicholas, Kone, Lyonell, Guldberg, Sophia M, Todeschini, Letizia, Kumar, Prabhakaran, Pollini, Tommaso, Hernandez, Sophia, Qin, Jianzhong, Fong, Lawrence, Spitzer, Matthew H, Prabhakar, Bellur S, Maker, Ajay V

Year: 2025

Venue: Science advances

DOI: https://doi.org/10.1126/sciadv.adv9161

Paper The immunocytokine L19-IL2 eradicates cancer when used in combination with CTLA-4 blockade or with L19-TNF.

Schwager, Kathrin, Hemmerle, Teresa, Aebischer, David, Neri, Dario · 2013 · The Journal of investigative dermatology · DOI

Full title: The immunocytokine L19-IL2 eradicates cancer when used in combination with CTLA-4 blockade or with L19-TNF.

Authors: Schwager, Kathrin, Hemmerle, Teresa, Aebischer, David, Neri, Dario

Year: 2013

Venue: The Journal of investigative dermatology

DOI: https://doi.org/10.1038/jid.2012.376

Paper Prolonging Survival: The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive-Stage Small Cell Lung Cancer.

Melosky, Barbara, Cheema, Parneet K, Brade, Anthony, McLeod, Deanna, Liu, Geoffrey, Price, Paul Wheatley, Jao, Kevin, Schellenberg, Devin D, Juergens, Rosalyn, Leighl, Natasha, Chu, Quincy · 2020 · The oncologist · DOI

Full title: Prolonging Survival: The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive-Stage Small Cell Lung Cancer.

Authors: Melosky, Barbara, Cheema, Parneet K, Brade, Anthony, McLeod, Deanna, Liu, Geoffrey, Price, Paul Wheatley, Jao, Kevin, Schellenberg, Devin D, Juergens, Rosalyn, Leighl, Natasha, Chu, Quincy

Year: 2020

Venue: The oncologist

DOI: https://doi.org/10.1634/theoncologist.2020-0193

Paper Immune Checkpoint Inhibitors for Patients Aged ≥ 75 Years with Advanced Cancer in First- and Second-Line Settings: A Meta-Analysis.

Landre, Thierry, Des Guetz, Gaetan, Chouahnia, Kader, Fossey-Diaz, Virginie, Culine, Stéphane · 2020 · Drugs & aging · DOI

Full title: Immune Checkpoint Inhibitors for Patients Aged ≥ 75 Years with Advanced Cancer in First- and Second-Line Settings: A Meta-Analysis.

Authors: Landre, Thierry, Des Guetz, Gaetan, Chouahnia, Kader, Fossey-Diaz, Virginie, Culine, Stéphane

Year: 2020

Venue: Drugs & aging

DOI: https://doi.org/10.1007/s40266-020-00788-5

Paper Of Mice and Not Men: Differences between Mouse and Human Immunology

Mestas, Javier, Hughes, Christopher C.W. · 2004 · The Journal of Immunology · DOI

Full title: Of Mice and Not Men: Differences between Mouse and Human Immunology

Authors: Mestas, Javier, Hughes, Christopher C.W.

Year: 2004

Venue: The Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.172.5.2731

Paper [Immune checkpoint‑targeted cancer immunotherapies].

Swatler, Julian, Kozłowska, Ewa · 2016 · Postepy higieny i medycyny doswiadczalnej (Online) · DOI

Full title: [Immune checkpoint‑targeted cancer immunotherapies].

Authors: Swatler, Julian, Kozłowska, Ewa

Year: 2016

Venue: Postepy higieny i medycyny doswiadczalnej (Online)

DOI: https://doi.org/10.5604/17322693.1192926

Paper Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers.

Medjebar, Soleine, Truntzer, Caroline, Perrichet, Anaïs, Limagne, Emeric, Fumet, Jean-David, Richard, Corentin, Elkrief, Arielle, Routy, Bertrand, Rébé, Cédric, Ghiringhelli, François · 2020 · Oncoimmunology · DOI

Full title: Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers.

Authors: Medjebar, Soleine, Truntzer, Caroline, Perrichet, Anaïs, Limagne, Emeric, Fumet, Jean-David, Richard, Corentin, Elkrief, Arielle, Routy, Bertrand, Rébé, Cédric, Ghiringhelli, François

Year: 2020

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2020.1836766

Paper Targeting immune checkpoints in unresectable metastatic cutaneous melanoma: a systematic review and meta-analysis of anti-CTLA-4 and anti-PD-1 agents trials.

Yun, Seongseok, Vincelette, Nicole D, Green, Myke R, Wahner Hendrickson, Andrea E, Abraham, Ivo · 2016 · Cancer medicine · DOI

Full title: Targeting immune checkpoints in unresectable metastatic cutaneous melanoma: a systematic review and meta-analysis of anti-CTLA-4 and anti-PD-1 agents trials.

Authors: Yun, Seongseok, Vincelette, Nicole D, Green, Myke R, Wahner Hendrickson, Andrea E, Abraham, Ivo

Year: 2016

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.732

Paper Oncolytic vaccinia virus expressing non-secreted decoy-resistant IL-18 mutein elicits potent antitumor effects with enhanced safety.

Ye, Junjie, Chen, Lingjuan, Patel, Sefali, Ming, Pingpo, Li, Chunyan, Waltermire, Julia, Zhao, Jinshun, Ren, Jinghua, Bartlett, David L, Liu, Zuqiang · 2025 · Molecular therapy. Oncology · DOI

Full title: Oncolytic vaccinia virus expressing non-secreted decoy-resistant IL-18 mutein elicits potent antitumor effects with enhanced safety.

Authors: Ye, Junjie, Chen, Lingjuan, Patel, Sefali, Ming, Pingpo, Li, Chunyan, Waltermire, Julia, Zhao, Jinshun, Ren, Jinghua, Bartlett, David L, Liu, Zuqiang

Year: 2025

Venue: Molecular therapy. Oncology

DOI: https://doi.org/10.1016/j.omton.2025.201022

Paper Unleashing the Power of immune Checkpoints: A new strategy for enhancing Treg cells depletion to boost antitumor immunity.

Li, Guoxin, Li, Siqi, Jiang, Yilin, Chen, Tao, An, Zhengwen · 2025 · International immunopharmacology · DOI

Full title: Unleashing the Power of immune Checkpoints: A new strategy for enhancing Treg cells depletion to boost antitumor immunity.

Authors: Li, Guoxin, Li, Siqi, Jiang, Yilin, Chen, Tao, An, Zhengwen

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2024.113952

Paper Non-small cell lung cancer with MET exon 14 skipping alteration responding to immunotherapy: a case report.

Chen, Zhuxing, Zhu, Feng, Li, Caichen, Li, Jianfu, Cheng, Bo, Xiong, Shan, Zhong, Ran, Liang, Wenhua, He, Jianxing · 2021 · Annals of translational medicine · DOI

Full title: Non-small cell lung cancer with MET exon 14 skipping alteration responding to immunotherapy: a case report.

Authors: Chen, Zhuxing, Zhu, Feng, Li, Caichen, Li, Jianfu, Cheng, Bo, Xiong, Shan, Zhong, Ran, Liang, Wenhua, He, Jianxing

Year: 2021

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm-20-6829

Paper Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature.

Martinez, Mariela, Kotamarti, Srinath, Schulman, Ariel, Mooppan, Unni, Wang, Jen · 2022 · Urology case reports · DOI

Full title: Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature.

Authors: Martinez, Mariela, Kotamarti, Srinath, Schulman, Ariel, Mooppan, Unni, Wang, Jen

Year: 2022

Venue: Urology case reports

DOI: https://doi.org/10.1016/j.eucr.2021.101835

Paper Immunotherapies in Early and Advanced Renal Cell Cancer.

Kasenda, Benjamin, Larkin, James, Gore, Martin · 2015 · Progress in tumor research · DOI

Full title: Immunotherapies in Early and Advanced Renal Cell Cancer.

Authors: Kasenda, Benjamin, Larkin, James, Gore, Martin

Year: 2015

Venue: Progress in tumor research

DOI: https://doi.org/10.1159/000436988

Paper Drug discovery targeting p21-activated kinase 4 (PAK4): a patent review.

Wang, Hanxun, Song, Peilu, Gao, Yinli, Shen, Lanlan, Xu, Hanqin, Wang, Jian, Cheng, Maosheng · 2021 · Expert opinion on therapeutic patents · DOI

Full title: Drug discovery targeting p21-activated kinase 4 (PAK4): a patent review.

Authors: Wang, Hanxun, Song, Peilu, Gao, Yinli, Shen, Lanlan, Xu, Hanqin, Wang, Jian, Cheng, Maosheng

Year: 2021

Venue: Expert opinion on therapeutic patents

DOI: https://doi.org/10.1080/13543776.2021.1944100

Paper Abstract 2778: Mapping the extracellular pH gradient of colorectal cancer after immuno-thermal ablation

Slovak, Ryan, Coman, Daniel, Ludwig, Johannes, Kim, Hyun S. · 2020 · Cancer Research · DOI

Full title: Abstract 2778: Mapping the extracellular pH gradient of colorectal cancer after immuno-thermal ablation

Authors: Slovak, Ryan, Coman, Daniel, Ludwig, Johannes, Kim, Hyun S.

Year: 2020

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2020-2778

Paper Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective.

Walia, Harleen Kaur, Sharma, Parul, Singh, Navneet, Sharma, Siddharth · 2022 · Current treatment options in oncology · DOI

Full title: Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective.

Authors: Walia, Harleen Kaur, Sharma, Parul, Singh, Navneet, Sharma, Siddharth

Year: 2022

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-022-00949-1

Paper Combination therapy of immunocytokines with ipilimumab: a cure for melanoma?

Wang, Tao, Somasundaram, Rajasekharan, Herlyn, Meenhard · 2013 · The Journal of investigative dermatology · DOI

Full title: Combination therapy of immunocytokines with ipilimumab: a cure for melanoma?

Authors: Wang, Tao, Somasundaram, Rajasekharan, Herlyn, Meenhard

Year: 2013

Venue: The Journal of investigative dermatology

DOI: https://doi.org/10.1038/jid.2012.433

Paper Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.

Moynihan, Kelly D, Opel, Cary F, Szeto, Gregory L, Tzeng, Alice, Zhu, Eric F, Engreitz, Jesse M, Williams, Robert T, Rakhra, Kavya, Zhang, Michael H, Rothschilds, Adrienne M, Kumari, Sudha, Kelly, Ryan L, Kwan, Byron H, Abraham, Wuhbet, Hu, Kevin, Mehta, Naveen K, Kauke, Monique J, Suh, Heikyung, Cochran, Jennifer R, Lauffenburger, Douglas A, Wittrup, K Dane, Irvine, Darrell J · 2016 · Nature medicine · DOI

Full title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.

Authors: Moynihan, Kelly D, Opel, Cary F, Szeto, Gregory L, Tzeng, Alice, Zhu, Eric F, Engreitz, Jesse M, Williams, Robert T, Rakhra, Kavya, Zhang, Michael H, Rothschilds, Adrienne M, Kumari, Sudha, Kelly, Ryan L, Kwan, Byron H, Abraham, Wuhbet, Hu, Kevin, Mehta, Naveen K, Kauke, Monique J, Suh, Heikyung, Cochran, Jennifer R, Lauffenburger, Douglas A, Wittrup, K Dane, Irvine, Darrell J

Year: 2016

Venue: Nature medicine

DOI: https://doi.org/10.1038/nm.4200

Paper A novel bispecific nanobody with PD-L1/TIGIT dual immune checkpoint blockade.

Ma, Linlin, Gai, Junwei, Qiao, Peng, Li, Yanfei, Li, Xiaofei, Zhu, Min, Li, Guanghui, Wan, Yakun · 2020 · Biochemical and biophysical research communications · DOI

Full title: A novel bispecific nanobody with PD-L1/TIGIT dual immune checkpoint blockade.

Authors: Ma, Linlin, Gai, Junwei, Qiao, Peng, Li, Yanfei, Li, Xiaofei, Zhu, Min, Li, Guanghui, Wan, Yakun

Year: 2020

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2020.07.072

Paper CD103 blockade impair anti-CTLA-4 immunotherapy in oral cancer.

Xiao, Yao, Mao, Liang, Yang, Qi-Chao, Wang, Shuo, Wu, Zhi-Zhong, Wan, Shu-Cheng, Zhang, Meng-Jie, Sun, Zhi-Jun · 2023 · Oral oncology · DOI

Full title: CD103 blockade impair anti-CTLA-4 immunotherapy in oral cancer.

Authors: Xiao, Yao, Mao, Liang, Yang, Qi-Chao, Wang, Shuo, Wu, Zhi-Zhong, Wan, Shu-Cheng, Zhang, Meng-Jie, Sun, Zhi-Jun

Year: 2023

Venue: Oral oncology

DOI: https://doi.org/10.1016/j.oraloncology.2023.106331

Paper Response to nivolumab combining radiotherapy and nimotuzumab in metastatic oral squamous cell carcinoma patient with strong PD-L1 expression: a case report.

Tang, Xiao, Chen, Shiqing, Sui, Qianqian, Li, Xiaoguang, Liu, Zhonglong, Zhu, Fengshuo, Ding, Jiping, Yao, Yuan, Jiang, Bin, He, Yue · 2020 · Annals of translational medicine · DOI

Full title: Response to nivolumab combining radiotherapy and nimotuzumab in metastatic oral squamous cell carcinoma patient with strong PD-L1 expression: a case report.

Authors: Tang, Xiao, Chen, Shiqing, Sui, Qianqian, Li, Xiaoguang, Liu, Zhonglong, Zhu, Fengshuo, Ding, Jiping, Yao, Yuan, Jiang, Bin, He, Yue

Year: 2020

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm.2020.02.96

Paper What’s new in melanoma? Combination!

P. Ascierto, F. Marincola, M. Atkins · 2015 · Journal of Translational Medicine · DOI

Full title: What’s new in melanoma? Combination!

Authors: P. Ascierto, F. Marincola, M. Atkins

Year: 2015

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-015-0582-1

Paper Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis.

Thomas, Molly Fisher, Slowikowski, Kamil, Manakongtreecheep, Kasidet, Sen, Pritha, Samanta, Nandini, Tantivit, Jessica, Nasrallah, Mazen, Zubiri, Leyre, Smith, Neal P, Tirard, Alice, Ramesh, Swetha, Arnold, Benjamin Y, Nieman, Linda T, Chen, Jonathan H, Eisenhaure, Thomas, Pelka, Karin, Song, Yuhui, Xu, Katherine H, Jorgji, Vjola, Pinto, Christopher J, Sharova, Tatyana, Glasser, Rachel, Chan, PuiYee, Sullivan, Ryan J, Khalili, Hamed, Juric, Dejan, Boland, Genevieve M, Dougan, Michael, Hacohen, Nir, Li, Bo, Reynolds, Kerry L, Villani, Alexandra-Chloé · 2024 · Nature medicine · DOI

Full title: Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis.

Authors: Thomas, Molly Fisher, Slowikowski, Kamil, Manakongtreecheep, Kasidet, Sen, Pritha, Samanta, Nandini, Tantivit, Jessica, Nasrallah, Mazen, Zubiri, Leyre, Smith, Neal P, Tirard, Alice, Ramesh, Swetha, Arnold, Benjamin Y, Nieman, Linda T, Chen, Jonathan H, Eisenhaure, Thomas, Pelka, Karin, Song, Yuhui, Xu, Katherine H, Jorgji, Vjola, Pinto, Christopher J, Sharova, Tatyana, Glasser, Rachel, Chan, PuiYee, Sullivan, Ryan J, Khalili, Hamed, Juric, Dejan, Boland, Genevieve M, Dougan, Michael, Hacohen, Nir, Li, Bo, Reynolds, Kerry L, Villani, Alexandra-Chloé

Year: 2024

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-024-02895-x

Paper Preclinical Evaluation and Pilot Clinical Study of CD137 PET Radiotracer for Noninvasive Monitoring Early Responses of Immunotherapy

K. Cheng, Luna Ge, Miaomiao Song, Wanhu Li, Jinsong Zheng, Jingru Liu, Yuxi Luo, Pengfei Sun, Shengnan Xu, Zhen Cheng, Jinming Yu, Jie Liu · 2024 · Journal of Nuclear Medicine · DOI

Full title: Preclinical Evaluation and Pilot Clinical Study of CD137 PET Radiotracer for Noninvasive Monitoring Early Responses of Immunotherapy

Authors: K. Cheng, Luna Ge, Miaomiao Song, Wanhu Li, Jinsong Zheng, Jingru Liu, Yuxi Luo, Pengfei Sun, Shengnan Xu, Zhen Cheng, Jinming Yu, Jie Liu

Year: 2024

Venue: Journal of Nuclear Medicine

DOI: https://doi.org/10.2967/jnumed.124.268068

Paper Tumor Regression and Cure Depends on Sustained Th1 Responses.

Dai, Min, Hellstrom, Ingegerd, Yip, Yuen Y, Sjögren, Hans Olov, Hellstrom, Karl Erik · 2018 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Tumor Regression and Cure Depends on Sustained Th1 Responses.

Authors: Dai, Min, Hellstrom, Ingegerd, Yip, Yuen Y, Sjögren, Hans Olov, Hellstrom, Karl Erik

Year: 2018

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000231

Paper The effects of checkpoint inhibition on head and neck squamous cell carcinoma: A systematic review.

Ghanizada, Mustafa, Jakobsen, Kathrine Kronberg, Grønhøj, Christian, von Buchwald, Christian · 2019 · Oral oncology · DOI

Full title: The effects of checkpoint inhibition on head and neck squamous cell carcinoma: A systematic review.

Authors: Ghanizada, Mustafa, Jakobsen, Kathrine Kronberg, Grønhøj, Christian, von Buchwald, Christian

Year: 2019

Venue: Oral oncology

DOI: https://doi.org/10.1016/j.oraloncology.2019.01.018

Paper Interpretable systems biomarkers predict response to immune-checkpoint inhibitors.

Lapuente-Santana, Óscar, van Genderen, Maisa, Hilbers, Peter A J, Finotello, Francesca, Eduati, Federica · 2021 · Patterns (New York, N.Y.) · DOI

Full title: Interpretable systems biomarkers predict response to immune-checkpoint inhibitors.

Authors: Lapuente-Santana, Óscar, van Genderen, Maisa, Hilbers, Peter A J, Finotello, Francesca, Eduati, Federica

Year: 2021

Venue: Patterns (New York, N.Y.)

DOI: https://doi.org/10.1016/j.patter.2021.100293

Paper [Immunotherapy for renal cell carcinoma - current status].

Grimm, Marc-Oliver, Foller, Susan · 2018 · Aktuelle Urologie · DOI

Full title: [Immunotherapy for renal cell carcinoma - current status].

Authors: Grimm, Marc-Oliver, Foller, Susan

Year: 2018

Venue: Aktuelle Urologie

DOI: https://doi.org/10.1055/a-0581-4451

Paper Perioperative Immune Checkpoint Blockade for Muscle-Invasive and Metastatic Bladder Cancer.

Ramamurthy, Chethan, Wheeler, Karen M, Trecarten, Shaun, Hassouneh, Zaineb, Ji, Niannian, Lee, Yifen, Svatek, Robert S, Mukherjee, Neelam · 2024 · Journal of cancer immunology · DOI

Full title: Perioperative Immune Checkpoint Blockade for Muscle-Invasive and Metastatic Bladder Cancer.

Authors: Ramamurthy, Chethan, Wheeler, Karen M, Trecarten, Shaun, Hassouneh, Zaineb, Ji, Niannian, Lee, Yifen, Svatek, Robert S, Mukherjee, Neelam

Year: 2024

Venue: Journal of cancer immunology

DOI: https://doi.org/10.33696/cancerimmunol.6.081

Paper Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable head and neck squamous cell carcinoma.

Zech, Henrike B, Moeckelmann, Nikolaus, Boettcher, Arne, Muenscher, Adrian, Binder, Mascha, Vettorazzi, Eik, Bokemeyer, Carsten, Schafhausen, Philippe, Betz, Christian S, Busch, Chia-Jung · 2020 · Future oncology (London, England) · DOI

Full title: Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable head and neck squamous cell carcinoma.

Authors: Zech, Henrike B, Moeckelmann, Nikolaus, Boettcher, Arne, Muenscher, Adrian, Binder, Mascha, Vettorazzi, Eik, Bokemeyer, Carsten, Schafhausen, Philippe, Betz, Christian S, Busch, Chia-Jung

Year: 2020

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2020-0595

Paper Patterns of immune-related adverse events (irAEs) in adolescent and young adult (AYA) patients with melanoma receiving immune checkpoint inhibitors (ICIs).

Jia He, I. John, Faraz Afridi, Mianen Sun, Yinghong Wang, Michael Roth, J. McQuade · 2024 · Journal of Clinical Oncology · DOI

Full title: Patterns of immune-related adverse events (irAEs) in adolescent and young adult (AYA) patients with melanoma receiving immune checkpoint inhibitors (ICIs).

Authors: Jia He, I. John, Faraz Afridi, Mianen Sun, Yinghong Wang, Michael Roth, J. McQuade

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.12117

Paper Clinical benefits of PD-1/PD-L1 inhibitors in advanced hepatocellular carcinoma: a systematic review and meta-analysis.

Rao, Quan, Li, Min, Xu, Wei, Pang, Kai, Guo, XiaoBo, Wang, Dong, Liu, Jun, Guo, Wei, Zhang, ZhongTao · 2020 · Hepatology international · DOI

Full title: Clinical benefits of PD-1/PD-L1 inhibitors in advanced hepatocellular carcinoma: a systematic review and meta-analysis.

Authors: Rao, Quan, Li, Min, Xu, Wei, Pang, Kai, Guo, XiaoBo, Wang, Dong, Liu, Jun, Guo, Wei, Zhang, ZhongTao

Year: 2020

Venue: Hepatology international

DOI: https://doi.org/10.1007/s12072-020-10064-8

Paper Immunotherapy in Cancer Treatment: Harnessing the Power of the Immune System

Alok Kumar, Kanchan Singh, Kartik Kumar, Sachin Kumar, Arjun Singh, Alpesh Tripath, Lakshya Tiwari · 2024 · Research Journal of Pharmaceutical Dosage Forms and Technology · DOI

Full title: Immunotherapy in Cancer Treatment: Harnessing the Power of the Immune System

Authors: Alok Kumar, Kanchan Singh, Kartik Kumar, Sachin Kumar, Arjun Singh, Alpesh Tripath, Lakshya Tiwari

Year: 2024

Venue: Research Journal of Pharmaceutical Dosage Forms and Technology

DOI: https://doi.org/10.52711/0975-4377.2024.00017

Paper Novel therapeutic agents in the management of brain metastases.

Venur, Vyshak A, Ahluwalia, Manmeet S · 2017 · Current opinion in oncology · DOI

Full title: Novel therapeutic agents in the management of brain metastases.

Authors: Venur, Vyshak A, Ahluwalia, Manmeet S

Year: 2017

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000393

Paper Thyroid Toxicity Following Immune Checkpoint Inhibitor Treatment in Advanced Cancer.

Muir, Christopher A, Menzies, Alexander M, Clifton-Bligh, Roderick, Tsang, Venessa H M · 2020 · Thyroid : official journal of the American Thyroid Association · DOI

Full title: Thyroid Toxicity Following Immune Checkpoint Inhibitor Treatment in Advanced Cancer.

Authors: Muir, Christopher A, Menzies, Alexander M, Clifton-Bligh, Roderick, Tsang, Venessa H M

Year: 2020

Venue: Thyroid : official journal of the American Thyroid Association

DOI: https://doi.org/10.1089/thy.2020.0032

Paper Immune checkpoint blockade in small cell lung cancer.

Tay, Rebecca Y, Heigener, David, Reck, Martin, Califano, Raffaele · 2019 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: Immune checkpoint blockade in small cell lung cancer.

Authors: Tay, Rebecca Y, Heigener, David, Reck, Martin, Califano, Raffaele

Year: 2019

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2019.08.024

Paper DISCERN: A Randomized Pilot Study Comparing Dual Versus Single Immune Checkpoint Blockade Plus Chemotherapy in PD-L1 Negative Advanced Non-Small Cell Lung Cancer.

Desai, Aakash, McNeeley, Ellen, Alhushki, Sanad, Haught, Mia, Masjoan Juncos, Juan Xavier, Patel, Dhartiben, Brand, Jeffery, McManus, Leigh, Bae, Sejong, Khalil, Maya, Boumber, Yanis · 2025 · Clinical lung cancer · DOI

Full title: DISCERN: A Randomized Pilot Study Comparing Dual Versus Single Immune Checkpoint Blockade Plus Chemotherapy in PD-L1 Negative Advanced Non-Small Cell Lung Cancer.

Authors: Desai, Aakash, McNeeley, Ellen, Alhushki, Sanad, Haught, Mia, Masjoan Juncos, Juan Xavier, Patel, Dhartiben, Brand, Jeffery, McManus, Leigh, Bae, Sejong, Khalil, Maya, Boumber, Yanis

Year: 2025

Venue: Clinical lung cancer

DOI: https://doi.org/10.1016/j.cllc.2025.08.013

Paper Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts.

Poh, Su Li, Linn, Yeh Ching · 2016 · Cancer immunology, immunotherapy : CII · DOI

Full title: Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts.

Authors: Poh, Su Li, Linn, Yeh Ching

Year: 2016

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-016-1815-8

Paper Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility.

Pentcheva-Hoang, Tsvetelina, Simpson, Tyler R, Montalvo-Ortiz, Welby, Allison, James P · 2014 · Cancer immunology research · DOI

Full title: Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility.

Authors: Pentcheva-Hoang, Tsvetelina, Simpson, Tyler R, Montalvo-Ortiz, Welby, Allison, James P

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0104

Paper Molecular characterization of clinical responses to PD-1/PD-L1 inhibitors in non-small cell lung cancer: Predictive value of multidimensional immunomarker detection for the efficacy of PD-1 inhibitors in Chinese patients.

Song, Peng, Cui, Xiaoxia, Bai, Li, Zhou, Xiangdong, Zhu, Xiaoli, Zhang, Jian, Jin, Faguang, Zhao, Jianping, Zhou, Chengzhi, Zhou, Yanbin, Zhang, Xiaoju, Wang, Kai, Wang, Qi, Yu, Yao, Zhang, Xiaoyu, Bai, Chunxue, Zhang, Li · 2019 · Thoracic cancer · DOI

Full title: Molecular characterization of clinical responses to PD-1/PD-L1 inhibitors in non-small cell lung cancer: Predictive value of multidimensional immunomarker detection for the efficacy of PD-1 inhibitors in Chinese patients.

Authors: Song, Peng, Cui, Xiaoxia, Bai, Li, Zhou, Xiangdong, Zhu, Xiaoli, Zhang, Jian, Jin, Faguang, Zhao, Jianping, Zhou, Chengzhi, Zhou, Yanbin, Zhang, Xiaoju, Wang, Kai, Wang, Qi, Yu, Yao, Zhang, Xiaoyu, Bai, Chunxue, Zhang, Li

Year: 2019

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.13078

Paper Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.

Redmond, William L, Linch, Stefanie N, Kasiewicz, Melissa J · 2014 · Cancer immunology research · DOI

Full title: Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.

Authors: Redmond, William L, Linch, Stefanie N, Kasiewicz, Melissa J

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0031-T

Paper Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis.

Lee, James C, Mehdizadeh, Sadaf, Smith, Jennifer, Young, Arabella, Mufazalov, Ilgiz A, Mowery, Cody T, Daud, Adil, Bluestone, Jeffrey A · 2020 · Science immunology · DOI

Full title: Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis.

Authors: Lee, James C, Mehdizadeh, Sadaf, Smith, Jennifer, Young, Arabella, Mufazalov, Ilgiz A, Mowery, Cody T, Daud, Adil, Bluestone, Jeffrey A

Year: 2020

Venue: Science immunology

DOI: https://doi.org/10.1126/sciimmunol.aba0759

Paper Programmed death receptor-1/programmed death-ligand 1 inhibitors: Clinical progress and biomarker exploration in gastric cancer.

Shi, Jin, Song, Xudong, Gao, Zihao, Dai, Dezhu, Ding, Fan, Wu, Xu, Dai, Wufei, Tao, Guoquan · 2024 · Heliyon · DOI

Full title: Programmed death receptor-1/programmed death-ligand 1 inhibitors: Clinical progress and biomarker exploration in gastric cancer.

Authors: Shi, Jin, Song, Xudong, Gao, Zihao, Dai, Dezhu, Ding, Fan, Wu, Xu, Dai, Wufei, Tao, Guoquan

Year: 2024

Venue: Heliyon

DOI: https://doi.org/10.1016/j.heliyon.2024.e38710

Paper Combinatorial approach to cancer immunotherapy: strength in numbers.

Vilgelm, Anna E, Johnson, Douglas B, Richmond, Ann · 2016 · Journal of leukocyte biology · DOI

Full title: Combinatorial approach to cancer immunotherapy: strength in numbers.

Authors: Vilgelm, Anna E, Johnson, Douglas B, Richmond, Ann

Year: 2016

Venue: Journal of leukocyte biology

DOI: https://doi.org/10.1189/jlb.5RI0116-013RR

Paper Nivolumab + relatlimab for the treatment of unresectable or metastatic melanoma.

Koseła-Paterczyk, Hanna, Rutkowski, Piotr · 2023 · Expert opinion on biological therapy · DOI

Full title: Nivolumab + relatlimab for the treatment of unresectable or metastatic melanoma.

Authors: Koseła-Paterczyk, Hanna, Rutkowski, Piotr

Year: 2023

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2023.2215922

Paper In vitro-irradiated cancer vaccine enhances anti-tumor efficacy of radiotherapy and PD-L1 blockade in a syngeneic murine breast cancer model.

Kim, Yoomin, Jeon, Seung Hyuck, Kim, Seongmin, Kang, Mi Hyun, Han, Min Guk, Lee, Se Yup, Kim, In Ah · 2024 · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · DOI

Full title: In vitro-irradiated cancer vaccine enhances anti-tumor efficacy of radiotherapy and PD-L1 blockade in a syngeneic murine breast cancer model.

Authors: Kim, Yoomin, Jeon, Seung Hyuck, Kim, Seongmin, Kang, Mi Hyun, Han, Min Guk, Lee, Se Yup, Kim, In Ah

Year: 2024

Venue: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

DOI: https://doi.org/10.1016/j.radonc.2024.110480

Paper Radiotherapy complements immune checkpoint blockade.

Ngiow, Shin Foong, McArthur, Grant A, Smyth, Mark J · 2015 · Cancer cell · DOI

Full title: Radiotherapy complements immune checkpoint blockade.

Authors: Ngiow, Shin Foong, McArthur, Grant A, Smyth, Mark J

Year: 2015

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2015.03.015

Paper Abstract B058: VEGF inhibition enhances immune checkpoint blockade efficacy in ovarian cancer

Nakkina, Sai Preethi, Medvedev, Sergey, Ma, Kai, Anderson, Matthew, Simpkins, Fiona, Powell, Daniel J., Gitto, Sarah B. · 2025 · Cancer Research · DOI

Full title: Abstract B058: VEGF inhibition enhances immune checkpoint blockade efficacy in ovarian cancer

Authors: Nakkina, Sai Preethi, Medvedev, Sergey, Ma, Kai, Anderson, Matthew, Simpkins, Fiona, Powell, Daniel J., Gitto, Sarah B.

Year: 2025

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.ovarian25-b058

Paper Efficacy of Tumor Vaccines and Cellular Immunotherapies in Non–Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis

Dammeijer, Floris, Lievense, Lysanne A., Veerman, G., Hoogsteden, Henk C., Hegmans, Joost P., Arends, Lidia R., Aerts, Joachim G.J.V. · 2016 · Journal of Clinical Oncology · DOI

Full title: Efficacy of Tumor Vaccines and Cellular Immunotherapies in Non–Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis

Authors: Dammeijer, Floris, Lievense, Lysanne A., Veerman, G., Hoogsteden, Henk C., Hegmans, Joost P., Arends, Lidia R., Aerts, Joachim G.J.V.

Year: 2016

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2015.66.3955

Paper Response to the rechallenge of combination immunotherapy in a patient with late-stage gastric cancer: case report.

Zhang, Zhening, Cheng, Siyuan, Qi, Changsong, Zhang, Xiaotian, Peng, Zhi, Shen, Lin · 2022 · Annals of palliative medicine · DOI

Full title: Response to the rechallenge of combination immunotherapy in a patient with late-stage gastric cancer: case report.

Authors: Zhang, Zhening, Cheng, Siyuan, Qi, Changsong, Zhang, Xiaotian, Peng, Zhi, Shen, Lin

Year: 2022

Venue: Annals of palliative medicine

DOI: https://doi.org/10.21037/apm-21-83

Paper [Immunocheckpoint inhibition in head and neck squamous cell carcinoma: the current status and progress].

Huang, L L, Shi, Y K · 2019 · Zhonghua zhong liu za zhi [Chinese journal of oncology] · DOI

Full title: [Immunocheckpoint inhibition in head and neck squamous cell carcinoma: the current status and progress].

Authors: Huang, L L, Shi, Y K

Year: 2019

Venue: Zhonghua zhong liu za zhi [Chinese journal of oncology]

DOI: https://doi.org/10.3760/cma.j.issn.0253-3766.2019.09.001

Paper Overall survival after isolated hepatic perfusion in combination with ipilimumab and nivolumab in patients with uveal melanoma metastases (the SCANDIUM II trial).

A. Nelson, A. Shafazand, C. Cahlin, A. Carneiro, H. Helgadottir, M. Levin, M. Rizell, G. Ullenhag, S. Wirén, P. Lindnér, J. Nilsson, L. Ny, R. Olofsson Bagge · 2024 · Journal of Clinical Oncology · DOI

Full title: Overall survival after isolated hepatic perfusion in combination with ipilimumab and nivolumab in patients with uveal melanoma metastases (the SCANDIUM II trial).

Authors: A. Nelson, A. Shafazand, C. Cahlin, A. Carneiro, H. Helgadottir, M. Levin, M. Rizell, G. Ullenhag, S. Wirén, P. Lindnér, J. Nilsson, L. Ny, R. Olofsson Bagge

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.9533

Paper - **DOI:** 10.1016/j.jval.2019.09.554 - **Authors:** A. Bamrara, N. Mishra, S. Takyar - **Year:** 2019 - **Journal:** Value in Health

A. Bamrara, N. Mishra, S. Takyar · 2019 · Value in Health · DOI

Full title: - **DOI:** 10.1016/j.jval.2019.09.554 - **Authors:** A. Bamrara, N. Mishra, S. Takyar - **Year:** 2019 - **Journal:** Value in Health

Authors: A. Bamrara, N. Mishra, S. Takyar

Year: 2019

Venue: Value in Health

DOI: https://doi.org/10.1016/j.jval.2019.09.554

Paper Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

Allen, Elizabeth, Jabouille, Arnaud, Rivera, Lee B., Lodewijckx, Inge, Missiaen, Rindert, Steri, Veronica, Feyen, Kevin, Tawney, Jaime, Hanahan, Douglas, Michael, Iacovos P., Bergers, Gabriele · 2017 · Science Translational Medicine · DOI

Full title: Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

Authors: Allen, Elizabeth, Jabouille, Arnaud, Rivera, Lee B., Lodewijckx, Inge, Missiaen, Rindert, Steri, Veronica, Feyen, Kevin, Tawney, Jaime, Hanahan, Douglas, Michael, Iacovos P., Bergers, Gabriele

Year: 2017

Venue: Science Translational Medicine

DOI: https://doi.org/10.1126/scitranslmed.aak9679

Paper Combination of immune checkpoint blockade in metastatic colorectal cancers with microsatellite instability: A new standard of care?

Randrian, Violaine, Rousseau, Benoit · 2025 · Med (New York, N.Y.) · DOI

Full title: Combination of immune checkpoint blockade in metastatic colorectal cancers with microsatellite instability: A new standard of care?

Authors: Randrian, Violaine, Rousseau, Benoit

Year: 2025

Venue: Med (New York, N.Y.)

DOI: https://doi.org/10.1016/j.medj.2025.100636

Paper Efficacy and safety of nab-paclitaxel or combined nab-paclitaxel and immune checkpoint inhibitors in relapsed small-cell lung cancer.

Wan, Rui, Guo, Yanrong, Hao, Xuezhi, Wang, Zhijie, Duan, Jianchun, Wang, Jie · 2023 · Therapeutic advances in medical oncology · DOI

Full title: Efficacy and safety of nab-paclitaxel or combined nab-paclitaxel and immune checkpoint inhibitors in relapsed small-cell lung cancer.

Authors: Wan, Rui, Guo, Yanrong, Hao, Xuezhi, Wang, Zhijie, Duan, Jianchun, Wang, Jie

Year: 2023

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359231179315

Paper Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Dewan, Md. Zahidunnabi, Galloway, Ashley E., Kawashima, Noriko, DeWyngaert, J. Keith, Babb, James S., Formenti, Silvia C., Demaria, Sandra · 2009 · Clinical Cancer Research · DOI

Full title: Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Authors: Dewan, Md. Zahidunnabi, Galloway, Ashley E., Kawashima, Noriko, DeWyngaert, J. Keith, Babb, James S., Formenti, Silvia C., Demaria, Sandra

Year: 2009

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-09-0265

Paper Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer

Takei, Shogo, Tanaka, Yosuke, Lin, Yi-Tzu, Koyama, Shohei, Fukuoka, Shota, Hara, Hiroki, Nakamura, Yoshiaki, Kuboki, Yasutoshi, Kotani, Daisuke, Kojima, Takashi, Bando, Hideaki, Mishima, Saori, Ueno, Toshihide, Kojima, Shinya, Wakabayashi, Masashi, Sakamoto, Naoya, Kojima, Motohiro, Kuwata, Takeshi, Yoshino, Takayuki, Nishikawa, Hiroyoshi, Mano, Hiroyuki, Endo, Itaru, Shitara, Kohei, Kawazoe, Akihito · 2024 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer

Authors: Takei, Shogo, Tanaka, Yosuke, Lin, Yi-Tzu, Koyama, Shohei, Fukuoka, Shota, Hara, Hiroki, Nakamura, Yoshiaki, Kuboki, Yasutoshi, Kotani, Daisuke, Kojima, Takashi, Bando, Hideaki, Mishima, Saori, Ueno, Toshihide, Kojima, Shinya, Wakabayashi, Masashi, Sakamoto, Naoya, Kojima, Motohiro, Kuwata, Takeshi, Yoshino, Takayuki, Nishikawa, Hiroyoshi, Mano, Hiroyuki, Endo, Itaru, Shitara, Kohei, Kawazoe, Akihito

Year: 2024

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2023-008210

Paper Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.

Sibaud, Vincent · 2018 · American journal of clinical dermatology · DOI

Full title: Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.

Authors: Sibaud, Vincent

Year: 2018

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-017-0336-3

Paper Associations of Clinical and Molecular Characteristics with the Response to Immune Checkpoint Blockade in Advanced Gastric Cancers.

Xu, Xiaoqing, Li, Jingjing, Gao, Yiding, Lv, Wangxia, Wei, Qing, Tang, Xiaowan, Hu, Jinlin, Yuan, Xing, Wu, Wei, Zhang, Lingnan, Luo, Cong, Chen, Lei, Ying, Jieer, Zhu, Xiu, Xu, Qi · 2022 · Journal of oncology · DOI

Full title: Associations of Clinical and Molecular Characteristics with the Response to Immune Checkpoint Blockade in Advanced Gastric Cancers.

Authors: Xu, Xiaoqing, Li, Jingjing, Gao, Yiding, Lv, Wangxia, Wei, Qing, Tang, Xiaowan, Hu, Jinlin, Yuan, Xing, Wu, Wei, Zhang, Lingnan, Luo, Cong, Chen, Lei, Ying, Jieer, Zhu, Xiu, Xu, Qi

Year: 2022

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2022/2162229

Paper Breaking immune evasion in breast cancer by targeting COX-2/PGE2 pathway.

Zheng, Xuewei, Wang, Junxiang, OuYang, Yanan, Yao, Kaiyuan, Zheng, Jiayu, Zeng, Li, Wang, Jingjing, Chen, Hetao, Du, Haoming, Fu, Dongliao, Shi, Linlin, Zhao, Anshun, Yin, Qinan · 2025 · Molecular and cellular endocrinology · DOI

Full title: Breaking immune evasion in breast cancer by targeting COX-2/PGE2 pathway.

Authors: Zheng, Xuewei, Wang, Junxiang, OuYang, Yanan, Yao, Kaiyuan, Zheng, Jiayu, Zeng, Li, Wang, Jingjing, Chen, Hetao, Du, Haoming, Fu, Dongliao, Shi, Linlin, Zhao, Anshun, Yin, Qinan

Year: 2025

Venue: Molecular and cellular endocrinology

DOI: https://doi.org/10.1016/j.mce.2025.112617

Paper Immune Checkpoint Inhibitor-induced Bilateral Vestibulopathy.

Koch, Elias A T, Nickel, Florian T, Heinzerling, Lucie, Schulz, Yvonne K, Berking, Carola, Erdmann, Michael · 2021 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Immune Checkpoint Inhibitor-induced Bilateral Vestibulopathy.

Authors: Koch, Elias A T, Nickel, Florian T, Heinzerling, Lucie, Schulz, Yvonne K, Berking, Carola, Erdmann, Michael

Year: 2021

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000353

Paper SMARCB1/INI-1-Deficient sinonasal carcinoma demonstrates a poor prognosis but favorable clinical outcomes after PD-1/PD-L1 inhibitor therapy: A case series

Shuhan Zhao, Hao Du, Zhanjie Zhang, Jinsong Yang, You Zhou, Guixiang Xiao, Hui Ma, Caini Lan, Jinzi Liang, Kunyu Yang, Lu Wen · 2025 · Science in progress · DOI

Full title: SMARCB1/INI-1-Deficient sinonasal carcinoma demonstrates a poor prognosis but favorable clinical outcomes after PD-1/PD-L1 inhibitor therapy: A case series

Authors: Shuhan Zhao, Hao Du, Zhanjie Zhang, Jinsong Yang, You Zhou, Guixiang Xiao, Hui Ma, Caini Lan, Jinzi Liang, Kunyu Yang, Lu Wen

Year: 2025

Venue: Science in progress

DOI: https://doi.org/10.1177/00368504251315075

Paper Atypical severe immune-related adverse effects resulting from sequenced immunotherapy in melanoma.

Danlos, François-Xavier, Pagès, Cécile, Roux, Jennifer, Jebali, Majdi, Gornet, Jean-Marc, Bagot, Martine, Lebbé, Céleste · 2015 · Melanoma research · DOI

Full title: Atypical severe immune-related adverse effects resulting from sequenced immunotherapy in melanoma.

Authors: Danlos, François-Xavier, Pagès, Cécile, Roux, Jennifer, Jebali, Majdi, Gornet, Jean-Marc, Bagot, Martine, Lebbé, Céleste

Year: 2015

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000132

Paper Combination Immunotherapy of Advanced Lymphoma with Oncolytic Vaccinia Virus and Checkpoint Inhibitor Following Local Tumor Irradiation

B. Minev, H. Kohrt, M. Kilinc, N. Chen, A. Feng, M. Pessian, Ulrike Geissinger, Erik S. Haefner, D. Tsoneva, K. Bozhilov, Idit Sagiv Barfi, Xing Zhao, Narendiran Rajasekaran, R. Levy, A. Szalay · 2014 · Blood · DOI

Full title: Combination Immunotherapy of Advanced Lymphoma with Oncolytic Vaccinia Virus and Checkpoint Inhibitor Following Local Tumor Irradiation

Authors: B. Minev, H. Kohrt, M. Kilinc, N. Chen, A. Feng, M. Pessian, Ulrike Geissinger, Erik S. Haefner, D. Tsoneva, K. Bozhilov, Idit Sagiv Barfi, Xing Zhao, Narendiran Rajasekaran, R. Levy, A. Szalay

Year: 2014

Venue: Blood

DOI: https://doi.org/10.1182/blood.v124.21.4487.4487

Paper Efficacy of PD-1/PD-L1 inhibitors in advanced hepatocellular carcinoma: A systematic review and meta-analysis.

Peng, Tzu-Rong, Yang, Li-Jou, Wu, Ta-Wei · 2024 · Tzu chi medical journal · DOI

Full title: Efficacy of PD-1/PD-L1 inhibitors in advanced hepatocellular carcinoma: A systematic review and meta-analysis.

Authors: Peng, Tzu-Rong, Yang, Li-Jou, Wu, Ta-Wei

Year: 2024

Venue: Tzu chi medical journal

DOI: https://doi.org/10.4103/tcmj.tcmj_159_23

Paper A review on immune checkpoint blockage therapy

Shajahan, Thamrook s, Dharan, Shaiju S, Nj, Merlin · 2020 · International Journal of Research in Hospital and Clinical Pharmacy · DOI

Full title: A review on immune checkpoint blockage therapy

Authors: Shajahan, Thamrook s, Dharan, Shaiju S, Nj, Merlin

Year: 2020

Venue: International Journal of Research in Hospital and Clinical Pharmacy

DOI: https://doi.org/10.33974/ijrhcp.v2i1.159

Paper Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

Masterson, Liam, Howard, James, Gonzalez-Cruz, Jazmina, Jackson, Christopher, Barnett, Catherine, Overton, Lewis, Liu, Howard, Ladwa, Rahul, Simpson, Fiona, McGrath, Margie, Wallwork, Ben, Jones, Terry, Ottensmeier, Christian, Chua, Melvin L K, Perry, Chris, Khanna, Rajiv, Panizza, Benedict, Porceddu, Sandro, Lechner, Matt · 2020 · International journal of cancer · DOI

Full title: Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

Authors: Masterson, Liam, Howard, James, Gonzalez-Cruz, Jazmina, Jackson, Christopher, Barnett, Catherine, Overton, Lewis, Liu, Howard, Ladwa, Rahul, Simpson, Fiona, McGrath, Margie, Wallwork, Ben, Jones, Terry, Ottensmeier, Christian, Chua, Melvin L K, Perry, Chris, Khanna, Rajiv, Panizza, Benedict, Porceddu, Sandro, Lechner, Matt

Year: 2020

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.32869

Paper The landscape of contemporary clinical trials for untreated metastatic clear cell renal cell carcinoma

Zhang, Tian, Hwang, Joyce K., George, Daniel J., Pal, Sumanta K. · 2020 · Cancer Treatment and Research Communications · DOI

Full title: The landscape of contemporary clinical trials for untreated metastatic clear cell renal cell carcinoma

Authors: Zhang, Tian, Hwang, Joyce K., George, Daniel J., Pal, Sumanta K.

Year: 2020

Venue: Cancer Treatment and Research Communications

DOI: https://doi.org/10.1016/j.ctarc.2020.100183

Paper Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer.

Seo, Yongwoo David, Jiang, Xiuyun, Sullivan, Kevin M, Jalikis, Florencia G, Smythe, Kimberly S, Abbasi, Arezou, Vignali, Marissa, Park, James O, Daniel, Sara K, Pollack, Seth M, Kim, Teresa S, Yeung, Raymond, Crispe, Ian Nicholas, Pierce, Robert H, Robins, Harlan, Pillarisetty, Venu G · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer.

Authors: Seo, Yongwoo David, Jiang, Xiuyun, Sullivan, Kevin M, Jalikis, Florencia G, Smythe, Kimberly S, Abbasi, Arezou, Vignali, Marissa, Park, James O, Daniel, Sara K, Pollack, Seth M, Kim, Teresa S, Yeung, Raymond, Crispe, Ian Nicholas, Pierce, Robert H, Robins, Harlan, Pillarisetty, Venu G

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-19-0081

Paper Immunotargeted therapy in melanoma: patient, provider preferences, and willingness to pay at an academic cancer center.

Stenehjem, David D, Au, Trang H, Ngorsuraches, Surachat, Ma, Junjie, Bauer, Hillevi, Wanishayakorn, Tanatape, Nelson, Ryan S, Pfeiffer, Constance M, Schwartz, Joshua, Korytowsky, Beata, Oderda, Gary, Brixner, Diana I · 2019 · Melanoma research · DOI

Full title: Immunotargeted therapy in melanoma: patient, provider preferences, and willingness to pay at an academic cancer center.

Authors: Stenehjem, David D, Au, Trang H, Ngorsuraches, Surachat, Ma, Junjie, Bauer, Hillevi, Wanishayakorn, Tanatape, Nelson, Ryan S, Pfeiffer, Constance M, Schwartz, Joshua, Korytowsky, Beata, Oderda, Gary, Brixner, Diana I

Year: 2019

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000572

Paper Cardiovascular toxicity with CTLA-4 inhibitors in cancer patients: A meta-analysis.

Liu, Huiyi, Fu, Lu, Jin, Shuyu, Ye, Xingdong, Chen, Yanlin, Pu, Sijia, Xue, Yumei · 2024 · Cancer innovation · DOI

Full title: Cardiovascular toxicity with CTLA-4 inhibitors in cancer patients: A meta-analysis.

Authors: Liu, Huiyi, Fu, Lu, Jin, Shuyu, Ye, Xingdong, Chen, Yanlin, Pu, Sijia, Xue, Yumei

Year: 2024

Venue: Cancer innovation

DOI: https://doi.org/10.1002/cai2.116

Paper Abstract IA005: Generating T cell responses against pancreatic cancer

Byrne, Katelyn T. · 2022 · Cancer Research · DOI

Full title: Abstract IA005: Generating T cell responses against pancreatic cancer

Authors: Byrne, Katelyn T.

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.panca22-ia005

Paper FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy.

Chen, Xin, Song, Xiaomin, Li, Kang, Zhang, Tong · 2019 · Frontiers in immunology · DOI

Full title: FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy.

Authors: Chen, Xin, Song, Xiaomin, Li, Kang, Zhang, Tong

Year: 2019

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2019.00292

Paper Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade.

Davidson, Tara, Zhang, Henan, Dong, Haidong, Grams, Michael P, Park, Sean S, Yan, Yiyi · 2022 · Advances in radiation oncology · DOI

Full title: Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade.

Authors: Davidson, Tara, Zhang, Henan, Dong, Haidong, Grams, Michael P, Park, Sean S, Yan, Yiyi

Year: 2022

Venue: Advances in radiation oncology

DOI: https://doi.org/10.1016/j.adro.2022.100931

Paper Precision and predictive medicine in urothelial cancer: are we making progress?

Bellmunt, Joaquim, Orsola, Anna, Sonpavde, Guru · 2015 · European urology · DOI

Full title: Precision and predictive medicine in urothelial cancer: are we making progress?

Authors: Bellmunt, Joaquim, Orsola, Anna, Sonpavde, Guru

Year: 2015

Venue: European urology

DOI: https://doi.org/10.1016/j.eururo.2015.04.025

Paper Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma.

Ménard, Marie, Yoda, Hiroyuki, Nasholm, Nicole, Barata, Megumi J, Wang, Linyu, Simonds, Erin F, Lu, Edbert D, Wong-Michalak, Shannon, McHenry, Lauren, Farrel, Alvin, Kaufman, Rebecca, Lopez, Vanessa, Kennedy, Rebekah J, Fernandez, G Esteban, Shimada, Hiroyuki, Grossmann, Liron D, Asgharzadeh, Shahab, Maris, John M, Gustafson, W Clay, Weiss, William A · 2025 · The Journal of experimental medicine · DOI

Full title: Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma.

Authors: Ménard, Marie, Yoda, Hiroyuki, Nasholm, Nicole, Barata, Megumi J, Wang, Linyu, Simonds, Erin F, Lu, Edbert D, Wong-Michalak, Shannon, McHenry, Lauren, Farrel, Alvin, Kaufman, Rebecca, Lopez, Vanessa, Kennedy, Rebekah J, Fernandez, G Esteban, Shimada, Hiroyuki, Grossmann, Liron D, Asgharzadeh, Shahab, Maris, John M, Gustafson, W Clay, Weiss, William A

Year: 2025

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20231417

Paper The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System.

Moon, Edmund K, Langer, Corey J, Albelda, Steven M · 2017 · Annals of the American Thoracic Society · DOI

Full title: The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System.

Authors: Moon, Edmund K, Langer, Corey J, Albelda, Steven M

Year: 2017

Venue: Annals of the American Thoracic Society

DOI: https://doi.org/10.1513/AnnalsATS.201702-152FR

Paper A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea in patients with advanced melanoma treated with the checkpoint inhibitor tremelimumab.

Friedlander, Philip, Wood, Kevin, Wassmann, Karl, Christenfeld, Alan M, Bhardwaj, Nina, Oh, William K · 2018 · Journal for immunotherapy of cancer · DOI

Full title: A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea in patients with advanced melanoma treated with the checkpoint inhibitor tremelimumab.

Authors: Friedlander, Philip, Wood, Kevin, Wassmann, Karl, Christenfeld, Alan M, Bhardwaj, Nina, Oh, William K

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0408-9

Paper Efficacy and toxicity profile of first-line treatment for extensive-stage small cell lung cancer: A Bayesian network meta-analysis.

Lin, Guo, Yao, Zhuoran, Kang, Kai, Wang, Hui, Luo, Ren, Lu, You · 2023 · Cancer medicine · DOI

Full title: Efficacy and toxicity profile of first-line treatment for extensive-stage small cell lung cancer: A Bayesian network meta-analysis.

Authors: Lin, Guo, Yao, Zhuoran, Kang, Kai, Wang, Hui, Luo, Ren, Lu, You

Year: 2023

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.5750

Paper Reinstating immunogenicity using bispecific anti-checkpoint/agent inhibitors.

Mortezaee, Keywan, Majidpoor, Jamal · 2023 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Reinstating immunogenicity using bispecific anti-checkpoint/agent inhibitors.

Authors: Mortezaee, Keywan, Majidpoor, Jamal

Year: 2023

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2023.114621

Paper MOVIE: a phase I, open-label, multicenter study to evaluate the safety and tolerability of metronomic vinorelbine combined with durvalumab plus tremelimumab in patients with advanced solid tumors.

Vicier, C, Isambert, N, Cropet, C, Hamimed, M, Osanno, L, Legrand, F, de La Motte Rouge, T, Ciccolini, J, Gonçalves, A · 2022 · ESMO open · DOI

Full title: MOVIE: a phase I, open-label, multicenter study to evaluate the safety and tolerability of metronomic vinorelbine combined with durvalumab plus tremelimumab in patients with advanced solid tumors.

Authors: Vicier, C, Isambert, N, Cropet, C, Hamimed, M, Osanno, L, Legrand, F, de La Motte Rouge, T, Ciccolini, J, Gonçalves, A

Year: 2022

Venue: ESMO open

DOI: https://doi.org/10.1016/j.esmoop.2022.100646

Paper [Management of adverse events in immune oncology - Practical aspects of immune-related adverse events during immune oncological treatment].

Reinmuth, Niels, Bitzer, Michael, Deschler-Baier, Barbara, Fischer, Jürgen R, Kuon, Jonas, Leipe, Jan, Rawluk, Justyna, Schulz, Christian, Heußel, Claus Peter, Schultheiß, Michael · 2019 · Deutsche medizinische Wochenschrift (1946) · DOI

Full title: [Management of adverse events in immune oncology - Practical aspects of immune-related adverse events during immune oncological treatment].

Authors: Reinmuth, Niels, Bitzer, Michael, Deschler-Baier, Barbara, Fischer, Jürgen R, Kuon, Jonas, Leipe, Jan, Rawluk, Justyna, Schulz, Christian, Heußel, Claus Peter, Schultheiß, Michael

Year: 2019

Venue: Deutsche medizinische Wochenschrift (1946)

DOI: https://doi.org/10.1055/a-0739-8194

Paper Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns.

Nikanjam, Mina, Patel, Harsh, Kurzrock, Razelle · 2017 · Oncoimmunology · DOI

Full title: Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns.

Authors: Nikanjam, Mina, Patel, Harsh, Kurzrock, Razelle

Year: 2017

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2017.1338997

Paper Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.

Schwartz, Anthony L, Nath, Pulak R, Allgauer, Michael, Lessey-Morillon, Elizabeth C, Sipes, John M, Ridnour, Lisa A, Morillon Ii, Y Maurice, Yu, Zhiya, Restifo, Nicholas P, Roberts, David D · 2019 · Cancer immunology, immunotherapy : CII · DOI

Full title: Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.

Authors: Schwartz, Anthony L, Nath, Pulak R, Allgauer, Michael, Lessey-Morillon, Elizabeth C, Sipes, John M, Ridnour, Lisa A, Morillon Ii, Y Maurice, Yu, Zhiya, Restifo, Nicholas P, Roberts, David D

Year: 2019

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-019-02397-7

Paper Long term survival with cytotoxic T lymphocyte-associated antigen 4 blockade using tremelimumab.

Eroglu, Zeynep, Kim, Dae Won, Wang, Xiaoyan, Camacho, Luis H, Chmielowski, Bartosz, Seja, Elizabeth, Villanueva, Arturo, Ruchalski, Kathleen, Glaspy, John A, Kim, Kevin B, Hwu, Wen-Jen, Ribas, Antoni · 2015 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Long term survival with cytotoxic T lymphocyte-associated antigen 4 blockade using tremelimumab.

Authors: Eroglu, Zeynep, Kim, Dae Won, Wang, Xiaoyan, Camacho, Luis H, Chmielowski, Bartosz, Seja, Elizabeth, Villanueva, Arturo, Ruchalski, Kathleen, Glaspy, John A, Kim, Kevin B, Hwu, Wen-Jen, Ribas, Antoni

Year: 2015

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2015.08.012

Paper Combination Controversies: Checkpoint Inhibition Alone or in Combination for the Treatment of Melanoma?

Warner, Allison Betof, Postow, Michael A · 2018 · Oncology (Williston Park, N.Y.)

Full title: Combination Controversies: Checkpoint Inhibition Alone or in Combination for the Treatment of Melanoma?

Authors: Warner, Allison Betof, Postow, Michael A

Year: 2018

Venue: Oncology (Williston Park, N.Y.)

Paper 4-1BB+ Tregs and inhibitory progenitor exhausted T cells confer resistance to anti-PD-L1 and anti-CTLA-4 combination therapy.

Cha, Junha, Kim, Chang Gon, Sim, Nam Suk, Kim, Gamin, Son, Wonrak, Kim, Dahee, Jung, Yurim, Hong, Hyun Jun, Lee, Hae Been, Kim, Jaehyung, Kim, Jinna, Yoon, Sun Och, Go, Seokhyeong, Kim, Jeongah, Seong, Euijung, Baek, Seungbyn, Kim, Kyung Hwan, Hong, Min Hee, Koh, Yoon Woo, Lee, Insuk, Kim, Hye Ryun · 2025 · Cell reports. Medicine · DOI

Full title: 4-1BB+ Tregs and inhibitory progenitor exhausted T cells confer resistance to anti-PD-L1 and anti-CTLA-4 combination therapy.

Authors: Cha, Junha, Kim, Chang Gon, Sim, Nam Suk, Kim, Gamin, Son, Wonrak, Kim, Dahee, Jung, Yurim, Hong, Hyun Jun, Lee, Hae Been, Kim, Jaehyung, Kim, Jinna, Yoon, Sun Och, Go, Seokhyeong, Kim, Jeongah, Seong, Euijung, Baek, Seungbyn, Kim, Kyung Hwan, Hong, Min Hee, Koh, Yoon Woo, Lee, Insuk, Kim, Hye Ryun

Year: 2025

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2025.102408

Paper Tumour neoantigen heterogeneity thresholds provide a time window for combination immunotherapy.

Aguadé-Gorgorió, Guim, Solé, Ricard · 2020 · Journal of the Royal Society, Interface · DOI

Full title: Tumour neoantigen heterogeneity thresholds provide a time window for combination immunotherapy.

Authors: Aguadé-Gorgorió, Guim, Solé, Ricard

Year: 2020

Venue: Journal of the Royal Society, Interface

DOI: https://doi.org/10.1098/rsif.2020.0736

Paper NXPH4 Used as a New Prognostic and Immunotherapeutic Marker for Muscle-Invasive Bladder Cancer.

Gui, Zhiming, Ying, Xiaoling, Liu, Chunxiao · 2022 · Journal of oncology · DOI

Full title: NXPH4 Used as a New Prognostic and Immunotherapeutic Marker for Muscle-Invasive Bladder Cancer.

Authors: Gui, Zhiming, Ying, Xiaoling, Liu, Chunxiao

Year: 2022

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2022/4271409

Paper Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

Motzer, Robert J., Tannir, Nizar M., McDermott, Ray, Frontera, Osvaldo Arén, Melichar, Bohuslav, Choueiri, Toni K., Plimack, Elizabeth R., Barthélémy, Philippe, Porta, Camillo, George, Saby, Powles, Thomas, Donskov, Frede, Neiman, Victoria, Kollmannsberger, Christian, Salman, Pamela, Gurney, Howard, Hawkins, Robert D., Ravaud, Alain, Grimm, Marc‐Oliver, Bracarda, Sergio, Barrios, Carlos H., Tomita, Yoshihiko, Castellano, Daniel, Rini, Brian I., Chen, Allen C., Mekan, Sabeen, McHenry, M. Brent, Wind‐Rotolo, Megan, Doan, Justin, Sharma, Padmanee, Hammers, Hans J., Escudier, Bernard · 2018 · New England Journal of Medicine · DOI

Full title: Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

Authors: Motzer, Robert J., Tannir, Nizar M., McDermott, Ray, Frontera, Osvaldo Arén, Melichar, Bohuslav, Choueiri, Toni K., Plimack, Elizabeth R., Barthélémy, Philippe, Porta, Camillo, George, Saby, Powles, Thomas, Donskov, Frede, Neiman, Victoria, Kollmannsberger, Christian, Salman, Pamela, Gurney, Howard, Hawkins, Robert D., Ravaud, Alain, Grimm, Marc‐Oliver, Bracarda, Sergio, Barrios, Carlos H., Tomita, Yoshihiko, Castellano, Daniel, Rini, Brian I., Chen, Allen C., Mekan, Sabeen, McHenry, M. Brent, Wind‐Rotolo, Megan, Doan, Justin, Sharma, Padmanee, Hammers, Hans J., Escudier, Bernard

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1712126

Paper Melanoma therapy: Check the checkpoints.

Furue, Masutaka, Kadono, Takafumi · 2016 · The Journal of dermatology · DOI

Full title: Melanoma therapy: Check the checkpoints.

Authors: Furue, Masutaka, Kadono, Takafumi

Year: 2016

Venue: The Journal of dermatology

DOI: https://doi.org/10.1111/1346-8138.13257

Paper Activity and safety of CTLA-4 blockade combined with vaccines in cynomolgus macaques.

Keler, Tibor, Halk, Ed, Vitale, Laura, O'Neill, Tom, Blanset, Diann, Lee, Steven, Srinivasan, Mohan, Graziano, Robert F, Davis, Thomas, Lonberg, Nils, Korman, Alan · 2003 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Activity and safety of CTLA-4 blockade combined with vaccines in cynomolgus macaques.

Authors: Keler, Tibor, Halk, Ed, Vitale, Laura, O'Neill, Tom, Blanset, Diann, Lee, Steven, Srinivasan, Mohan, Graziano, Robert F, Davis, Thomas, Lonberg, Nils, Korman, Alan

Year: 2003

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.171.11.6251

Paper Efficacy and safety of PD-1/PD-L1 inhibitors combined with CTLA-4 inhibitor versus chemotherapy for advanced lung cancer: A meta-analysis.

Zhang, Pei-Pei, Wang, Juan, Ding, Da-Zhi, Zhang, Li, Cheng, Chun, Chen, Da-Ke · 2021 · Medicine · DOI

Full title: Efficacy and safety of PD-1/PD-L1 inhibitors combined with CTLA-4 inhibitor versus chemotherapy for advanced lung cancer: A meta-analysis.

Authors: Zhang, Pei-Pei, Wang, Juan, Ding, Da-Zhi, Zhang, Li, Cheng, Chun, Chen, Da-Ke

Year: 2021

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000027121

Paper Circulating Tumor Cell Subtypes and T-cell Populations as Prognostic Biomarkers to Combination Immunotherapy in Patients with Metastatic Genitourinary Cancer.

Chalfin, Heather J, Pramparo, Tiziano, Mortazavi, Amir, Niglio, Scot A, Schonhoft, Joseph D, Jendrisak, Adam, Chu, Yen-Lin, Richardson, Robin, Krupa, Rachel, Anderson, Amanda K L, Wang, Yipeng, Dittamore, Ryan, Pal, Sumanta K, Lara, Primo N, Stein, Mark N, Quinn, David I, Steinberg, Seth M, Cordes, Lisa M, Ley, Lisa, Mallek, Marissa, Sierra Ortiz, Olena, Costello, Rene, Cadena, Jacqueline, Diaz, Carlos, Gulley, James L, Dahut, William L, Streicher, Howard, Wright, John J, Trepel, Jane B, Bottaro, Donald P, Apolo, Andrea B · 2021 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Circulating Tumor Cell Subtypes and T-cell Populations as Prognostic Biomarkers to Combination Immunotherapy in Patients with Metastatic Genitourinary Cancer.

Authors: Chalfin, Heather J, Pramparo, Tiziano, Mortazavi, Amir, Niglio, Scot A, Schonhoft, Joseph D, Jendrisak, Adam, Chu, Yen-Lin, Richardson, Robin, Krupa, Rachel, Anderson, Amanda K L, Wang, Yipeng, Dittamore, Ryan, Pal, Sumanta K, Lara, Primo N, Stein, Mark N, Quinn, David I, Steinberg, Seth M, Cordes, Lisa M, Ley, Lisa, Mallek, Marissa, Sierra Ortiz, Olena, Costello, Rene, Cadena, Jacqueline, Diaz, Carlos, Gulley, James L, Dahut, William L, Streicher, Howard, Wright, John J, Trepel, Jane B, Bottaro, Donald P, Apolo, Andrea B

Year: 2021

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2891

Paper Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

Hooijkaas, Anna, Gadiot, Jules, Morrow, Michelle, Stewart, Ross, Schumacher, Ton, Blank, Christian U · 2012 · Oncoimmunology · DOI

Full title: Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

Authors: Hooijkaas, Anna, Gadiot, Jules, Morrow, Michelle, Stewart, Ross, Schumacher, Ton, Blank, Christian U

Year: 2012

Venue: Oncoimmunology

DOI: https://doi.org/10.4161/onci.20226

Paper PD-1/PD-L1 counterattack alliance: multiple strategies for treating triple-negative breast cancer

Zhu, Haiying, Du, Chengyong, Yuan, Meng, Fu, Peifen, He, Qiaojun, Yang, Bo, Cao, Ji · 2020 · Drug Discovery Today · DOI

Full title: PD-1/PD-L1 counterattack alliance: multiple strategies for treating triple-negative breast cancer

Authors: Zhu, Haiying, Du, Chengyong, Yuan, Meng, Fu, Peifen, He, Qiaojun, Yang, Bo, Cao, Ji

Year: 2020

Venue: Drug Discovery Today

DOI: https://doi.org/10.1016/j.drudis.2020.07.006

Paper A guide to cancer immunotherapy: from T cell basic science to clinical practice

Waldman, Alex D., Fritz, Jill M., Lenardo, Michael J. · 2020 · Nature reviews. Immunology · DOI

Full title: A guide to cancer immunotherapy: from T cell basic science to clinical practice

Authors: Waldman, Alex D., Fritz, Jill M., Lenardo, Michael J.

Year: 2020

Venue: Nature reviews. Immunology

DOI: https://doi.org/10.1038/s41577-020-0306-5

Paper Radiotherapy induces responses of lung cancer to CTLA-4 blockade.

Formenti, Silvia C, Rudqvist, Nils-Petter, Golden, Encouse, Cooper, Benjamin, Wennerberg, Erik, Lhuillier, Claire, Vanpouille-Box, Claire, Friedman, Kent, Ferrari de Andrade, Lucas, Wucherpfennig, Kai W, Heguy, Adriana, Imai, Naoko, Gnjatic, Sacha, Emerson, Ryan O, Zhou, Xi Kathy, Zhang, Tuo, Chachoua, Abraham, Demaria, Sandra · 2018 · Nature medicine · DOI

Full title: Radiotherapy induces responses of lung cancer to CTLA-4 blockade.

Authors: Formenti, Silvia C, Rudqvist, Nils-Petter, Golden, Encouse, Cooper, Benjamin, Wennerberg, Erik, Lhuillier, Claire, Vanpouille-Box, Claire, Friedman, Kent, Ferrari de Andrade, Lucas, Wucherpfennig, Kai W, Heguy, Adriana, Imai, Naoko, Gnjatic, Sacha, Emerson, Ryan O, Zhou, Xi Kathy, Zhang, Tuo, Chachoua, Abraham, Demaria, Sandra

Year: 2018

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-018-0232-2

Paper Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Auslander, Noam, Zhang, Gao, Lee, Joo Sang, Frederick, Dennie T, Miao, Benchun, Moll, Tabea, Tian, Tian, Wei, Zhi, Madan, Sanna, Sullivan, Ryan J, Boland, Genevieve, Flaherty, Keith, Herlyn, Meenhard, Ruppin, Eytan · 2018 · Nature medicine · DOI

Full title: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Authors: Auslander, Noam, Zhang, Gao, Lee, Joo Sang, Frederick, Dennie T, Miao, Benchun, Moll, Tabea, Tian, Tian, Wei, Zhi, Madan, Sanna, Sullivan, Ryan J, Boland, Genevieve, Flaherty, Keith, Herlyn, Meenhard, Ruppin, Eytan

Year: 2018

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-018-0157-9

Paper PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.

Zhao, Yunlong, Lee, Calvin K, Lin, Chia-Hao, Gassen, Rodrigo B, Xu, Xiaozheng, Huang, Zhe, Xiao, Changchun, Bonorino, Cristina, Lu, Li-Fan, Bui, Jack D, Hui, Enfu · 2019 · Immunity · DOI

Full title: PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.

Authors: Zhao, Yunlong, Lee, Calvin K, Lin, Chia-Hao, Gassen, Rodrigo B, Xu, Xiaozheng, Huang, Zhe, Xiao, Changchun, Bonorino, Cristina, Lu, Li-Fan, Bui, Jack D, Hui, Enfu

Year: 2019

Venue: Immunity

DOI: https://doi.org/10.1016/j.immuni.2019.11.003

Paper Recent Advances in Systemic Therapy for Hepatocellular Carcinoma in an Aging Society: 2020 Update.

Kudo, Masatoshi · 2020 · Liver cancer · DOI

Full title: Recent Advances in Systemic Therapy for Hepatocellular Carcinoma in an Aging Society: 2020 Update.

Authors: Kudo, Masatoshi

Year: 2020

Venue: Liver cancer

DOI: https://doi.org/10.1159/000511001

Paper The efficacy and safety of combination therapy with immune checkpoint inhibitors in non-small cell lung cancer: A meta-analysis.

Mo, Dun-Chang, Huang, Jian-Feng, Luo, Peng-Hui, Huang, Shang-Xiao, Wang, Han-Lei · 2021 · International immunopharmacology · DOI

Full title: The efficacy and safety of combination therapy with immune checkpoint inhibitors in non-small cell lung cancer: A meta-analysis.

Authors: Mo, Dun-Chang, Huang, Jian-Feng, Luo, Peng-Hui, Huang, Shang-Xiao, Wang, Han-Lei

Year: 2021

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2021.107594

Paper T-cell and NK-cell infiltration into solid tumors: a key limiting factor for efficacious cancer immunotherapy.

Melero, Ignacio, Rouzaut, Ana, Motz, Greg T, Coukos, George · 2014 · Cancer discovery · DOI

Full title: T-cell and NK-cell infiltration into solid tumors: a key limiting factor for efficacious cancer immunotherapy.

Authors: Melero, Ignacio, Rouzaut, Ana, Motz, Greg T, Coukos, George

Year: 2014

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-13-0985

Paper Combining Radiotherapy with Immunocheckpoint Inhibitors or CAR-T in Renal Cell Carcinoma.

Santoni, Matteo, Heng, Daniel Y C, Aurilio, Gaetano, Iozzelli, Andrea, Servi, Lucilla, Fabiani, Andrea, Giannini, Massimo, Mazzucchelli, Roberta, Cimadamore, Alessia, Scarpelli, Marina, Zaghloul, Mohamed S, Battelli, Nicola, Montironi, Rodolfo · 2020 · Current drug targets · DOI

Full title: Combining Radiotherapy with Immunocheckpoint Inhibitors or CAR-T in Renal Cell Carcinoma.

Authors: Santoni, Matteo, Heng, Daniel Y C, Aurilio, Gaetano, Iozzelli, Andrea, Servi, Lucilla, Fabiani, Andrea, Giannini, Massimo, Mazzucchelli, Roberta, Cimadamore, Alessia, Scarpelli, Marina, Zaghloul, Mohamed S, Battelli, Nicola, Montironi, Rodolfo

Year: 2020

Venue: Current drug targets

DOI: https://doi.org/10.2174/1389450120666191017113051

Paper A Folate Receptor β-Targeted TLR7 Agonist Significantly Augments Checkpoint Inhibitor Potencies by Reprogramming Tumor-Associated Macrophages and Myeloid-Derived Suppressor Cells.

Napoleon, John V, Alfar, Rami, Zhang, Fenghua, Raine, Emily A, Wolt, Taylor A, Low, Philip S · 2026 · Journal of medicinal chemistry · DOI

Full title: A Folate Receptor β-Targeted TLR7 Agonist Significantly Augments Checkpoint Inhibitor Potencies by Reprogramming Tumor-Associated Macrophages and Myeloid-Derived Suppressor Cells.

Authors: Napoleon, John V, Alfar, Rami, Zhang, Fenghua, Raine, Emily A, Wolt, Taylor A, Low, Philip S

Year: 2026

Venue: Journal of medicinal chemistry

DOI: https://doi.org/10.1021/acs.jmedchem.5c03277

Paper Efficacy and Safety of Programmed Death 1/Programmed Death-Ligand 1 Plus Cytotoxic T-Lymphocyte-Associated Antigen 4 Inhibitors for Advanced or Metastatic Non-Small Cell Lung Cancer: A Meta-analysis Based on Randomized Controlled Trials.

Ren, Wei, Fang, Yingying, He, Yujing, Ren, Yifeng, Wang, Minfang, Xu, Anyi, Ruan, Jiale, Tao, Qinghua · 2024 · Therapeutic drug monitoring · DOI

Full title: Efficacy and Safety of Programmed Death 1/Programmed Death-Ligand 1 Plus Cytotoxic T-Lymphocyte-Associated Antigen 4 Inhibitors for Advanced or Metastatic Non-Small Cell Lung Cancer: A Meta-analysis Based on Randomized Controlled Trials.

Authors: Ren, Wei, Fang, Yingying, He, Yujing, Ren, Yifeng, Wang, Minfang, Xu, Anyi, Ruan, Jiale, Tao, Qinghua

Year: 2024

Venue: Therapeutic drug monitoring

DOI: https://doi.org/10.1097/FTD.0000000000001228

Paper Inhibitors of Cytotoxic T Lymphocyte Antigen 4 and Programmed Death 1/Programmed Death 1 Ligand for Metastatic Melanoma, Dual Versus Monotherapy-Summary of Advances and Future Directions for Studying These Drugs.

Loo, Kimberly, Daud, Adil I · 2017 · Cancer journal (Sudbury, Mass.) · DOI

Full title: Inhibitors of Cytotoxic T Lymphocyte Antigen 4 and Programmed Death 1/Programmed Death 1 Ligand for Metastatic Melanoma, Dual Versus Monotherapy-Summary of Advances and Future Directions for Studying These Drugs.

Authors: Loo, Kimberly, Daud, Adil I

Year: 2017

Venue: Cancer journal (Sudbury, Mass.)

DOI: https://doi.org/10.1097/PPO.0000000000000238

Paper Intratumoral immunosuppression profiles in 11q-deleted neuroblastomas provide new potential therapeutic targets.

Coronado, Esther, Yañez, Yania, Vidal, Enrique, Rubio, Luis, Vera-Sempere, Francisco, Cañada-Martínez, Antonio José, Panadero, Joaquín, Cañete, Adela, Ladenstein, Ruth, Castel, Victoria, Font de Mora, Jaime · 2021 · Molecular oncology · DOI

Full title: Intratumoral immunosuppression profiles in 11q-deleted neuroblastomas provide new potential therapeutic targets.

Authors: Coronado, Esther, Yañez, Yania, Vidal, Enrique, Rubio, Luis, Vera-Sempere, Francisco, Cañada-Martínez, Antonio José, Panadero, Joaquín, Cañete, Adela, Ladenstein, Ruth, Castel, Victoria, Font de Mora, Jaime

Year: 2021

Venue: Molecular oncology

DOI: https://doi.org/10.1002/1878-0261.12868

Paper Current and future immunotherapy approaches in ovarian cancer

Demircan, Nazım Can, Boussios, Stergios, Taşçı, Tolga, Öztürk, Mehmet Akif · 2020 · Annals of Translational Medicine · DOI

Full title: Current and future immunotherapy approaches in ovarian cancer

Authors: Demircan, Nazım Can, Boussios, Stergios, Taşçı, Tolga, Öztürk, Mehmet Akif

Year: 2020

Venue: Annals of Translational Medicine

DOI: https://doi.org/10.21037/atm-20-4499

Paper The clinical added value of the addition of anti-CTL-4 to anti-PD-1 alone is questionable and clearly increasing toxicity regarding pivotal studies in the treatment of melanoma and renal carcinoma.

Albin, Nicolas, Monard, Adrien, Lapiere, Jérémy · 2019 · Cancer chemotherapy and pharmacology · DOI

Full title: The clinical added value of the addition of anti-CTL-4 to anti-PD-1 alone is questionable and clearly increasing toxicity regarding pivotal studies in the treatment of melanoma and renal carcinoma.

Authors: Albin, Nicolas, Monard, Adrien, Lapiere, Jérémy

Year: 2019

Venue: Cancer chemotherapy and pharmacology

DOI: https://doi.org/10.1007/s00280-019-03804-7

Paper Phase II evaluation of combination immunotherapy with CV301, N-803, bintrafusp alfa, and M9241 in patients with advanced small bowel and colorectal cancers.

Pastor, Danielle M., Redman, Jason M., Floudas, Charalampos S., Lamping, Elizabeth, Francis, Deneise C, Cordes, Lisa M., Marté, Jennifer L., Schlom, Jeffrey, Gulley, James L., Strauss, Julius · 2023 · Journal of Clinical Oncology · DOI

Full title: Phase II evaluation of combination immunotherapy with CV301, N-803, bintrafusp alfa, and M9241 in patients with advanced small bowel and colorectal cancers.

Authors: Pastor, Danielle M., Redman, Jason M., Floudas, Charalampos S., Lamping, Elizabeth, Francis, Deneise C, Cordes, Lisa M., Marté, Jennifer L., Schlom, Jeffrey, Gulley, James L., Strauss, Julius

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.4_suppl.116

Paper Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1.

Mukherjee, Debayan, Romano, Erminia, Walshaw, Richard, Zeef, Leo A H, Banyard, Antonia, Kitcatt, Stephen J, Cheadle, Eleanor J, Tuomela, Karoliina, Pendharkar, Swati, Al-Deka, Aws, Salerno, Beatrice, Raby, Sophie, Mills, Ian G, Honeychurch, Jamie, Illidge, Tim M · 2023 · Oncoimmunology · DOI

Full title: Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1.

Authors: Mukherjee, Debayan, Romano, Erminia, Walshaw, Richard, Zeef, Leo A H, Banyard, Antonia, Kitcatt, Stephen J, Cheadle, Eleanor J, Tuomela, Karoliina, Pendharkar, Swati, Al-Deka, Aws, Salerno, Beatrice, Raby, Sophie, Mills, Ian G, Honeychurch, Jamie, Illidge, Tim M

Year: 2023

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2023.2223094

Paper Immunotherapy for resectable lung cancer

Dennehy, Colum, Conroy, Michael R., Forde, Patrick M. · 2025 · Cancer · DOI

Full title: Immunotherapy for resectable lung cancer

Authors: Dennehy, Colum, Conroy, Michael R., Forde, Patrick M.

Year: 2025

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.35849

Paper Improving the Cost Efficiency of PD-1/PD-L1 Inhibitors for Advanced Urothelial Carcinoma: A Major Role for Precision Medicine?

Sonpavde, Guru, Dranitsaris, George, Necchi, Andrea · 2018 · European urology · DOI

Full title: Improving the Cost Efficiency of PD-1/PD-L1 Inhibitors for Advanced Urothelial Carcinoma: A Major Role for Precision Medicine?

Authors: Sonpavde, Guru, Dranitsaris, George, Necchi, Andrea

Year: 2018

Venue: European urology

DOI: https://doi.org/10.1016/j.eururo.2018.03.015

Paper Therapeutic use of anti-CTLA-4 antibodies.

Blank, Christian U, Enk, Alexander · 2015 · International immunology · DOI

Full title: Therapeutic use of anti-CTLA-4 antibodies.

Authors: Blank, Christian U, Enk, Alexander

Year: 2015

Venue: International immunology

DOI: https://doi.org/10.1093/intimm/dxu076

Paper Effect of sex on the efficacy of patients receiving immune checkpoint inhibitors in advanced non-small cell lung cancer.

Wang, Chengdi, Qiao, Wenliang, Jiang, Yuting, Zhu, Min, Shao, Jun, Ren, Pengwei, Liu, Dan, Li, Weimin · 2019 · Cancer medicine · DOI

Full title: Effect of sex on the efficacy of patients receiving immune checkpoint inhibitors in advanced non-small cell lung cancer.

Authors: Wang, Chengdi, Qiao, Wenliang, Jiang, Yuting, Zhu, Min, Shao, Jun, Ren, Pengwei, Liu, Dan, Li, Weimin

Year: 2019

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.2280

Paper DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Mullen, Nicholas J., Shukla, Surendra K., Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina V., LaBreck, Drew A., Mallareddy, Jayapal Reddy, Price, David H., Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B., Hollingsworth, Michael A., Singh, Pankaj K. · 2023 · DOI

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: Mullen, Nicholas J., Shukla, Surendra K., Thakur, Ravi, Kollala, Sai Sundeep, Wang, Dezhen, Chaika, Nina V., LaBreck, Drew A., Mallareddy, Jayapal Reddy, Price, David H., Natarajan, Amarnath, Mehla, Kamiya, Sykes, David B., Hollingsworth, Michael A., Singh, Pankaj K.

Year: 2023

DOI: https://doi.org/10.7554/elife.87292.1

Paper Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient.

Herz, Saskia, Höfer, Thomas, Papapanagiotou, Matina, Leyh, Julia Christina, Meyenburg, Sarah, Schadendorf, Dirk, Ugurel, Selma, Roesch, Alexander, Livingstone, Elisabeth, Schilling, Bastian, Franklin, Cindy · 2016 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient.

Authors: Herz, Saskia, Höfer, Thomas, Papapanagiotou, Matina, Leyh, Julia Christina, Meyenburg, Sarah, Schadendorf, Dirk, Ugurel, Selma, Roesch, Alexander, Livingstone, Elisabeth, Schilling, Bastian, Franklin, Cindy

Year: 2016

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2016.07.026

Paper PD-1/PD-L1 immune checkpoint inhibitors in glioblastoma: clinical studies, challenges and potential

Yang, Tianrui, Kong, Ziren, Ma, Wenbin · 2020 · Human Vaccines & Immunotherapeutics · DOI

Full title: PD-1/PD-L1 immune checkpoint inhibitors in glioblastoma: clinical studies, challenges and potential

Authors: Yang, Tianrui, Kong, Ziren, Ma, Wenbin

Year: 2020

Venue: Human Vaccines & Immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2020.1782692

Paper In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.

Clark, Paul A, Sriramaneni, Raghava N, Jin, Won Jong, Jagodinsky, Justin C, Bates, Amber M, Jaquish, Abigail A, Anderson, Bryce R, Le, Trang, Lubin, Jonathan A, Chakravarty, Ishan, Arthur, Ian S, Heinze, Clinton M, Guy, Emily I, Kler, Jasdeep, Klar, Kelsey A, Carlson, Peter M, Kim, Kyung Mann, Kuo, John S, Morris, Zachary S · 2020 · Journal for immunotherapy of cancer · DOI

Full title: In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.

Authors: Clark, Paul A, Sriramaneni, Raghava N, Jin, Won Jong, Jagodinsky, Justin C, Bates, Amber M, Jaquish, Abigail A, Anderson, Bryce R, Le, Trang, Lubin, Jonathan A, Chakravarty, Ishan, Arthur, Ian S, Heinze, Clinton M, Guy, Emily I, Kler, Jasdeep, Klar, Kelsey A, Carlson, Peter M, Kim, Kyung Mann, Kuo, John S, Morris, Zachary S

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-000809

Paper Iparomlimab and Tuvonralimab: First Approval.

Keam, Susan J · 2025 · Drugs · DOI

Full title: Iparomlimab and Tuvonralimab: First Approval.

Authors: Keam, Susan J

Year: 2025

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-025-02160-6

Paper Bifidobacterium can mitigate intestinal immunopathology in the context of CTLA-4 blockade.

Wang, Feng, Yin, Qian, Chen, Liang, Davis, Mark M · 2018 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Bifidobacterium can mitigate intestinal immunopathology in the context of CTLA-4 blockade.

Authors: Wang, Feng, Yin, Qian, Chen, Liang, Davis, Mark M

Year: 2018

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1712901115

Paper Combination Strategies on the Basis of Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer: Where Do We Stand?

Qiao, Meng, Jiang, Tao, Ren, Shengxiang, Zhou, Caicun · 2018 · Clinical lung cancer · DOI

Full title: Combination Strategies on the Basis of Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer: Where Do We Stand?

Authors: Qiao, Meng, Jiang, Tao, Ren, Shengxiang, Zhou, Caicun

Year: 2018

Venue: Clinical lung cancer

DOI: https://doi.org/10.1016/j.cllc.2017.06.005

Paper Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy.

Chen, Jiang, Amoozgar, Zohreh, Liu, Xin, Aoki, Shuichi, Liu, Zelong, Shin, Sarah M, Matsui, Aya, Hernandez, Alexei, Pu, Zhangya, Halvorsen, Stefan, Lei, Pin-Ji, Datta, Meenal, Zhu, Lingling, Ruan, Zhiping, Shi, Lei, Staiculescu, Daniel, Inoue, Koetsu, Munn, Lance L, Fukumura, Dai, Huang, Peigen, Sassi, Slim, Bardeesy, Nabeel, Ho, Won Jin, Jain, Rakesh K, Duda, Dan G · 2024 · Cancer immunology research · DOI

Full title: Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy.

Authors: Chen, Jiang, Amoozgar, Zohreh, Liu, Xin, Aoki, Shuichi, Liu, Zelong, Shin, Sarah M, Matsui, Aya, Hernandez, Alexei, Pu, Zhangya, Halvorsen, Stefan, Lei, Pin-Ji, Datta, Meenal, Zhu, Lingling, Ruan, Zhiping, Shi, Lei, Staiculescu, Daniel, Inoue, Koetsu, Munn, Lance L, Fukumura, Dai, Huang, Peigen, Sassi, Slim, Bardeesy, Nabeel, Ho, Won Jin, Jain, Rakesh K, Duda, Dan G

Year: 2024

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-23-0486

Paper Application of Immune Checkpoint Inhibitors in Gynecological Cancers: What Do Gynecologists Need to Know before Using Immune Checkpoint Inhibitors?

Lee, Seon-Mi, Lee, Sanghoon, Cho, Hyun-Woong, Min, Kyung-Jin, Hong, Jin-Hwa, Song, Jae-Yun, Lee, Jae-Kwan, Lee, Nak-Woo · 2023 · International journal of molecular sciences · DOI

Full title: Application of Immune Checkpoint Inhibitors in Gynecological Cancers: What Do Gynecologists Need to Know before Using Immune Checkpoint Inhibitors?

Authors: Lee, Seon-Mi, Lee, Sanghoon, Cho, Hyun-Woong, Min, Kyung-Jin, Hong, Jin-Hwa, Song, Jae-Yun, Lee, Jae-Kwan, Lee, Nak-Woo

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24020974

Paper Adverse neurologic events of immune checkpoint inhibitor monotherapy vs. combination therapy for melanoma.

Das, Nikita, Dhamija, Ravi, Kaelber, David C, Kelly, Michael, Xie, Peter, Reddy, Deven · 2025 · Neuro-oncology advances · DOI

Full title: Adverse neurologic events of immune checkpoint inhibitor monotherapy vs. combination therapy for melanoma.

Authors: Das, Nikita, Dhamija, Ravi, Kaelber, David C, Kelly, Michael, Xie, Peter, Reddy, Deven

Year: 2025

Venue: Neuro-oncology advances

DOI: https://doi.org/10.1093/noajnl/vdaf030

Paper Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy

Kuai, Rui, Sun, Xiaoqi, Yuan, Wenmin, Xu, Yao, Schwendeman, Anna, Moon, James J. · 2018 · Bioconjugate Chemistry · DOI

Full title: Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy

Authors: Kuai, Rui, Sun, Xiaoqi, Yuan, Wenmin, Xu, Yao, Schwendeman, Anna, Moon, James J.

Year: 2018

Venue: Bioconjugate Chemistry

DOI: https://doi.org/10.1021/acs.bioconjchem.7b00761

Paper Pembrolizumab and other immune checkpoint inhibitors in locally advanced or metastatic Merkel Cell Carcinoma: safety and efficacy.

Marchand, Antoine, Kervarrec, Thibault, Bhatia, Shailender, Samimi, Mahtab · 2020 · Expert review of anticancer therapy · DOI

Full title: Pembrolizumab and other immune checkpoint inhibitors in locally advanced or metastatic Merkel Cell Carcinoma: safety and efficacy.

Authors: Marchand, Antoine, Kervarrec, Thibault, Bhatia, Shailender, Samimi, Mahtab

Year: 2020

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2021.1835477

Paper IMMU-19. EVALUATING EFFECTS OF REVERSING DISTINCT FACETS OF IMMUNOSUPPRESSION IN EXPERIMENTAL GBM

K. Ayasoufi, Zachariah P. Tritz, C. Fain, Roman H. Khadka, F. Jin, M. Hansen, Aaron J. Johnson · 2021 · Neuro-Oncology · DOI

Full title: IMMU-19. EVALUATING EFFECTS OF REVERSING DISTINCT FACETS OF IMMUNOSUPPRESSION IN EXPERIMENTAL GBM

Authors: K. Ayasoufi, Zachariah P. Tritz, C. Fain, Roman H. Khadka, F. Jin, M. Hansen, Aaron J. Johnson

Year: 2021

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noab196.378

Paper Case of anti-Zic4 antibody-mediated cerebellar toxicity induced by dual checkpoint inhibition in head and neck squamous cell carcinoma.

Iyer, Sunil Girish, Khakoo, Nidah Shabbir, Aitcheson, Gabriella, Perez, Cesar · 2020 · BMJ case reports · DOI

Full title: Case of anti-Zic4 antibody-mediated cerebellar toxicity induced by dual checkpoint inhibition in head and neck squamous cell carcinoma.

Authors: Iyer, Sunil Girish, Khakoo, Nidah Shabbir, Aitcheson, Gabriella, Perez, Cesar

Year: 2020

Venue: BMJ case reports

DOI: https://doi.org/10.1136/bcr-2020-235607

Paper Immunological Characteristics of Colitis Associated with Anti-CTLA-4 Antibody Therapy.

Bamias, Giorgos, Delladetsima, Ioanna, Perdiki, Marina, Siakavellas, Spyros I, Goukos, Dimitrios, Papatheodoridis, George V, Daikos, George L, Gogas, Helen · 2017 · Cancer investigation · DOI

Full title: Immunological Characteristics of Colitis Associated with Anti-CTLA-4 Antibody Therapy.

Authors: Bamias, Giorgos, Delladetsima, Ioanna, Perdiki, Marina, Siakavellas, Spyros I, Goukos, Dimitrios, Papatheodoridis, George V, Daikos, George L, Gogas, Helen

Year: 2017

Venue: Cancer investigation

DOI: https://doi.org/10.1080/07357907.2017.1324032

Paper Survival after neoadjuvant/induction combination immunotherapy vs combination platinum‐based chemotherapy for locally advanced (Stage III ) urothelial cancer

Einerhand, Sarah, Dijk, Nick van, Dorp, Jeroen van, Feijter, Jeantine M. de, Montfoort, Maurits L. van, Kamp, Maaike W. van de, Schaake, Eva E., Boellaard, Thierry N., Hendricksen, Kees, Heijden, Michiel S. van der, Rhijn, Bas W. G. van · 2022 · International Journal of Cancer · DOI

Full title: Survival after neoadjuvant/induction combination immunotherapy vs combination platinum‐based chemotherapy for locally advanced (Stage III ) urothelial cancer

Authors: Einerhand, Sarah, Dijk, Nick van, Dorp, Jeroen van, Feijter, Jeantine M. de, Montfoort, Maurits L. van, Kamp, Maaike W. van de, Schaake, Eva E., Boellaard, Thierry N., Hendricksen, Kees, Heijden, Michiel S. van der, Rhijn, Bas W. G. van

Year: 2022

Venue: International Journal of Cancer

DOI: https://doi.org/10.1002/ijc.34125

Paper TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti-CTLA4 treatment.

Li, Huahua, Li, Jia, Zhang, Chenyue, Zhang, Chenxing, Wang, Haiyong · 2020 · Cancer medicine · DOI

Full title: TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti-CTLA4 treatment.

Authors: Li, Huahua, Li, Jia, Zhang, Chenyue, Zhang, Chenxing, Wang, Haiyong

Year: 2020

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.3376

Paper Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Pai, Chien-Chun Steven, Huang, John T, Lu, Xiaoqing, Simons, Donald M, Park, Chanhyuk, Chang, Anthony, Tamaki, Whitney, Liu, Eric, Roybal, Kole T, Seagal, Jane, Chen, Mingyi, Hagihara, Katsunobu, Wei, Xiao X, DuPage, Michel, Kwek, Serena S, Oh, David Y, Daud, Adil, Tsai, Katy K, Wu, Clint, Zhang, Li, Fasso, Marcella, Sachidanandam, Ravi, Jayaprakash, Anitha, Lin, Ingrid, Casbon, Amy-Jo, Kinsbury, Gillian A, Fong, Lawrence · 2019 · Immunity · DOI

Full title: Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Authors: Pai, Chien-Chun Steven, Huang, John T, Lu, Xiaoqing, Simons, Donald M, Park, Chanhyuk, Chang, Anthony, Tamaki, Whitney, Liu, Eric, Roybal, Kole T, Seagal, Jane, Chen, Mingyi, Hagihara, Katsunobu, Wei, Xiao X, DuPage, Michel, Kwek, Serena S, Oh, David Y, Daud, Adil, Tsai, Katy K, Wu, Clint, Zhang, Li, Fasso, Marcella, Sachidanandam, Ravi, Jayaprakash, Anitha, Lin, Ingrid, Casbon, Amy-Jo, Kinsbury, Gillian A, Fong, Lawrence

Year: 2019

Venue: Immunity

DOI: https://doi.org/10.1016/j.immuni.2019.01.006

Paper Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunotherapy

Hazama, Shoichi, Tamada, Koji, Yamaguchi, Yoshiyuki, Kawakami, Yutaka, Nagano, Hiroaki · 2018 · Annals of Gastroenterological Surgery · DOI

Full title: Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunotherapy

Authors: Hazama, Shoichi, Tamada, Koji, Yamaguchi, Yoshiyuki, Kawakami, Yutaka, Nagano, Hiroaki

Year: 2018

Venue: Annals of Gastroenterological Surgery

DOI: https://doi.org/10.1002/ags3.12180

Paper Integrating Costimulatory Agonists to Optimize Immune-Based Cancer Therapies

Pardee, Angela D., Wesa, Amy, Storkus, Walter J. · 2009 · Immunotherapy · DOI

Full title: Integrating Costimulatory Agonists to Optimize Immune-Based Cancer Therapies

Authors: Pardee, Angela D., Wesa, Amy, Storkus, Walter J.

Year: 2009

Venue: Immunotherapy

DOI: https://doi.org/10.2217/1750743x.1.2.249

Paper The Immunosuppressive Microenvironment of Glioblastoma: Mechanisms, Clinical Challenges and Future Directions.

Pang, Changming, Wang, Yan · 2025 · Immunology · DOI

Full title: The Immunosuppressive Microenvironment of Glioblastoma: Mechanisms, Clinical Challenges and Future Directions.

Authors: Pang, Changming, Wang, Yan

Year: 2025

Venue: Immunology

DOI: https://doi.org/10.1111/imm.70087

Paper Durable response to combination immunotherapy using nivolumab and ipilimumab in metastatic succinate dehydrogenase (SDH)-deficient gastrointestinal stroma tumour.

Klein, Oliver, Palmer, Jodie, Behren, Andreas, Cebon, Jonathan, Kee, Damien · 2023 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Durable response to combination immunotherapy using nivolumab and ipilimumab in metastatic succinate dehydrogenase (SDH)-deficient gastrointestinal stroma tumour.

Authors: Klein, Oliver, Palmer, Jodie, Behren, Andreas, Cebon, Jonathan, Kee, Damien

Year: 2023

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2023.113351

Paper Phototherapy using immunologically modified carbon nanotubes to potentiate checkpoint blockade for metastatic breast cancer.

Li, Yong, Li, Xiaosong, Doughty, Austin, West, Connor, Wang, Lu, Zhou, Feifan, Nordquist, Robert E, Chen, Wei R · 2019 · Nanomedicine : nanotechnology, biology, and medicine · DOI

Full title: Phototherapy using immunologically modified carbon nanotubes to potentiate checkpoint blockade for metastatic breast cancer.

Authors: Li, Yong, Li, Xiaosong, Doughty, Austin, West, Connor, Wang, Lu, Zhou, Feifan, Nordquist, Robert E, Chen, Wei R

Year: 2019

Venue: Nanomedicine : nanotechnology, biology, and medicine

DOI: https://doi.org/10.1016/j.nano.2019.02.009

Paper Combined use of microwave ablation and cell immunotherapy induces nonspecific immunity of hepatocellular carcinoma model mice.

Duan, Xuhua, Wang, Manzhou, Han, Xinwei, Ren, Jianzhuang, Huang, Guohao, Ju, Shuguang, Zhang, Qinghui · 2020 · Cell cycle (Georgetown, Tex.) · DOI

Full title: Combined use of microwave ablation and cell immunotherapy induces nonspecific immunity of hepatocellular carcinoma model mice.

Authors: Duan, Xuhua, Wang, Manzhou, Han, Xinwei, Ren, Jianzhuang, Huang, Guohao, Ju, Shuguang, Zhang, Qinghui

Year: 2020

Venue: Cell cycle (Georgetown, Tex.)

DOI: https://doi.org/10.1080/15384101.2020.1853942

Paper [First line treatment of non-oncogene-addicted metastatic non-small cell lung cancer].

Gille, Romane, Pérol, Maurice · 2025 · Bulletin du cancer · DOI

Full title: [First line treatment of non-oncogene-addicted metastatic non-small cell lung cancer].

Authors: Gille, Romane, Pérol, Maurice

Year: 2025

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/S0007-4551(25)00159-6

Paper Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma.

Gao, Jianjun, Navai, Neema, Alhalabi, Omar, Siefker-Radtke, Arlene, Campbell, Matthew T, Tidwell, Rebecca Slack, Guo, Charles C, Kamat, Ashish M, Matin, Surena F, Araujo, John C, Shah, Amishi Y, Msaouel, Pavlos, Corn, Paul, Wang, Jianbo, Papadopoulos, John N, Yadav, Shalini S, Blando, Jorge M, Duan, Fei, Basu, Sreyashi, Liu, Wenbin, Shen, Yu, Zhang, Yuwei, Macaluso, Marc Daniel, Wang, Ying, Chen, Jianfeng, Zhang, Jianhua, Futreal, Andrew, Dinney, Colin, Allison, James P, Goswami, Sangeeta, Sharma, Padmanee · 2020 · Nature medicine · DOI

Full title: Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma.

Authors: Gao, Jianjun, Navai, Neema, Alhalabi, Omar, Siefker-Radtke, Arlene, Campbell, Matthew T, Tidwell, Rebecca Slack, Guo, Charles C, Kamat, Ashish M, Matin, Surena F, Araujo, John C, Shah, Amishi Y, Msaouel, Pavlos, Corn, Paul, Wang, Jianbo, Papadopoulos, John N, Yadav, Shalini S, Blando, Jorge M, Duan, Fei, Basu, Sreyashi, Liu, Wenbin, Shen, Yu, Zhang, Yuwei, Macaluso, Marc Daniel, Wang, Ying, Chen, Jianfeng, Zhang, Jianhua, Futreal, Andrew, Dinney, Colin, Allison, James P, Goswami, Sangeeta, Sharma, Padmanee

Year: 2020

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-020-1086-y

Paper Evaluation of TMB as a predictive biomarker in patients with solid cancers treated with anti-PD-1/CTLA-4 combination immunotherapy.

Klein, Oliver, Kee, Damien, Markman, Ben, Carlino, Matteo S, Underhill, Craig, Palmer, Jodie, Power, Daniel, Cebon, Jonathan, Behren, Andreas · 2021 · Cancer cell · DOI

Full title: Evaluation of TMB as a predictive biomarker in patients with solid cancers treated with anti-PD-1/CTLA-4 combination immunotherapy.

Authors: Klein, Oliver, Kee, Damien, Markman, Ben, Carlino, Matteo S, Underhill, Craig, Palmer, Jodie, Power, Daniel, Cebon, Jonathan, Behren, Andreas

Year: 2021

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2021.04.005

Paper Immune checkpoint inhibitor-associated pituitary adverse events: an observational, retrospective, disproportionality study.

Bai, X, Chen, X, Wu, X, Huang, Y, Zhuang, Y, Chen, Y, Feng, C, Lin, Xiahong · 2020 · Journal of endocrinological investigation · DOI

Full title: Immune checkpoint inhibitor-associated pituitary adverse events: an observational, retrospective, disproportionality study.

Authors: Bai, X, Chen, X, Wu, X, Huang, Y, Zhuang, Y, Chen, Y, Feng, C, Lin, Xiahong

Year: 2020

Venue: Journal of endocrinological investigation

DOI: https://doi.org/10.1007/s40618-020-01226-4

Paper Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

Horton, Brendan, Williams, Jason B., Cabanov, Alexandra, Spranger, Stefani, Gajewski, Thomas F. · 2017 · Cancer Immunology Research · DOI

Full title: Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

Authors: Horton, Brendan, Williams, Jason B., Cabanov, Alexandra, Spranger, Stefani, Gajewski, Thomas F.

Year: 2017

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-17-0249

Paper Indoleamine 2,3-dioxygenase (IDO) inhibitors and cancer immunotherapy.

Fujiwara, Yu, Kato, Shumei, Nesline, Mary K, Conroy, Jeffrey M, DePietro, Paul, Pabla, Sarabjot, Kurzrock, Razelle · 2022 · Cancer treatment reviews · DOI

Full title: Indoleamine 2,3-dioxygenase (IDO) inhibitors and cancer immunotherapy.

Authors: Fujiwara, Yu, Kato, Shumei, Nesline, Mary K, Conroy, Jeffrey M, DePietro, Paul, Pabla, Sarabjot, Kurzrock, Razelle

Year: 2022

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2022.102461

Paper Targeting CTLA-4 in cancer: Is it the ideal companion for PD-1 blockade immunotherapy combinations?

De Silva, Pushpamali, Aiello, Marco, Gu-Trantien, Chunyan, Migliori, Edoardo, Willard-Gallo, Karen, Solinas, Cinzia · 2021 · International journal of cancer · DOI

Full title: Targeting CTLA-4 in cancer: Is it the ideal companion for PD-1 blockade immunotherapy combinations?

Authors: De Silva, Pushpamali, Aiello, Marco, Gu-Trantien, Chunyan, Migliori, Edoardo, Willard-Gallo, Karen, Solinas, Cinzia

Year: 2021

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.33415

Paper Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors.

Parlati, Lucia, Sakka, Mehdi, Retbi, Aurelia, Bouam, Samir, Hassani, Lamia, Meritet, Jean-François, Rufat, Pierre, Bonnefont-Rousselot, Dominique, Batista, Rui, Terris, Benoit, Bellanger, Agnès, Thabut, Dominique, Vozy, Aurore, Spano, Jean-Philippe, Coriat, Romain, Goldwasser, François, Aractingi, Selim, Sogni, Philippe, Pol, Stanislas, Mallet, Vincent, CERTIM Research Group, DEMOSTHENES Research Group · 2023 · JHEP reports : innovation in hepatology · DOI

Full title: Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors.

Authors: Parlati, Lucia, Sakka, Mehdi, Retbi, Aurelia, Bouam, Samir, Hassani, Lamia, Meritet, Jean-François, Rufat, Pierre, Bonnefont-Rousselot, Dominique, Batista, Rui, Terris, Benoit, Bellanger, Agnès, Thabut, Dominique, Vozy, Aurore, Spano, Jean-Philippe, Coriat, Romain, Goldwasser, François, Aractingi, Selim, Sogni, Philippe, Pol, Stanislas, Mallet, Vincent, CERTIM Research Group, DEMOSTHENES Research Group

Year: 2023

Venue: JHEP reports : innovation in hepatology

DOI: https://doi.org/10.1016/j.jhepr.2023.100880

Paper High Antigenicity for Treg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in Treg Cells.

Matsuura, Hiroaki, Ishino, Takamasa, Ninomiya, Toshifumi, Ninomiya, Kiichiro, Tachibana, Kota, Honobe-Tabuchi, Akiko, Muto, Yoshinori, Inozume, Takashi, Ueda, Youki, Ohashi, Kadoaki, Maeda, Yoshinobu, Nagasaki, Joji, Togashi, Yosuke · 2025 · Cancer science · DOI

Full title: High Antigenicity for Treg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in Treg Cells.

Authors: Matsuura, Hiroaki, Ishino, Takamasa, Ninomiya, Toshifumi, Ninomiya, Kiichiro, Tachibana, Kota, Honobe-Tabuchi, Akiko, Muto, Yoshinori, Inozume, Takashi, Ueda, Youki, Ohashi, Kadoaki, Maeda, Yoshinobu, Nagasaki, Joji, Togashi, Yosuke

Year: 2025

Venue: Cancer science

DOI: https://doi.org/10.1111/cas.70029

Paper [Role of PD-1/PD-L1 in microenvironment of breast cancer].

Ji, P, Gong, Y, Hu, X · 2019 · Zhonghua zhong liu za zhi [Chinese journal of oncology] · DOI

Full title: [Role of PD-1/PD-L1 in microenvironment of breast cancer].

Authors: Ji, P, Gong, Y, Hu, X

Year: 2019

Venue: Zhonghua zhong liu za zhi [Chinese journal of oncology]

DOI: https://doi.org/10.3760/cma.j.issn.0253-3766.2019.06.001

Paper Basis for molecular diagnostics and immunotherapy for esophageal cancer.

Abdo, Joe, Agrawal, Devendra K, Mittal, Sumeet K · 2017 · Expert review of anticancer therapy · DOI

Full title: Basis for molecular diagnostics and immunotherapy for esophageal cancer.

Authors: Abdo, Joe, Agrawal, Devendra K, Mittal, Sumeet K

Year: 2017

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2017.1260449

Paper The MHC-I-dependent neoantigen presentation pathway predicts response rate to PD-1/PD-L1 blockade.

Zhang, Yuchen, Yang, Chen, Xu, Yanchao, Jiang, Xiang, Shi, Jiajun, Li, Binghua, Yu, Decai · 2025 · Biomolecules & biomedicine · DOI

Full title: The MHC-I-dependent neoantigen presentation pathway predicts response rate to PD-1/PD-L1 blockade.

Authors: Zhang, Yuchen, Yang, Chen, Xu, Yanchao, Jiang, Xiang, Shi, Jiajun, Li, Binghua, Yu, Decai

Year: 2025

Venue: Biomolecules & biomedicine

DOI: https://doi.org/10.17305/bb.2024.11069

Paper Checkpoint Inhibitors for the Treatment of Renal Cell Carcinoma.

Ghatalia, Pooja, Zibelman, Matthew, Geynisman, Daniel M, Plimack, Elizabeth R · 2017 · Current treatment options in oncology · DOI

Full title: Checkpoint Inhibitors for the Treatment of Renal Cell Carcinoma.

Authors: Ghatalia, Pooja, Zibelman, Matthew, Geynisman, Daniel M, Plimack, Elizabeth R

Year: 2017

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-017-0458-0

Paper Combining Vaccines with Conventional Therapies for Cancer.

Arlen, Philip M, Madan, Ravi A, Hodge, James W, Schlom, Jeffrey, Gulley, James L · 2007 · Update on cancer therapeutics · DOI

Full title: Combining Vaccines with Conventional Therapies for Cancer.

Authors: Arlen, Philip M, Madan, Ravi A, Hodge, James W, Schlom, Jeffrey, Gulley, James L

Year: 2007

Venue: Update on cancer therapeutics

DOI: https://doi.org/10.1016/j.uct.2007.04.004

Paper Systematic Assessment of Risk of Fever in Solid Tumor Patients Treated With PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Liu, Hongmei, Xu, Dongmei, Wang, Wentao, Sun, Fengchao, Zhang, Shuisheng, Yang, Xiaowei, Tian, Yuan · 2020 · Frontiers in oncology · DOI

Full title: Systematic Assessment of Risk of Fever in Solid Tumor Patients Treated With PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Authors: Liu, Hongmei, Xu, Dongmei, Wang, Wentao, Sun, Fengchao, Zhang, Shuisheng, Yang, Xiaowei, Tian, Yuan

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.570080

Paper Importance of IL-10 for CTLA-4-mediated inhibition of tumor-eradicating immunity.

Jovasevic, Vladimir M, Gorelik, Leonid, Bluestone, Jeffrey A, Mokyr, Margalit B · 2004 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Importance of IL-10 for CTLA-4-mediated inhibition of tumor-eradicating immunity.

Authors: Jovasevic, Vladimir M, Gorelik, Leonid, Bluestone, Jeffrey A, Mokyr, Margalit B

Year: 2004

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.172.3.1449

Paper RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.

Heidegger, Simon, Kreppel, Diana, Bscheider, Michael, Stritzke, Florian, Nedelko, Tatiana, Wintges, Alexander, Bek, Sarah, Fischer, Julius C, Graalmann, Theresa, Kalinke, Ulrich, Bassermann, Florian, Haas, Tobias, Poeck, Hendrik · 2019 · EBioMedicine · DOI

Full title: RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.

Authors: Heidegger, Simon, Kreppel, Diana, Bscheider, Michael, Stritzke, Florian, Nedelko, Tatiana, Wintges, Alexander, Bek, Sarah, Fischer, Julius C, Graalmann, Theresa, Kalinke, Ulrich, Bassermann, Florian, Haas, Tobias, Poeck, Hendrik

Year: 2019

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2019.02.056

Paper A Systematic Review of Immunotherapy in Urologic Cancer: Evolving Roles for Targeting of CTLA-4, PD-1/PD-L1, and HLA-G.

Carosella, Edgardo D, Ploussard, Guillaume, LeMaoult, Joel, Desgrandchamps, Francois · 2015 · European urology · DOI

Full title: A Systematic Review of Immunotherapy in Urologic Cancer: Evolving Roles for Targeting of CTLA-4, PD-1/PD-L1, and HLA-G.

Authors: Carosella, Edgardo D, Ploussard, Guillaume, LeMaoult, Joel, Desgrandchamps, Francois

Year: 2015

Venue: European urology

DOI: https://doi.org/10.1016/j.eururo.2015.02.032

Paper A major responder to ipilimumab and nivolumab in metastatic uveal melanoma with concomitant autoimmunity

Chan, Pui Ying, Hall, Peter E., Hay, Gordon, Cohen, Victoria M.L., Szlosarek, Peter W. · 2017 · Pigment Cell & Melanoma Research · DOI

Full title: A major responder to ipilimumab and nivolumab in metastatic uveal melanoma with concomitant autoimmunity

Authors: Chan, Pui Ying, Hall, Peter E., Hay, Gordon, Cohen, Victoria M.L., Szlosarek, Peter W.

Year: 2017

Venue: Pigment Cell & Melanoma Research

DOI: https://doi.org/10.1111/pcmr.12607

Paper Pembrolizumab versus Ipilimumab in Advanced Melanoma

Robert, Caroline, Schachter, Jacob, Long, Georgina V., Arance, Ana, Grob, Jean‐Jacques, Mortier, Laurent, Daud, Adil, Carlino, Matteo S., McNeil, Catriona M., Lotem, Michal, Larkin, James, Lorigan, Paul, Neyns, Bart, Blank, Christian U., Hamid, Omid, Mateus, Christine, Shapira‐Frommer, Ronnie, Kosh, Michele, Zhou, Haiyu, Ibrahim, Nageatte, Ebbinghaus, Scot, Ribas, Antoni · 2015 · New England Journal of Medicine · DOI

Full title: Pembrolizumab versus Ipilimumab in Advanced Melanoma

Authors: Robert, Caroline, Schachter, Jacob, Long, Georgina V., Arance, Ana, Grob, Jean‐Jacques, Mortier, Laurent, Daud, Adil, Carlino, Matteo S., McNeil, Catriona M., Lotem, Michal, Larkin, James, Lorigan, Paul, Neyns, Bart, Blank, Christian U., Hamid, Omid, Mateus, Christine, Shapira‐Frommer, Ronnie, Kosh, Michele, Zhou, Haiyu, Ibrahim, Nageatte, Ebbinghaus, Scot, Ribas, Antoni

Year: 2015

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1503093

Paper Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report.

Langan, Ewan A, Budner, Kaja, Zillikens, Detlef, Terheyden, Patrick · 2021 · Medicine · DOI

Full title: Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report.

Authors: Langan, Ewan A, Budner, Kaja, Zillikens, Detlef, Terheyden, Patrick

Year: 2021

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000025513

Paper Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.

Fabian, Kellsye Paula L, Chi-Sabins, Nina, Taylor, Jennifer L, Fecek, Ronald, Weinstein, Aliyah, Storkus, Walter J · 2017 · Oncoimmunology · DOI

Full title: Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.

Authors: Fabian, Kellsye Paula L, Chi-Sabins, Nina, Taylor, Jennifer L, Fecek, Ronald, Weinstein, Aliyah, Storkus, Walter J

Year: 2017

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2017.1290035

Paper Targeted Therapies Combined With Immune Checkpoint Therapy.

Prieto, Peter A, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A · 2016 · Cancer journal (Sudbury, Mass.) · DOI

Full title: Targeted Therapies Combined With Immune Checkpoint Therapy.

Authors: Prieto, Peter A, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A

Year: 2016

Venue: Cancer journal (Sudbury, Mass.)

DOI: https://doi.org/10.1097/PPO.0000000000000182

Paper Emerging Strategies in Systemic Therapy for the Treatment of Melanoma.

Ascierto, Paolo A, Flaherty, Keith, Goff, Stephanie · 2018 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Emerging Strategies in Systemic Therapy for the Treatment of Melanoma.

Authors: Ascierto, Paolo A, Flaherty, Keith, Goff, Stephanie

Year: 2018

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.1200/EDBK_199047

Paper Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibitors in real-world head and neck and lung cancer patients.

Foy, Jean-Philippe, Karabajakian, Andy, Ortiz-Cuaran, Sandra, Boussageon, Maxime, Michon, Lucas, Bouaoud, Jebrane, Fekiri, Dorssafe, Robert, Marie, Baffert, Kim-Arthur, Hervé, Geneviève, Quilhot, Pauline, Attignon, Valéry, Girod, Angélique, Chaine, André, Benassarou, Mourad, Zrounba, Philippe, Caux, Christophe, Ghiringhelli, François, Lantuejoul, Sylvie, Crozes, Carole, Brochériou, Isabelle, Pérol, Maurice, Fayette, Jérôme, Bertolus, Chloé, Saintigny, Pierre · 2022 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibitors in real-world head and neck and lung cancer patients.

Authors: Foy, Jean-Philippe, Karabajakian, Andy, Ortiz-Cuaran, Sandra, Boussageon, Maxime, Michon, Lucas, Bouaoud, Jebrane, Fekiri, Dorssafe, Robert, Marie, Baffert, Kim-Arthur, Hervé, Geneviève, Quilhot, Pauline, Attignon, Valéry, Girod, Angélique, Chaine, André, Benassarou, Mourad, Zrounba, Philippe, Caux, Christophe, Ghiringhelli, François, Lantuejoul, Sylvie, Crozes, Carole, Brochériou, Isabelle, Pérol, Maurice, Fayette, Jérôme, Bertolus, Chloé, Saintigny, Pierre

Year: 2022

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2022.06.034

Paper Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.

Dos Santos, Luara Isabela, Galvão-Filho, Bruno, de Faria, Paula Cristina, Junqueira, Caroline, Dutra, Miriam Santos, Teixeira, Santuza Maria Ribeiro, Rodrigues, Maurício Martins, Ritter, Gerd, Bannard, Oliver, Fearon, Douglas Thomas, Antonelli, Lis Ribeiro, Gazzinelli, Ricardo Tostes · 2015 · Cancer immunology, immunotherapy : CII · DOI

Full title: Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.

Authors: Dos Santos, Luara Isabela, Galvão-Filho, Bruno, de Faria, Paula Cristina, Junqueira, Caroline, Dutra, Miriam Santos, Teixeira, Santuza Maria Ribeiro, Rodrigues, Maurício Martins, Ritter, Gerd, Bannard, Oliver, Fearon, Douglas Thomas, Antonelli, Lis Ribeiro, Gazzinelli, Ricardo Tostes

Year: 2015

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-014-1634-8

Paper Bone metastases treated with immune checkpoint inhibitors: A single center experience.

Grover, Punita, Karivedu, Vidhya, Zhu, Zheng, Jandarov, Roman, Wise‐Draper, Trisha M. · 2019 · Journal of Clinical Oncology · DOI

Full title: Bone metastases treated with immune checkpoint inhibitors: A single center experience.

Authors: Grover, Punita, Karivedu, Vidhya, Zhu, Zheng, Jandarov, Roman, Wise‐Draper, Trisha M.

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.e14105

Paper Microbiota-dependent activation of CD4+ T cells induces CTLA-4 blockade-associated colitis via Fcγ receptors.

Lo, Bernard C, Kryczek, Ilona, Yu, Jiali, Vatan, Linda, Caruso, Roberta, Matsumoto, Masanori, Sato, Yosuke, Shaw, Michael H, Inohara, Naohiro, Xie, Yuying, Lei, Yu Leo, Zou, Weiping, Núñez, Gabriel · 2024 · Science (New York, N.Y.) · DOI

Full title: Microbiota-dependent activation of CD4+ T cells induces CTLA-4 blockade-associated colitis via Fcγ receptors.

Authors: Lo, Bernard C, Kryczek, Ilona, Yu, Jiali, Vatan, Linda, Caruso, Roberta, Matsumoto, Masanori, Sato, Yosuke, Shaw, Michael H, Inohara, Naohiro, Xie, Yuying, Lei, Yu Leo, Zou, Weiping, Núñez, Gabriel

Year: 2024

Venue: Science (New York, N.Y.)

DOI: https://doi.org/10.1126/science.adh8342

Paper Immune Checkpoint Inhibitor Toxicity.

Palmieri, David J, Carlino, Matteo S · 2018 · Current oncology reports · DOI

Full title: Immune Checkpoint Inhibitor Toxicity.

Authors: Palmieri, David J, Carlino, Matteo S

Year: 2018

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-018-0718-6

Paper [Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor].

Muto, Yusuke, Kitano, Shigehisa · 2019 · Gan to kagaku ryoho. Cancer & chemotherapy

Full title: [Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor].

Authors: Muto, Yusuke, Kitano, Shigehisa

Year: 2019

Venue: Gan to kagaku ryoho. Cancer & chemotherapy

Paper [Immuno-oncology--silver bullets or mass destruction weapons?].

Utriainen, Meri, Rämet, Mika · 2016 · Duodecim; laaketieteellinen aikakauskirja

Full title: [Immuno-oncology--silver bullets or mass destruction weapons?].

Authors: Utriainen, Meri, Rämet, Mika

Year: 2016

Venue: Duodecim; laaketieteellinen aikakauskirja

Paper The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer

Patrinely, James R., Dewan, Anna K., Johnson, Douglas B. · 2020 · BioDrugs · DOI

Full title: The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer

Authors: Patrinely, James R., Dewan, Anna K., Johnson, Douglas B.

Year: 2020

Venue: BioDrugs

DOI: https://doi.org/10.1007/s40259-020-00428-9

Paper Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment

Passiglia, Francesco, Caglevic, Christian, Giovannetti, Elisa, Pinto, Joseph A., Manca, Paolo, Taverna, Simona, Listì, Angela, Gil‐Bazo, Ignacio, Raez, L., Russo, Antonio, Rolfo, Christian · 2018 · Seminars in Cancer Biology · DOI

Full title: Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment

Authors: Passiglia, Francesco, Caglevic, Christian, Giovannetti, Elisa, Pinto, Joseph A., Manca, Paolo, Taverna, Simona, Listì, Angela, Gil‐Bazo, Ignacio, Raez, L., Russo, Antonio, Rolfo, Christian

Year: 2018

Venue: Seminars in Cancer Biology

DOI: https://doi.org/10.1016/j.semcancer.2018.01.015

Paper Spectrum of Clinical Presentations, Imaging Findings, and HLA Types in Immune Checkpoint Inhibitor-Induced Hypophysitis.

Quandt, Zoe, Kim, Stephanie, Villanueva-Meyer, Javier, Coupe, Catherine, Young, Arabella, Kang, Jee Hye, Yazdany, Jinoos, Schmajuk, Gabriela, Rush, Stephanie, Ziv, Elad, Perdigoto, Ana Luisa, Herold, Kevan, Lechner, Melissa G, Su, Maureen A, Tyrrell, J Blake, Bluestone, Jeffrey, Anderson, Mark, Masharani, Umesh · 2023 · Journal of the Endocrine Society · DOI

Full title: Spectrum of Clinical Presentations, Imaging Findings, and HLA Types in Immune Checkpoint Inhibitor-Induced Hypophysitis.

Authors: Quandt, Zoe, Kim, Stephanie, Villanueva-Meyer, Javier, Coupe, Catherine, Young, Arabella, Kang, Jee Hye, Yazdany, Jinoos, Schmajuk, Gabriela, Rush, Stephanie, Ziv, Elad, Perdigoto, Ana Luisa, Herold, Kevan, Lechner, Melissa G, Su, Maureen A, Tyrrell, J Blake, Bluestone, Jeffrey, Anderson, Mark, Masharani, Umesh

Year: 2023

Venue: Journal of the Endocrine Society

DOI: https://doi.org/10.1210/jendso/bvad012

Paper 42 Intravital multiphoton microscopy of infiltrating T cell and tumor cell metabolism in a murine melanoma model

A. Heaton, Tiffany M. Heaster, A. Hoefges, A. Rakhmilevich, Amy K. Erbe, P. Sondel, M. Skala · 2020 · DOI

Full title: 42 Intravital multiphoton microscopy of infiltrating T cell and tumor cell metabolism in a murine melanoma model

Authors: A. Heaton, Tiffany M. Heaster, A. Hoefges, A. Rakhmilevich, Amy K. Erbe, P. Sondel, M. Skala

Year: 2020

DOI: https://doi.org/10.1136/jitc-2020-sitc2020.0042

Paper Advances in immunotherapy for hepatocellular carcinoma

Sangro, Bruno, Sarobe, Pablo, Hervás‐Stubbs, Sandra, Melero, Ignacio · 2021 · Nature Reviews Gastroenterology & Hepatology · DOI

Full title: Advances in immunotherapy for hepatocellular carcinoma

Authors: Sangro, Bruno, Sarobe, Pablo, Hervás‐Stubbs, Sandra, Melero, Ignacio

Year: 2021

Venue: Nature Reviews Gastroenterology & Hepatology

DOI: https://doi.org/10.1038/s41575-021-00438-0

Paper The Use of Combination Immunotherapies as Front-Line Therapy for Non-Small-Cell Lung Cancer

Santana-Dávila, Rafael, Chow, Laura QM · 2018 · Future Oncology · DOI

Full title: The Use of Combination Immunotherapies as Front-Line Therapy for Non-Small-Cell Lung Cancer

Authors: Santana-Dávila, Rafael, Chow, Laura QM

Year: 2018

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2017-0124

Paper Immune checkpoint inhibitors in advanced or metastatic mucosal melanoma: a systematic review.

Li, Jiarui, Kan, Haoxuan, Zhao, Lin, Sun, Zhao, Bai, Chunmei · 2020 · Therapeutic advances in medical oncology · DOI

Full title: Immune checkpoint inhibitors in advanced or metastatic mucosal melanoma: a systematic review.

Authors: Li, Jiarui, Kan, Haoxuan, Zhao, Lin, Sun, Zhao, Bai, Chunmei

Year: 2020

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758835920922028

Paper The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade.

Okoye, Isobel S, Xu, Lai, Walker, John, Elahi, Shokrollah · 2020 · Cancer immunology, immunotherapy : CII · DOI

Full title: The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade.

Authors: Okoye, Isobel S, Xu, Lai, Walker, John, Elahi, Shokrollah

Year: 2020

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02555-2

Paper Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable.

Namai, Fu, Murakami, Aito, Ueda, Asami, Tsukagoshi, Masami, Shigemori, Suguru, Ogita, Tasuku, Sato, Takashi, Shimosato, Takeshi · 2020 · Molecular biotechnology · DOI

Full title: Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable.

Authors: Namai, Fu, Murakami, Aito, Ueda, Asami, Tsukagoshi, Masami, Shigemori, Suguru, Ogita, Tasuku, Sato, Takashi, Shimosato, Takeshi

Year: 2020

Venue: Molecular biotechnology

DOI: https://doi.org/10.1007/s12033-020-00274-8

Paper VISTA Targeting of T-cell Quiescence and Myeloid Suppression Overcomes Adaptive Resistance.

Schaafsma, Evelien, Croteau, Walburga, ElTanbouly, Mohamed, Nowak, Elizabeth C, Smits, Nicole C, Deng, Jie, Sarde, Aurelien, Webber, Cecilia A, Rabadi, Dina, Cheng, Chao, Noelle, Randolph, Lines, J Louise · 2023 · Cancer immunology research · DOI

Full title: VISTA Targeting of T-cell Quiescence and Myeloid Suppression Overcomes Adaptive Resistance.

Authors: Schaafsma, Evelien, Croteau, Walburga, ElTanbouly, Mohamed, Nowak, Elizabeth C, Smits, Nicole C, Deng, Jie, Sarde, Aurelien, Webber, Cecilia A, Rabadi, Dina, Cheng, Chao, Noelle, Randolph, Lines, J Louise

Year: 2023

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-22-0116

Paper Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME.

Benmebarek, Mohamed-Reda, Oguz, Cihan, Seifert, Matthias, Ruf, Benjamin, Myojin, Yuta, Bauer, Kylynda C, Huang, Patrick, Ma, Chi, Villamor-Payà, Marina, Rodriguez-Matos, Francisco, Soliman, Marlaine, Trehan, Rajiv, Monge, Cecilia, Xie, Changqing, Kleiner, David E, Wood, Bradford J, Levy, Elliot B, Budhu, Anuradha, Kedei, Noemi, Mayer, Christian T, Wang, Xin Wei, Lack, Justin, Telford, William, Korangy, Firouzeh, Greten, Tim F · 2025 · Immunity · DOI

Full title: Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME.

Authors: Benmebarek, Mohamed-Reda, Oguz, Cihan, Seifert, Matthias, Ruf, Benjamin, Myojin, Yuta, Bauer, Kylynda C, Huang, Patrick, Ma, Chi, Villamor-Payà, Marina, Rodriguez-Matos, Francisco, Soliman, Marlaine, Trehan, Rajiv, Monge, Cecilia, Xie, Changqing, Kleiner, David E, Wood, Bradford J, Levy, Elliot B, Budhu, Anuradha, Kedei, Noemi, Mayer, Christian T, Wang, Xin Wei, Lack, Justin, Telford, William, Korangy, Firouzeh, Greten, Tim F

Year: 2025

Venue: Immunity

DOI: https://doi.org/10.1016/j.immuni.2025.02.017

Paper Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients.

Grynberg, Shirly, Stoff, Ronen, Asher, Nethanel, Shapira-Frommer, Ronnie, Schachter, Jacob, Haisraely, Ory, Lawrence, Yaacov, Ben-Betzalel, Guy · 2022 · Therapeutic advances in medical oncology · DOI

Full title: Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients.

Authors: Grynberg, Shirly, Stoff, Ronen, Asher, Nethanel, Shapira-Frommer, Ronnie, Schachter, Jacob, Haisraely, Ory, Lawrence, Yaacov, Ben-Betzalel, Guy

Year: 2022

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359221131521

Paper LAG-3 : recent developments in combinational therapies in cancer.

Chavanton, Aude, Mialhe, Flavie, Abrey, Jimena, Baeza Garcia, Alvaro, Garrido, Carmen · 2024 · Cancer science · DOI

Full title: LAG-3 : recent developments in combinational therapies in cancer.

Authors: Chavanton, Aude, Mialhe, Flavie, Abrey, Jimena, Baeza Garcia, Alvaro, Garrido, Carmen

Year: 2024

Venue: Cancer science

DOI: https://doi.org/10.1111/cas.16205

Paper Tumor immunologic heterogeneity influences response to radiation and combination immunotherapy

Aguilera, Todd A., Rafat, Marjan, Kariolis, Mihalis S., Eyben, Rie von, Graves, Edward E., Giaccia, Amato J. · 2015 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Tumor immunologic heterogeneity influences response to radiation and combination immunotherapy

Authors: Aguilera, Todd A., Rafat, Marjan, Kariolis, Mihalis S., Eyben, Rie von, Graves, Edward E., Giaccia, Amato J.

Year: 2015

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/2051-1426-3-s2-p345

Paper Metastatic Merkel cell carcinoma response to nivolumab.

Walocko, Frances M, Scheier, Benjamin Y, Harms, Paul W, Fecher, Leslie A, Lao, Christopher D · 2016 · Journal for immunotherapy of cancer · DOI

Full title: Metastatic Merkel cell carcinoma response to nivolumab.

Authors: Walocko, Frances M, Scheier, Benjamin Y, Harms, Paul W, Fecher, Leslie A, Lao, Christopher D

Year: 2016

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-016-0186-1

Paper Managing immune checkpoint-blocking antibody side effects.

Postow, Michael A · 2015 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Managing immune checkpoint-blocking antibody side effects.

Authors: Postow, Michael A

Year: 2015

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.14694/EdBook_AM.2015.35.76

Paper Neuron - specific enolase predicts the prognosis in advanced small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors.

Li, Lingling, Zhang, Zhibo, Hu, Yi · 2021 · Medicine · DOI

Full title: Neuron - specific enolase predicts the prognosis in advanced small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors.

Authors: Li, Lingling, Zhang, Zhibo, Hu, Yi

Year: 2021

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000027029

Paper Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors.

De Martin, Eleonora, Michot, Jean-Marie, Papouin, Barbara, Champiat, Stéphane, Mateus, Christine, Lambotte, Olivier, Roche, Bruno, Antonini, Teresa Maria, Coilly, Audrey, Laghouati, Salim, Robert, Caroline, Marabelle, Aurélien, Guettier, Catherine, Samuel, Didier · 2018 · Journal of hepatology · DOI

Full title: Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors.

Authors: De Martin, Eleonora, Michot, Jean-Marie, Papouin, Barbara, Champiat, Stéphane, Mateus, Christine, Lambotte, Olivier, Roche, Bruno, Antonini, Teresa Maria, Coilly, Audrey, Laghouati, Salim, Robert, Caroline, Marabelle, Aurélien, Guettier, Catherine, Samuel, Didier

Year: 2018

Venue: Journal of hepatology

DOI: https://doi.org/10.1016/j.jhep.2018.01.033

Paper Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.

Chen, Jiangbin, Tan, Qi, Yang, Zimo, Chen, Wenjuan, Zhou, E, Li, Minglei, Deng, Jingjing, Wu, Yali, Liu, Jiatong, Xu, Juanjuan, Guo, Mengfei, Jin, Yang · 2025 · Journal of extracellular vesicles · DOI

Full title: Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.

Authors: Chen, Jiangbin, Tan, Qi, Yang, Zimo, Chen, Wenjuan, Zhou, E, Li, Minglei, Deng, Jingjing, Wu, Yali, Liu, Jiatong, Xu, Juanjuan, Guo, Mengfei, Jin, Yang

Year: 2025

Venue: Journal of extracellular vesicles

DOI: https://doi.org/10.1002/jev2.70068

Paper Abstract 3778: Combination immunotherapy intercepts murine pancreatic cancer progression

A. Popovic, Nina J. Chu, T. Armstrong, E. Jaffee · 2018 · Immunology · DOI

Full title: Abstract 3778: Combination immunotherapy intercepts murine pancreatic cancer progression

Authors: A. Popovic, Nina J. Chu, T. Armstrong, E. Jaffee

Year: 2018

Venue: Immunology

DOI: https://doi.org/10.1158/1538-7445.am2018-3778

Paper Immune checkpoint modulation for non-small cell lung cancer.

Soria, Jean-Charles, Marabelle, Aurélien, Brahmer, Julie R, Gettinger, Scott · 2015 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Immune checkpoint modulation for non-small cell lung cancer.

Authors: Soria, Jean-Charles, Marabelle, Aurélien, Brahmer, Julie R, Gettinger, Scott

Year: 2015

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-14-2959

Paper PD-1 and CTLA-4 inhibitors in combination vs. alone for the treatment of advanced melanoma: A systematic review and meta-analysis.

He, Runzhi, Zhao, Xiaoling, Liu, Jianmin, Zhou, Yajing, Zhang, Xiaochong, Cheng, Fang · 2022 · Medicine · DOI

Full title: PD-1 and CTLA-4 inhibitors in combination vs. alone for the treatment of advanced melanoma: A systematic review and meta-analysis.

Authors: He, Runzhi, Zhao, Xiaoling, Liu, Jianmin, Zhou, Yajing, Zhang, Xiaochong, Cheng, Fang

Year: 2022

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000030561

Paper Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting.

Aggen, David H, Drake, Charles G, Rini, Brian I · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting.

Authors: Aggen, David H, Drake, Charles G, Rini, Brian I

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-19-3323

Paper Combination of CTLA-4 blockade with MUC1 mRNA nanovaccine induces enhanced anti-tumor CTL activity by modulating tumor microenvironment of triple negative breast cancer

Lin, Xuan, Chen, Hedan, Xie, Ying, Zhou, Xue, Wang, Yun, Zhou, Jing, Long, Shiqi, Hu, Zuquan, Zhang, Shichao, Qiu, Wei, Zeng, Zhu, Liu, Lina · 2021 · Translational Oncology · DOI

Full title: Combination of CTLA-4 blockade with MUC1 mRNA nanovaccine induces enhanced anti-tumor CTL activity by modulating tumor microenvironment of triple negative breast cancer

Authors: Lin, Xuan, Chen, Hedan, Xie, Ying, Zhou, Xue, Wang, Yun, Zhou, Jing, Long, Shiqi, Hu, Zuquan, Zhang, Shichao, Qiu, Wei, Zeng, Zhu, Liu, Lina

Year: 2021

Venue: Translational Oncology

DOI: https://doi.org/10.1016/j.tranon.2021.101298

Paper Double Immune Checkpoint Blockade in Renal Cell Carcinoma

M. Luyo, L. Carril-Ajuria, F. Schutz, D. Castellano, G. Velasco · 2019 · Kidney Cancer · DOI

Full title: Double Immune Checkpoint Blockade in Renal Cell Carcinoma

Authors: M. Luyo, L. Carril-Ajuria, F. Schutz, D. Castellano, G. Velasco

Year: 2019

Venue: Kidney Cancer

DOI: https://doi.org/10.3233/kca-190054

Paper Immune checkpoint inhibitors-induced systemic capillary leak syndrome: A report of two cases.

Petitdemange, A, Béguin, L, Dimitrov, Y · 2023 · La Revue de medecine interne · DOI

Full title: Immune checkpoint inhibitors-induced systemic capillary leak syndrome: A report of two cases.

Authors: Petitdemange, A, Béguin, L, Dimitrov, Y

Year: 2023

Venue: La Revue de medecine interne

DOI: https://doi.org/10.1016/j.revmed.2022.11.001

Paper [Side effects of Modern Immunotherapy and How to Solve Them in the Clinics].

Lakomý, R, Poprach, A · 2015 · Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

Full title: [Side effects of Modern Immunotherapy and How to Solve Them in the Clinics].

Authors: Lakomý, R, Poprach, A

Year: 2015

Venue: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

Paper Acute renal failure in patient with renal cell carcinoma after combination immune checkpoint inhibitor therapy

Zang, Peter D., Lee, Ramon O., Smith, J. A. · 2021 · Current Problems in Cancer Case Reports · DOI

Full title: Acute renal failure in patient with renal cell carcinoma after combination immune checkpoint inhibitor therapy

Authors: Zang, Peter D., Lee, Ramon O., Smith, J. A.

Year: 2021

Venue: Current Problems in Cancer Case Reports

DOI: https://doi.org/10.1016/j.cpccr.2021.100082

Paper Abstract 4393: Tumor volumetric analysis to correlate disease burden with response to dual immune checkpoint blockade in metastatic NSCLC

Aminu, Muhammad, Vokes, Natalie I., Saad, Maliazurina B., Li, Hui, Hong, Lingzhi, Mohamed, Mohamed S., Boom, John, Chen, Pingjun, Altan, Mehmet, Gandhi, Saumil, Swisher, Stephen G., Antonoff, Mara B., Pozadzides, J.V., Blumenschein, George R., Gibbons, Don L., Cascone, Tina, Elamin, Yasir Y., Le, Xiuning, Negrão, Marcelo V., Skoulidis, Ferdinandos, Tsao, Anne S., Tu, Janet, Lee, J. Jack, Zhang, Jianjun, Heymach, John V., Wu, Jia · 2023 · Cancer Research · DOI

Full title: Abstract 4393: Tumor volumetric analysis to correlate disease burden with response to dual immune checkpoint blockade in metastatic NSCLC

Authors: Aminu, Muhammad, Vokes, Natalie I., Saad, Maliazurina B., Li, Hui, Hong, Lingzhi, Mohamed, Mohamed S., Boom, John, Chen, Pingjun, Altan, Mehmet, Gandhi, Saumil, Swisher, Stephen G., Antonoff, Mara B., Pozadzides, J.V., Blumenschein, George R., Gibbons, Don L., Cascone, Tina, Elamin, Yasir Y., Le, Xiuning, Negrão, Marcelo V., Skoulidis, Ferdinandos, Tsao, Anne S., Tu, Janet, Lee, J. Jack, Zhang, Jianjun, Heymach, John V., Wu, Jia

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-4393

Paper Abstract 2257: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (Durva) plus tremelimumab (T) following palliative hypofractionated radiotherapy (SBRT) in patients (pts) with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) progressing on chemotherapy: NSABP FC-9

Lee, James J., Yothers, Greg, George, Thomas J., Fakih, Marwan, Mallick, Atrayee Basu, Mitchell, Edith P., Wade, James L., Krauss, John C., Kayaleh, Omar, Heron, Dwight E., Allegra, Carmen J., Lipchik, Corey, Feng, Huichen, Joy, Marion, Srinivasan, Ashok, Pogue–Geile, Katherine L., Lucas, Peter C., Warren, Sarah, Cesano, Alessandra, Jacobs, Samuel A. · 2019 · Cancer Research · DOI

Full title: Abstract 2257: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (Durva) plus tremelimumab (T) following palliative hypofractionated radiotherapy (SBRT) in patients (pts) with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) progressing on chemotherapy: NSABP FC-9

Authors: Lee, James J., Yothers, Greg, George, Thomas J., Fakih, Marwan, Mallick, Atrayee Basu, Mitchell, Edith P., Wade, James L., Krauss, John C., Kayaleh, Omar, Heron, Dwight E., Allegra, Carmen J., Lipchik, Corey, Feng, Huichen, Joy, Marion, Srinivasan, Ashok, Pogue–Geile, Katherine L., Lucas, Peter C., Warren, Sarah, Cesano, Alessandra, Jacobs, Samuel A.

Year: 2019

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2019-2257

Paper Abstract 6464: Spatial mapping of the tumor microenvironment for combination therapy design

Arindam Bose, Susan Keezer, E. Alonzo, Sophie Struble, Jeremy Fisher, M. Norton, Richard A. Heil-Chapdelaine, N. F. Diaz Granados, V. Agrawal · 2025 · Cancer Research · DOI

Full title: Abstract 6464: Spatial mapping of the tumor microenvironment for combination therapy design

Authors: Arindam Bose, Susan Keezer, E. Alonzo, Sophie Struble, Jeremy Fisher, M. Norton, Richard A. Heil-Chapdelaine, N. F. Diaz Granados, V. Agrawal

Year: 2025

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2025-6464

Paper Toxicity of Checkpoint Inhibition in Advanced RCC: A Systematic Review.

Ornstein, Moshe C, Garcia, Jorge A · 2017 · Kidney cancer (Clifton, Va.) · DOI

Full title: Toxicity of Checkpoint Inhibition in Advanced RCC: A Systematic Review.

Authors: Ornstein, Moshe C, Garcia, Jorge A

Year: 2017

Venue: Kidney cancer (Clifton, Va.)

DOI: https://doi.org/10.3233/KCA-170017

Paper The Efficacy of Immune Checkpoint Inhibitors in Microsatellite Stable Colorectal Cancer: A Systematic Review

Güven, Deniz Can, Kavgacı, Gözde, Erul, Enes, Syed, Masood Pasha, Magge, Tara, Saeed, Anwaar, Yalçın, Şuayib, Şahin, İbrahim Halil · 2024 · The Oncologist · DOI

Full title: The Efficacy of Immune Checkpoint Inhibitors in Microsatellite Stable Colorectal Cancer: A Systematic Review

Authors: Güven, Deniz Can, Kavgacı, Gözde, Erul, Enes, Syed, Masood Pasha, Magge, Tara, Saeed, Anwaar, Yalçın, Şuayib, Şahin, İbrahim Halil

Year: 2024

Venue: The Oncologist

DOI: https://doi.org/10.1093/oncolo/oyae013

Paper Site‐specific response patterns, pseudoprogression, and acquired resistance in patients with melanoma treated with ipilimumab combined with anti–PD‐1 therapy

Silva, Inês Pires da, Lo, Serigne, Quek, Camelia, Gonzalez, Maria, Carlino, Matteo S., Long, Georgina V., Menzies, Alexander M. · 2019 · Cancer · DOI

Full title: Site‐specific response patterns, pseudoprogression, and acquired resistance in patients with melanoma treated with ipilimumab combined with anti–PD‐1 therapy

Authors: Silva, Inês Pires da, Lo, Serigne, Quek, Camelia, Gonzalez, Maria, Carlino, Matteo S., Long, Georgina V., Menzies, Alexander M.

Year: 2019

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.32522

Paper Indoleamine-2,3-Dioxygenase in Non–Small Cell Lung Cancer: A Targetable Mechanism of Immune Resistance Frequently Coexpressed With PD-L1

Ashley K. Volaric, R. Gentzler, R. Hall, J. H. Mehaffey, E. Stelow, T. Bullock, L. Martin, A. Mills · 2018 · American Journal of Surgical Pathology · DOI

Full title: Indoleamine-2,3-Dioxygenase in Non–Small Cell Lung Cancer: A Targetable Mechanism of Immune Resistance Frequently Coexpressed With PD-L1

Authors: Ashley K. Volaric, R. Gentzler, R. Hall, J. H. Mehaffey, E. Stelow, T. Bullock, L. Martin, A. Mills

Year: 2018

Venue: American Journal of Surgical Pathology

DOI: https://doi.org/10.1097/pas.0000000000001099

Paper Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy.

Siwicki, Marie, Gort-Freitas, Nicolas A, Messemaker, Marius, Bill, Ruben, Gungabeesoon, Jeremy, Engblom, Camilla, Zilionis, Rapolas, Garris, Christopher, Gerhard, Genevieve M, Kohl, Anna, Lin, Yunkang, Zou, Angela E, Cianciaruso, Chiara, Bolli, Evangelia, Pfirschke, Christina, Lin, Yi-Jang, Piot, Cecile, Mindur, John E, Talele, Nilesh, Kohler, Rainer H, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Pai, Sara I, deVito, Claudio, Koessler, Thibaud, Merkler, Doron, Coukos, Alexander, Wicky, Alexandre, Fraga, Montserrat, Sempoux, Christine, Jain, Rakesh K, Dietrich, Pierre-Yves, Michielin, Olivier, Weissleder, Ralph, Klein, Allon M, Pittet, Mikael J · 2021 · Science immunology · DOI

Full title: Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy.

Authors: Siwicki, Marie, Gort-Freitas, Nicolas A, Messemaker, Marius, Bill, Ruben, Gungabeesoon, Jeremy, Engblom, Camilla, Zilionis, Rapolas, Garris, Christopher, Gerhard, Genevieve M, Kohl, Anna, Lin, Yunkang, Zou, Angela E, Cianciaruso, Chiara, Bolli, Evangelia, Pfirschke, Christina, Lin, Yi-Jang, Piot, Cecile, Mindur, John E, Talele, Nilesh, Kohler, Rainer H, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Pai, Sara I, deVito, Claudio, Koessler, Thibaud, Merkler, Doron, Coukos, Alexander, Wicky, Alexandre, Fraga, Montserrat, Sempoux, Christine, Jain, Rakesh K, Dietrich, Pierre-Yves, Michielin, Olivier, Weissleder, Ralph, Klein, Allon M, Pittet, Mikael J

Year: 2021

Venue: Science immunology

DOI: https://doi.org/10.1126/sciimmunol.abi7083

Paper Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

Elsas, Andrea van, Hurwitz, Arthur A., Allison, James P. · 1999 · The Journal of Experimental Medicine · DOI

Full title: Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

Authors: Elsas, Andrea van, Hurwitz, Arthur A., Allison, James P.

Year: 1999

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.190.3.355

Paper [What is the place of the combinations for immunotherapy with chemotherapy or with other immune checkpoint inhibitors?].

Douchet, Gaëlle, Aspeslagh, Sandrine · 2017 · Bulletin du cancer · DOI

Full title: [What is the place of the combinations for immunotherapy with chemotherapy or with other immune checkpoint inhibitors?].

Authors: Douchet, Gaëlle, Aspeslagh, Sandrine

Year: 2017

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2017.03.008

Paper Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.

Adam, Lucas C, Raja, Junaid, Ludwig, Johannes M, Adeniran, Adebowale, Gettinger, Scott N, Kim, Hyun S · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.

Authors: Adam, Lucas C, Raja, Junaid, Ludwig, Johannes M, Adeniran, Adebowale, Gettinger, Scott N, Kim, Hyun S

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0468-x

Paper Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.

Sinha, Meenal, Zhang, Li, Subudhi, Sumit, Chen, Brandon, Marquez, Jaqueline, Liu, Eric V, Allaire, Kate, Cheung, Alexander, Ng, Sharon, Nguyen, Christopher, Friedlander, Terence W, Aggarwal, Rahul, Spitzer, Matthew, Allison, James P, Small, Eric J, Sharma, Padmanee, Fong, Lawrence · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.

Authors: Sinha, Meenal, Zhang, Li, Subudhi, Sumit, Chen, Brandon, Marquez, Jaqueline, Liu, Eric V, Allaire, Kate, Cheung, Alexander, Ng, Sharon, Nguyen, Christopher, Friedlander, Terence W, Aggarwal, Rahul, Spitzer, Matthew, Allison, James P, Small, Eric J, Sharma, Padmanee, Fong, Lawrence

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-002254

Paper Identification of anti-TIM-3 based checkpoint inhibitor combinations with activity in immunotherapy refractory melanoma models.

Phadke, Manali S, Li, Jiannong, Sriramareddy, Sathya, Rodriguez, Paulo C, Ruffell, Brian, Luca, Vincent C, Tran, Thuy T T, Chen, Yian Ann, Smalley, Keiran S M · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Identification of anti-TIM-3 based checkpoint inhibitor combinations with activity in immunotherapy refractory melanoma models.

Authors: Phadke, Manali S, Li, Jiannong, Sriramareddy, Sathya, Rodriguez, Paulo C, Ruffell, Brian, Luca, Vincent C, Tran, Thuy T T, Chen, Yian Ann, Smalley, Keiran S M

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2025-012011

Paper Bringing immunotherapy to clinical practice in dMMR/MSI-high colon cancer.

Randon, Giovanni, Montroni, Isacco, Pietrantonio, Filippo · 2025 · Cancer cell · DOI

Full title: Bringing immunotherapy to clinical practice in dMMR/MSI-high colon cancer.

Authors: Randon, Giovanni, Montroni, Isacco, Pietrantonio, Filippo

Year: 2025

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2025.08.010

Paper Research advances in immune checkpoint drugs for non-small cell lung cancer.

Shen, Yue, Chen, Juan, Li, Xiang-Ping · 2023 · Journal of drug targeting · DOI

Full title: Research advances in immune checkpoint drugs for non-small cell lung cancer.

Authors: Shen, Yue, Chen, Juan, Li, Xiang-Ping

Year: 2023

Venue: Journal of drug targeting

DOI: https://doi.org/10.1080/1061186X.2023.2235098

Paper Combination Immunotherapy: An Emerging Paradigm in Cancer Therapeutics.

Wang, Daniel Y, Sosman, Jeffrey A, Johnson, Douglas B · 2015 · Oncology (Williston Park, N.Y.)

Full title: Combination Immunotherapy: An Emerging Paradigm in Cancer Therapeutics.

Authors: Wang, Daniel Y, Sosman, Jeffrey A, Johnson, Douglas B

Year: 2015

Venue: Oncology (Williston Park, N.Y.)

Paper Development of a Clinically Oriented Model to Predict Antitumor Effects after PD-1/PD-L1 Inhibitor Therapy

Xueping Wang, Zhonglian He, Wen Liu, Runkun Han, Huilan Li, Shuqin Dai, Lin Zhang, M. Mao · 2022 · Journal of Oncology · DOI

Full title: Development of a Clinically Oriented Model to Predict Antitumor Effects after PD-1/PD-L1 Inhibitor Therapy

Authors: Xueping Wang, Zhonglian He, Wen Liu, Runkun Han, Huilan Li, Shuqin Dai, Lin Zhang, M. Mao

Year: 2022

Venue: Journal of Oncology

DOI: https://doi.org/10.1155/2022/9030782

Paper Mechanistic considerations in chemotherapeutic activity of caffeine.

Tej, Gullanki Naga Venkata Charan, Nayak, Prasanta Kumar · 2018 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Mechanistic considerations in chemotherapeutic activity of caffeine.

Authors: Tej, Gullanki Naga Venkata Charan, Nayak, Prasanta Kumar

Year: 2018

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2018.05.144

Paper A comprehensive review of immune checkpoint inhibitors for cancer treatment.

Arafat Hossain, Md · 2024 · International immunopharmacology · DOI

Full title: A comprehensive review of immune checkpoint inhibitors for cancer treatment.

Authors: Arafat Hossain, Md

Year: 2024

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2024.113365

Paper The multifaceted nature of diabetes mellitus induced by checkpoint inhibitors.

Marchand, Lucien, Disse, Emmanuel, Dalle, Stéphane, Reffet, Sophie, Vouillarmet, Julien, Fabien, Nicole, Thivolet, Charles, Cugnet-Anceau, Christine · 2019 · Acta diabetologica · DOI

Full title: The multifaceted nature of diabetes mellitus induced by checkpoint inhibitors.

Authors: Marchand, Lucien, Disse, Emmanuel, Dalle, Stéphane, Reffet, Sophie, Vouillarmet, Julien, Fabien, Nicole, Thivolet, Charles, Cugnet-Anceau, Christine

Year: 2019

Venue: Acta diabetologica

DOI: https://doi.org/10.1007/s00592-019-01402-w

Paper Programmable Porous Silicon Microparticles for Temporally Staged Drug Delivery in Combination Cancer Immunotherapy.

Jeong, Moonkyoung, Yoon, Junyong, Kim, Kyunghwan, Wang, Joanna, Koo, Yonghoe, Sailor, Michael J, Joo, Jinmyoung, Park, Ji-Ho · 2025 · ACS applied materials & interfaces · DOI

Full title: Programmable Porous Silicon Microparticles for Temporally Staged Drug Delivery in Combination Cancer Immunotherapy.

Authors: Jeong, Moonkyoung, Yoon, Junyong, Kim, Kyunghwan, Wang, Joanna, Koo, Yonghoe, Sailor, Michael J, Joo, Jinmyoung, Park, Ji-Ho

Year: 2025

Venue: ACS applied materials & interfaces

DOI: https://doi.org/10.1021/acsami.4c19425

Paper The Role of Immunotherapy in Extensive Stage Small-Cell Lung Cancer: A Review of the Literature.

Tsiouprou, Ioanna, Zaharias, Athanasios, Spyratos, Dionisios · 2019 · Canadian respiratory journal · DOI

Full title: The Role of Immunotherapy in Extensive Stage Small-Cell Lung Cancer: A Review of the Literature.

Authors: Tsiouprou, Ioanna, Zaharias, Athanasios, Spyratos, Dionisios

Year: 2019

Venue: Canadian respiratory journal

DOI: https://doi.org/10.1155/2019/6860432

Paper Abstract A098: Single nuclear profiling reveals type I IFN-mediated immune remodeling in platinum-refractory HRD-mutant PDAC responsive to checkpoint immunotherapy

Shersher, Elena, Nivelo, Luis, Oh, Cindy, Ogobuiro, Ifeanyichukwu C., Caeiro, Lucas D., Amirian, Haleh, Rajkumar, Karthik, Adams, Andrew M., Sharma, Piyush Kumar, Merchant, Nipun B., Borazanci, Erkut, Legrand, S. Danielle., Verdún, Ramiro E., Bianchi, Anna, Hosein, Peter J., Datta, Jashodeep · 2025 · Cancer Research · DOI

Full title: Abstract A098: Single nuclear profiling reveals type I IFN-mediated immune remodeling in platinum-refractory HRD-mutant PDAC responsive to checkpoint immunotherapy

Authors: Shersher, Elena, Nivelo, Luis, Oh, Cindy, Ogobuiro, Ifeanyichukwu C., Caeiro, Lucas D., Amirian, Haleh, Rajkumar, Karthik, Adams, Andrew M., Sharma, Piyush Kumar, Merchant, Nipun B., Borazanci, Erkut, Legrand, S. Danielle., Verdún, Ramiro E., Bianchi, Anna, Hosein, Peter J., Datta, Jashodeep

Year: 2025

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.pancreatic25-a098

Paper Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review.

Wanchoo, Rimda, Karam, Sabine, Uppal, Nupur N, Barta, Valerie S, Deray, Gilbert, Devoe, Craig, Launay-Vacher, Vincent, Jhaveri, Kenar D, Cancer and Kidney International Network Workgroup on Immune Checkpoint Inhibitors · 2017 · American journal of nephrology · DOI

Full title: Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review.

Authors: Wanchoo, Rimda, Karam, Sabine, Uppal, Nupur N, Barta, Valerie S, Deray, Gilbert, Devoe, Craig, Launay-Vacher, Vincent, Jhaveri, Kenar D, Cancer and Kidney International Network Workgroup on Immune Checkpoint Inhibitors

Year: 2017

Venue: American journal of nephrology

DOI: https://doi.org/10.1159/000455014

Paper Combined Immune Checkpoint Blockade.

Drake, Charles G · 2015 · Seminars in oncology · DOI

Full title: Combined Immune Checkpoint Blockade.

Authors: Drake, Charles G

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.05.002

Paper Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors.

de Malet, Alice, Antoni, Guillemette, Collins, Michael, Soularue, Emilie, Marthey, Lysiane, Vaysse, Thibaut, Coutzac, Clelia, Chaput, Nathalie, Mateus, Christine, Robert, Caroline, Carbonnel, Franck · 2019 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors.

Authors: de Malet, Alice, Antoni, Guillemette, Collins, Michael, Soularue, Emilie, Marthey, Lysiane, Vaysse, Thibaut, Coutzac, Clelia, Chaput, Nathalie, Mateus, Christine, Robert, Caroline, Carbonnel, Franck

Year: 2019

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2018.10.006

Paper Novel immunotherapy in the treatment of advanced non-small cell lung cancer.

Santabarbara, G, Maione, P, Rossi, A, Palazzolo, G, Gridelli, C · 2016 · Expert review of clinical pharmacology · DOI

Full title: Novel immunotherapy in the treatment of advanced non-small cell lung cancer.

Authors: Santabarbara, G, Maione, P, Rossi, A, Palazzolo, G, Gridelli, C

Year: 2016

Venue: Expert review of clinical pharmacology

DOI: https://doi.org/10.1080/17512433.2016.1236681

Paper Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Ju, Mingyi, Zhang, Jiaojiao, Deng, Zhuoyuan, Wei, Minjie, Ma, Lianghua, Chen, Ting, Zhao, Lin · 2024 · Journal for immunotherapy of cancer · DOI

Full title: Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Authors: Ju, Mingyi, Zhang, Jiaojiao, Deng, Zhuoyuan, Wei, Minjie, Ma, Lianghua, Chen, Ting, Zhao, Lin

Year: 2024

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-009345

Paper Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies.

Philips, George K, Atkins, Michael · 2015 · International immunology · DOI

Full title: Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies.

Authors: Philips, George K, Atkins, Michael

Year: 2015

Venue: International immunology

DOI: https://doi.org/10.1093/intimm/dxu095

Paper Nephrotoxicity of immune checkpoint inhibitor combination therapy in patients with advanced renal cell carcinoma: a meta-analysis.

Tan, An-Ju, Mo, Dun-Chang, Wu, Ka, Pan, Hong-Mei, Wang, Dong-Mei, Xu, Xing-Xin, Chen, Min-Hong, Pan, Shu-Ying, Li, Rou, Lian, Wen-Jiao, Wei, Meng-Han · 2023 · World journal of urology · DOI

Full title: Nephrotoxicity of immune checkpoint inhibitor combination therapy in patients with advanced renal cell carcinoma: a meta-analysis.

Authors: Tan, An-Ju, Mo, Dun-Chang, Wu, Ka, Pan, Hong-Mei, Wang, Dong-Mei, Xu, Xing-Xin, Chen, Min-Hong, Pan, Shu-Ying, Li, Rou, Lian, Wen-Jiao, Wei, Meng-Han

Year: 2023

Venue: World journal of urology

DOI: https://doi.org/10.1007/s00345-023-04407-x

Paper Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments.

Muraro, Manuele G, Muenst, Simone, Mele, Valentina, Quagliata, Luca, Iezzi, Giandomenica, Tzankov, Alexandar, Weber, Walter P, Spagnoli, Giulio C, Soysal, Savas D · 2017 · Oncoimmunology · DOI

Full title: Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments.

Authors: Muraro, Manuele G, Muenst, Simone, Mele, Valentina, Quagliata, Luca, Iezzi, Giandomenica, Tzankov, Alexandar, Weber, Walter P, Spagnoli, Giulio C, Soysal, Savas D

Year: 2017

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2017.1331798

Paper Lymphocyte-activation gene 3 (LAG-3) as a promising immune checkpoint in cancer immunotherapy: From biology to the clinic.

Alqurashi, Yaser E · 2024 · Pathology, research and practice · DOI

Full title: Lymphocyte-activation gene 3 (LAG-3) as a promising immune checkpoint in cancer immunotherapy: From biology to the clinic.

Authors: Alqurashi, Yaser E

Year: 2024

Venue: Pathology, research and practice

DOI: https://doi.org/10.1016/j.prp.2024.155124

Paper Cutaneous adverse effects of the immune checkpoint inhibitors.

Collins, Lindsey K, Chapman, M Shane, Carter, Joi B, Samie, Faramarz H · 2017 · Current problems in cancer · DOI

Full title: Cutaneous adverse effects of the immune checkpoint inhibitors.

Authors: Collins, Lindsey K, Chapman, M Shane, Carter, Joi B, Samie, Faramarz H

Year: 2017

Venue: Current problems in cancer

DOI: https://doi.org/10.1016/j.currproblcancer.2016.12.001

Paper Low-dose Radiation Improves Tumor Immune Microenvironment, Enhancing the Effects of Anti-CTLA-4 Therapy.

Dong, Jigang, Qi, Ying, Sha, Sha · 2025 · Iranian journal of immunology : IJI · DOI

Full title: Low-dose Radiation Improves Tumor Immune Microenvironment, Enhancing the Effects of Anti-CTLA-4 Therapy.

Authors: Dong, Jigang, Qi, Ying, Sha, Sha

Year: 2025

Venue: Iranian journal of immunology : IJI

DOI: https://doi.org/10.22034/iji.2025.103258.2825

Paper Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer

Laumont, Céline M., Wouters, Maartje C.A., Smazynski, Julian, Gierc, Nicole S., Chavez, Elizabeth A., Chong, Lauren C., Thornton, Shelby, Milne, Katy, Webb, John R., Steidl, Christian, Nelson, Brad H. · 2021 · Clinical Cancer Research · DOI

Full title: Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer

Authors: Laumont, Céline M., Wouters, Maartje C.A., Smazynski, Julian, Gierc, Nicole S., Chavez, Elizabeth A., Chong, Lauren C., Thornton, Shelby, Milne, Katy, Webb, John R., Steidl, Christian, Nelson, Brad H.

Year: 2021

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-20-4394

Paper Cross-Disease myeloid remodeling along the GMP-TAM axis predicts immunotherapy response in glioma.

Zhang, Yuanyuan, Liu, Xin, Hua, Shi · 2026 · Brain research · DOI

Full title: Cross-Disease myeloid remodeling along the GMP-TAM axis predicts immunotherapy response in glioma.

Authors: Zhang, Yuanyuan, Liu, Xin, Hua, Shi

Year: 2026

Venue: Brain research

DOI: https://doi.org/10.1016/j.brainres.2025.150083

Paper DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/elife.87292.3

Paper The clinical value of combination of immune checkpoint inhibitors in cancer patients: A meta-analysis of efficacy and safety.

Wu, Yingcheng, Shi, Hui, Jiang, Maorong, Qiu, Mingyan, Jia, Keren, Cao, Tianyue, Shang, Yujuan, Shi, Lili, Jiang, Kui, Wu, Huiqun · 2017 · International journal of cancer · DOI

Full title: The clinical value of combination of immune checkpoint inhibitors in cancer patients: A meta-analysis of efficacy and safety.

Authors: Wu, Yingcheng, Shi, Hui, Jiang, Maorong, Qiu, Mingyan, Jia, Keren, Cao, Tianyue, Shang, Yujuan, Shi, Lili, Jiang, Kui, Wu, Huiqun

Year: 2017

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.31012

Paper A meta-analysis of the efficacy of programmed cell death 1/its ligand inhibitors plus cytotoxic T-lymphocyte-associated antigen 4 inhibitors in non-small cell lung cancer.

Lin, Li, Xiao, Lu, Li, Lei, Chen, Chen, Zhang, Haorong, Yu, Changyan, Zhang, Lanfang, Wei, Anhua, Li, Wei · 2024 · Frontiers in pharmacology · DOI

Full title: A meta-analysis of the efficacy of programmed cell death 1/its ligand inhibitors plus cytotoxic T-lymphocyte-associated antigen 4 inhibitors in non-small cell lung cancer.

Authors: Lin, Li, Xiao, Lu, Li, Lei, Chen, Chen, Zhang, Haorong, Yu, Changyan, Zhang, Lanfang, Wei, Anhua, Li, Wei

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1267763

Paper Longitudinal plasma proteomic analysis: A monitoring strategy for NSCLC patients treated with immunotherapy.

Y. Elon, Yehuda Brody, G. Lowenthal, E. Jacob, Or Itzhaki, I. Sela, Shani Raveh, A. Gowan, Maria I. Juarez-Perez, H. Singh, Sachin Agarwal, Rakesh Surapaneni, B. Nair, A. Dicker, Y. Chae, V. Anagnostou, R. Kelly · 2025 · Journal of Clinical Oncology · DOI

Full title: Longitudinal plasma proteomic analysis: A monitoring strategy for NSCLC patients treated with immunotherapy.

Authors: Y. Elon, Yehuda Brody, G. Lowenthal, E. Jacob, Or Itzhaki, I. Sela, Shani Raveh, A. Gowan, Maria I. Juarez-Perez, H. Singh, Sachin Agarwal, Rakesh Surapaneni, B. Nair, A. Dicker, Y. Chae, V. Anagnostou, R. Kelly

Year: 2025

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2025.43.16_suppl.8579

Paper Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells.

Rashidian, Mohammad, Ingram, Jessica R, Dougan, Michael, Dongre, Anushka, Whang, Katherine A, LeGall, Camille, Cragnolini, Juan J, Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M, Bhan, Atul, Weinberg, Robert A, Ploegh, Hidde L · 2017 · The Journal of experimental medicine · DOI

Full title: Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells.

Authors: Rashidian, Mohammad, Ingram, Jessica R, Dougan, Michael, Dongre, Anushka, Whang, Katherine A, LeGall, Camille, Cragnolini, Juan J, Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M, Bhan, Atul, Weinberg, Robert A, Ploegh, Hidde L

Year: 2017

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20161950

Paper Use of HSP90 inhibitors in the combination immunotherapy of melanoma (P4272)

Subhara Raveendran, A. Rao, W. Storkus · 2013 · Journal of Immunology · DOI

Full title: Use of HSP90 inhibitors in the combination immunotherapy of melanoma (P4272)

Authors: Subhara Raveendran, A. Rao, W. Storkus

Year: 2013

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.190.supp.140.8

Paper In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments.

Morris, Zachary S, Guy, Emily I, Francis, David M, Gressett, Monica M, Werner, Lauryn R, Carmichael, Lakeesha L, Yang, Richard K, Armstrong, Eric A, Huang, Shyhmin, Navid, Fariba, Gillies, Stephen D, Korman, Alan, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M · 2016 · Cancer research · DOI

Full title: In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments.

Authors: Morris, Zachary S, Guy, Emily I, Francis, David M, Gressett, Monica M, Werner, Lauryn R, Carmichael, Lakeesha L, Yang, Richard K, Armstrong, Eric A, Huang, Shyhmin, Navid, Fariba, Gillies, Stephen D, Korman, Alan, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M

Year: 2016

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2644

Paper Combination with Stereotactic Body Radiotherapy Offers a Promising Strategy to Overcome Resistance to Immunotherapy in Advanced Renal Cell Cancer.

Sun, Xiaowen, Gan, Lu, Na, Aru, Ge, Lingling, Chen, Baoqing, Liu, Jiaming · 2019 · Journal of oncology · DOI

Full title: Combination with Stereotactic Body Radiotherapy Offers a Promising Strategy to Overcome Resistance to Immunotherapy in Advanced Renal Cell Cancer.

Authors: Sun, Xiaowen, Gan, Lu, Na, Aru, Ge, Lingling, Chen, Baoqing, Liu, Jiaming

Year: 2019

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2019/1483406

Paper Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model.

Hartmann, Laura, Osen, Wolfram, Eichmüller, Oliver L, Kordaß, Theresa, Furkel, Jennifer, Dickes, Elke, Reid, Carissa, Debus, Jürgen, Brons, Stephan, Abdollahi, Amir, Moustafa, Mahmoud, Rieken, Stefan, Eichmüller, Stefan B · 2022 · Cancer letters · DOI

Full title: Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model.

Authors: Hartmann, Laura, Osen, Wolfram, Eichmüller, Oliver L, Kordaß, Theresa, Furkel, Jennifer, Dickes, Elke, Reid, Carissa, Debus, Jürgen, Brons, Stephan, Abdollahi, Amir, Moustafa, Mahmoud, Rieken, Stefan, Eichmüller, Stefan B

Year: 2022

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2022.215928

Paper Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients.

Subrahmanyam, Priyanka B, Dong, Zhiwan, Gusenleitner, Daniel, Giobbie-Hurder, Anita, Severgnini, Mariano, Zhou, Jun, Manos, Michael, Eastman, Lauren M, Maecker, Holden T, Hodi, F Stephen · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients.

Authors: Subrahmanyam, Priyanka B, Dong, Zhiwan, Gusenleitner, Daniel, Giobbie-Hurder, Anita, Severgnini, Mariano, Zhou, Jun, Manos, Michael, Eastman, Lauren M, Maecker, Holden T, Hodi, F Stephen

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0328-8

Paper Breast Cancer Immunotherapy: A Team Science Approach.

Duesberg, Max, LeVee, Alexis, Chang, Hannah, Tsai, Karen, Crossman, Bridget, Tadi, Marissa, Xu, Sharon, Wheeler, Deric, Kang, Irene · 2025 · Cancer treatment and research · DOI

Full title: Breast Cancer Immunotherapy: A Team Science Approach.

Authors: Duesberg, Max, LeVee, Alexis, Chang, Hannah, Tsai, Karen, Crossman, Bridget, Tadi, Marissa, Xu, Sharon, Wheeler, Deric, Kang, Irene

Year: 2025

Venue: Cancer treatment and research

DOI: https://doi.org/10.1007/978-3-031-97242-3_4

Paper TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.

Sharma, Naveen, Vacher, Jean, Allison, James P · 2019 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.

Authors: Sharma, Naveen, Vacher, Jean, Allison, James P

Year: 2019

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1819004116

Paper Optimal radiation dose to induce an abscopal effect by combining carbon-ion radiotherapy and anti-CTLA4 antibody.

Ma, Liqiu, Li, Yang, Sakamoto, Yoshimitsu, Xie, Lin, Suzuki, Saaya, Yoshida, Yukari, Sui, Li, Guo, Gang, Wen, Jialing, Ren, Wangcai, Kakimi, Kazuhiro, Osada, Kensuke, Takahashi, Akihisa, Shimokawa, Takashi · 2025 · Neoplasia (New York, N.Y.) · DOI

Full title: Optimal radiation dose to induce an abscopal effect by combining carbon-ion radiotherapy and anti-CTLA4 antibody.

Authors: Ma, Liqiu, Li, Yang, Sakamoto, Yoshimitsu, Xie, Lin, Suzuki, Saaya, Yoshida, Yukari, Sui, Li, Guo, Gang, Wen, Jialing, Ren, Wangcai, Kakimi, Kazuhiro, Osada, Kensuke, Takahashi, Akihisa, Shimokawa, Takashi

Year: 2025

Venue: Neoplasia (New York, N.Y.)

DOI: https://doi.org/10.1016/j.neo.2024.101099

Paper Current status of immunotherapy in gastrointestinal malignancies.

Lorenzen, Sylvie, Lordick, Florian, Loosen, Sven Heiko, Tacke, Frank, Trautwein, Christian, Roderburg, Christoph, Ettrich, Thomas J, Perkhofer, Lukas, Reinacher-Schick, Anke, Stein, Alexander · 2020 · Zeitschrift fur Gastroenterologie · DOI

Full title: Current status of immunotherapy in gastrointestinal malignancies.

Authors: Lorenzen, Sylvie, Lordick, Florian, Loosen, Sven Heiko, Tacke, Frank, Trautwein, Christian, Roderburg, Christoph, Ettrich, Thomas J, Perkhofer, Lukas, Reinacher-Schick, Anke, Stein, Alexander

Year: 2020

Venue: Zeitschrift fur Gastroenterologie

DOI: https://doi.org/10.1055/a-1071-8322

Paper Neoadjuvant immune checkpoint inhibitors in cancer, current state of the art.

Le Saux, Olivia, Lounici, Yasmine, Wajda, Pauline, Barrin, Sarah, Caux, Christophe, Dubois, Bertrand, Ray-Coquard, Isabelle · 2021 · Critical reviews in oncology/hematology · DOI

Full title: Neoadjuvant immune checkpoint inhibitors in cancer, current state of the art.

Authors: Le Saux, Olivia, Lounici, Yasmine, Wajda, Pauline, Barrin, Sarah, Caux, Christophe, Dubois, Bertrand, Ray-Coquard, Isabelle

Year: 2021

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2020.103172

Paper A Single-Arm Phase 2 Trial of Doxorubicin Plus Zalifrelimab (Anti-CTLA-4 Antibody) and Balstilimab (Anti-PD-1 Antibody) in Advanced/Metastatic Soft Tissue Sarcomas.

Wilky, Breelyn A, Julian, Katherine A, Maleddu, Alessandra, Mailhot, Anne C, Cartwright, Chelsey R, Gao, Dexiang, Moreno Tellez, Cristiam, Kemp, Lindsey E, Therrien, Nicholas R, Chaudhry, Sumra S, Rytlewski, Jeffrey D, Brockman, Qierra R, Davila, Eduardo, Elias, Anthony D · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: A Single-Arm Phase 2 Trial of Doxorubicin Plus Zalifrelimab (Anti-CTLA-4 Antibody) and Balstilimab (Anti-PD-1 Antibody) in Advanced/Metastatic Soft Tissue Sarcomas.

Authors: Wilky, Breelyn A, Julian, Katherine A, Maleddu, Alessandra, Mailhot, Anne C, Cartwright, Chelsey R, Gao, Dexiang, Moreno Tellez, Cristiam, Kemp, Lindsey E, Therrien, Nicholas R, Chaudhry, Sumra S, Rytlewski, Jeffrey D, Brockman, Qierra R, Davila, Eduardo, Elias, Anthony D

Year: 2025

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-25-0618

Paper Combination immunotherapy with IDO vaccine and PD-1 inhibitors in advanced NSCLC.

Mellemgaard, Anders, engel-Norregaard, Lotte, Andersen, Mads Hald, Zocca, Mai-Britt, Svane, Inge Marie · 2017 · Journal of Clinical Oncology · DOI

Full title: Combination immunotherapy with IDO vaccine and PD-1 inhibitors in advanced NSCLC.

Authors: Mellemgaard, Anders, engel-Norregaard, Lotte, Andersen, Mads Hald, Zocca, Mai-Britt, Svane, Inge Marie

Year: 2017

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2017.35.15_suppl.tps2610

Paper Coxsackievirus A21 Synergizes with Checkpoint Inhibitors.

· 2017 · Cancer discovery · DOI

Full title: Coxsackievirus A21 Synergizes with Checkpoint Inhibitors.

Year: 2017

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-NB2017-051

Paper Systemic therapies in hepatocellular carcinoma: A revolution?

Fortuny, Marta, Sanduzzi‐Zamparelli, Marco, Reig, María · 2024 · United European Gastroenterology Journal · DOI

Full title: Systemic therapies in hepatocellular carcinoma: A revolution?

Authors: Fortuny, Marta, Sanduzzi‐Zamparelli, Marco, Reig, María

Year: 2024

Venue: United European Gastroenterology Journal

DOI: https://doi.org/10.1002/ueg2.12510

Paper Immune-checkpoint inhibitors plus chemotherapy versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer.

Zhou, Fei, Zhao, Wencheng, Gong, Xiaomei, Ren, Shengxiang, Su, Chunxia, Jiang, Tao, Zhou, Caicun · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Immune-checkpoint inhibitors plus chemotherapy versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer.

Authors: Zhou, Fei, Zhao, Wencheng, Gong, Xiaomei, Ren, Shengxiang, Su, Chunxia, Jiang, Tao, Zhou, Caicun

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-001300

Paper Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: beyond traditional treatment approaches.

Spigel, David R, Socinski, Mark A · 2013 · Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · DOI

Full title: Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: beyond traditional treatment approaches.

Authors: Spigel, David R, Socinski, Mark A

Year: 2013

Venue: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

DOI: https://doi.org/10.1097/JTO.0b013e318286cf88

Paper Combined PD-1 and CTLA-4 Blockade Increases the Risks of Multiple Pituitary Hormone Deficiency and Isolated Adrenocorticotropic Deficiency: A Prospective Study.

Iwama, Shintaro, Kobayashi, Tomoko, Izuchi, Tetsushi, Suzuki, Koji, Murase, Takanori, Ando, Masahiko, Handa, Tomoko, Onoue, Takeshi, Miyata, Takashi, Sugiyama, Mariko, Hagiwara, Daisuke, Suga, Hidetaka, Banno, Ryoichi, Hase, Tetsunari, Mori, Shoichiro, Sano, Tomoyasu, Akamatsu, Shusuke, Akiyama, Masashi, Ishii, Makoto, Arima, Hiroshi · 2025 · Endocrinology and metabolism (Seoul, Korea) · DOI

Full title: Combined PD-1 and CTLA-4 Blockade Increases the Risks of Multiple Pituitary Hormone Deficiency and Isolated Adrenocorticotropic Deficiency: A Prospective Study.

Authors: Iwama, Shintaro, Kobayashi, Tomoko, Izuchi, Tetsushi, Suzuki, Koji, Murase, Takanori, Ando, Masahiko, Handa, Tomoko, Onoue, Takeshi, Miyata, Takashi, Sugiyama, Mariko, Hagiwara, Daisuke, Suga, Hidetaka, Banno, Ryoichi, Hase, Tetsunari, Mori, Shoichiro, Sano, Tomoyasu, Akamatsu, Shusuke, Akiyama, Masashi, Ishii, Makoto, Arima, Hiroshi

Year: 2025

Venue: Endocrinology and metabolism (Seoul, Korea)

DOI: https://doi.org/10.3803/EnM.2024.2180

Paper Enhanced CTLA-4 blockade anti-tumor immunity with APG-157 combination in a murine head and neck cancer.

Shin, Daniel Sanghoon, Basak, Saroj, Veena, Mysore S, Comin-Anduix, Begoña, Bhattacharya, Arjun, Dong, Tien S, Ko, Albert, Han, Philip, Jacobs, Jonathan, Moatamed, Neda A, Avila, Luis, Pellegrini, Matteo, Wang, Marilene, Srivatsan, Eri S · 2024 · Cancer medicine · DOI

Full title: Enhanced CTLA-4 blockade anti-tumor immunity with APG-157 combination in a murine head and neck cancer.

Authors: Shin, Daniel Sanghoon, Basak, Saroj, Veena, Mysore S, Comin-Anduix, Begoña, Bhattacharya, Arjun, Dong, Tien S, Ko, Albert, Han, Philip, Jacobs, Jonathan, Moatamed, Neda A, Avila, Luis, Pellegrini, Matteo, Wang, Marilene, Srivatsan, Eri S

Year: 2024

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.7212

Paper Development of shellfish allergy after exposure to dual immune checkpoint blockade.

Brown, Zachary J, Heinrich, Bernd, Greten, Tim F · 2018 · Hepatic oncology · DOI

Full title: Development of shellfish allergy after exposure to dual immune checkpoint blockade.

Authors: Brown, Zachary J, Heinrich, Bernd, Greten, Tim F

Year: 2018

Venue: Hepatic oncology

DOI: https://doi.org/10.2217/hep-2017-0021

Paper Combination Immunotherapy for Pancreatic Cancer Appears Promising in Johns Hopkins Platform Trial

Levin-Epstein, Michael · 2023 · Journal of Clinical Engineering · DOI

Full title: Combination Immunotherapy for Pancreatic Cancer Appears Promising in Johns Hopkins Platform Trial

Authors: Levin-Epstein, Michael

Year: 2023

Venue: Journal of Clinical Engineering

DOI: https://doi.org/10.1097/jce.0000000000000614

Paper Uncommon BRAF Mutations Associated with Durable Response to Immunotherapy in Patients with Metastatic Melanoma.

Swofford, Brenen P, Homsi, Jade · 2017 · Case reports in oncological medicine · DOI

Full title: Uncommon BRAF Mutations Associated with Durable Response to Immunotherapy in Patients with Metastatic Melanoma.

Authors: Swofford, Brenen P, Homsi, Jade

Year: 2017

Venue: Case reports in oncological medicine

DOI: https://doi.org/10.1155/2017/8241624

Paper PD-L1 antibody-modified plant-derived nanovesicles carrying a STING agonist for the combinational immunotherapy of melanoma

Xu, Zhanxue, Yang, Xinrui, Lu, Xingyu, Su, Dandan, Wang, Yidan, Wu, Huixing, Zhang, Zhenhua, Long, Changrui, Su, Liqian, Wang, Yanyu, Chen, Hongbo, Xiang, Shijian, Zhou, Benjie · 2025 · Biomaterials · DOI

Full title: PD-L1 antibody-modified plant-derived nanovesicles carrying a STING agonist for the combinational immunotherapy of melanoma

Authors: Xu, Zhanxue, Yang, Xinrui, Lu, Xingyu, Su, Dandan, Wang, Yidan, Wu, Huixing, Zhang, Zhenhua, Long, Changrui, Su, Liqian, Wang, Yanyu, Chen, Hongbo, Xiang, Shijian, Zhou, Benjie

Year: 2025

Venue: Biomaterials

DOI: https://doi.org/10.1016/j.biomaterials.2025.123396

Paper Immune checkpoint proteins: a new therapeutic paradigm for cancer--preclinical background: CTLA-4 and PD-1 blockade.

Weber, Jeffrey · 2010 · Seminars in oncology · DOI

Full title: Immune checkpoint proteins: a new therapeutic paradigm for cancer--preclinical background: CTLA-4 and PD-1 blockade.

Authors: Weber, Jeffrey

Year: 2010

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2010.09.005

Paper Ipilimumab plus nivolumab in patients with symptomatic melanoma brain metastasis requiring corticosteroids

Manacorda, Simona, Carmena, Maria De Toro, Malone, Ciara, Le, Ha Mo Linh, Furness, Andrew J.S., Larkin, James, Schmitt, Andreas M. · 2023 · European Journal of Cancer · DOI

Full title: Ipilimumab plus nivolumab in patients with symptomatic melanoma brain metastasis requiring corticosteroids

Authors: Manacorda, Simona, Carmena, Maria De Toro, Malone, Ciara, Le, Ha Mo Linh, Furness, Andrew J.S., Larkin, James, Schmitt, Andreas M.

Year: 2023

Venue: European Journal of Cancer

DOI: https://doi.org/10.1016/j.ejca.2023.04.018

Paper Anti-PD1 antibody enhances the anti-tumor efficacy of MUC1-MBP fusion protein vaccine via increasing Th1, Tc1 activity and decreasing the proportion of MDSC in the B16-MUC1 melanoma mouse model.

Zhang, Zenan, Zhou, Hongyue, Liu, Yu, Ren, Jia, Wang, Jingjing, Sang, Qianyu, Lan, Yue, Wu, Yixuan, Yuan, Hongyan, Ni, Weihua, Tai, Guixiang · 2021 · International immunopharmacology · DOI

Full title: Anti-PD1 antibody enhances the anti-tumor efficacy of MUC1-MBP fusion protein vaccine via increasing Th1, Tc1 activity and decreasing the proportion of MDSC in the B16-MUC1 melanoma mouse model.

Authors: Zhang, Zenan, Zhou, Hongyue, Liu, Yu, Ren, Jia, Wang, Jingjing, Sang, Qianyu, Lan, Yue, Wu, Yixuan, Yuan, Hongyan, Ni, Weihua, Tai, Guixiang

Year: 2021

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2021.108173

Paper Strategies for developing PD-1 inhibitors and future directions.

Chen, Wensheng, Huang, Yuan, Pan, Wenting, Xu, Meng, Chen, Liang · 2022 · Biochemical pharmacology · DOI

Full title: Strategies for developing PD-1 inhibitors and future directions.

Authors: Chen, Wensheng, Huang, Yuan, Pan, Wenting, Xu, Meng, Chen, Liang

Year: 2022

Venue: Biochemical pharmacology

DOI: https://doi.org/10.1016/j.bcp.2022.115113

Paper Combination Immunotherapy Approaches for Pancreatic Cancer Treatment.

Cheng, Xianliang, Zhao, Gang, Zhao, Yunqi · 2018 · Canadian journal of gastroenterology & hepatology · DOI

Full title: Combination Immunotherapy Approaches for Pancreatic Cancer Treatment.

Authors: Cheng, Xianliang, Zhao, Gang, Zhao, Yunqi

Year: 2018

Venue: Canadian journal of gastroenterology & hepatology

DOI: https://doi.org/10.1155/2018/6240467

Paper A multidisciplinary approach with immunotherapies for advanced hepatocellular carcinoma

Lee, Yu Rim · 2023 · Journal of Liver Cancer · DOI

Full title: A multidisciplinary approach with immunotherapies for advanced hepatocellular carcinoma

Authors: Lee, Yu Rim

Year: 2023

Venue: Journal of Liver Cancer

DOI: https://doi.org/10.17998/jlc.2023.09.04

Paper Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response.

Rupp, Tristan, Genest, Laurie, Babin, David, Legrand, Christophe, Hunault, Marion, Froget, Guillaume, Castagné, Vincent · 2022 · Translational oncology · DOI

Full title: Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response.

Authors: Rupp, Tristan, Genest, Laurie, Babin, David, Legrand, Christophe, Hunault, Marion, Froget, Guillaume, Castagné, Vincent

Year: 2022

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2022.101405

Paper Health-Related Quality of Life in the Era of Immune Checkpoint Blockade: What Do Patient-Reported Outcomes Reveal?

Dunker, Alexandra M, Malik, Neha, Krause, Kathryn J, Keung, Emily Z, Liu, Jason B, Nassif Haddad, Elise F, Somaiah, Neeta, Lyu, Heather G, Roland, Christina L · 2025 · Cancers · DOI

Full title: Health-Related Quality of Life in the Era of Immune Checkpoint Blockade: What Do Patient-Reported Outcomes Reveal?

Authors: Dunker, Alexandra M, Malik, Neha, Krause, Kathryn J, Keung, Emily Z, Liu, Jason B, Nassif Haddad, Elise F, Somaiah, Neeta, Lyu, Heather G, Roland, Christina L

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17243917

Paper Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining Immunogenic Cell Death Stimuli with Immune Modulatory Drugs.

A. Nel, Kuo-Ching Mei, Yu-Pei Liao, Xiangsheng Liu · 2022 · ACS Nano · DOI

Full title: Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining Immunogenic Cell Death Stimuli with Immune Modulatory Drugs.

Authors: A. Nel, Kuo-Ching Mei, Yu-Pei Liao, Xiangsheng Liu

Year: 2022

Venue: ACS Nano

DOI: https://doi.org/10.1021/acsnano.2c01252

Paper Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538.

Klein, Oliver, Senko, Clare, Carlino, Matteo S, Markman, Ben, Jackett, Louise, Gao, Bo, Lum, Caroline, Kee, Damien, Behren, Andreas, Palmer, Jodie, Cebon, Jonathan · 2021 · Oncoimmunology · DOI

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538.

Authors: Klein, Oliver, Senko, Clare, Carlino, Matteo S, Markman, Ben, Jackett, Louise, Gao, Bo, Lum, Caroline, Kee, Damien, Behren, Andreas, Palmer, Jodie, Cebon, Jonathan

Year: 2021

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2021.1908771

Paper Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities

Morrissey, KM, Yuraszeck, TM, Li, Chi‐Chung, Zhang, Y, Kasichayanula, Sreeneeranj · 2016 · Clinical and Translational Science · DOI

Full title: Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities

Authors: Morrissey, KM, Yuraszeck, TM, Li, Chi‐Chung, Zhang, Y, Kasichayanula, Sreeneeranj

Year: 2016

Venue: Clinical and Translational Science

DOI: https://doi.org/10.1111/cts.12391

Paper Imaging immune checkpoint networks in cancer tissues with supermultiplexed SERS nanoprobes.

Li, Jin, Liu, Fugang, Bi, Xinyuan, Ye, Jian · 2023 · Biomaterials · DOI

Full title: Imaging immune checkpoint networks in cancer tissues with supermultiplexed SERS nanoprobes.

Authors: Li, Jin, Liu, Fugang, Bi, Xinyuan, Ye, Jian

Year: 2023

Venue: Biomaterials

DOI: https://doi.org/10.1016/j.biomaterials.2023.122327

Paper Emerging insights into STK11, KEAP1 and KRAS mutations: implications for immunotherapy in patients with advanced non-small cell lung cancer.

Knetki-Wróblewska, Magdalena, Wojas-Krawczyk, Kamila, Krawczyk, Paweł, Krzakowski, Maciej · 2024 · Translational lung cancer research · DOI

Full title: Emerging insights into STK11, KEAP1 and KRAS mutations: implications for immunotherapy in patients with advanced non-small cell lung cancer.

Authors: Knetki-Wróblewska, Magdalena, Wojas-Krawczyk, Kamila, Krawczyk, Paweł, Krzakowski, Maciej

Year: 2024

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-24-552

Paper ABCB11 accumulated in immature tertiary lymphoid structures participates in xenobiotic metabolic process and predicts resistance to PD-1/PD-L1 inhibitors in head and neck squamous cell carcinoma.

Ning, Junya, Hao, Jie, Guo, Fengli, Hou, Xiukun, Li, Lijuan, Wang, Jinmiao, Wang, Shoujun, Gao, Ying, Zheng, Xiangqian, Gao, Ming · 2023 · Translational oncology · DOI

Full title: ABCB11 accumulated in immature tertiary lymphoid structures participates in xenobiotic metabolic process and predicts resistance to PD-1/PD-L1 inhibitors in head and neck squamous cell carcinoma.

Authors: Ning, Junya, Hao, Jie, Guo, Fengli, Hou, Xiukun, Li, Lijuan, Wang, Jinmiao, Wang, Shoujun, Gao, Ying, Zheng, Xiangqian, Gao, Ming

Year: 2023

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2023.101747

Paper Neoadjuvant immunotherapy based on PD-1/L1 inhibitors for gastrointestinal tumors: a review of the rationale and clinical advances

Dongxu Wang, Hui Liu, J. Tian, Daolin Zhang, Lun‐Jie Yan, Zi-Niu Ding, Han Li, Yu-Chuan Yan, Zhao-Ru Dong, Tao Li · 2024 · International Journal of Surgery · DOI

Full title: Neoadjuvant immunotherapy based on PD-1/L1 inhibitors for gastrointestinal tumors: a review of the rationale and clinical advances

Authors: Dongxu Wang, Hui Liu, J. Tian, Daolin Zhang, Lun‐Jie Yan, Zi-Niu Ding, Han Li, Yu-Chuan Yan, Zhao-Ru Dong, Tao Li

Year: 2024

Venue: International Journal of Surgery

DOI: https://doi.org/10.1097/js9.0000000000001357

Paper [CTIA-4 blockade therapy; biology and clinical activity].

Tada, Kohei, Heike, Yuji · 2017 · Nihon rinsho. Japanese journal of clinical medicine

Full title: [CTIA-4 blockade therapy; biology and clinical activity].

Authors: Tada, Kohei, Heike, Yuji

Year: 2017

Venue: Nihon rinsho. Japanese journal of clinical medicine

Paper CRISPR knock out CTLA-4 enhances the anti-tumor activity of cytotoxic T lymphocytes.

Shi, Long, Meng, Tongyu, Zhao, Zhilong, Han, Jinsheng, Zhang, Wei, Gao, Fei, Cai, Jianhui · 2017 · Gene · DOI

Full title: CRISPR knock out CTLA-4 enhances the anti-tumor activity of cytotoxic T lymphocytes.

Authors: Shi, Long, Meng, Tongyu, Zhao, Zhilong, Han, Jinsheng, Zhang, Wei, Gao, Fei, Cai, Jianhui

Year: 2017

Venue: Gene

DOI: https://doi.org/10.1016/j.gene.2017.09.010

Paper Abstract 88: Novel cell-based bioassays enable preclinical animal studies during immuno-oncology drug development

Jun Wang, D. Garvin, Aileen Paguio, Elizabeth Perrin, Jim Hartnett, M. Cong, Jamison J. Grailer · 2024 · Cancer Research · DOI

Full title: Abstract 88: Novel cell-based bioassays enable preclinical animal studies during immuno-oncology drug development

Authors: Jun Wang, D. Garvin, Aileen Paguio, Elizabeth Perrin, Jim Hartnett, M. Cong, Jamison J. Grailer

Year: 2024

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2024-88

Paper Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T cells.

Zhang, Zhen, Langenbach, Marlene, Sagar, Sagar, Fetsch, Viktor, Stritzker, Jonas, Severa, Elizabeth, Meng, Ke, Winkler, Frances, Rana, Nisha, Zoldan, Katharina, Godbole, Ira, Solis, Sabrina, Weber, Jeffrey S, Rafei-Shamsabadi, David, Lehr, Saskia, Diehl, Rebecca, Venhoff, Ana Cecilia, Voll, Reinhard E, Buettner, Nico, Neumann-Haefelin, Christoph, Boettler, Tobias, Hofmann, Maike, Boerries, Melanie, Meiss, Frank, Zeiser, Robert, Thimme, Robert, Herati, Ramin S, Bengsch, Bertram · 2025 · Nature immunology · DOI

Full title: Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T cells.

Authors: Zhang, Zhen, Langenbach, Marlene, Sagar, Sagar, Fetsch, Viktor, Stritzker, Jonas, Severa, Elizabeth, Meng, Ke, Winkler, Frances, Rana, Nisha, Zoldan, Katharina, Godbole, Ira, Solis, Sabrina, Weber, Jeffrey S, Rafei-Shamsabadi, David, Lehr, Saskia, Diehl, Rebecca, Venhoff, Ana Cecilia, Voll, Reinhard E, Buettner, Nico, Neumann-Haefelin, Christoph, Boettler, Tobias, Hofmann, Maike, Boerries, Melanie, Meiss, Frank, Zeiser, Robert, Thimme, Robert, Herati, Ramin S, Bengsch, Bertram

Year: 2025

Venue: Nature immunology

DOI: https://doi.org/10.1038/s41590-024-02027-0

Paper Systemic anti-CTLA-4 and intravesical Bacille-Calmette-Guerin therapy in non-muscle invasive bladder cancer: Is there a rationale of synergism?

Fahmy, Omar, Khairul-Asri, Mohd Ghani, Stenzl, Arnulf, Gakis, Georgios · 2016 · Medical hypotheses · DOI

Full title: Systemic anti-CTLA-4 and intravesical Bacille-Calmette-Guerin therapy in non-muscle invasive bladder cancer: Is there a rationale of synergism?

Authors: Fahmy, Omar, Khairul-Asri, Mohd Ghani, Stenzl, Arnulf, Gakis, Georgios

Year: 2016

Venue: Medical hypotheses

DOI: https://doi.org/10.1016/j.mehy.2016.04.037

Paper Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.

Kamran, Neha, Kadiyala, Padma, Saxena, Meghna, Candolfi, Marianela, Li, Youping, Moreno-Ayala, Mariela A, Raja, Nicholas, Shah, Diana, Lowenstein, Pedro R, Castro, Maria G · 2017 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.

Authors: Kamran, Neha, Kadiyala, Padma, Saxena, Meghna, Candolfi, Marianela, Li, Youping, Moreno-Ayala, Mariela A, Raja, Nicholas, Shah, Diana, Lowenstein, Pedro R, Castro, Maria G

Year: 2017

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1016/j.ymthe.2016.10.003

Paper Autoimmune Myocarditis Caused by Immune Checkpoint Inhibitors Treated With Antithymocyte Globulin

Jain, Varun, Mohebtash, Mahsa, Rodrigo, M.E., Ruiz, George, Atkins, Michael B., Barac, Ana · 2018 · Journal of Immunotherapy · DOI

Full title: Autoimmune Myocarditis Caused by Immune Checkpoint Inhibitors Treated With Antithymocyte Globulin

Authors: Jain, Varun, Mohebtash, Mahsa, Rodrigo, M.E., Ruiz, George, Atkins, Michael B., Barac, Ana

Year: 2018

Venue: Journal of Immunotherapy

DOI: https://doi.org/10.1097/cji.0000000000000239

Paper The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.

Poon, Edmund, Mullins, Stefanie, Watkins, Amanda, Williams, Geoffrey S, Koopmann, Jens-Oliver, Di Genova, Gianfranco, Cumberbatch, Marie, Veldman-Jones, Margaret, Grosskurth, Shaun E, Sah, Vasu, Schuller, Alwin, Reimer, Corrine, Dovedi, Simon J, Smith, Paul D, Stewart, Ross, Wilkinson, Robert W · 2017 · Journal for immunotherapy of cancer · DOI

Full title: The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.

Authors: Poon, Edmund, Mullins, Stefanie, Watkins, Amanda, Williams, Geoffrey S, Koopmann, Jens-Oliver, Di Genova, Gianfranco, Cumberbatch, Marie, Veldman-Jones, Margaret, Grosskurth, Shaun E, Sah, Vasu, Schuller, Alwin, Reimer, Corrine, Dovedi, Simon J, Smith, Paul D, Stewart, Ross, Wilkinson, Robert W

Year: 2017

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-017-0268-8

Paper Therapy of metastatic malignant melanoma: on the way to individualized disease control.

Vogt, Thomas · 2014 · Advances in experimental medicine and biology

Full title: Therapy of metastatic malignant melanoma: on the way to individualized disease control.

Authors: Vogt, Thomas

Year: 2014

Venue: Advances in experimental medicine and biology

Paper The quadruple immunotherapy for colorectal cancer (QuICC) trial for mismatch repair-proficient metastatic colorectal cancer.

Bracken-Clarke, Dara, Pastor, Danielle M, Marté, Jennifer L, Donahue, Renee N, Hodge, James W, Cordes, Lisa, Floudas, Charalampos S, Tschernia, Nicholas P, Karzai, Fatima, Brownell, Isaac, Turkbey, Evrim B, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Maeng, Hoyoung M, Strauss, Julius, Redman, Jason M · 2026 · The oncologist · DOI

Full title: The quadruple immunotherapy for colorectal cancer (QuICC) trial for mismatch repair-proficient metastatic colorectal cancer.

Authors: Bracken-Clarke, Dara, Pastor, Danielle M, Marté, Jennifer L, Donahue, Renee N, Hodge, James W, Cordes, Lisa, Floudas, Charalampos S, Tschernia, Nicholas P, Karzai, Fatima, Brownell, Isaac, Turkbey, Evrim B, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Maeng, Hoyoung M, Strauss, Julius, Redman, Jason M

Year: 2026

Venue: The oncologist

DOI: https://doi.org/10.1093/oncolo/oyag008

Paper Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma.

Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi · 2022 · Frontiers in chemistry · DOI

Full title: Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma.

Authors: Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi

Year: 2022

Venue: Frontiers in chemistry

DOI: https://doi.org/10.3389/fchem.2022.847621

Paper Metastatic lesion of a choroidal melanoma located in the head of pancreas.

Castro Rodríguez, Javier, Osuna Soto, Julio, Perdices López, Emilia Victoria · 2023 · Revista espanola de enfermedades digestivas · DOI

Full title: Metastatic lesion of a choroidal melanoma located in the head of pancreas.

Authors: Castro Rodríguez, Javier, Osuna Soto, Julio, Perdices López, Emilia Victoria

Year: 2023

Venue: Revista espanola de enfermedades digestivas

DOI: https://doi.org/10.17235/reed.2022.8843/2022

Paper Lung cancer: current therapies and new targeted treatments

Hirsch, Fred R., Scagliotti, Giorgio V., Mulshine, James L., Kwon, Regina, Curran, Walter J., Wu, Yi‐Long, Paz‐Ares, Luis · 2016 · The Lancet · DOI

Full title: Lung cancer: current therapies and new targeted treatments

Authors: Hirsch, Fred R., Scagliotti, Giorgio V., Mulshine, James L., Kwon, Regina, Curran, Walter J., Wu, Yi‐Long, Paz‐Ares, Luis

Year: 2016

Venue: The Lancet

DOI: https://doi.org/10.1016/s0140-6736(16)30958-8

Paper Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.

Wang, Kevin, Coutifaris, Paulina, Brocks, David, Wang, Guanning, Azar, Tarek, Solis, Sabrina, Nandi, Ajeya, Anderson, Shaneaka, Han, Nicholas, Manne, Sasikanth, Kiner, Evgeny, Sachar, Chirag, Lucas, Minke, George, Sangeeth, Yan, Patrick K, Kier, Melanie W, Laughlin, Amy I, Kothari, Shawn, Giles, Josephine, Mathew, Divij, Ghinnagow, Reem, Alanio, Cecile, Flowers, Ahron, Xu, Wei, Tenney, Daniel J, Xu, Xiaowei, Amaravadi, Ravi K, Karakousis, Giorgos C, Schuchter, Lynn M, Buggert, Marcus, Oldridge, Derek, Minn, Andy J, Blank, Christian, Weber, Jeffrey S, Mitchell, Tara C, Farwell, Michael D, Herati, Ramin S, Huang, Alexander C · 2024 · Cancer cell · DOI

Full title: Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.

Authors: Wang, Kevin, Coutifaris, Paulina, Brocks, David, Wang, Guanning, Azar, Tarek, Solis, Sabrina, Nandi, Ajeya, Anderson, Shaneaka, Han, Nicholas, Manne, Sasikanth, Kiner, Evgeny, Sachar, Chirag, Lucas, Minke, George, Sangeeth, Yan, Patrick K, Kier, Melanie W, Laughlin, Amy I, Kothari, Shawn, Giles, Josephine, Mathew, Divij, Ghinnagow, Reem, Alanio, Cecile, Flowers, Ahron, Xu, Wei, Tenney, Daniel J, Xu, Xiaowei, Amaravadi, Ravi K, Karakousis, Giorgos C, Schuchter, Lynn M, Buggert, Marcus, Oldridge, Derek, Minn, Andy J, Blank, Christian, Weber, Jeffrey S, Mitchell, Tara C, Farwell, Michael D, Herati, Ramin S, Huang, Alexander C

Year: 2024

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2024.08.007

Paper Nivolumab Plus Relatlimab: First Approval.

Paik, Julia · 2022 · Drugs · DOI

Full title: Nivolumab Plus Relatlimab: First Approval.

Authors: Paik, Julia

Year: 2022

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-022-01723-1

Paper Deciphering primary and acquired immunotherapy resistance with whole genome and transcriptome analysis (WGTA).

S. Genta, J. Bruce, Xuan Li, Sam Felicen, A. A. Abdul Razak, S. Saibil, M. Butler, P. Bedard, Bernard Lam, M. Tsao, W. Leong, A. Easson, Ben X Wang, I. Lungu, D. Goldstein, A. Hansen, L. Eng, Trevor J Pugh, L. Siu, A. Spreafico · 2023 · Journal of Clinical Oncology · DOI

Full title: Deciphering primary and acquired immunotherapy resistance with whole genome and transcriptome analysis (WGTA).

Authors: S. Genta, J. Bruce, Xuan Li, Sam Felicen, A. A. Abdul Razak, S. Saibil, M. Butler, P. Bedard, Bernard Lam, M. Tsao, W. Leong, A. Easson, Ben X Wang, I. Lungu, D. Goldstein, A. Hansen, L. Eng, Trevor J Pugh, L. Siu, A. Spreafico

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.16_suppl.2602

Paper [Renal injury during combination immunotherapy (ipilimumab + nivolumab) in patients with metastatic renal cell cancer who previously underwent nephrectomy].

Titov K.S. Titov, Epifanova M.V. Epifanova, A. A. Alimov, Nesterova O.Yu. Nesterova, S. V. Shutov, Lebedev S.S. Lebedev · 2025 · Urologiia · DOI

Full title: [Renal injury during combination immunotherapy (ipilimumab + nivolumab) in patients with metastatic renal cell cancer who previously underwent nephrectomy].

Authors: Titov K.S. Titov, Epifanova M.V. Epifanova, A. A. Alimov, Nesterova O.Yu. Nesterova, S. V. Shutov, Lebedev S.S. Lebedev

Year: 2025

Venue: Urologiia

DOI: https://doi.org/10.18565/urology.2025.1.68-74

Paper Comparison between PD-1/PD-L1 inhibitors (nivolumab, pembrolizumab, and atezolizumab) in pretreated NSCLC patients: Evidence from a Bayesian network model.

Wu, Yingcheng, Lin, Lifeng, Shen, Yanting, Wu, Huiqun · 2018 · International journal of cancer · DOI

Full title: Comparison between PD-1/PD-L1 inhibitors (nivolumab, pembrolizumab, and atezolizumab) in pretreated NSCLC patients: Evidence from a Bayesian network model.

Authors: Wu, Yingcheng, Lin, Lifeng, Shen, Yanting, Wu, Huiqun

Year: 2018

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.31733

Paper Immunologic effects of locoregional therapies for unresectable hepatocellular carcinoma.

Schmidt, Robin, Gebauer, Bernhard, Akbari, Nilufar, Roderburg, Christoph, Torsello, Giovanni Federico, Fehrenbach, Uli, Auer, Timo Alexander, Mohr, Raphael, Ardila Pardo, Gracia Lana, Lim, Winna, Pivetta, Fabio, Can, Elif, Hamm, Charlie Alexander, Tacke, Frank, Hamm, Bernd, Hammerich, Linda, Savic, Lynn Jeanette · 2025 · JHEP reports : innovation in hepatology · DOI

Full title: Immunologic effects of locoregional therapies for unresectable hepatocellular carcinoma.

Authors: Schmidt, Robin, Gebauer, Bernhard, Akbari, Nilufar, Roderburg, Christoph, Torsello, Giovanni Federico, Fehrenbach, Uli, Auer, Timo Alexander, Mohr, Raphael, Ardila Pardo, Gracia Lana, Lim, Winna, Pivetta, Fabio, Can, Elif, Hamm, Charlie Alexander, Tacke, Frank, Hamm, Bernd, Hammerich, Linda, Savic, Lynn Jeanette

Year: 2025

Venue: JHEP reports : innovation in hepatology

DOI: https://doi.org/10.1016/j.jhepr.2025.101555

Paper Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors.

Timnik, Vincent R, Zoeschg, Andreas, Diederich, Sarah, Nefzger, Sophie M, Huang, Ziyi, Schmid, Nicole A, Giller, Maximilian, Steiger, Katja, Combs, Stephanie E, Kroemer, Guido, Schmid, Thomas E, Fischer, Julius C · 2025 · International journal of radiation oncology, biology, physics · DOI

Full title: Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors.

Authors: Timnik, Vincent R, Zoeschg, Andreas, Diederich, Sarah, Nefzger, Sophie M, Huang, Ziyi, Schmid, Nicole A, Giller, Maximilian, Steiger, Katja, Combs, Stephanie E, Kroemer, Guido, Schmid, Thomas E, Fischer, Julius C

Year: 2025

Venue: International journal of radiation oncology, biology, physics

DOI: https://doi.org/10.1016/j.ijrobp.2025.04.008

Paper Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironment

Zeng, Yang, Li, Binghao, Liang, Yingying, Reeves, Patrick M., Qu, Xiying, Ran, Chongzhao, Liu, Qiuyan, Callahan, Michael V., Sluder, Ann E., Gelfand, Jeffrey A., Chen, Huabiao, Poznansky, Mark C. · 2019 · The FASEB Journal · DOI

Full title: Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironment

Authors: Zeng, Yang, Li, Binghao, Liang, Yingying, Reeves, Patrick M., Qu, Xiying, Ran, Chongzhao, Liu, Qiuyan, Callahan, Michael V., Sluder, Ann E., Gelfand, Jeffrey A., Chen, Huabiao, Poznansky, Mark C.

Year: 2019

Venue: The FASEB Journal

DOI: https://doi.org/10.1096/fj.201802067rr

Paper Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.

Slovak, Ryan J, Park, Hong-Jai, Kamp, William M, Ludwig, Johannes M, Kang, Insoo, Kim, Hyun S · 2021 · Scientific reports · DOI

Full title: Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.

Authors: Slovak, Ryan J, Park, Hong-Jai, Kamp, William M, Ludwig, Johannes M, Kang, Insoo, Kim, Hyun S

Year: 2021

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-021-85810-5

Paper A Population-Level Real-World Analysis and Single-Center Validation of Melanoma Brain Metastasis Epidemiology following Dual-Agent Immunotherapy.

Bhanja, Debarati, Zhu, Junjia, Wilding, Hannah, Benavides-Vasquez, Jorge, de Macedo Filho, Leonardo, Ozair, Ahmad, Moeckel, Camille, Badani, Aarav, Hong, Jinpyo, Sivik, Jeffrey, Drabick, Joseph J, Pameijer, Colette R, Margolin, Kim, Ahluwalia, Manmeet, Mansouri, Alireza · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: A Population-Level Real-World Analysis and Single-Center Validation of Melanoma Brain Metastasis Epidemiology following Dual-Agent Immunotherapy.

Authors: Bhanja, Debarati, Zhu, Junjia, Wilding, Hannah, Benavides-Vasquez, Jorge, de Macedo Filho, Leonardo, Ozair, Ahmad, Moeckel, Camille, Badani, Aarav, Hong, Jinpyo, Sivik, Jeffrey, Drabick, Joseph J, Pameijer, Colette R, Margolin, Kim, Ahluwalia, Manmeet, Mansouri, Alireza

Year: 2025

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-24-2681

Paper DNA damage response as biomarkers informing a precision medicine approach to bladder cancer: what are the next steps?

Scot A. Niglio, M. Galsky · 2018 · Expert Review of Precision Medicine and Drug Development · DOI

Full title: DNA damage response as biomarkers informing a precision medicine approach to bladder cancer: what are the next steps?

Authors: Scot A. Niglio, M. Galsky

Year: 2018

Venue: Expert Review of Precision Medicine and Drug Development

DOI: https://doi.org/10.1080/23808993.2019.1539621

Paper Novel immunotherapy combinations for genitourinary cancers.

Al Harthy, Munjid, Redman, Jason, Madan, Ravi A · 2020 · Expert opinion on biological therapy · DOI

Full title: Novel immunotherapy combinations for genitourinary cancers.

Authors: Al Harthy, Munjid, Redman, Jason, Madan, Ravi A

Year: 2020

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2020.1713086

Paper Integrating CTLA-4/PD-1 blockade into cervical cancer management: Results of COMPASSION-16.

How, Jeffrey A, Jazaeri, Amir A · 2025 · Med (New York, N.Y.) · DOI

Full title: Integrating CTLA-4/PD-1 blockade into cervical cancer management: Results of COMPASSION-16.

Authors: How, Jeffrey A, Jazaeri, Amir A

Year: 2025

Venue: Med (New York, N.Y.)

DOI: https://doi.org/10.1016/j.medj.2024.11.011

Paper Is there any place for PD-1/CTLA-4 inhibitors combination in the first-line treatment of advanced NSCLC?-a trial-level meta-analysis in PD-L1 selected subgroups.

Passiglia, Francesco, Galvano, Antonio, Gristina, Valerio, Barraco, Nadia, Castiglia, Marta, Perez, Alessandro, La Mantia, Maria, Russo, Antonio, Bazan, Viviana · 2021 · Translational lung cancer research · DOI

Full title: Is there any place for PD-1/CTLA-4 inhibitors combination in the first-line treatment of advanced NSCLC?-a trial-level meta-analysis in PD-L1 selected subgroups.

Authors: Passiglia, Francesco, Galvano, Antonio, Gristina, Valerio, Barraco, Nadia, Castiglia, Marta, Perez, Alessandro, La Mantia, Maria, Russo, Antonio, Bazan, Viviana

Year: 2021

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-21-52

Paper Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.

Chantharasamee, Jomjit, Adashek, Jacob J, Wong, Karlton, Eckardt, Mark A, Chmielowski, Bartosz, Dry, Sarah, Eilber, Fritz C, Singh, Arun S · 2021 · Current treatment options in oncology · DOI

Full title: Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.

Authors: Chantharasamee, Jomjit, Adashek, Jacob J, Wong, Karlton, Eckardt, Mark A, Chmielowski, Bartosz, Dry, Sarah, Eilber, Fritz C, Singh, Arun S

Year: 2021

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-020-00806-z

Paper Immune checkpoint inhibitors in gynecologic cancers with lessons learned from non-gynecologic cancers.

Menderes, Gulden, Hicks, Christopher, Black, Jonathan D, Schwab, Carlton L, Santin, Alessandro D · 2016 · Expert opinion on biological therapy · DOI

Full title: Immune checkpoint inhibitors in gynecologic cancers with lessons learned from non-gynecologic cancers.

Authors: Menderes, Gulden, Hicks, Christopher, Black, Jonathan D, Schwab, Carlton L, Santin, Alessandro D

Year: 2016

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2016.1177018

Paper The adverse events associated with combination immunotherapy in cancers: Challenges and chances.

Zhuo, Minglei, Chi, Yujia, Wang, Ziping · 2020 · Asia-Pacific journal of clinical oncology · DOI

Full title: The adverse events associated with combination immunotherapy in cancers: Challenges and chances.

Authors: Zhuo, Minglei, Chi, Yujia, Wang, Ziping

Year: 2020

Venue: Asia-Pacific journal of clinical oncology

DOI: https://doi.org/10.1111/ajco.13365

Paper Gastrointestinal adverse events with combination of checkpoint inhibitors in advanced melanoma: a systematic review.

Mearns, Elizabeth S, Bell, Jill A, Galaznik, Aaron, Puglielli, Stefanie M, Cichewicz, Allie B, Boulanger, Talia, Garcia-Ribas, Ignacio · 2018 · Melanoma management · DOI

Full title: Gastrointestinal adverse events with combination of checkpoint inhibitors in advanced melanoma: a systematic review.

Authors: Mearns, Elizabeth S, Bell, Jill A, Galaznik, Aaron, Puglielli, Stefanie M, Cichewicz, Allie B, Boulanger, Talia, Garcia-Ribas, Ignacio

Year: 2018

Venue: Melanoma management

DOI: https://doi.org/10.2217/mmt-2017-0027

Paper Immunotherapy in Combination with Chemotherapy for Triple-negative Breast Cancer.

Elizabeth, Melendez Solano, Cristina, Stevens Barrón Jazmín, Christian, Chapa González · 2024 · Mini reviews in medicinal chemistry · DOI

Full title: Immunotherapy in Combination with Chemotherapy for Triple-negative Breast Cancer.

Authors: Elizabeth, Melendez Solano, Cristina, Stevens Barrón Jazmín, Christian, Chapa González

Year: 2024

Venue: Mini reviews in medicinal chemistry

DOI: https://doi.org/10.2174/1389557523666230517152538

Paper [Immunotherapy with immune checkpoint inhibitor and skin toxicity].

Simand, Pierre-François, Berthod, Grégoire, Parmentier, Laurent, Anchisi, Sandro · 2020 · Revue medicale suisse

Full title: [Immunotherapy with immune checkpoint inhibitor and skin toxicity].

Authors: Simand, Pierre-François, Berthod, Grégoire, Parmentier, Laurent, Anchisi, Sandro

Year: 2020

Venue: Revue medicale suisse

Paper Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade.

Vaccari, Monica, Boasso, Adriano, Fenizia, Claudio, Fuchs, Dietmar, Hryniewicz, Anna, Morgan, Tia, Weiss, Deborah, Doster, Melvin N, Heraud, Jean Michel, Shearer, Gene M, Franchini, Genoveffa · 2012 · Journal of virology · DOI

Full title: Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade.

Authors: Vaccari, Monica, Boasso, Adriano, Fenizia, Claudio, Fuchs, Dietmar, Hryniewicz, Anna, Morgan, Tia, Weiss, Deborah, Doster, Melvin N, Heraud, Jean Michel, Shearer, Gene M, Franchini, Genoveffa

Year: 2012

Venue: Journal of virology

DOI: https://doi.org/10.1128/JVI.05609-11

Paper Characterization of a Pyroptosis-Related Signature for Prognosis Prediction and Immune Microenvironment Infiltration in Prostate Cancer.

Zhang, Guian, Luo, Yong, Dong, Weimin, Zhong, Weide · 2022 · Computational and mathematical methods in medicine · DOI

Full title: Characterization of a Pyroptosis-Related Signature for Prognosis Prediction and Immune Microenvironment Infiltration in Prostate Cancer.

Authors: Zhang, Guian, Luo, Yong, Dong, Weimin, Zhong, Weide

Year: 2022

Venue: Computational and mathematical methods in medicine

DOI: https://doi.org/10.1155/2022/8233840

Paper Targeting the programmed cell death-1 pathway in breast and ovarian cancer

Emens, Leisha A., Kok, Marleen, Ojalvo, Laureen S. · 2016 · Current Opinion in Obstetrics & Gynecology · DOI

Full title: Targeting the programmed cell death-1 pathway in breast and ovarian cancer

Authors: Emens, Leisha A., Kok, Marleen, Ojalvo, Laureen S.

Year: 2016

Venue: Current Opinion in Obstetrics & Gynecology

DOI: https://doi.org/10.1097/gco.0000000000000257

Paper Anti-tumor immunological response induced by cryoablation and anti-CTLA-4 antibody in an in vivo RM-1 cell prostate cancer murine model.

Li, F, Guo, Z, Yu, H, Zhang, X, Si, T, Liu, C, Yang, X, Qi, L · 2014 · Neoplasma · DOI

Full title: Anti-tumor immunological response induced by cryoablation and anti-CTLA-4 antibody in an in vivo RM-1 cell prostate cancer murine model.

Authors: Li, F, Guo, Z, Yu, H, Zhang, X, Si, T, Liu, C, Yang, X, Qi, L

Year: 2014

Venue: Neoplasma

DOI: https://doi.org/10.4149/neo_2014_081

Paper Advanced Renal Cell Cancer Combination Immunotherapy Clinical Trial (ARCITECT; HCRN GU 22-587)

Serzan, Michael · 2024 · The Oncologist · DOI

Full title: Advanced Renal Cell Cancer Combination Immunotherapy Clinical Trial (ARCITECT; HCRN GU 22-587)

Authors: Serzan, Michael

Year: 2024

Venue: The Oncologist

DOI: https://doi.org/10.1093/oncolo/oyae181.018

Paper [Immune-related adverse events after immune checkpoints inhibitors in 2019: An update].

Comont, T, Belliere, J, Sibaud, V, Alric, L, Meyer, N, Mazières, J, Caron, P, Acket, B, Michot, J-M, Beyne-Rauzy, O, Lambotte, O · 2020 · La Revue de medecine interne · DOI

Full title: [Immune-related adverse events after immune checkpoints inhibitors in 2019: An update].

Authors: Comont, T, Belliere, J, Sibaud, V, Alric, L, Meyer, N, Mazières, J, Caron, P, Acket, B, Michot, J-M, Beyne-Rauzy, O, Lambotte, O

Year: 2020

Venue: La Revue de medecine interne

DOI: https://doi.org/10.1016/j.revmed.2019.09.005

Paper Evaluating Toxicity and Interaction Outcomes of Systemic Therapy and Stereotactic Ablative Radiation Therapy for Oligometastatic Disease: A Secondary Analysis of the Phase 2 SABR-5 Trial.

Kooyman, Aiden, Chang, Jee Suk, Liu, Mitchell, Jiang, Will, Bergman, Alanah, Schellenberg, Devin, Mou, Benjamin, Alexander, Abraham, Carolan, Hannah, Hsu, Fred, Miller, Stacy, Atrchian, Siavash, Chan, Elisa, Ho, Clement, Mohamed, Islam, Lin, Angela, Berrang, Tanya, Bang, Andrew, Chng, Nick, Matthews, Quinn, Huang, Vicky, Mestrovic, Ante, Hyde, Derek, Lund, Chad, Pai, Howard, Valev, Boris, Lefresne, Shilo, Tyldesley, Scott, Olson, Robert, Baker, Sarah · 2025 · International journal of radiation oncology, biology, physics · DOI

Full title: Evaluating Toxicity and Interaction Outcomes of Systemic Therapy and Stereotactic Ablative Radiation Therapy for Oligometastatic Disease: A Secondary Analysis of the Phase 2 SABR-5 Trial.

Authors: Kooyman, Aiden, Chang, Jee Suk, Liu, Mitchell, Jiang, Will, Bergman, Alanah, Schellenberg, Devin, Mou, Benjamin, Alexander, Abraham, Carolan, Hannah, Hsu, Fred, Miller, Stacy, Atrchian, Siavash, Chan, Elisa, Ho, Clement, Mohamed, Islam, Lin, Angela, Berrang, Tanya, Bang, Andrew, Chng, Nick, Matthews, Quinn, Huang, Vicky, Mestrovic, Ante, Hyde, Derek, Lund, Chad, Pai, Howard, Valev, Boris, Lefresne, Shilo, Tyldesley, Scott, Olson, Robert, Baker, Sarah

Year: 2025

Venue: International journal of radiation oncology, biology, physics

DOI: https://doi.org/10.1016/j.ijrobp.2025.03.079

Paper Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma.

Cheng, Ann-Lii, Hsu, Chiun, Chan, Stephen L, Choo, Su-Pin, Kudo, Masatoshi · 2020 · Journal of hepatology · DOI

Full title: Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma.

Authors: Cheng, Ann-Lii, Hsu, Chiun, Chan, Stephen L, Choo, Su-Pin, Kudo, Masatoshi

Year: 2020

Venue: Journal of hepatology

DOI: https://doi.org/10.1016/j.jhep.2019.09.025

Paper Harnessing the immune system for the treatment of melanoma: current status and future prospects.

Guennoun, Andrea, Sidahmed, Heba, Maccalli, Cristina, Seliger, Barbara, Marincola, Francesco M, Bedognetti, Davide · 2016 · Expert review of clinical immunology · DOI

Full title: Harnessing the immune system for the treatment of melanoma: current status and future prospects.

Authors: Guennoun, Andrea, Sidahmed, Heba, Maccalli, Cristina, Seliger, Barbara, Marincola, Francesco M, Bedognetti, Davide

Year: 2016

Venue: Expert review of clinical immunology

DOI: https://doi.org/10.1080/1744666X.2016.1176529

Paper Differential shaping of T cell responses elicited by heterologous ChAd68/self-amplifying mRNA SIV vaccine in macaques in combination with αCTLA4, αPD-1, or FLT3R agonist.

Rappaport, Amy R, Bekerman, Elena, Boucher, Gregory R, Sung, Janette, Carr, Brian, Corzo, Cesar A, Larson, Heather, Kachura, Melissa A, Scallan, Ciaran D, Geleziunas, Romas, SenGupta, Devi, Jooss, Karin · 2025 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Differential shaping of T cell responses elicited by heterologous ChAd68/self-amplifying mRNA SIV vaccine in macaques in combination with αCTLA4, αPD-1, or FLT3R agonist.

Authors: Rappaport, Amy R, Bekerman, Elena, Boucher, Gregory R, Sung, Janette, Carr, Brian, Corzo, Cesar A, Larson, Heather, Kachura, Melissa A, Scallan, Ciaran D, Geleziunas, Romas, SenGupta, Devi, Jooss, Karin

Year: 2025

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.1093/jimmun/vkae052

Paper Cancer immunotherapy highlights from the 2014 ASCO Meeting.

Harshman, Lauren C, Drake, Charles G, Wargo, Jennifer A, Sharma, Padmanee, Bhardwaj, Nina · 2014 · Cancer immunology research · DOI

Full title: Cancer immunotherapy highlights from the 2014 ASCO Meeting.

Authors: Harshman, Lauren C, Drake, Charles G, Wargo, Jennifer A, Sharma, Padmanee, Bhardwaj, Nina

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0119

Paper PCN202 How Should VALUE be Attributed to the Constituent Parts of Combination Immunotherapy in NON-SMALL Cell LUNG Cancer?

R. Zaim, K. Redekop, C. D. Groot · 2020 · Value in Health · DOI

Full title: PCN202 How Should VALUE be Attributed to the Constituent Parts of Combination Immunotherapy in NON-SMALL Cell LUNG Cancer?

Authors: R. Zaim, K. Redekop, C. D. Groot

Year: 2020

Venue: Value in Health

DOI: https://doi.org/10.1016/j.jval.2020.08.339

Paper Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions.

Hassel, Jessica C, Heinzerling, Lucie, Aberle, Jens, Bähr, Oliver, Eigentler, Thomas K, Grimm, Marc-Oliver, Grünwald, Victor, Leipe, Jan, Reinmuth, Niels, Tietze, Julia K, Trojan, Jörg, Zimmer, Lisa, Gutzmer, Ralf · 2017 · Cancer treatment reviews · DOI

Full title: Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions.

Authors: Hassel, Jessica C, Heinzerling, Lucie, Aberle, Jens, Bähr, Oliver, Eigentler, Thomas K, Grimm, Marc-Oliver, Grünwald, Victor, Leipe, Jan, Reinmuth, Niels, Tietze, Julia K, Trojan, Jörg, Zimmer, Lisa, Gutzmer, Ralf

Year: 2017

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2017.05.003

Paper Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator.

Xiao, Qingqing, Li, Xiaotong, Liu, Chang, Jiang, Yuxin, He, Yonglong, Zhang, Wanting, Azevedo, Helena S, Wu, Wei, Xia, Yuanzheng, He, Wei · 2023 · Acta pharmaceutica Sinica. B · DOI

Full title: Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator.

Authors: Xiao, Qingqing, Li, Xiaotong, Liu, Chang, Jiang, Yuxin, He, Yonglong, Zhang, Wanting, Azevedo, Helena S, Wu, Wei, Xia, Yuanzheng, He, Wei

Year: 2023

Venue: Acta pharmaceutica Sinica. B

DOI: https://doi.org/10.1016/j.apsb.2022.07.012

Paper P537 Steroid use in patients with immune checkpoint inhibitor colitis

L. Crothers-Stomps, W. Mohsen, P. Kakkadasam Ramaswamy, R. Mason, M. Dzienis, J. Edwards · 2022 · Journal of Crohn's & Colitis · DOI

Full title: P537 Steroid use in patients with immune checkpoint inhibitor colitis

Authors: L. Crothers-Stomps, W. Mohsen, P. Kakkadasam Ramaswamy, R. Mason, M. Dzienis, J. Edwards

Year: 2022

Venue: Journal of Crohn's & Colitis

DOI: https://doi.org/10.1093/ecco-jcc/jjab232.664

Paper Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.

Galon, Jérôme, Bruni, Daniela · 2019 · Nature reviews. Drug discovery · DOI

Full title: Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.

Authors: Galon, Jérôme, Bruni, Daniela

Year: 2019

Venue: Nature reviews. Drug discovery

DOI: https://doi.org/10.1038/s41573-018-0007-y

Paper Single versus combination immunotherapy drug treatment in melanoma

Grimaldi, Antonio Maria, Marincola, Francesco M., Ascierto, Paolo A. · 2015 · Expert Opinion on Biological Therapy · DOI

Full title: Single versus combination immunotherapy drug treatment in melanoma

Authors: Grimaldi, Antonio Maria, Marincola, Francesco M., Ascierto, Paolo A.

Year: 2015

Venue: Expert Opinion on Biological Therapy

DOI: https://doi.org/10.1517/14712598.2016.1128891

Paper Combined treatment of durvalumab, bevacizumab and tremelimumab in subjects with hepatocellular carcinoma (HCC) or biliary tract carcinoma (BTC).

Joy A Awosika, M. C. Monge B., Changqing Xie, Nebojsa Skorupan, David E. Kleiner, Donna Mabry Hrones, Bradford J Wood, B. Redd, T. F. Greten · 2025 · Journal of Clinical Oncology · DOI

Full title: Combined treatment of durvalumab, bevacizumab and tremelimumab in subjects with hepatocellular carcinoma (HCC) or biliary tract carcinoma (BTC).

Authors: Joy A Awosika, M. C. Monge B., Changqing Xie, Nebojsa Skorupan, David E. Kleiner, Donna Mabry Hrones, Bradford J Wood, B. Redd, T. F. Greten

Year: 2025

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2025.43.16_suppl.4081

Paper Current and Future Aspects of Immunotherapy for Esophageal and Gastric Malignancies.

De Mello, Ramon Andrade, Lordick, Florian, Muro, Kei, Janjigian, Yelena Y · 2019 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Current and Future Aspects of Immunotherapy for Esophageal and Gastric Malignancies.

Authors: De Mello, Ramon Andrade, Lordick, Florian, Muro, Kei, Janjigian, Yelena Y

Year: 2019

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.1200/EDBK_236699

Paper TMIC-63. DUAL IMMUNE CHECKPOINT BLOCKADE IN A NOVEL EGFR-DRIVEN MURINE GLIOMA MODEL INCREASES PERIPHERAL T CELL PROLIFERATION BUT FAILS TO PROLONG SURVIVAL

Marissa Li, M. Pioso, J. Breunig, K. Grausam, D. Nathanson, R. Prins · 2024 · Neuro-Oncology · DOI

Full title: TMIC-63. DUAL IMMUNE CHECKPOINT BLOCKADE IN A NOVEL EGFR-DRIVEN MURINE GLIOMA MODEL INCREASES PERIPHERAL T CELL PROLIFERATION BUT FAILS TO PROLONG SURVIVAL

Authors: Marissa Li, M. Pioso, J. Breunig, K. Grausam, D. Nathanson, R. Prins

Year: 2024

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noae165.1241

Paper Comment on ‘Toxicities associated with immune checkpoint inhibitors: A systematic study’

Mohammad-Salar Hosseini, F. Jahanshahlou · 2023 · International Journal of Surgery · DOI

Full title: Comment on ‘Toxicities associated with immune checkpoint inhibitors: A systematic study’

Authors: Mohammad-Salar Hosseini, F. Jahanshahlou

Year: 2023

Venue: International Journal of Surgery

DOI: https://doi.org/10.1097/js9.0000000000000478

Paper Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells.

Kim, KiBem, Skora, Andrew D, Li, Zhaobo, Liu, Qiang, Tam, Ada J, Blosser, Richard L, Diaz, Luis A, Papadopoulos, Nickolas, Kinzler, Kenneth W, Vogelstein, Bert, Zhou, Shibin · 2014 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells.

Authors: Kim, KiBem, Skora, Andrew D, Li, Zhaobo, Liu, Qiang, Tam, Ada J, Blosser, Richard L, Diaz, Luis A, Papadopoulos, Nickolas, Kinzler, Kenneth W, Vogelstein, Bert, Zhou, Shibin

Year: 2014

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1410626111

Paper Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Planchard, David, Popat, Sanjay, Kerr, Keith M., Novello, Silvia, Smit, Egbert F., Faivre‐Finn, Corinne, Mok, Tony, Reck, Martin, Schil, Paul E. Van, Hellmann, Matthew D., Peters, Solange · 2018 · Annals of Oncology · DOI

Full title: Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Authors: Planchard, David, Popat, Sanjay, Kerr, Keith M., Novello, Silvia, Smit, Egbert F., Faivre‐Finn, Corinne, Mok, Tony, Reck, Martin, Schil, Paul E. Van, Hellmann, Matthew D., Peters, Solange

Year: 2018

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdy275

Paper Combinational immunotherapy based on immune checkpoints inhibitors in small cell lung cancer: is this the beginning to reverse the refractory situation?

Guo, Haoyue, He, Yayi, Chen, Peixin, Wang, Lei, Li, Wei, Chen, Bin, Liu, Yu, Wang, Hao, Zhao, Sha, Zhou, Caicun · 2020 · Journal of thoracic disease · DOI

Full title: Combinational immunotherapy based on immune checkpoints inhibitors in small cell lung cancer: is this the beginning to reverse the refractory situation?

Authors: Guo, Haoyue, He, Yayi, Chen, Peixin, Wang, Lei, Li, Wei, Chen, Bin, Liu, Yu, Wang, Hao, Zhao, Sha, Zhou, Caicun

Year: 2020

Venue: Journal of thoracic disease

DOI: https://doi.org/10.21037/jtd-20-1689

Paper Recovery from secondary adrenal insufficiency in a patient with immune checkpoint inhibitor therapy induced hypophysitis.

Thapi, Sahityasri, Leiter, Amanda, Galsky, Matthew, Gallagher, Emily J · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Recovery from secondary adrenal insufficiency in a patient with immune checkpoint inhibitor therapy induced hypophysitis.

Authors: Thapi, Sahityasri, Leiter, Amanda, Galsky, Matthew, Gallagher, Emily J

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0729-3

Paper Intratumoral CD16+ macrophages are associated with clinical outcomes of patients with metastatic melanoma treated with combination anti-PD-1 and anti-CTLA-4 therapy.

Hansol Lee, A. Ferguson, C. Quek, I. Vergara, Ines Pires daSilva, Ruth O Allen, T. Gide, J. Conway, L. Koufariotis, N. Hayward, N. Waddell, M. Carlino, A. Menzies, R. Saw, E. Shklovskaya, H. Rizos, S. Lo, R. Scolyer, G. Long, U. Palendira, J. Wilmott · 2023 · Clinical Cancer Research · DOI

Full title: Intratumoral CD16+ macrophages are associated with clinical outcomes of patients with metastatic melanoma treated with combination anti-PD-1 and anti-CTLA-4 therapy.

Authors: Hansol Lee, A. Ferguson, C. Quek, I. Vergara, Ines Pires daSilva, Ruth O Allen, T. Gide, J. Conway, L. Koufariotis, N. Hayward, N. Waddell, M. Carlino, A. Menzies, R. Saw, E. Shklovskaya, H. Rizos, S. Lo, R. Scolyer, G. Long, U. Palendira, J. Wilmott

Year: 2023

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-22-2657

Paper Combination immune checkpoint inhibitor therapy nivolumab and ipilimumab associated with multiple endocrinopathies

Gunawan, Florence, George, Elizabeth, Roberts, Adam · 2018 · Endocrinology Diabetes and Metabolism Case Reports · DOI

Full title: Combination immune checkpoint inhibitor therapy nivolumab and ipilimumab associated with multiple endocrinopathies

Authors: Gunawan, Florence, George, Elizabeth, Roberts, Adam

Year: 2018

Venue: Endocrinology Diabetes and Metabolism Case Reports

DOI: https://doi.org/10.1530/edm-17-0146

Paper Thinking Outside the Field: Two Cases of RT+ICI Synergy in Melanoma

Davidson, Tara M., Zhang, Henan, Dong, Haidong, Grams, Michael P., Park, Sean S., Yan, Yiyi · 2021 · Research Square (Research Square) · DOI

Full title: Thinking Outside the Field: Two Cases of RT+ICI Synergy in Melanoma

Authors: Davidson, Tara M., Zhang, Henan, Dong, Haidong, Grams, Michael P., Park, Sean S., Yan, Yiyi

Year: 2021

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-455431/v1

Paper Pneumonitis in Patients Treated With Anti–Programmed Death-1/Programmed Death Ligand 1 Therapy

Naidoo, Jarushka, Wang, Xuan, Woo, Kaitlin M., Iyriboz, Tunç, Halpenny, Darragh, Cunningham, Jane, Chaft, Jamie E., Segal, Neil H., Callahan, Margaret K., Lesokhin, Alexander M., Rosenberg, Jonathan E., Voss, Martin H., Rudin, Charles M., Rizvi, Hira, Hou, Xue, Rodríguez, Katherine, Albano, Melanie, Gordon, Ruth-Ann, Leduc, Charles, Rekhtman, Natasha, Harris, Bianca, Menzies, Alexander M., Guminski, Alexander, Carlino, Matteo S., Kong, Benjamin Y., Wolchok, Jedd D., Postow, Michael A., Long, Georgina V., Hellmann, Matthew D. · 2016 · Journal of Clinical Oncology · DOI

Full title: Pneumonitis in Patients Treated With Anti–Programmed Death-1/Programmed Death Ligand 1 Therapy

Authors: Naidoo, Jarushka, Wang, Xuan, Woo, Kaitlin M., Iyriboz, Tunç, Halpenny, Darragh, Cunningham, Jane, Chaft, Jamie E., Segal, Neil H., Callahan, Margaret K., Lesokhin, Alexander M., Rosenberg, Jonathan E., Voss, Martin H., Rudin, Charles M., Rizvi, Hira, Hou, Xue, Rodríguez, Katherine, Albano, Melanie, Gordon, Ruth-Ann, Leduc, Charles, Rekhtman, Natasha, Harris, Bianca, Menzies, Alexander M., Guminski, Alexander, Carlino, Matteo S., Kong, Benjamin Y., Wolchok, Jedd D., Postow, Michael A., Long, Georgina V., Hellmann, Matthew D.

Year: 2016

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2016.68.2005

Paper LAG-3 and PD-1/PD-L1 inhibitors might become a promising treatment for small cell lung cancer

Yi Xu, Liping Zhang, Shengyu Wu, Wei Zhang, Yu Liu, Bin Chen, Sha Zhao, Wei Li, Chenglong Sun, Hao Wang, Peixin Chen, Chunyan Wu, Yayi He · 2020 · DOI

Full title: LAG-3 and PD-1/PD-L1 inhibitors might become a promising treatment for small cell lung cancer

Authors: Yi Xu, Liping Zhang, Shengyu Wu, Wei Zhang, Yu Liu, Bin Chen, Sha Zhao, Wei Li, Chenglong Sun, Hao Wang, Peixin Chen, Chunyan Wu, Yayi He

Year: 2020

DOI: https://doi.org/10.21203/rs.3.rs-41769/v1

Paper Modulatory effects of gut microbiome in cancer immunotherapy: A novel paradigm for blockade of immune checkpoint inhibitors.

Rezasoltani, Sama, Yadegar, Abbas, Asadzadeh Aghdaei, Hamid, Reza Zali, Mohammad · 2021 · Cancer medicine · DOI

Full title: Modulatory effects of gut microbiome in cancer immunotherapy: A novel paradigm for blockade of immune checkpoint inhibitors.

Authors: Rezasoltani, Sama, Yadegar, Abbas, Asadzadeh Aghdaei, Hamid, Reza Zali, Mohammad

Year: 2021

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.3694

Paper Therapy implications of the role of interleukin-2 in cancer.

Lissoni, Paolo · 2017 · Expert review of clinical immunology · DOI

Full title: Therapy implications of the role of interleukin-2 in cancer.

Authors: Lissoni, Paolo

Year: 2017

Venue: Expert review of clinical immunology

DOI: https://doi.org/10.1080/1744666X.2017.1245146

Paper Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma.

Saha, Dipongkor, Martuza, Robert L, Rabkin, Samuel D · 2018 · Immunotherapy · DOI

Full title: Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma.

Authors: Saha, Dipongkor, Martuza, Robert L, Rabkin, Samuel D

Year: 2018

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2018-0009

Paper Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced nasopharyngeal carcinoma (NPC): Pooled cohort data from phase 1a/1b trials.

Hongyun Zhao, Yan Huang, W. Fang, Yuxiang Ma, Yang Zhang, Xiao-Li Wei, Yanhua Yang, Wei Yang, Furong Liu, Zuan Lin, Jianing Li, Li Zhang · 2022 · Journal of Clinical Oncology · DOI

Full title: Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced nasopharyngeal carcinoma (NPC): Pooled cohort data from phase 1a/1b trials.

Authors: Hongyun Zhao, Yan Huang, W. Fang, Yuxiang Ma, Yang Zhang, Xiao-Li Wei, Yanhua Yang, Wei Yang, Furong Liu, Zuan Lin, Jianing Li, Li Zhang

Year: 2022

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2022.40.16_suppl.6034

Paper Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.

Robin, Tyler P, Breeze, Robert E, Smith, Derek E, Rusthoven, Chad G, Lewis, Karl D, Gonzalez, Rene, Brill, Amanda, Saiki, Robin, Stuhr, Kelly, Gaspar, Laurie E, Karam, Sana D, Raben, David, Kavanagh, Brian D, Nath, Sameer K, Liu, Arthur K · 2018 · Journal of neuro-oncology · DOI

Full title: Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.

Authors: Robin, Tyler P, Breeze, Robert E, Smith, Derek E, Rusthoven, Chad G, Lewis, Karl D, Gonzalez, Rene, Brill, Amanda, Saiki, Robin, Stuhr, Kelly, Gaspar, Laurie E, Karam, Sana D, Raben, David, Kavanagh, Brian D, Nath, Sameer K, Liu, Arthur K

Year: 2018

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-018-2930-5

Paper Salvage nivolumab plus ipilimumab after prior PD-1/PD-L1 inhibitor treatment in metastatic renal cell carcinoma: A meta-analysis.

M. Yin, Sherry Mori-Vogt, M. Hinkley, A. Parikh, Yuanquan Yang, K. Collier, A. Miah, Mingjia Li · 2021 · DOI

Full title: Salvage nivolumab plus ipilimumab after prior PD-1/PD-L1 inhibitor treatment in metastatic renal cell carcinoma: A meta-analysis.

Authors: M. Yin, Sherry Mori-Vogt, M. Hinkley, A. Parikh, Yuanquan Yang, K. Collier, A. Miah, Mingjia Li

Year: 2021

DOI: https://doi.org/10.1200/jco.2021.39.6_suppl.305

Paper Immunotherapy for ovarian cancer: towards a tailored immunophenotype-based approach

Ghisoni, Eleonora, Morotti, Matteo, Sarivalasis, Apostolos, Grimm, Alizée J, Kandalaft, Lana E., Laniti, Denarda Dangaj, Coukos, George · 2024 · Nature Reviews Clinical Oncology · DOI

Full title: Immunotherapy for ovarian cancer: towards a tailored immunophenotype-based approach

Authors: Ghisoni, Eleonora, Morotti, Matteo, Sarivalasis, Apostolos, Grimm, Alizée J, Kandalaft, Lana E., Laniti, Denarda Dangaj, Coukos, George

Year: 2024

Venue: Nature Reviews Clinical Oncology

DOI: https://doi.org/10.1038/s41571-024-00937-4

Paper Combination therapy: Future directions of immunotherapy in small cell lung cancer.

Huang, Wei, Chen, Jia-Jia, Xing, Rui, Zeng, Yue-Can · 2021 · Translational oncology · DOI

Full title: Combination therapy: Future directions of immunotherapy in small cell lung cancer.

Authors: Huang, Wei, Chen, Jia-Jia, Xing, Rui, Zeng, Yue-Can

Year: 2021

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2020.100889

Paper Impact of senescence cell signature in patients with non-small cell carcinoma and melanoma receiving PD-L1/PD-1 inhibitors.

Koh, Young Wha, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo · 2024 · Mechanisms of ageing and development · DOI

Full title: Impact of senescence cell signature in patients with non-small cell carcinoma and melanoma receiving PD-L1/PD-1 inhibitors.

Authors: Koh, Young Wha, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo

Year: 2024

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2024.111999

Paper Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

Nakao, Shinsuke, Arai, Yukinori, Tasaki, Mamoru, Yamashita, Midori, Murakami, Ryuji, Kawase, Tatsuya, Amino, Nobuaki, Nakatake, Motomu, Kurosaki, Hajime, Mori, Masamichi, Takeuchi, Masahiro, Nakamura, Takafumi · 2020 · Science translational medicine · DOI

Full title: Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

Authors: Nakao, Shinsuke, Arai, Yukinori, Tasaki, Mamoru, Yamashita, Midori, Murakami, Ryuji, Kawase, Tatsuya, Amino, Nobuaki, Nakatake, Motomu, Kurosaki, Hajime, Mori, Masamichi, Takeuchi, Masahiro, Nakamura, Takafumi

Year: 2020

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.aax7992

Paper PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors.

Soares, Kevin C, Rucki, Agnieszka A, Wu, Annie A, Olino, Kelly, Xiao, Qian, Chai, Yi, Wamwea, Anthony, Bigelow, Elaine, Lutz, Eric, Liu, Linda, Yao, Sheng, Anders, Robert A, Laheru, Daniel, Wolfgang, Christopher L, Edil, Barish H, Schulick, Richard D, Jaffee, Elizabeth M, Zheng, Lei · 2015 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors.

Authors: Soares, Kevin C, Rucki, Agnieszka A, Wu, Annie A, Olino, Kelly, Xiao, Qian, Chai, Yi, Wamwea, Anthony, Bigelow, Elaine, Lutz, Eric, Liu, Linda, Yao, Sheng, Anders, Robert A, Laheru, Daniel, Wolfgang, Christopher L, Edil, Barish H, Schulick, Richard D, Jaffee, Elizabeth M, Zheng, Lei

Year: 2015

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000062

Paper Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy.

Chen, Jiang, Amoozgar, Zohreh, Liu, Xin, Aoki, Shuichi, Liu, Zelong, Shin, Sarah, Matsui, Aya, Pu, Zhangya, Lei, Pin-Ji, Datta, Meenal, Zhu, Lingling, Ruan, Zhiping, Shi, Lei, Staiculescu, Daniel, Inoue, Koetsu, Munn, Lance L, Fukumura, Dai, Huang, Peigen, Bardeesy, Nabeel, Ho, Won Jin, Jain, Rakesh K, Duda, Dan G · 2023 · bioRxiv : the preprint server for biology · DOI

Full title: Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy.

Authors: Chen, Jiang, Amoozgar, Zohreh, Liu, Xin, Aoki, Shuichi, Liu, Zelong, Shin, Sarah, Matsui, Aya, Pu, Zhangya, Lei, Pin-Ji, Datta, Meenal, Zhu, Lingling, Ruan, Zhiping, Shi, Lei, Staiculescu, Daniel, Inoue, Koetsu, Munn, Lance L, Fukumura, Dai, Huang, Peigen, Bardeesy, Nabeel, Ho, Won Jin, Jain, Rakesh K, Duda, Dan G

Year: 2023

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.01.26.525680

Paper Bispecific anti-PD-1/CTLA-4 antibody for advanced solid tumors.

Perez-Santos, Martin · 2020 · Pharmaceutical patent analyst · DOI

Full title: Bispecific anti-PD-1/CTLA-4 antibody for advanced solid tumors.

Authors: Perez-Santos, Martin

Year: 2020

Venue: Pharmaceutical patent analyst

DOI: https://doi.org/10.4155/ppa-2020-0017

Paper Efficacy and safety of PD-1/PD-L1 plus CTLA-4 antibodies ± other therapies in lung cancer: a systematic review and meta-analysis.

Shen, Xiang, Huang, Shangke, Xiao, Hua, Zeng, Shan, Liu, Jiexing, Ran, Zhuolan, Xiong, Bin · 2023 · European journal of hospital pharmacy : science and practice · DOI

Full title: Efficacy and safety of PD-1/PD-L1 plus CTLA-4 antibodies ± other therapies in lung cancer: a systematic review and meta-analysis.

Authors: Shen, Xiang, Huang, Shangke, Xiao, Hua, Zeng, Shan, Liu, Jiexing, Ran, Zhuolan, Xiong, Bin

Year: 2023

Venue: European journal of hospital pharmacy : science and practice

DOI: https://doi.org/10.1136/ejhpharm-2021-002803

Paper Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade

Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, Zi, Yang, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L. · 2024 · DOI

Full title: Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade

Authors: Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, Zi, Yang, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D., Dunn, Joe Dan, Johnson, Jason M., Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R., Ferrarotto, Renata, Garden, Adam S., Fuller, Clifton D., Reddy, Jay P., Gross, Neil D., Lango, Miriam N., Leung, Cheuk Hong, Liu, Suyu, Liu, Diane, Lee, J. Jack, Curran, Michael A., Phan, Jack, Chen, Ken, Gillison, Maura L.

Year: 2024

DOI: https://doi.org/10.1101/2024.01.04.23300616

Paper Targeted Therapy of Melanoma.

Berking, Carola · 2018 · The journal of investigative dermatology. Symposium proceedings · DOI

Full title: Targeted Therapy of Melanoma.

Authors: Berking, Carola

Year: 2018

Venue: The journal of investigative dermatology. Symposium proceedings

DOI: https://doi.org/10.1016/j.jisp.2018.09.009

Paper PD-1, CTLA-4 Point to Drug Response.

· 2016 · Cancer discovery · DOI

Full title: PD-1, CTLA-4 Point to Drug Response.

Year: 2016

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-NB2016-116

Paper Advanced endometrial cancer-The next generation of treatment: A society of gynecologic oncology journal club clinical commentary.

Tillmanns, Todd, Masri, Amal, Stewart, Chelsea, Chase, Dana, Karnezis, Anthony, Chen, Lee-May, Urban, Renata · 2024 · Gynecologic oncology reports · DOI

Full title: Advanced endometrial cancer-The next generation of treatment: A society of gynecologic oncology journal club clinical commentary.

Authors: Tillmanns, Todd, Masri, Amal, Stewart, Chelsea, Chase, Dana, Karnezis, Anthony, Chen, Lee-May, Urban, Renata

Year: 2024

Venue: Gynecologic oncology reports

DOI: https://doi.org/10.1016/j.gore.2024.101462

Paper From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials Wisely

Day, Daphne, Monjazeb, Arta M., Sharon, Elad, Ivy, S. Percy, Rubin, Eric H., Rosner, Gary L., Butler, Marcus O. · 2017 · Clinical Cancer Research · DOI

Full title: From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials Wisely

Authors: Day, Daphne, Monjazeb, Arta M., Sharon, Elad, Ivy, S. Percy, Rubin, Eric H., Rosner, Gary L., Butler, Marcus O.

Year: 2017

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-16-3064

Paper Neoadjuvant immunotherapy in breast cancer: a paradigm shift?

E. Fountzila, M. Ignatiadis · 2020 · ecancermedicalscience · DOI

Full title: Neoadjuvant immunotherapy in breast cancer: a paradigm shift?

Authors: E. Fountzila, M. Ignatiadis

Year: 2020

Venue: ecancermedicalscience

DOI: https://doi.org/10.3332/ecancer.2020.1147

Paper Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.

Schramme, Florence, Crosignani, Stefano, Frederix, Kim, Hoffmann, Delia, Pilotte, Luc, Stroobant, Vincent, Preillon, Julie, Driessens, Gregory, Van den Eynde, Benoit J · 2020 · Cancer immunology research · DOI

Full title: Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.

Authors: Schramme, Florence, Crosignani, Stefano, Frederix, Kim, Hoffmann, Delia, Pilotte, Luc, Stroobant, Vincent, Preillon, Julie, Driessens, Gregory, Van den Eynde, Benoit J

Year: 2020

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-19-0041

Paper PD-1/PD-L1 checkpoint blockades in non-small cell lung cancer: New development and challenges.

Meng, Xiangjiao, Liu, Yanli, Zhang, Jianjun, Teng, Feifei, Xing, Ligang, Yu, Jinming · 2017 · Cancer letters · DOI

Full title: PD-1/PD-L1 checkpoint blockades in non-small cell lung cancer: New development and challenges.

Authors: Meng, Xiangjiao, Liu, Yanli, Zhang, Jianjun, Teng, Feifei, Xing, Ligang, Yu, Jinming

Year: 2017

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2017.06.033

Paper Immune Checkpoint Inhibition in Hepatocellular Carcinoma: Basics and Ongoing Clinical Trials.

Kudo, Masatoshi · 2017 · Oncology · DOI

Full title: Immune Checkpoint Inhibition in Hepatocellular Carcinoma: Basics and Ongoing Clinical Trials.

Authors: Kudo, Masatoshi

Year: 2017

Venue: Oncology

DOI: https://doi.org/10.1159/000451016

Paper Fc Effector Function of Immune Checkpoint Blocking Antibodies in Oncology.

Martineau, Romane, Susini, Sandrine, Marabelle, Aurelien · 2024 · Immunological reviews · DOI

Full title: Fc Effector Function of Immune Checkpoint Blocking Antibodies in Oncology.

Authors: Martineau, Romane, Susini, Sandrine, Marabelle, Aurelien

Year: 2024

Venue: Immunological reviews

DOI: https://doi.org/10.1111/imr.13427

Paper Clinical and economic outcomes associated with treatment sequences in patients with BRAF-mutant advanced melanoma.

Tarhini, Ahmad, McDermott, David, Ambavane, Apoorva, Gupte-Singh, Komal, Aponte-Ribero, Valerie, Ritchings, Corey, Benedict, Agnes, Rao, Sumati, Regan, Meredith M, Atkins, Michael · 2019 · Immunotherapy · DOI

Full title: Clinical and economic outcomes associated with treatment sequences in patients with BRAF-mutant advanced melanoma.

Authors: Tarhini, Ahmad, McDermott, David, Ambavane, Apoorva, Gupte-Singh, Komal, Aponte-Ribero, Valerie, Ritchings, Corey, Benedict, Agnes, Rao, Sumati, Regan, Meredith M, Atkins, Michael

Year: 2019

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2018-0168

Paper The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.

Xu, Zhehao, Wang, Yue, Jiang, Changcheng, Wang, Zhengwei, Cheng, YongFeng, Fan, Manli · 2024 · Molecular pain · DOI

Full title: The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.

Authors: Xu, Zhehao, Wang, Yue, Jiang, Changcheng, Wang, Zhengwei, Cheng, YongFeng, Fan, Manli

Year: 2024

Venue: Molecular pain

DOI: https://doi.org/10.1177/17448069241252384

Paper Real-world evaluation of the effectiveness and predictive factors of anti-PD-1/PD-L1 inhibitors as the first-line therapy for metastatic non-small cell lung cancer.

Chen, Jing, Yang, Dingyi, Lei, Qianqian, Long, Yanyan · 2023 · Asian journal of surgery · DOI

Full title: Real-world evaluation of the effectiveness and predictive factors of anti-PD-1/PD-L1 inhibitors as the first-line therapy for metastatic non-small cell lung cancer.

Authors: Chen, Jing, Yang, Dingyi, Lei, Qianqian, Long, Yanyan

Year: 2023

Venue: Asian journal of surgery

DOI: https://doi.org/10.1016/j.asjsur.2023.04.080

Paper Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: “A sharp sword”

Liang, Ping, Ye, Xin, Li, Xin · 2019 · Journal of Cancer Research and Therapeutics · DOI

Full title: Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: “A sharp sword”

Authors: Liang, Ping, Ye, Xin, Li, Xin

Year: 2019

Venue: Journal of Cancer Research and Therapeutics

DOI: https://doi.org/10.4103/jcrt.jcrt_910_18

Paper Association between immune-related adverse events (irAEs) and clinical outcomes (CO) in advanced urothelial cancer patients (pts) treated with immunotherapy (IO).

J. Shabto, D. Martini, Yuan Liu, D. Ravindranathan, Meredith R. Kline, E. Hitron, G. Russler, S. Caulfield, H. Kissick, M. Alemozaffar, K. Ogan, W. Harris, V. Master, B. Carthon, O. Kucuk, M. Bilen · 2019 · Journal of Clinical Oncology · DOI

Full title: Association between immune-related adverse events (irAEs) and clinical outcomes (CO) in advanced urothelial cancer patients (pts) treated with immunotherapy (IO).

Authors: J. Shabto, D. Martini, Yuan Liu, D. Ravindranathan, Meredith R. Kline, E. Hitron, G. Russler, S. Caulfield, H. Kissick, M. Alemozaffar, K. Ogan, W. Harris, V. Master, B. Carthon, O. Kucuk, M. Bilen

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.7_suppl.472

Paper Challenges faced when identifying patients for combination immunotherapy.

M. Ernstoff, S. Gandhi, M. Pandey, I. Puzanov, P. Grivas, A. Montero, V. Velcheti, M. Turk, C. Diaz-Montero, L. Lewis, C. Morrison · 2017 · Future Oncology · DOI

Full title: Challenges faced when identifying patients for combination immunotherapy.

Authors: M. Ernstoff, S. Gandhi, M. Pandey, I. Puzanov, P. Grivas, A. Montero, V. Velcheti, M. Turk, C. Diaz-Montero, L. Lewis, C. Morrison

Year: 2017

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2017-0218

Paper Hemorrhage profile associated with immune checkpoint inhibitors: a systematic review and a real-world study based on the FAERS database.

Chen, Mengting, He, Zhichao, Zhu, Jianhong, Yang, Shan, Gao, Siyuan, Wu, Jie, Ren, Huaying, Liang, Dan, Jiang, Wei, Zou, Ying, Yu, Xiaoxia, Wu, Junyan · 2024 · Expert opinion on drug safety · DOI

Full title: Hemorrhage profile associated with immune checkpoint inhibitors: a systematic review and a real-world study based on the FAERS database.

Authors: Chen, Mengting, He, Zhichao, Zhu, Jianhong, Yang, Shan, Gao, Siyuan, Wu, Jie, Ren, Huaying, Liang, Dan, Jiang, Wei, Zou, Ying, Yu, Xiaoxia, Wu, Junyan

Year: 2024

Venue: Expert opinion on drug safety

DOI: https://doi.org/10.1080/14740338.2024.2327504

Paper First-in-human phase I open-label study of the anti–TIM-3 monoclonal antibody INCAGN02390 in patients with select advanced or metastatic solid tumors

Martin Gutierrez, Shou-Ching Tang, J. Powderly, A. Balmanoukian, Paul E Hoyle, Zhiwan Dong, Lulu Cheng, Xiaohua Gong, John E Janik, N. Bourayou, Omid Hamid · 2025 · The Oncologist · DOI

Full title: First-in-human phase I open-label study of the anti–TIM-3 monoclonal antibody INCAGN02390 in patients with select advanced or metastatic solid tumors

Authors: Martin Gutierrez, Shou-Ching Tang, J. Powderly, A. Balmanoukian, Paul E Hoyle, Zhiwan Dong, Lulu Cheng, Xiaohua Gong, John E Janik, N. Bourayou, Omid Hamid

Year: 2025

Venue: The Oncologist

DOI: https://doi.org/10.1093/oncolo/oyaf144

Paper Adjuvant systemic therapy in high-risk melanoma.

Blankenstein, Stephanie A, van Akkooi, Alexander C J · 2019 · Melanoma research · DOI

Full title: Adjuvant systemic therapy in high-risk melanoma.

Authors: Blankenstein, Stephanie A, van Akkooi, Alexander C J

Year: 2019

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000604

Paper Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1.

Mazor, Ronit, King, Emily, Pastan, Ira · 2018 · Cellular immunology · DOI

Full title: Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1.

Authors: Mazor, Ronit, King, Emily, Pastan, Ira

Year: 2018

Venue: Cellular immunology

DOI: https://doi.org/10.1016/j.cellimm.2018.08.016

Paper Combination immunotherapy in metastatic renal cell carcinoma. Are we leaving something back?

Di Nunno, Vincenzo, Gatto, Lidia, Fragomeno, Benedetta, Cubelli, Marta, Nobili, Elisabetta, Romano, Ida, Santoni, Matteo, Pisconti, Salvatore, Montironi, Rodolfo, Massari, Francesco · 2018 · Future oncology (London, England) · DOI

Full title: Combination immunotherapy in metastatic renal cell carcinoma. Are we leaving something back?

Authors: Di Nunno, Vincenzo, Gatto, Lidia, Fragomeno, Benedetta, Cubelli, Marta, Nobili, Elisabetta, Romano, Ida, Santoni, Matteo, Pisconti, Salvatore, Montironi, Rodolfo, Massari, Francesco

Year: 2018

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2018-0604

Paper Combination Immunotherapy for Hepatocellular Carcinoma: Where Are We Currently?

Uson Junior, Pedro Luiz Serrano, Nagalo, Bolni Marius, Ahn, Daniel H, Bekaii-Saab, Tanios, Borad, Mitesh J · 2021 · Seminars in liver disease · DOI

Full title: Combination Immunotherapy for Hepatocellular Carcinoma: Where Are We Currently?

Authors: Uson Junior, Pedro Luiz Serrano, Nagalo, Bolni Marius, Ahn, Daniel H, Bekaii-Saab, Tanios, Borad, Mitesh J

Year: 2021

Venue: Seminars in liver disease

DOI: https://doi.org/10.1055/s-0040-1722646

Paper Nonsurgical Management of Melanoma Brain Metastasis: Current Therapeutics, Challenges, and Strategies for Progress

Makawita, Shalini, Tawbi, Hussein A. · 2021 · American Society of Clinical Oncology Educational Book · DOI

Full title: Nonsurgical Management of Melanoma Brain Metastasis: Current Therapeutics, Challenges, and Strategies for Progress

Authors: Makawita, Shalini, Tawbi, Hussein A.

Year: 2021

Venue: American Society of Clinical Oncology Educational Book

DOI: https://doi.org/10.1200/edbk_321137

Paper Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Larkin, James, Chiarion‐Sileni, Vanna, González, René, Grob, Jean‐Jacques, Rutkowski, Piotr, Lao, Christopher D., Cowey, C. Lance, Schadendorf, Dirk, Wagstaff, John, Dummer, Reinhard, Ferrucci, Pier Francesco, Smylie, Michael, Hogg, David, Hill, Andrew F., Márquez‐Rodas, Iván, Haanen, John B.A.G., Guidoboni, Massimo, Maio, Michele, Schöffski, Patrick, Carlino, Matteo S., Lebbé, Célèste, McArthur, Grant A., Ascierto, Paolo A., Daniels, Gregory A., Long, Georgina V., Bastholt, Lars, Rizzo, Jasmine I., Balogh, Ágnes, Moshyk, Andriy, Hodi, F. Stephen, Wolchok, Jedd D. · 2019 · New England Journal of Medicine · DOI

Full title: Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Authors: Larkin, James, Chiarion‐Sileni, Vanna, González, René, Grob, Jean‐Jacques, Rutkowski, Piotr, Lao, Christopher D., Cowey, C. Lance, Schadendorf, Dirk, Wagstaff, John, Dummer, Reinhard, Ferrucci, Pier Francesco, Smylie, Michael, Hogg, David, Hill, Andrew F., Márquez‐Rodas, Iván, Haanen, John B.A.G., Guidoboni, Massimo, Maio, Michele, Schöffski, Patrick, Carlino, Matteo S., Lebbé, Célèste, McArthur, Grant A., Ascierto, Paolo A., Daniels, Gregory A., Long, Georgina V., Bastholt, Lars, Rizzo, Jasmine I., Balogh, Ágnes, Moshyk, Andriy, Hodi, F. Stephen, Wolchok, Jedd D.

Year: 2019

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1910836

Paper Targets for improving tumor response to radiotherapy.

Mortezaee, Keywan, Parwaie, Wrya, Motevaseli, Elahe, Mirtavoos-Mahyari, Hanifeh, Musa, Ahmed Eleojo, Shabeeb, Dheyauldeen, Esmaely, Farid, Najafi, Masoud, Farhood, Bagher · 2019 · International immunopharmacology · DOI

Full title: Targets for improving tumor response to radiotherapy.

Authors: Mortezaee, Keywan, Parwaie, Wrya, Motevaseli, Elahe, Mirtavoos-Mahyari, Hanifeh, Musa, Ahmed Eleojo, Shabeeb, Dheyauldeen, Esmaely, Farid, Najafi, Masoud, Farhood, Bagher

Year: 2019

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2019.105847

Paper Atezolizumab for the treatment of non-small cell lung cancer

Santini, Fernando C., Rudin, Charles M. · 2017 · Expert Review of Clinical Pharmacology · DOI

Full title: Atezolizumab for the treatment of non-small cell lung cancer

Authors: Santini, Fernando C., Rudin, Charles M.

Year: 2017

Venue: Expert Review of Clinical Pharmacology

DOI: https://doi.org/10.1080/17512433.2017.1356717

Paper Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma.

Danno, Tetsuya, Iwata, Shohei, Niimi, Fusako, Honda, Sachi, Okada, Haruka, Azuma, Takeshi · 2021 · Case reports in urology · DOI

Full title: Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma.

Authors: Danno, Tetsuya, Iwata, Shohei, Niimi, Fusako, Honda, Sachi, Okada, Haruka, Azuma, Takeshi

Year: 2021

Venue: Case reports in urology

DOI: https://doi.org/10.1155/2021/9936330

Paper An overview of up-and-coming immune checkpoint inhibitors for pancreatic cancer.

Mahadevia, Himil, Uson Junior, Pedro Luiz Serrano, Wang, Jing, Borad, Mitesh, Babiker, Hani · 2024 · Expert opinion on pharmacotherapy · DOI

Full title: An overview of up-and-coming immune checkpoint inhibitors for pancreatic cancer.

Authors: Mahadevia, Himil, Uson Junior, Pedro Luiz Serrano, Wang, Jing, Borad, Mitesh, Babiker, Hani

Year: 2024

Venue: Expert opinion on pharmacotherapy

DOI: https://doi.org/10.1080/14656566.2024.2304125

Paper Thyroid storm induced by combined nivolumab and ipilimumab immunotherapy in advanced non-small cell lung cancer

Kataoka, Shunichi, Matsuno, Kei, Suga, Tadatomo, Takahashi, Kazuhisa · 2022 · BMJ Case Reports · DOI

Full title: Thyroid storm induced by combined nivolumab and ipilimumab immunotherapy in advanced non-small cell lung cancer

Authors: Kataoka, Shunichi, Matsuno, Kei, Suga, Tadatomo, Takahashi, Kazuhisa

Year: 2022

Venue: BMJ Case Reports

DOI: https://doi.org/10.1136/bcr-2022-250696

Paper Current and Emerging Perspectives on Immunotherapy for Melanoma.

Daud, Adil · 2015 · Seminars in oncology · DOI

Full title: Current and Emerging Perspectives on Immunotherapy for Melanoma.

Authors: Daud, Adil

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.10.003

Paper Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer.

Ahdoot, Michael, Theodorescu, Dan · 2021 · Expert review of clinical pharmacology · DOI

Full title: Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer.

Authors: Ahdoot, Michael, Theodorescu, Dan

Year: 2021

Venue: Expert review of clinical pharmacology

DOI: https://doi.org/10.1080/17512433.2021.1950531

Paper Immune checkpoints and cancer development: Therapeutic implications and future directions.

Mehdizadeh, Saber, Bayatipoor, Hashem, Pashangzadeh, Salar, Jafarpour, Roghayeh, Shojaei, Zeinab, Motallebnezhad, Morteza · 2021 · Pathology, research and practice · DOI

Full title: Immune checkpoints and cancer development: Therapeutic implications and future directions.

Authors: Mehdizadeh, Saber, Bayatipoor, Hashem, Pashangzadeh, Salar, Jafarpour, Roghayeh, Shojaei, Zeinab, Motallebnezhad, Morteza

Year: 2021

Venue: Pathology, research and practice

DOI: https://doi.org/10.1016/j.prp.2021.153485

Paper A COMPREHENSIVE REVIEW OF NIVOLUMAB AND IPILIMUMAB COMBINATION THERAPY IN ADVANCED MELANOMA

Subashini, R., Bi, A. Mubina, Roshika, S., Harini, V., Jayasri, S., Sri, S. Pooja · 2026 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: A COMPREHENSIVE REVIEW OF NIVOLUMAB AND IPILIMUMAB COMBINATION THERAPY IN ADVANCED MELANOMA

Authors: Subashini, R., Bi, A. Mubina, Roshika, S., Harini, V., Jayasri, S., Sri, S. Pooja

Year: 2026

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.18790278

Paper CD40 agonism improves anti-tumor T cell priming induced by the combination of radiation therapy plus CTLA4 inhibition and enhances tumor response.

Charpentier, Maud, Formenti, Silvia, Demaria, Sandra · 2023 · Oncoimmunology · DOI

Full title: CD40 agonism improves anti-tumor T cell priming induced by the combination of radiation therapy plus CTLA4 inhibition and enhances tumor response.

Authors: Charpentier, Maud, Formenti, Silvia, Demaria, Sandra

Year: 2023

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2023.2258011

Paper PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltration.

Su, Shengchen, You, Sungyong, Wang, Yanping, Tamukong, Patrick, Quist, Michael J, Grasso, Catherine S, Kim, Hyung L · 2023 · Cancer letters · DOI

Full title: PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltration.

Authors: Su, Shengchen, You, Sungyong, Wang, Yanping, Tamukong, Patrick, Quist, Michael J, Grasso, Catherine S, Kim, Hyung L

Year: 2023

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2022.216034

Paper Combination therapy for mCRPC with immune checkpoint inhibitors, ADT and vaccine: A mathematical model.

Siewe, Nourridine, Friedman, Avner · 2022 · PloS one · DOI

Full title: Combination therapy for mCRPC with immune checkpoint inhibitors, ADT and vaccine: A mathematical model.

Authors: Siewe, Nourridine, Friedman, Avner

Year: 2022

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0262453

Paper Immune checkpoint blockade as a novel immunotherapeutic strategy for renal cell carcinoma: a review of clinical trials.

Godwin, J Luke, Zibelman, Matthew, Plimack, Elizabeth R, Geynisman, Daniel M · 2014 · Discovery medicine

Full title: Immune checkpoint blockade as a novel immunotherapeutic strategy for renal cell carcinoma: a review of clinical trials.

Authors: Godwin, J Luke, Zibelman, Matthew, Plimack, Elizabeth R, Geynisman, Daniel M

Year: 2014

Venue: Discovery medicine

Paper AHCC®, a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkpoint Blockade Effect in Murine Colon Cancer.

Park, Hong-Jai, Boo, Sunjin, Park, Inkeun, Shin, Min Sun, Takahashi, Tsukasa, Takanari, Jun, Homma, Kohei, Kang, Insoo · 2022 · Frontiers in immunology · DOI

Full title: AHCC®, a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkpoint Blockade Effect in Murine Colon Cancer.

Authors: Park, Hong-Jai, Boo, Sunjin, Park, Inkeun, Shin, Min Sun, Takahashi, Tsukasa, Takanari, Jun, Homma, Kohei, Kang, Insoo

Year: 2022

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2022.875872

Paper Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial.

Klein, Oliver, Kee, Damien, Gao, Bo, Markman, Ben, da Gama Duarte, Jessica, Quigley, Luke, Jackett, Louise, Linklater, Richelle, Strickland, Andrew, Scott, Clare, Mileshkin, Linda, Palmer, Jodie, Carlino, Matteo, Behren, Andreas, Cebon, Jonathan · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial.

Authors: Klein, Oliver, Kee, Damien, Gao, Bo, Markman, Ben, da Gama Duarte, Jessica, Quigley, Luke, Jackett, Louise, Linklater, Richelle, Strickland, Andrew, Scott, Clare, Mileshkin, Linda, Palmer, Jodie, Carlino, Matteo, Behren, Andreas, Cebon, Jonathan

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2021-003156

Paper Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue.

Varricchi, Gilda, Marone, Giancarlo, Mercurio, Valentina, Galdiero, Maria Rosaria, Bonaduce, Domenico, Tocchetti, Carlo G · 2018 · Current medicinal chemistry · DOI

Full title: Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue.

Authors: Varricchi, Gilda, Marone, Giancarlo, Mercurio, Valentina, Galdiero, Maria Rosaria, Bonaduce, Domenico, Tocchetti, Carlo G

Year: 2018

Venue: Current medicinal chemistry

DOI: https://doi.org/10.2174/0929867324666170407125017

Paper Tumor-Naïve Circulating Tumor DNA as an Early Response Biomarker for Patients Treated With Immunotherapy in Early Phase Clinical Trials

E. Sanz-García, S. Genta, Xiaoxi Chen, Q. Ou, D. Araujo, A. A. Abdul Razak, A. Hansen, A. Spreafico, H. Bao, Xue Wu, L. Siu, P. Bedard · 2023 · JCO Precision Oncology · DOI

Full title: Tumor-Naïve Circulating Tumor DNA as an Early Response Biomarker for Patients Treated With Immunotherapy in Early Phase Clinical Trials

Authors: E. Sanz-García, S. Genta, Xiaoxi Chen, Q. Ou, D. Araujo, A. A. Abdul Razak, A. Hansen, A. Spreafico, H. Bao, Xue Wu, L. Siu, P. Bedard

Year: 2023

Venue: JCO Precision Oncology

DOI: https://doi.org/10.1200/po.22.00509

Paper PP223 Single-cell RNA sequencing in metastatic lung cancer uncovers the efficacy of PD-1/PD-L1 inhibitors on immune cell population

H. Choi, Kyung-Ho Pyo, S.M. Lim, B. Cho, S. Hong · 2022 · ESMO Open · DOI

Full title: PP223 Single-cell RNA sequencing in metastatic lung cancer uncovers the efficacy of PD-1/PD-L1 inhibitors on immune cell population

Authors: H. Choi, Kyung-Ho Pyo, S.M. Lim, B. Cho, S. Hong

Year: 2022

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2022.100719

Paper In Situ Vaccination after Accelerated Hypofractionated Radiation and Surgery in a Mesothelioma Mouse Model.

De La Maza, Luis, Wu, Matthew, Wu, Licun, Yun, Hana, Zhao, Yidan, Cattral, Mark, McCart, Andrea, Cho, Bc John, de Perrot, Marc · 2017 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: In Situ Vaccination after Accelerated Hypofractionated Radiation and Surgery in a Mesothelioma Mouse Model.

Authors: De La Maza, Luis, Wu, Matthew, Wu, Licun, Yun, Hana, Zhao, Yidan, Cattral, Mark, McCart, Andrea, Cho, Bc John, de Perrot, Marc

Year: 2017

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0438

Paper Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunotherapy relapsed melanoma with detected homologous recombination deficiency.

Khaddour, Karam, Ansstas, Michael, Ansstas, George · 2021 · Cold Spring Harbor molecular case studies · DOI

Full title: Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunotherapy relapsed melanoma with detected homologous recombination deficiency.

Authors: Khaddour, Karam, Ansstas, Michael, Ansstas, George

Year: 2021

Venue: Cold Spring Harbor molecular case studies

DOI: https://doi.org/10.1101/mcs.a006129

Paper A Multiaxial Systematic Review On Contemporary Oncotherapeutic Armamentarium And Lobectomy‑Centric Surgical Stratagems In Lung Carcinomas: Histopathological‑Radiological Correlatives, Molecularly Targeted Regimens, And Immunomodulatory Paradigm Shifts In

Dr. Avijit Roy Mondal, Dr. Suhena Sarkar, DrSayani Mondal, Dr Birupaksha Biswas · 2025 · International Journal of Environmental Science · DOI

Full title: A Multiaxial Systematic Review On Contemporary Oncotherapeutic Armamentarium And Lobectomy‑Centric Surgical Stratagems In Lung Carcinomas: Histopathological‑Radiological Correlatives, Molecularly Targeted Regimens, And Immunomodulatory Paradigm Shifts In

Authors: Dr. Avijit Roy Mondal, Dr. Suhena Sarkar, DrSayani Mondal, Dr Birupaksha Biswas

Year: 2025

Venue: International Journal of Environmental Science

DOI: https://doi.org/10.64252/b0m66375

Paper Characterizing immune checkpoint inhibitor-related cutaneous adverse reactions: A comprehensive analysis of FDA adverse event reporting system (FAERS) database.

Esen, Buğra Han, Özbek, Laşin, Oğuz, Sinem, Selçukbiricik, Fatih · 2024 · Heliyon · DOI

Full title: Characterizing immune checkpoint inhibitor-related cutaneous adverse reactions: A comprehensive analysis of FDA adverse event reporting system (FAERS) database.

Authors: Esen, Buğra Han, Özbek, Laşin, Oğuz, Sinem, Selçukbiricik, Fatih

Year: 2024

Venue: Heliyon

DOI: https://doi.org/10.1016/j.heliyon.2024.e33765

Paper Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

Krijgsman, Oscar, Kemper, Kristel, Boshuizen, Julia, Vredevoogd, David W, Rozeman, Elisa A, Ibanez Molero, Sofia, de Bruijn, Beaunelle, Cornelissen-Steijger, Paulien, Shahrabi, Aida, Del Castillo Velasco-Herrera, Martin, Song, Ji-Ying, Ligtenberg, Maarten A, Kluin, Roelof J C, Kuilman, Thomas, Ross-Macdonald, Petra, Haanen, John B A G, Adams, David J, Blank, Christian U, Peeper, Daniel S · 2021 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

Authors: Krijgsman, Oscar, Kemper, Kristel, Boshuizen, Julia, Vredevoogd, David W, Rozeman, Elisa A, Ibanez Molero, Sofia, de Bruijn, Beaunelle, Cornelissen-Steijger, Paulien, Shahrabi, Aida, Del Castillo Velasco-Herrera, Martin, Song, Ji-Ying, Ligtenberg, Maarten A, Kluin, Roelof J C, Kuilman, Thomas, Ross-Macdonald, Petra, Haanen, John B A G, Adams, David J, Blank, Christian U, Peeper, Daniel S

Year: 2021

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-4218

Paper Treatment Patterns and Attrition With Lines of Therapy for Advanced Urothelial Carcinoma in the US.

Mathew Thomas, Vinay, Jo, Yeonjung, Tripathi, Nishita, Roy, Soumyajit, Chigarira, Beverly, Narang, Arshit, Gebrael, Georges, Hage Chehade, Chadi, Sayegh, Nicolas, Galarza Fortuna, Gliceida, Ji, Richard, Campbell, Patrick, Li, Haoran, Agarwal, Neeraj, Gupta, Sumati, Swami, Umang · 2024 · JAMA network open · DOI

Full title: Treatment Patterns and Attrition With Lines of Therapy for Advanced Urothelial Carcinoma in the US.

Authors: Mathew Thomas, Vinay, Jo, Yeonjung, Tripathi, Nishita, Roy, Soumyajit, Chigarira, Beverly, Narang, Arshit, Gebrael, Georges, Hage Chehade, Chadi, Sayegh, Nicolas, Galarza Fortuna, Gliceida, Ji, Richard, Campbell, Patrick, Li, Haoran, Agarwal, Neeraj, Gupta, Sumati, Swami, Umang

Year: 2024

Venue: JAMA network open

DOI: https://doi.org/10.1001/jamanetworkopen.2024.9417

Paper MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer

Janjigian, Yelena Y., Cutsem, Eric Van, Muro, Kei, Wainberg, Zev A., Al‐Batran, Salah‐Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H., Negro, Alejandra, Tabernero, Josep · 2022 · Future Oncology · DOI

Full title: MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer

Authors: Janjigian, Yelena Y., Cutsem, Eric Van, Muro, Kei, Wainberg, Zev A., Al‐Batran, Salah‐Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H., Negro, Alejandra, Tabernero, Josep

Year: 2022

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2022-0093

Paper Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma.

Fang, Penny, Jiang, Wen, Allen, Pamela, Glitza, Isabella, Guha, Nandita, Hwu, Patrick, Ghia, Amol, Phan, Jack, Mahajan, Anita, Tawbi, Hussein, Li, Jing · 2017 · Journal of neuro-oncology · DOI

Full title: Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma.

Authors: Fang, Penny, Jiang, Wen, Allen, Pamela, Glitza, Isabella, Guha, Nandita, Hwu, Patrick, Ghia, Amol, Phan, Jack, Mahajan, Anita, Tawbi, Hussein, Li, Jing

Year: 2017

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-017-2470-4

Paper Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4.

Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia · 2019 · Molecular cancer · DOI

Full title: Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4.

Authors: Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia

Year: 2019

Venue: Molecular cancer

DOI: https://doi.org/10.1186/s12943-019-1091-2

Paper Dual targeting of TIGIT and VISTA in non-small-cell lung cancer immunotherapy.

Aljabali, Alaa A A, Gammoh, Omar, Qnais, Esam, Alqudah, Abdelrahim, Mishra, Vijay, Mishra, Yachana, El-Tanani, Mohamed · 2025 · EXCLI journal · DOI

Full title: Dual targeting of TIGIT and VISTA in non-small-cell lung cancer immunotherapy.

Authors: Aljabali, Alaa A A, Gammoh, Omar, Qnais, Esam, Alqudah, Abdelrahim, Mishra, Vijay, Mishra, Yachana, El-Tanani, Mohamed

Year: 2025

Venue: EXCLI journal

DOI: https://doi.org/10.17179/excli2025-8735

Paper Hepatocellular Carcinoma: Current Therapeutic Algorithm for Localized and Advanced Disease

Jose, Anju, Bavetta, Maria Grazia, Martinelli, Erika, Bronte, F., Giunta, Emilio Francesco, Manu, Kanjoormana Aryan · 2022 · Journal of Oncology · DOI

Full title: Hepatocellular Carcinoma: Current Therapeutic Algorithm for Localized and Advanced Disease

Authors: Jose, Anju, Bavetta, Maria Grazia, Martinelli, Erika, Bronte, F., Giunta, Emilio Francesco, Manu, Kanjoormana Aryan

Year: 2022

Venue: Journal of Oncology

DOI: https://doi.org/10.1155/2022/3817724

Paper Correlation between circulating cell-free RNA biomarkers and response during combination immunotherapy in previously refractory metastatic TNBC patients.

Garner, Chad, Seery, Tara Elisabeth, Nangia, Chaitali, Lee, John H., Huang, Liyang, Sender, Leonard S., Rabizadeh, Shahrooz, Soon‐Shiong, Patrick · 2019 · Journal of Clinical Oncology · DOI

Full title: Correlation between circulating cell-free RNA biomarkers and response during combination immunotherapy in previously refractory metastatic TNBC patients.

Authors: Garner, Chad, Seery, Tara Elisabeth, Nangia, Chaitali, Lee, John H., Huang, Liyang, Sender, Leonard S., Rabizadeh, Shahrooz, Soon‐Shiong, Patrick

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.e14027

Paper Topological heterogeneity of genomic and immunologic effects from combination immunotherapy treatment in the neoadjuvant setting for renal cell carcinoma (RCC).

Tyler Alban, Salendra Singh, P. Pavicic, P. Rayman, Prerana Parthasarathy Bangalore, Amit Rupani, Vladimir Makarov, C. Przybycin, J. Ko, Venkatesh Krishnamurthi, S. Campbell, T. Chan, B. Rini, C. Diaz-Montero, M. Ornstein · 2024 · Journal of Clinical Oncology · DOI

Full title: Topological heterogeneity of genomic and immunologic effects from combination immunotherapy treatment in the neoadjuvant setting for renal cell carcinoma (RCC).

Authors: Tyler Alban, Salendra Singh, P. Pavicic, P. Rayman, Prerana Parthasarathy Bangalore, Amit Rupani, Vladimir Makarov, C. Przybycin, J. Ko, Venkatesh Krishnamurthi, S. Campbell, T. Chan, B. Rini, C. Diaz-Montero, M. Ornstein

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.4_suppl.454

Paper Response to combined ipilimumab and nivolumab after development of a nephrotic syndrome related to PD-1 monotherapy

V. Glutsch, Franziska Grän, J. Weber, A. Gesierich, M. Goebeler, B. Schilling · 2019 · Journal of Immunotherapy for Cancer · DOI

Full title: Response to combined ipilimumab and nivolumab after development of a nephrotic syndrome related to PD-1 monotherapy

Authors: V. Glutsch, Franziska Grän, J. Weber, A. Gesierich, M. Goebeler, B. Schilling

Year: 2019

Venue: Journal of Immunotherapy for Cancer

DOI: https://doi.org/10.1186/s40425-019-0655-4

Paper Global assessment of hepatic safety in novel immunotherapies: a systematic review and meta-analysis.

Ye, Minyan, Dong, Yinuo, Li, Xiaoyun, Zhi, Yang, Lu, Yuping, Tang, Jieting, Zhong, Wei, Lei, Xiaohong, Mao, Yimin, Huang, Sha, Song, Yanyan · 2025 · Frontiers in immunology · DOI

Full title: Global assessment of hepatic safety in novel immunotherapies: a systematic review and meta-analysis.

Authors: Ye, Minyan, Dong, Yinuo, Li, Xiaoyun, Zhi, Yang, Lu, Yuping, Tang, Jieting, Zhong, Wei, Lei, Xiaohong, Mao, Yimin, Huang, Sha, Song, Yanyan

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1677998

Paper Immunotherapy-induced colitis in metastatic colorectal cancer: a systematic review and meta-analysis.

Saowapa, Sakditad, Polpichai, Natchaya, Siladech, Pharit, Wannaphut, Chalothorn, Tanariyakul, Manasawee, Wattanachayakul, Phuuwadith, Bernal, Diego Olavarria, Garcia Pleitez, Hector, Tijani, Lukman · 2024 · Proceedings (Baylor University. Medical Center) · DOI

Full title: Immunotherapy-induced colitis in metastatic colorectal cancer: a systematic review and meta-analysis.

Authors: Saowapa, Sakditad, Polpichai, Natchaya, Siladech, Pharit, Wannaphut, Chalothorn, Tanariyakul, Manasawee, Wattanachayakul, Phuuwadith, Bernal, Diego Olavarria, Garcia Pleitez, Hector, Tijani, Lukman

Year: 2024

Venue: Proceedings (Baylor University. Medical Center)

DOI: https://doi.org/10.1080/08998280.2024.2342723

Paper Efficacy and safety of lenvatinib combined with PD‑1/PD‑L1 inhibitors in the treatment of hepatocellular carcinoma: A meta‑analysis and systematic review.

Zhang, Baoyan, Su, Linfeng, Lin, Yonghua · 2024 · Oncology letters · DOI

Full title: Efficacy and safety of lenvatinib combined with PD‑1/PD‑L1 inhibitors in the treatment of hepatocellular carcinoma: A meta‑analysis and systematic review.

Authors: Zhang, Baoyan, Su, Linfeng, Lin, Yonghua

Year: 2024

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2024.14445

Paper Abstract CT078: Tumor mutational burden (TMB) as a biomarker for clinical benefit from dual immune checkpoint blockade with nivolumab (nivo) + ipilimumab (ipi) in first-line (1L) non-small cell lung cancer (NSCLC): identification of TMB cutoff from CheckMate 568

Ramalingam, Suresh S., Hellmann, Matthew D., Awad, Mark M., Borghaei, Hossein, Gainor, Justin F., Brahmer, Julie R., Spigel, David R., Reck, Martin, O’Byrne, Kenneth J., Paz‐Ares, Luis, Zerba, Kim E., Li, Xuemei, Geese, William J., Green, George, Lestini, Brian, Szustakowski, Joseph D., Chang, Han, Ready, Neal · 2018 · Cancer Research · DOI

Full title: Abstract CT078: Tumor mutational burden (TMB) as a biomarker for clinical benefit from dual immune checkpoint blockade with nivolumab (nivo) + ipilimumab (ipi) in first-line (1L) non-small cell lung cancer (NSCLC): identification of TMB cutoff from CheckMate 568

Authors: Ramalingam, Suresh S., Hellmann, Matthew D., Awad, Mark M., Borghaei, Hossein, Gainor, Justin F., Brahmer, Julie R., Spigel, David R., Reck, Martin, O’Byrne, Kenneth J., Paz‐Ares, Luis, Zerba, Kim E., Li, Xuemei, Geese, William J., Green, George, Lestini, Brian, Szustakowski, Joseph D., Chang, Han, Ready, Neal

Year: 2018

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2018-ct078

Paper Hyperthermic Intrathoracic Chemotherapy (HITOC) Improves Malignant Pleural Mesothelioma Control Through a Tumor Specific Cytotoxic Immune Response

Cavin, Sabrina, Hao, Yameng, Gkasti, Aspasia, Chriqui, Louis-Emmanuel, Marié, Damien, Abdelnour, Etienne, González, Michel, Krueger, Thorsten, Dyson, Paul J., Peters, Solange, Meylan, Etienne, Perentes, Jean Yannis · 2023 · British journal of surgery · DOI

Full title: Hyperthermic Intrathoracic Chemotherapy (HITOC) Improves Malignant Pleural Mesothelioma Control Through a Tumor Specific Cytotoxic Immune Response

Authors: Cavin, Sabrina, Hao, Yameng, Gkasti, Aspasia, Chriqui, Louis-Emmanuel, Marié, Damien, Abdelnour, Etienne, González, Michel, Krueger, Thorsten, Dyson, Paul J., Peters, Solange, Meylan, Etienne, Perentes, Jean Yannis

Year: 2023

Venue: British journal of surgery

DOI: https://doi.org/10.1093/bjs/znad178.002

Paper Abstract 6189: Development of an anti hepatocellular carcinoma CAR T strategy targeting PDL1

Kyung-Sik Lee, Hye‐Seong Park, G. Park, Gi‐Chan Lee, Eunyoung Choi, Jae-in Yu, Seung-Jo Yang, Mihwa Kim, Y. Choi, Je-Jung Lee, J. Rhee, B. Park, J. Park · 2022 · Cancer Research · DOI

Full title: Abstract 6189: Development of an anti hepatocellular carcinoma CAR T strategy targeting PDL1

Authors: Kyung-Sik Lee, Hye‐Seong Park, G. Park, Gi‐Chan Lee, Eunyoung Choi, Jae-in Yu, Seung-Jo Yang, Mihwa Kim, Y. Choi, Je-Jung Lee, J. Rhee, B. Park, J. Park

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2022-6189

Paper Exploring novel immune-related toxicities and endpoints with immune-checkpoint inhibitors in non-small cell lung cancer.

Chow, Laura Q M · 2013 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Exploring novel immune-related toxicities and endpoints with immune-checkpoint inhibitors in non-small cell lung cancer.

Authors: Chow, Laura Q M

Year: 2013

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.14694/EdBook_AM.2013.33.e280

Paper Investigation of poor predictive factors in extensive stage small cell lung cancer under etoposide‐platinum‐atezolizumab treatment

Jeong Uk Lim, H. Kang, A. Shin, C. Yeo, Sung Kyoung Kim, Jin Woo Kim, Seung Joon Kim, S. H. Lee · 2022 · Thoracic Cancer · DOI

Full title: Investigation of poor predictive factors in extensive stage small cell lung cancer under etoposide‐platinum‐atezolizumab treatment

Authors: Jeong Uk Lim, H. Kang, A. Shin, C. Yeo, Sung Kyoung Kim, Jin Woo Kim, Seung Joon Kim, S. H. Lee

Year: 2022

Venue: Thoracic Cancer

DOI: https://doi.org/10.1111/1759-7714.14697

Paper A COMPREHENSIVE REVIEW OF NIVOLUMAB AND IPILIMUMAB COMBINATION THERAPY IN ADVANCED MELANOMA

Subashini, R., Bi, A. Mubina, Roshika, S., Harini, V., Jayasri, S., Sri, S. Pooja · 2026 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: A COMPREHENSIVE REVIEW OF NIVOLUMAB AND IPILIMUMAB COMBINATION THERAPY IN ADVANCED MELANOMA

Authors: Subashini, R., Bi, A. Mubina, Roshika, S., Harini, V., Jayasri, S., Sri, S. Pooja

Year: 2026

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.18790277

Paper Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Literature.

Mobini, Narciss, Dhillon, Rummit, Dickey, Jason, Spoon, Jordan, Sadrolashrafi, Kaviyon · 2019 · Case reports in dermatological medicine · DOI

Full title: Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Literature.

Authors: Mobini, Narciss, Dhillon, Rummit, Dickey, Jason, Spoon, Jordan, Sadrolashrafi, Kaviyon

Year: 2019

Venue: Case reports in dermatological medicine

DOI: https://doi.org/10.1155/2019/6702870

Paper Anti-CTLA-4 antibody-functionalized dendritic cell-derived exosomes targeting tumor-draining lymph nodes for effective induction of antitumor T-cell responses.

Phung, Cao Dai, Pham, Thanh Tung, Nguyen, Hanh Thuy, Nguyen, Tien Tiep, Ou, Wenquan, Jeong, Jee-Heon, Choi, Han-Gon, Ku, Sae Kwang, Yong, Chul Soon, Kim, Jong Oh · 2020 · Acta biomaterialia · DOI

Full title: Anti-CTLA-4 antibody-functionalized dendritic cell-derived exosomes targeting tumor-draining lymph nodes for effective induction of antitumor T-cell responses.

Authors: Phung, Cao Dai, Pham, Thanh Tung, Nguyen, Hanh Thuy, Nguyen, Tien Tiep, Ou, Wenquan, Jeong, Jee-Heon, Choi, Han-Gon, Ku, Sae Kwang, Yong, Chul Soon, Kim, Jong Oh

Year: 2020

Venue: Acta biomaterialia

DOI: https://doi.org/10.1016/j.actbio.2020.08.008

Paper Efficacy and predictive biomarkers of immunotherapy in Epstein-Barr virus-associated gastric cancer.

Bai, Yuezong, Xie, Tong, Wang, Zhenghang, Tong, Shuang, Zhao, Xiaochen, Zhao, Feilong, Cai, Jinping, Wei, Xiaofan, Peng, Zhi, Shen, Lin · 2022 · Journal for immunotherapy of cancer · DOI

Full title: Efficacy and predictive biomarkers of immunotherapy in Epstein-Barr virus-associated gastric cancer.

Authors: Bai, Yuezong, Xie, Tong, Wang, Zhenghang, Tong, Shuang, Zhao, Xiaochen, Zhao, Feilong, Cai, Jinping, Wei, Xiaofan, Peng, Zhi, Shen, Lin

Year: 2022

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2021-004080

Paper [Advanced bladder cancer : From chemo- to immunotherapy].

Horn, T, Krege, S, Retz, M · 2018 · Der Urologe. Ausg. A · DOI

Full title: [Advanced bladder cancer : From chemo- to immunotherapy].

Authors: Horn, T, Krege, S, Retz, M

Year: 2018

Venue: Der Urologe. Ausg. A

DOI: https://doi.org/10.1007/s00120-018-0626-2

Paper Data from Bladder Preservation with Durvalumab plus Tremelimumab and Concurrent Radiotherapy in Patients with Localized Muscle-Invasive Bladder Cancer (IMMUNOPRESERVE): A Phase II Spanish Oncology GenitoUrinary Group Trial

Muro, Xavier García del, Valderrama, Begoña P., Medina, Ana, Etxániz, Olatz, Sarrió, Regina Gironés, Juan-Fita, María José, Costa-García, Marcel, Moreno, Rafael, Rodríguez, Isabel Miras, Ortiz, Irene, Cuéllar, Andrés, Ferrer, F., Vigués, Francesc, Piedra, Roberto de Haro, Gómez, Arturo Candal, Villà, S., Pontones, José Luís, Murria, Yasmina, Lendínez‐Cano, Guillermo, Alemany, Ramón · 2025 · DOI

Full title: Data from Bladder Preservation with Durvalumab plus Tremelimumab and Concurrent Radiotherapy in Patients with Localized Muscle-Invasive Bladder Cancer (IMMUNOPRESERVE): A Phase II Spanish Oncology GenitoUrinary Group Trial

Authors: Muro, Xavier García del, Valderrama, Begoña P., Medina, Ana, Etxániz, Olatz, Sarrió, Regina Gironés, Juan-Fita, María José, Costa-García, Marcel, Moreno, Rafael, Rodríguez, Isabel Miras, Ortiz, Irene, Cuéllar, Andrés, Ferrer, F., Vigués, Francesc, Piedra, Roberto de Haro, Gómez, Arturo Candal, Villà, S., Pontones, José Luís, Murria, Yasmina, Lendínez‐Cano, Guillermo, Alemany, Ramón

Year: 2025

DOI: https://doi.org/10.1158/1078-0432.c.7676176

Paper OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal.

Linch, Stefanie N, McNamara, Michael J, Redmond, William L · 2015 · Frontiers in oncology · DOI

Full title: OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal.

Authors: Linch, Stefanie N, McNamara, Michael J, Redmond, William L

Year: 2015

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2015.00034

Paper Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.

Mao, Wendy, Ghasemzadeh, Ali, Freeman, Zachary T, Obradovic, Aleksandar, Chaimowitz, Matthew G, Nirschl, Thomas R, McKiernan, Emily, Yegnasubramanian, Srinivasan, Drake, Charles G · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.

Authors: Mao, Wendy, Ghasemzadeh, Ali, Freeman, Zachary T, Obradovic, Aleksandar, Chaimowitz, Matthew G, Nirschl, Thomas R, McKiernan, Emily, Yegnasubramanian, Srinivasan, Drake, Charles G

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0758-y

Paper An Overview of Immune Checkpoint Inhibitors in Gynecologic Cancers.

Castellano, Tara, Moore, Kathleen N, Holman, Laura L · 2018 · Clinical therapeutics · DOI

Full title: An Overview of Immune Checkpoint Inhibitors in Gynecologic Cancers.

Authors: Castellano, Tara, Moore, Kathleen N, Holman, Laura L

Year: 2018

Venue: Clinical therapeutics

DOI: https://doi.org/10.1016/j.clinthera.2018.01.005

Paper Immunotherapy in kidney cancer

Hammers, Hans J. · 2016 · Current Opinion in Urology · DOI

Full title: Immunotherapy in kidney cancer

Authors: Hammers, Hans J.

Year: 2016

Venue: Current Opinion in Urology

DOI: https://doi.org/10.1097/mou.0000000000000338

Paper The efficacy of PD-1/PD-L1 inhibitors in advanced squamous-cell lung cancer: a meta-analysis of 3112 patients.

Chen, Rui-Lian, Zhou, Jing-Xu, Cao, Yang, Li, Sui-Hui, Li, Yong-Hao, Jiang, Mei, Lu, Dong-Yan, Li, Peng, Lin, Li-Zhu · 2019 · Immunotherapy · DOI

Full title: The efficacy of PD-1/PD-L1 inhibitors in advanced squamous-cell lung cancer: a meta-analysis of 3112 patients.

Authors: Chen, Rui-Lian, Zhou, Jing-Xu, Cao, Yang, Li, Sui-Hui, Li, Yong-Hao, Jiang, Mei, Lu, Dong-Yan, Li, Peng, Lin, Li-Zhu

Year: 2019

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2019-0101

Paper Peripheral Lymphocyte Count as a Surrogate Marker of Immune Checkpoint Inhibitor Therapy Outcomes in Patients with Non-Small-Cell Lung Cancer

Lee, Ye Jin, Park, Young Sik, Lee, Hyun Woo, Park, Tae Yun, Lee, Jung‐Kyu, Heo, Eun Young · 2021 · Research Square (Research Square) · DOI

Full title: Peripheral Lymphocyte Count as a Surrogate Marker of Immune Checkpoint Inhibitor Therapy Outcomes in Patients with Non-Small-Cell Lung Cancer

Authors: Lee, Ye Jin, Park, Young Sik, Lee, Hyun Woo, Park, Tae Yun, Lee, Jung‐Kyu, Heo, Eun Young

Year: 2021

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-601752/v1

Paper Analysis of risk factors for immune checkpoint inhibitor-associated liver injury: a retrospective analysis based on clinical study and real-world data.

Wang, Bitao, Zhuang, Shaowei, Lin, Shengnan, Lin, Jierong, Zeng, Wanxian, Du, Bin, Yang, Jing · 2025 · Hepatology international · DOI

Full title: Analysis of risk factors for immune checkpoint inhibitor-associated liver injury: a retrospective analysis based on clinical study and real-world data.

Authors: Wang, Bitao, Zhuang, Shaowei, Lin, Shengnan, Lin, Jierong, Zeng, Wanxian, Du, Bin, Yang, Jing

Year: 2025

Venue: Hepatology international

DOI: https://doi.org/10.1007/s12072-025-10783-w

Paper Paracrine release of IL-2 and anti-CTLA-4 enhances the ability of artificial polymer antigen-presenting cells to expand antigen-specific T cells and inhibit tumor growth in a mouse model.

Zhang, Lei, Wang, Limin, Shahzad, Khawar Ali, Xu, Tao, Wan, Xin, Pei, Weiya, Shen, Chuanlai · 2017 · Cancer immunology, immunotherapy : CII · DOI

Full title: Paracrine release of IL-2 and anti-CTLA-4 enhances the ability of artificial polymer antigen-presenting cells to expand antigen-specific T cells and inhibit tumor growth in a mouse model.

Authors: Zhang, Lei, Wang, Limin, Shahzad, Khawar Ali, Xu, Tao, Wan, Xin, Pei, Weiya, Shen, Chuanlai

Year: 2017

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-017-2016-9

Paper Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response

Thomas J. LaSalle, Emily E Austin, Grant Rigney, E. Wehrenberg-Klee, Sarah Nesti, B. Larimer, U. Mahmood · 2020 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response

Authors: Thomas J. LaSalle, Emily E Austin, Grant Rigney, E. Wehrenberg-Klee, Sarah Nesti, B. Larimer, U. Mahmood

Year: 2020

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2019-000291

Paper Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.

Thudium, Kent, Selby, Mark, Zorn, Julie A, Rak, Gregory, Wang, Xi-Tao, Bunch, Roderick Todd, Hogan, Jason M, Strop, Pavel, Korman, Alan J · 2022 · Cancer immunology research · DOI

Full title: Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.

Authors: Thudium, Kent, Selby, Mark, Zorn, Julie A, Rak, Gregory, Wang, Xi-Tao, Bunch, Roderick Todd, Hogan, Jason M, Strop, Pavel, Korman, Alan J

Year: 2022

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-22-0057

Paper Hepatotoxicity of immune checkpoint inhibitors: What is Currently Known.

Zheng, Caiyun, Huang, Shunmin, Lin, Meimei, Hong, Baohui, Ni, Ruping, Dai, Hengfen, Lin, Xiuqin, Yang, Jing · 2023 · Hepatology communications · DOI

Full title: Hepatotoxicity of immune checkpoint inhibitors: What is Currently Known.

Authors: Zheng, Caiyun, Huang, Shunmin, Lin, Meimei, Hong, Baohui, Ni, Ruping, Dai, Hengfen, Lin, Xiuqin, Yang, Jing

Year: 2023

Venue: Hepatology communications

DOI: https://doi.org/10.1097/HC9.0000000000000063

Paper Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.

Kim, Kwang-Soo, Habashy, Karl, Gould, Andrew, Zhao, Junfei, Najem, Hinda, Amidei, Christina, Saganty, Ruth, Arrieta, Víctor A, Dmello, Crismita, Chen, Li, Zhang, Daniel Y, Castro, Brandyn, Billingham, Leah, Levey, Daniel, Huber, Olivia, Marques, Marilyn, Savitsky, David A, Morin, Benjamin M, Muzzio, Miguel, Canney, Michael, Horbinski, Craig, Zhang, Peng, Miska, Jason, Padney, Surya, Zhang, Bin, Rabadan, Raul, Phillips, Joanna J, Butowski, Nicholas, Heimberger, Amy B, Hu, Jian, Stupp, Roger, Chand, Dhan, Lee-Chang, Catalina, Sonabend, Adam M · 2024 · Neuro-oncology · DOI

Full title: Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.

Authors: Kim, Kwang-Soo, Habashy, Karl, Gould, Andrew, Zhao, Junfei, Najem, Hinda, Amidei, Christina, Saganty, Ruth, Arrieta, Víctor A, Dmello, Crismita, Chen, Li, Zhang, Daniel Y, Castro, Brandyn, Billingham, Leah, Levey, Daniel, Huber, Olivia, Marques, Marilyn, Savitsky, David A, Morin, Benjamin M, Muzzio, Miguel, Canney, Michael, Horbinski, Craig, Zhang, Peng, Miska, Jason, Padney, Surya, Zhang, Bin, Rabadan, Raul, Phillips, Joanna J, Butowski, Nicholas, Heimberger, Amy B, Hu, Jian, Stupp, Roger, Chand, Dhan, Lee-Chang, Catalina, Sonabend, Adam M

Year: 2024

Venue: Neuro-oncology

DOI: https://doi.org/10.1093/neuonc/noae135

Paper Anti-PD-1-Induced Pneumonitis Is Associated with Persistent Imaging Abnormalities in Melanoma Patients.

Johnson, Douglas B, Taylor, Kevin B, Cohen, Justine V, Ayoubi, Noura, Haugh, Alexandra M, Wang, Daniel Y, Schlick, Brian D, Voorhees, Amber L, Gage, Kenneth L, Fintelmann, Florian J, Sullivan, Ryan J, Eroglu, Zeynep, Abramson, Richard G · 2019 · Cancer immunology research · DOI

Full title: Anti-PD-1-Induced Pneumonitis Is Associated with Persistent Imaging Abnormalities in Melanoma Patients.

Authors: Johnson, Douglas B, Taylor, Kevin B, Cohen, Justine V, Ayoubi, Noura, Haugh, Alexandra M, Wang, Daniel Y, Schlick, Brian D, Voorhees, Amber L, Gage, Kenneth L, Fintelmann, Florian J, Sullivan, Ryan J, Eroglu, Zeynep, Abramson, Richard G

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0717

Paper Screening for the drugs that increase the efficacy of poly(ADP-ribose) polymerase inhibitor by the FDA-approved compounds library

Okui, Yosuke, Ohta, Tsuyoshi, Nagase, Satoru · 2023 · DOI

Full title: Screening for the drugs that increase the efficacy of poly(ADP-ribose) polymerase inhibitor by the FDA-approved compounds library

Authors: Okui, Yosuke, Ohta, Tsuyoshi, Nagase, Satoru

Year: 2023

DOI: https://doi.org/10.3802/jgo.2023.34.s1.o40

Paper First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges.

Rizzo, Alessandro, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni · 2021 · Expert review of gastroenterology & hepatology · DOI

Full title: First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges.

Authors: Rizzo, Alessandro, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni

Year: 2021

Venue: Expert review of gastroenterology & hepatology

DOI: https://doi.org/10.1080/17474124.2021.1973431

Paper A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti–PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors.

Callahan, Margaret K., Ott, Patrick A., Odunsi, Kunle, Bertolini, Stephane V., Pan, Linda, Venhaus, Ralph, Karakunnel, Joyson, Hodi, F. Stephen, Wolchok, Jedd D. · 2014 · Journal of Clinical Oncology · DOI

Full title: A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti–PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors.

Authors: Callahan, Margaret K., Ott, Patrick A., Odunsi, Kunle, Bertolini, Stephane V., Pan, Linda, Venhaus, Ralph, Karakunnel, Joyson, Hodi, F. Stephen, Wolchok, Jedd D.

Year: 2014

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2014.32.15_suppl.tps3120

Paper Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model.

Padrón, Álvaro, Hurez, Vincent, Gupta, Harshita B, Clark, Curtis A, Pandeswara, Sri Lakshmi, Yuan, Bin, Svatek, Robert S, Turk, Mary Jo, Drerup, Justin M, Li, Rong, Curiel, Tyler J · 2018 · Experimental gerontology · DOI

Full title: Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model.

Authors: Padrón, Álvaro, Hurez, Vincent, Gupta, Harshita B, Clark, Curtis A, Pandeswara, Sri Lakshmi, Yuan, Bin, Svatek, Robert S, Turk, Mary Jo, Drerup, Justin M, Li, Rong, Curiel, Tyler J

Year: 2018

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2017.12.025

Paper Current status of treatment with immune checkpoint inhibitors for gastrointestinal, hepatobiliary, and pancreatic cancers.

Eso, Yuji, Seno, Hiroshi · 2020 · Therapeutic advances in gastroenterology · DOI

Full title: Current status of treatment with immune checkpoint inhibitors for gastrointestinal, hepatobiliary, and pancreatic cancers.

Authors: Eso, Yuji, Seno, Hiroshi

Year: 2020

Venue: Therapeutic advances in gastroenterology

DOI: https://doi.org/10.1177/1756284820948773

Paper KS05.5.A REPETITIVE INTRACRANIAL INJECTION OF NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECEPTOR ALONE AND IN COMBINATION WITH SYSTEMIC ANTI-PD-1 CHECKPOINT INHIBITION IN PATIENTS WITH RECURRENT GLIOBLASTOMA

M. Burger, E. Ehrend, F. Strassheimer, P. Cakmak, H. Krenzlin, P. Elleringmann, P. Zeiner, S. Herkt, I. Poschke, J. Macas, K. Weber, J. Schupp, J. Lun, C. Opitz, B. Roller, P. Manns, S. Klinsing, S. Breuer, S. Hehlgans, S. Lee, I. Mildenberger, G. Ludmirski, J. Hermann, E. Müller, M. Schmitz, M. Mehlitz, C. Senft, P. Harter, M. Rieger, F. Rödel, M. Czabanka, M. Ratliff, M. Platten, C. Herold-Mende, F. Ringel, E. Herrmann, E. Hattingen, Y. Reiss, L. Bunse, H. Bonig, K. Plate, M. Forster, T. Tonn, W. Wels, J. Steinbach · 2024 · Neuro-Oncology · DOI

Full title: KS05.5.A REPETITIVE INTRACRANIAL INJECTION OF NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECEPTOR ALONE AND IN COMBINATION WITH SYSTEMIC ANTI-PD-1 CHECKPOINT INHIBITION IN PATIENTS WITH RECURRENT GLIOBLASTOMA

Authors: M. Burger, E. Ehrend, F. Strassheimer, P. Cakmak, H. Krenzlin, P. Elleringmann, P. Zeiner, S. Herkt, I. Poschke, J. Macas, K. Weber, J. Schupp, J. Lun, C. Opitz, B. Roller, P. Manns, S. Klinsing, S. Breuer, S. Hehlgans, S. Lee, I. Mildenberger, G. Ludmirski, J. Hermann, E. Müller, M. Schmitz, M. Mehlitz, C. Senft, P. Harter, M. Rieger, F. Rödel, M. Czabanka, M. Ratliff, M. Platten, C. Herold-Mende, F. Ringel, E. Herrmann, E. Hattingen, Y. Reiss, L. Bunse, H. Bonig, K. Plate, M. Forster, T. Tonn, W. Wels, J. Steinbach

Year: 2024

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noae144.018

Paper Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs.

Allard, Bertrand, Pommey, Sandra, Smyth, Mark J, Stagg, John · 2013 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs.

Authors: Allard, Bertrand, Pommey, Sandra, Smyth, Mark J, Stagg, John

Year: 2013

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-13-0545

Paper Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.

Rudqvist, Nils-Petter, Pilones, Karsten A, Lhuillier, Claire, Wennerberg, Erik, Sidhom, John-William, Emerson, Ryan O, Robins, Harlan S, Schneck, Jonathan, Formenti, Silvia C, Demaria, Sandra · 2018 · Cancer immunology research · DOI

Full title: Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.

Authors: Rudqvist, Nils-Petter, Pilones, Karsten A, Lhuillier, Claire, Wennerberg, Erik, Sidhom, John-William, Emerson, Ryan O, Robins, Harlan S, Schneck, Jonathan, Formenti, Silvia C, Demaria, Sandra

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-17-0134

Paper Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti‐CTLA4 and anti‐PD1 combination immunotherapy: Incidence, management, and clinical benefit

Anisha B. Patel, Sahira Farooq, Macartney Welborn, R. Amaria, S. Chon, A. Diab, Isabella C. Glitza Oliva, A. Huen, Shirley Q. Li, K. Nelson, Omar Pacha, S. Patel, R. Rapini, H. Tawbi, M. Wong, J. McQuade, M. Davies, L. Haydu · 2021 · Cancer · DOI

Full title: Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti‐CTLA4 and anti‐PD1 combination immunotherapy: Incidence, management, and clinical benefit

Authors: Anisha B. Patel, Sahira Farooq, Macartney Welborn, R. Amaria, S. Chon, A. Diab, Isabella C. Glitza Oliva, A. Huen, Shirley Q. Li, K. Nelson, Omar Pacha, S. Patel, R. Rapini, H. Tawbi, M. Wong, J. McQuade, M. Davies, L. Haydu

Year: 2021

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.34004

Paper [Immune Checkpoint Inhibitor Related Enterocolitis].

Hamamoto, Yasuo · 2020 · Gan to kagaku ryoho. Cancer & chemotherapy

Full title: [Immune Checkpoint Inhibitor Related Enterocolitis].

Authors: Hamamoto, Yasuo

Year: 2020

Venue: Gan to kagaku ryoho. Cancer & chemotherapy

Paper Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule

Berezhnoy, Alexey, Sumrow, Bradley, Stahl, Kurt, Shah, Kalpana, Liu, Daorong, Li, Jonathan, Hao, Su-Shin, Costa, Anushka De, Kaul, Sanjeev, Bendell, Johanna C., Coté, Gregory M., Luke, Jason J., Sanborn, Rachel E., Sharma, Manish, Chen, Francine, Li, Hua, Diedrich, Gundo, Bonvini, Ezio, Moore, Paul A. · 2020 · Cell Reports Medicine · DOI

Full title: Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule

Authors: Berezhnoy, Alexey, Sumrow, Bradley, Stahl, Kurt, Shah, Kalpana, Liu, Daorong, Li, Jonathan, Hao, Su-Shin, Costa, Anushka De, Kaul, Sanjeev, Bendell, Johanna C., Coté, Gregory M., Luke, Jason J., Sanborn, Rachel E., Sharma, Manish, Chen, Francine, Li, Hua, Diedrich, Gundo, Bonvini, Ezio, Moore, Paul A.

Year: 2020

Venue: Cell Reports Medicine

DOI: https://doi.org/10.1016/j.xcrm.2020.100163

Paper Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management.

Lomax, Anna J, Lim, Jennifer, Cheng, Robert, Sweeting, Arianne, Lowe, Patricia, McGill, Neil, Shackel, Nicholas, Chua, Elizabeth L, McNeil, Catriona · 2018 · Journal of skin cancer · DOI

Full title: Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management.

Authors: Lomax, Anna J, Lim, Jennifer, Cheng, Robert, Sweeting, Arianne, Lowe, Patricia, McGill, Neil, Shackel, Nicholas, Chua, Elizabeth L, McNeil, Catriona

Year: 2018

Venue: Journal of skin cancer

DOI: https://doi.org/10.1155/2018/9602540

Paper Advances in immunotherapy for colorectal cancer: overcoming resistance in mismatch repair-proficient tumors.

Keivany, Mohammad Reza, Shojae, Elham, Besharatloo, Mohammadreza, Latifi, Hanieh, Barjasteh, Amir Hossein · 2026 · Cancer cell international · DOI

Full title: Advances in immunotherapy for colorectal cancer: overcoming resistance in mismatch repair-proficient tumors.

Authors: Keivany, Mohammad Reza, Shojae, Elham, Besharatloo, Mohammadreza, Latifi, Hanieh, Barjasteh, Amir Hossein

Year: 2026

Venue: Cancer cell international

DOI: https://doi.org/10.1186/s12935-026-04177-7

Paper Combination immunotherapy of glioblastoma with dendritic cell cancer vaccines, anti-PD-1 and poly I:C.

Zhu, Ping, Li, Shi-You, Ding, Jin, Fei, Zhou, Sun, Sheng-Nan, Zheng, Zhao-Hui, Wei, Ding, Jiang, Jun, Miao, Jin-Lin, Li, San-Zhong, Luo, Xing, Zhang, Kui, Wang, Bin, Zhang, Kun, Pu, Su, Wang, Qian-Ting, Zhang, Xin-Yue, Wen, Gao-Liu, Liu, Jun O, August, John Thomas, Bian, Huijie, Chen, Zhi-Nan, He, You-Wen · 2023 · Journal of pharmaceutical analysis · DOI

Full title: Combination immunotherapy of glioblastoma with dendritic cell cancer vaccines, anti-PD-1 and poly I:C.

Authors: Zhu, Ping, Li, Shi-You, Ding, Jin, Fei, Zhou, Sun, Sheng-Nan, Zheng, Zhao-Hui, Wei, Ding, Jiang, Jun, Miao, Jin-Lin, Li, San-Zhong, Luo, Xing, Zhang, Kui, Wang, Bin, Zhang, Kun, Pu, Su, Wang, Qian-Ting, Zhang, Xin-Yue, Wen, Gao-Liu, Liu, Jun O, August, John Thomas, Bian, Huijie, Chen, Zhi-Nan, He, You-Wen

Year: 2023

Venue: Journal of pharmaceutical analysis

DOI: https://doi.org/10.1016/j.jpha.2023.04.012

Paper Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients.

Kwek, Serena S, Dao, Vinh, Roy, Ritu, Hou, Yafei, Alajajian, David, Simko, Jeffrey P, Small, Eric J, Fong, Lawrence · 2012 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients.

Authors: Kwek, Serena S, Dao, Vinh, Roy, Ritu, Hou, Yafei, Alajajian, David, Simko, Jeffrey P, Small, Eric J, Fong, Lawrence

Year: 2012

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.1201529

Paper Checkpoint Inhibitors.

Heinzerling, Lucie, de Toni, Enrico N, Schett, Georg, Hundorfean, Gheorghe, Zimmer, Lisa · 2019 · Deutsches Arzteblatt international · DOI

Full title: Checkpoint Inhibitors.

Authors: Heinzerling, Lucie, de Toni, Enrico N, Schett, Georg, Hundorfean, Gheorghe, Zimmer, Lisa

Year: 2019

Venue: Deutsches Arzteblatt international

DOI: https://doi.org/10.3238/arztebl.2019.0119

Paper The change of serum C-reactive protein levels during molecular-targeted treatments could predict the response to anti-PD-1 treatment in metastatic renal cell carcinoma patients.

Kimiharu Takamatsu, R. Mizuno, N. Hayakawa, N. Tanaka, T. Kosaka, E. Kikuchi, M. Oya · 2020 · DOI

Full title: The change of serum C-reactive protein levels during molecular-targeted treatments could predict the response to anti-PD-1 treatment in metastatic renal cell carcinoma patients.

Authors: Kimiharu Takamatsu, R. Mizuno, N. Hayakawa, N. Tanaka, T. Kosaka, E. Kikuchi, M. Oya

Year: 2020

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.e17085

Paper Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF.

Fong, Lawrence, Kwek, Serena S, O'Brien, Shaun, Kavanagh, Brian, McNeel, Douglas G, Weinberg, Vivian, Lin, Amy M, Rosenberg, Jonathan, Ryan, Charles J, Rini, Brian I, Small, Eric J · 2009 · Cancer research · DOI

Full title: Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF.

Authors: Fong, Lawrence, Kwek, Serena S, O'Brien, Shaun, Kavanagh, Brian, McNeel, Douglas G, Weinberg, Vivian, Lin, Amy M, Rosenberg, Jonathan, Ryan, Charles J, Rini, Brian I, Small, Eric J

Year: 2009

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-08-3529

Paper Cocktail Strategy Based on Spatio-Temporally Controlled Nano Device Improves Therapy of Breast Cancer.

Tianqun Lang, Yiran Liu, Zhong Zheng, W. Ran, Yihui Zhai, Qi Yin, Pengcheng Zhang, Yaping Li · 2019 · Advances in Materials · DOI

Full title: Cocktail Strategy Based on Spatio-Temporally Controlled Nano Device Improves Therapy of Breast Cancer.

Authors: Tianqun Lang, Yiran Liu, Zhong Zheng, W. Ran, Yihui Zhai, Qi Yin, Pengcheng Zhang, Yaping Li

Year: 2019

Venue: Advances in Materials

DOI: https://doi.org/10.1002/adma.201903844

Paper Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma

Abou‐Alfa, Ghassan K., Lau, George, Kudo, Masatoshi, Chan, Stephen L., Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, Ostapenko, Yuriy, Yau, Thomas, Azevedo, Sérgio Jobim, Varela, Marı́a, Cheng, Ann‐Lii, Qin, Shukui, Galle, Peter R., Ali, Sajid, Marcovitz, Michelle, Makowsky, Mallory, He, Philip, Kurland, John F., Negro, Alejandra, Sangro, Bruno · 2022 · NEJM Evidence · DOI

Full title: Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma

Authors: Abou‐Alfa, Ghassan K., Lau, George, Kudo, Masatoshi, Chan, Stephen L., Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, Ostapenko, Yuriy, Yau, Thomas, Azevedo, Sérgio Jobim, Varela, Marı́a, Cheng, Ann‐Lii, Qin, Shukui, Galle, Peter R., Ali, Sajid, Marcovitz, Michelle, Makowsky, Mallory, He, Philip, Kurland, John F., Negro, Alejandra, Sangro, Bruno

Year: 2022

Venue: NEJM Evidence

DOI: https://doi.org/10.1056/evidoa2100070

Paper Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities.

Coutzac, Clélia, Adam, Julien, Soularue, Emilie, Collins, Michael, Racine, Antoine, Mussini, Charlotte, Boselli, Lisa, Kamsukom, Nyam, Mateus, Christine, Charrier, Mélinda, Cassard, Lydie, Planchard, David, Ribrag, Vincent, Fizazi, Karim, Loriot, Yohann, Lepage, Patricia, Scoazec, Jean-Yves, Robert, Caroline, Carbonnel, Franck, Chaput, Nathalie · 2017 · Journal of Crohn's & colitis · DOI

Full title: Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities.

Authors: Coutzac, Clélia, Adam, Julien, Soularue, Emilie, Collins, Michael, Racine, Antoine, Mussini, Charlotte, Boselli, Lisa, Kamsukom, Nyam, Mateus, Christine, Charrier, Mélinda, Cassard, Lydie, Planchard, David, Ribrag, Vincent, Fizazi, Karim, Loriot, Yohann, Lepage, Patricia, Scoazec, Jean-Yves, Robert, Caroline, Carbonnel, Franck, Chaput, Nathalie

Year: 2017

Venue: Journal of Crohn's & colitis

DOI: https://doi.org/10.1093/ecco-jcc/jjx081

Paper In Situ Transformable Photothermal Targeting Chimeras for Spatiotemporally Controllable Protein Degradation and Combination Immunotherapy for Cancer.

Dang, Yijing, Hou, Bo, Pan, Jiaxing, Jiang, Xingyu, Zhu, Zifan, Lai, Yi, Tao, Wei, Zhang, Fan, Lammers, Twan, Tian, Yang, Yu, Haijun, Zhang, Wen, Xu, Zhiai · 2026 · Journal of the American Chemical Society · DOI

Full title: In Situ Transformable Photothermal Targeting Chimeras for Spatiotemporally Controllable Protein Degradation and Combination Immunotherapy for Cancer.

Authors: Dang, Yijing, Hou, Bo, Pan, Jiaxing, Jiang, Xingyu, Zhu, Zifan, Lai, Yi, Tao, Wei, Zhang, Fan, Lammers, Twan, Tian, Yang, Yu, Haijun, Zhang, Wen, Xu, Zhiai

Year: 2026

Venue: Journal of the American Chemical Society

DOI: https://doi.org/10.1021/jacs.5c16311

Paper Exploring novel immunotherapy in advanced esophageal squamous cell carcinoma: Is targeting TIGIT an answer?

Chuang, Chien-Huai, Guo, Jhe-Cyuan, Kato, Ken, Hsu, Chih-Hung · 2025 · Esophagus : official journal of the Japan Esophageal Society · DOI

Full title: Exploring novel immunotherapy in advanced esophageal squamous cell carcinoma: Is targeting TIGIT an answer?

Authors: Chuang, Chien-Huai, Guo, Jhe-Cyuan, Kato, Ken, Hsu, Chih-Hung

Year: 2025

Venue: Esophagus : official journal of the Japan Esophageal Society

DOI: https://doi.org/10.1007/s10388-024-01105-4

Paper Modeling the effects of combination immunotherapy on triple-negative breast cancer in syngeneic mice from PET imaging of CD4+ and CD8+ cells.

Syme, Dayton J, Davenport, Angelica A, Lu, Yun, Sorace, Anna G, Cogan, N G · 2025 · Mathematical medicine and biology : a journal of the IMA · DOI

Full title: Modeling the effects of combination immunotherapy on triple-negative breast cancer in syngeneic mice from PET imaging of CD4+ and CD8+ cells.

Authors: Syme, Dayton J, Davenport, Angelica A, Lu, Yun, Sorace, Anna G, Cogan, N G

Year: 2025

Venue: Mathematical medicine and biology : a journal of the IMA

DOI: https://doi.org/10.1093/imammb/dqaf009

Paper [Endocrinopathies induced by immune checkpoint inhibitors].

Jaafar, Jaafar, Mavromati, Maria, Philippe, Jacques · 2018 · Revue medicale suisse

Full title: [Endocrinopathies induced by immune checkpoint inhibitors].

Authors: Jaafar, Jaafar, Mavromati, Maria, Philippe, Jacques

Year: 2018

Venue: Revue medicale suisse

Paper Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial.

van Dijk, Nick, Gil-Jimenez, Alberto, Silina, Karina, Hendricksen, Kees, Smit, Laura A, de Feijter, Jeantine M, van Montfoort, Maurits L, van Rooijen, Charlotte, Peters, Dennis, Broeks, Annegien, van der Poel, Henk G, Bruining, Annemarie, Lubeck, Yoni, Sikorska, Karolina, Boellaard, Thierry N, Kvistborg, Pia, Vis, Daniel J, Hooijberg, Erik, Schumacher, Ton N, van den Broek, Maries, Wessels, Lodewyk F A, Blank, Christian U, van Rhijn, Bas W, van der Heijden, Michiel S · 2020 · Nature medicine · DOI

Full title: Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial.

Authors: van Dijk, Nick, Gil-Jimenez, Alberto, Silina, Karina, Hendricksen, Kees, Smit, Laura A, de Feijter, Jeantine M, van Montfoort, Maurits L, van Rooijen, Charlotte, Peters, Dennis, Broeks, Annegien, van der Poel, Henk G, Bruining, Annemarie, Lubeck, Yoni, Sikorska, Karolina, Boellaard, Thierry N, Kvistborg, Pia, Vis, Daniel J, Hooijberg, Erik, Schumacher, Ton N, van den Broek, Maries, Wessels, Lodewyk F A, Blank, Christian U, van Rhijn, Bas W, van der Heijden, Michiel S

Year: 2020

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-020-1085-z

Paper Combination immunotherapy: a road map The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

P. Ott, F. Hodi, H. Kaufman, J. Wigginton, J. Wolchok · 2017

Full title: Combination immunotherapy: a road map The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Authors: P. Ott, F. Hodi, H. Kaufman, J. Wigginton, J. Wolchok

Year: 2017

Paper Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.

Wei, Spencer C, Levine, Jacob H, Cogdill, Alexandria P, Zhao, Yang, Anang, Nana-Ama A S, Andrews, Miles C, Sharma, Padmanee, Wang, Jing, Wargo, Jennifer A, Pe'er, Dana, Allison, James P · 2017 · Cell · DOI

Full title: Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.

Authors: Wei, Spencer C, Levine, Jacob H, Cogdill, Alexandria P, Zhao, Yang, Anang, Nana-Ama A S, Andrews, Miles C, Sharma, Padmanee, Wang, Jing, Wargo, Jennifer A, Pe'er, Dana, Allison, James P

Year: 2017

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2017.07.024

Paper Thyroid disorders induced by checkpoint inhibitors.

Ferrari, Silvia Martina, Fallahi, Poupak, Galetta, Fabio, Citi, Emanuele, Benvenga, Salvatore, Antonelli, Alessandro · 2018 · Reviews in endocrine & metabolic disorders · DOI

Full title: Thyroid disorders induced by checkpoint inhibitors.

Authors: Ferrari, Silvia Martina, Fallahi, Poupak, Galetta, Fabio, Citi, Emanuele, Benvenga, Salvatore, Antonelli, Alessandro

Year: 2018

Venue: Reviews in endocrine & metabolic disorders

DOI: https://doi.org/10.1007/s11154-018-9463-2

Paper Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy.

Olivo Pimentel, Veronica, Marcus, Damiënne, van der Wiel, Alexander Ma, Lieuwes, Natasja G, Biemans, Rianne, Lieverse, Relinde Iy, Neri, Dario, Theys, Jan, Yaromina, Ala, Dubois, Ludwig J, Lambin, Philippe · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy.

Authors: Olivo Pimentel, Veronica, Marcus, Damiënne, van der Wiel, Alexander Ma, Lieuwes, Natasja G, Biemans, Rianne, Lieverse, Relinde Iy, Neri, Dario, Theys, Jan, Yaromina, Ala, Dubois, Ludwig J, Lambin, Philippe

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-001764

Paper Dual immune checkpoint blockade in hepatocellular carcinoma: where do we stand?

Carloni, Riccardo, Rizzo, Alessandro, Ricci, Angela Dalia, Frega, Giorgio, Federico, Alessandro Di, Palloni, Andrea, Marco, Mariacristina Di, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni · 2022 · Future oncology (London, England) · DOI

Full title: Dual immune checkpoint blockade in hepatocellular carcinoma: where do we stand?

Authors: Carloni, Riccardo, Rizzo, Alessandro, Ricci, Angela Dalia, Frega, Giorgio, Federico, Alessandro Di, Palloni, Andrea, Marco, Mariacristina Di, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni

Year: 2022

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2021-0905

Paper Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas

Scheetz, Lindsay, Kadiyala, Padma, Sun, Xiaoqi, Son, Sejin, Najafabadi, Alireza Hassani, Aikins, Marisa, Löwenstein, Pedro R., Schwendeman, Anna, Castro, María G., Moon, James J. · 2020 · Clinical Cancer Research · DOI

Full title: Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas

Authors: Scheetz, Lindsay, Kadiyala, Padma, Sun, Xiaoqi, Son, Sejin, Najafabadi, Alireza Hassani, Aikins, Marisa, Löwenstein, Pedro R., Schwendeman, Anna, Castro, María G., Moon, James J.

Year: 2020

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-20-0341

Paper Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance.

Schwarz, A, Beissert, S, Grosse-Heitmeyer, K, Gunzer, M, Bluestone, J A, Grabbe, S, Schwarz, T · 2000 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance.

Authors: Schwarz, A, Beissert, S, Grosse-Heitmeyer, K, Gunzer, M, Bluestone, J A, Grabbe, S, Schwarz, T

Year: 2000

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.165.4.1824

Paper Dermatologic infections in cancer patients treated with checkpoint inhibitors.

Do, Mytrang H, Barrios, Dulce M, Phillips, Gregory S, Postow, Michael A, Warner, Allison Betof, Rosenberg, Jonathan E, Noor, Sarah J, Markova, Alina, Lacouture, Mario E · 2021 · Journal of the American Academy of Dermatology · DOI

Full title: Dermatologic infections in cancer patients treated with checkpoint inhibitors.

Authors: Do, Mytrang H, Barrios, Dulce M, Phillips, Gregory S, Postow, Michael A, Warner, Allison Betof, Rosenberg, Jonathan E, Noor, Sarah J, Markova, Alina, Lacouture, Mario E

Year: 2021

Venue: Journal of the American Academy of Dermatology

DOI: https://doi.org/10.1016/j.jaad.2021.03.039

Paper Immunologic tumor microenvironment modulators for turning cold tumors hot

Khosravi, Gholamreza, Mostafavi, Samaneh, Bastan, Sanaz, Ebrahimi, Narges, Gharibvand, Roya Safari, Eskandari, Nahid · 2024 · Cancer Communications · DOI

Full title: Immunologic tumor microenvironment modulators for turning cold tumors hot

Authors: Khosravi, Gholamreza, Mostafavi, Samaneh, Bastan, Sanaz, Ebrahimi, Narges, Gharibvand, Roya Safari, Eskandari, Nahid

Year: 2024

Venue: Cancer Communications

DOI: https://doi.org/10.1002/cac2.12539

Paper Impact of platinum-based chemotherapy and CTLA-4 inhibition on acquired resistance to first-line anti-PD-1/PD-L1 agents in non-small cell lung cancer: a systematic review and reconstructed individual patient data analysis.

Oresti, Sara, Salomone, Fabio, Nuccio, Antonio, Ogliari, Francesca Rita, Riva, Silvia Teresa, Mollica, Ludovica, Bulotta, Alessandra, Viganò, Maria Grazia, Venanzi, Francesco Maria, Passaretti, Francesco, Papotto, Ludovica, Di Lello, Anna, Ferrara, Michele, Foggetti, Giorgia, Damiano, Giuseppe, Servetto, Alberto, Califano, Raffaele, Di Maio, Massimo, Ricciuti, Biagio, Cortellini, Alessio, Reck, Martin, Cinquini, Michela, Torri, Valter, Viscardi, Giuseppe, Ferrara, Roberto · 2025 · EClinicalMedicine · DOI

Full title: Impact of platinum-based chemotherapy and CTLA-4 inhibition on acquired resistance to first-line anti-PD-1/PD-L1 agents in non-small cell lung cancer: a systematic review and reconstructed individual patient data analysis.

Authors: Oresti, Sara, Salomone, Fabio, Nuccio, Antonio, Ogliari, Francesca Rita, Riva, Silvia Teresa, Mollica, Ludovica, Bulotta, Alessandra, Viganò, Maria Grazia, Venanzi, Francesco Maria, Passaretti, Francesco, Papotto, Ludovica, Di Lello, Anna, Ferrara, Michele, Foggetti, Giorgia, Damiano, Giuseppe, Servetto, Alberto, Califano, Raffaele, Di Maio, Massimo, Ricciuti, Biagio, Cortellini, Alessio, Reck, Martin, Cinquini, Michela, Torri, Valter, Viscardi, Giuseppe, Ferrara, Roberto

Year: 2025

Venue: EClinicalMedicine

DOI: https://doi.org/10.1016/j.eclinm.2025.103482

Paper Combining forces: the promise and peril of synergistic immune checkpoint blockade and targeted therapy in metastatic melanoma.

Hermel, David J, Ott, Patrick A · 2017 · Cancer metastasis reviews · DOI

Full title: Combining forces: the promise and peril of synergistic immune checkpoint blockade and targeted therapy in metastatic melanoma.

Authors: Hermel, David J, Ott, Patrick A

Year: 2017

Venue: Cancer metastasis reviews

DOI: https://doi.org/10.1007/s10555-017-9656-2

Paper Low-dose irradiation for reversing immunotherapy resistance: how to translate?

Ochoa-de-Olza, Maria, Bourhis, Jean, Coukos, George, Herrera, Fernanda G · 2022 · Journal for immunotherapy of cancer · DOI

Full title: Low-dose irradiation for reversing immunotherapy resistance: how to translate?

Authors: Ochoa-de-Olza, Maria, Bourhis, Jean, Coukos, George, Herrera, Fernanda G

Year: 2022

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2022-004939

Paper ES02.04 Concurrent, Sequential and Combination Immunotherapy Regimens in LA-NSCLC

Provencio, Mariano · 2019 · Journal of Thoracic Oncology · DOI

Full title: ES02.04 Concurrent, Sequential and Combination Immunotherapy Regimens in LA-NSCLC

Authors: Provencio, Mariano

Year: 2019

Venue: Journal of Thoracic Oncology

DOI: https://doi.org/10.1016/j.jtho.2019.08.076

Paper Molecular basis of T cell inactivation by CTLA-4.

Kyung-Mi Lee, Ellen Chuang, M. Griffin, R. Khattri, David Hong, Weiguo Zhang, D. Straus, L. Samelson, C. Thompson, J. Bluestone · 1998 · Science · DOI

Full title: Molecular basis of T cell inactivation by CTLA-4.

Authors: Kyung-Mi Lee, Ellen Chuang, M. Griffin, R. Khattri, David Hong, Weiguo Zhang, D. Straus, L. Samelson, C. Thompson, J. Bluestone

Year: 1998

Venue: Science

DOI: https://doi.org/10.1126/science.282.5397.2263

Paper Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series.

LoPiccolo, Jaclyn, Schollenberger, Megan D, Dakhil, Sumia, Rosner, Samuel, Ali, Osama, Sharfman, William H, Silk, Ann W, Bhatia, Shailender, Lipson, Evan J · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series.

Authors: LoPiccolo, Jaclyn, Schollenberger, Megan D, Dakhil, Sumia, Rosner, Samuel, Ali, Osama, Sharfman, William H, Silk, Ann W, Bhatia, Shailender, Lipson, Evan J

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0661-6

Paper DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure.

Jacobs, Liesl, De Smidt, Elien, Geukens, Nick, Declerck, Paul, Hollevoet, Kevin · 2020 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure.

Authors: Jacobs, Liesl, De Smidt, Elien, Geukens, Nick, Declerck, Paul, Hollevoet, Kevin

Year: 2020

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1016/j.ymthe.2020.02.007

Paper Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model

Morales‐Kastresana, Aizea, Sanmamed, Miguel F., Rodríguez, Inmaculada, Palazón, Asís, Martínez‐Forero, Iván, Labiano, Sara, Hervás‐Stubbs, Sandra, Sangro, Bruno, Ochoa, María C., Rouzaut, Ana, Azpilikueta, Arantza, Bolaños, Elixabet, Jure‐Kunkel, Maria, Gütgemann, Ines, Melero, Ignacio · 2013 · Clinical Cancer Research · DOI

Full title: Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model

Authors: Morales‐Kastresana, Aizea, Sanmamed, Miguel F., Rodríguez, Inmaculada, Palazón, Asís, Martínez‐Forero, Iván, Labiano, Sara, Hervás‐Stubbs, Sandra, Sangro, Bruno, Ochoa, María C., Rouzaut, Ana, Azpilikueta, Arantza, Bolaños, Elixabet, Jure‐Kunkel, Maria, Gütgemann, Ines, Melero, Ignacio

Year: 2013

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-13-1189

Paper Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma

Feng, Zipei, Puri, Sachin, Moudgil, Tarsem, Wood, William J., Hoyt, Clifford, Wang, Chichung, Urba, Walter J., Curti, Brendan D., Bifulco, Carlo, Fox, Bernard A. · 2015 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma

Authors: Feng, Zipei, Puri, Sachin, Moudgil, Tarsem, Wood, William J., Hoyt, Clifford, Wang, Chichung, Urba, Walter J., Curti, Brendan D., Bifulco, Carlo, Fox, Bernard A.

Year: 2015

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-015-0091-z

Paper NSABP FC-13 (EMPIRE): A phase II platform study of cemiplimab monotherapy or cemiplimab-based combinations in patients with colorectal cancer and minimal residual disease (MRD) after definitive therapy.

A. Saeed, G. Yothers, S. Puhalla, P. Rastogi, T. Freeman, M. Mathias, F. Seebach, N. Wolmark, T. George · 2026 · Journal of Clinical Oncology · DOI

Full title: NSABP FC-13 (EMPIRE): A phase II platform study of cemiplimab monotherapy or cemiplimab-based combinations in patients with colorectal cancer and minimal residual disease (MRD) after definitive therapy.

Authors: A. Saeed, G. Yothers, S. Puhalla, P. Rastogi, T. Freeman, M. Mathias, F. Seebach, N. Wolmark, T. George

Year: 2026

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2026.44.2_suppl.tps268

Paper Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1.

Fan, Yizeng, Dan, Weichao, Wang, Yuzhao, Ma, Zhiqiang, Jian, Yanlin, Liu, Tianjie, Li, Mengxing, Wang, Zixi, Wei, Yi, Liu, Bo, Ding, Peng, Lei, Yuzeshi, Guo, Chendong, Zeng, Jin, Yan, Xiaolong, Wei, Wenyi, Li, Lei · 2025 · Cell metabolism · DOI

Full title: Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1.

Authors: Fan, Yizeng, Dan, Weichao, Wang, Yuzhao, Ma, Zhiqiang, Jian, Yanlin, Liu, Tianjie, Li, Mengxing, Wang, Zixi, Wei, Yi, Liu, Bo, Ding, Peng, Lei, Yuzeshi, Guo, Chendong, Zeng, Jin, Yan, Xiaolong, Wei, Wenyi, Li, Lei

Year: 2025

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2024.11.012

Paper Expression of costimulatory and inhibitory receptors in FoxP3+ regulatory T cells within the tumor microenvironment: Implications for combination immunotherapy approaches

Toker, Aras, Ohashi, Pamela S. · 2019 · Advances in cancer research · DOI

Full title: Expression of costimulatory and inhibitory receptors in FoxP3+ regulatory T cells within the tumor microenvironment: Implications for combination immunotherapy approaches

Authors: Toker, Aras, Ohashi, Pamela S.

Year: 2019

Venue: Advances in cancer research

DOI: https://doi.org/10.1016/bs.acr.2019.05.001

Paper Impact of body composition on outcomes from anti-PD1 +/- anti-CTLA-4 treatment in melanoma.

Young, Arissa C, Quach, Henry T, Song, Haocan, Davis, Elizabeth J, Moslehi, Javid J, Ye, Fei, Williams, Grant R, Johnson, Douglas B · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Impact of body composition on outcomes from anti-PD1 +/- anti-CTLA-4 treatment in melanoma.

Authors: Young, Arissa C, Quach, Henry T, Song, Haocan, Davis, Elizabeth J, Moslehi, Javid J, Ye, Fei, Williams, Grant R, Johnson, Douglas B

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-000821

Paper Experience of using 1st line combination immunotherapy in patients with metastatic renal cell carcinoma

Kalpinskiy, А. S., Myslevtsev, Igor, Андрианов, А. Н., Nyushko, K. М., Головащенко, М. П., Vorobiev, N., Chertkova, Ya. L., Shirukova, I. Kh., Usanova, E. Yu., Alekseev, B. Yа. · 2021 · Cancer Urology · DOI

Full title: Experience of using 1st line combination immunotherapy in patients with metastatic renal cell carcinoma

Authors: Kalpinskiy, А. S., Myslevtsev, Igor, Андрианов, А. Н., Nyushko, K. М., Головащенко, М. П., Vorobiev, N., Chertkova, Ya. L., Shirukova, I. Kh., Usanova, E. Yu., Alekseev, B. Yа.

Year: 2021

Venue: Cancer Urology

DOI: https://doi.org/10.17650/1726-9776-2021-17-3-47-63

Paper MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.

Rodig, Scott J, Gusenleitner, Daniel, Jackson, Donald G, Gjini, Evisa, Giobbie-Hurder, Anita, Jin, Chelsea, Chang, Han, Lovitch, Scott B, Horak, Christine, Weber, Jeffrey S, Weirather, Jason L, Wolchok, Jedd D, Postow, Michael A, Pavlick, Anna C, Chesney, Jason, Hodi, F Stephen · 2018 · Science translational medicine · DOI

Full title: MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.

Authors: Rodig, Scott J, Gusenleitner, Daniel, Jackson, Donald G, Gjini, Evisa, Giobbie-Hurder, Anita, Jin, Chelsea, Chang, Han, Lovitch, Scott B, Horak, Christine, Weber, Jeffrey S, Weirather, Jason L, Wolchok, Jedd D, Postow, Michael A, Pavlick, Anna C, Chesney, Jason, Hodi, F Stephen

Year: 2018

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.aar3342

Paper Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values.

Adashek, Jacob J, Genovese, Giannicola, Tannir, Nizar M, Msaouel, Pavlos · 2020 · Cancer treatment and research communications · DOI

Full title: Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values.

Authors: Adashek, Jacob J, Genovese, Giannicola, Tannir, Nizar M, Msaouel, Pavlos

Year: 2020

Venue: Cancer treatment and research communications

DOI: https://doi.org/10.1016/j.ctarc.2020.100166

Paper Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer.

Dehno, Mojgan Naghizadeh, Li, Yutao, Weiher, Hans, Schmidt-Wolf, Ingo G H · 2020 · International journal of molecular sciences · DOI

Full title: Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer.

Authors: Dehno, Mojgan Naghizadeh, Li, Yutao, Weiher, Hans, Schmidt-Wolf, Ingo G H

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21093078

Paper Current status and perspectives of immune checkpoint inhibitors for colorectal cancer.

H. Hirano, A. Takashima, T. Hamaguchi, D. Shida, Y. Kanemitsu · 2020 · Japanese Journal of Clinical Oncology · DOI

Full title: Current status and perspectives of immune checkpoint inhibitors for colorectal cancer.

Authors: H. Hirano, A. Takashima, T. Hamaguchi, D. Shida, Y. Kanemitsu

Year: 2020

Venue: Japanese Journal of Clinical Oncology

DOI: https://doi.org/10.1093/jjco/hyaa200

Paper Selecting immuno-oncology-based drug combinations - what should we be considering?

Festino, Lucia, Vanella, Vito, Trojaniello, Claudia, Ascierto, Paolo A · 2018 · Expert review of clinical pharmacology · DOI

Full title: Selecting immuno-oncology-based drug combinations - what should we be considering?

Authors: Festino, Lucia, Vanella, Vito, Trojaniello, Claudia, Ascierto, Paolo A

Year: 2018

Venue: Expert review of clinical pharmacology

DOI: https://doi.org/10.1080/17512433.2018.1518713

Paper Nano-Immunoconjugates in Immune Checkpoint Blockade: A Dual Approach to Precision Immunotherapy and Real-Time Imaging.

Singh, Dilpreet, Bedi, Neena · 2025 · Asia-Pacific journal of clinical oncology · DOI

Full title: Nano-Immunoconjugates in Immune Checkpoint Blockade: A Dual Approach to Precision Immunotherapy and Real-Time Imaging.

Authors: Singh, Dilpreet, Bedi, Neena

Year: 2025

Venue: Asia-Pacific journal of clinical oncology

DOI: https://doi.org/10.1111/ajco.70036

Paper Improved clinical outcomes with low-dose anti-CTLA-4 (Nurulimab) plus anti-PD-1 (Prolgolimab) vs. anti-PD-1 monotherapy in advanced cutaneous melanoma: Results from the phase III OCTAVA trial.

Demidov, Lev, Samoylenko, Igor, Kharkevich, Galina, Orlova, Kristina, Moiseenko, Vladimir, Utyashev, Igor, Stroyakovskiy, Daniil, Kozlov, Vadim, Zimina, Anastasia, Mochalova, Anastasia, Demidova, Svetlana, Lyadova, Marina, Kutkovich, Andrey, Skopin, Pavel, Kovalenko, Nadezhda, Safina, Sufia, Volkov, Vitaliy, Semiletova, Yulia, Vaschenko, Vera, Kislov, Nikolay, Poltoratskiy, Artem, Shumskaya, Irina, Kolomiets, Sergey, Sobolev, Alexandr, Belogortsev, Igor, Odintsova, Svetlana, Rastogi, Sameer, Andabekov, Timur, Penkov, Konstantin, Semenova, Anna, Obukhov, Alexey, Belyakovsky, Vasiliy, Yurchenkov, Alexander, Gladkov, Oleg, Neve, Rakesh, Falaleeva, Natalia, Poddubskaya, Elena, Vaibhav, Amale, Kirtbaya, Dmitriy, Chapko, Yana, Smagina, Maria, Fadeeva, Natalya, Sorokina, Irina, Mikhailova, Evgenia, Linkova, Yulia, Zinkina-Orikhan, Arina, Lutskii, Anton, Gabidullin, Rishat, Rzaev, Roman, Kryukov, Fedor · 2025 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Improved clinical outcomes with low-dose anti-CTLA-4 (Nurulimab) plus anti-PD-1 (Prolgolimab) vs. anti-PD-1 monotherapy in advanced cutaneous melanoma: Results from the phase III OCTAVA trial.

Authors: Demidov, Lev, Samoylenko, Igor, Kharkevich, Galina, Orlova, Kristina, Moiseenko, Vladimir, Utyashev, Igor, Stroyakovskiy, Daniil, Kozlov, Vadim, Zimina, Anastasia, Mochalova, Anastasia, Demidova, Svetlana, Lyadova, Marina, Kutkovich, Andrey, Skopin, Pavel, Kovalenko, Nadezhda, Safina, Sufia, Volkov, Vitaliy, Semiletova, Yulia, Vaschenko, Vera, Kislov, Nikolay, Poltoratskiy, Artem, Shumskaya, Irina, Kolomiets, Sergey, Sobolev, Alexandr, Belogortsev, Igor, Odintsova, Svetlana, Rastogi, Sameer, Andabekov, Timur, Penkov, Konstantin, Semenova, Anna, Obukhov, Alexey, Belyakovsky, Vasiliy, Yurchenkov, Alexander, Gladkov, Oleg, Neve, Rakesh, Falaleeva, Natalia, Poddubskaya, Elena, Vaibhav, Amale, Kirtbaya, Dmitriy, Chapko, Yana, Smagina, Maria, Fadeeva, Natalya, Sorokina, Irina, Mikhailova, Evgenia, Linkova, Yulia, Zinkina-Orikhan, Arina, Lutskii, Anton, Gabidullin, Rishat, Rzaev, Roman, Kryukov, Fedor

Year: 2025

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2025.115674

Paper Reviewer #2 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: Reviewer #2 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2.sa1

Paper A new strategy for immunotherapy of microsatellite-stable (MSS)-type advanced colorectal cancer: Multi-pathway combination therapy with PD-1/PD-L1 inhibitors.

Cai, Lingli, Chen, Anqi, Tang, Dong · 2024 · Immunology · DOI

Full title: A new strategy for immunotherapy of microsatellite-stable (MSS)-type advanced colorectal cancer: Multi-pathway combination therapy with PD-1/PD-L1 inhibitors.

Authors: Cai, Lingli, Chen, Anqi, Tang, Dong

Year: 2024

Venue: Immunology

DOI: https://doi.org/10.1111/imm.13785

Paper Immune checkpoint inhibitor-related acral vasculitis.

Comont, Thibault, Sibaud, Vincent, Mourey, Loïc, Cougoul, Pierre, Beyne-Rauzy, Odile · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Immune checkpoint inhibitor-related acral vasculitis.

Authors: Comont, Thibault, Sibaud, Vincent, Mourey, Loïc, Cougoul, Pierre, Beyne-Rauzy, Odile

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0443-6

Paper 457 KEYNOTE-495/KeyImPaCT: interim analysis of a randomized, biomarker-directed, phase 2 trial of pembrolizumab-based combination therapy for non–small cell lung cancer (NSCLC)

M. Gutierrez, Wei-Sen Lam, M. Hellmann, M. Gubens, C. Aggarwal, Daniel Shao Weng Tan, E. Felip, Joannellyn Chiu, Jong-Seok Lee, J. Yang, E. Garon, G. Finocchiaro, M. Ahn, A. Luft, G. Landers, A. Basso, Hua Ma, J. Kobie, J. Palcza, R. Cristescu, L. Fong, A. Snyder, Jianda Yuan, R. Herbst · 2021 · Journal for ImmunoTherapy of Cancer · DOI

Full title: 457 KEYNOTE-495/KeyImPaCT: interim analysis of a randomized, biomarker-directed, phase 2 trial of pembrolizumab-based combination therapy for non–small cell lung cancer (NSCLC)

Authors: M. Gutierrez, Wei-Sen Lam, M. Hellmann, M. Gubens, C. Aggarwal, Daniel Shao Weng Tan, E. Felip, Joannellyn Chiu, Jong-Seok Lee, J. Yang, E. Garon, G. Finocchiaro, M. Ahn, A. Luft, G. Landers, A. Basso, Hua Ma, J. Kobie, J. Palcza, R. Cristescu, L. Fong, A. Snyder, Jianda Yuan, R. Herbst

Year: 2021

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2021-sitc2021.457

Paper Safety of Nivolumab plus Low-Dose Ipilimumab in Previously Treated Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer

Morse, Michael A., Overman, Michael J., Hartman, Leighanne, Khoukaz, Taline, Brutcher, Edith, Lenz, Heinz‐Josef, Atasoy, Ajlan, Shangguan, Tong, Zhao, Huanyu, El‐Rayes, Bassel F. · 2019 · The Oncologist · DOI

Full title: Safety of Nivolumab plus Low-Dose Ipilimumab in Previously Treated Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer

Authors: Morse, Michael A., Overman, Michael J., Hartman, Leighanne, Khoukaz, Taline, Brutcher, Edith, Lenz, Heinz‐Josef, Atasoy, Ajlan, Shangguan, Tong, Zhao, Huanyu, El‐Rayes, Bassel F.

Year: 2019

Venue: The Oncologist

DOI: https://doi.org/10.1634/theoncologist.2019-0129

Paper Unravelling T cell exhaustion through co-inhibitory receptors and its transformative role in cancer immunotherapy.

Xiang, Simin, Li, Sen, Xu, Junfen · 2025 · Clinical and translational medicine · DOI

Full title: Unravelling T cell exhaustion through co-inhibitory receptors and its transformative role in cancer immunotherapy.

Authors: Xiang, Simin, Li, Sen, Xu, Junfen

Year: 2025

Venue: Clinical and translational medicine

DOI: https://doi.org/10.1002/ctm2.70345

Paper Combined PD-L1 and TIM-3 blockade improves the expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy

Lak, Shirin, Janelle, Valérie, Djedid, Anissa, Boudreau, Gabrielle, Brasey, Ann, Lisi, Véronique, Carli, Cédric, Busque, Lambert, Lavallée, Vincent‐Philippe, Delisle, Jean‐Sébastien · 2021 · DOI

Full title: Combined PD-L1 and TIM-3 blockade improves the expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy

Authors: Lak, Shirin, Janelle, Valérie, Djedid, Anissa, Boudreau, Gabrielle, Brasey, Ann, Lisi, Véronique, Carli, Cédric, Busque, Lambert, Lavallée, Vincent‐Philippe, Delisle, Jean‐Sébastien

Year: 2021

DOI: https://doi.org/10.1101/2021.08.30.21262835

Paper TIGIT: a novel immunotherapy target moving from bench to bedside.

Solomon, Benjamin L, Garrido-Laguna, Ignacio · 2018 · Cancer immunology, immunotherapy : CII · DOI

Full title: TIGIT: a novel immunotherapy target moving from bench to bedside.

Authors: Solomon, Benjamin L, Garrido-Laguna, Ignacio

Year: 2018

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-018-2246-5

Paper Modeling tumour heterogeneity of PD-L1 expression in tumour progression and adaptive therapy.

Ma, Shizhao, Lei, Jinzhi, Lai, Xiulan · 2023 · Journal of mathematical biology · DOI

Full title: Modeling tumour heterogeneity of PD-L1 expression in tumour progression and adaptive therapy.

Authors: Ma, Shizhao, Lei, Jinzhi, Lai, Xiulan

Year: 2023

Venue: Journal of mathematical biology

DOI: https://doi.org/10.1007/s00285-023-01872-1

Paper Non-small cell lung cancer: current treatment and future advances

Zappa, Cecilia, Mousa, Shaker A. · 2016 · Translational Lung Cancer Research · DOI

Full title: Non-small cell lung cancer: current treatment and future advances

Authors: Zappa, Cecilia, Mousa, Shaker A.

Year: 2016

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2016.06.07

Paper A2AR as a key target for immune microenvironment remodeling in prostate cancer.

Lanzhi Yan, Ze Yang, Xiaojing Zhao, Yong Chen, Zhe Wang · 2026 · Translational Oncology · DOI

Full title: A2AR as a key target for immune microenvironment remodeling in prostate cancer.

Authors: Lanzhi Yan, Ze Yang, Xiaojing Zhao, Yong Chen, Zhe Wang

Year: 2026

Venue: Translational Oncology

DOI: https://doi.org/10.1016/j.tranon.2026.102720

Paper Distinct immunologic changes in vivo following combination versus individual PD-1 or CTLA-4 checkpoint blockade in human cancer

Dhodapkar, Kavita M., Verma, Rakesh, Sznol, Mario, Boddupalli, Chandra Sekhar, Gettinger, Scott, Kluger, Harriet M., Dhodapkar, Madhav V., Das, Rituparna · 2014 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Distinct immunologic changes in vivo following combination versus individual PD-1 or CTLA-4 checkpoint blockade in human cancer

Authors: Dhodapkar, Kavita M., Verma, Rakesh, Sznol, Mario, Boddupalli, Chandra Sekhar, Gettinger, Scott, Kluger, Harriet M., Dhodapkar, Madhav V., Das, Rituparna

Year: 2014

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/2051-1426-2-s3-o7

Paper Treatment of atypical pulmonary carcinoid with combination ipilimumab and nivolumab.

Nestor, Jacquelyn, Barnaby, Keara, Esposito, Michael, Seetharamu, Nagashree · 2019 · BMJ case reports · DOI

Full title: Treatment of atypical pulmonary carcinoid with combination ipilimumab and nivolumab.

Authors: Nestor, Jacquelyn, Barnaby, Keara, Esposito, Michael, Seetharamu, Nagashree

Year: 2019

Venue: BMJ case reports

DOI: https://doi.org/10.1136/bcr-2019-231029

Paper Discrepant CD3+ TILs in PD-L1-Negative NSCLC: Favorable Outcome in an Elderly Patient Treated With Nivolumab, Ipilimumab, and Chemotherapy.

Sekiya, Mataichi, Nakatsugawa, Munehide, Koyama, Nobuyuki, Kajiwara, Naohiro, Aoki, Takuya · 2026 · The American journal of case reports · DOI

Full title: Discrepant CD3+ TILs in PD-L1-Negative NSCLC: Favorable Outcome in an Elderly Patient Treated With Nivolumab, Ipilimumab, and Chemotherapy.

Authors: Sekiya, Mataichi, Nakatsugawa, Munehide, Koyama, Nobuyuki, Kajiwara, Naohiro, Aoki, Takuya

Year: 2026

Venue: The American journal of case reports

DOI: https://doi.org/10.12659/AJCR.951075

Paper Thyroid Immune-Related Adverse Events in Patients with Cancer Treated with anti-PD1/anti-CTLA4 Immune Checkpoint Inhibitor Combination: Clinical Course and Outcomes.

Lui, David Tak Wai, Lee, Chi Ho, Tang, Vikki, Fong, Carol Ho Yi, Lee, Alan Chun Hong, Chiu, Joanne Wing Yan, Leung, Roland Ching Yu, Kwok, Gerry Gin Wai, Li, Bryan Cho Wing, Cheung, Tan To, Woo, Yu Cho, Lam, Karen Siu Ling, Yau, Thomas · 2021 · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · DOI

Full title: Thyroid Immune-Related Adverse Events in Patients with Cancer Treated with anti-PD1/anti-CTLA4 Immune Checkpoint Inhibitor Combination: Clinical Course and Outcomes.

Authors: Lui, David Tak Wai, Lee, Chi Ho, Tang, Vikki, Fong, Carol Ho Yi, Lee, Alan Chun Hong, Chiu, Joanne Wing Yan, Leung, Roland Ching Yu, Kwok, Gerry Gin Wai, Li, Bryan Cho Wing, Cheung, Tan To, Woo, Yu Cho, Lam, Karen Siu Ling, Yau, Thomas

Year: 2021

Venue: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

DOI: https://doi.org/10.1016/j.eprac.2021.01.017

Paper [Personalized modulation of tumor microimmune microenvironment for the development of effective combination immunotherapy].

Kawakami, Yutaka · 2018 · [Rinsho ketsueki] The Japanese journal of clinical hematology · DOI

Full title: [Personalized modulation of tumor microimmune microenvironment for the development of effective combination immunotherapy].

Authors: Kawakami, Yutaka

Year: 2018

Venue: [Rinsho ketsueki] The Japanese journal of clinical hematology

DOI: https://doi.org/10.11406/rinketsu.59.939

Paper Regulatory T cells in cancer immunotherapy

Tanaka, Atsushi, Sakaguchi, Shimon · 2016 · Cell Research · DOI

Full title: Regulatory T cells in cancer immunotherapy

Authors: Tanaka, Atsushi, Sakaguchi, Shimon

Year: 2016

Venue: Cell Research

DOI: https://doi.org/10.1038/cr.2016.151

Paper Immunotherapy for head and neck cancer: Present and future.

Fasano, Morena, Corte, Carminia Maria Della, Liello, Raimondo Di, Viscardi, Giuseppe, Sparano, Francesca, Iacovino, Maria Lucia, Paragliola, Fernando, Piccolo, Antonio, Napolitano, Stefania, Martini, Giulia, Morgillo, Floriana, Cappabianca, Salvatore, Ciardiello, Fortunato · 2022 · Critical reviews in oncology/hematology · DOI

Full title: Immunotherapy for head and neck cancer: Present and future.

Authors: Fasano, Morena, Corte, Carminia Maria Della, Liello, Raimondo Di, Viscardi, Giuseppe, Sparano, Francesca, Iacovino, Maria Lucia, Paragliola, Fernando, Piccolo, Antonio, Napolitano, Stefania, Martini, Giulia, Morgillo, Floriana, Cappabianca, Salvatore, Ciardiello, Fortunato

Year: 2022

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2022.103679

Paper Health Care Resource Utilization and Costs in First-Line Treatments for Patients with Metastatic Melanoma in the United States.

A. Klink, B. Chmielowski, B. Feinberg, S. Ahsan, D. Nero, Frank X Liu · 2019 · Journal of Managed Care & Specialty Pharmacy · DOI

Full title: Health Care Resource Utilization and Costs in First-Line Treatments for Patients with Metastatic Melanoma in the United States.

Authors: A. Klink, B. Chmielowski, B. Feinberg, S. Ahsan, D. Nero, Frank X Liu

Year: 2019

Venue: Journal of Managed Care & Specialty Pharmacy

DOI: https://doi.org/10.18553/jmcp.2019.18442

Paper The efficacy and safety of PD-1/PD-L1 inhibitors in breast cancer: a systematic review and meta-analysis.

Xiao, Bo-Ya, Lin, Guo-He, Zhao, Yan-Xia, Wang, Bi-Cheng · 2020 · Translational cancer research · DOI

Full title: The efficacy and safety of PD-1/PD-L1 inhibitors in breast cancer: a systematic review and meta-analysis.

Authors: Xiao, Bo-Ya, Lin, Guo-He, Zhao, Yan-Xia, Wang, Bi-Cheng

Year: 2020

Venue: Translational cancer research

DOI: https://doi.org/10.21037/tcr-19-3020

Paper Clofazimine Reduces Side Effects from Dual Immune Checkpoint Blockade

· 2024 · Cancer Discovery · DOI

Full title: Clofazimine Reduces Side Effects from Dual Immune Checkpoint Blockade

Year: 2024

Venue: Cancer Discovery

DOI: https://doi.org/10.1158/2159-8290.cd-rw2024-048

Paper Targeting immune checkpoints: releasing the restraints on anti-tumor immunity for patients with melanoma.

Postow, Michael A, Harding, James, Wolchok, Jedd D · 2012 · Cancer journal (Sudbury, Mass.)

Full title: Targeting immune checkpoints: releasing the restraints on anti-tumor immunity for patients with melanoma.

Authors: Postow, Michael A, Harding, James, Wolchok, Jedd D

Year: 2012

Venue: Cancer journal (Sudbury, Mass.)

Paper European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

Stratigos, Alexander, Garbe, Claus, Dessinioti, Clio, Lebbé, Célèste, Bataille, Véronique, Bastholt, Lars, Dréno, Brigitte, Fargnoli, Maria Concetta, Forsea, Ana‐Maria, Frenard, Cecille, Harwood, Catherine, Hauschild, Axel, Höeller, Christoph, Sekulović, Lidija Kandolf, Kaufmann, Roland, Kelleners-Smeets, Nicole W.J., Malvehy, Josep, Mármol, V. del, Middleton, Mark R., Moreno‐Ramírez, D., Pellecani, Giovanni, Peris, Ketty, Saïag, Philippe, Everdingen, M.H.J. van den Beuken-van, Vieira, Ricardo, Zalaudek, Iris, Eggermont, Alexander M.M., Grob, Jean-Jacques · 2020 · European Journal of Cancer · DOI

Full title: European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

Authors: Stratigos, Alexander, Garbe, Claus, Dessinioti, Clio, Lebbé, Célèste, Bataille, Véronique, Bastholt, Lars, Dréno, Brigitte, Fargnoli, Maria Concetta, Forsea, Ana‐Maria, Frenard, Cecille, Harwood, Catherine, Hauschild, Axel, Höeller, Christoph, Sekulović, Lidija Kandolf, Kaufmann, Roland, Kelleners-Smeets, Nicole W.J., Malvehy, Josep, Mármol, V. del, Middleton, Mark R., Moreno‐Ramírez, D., Pellecani, Giovanni, Peris, Ketty, Saïag, Philippe, Everdingen, M.H.J. van den Beuken-van, Vieira, Ricardo, Zalaudek, Iris, Eggermont, Alexander M.M., Grob, Jean-Jacques

Year: 2020

Venue: European Journal of Cancer

DOI: https://doi.org/10.1016/j.ejca.2020.01.008

Paper Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity

Ager, Casey R., Reilley, Matthew J., Nicholas, Courtney, Bartkowiak, Todd, Jaiswal, Ashvin R., Curran, Michael A. · 2017 · Cancer Immunology Research · DOI

Full title: Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity

Authors: Ager, Casey R., Reilley, Matthew J., Nicholas, Courtney, Bartkowiak, Todd, Jaiswal, Ashvin R., Curran, Michael A.

Year: 2017

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-17-0049

Paper Skin toxicity associated with immune checkpoint inhibitors based on the FDA adverse event reporting system 2011 - 2023 data.

Qiu, Xiao-Yan, Fu, Zhang-Yong, Wu, Ai-Feng · 2025 · International journal of clinical pharmacology and therapeutics · DOI

Full title: Skin toxicity associated with immune checkpoint inhibitors based on the FDA adverse event reporting system 2011 - 2023 data.

Authors: Qiu, Xiao-Yan, Fu, Zhang-Yong, Wu, Ai-Feng

Year: 2025

Venue: International journal of clinical pharmacology and therapeutics

DOI: https://doi.org/10.5414/CP204739

Paper Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging concepts.

Fumet, Jean-David, Truntzer, Caroline, Yarchoan, Mark, Ghiringhelli, Francois · 2020 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging concepts.

Authors: Fumet, Jean-David, Truntzer, Caroline, Yarchoan, Mark, Ghiringhelli, Francois

Year: 2020

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2020.02.038

Paper Breast Cancer Vaccines: A Review of Emerging Opportunities and Persistent Challenges.

Sheela, I Jeya, Jeya Ranchani, A Amala, Murali, Aravindh, Premkumar, H · 2026 · Clinical breast cancer · DOI

Full title: Breast Cancer Vaccines: A Review of Emerging Opportunities and Persistent Challenges.

Authors: Sheela, I Jeya, Jeya Ranchani, A Amala, Murali, Aravindh, Premkumar, H

Year: 2026

Venue: Clinical breast cancer

DOI: https://doi.org/10.1016/j.clbc.2026.01.004

Paper Clinical Outcomes in Patients With Metastatic Lung Cancer Treated With PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy.

Hwang, William L, Niemierko, Andrzej, Hwang, Katie L, Hubbeling, Harper, Schapira, Emily, Gainor, Justin F, Keane, Florence K · 2018 · JAMA oncology · DOI

Full title: Clinical Outcomes in Patients With Metastatic Lung Cancer Treated With PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy.

Authors: Hwang, William L, Niemierko, Andrzej, Hwang, Katie L, Hubbeling, Harper, Schapira, Emily, Gainor, Justin F, Keane, Florence K

Year: 2018

Venue: JAMA oncology

DOI: https://doi.org/10.1001/jamaoncol.2017.3808

Paper Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies.

Dai, Min, Yip, Yuen Yee, Hellstrom, Ingegerd, Hellstrom, Karl Erik · 2015 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies.

Authors: Dai, Min, Yip, Yuen Yee, Hellstrom, Ingegerd, Hellstrom, Karl Erik

Year: 2015

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-14-1339

Paper Combination immunotherapy for cancer.

Fearon, Douglas · 2016 · The Journal of experimental medicine · DOI

Full title: Combination immunotherapy for cancer.

Authors: Fearon, Douglas

Year: 2016

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.2137insight2

Paper Exploring the application of PD-1/PD-L1 inhibitors for ovarian cancer.

Miao, Xinyu, Wang, Zhenpeng, Liu, Dongzhen, Ji, Shuyu, Li, Jiajia, Zhang, Songling · 2026 · Cancer treatment and research communications · DOI

Full title: Exploring the application of PD-1/PD-L1 inhibitors for ovarian cancer.

Authors: Miao, Xinyu, Wang, Zhenpeng, Liu, Dongzhen, Ji, Shuyu, Li, Jiajia, Zhang, Songling

Year: 2026

Venue: Cancer treatment and research communications

DOI: https://doi.org/10.1016/j.ctarc.2025.101053

Paper Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Xu-Monette, Ziju Y., Xiao, Min, Au, Qingyan, Padmanabhan, Raghav, Xu, Bing, Hoe, Nicholas, Rodríguez, Sandra, Torres, Raúl, Manyam, Ganiraju C., Visco, Carlo, Miao, Yi, Tan, Xiaohong, Zhang, Hongwei, Tzankov, Alexandar, Wang, Jing, Dybkær, Karen, Tam, Wayne, You, Hua, Bhagat, Govind, Hsi, Eric D., Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael, Piris, Miguel Á., Krieken, J. Han van, Winter, Jane N., Westin, Jason R., Pham, Lan V., Medeiros, L. Jeffrey, Rassidakis, George Z., Li, Yong, Freeman, Gordon J., Young, Ken H. · 2019 · Cancer Immunology Research · DOI

Full title: Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL

Authors: Xu-Monette, Ziju Y., Xiao, Min, Au, Qingyan, Padmanabhan, Raghav, Xu, Bing, Hoe, Nicholas, Rodríguez, Sandra, Torres, Raúl, Manyam, Ganiraju C., Visco, Carlo, Miao, Yi, Tan, Xiaohong, Zhang, Hongwei, Tzankov, Alexandar, Wang, Jing, Dybkær, Karen, Tam, Wayne, You, Hua, Bhagat, Govind, Hsi, Eric D., Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael, Piris, Miguel Á., Krieken, J. Han van, Winter, Jane N., Westin, Jason R., Pham, Lan V., Medeiros, L. Jeffrey, Rassidakis, George Z., Li, Yong, Freeman, Gordon J., Young, Ken H.

Year: 2019

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-18-0439

Paper A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1.

Li, Ting, Wu, Bao-Liang, Yu, Cai-Long, Jin, Liang-Yan · 2026 · Clinical case reports · DOI

Full title: A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1.

Authors: Li, Ting, Wu, Bao-Liang, Yu, Cai-Long, Jin, Liang-Yan

Year: 2026

Venue: Clinical case reports

DOI: https://doi.org/10.1002/ccr3.72025

Paper Enhancing cancer care with improved checkpoint inhibitors: a focus on PD-1/PD-L1.

A S, Vickram, Shofia, Saghya Infant, Saravanan, A, Sivakumar, Vidhya Lakshmi, Thamarai, Packiyam, Sivasubramanian, Manikandan, Chopra, Shivani, Chopra, Hitesh · 2024 · EXCLI journal · DOI

Full title: Enhancing cancer care with improved checkpoint inhibitors: a focus on PD-1/PD-L1.

Authors: A S, Vickram, Shofia, Saghya Infant, Saravanan, A, Sivakumar, Vidhya Lakshmi, Thamarai, Packiyam, Sivasubramanian, Manikandan, Chopra, Shivani, Chopra, Hitesh

Year: 2024

Venue: EXCLI journal

DOI: https://doi.org/10.17179/excli2024-7783

Paper A narrative review of management of muscle-invasive bladder cancer perioperative period: will continuous and combined treatment be the new trend?

Lan, Tianhang, Ran, Shengming, Gao, Mingchao, Li, Wenjie, He, Wang · 2024 · Translational andrology and urology · DOI

Full title: A narrative review of management of muscle-invasive bladder cancer perioperative period: will continuous and combined treatment be the new trend?

Authors: Lan, Tianhang, Ran, Shengming, Gao, Mingchao, Li, Wenjie, He, Wang

Year: 2024

Venue: Translational andrology and urology

DOI: https://doi.org/10.21037/tau-23-494

Paper Timing of immunotherapy-induced pneumonitis in patients with primary lung malignancy.

M. Winter, M. Gilani, Manasa Anipindi, Tejaswi Venigalla, Shriya Doreswamy · 2023 · Journal of Clinical Oncology · DOI

Full title: Timing of immunotherapy-induced pneumonitis in patients with primary lung malignancy.

Authors: M. Winter, M. Gilani, Manasa Anipindi, Tejaswi Venigalla, Shriya Doreswamy

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.16_suppl.2647

Paper Phase I study on neoadjuvant combination immunotherapy with mogamulizumab and nivolumab for solid tumors

Jinushi, Koichi, Saito, Takuro, Kurose, Koji, Suzuki, Susumu, Kojima, Takashi, Takahara, Taishi, Makino, Tomoki, Ogawa, Tetsuya, Nishikawa, Hiroyoshi, Kakimi, Kazuhiro, Iida, Shinsuke, Nakajima, Jun, Doki, Yuichiro, Oka, Mikio, Ueda, Ryuzo, Wada, Hisashi · 2025 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Phase I study on neoadjuvant combination immunotherapy with mogamulizumab and nivolumab for solid tumors

Authors: Jinushi, Koichi, Saito, Takuro, Kurose, Koji, Suzuki, Susumu, Kojima, Takashi, Takahara, Taishi, Makino, Tomoki, Ogawa, Tetsuya, Nishikawa, Hiroyoshi, Kakimi, Kazuhiro, Iida, Shinsuke, Nakajima, Jun, Doki, Yuichiro, Oka, Mikio, Ueda, Ryuzo, Wada, Hisashi

Year: 2025

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2024-010634

Paper Genomic and transcriptional changes in IFNγ pathway genes are putative biomarkers of response to ipilimumab immunotherapy in melanoma patients.

Hargadon, Kristian M, Győrffy, Balázs, McGee, Taylor J · 2020 · Expert review of clinical immunology · DOI

Full title: Genomic and transcriptional changes in IFNγ pathway genes are putative biomarkers of response to ipilimumab immunotherapy in melanoma patients.

Authors: Hargadon, Kristian M, Győrffy, Balázs, McGee, Taylor J

Year: 2020

Venue: Expert review of clinical immunology

DOI: https://doi.org/10.1080/1744666X.2021.1847644

Paper Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers.

Galliverti, Gabriele, Wullschleger, Stephan, Tichet, Mélanie, Murugan, Dhaarini, Zangger, Nadine, Horton, Wesley, Korman, Alan J, Coussens, Lisa M, Swartz, Melody A, Hanahan, Douglas · 2020 · Cancer immunology research · DOI

Full title: Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers.

Authors: Galliverti, Gabriele, Wullschleger, Stephan, Tichet, Mélanie, Murugan, Dhaarini, Zangger, Nadine, Horton, Wesley, Korman, Alan J, Coussens, Lisa M, Swartz, Melody A, Hanahan, Douglas

Year: 2020

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-19-0315

Paper Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.

Soldatos, Theodoros G, Dimitrakopoulou-Strauss, Antonia, Larribere, Lionel, Hassel, Jessica C, Sachpekidis, Christos · 2018 · Diagnostics (Basel, Switzerland) · DOI

Full title: Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.

Authors: Soldatos, Theodoros G, Dimitrakopoulou-Strauss, Antonia, Larribere, Lionel, Hassel, Jessica C, Sachpekidis, Christos

Year: 2018

Venue: Diagnostics (Basel, Switzerland)

DOI: https://doi.org/10.3390/diagnostics8040076

Paper The current status of checkpoint inhibitors in metastatic bladder cancer.

Fahmy, Omar, Khairul-Asri, Mohd Ghani, Stenzl, Arnulf, Gakis, Georgios · 2016 · Clinical & experimental metastasis · DOI

Full title: The current status of checkpoint inhibitors in metastatic bladder cancer.

Authors: Fahmy, Omar, Khairul-Asri, Mohd Ghani, Stenzl, Arnulf, Gakis, Georgios

Year: 2016

Venue: Clinical & experimental metastasis

DOI: https://doi.org/10.1007/s10585-016-9807-9

Paper Abstract C064: Tumor Ecosystem and Microbiome Features Associated with Efficacy from Avelumab-based Multimodal Therapy in a Phase III Randomized Trial

T. Alban, N. Riaz, Robert I. Haddad, Michelle Saul, V. Makarov, Yingjie Zhu, E. Cohen, R. Ferris, Peter Chang, J. Lin, Amanda Pyrri, P. Parthasarathy, A. Novaj, M. Gawali, Jennifer S Ko, Phineas Hamilton, Natalie Silver, I. Jurić, Daniel Chawla, Ana Gradissimo, D. McGrail, C. Davis, N. Lee, T. Chan · 2026 · Cancer immunology research · DOI

Full title: Abstract C064: Tumor Ecosystem and Microbiome Features Associated with Efficacy from Avelumab-based Multimodal Therapy in a Phase III Randomized Trial

Authors: T. Alban, N. Riaz, Robert I. Haddad, Michelle Saul, V. Makarov, Yingjie Zhu, E. Cohen, R. Ferris, Peter Chang, J. Lin, Amanda Pyrri, P. Parthasarathy, A. Novaj, M. Gawali, Jennifer S Ko, Phineas Hamilton, Natalie Silver, I. Jurić, Daniel Chawla, Ana Gradissimo, D. McGrail, C. Davis, N. Lee, T. Chan

Year: 2026

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6074.io2026-c064

Paper Management of Advanced Pleural Mesothelioma-At the Crossroads.

Nowak, Anna K, Jackson, Alannah, Sidhu, Calvin · 2022 · JCO oncology practice · DOI

Full title: Management of Advanced Pleural Mesothelioma-At the Crossroads.

Authors: Nowak, Anna K, Jackson, Alannah, Sidhu, Calvin

Year: 2022

Venue: JCO oncology practice

DOI: https://doi.org/10.1200/OP.21.00426

Paper Genomic Features of Response to Combination Immunotherapy in Lung Cancer.

Früh, Martin, Peters, Solange · 2018 · Cancer cell · DOI

Full title: Genomic Features of Response to Combination Immunotherapy in Lung Cancer.

Authors: Früh, Martin, Peters, Solange

Year: 2018

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2018.04.005

Paper Fulminant Myocarditis with Combination Immune Checkpoint Blockade

Johnson, Douglas B., Balko, Justin M., Compton, Margaret, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R., Bloomer, Tyler, Becker, Jason R., Slosky, David, Phillips, Elizabeth J., Pilkinton, Mark A., Craig-Owens, Laura Deeanne, Kola, Nina, Plautz, Gregory E., Reshef, Daniel S., Deutsch, Jonathan S., Deering, Raquel P., Olenchock, Benjamin A., Lichtman, Andrew H., Roden, Dan M., Seidman, Christine E., Koralnik, Igor J., Seidman, Jonathan G., Hoffman, Robert, Taube, Janis M., Díaz, Luis A., Anders, Robert A., Sosman, Jeffrey A., Moslehi, Javid J. · 2016 · New England Journal of Medicine · DOI

Full title: Fulminant Myocarditis with Combination Immune Checkpoint Blockade

Authors: Johnson, Douglas B., Balko, Justin M., Compton, Margaret, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R., Bloomer, Tyler, Becker, Jason R., Slosky, David, Phillips, Elizabeth J., Pilkinton, Mark A., Craig-Owens, Laura Deeanne, Kola, Nina, Plautz, Gregory E., Reshef, Daniel S., Deutsch, Jonathan S., Deering, Raquel P., Olenchock, Benjamin A., Lichtman, Andrew H., Roden, Dan M., Seidman, Christine E., Koralnik, Igor J., Seidman, Jonathan G., Hoffman, Robert, Taube, Janis M., Díaz, Luis A., Anders, Robert A., Sosman, Jeffrey A., Moslehi, Javid J.

Year: 2016

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1609214

Paper Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy.

Fan, Xiaozhou, Quezada, Sergio A, Sepulveda, Manuel A, Sharma, Padmanee, Allison, James P · 2014 · The Journal of experimental medicine · DOI

Full title: Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy.

Authors: Fan, Xiaozhou, Quezada, Sergio A, Sepulveda, Manuel A, Sharma, Padmanee, Allison, James P

Year: 2014

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20130590

Paper Abstract OT2-08-02: SOLTI-1907 ATREZZO: Targeting hormonal receptor negative (HR-) or PAM50 non-luminal disease with atezolizumab in combination with trastuzumab and vinorelbine in HER2-positive metastatic breast cancer (MBC)

E. Ciruelos, A. Perelló, S. González-Santiago, Ana Lopez, F. J. S. Bofill, C. Albacar, J. Cejalvo, S. Escrivá-de-Romaní, I. Blancas, S. Pernas, O. Martínez-Sáez, J. Cruz, José Ponce, S. Servitja, M. Perez-Lopez, J. Guerra, E. Sanfeliu, C. Rodríguez, G. Villacampa, L. Villanueva, P. Tolosa, T. Pascual, A. Prat · 2023 · Cancer Research · DOI

Full title: Abstract OT2-08-02: SOLTI-1907 ATREZZO: Targeting hormonal receptor negative (HR-) or PAM50 non-luminal disease with atezolizumab in combination with trastuzumab and vinorelbine in HER2-positive metastatic breast cancer (MBC)

Authors: E. Ciruelos, A. Perelló, S. González-Santiago, Ana Lopez, F. J. S. Bofill, C. Albacar, J. Cejalvo, S. Escrivá-de-Romaní, I. Blancas, S. Pernas, O. Martínez-Sáez, J. Cruz, José Ponce, S. Servitja, M. Perez-Lopez, J. Guerra, E. Sanfeliu, C. Rodríguez, G. Villacampa, L. Villanueva, P. Tolosa, T. Pascual, A. Prat

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.sabcs22-ot2-08-02

Paper [Immunotherapy for gastroenterological cancer].

Narita, Yukiya, Muro, Kei · 2017 · Nihon rinsho. Japanese journal of clinical medicine

Full title: [Immunotherapy for gastroenterological cancer].

Authors: Narita, Yukiya, Muro, Kei

Year: 2017

Venue: Nihon rinsho. Japanese journal of clinical medicine

Paper Immune-related adverse events in the gastrointestinal tract: diagnostic utility of upper gastrointestinal biopsies.

Zhang, M Lisa, Neyaz, Azfar, Patil, Deepa, Chen, Jonathan, Dougan, Michael, Deshpande, Vikram · 2020 · Histopathology · DOI

Full title: Immune-related adverse events in the gastrointestinal tract: diagnostic utility of upper gastrointestinal biopsies.

Authors: Zhang, M Lisa, Neyaz, Azfar, Patil, Deepa, Chen, Jonathan, Dougan, Michael, Deshpande, Vikram

Year: 2020

Venue: Histopathology

DOI: https://doi.org/10.1111/his.13963

Paper Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy.

Kim, Peter S, Jochems, Caroline, Grenga, Italia, Donahue, Renee N, Tsang, Kwong Y, Gulley, James L, Schlom, Jeffrey, Farsaci, Benedetto · 2014 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy.

Authors: Kim, Peter S, Jochems, Caroline, Grenga, Italia, Donahue, Renee N, Tsang, Kwong Y, Gulley, James L, Schlom, Jeffrey, Farsaci, Benedetto

Year: 2014

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.1301369

Paper Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes

Esagian, Stepan M., Khaki, Ali Raza, Diamantopoulos, Leonidas Nikolaos, Carril-Ajuria, Lucía, Castellano, Daniel, Kouchkovsky, Ivan de, Park, Joseph J., Alva, Ajjai, Bilen, Mehmet Asım, Stewart, Tyler F., McKay, Rana R., Santos, Víctor Sacristán, Agarwal, Neeraj, Jain, Jayanshu, Zakharia, Yousef, Morales‐Barrera, Rafael, Devitt, Michael, Nelson, Ariel Ann, Hoimes, Christopher, Shreck, Evan, Gartrell, Benjamin A., Sankin, Alex, Tripathi, Abhishek, Zakopoulou, Roubini, Bamias, Aristotelis, Rodríguez‐Vida, Alejo, Drakaki, Alexandra, Liu, Sandy, Kumar, Vivek, Lythgoe, Mark P., Pinato, David J., Murgić, Jure, Fröbe, Ana, Joshi, Monika, Velho, Pedro Isaacsson, Hahn, Noah M., Buznego, Lucía Alonso, Durán, Ignacio, Moses, Marcus W., Barata, Pedro C., Galsky, Matthew D., Sonpavde, Guru, Yu, Evan Y., Msaouel, Pavlos, Koshkin, Vadim S., Grivas, Petros · 2021 · British Journal of Urology · DOI

Full title: Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes

Authors: Esagian, Stepan M., Khaki, Ali Raza, Diamantopoulos, Leonidas Nikolaos, Carril-Ajuria, Lucía, Castellano, Daniel, Kouchkovsky, Ivan de, Park, Joseph J., Alva, Ajjai, Bilen, Mehmet Asım, Stewart, Tyler F., McKay, Rana R., Santos, Víctor Sacristán, Agarwal, Neeraj, Jain, Jayanshu, Zakharia, Yousef, Morales‐Barrera, Rafael, Devitt, Michael, Nelson, Ariel Ann, Hoimes, Christopher, Shreck, Evan, Gartrell, Benjamin A., Sankin, Alex, Tripathi, Abhishek, Zakopoulou, Roubini, Bamias, Aristotelis, Rodríguez‐Vida, Alejo, Drakaki, Alexandra, Liu, Sandy, Kumar, Vivek, Lythgoe, Mark P., Pinato, David J., Murgić, Jure, Fröbe, Ana, Joshi, Monika, Velho, Pedro Isaacsson, Hahn, Noah M., Buznego, Lucía Alonso, Durán, Ignacio, Moses, Marcus W., Barata, Pedro C., Galsky, Matthew D., Sonpavde, Guru, Yu, Evan Y., Msaouel, Pavlos, Koshkin, Vadim S., Grivas, Petros

Year: 2021

Venue: British Journal of Urology

DOI: https://doi.org/10.1111/bju.15324

Paper DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy.

Gilmore, Elaine, McCabe, Nuala, Kennedy, Richard D, Parkes, Eileen E · 2019 · Journal of oncology · DOI

Full title: DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy.

Authors: Gilmore, Elaine, McCabe, Nuala, Kennedy, Richard D, Parkes, Eileen E

Year: 2019

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2019/4325105

Paper Combination Immunotherapy in Non-small Cell Lung Cancer.

Marmarelis, Melina E, Aggarwal, Charu · 2018 · Current oncology reports · DOI

Full title: Combination Immunotherapy in Non-small Cell Lung Cancer.

Authors: Marmarelis, Melina E, Aggarwal, Charu

Year: 2018

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-018-0697-7

Paper Role of CTLA Inhibition in Management of Non-Small Cell Lung Cancer.

Kerrigan, Kathleen, Puri, Sonam · 2022 · Current oncology reports · DOI

Full title: Role of CTLA Inhibition in Management of Non-Small Cell Lung Cancer.

Authors: Kerrigan, Kathleen, Puri, Sonam

Year: 2022

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-021-01164-1

Paper Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in a patient with advanced pretreated hepatocellular carcinoma.

Joerger, Markus, Güller, Ulrich, Bastian, Sara, Driessen, Christoph, von Moos, Roger · 2019 · Journal of gastrointestinal oncology · DOI

Full title: Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in a patient with advanced pretreated hepatocellular carcinoma.

Authors: Joerger, Markus, Güller, Ulrich, Bastian, Sara, Driessen, Christoph, von Moos, Roger

Year: 2019

Venue: Journal of gastrointestinal oncology

DOI: https://doi.org/10.21037/jgo.2018.11.04

Paper First case report of immune checkpoint inhibitor-related pneumonitis triggered by bispecific antibody (anti-PD-L1 and anti-CTLA-4) in a patient with non-small cell lung cancer: case report.

Sun, Haishuang, Liu, Yu, Chen, Zihong, Fang, Wenfeng, Zhang, Li, Zhang, Yaxiong · 2025 · Translational lung cancer research · DOI

Full title: First case report of immune checkpoint inhibitor-related pneumonitis triggered by bispecific antibody (anti-PD-L1 and anti-CTLA-4) in a patient with non-small cell lung cancer: case report.

Authors: Sun, Haishuang, Liu, Yu, Chen, Zihong, Fang, Wenfeng, Zhang, Li, Zhang, Yaxiong

Year: 2025

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-2025-479

Paper Application of a patient-centered reverse translational systems-based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors.

Kim, Sarah, Lahu, Gezim, Vakilynejad, Majid, Soldatos, Theodoros G, Jackson, David B, Lesko, Lawrence J, Trame, Mirjam N · 2022 · Clinical and translational science · DOI

Full title: Application of a patient-centered reverse translational systems-based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors.

Authors: Kim, Sarah, Lahu, Gezim, Vakilynejad, Majid, Soldatos, Theodoros G, Jackson, David B, Lesko, Lawrence J, Trame, Mirjam N

Year: 2022

Venue: Clinical and translational science

DOI: https://doi.org/10.1111/cts.13254

Paper LCCC 1525: Combination immunotherapy with cyclophosphamide plus pembrolizumab in patients with advanced triple negative breast cancer (TNBC).

Vincent, Benjamin G., Moore, Dominic T., Moore, Susan, Kaltman, Rebecca, Puhalla, Shannon, Gudena, Vinay, Carey, Lisa A., Dees, Elizabeth Claire, Muss, Hyman B., Reeder‐Hayes, Katherine E., Jolly, Trevor A., Serody, Jonathan S., Anders, Carey K. · 2017 · Journal of Clinical Oncology · DOI

Full title: LCCC 1525: Combination immunotherapy with cyclophosphamide plus pembrolizumab in patients with advanced triple negative breast cancer (TNBC).

Authors: Vincent, Benjamin G., Moore, Dominic T., Moore, Susan, Kaltman, Rebecca, Puhalla, Shannon, Gudena, Vinay, Carey, Lisa A., Dees, Elizabeth Claire, Muss, Hyman B., Reeder‐Hayes, Katherine E., Jolly, Trevor A., Serody, Jonathan S., Anders, Carey K.

Year: 2017

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2017.35.15_suppl.tps1125

Paper Association of thyroid transcription factor-1 (TTF-1) expression with efficacy of PD-1/PD-L1 inhibitors plus pemetrexed and platinum chemotherapy in advanced non-squamous non-small cell lung cancer.

Ibusuki, Ritsu, Yoneshima, Yasuto, Hashisako, Mikiko, Matsuo, Norikazu, Harada, Taishi, Tsuchiya-Kawano, Yuko, Kishimoto, Junji, Ota, Keiichi, Shiraishi, Yoshimasa, Iwama, Eiji, Tanaka, Kentaro, Oda, Yoshinao, Okamoto, Isamu · 2022 · Translational lung cancer research · DOI

Full title: Association of thyroid transcription factor-1 (TTF-1) expression with efficacy of PD-1/PD-L1 inhibitors plus pemetrexed and platinum chemotherapy in advanced non-squamous non-small cell lung cancer.

Authors: Ibusuki, Ritsu, Yoneshima, Yasuto, Hashisako, Mikiko, Matsuo, Norikazu, Harada, Taishi, Tsuchiya-Kawano, Yuko, Kishimoto, Junji, Ota, Keiichi, Shiraishi, Yoshimasa, Iwama, Eiji, Tanaka, Kentaro, Oda, Yoshinao, Okamoto, Isamu

Year: 2022

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-22-393

Paper Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma.

Moya-Plana, Antoine, Herrera Gómez, Ruth Gabriela, Rossoni, Caroline, Dercle, Laurent, Ammari, Samy, Girault, Isabelle, Roy, Séverine, Scoazec, Jean-Yves, Vagner, Stephan, Janot, François, Eggermont, Alexander M M, Robert, Caroline · 2019 · Cancer immunology, immunotherapy : CII · DOI

Full title: Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma.

Authors: Moya-Plana, Antoine, Herrera Gómez, Ruth Gabriela, Rossoni, Caroline, Dercle, Laurent, Ammari, Samy, Girault, Isabelle, Roy, Séverine, Scoazec, Jean-Yves, Vagner, Stephan, Janot, François, Eggermont, Alexander M M, Robert, Caroline

Year: 2019

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-019-02351-7

Paper Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity.

Harui, Airi, McLachlan, Sandra M, Rapoport, Basil, Zarembinski, Thomas I, Roth, Michael D · 2020 · Cancer immunology, immunotherapy : CII · DOI

Full title: Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity.

Authors: Harui, Airi, McLachlan, Sandra M, Rapoport, Basil, Zarembinski, Thomas I, Roth, Michael D

Year: 2020

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02579-8

Paper Shining light on advanced NSCLC in 2017: combining immune checkpoint inhibitors.

Qiao, Meng, Jiang, Tao, Zhou, Caicun · 2018 · Journal of thoracic disease · DOI

Full title: Shining light on advanced NSCLC in 2017: combining immune checkpoint inhibitors.

Authors: Qiao, Meng, Jiang, Tao, Zhou, Caicun

Year: 2018

Venue: Journal of thoracic disease

DOI: https://doi.org/10.21037/jtd.2018.04.99

Paper Use of early circulating tumour DNA dynamics in patients with stage III melanoma receiving neoadjuvant combination immunotherapy.

Chan, Wei Yen, Lee, Jenny, Stewart, Ashleigh, Diefenbach, Russell J., Gonzalez, Maria, Menzies, Alexander M., Blank, Christian U., Scolyer, Richard A., Long, Georgina V., Rizos, Helen · 2024 · Journal of Clinical Oncology · DOI

Full title: Use of early circulating tumour DNA dynamics in patients with stage III melanoma receiving neoadjuvant combination immunotherapy.

Authors: Chan, Wei Yen, Lee, Jenny, Stewart, Ashleigh, Diefenbach, Russell J., Gonzalez, Maria, Menzies, Alexander M., Blank, Christian U., Scolyer, Richard A., Long, Georgina V., Rizos, Helen

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.9577

Paper Efficacy and safety of PD-1/PD-L1 inhibitors plus chemotherapy for triple-negative breast cancer: a systematic review and meta-analysis.

Cui, Wei, Luo, Qing, Sun, Si-Lu, Xu, Jun-Lin, Gu, Hong · 2022 · Recenti progressi in medicina · DOI

Full title: Efficacy and safety of PD-1/PD-L1 inhibitors plus chemotherapy for triple-negative breast cancer: a systematic review and meta-analysis.

Authors: Cui, Wei, Luo, Qing, Sun, Si-Lu, Xu, Jun-Lin, Gu, Hong

Year: 2022

Venue: Recenti progressi in medicina

DOI: https://doi.org/10.1701/3914.38974

Paper Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Full title: Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Year: 2024

DOI: https://doi.org/10.1158/2159-8290.c.7451438

Paper [Efficacy and Management of Adverse Events of Ipilimumab Including Combination Therapy with Nivolumab].

Uhara, Hisashi, Itakura, Eijun · 2019 · Gan to kagaku ryoho. Cancer & chemotherapy

Full title: [Efficacy and Management of Adverse Events of Ipilimumab Including Combination Therapy with Nivolumab].

Authors: Uhara, Hisashi, Itakura, Eijun

Year: 2019

Venue: Gan to kagaku ryoho. Cancer & chemotherapy

Paper HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

Yin, Lei, Li, Wenjia, Chen, Xuxiao, Wang, Ronghao, Zhang, Tao, Meng, Jialin, Zhao, Li, Li, Xu, Yin, Rui, Cheng, Bo, Yang, Huan · 2023 · Advanced Science · DOI

Full title: HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

Authors: Yin, Lei, Li, Wenjia, Chen, Xuxiao, Wang, Ronghao, Zhang, Tao, Meng, Jialin, Zhao, Li, Li, Xu, Yin, Rui, Cheng, Bo, Yang, Huan

Year: 2023

Venue: Advanced Science

DOI: https://doi.org/10.1002/advs.202206955

Paper Breaking the mold: Overcoming resistance to immune checkpoint inhibitors.

Zhao, Menglu, Yan, Chun-Yan, Wei, Ya-Nan, Zhao, Xi-He · 2023 · Antiviral research · DOI

Full title: Breaking the mold: Overcoming resistance to immune checkpoint inhibitors.

Authors: Zhao, Menglu, Yan, Chun-Yan, Wei, Ya-Nan, Zhao, Xi-He

Year: 2023

Venue: Antiviral research

DOI: https://doi.org/10.1016/j.antiviral.2023.105720

Paper Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy.

Kobold, Sebastian, Pantelyushin, Stanislav, Rataj, Felicitas, Vom Berg, Johannes · 2018 · Frontiers in oncology · DOI

Full title: Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy.

Authors: Kobold, Sebastian, Pantelyushin, Stanislav, Rataj, Felicitas, Vom Berg, Johannes

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00285

Paper The efficacy of regorafenib combined with PD-1/PD-L1 inhibitor in advanced or metastatic colorectal cancer: A single arm meta-analysis.

Yang, Fan, Li, Dandan, Li, Baozhong, Yang, Ting, Zhang, Xiaoming, Liu, Zhiqiang, Zong, Liang · 2026 · Medicine · DOI

Full title: The efficacy of regorafenib combined with PD-1/PD-L1 inhibitor in advanced or metastatic colorectal cancer: A single arm meta-analysis.

Authors: Yang, Fan, Li, Dandan, Li, Baozhong, Yang, Ting, Zhang, Xiaoming, Liu, Zhiqiang, Zong, Liang

Year: 2026

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000047284

Paper Effects of Combination of Anti-CTLA-4 and Anti-PD-1 on Gastric Cancer Cells Proliferation, Apoptosis and Metastasis.

Wang, Bin, Qin, Lei, Ren, Mei, Sun, Hao · 2018 · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · DOI

Full title: Effects of Combination of Anti-CTLA-4 and Anti-PD-1 on Gastric Cancer Cells Proliferation, Apoptosis and Metastasis.

Authors: Wang, Bin, Qin, Lei, Ren, Mei, Sun, Hao

Year: 2018

Venue: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

DOI: https://doi.org/10.1159/000492876

Paper Enhancement of antitumor immunity by CTLA-4 antisense oligonucleotides with CpG motif in mice.

Qu, Kuo, Zhu, Mengru, Lu, Feiyu, Zhu, Tong, Wang, Tingli, Wang, Liying, Yu, Yongli · 2025 · International immunopharmacology · DOI

Full title: Enhancement of antitumor immunity by CTLA-4 antisense oligonucleotides with CpG motif in mice.

Authors: Qu, Kuo, Zhu, Mengru, Lu, Feiyu, Zhu, Tong, Wang, Tingli, Wang, Liying, Yu, Yongli

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.115648

Paper The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.

Martins, Filipe, Schiappacasse, Luis, Levivier, Marc, Tuleasca, Constantin, Cuendet, Michel A, Aedo-Lopez, Veronica, Gautron Moura, Bianca, Homicsko, Krisztian, Bettini, Adrienne, Berthod, Gregoire, Gérard, Camille L, Wicky, Alexandre, Bourhis, Jean, Michielin, Olivier · 2020 · Journal of neuro-oncology · DOI

Full title: The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.

Authors: Martins, Filipe, Schiappacasse, Luis, Levivier, Marc, Tuleasca, Constantin, Cuendet, Michel A, Aedo-Lopez, Veronica, Gautron Moura, Bianca, Homicsko, Krisztian, Bettini, Adrienne, Berthod, Gregoire, Gérard, Camille L, Wicky, Alexandre, Bourhis, Jean, Michielin, Olivier

Year: 2020

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-019-03363-0

Paper Dual immune checkpoint blockade in advanced well-differentiated neuroendocrine tumors, a phase II clinical trial.

Scott, Susan C., Jesus‐Acosta, Ana De, Hu, Chen, Levy, Benjamin, Anagnostou, Valsamo, Brahmer, Julie R., Illei, Peter B., Jaffee, Elizabeth M., Marrone, Kristen A., Forde, Patrick M., Hann, Christine L. · 2021 · Journal of Clinical Oncology · DOI

Full title: Dual immune checkpoint blockade in advanced well-differentiated neuroendocrine tumors, a phase II clinical trial.

Authors: Scott, Susan C., Jesus‐Acosta, Ana De, Hu, Chen, Levy, Benjamin, Anagnostou, Valsamo, Brahmer, Julie R., Illei, Peter B., Jaffee, Elizabeth M., Marrone, Kristen A., Forde, Patrick M., Hann, Christine L.

Year: 2021

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2021.39.15_suppl.e16201

Paper A Single-Arm Multi-Center Phase II Clinical Trial of Cadonilimab (anti-PD-1/CTLA-4) in Combination with or without Conventional Second-Line Treatment for Patients with Extensive Stage Small Cell Lung Cancer.

Chen, Can, Chen, Minjun, Bai, Yuju, Li, Yajun, Peng, Jie, Yao, Biao, Feng, Jiangping, Zhou, Jian-Guo, Ma, Hu · 2024 · Technology in cancer research & treatment · DOI

Full title: A Single-Arm Multi-Center Phase II Clinical Trial of Cadonilimab (anti-PD-1/CTLA-4) in Combination with or without Conventional Second-Line Treatment for Patients with Extensive Stage Small Cell Lung Cancer.

Authors: Chen, Can, Chen, Minjun, Bai, Yuju, Li, Yajun, Peng, Jie, Yao, Biao, Feng, Jiangping, Zhou, Jian-Guo, Ma, Hu

Year: 2024

Venue: Technology in cancer research & treatment

DOI: https://doi.org/10.1177/15330338241249690

Paper Phase II study of ipilimumab, nivolumab, and panitumumab in patients with KRAS/NRAS/BRAF wild-type (WT) microsatellite stable (MSS) metastatic colorectal cancer (mCRC).

Lee, Michael Sangmin, Loehrer, Patrick J., Imanirad, Iman, Cohen, Stacey A., Ciombor, Kristen K., Moore, Dominic T., Carlson, Cheryl A., Sanoff, Hanna K., McRee, Autumn J. · 2021 · Journal of Clinical Oncology · DOI

Full title: Phase II study of ipilimumab, nivolumab, and panitumumab in patients with KRAS/NRAS/BRAF wild-type (WT) microsatellite stable (MSS) metastatic colorectal cancer (mCRC).

Authors: Lee, Michael Sangmin, Loehrer, Patrick J., Imanirad, Iman, Cohen, Stacey A., Ciombor, Kristen K., Moore, Dominic T., Carlson, Cheryl A., Sanoff, Hanna K., McRee, Autumn J.

Year: 2021

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2021.39.3_suppl.7

Paper Combining Dual Checkpoint Immunotherapy with Ablative Radiation to All Sites of Oligometastatic Non-Small Cell Lung Cancer: Toxicity and Efficacy Results of a Phase 1b Trial.

Bassetti, Michael F, Morris, Brett A, Sethakorn, Nan, Lang, Joshua M, Schehr, Jennifer L, Zhao, Shuang George, Morris, Zachary S, Buehler, Darya, Eickhoff, Jens C, Harari, Paul M, Traynor, Anne M, Campbell, Toby C, Baschnagel, Andrew M, Leal, Ticiana A · 2024 · International journal of radiation oncology, biology, physics · DOI

Full title: Combining Dual Checkpoint Immunotherapy with Ablative Radiation to All Sites of Oligometastatic Non-Small Cell Lung Cancer: Toxicity and Efficacy Results of a Phase 1b Trial.

Authors: Bassetti, Michael F, Morris, Brett A, Sethakorn, Nan, Lang, Joshua M, Schehr, Jennifer L, Zhao, Shuang George, Morris, Zachary S, Buehler, Darya, Eickhoff, Jens C, Harari, Paul M, Traynor, Anne M, Campbell, Toby C, Baschnagel, Andrew M, Leal, Ticiana A

Year: 2024

Venue: International journal of radiation oncology, biology, physics

DOI: https://doi.org/10.1016/j.ijrobp.2023.11.040

Paper Combining toll-like receptor agonists with immune checkpoint blockade affects antitumor vaccine efficacy.

Jeon, Donghwan, Hill, Ethan, Moseman, Jena E, McNeel, Douglas G · 2024 · Journal for immunotherapy of cancer · DOI

Full title: Combining toll-like receptor agonists with immune checkpoint blockade affects antitumor vaccine efficacy.

Authors: Jeon, Donghwan, Hill, Ethan, Moseman, Jena E, McNeel, Douglas G

Year: 2024

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-008799

Paper The evolving immuno-oncology landscape in advanced lung cancer: first-line treatment of non-small cell lung cancer.

Low, Jia Li, Walsh, Robert J, Ang, Yvonne, Chan, Gloria, Soo, Ross A · 2019 · Therapeutic advances in medical oncology · DOI

Full title: The evolving immuno-oncology landscape in advanced lung cancer: first-line treatment of non-small cell lung cancer.

Authors: Low, Jia Li, Walsh, Robert J, Ang, Yvonne, Chan, Gloria, Soo, Ross A

Year: 2019

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758835919870360

Paper Combination immunotherapy strategies for triple-negative breast cancer: current progress and barriers within the pharmacological landscape

Uliano, Jacopo, Nicolò, Eleonora, Corvaja, Carla, Salimbeni, Beatrice Taurelli, Trapani, Dario, Curigliano, Giuseppe · 2022 · Expert Review of Clinical Pharmacology · DOI

Full title: Combination immunotherapy strategies for triple-negative breast cancer: current progress and barriers within the pharmacological landscape

Authors: Uliano, Jacopo, Nicolò, Eleonora, Corvaja, Carla, Salimbeni, Beatrice Taurelli, Trapani, Dario, Curigliano, Giuseppe

Year: 2022

Venue: Expert Review of Clinical Pharmacology

DOI: https://doi.org/10.1080/17512433.2022.2142559

Paper Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Immune Checkpoint Inhibitors.

Park, Hyo Jung, Qin, Lei, Bakouny, Ziad, Krajewski, Katherine M, Van Allen, Eliezer M, Choueiri, Toni K, Shinagare, Atul B · 2022 · The oncologist · DOI

Full title: Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Immune Checkpoint Inhibitors.

Authors: Park, Hyo Jung, Qin, Lei, Bakouny, Ziad, Krajewski, Katherine M, Van Allen, Eliezer M, Choueiri, Toni K, Shinagare, Atul B

Year: 2022

Venue: The oncologist

DOI: https://doi.org/10.1093/oncolo/oyac034

Paper Novel Immunotherapy Combinations.

Bashir, Babar, Wilson, Melissa A · 2019 · Current oncology reports · DOI

Full title: Novel Immunotherapy Combinations.

Authors: Bashir, Babar, Wilson, Melissa A

Year: 2019

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-019-0851-x

Paper Firing up the cold tumors by targeting Vps34.

Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, Berchem, Guy, Noman, Muhammad Zaeem · 2020 · Oncoimmunology · DOI

Full title: Firing up the cold tumors by targeting Vps34.

Authors: Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, Berchem, Guy, Noman, Muhammad Zaeem

Year: 2020

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2020.1809936

Paper Cancer immunotherapy-associated hypophysitis.

Solinas, Cinzia, Porcu, Michele, De Silva, Pushpamali, Musi, Marco, Aspeslagh, Sandrine, Scartozzi, Mario, Willard-Gallo, Karen, Mariotti, Stefano, Saba, Luca · 2018 · Seminars in oncology · DOI

Full title: Cancer immunotherapy-associated hypophysitis.

Authors: Solinas, Cinzia, Porcu, Michele, De Silva, Pushpamali, Musi, Marco, Aspeslagh, Sandrine, Scartozzi, Mario, Willard-Gallo, Karen, Mariotti, Stefano, Saba, Luca

Year: 2018

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2018.09.002

Paper Post-immunotherapy CTLA-4 Ig treatment improves antitumor efficacy.

Mok, Stephen, Ağaç Çobanoğlu, Didem, Liu, Huey, Mancuso, James J, Allison, James P · 2024 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Post-immunotherapy CTLA-4 Ig treatment improves antitumor efficacy.

Authors: Mok, Stephen, Ağaç Çobanoğlu, Didem, Liu, Huey, Mancuso, James J, Allison, James P

Year: 2024

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2404661121

Paper [Autoimmune hypophysitis associated with new anti-cancer immunotherapies].

Jannin, Arnaud, Merlen, Emilie, Do Cao, Christine, Penel, Nicolas · 2018 · Bulletin du cancer · DOI

Full title: [Autoimmune hypophysitis associated with new anti-cancer immunotherapies].

Authors: Jannin, Arnaud, Merlen, Emilie, Do Cao, Christine, Penel, Nicolas

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2017.10.033

Paper Developing combination immunotherapies against cancer that make sense

Veillette, André, Davidson, Dominique · 2018 · Science Immunology · DOI

Full title: Developing combination immunotherapies against cancer that make sense

Authors: Veillette, André, Davidson, Dominique

Year: 2018

Venue: Science Immunology

DOI: https://doi.org/10.1126/sciimmunol.aav1872

Paper The impact of PD-L1 as a biomarker of cancer responses to combo anti-PD-1/CTLA-4.

Parvini, Sasan, Majidpoor, Jamal, Mortezaee, Keywan · 2023 · Pathology, research and practice · DOI

Full title: The impact of PD-L1 as a biomarker of cancer responses to combo anti-PD-1/CTLA-4.

Authors: Parvini, Sasan, Majidpoor, Jamal, Mortezaee, Keywan

Year: 2023

Venue: Pathology, research and practice

DOI: https://doi.org/10.1016/j.prp.2023.154583

Paper Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.

Levine, Lauren S, Mahuron, Kelly M, Tsai, Katy K, Wu, Clinton, Mattis, Daiva M, Pauli, Mariela L, Oglesby, Arielle, Lee, James C, Spitzer, Matthew H, Krummel, Matthew F, Algazi, Alain P, Rosenblum, Michael D, Alvarado, Michael, Daud, Adil I · 2020 · Annals of surgical oncology · DOI

Full title: Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.

Authors: Levine, Lauren S, Mahuron, Kelly M, Tsai, Katy K, Wu, Clinton, Mattis, Daiva M, Pauli, Mariela L, Oglesby, Arielle, Lee, James C, Spitzer, Matthew H, Krummel, Matthew F, Algazi, Alain P, Rosenblum, Michael D, Alvarado, Michael, Daud, Adil I

Year: 2020

Venue: Annals of surgical oncology

DOI: https://doi.org/10.1245/s10434-020-08648-7

Paper Data from CD4+ T Cells Mediate MHC-Deficient Tumor Rejection and Endothelial Cell Reprogramming

Kim, Samuel I., Haerr, Margaret, Al-Ghezi, Maryam, Chen, Canping, Zhang, Yi, Phipps, Jackie L., Arora, Charu, Gribbin, Kyle P., Kim, G.T., Markosyan, Nune, Xia, Zheng, Vonderheide, Robert H., Byrne, Katelyn T. · 2026 · DOI

Full title: Data from CD4+ T Cells Mediate MHC-Deficient Tumor Rejection and Endothelial Cell Reprogramming

Authors: Kim, Samuel I., Haerr, Margaret, Al-Ghezi, Maryam, Chen, Canping, Zhang, Yi, Phipps, Jackie L., Arora, Charu, Gribbin, Kyle P., Kim, G.T., Markosyan, Nune, Xia, Zheng, Vonderheide, Robert H., Byrne, Katelyn T.

Year: 2026

DOI: https://doi.org/10.1158/2326-6066.c.8235390

Paper Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1.

Chen, Weimin, Pandey, Madhu, Sun, Hong, Rolong, Andrea, Cao, Mingyan, Liu, Dengfeng, Wang, Jihong, Zeng, Lingmin, Hunter, Alan, Lin, Shihua · 2021 · mAbs · DOI

Full title: Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1.

Authors: Chen, Weimin, Pandey, Madhu, Sun, Hong, Rolong, Andrea, Cao, Mingyan, Liu, Dengfeng, Wang, Jihong, Zeng, Lingmin, Hunter, Alan, Lin, Shihua

Year: 2021

Venue: mAbs

DOI: https://doi.org/10.1080/19420862.2021.1914359

Paper PD-L1 expression by immunohistochemistry in salivary duct carcinoma.

A. Hamza, Dianna Roberts, S. Su, R. Weber, D. Bell, R. Ferrarotto · 2019 · Annals of Diagnostic Pathology · DOI

Full title: PD-L1 expression by immunohistochemistry in salivary duct carcinoma.

Authors: A. Hamza, Dianna Roberts, S. Su, R. Weber, D. Bell, R. Ferrarotto

Year: 2019

Venue: Annals of Diagnostic Pathology

DOI: https://doi.org/10.1016/j.anndiagpath.2019.04.001

Paper Development of a kidney cancer ex vivo tumor model and image-based artificial intelligence tool for precision immunotherapy and combination therapy testing.

Eleonora Peerani, Jay Kearney, D. Wiskerke, T. Richardson, G. A. Primo, Keqian Nan, Francesco Iori, Elli Tham, George R. de Fraine, A. Crawley, Chandan Seth Nanda, Matthew H. Williams, M. Tran, D. Ranatunga · 2023 · Journal of Clinical Oncology · DOI

Full title: Development of a kidney cancer ex vivo tumor model and image-based artificial intelligence tool for precision immunotherapy and combination therapy testing.

Authors: Eleonora Peerani, Jay Kearney, D. Wiskerke, T. Richardson, G. A. Primo, Keqian Nan, Francesco Iori, Elli Tham, George R. de Fraine, A. Crawley, Chandan Seth Nanda, Matthew H. Williams, M. Tran, D. Ranatunga

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.16_suppl.e16525

Paper [The role of immunooncology in the treatment of urothelial cancer].

Retz, Margitta, Tauber, Robert, Horn, Thomas · 2017 · Aktuelle Urologie · DOI

Full title: [The role of immunooncology in the treatment of urothelial cancer].

Authors: Retz, Margitta, Tauber, Robert, Horn, Thomas

Year: 2017

Venue: Aktuelle Urologie

DOI: https://doi.org/10.1055/s-0043-107041

Paper The combination therapy with the cytotoxic T lymphocyte-associated antigen-4 and programmed death 1 antibody-induced asthma in a patient with advanced melanoma.

Xu, Weiran, Lian, Bin, Cui, Chuanliang, Guo, Jun · 2021 · Journal of cancer research and therapeutics · DOI

Full title: The combination therapy with the cytotoxic T lymphocyte-associated antigen-4 and programmed death 1 antibody-induced asthma in a patient with advanced melanoma.

Authors: Xu, Weiran, Lian, Bin, Cui, Chuanliang, Guo, Jun

Year: 2021

Venue: Journal of cancer research and therapeutics

DOI: https://doi.org/10.4103/jcrt.jcrt_419_21

Paper Novel Immune Modulatory Agents in the Treatment of Non-small Cell Lung Cancer.

Reyes, Amanda, Lee, Matthew · 2025 · Cancer treatment and research · DOI

Full title: Novel Immune Modulatory Agents in the Treatment of Non-small Cell Lung Cancer.

Authors: Reyes, Amanda, Lee, Matthew

Year: 2025

Venue: Cancer treatment and research

DOI: https://doi.org/10.1007/978-3-031-97242-3_8

Paper Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review.

Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu · 2020 · Frontiers in oncology · DOI

Full title: Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review.

Authors: Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.602705

Paper Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies.

Tselikas, Lambros, de Baere, Thierry, Isoardo, Thomas, Susini, Sandrine, Ser-Le Roux, Karine, Polrot, Mélanie, Adam, Julien, Rouanne, Mathieu, Zitvogel, Laurence, Moine, Laurence, Deschamps, Fréderic, Marabelle, Aurélien · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies.

Authors: Tselikas, Lambros, de Baere, Thierry, Isoardo, Thomas, Susini, Sandrine, Ser-Le Roux, Karine, Polrot, Mélanie, Adam, Julien, Rouanne, Mathieu, Zitvogel, Laurence, Moine, Laurence, Deschamps, Fréderic, Marabelle, Aurélien

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-000579

Paper Time to abandon single-site irradiation for inducing abscopal effects.

Brooks, Eric D, Chang, Joe Y · 2019 · Nature reviews. Clinical oncology · DOI

Full title: Time to abandon single-site irradiation for inducing abscopal effects.

Authors: Brooks, Eric D, Chang, Joe Y

Year: 2019

Venue: Nature reviews. Clinical oncology

DOI: https://doi.org/10.1038/s41571-018-0119-7

Paper Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade.

Blanchard, Lucas, Vina, Estefania, Ljubetic, Jerko, Meneur, Cécile, Tarroux, Dorian, Baez, Maria, Marino, Alessandra, Ortega, Nathalie, Knorr, David A, Ravetch, Jeffrey V, Girard, Jean-Philippe · 2025 · Cell reports. Medicine · DOI

Full title: Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade.

Authors: Blanchard, Lucas, Vina, Estefania, Ljubetic, Jerko, Meneur, Cécile, Tarroux, Dorian, Baez, Maria, Marino, Alessandra, Ortega, Nathalie, Knorr, David A, Ravetch, Jeffrey V, Girard, Jean-Philippe

Year: 2025

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2025.102141

Paper Immunotherapy for Prostate Cancer-Why Now?

Kates, Max, Drake, Charles G · 2017 · Urology practice · DOI

Full title: Immunotherapy for Prostate Cancer-Why Now?

Authors: Kates, Max, Drake, Charles G

Year: 2017

Venue: Urology practice

DOI: https://doi.org/10.1016/j.urpr.2016.07.010

Paper Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial.

A. Stein, L. Paschold, J. Tintelnot, E. Goekkurt, S. Henkes, D. Simnica, C. Schultheiss, E. Willscher, M. Bauer, C. Wickenhauser, P. Thuss-Patience, S. Lorenzen, T. Ettrich, J. Riera-Knorrenschild, L. Jacobasch, A. Kretzschmar, S. Kubicka, S. Al-Batran, A. Reinacher-Schick, D. Pink, M. Sinn, U. Lindig, W. Hiegl, A. Hinke, S. Hegewisch‐Becker, M. Binder · 2022 · JAMA Oncology · DOI

Full title: Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial.

Authors: A. Stein, L. Paschold, J. Tintelnot, E. Goekkurt, S. Henkes, D. Simnica, C. Schultheiss, E. Willscher, M. Bauer, C. Wickenhauser, P. Thuss-Patience, S. Lorenzen, T. Ettrich, J. Riera-Knorrenschild, L. Jacobasch, A. Kretzschmar, S. Kubicka, S. Al-Batran, A. Reinacher-Schick, D. Pink, M. Sinn, U. Lindig, W. Hiegl, A. Hinke, S. Hegewisch‐Becker, M. Binder

Year: 2022

Venue: JAMA Oncology

DOI: https://doi.org/10.1001/jamaoncol.2022.2228

Paper Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone microenvironment.

Subudhi, Sumit K, Siddiqui, Bilal A, Aparicio, Ana M, Yadav, Shalini S, Basu, Sreyashi, Chen, Hong, Jindal, Sonali, Tidwell, Rebecca S S, Varma, Ashwin, Logothetis, Christopher J, Allison, James P, Corn, Paul G, Sharma, Padmanee · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone microenvironment.

Authors: Subudhi, Sumit K, Siddiqui, Bilal A, Aparicio, Ana M, Yadav, Shalini S, Basu, Sreyashi, Chen, Hong, Jindal, Sonali, Tidwell, Rebecca S S, Varma, Ashwin, Logothetis, Christopher J, Allison, James P, Corn, Paul G, Sharma, Padmanee

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2021-002919

Paper Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy.

Shiuan, Eileen, Beckermann, Kathryn E, Ozgun, Alpaslan, Kelly, Ciara, McKean, Meredith, McQuade, Jennifer, Thompson, Mary Ann, Puzanov, Igor, Greer, John P, Rapisuwon, Suthee, Postow, Michael, Davies, Michael A, Eroglu, Zeynep, Johnson, Douglas · 2017 · Journal for immunotherapy of cancer · DOI

Full title: Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy.

Authors: Shiuan, Eileen, Beckermann, Kathryn E, Ozgun, Alpaslan, Kelly, Ciara, McKean, Meredith, McQuade, Jennifer, Thompson, Mary Ann, Puzanov, Igor, Greer, John P, Rapisuwon, Suthee, Postow, Michael, Davies, Michael A, Eroglu, Zeynep, Johnson, Douglas

Year: 2017

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-017-0210-0

Paper The safety of talimogene laherparepvec for the treatment of advanced melanoma.

Gangi, Alexandra, Zager, Jonathan S · 2017 · Expert opinion on drug safety · DOI

Full title: The safety of talimogene laherparepvec for the treatment of advanced melanoma.

Authors: Gangi, Alexandra, Zager, Jonathan S

Year: 2017

Venue: Expert opinion on drug safety

DOI: https://doi.org/10.1080/14740338.2017.1274729

Paper PolyI:C and CpG Synergize with Anti-ErbB2 mAb for Treatment of Breast Tumors Resistant to Immune Checkpoint Inhibitors.

Charlebois, Roxanne, Allard, Bertrand, Allard, David, Buisseret, Laurence, Turcotte, Martin, Pommey, Sandra, Chrobak, Pavel, Stagg, John · 2017 · Cancer research · DOI

Full title: PolyI:C and CpG Synergize with Anti-ErbB2 mAb for Treatment of Breast Tumors Resistant to Immune Checkpoint Inhibitors.

Authors: Charlebois, Roxanne, Allard, Bertrand, Allard, David, Buisseret, Laurence, Turcotte, Martin, Pommey, Sandra, Chrobak, Pavel, Stagg, John

Year: 2017

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-16-1873

Paper Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer.

Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer.

Authors: Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-001607

Paper Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next-Generation Approaches.

Pandey, Asmita, Rai, Sudhir Kumar, Ma, Li, Higa, Lauren, Khadka, Vedbar, Yang, Hua, Deng, Youping · 2026 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next-Generation Approaches.

Authors: Pandey, Asmita, Rai, Sudhir Kumar, Ma, Li, Higa, Lauren, Khadka, Vedbar, Yang, Hua, Deng, Youping

Year: 2026

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202518960

Paper Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy.

Troncoso, Joel Rodriguez, Diaz, Paola Monterroso, Lee, David E, Quick, Charles M, Rajaram, Narasimhan · 2021 · Biomedical optics express · DOI

Full title: Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy.

Authors: Troncoso, Joel Rodriguez, Diaz, Paola Monterroso, Lee, David E, Quick, Charles M, Rajaram, Narasimhan

Year: 2021

Venue: Biomedical optics express

DOI: https://doi.org/10.1364/BOE.426879

Paper Can Immune-related adverse events serve as clinical biomarkers of PD-1/PD-L1 inhibitor efficacy in Pan-Cancer Patients?

Ye, Ziqi, Zheng, Shiyu, Chen, Jie, Zhang, Yanfang, Yang, Si, Hong, Yun, Yang, Hongyu, Xuan, Zixue, Zhao, Qingwei · 2022 · International immunopharmacology · DOI

Full title: Can Immune-related adverse events serve as clinical biomarkers of PD-1/PD-L1 inhibitor efficacy in Pan-Cancer Patients?

Authors: Ye, Ziqi, Zheng, Shiyu, Chen, Jie, Zhang, Yanfang, Yang, Si, Hong, Yun, Yang, Hongyu, Xuan, Zixue, Zhao, Qingwei

Year: 2022

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2022.108738

Paper Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Ajani, Jaffer A., D’Amico, Thomas A., Bentrem, David J., Chao, Joseph, Cooke, David T., Corvera, Carlos U., Das, Prajnan, Enzinger, Peter C., Enzler, Thomas, Fanta, Paul T., Farjah, Farhood, Gerdes, Hans, Gibson, Michael K., Hochwald, Steven N., Hofstetter, Wayne L., Ilson, David H., Keswani, Rajesh N., Kim, Sunnie S. Y., Kleinberg, Lawrence, Klempner, Samuel J., Lacy, Jill, Ly, Quan P., Matkowskyj, Kristina A., McNamara, Michael J., Mulcahy, Mary F., Outlaw, Darryl, Park, Haeseong, Perry, Kyle A., Pimiento, José M., Poultsides, George A., Reznik, Scott I., Roses, Robert E., Strong, Vivian E., Su, Stacey, Wang, Hanlin L., Wiesner, Georgia L., Willett, Christopher G., Yakoub, Danny, Yoon, Harry H., McMillian, Nicole R., Pluchino, Lenora A. · 2022 · Journal of the National Comprehensive Cancer Network · DOI

Full title: Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Authors: Ajani, Jaffer A., D’Amico, Thomas A., Bentrem, David J., Chao, Joseph, Cooke, David T., Corvera, Carlos U., Das, Prajnan, Enzinger, Peter C., Enzler, Thomas, Fanta, Paul T., Farjah, Farhood, Gerdes, Hans, Gibson, Michael K., Hochwald, Steven N., Hofstetter, Wayne L., Ilson, David H., Keswani, Rajesh N., Kim, Sunnie S. Y., Kleinberg, Lawrence, Klempner, Samuel J., Lacy, Jill, Ly, Quan P., Matkowskyj, Kristina A., McNamara, Michael J., Mulcahy, Mary F., Outlaw, Darryl, Park, Haeseong, Perry, Kyle A., Pimiento, José M., Poultsides, George A., Reznik, Scott I., Roses, Robert E., Strong, Vivian E., Su, Stacey, Wang, Hanlin L., Wiesner, Georgia L., Willett, Christopher G., Yakoub, Danny, Yoon, Harry H., McMillian, Nicole R., Pluchino, Lenora A.

Year: 2022

Venue: Journal of the National Comprehensive Cancer Network

DOI: https://doi.org/10.6004/jnccn.2022.0008

Paper The CD155/TIGIT Axis Promotes and Maintains Immune Evasion in Neoantigen-Expressing Pancreatic Cancer

Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Patiño‐García, Ana, Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Bronson, Roderick T., Westcott, Peter M.K., Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yılmaz, Ömer, Regev, Aviv, Jacks, Tyler · 2020 · SSRN Electronic Journal · DOI

Full title: The CD155/TIGIT Axis Promotes and Maintains Immune Evasion in Neoantigen-Expressing Pancreatic Cancer

Authors: Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Patiño‐García, Ana, Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Bronson, Roderick T., Westcott, Peter M.K., Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yılmaz, Ömer, Regev, Aviv, Jacks, Tyler

Year: 2020

Venue: SSRN Electronic Journal

DOI: https://doi.org/10.2139/ssrn.3753805

Paper CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES

Sun, Lu, Lee, Eudocia Q., Li, Gang, Reardon, David A., Acevedo, Brenda, Westergaard, Catharina, Russ, Alyssa, Everson, Richard G., Ellingson, Benjamin M., Mellinghoff, Ingo K., Aquilanti, Elisa, Castro, L. Nicolas Gonzalez, McFaline-Figueroa, J Ricardo, Nayak, Lakshmi, Beroukhim, Rameen, Chong, Robert, Stone, Jacqueline, Kaley, Thomas, Schaff, Lauren, Wilcox, James A., Lavallee, Maria, Chukwueke, Ugonma, Abbeele, Annick D. Van den, Lim, Michael, Cloughesy, Timothy F., Prins, Robert M., Wen, Patrick Y. · 2025 · Neuro-Oncology · DOI

Full title: CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES

Authors: Sun, Lu, Lee, Eudocia Q., Li, Gang, Reardon, David A., Acevedo, Brenda, Westergaard, Catharina, Russ, Alyssa, Everson, Richard G., Ellingson, Benjamin M., Mellinghoff, Ingo K., Aquilanti, Elisa, Castro, L. Nicolas Gonzalez, McFaline-Figueroa, J Ricardo, Nayak, Lakshmi, Beroukhim, Rameen, Chong, Robert, Stone, Jacqueline, Kaley, Thomas, Schaff, Lauren, Wilcox, James A., Lavallee, Maria, Chukwueke, Ugonma, Abbeele, Annick D. Van den, Lim, Michael, Cloughesy, Timothy F., Prins, Robert M., Wen, Patrick Y.

Year: 2025

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noaf201.0469

Paper Orchestrating immune check-point blockade for cancer immunotherapy in combinations.

Perez-Gracia, Jose Luis, Labiano, Sara, Rodriguez-Ruiz, Maria E, Sanmamed, Miguel F, Melero, Ignacio · 2014 · Current opinion in immunology · DOI

Full title: Orchestrating immune check-point blockade for cancer immunotherapy in combinations.

Authors: Perez-Gracia, Jose Luis, Labiano, Sara, Rodriguez-Ruiz, Maria E, Sanmamed, Miguel F, Melero, Ignacio

Year: 2014

Venue: Current opinion in immunology

DOI: https://doi.org/10.1016/j.coi.2014.01.002

Paper Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Hellmann, Matthew D, Nathanson, Tavi, Rizvi, Hira, Creelan, Benjamin C, Sanchez-Vega, Francisco, Ahuja, Arun, Ni, Ai, Novik, Jacki B, Mangarin, Levi M B, Abu-Akeel, Mohsen, Liu, Cailian, Sauter, Jennifer L, Rekhtman, Natasha, Chang, Eliza, Callahan, Margaret K, Chaft, Jamie E, Voss, Martin H, Tenet, Megan, Li, Xue-Mei, Covello, Kelly, Renninger, Andrea, Vitazka, Patrik, Geese, William J, Borghaei, Hossein, Rudin, Charles M, Antonia, Scott J, Swanton, Charles, Hammerbacher, Jeff, Merghoub, Taha, McGranahan, Nicholas, Snyder, Alexandra, Wolchok, Jedd D · 2018 · Cancer cell · DOI

Full title: Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Authors: Hellmann, Matthew D, Nathanson, Tavi, Rizvi, Hira, Creelan, Benjamin C, Sanchez-Vega, Francisco, Ahuja, Arun, Ni, Ai, Novik, Jacki B, Mangarin, Levi M B, Abu-Akeel, Mohsen, Liu, Cailian, Sauter, Jennifer L, Rekhtman, Natasha, Chang, Eliza, Callahan, Margaret K, Chaft, Jamie E, Voss, Martin H, Tenet, Megan, Li, Xue-Mei, Covello, Kelly, Renninger, Andrea, Vitazka, Patrik, Geese, William J, Borghaei, Hossein, Rudin, Charles M, Antonia, Scott J, Swanton, Charles, Hammerbacher, Jeff, Merghoub, Taha, McGranahan, Nicholas, Snyder, Alexandra, Wolchok, Jedd D

Year: 2018

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2018.03.018

Paper Incidence of immune checkpoint inhibitor mediated cardiovascular toxicity: A systematic review and meta-analysis.

Malaty, Michael M, Amarasekera, Anjalee Thanuja, Li, Cindy, Scherrer-Crosbie, Marielle, Tan, Timothy C · 2022 · European journal of clinical investigation · DOI

Full title: Incidence of immune checkpoint inhibitor mediated cardiovascular toxicity: A systematic review and meta-analysis.

Authors: Malaty, Michael M, Amarasekera, Anjalee Thanuja, Li, Cindy, Scherrer-Crosbie, Marielle, Tan, Timothy C

Year: 2022

Venue: European journal of clinical investigation

DOI: https://doi.org/10.1111/eci.13831

Paper Genetic characteristics of platinum-sensitive ovarian clear cell carcinoma

Saito, Ryosuke, Shoburu, Yuichi, Tsuda, Akina, Kuroda, Takafumi, Saito, Motoaki, Tanabe, Hiroshi, Takano, Hirokuni, Yamada, Kyosuke, Kiyokawa, Takako, Kato, Tomoyasu, Kohno, Takashi, Okamoto, Aikou · 2023 · DOI

Full title: Genetic characteristics of platinum-sensitive ovarian clear cell carcinoma

Authors: Saito, Ryosuke, Shoburu, Yuichi, Tsuda, Akina, Kuroda, Takafumi, Saito, Motoaki, Tanabe, Hiroshi, Takano, Hirokuni, Yamada, Kyosuke, Kiyokawa, Takako, Kato, Tomoyasu, Kohno, Takashi, Okamoto, Aikou

Year: 2023

DOI: https://doi.org/10.3802/jgo.2023.34.s1.o41

Paper Comparative safety and survival outcomes of immune checkpoint inhibitors in brain metastases from lung cancer: a propensity-matched cohort study.

Buccilli, Barbara, Yoon, Joseph, Hussein, Amna, Faraji, Amir H · 2025 · Journal of neuro-oncology · DOI

Full title: Comparative safety and survival outcomes of immune checkpoint inhibitors in brain metastases from lung cancer: a propensity-matched cohort study.

Authors: Buccilli, Barbara, Yoon, Joseph, Hussein, Amna, Faraji, Amir H

Year: 2025

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-025-05316-2

Paper Toxicity and efficacy of Gamma Knife radiosurgery for brain metastases in melanoma patients treated with immunotherapy or targeted therapy-A retrospective cohort study.

Gatterbauer, Brigitte, Hirschmann, Dorian, Eberherr, Nadine, Untersteiner, Helena, Cho, Anna, Shaltout, Abdallah, Göbl, Philipp, Fitschek, Fabian, Dorfer, Christian, Wolfsberger, Stefan, Kasprian, Gregor, Höller, Christoph, Frischer, Josa M · 2020 · Cancer medicine · DOI

Full title: Toxicity and efficacy of Gamma Knife radiosurgery for brain metastases in melanoma patients treated with immunotherapy or targeted therapy-A retrospective cohort study.

Authors: Gatterbauer, Brigitte, Hirschmann, Dorian, Eberherr, Nadine, Untersteiner, Helena, Cho, Anna, Shaltout, Abdallah, Göbl, Philipp, Fitschek, Fabian, Dorfer, Christian, Wolfsberger, Stefan, Kasprian, Gregor, Höller, Christoph, Frischer, Josa M

Year: 2020

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.3021

Paper Results of treatment of metastatic melanoma in real clinical practice: optimal choice and sequence of drug administration

E. A. Andreeva, S. V. Cheporov, N. P. Shiryaev · 2026 · Medical alphabet · DOI

Full title: Results of treatment of metastatic melanoma in real clinical practice: optimal choice and sequence of drug administration

Authors: E. A. Andreeva, S. V. Cheporov, N. P. Shiryaev

Year: 2026

Venue: Medical alphabet

DOI: https://doi.org/10.33667/2078-5631-2025-33-53-59

Paper Combination or single-agent ipilimumab as immunotherapy of advanced melanoma: a critical review.

Abdel-Rahman, Omar · 2016 · Melanoma management · DOI

Full title: Combination or single-agent ipilimumab as immunotherapy of advanced melanoma: a critical review.

Authors: Abdel-Rahman, Omar

Year: 2016

Venue: Melanoma management

DOI: https://doi.org/10.2217/mmt-2016-0011

Paper Efficacy and safety of PD-1/PD-L1 immune checkpoint inhibitors in the treatment of recurrent ovarian cancer: A systematic review and meta-analysis.

Chen, Yafang, Liu, Xiaomei, Hu, Ying, Xia, Lingling · 2024 · Medicine · DOI

Full title: Efficacy and safety of PD-1/PD-L1 immune checkpoint inhibitors in the treatment of recurrent ovarian cancer: A systematic review and meta-analysis.

Authors: Chen, Yafang, Liu, Xiaomei, Hu, Ying, Xia, Lingling

Year: 2024

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000038019

Paper Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma - results of a prospective biomarker study.

Forschner, Andrea, Battke, Florian, Hadaschik, Dirk, Schulze, Martin, Weißgraeber, Stephanie, Han, Chung-Ting, Kopp, Maria, Frick, Maximilian, Klumpp, Bernhard, Tietze, Nicola, Amaral, Teresa, Martus, Peter, Sinnberg, Tobias, Eigentler, Thomas, Keim, Ulrike, Garbe, Claus, Döcker, Dennis, Biskup, Saskia · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma - results of a prospective biomarker study.

Authors: Forschner, Andrea, Battke, Florian, Hadaschik, Dirk, Schulze, Martin, Weißgraeber, Stephanie, Han, Chung-Ting, Kopp, Maria, Frick, Maximilian, Klumpp, Bernhard, Tietze, Nicola, Amaral, Teresa, Martus, Peter, Sinnberg, Tobias, Eigentler, Thomas, Keim, Ulrike, Garbe, Claus, Döcker, Dennis, Biskup, Saskia

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0659-0

Paper Advances in clinical trials of targeted therapy and immunotherapy of lung cancer in 2018

Hu, Zhengyang, Li, Ming, Chen, Zhencong, Zhan, Cheng, Lin, Zongwu, Wang, Qun · 2019 · Translational Lung Cancer Research · DOI

Full title: Advances in clinical trials of targeted therapy and immunotherapy of lung cancer in 2018

Authors: Hu, Zhengyang, Li, Ming, Chen, Zhencong, Zhan, Cheng, Lin, Zongwu, Wang, Qun

Year: 2019

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2019.10.17

Paper Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors.

Pietrantonio, Filippo, Lonardi, Sara, Corti, Francesca, Infante, Gabriele, Elez, Maria Elena, Fakih, Marwan, Jayachandran, Priya, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Curigliano, Giuseppe, Cremolini, Chiara, Ambrosini, Margherita, Ros, Javier, Intini, Rossana, Nappo, Floriana, Damian, Silvia, Morano, Federica, Fucà, Giovanni, Overman, Michael, Miceli, Rosalba · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors.

Authors: Pietrantonio, Filippo, Lonardi, Sara, Corti, Francesca, Infante, Gabriele, Elez, Maria Elena, Fakih, Marwan, Jayachandran, Priya, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Curigliano, Giuseppe, Cremolini, Chiara, Ambrosini, Margherita, Ros, Javier, Intini, Rossana, Nappo, Floriana, Damian, Silvia, Morano, Federica, Fucà, Giovanni, Overman, Michael, Miceli, Rosalba

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2021-003370

Paper Autoimmune complications of immunotherapy: pathophysiology and management.

Chan, Karmela K, Bass, Anne R · 2020 · BMJ (Clinical research ed.) · DOI

Full title: Autoimmune complications of immunotherapy: pathophysiology and management.

Authors: Chan, Karmela K, Bass, Anne R

Year: 2020

Venue: BMJ (Clinical research ed.)

DOI: https://doi.org/10.1136/bmj.m736

Paper Endocrine-related adverse events associated with immune-checkpoint inhibitors in patients with melanoma.

Kassi, Eva, Angelousi, Anna, Asonitis, Nikolaos, Diamantopoulos, Panagiotis, Anastasopoulou, Amalia, Papaxoinis, George, Kokkinos, Michalis, Giovanopoulos, Ilias, Kyriakakis, Georgios, Petychaki, Fotini, Savelli, Akrivi, Benopoulou, Olga, Gogas, Helen · 2019 · Cancer medicine · DOI

Full title: Endocrine-related adverse events associated with immune-checkpoint inhibitors in patients with melanoma.

Authors: Kassi, Eva, Angelousi, Anna, Asonitis, Nikolaos, Diamantopoulos, Panagiotis, Anastasopoulou, Amalia, Papaxoinis, George, Kokkinos, Michalis, Giovanopoulos, Ilias, Kyriakakis, Georgios, Petychaki, Fotini, Savelli, Akrivi, Benopoulou, Olga, Gogas, Helen

Year: 2019

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.2533

Paper Prognostic value of neutrophil-lymphocyte ratio and lactate dehydrogenase in melanoma patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis.

Zhang, Yongchao, Liu, Bozhi, Kotenko, Sergei, Li, Wei · 2022 · Medicine · DOI

Full title: Prognostic value of neutrophil-lymphocyte ratio and lactate dehydrogenase in melanoma patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis.

Authors: Zhang, Yongchao, Liu, Bozhi, Kotenko, Sergei, Li, Wei

Year: 2022

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000029536

Paper A Commotion in the Skin: Developing Melanoma Immunotherapies.

Brenner, Ellen, Röcken, Martin · 2022 · The Journal of investigative dermatology · DOI

Full title: A Commotion in the Skin: Developing Melanoma Immunotherapies.

Authors: Brenner, Ellen, Röcken, Martin

Year: 2022

Venue: The Journal of investigative dermatology

DOI: https://doi.org/10.1016/j.jid.2022.01.025

Paper Cryoablation combined with dual immune checkpoint blockade enhances antitumor efficacy in hepatocellular carcinoma model mice.

Gu, Jun, Yu, Zepeng, Tang, Xiangxiang, Chen, Wenying, Deng, Xuedong, Zhu, Xiaoli · 2024 · International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · DOI

Full title: Cryoablation combined with dual immune checkpoint blockade enhances antitumor efficacy in hepatocellular carcinoma model mice.

Authors: Gu, Jun, Yu, Zepeng, Tang, Xiangxiang, Chen, Wenying, Deng, Xuedong, Zhu, Xiaoli

Year: 2024

Venue: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

DOI: https://doi.org/10.1080/02656736.2024.2373319

Paper Cancer immunotherapy: A paradigm shift in the treatment of advanced urologic cancers.

Gill, David M, Agarwal, Neeraj · 2017 · Urologic oncology · DOI

Full title: Cancer immunotherapy: A paradigm shift in the treatment of advanced urologic cancers.

Authors: Gill, David M, Agarwal, Neeraj

Year: 2017

Venue: Urologic oncology

DOI: https://doi.org/10.1016/j.urolonc.2017.09.023

Paper Combination of CTL-associated antigen-4 blockade and depletion of CD25 regulatory T cells enhance tumour immunity of dendritic cell-based vaccine in a mouse model of colon cancer.

Saha, Asim, Chatterjee, S K · 2010 · Scandinavian journal of immunology · DOI

Full title: Combination of CTL-associated antigen-4 blockade and depletion of CD25 regulatory T cells enhance tumour immunity of dendritic cell-based vaccine in a mouse model of colon cancer.

Authors: Saha, Asim, Chatterjee, S K

Year: 2010

Venue: Scandinavian journal of immunology

DOI: https://doi.org/10.1111/j.1365-3083.2009.02355.x

Paper Novel immunotherapeutic approaches in lung cancer: driving beyond programmed death-1/programmed death ligand-1 and cytotoxic T-lymphocyte-associated Protein-4.

Resuli, Blerina, Kauffmann-Guerrero, Diego · 2025 · Current opinion in oncology · DOI

Full title: Novel immunotherapeutic approaches in lung cancer: driving beyond programmed death-1/programmed death ligand-1 and cytotoxic T-lymphocyte-associated Protein-4.

Authors: Resuli, Blerina, Kauffmann-Guerrero, Diego

Year: 2025

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000001106

Paper Exploring novel systemic therapies for pancreatic cancer: a review of emerging anti-PD-1/PD-L1 combination therapy

Zhang, He, Duan, Xiao-Rui, Xing, Lu-Yang, Jia, Yu-Xin, Zhou, Jingyi, Ma, Jianjun · 2022 · Neoplasma · DOI

Full title: Exploring novel systemic therapies for pancreatic cancer: a review of emerging anti-PD-1/PD-L1 combination therapy

Authors: Zhang, He, Duan, Xiao-Rui, Xing, Lu-Yang, Jia, Yu-Xin, Zhou, Jingyi, Ma, Jianjun

Year: 2022

Venue: Neoplasma

DOI: https://doi.org/10.4149/neo_2022_220306n246

Paper Combination approaches in NSCLC involving immune checkpoint inhibitors.

Arulananda, Surein, Rivalland, Gareth, John, Thomas · 2016 · Lung cancer management · DOI

Full title: Combination approaches in NSCLC involving immune checkpoint inhibitors.

Authors: Arulananda, Surein, Rivalland, Gareth, John, Thomas

Year: 2016

Venue: Lung cancer management

DOI: https://doi.org/10.2217/lmt-2016-0013

Paper Optimal timing of steroid initiation in response to CTLA-4 antibody in metastatic cancer: A mathematical model.

Siewe, Nourridine, Friedman, Avner · 2022 · PloS one · DOI

Full title: Optimal timing of steroid initiation in response to CTLA-4 antibody in metastatic cancer: A mathematical model.

Authors: Siewe, Nourridine, Friedman, Avner

Year: 2022

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0277248

Paper Immunotherapy for oncogenic-driven advanced non-small cell lung cancers: Is the time ripe for a change?

Remón, Jordi, Hendriks, Lizza, Cabrera, C., Reguart, Noemı́, Besse, Benjamin · 2018 · Cancer Treatment Reviews · DOI

Full title: Immunotherapy for oncogenic-driven advanced non-small cell lung cancers: Is the time ripe for a change?

Authors: Remón, Jordi, Hendriks, Lizza, Cabrera, C., Reguart, Noemı́, Besse, Benjamin

Year: 2018

Venue: Cancer Treatment Reviews

DOI: https://doi.org/10.1016/j.ctrv.2018.10.006

Paper Durvalumab for the treatment of non-small cell lung cancer

L. Mezquita, D. Planchard · 2018 · Expert Review of Respiratory Medicine · DOI

Full title: Durvalumab for the treatment of non-small cell lung cancer

Authors: L. Mezquita, D. Planchard

Year: 2018

Venue: Expert Review of Respiratory Medicine

DOI: https://doi.org/10.1080/17476348.2018.1494575

Paper P2.11A.13 Cytokine Release Syndrome from Dual Immune Checkpoint Blockade in Non-Small Cell Lung Cancer: FAERS Analysis

Fujiwara, Yukio, Nishimura, Yoshito, Fitzgerald, B.G., George, S., Puzanov, Igor, Dy, Grace K. · 2024 · Journal of Thoracic Oncology · DOI

Full title: P2.11A.13 Cytokine Release Syndrome from Dual Immune Checkpoint Blockade in Non-Small Cell Lung Cancer: FAERS Analysis

Authors: Fujiwara, Yukio, Nishimura, Yoshito, Fitzgerald, B.G., George, S., Puzanov, Igor, Dy, Grace K.

Year: 2024

Venue: Journal of Thoracic Oncology

DOI: https://doi.org/10.1016/j.jtho.2024.09.463

Paper T-cell immunotherapy for melanoma.

Mantilla Rosa, Cristian, Vancheswaran, Aparna, Ariyan, Charlotte E · 2024 · Surgical oncology · DOI

Full title: T-cell immunotherapy for melanoma.

Authors: Mantilla Rosa, Cristian, Vancheswaran, Aparna, Ariyan, Charlotte E

Year: 2024

Venue: Surgical oncology

DOI: https://doi.org/10.1016/j.suronc.2024.102160

Paper Prospective role of PD-1/PD-L1 immune checkpoint inhibitors in GI cancer.

AmeliMojarad, Mandana, AmeliMojarad, Melika, Cui, Xiaonan · 2023 · Pathology, research and practice · DOI

Full title: Prospective role of PD-1/PD-L1 immune checkpoint inhibitors in GI cancer.

Authors: AmeliMojarad, Mandana, AmeliMojarad, Melika, Cui, Xiaonan

Year: 2023

Venue: Pathology, research and practice

DOI: https://doi.org/10.1016/j.prp.2023.154338

Paper Elevated Liver Enzymes in a Patient With Hepatocellular Carcinoma on Immune Checkpoint Inhibitor Therapy: A Diagnostic and Therapeutic Challenge.

Abbas, Daniyal, Zhu, Lee-Ching, Moon, Andrew M · 2022 · ACG case reports journal · DOI

Full title: Elevated Liver Enzymes in a Patient With Hepatocellular Carcinoma on Immune Checkpoint Inhibitor Therapy: A Diagnostic and Therapeutic Challenge.

Authors: Abbas, Daniyal, Zhu, Lee-Ching, Moon, Andrew M

Year: 2022

Venue: ACG case reports journal

DOI: https://doi.org/10.14309/crj.0000000000000834

Paper Toxicities associated with immune checkpoint inhibitors: a systematic study.

Kong, Xiangyi, Chen, Li, Su, Zhaohui, Sullivan, Ryan J, Blum, Steven M, Qi, Zhihong, Liu, Yulu, Huo, Yujia, Fang, Yi, Zhang, Lin, Gao, Jidong, Wang, Jing · 2023 · International journal of surgery (London, England) · DOI

Full title: Toxicities associated with immune checkpoint inhibitors: a systematic study.

Authors: Kong, Xiangyi, Chen, Li, Su, Zhaohui, Sullivan, Ryan J, Blum, Steven M, Qi, Zhihong, Liu, Yulu, Huo, Yujia, Fang, Yi, Zhang, Lin, Gao, Jidong, Wang, Jing

Year: 2023

Venue: International journal of surgery (London, England)

DOI: https://doi.org/10.1097/JS9.0000000000000368

Paper Promising PD-1 antagonists for liver cancer: an evaluation of phase II and III results.

Stella, Leonardo, Hollande, Clemence, Merabet, Yasmina Ben, Fakhouri, Hugo, Leclerc, Vincent, Ponziani, Francesca Romana, Bouattour, Mohamed · 2024 · Expert opinion on emerging drugs · DOI

Full title: Promising PD-1 antagonists for liver cancer: an evaluation of phase II and III results.

Authors: Stella, Leonardo, Hollande, Clemence, Merabet, Yasmina Ben, Fakhouri, Hugo, Leclerc, Vincent, Ponziani, Francesca Romana, Bouattour, Mohamed

Year: 2024

Venue: Expert opinion on emerging drugs

DOI: https://doi.org/10.1080/14728214.2024.2430493

Paper The Treatment Landscape of Advanced Hepatocellular Carcinoma.

Wong, Kit Man, King, Gentry G, Harris, William P · 2022 · Current oncology reports · DOI

Full title: The Treatment Landscape of Advanced Hepatocellular Carcinoma.

Authors: Wong, Kit Man, King, Gentry G, Harris, William P

Year: 2022

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-022-01247-7

Paper Intratumoral delivery of PD-1/PD-L1 and CTLA-4 inhibitors for recurrent/refractory solid tumors: a proof-of-concept treatment strategy.

Tan, Hongye, Shah, Noor Ul Huda, He, Bingjia, Liu, Tianrun, Li, Tianheng, Liu, Manting, Gu, Yingying, Zhi, Cheng, Ou, Yongqiong, Huang, Junhao, Li, Ming, Zuo, Shenghua, Chen, Dongni, Qin, Ruzhai, Yang, Hainan, Li, Xufeng, Lian, Hui, Wu, Qingde, Leidner, Rom, Chen, Rui, Yang, Ankui, Yang, Lili, Zhang, Zhenfeng · 2025 · Frontiers in immunology · DOI

Full title: Intratumoral delivery of PD-1/PD-L1 and CTLA-4 inhibitors for recurrent/refractory solid tumors: a proof-of-concept treatment strategy.

Authors: Tan, Hongye, Shah, Noor Ul Huda, He, Bingjia, Liu, Tianrun, Li, Tianheng, Liu, Manting, Gu, Yingying, Zhi, Cheng, Ou, Yongqiong, Huang, Junhao, Li, Ming, Zuo, Shenghua, Chen, Dongni, Qin, Ruzhai, Yang, Hainan, Li, Xufeng, Lian, Hui, Wu, Qingde, Leidner, Rom, Chen, Rui, Yang, Ankui, Yang, Lili, Zhang, Zhenfeng

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1669924

Paper Neutrophil lymphocyte ratio (NLR) as a predictive biomarker for PD-1/PD-L1 directed therapy in metastatic non-small cell lung cancer (NSCLC).

Naresh Bumma, Ghayathri Jeyakumar, Seongho Kim, C. Galasso, M. Thakur, S. Gadgeel, U. Vaishampayan, A. Wozniak · 2017 · DOI

Full title: Neutrophil lymphocyte ratio (NLR) as a predictive biomarker for PD-1/PD-L1 directed therapy in metastatic non-small cell lung cancer (NSCLC).

Authors: Naresh Bumma, Ghayathri Jeyakumar, Seongho Kim, C. Galasso, M. Thakur, S. Gadgeel, U. Vaishampayan, A. Wozniak

Year: 2017

DOI: https://doi.org/10.1200/jco.2017.35.15_suppl.e20633

Paper Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.

Zhao, Fei, Evans, Kathy, Xiao, Christine, DeVito, Nicholas, Theivanthiran, Balamayooran, Holtzhausen, Alisha, Siska, Peter J, Blobe, Gerard C, Hanks, Brent A · 2018 · Cancer immunology research · DOI

Full title: Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.

Authors: Zhao, Fei, Evans, Kathy, Xiao, Christine, DeVito, Nicholas, Theivanthiran, Balamayooran, Holtzhausen, Alisha, Siska, Peter J, Blobe, Gerard C, Hanks, Brent A

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0086

Paper Immunotherapy for small cell lung cancer: mechanisms of resistance.

Hamilton, Gerhard, Rath, Barbara · 2019 · Expert opinion on biological therapy · DOI

Full title: Immunotherapy for small cell lung cancer: mechanisms of resistance.

Authors: Hamilton, Gerhard, Rath, Barbara

Year: 2019

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2019.1592155

Paper Immune-related adverse events from combination immunotherapy in cancer patients: A comprehensive meta-analysis of randomized controlled trials.

Zhang, Bo, Wu, Qiong, Zhou, You Lang, Guo, Xinyu, Ge, Jun, Fu, Jiaji · 2018 · International immunopharmacology · DOI

Full title: Immune-related adverse events from combination immunotherapy in cancer patients: A comprehensive meta-analysis of randomized controlled trials.

Authors: Zhang, Bo, Wu, Qiong, Zhou, You Lang, Guo, Xinyu, Ge, Jun, Fu, Jiaji

Year: 2018

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2018.08.014

Paper CTLA4 antagonists in phase I and phase II clinical trials, current status and future perspectives for cancer therapy.

Szostak, Bartosz, Machaj, Filip, Rosik, Jakub, Pawlik, Andrzej · 2019 · Expert opinion on investigational drugs · DOI

Full title: CTLA4 antagonists in phase I and phase II clinical trials, current status and future perspectives for cancer therapy.

Authors: Szostak, Bartosz, Machaj, Filip, Rosik, Jakub, Pawlik, Andrzej

Year: 2019

Venue: Expert opinion on investigational drugs

DOI: https://doi.org/10.1080/13543784.2019.1559297

Paper The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy.

Ghidini, Michele, Fusco, Nicola, Salati, Massimiliano, Khakoo, Shelize, Tomasello, Gianluca, Petrelli, Fausto, Trapani, Dario, Petrillo, Angelica · 2021 · Current drug targets · DOI

Full title: The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy.

Authors: Ghidini, Michele, Fusco, Nicola, Salati, Massimiliano, Khakoo, Shelize, Tomasello, Gianluca, Petrelli, Fausto, Trapani, Dario, Petrillo, Angelica

Year: 2021

Venue: Current drug targets

DOI: https://doi.org/10.2174/1389450122666210204204415

Paper Sequential treatment approaches in the management of BRAF wild-type advanced melanoma: a cost-effectiveness analysis.

Tarhini, Ahmad, Benedict, Agnes, McDermott, David, Rao, Sumati, Ambavane, Apoorva, Gupte-Singh, Komal, Sabater, Javier, Ritchings, Corey, Aponte-Ribero, Valerie, Regan, Meredith M, Atkins, Michael · 2018 · Immunotherapy · DOI

Full title: Sequential treatment approaches in the management of BRAF wild-type advanced melanoma: a cost-effectiveness analysis.

Authors: Tarhini, Ahmad, Benedict, Agnes, McDermott, David, Rao, Sumati, Ambavane, Apoorva, Gupte-Singh, Komal, Sabater, Javier, Ritchings, Corey, Aponte-Ribero, Valerie, Regan, Meredith M, Atkins, Michael

Year: 2018

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2018-0085

Paper Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies.

Li, Housaiyin, Zandberg, Dan P, Kulkarni, Aditi, Chiosea, Simion I, Santos, Patricia M, Isett, Brian R, Joy, Marion, Sica, Gabriel L, Contrera, Kevin J, Tatsuoka, Curtis M, Brand, Matthias, Duvvuri, Umamaheswar, Kim, Seungwon, Kubik, Mark, Sridharan, Shaum, Tu, Fei, Chen, Jie, Bruno, Tullia C, Vignali, Dario A A, Cillo, Anthony R, Bao, Riyue, Wang, Jing Hong, Vujanovic, Lazar, Ferris, Robert L · 2025 · Cancer cell · DOI

Full title: Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies.

Authors: Li, Housaiyin, Zandberg, Dan P, Kulkarni, Aditi, Chiosea, Simion I, Santos, Patricia M, Isett, Brian R, Joy, Marion, Sica, Gabriel L, Contrera, Kevin J, Tatsuoka, Curtis M, Brand, Matthias, Duvvuri, Umamaheswar, Kim, Seungwon, Kubik, Mark, Sridharan, Shaum, Tu, Fei, Chen, Jie, Bruno, Tullia C, Vignali, Dario A A, Cillo, Anthony R, Bao, Riyue, Wang, Jing Hong, Vujanovic, Lazar, Ferris, Robert L

Year: 2025

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2025.02.026

Paper Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Wolchok, Jedd D., Chiarion‐Sileni, Vanna, González, René, Rutkowski, Piotr, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Wagstaff, John, Schadendorf, Dirk, Ferrucci, Pier Francesco, Smylie, Michael, Dummer, Reinhard, Hill, Andrew, Hogg, David, Haanen, John B.A.G., Carlino, Matteo S., Bechter, Oliver, Maio, Michele, Márquez‐Rodas, Iván, Guidoboni, Massimo, McArthur, Grant A., Lebbé, Célèste, Ascierto, Paolo A., Long, Georgina V., Cebon, Jonathan, Sosman, Jeffrey A., Postow, Michael A., Callahan, Margaret K., Walker, Damian, Rollin, Linda, Bhore, Rafia, Hodi, F. Stephen, Larkin, James · 2017 · New England Journal of Medicine · DOI

Full title: Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Authors: Wolchok, Jedd D., Chiarion‐Sileni, Vanna, González, René, Rutkowski, Piotr, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Wagstaff, John, Schadendorf, Dirk, Ferrucci, Pier Francesco, Smylie, Michael, Dummer, Reinhard, Hill, Andrew, Hogg, David, Haanen, John B.A.G., Carlino, Matteo S., Bechter, Oliver, Maio, Michele, Márquez‐Rodas, Iván, Guidoboni, Massimo, McArthur, Grant A., Lebbé, Célèste, Ascierto, Paolo A., Long, Georgina V., Cebon, Jonathan, Sosman, Jeffrey A., Postow, Michael A., Callahan, Margaret K., Walker, Damian, Rollin, Linda, Bhore, Rafia, Hodi, F. Stephen, Larkin, James

Year: 2017

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1709684

Paper Prostate cancer immunotherapy.

Mitsogiannis, Iraklis, Tzelves, Lazaros, Dellis, Athanasios, Issa, Hussein, Papatsoris, Athanasios, Moussa, Mohammad · 2022 · Expert opinion on biological therapy · DOI

Full title: Prostate cancer immunotherapy.

Authors: Mitsogiannis, Iraklis, Tzelves, Lazaros, Dellis, Athanasios, Issa, Hussein, Papatsoris, Athanasios, Moussa, Mohammad

Year: 2022

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2022.2027904

Paper A phase II trial of durvalumab (MEDI4736) and tremelimumab with chemotherapy in metastatic EGFR mutant non-squamous non-small cell lung cancer (NSCLC) following progression on EGFR tyrosine kinase inhibitors (TKIs) (ILLUMINATE).

Lee, Chee Khoon, Subramaniam, Shalini, Mersiades, Antony, Mitchell, Jenna, Jurkovic, H., Walker, Mariya, Le, Loc, Brown, Chris, Solomon, Benjamin, John, Thomas, Stockler, Martin R., Liao, Bin-Chi, Yang, James Chih‐Hsin, Chiu, Chao‐Hua · 2020 · Journal of Clinical Oncology · DOI

Full title: A phase II trial of durvalumab (MEDI4736) and tremelimumab with chemotherapy in metastatic EGFR mutant non-squamous non-small cell lung cancer (NSCLC) following progression on EGFR tyrosine kinase inhibitors (TKIs) (ILLUMINATE).

Authors: Lee, Chee Khoon, Subramaniam, Shalini, Mersiades, Antony, Mitchell, Jenna, Jurkovic, H., Walker, Mariya, Le, Loc, Brown, Chris, Solomon, Benjamin, John, Thomas, Stockler, Martin R., Liao, Bin-Chi, Yang, James Chih‐Hsin, Chiu, Chao‐Hua

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.tps9631

Paper Predictive biomarkers of response to immune checkpoint inhibitors in melanoma.

Nebhan, Caroline A, Johnson, Douglas B · 2020 · Expert review of anticancer therapy · DOI

Full title: Predictive biomarkers of response to immune checkpoint inhibitors in melanoma.

Authors: Nebhan, Caroline A, Johnson, Douglas B

Year: 2020

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2020.1724539

Paper Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8+ T cells on clinical outcome of patients with advanced thymic epithelial tumors

J. Duan, Xidong Liu, Hank Chen, Yu Sun, Yi-qiang Liu, H. Bai, Jie Wang · 2018 · Thoracic Cancer · DOI

Full title: Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8+ T cells on clinical outcome of patients with advanced thymic epithelial tumors

Authors: J. Duan, Xidong Liu, Hank Chen, Yu Sun, Yi-qiang Liu, H. Bai, Jie Wang

Year: 2018

Venue: Thoracic Cancer

DOI: https://doi.org/10.1111/1759-7714.12826

Paper Tumor Cell–Intrinsic USP22 Suppresses Antitumor Immunity in Pancreatic Cancer

Li, Jinyang, Yuan, Salina, Norgard, Robert J., Yan, Fangxue, Yamazoe, Taiji, Blanco, Andrés, Stanger, Ben Z. · 2019 · Cancer Immunology Research · DOI

Full title: Tumor Cell–Intrinsic USP22 Suppresses Antitumor Immunity in Pancreatic Cancer

Authors: Li, Jinyang, Yuan, Salina, Norgard, Robert J., Yan, Fangxue, Yamazoe, Taiji, Blanco, Andrés, Stanger, Ben Z.

Year: 2019

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-19-0661

Paper Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.

Greiner, Jochen, Götz, Marlies, Hofmann, Susanne, Schrezenmeier, Hubert, Wiesneth, Markus, Bullinger, Lars, Döhner, Hartmut, Schneider, Vanessa · 2020 · Cancer immunology, immunotherapy : CII · DOI

Full title: Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.

Authors: Greiner, Jochen, Götz, Marlies, Hofmann, Susanne, Schrezenmeier, Hubert, Wiesneth, Markus, Bullinger, Lars, Döhner, Hartmut, Schneider, Vanessa

Year: 2020

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02490-2

Paper Facts and Hopes in Immunotherapy of Soft-Tissue Sarcomas.

Martín-Broto, Javier, Moura, David S, Van Tine, Brian A · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Facts and Hopes in Immunotherapy of Soft-Tissue Sarcomas.

Authors: Martín-Broto, Javier, Moura, David S, Van Tine, Brian A

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-19-3335

Paper CD20+ tumor‐infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma

Sato, Jun, Kitano, Shigehisa, Motoi, Noriko, Ino, Yoshinori, Yamamoto, Noboru, Watanabe, Shun‐ichi, Ohe, Yuichiro, Hiraoka, Nobuyoshi · 2020 · Cancer Science · DOI

Full title: CD20+ tumor‐infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma

Authors: Sato, Jun, Kitano, Shigehisa, Motoi, Noriko, Ino, Yoshinori, Yamamoto, Noboru, Watanabe, Shun‐ichi, Ohe, Yuichiro, Hiraoka, Nobuyoshi

Year: 2020

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.14409

Paper Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice.

Hasegawa, Hisanori, Kawahata, Kimito, Mizoguchi, Fumitaka, Okiyama, Naoko, Miyasaka, Nobuyuki, Kohsaka, Hitoshi · 2017 · Clinical and experimental rheumatology

Full title: Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice.

Authors: Hasegawa, Hisanori, Kawahata, Kimito, Mizoguchi, Fumitaka, Okiyama, Naoko, Miyasaka, Nobuyuki, Kohsaka, Hitoshi

Year: 2017

Venue: Clinical and experimental rheumatology

Paper A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer.

Altorki, Nasser K, Bhinder, Bhavneet, Borczuk, Alain C, Elemento, Olivier, Mittal, Vivek, McGraw, Timothy E · 2024 · Cell reports. Medicine · DOI

Full title: A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer.

Authors: Altorki, Nasser K, Bhinder, Bhavneet, Borczuk, Alain C, Elemento, Olivier, Mittal, Vivek, McGraw, Timothy E

Year: 2024

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2024.101438

Paper Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers.

Ghosh, Soma, O'Hara, Madison P, Sinha, Pragya, Mazumdar, Tuhina, Yapindi, Lacin, Sastry, Jagannadha K, Johnson, Faye M · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers.

Authors: Ghosh, Soma, O'Hara, Madison P, Sinha, Pragya, Mazumdar, Tuhina, Yapindi, Lacin, Sastry, Jagannadha K, Johnson, Faye M

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-009316

Paper Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition.

von Reibnitz, Donata, Chaft, Jamie E, Wu, Abraham J, Samstein, Robert, Hellmann, Matthew D, Plodkowski, Andrew J, Zhang, Zhigang, Shi, Weiji, Dick-Godfrey, Rosalind, Panchoo, Kelly H, Barker, Christopher A, Rimner, Andreas · 2018 · Advances in radiation oncology · DOI

Full title: Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition.

Authors: von Reibnitz, Donata, Chaft, Jamie E, Wu, Abraham J, Samstein, Robert, Hellmann, Matthew D, Plodkowski, Andrew J, Zhang, Zhigang, Shi, Weiji, Dick-Godfrey, Rosalind, Panchoo, Kelly H, Barker, Christopher A, Rimner, Andreas

Year: 2018

Venue: Advances in radiation oncology

DOI: https://doi.org/10.1016/j.adro.2018.05.001

Paper Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas

Judge, Sean J., Darrow, Morgan, Thorpe, Steve W, Gingrich, Alicia A., O’Donnell, Edmond F., Bellini, Alyssa, Sturgill, Ian R., Vick, Logan V., Dunai, Cordelia, Stoffel, Kevin, Lyu, Yue, Chen, Shuai, Cho, May, Rebhun, Robert B., Monjazeb, Arta M., Murphy, William J., Canter, Robert J. · 2020 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas

Authors: Judge, Sean J., Darrow, Morgan, Thorpe, Steve W, Gingrich, Alicia A., O’Donnell, Edmond F., Bellini, Alyssa, Sturgill, Ian R., Vick, Logan V., Dunai, Cordelia, Stoffel, Kevin, Lyu, Yue, Chen, Shuai, Cho, May, Rebhun, Robert B., Monjazeb, Arta M., Murphy, William J., Canter, Robert J.

Year: 2020

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2020-001355

Paper Checkpoint Inhibitors Boost Power of Antibody-Drug Conjugate.

· 2016 · Cancer discovery · DOI

Full title: Checkpoint Inhibitors Boost Power of Antibody-Drug Conjugate.

Year: 2016

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-NB2015-172

Paper Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?

Robert, Lidia, Ribas, Antoni, Hu-Lieskovan, Siwen · 2016 · Seminars in immunology · DOI

Full title: Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?

Authors: Robert, Lidia, Ribas, Antoni, Hu-Lieskovan, Siwen

Year: 2016

Venue: Seminars in immunology

DOI: https://doi.org/10.1016/j.smim.2016.01.001

Paper First-line combination immunotherapy for metastatic non-small cell lung cancer

Chen, Yuh‐Min · 2020 · Journal of the Chinese Medical Association · DOI

Full title: First-line combination immunotherapy for metastatic non-small cell lung cancer

Authors: Chen, Yuh‐Min

Year: 2020

Venue: Journal of the Chinese Medical Association

DOI: https://doi.org/10.1097/jcma.0000000000000287

Paper Combinatorial Cancer Immunotherapies.

Hellmann, Matthew D, Friedman, Claire F, Wolchok, Jedd D · 2016 · Advances in immunology · DOI

Full title: Combinatorial Cancer Immunotherapies.

Authors: Hellmann, Matthew D, Friedman, Claire F, Wolchok, Jedd D

Year: 2016

Venue: Advances in immunology

DOI: https://doi.org/10.1016/bs.ai.2015.12.005

Paper Real-world evidence in metastatic renal cell carcinoma.

Graham, Jeffrey, Heng, Daniel Yc · 2018 · Tumori · DOI

Full title: Real-world evidence in metastatic renal cell carcinoma.

Authors: Graham, Jeffrey, Heng, Daniel Yc

Year: 2018

Venue: Tumori

DOI: https://doi.org/10.1177/0300891618761004

Paper Chemoimmunotherapy versus immune checkpoint inhibitors monotherapy as first‐line treatment for advanced non‐small cell lung cancer

A. Rizzo · 2022 · Thoracic Cancer · DOI

Full title: Chemoimmunotherapy versus immune checkpoint inhibitors monotherapy as first‐line treatment for advanced non‐small cell lung cancer

Authors: A. Rizzo

Year: 2022

Venue: Thoracic Cancer

DOI: https://doi.org/10.1111/1759-7714.14304

Paper Blockade of cytotoxic T-lymphocyte antigen-4 as a new therapeutic approach for advanced melanoma.

Wang, Xiang-Yang, Zuo, Daming, Sarkar, Devanand, Fisher, Paul B · 2011 · Expert opinion on pharmacotherapy · DOI

Full title: Blockade of cytotoxic T-lymphocyte antigen-4 as a new therapeutic approach for advanced melanoma.

Authors: Wang, Xiang-Yang, Zuo, Daming, Sarkar, Devanand, Fisher, Paul B

Year: 2011

Venue: Expert opinion on pharmacotherapy

DOI: https://doi.org/10.1517/14656566.2011.629187

Paper Immune signature-based uncoupling of checkpoint inhibitor efficacy and toxicity.

Lucas, Minke W, Burton, Elizabeth M, Dimitriadis, Petros, Huang, Alexander C, Long, Georgina V, Mitchell, Tara C, Amaria, Rodabe N, Blank, Christian U · 2026 · Immunity · DOI

Full title: Immune signature-based uncoupling of checkpoint inhibitor efficacy and toxicity.

Authors: Lucas, Minke W, Burton, Elizabeth M, Dimitriadis, Petros, Huang, Alexander C, Long, Georgina V, Mitchell, Tara C, Amaria, Rodabe N, Blank, Christian U

Year: 2026

Venue: Immunity

DOI: https://doi.org/10.1016/j.immuni.2025.11.021

Paper Combination of immunotherapy with targeted therapies in advanced non-small cell lung cancer (NSCLC).

Moya-Horno, Irene, Viteri, Santiago, Karachaliou, Niki, Rosell, Rafael · 2018 · Therapeutic advances in medical oncology · DOI

Full title: Combination of immunotherapy with targeted therapies in advanced non-small cell lung cancer (NSCLC).

Authors: Moya-Horno, Irene, Viteri, Santiago, Karachaliou, Niki, Rosell, Rafael

Year: 2018

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758834017745012

Paper CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.

Zappasodi, Roberta, Serganova, Inna, Cohen, Ivan J, Maeda, Masatomo, Shindo, Masahiro, Senbabaoglu, Yasin, Watson, McLane J, Leftin, Avigdor, Maniyar, Rachana, Verma, Svena, Lubin, Matthew, Ko, Myat, Mane, Mayuresh M, Zhong, Hong, Liu, Cailian, Ghosh, Arnab, Abu-Akeel, Mohsen, Ackerstaff, Ellen, Koutcher, Jason A, Ho, Ping-Chih, Delgoffe, Greg M, Blasberg, Ronald, Wolchok, Jedd D, Merghoub, Taha · 2021 · Nature · DOI

Full title: CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.

Authors: Zappasodi, Roberta, Serganova, Inna, Cohen, Ivan J, Maeda, Masatomo, Shindo, Masahiro, Senbabaoglu, Yasin, Watson, McLane J, Leftin, Avigdor, Maniyar, Rachana, Verma, Svena, Lubin, Matthew, Ko, Myat, Mane, Mayuresh M, Zhong, Hong, Liu, Cailian, Ghosh, Arnab, Abu-Akeel, Mohsen, Ackerstaff, Ellen, Koutcher, Jason A, Ho, Ping-Chih, Delgoffe, Greg M, Blasberg, Ronald, Wolchok, Jedd D, Merghoub, Taha

Year: 2021

Venue: Nature

DOI: https://doi.org/10.1038/s41586-021-03326-4

Paper Efficacy and safety of PD-1/PD-L1 and CTLA-4 immune checkpoint inhibitors in colorectal cancer: a meta-analysis.

Jin, Chunhui, Zhu, Xiaodan, Huang, Xiaona, Gong, Tingjie, Wei, Zhipeng, You, Jianliang · 2022 · Journal of comparative effectiveness research · DOI

Full title: Efficacy and safety of PD-1/PD-L1 and CTLA-4 immune checkpoint inhibitors in colorectal cancer: a meta-analysis.

Authors: Jin, Chunhui, Zhu, Xiaodan, Huang, Xiaona, Gong, Tingjie, Wei, Zhipeng, You, Jianliang

Year: 2022

Venue: Journal of comparative effectiveness research

DOI: https://doi.org/10.2217/cer-2021-0134

Paper Successful Pregnancy and Cancer Outcomes With Ipilimumab and Nivolumab for Metastatic Renal Cell Carcinoma: Case Report and Review of the Literature.

Zambrana, Francisco, Barbancho, Carmen, Huelves, Miriam, García de Santiago, Belén, Martín, Yolanda, Muñoz de Lengaria, Marta, de Velasco, Guillermo · 2023 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Successful Pregnancy and Cancer Outcomes With Ipilimumab and Nivolumab for Metastatic Renal Cell Carcinoma: Case Report and Review of the Literature.

Authors: Zambrana, Francisco, Barbancho, Carmen, Huelves, Miriam, García de Santiago, Belén, Martín, Yolanda, Muñoz de Lengaria, Marta, de Velasco, Guillermo

Year: 2023

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000448

Paper New therapeutic targets in melanoma.

Martí, R M, Sorolla, A, Yeramian, A · 2012 · Actas dermo-sifiliograficas · DOI

Full title: New therapeutic targets in melanoma.

Authors: Martí, R M, Sorolla, A, Yeramian, A

Year: 2012

Venue: Actas dermo-sifiliograficas

DOI: https://doi.org/10.1016/j.ad.2011.08.009

Paper Current knowledge of Ipilimumab and its use in treating non-small cell lung cancer.

Pinto, Joseph A, Raez, Luis E, Oliveres, Helena, Rolfo, Christian C · 2019 · Expert opinion on biological therapy · DOI

Full title: Current knowledge of Ipilimumab and its use in treating non-small cell lung cancer.

Authors: Pinto, Joseph A, Raez, Luis E, Oliveres, Helena, Rolfo, Christian C

Year: 2019

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2019.1610380

Paper 213P Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma treated with first-line combination immunotherapies: Results from the International metastatic renal cell carcinoma database consortium (IMDC)

K. Takemura, T. Yuasa, A. Lemelin, E. Ferrier, J.C. Wells, E. Saad, R. Saliby, N.S. Basappa, L. Wood, E. Jude, S. Pål, F. Donskov, B. Beuselinck, B. Szabados, T. Powles, R.R. McKay, G. Gebrael, N. Agarwal, T. Choueiri, D. Heng · 2023 · Annals of Oncology · DOI

Full title: 213P Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma treated with first-line combination immunotherapies: Results from the International metastatic renal cell carcinoma database consortium (IMDC)

Authors: K. Takemura, T. Yuasa, A. Lemelin, E. Ferrier, J.C. Wells, E. Saad, R. Saliby, N.S. Basappa, L. Wood, E. Jude, S. Pål, F. Donskov, B. Beuselinck, B. Szabados, T. Powles, R.R. McKay, G. Gebrael, N. Agarwal, T. Choueiri, D. Heng

Year: 2023

Venue: Annals of Oncology

DOI: https://doi.org/10.1016/j.annonc.2023.10.349

Paper Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversies and future directions.

Soo, Ross A, Lim, Sun Min, Syn, Nicholas L, Teng, Rebecca, Soong, Richie, Mok, Tony S K, Cho, Byoung Chul · 2018 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversies and future directions.

Authors: Soo, Ross A, Lim, Sun Min, Syn, Nicholas L, Teng, Rebecca, Soong, Richie, Mok, Tony S K, Cho, Byoung Chul

Year: 2018

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2017.11.009

Paper TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment.

Azar, Fadi, Deforges, Jules, Demeusoit, Christelle, Kleinpeter, Patricia, Remy, Christelle, Silvestre, Nathalie, Foloppe, Johann, Fend, Laetitia, Spring-Giusti, Clémentine, Quéméneur, Eric, Marchand, Jean-Baptiste · 2024 · Journal for immunotherapy of cancer · DOI

Full title: TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment.

Authors: Azar, Fadi, Deforges, Jules, Demeusoit, Christelle, Kleinpeter, Patricia, Remy, Christelle, Silvestre, Nathalie, Foloppe, Johann, Fend, Laetitia, Spring-Giusti, Clémentine, Quéméneur, Eric, Marchand, Jean-Baptiste

Year: 2024

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-009302

Paper Robotic-assisted cytoreductive partial nephrectomy for metastatic sarcomatoid renal cell carcinoma following dramatic response to combination immunotherapy in a young female.

Bhanji, Yasin, Baraban, Ezra, Antonucci, Brian, Ged, Yasser, Singla, Nirmish · 2023 · Kidney cancer journal : official journal of the Kidney Cancer Association

Full title: Robotic-assisted cytoreductive partial nephrectomy for metastatic sarcomatoid renal cell carcinoma following dramatic response to combination immunotherapy in a young female.

Authors: Bhanji, Yasin, Baraban, Ezra, Antonucci, Brian, Ged, Yasser, Singla, Nirmish

Year: 2023

Venue: Kidney cancer journal : official journal of the Kidney Cancer Association

Paper Stereotactic radiosurgery and anti-PD-1 + CTLA-4 therapy, anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, BRAF inhibitors, or conventional chemotherapy for the management of melanoma brain metastases.

Dohm, Ammoren E, Nakashima, Justyn Y, Kalagotla, Hruday, Jiang, Shirley X, Tang, Joseph D, Bhandari, Menal, Kim, Youngchul, Graham, Jasmine A, Khushalani, Nikhil I, Forsyth, Peter A, Etame, Arnold B, Liu, James K, Tran, Nam D, Vogelbaum, Michael A, Wuthrick, Evan J, Yu, Hsiang-Hsuan Michael, Oliver, Daniel E, Ahmed, Kamran A · 2023 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Stereotactic radiosurgery and anti-PD-1 + CTLA-4 therapy, anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, BRAF inhibitors, or conventional chemotherapy for the management of melanoma brain metastases.

Authors: Dohm, Ammoren E, Nakashima, Justyn Y, Kalagotla, Hruday, Jiang, Shirley X, Tang, Joseph D, Bhandari, Menal, Kim, Youngchul, Graham, Jasmine A, Khushalani, Nikhil I, Forsyth, Peter A, Etame, Arnold B, Liu, James K, Tran, Nam D, Vogelbaum, Michael A, Wuthrick, Evan J, Yu, Hsiang-Hsuan Michael, Oliver, Daniel E, Ahmed, Kamran A

Year: 2023

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2023.113287

Paper Tumor Burden Affects Efficacy of Combination Immunotherapy

· 2019 · Cancer Discovery · DOI

Full title: Tumor Burden Affects Efficacy of Combination Immunotherapy

Year: 2019

Venue: Cancer Discovery

DOI: https://doi.org/10.1158/2159-8290.cd-rw2019-021

Paper Combination immunotherapy with 4-1BBL and CTLA-4 blockade for the treatment of prostate cancer.

Youlin, Kuang, Li, Zhang, Xiaodong, Weng, Xiuheng, Liu, Hengchen, Zhu · 2012 · Clinical & developmental immunology · DOI

Full title: Combination immunotherapy with 4-1BBL and CTLA-4 blockade for the treatment of prostate cancer.

Authors: Youlin, Kuang, Li, Zhang, Xiaodong, Weng, Xiuheng, Liu, Hengchen, Zhu

Year: 2012

Venue: Clinical & developmental immunology

DOI: https://doi.org/10.1155/2012/439235

Paper Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.

Kaptein, Paulien, Jacoberger-Foissac, Celia, Dimitriadis, Petros, Voabil, Paula, de Bruijn, Marjolein, Brokamp, Simone, Reijers, Irene, Versluis, Judith, Nallan, Gahyathiri, Triscott, Hannah, McDonald, Elizabeth, Tay, Joshua, Long, Georgina V, Blank, Christian U, Thommen, Daniela S, Teng, Michele W L · 2022 · Science translational medicine · DOI

Full title: Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.

Authors: Kaptein, Paulien, Jacoberger-Foissac, Celia, Dimitriadis, Petros, Voabil, Paula, de Bruijn, Marjolein, Brokamp, Simone, Reijers, Irene, Versluis, Judith, Nallan, Gahyathiri, Triscott, Hannah, McDonald, Elizabeth, Tay, Joshua, Long, Georgina V, Blank, Christian U, Thommen, Daniela S, Teng, Michele W L

Year: 2022

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.abj9779

Paper Cordycepin synergizes with CTLA-4 blockade to remodel the tumor microenvironment for enhanced cancer immunotherapy.

Chen, Lujun, Zheng, Xiao, Huang, Hao, Feng, Chen, Wu, Shaoxian, Chen, Rongzhang, Jiang, Hongwei, Yuan, Maoling, Fu, Yuanyuan, Ying, Hanjie, Zhou, Jun, Jiang, Jingting · 2023 · International immunopharmacology · DOI

Full title: Cordycepin synergizes with CTLA-4 blockade to remodel the tumor microenvironment for enhanced cancer immunotherapy.

Authors: Chen, Lujun, Zheng, Xiao, Huang, Hao, Feng, Chen, Wu, Shaoxian, Chen, Rongzhang, Jiang, Hongwei, Yuan, Maoling, Fu, Yuanyuan, Ying, Hanjie, Zhou, Jun, Jiang, Jingting

Year: 2023

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.110786

Paper Kidney injuries related to ipilimumab.

Izzedine, Hassane, Gueutin, Victor, Gharbi, Chems, Mateus, Christine, Robert, Caroline, Routier, Emilie, Thomas, Marina, Baumelou, Alain, Rouvier, Philippe · 2014 · Investigational new drugs · DOI

Full title: Kidney injuries related to ipilimumab.

Authors: Izzedine, Hassane, Gueutin, Victor, Gharbi, Chems, Mateus, Christine, Robert, Caroline, Routier, Emilie, Thomas, Marina, Baumelou, Alain, Rouvier, Philippe

Year: 2014

Venue: Investigational new drugs

DOI: https://doi.org/10.1007/s10637-014-0092-7

Paper A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model.

Son, Sumin, Park, Jinho, Seo, Hyodeok, Lee, Hyun Tae, Heo, Yong-Seok, Kim, Hak-Sung · 2020 · Journal of drug targeting · DOI

Full title: A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model.

Authors: Son, Sumin, Park, Jinho, Seo, Hyodeok, Lee, Hyun Tae, Heo, Yong-Seok, Kim, Hak-Sung

Year: 2020

Venue: Journal of drug targeting

DOI: https://doi.org/10.1080/1061186X.2019.1669042

Paper The Safety of Cadonilimab: A Systematic Review and Single-Arm Meta-Analysis.

Zhang, Zhuo, Yu, Jiao, Zhang, Zhiqi, Liu, Qianxin, Pang, Xiaocong, Zhou, Ying · 2025 · Cancer medicine · DOI

Full title: The Safety of Cadonilimab: A Systematic Review and Single-Arm Meta-Analysis.

Authors: Zhang, Zhuo, Yu, Jiao, Zhang, Zhiqi, Liu, Qianxin, Pang, Xiaocong, Zhou, Ying

Year: 2025

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.71210

Paper First‐line PD‐1/PD‐L1 inhibitors plus chemotherapy versus bevacizumab plus chemotherapy for advanced non‐squamous non‐small cell lung cancer: A Bayesian network meta‐analysis of randomized controlled trials

Jin-Hai Zhai, Jian-Xun Lu, Zhibo Zhang, Yuan Wang, Xiao-yan Li, Su-jie Zhang, Shuai Mu, X. Zhi, X. Ge, D. Lu, Yi Hu, Jin-liang Wang · 2022 · Cancer Medicine · DOI

Full title: First‐line PD‐1/PD‐L1 inhibitors plus chemotherapy versus bevacizumab plus chemotherapy for advanced non‐squamous non‐small cell lung cancer: A Bayesian network meta‐analysis of randomized controlled trials

Authors: Jin-Hai Zhai, Jian-Xun Lu, Zhibo Zhang, Yuan Wang, Xiao-yan Li, Su-jie Zhang, Shuai Mu, X. Zhi, X. Ge, D. Lu, Yi Hu, Jin-liang Wang

Year: 2022

Venue: Cancer Medicine

DOI: https://doi.org/10.1002/cam4.4589

Paper Role of radiotherapy in improving activity of immune-modulating drugs in advanced renal cancer: Biological rationale and clinical evidences.

Buttigliero, Consuelo, Allis, Simona, Tucci, Marcello, Zichi, Clizia, Leone, Gianmarco, Di Stefano, Rosario Francesco, Ruo Redda, Maria Grazia, Ricardi, Umberto, Scagliotti, Giorgio Vittorio, Di Maio, Massimo, Filippi, Andrea Riccardo · 2018 · Cancer treatment reviews · DOI

Full title: Role of radiotherapy in improving activity of immune-modulating drugs in advanced renal cancer: Biological rationale and clinical evidences.

Authors: Buttigliero, Consuelo, Allis, Simona, Tucci, Marcello, Zichi, Clizia, Leone, Gianmarco, Di Stefano, Rosario Francesco, Ruo Redda, Maria Grazia, Ricardi, Umberto, Scagliotti, Giorgio Vittorio, Di Maio, Massimo, Filippi, Andrea Riccardo

Year: 2018

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2018.07.010

Paper Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies

Yizhou Zhang, Ruicheng Wei, Ge Song, Xinyi Yang, Meng Zhang, Wei Liu, Aiying Xiong, Xuehan Zhang, Qianhao Li, Wan-Jen Yang, Chencheng Han, Rui Liu, Chen Hu, Qingyu Wang, Jun Zhu, Yongqiang Shan · 2024 · mAbs · DOI

Full title: Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies

Authors: Yizhou Zhang, Ruicheng Wei, Ge Song, Xinyi Yang, Meng Zhang, Wei Liu, Aiying Xiong, Xuehan Zhang, Qianhao Li, Wan-Jen Yang, Chencheng Han, Rui Liu, Chen Hu, Qingyu Wang, Jun Zhu, Yongqiang Shan

Year: 2024

Venue: mAbs

DOI: https://doi.org/10.1080/19420862.2024.2419838

Paper Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models.

Phadke, Manali S, Li, Jiannong, Chen, Zhihua, Rodriguez, Paulo C, Mandula, Jessica K, Karapetyan, Lilit, Forsyth, Peter A, Chen, Y Ann, Smalley, Keiran S M · 2023 · Journal for immunotherapy of cancer · DOI

Full title: Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models.

Authors: Phadke, Manali S, Li, Jiannong, Chen, Zhihua, Rodriguez, Paulo C, Mandula, Jessica K, Karapetyan, Lilit, Forsyth, Peter A, Chen, Y Ann, Smalley, Keiran S M

Year: 2023

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2023-007239

Paper VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors.

Voron, Thibault, Colussi, Orianne, Marcheteau, Elie, Pernot, Simon, Nizard, Mevyn, Pointet, Anne-Laure, Latreche, Sabrina, Bergaya, Sonia, Benhamouda, Nadine, Tanchot, Corinne, Stockmann, Christian, Combe, Pierre, Berger, Anne, Zinzindohoue, Franck, Yagita, Hideo, Tartour, Eric, Taieb, Julien, Terme, Magali · 2015 · The Journal of experimental medicine · DOI

Full title: VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors.

Authors: Voron, Thibault, Colussi, Orianne, Marcheteau, Elie, Pernot, Simon, Nizard, Mevyn, Pointet, Anne-Laure, Latreche, Sabrina, Bergaya, Sonia, Benhamouda, Nadine, Tanchot, Corinne, Stockmann, Christian, Combe, Pierre, Berger, Anne, Zinzindohoue, Franck, Yagita, Hideo, Tartour, Eric, Taieb, Julien, Terme, Magali

Year: 2015

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20140559

Paper Thermosensitive Hydrogel-Mediated Chemo-Photothermal Combined Immunotherapy for Triple-Negative Breast Cancer.

Yi Luo, Zhipeng Liao, Hai-Qin Liao, Yinlin Wu, Wanlin Tan, Mingyu Chen, Yan Xu, Long Wang, Xiangdang Long, Chengcheng Niu · 2025 · ACS Applied Materials and Interfaces · DOI

Full title: Thermosensitive Hydrogel-Mediated Chemo-Photothermal Combined Immunotherapy for Triple-Negative Breast Cancer.

Authors: Yi Luo, Zhipeng Liao, Hai-Qin Liao, Yinlin Wu, Wanlin Tan, Mingyu Chen, Yan Xu, Long Wang, Xiangdang Long, Chengcheng Niu

Year: 2025

Venue: ACS Applied Materials and Interfaces

DOI: https://doi.org/10.1021/acsami.5c17119

Paper Strengthening the Combinational Immunotherapy from Modulating the Tumor Inflammatory Environment via Hypoxia‐Responsive Nanogels

Luo, Wenhe, Zeng, Yanqiao, Song, Qingle, Wang, Yu, Yuan, Feng, Li, Qi, Liu, Yingnan, Li, Su, Jannatun, Nahar, Zhang, Guofang, Li, Yang · 2023 · Advanced Healthcare Materials · DOI

Full title: Strengthening the Combinational Immunotherapy from Modulating the Tumor Inflammatory Environment via Hypoxia‐Responsive Nanogels

Authors: Luo, Wenhe, Zeng, Yanqiao, Song, Qingle, Wang, Yu, Yuan, Feng, Li, Qi, Liu, Yingnan, Li, Su, Jannatun, Nahar, Zhang, Guofang, Li, Yang

Year: 2023

Venue: Advanced Healthcare Materials

DOI: https://doi.org/10.1002/adhm.202302865

Paper Brief Report: Real-World Toxicity and Survival of Combination Immunotherapy in Pleural Mesothelioma-RIOMeso.

McNamee, Nicholas, Harvey, Catriona, Gray, Lauren, Khoo, Trisha, Lingam, Lavanya, Zhang, Betty, Nindra, Udit, Yip, Po Yee, Pal, Abhijit, Clay, Timothy, Arulananda, Surein, Itchins, Malinda, Pavlakis, Nick, Kao, Steven, Bowyer, Samantha, Chin, Venessa, Warburton, Lydia, Pires da Silva, Inês, John, Thomas, Solomon, Benjamin, Alexander, Marliese, Nagrial, Adnan · 2024 · Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · DOI

Full title: Brief Report: Real-World Toxicity and Survival of Combination Immunotherapy in Pleural Mesothelioma-RIOMeso.

Authors: McNamee, Nicholas, Harvey, Catriona, Gray, Lauren, Khoo, Trisha, Lingam, Lavanya, Zhang, Betty, Nindra, Udit, Yip, Po Yee, Pal, Abhijit, Clay, Timothy, Arulananda, Surein, Itchins, Malinda, Pavlakis, Nick, Kao, Steven, Bowyer, Samantha, Chin, Venessa, Warburton, Lydia, Pires da Silva, Inês, John, Thomas, Solomon, Benjamin, Alexander, Marliese, Nagrial, Adnan

Year: 2024

Venue: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

DOI: https://doi.org/10.1016/j.jtho.2023.11.014

Paper Mixing it up: boosting responses with immunotherapy combinations.

Komatsuda, Hiroki, Sim, Edward S, Uppaluri, Ravindra · 2025 · Trends in cancer · DOI

Full title: Mixing it up: boosting responses with immunotherapy combinations.

Authors: Komatsuda, Hiroki, Sim, Edward S, Uppaluri, Ravindra

Year: 2025

Venue: Trends in cancer

DOI: https://doi.org/10.1016/j.trecan.2025.04.013

Paper Immune checkpoint inhibitor-related gastrointestinal adverse events: a disproportionality analysis based on the FAERS database.

Gao, Yuye, Pei, Junpeng, Ji, Dengbo, Chen, Yongjiu, Huang, Yonglin, Wu, Aiwen · 2025 · Expert opinion on drug safety · DOI

Full title: Immune checkpoint inhibitor-related gastrointestinal adverse events: a disproportionality analysis based on the FAERS database.

Authors: Gao, Yuye, Pei, Junpeng, Ji, Dengbo, Chen, Yongjiu, Huang, Yonglin, Wu, Aiwen

Year: 2025

Venue: Expert opinion on drug safety

DOI: https://doi.org/10.1080/14740338.2025.2574669

Paper Immunotherapy for hepatocellular carcinoma.

Zongyi, Yin, Xiaowu, Li · 2020 · Cancer letters · DOI

Full title: Immunotherapy for hepatocellular carcinoma.

Authors: Zongyi, Yin, Xiaowu, Li

Year: 2020

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2019.12.002

Paper Cost-effectiveness of single versus dual immune checkpoint blockade for chemotherapy-refractory esophageal, GE junction, and gastric cancers.

Ostvar, Sassan, Choi, Jin, Chu, Jacqueline N., Nipp, Ryan David, Dougan, Michael, Reynolds, Kerry L., Gainor, Justin F., Kong, Chung Yin, Hur, Chin · 2018 · Journal of Clinical Oncology · DOI

Full title: Cost-effectiveness of single versus dual immune checkpoint blockade for chemotherapy-refractory esophageal, GE junction, and gastric cancers.

Authors: Ostvar, Sassan, Choi, Jin, Chu, Jacqueline N., Nipp, Ryan David, Dougan, Michael, Reynolds, Kerry L., Gainor, Justin F., Kong, Chung Yin, Hur, Chin

Year: 2018

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2018.36.15_suppl.e16089

Paper The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Patiño‐García, Ana, Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Jaeger, Alex M., Bronson, Roderick T., Westcott, Peter M.K., Hether, Tyler, Divakar, Prajan, Reeves, Jason, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yılmaz, Ömer, Regev, Aviv, Jacks, Tyler · 2021 · Cancer Cell · DOI

Full title: The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Authors: Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Patiño‐García, Ana, Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Jaeger, Alex M., Bronson, Roderick T., Westcott, Peter M.K., Hether, Tyler, Divakar, Prajan, Reeves, Jason, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yılmaz, Ömer, Regev, Aviv, Jacks, Tyler

Year: 2021

Venue: Cancer Cell

DOI: https://doi.org/10.1016/j.ccell.2021.07.007

Paper Abstract 6642: Rapid tissue donation identifies LAG3 as a potential therapeutic target for ALK fusion positive lung cancer

Hilal Ozakinci, G. Nazario, K. C. Furlan, Dung-tsa Chen, T. Rose, M. Schabath, E. Haura, B. Pellini, A. Beg, T. Boyle · 2023 · Cancer Research · DOI

Full title: Abstract 6642: Rapid tissue donation identifies LAG3 as a potential therapeutic target for ALK fusion positive lung cancer

Authors: Hilal Ozakinci, G. Nazario, K. C. Furlan, Dung-tsa Chen, T. Rose, M. Schabath, E. Haura, B. Pellini, A. Beg, T. Boyle

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-6642

Paper CTLA-4 blockade enhances antitumor immunity of intratumoral injection of immature dendritic cells into irradiated tumor in a mouse colon cancer model.

Son, Cheol-Hun, Bae, Jae-Ho, Shin, Dong-Yeok, Lee, Hong-Rae, Choi, Yoo-Jin, Jo, Wol-Soon, Ho Jung, Min, Kang, Chi-Dug, Yang, Kwangmo, Park, You-Soo · 2014 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: CTLA-4 blockade enhances antitumor immunity of intratumoral injection of immature dendritic cells into irradiated tumor in a mouse colon cancer model.

Authors: Son, Cheol-Hun, Bae, Jae-Ho, Shin, Dong-Yeok, Lee, Hong-Rae, Choi, Yoo-Jin, Jo, Wol-Soon, Ho Jung, Min, Kang, Chi-Dug, Yang, Kwangmo, Park, You-Soo

Year: 2014

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000007

Paper Recent Progress in Mutation-driven Therapy, Immunotherapy and Combination Therapy for the Treatment of Melanoma.

Assi, Hazem I, Assi, Rita E · 2017 · Current cancer drug targets · DOI

Full title: Recent Progress in Mutation-driven Therapy, Immunotherapy and Combination Therapy for the Treatment of Melanoma.

Authors: Assi, Hazem I, Assi, Rita E

Year: 2017

Venue: Current cancer drug targets

DOI: https://doi.org/10.2174/1568009616666160719120053

Paper Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade.

Saha, Dipongkor, Martuza, Robert L, Rabkin, Samuel D · 2017 · Cancer cell · DOI

Full title: Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade.

Authors: Saha, Dipongkor, Martuza, Robert L, Rabkin, Samuel D

Year: 2017

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2017.07.006

Paper A New VISTA on combination therapy for negative checkpoint regulator blockade.

Deng, Jie, Le Mercier, Isabelle, Kuta, Anna, Noelle, Randolph J · 2016 · Journal for immunotherapy of cancer · DOI

Full title: A New VISTA on combination therapy for negative checkpoint regulator blockade.

Authors: Deng, Jie, Le Mercier, Isabelle, Kuta, Anna, Noelle, Randolph J

Year: 2016

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-016-0190-5

Paper Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells.

Hutmacher, Cornelia, Gonzalo Núñez, Nicolás, Liuzzi, Anna Rita, Becher, Burkhard, Neri, Dario · 2019 · Cancer immunology research · DOI

Full title: Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells.

Authors: Hutmacher, Cornelia, Gonzalo Núñez, Nicolás, Liuzzi, Anna Rita, Becher, Burkhard, Neri, Dario

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0566

Paper Combination immunotherapy: Where do we go from here?

Overacre-Delgoffe, Abigail E., Kurtuluş, Sema, Sznol, Mario, Pardoll, Drew M., Anderson, Ana C., Vignali, Dario A.A. · 2015 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Combination immunotherapy: Where do we go from here?

Authors: Overacre-Delgoffe, Abigail E., Kurtuluş, Sema, Sznol, Mario, Pardoll, Drew M., Anderson, Ana C., Vignali, Dario A.A.

Year: 2015

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-015-0083-z

Paper Efficacy and safety of neoadjuvant combination immunotherapy in surgically resectable malignant solid tumors: a systematic review and meta-analysis.

Feng, Yuqian, Guo, Kaibo, Jin, Huimin, Jiang, Jing, Wang, Menglei, Lin, Shengyou · 2024 · Expert review of anticancer therapy · DOI

Full title: Efficacy and safety of neoadjuvant combination immunotherapy in surgically resectable malignant solid tumors: a systematic review and meta-analysis.

Authors: Feng, Yuqian, Guo, Kaibo, Jin, Huimin, Jiang, Jing, Wang, Menglei, Lin, Shengyou

Year: 2024

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2024.2325404

Paper Phase I trial of KN046, a novel bispecific antibody targeting PD-L1 and CTLA-4 in patients with advanced solid tumors

Ma, Yuxiang, Xue, Jinhui, Zhao, Yuanyuan, Zhang, Yang, Huang, Yan, Yang, Yunpeng, Fang, Wenfeng, Guo, Ye, Li, Qun, Ge, Xiaoxiao, Sun, Jie, Zhang, Bangyong, Zhang, Yuhan, Xiao, Jinyuan, Zhang, Li, Zhao, Hongyun · 2023 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Phase I trial of KN046, a novel bispecific antibody targeting PD-L1 and CTLA-4 in patients with advanced solid tumors

Authors: Ma, Yuxiang, Xue, Jinhui, Zhao, Yuanyuan, Zhang, Yang, Huang, Yan, Yang, Yunpeng, Fang, Wenfeng, Guo, Ye, Li, Qun, Ge, Xiaoxiao, Sun, Jie, Zhang, Bangyong, Zhang, Yuhan, Xiao, Jinyuan, Zhang, Li, Zhao, Hongyun

Year: 2023

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2022-006654

Paper The cyclin-dependent kinase inhibitor AT7519 is a human RORγt agonist.

Karaś, Kaja, Pastwińska, Joanna, Sałkowska, Anna, Karwaciak, Iwona, Bachorz, Rafał A, Ratajewski, Marcin · 2025 · Immunology and cell biology · DOI

Full title: The cyclin-dependent kinase inhibitor AT7519 is a human RORγt agonist.

Authors: Karaś, Kaja, Pastwińska, Joanna, Sałkowska, Anna, Karwaciak, Iwona, Bachorz, Rafał A, Ratajewski, Marcin

Year: 2025

Venue: Immunology and cell biology

DOI: https://doi.org/10.1111/imcb.12851

Paper Immunotherapies for advanced hepatocellular carcinoma.

Sun, Li-Yang, Zhang, Kang-Jun, Xie, Ya-Ming, Liu, Jun-Wei, Xiao, Zun-Qiang · 2023 · Frontiers in pharmacology · DOI

Full title: Immunotherapies for advanced hepatocellular carcinoma.

Authors: Sun, Li-Yang, Zhang, Kang-Jun, Xie, Ya-Ming, Liu, Jun-Wei, Xiao, Zun-Qiang

Year: 2023

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2023.1138493

Paper Enhancing programmed cell death protein 1 axis inhibition in head and neck squamous cell carcinoma: Combination immunotherapy.

Vathiotis, Ioannis A, Johnson, Jennifer M, Argiris, Athanassios · 2021 · Cancer treatment reviews · DOI

Full title: Enhancing programmed cell death protein 1 axis inhibition in head and neck squamous cell carcinoma: Combination immunotherapy.

Authors: Vathiotis, Ioannis A, Johnson, Jennifer M, Argiris, Athanassios

Year: 2021

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2021.102192

Paper Immune checkpoint Ab enhances the antigen-specific anti-tumor effects by modulating both dendritic cells and regulatory T lymphocytes.

Sun, Nai-Yun, Chen, Yu-Li, Lin, Han-Wei, Chiang, Ying-Cheng, Chang, Chi-Fang, Tai, Yi-Jou, Chen, Chi-An, Sun, Wei-Zen, Chien, Chung-Liang, Cheng, Wen-Fang · 2019 · Cancer letters · DOI

Full title: Immune checkpoint Ab enhances the antigen-specific anti-tumor effects by modulating both dendritic cells and regulatory T lymphocytes.

Authors: Sun, Nai-Yun, Chen, Yu-Li, Lin, Han-Wei, Chiang, Ying-Cheng, Chang, Chi-Fang, Tai, Yi-Jou, Chen, Chi-An, Sun, Wei-Zen, Chien, Chung-Liang, Cheng, Wen-Fang

Year: 2019

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2018.11.039

Paper Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial.

Yim, Sun Young, Lee, Sung Hwan, Baek, Seung-Woo, Sohn, Bohwa, Jeong, Yun Seong, Kang, Sang-Hee, Park, Kena, Park, Hyewon, Lee, Sunyoung S, Kaseb, Ahmed O, Park, Young Nyun, Leem, Sun-Hee, Curran, Michael A, Kim, Ji Hoon, Lee, Ju-Seog · 2024 · Clinical and molecular hepatology · DOI

Full title: Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial.

Authors: Yim, Sun Young, Lee, Sung Hwan, Baek, Seung-Woo, Sohn, Bohwa, Jeong, Yun Seong, Kang, Sang-Hee, Park, Kena, Park, Hyewon, Lee, Sunyoung S, Kaseb, Ahmed O, Park, Young Nyun, Leem, Sun-Hee, Curran, Michael A, Kim, Ji Hoon, Lee, Ju-Seog

Year: 2024

Venue: Clinical and molecular hepatology

DOI: https://doi.org/10.3350/cmh.2024.0333

Paper Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy.

Huang, Ching-Hsin, Mendez, Natalie, Echeagaray, Oscar Hernandez, Weeks, Joi, Wang, James, Yao, Shiyin, Blair, Sarah L, Gude, Natalie, Trogler, William C, Carson, Dennis A, Hayashi, Tomoko, Kummel, Andrew C · 2020 · Advanced therapeutics · DOI

Full title: Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy.

Authors: Huang, Ching-Hsin, Mendez, Natalie, Echeagaray, Oscar Hernandez, Weeks, Joi, Wang, James, Yao, Shiyin, Blair, Sarah L, Gude, Natalie, Trogler, William C, Carson, Dennis A, Hayashi, Tomoko, Kummel, Andrew C

Year: 2020

Venue: Advanced therapeutics

DOI: https://doi.org/10.1002/adtp.201900200

Paper Combination targeted and immune therapy in the treatment of advanced melanoma: a valid treatment option for patients?

Bari, Shahla, Muzaffar, Jameel, Eroglu, Zeynep · 2022 · Therapeutic advances in medical oncology · DOI

Full title: Combination targeted and immune therapy in the treatment of advanced melanoma: a valid treatment option for patients?

Authors: Bari, Shahla, Muzaffar, Jameel, Eroglu, Zeynep

Year: 2022

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359221090306

Paper Unique Cytologic Features of Thyroiditis Caused by Immune Checkpoint Inhibitor Therapy for Malignant Melanoma.

Angell, Trevor E, Min, Le, Wieczorek, Tad J, Hodi, F Stephen · 2018 · Genes & diseases · DOI

Full title: Unique Cytologic Features of Thyroiditis Caused by Immune Checkpoint Inhibitor Therapy for Malignant Melanoma.

Authors: Angell, Trevor E, Min, Le, Wieczorek, Tad J, Hodi, F Stephen

Year: 2018

Venue: Genes & diseases

DOI: https://doi.org/10.1016/j.gendis.2017.11.002

Paper Combining nanomedicine and immune checkpoint therapy for cancer immunotherapy.

Boone, Christine E, Wang, Lu, Gautam, Aayushma, Newton, Isabel G, Steinmetz, Nicole F · 2022 · Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · DOI

Full title: Combining nanomedicine and immune checkpoint therapy for cancer immunotherapy.

Authors: Boone, Christine E, Wang, Lu, Gautam, Aayushma, Newton, Isabel G, Steinmetz, Nicole F

Year: 2022

Venue: Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

DOI: https://doi.org/10.1002/wnan.1739

Paper Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop.

Berraondo, Pedro, Ochoa, María Carmen, Rodriguez-Ruiz, María Esperanza, Minute, Luna, Lasarte, Juan José, Melero, Ignacio · 2016 · Cancer research · DOI

Full title: Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop.

Authors: Berraondo, Pedro, Ochoa, María Carmen, Rodriguez-Ruiz, María Esperanza, Minute, Luna, Lasarte, Juan José, Melero, Ignacio

Year: 2016

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-15-3279

Paper Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.

Wang, Daniel Y, Salem, Joe-Elie, Cohen, Justine V, Chandra, Sunandana, Menzer, Christian, Ye, Fei, Zhao, Shilin, Das, Satya, Beckermann, Kathryn E, Ha, Lisa, Rathmell, W Kimryn, Ancell, Kristin K, Balko, Justin M, Bowman, Caitlin, Davis, Elizabeth J, Chism, David D, Horn, Leora, Long, Georgina V, Carlino, Matteo S, Lebrun-Vignes, Benedicte, Eroglu, Zeynep, Hassel, Jessica C, Menzies, Alexander M, Sosman, Jeffrey A, Sullivan, Ryan J, Moslehi, Javid J, Johnson, Douglas B · 2018 · JAMA oncology · DOI

Full title: Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.

Authors: Wang, Daniel Y, Salem, Joe-Elie, Cohen, Justine V, Chandra, Sunandana, Menzer, Christian, Ye, Fei, Zhao, Shilin, Das, Satya, Beckermann, Kathryn E, Ha, Lisa, Rathmell, W Kimryn, Ancell, Kristin K, Balko, Justin M, Bowman, Caitlin, Davis, Elizabeth J, Chism, David D, Horn, Leora, Long, Georgina V, Carlino, Matteo S, Lebrun-Vignes, Benedicte, Eroglu, Zeynep, Hassel, Jessica C, Menzies, Alexander M, Sosman, Jeffrey A, Sullivan, Ryan J, Moslehi, Javid J, Johnson, Douglas B

Year: 2018

Venue: JAMA oncology

DOI: https://doi.org/10.1001/jamaoncol.2018.3923

Paper Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical models

Ghosh, Arnab, Michel, Judith, Dong, Lauren, Suek, Nathan, Zhong, Hong, Budhu, Sadna, Henau, Olivier De, Wolchok, Jedd D., Merghoub, Taha · 2019 · Experimental and Molecular Therapeutics · DOI

Full title: Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical models

Authors: Ghosh, Arnab, Michel, Judith, Dong, Lauren, Suek, Nathan, Zhong, Hong, Budhu, Sadna, Henau, Olivier De, Wolchok, Jedd D., Merghoub, Taha

Year: 2019

Venue: Experimental and Molecular Therapeutics

DOI: https://doi.org/10.1158/1538-7445.sabcs18-4843

Paper Novel therapeutic strategies for non-small cell lung cancer: Combination therapies with immune checkpoint inhibitors (Review).

Ma, Shengyao, Hu, Ruixin, Xue, Xiaobin, Qu, Meihua, Sun, Guoping · 2025 · Oncology letters · DOI

Full title: Novel therapeutic strategies for non-small cell lung cancer: Combination therapies with immune checkpoint inhibitors (Review).

Authors: Ma, Shengyao, Hu, Ruixin, Xue, Xiaobin, Qu, Meihua, Sun, Guoping

Year: 2025

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2025.15170

Paper The co-inhibitory immune checkpoint proteins B7-H1(PD-L1) and B7-H4 in high grade glioma: From bench to bedside.

Qi, Ying, Huang, Xiaoming, Ji, Chunxia, Wang, Chaojun, Yao, Yu · 2024 · Translational oncology · DOI

Full title: The co-inhibitory immune checkpoint proteins B7-H1(PD-L1) and B7-H4 in high grade glioma: From bench to bedside.

Authors: Qi, Ying, Huang, Xiaoming, Ji, Chunxia, Wang, Chaojun, Yao, Yu

Year: 2024

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2023.101793

Paper Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

Holmgaard, Rikke B, Zamarin, Dmitriy, Munn, David H, Wolchok, Jedd D, Allison, James P · 2013 · The Journal of experimental medicine · DOI

Full title: Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

Authors: Holmgaard, Rikke B, Zamarin, Dmitriy, Munn, David H, Wolchok, Jedd D, Allison, James P

Year: 2013

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20130066

Paper DSP-7888, a Novel Cocktail Design of WT1 Peptide Vaccine, and Its Combinational Immunotherapy with Immune Checkpoint-Blocking Antibody Against PD-1

Masashi Goto, Megumi Nakamura, Natsuko Suginobe, H. Takasu, Yosuke Takanashi, H. Ban, C. Li · 2016 · Blood · DOI

Full title: DSP-7888, a Novel Cocktail Design of WT1 Peptide Vaccine, and Its Combinational Immunotherapy with Immune Checkpoint-Blocking Antibody Against PD-1

Authors: Masashi Goto, Megumi Nakamura, Natsuko Suginobe, H. Takasu, Yosuke Takanashi, H. Ban, C. Li

Year: 2016

Venue: Blood

DOI: https://doi.org/10.1182/blood.v128.22.4715.4715

Paper Neoadjuvant immunotherapy improves outlook in high‐risk melanoma

M. Nierengarten · 2023 · Cancer · DOI

Full title: Neoadjuvant immunotherapy improves outlook in high‐risk melanoma

Authors: M. Nierengarten

Year: 2023

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.34884

Paper Acute rhabdomyolysis with severe polymyositis following ipilimumab-nivolumab treatment in a cancer patient with elevated anti-striated muscle antibody.

Bilen, Mehmet Asim, Subudhi, Sumit K, Gao, Jianjun, Tannir, Nizar M, Tu, Shi-Ming, Sharma, Padmanee · 2016 · Journal for immunotherapy of cancer · DOI

Full title: Acute rhabdomyolysis with severe polymyositis following ipilimumab-nivolumab treatment in a cancer patient with elevated anti-striated muscle antibody.

Authors: Bilen, Mehmet Asim, Subudhi, Sumit K, Gao, Jianjun, Tannir, Nizar M, Tu, Shi-Ming, Sharma, Padmanee

Year: 2016

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-016-0139-8

Paper Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy.

Rouanet, Jacques, Benboubker, Valentin, Akil, Hussein, Hennino, Ana, Auzeloux, Philippe, Besse, Sophie, Pereira, Bruno, Delorme, Solène, Mansard, Sandrine, D'Incan, Michel, Degoul, Françoise, Rouzaire, Paul-Olivier · 2020 · Cancer immunology, immunotherapy : CII · DOI

Full title: Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy.

Authors: Rouanet, Jacques, Benboubker, Valentin, Akil, Hussein, Hennino, Ana, Auzeloux, Philippe, Besse, Sophie, Pereira, Bruno, Delorme, Solène, Mansard, Sandrine, D'Incan, Michel, Degoul, Françoise, Rouzaire, Paul-Olivier

Year: 2020

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02606-8

Paper Prospects for TIM3-Targeted Antitumor Immunotherapy.

Ngiow, Shin Foong, Teng, Michele W L, Smyth, Mark J · 2011 · Cancer research · DOI

Full title: Prospects for TIM3-Targeted Antitumor Immunotherapy.

Authors: Ngiow, Shin Foong, Teng, Michele W L, Smyth, Mark J

Year: 2011

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-11-1487

Paper Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor.

Callahan, Margaret K, Masters, Gregg, Pratilas, Christine A, Ariyan, Charlotte, Katz, Jessica, Kitano, Shigehisa, Russell, Valerie, Gordon, Ruth Ann, Vyas, Shachi, Yuan, Jianda, Gupta, Ashok, Wigginton, Jon M, Rosen, Neal, Merghoub, Taha, Jure-Kunkel, Maria, Wolchok, Jedd D · 2014 · Cancer immunology research · DOI

Full title: Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor.

Authors: Callahan, Margaret K, Masters, Gregg, Pratilas, Christine A, Ariyan, Charlotte, Katz, Jessica, Kitano, Shigehisa, Russell, Valerie, Gordon, Ruth Ann, Vyas, Shachi, Yuan, Jianda, Gupta, Ashok, Wigginton, Jon M, Rosen, Neal, Merghoub, Taha, Jure-Kunkel, Maria, Wolchok, Jedd D

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0160

Paper Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade.

Arias-Badia, Marcel, Pai, Chien-Chun Steven, Lwin, Yee May, Chen, PeiXi, Srinath, Aahir, Tanaka, Miho, Musser, Emily, Goodearl, Andrew, Gorman, Jacob V, Ritacco, Wendy, Fong, Lawrence · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade.

Authors: Arias-Badia, Marcel, Pai, Chien-Chun Steven, Lwin, Yee May, Chen, PeiXi, Srinath, Aahir, Tanaka, Miho, Musser, Emily, Goodearl, Andrew, Gorman, Jacob V, Ritacco, Wendy, Fong, Lawrence

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-010566

Paper Metastatic Melanoma: Recent Therapeutic Progress and Future Perspectives.

Malissen, Nausicaa, Grob, Jean-Jacques · 2018 · Drugs · DOI

Full title: Metastatic Melanoma: Recent Therapeutic Progress and Future Perspectives.

Authors: Malissen, Nausicaa, Grob, Jean-Jacques

Year: 2018

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-018-0945-z

Paper The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors.

Joachim, Laura, Göttert, Sascha, Sax, Anna, Steiger, Katja, Neuhaus, Klaus, Heinrich, Paul, Fan, Kaiji, Orberg, Erik Thiele, Kleigrewe, Karin, Ruland, Jürgen, Bassermann, Florian, Herr, Wolfgang, Posch, Christian, Heidegger, Simon, Poeck, Hendrik · 2023 · EBioMedicine · DOI

Full title: The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors.

Authors: Joachim, Laura, Göttert, Sascha, Sax, Anna, Steiger, Katja, Neuhaus, Klaus, Heinrich, Paul, Fan, Kaiji, Orberg, Erik Thiele, Kleigrewe, Karin, Ruland, Jürgen, Bassermann, Florian, Herr, Wolfgang, Posch, Christian, Heidegger, Simon, Poeck, Hendrik

Year: 2023

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2023.104834

Paper Cure in Advanced Renal Cell Cancer: Is It an Achievable Goal?

Sabanathan, Dhanusha, Park, John J, Marquez, Manuel, Francisco, Louise, Byrne, Natalie, Gurney, Howard · 2017 · The oncologist · DOI

Full title: Cure in Advanced Renal Cell Cancer: Is It an Achievable Goal?

Authors: Sabanathan, Dhanusha, Park, John J, Marquez, Manuel, Francisco, Louise, Byrne, Natalie, Gurney, Howard

Year: 2017

Venue: The oncologist

DOI: https://doi.org/10.1634/theoncologist.2017-0159

Paper Immunotherapy for Gastric Cancer: A Focus on Immune Checkpoints.

Alsina, Maria, Moehler, Markus, Hierro, Cinta, Guardeño, Raquel, Tabernero, Josep · 2016 · Targeted oncology · DOI

Full title: Immunotherapy for Gastric Cancer: A Focus on Immune Checkpoints.

Authors: Alsina, Maria, Moehler, Markus, Hierro, Cinta, Guardeño, Raquel, Tabernero, Josep

Year: 2016

Venue: Targeted oncology

DOI: https://doi.org/10.1007/s11523-016-0421-1

Paper Immune checkpoint inhibitors: therapeutic advances in melanoma.

Márquez-Rodas, Ivan, Cerezuela, Pablo, Soria, Ainara, Berrocal, Alfonso, Riso, Aldo, González-Cao, María, Martín-Algarra, Salvador · 2015 · Annals of translational medicine · DOI

Full title: Immune checkpoint inhibitors: therapeutic advances in melanoma.

Authors: Márquez-Rodas, Ivan, Cerezuela, Pablo, Soria, Ainara, Berrocal, Alfonso, Riso, Aldo, González-Cao, María, Martín-Algarra, Salvador

Year: 2015

Venue: Annals of translational medicine

DOI: https://doi.org/10.3978/j.issn.2305-5839.2015.10.27

Paper Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma.

Howell, Ashley V, Gebregziabher, Mulugeta, Thiers, Bruce H, Paulos, Chrystal M, Wrangle, John M, Hunt, Kelly J, Wallace, Kristin · 2021 · Journal of geriatric oncology · DOI

Full title: Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma.

Authors: Howell, Ashley V, Gebregziabher, Mulugeta, Thiers, Bruce H, Paulos, Chrystal M, Wrangle, John M, Hunt, Kelly J, Wallace, Kristin

Year: 2021

Venue: Journal of geriatric oncology

DOI: https://doi.org/10.1016/j.jgo.2020.09.023

Paper Immunotherapy in Urothelial Cancer: Recent Results and Future Perspectives.

Farina, Matthew S, Lundgren, Kevin T, Bellmunt, Joaquim · 2017 · Drugs · DOI

Full title: Immunotherapy in Urothelial Cancer: Recent Results and Future Perspectives.

Authors: Farina, Matthew S, Lundgren, Kevin T, Bellmunt, Joaquim

Year: 2017

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-017-0748-7

Paper Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles

Jun Deng, Hui-Min Ke · 2022 · Oncoimmunology · DOI

Full title: Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles

Authors: Jun Deng, Hui-Min Ke

Year: 2022

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402x.2022.2152635

Paper Immune checkpoint inhibitors and targeted therapies for metastatic melanoma: A network meta-analysis.

Pasquali, Sandro, Chiarion-Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone · 2017 · Cancer treatment reviews · DOI

Full title: Immune checkpoint inhibitors and targeted therapies for metastatic melanoma: A network meta-analysis.

Authors: Pasquali, Sandro, Chiarion-Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone

Year: 2017

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2017.01.006

Paper Tumor mutational burden in non-small cell lung cancer-the pathologist's point of view.

Penault-Llorca, Frédérique, Radosevic-Robin, Nina · 2018 · Translational lung cancer research · DOI

Full title: Tumor mutational burden in non-small cell lung cancer-the pathologist's point of view.

Authors: Penault-Llorca, Frédérique, Radosevic-Robin, Nina

Year: 2018

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr.2018.09.26

Paper - **DOI:** 10.1158/1538-7445.panca22-c013 - **Authors:** Noah Cheng, N. Markosyan, R. Vonderheide - **Year:** 2022 - **Journal:** Cancer Research

Noah Cheng, N. Markosyan, R. Vonderheide · 2022 · Cancer Research · DOI

Full title: - **DOI:** 10.1158/1538-7445.panca22-c013 - **Authors:** Noah Cheng, N. Markosyan, R. Vonderheide - **Year:** 2022 - **Journal:** Cancer Research

Authors: Noah Cheng, N. Markosyan, R. Vonderheide

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.panca22-c013

Paper Side effect management during immune checkpoint blockade using CTLA-4 and PD-1 antibodies for metastatic melanoma - an update.

Kähler, Katharina C, Hassel, Jessica C, Heinzerling, Lucie, Loquai, Carmen, Thoms, Kai-Martin, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf, committee on “Cutaneous Adverse Events“ of the German Working Group for Dermatological Oncology (Arbeitsgemeinschaft Dermatologische Onkologie, ADO) · 2020 · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · DOI

Full title: Side effect management during immune checkpoint blockade using CTLA-4 and PD-1 antibodies for metastatic melanoma - an update.

Authors: Kähler, Katharina C, Hassel, Jessica C, Heinzerling, Lucie, Loquai, Carmen, Thoms, Kai-Martin, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf, committee on “Cutaneous Adverse Events“ of the German Working Group for Dermatological Oncology (Arbeitsgemeinschaft Dermatologische Onkologie, ADO)

Year: 2020

Venue: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

DOI: https://doi.org/10.1111/ddg.14128

Paper Very Late Recurrence of Clear Cell Renal Cell Carcinoma With Pancreatic and Hepatic Metastases Showing Durable Response to Dual Checkpoint Blockade.

Ito, Fumihiro, Kobayashi, Koki, Hayashi, Gaku, Kamijo, Shunsuke, Fujita, Takashi · 2026 · Clinical case reports · DOI

Full title: Very Late Recurrence of Clear Cell Renal Cell Carcinoma With Pancreatic and Hepatic Metastases Showing Durable Response to Dual Checkpoint Blockade.

Authors: Ito, Fumihiro, Kobayashi, Koki, Hayashi, Gaku, Kamijo, Shunsuke, Fujita, Takashi

Year: 2026

Venue: Clinical case reports

DOI: https://doi.org/10.1002/ccr3.71852

Paper Clinical Trials in Metastatic Uveal Melanoma: Immunotherapy.

Orloff, Marlana · 2021 · Ocular oncology and pathology · DOI

Full title: Clinical Trials in Metastatic Uveal Melanoma: Immunotherapy.

Authors: Orloff, Marlana

Year: 2021

Venue: Ocular oncology and pathology

DOI: https://doi.org/10.1159/000513336

Paper Immunotherapy in Advanced Non-Small Cell Lung Cancer

Joy Huang, K. Reckamp · 2020 · Seminars in Respiratory and Critical Care Medicine · DOI

Full title: Immunotherapy in Advanced Non-Small Cell Lung Cancer

Authors: Joy Huang, K. Reckamp

Year: 2020

Venue: Seminars in Respiratory and Critical Care Medicine

DOI: https://doi.org/10.1055/s-0040-1710077

Paper Rapid and Complete Response to Combination Anti-CTLA-4 and Anti-PD-1 Checkpoint Inhibitor Therapy in a Patient With Stage IV Refractory End-stage Epithelioid Sarcoma: A Case Report.

Pecora, Andrew, Halpern, Steven, Weber, Melinda, Paleoudis, Elli G, Panush, David, Patterson, Francis, Toretsky, Jeffery · 2020 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Rapid and Complete Response to Combination Anti-CTLA-4 and Anti-PD-1 Checkpoint Inhibitor Therapy in a Patient With Stage IV Refractory End-stage Epithelioid Sarcoma: A Case Report.

Authors: Pecora, Andrew, Halpern, Steven, Weber, Melinda, Paleoudis, Elli G, Panush, David, Patterson, Francis, Toretsky, Jeffery

Year: 2020

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000332

Paper Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer.

Suarez-Carmona, Meggy, Halama, Niels · 2024 · Trends in cancer · DOI

Full title: Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer.

Authors: Suarez-Carmona, Meggy, Halama, Niels

Year: 2024

Venue: Trends in cancer

DOI: https://doi.org/10.1016/j.trecan.2024.10.006

Paper Immuno-pharmacodynamics for evaluating mechanism of action and developing immunotherapy combinations.

Parchment, Ralph E, Voth, Andrea Regier, Doroshow, James H, Berzofsky, Jay A · 2016 · Seminars in oncology · DOI

Full title: Immuno-pharmacodynamics for evaluating mechanism of action and developing immunotherapy combinations.

Authors: Parchment, Ralph E, Voth, Andrea Regier, Doroshow, James H, Berzofsky, Jay A

Year: 2016

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2016.06.008

Paper Scientific Rationale for Combination Immunotherapy of Hepatocellular Carcinoma with Anti-PD-1/PD-L1 and Anti-CTLA-4 Antibodies.

Kudo, Masatoshi · 2019 · Liver cancer · DOI

Full title: Scientific Rationale for Combination Immunotherapy of Hepatocellular Carcinoma with Anti-PD-1/PD-L1 and Anti-CTLA-4 Antibodies.

Authors: Kudo, Masatoshi

Year: 2019

Venue: Liver cancer

DOI: https://doi.org/10.1159/000503254

Paper Advancing immunotherapy for early-stage triple-negative breast cancer

Cosimo, Serena Di · 2020 · The Lancet · DOI

Full title: Advancing immunotherapy for early-stage triple-negative breast cancer

Authors: Cosimo, Serena Di

Year: 2020

Venue: The Lancet

DOI: https://doi.org/10.1016/s0140-6736(20)31962-0

Paper Future Research Goals in Immunotherapy.

Hulett, Tyler W, Fox, Bernard A, Messenheimer, David J, Marwitz, Sebastian, Moudgil, Tarsem, Afentoulis, Michael E, Wegman, Keith W, Ballesteros-Merino, Carmen, Jensen, Shawn M · 2019 · Surgical oncology clinics of North America · DOI

Full title: Future Research Goals in Immunotherapy.

Authors: Hulett, Tyler W, Fox, Bernard A, Messenheimer, David J, Marwitz, Sebastian, Moudgil, Tarsem, Afentoulis, Michael E, Wegman, Keith W, Ballesteros-Merino, Carmen, Jensen, Shawn M

Year: 2019

Venue: Surgical oncology clinics of North America

DOI: https://doi.org/10.1016/j.soc.2019.02.006

Paper Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.

Olson, Brian M, Jankowska-Gan, Ewa, Becker, Jordan T, Vignali, Dario A A, Burlingham, William J, McNeel, Douglas G · 2012 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.

Authors: Olson, Brian M, Jankowska-Gan, Ewa, Becker, Jordan T, Vignali, Dario A A, Burlingham, William J, McNeel, Douglas G

Year: 2012

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.1201744

Paper Combination immunotherapy with anti-CTLA-4 and interleukin-2 redirects regulatory T cells into tumor-draining lymph nodes and expands anti-tumor CD8+ T cells in the tumor microenvironment

Broucek, Joseph, Hughes, Tasha M., Huelsmann, Erica, Lusciks, Eugene, Hill, G. R., Zayas, Janet, Poshepny, Joseph L, Ruby, Carl E., Kohlhapp, Frederick J., Zloza, Andrew, Kaufman, Howard L. · 2014 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Combination immunotherapy with anti-CTLA-4 and interleukin-2 redirects regulatory T cells into tumor-draining lymph nodes and expands anti-tumor CD8+ T cells in the tumor microenvironment

Authors: Broucek, Joseph, Hughes, Tasha M., Huelsmann, Erica, Lusciks, Eugene, Hill, G. R., Zayas, Janet, Poshepny, Joseph L, Ruby, Carl E., Kohlhapp, Frederick J., Zloza, Andrew, Kaufman, Howard L.

Year: 2014

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/2051-1426-2-s3-p97

Paper Engineering nanoparticles to locally activate T cells in the tumor microenvironment

Wang, Dangge, Wang, Tingting, Yu, Haijun, Feng, Bing, Zhou, Lei, Zhou, Fangyuan, Hou, Bo, Zhang, Hanwu, Luo, Min, Li, Yaping · 2019 · Science Immunology · DOI

Full title: Engineering nanoparticles to locally activate T cells in the tumor microenvironment

Authors: Wang, Dangge, Wang, Tingting, Yu, Haijun, Feng, Bing, Zhou, Lei, Zhou, Fangyuan, Hou, Bo, Zhang, Hanwu, Luo, Min, Li, Yaping

Year: 2019

Venue: Science Immunology

DOI: https://doi.org/10.1126/sciimmunol.aau6584

Paper Safety of immune checkpoint inhibitors in Chinese patients with melanoma.

Wen, Xizhi, Wang, Yao, Ding, Ya, Li, Dandan, Li, Jingjing, Guo, Yiqun, Peng, Ruiqing, Zhao, Jingjing, Zhang, Xing, Zhang, Xiao-Shi · 2016 · Melanoma research · DOI

Full title: Safety of immune checkpoint inhibitors in Chinese patients with melanoma.

Authors: Wen, Xizhi, Wang, Yao, Ding, Ya, Li, Dandan, Li, Jingjing, Guo, Yiqun, Peng, Ruiqing, Zhao, Jingjing, Zhang, Xing, Zhang, Xiao-Shi

Year: 2016

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000256

Paper XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.

Jenkins, Kurt A, Park, Miso, Pederzoli-Ribeil, Magali, Eskiocak, Ugur, Johnson, Parker, Guzman, Wilson, McLaughlin, Megan, Moore-Lai, Deborah, O'Toole, Caitlin, Liu, Zhen, Nicholson, Benjamin, Flesch, Veronica, Qiu, Huawei, Clackson, Tim, O'Hagan, Ronan C, Rodeck, Ulrich, Karow, Margaret, O'Neil, Jennifer, Williams, John C · 2023 · Journal for immunotherapy of cancer · DOI

Full title: XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.

Authors: Jenkins, Kurt A, Park, Miso, Pederzoli-Ribeil, Magali, Eskiocak, Ugur, Johnson, Parker, Guzman, Wilson, McLaughlin, Megan, Moore-Lai, Deborah, O'Toole, Caitlin, Liu, Zhen, Nicholson, Benjamin, Flesch, Veronica, Qiu, Huawei, Clackson, Tim, O'Hagan, Ronan C, Rodeck, Ulrich, Karow, Margaret, O'Neil, Jennifer, Williams, John C

Year: 2023

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2023-007785

Paper A lipid/PLGA nanocomplex to reshape tumor immune microenvironment for colon cancer therapy

Zhang, Nan, Sun, Qiqi, Li, Junhua, Li, Jing, Tang, Lei, Zhao, Quan, Pu, Yuji, Liang, Gaofeng, He, Bin, Gao, Wenxia, Chen, Jianlin · 2024 · Regenerative Biomaterials · DOI

Full title: A lipid/PLGA nanocomplex to reshape tumor immune microenvironment for colon cancer therapy

Authors: Zhang, Nan, Sun, Qiqi, Li, Junhua, Li, Jing, Tang, Lei, Zhao, Quan, Pu, Yuji, Liang, Gaofeng, He, Bin, Gao, Wenxia, Chen, Jianlin

Year: 2024

Venue: Regenerative Biomaterials

DOI: https://doi.org/10.1093/rb/rbae036

Paper Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Wang, Minyu, Zadeh, Soroor Hediyeh, Pizzolla, Angela, Thia, Kevin, Gyorki, David, McArthur, Grant A., Scolyer, Richard A., Long, Georgina V., Wilmott, James S., Andrews, Miles C., Au‐Yeung, George, Weppler, Ali, Sandhu, Shahneen, Trapani, Joseph A., Davis, Melissa J., Neeson, Paul J. · 2022 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Authors: Wang, Minyu, Zadeh, Soroor Hediyeh, Pizzolla, Angela, Thia, Kevin, Gyorki, David, McArthur, Grant A., Scolyer, Richard A., Long, Georgina V., Wilmott, James S., Andrews, Miles C., Au‐Yeung, George, Weppler, Ali, Sandhu, Shahneen, Trapani, Joseph A., Davis, Melissa J., Neeson, Paul J.

Year: 2022

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2021-004095

Paper Educational Review: Clinical Application of Immune Checkpoint Blockade for the Treatment of Melanoma.

Su, David, Kluger, Harriet, Olino, Kelly · 2024 · Annals of surgical oncology · DOI

Full title: Educational Review: Clinical Application of Immune Checkpoint Blockade for the Treatment of Melanoma.

Authors: Su, David, Kluger, Harriet, Olino, Kelly

Year: 2024

Venue: Annals of surgical oncology

DOI: https://doi.org/10.1245/s10434-023-14587-w

Paper Abstract CT037: Nivolumab plus ipilimumab vs chemotherapy as first-line treatment for advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma: CheckMate 649 biomarker analyses

Janjigian, Yelena Y., Shitara, Kohei, Ajani, Jaffer A., Moehler, Markus, Yao, Jin, Shen, Lin, Garrido, Marcelo, Gallardo, Carlos, Wyrwicz, Lucjan, Yamaguchi, Kensei, Skoczylas, Tomasz, Bragagnoli, Arinilda Campos, Liu, Tianshu, Schenker, Michael, Yañez, Patricio, Kowalyszyn, Rubén Dario, Karamouzis, Michalis V., Zander, Thomas, Feeney, Kynan, Elimova, Elena, Nathani, Raheel, Novosiadly, Ruslan D., Lei, Ming · 2023 · Cancer Research · DOI

Full title: Abstract CT037: Nivolumab plus ipilimumab vs chemotherapy as first-line treatment for advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma: CheckMate 649 biomarker analyses

Authors: Janjigian, Yelena Y., Shitara, Kohei, Ajani, Jaffer A., Moehler, Markus, Yao, Jin, Shen, Lin, Garrido, Marcelo, Gallardo, Carlos, Wyrwicz, Lucjan, Yamaguchi, Kensei, Skoczylas, Tomasz, Bragagnoli, Arinilda Campos, Liu, Tianshu, Schenker, Michael, Yañez, Patricio, Kowalyszyn, Rubén Dario, Karamouzis, Michalis V., Zander, Thomas, Feeney, Kynan, Elimova, Elena, Nathani, Raheel, Novosiadly, Ruslan D., Lei, Ming

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-ct037

Paper Dahuang Fuzi Baijiang decoction restricts progenitor to terminally exhausted T cell differentiation in colorectal cancer

Xu, Yihua, Wang, Hao, Wang, Tao, Chen, Chunhui, Sun, Ruibo, Yao, Wanyu, Ma, Ye, Zhang, Qingyuan, Wu, Liyi, Zeng, Shanmei, Sun, Xuegang · 2022 · Cancer Science · DOI

Full title: Dahuang Fuzi Baijiang decoction restricts progenitor to terminally exhausted T cell differentiation in colorectal cancer

Authors: Xu, Yihua, Wang, Hao, Wang, Tao, Chen, Chunhui, Sun, Ruibo, Yao, Wanyu, Ma, Ye, Zhang, Qingyuan, Wu, Liyi, Zeng, Shanmei, Sun, Xuegang

Year: 2022

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.15311

Paper [Combined Regimens in Immunotherapy].

Melichar, B, Spisarová, M · 2017 · Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti · DOI

Full title: [Combined Regimens in Immunotherapy].

Authors: Melichar, B, Spisarová, M

Year: 2017

Venue: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

DOI: https://doi.org/10.14735/amko20173S45

Paper pH-dependent dissociation from CTLA-4 in early endosomes improves both safety and antitumor activity of anti-CTLA-4 antibodies.

Zhang, Meiyu, Li, Jinmei, Yan, Kepeng, Zhou, Haoyue, Mei, Song, Wang, Benyu, Li, Dongyang, Du, Xuexiang, Liu, Mingyue, Zhang, Peng, Fields, James K, Ye, Lei, Zheng, Pan, Liu, Yang, Lenardo, Michael J, Zhang, Yan · 2025 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: pH-dependent dissociation from CTLA-4 in early endosomes improves both safety and antitumor activity of anti-CTLA-4 antibodies.

Authors: Zhang, Meiyu, Li, Jinmei, Yan, Kepeng, Zhou, Haoyue, Mei, Song, Wang, Benyu, Li, Dongyang, Du, Xuexiang, Liu, Mingyue, Zhang, Peng, Fields, James K, Ye, Lei, Zheng, Pan, Liu, Yang, Lenardo, Michael J, Zhang, Yan

Year: 2025

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2422731122

Paper Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.

Sharma, Anu, Subudhi, Sumit K, Blando, Jorge, Scutti, Jorge, Vence, Luis, Wargo, Jennifer, Allison, James P, Ribas, Antoni, Sharma, Padmanee · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.

Authors: Sharma, Anu, Subudhi, Sumit K, Blando, Jorge, Scutti, Jorge, Vence, Luis, Wargo, Jennifer, Allison, James P, Ribas, Antoni, Sharma, Padmanee

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0762

Paper A Case of Immunotherapy-Induced Colitis Complicated by Perforation and Treated with Infliximab Postoperatively.

Delasos, Lukas, Desai, Aakash, Lopetegui Lia, Nerea, Kethireddy, Nikhila, Ray, Carolyn · 2019 · Case reports in oncological medicine · DOI

Full title: A Case of Immunotherapy-Induced Colitis Complicated by Perforation and Treated with Infliximab Postoperatively.

Authors: Delasos, Lukas, Desai, Aakash, Lopetegui Lia, Nerea, Kethireddy, Nikhila, Ray, Carolyn

Year: 2019

Venue: Case reports in oncological medicine

DOI: https://doi.org/10.1155/2019/9069354

Paper Antitumor Immunity Augmented by Combining Radiofrequency Ablation with Anti-CTLA-4 Therapy in a Subcutaneous Murine Hepatoma Model.

Zhang, Liang, Xu, Lichao, Wang, Ying, Liu, Xiaofei, Zhang, Mingming, Li, Wentao · 2020 · Journal of vascular and interventional radiology : JVIR · DOI

Full title: Antitumor Immunity Augmented by Combining Radiofrequency Ablation with Anti-CTLA-4 Therapy in a Subcutaneous Murine Hepatoma Model.

Authors: Zhang, Liang, Xu, Lichao, Wang, Ying, Liu, Xiaofei, Zhang, Mingming, Li, Wentao

Year: 2020

Venue: Journal of vascular and interventional radiology : JVIR

DOI: https://doi.org/10.1016/j.jvir.2020.01.022

Paper [Checkpoint inhibitors-induced hypophysitis].

du Payrat, Juliette Abeillon, Cugnet-Anceau, Christine, Maillet, Denis, Levy, Manon, Raverot, Gérald, Disse, Emmanuel, Borson-Chazot, Françoise · 2020 · Bulletin du cancer · DOI

Full title: [Checkpoint inhibitors-induced hypophysitis].

Authors: du Payrat, Juliette Abeillon, Cugnet-Anceau, Christine, Maillet, Denis, Levy, Manon, Raverot, Gérald, Disse, Emmanuel, Borson-Chazot, Françoise

Year: 2020

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2020.01.012

Paper Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell Infiltration.

Ock, Chan-Young, Keam, Bhumsuk, Kim, Sehui, Lee, Ju-Seog, Kim, Miso, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Heo, Dae Seog · 2016 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell Infiltration.

Authors: Ock, Chan-Young, Keam, Bhumsuk, Kim, Sehui, Lee, Ju-Seog, Kim, Miso, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Heo, Dae Seog

Year: 2016

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-15-2834

Paper Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.

Stohl, William, Yu, Ning, Chalmers, Samantha A, Putterman, Chaim, Jacob, Chaim O · 2019 · Lupus science & medicine · DOI

Full title: Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.

Authors: Stohl, William, Yu, Ning, Chalmers, Samantha A, Putterman, Chaim, Jacob, Chaim O

Year: 2019

Venue: Lupus science & medicine

DOI: https://doi.org/10.1136/lupus-2018-000313

Paper Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update.

Kudo, Masatoshi · 2017 · Oncology · DOI

Full title: Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update.

Authors: Kudo, Masatoshi

Year: 2017

Venue: Oncology

DOI: https://doi.org/10.1159/000481245

Paper Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma

Kiyokawa, Juri, Kawamura, Yoichiro, Ghouse, Shanawaz M., Acar, Simge, Barçın, Erinç, Martínez‐Quintanilla, Jordi, Martuza, Robert L., Alemany, Ramón, Rabkin, Samuel D., Shah, Khalid, Wakimoto, Hiroaki · 2020 · Clinical Cancer Research · DOI

Full title: Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma

Authors: Kiyokawa, Juri, Kawamura, Yoichiro, Ghouse, Shanawaz M., Acar, Simge, Barçın, Erinç, Martínez‐Quintanilla, Jordi, Martuza, Robert L., Alemany, Ramón, Rabkin, Samuel D., Shah, Khalid, Wakimoto, Hiroaki

Year: 2020

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-20-2400

Paper Patient responses to ipilimumab, a novel immunopotentiator for metastatic melanoma: how different are these from conventional treatment responses?

Pennock, Gregory K, Waterfield, William, Wolchok, Jedd D · 2012 · American journal of clinical oncology · DOI

Full title: Patient responses to ipilimumab, a novel immunopotentiator for metastatic melanoma: how different are these from conventional treatment responses?

Authors: Pennock, Gregory K, Waterfield, William, Wolchok, Jedd D

Year: 2012

Venue: American journal of clinical oncology

DOI: https://doi.org/10.1097/COC.0b013e318209cda9

Paper An open-label, multicenter, adaptive, phase Ib/II study of QL1706 or QL1604 plus bevacizumab as first-line treatment in patients with advanced hepatocellular carcinoma.

Bi, Feng, Zhang, Yanqiao, Gu, Shanzhi, Guo, Yabing, Xu, Zhongyuan, Hao, Ying, Da, Mingxu, Liu, Chaoying, Pan, Yaozhen, Huang, Yao, Chen, Zhiyu, Wang, Zheng, Wu, Jianbing, Weng, Shangeng, Wang, Yanjun, Zhao, Jun, Yu, Xiaokui, Li, Hui, Xue, Shilin, Kang, Xiaoyan · 2023 · Journal of Clinical Oncology · DOI

Full title: An open-label, multicenter, adaptive, phase Ib/II study of QL1706 or QL1604 plus bevacizumab as first-line treatment in patients with advanced hepatocellular carcinoma.

Authors: Bi, Feng, Zhang, Yanqiao, Gu, Shanzhi, Guo, Yabing, Xu, Zhongyuan, Hao, Ying, Da, Mingxu, Liu, Chaoying, Pan, Yaozhen, Huang, Yao, Chen, Zhiyu, Wang, Zheng, Wu, Jianbing, Weng, Shangeng, Wang, Yanjun, Zhao, Jun, Yu, Xiaokui, Li, Hui, Xue, Shilin, Kang, Xiaoyan

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.16_suppl.4077

Paper Recent Advances of Small Molecular Regulators Targeting G Protein- Coupled Receptors Family for Oncology Immunotherapy.

He, Peng, Zhou, Wenbo, Liu, Mingyao, Chen, Yihua · 2019 · Current topics in medicinal chemistry · DOI

Full title: Recent Advances of Small Molecular Regulators Targeting G Protein- Coupled Receptors Family for Oncology Immunotherapy.

Authors: He, Peng, Zhou, Wenbo, Liu, Mingyao, Chen, Yihua

Year: 2019

Venue: Current topics in medicinal chemistry

DOI: https://doi.org/10.2174/1568026619666190628115644

Paper The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.

Zingg, Daniel, Arenas-Ramirez, Natalia, Sahin, Dilara, Rosalia, Rodney A, Antunes, Ana T, Haeusel, Jessica, Sommer, Lukas, Boyman, Onur · 2017 · Cell reports · DOI

Full title: The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.

Authors: Zingg, Daniel, Arenas-Ramirez, Natalia, Sahin, Dilara, Rosalia, Rodney A, Antunes, Ana T, Haeusel, Jessica, Sommer, Lukas, Boyman, Onur

Year: 2017

Venue: Cell reports

DOI: https://doi.org/10.1016/j.celrep.2017.07.007

Paper Immune checkpoint inhibitors in pediatric patients with melanoma: a systematic literature review.

Vyas, Charmy, Moshyk, Andriy, Fusaro, Gina, Zacharoulis, Stergios, Fazeli, Mir Sohail, Gaind, Nishu, Behyan, Shirin, Thakkar, Pratik · 2024 · Melanoma management · DOI

Full title: Immune checkpoint inhibitors in pediatric patients with melanoma: a systematic literature review.

Authors: Vyas, Charmy, Moshyk, Andriy, Fusaro, Gina, Zacharoulis, Stergios, Fazeli, Mir Sohail, Gaind, Nishu, Behyan, Shirin, Thakkar, Pratik

Year: 2024

Venue: Melanoma management

DOI: https://doi.org/10.1080/20450885.2024.2382075

Paper Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier!

Castro, Maria G, Baker, Gregory J, Lowenstein, Pedro R · 2014 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier!

Authors: Castro, Maria G, Baker, Gregory J, Lowenstein, Pedro R

Year: 2014

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-14-0820

Paper Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

de Moel, Emma C, Rozeman, Elisa A, Kapiteijn, Ellen H, Verdegaal, Els M E, Grummels, Annette, Bakker, Jaap A, Huizinga, Tom W J, Haanen, John B, Toes, René E M, van der Woude, Diane · 2019 · Cancer immunology research · DOI

Full title: Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

Authors: de Moel, Emma C, Rozeman, Elisa A, Kapiteijn, Ellen H, Verdegaal, Els M E, Grummels, Annette, Bakker, Jaap A, Huizinga, Tom W J, Haanen, John B, Toes, René E M, van der Woude, Diane

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0245

Paper Abstract C064: Chronic platinum exposure induces cell-intrinsic type1 interferon/STING pathway activation in homologous recombination-deficient pancreatic cancer to drive sensitivity to checkpoint immunotherapy

Ogobuiro, Ifeanyichukwu C., Bianchi, Anna, Caeiro, Lucas D., Amirian, Haleh, Nivelo, Luis, Silva, Iago De Castro, Rajkumar, Karthik, Adams, Andrew, Garrido, Vanessa T., Singh, Samara P., Nagathihalli, Nagaraj S., Merchant, Nipun B., Verdún, Ramiro E., Hosein, Peter J., Datta, Jashodeep · 2024 · Cancer Research · DOI

Full title: Abstract C064: Chronic platinum exposure induces cell-intrinsic type1 interferon/STING pathway activation in homologous recombination-deficient pancreatic cancer to drive sensitivity to checkpoint immunotherapy

Authors: Ogobuiro, Ifeanyichukwu C., Bianchi, Anna, Caeiro, Lucas D., Amirian, Haleh, Nivelo, Luis, Silva, Iago De Castro, Rajkumar, Karthik, Adams, Andrew, Garrido, Vanessa T., Singh, Samara P., Nagathihalli, Nagaraj S., Merchant, Nipun B., Verdún, Ramiro E., Hosein, Peter J., Datta, Jashodeep

Year: 2024

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.panca2023-c064

Paper Programmed cell death ligand-1 expression in tumor and immune cells is associated with better patient outcome and decreased tumor-infiltrating lymphocytes in uveal melanoma.

Zoroquiain, Pablo, Esposito, Evangelina, Logan, Patrick, Aldrees, Sultan, Dias, Ana Beatriz, Mansure, Jose Joao, Santapau, Daniela, Garcia, Ciro, Saornil, Maria Antonia, Belfort Neto, Rubens, Burnier, Miguel N · 2018 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · DOI

Full title: Programmed cell death ligand-1 expression in tumor and immune cells is associated with better patient outcome and decreased tumor-infiltrating lymphocytes in uveal melanoma.

Authors: Zoroquiain, Pablo, Esposito, Evangelina, Logan, Patrick, Aldrees, Sultan, Dias, Ana Beatriz, Mansure, Jose Joao, Santapau, Daniela, Garcia, Ciro, Saornil, Maria Antonia, Belfort Neto, Rubens, Burnier, Miguel N

Year: 2018

Venue: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

DOI: https://doi.org/10.1038/s41379-018-0043-5

Paper TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma.

Reilley, Matthew J, Morrow, Brittany, Ager, Casey R, Liu, Arthur, Hong, David S, Curran, Michael A · 2019 · Journal for immunotherapy of cancer · DOI

Full title: TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma.

Authors: Reilley, Matthew J, Morrow, Brittany, Ager, Casey R, Liu, Arthur, Hong, David S, Curran, Michael A

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0811-x

Paper Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Kim, Victoria M., Blair, Alex B., Lauer, Peter, Foley, Kelly, Che, Xu, Soares, Kevin C., Xia, Tao, Muth, Stephen, Kleponis, Jennifer, Armstrong, Todd D., Wolfgang, Christopher L., Jaffee, Elizabeth M., Brockstedt, Dirk G., Zheng, Lei · 2019 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Authors: Kim, Victoria M., Blair, Alex B., Lauer, Peter, Foley, Kelly, Che, Xu, Soares, Kevin C., Xia, Tao, Muth, Stephen, Kleponis, Jennifer, Armstrong, Todd D., Wolfgang, Christopher L., Jaffee, Elizabeth M., Brockstedt, Dirk G., Zheng, Lei

Year: 2019

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-019-0601-5

Paper Emerging combination immunotherapy strategies for breast cancer: dual immune checkpoint modulation, antibody–drug conjugates and bispecific antibodies

Torres, Evanthia T. Roussos, Emens, Leisha A. · 2021 · Breast Cancer Research and Treatment · DOI

Full title: Emerging combination immunotherapy strategies for breast cancer: dual immune checkpoint modulation, antibody–drug conjugates and bispecific antibodies

Authors: Torres, Evanthia T. Roussos, Emens, Leisha A.

Year: 2021

Venue: Breast Cancer Research and Treatment

DOI: https://doi.org/10.1007/s10549-021-06423-0

Paper Public Adverse Event Data Insights into the Safety of Pembrolizumab in Melanoma Patients.

Schaefer, Anne, Sachpekidis, Christos, Diella, Francesca, Doerks, Anja, Kratz, Anne-Sophie, Meisel, Christian, Jackson, David B, Soldatos, Theodoros G · 2020 · Cancers · DOI

Full title: Public Adverse Event Data Insights into the Safety of Pembrolizumab in Melanoma Patients.

Authors: Schaefer, Anne, Sachpekidis, Christos, Diella, Francesca, Doerks, Anja, Kratz, Anne-Sophie, Meisel, Christian, Jackson, David B, Soldatos, Theodoros G

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12041008

Paper Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Choi, Hyejin, Deng, Jiehui, Li, Shuai, Silk, Tarik, Dong, Lauren, Brea, Elliott J, Houghton, Sean, Redmond, David, Zhong, Hong, Boiarsky, Jonathan, Akbay, Esra A, Smith, Paul D, Merghoub, Taha, Wong, Kwok-Kin, Wolchok, Jedd D · 2019 · Cell reports · DOI

Full title: Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Authors: Choi, Hyejin, Deng, Jiehui, Li, Shuai, Silk, Tarik, Dong, Lauren, Brea, Elliott J, Houghton, Sean, Redmond, David, Zhong, Hong, Boiarsky, Jonathan, Akbay, Esra A, Smith, Paul D, Merghoub, Taha, Wong, Kwok-Kin, Wolchok, Jedd D

Year: 2019

Venue: Cell reports

DOI: https://doi.org/10.1016/j.celrep.2019.03.066

Paper Blockade of CTLA-4 increases anti-tumor response inducing potential of dendritic cell vaccine.

Esmaily, Maryam, Masjedi, Ali, Hallaj, Shahin, Nabi Afjadi, Mohsen, Malakotikhah, Farinaz, Ghani, Sepideh, Ahmadi, Armin, Sojoodi, Mozhdeh, Hassannia, Hadi, Atyabi, Fatemeh, Namdar, Afshin, Azizi, Gholamreza, Ghalamfarsa, Ghasem, Jadidi-Niaragh, Farhad · 2020 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Blockade of CTLA-4 increases anti-tumor response inducing potential of dendritic cell vaccine.

Authors: Esmaily, Maryam, Masjedi, Ali, Hallaj, Shahin, Nabi Afjadi, Mohsen, Malakotikhah, Farinaz, Ghani, Sepideh, Ahmadi, Armin, Sojoodi, Mozhdeh, Hassannia, Hadi, Atyabi, Fatemeh, Namdar, Afshin, Azizi, Gholamreza, Ghalamfarsa, Ghasem, Jadidi-Niaragh, Farhad

Year: 2020

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2020.06.017

Paper Smoking status combined with tumor mutational burden as a prognosis predictor for combination immune checkpoint inhibitor therapy in non-small cell lung cancer.

Sun, Li-Yue, Cen, Wen-Jian, Tang, Wen-Ting, Long, Ya-Kang, Yang, Xin-Hua, Ji, Xiao-Meng, Yang, Jiao-Jiao, Zhang, Ren-Jing, Wang, Fang, Shao, Jian-Yong, Du, Zi-Ming · 2021 · Cancer medicine · DOI

Full title: Smoking status combined with tumor mutational burden as a prognosis predictor for combination immune checkpoint inhibitor therapy in non-small cell lung cancer.

Authors: Sun, Li-Yue, Cen, Wen-Jian, Tang, Wen-Ting, Long, Ya-Kang, Yang, Xin-Hua, Ji, Xiao-Meng, Yang, Jiao-Jiao, Zhang, Ren-Jing, Wang, Fang, Shao, Jian-Yong, Du, Zi-Ming

Year: 2021

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.4197

Paper The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

Blank, Christian U · 2014 · Current opinion in oncology · DOI

Full title: The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

Authors: Blank, Christian U

Year: 2014

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000054

Paper Anti-CTLA-4 therapy may have mechanisms similar to those occurring in inherited human CTLA4 haploinsufficiency.

Bakacs, Tibor, Mehrishi, Jitendra N · 2015 · Immunobiology · DOI

Full title: Anti-CTLA-4 therapy may have mechanisms similar to those occurring in inherited human CTLA4 haploinsufficiency.

Authors: Bakacs, Tibor, Mehrishi, Jitendra N

Year: 2015

Venue: Immunobiology

DOI: https://doi.org/10.1016/j.imbio.2014.11.019

Paper Immune Checkpoint Inhibitor-Induced Upper Gastrointestinal Tract Inflammation Shows Morphologic Similarities to, but Is Immunologically Distinct From, Helicobacter pylori Gastritis and Celiac Disease.

Irshaid, Lina, Robert, Marie E, Zhang, Xuchen · 2021 · Archives of pathology & laboratory medicine · DOI

Full title: Immune Checkpoint Inhibitor-Induced Upper Gastrointestinal Tract Inflammation Shows Morphologic Similarities to, but Is Immunologically Distinct From, Helicobacter pylori Gastritis and Celiac Disease.

Authors: Irshaid, Lina, Robert, Marie E, Zhang, Xuchen

Year: 2021

Venue: Archives of pathology & laboratory medicine

DOI: https://doi.org/10.5858/arpa.2019-0700-OA

Paper A phase II clinical trial of ipilimumab/nivolumab combination immunotherapy in patients with rare upper gastrointestinal, neuroendocrine, and gynecological malignancies.

Klein, Oliver, Kee, Damien, Markman, Ben, Lee, Rachael Chang, Michael, Michael, Mileshkin, Linda, Scott, Clare L., Linklater, Richelle, Menon, Sid, Tebbutt, Niall C., Palmer, Jodie, Behren, Andreas, Cebon, Jonathan · 2019 · Journal of Clinical Oncology · DOI

Full title: A phase II clinical trial of ipilimumab/nivolumab combination immunotherapy in patients with rare upper gastrointestinal, neuroendocrine, and gynecological malignancies.

Authors: Klein, Oliver, Kee, Damien, Markman, Ben, Lee, Rachael Chang, Michael, Michael, Mileshkin, Linda, Scott, Clare L., Linklater, Richelle, Menon, Sid, Tebbutt, Niall C., Palmer, Jodie, Behren, Andreas, Cebon, Jonathan

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.2570

Paper Rationalizing rules for immunotherapy combination trials: About time for precision immunotherapy.

Desai, Aakash, Subbiah, Vivek · 2023 · Cancer · DOI

Full title: Rationalizing rules for immunotherapy combination trials: About time for precision immunotherapy.

Authors: Desai, Aakash, Subbiah, Vivek

Year: 2023

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.34514

Paper Chimeric antigen receptor T cell therapy and other therapeutics for malignancies: Combination and opportunity.

Wang, Luyao, Yao, Ruixue, Zhang, Lifa, Fan, Chuanbo, Ma, Leina, Liu, Jia · 2019 · International immunopharmacology · DOI

Full title: Chimeric antigen receptor T cell therapy and other therapeutics for malignancies: Combination and opportunity.

Authors: Wang, Luyao, Yao, Ruixue, Zhang, Lifa, Fan, Chuanbo, Ma, Leina, Liu, Jia

Year: 2019

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2019.01.010

Paper Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles

Feng, Bing, Niu, Zifei, Hou, Bo, Zhou, Lei, Li, Yaping, Yu, Haijun · 2019 · Advanced Functional Materials · DOI

Full title: Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles

Authors: Feng, Bing, Niu, Zifei, Hou, Bo, Zhou, Lei, Li, Yaping, Yu, Haijun

Year: 2019

Venue: Advanced Functional Materials

DOI: https://doi.org/10.1002/adfm.201906605

Paper Efficacy and safety of anti-programmed cell death protein 1 antibody combination therapy in patients with advanced experienced epidermal growth factor receptor-tyrosine kinase inhibitor-resistant lung adenocarcinoma: a retrospective cohort study

Wan, Chang, Zhang, Yiruo, Liu, Pingping, Mei, Xinkuan, Cheng, Gang, Pang, Jingdan, Chen, Sheng, Xu, Jianping, Malhotra, Jyoti, Qian, Hesheng, Du, Yingying · 2023 · Journal of Thoracic Disease · DOI

Full title: Efficacy and safety of anti-programmed cell death protein 1 antibody combination therapy in patients with advanced experienced epidermal growth factor receptor-tyrosine kinase inhibitor-resistant lung adenocarcinoma: a retrospective cohort study

Authors: Wan, Chang, Zhang, Yiruo, Liu, Pingping, Mei, Xinkuan, Cheng, Gang, Pang, Jingdan, Chen, Sheng, Xu, Jianping, Malhotra, Jyoti, Qian, Hesheng, Du, Yingying

Year: 2023

Venue: Journal of Thoracic Disease

DOI: https://doi.org/10.21037/jtd-23-1399

Paper Association of baseline neutrophil-to-eosinophil ratio (NER) and neutrophil-to-lymphocyte ratio (NLR) with response to combination immunotherapy (IO) with ipilimumab plus nivolumab (ipi/nivo) in patients with metastatic renal cell carcinoma (mRCC).

M. Tucker, L. Brown, Chester Kao, Nathan Hirshman, E. Kinsey, Yu-Wei Chen, K. Ancell, K. Beckermann, N. Davis, Renee McAlister, K. Schaffer, A. Armstrong, M. Harrison, D. George, W. Rathmell, B. Rini, Tian Zhang · 2021 · Journal of Clinical Oncology · DOI

Full title: Association of baseline neutrophil-to-eosinophil ratio (NER) and neutrophil-to-lymphocyte ratio (NLR) with response to combination immunotherapy (IO) with ipilimumab plus nivolumab (ipi/nivo) in patients with metastatic renal cell carcinoma (mRCC).

Authors: M. Tucker, L. Brown, Chester Kao, Nathan Hirshman, E. Kinsey, Yu-Wei Chen, K. Ancell, K. Beckermann, N. Davis, Renee McAlister, K. Schaffer, A. Armstrong, M. Harrison, D. George, W. Rathmell, B. Rini, Tian Zhang

Year: 2021

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2021.39.15_suppl.4563

Paper SY4-1 Combination immunotherapy using anti-PD-1/PD-L1 plus anti-CTLA-4 antibodies

M. Reck · 2021 · Annals of Oncology · DOI

Full title: SY4-1 Combination immunotherapy using anti-PD-1/PD-L1 plus anti-CTLA-4 antibodies

Authors: M. Reck

Year: 2021

Venue: Annals of Oncology

DOI: https://doi.org/10.1016/j.annonc.2021.05.423

Paper Effectiveness of PD-1/PD-L1 inhibitors in the treatment of lung cancer: Brightness and challenge.

Yang, Ying, Yu, Yongfeng, Lu, Shun · 2020 · Science China. Life sciences · DOI

Full title: Effectiveness of PD-1/PD-L1 inhibitors in the treatment of lung cancer: Brightness and challenge.

Authors: Yang, Ying, Yu, Yongfeng, Lu, Shun

Year: 2020

Venue: Science China. Life sciences

DOI: https://doi.org/10.1007/s11427-019-1622-5

Paper Effectiveness of fourth-line dual immunotherapy in hepatocellular carcinoma with simultaneous steroid administration for immune-related hepatitis.

Lowes, Kristina, Reinecke, Johanna, Brunner, Marius, Scholz, Matthias, Kitz, Julia, Michels, Beate, Mekolli, Ardian, Gaedcke, Jochen, Seif Amir Hosseini, Ali, Ströbel, Philipp, Ghadimi, Michael, Ellenrieder, Volker, Koenig, Alexander, Koenig, Ute · 2022 · Therapeutic advances in gastroenterology · DOI

Full title: Effectiveness of fourth-line dual immunotherapy in hepatocellular carcinoma with simultaneous steroid administration for immune-related hepatitis.

Authors: Lowes, Kristina, Reinecke, Johanna, Brunner, Marius, Scholz, Matthias, Kitz, Julia, Michels, Beate, Mekolli, Ardian, Gaedcke, Jochen, Seif Amir Hosseini, Ali, Ströbel, Philipp, Ghadimi, Michael, Ellenrieder, Volker, Koenig, Alexander, Koenig, Ute

Year: 2022

Venue: Therapeutic advances in gastroenterology

DOI: https://doi.org/10.1177/17562848211051026

Paper DGKA Mediates Resistance to PD-1 Blockade

Fu, Lingyi, Li, Sen, Xiao, Weiwei, Yu, Kuai, Li, Shuo, Yuan, Sujing, Shen, Jianfei, Dong, Xingjun, Fang, Ziqian, Zhang, Jianeng, Chen, Siyu, Li, Wende, You, Hua, Xia, Xiaojun, Kang, Tiebang, Tan, Jing, Chen, Gong, Yang, Ankui, Gao, Yuanhong, Zhou, Penghui · 2021 · Cancer Immunology Research · DOI

Full title: DGKA Mediates Resistance to PD-1 Blockade

Authors: Fu, Lingyi, Li, Sen, Xiao, Weiwei, Yu, Kuai, Li, Shuo, Yuan, Sujing, Shen, Jianfei, Dong, Xingjun, Fang, Ziqian, Zhang, Jianeng, Chen, Siyu, Li, Wende, You, Hua, Xia, Xiaojun, Kang, Tiebang, Tan, Jing, Chen, Gong, Yang, Ankui, Gao, Yuanhong, Zhou, Penghui

Year: 2021

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-20-0216

Paper Immunotherapy Combinations With Checkpoint Inhibitors in Metastatic Melanoma: Current Approaches and Future Directions.

Atkins, Michael · 2015 · Seminars in oncology · DOI

Full title: Immunotherapy Combinations With Checkpoint Inhibitors in Metastatic Melanoma: Current Approaches and Future Directions.

Authors: Atkins, Michael

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.10.002

Paper Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma.

De Martino, Mara, Daviaud, Camille, Lira, María Cecilia, Hernandez-Zirofsky, Kayla, Vanpouille-Box, Claire · 2025 · Cancer letters · DOI

Full title: Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma.

Authors: De Martino, Mara, Daviaud, Camille, Lira, María Cecilia, Hernandez-Zirofsky, Kayla, Vanpouille-Box, Claire

Year: 2025

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2025.217856

Paper Outcomes of patients with advanced solid tumors who discontinued immune-checkpoint inhibitors: a systematic review and meta-analysis.

Pala, Laura, Pagan, Eleonora, Sala, Isabella, Oriecuia, Chiara, Oliari, Matteo, De Pas, Tommaso, Specchia, Claudia, Cocorocchio, Emilia, Zattarin, Emma, Rossi, Giovanna, Catania, Chiara, Ceresoli, Giovanni Luca, Laszlo, Daniele, Canzian, Jacopo, Valenzi, Elena, Viale, Giuseppe, Gelber, Richard D, Mantovani, Alberto, Bagnardi, Vincenzo, Conforti, Fabio · 2024 · EClinicalMedicine · DOI

Full title: Outcomes of patients with advanced solid tumors who discontinued immune-checkpoint inhibitors: a systematic review and meta-analysis.

Authors: Pala, Laura, Pagan, Eleonora, Sala, Isabella, Oriecuia, Chiara, Oliari, Matteo, De Pas, Tommaso, Specchia, Claudia, Cocorocchio, Emilia, Zattarin, Emma, Rossi, Giovanna, Catania, Chiara, Ceresoli, Giovanni Luca, Laszlo, Daniele, Canzian, Jacopo, Valenzi, Elena, Viale, Giuseppe, Gelber, Richard D, Mantovani, Alberto, Bagnardi, Vincenzo, Conforti, Fabio

Year: 2024

Venue: EClinicalMedicine

DOI: https://doi.org/10.1016/j.eclinm.2024.102681

Paper Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Larkin, James, Chiarion‐Sileni, Vanna, González, René, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Schadendorf, Dirk, Dummer, Reinhard, Smylie, Michael, Rutkowski, Piotr, Ferrucci, Pier Francesco, Hill, Andrew, Wagstaff, John, Carlino, Matteo S., Haanen, John B.A.G., Maio, Michele, Márquez‐Rodas, Iván, McArthur, Grant A., Ascierto, Paolo A., Long, Georgina V., Callahan, Margaret K., Postow, Michael A., Grossmann, Kenneth F., Sznol, Mario, Dréno, Brigitte, Bastholt, Lars, Yang, Arvin, Rollin, Linda M., Horak, Christine E., Hodi, F. Stephen, Wolchok, Jedd D. · 2015 · New England Journal of Medicine · DOI

Full title: Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Authors: Larkin, James, Chiarion‐Sileni, Vanna, González, René, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Schadendorf, Dirk, Dummer, Reinhard, Smylie, Michael, Rutkowski, Piotr, Ferrucci, Pier Francesco, Hill, Andrew, Wagstaff, John, Carlino, Matteo S., Haanen, John B.A.G., Maio, Michele, Márquez‐Rodas, Iván, McArthur, Grant A., Ascierto, Paolo A., Long, Georgina V., Callahan, Margaret K., Postow, Michael A., Grossmann, Kenneth F., Sznol, Mario, Dréno, Brigitte, Bastholt, Lars, Yang, Arvin, Rollin, Linda M., Horak, Christine E., Hodi, F. Stephen, Wolchok, Jedd D.

Year: 2015

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1504030

Paper Seasonal patterns of toxicity in melanoma patients treated with combination anti-PD-1 and anti-CTLA-4 immunotherapy.

Rogiers, Aljosja, Dimitriou, Florentia, Lobon, Irene, Harvey, Catriona, Vergara, Ismael A, Pires da Silva, Ines, Lo, Serigne N, Scolyer, Richard A, Carlino, Matteo S, Menzies, Alexander M, Long, Georgina V · 2024 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Seasonal patterns of toxicity in melanoma patients treated with combination anti-PD-1 and anti-CTLA-4 immunotherapy.

Authors: Rogiers, Aljosja, Dimitriou, Florentia, Lobon, Irene, Harvey, Catriona, Vergara, Ismael A, Pires da Silva, Ines, Lo, Serigne N, Scolyer, Richard A, Carlino, Matteo S, Menzies, Alexander M, Long, Georgina V

Year: 2024

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2023.113506

Paper Complete Remission of Metastatic Melanoma of the Scalp Following Treatment With Nivolumab Plus Relatlimab.

McMinn, Mary E, Brister, Kelly A, Orr, W Shannon, Sheehan, Natale T, Christopher, Wade O · 2024 · The American surgeon · DOI

Full title: Complete Remission of Metastatic Melanoma of the Scalp Following Treatment With Nivolumab Plus Relatlimab.

Authors: McMinn, Mary E, Brister, Kelly A, Orr, W Shannon, Sheehan, Natale T, Christopher, Wade O

Year: 2024

Venue: The American surgeon

DOI: https://doi.org/10.1177/00031348241241642

Paper Enhancement of lymphokine-activated killer cell induction using anti-CD25 and anti-CTLA-4 monoclonal antibodies.

Okita, Riki, Yamaguchi, Yoshiyuki, Emi, Akiko, Matsuura, Kazuo, Toge, Tetsuya · 2007 · Oncology reports

Full title: Enhancement of lymphokine-activated killer cell induction using anti-CD25 and anti-CTLA-4 monoclonal antibodies.

Authors: Okita, Riki, Yamaguchi, Yoshiyuki, Emi, Akiko, Matsuura, Kazuo, Toge, Tetsuya

Year: 2007

Venue: Oncology reports

Paper Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer.

Pack, Christopher D, Bommireddy, Ramireddy, Munoz, Luis E, Patel, Jaina M, Bozeman, Erica N, Dey, Paulami, Radhakrishnan, Vijayaraghavan, Vartabedian, Vincent F, Venkat, Kalpana, Ramachandiran, Sampath, Reddy, Shaker J C, Selvaraj, Periasamy · 2020 · Human vaccines & immunotherapeutics · DOI

Full title: Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer.

Authors: Pack, Christopher D, Bommireddy, Ramireddy, Munoz, Luis E, Patel, Jaina M, Bozeman, Erica N, Dey, Paulami, Radhakrishnan, Vijayaraghavan, Vartabedian, Vincent F, Venkat, Kalpana, Ramachandiran, Sampath, Reddy, Shaker J C, Selvaraj, Periasamy

Year: 2020

Venue: Human vaccines & immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2020.1754691

Paper Integrin signaling gene alterations and outcomes of cancer patients receiving immune checkpoint inhibitors.

Vlachostergios, Panagiotis J · 2021 · American journal of translational research

Full title: Integrin signaling gene alterations and outcomes of cancer patients receiving immune checkpoint inhibitors.

Authors: Vlachostergios, Panagiotis J

Year: 2021

Venue: American journal of translational research

Paper Safety evaluation of durvalumab for the treatment of non-small-cell lung cancer.

Shibata, Yuji, Murakami, Shuji · 2020 · Expert opinion on drug safety · DOI

Full title: Safety evaluation of durvalumab for the treatment of non-small-cell lung cancer.

Authors: Shibata, Yuji, Murakami, Shuji

Year: 2020

Venue: Expert opinion on drug safety

DOI: https://doi.org/10.1080/14740338.2020.1764936

Paper A phase I trial of combination immunotherapy with CTLA-4 blockade and GM-CSF in hormone-refractory prostate cancer

Fong, Lawrence, Kavanagh, Brian D., Rini, Brian I., Shaw, Vanessa, Weinberg, Vivian, Small, Eric J. · 2006 · Journal of Clinical Oncology · DOI

Full title: A phase I trial of combination immunotherapy with CTLA-4 blockade and GM-CSF in hormone-refractory prostate cancer

Authors: Fong, Lawrence, Kavanagh, Brian D., Rini, Brian I., Shaw, Vanessa, Weinberg, Vivian, Small, Eric J.

Year: 2006

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2006.24.18_suppl.2508

Paper Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma

Foley, Kendra C., Nishimura, Michael I., Moore, Tamson V. · 2018 · Melanoma Research · DOI

Full title: Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma

Authors: Foley, Kendra C., Nishimura, Michael I., Moore, Tamson V.

Year: 2018

Venue: Melanoma Research

DOI: https://doi.org/10.1097/cmr.0000000000000436

Paper Immune checkpoint inhibitors in non-small cell lung cancer: from current perspectives to future treatments-a systematic review.

Olivares-Hernández, Alejandro, González Del Portillo, Elísabet, Tamayo-Velasco, Álvaro, Figuero-Pérez, Luis, Zhilina-Zhilina, Svetlana, Fonseca-Sánchez, Emilio, Miramontes-González, José Pablo · 2023 · Annals of translational medicine · DOI

Full title: Immune checkpoint inhibitors in non-small cell lung cancer: from current perspectives to future treatments-a systematic review.

Authors: Olivares-Hernández, Alejandro, González Del Portillo, Elísabet, Tamayo-Velasco, Álvaro, Figuero-Pérez, Luis, Zhilina-Zhilina, Svetlana, Fonseca-Sánchez, Emilio, Miramontes-González, José Pablo

Year: 2023

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm-22-4218

Paper [18F]FDG-PET/CT Imaging for Response Characterisation of Experimental Melanomas to Anti-PD-L1/Anti-CTLA-4 Immunotherapy.

Antons, Melissa J, Kloiber-Langhorst, Sandra, Hirner-Eppeneder, Heidrun, Schaefer, Rebecca, Stueckl, Jennifer, Palumbo, Giovanna, Oos, Rosel, Herr, Felix L, Lindner, Simon, Ziegler, Sibylle, Brendel, Matthias, Ricke, Jens, Werner, Rudolf A, Heimer, Maurice M, Cyran, Clemens C · 2025 · Molecular imaging and biology · DOI

Full title: [18F]FDG-PET/CT Imaging for Response Characterisation of Experimental Melanomas to Anti-PD-L1/Anti-CTLA-4 Immunotherapy.

Authors: Antons, Melissa J, Kloiber-Langhorst, Sandra, Hirner-Eppeneder, Heidrun, Schaefer, Rebecca, Stueckl, Jennifer, Palumbo, Giovanna, Oos, Rosel, Herr, Felix L, Lindner, Simon, Ziegler, Sibylle, Brendel, Matthias, Ricke, Jens, Werner, Rudolf A, Heimer, Maurice M, Cyran, Clemens C

Year: 2025

Venue: Molecular imaging and biology

DOI: https://doi.org/10.1007/s11307-025-02056-7

Paper Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced malignant tumors

Zhang, Li, Zhao, Hongyun, Huang, Yan, Fang, Wenfeng, Ma, Yuxiang, Zhang, Yang, Wei, Xiaoli, Yang, Yanhua, Yang, Wei, Liu, Furong, Lin, Zuan, Li, Jianing, Liu, Qianwen, Zou, Benyan, Liao, Kunlun, Liu, Qun · 2022 · Cancer Research · DOI

Full title: Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced malignant tumors

Authors: Zhang, Li, Zhao, Hongyun, Huang, Yan, Fang, Wenfeng, Ma, Yuxiang, Zhang, Yang, Wei, Xiaoli, Yang, Yanhua, Yang, Wei, Liu, Furong, Lin, Zuan, Li, Jianing, Liu, Qianwen, Zou, Benyan, Liao, Kunlun, Liu, Qun

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2022-ct520

Paper Immune checkpoint blockade immunotherapy to activate anti‐tumour T ‐cell immunity

Ramsay, Alan G. · 2013 · British Journal of Haematology · DOI

Full title: Immune checkpoint blockade immunotherapy to activate anti‐tumour T ‐cell immunity

Authors: Ramsay, Alan G.

Year: 2013

Venue: British Journal of Haematology

DOI: https://doi.org/10.1111/bjh.12380

Paper Immunotherapy combinations and chemotherapy sparing schemes in first line non-small cell lung cancer.

Sereno, María, Higuera, Oliver, Cruz Castellanos, Patricia, Falagan, Sandra, Mielgo-Rubio, Xabier, Trujillo-Reyes, Juan Carlos, Couñago, Felipe · 2021 · World journal of clinical oncology · DOI

Full title: Immunotherapy combinations and chemotherapy sparing schemes in first line non-small cell lung cancer.

Authors: Sereno, María, Higuera, Oliver, Cruz Castellanos, Patricia, Falagan, Sandra, Mielgo-Rubio, Xabier, Trujillo-Reyes, Juan Carlos, Couñago, Felipe

Year: 2021

Venue: World journal of clinical oncology

DOI: https://doi.org/10.5306/wjco.v12.i12.1182

Paper CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination.

Ahrends, Tomasz, Bąbała, Nikolina, Xiao, Yanling, Yagita, Hideo, van Eenennaam, Hans, Borst, Jannie · 2016 · Cancer research · DOI

Full title: CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination.

Authors: Ahrends, Tomasz, Bąbała, Nikolina, Xiao, Yanling, Yagita, Hideo, van Eenennaam, Hans, Borst, Jannie

Year: 2016

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-15-3130

Paper OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models.

Estrada, Juan, Zhan, Jinghui, Mitchell, Petia, Werner, Jonathan, Beltran, Pedro J, DeVoss, Jason, Qing, Jing, Cooke, Keegan S · 2023 · Journal for immunotherapy of cancer · DOI

Full title: OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models.

Authors: Estrada, Juan, Zhan, Jinghui, Mitchell, Petia, Werner, Jonathan, Beltran, Pedro J, DeVoss, Jason, Qing, Jing, Cooke, Keegan S

Year: 2023

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2022-006374

Paper A phase II study of dual immune checkpoint blockade (ICB) plus androgen receptor (AR) blockade to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC).

Page, David B., Kim, Isaac K, Chun, Brie, Redmond, William L., Martel, Maritza, Mori, Motomi, Wadell, Dottie, Moxon, Nicole, Mellinger, Staci, Urba, Walter J., Gucalp, Ayca, Traina, Tiffany A. · 2019 · Journal of Clinical Oncology · DOI

Full title: A phase II study of dual immune checkpoint blockade (ICB) plus androgen receptor (AR) blockade to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC).

Authors: Page, David B., Kim, Isaac K, Chun, Brie, Redmond, William L., Martel, Maritza, Mori, Motomi, Wadell, Dottie, Moxon, Nicole, Mellinger, Staci, Urba, Walter J., Gucalp, Ayca, Traina, Tiffany A.

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.tps1106

Paper A combined radio-immunotherapy regimen eradicates late-stage tumors in mice.

Rakhmilevich, Alexander L, Tsarovsky, Noah W, Felder, Mildred, Zaborek, Jen, Moram, Sritha, Erbe, Amy K, Pieper, Alexander A, Spiegelman, Dan V, Cheng, Emily M, Witt, Cole M, Overwijk, Willem W, Morris, Zachary S, Sondel, Paul M · 2024 · Frontiers in immunology · DOI

Full title: A combined radio-immunotherapy regimen eradicates late-stage tumors in mice.

Authors: Rakhmilevich, Alexander L, Tsarovsky, Noah W, Felder, Mildred, Zaborek, Jen, Moram, Sritha, Erbe, Amy K, Pieper, Alexander A, Spiegelman, Dan V, Cheng, Emily M, Witt, Cole M, Overwijk, Willem W, Morris, Zachary S, Sondel, Paul M

Year: 2024

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2024.1419773

Paper Clinical Benefits of Combination Immunotherapy Over Standard Immunotherapy Monotherapy in Previously Treated Advanced Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Chen, Yong, Chen, Zixuan, Guo, Hong, Zhou, Heng, Deng, Yizhou, Wang, Rui, Han, Fang, Mao, Haiyan, Zhang, Zhengrong, Wu, Yunjiang, Li, Ying · 2025 · Cancer medicine · DOI

Full title: Clinical Benefits of Combination Immunotherapy Over Standard Immunotherapy Monotherapy in Previously Treated Advanced Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Authors: Chen, Yong, Chen, Zixuan, Guo, Hong, Zhou, Heng, Deng, Yizhou, Wang, Rui, Han, Fang, Mao, Haiyan, Zhang, Zhengrong, Wu, Yunjiang, Li, Ying

Year: 2025

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.71329

Paper Clinical Development of PD-1/PD-L1 Inhibitors in Breast Cancer: Still a Long Way to Go.

Barroso-Sousa, Romualdo, Tolaney, Sara M · 2020 · Current treatment options in oncology · DOI

Full title: Clinical Development of PD-1/PD-L1 Inhibitors in Breast Cancer: Still a Long Way to Go.

Authors: Barroso-Sousa, Romualdo, Tolaney, Sara M

Year: 2020

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-020-00756-6

Paper Immunotherapy of patients with metastatic melanoma.

Yu, Zhe, Si, Lu · 2017 · Chinese clinical oncology · DOI

Full title: Immunotherapy of patients with metastatic melanoma.

Authors: Yu, Zhe, Si, Lu

Year: 2017

Venue: Chinese clinical oncology

DOI: https://doi.org/10.21037/cco.2017.04.01

Paper [Not Available].

Mignard, Xavier, Chaabane, Nouha, Fallet, Vincent, Wislez, Marie · 2018 · Bulletin du cancer · DOI

Full title: [Not Available].

Authors: Mignard, Xavier, Chaabane, Nouha, Fallet, Vincent, Wislez, Marie

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/S0007-4551(18)30386-2

Paper Immune Checkpoint inhibitors: An introduction to the next‐generation cancer immunotherapy

Lee, Lucy, Gupta, Manish, Sahasranaman, Srikumar · 2015 · The Journal of Clinical Pharmacology · DOI

Full title: Immune Checkpoint inhibitors: An introduction to the next‐generation cancer immunotherapy

Authors: Lee, Lucy, Gupta, Manish, Sahasranaman, Srikumar

Year: 2015

Venue: The Journal of Clinical Pharmacology

DOI: https://doi.org/10.1002/jcph.591

Paper Acute Interstitial Nephritis and Renal Tubular Acidosis Associated with Bispecific Anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT)/Anti-Programmed Cell Death Protein 1 (PD-1) Therapy

Kabir, M. D. Golam, Bonilla, Marco · 2025 · Journal of the American Society of Nephrology · DOI

Full title: Acute Interstitial Nephritis and Renal Tubular Acidosis Associated with Bispecific Anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT)/Anti-Programmed Cell Death Protein 1 (PD-1) Therapy

Authors: Kabir, M. D. Golam, Bonilla, Marco

Year: 2025

Venue: Journal of the American Society of Nephrology

DOI: https://doi.org/10.1681/asn.2025dj14h9z1

Paper Next-generation immunotherapy for solid tumors: combination immunotherapy with crosstalk blockade of TGFβ and PD-1/PD-L1

Quach, Hue Tu, Hou, Zhaohua, Bellis, Rebecca Y., Saini, Jasmeen, Amador-Molina, Alfredo, Adusumilli, Prasad S., Xiong, Yuquan · 2022 · Expert Opinion on Investigational Drugs · DOI

Full title: Next-generation immunotherapy for solid tumors: combination immunotherapy with crosstalk blockade of TGFβ and PD-1/PD-L1

Authors: Quach, Hue Tu, Hou, Zhaohua, Bellis, Rebecca Y., Saini, Jasmeen, Amador-Molina, Alfredo, Adusumilli, Prasad S., Xiong, Yuquan

Year: 2022

Venue: Expert Opinion on Investigational Drugs

DOI: https://doi.org/10.1080/13543784.2022.2152323

Paper Advanced fumarate hydratase-deficient renal cell carcinoma responding to combination immune checkpoint inhibitors.

Howells, Erin, Wigston, Lucas, Mackie, Gavin, Tran, Ben, Nott, Louise · 2023 · The Canadian journal of urology

Full title: Advanced fumarate hydratase-deficient renal cell carcinoma responding to combination immune checkpoint inhibitors.

Authors: Howells, Erin, Wigston, Lucas, Mackie, Gavin, Tran, Ben, Nott, Louise

Year: 2023

Venue: The Canadian journal of urology

Paper In Situ Cocktail Nanovaccine for Cancer Immunotherapy.

Liu, Mohan, Xie, Daoyuan, Hu, Die, Zhang, Rui, Wang, Yusi, Tang, Lin, Zhou, Bailing, Zhao, Binyan, Yang, Li · 2023 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: In Situ Cocktail Nanovaccine for Cancer Immunotherapy.

Authors: Liu, Mohan, Xie, Daoyuan, Hu, Die, Zhang, Rui, Wang, Yusi, Tang, Lin, Zhou, Bailing, Zhao, Binyan, Yang, Li

Year: 2023

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202207697

Paper First-Line Immune Checkpoint Inhibition for Advanced Non-Small-Cell Lung Cancer: State of the Art and Future Directions.

Ackermann, Christoph Jakob, Adderley, Helen, Ortega-Franco, Ana, Khan, Adeel, Reck, Martin, Califano, Raffaele · 2020 · Drugs · DOI

Full title: First-Line Immune Checkpoint Inhibition for Advanced Non-Small-Cell Lung Cancer: State of the Art and Future Directions.

Authors: Ackermann, Christoph Jakob, Adderley, Helen, Ortega-Franco, Ana, Khan, Adeel, Reck, Martin, Califano, Raffaele

Year: 2020

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-020-01409-6

Paper Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

Tawbi, Hussein A., Forsyth, Peter, Algazi, Alain P., Hamid, Omid, Hodi, F. Stephen, Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl D., Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena, Tarhini, Ahmad A., Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim · 2018 · New England Journal of Medicine · DOI

Full title: Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

Authors: Tawbi, Hussein A., Forsyth, Peter, Algazi, Alain P., Hamid, Omid, Hodi, F. Stephen, Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl D., Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena, Tarhini, Ahmad A., Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1805453

Paper SWOG/NCI Phase II Dual Anti-CTLA-4/PD-1 Blockade in Rare Tumors: Nonepithelial Ovarian Cancer.

Chae, Young Kwang, Othus, Megan, Patel, Sandip Pravin, Wilkinson, Kelly J, Whitman-Purves, Emily M, Lea, Jayanthi, Schallenkamp, John M, Adra, Nabil, Appleman, Leonard J, Alden, Mitchell, Thomes Pepin, Jessica, Ellerton, John A, Poklepovic, Andrew, Walter, Adam, Rampurwala, Murtuza M, Robinson, William R, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine M, Lopez, Gabby, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle · 2024 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: SWOG/NCI Phase II Dual Anti-CTLA-4/PD-1 Blockade in Rare Tumors: Nonepithelial Ovarian Cancer.

Authors: Chae, Young Kwang, Othus, Megan, Patel, Sandip Pravin, Wilkinson, Kelly J, Whitman-Purves, Emily M, Lea, Jayanthi, Schallenkamp, John M, Adra, Nabil, Appleman, Leonard J, Alden, Mitchell, Thomes Pepin, Jessica, Ellerton, John A, Poklepovic, Andrew, Walter, Adam, Rampurwala, Murtuza M, Robinson, William R, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine M, Lopez, Gabby, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle

Year: 2024

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-24-0606

Paper A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Preclinical Models.

Willingham, Stephen B, Ho, Po Y, Hotson, Andrew, Hill, Craig, Piccione, Emily C, Hsieh, Jessica, Liu, Liang, Buggy, Joseph J, McCaffery, Ian, Miller, Richard A · 2018 · Cancer immunology research · DOI

Full title: A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Preclinical Models.

Authors: Willingham, Stephen B, Ho, Po Y, Hotson, Andrew, Hill, Craig, Piccione, Emily C, Hsieh, Jessica, Liu, Liang, Buggy, Joseph J, McCaffery, Ian, Miller, Richard A

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0056

Paper Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical models

Ghosh, Arnab, Michel, Judith, Dong, Lauren, Suek, Nathan, Zhong, Hong, Budhu, Sadna, Henau, Olivier De, Wolchok, Jedd D., Merghoub, Taha · 2019 · Cancer Research · DOI

Full title: Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical models

Authors: Ghosh, Arnab, Michel, Judith, Dong, Lauren, Suek, Nathan, Zhong, Hong, Budhu, Sadna, Henau, Olivier De, Wolchok, Jedd D., Merghoub, Taha

Year: 2019

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2019-4843

Paper Immune checkpoint combinations from mouse to man.

Ai, Midan, Curran, Michael A · 2015 · Cancer immunology, immunotherapy : CII · DOI

Full title: Immune checkpoint combinations from mouse to man.

Authors: Ai, Midan, Curran, Michael A

Year: 2015

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-014-1650-8

Paper Combining immunotherapies for the treatment of prostate cancer.

Redman, Jason M, Gulley, James L, Madan, Ravi A · 2017 · Urologic oncology · DOI

Full title: Combining immunotherapies for the treatment of prostate cancer.

Authors: Redman, Jason M, Gulley, James L, Madan, Ravi A

Year: 2017

Venue: Urologic oncology

DOI: https://doi.org/10.1016/j.urolonc.2017.09.024

Paper Immune checkpoint inhibitors in non-conventional histologies of renal-cell carcinoma

Bersanelli, Melissa, Rebuzzi, Sara Elena, Roviello, Giandomenico, Catalano, Martina, Brunelli, Matteo, Rizzo, Mimma · 2023 · Human Vaccines & Immunotherapeutics · DOI

Full title: Immune checkpoint inhibitors in non-conventional histologies of renal-cell carcinoma

Authors: Bersanelli, Melissa, Rebuzzi, Sara Elena, Roviello, Giandomenico, Catalano, Martina, Brunelli, Matteo, Rizzo, Mimma

Year: 2023

Venue: Human Vaccines & Immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2023.2171672

Paper A Phase I/II adaptive design to determine the optimal treatment regimen from a set of combination immunotherapies in high-risk melanoma.

N. Wages, C. Slingluff, G. Petroni · 2015 · Contemporary Clinical Trials · DOI

Full title: A Phase I/II adaptive design to determine the optimal treatment regimen from a set of combination immunotherapies in high-risk melanoma.

Authors: N. Wages, C. Slingluff, G. Petroni

Year: 2015

Venue: Contemporary Clinical Trials

DOI: https://doi.org/10.1016/j.cct.2015.01.016

Paper Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1.

Mok, Stephen, Liu, Huey, Ağaç Çobanoğlu, Didem, Anang, Nana-Ama A S, Mancuso, James J, Wherry, E John, Allison, James P · 2025 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1.

Authors: Mok, Stephen, Liu, Huey, Ağaç Çobanoğlu, Didem, Anang, Nana-Ama A S, Mancuso, James J, Wherry, E John, Allison, James P

Year: 2025

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2418985122

Paper Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanoma.

Klemen, Nicholas D, Wang, Melinda, Rubinstein, Jill C, Olino, Kelly, Clune, James, Ariyan, Stephan, Cha, Charles, Weiss, Sarah A, Kluger, Harriet M, Sznol, Mario · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanoma.

Authors: Klemen, Nicholas D, Wang, Melinda, Rubinstein, Jill C, Olino, Kelly, Clune, James, Ariyan, Stephan, Cha, Charles, Weiss, Sarah A, Kluger, Harriet M, Sznol, Mario

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2019-000341

Paper Catalytic Intermolecular Asymmetric [2π + 2σ] Cycloadditions of Bicyclo[1.1.0]butanes: Practical Synthesis of Enantioenriched Highly Substituted Bicyclo[2.1.1]hexanes.

Yingjun Li, Zhicai Wu, Qiangshuai Gu, Tingting Fan, Ming-Hao Duan, Lihong Wu, Yu-Tao Wang, Ji-Peng Wu, Fang-Lei Fu, Fan Sang, Ai-Ting Peng, Yuyang Jiang, Xin-Yuan Liu, Jin-Shun Lin · 2024 · Journal of the American Chemical Society · DOI

Full title: Catalytic Intermolecular Asymmetric [2π + 2σ] Cycloadditions of Bicyclo[1.1.0]butanes: Practical Synthesis of Enantioenriched Highly Substituted Bicyclo[2.1.1]hexanes.

Authors: Yingjun Li, Zhicai Wu, Qiangshuai Gu, Tingting Fan, Ming-Hao Duan, Lihong Wu, Yu-Tao Wang, Ji-Peng Wu, Fang-Lei Fu, Fan Sang, Ai-Ting Peng, Yuyang Jiang, Xin-Yuan Liu, Jin-Shun Lin

Year: 2024

Venue: Journal of the American Chemical Society

DOI: https://doi.org/10.1021/jacs.4c10968

Paper A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking dual immune checkpoints.

Du, Yanlin, Zhang, Da, Wang, Yiru, Wu, Ming, Zhang, Cuilin, Zheng, Youshi, Zheng, Aixian, Liu, Xiaolong · 2021 · Biomaterials science · DOI

Full title: A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking dual immune checkpoints.

Authors: Du, Yanlin, Zhang, Da, Wang, Yiru, Wu, Ming, Zhang, Cuilin, Zheng, Youshi, Zheng, Aixian, Liu, Xiaolong

Year: 2021

Venue: Biomaterials science

DOI: https://doi.org/10.1039/d0bm02210a

Paper Development of Poliosis Following Checkpoint Inhibitor Treatment for Cutaneous Melanoma.

Ediriwickrema, Lilangi S, Liu, Catherine Y, Kikkawa, Don O, Korn, Bobby S · 2019 · Ophthalmic plastic and reconstructive surgery · DOI

Full title: Development of Poliosis Following Checkpoint Inhibitor Treatment for Cutaneous Melanoma.

Authors: Ediriwickrema, Lilangi S, Liu, Catherine Y, Kikkawa, Don O, Korn, Bobby S

Year: 2019

Venue: Ophthalmic plastic and reconstructive surgery

DOI: https://doi.org/10.1097/IOP.0000000000001451

Paper Immunotherapy for extensive-stage small cell lung cancer: current status, challenges and future strategies.

Yan, Jin-Shan, Wang, Yi-Zheng, Zhao, Su-Ya, Na, Fang-Jian, Cui, Zi-Xuan, Cai, Lu-Tong, Li, He-Ming, Zhao, Ming-Fang · 2026 · Cancer letters · DOI

Full title: Immunotherapy for extensive-stage small cell lung cancer: current status, challenges and future strategies.

Authors: Yan, Jin-Shan, Wang, Yi-Zheng, Zhao, Su-Ya, Na, Fang-Jian, Cui, Zi-Xuan, Cai, Lu-Tong, Li, He-Ming, Zhao, Ming-Fang

Year: 2026

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2026.218382

Paper Gastric Carcinoma.

Kim, Young-Sik · 2025 · Current topics in microbiology and immunology · DOI

Full title: Gastric Carcinoma.

Authors: Kim, Young-Sik

Year: 2025

Venue: Current topics in microbiology and immunology

DOI: https://doi.org/10.1007/82_2025_303

Paper Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy.

Xue, Gang, Li, Xin, Kalim, Muhammad, Fang, Jing, Jiang, Zhiwu, Zheng, Ningbo, Wang, Ziyu, Li, Xiaoyin, Abdelrahim, Maen, He, Zhiheng, Nikiforov, Mikhail, Jin, Guangxu, Lu, Yong · 2024 · Cancer cell · DOI

Full title: Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy.

Authors: Xue, Gang, Li, Xin, Kalim, Muhammad, Fang, Jing, Jiang, Zhiwu, Zheng, Ningbo, Wang, Ziyu, Li, Xiaoyin, Abdelrahim, Maen, He, Zhiheng, Nikiforov, Mikhail, Jin, Guangxu, Lu, Yong

Year: 2024

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2024.03.001

Paper Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Gao, Jianjun, Shi, Lewis Zhichang, Zhao, Hao, Chen, Jianfeng, Xiong, Liangwen, He, Qiuming, Chen, Tenghui, Roszik, Jason, Bernatchez, Chantale, Woodman, Scott E, Chen, Pei-Ling, Hwu, Patrick, Allison, James P, Futreal, Andrew, Wargo, Jennifer A, Sharma, Padmanee · 2016 · Cell · DOI

Full title: Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Authors: Gao, Jianjun, Shi, Lewis Zhichang, Zhao, Hao, Chen, Jianfeng, Xiong, Liangwen, He, Qiuming, Chen, Tenghui, Roszik, Jason, Bernatchez, Chantale, Woodman, Scott E, Chen, Pei-Ling, Hwu, Patrick, Allison, James P, Futreal, Andrew, Wargo, Jennifer A, Sharma, Padmanee

Year: 2016

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2016.08.069

Paper [Immunooncology in Urologic Cancers: Current Status].

Grimm, M-O · 2016 · Aktuelle Urologie · DOI

Full title: [Immunooncology in Urologic Cancers: Current Status].

Authors: Grimm, M-O

Year: 2016

Venue: Aktuelle Urologie

DOI: https://doi.org/10.1055/s-0042-113527

Paper Immunomodulatory monoclonal antibodies combined with peptide vaccination provide potent immunotherapy in an aggressive murine neuroblastoma model.

Williams, Emily L, Dunn, Stuart N, James, Sonya, Johnson, Peter W, Cragg, Mark S, Glennie, Martin J, Gray, Juliet C · 2013 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Immunomodulatory monoclonal antibodies combined with peptide vaccination provide potent immunotherapy in an aggressive murine neuroblastoma model.

Authors: Williams, Emily L, Dunn, Stuart N, James, Sonya, Johnson, Peter W, Cragg, Mark S, Glennie, Martin J, Gray, Juliet C

Year: 2013

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3226

Paper Full Spectrum: Efficacy and Toxicity of Immunotherapy in Metastatic Melanoma.

Zibelman, Matthew, Olszanski, Anthony · 2014 · Journal of the National Comprehensive Cancer Network : JNCCN · DOI

Full title: Full Spectrum: Efficacy and Toxicity of Immunotherapy in Metastatic Melanoma.

Authors: Zibelman, Matthew, Olszanski, Anthony

Year: 2014

Venue: Journal of the National Comprehensive Cancer Network : JNCCN

DOI: https://doi.org/10.6004/jnccn.2014.0216

Paper Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic T-lymphocyte antigen-4 blockade in advanced melanoma

Agarwala, Sanjiv S. · 2010 · Melanoma Research · DOI

Full title: Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic T-lymphocyte antigen-4 blockade in advanced melanoma

Authors: Agarwala, Sanjiv S.

Year: 2010

Venue: Melanoma Research

DOI: https://doi.org/10.1097/cmr.0b013e328333bbc8

Paper Removal of Interstitial Hyaluronan Facilitates Subcutaneous Administration and Lymphatic Delivery of Anti-CTLA4 and Improves Antitumor Efficacy.

Gracia, Gracia, Cao, Enyuan, Yuen, Daniel, Ferreira, Vilena D M, Chen, Moore Z, Senyschyn, Danielle, Mintern, Justine D, Johnston, Angus P R, Kang, David W, Feeney, Orlagh M, Porter, Christopher J H · 2026 · Cancer immunology research · DOI

Full title: Removal of Interstitial Hyaluronan Facilitates Subcutaneous Administration and Lymphatic Delivery of Anti-CTLA4 and Improves Antitumor Efficacy.

Authors: Gracia, Gracia, Cao, Enyuan, Yuen, Daniel, Ferreira, Vilena D M, Chen, Moore Z, Senyschyn, Danielle, Mintern, Justine D, Johnston, Angus P R, Kang, David W, Feeney, Orlagh M, Porter, Christopher J H

Year: 2026

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-25-0256

Paper The role of nivolumab in melanoma.

Gomes, Fabio, Serra-Bellver, Patricio, Lorigan, Paul · 2018 · Future oncology (London, England) · DOI

Full title: The role of nivolumab in melanoma.

Authors: Gomes, Fabio, Serra-Bellver, Patricio, Lorigan, Paul

Year: 2018

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2017-0484

Paper Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma

Singh, Kirit, Batich, Kristen A., Wen, Patrick Y., Tan, Aaron C., Bagley, Stephen, Lim, Michael, Platten, Michael, Colman, Howard, Ashley, David M., Chang, Susan M., Rahman, Rifaquat, Galanis, Evanthia, Mansouri, Alireza, Puduvalli, Vinay K., Reardon, David A., Sahebjam, Solmaz, Sampson, John H., Simes, John, Berry, Donald A., Zadeh, Gelareh, Cloughesy, Tim, Mehta, Minesh P., Piantadosi, Steven, Weller, Michael, Heimberger, Amy B., Khasraw, Mustafa · 2021 · Clinical Cancer Research · DOI

Full title: Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma

Authors: Singh, Kirit, Batich, Kristen A., Wen, Patrick Y., Tan, Aaron C., Bagley, Stephen, Lim, Michael, Platten, Michael, Colman, Howard, Ashley, David M., Chang, Susan M., Rahman, Rifaquat, Galanis, Evanthia, Mansouri, Alireza, Puduvalli, Vinay K., Reardon, David A., Sahebjam, Solmaz, Sampson, John H., Simes, John, Berry, Donald A., Zadeh, Gelareh, Cloughesy, Tim, Mehta, Minesh P., Piantadosi, Steven, Weller, Michael, Heimberger, Amy B., Khasraw, Mustafa

Year: 2021

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-21-2681

Paper High CTLA-4 transcriptomic expression correlates with high expression of other checkpoints and with immunotherapy outcome.

Krishnamurthy, Nithya, Nishizaki, Daisuke, Lippman, Scott M, Miyashita, Hirotaka, Nesline, Mary K, Pabla, Sarabjot, Conroy, Jeffrey M, DePietro, Paul, Kato, Shumei, Kurzrock, Razelle · 2024 · Therapeutic advances in medical oncology · DOI

Full title: High CTLA-4 transcriptomic expression correlates with high expression of other checkpoints and with immunotherapy outcome.

Authors: Krishnamurthy, Nithya, Nishizaki, Daisuke, Lippman, Scott M, Miyashita, Hirotaka, Nesline, Mary K, Pabla, Sarabjot, Conroy, Jeffrey M, DePietro, Paul, Kato, Shumei, Kurzrock, Razelle

Year: 2024

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359231220510

Paper Trends in the treatment of advanced hepatocellular carcinoma: immune checkpoint blockade immunotherapy and related combination therapies.

Cheng, Huijuan, Sun, Guodong, Chen, Hao, Li, Yu, Han, Zhijian, Li, Yangbing, Zhang, Peng, Yang, Luxi, Li, Yumin · 2019 · American journal of cancer research

Full title: Trends in the treatment of advanced hepatocellular carcinoma: immune checkpoint blockade immunotherapy and related combination therapies.

Authors: Cheng, Huijuan, Sun, Guodong, Chen, Hao, Li, Yu, Han, Zhijian, Li, Yangbing, Zhang, Peng, Yang, Luxi, Li, Yumin

Year: 2019

Venue: American journal of cancer research

Paper Bispecific antibodies targeting CTLA-4: game-changer troopers in cancer immunotherapy.

Farhangnia, Pooya, Ghomi, Shamim Mollazadeh, Akbarpour, Mahzad, Delbandi, Ali-Akbar · 2023 · Frontiers in immunology · DOI

Full title: Bispecific antibodies targeting CTLA-4: game-changer troopers in cancer immunotherapy.

Authors: Farhangnia, Pooya, Ghomi, Shamim Mollazadeh, Akbarpour, Mahzad, Delbandi, Ali-Akbar

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1155778

Paper Combination therapy with immune checkpoint inhibitors in colorectal cancer: Challenges, resistance mechanisms, and the role of microbiota.

Rahimi, Ali, Baghernejadan, Zeinab, Hazrati, Ali, Malekpour, Kosar, Samimi, Leila Nejatbakhsh, Najafi, Alireza, Falak, Reza, Khorramdelazad, Hossein · 2025 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Combination therapy with immune checkpoint inhibitors in colorectal cancer: Challenges, resistance mechanisms, and the role of microbiota.

Authors: Rahimi, Ali, Baghernejadan, Zeinab, Hazrati, Ali, Malekpour, Kosar, Samimi, Leila Nejatbakhsh, Najafi, Alireza, Falak, Reza, Khorramdelazad, Hossein

Year: 2025

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2025.118014

Paper Recent Advancements in Immunotherapy for the Treatment of Metastatic Breast Cancer.

Madhu Krishna, B, Garg, Pankaj, Ramisetty, Sravani, Nair, Meera, Singhal, Sharad S · 2025 · Cancer treatment and research · DOI

Full title: Recent Advancements in Immunotherapy for the Treatment of Metastatic Breast Cancer.

Authors: Madhu Krishna, B, Garg, Pankaj, Ramisetty, Sravani, Nair, Meera, Singhal, Sharad S

Year: 2025

Venue: Cancer treatment and research

DOI: https://doi.org/10.1007/978-3-031-97242-3_3

Paper Neoantigen cancer vaccine augments anti-CTLA-4 efficacy.

Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio · 2022 · NPJ vaccines · DOI

Full title: Neoantigen cancer vaccine augments anti-CTLA-4 efficacy.

Authors: Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio

Year: 2022

Venue: NPJ vaccines

DOI: https://doi.org/10.1038/s41541-022-00433-9

Paper Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy compounds.

Wang, Haiyan, Li, Shasha, Wang, Qianyu, Jin, Zhengshuo, Shao, Wei, Gao, Yan, Li, Lu, Lin, Kequan, Zhu, Lin, Wang, Huili, Liao, Xuebin, Wang, Dong · 2021 · Science advances · DOI

Full title: Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy compounds.

Authors: Wang, Haiyan, Li, Shasha, Wang, Qianyu, Jin, Zhengshuo, Shao, Wei, Gao, Yan, Li, Lu, Lin, Kequan, Zhu, Lin, Wang, Huili, Liao, Xuebin, Wang, Dong

Year: 2021

Venue: Science advances

DOI: https://doi.org/10.1126/sciadv.abd7851

Paper The Role of Immunotherapy in Hepatocellular Carcinoma: A Systematic Review and Pooled Analysis of 2,402 Patients.

Ziogas, Ioannis A, Evangeliou, Alexandros P, Giannis, Dimitrios, Hayat, Muhammad H, Mylonas, Konstantinos S, Tohme, Samer, Geller, David A, Elias, Nahel, Goyal, Lipika, Tsoulfas, Georgios · 2021 · The oncologist · DOI

Full title: The Role of Immunotherapy in Hepatocellular Carcinoma: A Systematic Review and Pooled Analysis of 2,402 Patients.

Authors: Ziogas, Ioannis A, Evangeliou, Alexandros P, Giannis, Dimitrios, Hayat, Muhammad H, Mylonas, Konstantinos S, Tohme, Samer, Geller, David A, Elias, Nahel, Goyal, Lipika, Tsoulfas, Georgios

Year: 2021

Venue: The oncologist

DOI: https://doi.org/10.1002/onco.13638

Paper Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model.

Yu, Ping, Steel, Jason C, Zhang, Meili, Morris, John C, Waitz, Rebecca, Fasso, Marcella, Allison, James P, Waldmann, Thomas A · 2012 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model.

Authors: Yu, Ping, Steel, Jason C, Zhang, Meili, Morris, John C, Waitz, Rebecca, Fasso, Marcella, Allison, James P, Waldmann, Thomas A

Year: 2012

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1203479109

Paper Breaking immune tolerance by targeting CD25+ regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer.

Klyushnenkova, Elena N, Riabov, Vladimir B, Kouiavskaia, Diana V, Wietsma, Ashley, Zhan, Min, Alexander, Richard B · 2014 · The Prostate · DOI

Full title: Breaking immune tolerance by targeting CD25+ regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer.

Authors: Klyushnenkova, Elena N, Riabov, Vladimir B, Kouiavskaia, Diana V, Wietsma, Ashley, Zhan, Min, Alexander, Richard B

Year: 2014

Venue: The Prostate

DOI: https://doi.org/10.1002/pros.22858

Paper 913 A murine gastric cancer YTN16 model for the rational design of combination immunotherapy

Nagaoka, Koji, Sun, Changbo, Kobayashi, Yukari, Kakimi, Kazuhiro · 2021 · Regular and Young Investigator Award Abstracts · DOI

Full title: 913 A murine gastric cancer YTN16 model for the rational design of combination immunotherapy

Authors: Nagaoka, Koji, Sun, Changbo, Kobayashi, Yukari, Kakimi, Kazuhiro

Year: 2021

Venue: Regular and Young Investigator Award Abstracts

DOI: https://doi.org/10.1136/jitc-2021-sitc2021.913

Paper Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: the desmoid tumors.

Chae, Young Kwang, Othus, Megan, Patel, Sandip, Powers, Benjamin, Hsueh, Chung-Tsen, Govindarajan, Rangaswamy, Bucur, Silvana, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles, Kurzrock, Razelle · 2024 · Journal for immunotherapy of cancer · DOI

Full title: Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: the desmoid tumors.

Authors: Chae, Young Kwang, Othus, Megan, Patel, Sandip, Powers, Benjamin, Hsueh, Chung-Tsen, Govindarajan, Rangaswamy, Bucur, Silvana, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles, Kurzrock, Razelle

Year: 2024

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-009128

Paper Unmasking the immune recognition of prostate cancer with CTLA4 blockade.

Kwek, Serena S, Cha, Edward, Fong, Lawrence · 2012 · Nature reviews. Cancer · DOI

Full title: Unmasking the immune recognition of prostate cancer with CTLA4 blockade.

Authors: Kwek, Serena S, Cha, Edward, Fong, Lawrence

Year: 2012

Venue: Nature reviews. Cancer

DOI: https://doi.org/10.1038/nrc3223

Paper Combination Immunotherapy Superior to Monotherapy in Patients with Melanoma.

Doyle, Chase · 2015 · American health & drug benefits

Full title: Combination Immunotherapy Superior to Monotherapy in Patients with Melanoma.

Authors: Doyle, Chase

Year: 2015

Venue: American health & drug benefits

Paper The role of immunotherapy in small cell lung cancer.

Calles, A, Aguado, G, Sandoval, C, Álvarez, R · 2019 · Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · DOI

Full title: The role of immunotherapy in small cell lung cancer.

Authors: Calles, A, Aguado, G, Sandoval, C, Álvarez, R

Year: 2019

Venue: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

DOI: https://doi.org/10.1007/s12094-018-02011-9

Paper Clinical value of neutrophil-to-lymphocyte ratio in patients with non-small-cell lung cancer treated with PD-1/PD-L1 inhibitors.

Jiang, Tao, Bai, Yuchen, Zhou, Fei, Li, Wei, Gao, Guanghui, Su, Chunxia, Ren, Shengxiang, Chen, Xiaoxia, Zhou, Caicun · 2019 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: Clinical value of neutrophil-to-lymphocyte ratio in patients with non-small-cell lung cancer treated with PD-1/PD-L1 inhibitors.

Authors: Jiang, Tao, Bai, Yuchen, Zhou, Fei, Li, Wei, Gao, Guanghui, Su, Chunxia, Ren, Shengxiang, Chen, Xiaoxia, Zhou, Caicun

Year: 2019

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2019.02.009

Paper Incidence rate and treatment strategy of immune checkpoint inhibitor mediated hepatotoxicity: A systematic review.

Miao, Kang, Zhang, Li · 2023 · Cancer pathogenesis and therapy · DOI

Full title: Incidence rate and treatment strategy of immune checkpoint inhibitor mediated hepatotoxicity: A systematic review.

Authors: Miao, Kang, Zhang, Li

Year: 2023

Venue: Cancer pathogenesis and therapy

DOI: https://doi.org/10.1016/j.cpt.2022.11.003

Paper Genetic basis for clinical response to CTLA-4 blockade in melanoma.

Snyder, Alexandra, Makarov, Vladimir, Merghoub, Taha, Yuan, Jianda, Zaretsky, Jesse M, Desrichard, Alexis, Walsh, Logan A, Postow, Michael A, Wong, Phillip, Ho, Teresa S, Hollmann, Travis J, Bruggeman, Cameron, Kannan, Kasthuri, Li, Yanyun, Elipenahli, Ceyhan, Liu, Cailian, Harbison, Christopher T, Wang, Lisu, Ribas, Antoni, Wolchok, Jedd D, Chan, Timothy A · 2014 · The New England journal of medicine · DOI

Full title: Genetic basis for clinical response to CTLA-4 blockade in melanoma.

Authors: Snyder, Alexandra, Makarov, Vladimir, Merghoub, Taha, Yuan, Jianda, Zaretsky, Jesse M, Desrichard, Alexis, Walsh, Logan A, Postow, Michael A, Wong, Phillip, Ho, Teresa S, Hollmann, Travis J, Bruggeman, Cameron, Kannan, Kasthuri, Li, Yanyun, Elipenahli, Ceyhan, Liu, Cailian, Harbison, Christopher T, Wang, Lisu, Ribas, Antoni, Wolchok, Jedd D, Chan, Timothy A

Year: 2014

Venue: The New England journal of medicine

DOI: https://doi.org/10.1056/NEJMoa1406498

Paper PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly immunogenic head and neck squamous cell carcinoma.

Jordanides, Pete P, Jagadeesha, Sushmitha, Upadhaya, Puja, Ryan, Nathan M, Anderson, Kelvin, Lamenza, Felipe F, Shrestha, Suvekshya, Siddiqui, Arham, Bopp, Anna R, Pracha, Sherefuddin H, Roth, Peyton, Kehres, Reegan, Mo, Xiaokui, Oghumu, Steve · 2026 · Cancer biology & therapy · DOI

Full title: PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly immunogenic head and neck squamous cell carcinoma.

Authors: Jordanides, Pete P, Jagadeesha, Sushmitha, Upadhaya, Puja, Ryan, Nathan M, Anderson, Kelvin, Lamenza, Felipe F, Shrestha, Suvekshya, Siddiqui, Arham, Bopp, Anna R, Pracha, Sherefuddin H, Roth, Peyton, Kehres, Reegan, Mo, Xiaokui, Oghumu, Steve

Year: 2026

Venue: Cancer biology & therapy

DOI: https://doi.org/10.1080/15384047.2025.2600701

Paper Efficacy of PD-1/PD-L1 inhibitors in patients with non-small cell lung cancer and brain metastases: A real-world retrospective study in China.

Sheng, Jiamin, Li, Hui, Yu, Xiaoqing, Yu, Sizhe, Chen, Kaiyan, Pan, Guoqiang, Xie, Mingying, Li, Na, Zhou, Zichao, Fan, Yun · 2021 · Thoracic cancer · DOI

Full title: Efficacy of PD-1/PD-L1 inhibitors in patients with non-small cell lung cancer and brain metastases: A real-world retrospective study in China.

Authors: Sheng, Jiamin, Li, Hui, Yu, Xiaoqing, Yu, Sizhe, Chen, Kaiyan, Pan, Guoqiang, Xie, Mingying, Li, Na, Zhou, Zichao, Fan, Yun

Year: 2021

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.14171

Paper The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D. · 2016 · Nature Reviews Clinical Oncology · DOI

Full title: The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Authors: Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D.

Year: 2016

Venue: Nature Reviews Clinical Oncology

DOI: https://doi.org/10.1038/nrclinonc.2016.25

Paper Treating Colorectal Cancer with Immunotherapy: Implications for Single versus Combination Therapy.

Karki, Sophiya, Umar, Shahid, Kasi, Anup · 2020 · Current colorectal cancer reports · DOI

Full title: Treating Colorectal Cancer with Immunotherapy: Implications for Single versus Combination Therapy.

Authors: Karki, Sophiya, Umar, Shahid, Kasi, Anup

Year: 2020

Venue: Current colorectal cancer reports

DOI: https://doi.org/10.1007/s11888-020-00459-y

Paper Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou · 2023 · DOI

Full title: Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Authors: Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou

Year: 2023

DOI: https://doi.org/10.1158/0008-5472.c.6711188.v2

Paper MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints.

Wei, Jun, Nduom, Edjah K, Kong, Ling-Yuan, Hashimoto, Yuuri, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Fuller, Greg N, Gilbert, Mark R, Overwijk, Willem, Calin, George A, Heimberger, Amy B · 2016 · Neuro-oncology · DOI

Full title: MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints.

Authors: Wei, Jun, Nduom, Edjah K, Kong, Ling-Yuan, Hashimoto, Yuuri, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Fuller, Greg N, Gilbert, Mark R, Overwijk, Willem, Calin, George A, Heimberger, Amy B

Year: 2016

Venue: Neuro-oncology

DOI: https://doi.org/10.1093/neuonc/nov292

Paper Anti-PD-1 alone or in combination with anti-CTLA-4 for advanced melanoma patients with liver metastases.

Pires da Silva, Ines, Li, Isabel, Ugurel, Selma, Serra-Bellver, Patricio, Andhale, Avanti, Burnette, Hannah, Aya, Francisco, Conway, Jordan W, Braden, Jorja, Carlino, Matteo S, Menzies, Alexander M, Weichenthal, Michael, Mohr, Peter, Gutzmer, Ralf, Arance, Ana M, Johnson, Douglas B, Lorigan, Paul, Schadendorf, Dirk, Lo, Serigne N, Long, Georgina V · 2024 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Anti-PD-1 alone or in combination with anti-CTLA-4 for advanced melanoma patients with liver metastases.

Authors: Pires da Silva, Ines, Li, Isabel, Ugurel, Selma, Serra-Bellver, Patricio, Andhale, Avanti, Burnette, Hannah, Aya, Francisco, Conway, Jordan W, Braden, Jorja, Carlino, Matteo S, Menzies, Alexander M, Weichenthal, Michael, Mohr, Peter, Gutzmer, Ralf, Arance, Ana M, Johnson, Douglas B, Lorigan, Paul, Schadendorf, Dirk, Lo, Serigne N, Long, Georgina V

Year: 2024

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2024.114101

Paper A multicenter, open-label phase Ib/II study of cadonilimab (anti PD-1 and CTLA-4 bispecific antibody) monotherapy in previously treated advanced non-small-cell lung cancer (AK104-202 study).

Zhao, Yuanyuan, Ma, Yuxiang, Fan, Yun, Zhou, Jianya, Yang, Nong, Yu, Qitao, Zhuang, Wu, Song, Weifeng, Wang, Zhongmin Maxwell, Li, Baiyong, Xia, Yu, Zhao, Hongyun, Zhang, Li · 2023 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: A multicenter, open-label phase Ib/II study of cadonilimab (anti PD-1 and CTLA-4 bispecific antibody) monotherapy in previously treated advanced non-small-cell lung cancer (AK104-202 study).

Authors: Zhao, Yuanyuan, Ma, Yuxiang, Fan, Yun, Zhou, Jianya, Yang, Nong, Yu, Qitao, Zhuang, Wu, Song, Weifeng, Wang, Zhongmin Maxwell, Li, Baiyong, Xia, Yu, Zhao, Hongyun, Zhang, Li

Year: 2023

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2023.107355

Paper Interleukin 10-Mediated Response and Correlated Anemia in a Patient with Advanced Non-Small Cell Lung Carcinoma

Choucair, Khalil, Kelso, Jesse D., Duff, Joseph R., Cassidy, Christine S., Albrethsen, Mary, Ashraf, Mushtaq, Verghese, Cherian, Oft, Martin, Brunicardi, F. Charles, Dworkin, Lance D., Nemunaitis, John · 2019 · Case Reports in Oncology · DOI

Full title: Interleukin 10-Mediated Response and Correlated Anemia in a Patient with Advanced Non-Small Cell Lung Carcinoma

Authors: Choucair, Khalil, Kelso, Jesse D., Duff, Joseph R., Cassidy, Christine S., Albrethsen, Mary, Ashraf, Mushtaq, Verghese, Cherian, Oft, Martin, Brunicardi, F. Charles, Dworkin, Lance D., Nemunaitis, John

Year: 2019

Venue: Case Reports in Oncology

DOI: https://doi.org/10.1159/000499704

Paper Incidence of Hyper Progressive Disease in Combination Immunotherapy and Anti-Programmed Cell Death Protein 1/Programmed Death-Ligand 1 Monotherapy for Unresectable Hepatocellular Carcinoma

Aoki, Tomoko, Kudo, Masatoshi, Ueshima, Kazuomi, Morita, Masahiro, Chishina, Hirokazu, Takita, Masahiro, Hagiwara, Satoru, Ida, Hiroshi, Minami, Yasunori, Tsurusaki, Masakatsu, Nishida, Naoshi · 2023 · Liver Cancer · DOI

Full title: Incidence of Hyper Progressive Disease in Combination Immunotherapy and Anti-Programmed Cell Death Protein 1/Programmed Death-Ligand 1 Monotherapy for Unresectable Hepatocellular Carcinoma

Authors: Aoki, Tomoko, Kudo, Masatoshi, Ueshima, Kazuomi, Morita, Masahiro, Chishina, Hirokazu, Takita, Masahiro, Hagiwara, Satoru, Ida, Hiroshi, Minami, Yasunori, Tsurusaki, Masakatsu, Nishida, Naoshi

Year: 2023

Venue: Liver Cancer

DOI: https://doi.org/10.1159/000531024

Paper Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou · 2023 · DOI

Full title: Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer

Authors: Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou

Year: 2023

DOI: https://doi.org/10.1158/0008-5472.c.6711188

Paper High pre-treatment neutrophil-to-lymphocyte ratio as a prognostic marker for worse survival in patients with recurrent/metastatic cervical cancer treated with immune checkpoint inhibitors.

Calo, Corinne A, Barrington, David A, Brown, Morgan, Gonzalez, Lynette, Baek, Jae, Huffman, Allison, Benedict, Jason, Backes, Floor, Chambers, Laura, Cohn, David, Copeland, Larry, Cosgrove, Casey, Nagel, Christa, O'Malley, David, Bixel, Kristin · 2022 · Gynecologic oncology reports · DOI

Full title: High pre-treatment neutrophil-to-lymphocyte ratio as a prognostic marker for worse survival in patients with recurrent/metastatic cervical cancer treated with immune checkpoint inhibitors.

Authors: Calo, Corinne A, Barrington, David A, Brown, Morgan, Gonzalez, Lynette, Baek, Jae, Huffman, Allison, Benedict, Jason, Backes, Floor, Chambers, Laura, Cohn, David, Copeland, Larry, Cosgrove, Casey, Nagel, Christa, O'Malley, David, Bixel, Kristin

Year: 2022

Venue: Gynecologic oncology reports

DOI: https://doi.org/10.1016/j.gore.2022.101040

Paper [Advances in Immunotherapy of Malignant Melanoma].

Krajsová, I · 2017 · Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti · DOI

Full title: [Advances in Immunotherapy of Malignant Melanoma].

Authors: Krajsová, I

Year: 2017

Venue: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

DOI: https://doi.org/10.14735/amko20173S40

Paper Efficacy and safety data for checkpoint inhibitors in advanced melanoma under real-life conditions: A monocentric study conducted in Nice from 2010 to 2016.

Taquin, H, Fontas, E, Massol, O, Chevallier, P, Balloti, R, Beranger, G, Lacour, J-P, Passeron, T, Montaudié, H · 2018 · Annales de dermatologie et de venereologie · DOI

Full title: Efficacy and safety data for checkpoint inhibitors in advanced melanoma under real-life conditions: A monocentric study conducted in Nice from 2010 to 2016.

Authors: Taquin, H, Fontas, E, Massol, O, Chevallier, P, Balloti, R, Beranger, G, Lacour, J-P, Passeron, T, Montaudié, H

Year: 2018

Venue: Annales de dermatologie et de venereologie

DOI: https://doi.org/10.1016/j.annder.2018.06.008

Paper Pneumatosis intestinalis in cancer patients who received immune checkpoint inhibitors.

Sperling, Gabriel, Shatila, Malek, Varatharajalu, Krishnavathan, Lu, Yang, Altan, Mehmet, Zhou, Yan, Zhao, Dan, De Toni, Enrico N, Török, Helga-Paula, Schneider, Bryan J, Khan, Anam, Thomas, Anusha S, Zhang, Hao Chi, Shafi, Mehnaz A, Wang, Yinghong · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Pneumatosis intestinalis in cancer patients who received immune checkpoint inhibitors.

Authors: Sperling, Gabriel, Shatila, Malek, Varatharajalu, Krishnavathan, Lu, Yang, Altan, Mehmet, Zhou, Yan, Zhao, Dan, De Toni, Enrico N, Török, Helga-Paula, Schneider, Bryan J, Khan, Anam, Thomas, Anusha S, Zhang, Hao Chi, Shafi, Mehnaz A, Wang, Yinghong

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-023-05461-z

Paper Discordant Response to Nivolumab Plus Ipilimumab and Identification of BRAF V600E Mutation in Biphasic Malignant Pleural Mesothelioma: Case Report.

Wilkins, Olivia, Omogbehin, Adedamola, Bergquist, Peter J, Kim, Chul, Liu, Stephen V, Reuss, Joshua E · 2025 · JTO clinical and research reports · DOI

Full title: Discordant Response to Nivolumab Plus Ipilimumab and Identification of BRAF V600E Mutation in Biphasic Malignant Pleural Mesothelioma: Case Report.

Authors: Wilkins, Olivia, Omogbehin, Adedamola, Bergquist, Peter J, Kim, Chul, Liu, Stephen V, Reuss, Joshua E

Year: 2025

Venue: JTO clinical and research reports

DOI: https://doi.org/10.1016/j.jtocrr.2025.100820

Paper Cutaneous immune-related adverse events to checkpoint inhibitors.

Malviya, Neeta, Tattersall, Ian W, Leventhal, Jonathan, Alloo, Allireza · 2020 · Clinics in dermatology · DOI

Full title: Cutaneous immune-related adverse events to checkpoint inhibitors.

Authors: Malviya, Neeta, Tattersall, Ian W, Leventhal, Jonathan, Alloo, Allireza

Year: 2020

Venue: Clinics in dermatology

DOI: https://doi.org/10.1016/j.clindermatol.2020.06.011

Paper Blocking CTLA-4 promotes pressure overload-induced heart failure via activating Th17 cells.

Shang, An-Qi, Yu, Chang-Jiang, Bi, Xin, Jiang, Wei-Wei, Zhao, Ming-Luan, Sun, Yu, Guan, Hong, Zhang, Zhi-Ren · 2024 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · DOI

Full title: Blocking CTLA-4 promotes pressure overload-induced heart failure via activating Th17 cells.

Authors: Shang, An-Qi, Yu, Chang-Jiang, Bi, Xin, Jiang, Wei-Wei, Zhao, Ming-Luan, Sun, Yu, Guan, Hong, Zhang, Zhi-Ren

Year: 2024

Venue: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

DOI: https://doi.org/10.1096/fj.202400384R

Paper Real‐world efficacy and toxicity of combined nivolumab and ipilimumab in patients with metastatic melanoma

Parakh, Sagun, Randhawa, Manreet, Nguyen, Bella, Warburton, Lydia, Hussain, Mohammad Akhtar, Cebon, Jonathan, Millward, Michael, Yip, Desmond, Ali, Sayed · 2018 · Asia-Pacific Journal of Clinical Oncology · DOI

Full title: Real‐world efficacy and toxicity of combined nivolumab and ipilimumab in patients with metastatic melanoma

Authors: Parakh, Sagun, Randhawa, Manreet, Nguyen, Bella, Warburton, Lydia, Hussain, Mohammad Akhtar, Cebon, Jonathan, Millward, Michael, Yip, Desmond, Ali, Sayed

Year: 2018

Venue: Asia-Pacific Journal of Clinical Oncology

DOI: https://doi.org/10.1111/ajco.13100

Paper Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.

Trinh, Beckey, Sanchez, Guacimara Ortega, Herzig, Petra, Läubli, Heinz · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.

Authors: Trinh, Beckey, Sanchez, Guacimara Ortega, Herzig, Petra, Läubli, Heinz

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0528-x

Paper 342 A phase 3 study (COSMIC-313) of cabozantinib in combination with nivolumab and ipilimumab in patients with previously untreated advanced renal cell carcinoma of intermediate or poor risk

T. Choueiri, L. Albiges, T. Powles, N. Mohamed, Fong Wang, R. Motzer · 2020 · DOI

Full title: 342 A phase 3 study (COSMIC-313) of cabozantinib in combination with nivolumab and ipilimumab in patients with previously untreated advanced renal cell carcinoma of intermediate or poor risk

Authors: T. Choueiri, L. Albiges, T. Powles, N. Mohamed, Fong Wang, R. Motzer

Year: 2020

DOI: https://doi.org/10.1136/jitc-2020-sitc2020.0342

Paper Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cell Lung Cancer.

Park, Song Ee, Lee, Se Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Sun, Jong-Mu · 2018 · Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · DOI

Full title: Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cell Lung Cancer.

Authors: Park, Song Ee, Lee, Se Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Sun, Jong-Mu

Year: 2018

Venue: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

DOI: https://doi.org/10.1016/j.jtho.2017.10.011

Paper Expression patterns of PD-L1 and other immune checkpoint molecules in gastric cancer.

Kenichi Nakamura, K. Hatakeyama, Tetsuro Toriumi, Yusuke Koseki, Yuhei Waki, Keiichi Fujiya, S. Kamiya, R. Makuuchi, Y. Tanizawa, E. Bando, T. Kawamura, K. Yamaguchi, M. Terashima · 2019 · Journal of Clinical Oncology · DOI

Full title: Expression patterns of PD-L1 and other immune checkpoint molecules in gastric cancer.

Authors: Kenichi Nakamura, K. Hatakeyama, Tetsuro Toriumi, Yusuke Koseki, Yuhei Waki, Keiichi Fujiya, S. Kamiya, R. Makuuchi, Y. Tanizawa, E. Bando, T. Kawamura, K. Yamaguchi, M. Terashima

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.4_suppl.49

Paper Combination Immunotherapy with Cytotoxic T-Lymphocyte-Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Prevents Postoperative Breast Tumor Recurrence and Metastasis.

Sun, Ting, Zhang, Wenjia, Li, Yuan, Jin, Zhengyu, Du, Yang, Tian, Jie, Xue, Huadan · 2020 · Molecular cancer therapeutics · DOI

Full title: Combination Immunotherapy with Cytotoxic T-Lymphocyte-Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Prevents Postoperative Breast Tumor Recurrence and Metastasis.

Authors: Sun, Ting, Zhang, Wenjia, Li, Yuan, Jin, Zhengyu, Du, Yang, Tian, Jie, Xue, Huadan

Year: 2020

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-19-0495

Paper Adverse Event Profiles of Anti-CTLA-4 and Anti-PD-1 Monoclonal Antibodies Alone or in Combination: Analysis of Spontaneous Reports Submitted to FAERS.

Ji, Huan-Huan, Tang, Xue-Wen, Dong, Zhi, Song, Lin, Jia, Yun-Tao · 2019 · Clinical drug investigation · DOI

Full title: Adverse Event Profiles of Anti-CTLA-4 and Anti-PD-1 Monoclonal Antibodies Alone or in Combination: Analysis of Spontaneous Reports Submitted to FAERS.

Authors: Ji, Huan-Huan, Tang, Xue-Wen, Dong, Zhi, Song, Lin, Jia, Yun-Tao

Year: 2019

Venue: Clinical drug investigation

DOI: https://doi.org/10.1007/s40261-018-0735-0

Paper Enlighting the Shadow for Advanced Hepatocellular Carcinoma: Immunotherapy with Immune Checkpoint Inhibitors.

Sahin, Berksoy · 2017 · Journal of gastrointestinal cancer · DOI

Full title: Enlighting the Shadow for Advanced Hepatocellular Carcinoma: Immunotherapy with Immune Checkpoint Inhibitors.

Authors: Sahin, Berksoy

Year: 2017

Venue: Journal of gastrointestinal cancer

DOI: https://doi.org/10.1007/s12029-017-9996-8

Paper Therapeutic cancer vaccines and combination immunotherapies involving vaccination

Nguyen, T, Urban, J, Kalinski, P · 2014 · SHILAP Revista de lepidopterología

Full title: Therapeutic cancer vaccines and combination immunotherapies involving vaccination

Authors: Nguyen, T, Urban, J, Kalinski, P

Year: 2014

Venue: SHILAP Revista de lepidopterología

Paper Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen.

Cappelli, Laura C, Brahmer, Julie R, Forde, Patrick M, Le, Dung T, Lipson, Evan J, Naidoo, Jarushka, Zheng, Lei, Bingham, Clifton O, Shah, Ami A · 2018 · Seminars in arthritis and rheumatism · DOI

Full title: Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen.

Authors: Cappelli, Laura C, Brahmer, Julie R, Forde, Patrick M, Le, Dung T, Lipson, Evan J, Naidoo, Jarushka, Zheng, Lei, Bingham, Clifton O, Shah, Ami A

Year: 2018

Venue: Seminars in arthritis and rheumatism

DOI: https://doi.org/10.1016/j.semarthrit.2018.02.011

Paper Current and emerging trends in prostate cancer immunotherapy.

Schatz, Adam, Mian, Badar M · 2019 · Asian journal of andrology · DOI

Full title: Current and emerging trends in prostate cancer immunotherapy.

Authors: Schatz, Adam, Mian, Badar M

Year: 2019

Venue: Asian journal of andrology

DOI: https://doi.org/10.4103/aja.aja_52_17

Paper Tumor-Activated Carrier-Free Prodrug Nanoparticles for Targeted Cancer Immunotherapy: Preclinical Evidence for Safe and Effective Drug Delivery.

Man Kyu Shim, Suah Yang, In-Cheol Sun, Kwangmeyung Kim · 2022 · Advanced Drug Delivery Reviews · DOI

Full title: Tumor-Activated Carrier-Free Prodrug Nanoparticles for Targeted Cancer Immunotherapy: Preclinical Evidence for Safe and Effective Drug Delivery.

Authors: Man Kyu Shim, Suah Yang, In-Cheol Sun, Kwangmeyung Kim

Year: 2022

Venue: Advanced Drug Delivery Reviews

DOI: https://doi.org/10.1016/j.addr.2022.114177

Paper Autoimmune polyradiculitis due to combination immunotherapy with ipilimumab and nivolumab for the treatment of metastatic melanoma.

Lasocki, Arian, Smith, Kortnye · 2020 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · DOI

Full title: Autoimmune polyradiculitis due to combination immunotherapy with ipilimumab and nivolumab for the treatment of metastatic melanoma.

Authors: Lasocki, Arian, Smith, Kortnye

Year: 2020

Venue: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

DOI: https://doi.org/10.1016/j.jocn.2020.01.055

Paper Combination immunotherapy of nivolumab plus ipilimumab in a lung cancer patient with Werner syndrome; a case report.

Ikematsu, Yuki, Izumi, Miiru, Katahira, Katsuyuki, Ueno, Tsuyoshi, Moriuchi, Yuki, Ose, Mizuko, Noda, Naotaka, Hara, Makiko, Otsuka, Junji, Wakamatsu, Kentaro, Kawasaki, Masayuki · 2022 · Respiratory medicine case reports · DOI

Full title: Combination immunotherapy of nivolumab plus ipilimumab in a lung cancer patient with Werner syndrome; a case report.

Authors: Ikematsu, Yuki, Izumi, Miiru, Katahira, Katsuyuki, Ueno, Tsuyoshi, Moriuchi, Yuki, Ose, Mizuko, Noda, Naotaka, Hara, Makiko, Otsuka, Junji, Wakamatsu, Kentaro, Kawasaki, Masayuki

Year: 2022

Venue: Respiratory medicine case reports

DOI: https://doi.org/10.1016/j.rmcr.2022.101642

Paper PD-1/L1 With or Without CTLA-4 Inhibitors Versus Chemotherapy in Advanced Non-Small Cell Lung Cancer.

Guo, Luyong, Liang, Jiali, Dai, Wei, Li, Jiayu, Si, Yuexiu, Ren, Wei, Lu, Yan, Chen, Danqi · 2022 · Cancer control : journal of the Moffitt Cancer Center · DOI

Full title: PD-1/L1 With or Without CTLA-4 Inhibitors Versus Chemotherapy in Advanced Non-Small Cell Lung Cancer.

Authors: Guo, Luyong, Liang, Jiali, Dai, Wei, Li, Jiayu, Si, Yuexiu, Ren, Wei, Lu, Yan, Chen, Danqi

Year: 2022

Venue: Cancer control : journal of the Moffitt Cancer Center

DOI: https://doi.org/10.1177/10732748221107590

Paper Abstract PR05: Combination therapy with anti-CTLA4 and anti-PD1 leads to distinct immunologic changes in-vivo

Das, Rituparna, Verma, Rakesh, Sznol, Mario, Boddupalli, Chadra Sekhar, Gettinger, Scott, Kluger, Harriet M., Dhodapkar, Madhav V., Dhodapkar, Kavita M. · 2015 · Cancer Research · DOI

Full title: Abstract PR05: Combination therapy with anti-CTLA4 and anti-PD1 leads to distinct immunologic changes in-vivo

Authors: Das, Rituparna, Verma, Rakesh, Sznol, Mario, Boddupalli, Chadra Sekhar, Gettinger, Scott, Kluger, Harriet M., Dhodapkar, Madhav V., Dhodapkar, Kavita M.

Year: 2015

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.mel2014-pr05

Paper Immunotherapy and Antivascular Targeted Therapy in Patients' Treatment with Concurrent Malignant Tumors after Organ Transplantation: Opportunity or Challenge.

Shen, Bairu, Guo, Zi, Huang, Peng, Tan, Minghua, Zhang, Xiaoshen, Lin, Siyao, Song, Changshan, Wang, Jiaqing, Huang, Minqian · 2022 · Journal of immunology research · DOI

Full title: Immunotherapy and Antivascular Targeted Therapy in Patients' Treatment with Concurrent Malignant Tumors after Organ Transplantation: Opportunity or Challenge.

Authors: Shen, Bairu, Guo, Zi, Huang, Peng, Tan, Minghua, Zhang, Xiaoshen, Lin, Siyao, Song, Changshan, Wang, Jiaqing, Huang, Minqian

Year: 2022

Venue: Journal of immunology research

DOI: https://doi.org/10.1155/2022/6440419

Paper [Management of immune-related adverse events during treatment with immune checkpoint inhibitors].

Queirolo, Paola, Spagnolo, Francesco · 2016 · Recenti progressi in medicina · DOI

Full title: [Management of immune-related adverse events during treatment with immune checkpoint inhibitors].

Authors: Queirolo, Paola, Spagnolo, Francesco

Year: 2016

Venue: Recenti progressi in medicina

DOI: https://doi.org/10.1701/2332.25060

Paper Immune checkpoint inhibitor-associated gastrointestinal and hepatic adverse events and their management.

Shivaji, Uday N, Jeffery, Louisa, Gui, Xianyong, Smith, Samuel C L, Ahmad, Omer F, Akbar, Ayesha, Ghosh, Subrata, Iacucci, Marietta · 2019 · Therapeutic advances in gastroenterology · DOI

Full title: Immune checkpoint inhibitor-associated gastrointestinal and hepatic adverse events and their management.

Authors: Shivaji, Uday N, Jeffery, Louisa, Gui, Xianyong, Smith, Samuel C L, Ahmad, Omer F, Akbar, Ayesha, Ghosh, Subrata, Iacucci, Marietta

Year: 2019

Venue: Therapeutic advances in gastroenterology

DOI: https://doi.org/10.1177/1756284819884196

Paper Comparative druggability of PD-1/PD-L1 inhibitors (A56, HD10): Cross-species differences in PD-L1 exposure and efficacy.

Awadasseid, Annoor, Wang, Rui, Zhang, Koutian, Zhou, Shijia, Zhang, Feng, Jin, Zeyun, Zhang, Wen · 2025 · Bioorganic & medicinal chemistry · DOI

Full title: Comparative druggability of PD-1/PD-L1 inhibitors (A56, HD10): Cross-species differences in PD-L1 exposure and efficacy.

Authors: Awadasseid, Annoor, Wang, Rui, Zhang, Koutian, Zhou, Shijia, Zhang, Feng, Jin, Zeyun, Zhang, Wen

Year: 2025

Venue: Bioorganic & medicinal chemistry

DOI: https://doi.org/10.1016/j.bmc.2025.118268

Paper Single agent vs combination immunotherapy in advanced melanoma: a review of the evidence.

Benhima, Nada, Belbaraka, Rhizlane, Langouo Fontsa, Mireille D · 2024 · Current opinion in oncology · DOI

Full title: Single agent vs combination immunotherapy in advanced melanoma: a review of the evidence.

Authors: Benhima, Nada, Belbaraka, Rhizlane, Langouo Fontsa, Mireille D

Year: 2024

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000001014

Lee, James J., Yothers, Greg, George, Thomas J., Fakih, Marwan, Mallick, Atrayee Basu, Mitchell, Edith P., Wade, James L., Krauss, John C., Kayaleh, Omar, Heron, Dwight E., Allegra, Carmen J., Lipchik, Corey, Feng, Huichen, Joy, Marion, Srinivasan, Ashok, Pogue–Geile, Katherine L., Lucas, Peter C., Warren, Sarah E., Cesano, Alessandra, Jacobs, Samuel A. · 2019 · Clinical Research (Excluding Clinical Trials) · DOI

Year: 2019

Venue: Clinical Research (Excluding Clinical Trials)

DOI: https://doi.org/10.1158/1538-7445.sabcs18-2257

Paper Icaritin promotes tumor T-cell infiltration and induces antitumor immunity in mice.

Hao, Haibang, Zhang, Qi, Zhu, Hai, Wen, Yuxiang, Qiu, Ding, Xiong, Jian, Fu, Xiaolan, Wu, Yuzhang, Meng, Kun, Li, Jian · 2019 · European journal of immunology · DOI

Full title: Icaritin promotes tumor T-cell infiltration and induces antitumor immunity in mice.

Authors: Hao, Haibang, Zhang, Qi, Zhu, Hai, Wen, Yuxiang, Qiu, Ding, Xiong, Jian, Fu, Xiaolan, Wu, Yuzhang, Meng, Kun, Li, Jian

Year: 2019

Venue: European journal of immunology

DOI: https://doi.org/10.1002/eji.201948225

Paper Bronchiolitis after Combination Immunotherapy With Ipilimumab and Nivolumab in a Melanoma Patient.

Basir, Shahir, Bosiers, Jana, Westgeest, Hans M, Yick, David C Y, van Werven, Jochem R, van der Leest, Cor H · 2024 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Bronchiolitis after Combination Immunotherapy With Ipilimumab and Nivolumab in a Melanoma Patient.

Authors: Basir, Shahir, Bosiers, Jana, Westgeest, Hans M, Yick, David C Y, van Werven, Jochem R, van der Leest, Cor H

Year: 2024

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000509

Paper P1.11.42 Dual Immune Checkpoint Blockade With CTLA-4 and PD-(L)1 Inhibitors in NSCLC: A Reconstructed Patient Data Meta-Analysis

Federico, Alessandro Di, Stumpo, Sara, Mantuano, Francesco, Giglio, Andrea De, Bianco, Francesco, Pecci, F., Alessi, J.V., Wang, Xueliang, Sperandi, Francesca, Melotti, Barbara, Gelsomino, F., Skoulidis, Ferdinandos, Garassino, Marina Chiara, Peters, S., Awad, M.M., Ardizzoni, A., Ricciuti, B. · 2025 · Journal of Thoracic Oncology · DOI

Full title: P1.11.42 Dual Immune Checkpoint Blockade With CTLA-4 and PD-(L)1 Inhibitors in NSCLC: A Reconstructed Patient Data Meta-Analysis

Authors: Federico, Alessandro Di, Stumpo, Sara, Mantuano, Francesco, Giglio, Andrea De, Bianco, Francesco, Pecci, F., Alessi, J.V., Wang, Xueliang, Sperandi, Francesca, Melotti, Barbara, Gelsomino, F., Skoulidis, Ferdinandos, Garassino, Marina Chiara, Peters, S., Awad, M.M., Ardizzoni, A., Ricciuti, B.

Year: 2025

Venue: Journal of Thoracic Oncology

DOI: https://doi.org/10.1016/j.jtho.2025.09.342

Paper [Roles of Programmed Cell Death-1/Programmed Cell Death-ligand 1 and Cytotoxic T-lymphocyte-associated Protein 4 Signaling Pathways in Bladder Urothelial Carcinoma].

Lin, Xian Zhi, Chen, Feng Jiang, Guo, Yong · 2019 · Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae · DOI

Full title: [Roles of Programmed Cell Death-1/Programmed Cell Death-ligand 1 and Cytotoxic T-lymphocyte-associated Protein 4 Signaling Pathways in Bladder Urothelial Carcinoma].

Authors: Lin, Xian Zhi, Chen, Feng Jiang, Guo, Yong

Year: 2019

Venue: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

DOI: https://doi.org/10.3881/j.issn.1000-503X.11442

Paper Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer.

Mestrallet, Guillaume, Brown, Matthew, Vaninov, Natalie, Cho, Nam Woo, Velazquez, Leandra, Ananthanarayanan, Aparna, Spitzer, Matthew, Vabret, Nicolas, Bozkus, Cansu Cimen, Samstein, Robert M, Bhardwaj, Nina · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer.

Authors: Mestrallet, Guillaume, Brown, Matthew, Vaninov, Natalie, Cho, Nam Woo, Velazquez, Leandra, Ananthanarayanan, Aparna, Spitzer, Matthew, Vabret, Nicolas, Bozkus, Cansu Cimen, Samstein, Robert M, Bhardwaj, Nina

Year: 2025

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2025.02.12.637954

Paper Immune checkpoint inhibitors win the 2018 Nobel Prize.

Huang, Pei-Wei, Chang, John Wen-Cheng · 2019 · Biomedical journal · DOI

Full title: Immune checkpoint inhibitors win the 2018 Nobel Prize.

Authors: Huang, Pei-Wei, Chang, John Wen-Cheng

Year: 2019

Venue: Biomedical journal

DOI: https://doi.org/10.1016/j.bj.2019.09.002

Paper NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy.

Sottile, Rosa, Tannazi, Milad, Johansson, Maria H, Cristiani, Costanza Maria, Calabró, Luana, Ventura, Valeria, Cutaia, Ornella, Chiarucci, Carla, Covre, Alessia, Garofalo, Cinzia, Pontén, Victor, Tallerico, Rossana, Frumento, Paolo, Micke, Patrick, Maio, Michele, Kärre, Klas, Carbone, Ennio · 2019 · International journal of cancer · DOI

Full title: NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy.

Authors: Sottile, Rosa, Tannazi, Milad, Johansson, Maria H, Cristiani, Costanza Maria, Calabró, Luana, Ventura, Valeria, Cutaia, Ornella, Chiarucci, Carla, Covre, Alessia, Garofalo, Cinzia, Pontén, Victor, Tallerico, Rossana, Frumento, Paolo, Micke, Patrick, Maio, Michele, Kärre, Klas, Carbone, Ennio

Year: 2019

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.32363

Paper Checkpoint inhibitors in head and neck cancer

Ilson Sepúlveda, R. Ascui, A. Andrés Capizzano · 2019 · memo - Magazine of European Medical Oncology · DOI

Full title: Checkpoint inhibitors in head and neck cancer

Authors: Ilson Sepúlveda, R. Ascui, A. Andrés Capizzano

Year: 2019

Venue: memo - Magazine of European Medical Oncology

DOI: https://doi.org/10.1007/s12254-019-0511-8

Paper Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA.

Abou‐Alfa, Ghassan K., Chan, Stephen L., Kudo, Masatoshi, Lau, George, Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, He, Philip, Negro, Alejandra, Sangro, Bruno · 2022 · Journal of Clinical Oncology · DOI

Full title: Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA.

Authors: Abou‐Alfa, Ghassan K., Chan, Stephen L., Kudo, Masatoshi, Lau, George, Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, He, Philip, Negro, Alejandra, Sangro, Bruno

Year: 2022

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2022.40.4_suppl.379

Paper Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer.

Benzon, Benjamin, Glavaris, Stephanie A, Simons, Brian W, Hughes, Robert M, Ghabili, Kamyar, Mullane, Patrick, Miller, Rebecca, Nugent, Katriana, Shinder, Brian, Tosoian, Jeffrey, Fuchs, Ephraim J, Tran, Phuoc T, Hurley, Paula J, Vuica-Ross, Milena, Schaeffer, Edward M, Drake, Charles G, Ross, Ashley E · 2018 · Prostate cancer and prostatic diseases · DOI

Full title: Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer.

Authors: Benzon, Benjamin, Glavaris, Stephanie A, Simons, Brian W, Hughes, Robert M, Ghabili, Kamyar, Mullane, Patrick, Miller, Rebecca, Nugent, Katriana, Shinder, Brian, Tosoian, Jeffrey, Fuchs, Ephraim J, Tran, Phuoc T, Hurley, Paula J, Vuica-Ross, Milena, Schaeffer, Edward M, Drake, Charles G, Ross, Ashley E

Year: 2018

Venue: Prostate cancer and prostatic diseases

DOI: https://doi.org/10.1038/s41391-018-0035-z

Paper Management of Adverse Events Following Treatment With Anti-Programmed Death-1 Agents.

Weber, Jeffrey S, Postow, Michael, Lao, Christopher D, Schadendorf, Dirk · 2016 · The oncologist · DOI

Full title: Management of Adverse Events Following Treatment With Anti-Programmed Death-1 Agents.

Authors: Weber, Jeffrey S, Postow, Michael, Lao, Christopher D, Schadendorf, Dirk

Year: 2016

Venue: The oncologist

DOI: https://doi.org/10.1634/theoncologist.2016-0055

Paper HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development.

Arab, Atefeh, Yazdian-Robati, Rezvan, Behravan, Javad · 2020 · Archivum immunologiae et therapiae experimentalis · DOI

Full title: HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development.

Authors: Arab, Atefeh, Yazdian-Robati, Rezvan, Behravan, Javad

Year: 2020

Venue: Archivum immunologiae et therapiae experimentalis

DOI: https://doi.org/10.1007/s00005-019-00566-1

Paper Immunotherapy in Older Adults With Advanced Cancers: Implications for Clinical Decision-Making and Future Research

Kanesvaran, Ravindran, Córdoba, Raúl, Maggiore, Ronald J. · 2018 · American Society of Clinical Oncology Educational Book · DOI

Full title: Immunotherapy in Older Adults With Advanced Cancers: Implications for Clinical Decision-Making and Future Research

Authors: Kanesvaran, Ravindran, Córdoba, Raúl, Maggiore, Ronald J.

Year: 2018

Venue: American Society of Clinical Oncology Educational Book

DOI: https://doi.org/10.1200/edbk_201435

Paper Activated CTLA-4-independent immunosuppression of Treg cells disturbs CTLA-4 blockade-mediated antitumor immunity.

Watanabe, Tomofumi, Ishino, Takamasa, Ueda, Youki, Nagasaki, Joji, Sadahira, Takuya, Dansako, Hiromichi, Araki, Motoo, Togashi, Yosuke · 2023 · Cancer science · DOI

Full title: Activated CTLA-4-independent immunosuppression of Treg cells disturbs CTLA-4 blockade-mediated antitumor immunity.

Authors: Watanabe, Tomofumi, Ishino, Takamasa, Ueda, Youki, Nagasaki, Joji, Sadahira, Takuya, Dansako, Hiromichi, Araki, Motoo, Togashi, Yosuke

Year: 2023

Venue: Cancer science

DOI: https://doi.org/10.1111/cas.15756

Paper Patterns of immune-related adverse events in patients treated for various cancer types with immune checkpoint inhibitors.

Slaught, Matthew J, Kaakour, Dalia, Azizi, Armon, Kroening, Gianna, Chen, Wen-Pin, Mar, Nataliya, Valerin, Jennifer B · 2026 · Future oncology (London, England) · DOI

Full title: Patterns of immune-related adverse events in patients treated for various cancer types with immune checkpoint inhibitors.

Authors: Slaught, Matthew J, Kaakour, Dalia, Azizi, Armon, Kroening, Gianna, Chen, Wen-Pin, Mar, Nataliya, Valerin, Jennifer B

Year: 2026

Venue: Future oncology (London, England)

DOI: https://doi.org/10.1080/14796694.2025.2600910

Paper Interview with Thomas Powles: The use of durvalumab in urothelial cancer - the latest strides in immuno-oncology.

Powles, Thomas · 2017 · Future oncology (London, England) · DOI

Full title: Interview with Thomas Powles: The use of durvalumab in urothelial cancer - the latest strides in immuno-oncology.

Authors: Powles, Thomas

Year: 2017

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2017-0207

Paper PD-1 checkpoint blockade alone or combined PD-1 and CTLA-4 blockade as immunotherapy for lung cancer?

Tanvetyanon, Tawee, Gray, Jhanelle E, Antonia, Scott J · 2017 · Expert opinion on biological therapy · DOI

Full title: PD-1 checkpoint blockade alone or combined PD-1 and CTLA-4 blockade as immunotherapy for lung cancer?

Authors: Tanvetyanon, Tawee, Gray, Jhanelle E, Antonia, Scott J

Year: 2017

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2017.1280454

Paper [Brain tumor immunotherapy: Illusion or hope?].

Migliorini, Denis, Dutoit, Valérie, Walker, Paul R, Dietrich, Pierre-Yves · 2017 · Bulletin du cancer · DOI

Full title: [Brain tumor immunotherapy: Illusion or hope?].

Authors: Migliorini, Denis, Dutoit, Valérie, Walker, Paul R, Dietrich, Pierre-Yves

Year: 2017

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2017.01.014

Paper Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor–Induced Raynaud's-Like Phenomenon

Khan, Shaheen, Itzstein, Mitchell S. von, Lü, Rong, Bermas, Bonnie L., Karp, David R., Khan, Saad A., Fattah, Farjana, Park, Jason Y., Saltarski, Jessica M., Gloria-McCutchen, Yvonne, Xie, Yang, Li, Quan‐Zhen, Wakeland, Edward K., Gerber, David E. · 2020 · The Oncologist · DOI

Full title: Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor–Induced Raynaud's-Like Phenomenon

Authors: Khan, Shaheen, Itzstein, Mitchell S. von, Lü, Rong, Bermas, Bonnie L., Karp, David R., Khan, Saad A., Fattah, Farjana, Park, Jason Y., Saltarski, Jessica M., Gloria-McCutchen, Yvonne, Xie, Yang, Li, Quan‐Zhen, Wakeland, Edward K., Gerber, David E.

Year: 2020

Venue: The Oncologist

DOI: https://doi.org/10.1634/theoncologist.2019-0666

Paper Side-effects of checkpoint inhibitor-based combination therapy.

Kourie, Hampig R, Klastersky, Jean A · 2016 · Current opinion in oncology · DOI

Full title: Side-effects of checkpoint inhibitor-based combination therapy.

Authors: Kourie, Hampig R, Klastersky, Jean A

Year: 2016

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000295

Paper Abstract 611: PD-1-based combination immunotherapy reinvigorates CD8+ T cells in metastatic pancreatic cancer patients with improved survival

Wu, Annie A., Tsujikawa, Takahiro, Choe, Gina, Beechwood, Teresa, Coussens, Lisa M., Durham, Jennifer N., Jaffee, Elizabeth M., Le, Dung T. · 2018 · Cancer Research · DOI

Full title: Abstract 611: PD-1-based combination immunotherapy reinvigorates CD8+ T cells in metastatic pancreatic cancer patients with improved survival

Authors: Wu, Annie A., Tsujikawa, Takahiro, Choe, Gina, Beechwood, Teresa, Coussens, Lisa M., Durham, Jennifer N., Jaffee, Elizabeth M., Le, Dung T.

Year: 2018

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2018-611

Paper Revealing anti-PD-1 resistance mechanisms in HCC: A path towards novel combination immunotherapies

Bárcena‐Varela, Marina · 2022 · Journal of Hepatology · DOI

Full title: Revealing anti-PD-1 resistance mechanisms in HCC: A path towards novel combination immunotherapies

Authors: Bárcena‐Varela, Marina

Year: 2022

Venue: Journal of Hepatology

DOI: https://doi.org/10.1016/j.jhep.2022.04.020

Paper Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.

Mitsui, Jun, Nishikawa, Hiroyoshi, Muraoka, Daisuke, Wang, Linan, Noguchi, Takuro, Sato, Eiichi, Kondo, Satoshi, Allison, James P, Sakaguchi, Shimon, Old, Lloyd J, Kato, Takuma, Shiku, Hiroshi · 2010 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.

Authors: Mitsui, Jun, Nishikawa, Hiroyoshi, Muraoka, Daisuke, Wang, Linan, Noguchi, Takuro, Sato, Eiichi, Kondo, Satoshi, Allison, James P, Sakaguchi, Shimon, Old, Lloyd J, Kato, Takuma, Shiku, Hiroshi

Year: 2010

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-09-3243

Paper Checkpoint inhibitors and gastrointestinal immune-related adverse events.

Pernot, Simon, Ramtohul, Toulsie, Taieb, Julien · 2016 · Current opinion in oncology · DOI

Full title: Checkpoint inhibitors and gastrointestinal immune-related adverse events.

Authors: Pernot, Simon, Ramtohul, Toulsie, Taieb, Julien

Year: 2016

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000292

Paper Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)

Kim, J.M., Chen, Daniel S. · 2016 · Annals of Oncology · DOI

Full title: Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)

Authors: Kim, J.M., Chen, Daniel S.

Year: 2016

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdw217

Paper Update on immunotherapy for renal cancer.

Canales Rojas, Rodrigo · 2021 · Medwave · DOI

Full title: Update on immunotherapy for renal cancer.

Authors: Canales Rojas, Rodrigo

Year: 2021

Venue: Medwave

DOI: https://doi.org/10.5867/medwave.2021.05.8202

Paper Optimizing combination immunotherapy in lung cancer.

Danovi, Safia · 2024 · Nature genetics · DOI

Full title: Optimizing combination immunotherapy in lung cancer.

Authors: Danovi, Safia

Year: 2024

Venue: Nature genetics

DOI: https://doi.org/10.1038/s41588-024-02011-2

Paper The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck cancer.

Dua, Divyanshu, Kelly, Charles, Kovarik, Josef, Iqbal, Muhammad Shahid · 2022 · Asia-Pacific journal of clinical oncology · DOI

Full title: The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck cancer.

Authors: Dua, Divyanshu, Kelly, Charles, Kovarik, Josef, Iqbal, Muhammad Shahid

Year: 2022

Venue: Asia-Pacific journal of clinical oncology

DOI: https://doi.org/10.1111/ajco.13583

Paper The risk of diarrhea and colitis in patients with lung cancer treated with immune checkpoint inhibitors: a systematic review and meta-analysis.

Bishay, K, Tandon, P, Bourassa-Blanchette, S, Laurie, S A, McCurdy, J D · 2020 · Current oncology (Toronto, Ont.) · DOI

Full title: The risk of diarrhea and colitis in patients with lung cancer treated with immune checkpoint inhibitors: a systematic review and meta-analysis.

Authors: Bishay, K, Tandon, P, Bourassa-Blanchette, S, Laurie, S A, McCurdy, J D

Year: 2020

Venue: Current oncology (Toronto, Ont.)

DOI: https://doi.org/10.3747/co.27.6251

Paper [Not Available].

Mateus, Christine, Libenciuc, Cristina, Robert, Caroline · 2016 · Bulletin du cancer · DOI

Full title: [Not Available].

Authors: Mateus, Christine, Libenciuc, Cristina, Robert, Caroline

Year: 2016

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/S0007-4551(16)30140-0

Paper Gotistobart in combination with pembrolizumab in patients with advanced melanoma who have progressed on PD-1 inhibitors with or without CTLA-4 inhibitors.

S. Hu-Lieskovan, Kari L. Kendra, Kai He, B. Doonan, Eric S. Schaefer, Edward Arrowsmith, K. Chung, Eric D Whitman, U. Vaishampayan, S. Shpyro, Qiong Wang, Juanjuan Su, Chris P. Leung, K. Kai, Yang Liu, P. Zheng, Tianhong Li · 2025 · Journal of Clinical Oncology · DOI

Full title: Gotistobart in combination with pembrolizumab in patients with advanced melanoma who have progressed on PD-1 inhibitors with or without CTLA-4 inhibitors.

Authors: S. Hu-Lieskovan, Kari L. Kendra, Kai He, B. Doonan, Eric S. Schaefer, Edward Arrowsmith, K. Chung, Eric D Whitman, U. Vaishampayan, S. Shpyro, Qiong Wang, Juanjuan Su, Chris P. Leung, K. Kai, Yang Liu, P. Zheng, Tianhong Li

Year: 2025

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2025.43.16_suppl.9551

Paper Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model.

Ghosh, Sanjana, He, Xuedan, Huang, Wei-Chiao, Lovell, Jonathan F · 2022 · APL bioengineering · DOI

Full title: Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model.

Authors: Ghosh, Sanjana, He, Xuedan, Huang, Wei-Chiao, Lovell, Jonathan F

Year: 2022

Venue: APL bioengineering

DOI: https://doi.org/10.1063/5.0099811

Paper A Phase III Study of Durvalumab (MEDI4736) With or Without Tremelimumab for Previously Treated Patients With Advanced NSCLC: Rationale and Protocol Design of the ARCTIC Study.

Planchard, David, Yokoi, Takashi, McCleod, Michael J, Fischer, Jürgen R, Kim, Young-Chul, Ballas, Marc, Shi, Kelvin, Soria, Jean-Charles · 2016 · Clinical lung cancer · DOI

Full title: A Phase III Study of Durvalumab (MEDI4736) With or Without Tremelimumab for Previously Treated Patients With Advanced NSCLC: Rationale and Protocol Design of the ARCTIC Study.

Authors: Planchard, David, Yokoi, Takashi, McCleod, Michael J, Fischer, Jürgen R, Kim, Young-Chul, Ballas, Marc, Shi, Kelvin, Soria, Jean-Charles

Year: 2016

Venue: Clinical lung cancer

DOI: https://doi.org/10.1016/j.cllc.2016.03.003

Paper CD47 Blockade and Cowpea Mosaic Virus Nanoparticle In Situ Vaccination Triggers Phagocytosis and Tumor Killing

Wang, Chao, Steinmetz, Nicole F. · 2019 · Advanced Healthcare Materials · DOI

Full title: CD47 Blockade and Cowpea Mosaic Virus Nanoparticle In Situ Vaccination Triggers Phagocytosis and Tumor Killing

Authors: Wang, Chao, Steinmetz, Nicole F.

Year: 2019

Venue: Advanced Healthcare Materials

DOI: https://doi.org/10.1002/adhm.201801288

Paper Atypical metastatic lung cancer of the right ventricle on FDG PET/CT.

Jiang, James Yuheng, Lee, Marco, Kang, Christine, Wong, Veronica Chi Ken, Mansberg, Robert · 2021 · Radiology case reports · DOI

Full title: Atypical metastatic lung cancer of the right ventricle on FDG PET/CT.

Authors: Jiang, James Yuheng, Lee, Marco, Kang, Christine, Wong, Veronica Chi Ken, Mansberg, Robert

Year: 2021

Venue: Radiology case reports

DOI: https://doi.org/10.1016/j.radcr.2021.07.092

Paper The Prognostic Value of Albumin-Globulin Ratio and Eosinophil-Neutrophil Ratio in Patients with Advanced Tumors Undergoing Treatment with PD-1/PD-L1 Inhibitors.

Ma, Yan, Shang, Kun, Wu, Shanshan, Wang, Jing, Cao, Bangwei · 2022 · Nutrition and cancer · DOI

Full title: The Prognostic Value of Albumin-Globulin Ratio and Eosinophil-Neutrophil Ratio in Patients with Advanced Tumors Undergoing Treatment with PD-1/PD-L1 Inhibitors.

Authors: Ma, Yan, Shang, Kun, Wu, Shanshan, Wang, Jing, Cao, Bangwei

Year: 2022

Venue: Nutrition and cancer

DOI: https://doi.org/10.1080/01635581.2022.2032764

Paper Clinical assessment of immune-related adverse events.

Sosa, Aaron, Lopez Cadena, Esther, Simon Olive, Cristina, Karachaliou, Niki, Rosell, Rafael · 2018 · Therapeutic advances in medical oncology · DOI

Full title: Clinical assessment of immune-related adverse events.

Authors: Sosa, Aaron, Lopez Cadena, Esther, Simon Olive, Cristina, Karachaliou, Niki, Rosell, Rafael

Year: 2018

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758835918764628

Paper 1156 Small circular RNA vaccines for combination cancer immunotherapy

Zhu, Guizhi · 2024 · Regular and Young Investigator Award Abstracts · DOI

Full title: 1156 Small circular RNA vaccines for combination cancer immunotherapy

Authors: Zhu, Guizhi

Year: 2024

Venue: Regular and Young Investigator Award Abstracts

DOI: https://doi.org/10.1136/jitc-2024-sitc2024.1156

Paper Immune Therapy for Sarcomas.

Anderson, Peter M · 2017 · Advances in experimental medicine and biology · DOI

Full title: Immune Therapy for Sarcomas.

Authors: Anderson, Peter M

Year: 2017

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-319-53156-4_6

Paper Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab to probodies and bispecific molecules targeting the tumor microenvironment.

Lisi, Lucia, Lacal, Pedro Miguel, Martire, Maria, Navarra, Pierluigi, Graziani, Grazia · 2022 · Pharmacological research · DOI

Full title: Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab to probodies and bispecific molecules targeting the tumor microenvironment.

Authors: Lisi, Lucia, Lacal, Pedro Miguel, Martire, Maria, Navarra, Pierluigi, Graziani, Grazia

Year: 2022

Venue: Pharmacological research

DOI: https://doi.org/10.1016/j.phrs.2021.105997

Paper Therapeutic combinations of immune-modulating antibodies in melanoma and beyond.

Cohen, Justine, Sznol, Mario · 2015 · Seminars in oncology · DOI

Full title: Therapeutic combinations of immune-modulating antibodies in melanoma and beyond.

Authors: Cohen, Justine, Sznol, Mario

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.02.014

Paper Nivolumab and ipilimumab: immunotherapy for treatment of malignant melanoma.

Carreau, Nicole A, Pavlick, Anna C · 2019 · Future oncology (London, England) · DOI

Full title: Nivolumab and ipilimumab: immunotherapy for treatment of malignant melanoma.

Authors: Carreau, Nicole A, Pavlick, Anna C

Year: 2019

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2018-0607

Paper Targeting adenosine for cancer immunotherapy

Leone, Robert D., Emens, Leisha A. · 2018 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Targeting adenosine for cancer immunotherapy

Authors: Leone, Robert D., Emens, Leisha A.

Year: 2018

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-018-0360-8

Paper Endocrine, Sexual Function, and Infertility Side Effects of Immune Checkpoint Inhibitor Therapy for Genitourinary Cancers.

Sood, Akshay, Cole, Daniel, Abdollah, Firas, Eilender, Ben, Roumayah, Zade, Deebajah, Mustafa, Dabaja, Ali, Alanee, Shaheen · 2018 · Current urology reports · DOI

Full title: Endocrine, Sexual Function, and Infertility Side Effects of Immune Checkpoint Inhibitor Therapy for Genitourinary Cancers.

Authors: Sood, Akshay, Cole, Daniel, Abdollah, Firas, Eilender, Ben, Roumayah, Zade, Deebajah, Mustafa, Dabaja, Ali, Alanee, Shaheen

Year: 2018

Venue: Current urology reports

DOI: https://doi.org/10.1007/s11934-018-0819-7

Paper NSABP FC-9: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (D) plus tremelimumab (T) following palliative hypofractionated radiotherapy (SBRT) in patients (pts) with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) progressing on chemotherapy.

Lee, James J., Yothers, Greg, George, Thomas J., Fakih, Marwan, Mallick, Atrayee Basu, Maalouf, Bassam, Krauss, John C., Heron, Dwight E., Allegra, Carmen J., Jacobs, Samuel A. · 2018 · Journal of Clinical Oncology · DOI

Full title: NSABP FC-9: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (D) plus tremelimumab (T) following palliative hypofractionated radiotherapy (SBRT) in patients (pts) with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) progressing on chemotherapy.

Authors: Lee, James J., Yothers, Greg, George, Thomas J., Fakih, Marwan, Mallick, Atrayee Basu, Maalouf, Bassam, Krauss, John C., Heron, Dwight E., Allegra, Carmen J., Jacobs, Samuel A.

Year: 2018

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2018.36.15_suppl.e15681

Paper Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma.

Qin, Qian, Nan, Xinyu, Miller, Tara, Fisher, Ronald, Teh, Bin, Pandita, Shruti, Farach, Andrew M, Pingali, Sai Ravi, Pandita, Raj K, Butler, E Brian, Pandita, Tej K, Iyer, Swaminathan P · 2018 · Radiation research · DOI

Full title: Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma.

Authors: Qin, Qian, Nan, Xinyu, Miller, Tara, Fisher, Ronald, Teh, Bin, Pandita, Shruti, Farach, Andrew M, Pingali, Sai Ravi, Pandita, Raj K, Butler, E Brian, Pandita, Tej K, Iyer, Swaminathan P

Year: 2018

Venue: Radiation research

DOI: https://doi.org/10.1667/RR15048.1

Paper Autoimmune Cardiotoxicity of Cancer Immunotherapy.

Cheng, Feixiong, Loscalzo, Joseph · 2017 · Trends in immunology · DOI

Full title: Autoimmune Cardiotoxicity of Cancer Immunotherapy.

Authors: Cheng, Feixiong, Loscalzo, Joseph

Year: 2017

Venue: Trends in immunology

DOI: https://doi.org/10.1016/j.it.2016.11.007

Paper Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma: A Swedish retrospective real-world study (NEO-MEL).

A. Nelson, E. Krabbe, Karl Björksrtöm, Braslav Jovanovic, Christian U Blank, G. Ullenhag, H. Helgadottir, L. Ny, R. Olofsson Bagge · 2025 · Journal of Clinical Oncology · DOI

Full title: Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma: A Swedish retrospective real-world study (NEO-MEL).

Authors: A. Nelson, E. Krabbe, Karl Björksrtöm, Braslav Jovanovic, Christian U Blank, G. Ullenhag, H. Helgadottir, L. Ny, R. Olofsson Bagge

Year: 2025

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2025.43.16_suppl.e21563

Paper COMBINATION IMMUNOTHERAPY IN METASTATIC RENAL CELL CARCINOMA

Sepe, Pierangela, Ottini, Arianna, Verzoni, Elena, Guadalupi, Valentina, Claps, Mélanie, Procopio, Giuseppe · 2021 · Annals of Research in Oncology · DOI

Full title: COMBINATION IMMUNOTHERAPY IN METASTATIC RENAL CELL CARCINOMA

Authors: Sepe, Pierangela, Ottini, Arianna, Verzoni, Elena, Guadalupi, Valentina, Claps, Mélanie, Procopio, Giuseppe

Year: 2021

Venue: Annals of Research in Oncology

DOI: https://doi.org/10.48286/aro.2021.10

Paper Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy.

Riviere, Clément, Aljieli, Muna, Mévélec, Marie-Noëlle, Lantier, Louis, Boursin, Fanny, Lajoie, Laurie, Ducournau, Céline, Germon, Stéphanie, Moiré, Nathalie, Dimier-Poisson, Isabelle, Aubrey, Nicolas, di Tommaso, Anne · 2025 · Molecular therapy. Oncology · DOI

Full title: Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy.

Authors: Riviere, Clément, Aljieli, Muna, Mévélec, Marie-Noëlle, Lantier, Louis, Boursin, Fanny, Lajoie, Laurie, Ducournau, Céline, Germon, Stéphanie, Moiré, Nathalie, Dimier-Poisson, Isabelle, Aubrey, Nicolas, di Tommaso, Anne

Year: 2025

Venue: Molecular therapy. Oncology

DOI: https://doi.org/10.1016/j.omton.2025.200968

Paper PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer

S. Qamar, U. Chaudhary · 2017 · DOI

Full title: PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer

Authors: S. Qamar, U. Chaudhary

Year: 2017

DOI: https://doi.org/10.11648/j.jctr.20170505.11

Paper Abstract B12: Immune checkpoint blockade to improve T cell infiltration and function in colorectal cancer

Kodumudi, Krithika N., Charles, James, Luu, Carrie, Mullinax, John E., Li, Julie, Hall, MacLean, Weber, Amy, Sarnaik, Amod A., Pilon‐Thomas, Shari · 2017 · Cancer Research · DOI

Full title: Abstract B12: Immune checkpoint blockade to improve T cell infiltration and function in colorectal cancer

Authors: Kodumudi, Krithika N., Charles, James, Luu, Carrie, Mullinax, John E., Li, Julie, Hall, MacLean, Weber, Amy, Sarnaik, Amod A., Pilon‐Thomas, Shari

Year: 2017

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.crc16-b12

Paper Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival.

Yamada, Kentaro, Sawada, Tsunaki, Nakamura, Masanao, Yamamura, Takeshi, Maeda, Keiko, Ishikawa, Eri, Iida, Tadashi, Mizutani, Yasuyuki, Kakushima, Naomi, Ishikawa, Takuya, Furukawa, Kazuhiro, Ohno, Eizaburo, Honda, Takashi, Kawashima, Hiroki, Ishigami, Masatoshi, Furune, Satoshi, Hase, Tetsunari, Yokota, Kenji, Maeda, Osamu, Hashimoto, Naozumi, Akiyama, Masashi, Ando, Yuichi, Fujishiro, Mitsuhiro · 2021 · World journal of gastroenterology · DOI

Full title: Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival.

Authors: Yamada, Kentaro, Sawada, Tsunaki, Nakamura, Masanao, Yamamura, Takeshi, Maeda, Keiko, Ishikawa, Eri, Iida, Tadashi, Mizutani, Yasuyuki, Kakushima, Naomi, Ishikawa, Takuya, Furukawa, Kazuhiro, Ohno, Eizaburo, Honda, Takashi, Kawashima, Hiroki, Ishigami, Masatoshi, Furune, Satoshi, Hase, Tetsunari, Yokota, Kenji, Maeda, Osamu, Hashimoto, Naozumi, Akiyama, Masashi, Ando, Yuichi, Fujishiro, Mitsuhiro

Year: 2021

Venue: World journal of gastroenterology

DOI: https://doi.org/10.3748/wjg.v27.i41.7190

Paper PD-1/PD-L1 expression in pancreatic cancer and its implication in novel therapies

Adrian Mucileanu, R. Chira, P. Mircea · 2021 · Medicine and Pharmacy Reports · DOI

Full title: PD-1/PD-L1 expression in pancreatic cancer and its implication in novel therapies

Authors: Adrian Mucileanu, R. Chira, P. Mircea

Year: 2021

Venue: Medicine and Pharmacy Reports

DOI: https://doi.org/10.15386/mpr-2116

Paper The emerging role of immune checkpoint inhibition in malignant lymphoma.

Hude, Ida, Sasse, Stephanie, Engert, Andreas, Bröckelmann, Paul J · 2017 · Haematologica · DOI

Full title: The emerging role of immune checkpoint inhibition in malignant lymphoma.

Authors: Hude, Ida, Sasse, Stephanie, Engert, Andreas, Bröckelmann, Paul J

Year: 2017

Venue: Haematologica

DOI: https://doi.org/10.3324/haematol.2016.150656

Paper Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Full title: Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Year: 2023

DOI: https://doi.org/10.1158/1078-0432.c.6528824.v1

Paper The Risk of Diarrhea and Colitis in Patients With Advanced Melanoma Undergoing Immune Checkpoint Inhibitor Therapy: A Systematic Review and Meta-Analysis.

Tandon, Parul, Bourassa-Blanchette, Samuel, Bishay, Kirles, Parlow, Simon, Laurie, Scott A, McCurdy, Jeffrey D · 2018 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: The Risk of Diarrhea and Colitis in Patients With Advanced Melanoma Undergoing Immune Checkpoint Inhibitor Therapy: A Systematic Review and Meta-Analysis.

Authors: Tandon, Parul, Bourassa-Blanchette, Samuel, Bishay, Kirles, Parlow, Simon, Laurie, Scott A, McCurdy, Jeffrey D

Year: 2018

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000213

Paper Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.

Avogadri, Francesca, Zappasodi, Roberta, Yang, Arvin, Budhu, Sadna, Malandro, Nicole, Hirschhorn-Cymerman, Daniel, Tiwari, Shakuntala, Maughan, Maureen F, Olmsted, Robert, Wolchok, Jedd D, Merghoub, Taha · 2014 · Cancer immunology research · DOI

Full title: Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.

Authors: Avogadri, Francesca, Zappasodi, Roberta, Yang, Arvin, Budhu, Sadna, Malandro, Nicole, Hirschhorn-Cymerman, Daniel, Tiwari, Shakuntala, Maughan, Maureen F, Olmsted, Robert, Wolchok, Jedd D, Merghoub, Taha

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0220

Paper Association between changes in thioredoxin reductase and other peripheral blood biomarkers with response to PD-1 inhibitor-based combination immunotherapy in non-small cell lung cancer: a retrospective study.

Wen, Shaodi, Du, Xiaoyue, Chen, Yuzhong, Xia, Jingwei, Wang, Ruotong, Zhu, Miaolin, Peng, Weiwei, Spitaleri, Gianluca, Hofman, Paul, Bironzo, Paolo, Wang, Xin, Shen, Bo · 2022 · Translational lung cancer research · DOI

Full title: Association between changes in thioredoxin reductase and other peripheral blood biomarkers with response to PD-1 inhibitor-based combination immunotherapy in non-small cell lung cancer: a retrospective study.

Authors: Wen, Shaodi, Du, Xiaoyue, Chen, Yuzhong, Xia, Jingwei, Wang, Ruotong, Zhu, Miaolin, Peng, Weiwei, Spitaleri, Gianluca, Hofman, Paul, Bironzo, Paolo, Wang, Xin, Shen, Bo

Year: 2022

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-22-300

Paper A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.

Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A, Holoweckyj, Nicholas, Bamber, Lisa, Tigue, Natalie J, Offer, Emily, Andrews, John, Yan, Li, Mullins, Stefanie, Oberst, Michael D, Coates Ulrichsen, Jane, Leinster, David A, McGlinchey, Kelly, Young, Lesley, Morrow, Michelle, Hammond, Scott A, Mallinder, Philip, Herath, Athula, Leow, Ching Ching, Wilkinson, Robert W, Stewart, Ross · 2017 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.

Authors: Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A, Holoweckyj, Nicholas, Bamber, Lisa, Tigue, Natalie J, Offer, Emily, Andrews, John, Yan, Li, Mullins, Stefanie, Oberst, Michael D, Coates Ulrichsen, Jane, Leinster, David A, McGlinchey, Kelly, Young, Lesley, Morrow, Michelle, Hammond, Scott A, Mallinder, Philip, Herath, Athula, Leow, Ching Ching, Wilkinson, Robert W, Stewart, Ross

Year: 2017

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-16-2000

Paper [Not Available].

Pagès, Franck, Granier, Clémence, Kirilovsky, Amos, Elsissy, Carine, Tartour, Eric · 2016 · Bulletin du cancer · DOI

Full title: [Not Available].

Authors: Pagès, Franck, Granier, Clémence, Kirilovsky, Amos, Elsissy, Carine, Tartour, Eric

Year: 2016

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/S0007-4551(16)30373-3

Paper Combination immunotherapy with ipilimumab and nivolumab in patients with advanced biliary tract cancers.

Klein, Oliver, Kee, Damien, Nagrial, Adnan, Markman, Ben, Underhill, Craig, Michael, Michael, Lum, Caroline, Behren, Andreas, Palmer, Jodie, Tebbutt, Niall C., Carlino, Matteo S., Cebon, Jonathan · 2020 · Journal of Clinical Oncology · DOI

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced biliary tract cancers.

Authors: Klein, Oliver, Kee, Damien, Nagrial, Adnan, Markman, Ben, Underhill, Craig, Michael, Michael, Lum, Caroline, Behren, Andreas, Palmer, Jodie, Tebbutt, Niall C., Carlino, Matteo S., Cebon, Jonathan

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.4588

Paper Outcome of melanoma patients with elevated LDH treated with first-line targeted therapy or PD-1-based immune checkpoint inhibition.

Knispel, Sarah, Gassenmaier, Maximilian, Menzies, Alexander M, Loquai, Carmen, Johnson, Douglas B, Franklin, Cindy, Gutzmer, Ralf, Hassel, Jessica C, Weishaupt, Carsten, Eigentler, Thomas, Schilling, Bastian, Schummer, Patrick, Sirokay, Judith, Kiecker, Felix, Owen, Carina N, Fleischer, Maria I, Cann, Christopher, Kähler, Katharina C, Mohr, Peter, Bluhm, Leonie, Niebel, Dennis, Thoms, Kai-Martin, Goldinger, Simone M, Reinhardt, Lydia, Meier, Friedegund, Berking, Carola, Reinhard, Raphael, Susok, Laura, Ascierto, Paolo A, Drexler, Konstantin, Pföhler, Claudia, Tietze, Julia, Heinzerling, Lucie, Livingstone, Elisabeth, Ugurel, Selma, Long, Georgina V, Stang, Andreas, Schadendorf, Dirk, Zimmer, Lisa · 2021 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Outcome of melanoma patients with elevated LDH treated with first-line targeted therapy or PD-1-based immune checkpoint inhibition.

Authors: Knispel, Sarah, Gassenmaier, Maximilian, Menzies, Alexander M, Loquai, Carmen, Johnson, Douglas B, Franklin, Cindy, Gutzmer, Ralf, Hassel, Jessica C, Weishaupt, Carsten, Eigentler, Thomas, Schilling, Bastian, Schummer, Patrick, Sirokay, Judith, Kiecker, Felix, Owen, Carina N, Fleischer, Maria I, Cann, Christopher, Kähler, Katharina C, Mohr, Peter, Bluhm, Leonie, Niebel, Dennis, Thoms, Kai-Martin, Goldinger, Simone M, Reinhardt, Lydia, Meier, Friedegund, Berking, Carola, Reinhard, Raphael, Susok, Laura, Ascierto, Paolo A, Drexler, Konstantin, Pföhler, Claudia, Tietze, Julia, Heinzerling, Lucie, Livingstone, Elisabeth, Ugurel, Selma, Long, Georgina V, Stang, Andreas, Schadendorf, Dirk, Zimmer, Lisa

Year: 2021

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2021.01.034

Paper Combination therapy for metastatic renal cell carcinoma.

Buonerba, Carlo, Di Lorenzo, Giuseppe, Sonpavde, Guru · 2016 · Annals of translational medicine · DOI

Full title: Combination therapy for metastatic renal cell carcinoma.

Authors: Buonerba, Carlo, Di Lorenzo, Giuseppe, Sonpavde, Guru

Year: 2016

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm.2016.01.31

Paper Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma.

Afzal, Muhammad Zubair, Mercado, Rima R, Shirai, Keisuke · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma.

Authors: Afzal, Muhammad Zubair, Mercado, Rima R, Shirai, Keisuke

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0375-1

Paper VOICES: Clinical Trials Remain Essential to Evaluate Combination Immunotherapies, and Against a Broader Range of Cancers

J. Wolchok · 2013 · DOI

Full title: VOICES: Clinical Trials Remain Essential to Evaluate Combination Immunotherapies, and Against a Broader Range of Cancers

Authors: J. Wolchok

Year: 2013

DOI: https://doi.org/10.1097/01.cot.0000437978.33811.08

Paper Correlation of Peripheral Blood CD4/CD8 Ratio with Efficacy and Prognosis in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors.

Li, Guo-Xiang, Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Zhang, Min, Sun, Zhi-Gang · 2025 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP · DOI

Full title: Correlation of Peripheral Blood CD4/CD8 Ratio with Efficacy and Prognosis in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors.

Authors: Li, Guo-Xiang, Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Zhang, Min, Sun, Zhi-Gang

Year: 2025

Venue: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

DOI: https://doi.org/10.29271/jcpsp.2025.06.800

Paper Tumor Stroma Infiltrating T Cells Predict the Efficacy of Anti-CTLA-4 Antibody in NSCLC.

Saijo, Hiroshi, Hirohashi, Yoshihiko, Sumi, Toshiyuki, Shijubo, Naoki, Saito, Astushi, Honjo, Osamu, Saikai, Toyohiro, Takabatake, Hirotsugu, Fujita, Akihisa, Honda, Yasuhito, Koba, Hiroyuki, Chiba, Hirofumi, Torigoe, Toshihiko · 2026 · Anticancer research · DOI

Full title: Tumor Stroma Infiltrating T Cells Predict the Efficacy of Anti-CTLA-4 Antibody in NSCLC.

Authors: Saijo, Hiroshi, Hirohashi, Yoshihiko, Sumi, Toshiyuki, Shijubo, Naoki, Saito, Astushi, Honjo, Osamu, Saikai, Toyohiro, Takabatake, Hirotsugu, Fujita, Akihisa, Honda, Yasuhito, Koba, Hiroyuki, Chiba, Hirofumi, Torigoe, Toshihiko

Year: 2026

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.17944

Paper Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blockade in Multiple Syngeneic Murine Models of Breast and Colorectal Cancers.

Guo, Linlin, Overholser, Jay, Naylon, Sarah, Roche, Stephane, Ede, Nicholas, Kaumaya, Pravin T P · 2025 · Molecular cancer therapeutics · DOI

Full title: Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blockade in Multiple Syngeneic Murine Models of Breast and Colorectal Cancers.

Authors: Guo, Linlin, Overholser, Jay, Naylon, Sarah, Roche, Stephane, Ede, Nicholas, Kaumaya, Pravin T P

Year: 2025

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-24-0908

Paper Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.

Vétizou, Marie, Pitt, Jonathan M, Daillère, Romain, Lepage, Patricia, Waldschmitt, Nadine, Flament, Caroline, Rusakiewicz, Sylvie, Routy, Bertrand, Roberti, Maria P, Duong, Connie P M, Poirier-Colame, Vichnou, Roux, Antoine, Becharef, Sonia, Formenti, Silvia, Golden, Encouse, Cording, Sascha, Eberl, Gerard, Schlitzer, Andreas, Ginhoux, Florent, Mani, Sridhar, Yamazaki, Takahiro, Jacquelot, Nicolas, Enot, David P, Bérard, Marion, Nigou, Jérôme, Opolon, Paule, Eggermont, Alexander, Woerther, Paul-Louis, Chachaty, Elisabeth, Chaput, Nathalie, Robert, Caroline, Mateus, Christina, Kroemer, Guido, Raoult, Didier, Boneca, Ivo Gomperts, Carbonnel, Franck, Chamaillard, Mathias, Zitvogel, Laurence · 2015 · Science (New York, N.Y.) · DOI

Full title: Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.

Authors: Vétizou, Marie, Pitt, Jonathan M, Daillère, Romain, Lepage, Patricia, Waldschmitt, Nadine, Flament, Caroline, Rusakiewicz, Sylvie, Routy, Bertrand, Roberti, Maria P, Duong, Connie P M, Poirier-Colame, Vichnou, Roux, Antoine, Becharef, Sonia, Formenti, Silvia, Golden, Encouse, Cording, Sascha, Eberl, Gerard, Schlitzer, Andreas, Ginhoux, Florent, Mani, Sridhar, Yamazaki, Takahiro, Jacquelot, Nicolas, Enot, David P, Bérard, Marion, Nigou, Jérôme, Opolon, Paule, Eggermont, Alexander, Woerther, Paul-Louis, Chachaty, Elisabeth, Chaput, Nathalie, Robert, Caroline, Mateus, Christina, Kroemer, Guido, Raoult, Didier, Boneca, Ivo Gomperts, Carbonnel, Franck, Chamaillard, Mathias, Zitvogel, Laurence

Year: 2015

Venue: Science (New York, N.Y.)

DOI: https://doi.org/10.1126/science.aad1329

Paper Immune Checkpoint Inhibitors and Beyond: An Overview of Immune-Based Therapies in Merkel Cell Carcinoma.

Samimi, Mahtab · 2019 · American journal of clinical dermatology · DOI

Full title: Immune Checkpoint Inhibitors and Beyond: An Overview of Immune-Based Therapies in Merkel Cell Carcinoma.

Authors: Samimi, Mahtab

Year: 2019

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-019-00427-9

Paper Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness.

Pedicord, Virginia A, Cross, Justin R, Montalvo-Ortiz, Welby, Miller, Martin L, Allison, James P · 2015 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness.

Authors: Pedicord, Virginia A, Cross, Justin R, Montalvo-Ortiz, Welby, Miller, Martin L, Allison, James P

Year: 2015

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.1402390

Paper The age of enlightenment in melanoma immunotherapy

Albertini, Mark R. · 2018 · Journal for ImmunoTherapy of Cancer · DOI

Full title: The age of enlightenment in melanoma immunotherapy

Authors: Albertini, Mark R.

Year: 2018

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-018-0397-8

Paper Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities

A. Ganina, M. Askarov, Larissa Kozina, Madina Karimova, Y. Shayakhmetov, Perizat Mukhamedzhanova, A. Brimova, D. Berikbol, Elmira Chuvakova, L. Zaripova, Abay Baigenzhin · 2024 · Advances in Respiratory Medicine · DOI

Full title: Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities

Authors: A. Ganina, M. Askarov, Larissa Kozina, Madina Karimova, Y. Shayakhmetov, Perizat Mukhamedzhanova, A. Brimova, D. Berikbol, Elmira Chuvakova, L. Zaripova, Abay Baigenzhin

Year: 2024

Venue: Advances in Respiratory Medicine

DOI: https://doi.org/10.3390/arm92060045

Paper Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.

Ninomiya, Toshifumi, Kemmotsu, Naoya, Mukohara, Fumiaki, Magari, Masaki, Miyamoto, Ai, Ueda, Youki, Ishino, Takamasa, Nagasaki, Joji, Fujiwara, Tomohiro, Yamamoto, Hidetaka, Hayashi, Hidetoshi, Tachibana, Kota, Ishida, Joji, Otani, Yoshihiro, Tanaka, Shota, Toyooka, Shinichi, Okamoto, Isamu, Togashi, Yosuke · 2025 · Cancer research · DOI

Full title: Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.

Authors: Ninomiya, Toshifumi, Kemmotsu, Naoya, Mukohara, Fumiaki, Magari, Masaki, Miyamoto, Ai, Ueda, Youki, Ishino, Takamasa, Nagasaki, Joji, Fujiwara, Tomohiro, Yamamoto, Hidetaka, Hayashi, Hidetoshi, Tachibana, Kota, Ishida, Joji, Otani, Yoshihiro, Tanaka, Shota, Toyooka, Shinichi, Okamoto, Isamu, Togashi, Yosuke

Year: 2025

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-24-2274

Paper Reviewer #2 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: Reviewer #2 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2023

DOI: https://doi.org/10.7554/elife.87292.1.sa1

Paper 72206 - Overall Survival after Isolated Hepatic Perfusion in Combination with Ipilimumab and Nivolumab in Patients with Uveal Melanoma (SCANDIUM II trial)

A. Nelson, A. Shafazand, C. Cahlin, A. Carneiro, H. Helgadottir, M. Levin, M. Rizell, G. Ullenhag, S. Wirén, P. Lindnér, J. Nilsson, L. Ny, R. Bagge · 2024 · British Journal of Surgery · DOI

Full title: 72206 - Overall Survival after Isolated Hepatic Perfusion in Combination with Ipilimumab and Nivolumab in Patients with Uveal Melanoma (SCANDIUM II trial)

Authors: A. Nelson, A. Shafazand, C. Cahlin, A. Carneiro, H. Helgadottir, M. Levin, M. Rizell, G. Ullenhag, S. Wirén, P. Lindnér, J. Nilsson, L. Ny, R. Bagge

Year: 2024

Venue: British Journal of Surgery

DOI: https://doi.org/10.1093/bjs/znae175.032

Paper Efficacy of PD-1/PD-L1 plus CTLA-4 inhibitors in solid tumors based on clinical characteristics: a meta-analysis.

Huo, Gengwei, Liu, Wenjie, Zhang, Sipei, Chen, Peng · 2023 · Immunotherapy · DOI

Full title: Efficacy of PD-1/PD-L1 plus CTLA-4 inhibitors in solid tumors based on clinical characteristics: a meta-analysis.

Authors: Huo, Gengwei, Liu, Wenjie, Zhang, Sipei, Chen, Peng

Year: 2023

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2022-0140

Paper Paradoxical Effect of Myosteatosis on the Immune Checkpoint Inhibitor Response in Metastatic Renal Cell Carcinoma.

Yu, Jiwoong, Ahn, Hyeonju, Han, Kyung Yeon, Song, Wan, Sung, Hyun Hwan, Jeon, Hwang Gyun, Jeong, Byong Chang, Seo, Seong Il, Jeon, Seong Soo, Park, Se Hoon, Park, Woong-Yang, Lee, Ji Hyun, Kang, Minyong · 2025 · Journal of cachexia, sarcopenia and muscle · DOI

Full title: Paradoxical Effect of Myosteatosis on the Immune Checkpoint Inhibitor Response in Metastatic Renal Cell Carcinoma.

Authors: Yu, Jiwoong, Ahn, Hyeonju, Han, Kyung Yeon, Song, Wan, Sung, Hyun Hwan, Jeon, Hwang Gyun, Jeong, Byong Chang, Seo, Seong Il, Jeon, Seong Soo, Park, Se Hoon, Park, Woong-Yang, Lee, Ji Hyun, Kang, Minyong

Year: 2025

Venue: Journal of cachexia, sarcopenia and muscle

DOI: https://doi.org/10.1002/jcsm.13758

Paper Interim results from the OPTIMAL trial: A phase II clinical trial of combination nivolumab, ipilimumab, and taxane in patients with untreated metastatic non-small cell lung cancer (NSCLC).

Clarke, Jeffrey, Wang, Xiaofei F., Gu, Lin, Stevenson, Marvaretta, Stinchcombe, Tom, Ramalingam, Sundhar, Antonia, Scott, Shariff, Afreen, Garst, Jennifer, Crawford, Jeffrey, Ready, Neal · 2020 · Journal of Clinical Oncology · DOI

Full title: Interim results from the OPTIMAL trial: A phase II clinical trial of combination nivolumab, ipilimumab, and taxane in patients with untreated metastatic non-small cell lung cancer (NSCLC).

Authors: Clarke, Jeffrey, Wang, Xiaofei F., Gu, Lin, Stevenson, Marvaretta, Stinchcombe, Tom, Ramalingam, Sundhar, Antonia, Scott, Shariff, Afreen, Garst, Jennifer, Crawford, Jeffrey, Ready, Neal

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.e21683

Paper Immune Checkpoint Inhibitors in the Treatment of Patients with Neuroendocrine Neoplasia

Weber, Matthias M., Fottner, Christian · 2018 · Oncology Research and Treatment · DOI

Full title: Immune Checkpoint Inhibitors in the Treatment of Patients with Neuroendocrine Neoplasia

Authors: Weber, Matthias M., Fottner, Christian

Year: 2018

Venue: Oncology Research and Treatment

DOI: https://doi.org/10.1159/000488996

Paper Immune checkpoint inhibitor-induced interstitial lung disease with and without CTLA-4 regimen in non-small cell lung cancer patients and PD-L1 <1 %: A multicenter, retrospective study.

Murata, Daiki, Azuma, Koichi, Murotani, Kenta, Ito, Kazuhiro, Nomizo, Takashi, Yamada, Kazuhiko, Imabayashi, Tatsuya, Iwanaga, Kentaro, Chibana, Kenji, Ota, Takayo, Nishii, Yuuya, Nakao, Akira, Okada, Asuka, Hamai, Kosuke, Tanimura, Keiko, Yoshimine, Kohei, Tamura, Yosuke, Takaki, Ryuichiro, Goto, Yasuhiro, Hibino, Makoto, Oba, Tomohiro, Sumi, Toshiyuki, Kaneda, Hiroyasu, Nishioka, Naoya, Yamada, Tadaaki, Takayama, Koichi · 2025 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: Immune checkpoint inhibitor-induced interstitial lung disease with and without CTLA-4 regimen in non-small cell lung cancer patients and PD-L1 <1 %: A multicenter, retrospective study.

Authors: Murata, Daiki, Azuma, Koichi, Murotani, Kenta, Ito, Kazuhiro, Nomizo, Takashi, Yamada, Kazuhiko, Imabayashi, Tatsuya, Iwanaga, Kentaro, Chibana, Kenji, Ota, Takayo, Nishii, Yuuya, Nakao, Akira, Okada, Asuka, Hamai, Kosuke, Tanimura, Keiko, Yoshimine, Kohei, Tamura, Yosuke, Takaki, Ryuichiro, Goto, Yasuhiro, Hibino, Makoto, Oba, Tomohiro, Sumi, Toshiyuki, Kaneda, Hiroyasu, Nishioka, Naoya, Yamada, Tadaaki, Takayama, Koichi

Year: 2025

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2025.108772

Paper Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

Asrir, Assia, Tardiveau, Claire, Coudert, Juliette, Laffont, Robin, Blanchard, Lucas, Bellard, Elisabeth, Veerman, Krystle, Bettini, S., Lafouresse, Fanny, Vina, Estefania, Tarroux, Dorian, Roy, Séverine Le, Girault, Isabelle, Molinaro, Irma, Martins, Frédéric, Scoazec, Jean‐Yves, Ortéga, Nathalie, Robert, Caroline, Girard, Jean‐Philippe · 2022 · Cancer Cell · DOI

Full title: Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

Authors: Asrir, Assia, Tardiveau, Claire, Coudert, Juliette, Laffont, Robin, Blanchard, Lucas, Bellard, Elisabeth, Veerman, Krystle, Bettini, S., Lafouresse, Fanny, Vina, Estefania, Tarroux, Dorian, Roy, Séverine Le, Girault, Isabelle, Molinaro, Irma, Martins, Frédéric, Scoazec, Jean‐Yves, Ortéga, Nathalie, Robert, Caroline, Girard, Jean‐Philippe

Year: 2022

Venue: Cancer Cell

DOI: https://doi.org/10.1016/j.ccell.2022.01.002

Paper Immune checkpoint inhibition for the treatment of mesothelioma.

Nowak, Anna K, McDonnell, Alison, Cook, Alistair · 2019 · Expert opinion on biological therapy · DOI

Full title: Immune checkpoint inhibition for the treatment of mesothelioma.

Authors: Nowak, Anna K, McDonnell, Alison, Cook, Alistair

Year: 2019

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2019.1606209

Paper Combination Immunotherapy Development in Melanoma.

Eggermont, Alexander M M, Crittenden, Marka, Wargo, Jennifer · 2018 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Combination Immunotherapy Development in Melanoma.

Authors: Eggermont, Alexander M M, Crittenden, Marka, Wargo, Jennifer

Year: 2018

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.1200/EDBK_201131

Paper Immune checkpoint blockade in patients with melanoma metastatic to the brain.

Di Giacomo, Anna Maria, Margolin, Kim · 2015 · Seminars in oncology · DOI

Full title: Immune checkpoint blockade in patients with melanoma metastatic to the brain.

Authors: Di Giacomo, Anna Maria, Margolin, Kim

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.02.006

Paper Personalized cancer vaccines and their integration with standard of care modalities.

Snäkä, Tiia, Friedlaender, Alex, Graciotti, Michele, Hernandez, Miriam, Rossier, Laetitia, Kirchner, Volker, Kandalaft, Lana · 2026 · Cancer treatment reviews · DOI

Full title: Personalized cancer vaccines and their integration with standard of care modalities.

Authors: Snäkä, Tiia, Friedlaender, Alex, Graciotti, Michele, Hernandez, Miriam, Rossier, Laetitia, Kirchner, Volker, Kandalaft, Lana

Year: 2026

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2026.103095

Paper Pulmonary Toxicities from Checkpoint Immunotherapy for Malignancy.

Possick, Jennifer D · 2017 · Clinics in chest medicine · DOI

Full title: Pulmonary Toxicities from Checkpoint Immunotherapy for Malignancy.

Authors: Possick, Jennifer D

Year: 2017

Venue: Clinics in chest medicine

DOI: https://doi.org/10.1016/j.ccm.2016.12.012

Paper Combination immunotherapy approaches.

Drake, C G · 2012 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Combination immunotherapy approaches.

Authors: Drake, C G

Year: 2012

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mds262

Paper Thiopurine therapy enhances immune checkpoint inhibitor efficacy in low-mutational burden melanoma: A promising anticancer approach.

Nazerai, Loulieta, Tsiavou, Christina, Vardouli, Lina, Schmiegelow, Kjeld, De Zio, Daniela · 2025 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Thiopurine therapy enhances immune checkpoint inhibitor efficacy in low-mutational burden melanoma: A promising anticancer approach.

Authors: Nazerai, Loulieta, Tsiavou, Christina, Vardouli, Lina, Schmiegelow, Kjeld, De Zio, Daniela

Year: 2025

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2423246122

Paper Single vs. combination immunotherapeutic strategies for glioma

Chandran, Mayuri, Candolfi, Marianela, Shah, Diana, Mineharu, Yohei, Yadav, Viveka Nand, Koschmann, Carl, Asad, Antonela S., Löwenstein, Pedro R., Castro, María G. · 2017 · Expert Opinion on Biological Therapy · DOI

Full title: Single vs. combination immunotherapeutic strategies for glioma

Authors: Chandran, Mayuri, Candolfi, Marianela, Shah, Diana, Mineharu, Yohei, Yadav, Viveka Nand, Koschmann, Carl, Asad, Antonela S., Löwenstein, Pedro R., Castro, María G.

Year: 2017

Venue: Expert Opinion on Biological Therapy

DOI: https://doi.org/10.1080/14712598.2017.1305353

Paper Favorable clinical impact of histological subtype with non-small cell carcinoma-not otherwise specified in patients with non-small cell lung cancer receiving immune checkpoint inhibitors.

Hirano, Tatsuya, Tanaka, Ichidai, Morise, Masahiro, Koyama, Junji, Hashimoto, Takahiko, Hori, Kazumi, Matsuzawa, Reiko, Hori, Sho, Karube, Kennosuke, Ito, Takayasu, Sakamoto, Koji, Shindo, Yuichiro, Sato, Mitsuo, Yokoyama, Toshihiko, Kimura, Tomoki, Kondoh, Yasuhiro, Ishii, Makoto · 2026 · Respiratory investigation · DOI

Full title: Favorable clinical impact of histological subtype with non-small cell carcinoma-not otherwise specified in patients with non-small cell lung cancer receiving immune checkpoint inhibitors.

Authors: Hirano, Tatsuya, Tanaka, Ichidai, Morise, Masahiro, Koyama, Junji, Hashimoto, Takahiko, Hori, Kazumi, Matsuzawa, Reiko, Hori, Sho, Karube, Kennosuke, Ito, Takayasu, Sakamoto, Koji, Shindo, Yuichiro, Sato, Mitsuo, Yokoyama, Toshihiko, Kimura, Tomoki, Kondoh, Yasuhiro, Ishii, Makoto

Year: 2026

Venue: Respiratory investigation

DOI: https://doi.org/10.1016/j.resinv.2026.101383

Paper Predictive factors in the treatment of oral squamous cell carcinoma using PD-1/PD-L1 inhibitors.

Gao, Antian, Pan, Xiao, Yang, Xudong, Lin, Zitong · 2021 · Investigational new drugs · DOI

Full title: Predictive factors in the treatment of oral squamous cell carcinoma using PD-1/PD-L1 inhibitors.

Authors: Gao, Antian, Pan, Xiao, Yang, Xudong, Lin, Zitong

Year: 2021

Venue: Investigational new drugs

DOI: https://doi.org/10.1007/s10637-021-01082-w

Paper [Immune checkpoint antibodies increase survival in patients with metastatic melanoma].

Fløe, Louise Elkjær, Svane, Inge Marie, Bastholt, Lars, Schmidt, Henrik · 2016 · Ugeskrift for laeger

Full title: [Immune checkpoint antibodies increase survival in patients with metastatic melanoma].

Authors: Fløe, Louise Elkjær, Svane, Inge Marie, Bastholt, Lars, Schmidt, Henrik

Year: 2016

Venue: Ugeskrift for laeger

Paper LAG3 and PD1 Regulate CD8+ T Cell in Diffuse Large B-cell Lymphoma Patients

Liu, Ying, Guo, Xinhong, Zhan, Lingbo, Wang, Lei, Wang, Xinyou, Jiang, Ming · 2021 · Computational and Mathematical Methods in Medicine · DOI

Full title: LAG3 and PD1 Regulate CD8+ T Cell in Diffuse Large B-cell Lymphoma Patients

Authors: Liu, Ying, Guo, Xinhong, Zhan, Lingbo, Wang, Lei, Wang, Xinyou, Jiang, Ming

Year: 2021

Venue: Computational and Mathematical Methods in Medicine

DOI: https://doi.org/10.1155/2021/4468140

Paper Immunotherapy in upper GI malignancies.

Murphy, Adrian, Kelly, Ronan J · 2015 · Current treatment options in oncology · DOI

Full title: Immunotherapy in upper GI malignancies.

Authors: Murphy, Adrian, Kelly, Ronan J

Year: 2015

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-015-0336-6

Paper Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Hong, Dong‐Chun, Yang, Jing, Sun, Cong, Liu, Yuan-Tao, Shen, Lujun, Xu, Bu-Shu, Que, Yi, Xia, Xiaojun, Zhang, Xing · 2023 · Clinical Cancer Research · DOI

Full title: Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Authors: Hong, Dong‐Chun, Yang, Jing, Sun, Cong, Liu, Yuan-Tao, Shen, Lujun, Xu, Bu-Shu, Que, Yi, Xia, Xiaojun, Zhang, Xing

Year: 2023

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-22-3567

Paper Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition via dynamic intratumoral immune modulation.

Sugawara, Kotaro, Iwai, Miwako, Ito, Hirotaka, Tanaka, Minoru, Seto, Yasuyuki, Todo, Tomoki · 2021 · Molecular therapy oncolytics · DOI

Full title: Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition via dynamic intratumoral immune modulation.

Authors: Sugawara, Kotaro, Iwai, Miwako, Ito, Hirotaka, Tanaka, Minoru, Seto, Yasuyuki, Todo, Tomoki

Year: 2021

Venue: Molecular therapy oncolytics

DOI: https://doi.org/10.1016/j.omto.2021.05.004

Paper A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy.

Varn, Frederick S, Wang, Yue, Cheng, Chao · 2019 · Oncoimmunology · DOI

Full title: A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy.

Authors: Varn, Frederick S, Wang, Yue, Cheng, Chao

Year: 2019

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2018.1513440

Paper Immunotherapy Is Changing First-Line Treatment of Metastatic Renal-Cell Carcinoma.

Matthew K. Labriola, Kristen A. Batich, Jason Zhu, M. McNamara, M. Harrison, A. Armstrong, D. George, Tian Zhang · 2019 · Clinical Genitourinary Cancer · DOI

Full title: Immunotherapy Is Changing First-Line Treatment of Metastatic Renal-Cell Carcinoma.

Authors: Matthew K. Labriola, Kristen A. Batich, Jason Zhu, M. McNamara, M. Harrison, A. Armstrong, D. George, Tian Zhang

Year: 2019

Venue: Clinical Genitourinary Cancer

DOI: https://doi.org/10.1016/j.clgc.2019.01.017

Paper Immune induction strategies to enhance responses to PD-1 blockade: lessons from the TONIC trial

Demaria, Sandra, Romano, Emanuela, Brackstone, Muriel, Formenti, Silvia C. · 2019 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Immune induction strategies to enhance responses to PD-1 blockade: lessons from the TONIC trial

Authors: Demaria, Sandra, Romano, Emanuela, Brackstone, Muriel, Formenti, Silvia C.

Year: 2019

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-019-0783-x

Paper Nivolumab plus ipilimumab combination therapy in cancer: Current evidence to date.

Nikoo, Marzieh, Rabiee, Fatemeh, Mohebbi, Hossein, Eghbalifard, Negar, Rajabi, Hamid, Yazdani, Yalda, Sakhaei, Delaram, Khosravifarsani, Mohammadreza, Akhavan-Sigari, Reza · 2023 · International immunopharmacology · DOI

Full title: Nivolumab plus ipilimumab combination therapy in cancer: Current evidence to date.

Authors: Nikoo, Marzieh, Rabiee, Fatemeh, Mohebbi, Hossein, Eghbalifard, Negar, Rajabi, Hamid, Yazdani, Yalda, Sakhaei, Delaram, Khosravifarsani, Mohammadreza, Akhavan-Sigari, Reza

Year: 2023

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.109881

Paper Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.

Dai, Xiaoming, Bu, Xia, Gao, Yang, Guo, Jianping, Hu, Jia, Jiang, Cong, Zhang, Zhao, Xu, Kexin, Duan, Jinzhi, He, Shaohui, Zhang, Jinfang, Wan, Lixin, Liu, Tianjie, Zhou, Xiaobo, Hung, Mien-Chie, Freeman, Gordon J, Wei, Wenyi · 2021 · Molecular cell · DOI

Full title: Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.

Authors: Dai, Xiaoming, Bu, Xia, Gao, Yang, Guo, Jianping, Hu, Jia, Jiang, Cong, Zhang, Zhao, Xu, Kexin, Duan, Jinzhi, He, Shaohui, Zhang, Jinfang, Wan, Lixin, Liu, Tianjie, Zhou, Xiaobo, Hung, Mien-Chie, Freeman, Gordon J, Wei, Wenyi

Year: 2021

Venue: Molecular cell

DOI: https://doi.org/10.1016/j.molcel.2021.03.037

Paper Systemic Management of Advanced Adrenocortical Carcinoma.

Russell, Jeffery S · 2024 · Current treatment options in oncology · DOI

Full title: Systemic Management of Advanced Adrenocortical Carcinoma.

Authors: Russell, Jeffery S

Year: 2024

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-024-01249-6

Paper Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.

Newell, Felicity, Pires da Silva, Ines, Johansson, Peter A, Menzies, Alexander M, Wilmott, James S, Addala, Venkateswar, Carlino, Matteo S, Rizos, Helen, Nones, Katia, Edwards, Jarem J, Lakis, Vanessa, Kazakoff, Stephen H, Mukhopadhyay, Pamela, Ferguson, Peter M, Leonard, Conrad, Koufariotis, Lambros T, Wood, Scott, Blank, Christian U, Thompson, John F, Spillane, Andrew J, Saw, Robyn P M, Shannon, Kerwin F, Pearson, John V, Mann, Graham J, Hayward, Nicholas K, Scolyer, Richard A, Waddell, Nicola, Long, Georgina V · 2022 · Cancer cell · DOI

Full title: Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.

Authors: Newell, Felicity, Pires da Silva, Ines, Johansson, Peter A, Menzies, Alexander M, Wilmott, James S, Addala, Venkateswar, Carlino, Matteo S, Rizos, Helen, Nones, Katia, Edwards, Jarem J, Lakis, Vanessa, Kazakoff, Stephen H, Mukhopadhyay, Pamela, Ferguson, Peter M, Leonard, Conrad, Koufariotis, Lambros T, Wood, Scott, Blank, Christian U, Thompson, John F, Spillane, Andrew J, Saw, Robyn P M, Shannon, Kerwin F, Pearson, John V, Mann, Graham J, Hayward, Nicholas K, Scolyer, Richard A, Waddell, Nicola, Long, Georgina V

Year: 2022

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2021.11.012

Paper Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.

Willsmore, Zena N, Coumbe, Ben G T, Crescioli, Silvia, Reci, Sara, Gupta, Ayushi, Harris, Robert J, Chenoweth, Alicia, Chauhan, Jitesh, Bax, Heather J, McCraw, Alexa, Cheung, Anthony, Osborn, Gabriel, Hoffmann, Ricarda M, Nakamura, Mano, Laddach, Roman, Geh, Jenny L C, MacKenzie-Ross, Alastair, Healy, Ciaran, Tsoka, Sophia, Spicer, James F, Josephs, Debra H, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N · 2021 · European journal of immunology · DOI

Full title: Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.

Authors: Willsmore, Zena N, Coumbe, Ben G T, Crescioli, Silvia, Reci, Sara, Gupta, Ayushi, Harris, Robert J, Chenoweth, Alicia, Chauhan, Jitesh, Bax, Heather J, McCraw, Alexa, Cheung, Anthony, Osborn, Gabriel, Hoffmann, Ricarda M, Nakamura, Mano, Laddach, Roman, Geh, Jenny L C, MacKenzie-Ross, Alastair, Healy, Ciaran, Tsoka, Sophia, Spicer, James F, Josephs, Debra H, Papa, Sophie, Lacy, Katie E, Karagiannis, Sophia N

Year: 2021

Venue: European journal of immunology

DOI: https://doi.org/10.1002/eji.202048747

Paper How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune response with combination immunotherapy.

Linch, Stefanie N, Redmond, William L · 2016 · Journal for immunotherapy of cancer · DOI

Full title: How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune response with combination immunotherapy.

Authors: Linch, Stefanie N, Redmond, William L

Year: 2016

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-016-0135-z

Paper Recent Clinical Trials of Immunotherapy in Non-Small-Cell Lung Cancer

Gkolfinopoulos, Stavros, Mountzios, Giannis · 2019 · Immunotherapy · DOI

Full title: Recent Clinical Trials of Immunotherapy in Non-Small-Cell Lung Cancer

Authors: Gkolfinopoulos, Stavros, Mountzios, Giannis

Year: 2019

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2019-0021

Paper Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis.

Yang, Xiaojun, Zeng, Yihong, Tan, Qinquan, Huang, Zhihua, Jia, Jun, Jiang, Guanming · 2022 · Journal of immunology research · DOI

Full title: Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis.

Authors: Yang, Xiaojun, Zeng, Yihong, Tan, Qinquan, Huang, Zhihua, Jia, Jun, Jiang, Guanming

Year: 2022

Venue: Journal of immunology research

DOI: https://doi.org/10.1155/2022/4518898

Paper Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma.

Freimark, Bruce D, Gong, Jian, Ye, Dan, Gray, Michael J, Nguyen, Van, Yin, Shen, Hatch, Michaela M S, Hughes, Christopher C W, Schroit, Alan J, Hutchins, Jeff T, Brekken, Rolf A, Huang, Xianming · 2016 · Cancer immunology research · DOI

Full title: Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma.

Authors: Freimark, Bruce D, Gong, Jian, Ye, Dan, Gray, Michael J, Nguyen, Van, Yin, Shen, Hatch, Michaela M S, Hughes, Christopher C W, Schroit, Alan J, Hutchins, Jeff T, Brekken, Rolf A, Huang, Xianming

Year: 2016

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-15-0250

Paper Successful treatment with intralesional talimogene laherparepvec in two patients with immune checkpoint inhibitor-refractory, advanced-stage melanoma.

Seremet, Teofila, Planken, Simon, Schwarze, Julia K, Jansen, Yanina, Vandeweerd, Laura, van den Begin, Robbe, Tsechelidis, Ioannis, Lienard, Danielle, Del Marmol, Véronique, Neyns, Bart · 2019 · Melanoma research · DOI

Full title: Successful treatment with intralesional talimogene laherparepvec in two patients with immune checkpoint inhibitor-refractory, advanced-stage melanoma.

Authors: Seremet, Teofila, Planken, Simon, Schwarze, Julia K, Jansen, Yanina, Vandeweerd, Laura, van den Begin, Robbe, Tsechelidis, Ioannis, Lienard, Danielle, Del Marmol, Véronique, Neyns, Bart

Year: 2019

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000501

Paper Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer.

R. Ferrara, M. Imbimbo, R. Malouf, S. Paget‐Bailly, F. Calais, C. Marchal, V. Westeel · 2021 · Cochrane Database of Systematic Reviews · DOI

Full title: Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer.

Authors: R. Ferrara, M. Imbimbo, R. Malouf, S. Paget‐Bailly, F. Calais, C. Marchal, V. Westeel

Year: 2021

Venue: Cochrane Database of Systematic Reviews

DOI: https://doi.org/10.1002/14651858.cd013257.pub3

Paper Recent developments with immunotherapy for hepatocellular carcinoma.

Waidmann, Oliver · 2018 · Expert opinion on biological therapy · DOI

Full title: Recent developments with immunotherapy for hepatocellular carcinoma.

Authors: Waidmann, Oliver

Year: 2018

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2018.1499722

Paper Interferon-γ Production by Peripheral Lymphocytes Predicts Survival of Tumor-Bearing Mice Receiving Dual PD-1/CTLA-4 Blockade.

McNamara, Michael J, Hilgart-Martiszus, Ian, Barragan Echenique, Diego M, Linch, Stefanie N, Kasiewicz, Melissa J, Redmond, William L · 2016 · Cancer immunology research · DOI

Full title: Interferon-γ Production by Peripheral Lymphocytes Predicts Survival of Tumor-Bearing Mice Receiving Dual PD-1/CTLA-4 Blockade.

Authors: McNamara, Michael J, Hilgart-Martiszus, Ian, Barragan Echenique, Diego M, Linch, Stefanie N, Kasiewicz, Melissa J, Redmond, William L

Year: 2016

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-16-0022

Paper PD-L1 expression predicts longer disease free survival in high risk head and neck cutaneous squamous cell carcinoma.

Roper, Edward, Lum, Trina, Palme, Carsten E, Ashford, Bruce, Ch'ng, Sydney, Ranson, Marie, Boyer, Michael, Clark, Jonathan, Gupta, Ruta · 2017 · Pathology · DOI

Full title: PD-L1 expression predicts longer disease free survival in high risk head and neck cutaneous squamous cell carcinoma.

Authors: Roper, Edward, Lum, Trina, Palme, Carsten E, Ashford, Bruce, Ch'ng, Sydney, Ranson, Marie, Boyer, Michael, Clark, Jonathan, Gupta, Ruta

Year: 2017

Venue: Pathology

DOI: https://doi.org/10.1016/j.pathol.2017.04.004

Paper [Immune checkpoint (PD-1 and CTIA-4) signal inhibitors for gynecologic oncology; up to date].

Hamanishi, Junzo, Mandai, Masaki, Konishi, Ikuo · 2017 · Nihon rinsho. Japanese journal of clinical medicine

Full title: [Immune checkpoint (PD-1 and CTIA-4) signal inhibitors for gynecologic oncology; up to date].

Authors: Hamanishi, Junzo, Mandai, Masaki, Konishi, Ikuo

Year: 2017

Venue: Nihon rinsho. Japanese journal of clinical medicine

Paper Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists.

Xing, Daniel Tao, Khor, Richard, Gan, Hui, Wada, Morikatsu, Ermongkonchai, Tai, Ng, Sweet Ping · 2021 · Cancers · DOI

Full title: Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists.

Authors: Xing, Daniel Tao, Khor, Richard, Gan, Hui, Wada, Morikatsu, Ermongkonchai, Tai, Ng, Sweet Ping

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13225716

Paper Efficacy and safety of anti-PD-1 and anti-PD-1 combined with anti-CTLA-4 immunotherapy to advanced melanoma: A systematic review and meta-analysis of randomized controlled trials.

Hao, Chunyan, Tian, Jinhui, Liu, Huiling, Li, Fei, Niu, Hongxia, Zhu, Bingdong · 2017 · Medicine · DOI

Full title: Efficacy and safety of anti-PD-1 and anti-PD-1 combined with anti-CTLA-4 immunotherapy to advanced melanoma: A systematic review and meta-analysis of randomized controlled trials.

Authors: Hao, Chunyan, Tian, Jinhui, Liu, Huiling, Li, Fei, Niu, Hongxia, Zhu, Bingdong

Year: 2017

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000007325

Paper The future of immunotherapy in advanced renal cell carcinoma: beyond PD-1/PD-L1 inhibitors.

Nuvola, Giacomo, Mollica, Veronica, Massari, Francesco, Suárez, Cristina · 2023 · Immunotherapy · DOI

Full title: The future of immunotherapy in advanced renal cell carcinoma: beyond PD-1/PD-L1 inhibitors.

Authors: Nuvola, Giacomo, Mollica, Veronica, Massari, Francesco, Suárez, Cristina

Year: 2023

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2023-0218

Paper Risk of Ophthalmic Adverse Events in Patients Treated with Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-analysis.

Hou, Yan-Li, Wang, Di-Ya, Hu, Jie-Xuan, Tian, Ru-Yue, Wang, Wei, Su, Qiang, Li, Hongyang, Wang, Yan-Ling · 2022 · Ocular immunology and inflammation · DOI

Full title: Risk of Ophthalmic Adverse Events in Patients Treated with Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-analysis.

Authors: Hou, Yan-Li, Wang, Di-Ya, Hu, Jie-Xuan, Tian, Ru-Yue, Wang, Wei, Su, Qiang, Li, Hongyang, Wang, Yan-Ling

Year: 2022

Venue: Ocular immunology and inflammation

DOI: https://doi.org/10.1080/09273948.2021.1890133

Paper Abscopal effects observed in cancer radiation therapy and oncolytic virotherapy: an overview.

Romano, G, Marino, I R · 2019 · Drugs of today (Barcelona, Spain : 1998) · DOI

Full title: Abscopal effects observed in cancer radiation therapy and oncolytic virotherapy: an overview.

Authors: Romano, G, Marino, I R

Year: 2019

Venue: Drugs of today (Barcelona, Spain : 1998)

DOI: https://doi.org/10.1358/dot.2019.55.2.2903217

Paper Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy.

Chen, Hongwei, Luan, Xin, Paholak, Hayley J, Burnett, Joseph P, Stevers, Nicholas O, Sansanaphongpricha, Kanokwan, He, Miao, Chang, Alfred E, Li, Qiao, Sun, Duxin · 2020 · Nanomedicine (London, England) · DOI

Full title: Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy.

Authors: Chen, Hongwei, Luan, Xin, Paholak, Hayley J, Burnett, Joseph P, Stevers, Nicholas O, Sansanaphongpricha, Kanokwan, He, Miao, Chang, Alfred E, Li, Qiao, Sun, Duxin

Year: 2020

Venue: Nanomedicine (London, England)

DOI: https://doi.org/10.2217/nnm-2019-0190

Paper Correlation between PD-L1 expression and outcome of NSCLC patients treated with anti-PD-1/PD-L1 agents: A meta-analysis.

Abdel-Rahman, Omar · 2016 · Critical reviews in oncology/hematology · DOI

Full title: Correlation between PD-L1 expression and outcome of NSCLC patients treated with anti-PD-1/PD-L1 agents: A meta-analysis.

Authors: Abdel-Rahman, Omar

Year: 2016

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2016.03.007

Paper Tumor Mutational Burden, Toxicity, and Response of Immune Checkpoint Inhibitors Targeting PD(L)1, CTLA-4, and Combination: A Meta-regression Analysis.

Osipov, Arsen, Lim, Su Jin, Popovic, Aleksandra, Azad, Nilofer S, Laheru, Daniel A, Zheng, Lei, Jaffee, Elizabeth M, Wang, Hao, Yarchoan, Mark · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Tumor Mutational Burden, Toxicity, and Response of Immune Checkpoint Inhibitors Targeting PD(L)1, CTLA-4, and Combination: A Meta-regression Analysis.

Authors: Osipov, Arsen, Lim, Su Jin, Popovic, Aleksandra, Azad, Nilofer S, Laheru, Daniel A, Zheng, Lei, Jaffee, Elizabeth M, Wang, Hao, Yarchoan, Mark

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-0458

Paper Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.

Kim, Wonwoo, Kim, Hyunkyung, Jang, Won Il, Kim, Mi Sook, Bae, Sun Hyun · 2025 · Current issues in molecular biology · DOI

Full title: Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.

Authors: Kim, Wonwoo, Kim, Hyunkyung, Jang, Won Il, Kim, Mi Sook, Bae, Sun Hyun

Year: 2025

Venue: Current issues in molecular biology

DOI: https://doi.org/10.3390/cimb48010020

Paper Immune privilege: failure of immunotherapy in controlling metastatic cutaneous melanoma to the eye.

Sia, David I T, Thaung, Caroline, O'Hanlon-Brown, Ciara, Cohen, Victoria M L, Sagoo, Mandeep S · 2018 · Melanoma research · DOI

Full title: Immune privilege: failure of immunotherapy in controlling metastatic cutaneous melanoma to the eye.

Authors: Sia, David I T, Thaung, Caroline, O'Hanlon-Brown, Ciara, Cohen, Victoria M L, Sagoo, Mandeep S

Year: 2018

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000443

Paper Immunotherapy of head and neck squamous cell carcinoma (HNSCC). Immune checkpoint blockade.

Przybylski, Krzysztof, Majchrzak, Ewa, Weselik, Liucija, Golusiński, Wojciech · 2018 · Otolaryngologia polska = The Polish otolaryngology · DOI

Full title: Immunotherapy of head and neck squamous cell carcinoma (HNSCC). Immune checkpoint blockade.

Authors: Przybylski, Krzysztof, Majchrzak, Ewa, Weselik, Liucija, Golusiński, Wojciech

Year: 2018

Venue: Otolaryngologia polska = The Polish otolaryngology

DOI: https://doi.org/10.5604/01.3001.0012.4367

Paper The influence of radiation in the context of developing combination immunotherapies in cancer

Honeychurch, Jamie, Illidge, Tim · 2017 · Therapeutic Advances in Vaccines and Immunotherapy · DOI

Full title: The influence of radiation in the context of developing combination immunotherapies in cancer

Authors: Honeychurch, Jamie, Illidge, Tim

Year: 2017

Venue: Therapeutic Advances in Vaccines and Immunotherapy

DOI: https://doi.org/10.1177/2051013617750561

Paper Corticosteroid premedication on anti-tumor effect of immune checkpoint blockade in murine hepatocellular carcinoma models.

Shen, Ying-Chun, Chang, Nai-Wen, Yeh, Ching-Ping, Lin, Wan-Ying, Wei, Ming-Feng, Ou, Da-Liang, Hsu, Chia-Lang, Cheng, Ann-Lii · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Corticosteroid premedication on anti-tumor effect of immune checkpoint blockade in murine hepatocellular carcinoma models.

Authors: Shen, Ying-Chun, Chang, Nai-Wen, Yeh, Ching-Ping, Lin, Wan-Ying, Wei, Ming-Feng, Ou, Da-Liang, Hsu, Chia-Lang, Cheng, Ann-Lii

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-009704

Paper CTIM-29. TOXICITY PROFILE OF DUAL IMMUNE CHECKPOINT BLOCKADE IN MELANOMA BRAIN METASTASES: A META-ANALYSIS OF GRADE ≥3 AND IMMUNE-RELATED ADVERSE EVENTS

Sarfraz, Zouina, Ganiyani, Mohammad Arfat, Mustafayev, Fatma Nihan Akkoç, Mustafayev, Khalis, Odia, Yazmín, Kotecha, Rupesh, Mansouri, Alireza, Ahluwalia, Manmeet S. · 2025 · Neuro-Oncology · DOI

Full title: CTIM-29. TOXICITY PROFILE OF DUAL IMMUNE CHECKPOINT BLOCKADE IN MELANOMA BRAIN METASTASES: A META-ANALYSIS OF GRADE ≥3 AND IMMUNE-RELATED ADVERSE EVENTS

Authors: Sarfraz, Zouina, Ganiyani, Mohammad Arfat, Mustafayev, Fatma Nihan Akkoç, Mustafayev, Khalis, Odia, Yazmín, Kotecha, Rupesh, Mansouri, Alireza, Ahluwalia, Manmeet S.

Year: 2025

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noaf201.0486

Paper Targeting CTLA-4 in Cancer: Biological Insights with a Focus on Renal Cell Carcinoma

Juan Wu, Yang Ren, Jun Xie, Dong-sheng Li · 2022 · annals of urologic oncology · DOI

Full title: Targeting CTLA-4 in Cancer: Biological Insights with a Focus on Renal Cell Carcinoma

Authors: Juan Wu, Yang Ren, Jun Xie, Dong-sheng Li

Year: 2022

Venue: annals of urologic oncology

DOI: https://doi.org/10.32948/auo.2022.12.15

Paper Combination of agonist anti-OX40 therapy with CTLA-4 blockade augments anti-tumor effector CD4 and CD8 T cells (P4318)

William L. Redmond, Stefanie N. Linch, Melissa J. Kasiewicz · 2013 · Journal of Immunology · DOI

Full title: Combination of agonist anti-OX40 therapy with CTLA-4 blockade augments anti-tumor effector CD4 and CD8 T cells (P4318)

Authors: William L. Redmond, Stefanie N. Linch, Melissa J. Kasiewicz

Year: 2013

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.190.supp.45.7

Paper New strategies to enhance the efficacy of PD-1/PD-L1 inhibitors in treating microsatellite stable colorectal cancer.

Chen, Yuhan, Tang, Dong · 2025 · Future oncology (London, England) · DOI

Full title: New strategies to enhance the efficacy of PD-1/PD-L1 inhibitors in treating microsatellite stable colorectal cancer.

Authors: Chen, Yuhan, Tang, Dong

Year: 2025

Venue: Future oncology (London, England)

DOI: https://doi.org/10.1080/14796694.2025.2558287

Paper Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model.

Yu, Ping, Steel, Jason C, Zhang, Meili, Morris, John C, Waldmann, Thomas A · 2010 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model.

Authors: Yu, Ping, Steel, Jason C, Zhang, Meili, Morris, John C, Waldmann, Thomas A

Year: 2010

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-10-1966

Paper C-PLAN index as a prognostic factor for patients with previously untreated advanced non-small cell lung cancer who received combination immunotherapy: A multicenter retrospective study.

Sonehara, Kei, Ozawa, Ryota, Hama, Mineyuki, Nozawa, Shuhei, Agatsuma, Toshihiko, Nishie, Kenichi, Kato, Akane, Matsuo, Akemi, Araki, Taisuke, Komatsu, Masamichi, Tateishi, Kazunari, Hanaoka, Masayuki · 2023 · Thoracic cancer · DOI

Full title: C-PLAN index as a prognostic factor for patients with previously untreated advanced non-small cell lung cancer who received combination immunotherapy: A multicenter retrospective study.

Authors: Sonehara, Kei, Ozawa, Ryota, Hama, Mineyuki, Nozawa, Shuhei, Agatsuma, Toshihiko, Nishie, Kenichi, Kato, Akane, Matsuo, Akemi, Araki, Taisuke, Komatsu, Masamichi, Tateishi, Kazunari, Hanaoka, Masayuki

Year: 2023

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.14798

Paper Intratumoral anti-CTLA-4 therapy: enhancing efficacy while avoiding toxicity.

Marabelle, Aurélien, Kohrt, Holbrook, Levy, Ronald · 2013 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Intratumoral anti-CTLA-4 therapy: enhancing efficacy while avoiding toxicity.

Authors: Marabelle, Aurélien, Kohrt, Holbrook, Levy, Ronald

Year: 2013

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-13-1923

Paper Efficacy and Safety of Combination Therapy With Immune Checkpoint Inhibitors and Chemotherapy With Gemcitabine and Nab-Paclitaxel in Pancreatic Cancer: A Systematic Review.

Sohrabi, Hanye, Ghavam, Seyed Mohammad, Azadnajafabad, Sina, Rezaei, Nima · 2026 · Cancer medicine · DOI

Full title: Efficacy and Safety of Combination Therapy With Immune Checkpoint Inhibitors and Chemotherapy With Gemcitabine and Nab-Paclitaxel in Pancreatic Cancer: A Systematic Review.

Authors: Sohrabi, Hanye, Ghavam, Seyed Mohammad, Azadnajafabad, Sina, Rezaei, Nima

Year: 2026

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.71637

Paper An Artificial Antigen-Presenting Cell Delivering 11 Immune Molecules Expands Tumor Antigen-Specific CTLs in Ex Vivo and In Vivo Murine Melanoma Models.

Zhang, Lei, Song, Shilong, Jin, Xiaoxiao, Wan, Xin, Shahzad, Khawar Ali, Pei, Weiya, Zhao, Chen, Shen, Chuanlai · 2019 · Cancer immunology research · DOI

Full title: An Artificial Antigen-Presenting Cell Delivering 11 Immune Molecules Expands Tumor Antigen-Specific CTLs in Ex Vivo and In Vivo Murine Melanoma Models.

Authors: Zhang, Lei, Song, Shilong, Jin, Xiaoxiao, Wan, Xin, Shahzad, Khawar Ali, Pei, Weiya, Zhao, Chen, Shen, Chuanlai

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0881

Paper MMAP-07 IMPACT OF SINGLE AND DUAL IMMUNE CHECKPOINT BLOCKADE ON RISK OF RADIATION NECROSIS AMONG PATIENTS WITH BRAIN METASTASES TREATED WITH STEREOTACTIC RADIOSURGERY

E. Vaios, R. Shenker, P. Hendrickson, R. D’Anna, D. Niedzwiecki, D. Carpenter, Warren Floyd, Sebastian F. Winter, J. Dietrich, S. Floyd, J. Kirkpatrick, T. Mullikin, K. Allen, A. Salama, J. Clarke, Z. Reitman · 2022 · Neuro-Oncology Advances · DOI

Full title: MMAP-07 IMPACT OF SINGLE AND DUAL IMMUNE CHECKPOINT BLOCKADE ON RISK OF RADIATION NECROSIS AMONG PATIENTS WITH BRAIN METASTASES TREATED WITH STEREOTACTIC RADIOSURGERY

Authors: E. Vaios, R. Shenker, P. Hendrickson, R. D’Anna, D. Niedzwiecki, D. Carpenter, Warren Floyd, Sebastian F. Winter, J. Dietrich, S. Floyd, J. Kirkpatrick, T. Mullikin, K. Allen, A. Salama, J. Clarke, Z. Reitman

Year: 2022

Venue: Neuro-Oncology Advances

DOI: https://doi.org/10.1093/noajnl/vdac078.063

Paper Occurrence of type 1 and type 2 diabetes in patients treated with immunotherapy (anti-PD-1 and/or anti-CTLA-4) for metastatic melanoma: a retrospective study.

Gauci, Marie-Léa, Boudou, Philippe, Baroudjian, Barouyr, Vidal-Trecan, Tiphaine, Da Meda, Laetitia, Madelaine-Chambrin, Isabelle, Basset-Seguin, Nicole, Bagot, Martine, Pages, Cécile, Mourah, Samia, Resche-Rigon, Matthieu, Pinel, Sylvine, Sassier, Marion, Rouby, Franck, Eftekhari, Pirayeh, Lebbé, Céleste, Gautier, Jean-François · 2018 · Cancer immunology, immunotherapy : CII · DOI

Full title: Occurrence of type 1 and type 2 diabetes in patients treated with immunotherapy (anti-PD-1 and/or anti-CTLA-4) for metastatic melanoma: a retrospective study.

Authors: Gauci, Marie-Léa, Boudou, Philippe, Baroudjian, Barouyr, Vidal-Trecan, Tiphaine, Da Meda, Laetitia, Madelaine-Chambrin, Isabelle, Basset-Seguin, Nicole, Bagot, Martine, Pages, Cécile, Mourah, Samia, Resche-Rigon, Matthieu, Pinel, Sylvine, Sassier, Marion, Rouby, Franck, Eftekhari, Pirayeh, Lebbé, Céleste, Gautier, Jean-François

Year: 2018

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-018-2178-0

Paper Durable Marked Response of Unresectable Esophageal Squamous Cell Carcinoma After Radiotherapy Alone Followed by Combination Immunotherapy.

Watanabe, Yasuhiro, Miyamoto, Shin Ichi, Asano, Yoichi, Yaku, Hiroaki, Ueki, Kazuhito, Araki, Norio, Ueo, Taro · 2026 · Case reports in oncological medicine · DOI

Full title: Durable Marked Response of Unresectable Esophageal Squamous Cell Carcinoma After Radiotherapy Alone Followed by Combination Immunotherapy.

Authors: Watanabe, Yasuhiro, Miyamoto, Shin Ichi, Asano, Yoichi, Yaku, Hiroaki, Ueki, Kazuhito, Araki, Norio, Ueo, Taro

Year: 2026

Venue: Case reports in oncological medicine

DOI: https://doi.org/10.1155/crom/3970015

Paper A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab.

Adusumilli, Prasad S, Zauderer, Marjorie G, Rivière, Isabelle, Solomon, Stephen B, Rusch, Valerie W, O'Cearbhaill, Roisin E, Zhu, Amy, Cheema, Waseem, Chintala, Navin K, Halton, Elizabeth, Pineda, John, Perez-Johnston, Rocio, Tan, Kay See, Daly, Bobby, Araujo Filho, Jose A, Ngai, Daniel, McGee, Erin, Vincent, Alain, Diamonte, Claudia, Sauter, Jennifer L, Modi, Shanu, Sikder, Devanjan, Senechal, Brigitte, Wang, Xiuyan, Travis, William D, Gönen, Mithat, Rudin, Charles M, Brentjens, Renier J, Jones, David R, Sadelain, Michel · 2021 · Cancer discovery · DOI

Full title: A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab.

Authors: Adusumilli, Prasad S, Zauderer, Marjorie G, Rivière, Isabelle, Solomon, Stephen B, Rusch, Valerie W, O'Cearbhaill, Roisin E, Zhu, Amy, Cheema, Waseem, Chintala, Navin K, Halton, Elizabeth, Pineda, John, Perez-Johnston, Rocio, Tan, Kay See, Daly, Bobby, Araujo Filho, Jose A, Ngai, Daniel, McGee, Erin, Vincent, Alain, Diamonte, Claudia, Sauter, Jennifer L, Modi, Shanu, Sikder, Devanjan, Senechal, Brigitte, Wang, Xiuyan, Travis, William D, Gönen, Mithat, Rudin, Charles M, Brentjens, Renier J, Jones, David R, Sadelain, Michel

Year: 2021

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-21-0407

Paper Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model.

Llopiz, Diana, Ruiz, Marta, Villanueva, Lorea, Iglesias, Tamara, Silva, Leyre, Egea, Josune, Lasarte, Juan J, Pivette, Perrine, Trochon-Joseph, Véronique, Vasseur, Bérangère, Dixon, Graham, Sangro, Bruno, Sarobe, Pablo · 2019 · Cancer immunology, immunotherapy : CII · DOI

Full title: Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model.

Authors: Llopiz, Diana, Ruiz, Marta, Villanueva, Lorea, Iglesias, Tamara, Silva, Leyre, Egea, Josune, Lasarte, Juan J, Pivette, Perrine, Trochon-Joseph, Véronique, Vasseur, Bérangère, Dixon, Graham, Sangro, Bruno, Sarobe, Pablo

Year: 2019

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-018-2283-0

Paper Anti-CTLA-4 antibody self-presented dendritic cell nanovesicles boost the immunotherapy of hepatocellular carcinoma after microwave ablation.

Li, Tan, Li, Bo, Lin, Liteng, Chen, Gengjia, Wang, Xiaobin, Chen, Ye, Huang, Wensou, Cai, Mingyue, Shuai, Xintao, Zhu, Kangshun · 2024 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Anti-CTLA-4 antibody self-presented dendritic cell nanovesicles boost the immunotherapy of hepatocellular carcinoma after microwave ablation.

Authors: Li, Tan, Li, Bo, Lin, Liteng, Chen, Gengjia, Wang, Xiaobin, Chen, Ye, Huang, Wensou, Cai, Mingyue, Shuai, Xintao, Zhu, Kangshun

Year: 2024

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2024.10.069

Paper Skin Reactions to Immune Checkpoint Inhibitors.

Patel, Anisha B, Pacha, Omar · 2021 · Advances in experimental medicine and biology · DOI

Full title: Skin Reactions to Immune Checkpoint Inhibitors.

Authors: Patel, Anisha B, Pacha, Omar

Year: 2021

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-030-79308-1_11

Paper First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melanoma

Turajlic, Samra, Gore, Martin, Larkin, James · 2018 · Annals of Oncology · DOI

Full title: First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melanoma

Authors: Turajlic, Samra, Gore, Martin, Larkin, James

Year: 2018

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdy020

Paper PD-1/PD-L1 immune checkpoint blockade-based combinational treatment: Immunotherapeutic amplification strategies against colorectal cancer.

Chen, Yuxiang, Liu, Chi, Zhu, Shaomi, Liang, Xin, Zhang, Qinxiu, Luo, Xiaohong, Yuan, Lan, Song, Linjiang · 2021 · International immunopharmacology · DOI

Full title: PD-1/PD-L1 immune checkpoint blockade-based combinational treatment: Immunotherapeutic amplification strategies against colorectal cancer.

Authors: Chen, Yuxiang, Liu, Chi, Zhu, Shaomi, Liang, Xin, Zhang, Qinxiu, Luo, Xiaohong, Yuan, Lan, Song, Linjiang

Year: 2021

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2021.107607

Paper [Combination Therapy of Immune Checkpoint Inhibitors].

Kitano, Shigehisa · 2017 · Gan to kagaku ryoho. Cancer & chemotherapy

Full title: [Combination Therapy of Immune Checkpoint Inhibitors].

Authors: Kitano, Shigehisa

Year: 2017

Venue: Gan to kagaku ryoho. Cancer & chemotherapy

Paper Cardiotoxicity associated with immune checkpoint inhibitor therapy: a meta-analysis.

Rubio-Infante, Nestor, Ramírez-Flores, Yoel A, Castillo, Elena C, Lozano, Omar, García-Rivas, Gerardo, Torre-Amione, Guillermo · 2021 · European journal of heart failure · DOI

Full title: Cardiotoxicity associated with immune checkpoint inhibitor therapy: a meta-analysis.

Authors: Rubio-Infante, Nestor, Ramírez-Flores, Yoel A, Castillo, Elena C, Lozano, Omar, García-Rivas, Gerardo, Torre-Amione, Guillermo

Year: 2021

Venue: European journal of heart failure

DOI: https://doi.org/10.1002/ejhf.2289

Paper Combined immunotherapy for metastatic triple-negative breast cancer based on PD-1/PD-L1 immune checkpoint blocking.

He, Rui, Yuan, Xing, Chen, Zeran, Zheng, Yongfeng · 2022 · International immunopharmacology · DOI

Full title: Combined immunotherapy for metastatic triple-negative breast cancer based on PD-1/PD-L1 immune checkpoint blocking.

Authors: He, Rui, Yuan, Xing, Chen, Zeran, Zheng, Yongfeng

Year: 2022

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2022.109444

Paper Neurological adverse events associated with immune checkpoint inhibitors: Review of the literature.

Cuzzubbo, S, Javeri, F, Tissier, M, Roumi, A, Barlog, C, Doridam, J, Lebbe, C, Belin, C, Ursu, R, Carpentier, A F · 2017 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Neurological adverse events associated with immune checkpoint inhibitors: Review of the literature.

Authors: Cuzzubbo, S, Javeri, F, Tissier, M, Roumi, A, Barlog, C, Doridam, J, Lebbe, C, Belin, C, Ursu, R, Carpentier, A F

Year: 2017

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2016.12.001

Paper Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model.

Asby, Sarah C, Thompson, Lauren E, Goedken, Michael, Lucia, Scott M, Dominguez, Adrian T, Kar, Adwitiya, Pitts, Todd M, Kiseljak-Vassiliades, Katja, Lang, Julie, Aleksunes, Lauren M, Joy, Melanie S · 2025 · Kidney international · DOI

Full title: Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model.

Authors: Asby, Sarah C, Thompson, Lauren E, Goedken, Michael, Lucia, Scott M, Dominguez, Adrian T, Kar, Adwitiya, Pitts, Todd M, Kiseljak-Vassiliades, Katja, Lang, Julie, Aleksunes, Lauren M, Joy, Melanie S

Year: 2025

Venue: Kidney international

DOI: https://doi.org/10.1016/j.kint.2025.01.021

Paper Pulmonary metastasectomy in the era of targeted therapy and immunotherapy.

Bong, Christopher Y, Smithers, B Mark, Chua, Terence C · 2021 · Journal of thoracic disease · DOI

Full title: Pulmonary metastasectomy in the era of targeted therapy and immunotherapy.

Authors: Bong, Christopher Y, Smithers, B Mark, Chua, Terence C

Year: 2021

Venue: Journal of thoracic disease

DOI: https://doi.org/10.21037/jtd.2020.03.120

Paper New therapies for brain metastases: an update.

Porte, Marie, Massard, Christophe · 2025 · Current opinion in oncology · DOI

Full title: New therapies for brain metastases: an update.

Authors: Porte, Marie, Massard, Christophe

Year: 2025

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000001195

Paper Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4+Foxp3- Cell-Mediated Modulation of CD103+ Dendritic Cells.

Beavis, Paul A, Henderson, Melissa A, Giuffrida, Lauren, Davenport, Alexander J, Petley, Emma V, House, Imran G, Lai, Junyun, Sek, Kevin, Milenkovski, Nicole, John, Liza B, Mardiana, Sherly, Slaney, Clare Y, Trapani, Joseph A, Loi, Sherene, Kershaw, Michael H, Haynes, Nicole M, Darcy, Phillip K · 2018 · Cancer immunology research · DOI

Full title: Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4+Foxp3- Cell-Mediated Modulation of CD103+ Dendritic Cells.

Authors: Beavis, Paul A, Henderson, Melissa A, Giuffrida, Lauren, Davenport, Alexander J, Petley, Emma V, House, Imran G, Lai, Junyun, Sek, Kevin, Milenkovski, Nicole, John, Liza B, Mardiana, Sherly, Slaney, Clare Y, Trapani, Joseph A, Loi, Sherene, Kershaw, Michael H, Haynes, Nicole M, Darcy, Phillip K

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0291

Paper IMMUNOTHERAPY TREATMENT AGAINST CERVICAL CANCER.

Jiménez-Lima, Roberto, Arango-Bravo, Eder, Galicia-Carmona, Tatiana, Lino-Silva, Leonardo S, Trejo-Durán, Guadalupe E, Alvarado-Silva, Cristina, Castañeda-Renderos, Omar H, Vanoye-Carlo, Elva G, Torre, Celia Flores-de la, Dueñas-González, Alfonso, Cetina-Pérez, Lucely · 2020 · Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion · DOI

Full title: IMMUNOTHERAPY TREATMENT AGAINST CERVICAL CANCER.

Authors: Jiménez-Lima, Roberto, Arango-Bravo, Eder, Galicia-Carmona, Tatiana, Lino-Silva, Leonardo S, Trejo-Durán, Guadalupe E, Alvarado-Silva, Cristina, Castañeda-Renderos, Omar H, Vanoye-Carlo, Elva G, Torre, Celia Flores-de la, Dueñas-González, Alfonso, Cetina-Pérez, Lucely

Year: 2020

Venue: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

DOI: https://doi.org/10.24875/RIC.20000060

Paper New-onset toxicity with programmed death-1 inhibitor rechallenge.

Ludlow, Steven P, Andrews, Stephanie, Pasikhova, Yanina, Hill, Eboné · 2016 · Melanoma research · DOI

Full title: New-onset toxicity with programmed death-1 inhibitor rechallenge.

Authors: Ludlow, Steven P, Andrews, Stephanie, Pasikhova, Yanina, Hill, Eboné

Year: 2016

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000259

Paper Clinical benefit of neoadjuvant anti-PD-1/PD-L1 utilization among different tumors.

Li, Zhiyang, Wu, Xin, Zhao, Yanjie, Xiao, Yinan, Zhao, Yunuo, Zhang, Ting, Li, Hui, Sha, Fushen, Wang, Yating, Deng, Lei, Ma, Xuelei · 2021 · MedComm · DOI

Full title: Clinical benefit of neoadjuvant anti-PD-1/PD-L1 utilization among different tumors.

Authors: Li, Zhiyang, Wu, Xin, Zhao, Yanjie, Xiao, Yinan, Zhao, Yunuo, Zhang, Ting, Li, Hui, Sha, Fushen, Wang, Yating, Deng, Lei, Ma, Xuelei

Year: 2021

Venue: MedComm

DOI: https://doi.org/10.1002/mco2.61

Paper Cancer immunology - development of novel anti-cancer therapies.

Rothschild, Sacha I, Thommen, Daniela S, Moersig, Wolfgang, Müller, Philipp, Zippelius, Alfred · 2015 · Swiss medical weekly · DOI

Full title: Cancer immunology - development of novel anti-cancer therapies.

Authors: Rothschild, Sacha I, Thommen, Daniela S, Moersig, Wolfgang, Müller, Philipp, Zippelius, Alfred

Year: 2015

Venue: Swiss medical weekly

DOI: https://doi.org/10.4414/smw.2015.14066

Paper Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy.

Ciardiello, Davide, Vitiello, Pietro Paolo, Cardone, Claudia, Martini, Giulia, Troiani, Teresa, Martinelli, Erika, Ciardiello, Fortunato · 2019 · Cancer treatment reviews · DOI

Full title: Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy.

Authors: Ciardiello, Davide, Vitiello, Pietro Paolo, Cardone, Claudia, Martini, Giulia, Troiani, Teresa, Martinelli, Erika, Ciardiello, Fortunato

Year: 2019

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2019.04.003

Paper Impact of adding immune checkpoint inhibitors to standard therapies in non-small cell lung cancer: A systematic review of efficacy outcomes.

Correia, Ana Pinto, Marques, Adriana, Sepodes, Bruno, Torre, Carla, Rocha, João · 2026 · Critical reviews in oncology/hematology · DOI

Full title: Impact of adding immune checkpoint inhibitors to standard therapies in non-small cell lung cancer: A systematic review of efficacy outcomes.

Authors: Correia, Ana Pinto, Marques, Adriana, Sepodes, Bruno, Torre, Carla, Rocha, João

Year: 2026

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2025.105098

Paper Comprehensive molecular profiling of metastatic melanoma to predict response to monotherapy and combination immunotherapy.

Silva, Ines Esteves Domingues Pires Da, Menzies, Alexander M., Newell, Felicity, Wilmott, James S., Carlino, Matteo S., Ferguson, Peter M., Edwards, Jarem, Spillane, Andrew J., Shannon, Kerwin F., Saw, Robyn P.M., Thompson, John F., Rizos, Helen, Mann, Graham J., Johansson, Peter A., Hayward, Nicholas K., Scolyer, Richard A., Waddell, Nicola, Long, Georgina V. · 2019 · Journal of Clinical Oncology · DOI

Full title: Comprehensive molecular profiling of metastatic melanoma to predict response to monotherapy and combination immunotherapy.

Authors: Silva, Ines Esteves Domingues Pires Da, Menzies, Alexander M., Newell, Felicity, Wilmott, James S., Carlino, Matteo S., Ferguson, Peter M., Edwards, Jarem, Spillane, Andrew J., Shannon, Kerwin F., Saw, Robyn P.M., Thompson, John F., Rizos, Helen, Mann, Graham J., Johansson, Peter A., Hayward, Nicholas K., Scolyer, Richard A., Waddell, Nicola, Long, Georgina V.

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.9511

Paper Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer

Dudzinski, Stephanie O., Cameron, Brent D., Wang, Jian, Rathmell, Jeffrey C., Giorgio, Todd D., Kirschner, Austin N. · 2019 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer

Authors: Dudzinski, Stephanie O., Cameron, Brent D., Wang, Jian, Rathmell, Jeffrey C., Giorgio, Todd D., Kirschner, Austin N.

Year: 2019

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-019-0704-z

Paper PD-1 and TIGIT coexpressing CD8 + CD103 + tissue-resident memory cells in endometrial cancer as potential targets for immunotherapy.

Jiang, Fang, Mao, Mingyi, Jiang, Shiyang, Jiao, Yuhao, Cao, Dongyan, Xiang, Yang · 2024 · International immunopharmacology · DOI

Full title: PD-1 and TIGIT coexpressing CD8 + CD103 + tissue-resident memory cells in endometrial cancer as potential targets for immunotherapy.

Authors: Jiang, Fang, Mao, Mingyi, Jiang, Shiyang, Jiao, Yuhao, Cao, Dongyan, Xiang, Yang

Year: 2024

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.111381

Paper Predictive Factors Associated with Long-Term Response to Combination Immunotherapy in Patients with Untreated Advanced Non-Small-Cell Lung Cancer: A Multicenter Retrospective Study.

Full title: Predictive Factors Associated with Long-Term Response to Combination Immunotherapy in Patients with Untreated Advanced Non-Small-Cell Lung Cancer: A Multicenter Retrospective Study.

Year: 2023

Venue: Oncology

DOI: https://doi.org/10.1159/000531324

Paper Blockade of Programmed Death Ligand 1 Enhances the Therapeutic Efficacy of Combination Immunotherapy against Melanoma

S. Pilon-Thomas, A. Mackay, N. Vohra, J. Mulé · 2010 · Journal of Immunology · DOI

Full title: Blockade of Programmed Death Ligand 1 Enhances the Therapeutic Efficacy of Combination Immunotherapy against Melanoma

Authors: S. Pilon-Thomas, A. Mackay, N. Vohra, J. Mulé

Year: 2010

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.0904114

Paper Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Full title: Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

Year: 2018

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-18-1038

Paper Plinabulin, a novel small molecule clinical stage IO agent with anti-cancer activity, to prevent chemo-induced neutropenia and immune related AEs.

Mohanlal, Ramon, Lloyd, Ken, Huang, Lan · 2018 · Journal of Clinical Oncology · DOI

Full title: Plinabulin, a novel small molecule clinical stage IO agent with anti-cancer activity, to prevent chemo-induced neutropenia and immune related AEs.

Authors: Mohanlal, Ramon, Lloyd, Ken, Huang, Lan

Year: 2018

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2018.36.5_suppl.126

Paper Quick efficacy seeking trial (QuEST1): a novel combination immunotherapy study designed for rapid clinical signal assessment metastatic castration-resistant prostate cancer.

Redman, Jason M, Steinberg, Seth M, Gulley, James L · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Quick efficacy seeking trial (QuEST1): a novel combination immunotherapy study designed for rapid clinical signal assessment metastatic castration-resistant prostate cancer.

Authors: Redman, Jason M, Steinberg, Seth M, Gulley, James L

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0409-8

Paper SHISA3 Reprograms Tumor‐Associated Macrophages Toward an Antitumoral Phenotype and Enhances Cancer Immunotherapy

Zhang, Shimeng, Yu, Bingbing, Sheng, Chunjie, Yao, Chen, Liu, Yang, Wang, Jing, Zeng, Qi, Mao, Yizhi, Bei, Jin‐Xin, Zhu, Bin, Chen, Shuai · 2024 · Advanced Science · DOI

Full title: SHISA3 Reprograms Tumor‐Associated Macrophages Toward an Antitumoral Phenotype and Enhances Cancer Immunotherapy

Authors: Zhang, Shimeng, Yu, Bingbing, Sheng, Chunjie, Yao, Chen, Liu, Yang, Wang, Jing, Zeng, Qi, Mao, Yizhi, Bei, Jin‐Xin, Zhu, Bin, Chen, Shuai

Year: 2024

Venue: Advanced Science

DOI: https://doi.org/10.1002/advs.202403019

Paper Parameters of Tumor Microenvironment Determine Effectiveness of Anti-PD-1/PD-L1 Therapy.

Tashireva, Liubov A, Muravyova, Dariya T, Popova, Natalya O, Goldberg, Victor E, Vtorushin, Sergey V, Perelmuter, Vladimir M · 2021 · Biochemistry. Biokhimiia · DOI

Full title: Parameters of Tumor Microenvironment Determine Effectiveness of Anti-PD-1/PD-L1 Therapy.

Authors: Tashireva, Liubov A, Muravyova, Dariya T, Popova, Natalya O, Goldberg, Victor E, Vtorushin, Sergey V, Perelmuter, Vladimir M

Year: 2021

Venue: Biochemistry. Biokhimiia

DOI: https://doi.org/10.1134/S0006297921110092

Paper RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.

van Dam, Peter A, Verhoeven, Yannick, Trinh, Xuan B, Wouters, An, Lardon, Filip, Prenen, Hans, Smits, Evelien, Baldewijns, Marcella, Lammens, Martin · 2019 · Critical reviews in oncology/hematology · DOI

Full title: RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.

Authors: van Dam, Peter A, Verhoeven, Yannick, Trinh, Xuan B, Wouters, An, Lardon, Filip, Prenen, Hans, Smits, Evelien, Baldewijns, Marcella, Lammens, Martin

Year: 2019

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2018.10.011

Paper Histopathologic Characterization of Myocarditis Associated With Immune Checkpoint Inhibitor Therapy.

Sobol, Irina, Chen, Carol L, Mahmood, Syed S, Borczuk, Alain C · 2020 · Archives of pathology & laboratory medicine · DOI

Full title: Histopathologic Characterization of Myocarditis Associated With Immune Checkpoint Inhibitor Therapy.

Authors: Sobol, Irina, Chen, Carol L, Mahmood, Syed S, Borczuk, Alain C

Year: 2020

Venue: Archives of pathology & laboratory medicine

DOI: https://doi.org/10.5858/arpa.2019-0447-OA

Paper Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma.

Läubli, Heinz, Balmelli, Cathrin, Bossard, Matthias, Pfister, Otmar, Glatz, Kathrin, Zippelius, Alfred · 2015 · Journal for immunotherapy of cancer · DOI

Full title: Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma.

Authors: Läubli, Heinz, Balmelli, Cathrin, Bossard, Matthias, Pfister, Otmar, Glatz, Kathrin, Zippelius, Alfred

Year: 2015

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-015-0057-1

Paper Immune checkpoint blockade for advanced non-small cell lung cancer: challenging clinical scenarios

Tay, Rebecca, Prelaj, Arsela, Califano, Raffaele · 2018 · Journal of Thoracic Disease · DOI

Full title: Immune checkpoint blockade for advanced non-small cell lung cancer: challenging clinical scenarios

Authors: Tay, Rebecca, Prelaj, Arsela, Califano, Raffaele

Year: 2018

Venue: Journal of Thoracic Disease

DOI: https://doi.org/10.21037/jtd.2018.01.80

Paper Immune checkpoint inhibitor-induced myasthenia gravis, myocarditis, and myositis: A case report.

Basnet, Arjun, Sharma, Nava Raj, Gautam, Sudarshan, Lamichhane, Saral, Kansakar, Sajog, Tiwari, Kripa, Pokhrel, Madalasa, Singh, Sehajpreet · 2024 · Clinical case reports · DOI

Full title: Immune checkpoint inhibitor-induced myasthenia gravis, myocarditis, and myositis: A case report.

Authors: Basnet, Arjun, Sharma, Nava Raj, Gautam, Sudarshan, Lamichhane, Saral, Kansakar, Sajog, Tiwari, Kripa, Pokhrel, Madalasa, Singh, Sehajpreet

Year: 2024

Venue: Clinical case reports

DOI: https://doi.org/10.1002/ccr3.8968

Paper Ipilimumab (Yervoy) and the TGN1412 catastrophe.

Bakacs, Tibor, Mehrishi, Jitendra N, Moss, Ralph W · 2012 · Immunobiology · DOI

Full title: Ipilimumab (Yervoy) and the TGN1412 catastrophe.

Authors: Bakacs, Tibor, Mehrishi, Jitendra N, Moss, Ralph W

Year: 2012

Venue: Immunobiology

DOI: https://doi.org/10.1016/j.imbio.2011.07.005

Paper IL2/Anti-IL2 Complex Combined with CTLA-4, But Not PD-1, Blockade Rescues Antitumor NK Cell Function by Regulatory T-cell Modulation.

Caudana, Pamela, Núñez, Nicolas Gonzalo, De La Rochere, Philippe, Pinto, Anaïs, Denizeau, Jordan, Alonso, Ruby, Niborski, Leticia Laura, Lantz, Olivier, Sedlik, Christine, Piaggio, Eliane · 2019 · Cancer immunology research · DOI

Full title: IL2/Anti-IL2 Complex Combined with CTLA-4, But Not PD-1, Blockade Rescues Antitumor NK Cell Function by Regulatory T-cell Modulation.

Authors: Caudana, Pamela, Núñez, Nicolas Gonzalo, De La Rochere, Philippe, Pinto, Anaïs, Denizeau, Jordan, Alonso, Ruby, Niborski, Leticia Laura, Lantz, Olivier, Sedlik, Christine, Piaggio, Eliane

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0697

Paper The Risk of Immune-Related Thyroid Dysfunction Induced by PD-1/PD-L1 Inhibitors in Cancer Patients: An Updated Systematic Review and Meta-Analysis.

Tian, Yuan, Li, Ran, Liu, Yan, Li, Meng, Song, Yuxiao, Zheng, Yan, Gao, Aiqin, Wen, Qing, Su, Guohai, Sun, Yuping · 2021 · Frontiers in oncology · DOI

Full title: The Risk of Immune-Related Thyroid Dysfunction Induced by PD-1/PD-L1 Inhibitors in Cancer Patients: An Updated Systematic Review and Meta-Analysis.

Authors: Tian, Yuan, Li, Ran, Liu, Yan, Li, Meng, Song, Yuxiao, Zheng, Yan, Gao, Aiqin, Wen, Qing, Su, Guohai, Sun, Yuping

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.667650

Paper [Importance of the Immune System and Immunotherapeutic Options in Malignant Melanoma].

Krajsová, I · 2015 · Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti · DOI

Full title: [Importance of the Immune System and Immunotherapeutic Options in Malignant Melanoma].

Authors: Krajsová, I

Year: 2015

Venue: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

DOI: https://doi.org/10.14735/amko20154s56

Paper Systemic Therapy for Hepatocellular Carcinoma: 2017 Update.

Kudo, Masatoshi · 2017 · Oncology · DOI

Full title: Systemic Therapy for Hepatocellular Carcinoma: 2017 Update.

Authors: Kudo, Masatoshi

Year: 2017

Venue: Oncology

DOI: https://doi.org/10.1159/000481244

Paper Adverse events of targeted anticancer therapies: what radiologists need to know.

López Sala, P, Alberdi Aldasoro, N, Unzué García-Falces, G · 2020 · Radiologia · DOI

Full title: Adverse events of targeted anticancer therapies: what radiologists need to know.

Authors: López Sala, P, Alberdi Aldasoro, N, Unzué García-Falces, G

Year: 2020

Venue: Radiologia

DOI: https://doi.org/10.1016/j.rx.2019.12.008

Paper Efficiency and toxicity of nab-paclitaxel and camrelizumab in the second or above line treatment of advanced non-small cell lung cancer: a retrospective cohort study.

Yin, Chen, Zou, Guo-Rong, He, Yan, Li, Juan, Yan, Hao-Wen, Su, Zhen, Cao, Xiao-Long, Li, Xiao-Bing · 2023 · Journal of thoracic disease · DOI

Full title: Efficiency and toxicity of nab-paclitaxel and camrelizumab in the second or above line treatment of advanced non-small cell lung cancer: a retrospective cohort study.

Authors: Yin, Chen, Zou, Guo-Rong, He, Yan, Li, Juan, Yan, Hao-Wen, Su, Zhen, Cao, Xiao-Long, Li, Xiao-Bing

Year: 2023

Venue: Journal of thoracic disease

DOI: https://doi.org/10.21037/jtd-23-387

Paper Complete response to pembrolizumab in mismatch repair-deficient urothelial carcinoma with local recurrence and recurrent upper tract urothelial carcinoma: a case report.

Shiraishi, Koichi, Shiota, Masaki, Fukuchi, Genshiro, Tanegashima, Tokiyoshi, Tsukahara, Shigehiro, Mutaguchi, Jun, Kobayashi, Satoshi, Matsumoto, Takashi, Oda, Yoshinao, Eto, Masatoshi · 2025 · International cancer conference journal · DOI

Full title: Complete response to pembrolizumab in mismatch repair-deficient urothelial carcinoma with local recurrence and recurrent upper tract urothelial carcinoma: a case report.

Authors: Shiraishi, Koichi, Shiota, Masaki, Fukuchi, Genshiro, Tanegashima, Tokiyoshi, Tsukahara, Shigehiro, Mutaguchi, Jun, Kobayashi, Satoshi, Matsumoto, Takashi, Oda, Yoshinao, Eto, Masatoshi

Year: 2025

Venue: International cancer conference journal

DOI: https://doi.org/10.1007/s13691-025-00774-x

Paper Immune-related adverse events in cancer patients treated with immune checkpoint inhibitors: A single-center experience.

Kaur, Aneet, Doberstein, Taylor, Amberker, Rachana Ramesh, Garje, Rohan, Field, Elizabeth Hirak, Singh, Namrata · 2019 · Medicine · DOI

Full title: Immune-related adverse events in cancer patients treated with immune checkpoint inhibitors: A single-center experience.

Authors: Kaur, Aneet, Doberstein, Taylor, Amberker, Rachana Ramesh, Garje, Rohan, Field, Elizabeth Hirak, Singh, Namrata

Year: 2019

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000017348

Paper SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, Anna, Iravani, Amir, Lasocki, Arian, Wallace, Roslyn, Weppler, Alison M., Au‐Yeung, George, Sachithanandan, Nirupa, Chiang, Cherie, Wentworth, John M., Colman, Peter G., Kay, Thomas William, Krishnamurthy, Balasubramanian, Sandhu, Shahneen · 2020 · Journal of the Endocrine Society · DOI

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, Anna, Iravani, Amir, Lasocki, Arian, Wallace, Roslyn, Weppler, Alison M., Au‐Yeung, George, Sachithanandan, Nirupa, Chiang, Cherie, Wentworth, John M., Colman, Peter G., Kay, Thomas William, Krishnamurthy, Balasubramanian, Sandhu, Shahneen

Year: 2020

Venue: Journal of the Endocrine Society

DOI: https://doi.org/10.1210/jendso/bvaa046.1693

Paper Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration of Anti-CTLA-4 Antibody Following the Discontinuation of Anti-PD-1 Antibody.

Shiba, Michiru, Inaba, Hidefumi, Ariyasu, Hiroyuki, Kawai, Shintaro, Inagaki, Yuko, Matsuno, Shohei, Iwakura, Hiroshi, Yamamoto, Yuki, Nishi, Masahiro, Akamizu, Takashi · 2018 · Internal medicine (Tokyo, Japan) · DOI

Full title: Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration of Anti-CTLA-4 Antibody Following the Discontinuation of Anti-PD-1 Antibody.

Authors: Shiba, Michiru, Inaba, Hidefumi, Ariyasu, Hiroyuki, Kawai, Shintaro, Inagaki, Yuko, Matsuno, Shohei, Iwakura, Hiroshi, Yamamoto, Yuki, Nishi, Masahiro, Akamizu, Takashi

Year: 2018

Venue: Internal medicine (Tokyo, Japan)

DOI: https://doi.org/10.2169/internalmedicine.9518-17

Paper Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions.

Zhang, Yi, Li, Zheng, Huang, Ying, Xu, Yong, Zou, Bingwen · 2024 · Expert review of clinical immunology · DOI

Full title: Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions.

Authors: Zhang, Yi, Li, Zheng, Huang, Ying, Xu, Yong, Zou, Bingwen

Year: 2024

Venue: Expert review of clinical immunology

DOI: https://doi.org/10.1080/1744666X.2024.2368194

Paper Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis.

Bomze, David, Meirson, Tomer, Hasan Ali, Omar, Goldman, Adam, Flatz, Lukas, Habot-Wilner, Zohar · 2022 · Ocular immunology and inflammation · DOI

Full title: Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis.

Authors: Bomze, David, Meirson, Tomer, Hasan Ali, Omar, Goldman, Adam, Flatz, Lukas, Habot-Wilner, Zohar

Year: 2022

Venue: Ocular immunology and inflammation

DOI: https://doi.org/10.1080/09273948.2020.1773867

Paper NRF2–COX2–PGE2 axis drives immune cold tumors and predicts resistance to combination immunotherapy in hepatocellular carcinoma

Yamamoto, Shunsuke, Kodama, Takahiro, Kuwano, Akifumi, Maesaka, Kazuki, Yoshida-Hashidate, Tomomi, Shindou, Hideo, Takeda, Haruhiko, Shirai, Kumiko, Myojin, Yuta, Murai, Kazuhiro, Makino, Yuki, Tahata, Yuki, Watanabe, Hiroko, Hosui, Atsushi, Nozaki, Yasutoshi, Nakabori, Tasuku, Ohkawa, Kazuyoshi, Tanaka, Satoshi, Nishio, Akira, Miyazaki, Masanori, Hikita, Hayato, Motomura, Kenta, Lujambio, Amaia, Taketomi, Akinobu, Ohno, Shinji, Takehara, Tetsuo · 2026 · Hepatology · DOI

Full title: NRF2–COX2–PGE2 axis drives immune cold tumors and predicts resistance to combination immunotherapy in hepatocellular carcinoma

Authors: Yamamoto, Shunsuke, Kodama, Takahiro, Kuwano, Akifumi, Maesaka, Kazuki, Yoshida-Hashidate, Tomomi, Shindou, Hideo, Takeda, Haruhiko, Shirai, Kumiko, Myojin, Yuta, Murai, Kazuhiro, Makino, Yuki, Tahata, Yuki, Watanabe, Hiroko, Hosui, Atsushi, Nozaki, Yasutoshi, Nakabori, Tasuku, Ohkawa, Kazuyoshi, Tanaka, Satoshi, Nishio, Akira, Miyazaki, Masanori, Hikita, Hayato, Motomura, Kenta, Lujambio, Amaia, Taketomi, Akinobu, Ohno, Shinji, Takehara, Tetsuo

Year: 2026

Venue: Hepatology

DOI: https://doi.org/10.1097/hep.0000000000001677

Paper Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Sakuishi, Kaori, Apétoh, Lionel, Sullivan, Jenna M., Blazar, Bruce R., Kuchroo, Vijay K., Anderson, Ana C. · 2010 · The Journal of Experimental Medicine · DOI

Full title: Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Authors: Sakuishi, Kaori, Apétoh, Lionel, Sullivan, Jenna M., Blazar, Bruce R., Kuchroo, Vijay K., Anderson, Ana C.

Year: 2010

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20100643

Paper Systemic impact on tumor growth after combined immuno-thermal ablation in a murine model of colorectal cancer.

Slovak, Ryan, Park, Hong‐Jai, Kamp, William M., Ludwig, Johannes, Kang, Insoo, Kim, Hyun S. · 2020 · Journal of Clinical Oncology · DOI

Full title: Systemic impact on tumor growth after combined immuno-thermal ablation in a murine model of colorectal cancer.

Authors: Slovak, Ryan, Park, Hong‐Jai, Kamp, William M., Ludwig, Johannes, Kang, Insoo, Kim, Hyun S.

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.4_suppl.198

Paper Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer.

Liu, Lina, Wang, Yuhua, Miao, Lei, Liu, Qi, Musetti, Sara, Li, Jun, Huang, Leaf · 2018 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer.

Authors: Liu, Lina, Wang, Yuhua, Miao, Lei, Liu, Qi, Musetti, Sara, Li, Jun, Huang, Leaf

Year: 2018

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1016/j.ymthe.2017.10.020

Paper Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer.

Fiegle, E, Doleschel, D, Koletnik, S, Rix, A, Weiskirchen, R, Borkham-Kamphorst, E, Kiessling, F, Lederle, W · 2019 · Neoplasia (New York, N.Y.) · DOI

Full title: Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer.

Authors: Fiegle, E, Doleschel, D, Koletnik, S, Rix, A, Weiskirchen, R, Borkham-Kamphorst, E, Kiessling, F, Lederle, W

Year: 2019

Venue: Neoplasia (New York, N.Y.)

DOI: https://doi.org/10.1016/j.neo.2019.07.006

Paper PD-1/PD-L1 inhibitors in endometrial cancer with high microsatellite instability: a Kaplan-Meier-derived patient data meta-analysis.

de Moraes, Francisco Cezar Aquino, Cavalcanti Souza, Maria Eduarda, Rodrigues Carlos, Maria Isadora, Kamitani, Hideki Zimermann, Burbano, Rommel Mario Rodríguez · 2026 · Expert review of anticancer therapy · DOI

Full title: PD-1/PD-L1 inhibitors in endometrial cancer with high microsatellite instability: a Kaplan-Meier-derived patient data meta-analysis.

Authors: de Moraes, Francisco Cezar Aquino, Cavalcanti Souza, Maria Eduarda, Rodrigues Carlos, Maria Isadora, Kamitani, Hideki Zimermann, Burbano, Rommel Mario Rodríguez

Year: 2026

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2025.2576617

Paper Retrospective study of the incidence of sarcoidosis-like reaction in patients treated with immunotherapy.

Li, Y, Flavell, R R, Juarez, R, Chow, M, Wu, C, Tsai, K, Daud, A, Behr, S C · 2023 · Clinical radiology · DOI

Full title: Retrospective study of the incidence of sarcoidosis-like reaction in patients treated with immunotherapy.

Authors: Li, Y, Flavell, R R, Juarez, R, Chow, M, Wu, C, Tsai, K, Daud, A, Behr, S C

Year: 2023

Venue: Clinical radiology

DOI: https://doi.org/10.1016/j.crad.2022.09.127

Paper Clinical outcomes of melanoma brain metastases treated with stereotactic radiosurgery and anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, BRAF inhibitor, or conventional chemotherapy.

Ahmed, K A, Abuodeh, Y A, Echevarria, M I, Arrington, J A, Stallworth, D G, Hogue, C, Naghavi, A O, Kim, S, Kim, Y, Patel, B G, Sarangkasiri, S, Johnstone, P A S, Sahebjam, S, Khushalani, N I, Forsyth, P A, Harrison, L B, Yu, M, Etame, A B, Caudell, J J · 2016 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Clinical outcomes of melanoma brain metastases treated with stereotactic radiosurgery and anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, BRAF inhibitor, or conventional chemotherapy.

Authors: Ahmed, K A, Abuodeh, Y A, Echevarria, M I, Arrington, J A, Stallworth, D G, Hogue, C, Naghavi, A O, Kim, S, Kim, Y, Patel, B G, Sarangkasiri, S, Johnstone, P A S, Sahebjam, S, Khushalani, N I, Forsyth, P A, Harrison, L B, Yu, M, Etame, A B, Caudell, J J

Year: 2016

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdw417

Paper Body mass index and immune-related adverse events in patients on immune checkpoint inhibitor therapies: a systematic review and meta-analysis.

Guzman-Prado, Yuli, Ben Shimol, Jennifer, Samson, Ondrej · 2021 · Cancer immunology, immunotherapy : CII · DOI

Full title: Body mass index and immune-related adverse events in patients on immune checkpoint inhibitor therapies: a systematic review and meta-analysis.

Authors: Guzman-Prado, Yuli, Ben Shimol, Jennifer, Samson, Ondrej

Year: 2021

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-020-02663-z

Paper Predictive factors for immunotherapy in melanoma.

Teixidó, Cristina, González-Cao, Maria, Karachaliou, Niki, Rosell, Rafael · 2015 · Annals of translational medicine · DOI

Full title: Predictive factors for immunotherapy in melanoma.

Authors: Teixidó, Cristina, González-Cao, Maria, Karachaliou, Niki, Rosell, Rafael

Year: 2015

Venue: Annals of translational medicine

DOI: https://doi.org/10.3978/j.issn.2305-5839.2015.05.07

Paper Is earlier better for melanoma checkpoint blockade?

Robert, Caroline · 2018 · Nature medicine · DOI

Full title: Is earlier better for melanoma checkpoint blockade?

Authors: Robert, Caroline

Year: 2018

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-018-0250-0

Paper Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer.

Greally, Megan, Chou, Joanne F, Chatila, Walid K, Margolis, Matthew, Capanu, Marinela, Hechtman, Jaclyn F, Tuvy, Yaelle, Kundra, Ritika, Daian, Foysal, Ladanyi, Marc, Kelsen, David P, Ilson, David H, Berger, Michael F, Tang, Laura H, Solit, David B, Diaz, Luis A, Schultz, Nikolaus, Janjigian, Yelena Y, Ku, Geoffrey Y · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer.

Authors: Greally, Megan, Chou, Joanne F, Chatila, Walid K, Margolis, Matthew, Capanu, Marinela, Hechtman, Jaclyn F, Tuvy, Yaelle, Kundra, Ritika, Daian, Foysal, Ladanyi, Marc, Kelsen, David P, Ilson, David H, Berger, Michael F, Tang, Laura H, Solit, David B, Diaz, Luis A, Schultz, Nikolaus, Janjigian, Yelena Y, Ku, Geoffrey Y

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-18-3603

Paper Ophthalmic Immune-Related Adverse Events after Anti-CTLA-4 or PD-1 Therapy Recorded in the American Academy of Ophthalmology Intelligent Research in Sight Registry.

Sun, Michel M, Kelly, Scott P, Mylavarapu Bs, Apoorva L, Holland, Gary N, Coleman, Anne L, Yu, Fei, Hsu Ms, Stephen, Lum, Flora, Gordon, Lynn K · 2021 · Ophthalmology · DOI

Full title: Ophthalmic Immune-Related Adverse Events after Anti-CTLA-4 or PD-1 Therapy Recorded in the American Academy of Ophthalmology Intelligent Research in Sight Registry.

Authors: Sun, Michel M, Kelly, Scott P, Mylavarapu Bs, Apoorva L, Holland, Gary N, Coleman, Anne L, Yu, Fei, Hsu Ms, Stephen, Lum, Flora, Gordon, Lynn K

Year: 2021

Venue: Ophthalmology

DOI: https://doi.org/10.1016/j.ophtha.2020.11.001

Paper Metastatic uveal melanoma showing durable response to anti-CTLA-4 and anti-PD-1 combination therapy after experiencing progression on anti-PD-1 therapy alone.

Afzal, Muhammad Zubair, Mabaera, Rodwell, Shirai, Keisuke · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Metastatic uveal melanoma showing durable response to anti-CTLA-4 and anti-PD-1 combination therapy after experiencing progression on anti-PD-1 therapy alone.

Authors: Afzal, Muhammad Zubair, Mabaera, Rodwell, Shirai, Keisuke

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0322-1

Paper Is there still a role for talimogene laherparepvec (T-VEC) in advanced melanoma? An indirect efficacy comparison of T-VEC plus ipilimumab combination therapy versus T-VEC alone as salvage therapy in unresectable metastatic melanoma.

Fazel, Mohammad, AlRawashdh, Neda, Alamer, Ahmad, Curiel-Lewandrowski, Clara, Abraham, Ivo · 2021 · Expert opinion on biological therapy · DOI

Full title: Is there still a role for talimogene laherparepvec (T-VEC) in advanced melanoma? An indirect efficacy comparison of T-VEC plus ipilimumab combination therapy versus T-VEC alone as salvage therapy in unresectable metastatic melanoma.

Authors: Fazel, Mohammad, AlRawashdh, Neda, Alamer, Ahmad, Curiel-Lewandrowski, Clara, Abraham, Ivo

Year: 2021

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2022.1998450

Paper The pan-cancer landscape of SMARCA4 and SMARCB1 alterations in a large cohort of Chinese patients.

Qingling Song, Junjie Xie, Minxiao Guan, Huijia Wu, Yan-Zhi Lv, Mengdi Yuan, Yu Wang, Jiaxing Zhao, Zeyu Jiang, Yafei Zhang, Xingxiang Pu · 2024 · Journal of Clinical Oncology · DOI

Full title: The pan-cancer landscape of SMARCA4 and SMARCB1 alterations in a large cohort of Chinese patients.

Authors: Qingling Song, Junjie Xie, Minxiao Guan, Huijia Wu, Yan-Zhi Lv, Mengdi Yuan, Yu Wang, Jiaxing Zhao, Zeyu Jiang, Yafei Zhang, Xingxiang Pu

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.e14636

Paper Efficacy and safety of combination immunotherapy for malignant solid tumors: A systematic review and meta-analysis.

Wei, Yuhan, Du, Qi, Jiang, Xiaoyue, Li, Li, Li, Teng, Li, Mengqi, Fan, Xueke, Li, Yingrui, Kariminia, Seyed, Li, Qin · 2019 · Critical reviews in oncology/hematology · DOI

Full title: Efficacy and safety of combination immunotherapy for malignant solid tumors: A systematic review and meta-analysis.

Authors: Wei, Yuhan, Du, Qi, Jiang, Xiaoyue, Li, Li, Li, Teng, Li, Mengqi, Fan, Xueke, Li, Yingrui, Kariminia, Seyed, Li, Qin

Year: 2019

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2019.04.008

Paper Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy.

Sax, Anna, May, Peter, Enssle, Stefan, Soliman, Nardine, Nedelko, Tatiana, Mandracci, Giada, Stögbauer, Fabian, Joachim, Laura, Winter, Christof, Bassermann, Florian, Steiger, Katja, El Khawanky, Nadia, Poeck, Hendrik, Heidegger, Simon · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy.

Authors: Sax, Anna, May, Peter, Enssle, Stefan, Soliman, Nardine, Nedelko, Tatiana, Mandracci, Giada, Stögbauer, Fabian, Joachim, Laura, Winter, Christof, Bassermann, Florian, Steiger, Katja, El Khawanky, Nadia, Poeck, Hendrik, Heidegger, Simon

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-010433

Paper Ipilimumab: an investigational immunotherapy for glioblastoma.

Youssef, Gilbert, Dietrich, Jorg · 2020 · Expert opinion on investigational drugs · DOI

Full title: Ipilimumab: an investigational immunotherapy for glioblastoma.

Authors: Youssef, Gilbert, Dietrich, Jorg

Year: 2020

Venue: Expert opinion on investigational drugs

DOI: https://doi.org/10.1080/13543784.2020.1826436

Paper Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1-Based Immunotherapy.

Lim, Su Y, Lee, Jenny H, Gide, Tuba N, Menzies, Alexander M, Guminski, Alexander, Carlino, Matteo S, Breen, Edmond J, Yang, Jean Y H, Ghazanfar, Shila, Kefford, Richard F, Scolyer, Richard A, Long, Georgina V, Rizos, Helen · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1-Based Immunotherapy.

Authors: Lim, Su Y, Lee, Jenny H, Gide, Tuba N, Menzies, Alexander M, Guminski, Alexander, Carlino, Matteo S, Breen, Edmond J, Yang, Jean Y H, Ghazanfar, Shila, Kefford, Richard F, Scolyer, Richard A, Long, Georgina V, Rizos, Helen

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-18-2795

Paper Safety of resuming anti-PD-1 in patients with immune-related adverse events (irAEs) during combined anti-CTLA-4 and anti-PD1 in metastatic melanoma.

Pollack, M H, Betof, A, Dearden, H, Rapazzo, K, Valentine, I, Brohl, A S, Ancell, K K, Long, G V, Menzies, A M, Eroglu, Z, Johnson, D B, Shoushtari, A N · 2018 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Safety of resuming anti-PD-1 in patients with immune-related adverse events (irAEs) during combined anti-CTLA-4 and anti-PD1 in metastatic melanoma.

Authors: Pollack, M H, Betof, A, Dearden, H, Rapazzo, K, Valentine, I, Brohl, A S, Ancell, K K, Long, G V, Menzies, A M, Eroglu, Z, Johnson, D B, Shoushtari, A N

Year: 2018

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdx642

Paper Manipulation of tumor microenvironment by induction of immunogenic cell death and immune check point inhibitors for enhancing the efficacy of cancer treatments.

Moridikia, Abdullah, Montazersaheb, Soheila, Molavi, Ommoleila · 2026 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Manipulation of tumor microenvironment by induction of immunogenic cell death and immune check point inhibitors for enhancing the efficacy of cancer treatments.

Authors: Moridikia, Abdullah, Montazersaheb, Soheila, Molavi, Ommoleila

Year: 2026

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2026.119118

Paper Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Full title: Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Year: 2024

DOI: https://doi.org/10.1158/2159-8290.c.7451438.v1

Paper Rational combination immunotherapeutic approaches for effective cancer treatment.

Phung, Cao Dai, Nguyen, Hanh Thuy, Tran, Tuan Hiep, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh · 2019 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Rational combination immunotherapeutic approaches for effective cancer treatment.

Authors: Phung, Cao Dai, Nguyen, Hanh Thuy, Tran, Tuan Hiep, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh

Year: 2019

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2018.12.020

Paper [Modern concepts of systemic treatment for adjuvant and palliative treatment of locally advanced or metastasized esophageal cancer].

Lorenzen, Sylvie, Reinacher-Schick, Anke, Masetti, Michael · 2021 · Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · DOI

Full title: [Modern concepts of systemic treatment for adjuvant and palliative treatment of locally advanced or metastasized esophageal cancer].

Authors: Lorenzen, Sylvie, Reinacher-Schick, Anke, Masetti, Michael

Year: 2021

Venue: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

DOI: https://doi.org/10.1007/s00104-021-01476-9

Paper Distinct Cytokine Signatures in Thyroiditis Induced by PD-1 or CTLA-4 Blockade: Insights from a New Mouse Model.

Ippolito, Silvia, Di Dalmazi, Giulia, Pani, Fabiana, Sabini, Elena, Caturegli, Patrizio · 2021 · Thyroid : official journal of the American Thyroid Association · DOI

Full title: Distinct Cytokine Signatures in Thyroiditis Induced by PD-1 or CTLA-4 Blockade: Insights from a New Mouse Model.

Authors: Ippolito, Silvia, Di Dalmazi, Giulia, Pani, Fabiana, Sabini, Elena, Caturegli, Patrizio

Year: 2021

Venue: Thyroid : official journal of the American Thyroid Association

DOI: https://doi.org/10.1089/thy.2021.0165

Paper HGG-01. DURABLE RESPONSE TO IMMUNOTHERAPY IN AN ADOLESCENT PATEINT WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY CMMRD AND SYNCHRONOUS THREE PRIMARY MALIGNANCIES

N. Mobarak, Fahad E. Alotabi, A. Balbaid, W. Shakweer, Rana Alrasheed, S. A. AlMalki, M. Alharbi, A. H. Alfakeeh · 2024 · Neuro-Oncology · DOI

Full title: HGG-01. DURABLE RESPONSE TO IMMUNOTHERAPY IN AN ADOLESCENT PATEINT WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY CMMRD AND SYNCHRONOUS THREE PRIMARY MALIGNANCIES

Authors: N. Mobarak, Fahad E. Alotabi, A. Balbaid, W. Shakweer, Rana Alrasheed, S. A. AlMalki, M. Alharbi, A. H. Alfakeeh

Year: 2024

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noae064.285

Paper Combined prostate cancer vaccine plus immune checkpoint inhibition synergizes to eliminate prostate cancer.

Carreno-Galeano, Gabriel, Dubey, Seema, Iczkowski, Kenneth A, Van Veldhuizen, Peter, Anele, Uzoma A, Messer, Jamie C, Ankem, Murali K, Karan, Dev · 2026 · iScience · DOI

Full title: Combined prostate cancer vaccine plus immune checkpoint inhibition synergizes to eliminate prostate cancer.

Authors: Carreno-Galeano, Gabriel, Dubey, Seema, Iczkowski, Kenneth A, Van Veldhuizen, Peter, Anele, Uzoma A, Messer, Jamie C, Ankem, Murali K, Karan, Dev

Year: 2026

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2025.114552

Paper A phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort.

Chae, Young Kwang, Othus, Megan, Patel, Sandip Pravin, Aljumaily, Raid, Win, Khine Z, Pejovic, Tanya, Thomas, Sajeve S, Robinson, William R, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine M, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle · 2025 · Cancer communications (London, England) · DOI

Full title: A phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort.

Authors: Chae, Young Kwang, Othus, Megan, Patel, Sandip Pravin, Aljumaily, Raid, Win, Khine Z, Pejovic, Tanya, Thomas, Sajeve S, Robinson, William R, Kim, Hye Sung, Chung, Liam Il-Young, McLeod, Christine M, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle

Year: 2025

Venue: Cancer communications (London, England)

DOI: https://doi.org/10.1002/cac2.70020

Paper Abstract 4286: TGF-β signature is a therapeutic biomarker for combination immunotherapy for hepatocellular carcinoma

Chen, Jian, Su, Xiaoping · 2020 · Cancer Research · DOI

Full title: Abstract 4286: TGF-β signature is a therapeutic biomarker for combination immunotherapy for hepatocellular carcinoma

Authors: Chen, Jian, Su, Xiaoping

Year: 2020

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2020-4286

Paper Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria

I. Matos, J. Martín-Liberal, A. García-Ruiz, C. Hierro, M. Ochoa de Olza, C. Viaplana, A. Azaro, M. Vieito, I. Braña, G. Mur, J. Ros, J. Mateos, G. Villacampa, R. Berché, Mafalda Oliveira, M. Alsina, E. Élez, A. Oaknin, E. Muñoz-Couselo, J. Carles, E. Felip, J. Rodón, J. Tabernero, R. Dienstmann, R. Pérez-López, E. Garralda · 2019 · Clinical Cancer Research · DOI

Full title: Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria

Authors: I. Matos, J. Martín-Liberal, A. García-Ruiz, C. Hierro, M. Ochoa de Olza, C. Viaplana, A. Azaro, M. Vieito, I. Braña, G. Mur, J. Ros, J. Mateos, G. Villacampa, R. Berché, Mafalda Oliveira, M. Alsina, E. Élez, A. Oaknin, E. Muñoz-Couselo, J. Carles, E. Felip, J. Rodón, J. Tabernero, R. Dienstmann, R. Pérez-López, E. Garralda

Year: 2019

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-19-2226

Paper Clinically approved combination immunotherapy: Current status, limitations, and future perspective.

Lu, Ligong, Zhan, Meixiao, Li, Xian-Yang, Zhang, Hui, Dauphars, Danielle J, Jiang, Jun, Yin, Hua, Li, Shi-You, Luo, Sheng, Li, Yong, He, You-Wen · 2022 · Current research in immunology · DOI

Full title: Clinically approved combination immunotherapy: Current status, limitations, and future perspective.

Authors: Lu, Ligong, Zhan, Meixiao, Li, Xian-Yang, Zhang, Hui, Dauphars, Danielle J, Jiang, Jun, Yin, Hua, Li, Shi-You, Luo, Sheng, Li, Yong, He, You-Wen

Year: 2022

Venue: Current research in immunology

DOI: https://doi.org/10.1016/j.crimmu.2022.05.003

Paper Sarcomatoid and Rhabdoid Renal Cell Carcinoma: Clinical, Pathologic, and Molecular Genetic Features.

Adeniran, Adebowale J, Shuch, Brian, Humphrey, Peter A · 2024 · The American journal of surgical pathology · DOI

Full title: Sarcomatoid and Rhabdoid Renal Cell Carcinoma: Clinical, Pathologic, and Molecular Genetic Features.

Authors: Adeniran, Adebowale J, Shuch, Brian, Humphrey, Peter A

Year: 2024

Venue: The American journal of surgical pathology

DOI: https://doi.org/10.1097/PAS.0000000000002233

Paper A comprehensive pan-cancer analysis of CD274 gene amplification, tumor mutation burden, microsatellite instability, and PD-L1 expression in Chinese cancer patients.

Gao, Guanghui, Zhang, Xiao-Dong, Qu, Hu, Yao, Bing, Zhou, Yuxi, Xiang, Jianxing, Chen, Chunxiang, Hou, Ting, Chen, Kai, Xu, Junying · 2021 · Annals of translational medicine · DOI

Full title: A comprehensive pan-cancer analysis of CD274 gene amplification, tumor mutation burden, microsatellite instability, and PD-L1 expression in Chinese cancer patients.

Authors: Gao, Guanghui, Zhang, Xiao-Dong, Qu, Hu, Yao, Bing, Zhou, Yuxi, Xiang, Jianxing, Chen, Chunxiang, Hou, Ting, Chen, Kai, Xu, Junying

Year: 2021

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm-21-853

Paper The sound and surprise: overlapping meta-analyses on the topic of safety and efficacy of PD-1 and PD-L1 inhibitors in the treatment of non-small cell lung cancer.

Ou, Shun-Long, Luo, Jing, Wang, Song, Li, Kai-Yue, Du, Su-Ya, Jiang, Qian · 2023 · European journal of clinical pharmacology · DOI

Full title: The sound and surprise: overlapping meta-analyses on the topic of safety and efficacy of PD-1 and PD-L1 inhibitors in the treatment of non-small cell lung cancer.

Authors: Ou, Shun-Long, Luo, Jing, Wang, Song, Li, Kai-Yue, Du, Su-Ya, Jiang, Qian

Year: 2023

Venue: European journal of clinical pharmacology

DOI: https://doi.org/10.1007/s00228-023-03577-2

Paper Pancreatic injury following immune checkpoint inhibitors: A systematic review and meta-analysis.

Zhang, Tian, Wang, Yi, Shi, Chunhui, Liu, Xiaochun, Lv, Shangbin, Wang, Xin, Li, Weihong · 2022 · Frontiers in pharmacology · DOI

Full title: Pancreatic injury following immune checkpoint inhibitors: A systematic review and meta-analysis.

Authors: Zhang, Tian, Wang, Yi, Shi, Chunhui, Liu, Xiaochun, Lv, Shangbin, Wang, Xin, Li, Weihong

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.955701

Paper DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy.

Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M, Shore, Gordon C, Roulston, Anne · 2018 · Anti-cancer drugs · DOI

Full title: DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy.

Authors: Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M, Shore, Gordon C, Roulston, Anne

Year: 2018

Venue: Anti-cancer drugs

DOI: https://doi.org/10.1097/CAD.0000000000000653

Paper Opportunities for using in silico-based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors.

Peer, Cody J, Goldstein, Daniel A, Goodell, Jennifer C, Nguyen, Ryan, Figg, William D, Ratain, Mark J · 2020 · British journal of clinical pharmacology · DOI

Full title: Opportunities for using in silico-based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors.

Authors: Peer, Cody J, Goldstein, Daniel A, Goodell, Jennifer C, Nguyen, Ryan, Figg, William D, Ratain, Mark J

Year: 2020

Venue: British journal of clinical pharmacology

DOI: https://doi.org/10.1111/bcp.14369

Paper Anti-KIT Monoclonal Antibody Treatment Enhances the Antitumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression.

Garton, Andrew J, Seibel, Scott, Lopresti-Morrow, Lori, Crew, Linda, Janson, Neal, Mandiyan, Sreekala, Trombetta, E Sergio, Pankratz, Shannon, LaVallee, Theresa M, Gedrich, Richard · 2017 · Molecular cancer therapeutics · DOI

Full title: Anti-KIT Monoclonal Antibody Treatment Enhances the Antitumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression.

Authors: Garton, Andrew J, Seibel, Scott, Lopresti-Morrow, Lori, Crew, Linda, Janson, Neal, Mandiyan, Sreekala, Trombetta, E Sergio, Pankratz, Shannon, LaVallee, Theresa M, Gedrich, Richard

Year: 2017

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-16-0676

Paper Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials.

Verheijden, Rik J, de Groot, Jolien S, Fabriek, Babs O, Hew, Miki N, May, Anne M, Suijkerbuijk, Karijn P M · 2024 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · DOI

Full title: Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials.

Authors: Verheijden, Rik J, de Groot, Jolien S, Fabriek, Babs O, Hew, Miki N, May, Anne M, Suijkerbuijk, Karijn P M

Year: 2024

Venue: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

DOI: https://doi.org/10.1200/JCO.24.00191

Paper Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy.

Kwon, E D, Foster, B A, Hurwitz, A A, Madias, C, Allison, J P, Greenberg, N M, Burg, M B · 1999 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy.

Authors: Kwon, E D, Foster, B A, Hurwitz, A A, Madias, C, Allison, J P, Greenberg, N M, Burg, M B

Year: 1999

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.96.26.15074

Paper Building on the anti-PD1/PD-L1 backbone: combination immunotherapy for cancer

Garces, Alvaro Ingles, Au, Lewis, Mason, Robert M., Thomas, Jennifer, Larkin, James · 2019 · Expert Opinion on Investigational Drugs · DOI

Full title: Building on the anti-PD1/PD-L1 backbone: combination immunotherapy for cancer

Authors: Garces, Alvaro Ingles, Au, Lewis, Mason, Robert M., Thomas, Jennifer, Larkin, James

Year: 2019

Venue: Expert Opinion on Investigational Drugs

DOI: https://doi.org/10.1080/13543784.2019.1649657

Paper Abstract 2951: NI-2901, an affinity-optimized CD47xPD-L1 bispecific antibody for dual immune checkpoint blockade

Chauchet, Xavier, Calloud, Sébastien, Lloveras, Pauline, Bosson, Nicolas, Legrand, Margaux, Chatel, Laurence, Cons, Laura, Lesnier, Adeline, Malinge, Pauline, Pontini, Guillemette, Guillamo, Christophe, Shchelokov, Dmitry, Demin, Oleg, Ravn, Ulla, Moine, Valéry, Daubeuf, Bruno, Magistrelli, Giovanni, Poitevin, Yves, Salgado-Pires, Susana, Shang, Limin, Fischer, Nicolas, Ferlin, Walter, Masternak, Krzysztof · 2023 · Cancer Research · DOI

Full title: Abstract 2951: NI-2901, an affinity-optimized CD47xPD-L1 bispecific antibody for dual immune checkpoint blockade

Authors: Chauchet, Xavier, Calloud, Sébastien, Lloveras, Pauline, Bosson, Nicolas, Legrand, Margaux, Chatel, Laurence, Cons, Laura, Lesnier, Adeline, Malinge, Pauline, Pontini, Guillemette, Guillamo, Christophe, Shchelokov, Dmitry, Demin, Oleg, Ravn, Ulla, Moine, Valéry, Daubeuf, Bruno, Magistrelli, Giovanni, Poitevin, Yves, Salgado-Pires, Susana, Shang, Limin, Fischer, Nicolas, Ferlin, Walter, Masternak, Krzysztof

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-2951

Paper Regimen Selection for Chemoimmunotherapy in Nonsquamous Non-Small Cell Lung Cancer with Low PD-L1 Expression: A Multicenter Retrospective Cohort Study.

Hata, Tae, Yamada, Tadaaki, Goto, Yasuhiro, Amano, Akihiko, Negi, Yoshiki, Watanabe, Satoshi, Furuya, Naoki, Oba, Tomohiro, Ikoma, Tatsuki, Nakao, Akira, Tanimura, Keiko, Taniguchi, Hirokazu, Yoshimura, Akihiro, Fukui, Tomoya, Murata, Daiki, Kaira, Kyoichi, Shiotsu, Shinsuke, Hibino, Makoto, Okada, Asuka, Chihara, Yusuke, Kawachi, Hayato, Kijima, Takashi, Takayama, Koichi · 2025 · Clinical lung cancer · DOI

Full title: Regimen Selection for Chemoimmunotherapy in Nonsquamous Non-Small Cell Lung Cancer with Low PD-L1 Expression: A Multicenter Retrospective Cohort Study.

Authors: Hata, Tae, Yamada, Tadaaki, Goto, Yasuhiro, Amano, Akihiko, Negi, Yoshiki, Watanabe, Satoshi, Furuya, Naoki, Oba, Tomohiro, Ikoma, Tatsuki, Nakao, Akira, Tanimura, Keiko, Taniguchi, Hirokazu, Yoshimura, Akihiro, Fukui, Tomoya, Murata, Daiki, Kaira, Kyoichi, Shiotsu, Shinsuke, Hibino, Makoto, Okada, Asuka, Chihara, Yusuke, Kawachi, Hayato, Kijima, Takashi, Takayama, Koichi

Year: 2025

Venue: Clinical lung cancer

DOI: https://doi.org/10.1016/j.cllc.2025.01.002

Paper Design and conduct of early clinical studies of immunotherapy agent combinations: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

Smoragiewicz, Martin, Bogaerts, Jan, Calvo, Emiliano, Marabelle, Aurélien, Perrone, Andrea, Seymour, Lesley, Shalabi, A., Siu, Lillian L., Tabernero, Josep, Giaccone, Giuseppe, Atkins, Michael B., Banerji, Udai, Bates, SE, Bogaerts, Jan, Calvo, Emiliano, Braud, Filippo de, Douillard, Jean-Yves, Giaccone, Giuseppe, Keegan, Patricia, Kumar, Rajeev, LoRusso, Patricia, Marabelle, Aurélien, Perrone, Andrea, Pignatti, Francesco, Plummer, Ruth, Seymour, Lesley, Schwartz, Gary E., Shalabi, A., Shapiro, G., Siu, Lillian L., Smoragiewicz, Martin, Tabernero, Josep, Therasse, P., Yang, Anli · 2018 · Annals of Oncology · DOI

Full title: Design and conduct of early clinical studies of immunotherapy agent combinations: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

Authors: Smoragiewicz, Martin, Bogaerts, Jan, Calvo, Emiliano, Marabelle, Aurélien, Perrone, Andrea, Seymour, Lesley, Shalabi, A., Siu, Lillian L., Tabernero, Josep, Giaccone, Giuseppe, Atkins, Michael B., Banerji, Udai, Bates, SE, Bogaerts, Jan, Calvo, Emiliano, Braud, Filippo de, Douillard, Jean-Yves, Giaccone, Giuseppe, Keegan, Patricia, Kumar, Rajeev, LoRusso, Patricia, Marabelle, Aurélien, Perrone, Andrea, Pignatti, Francesco, Plummer, Ruth, Seymour, Lesley, Schwartz, Gary E., Shalabi, A., Shapiro, G., Siu, Lillian L., Smoragiewicz, Martin, Tabernero, Josep, Therasse, P., Yang, Anli

Year: 2018

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdy398

Paper [Progression of immunotherapy in gastric cancer].

Wei, Xiaoli, Xu, Ruihua · 2016 · Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

Full title: [Progression of immunotherapy in gastric cancer].

Authors: Wei, Xiaoli, Xu, Ruihua

Year: 2016

Venue: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

Paper Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy.

Cao, Zeya, Wang, Youping, Cheng, Shih-Chin, He, Nanhai · 2025 · Journal of leukocyte biology · DOI

Full title: Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy.

Authors: Cao, Zeya, Wang, Youping, Cheng, Shih-Chin, He, Nanhai

Year: 2025

Venue: Journal of leukocyte biology

DOI: https://doi.org/10.1093/jleuko/qiae158

Paper A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors SWOG S1609: Vulvar Cancers.

Chae, Young Kwang, Corthell, Lucy, Patel, Sandip Pravin, Edwards, Robert, Scalici, Jennifer M, Kim, Hye Sung, Chung, Liam Il-Young, Othus, Megan, McLeod, Christine M, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors SWOG S1609: Vulvar Cancers.

Authors: Chae, Young Kwang, Corthell, Lucy, Patel, Sandip Pravin, Edwards, Robert, Scalici, Jennifer M, Kim, Hye Sung, Chung, Liam Il-Young, Othus, Megan, McLeod, Christine M, Chen, Helen X, Sharon, Elad, Streicher, Howard, Ryan, Christopher W, Blanke, Charles D, Kurzrock, Razelle

Year: 2025

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-24-1957

Paper The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma.

Merle, Philippe · 2021 · Cancers · DOI

Full title: The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma.

Authors: Merle, Philippe

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13020238

Paper Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma

Motzer, Robert J., Choueiri, Toni K., McDermott, David F., Powles, Thomas, Vano, Yann, Gupta, Saurabh, Yao, Jin, Han, G. Celine, Ammar, Ron, Papillon‐Cavanagh, Simon, Saggi, Shruti Shally, McHenry, M. Brent, Ross‐Macdonald, Petra, Wind‐Rotolo, Megan · 2022 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma

Authors: Motzer, Robert J., Choueiri, Toni K., McDermott, David F., Powles, Thomas, Vano, Yann, Gupta, Saurabh, Yao, Jin, Han, G. Celine, Ammar, Ron, Papillon‐Cavanagh, Simon, Saggi, Shruti Shally, McHenry, M. Brent, Ross‐Macdonald, Petra, Wind‐Rotolo, Megan

Year: 2022

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2021-004316

Paper Combination immunotherapy for pancreatic cancer: challenges and future considerations.

Gössling, Gustavo C L, Zhen, David B, Pillarisetty, Venu G, Chiorean, E Gabriela · 2022 · Expert review of clinical immunology · DOI

Full title: Combination immunotherapy for pancreatic cancer: challenges and future considerations.

Authors: Gössling, Gustavo C L, Zhen, David B, Pillarisetty, Venu G, Chiorean, E Gabriela

Year: 2022

Venue: Expert review of clinical immunology

DOI: https://doi.org/10.1080/1744666X.2022.2120471

Paper Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.

Newton, Jared M, Hanoteau, Aurelie, Liu, Hsuan-Chen, Gaspero, Angelina, Parikh, Falguni, Gartrell-Corrado, Robyn D, Hart, Thomas D, Laoui, Damya, Van Ginderachter, Jo A, Dharmaraj, Neeraja, Spanos, William C, Saenger, Yvonne, Young, Simon, Sikora, Andrew G · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.

Authors: Newton, Jared M, Hanoteau, Aurelie, Liu, Hsuan-Chen, Gaspero, Angelina, Parikh, Falguni, Gartrell-Corrado, Robyn D, Hart, Thomas D, Laoui, Damya, Van Ginderachter, Jo A, Dharmaraj, Neeraja, Spanos, William C, Saenger, Yvonne, Young, Simon, Sikora, Andrew G

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0698-6

Paper Exosomal PD-L1 in non-small cell lung Cancer: Implications for immune evasion and resistance to immunotherapy.

Mojtaba Tarin, Mahsa Akbari Oryani, Hossein Javid, Mehdi Karimi-Shahri · 2025 · International Immunopharmacology · DOI

Full title: Exosomal PD-L1 in non-small cell lung Cancer: Implications for immune evasion and resistance to immunotherapy.

Authors: Mojtaba Tarin, Mahsa Akbari Oryani, Hossein Javid, Mehdi Karimi-Shahri

Year: 2025

Venue: International Immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.114519

Paper Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

Peranzoni, Elisa, Lemoine, Jean, Vimeux, Lene, Feuillet, Vincent, Barrin, Sarah, Kantari‐Mimoun, Chahrazade, Bercovici, Nadège, Guérin, Marion V., Biton, Jérôme, Ouakrim, Hanane, Régnier, Fabienne, Lupo, Audrey, Alifano, Marco, Damotte, Diane, Donnadieu, Emmanuel · 2018 · Proceedings of the National Academy of Sciences · DOI

Full title: Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

Authors: Peranzoni, Elisa, Lemoine, Jean, Vimeux, Lene, Feuillet, Vincent, Barrin, Sarah, Kantari‐Mimoun, Chahrazade, Bercovici, Nadège, Guérin, Marion V., Biton, Jérôme, Ouakrim, Hanane, Régnier, Fabienne, Lupo, Audrey, Alifano, Marco, Damotte, Diane, Donnadieu, Emmanuel

Year: 2018

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1720948115

Paper Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

Socinski, Mark A., Jotte, Robert M., Cappuzzo, Federico, Orlandi, Francesco, Stroyakovskiy, Daniil, Nogami, Naoyuki, Rodríguez‐Abreu, Delvys, Moro‐Sibilot, Denis, Thomas, Christian A., Barlési, Fabrice, Finley, Gene Grant, Kelsch, Claudia, Lee, Anthony, Coleman, Shelley, Deng, Yu, Shen, Yijing, Kowanetz, Marcin, López-Chávez, Ariel, Sandler, Alan, Reck, Martin · 2018 · New England Journal of Medicine · DOI

Full title: Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

Authors: Socinski, Mark A., Jotte, Robert M., Cappuzzo, Federico, Orlandi, Francesco, Stroyakovskiy, Daniil, Nogami, Naoyuki, Rodríguez‐Abreu, Delvys, Moro‐Sibilot, Denis, Thomas, Christian A., Barlési, Fabrice, Finley, Gene Grant, Kelsch, Claudia, Lee, Anthony, Coleman, Shelley, Deng, Yu, Shen, Yijing, Kowanetz, Marcin, López-Chávez, Ariel, Sandler, Alan, Reck, Martin

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1716948

Paper The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer.

Qu, Jingjing, Mei, Quanhui, Liu, Li, Cheng, Tianli, Wang, Peng, Chen, Lijun, Zhou, Jianying · 2021 · Therapeutic advances in medical oncology · DOI

Full title: The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer.

Authors: Qu, Jingjing, Mei, Quanhui, Liu, Li, Cheng, Tianli, Wang, Peng, Chen, Lijun, Zhou, Jianying

Year: 2021

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758835921992968

Paper Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

Dhodapkar, Madhav V., Sznol, Mario, Zhao, Biwei, Wang, Ding, Carvajal, Richard D., Keohan, Mary Louise, Chuang, Ellen, Sanborn, Rachel E., Lutzky, Jose, Powderly, John D., Kluger, Harriet M., Tejwani, Sheela, Green, Jennifer, Ramakrishna, Venky, Crocker, Andrea, Vitale, Laura, Yellin, Michael, Davis, Thomas A., Keler, Tibor · 2014 · Science Translational Medicine · DOI

Full title: Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

Authors: Dhodapkar, Madhav V., Sznol, Mario, Zhao, Biwei, Wang, Ding, Carvajal, Richard D., Keohan, Mary Louise, Chuang, Ellen, Sanborn, Rachel E., Lutzky, Jose, Powderly, John D., Kluger, Harriet M., Tejwani, Sheela, Green, Jennifer, Ramakrishna, Venky, Crocker, Andrea, Vitale, Laura, Yellin, Michael, Davis, Thomas A., Keler, Tibor

Year: 2014

Venue: Science Translational Medicine

DOI: https://doi.org/10.1126/scitranslmed.3008068

Paper Recurrent Pneumonitis in Patients with Melanoma Treated with Immune Checkpoint Inhibitors.

Asher, Nethanel, Marom, Edith M, Ben-Betzalel, Guy, Baruch, Erez Nissim, Steinberg-Silman, Yael, Schachter, Jacob, Shapira-Frommer, Ronnie, Markel, Gal · 2019 · The oncologist · DOI

Full title: Recurrent Pneumonitis in Patients with Melanoma Treated with Immune Checkpoint Inhibitors.

Authors: Asher, Nethanel, Marom, Edith M, Ben-Betzalel, Guy, Baruch, Erez Nissim, Steinberg-Silman, Yael, Schachter, Jacob, Shapira-Frommer, Ronnie, Markel, Gal

Year: 2019

Venue: The oncologist

DOI: https://doi.org/10.1634/theoncologist.2018-0352

Paper Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs

Haanen, John B.A.G. · 2019 · ESMO Open · DOI

Full title: Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs

Authors: Haanen, John B.A.G.

Year: 2019

Venue: ESMO Open

DOI: https://doi.org/10.1136/esmoopen-2019-000557

Paper Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors.

R. Grosser, L. Cherkassky, Navin K Chintala, P. Adusumilli · 2019 · Cancer Cell · DOI

Full title: Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors.

Authors: R. Grosser, L. Cherkassky, Navin K Chintala, P. Adusumilli

Year: 2019

Venue: Cancer Cell

DOI: https://doi.org/10.1016/j.ccell.2019.09.006

Paper The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma.

Mahoney, Kathleen M, Freeman, Gordon J, McDermott, David F · 2015 · Clinical therapeutics · DOI

Full title: The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma.

Authors: Mahoney, Kathleen M, Freeman, Gordon J, McDermott, David F

Year: 2015

Venue: Clinical therapeutics

DOI: https://doi.org/10.1016/j.clinthera.2015.02.018

Paper Effect of combination immunotherapy on tumor growth, survival, and intratumoral immune infiltration in transgenic murine model of melanoma.

Gartrell, Robyn D., Blake, Zoë, Esancy, Camden L., Pérez‐Lorenzo, Rolando, Rizk, Emanuelle M., Fu, Yichun, Yang, Chen, Saenger, Yvonne M. · 2018 · Journal of Clinical Oncology · DOI

Full title: Effect of combination immunotherapy on tumor growth, survival, and intratumoral immune infiltration in transgenic murine model of melanoma.

Authors: Gartrell, Robyn D., Blake, Zoë, Esancy, Camden L., Pérez‐Lorenzo, Rolando, Rizk, Emanuelle M., Fu, Yichun, Yang, Chen, Saenger, Yvonne M.

Year: 2018

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2018.36.15_suppl.e21610

Paper Bronchoscopic intratumoural therapies for non-small cell lung cancer

DeMaio, Andrew, Sterman, Daniel H. · 2020 · European Respiratory Review · DOI

Full title: Bronchoscopic intratumoural therapies for non-small cell lung cancer

Authors: DeMaio, Andrew, Sterman, Daniel H.

Year: 2020

Venue: European Respiratory Review

DOI: https://doi.org/10.1183/16000617.0028-2020

Paper Sustained clinico-radiologic response to anti-cytotoxic T lymphocyte antigen 4 antibody therapy in metastatic myxoid liposarcoma.

Dasanu, Constantin A · 2017 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · DOI

Full title: Sustained clinico-radiologic response to anti-cytotoxic T lymphocyte antigen 4 antibody therapy in metastatic myxoid liposarcoma.

Authors: Dasanu, Constantin A

Year: 2017

Venue: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

DOI: https://doi.org/10.1177/1078155216664202

Paper Advances in mRNA-Based Melanoma Vaccines: A Narrative Review of Lipid Nanoparticle and Dendritic Cell Delivery Platforms

Connor K. Sisk, Laci M. Turner, Shafkat Meraj, Nabiha Yusuf · 2026 · Cells · DOI

Full title: Advances in mRNA-Based Melanoma Vaccines: A Narrative Review of Lipid Nanoparticle and Dendritic Cell Delivery Platforms

Authors: Connor K. Sisk, Laci M. Turner, Shafkat Meraj, Nabiha Yusuf

Year: 2026

Venue: Cells

DOI: https://doi.org/10.3390/cells15020099

Paper Immunotherapy of Ipilimumab and Nivolumab in Patients with Advanced Neuroendocrine Tumors: A Subgroup Analysis of the CA209-538 Clinical Trial for Rare Cancers.

Klein, Oliver, Kee, Damien, Markman, Ben, Michael, Michael, Underhill, Craig, Carlino, Matteo S, Jackett, Louise, Lum, Caroline, Scott, Clare, Nagrial, Adnan, Behren, Andreas, So, Jane Y, Palmer, Jodie, Cebon, Jonathan · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Immunotherapy of Ipilimumab and Nivolumab in Patients with Advanced Neuroendocrine Tumors: A Subgroup Analysis of the CA209-538 Clinical Trial for Rare Cancers.

Authors: Klein, Oliver, Kee, Damien, Markman, Ben, Michael, Michael, Underhill, Craig, Carlino, Matteo S, Jackett, Louise, Lum, Caroline, Scott, Clare, Nagrial, Adnan, Behren, Andreas, So, Jane Y, Palmer, Jodie, Cebon, Jonathan

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-0621

Paper Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome.

Kanie, Keitaro, Iguchi, Genzo, Bando, Hironori, Urai, Shin, Shichi, Hiroki, Fujita, Yasunori, Matsumoto, Ryusaku, Suda, Kentaro, Yamamoto, Masaaki, Fukuoka, Hidenori, Ogawa, Wataru, Takahashi, Yutaka · 2021 · Cancer immunology, immunotherapy : CII · DOI

Full title: Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome.

Authors: Kanie, Keitaro, Iguchi, Genzo, Bando, Hironori, Urai, Shin, Shichi, Hiroki, Fujita, Yasunori, Matsumoto, Ryusaku, Suda, Kentaro, Yamamoto, Masaaki, Fukuoka, Hidenori, Ogawa, Wataru, Takahashi, Yutaka

Year: 2021

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-021-02955-y

Paper Design and Characterization of Prodrugged Anti-CTLA-4 Antibodies.

Yamazoe, Sayumi, Huber, Mary, Kotapati, Srikanth, Akter, Rahima, Jashnani, Aarti, Deol, Suprit, Bee, Christine, Engelhart, John, Poudel, Yam B, Krystek, Stanley, Haugner, John, Srinivasan, Mohan, Rajpal, Arvind, Zhang, Yong, Strop, Pavel, Rao, Chetana · 2025 · Chembiochem : a European journal of chemical biology · DOI

Full title: Design and Characterization of Prodrugged Anti-CTLA-4 Antibodies.

Authors: Yamazoe, Sayumi, Huber, Mary, Kotapati, Srikanth, Akter, Rahima, Jashnani, Aarti, Deol, Suprit, Bee, Christine, Engelhart, John, Poudel, Yam B, Krystek, Stanley, Haugner, John, Srinivasan, Mohan, Rajpal, Arvind, Zhang, Yong, Strop, Pavel, Rao, Chetana

Year: 2025

Venue: Chembiochem : a European journal of chemical biology

DOI: https://doi.org/10.1002/cbic.202500304

Paper T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regression.

Andersen, R, Borch, T H, Draghi, A, Gokuldass, A, Rana, M A H, Pedersen, M, Nielsen, M, Kongsted, P, Kjeldsen, J W, Westergaard, M C W, Radic, H D, Chamberlain, C A, Hölmich, L R, Hendel, H W, Larsen, M S, Met, Ö, Svane, I M, Donia, M · 2018 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regression.

Authors: Andersen, R, Borch, T H, Draghi, A, Gokuldass, A, Rana, M A H, Pedersen, M, Nielsen, M, Kongsted, P, Kjeldsen, J W, Westergaard, M C W, Radic, H D, Chamberlain, C A, Hölmich, L R, Hendel, H W, Larsen, M S, Met, Ö, Svane, I M, Donia, M

Year: 2018

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdy139

Paper Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model.

Sorensen, Maria R, Holst, Peter J, Steffensen, Maria A, Christensen, Jan P, Thomsen, Allan R · 2010 · Vaccine · DOI

Full title: Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model.

Authors: Sorensen, Maria R, Holst, Peter J, Steffensen, Maria A, Christensen, Jan P, Thomsen, Allan R

Year: 2010

Venue: Vaccine

DOI: https://doi.org/10.1016/j.vaccine.2010.07.066

Paper At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy.

Intlekofer, Andrew M, Thompson, Craig B · 2013 · Journal of leukocyte biology · DOI

Full title: At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy.

Authors: Intlekofer, Andrew M, Thompson, Craig B

Year: 2013

Venue: Journal of leukocyte biology

DOI: https://doi.org/10.1189/jlb.1212621

Paper [Immune checkpoints inhibitors: Recent data from ASCO's meeting 2017 and perspectives].

Kfoury, Maria, Disdero, Valentine, Vicier, Cécilé, Le Saux, Olivia, Gougis, Paul, Sajous, Christophe, Vignot, Stéphane · 2018 · Bulletin du cancer · DOI

Full title: [Immune checkpoints inhibitors: Recent data from ASCO's meeting 2017 and perspectives].

Authors: Kfoury, Maria, Disdero, Valentine, Vicier, Cécilé, Le Saux, Olivia, Gougis, Paul, Sajous, Christophe, Vignot, Stéphane

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2018.04.011

Paper Combination therapy with PD-1 or PD-L1 inhibitors for cancer.

Hayashi, Hidetoshi, Nakagawa, Kazuhiko · 2020 · International journal of clinical oncology · DOI

Full title: Combination therapy with PD-1 or PD-L1 inhibitors for cancer.

Authors: Hayashi, Hidetoshi, Nakagawa, Kazuhiko

Year: 2020

Venue: International journal of clinical oncology

DOI: https://doi.org/10.1007/s10147-019-01548-1

Paper Ansofaxine suppressed NSCLC progression by increasing sensitization to combination immunotherapy.

Gui, Huan, Nie, Yujie, Yuan, Haohua, Wang, Mengjiao, Li, Linzhao, Zhu, Lan, Chen, Shuanghui, Jing, Qianyu, Wan, Quan, Lv, Hang, Nie, Yingjie, Zhang, Xiangyan · 2025 · International immunopharmacology · DOI

Full title: Ansofaxine suppressed NSCLC progression by increasing sensitization to combination immunotherapy.

Authors: Gui, Huan, Nie, Yujie, Yuan, Haohua, Wang, Mengjiao, Li, Linzhao, Zhu, Lan, Chen, Shuanghui, Jing, Qianyu, Wan, Quan, Lv, Hang, Nie, Yingjie, Zhang, Xiangyan

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2024.113918

Paper Global Disproportionality Analysis of Adverse Event Reports on Interstitial Lung Diseases for Cancer-Targeted Therapies, 1968-2024.

Jeong, Jinyoung, Kim, Hyunjee, Lee, Sooji, Hwang, Jiyoung, Smith, Lee, Woo, Ho Geol, Cho, Jaehyeong, Yon, Dong Keon · 2026 · Respirology (Carlton, Vic.) · DOI

Full title: Global Disproportionality Analysis of Adverse Event Reports on Interstitial Lung Diseases for Cancer-Targeted Therapies, 1968-2024.

Authors: Jeong, Jinyoung, Kim, Hyunjee, Lee, Sooji, Hwang, Jiyoung, Smith, Lee, Woo, Ho Geol, Cho, Jaehyeong, Yon, Dong Keon

Year: 2026

Venue: Respirology (Carlton, Vic.)

DOI: https://doi.org/10.1002/resp.70135

Paper Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors.

Agarwalla, Pankaj, Barnard, Zachary, Fecci, Peter, Dranoff, Glenn, Curry, William T · 2012 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors.

Authors: Agarwalla, Pankaj, Barnard, Zachary, Fecci, Peter, Dranoff, Glenn, Curry, William T

Year: 2012

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0b013e3182562d59

Paper PD-1-mediated inhibition of T cell activation: Mechanisms and strategies for cancer combination immunotherapy.

Liu, Rui, Li, Hui-Fang, Li, Shu · 2024 · Cell insight · DOI

Full title: PD-1-mediated inhibition of T cell activation: Mechanisms and strategies for cancer combination immunotherapy.

Authors: Liu, Rui, Li, Hui-Fang, Li, Shu

Year: 2024

Venue: Cell insight

DOI: https://doi.org/10.1016/j.cellin.2024.100146

Paper Combination Immunotherapy of Oncolytic Flu-Vectored Virus and Programmed Cell Death 1 Blockade Enhances Antitumor Activity in Hepatocellular Carcinoma

Yu, Hongyu, Sun, Fang, Xu, Yan, Yang, Hao, Tian, Chongyu, Li, Cong, Kang, Yimin, HAO, Lei, Yang, Penghui · 2024 · Human Gene Therapy · DOI

Full title: Combination Immunotherapy of Oncolytic Flu-Vectored Virus and Programmed Cell Death 1 Blockade Enhances Antitumor Activity in Hepatocellular Carcinoma

Authors: Yu, Hongyu, Sun, Fang, Xu, Yan, Yang, Hao, Tian, Chongyu, Li, Cong, Kang, Yimin, HAO, Lei, Yang, Penghui

Year: 2024

Venue: Human Gene Therapy

DOI: https://doi.org/10.1089/hum.2023.150

Paper First-line treatment of extensive-stage small cell lung cancer with immune checkpoint inhibitors acting on different targets: a systematic review and network meta-analysis

Meng Li, Yu-zhu Chen, Dazhong Chen, Yang Wang, Hong-Li Zhao · 2025 · Translational Cancer Research · DOI

Full title: First-line treatment of extensive-stage small cell lung cancer with immune checkpoint inhibitors acting on different targets: a systematic review and network meta-analysis

Authors: Meng Li, Yu-zhu Chen, Dazhong Chen, Yang Wang, Hong-Li Zhao

Year: 2025

Venue: Translational Cancer Research

DOI: https://doi.org/10.21037/tcr-2025-430

Paper Immune checkpoint inhibitors in NSCLC.

Johnson, Douglas B, Rioth, Matthew J, Horn, Leora · 2014 · Current treatment options in oncology · DOI

Full title: Immune checkpoint inhibitors in NSCLC.

Authors: Johnson, Douglas B, Rioth, Matthew J, Horn, Leora

Year: 2014

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-014-0305-5

Paper Diabetic ketoacidosis shortly after COVID-19 vaccination in a non-small-cell lung cancer patient receiving combination of PD-1 and CTLA-4 inhibitors: A case report.

Makiguchi, Tomonori, Fukushima, Takashi, Tanaka, Hisashi, Taima, Kageaki, Takayasu, Shinobu, Tasaka, Sadatomo · 2022 · Thoracic cancer · DOI

Full title: Diabetic ketoacidosis shortly after COVID-19 vaccination in a non-small-cell lung cancer patient receiving combination of PD-1 and CTLA-4 inhibitors: A case report.

Authors: Makiguchi, Tomonori, Fukushima, Takashi, Tanaka, Hisashi, Taima, Kageaki, Takayasu, Shinobu, Tasaka, Sadatomo

Year: 2022

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.14352

Paper Current status and advances of immunotherapy in nasopharyngeal carcinoma.

Xu, Jian-Ying, Wei, Xiao-Li, Wang, Yi-Qin, Wang, Feng-Hua · 2022 · Therapeutic advances in medical oncology · DOI

Full title: Current status and advances of immunotherapy in nasopharyngeal carcinoma.

Authors: Xu, Jian-Ying, Wei, Xiao-Li, Wang, Yi-Qin, Wang, Feng-Hua

Year: 2022

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359221096214

Paper The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants.

Thangavelu, Govindarajan, Murphy, Kenneth M, Yagita, Hideo, Boon, Louis, Anderson, Colin C · 2011 · Immunobiology · DOI

Full title: The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants.

Authors: Thangavelu, Govindarajan, Murphy, Kenneth M, Yagita, Hideo, Boon, Louis, Anderson, Colin C

Year: 2011

Venue: Immunobiology

DOI: https://doi.org/10.1016/j.imbio.2011.01.007

Paper HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.

V. Naranbhai, Mathias Viard, M. Dean, S. Groha, D. Braun, C. Labaki, S. Shukla, Y. Yuki, Parantu K. Shah, K. Chin, M. Wind-Rotolo, X. Mu, P. Robbins, A. Gusev, T. Choueiri, J. Gulley, M. Carrington · 2021 · The Lancet Oncology · DOI

Full title: HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.

Authors: V. Naranbhai, Mathias Viard, M. Dean, S. Groha, D. Braun, C. Labaki, S. Shukla, Y. Yuki, Parantu K. Shah, K. Chin, M. Wind-Rotolo, X. Mu, P. Robbins, A. Gusev, T. Choueiri, J. Gulley, M. Carrington

Year: 2021

Venue: The Lancet Oncology

DOI: https://doi.org/10.1016/s1470-2045(21)00582-9

Paper Mathematical Modelling and Optimization of Medication Regimens for Combination Immunotherapy of Breast Cancer.

Xiong, Zixiao, Xia, Yunfei, Xue, Ling, Lei, Jinzhi · 2025 · Bulletin of mathematical biology · DOI

Full title: Mathematical Modelling and Optimization of Medication Regimens for Combination Immunotherapy of Breast Cancer.

Authors: Xiong, Zixiao, Xia, Yunfei, Xue, Ling, Lei, Jinzhi

Year: 2025

Venue: Bulletin of mathematical biology

DOI: https://doi.org/10.1007/s11538-025-01459-5

Paper Management of metastatic cutaneous melanoma: updates in clinical practice.

Schvartsman, Gustavo, Taranto, Patricia, Glitza, Isabella C, Agarwala, Sanjiv S, Atkins, Michael B, Buzaid, Antonio C · 2019 · Therapeutic advances in medical oncology · DOI

Full title: Management of metastatic cutaneous melanoma: updates in clinical practice.

Authors: Schvartsman, Gustavo, Taranto, Patricia, Glitza, Isabella C, Agarwala, Sanjiv S, Atkins, Michael B, Buzaid, Antonio C

Year: 2019

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/1758835919851663

Paper Neoadjuvant immune checkpoint inhibitors for patients with resectable stage III/IV melanoma: a nationwide real-life study in France (NEOMEL).

Nardin, Charlée, Cavalieri, Charlotte, Lebbé, Céleste, Gérard, Emilie, Puyraveau, Marc, Vergara, Rémi, Maubec, Eve, Kramkimel, Nora, Lesage, Candice, Rouanet, Jacques, Bonniaud, Bertille, Puzenat, Eve, Popescu, Dragos, Baroudjian, Barouyr, Le Corre, Yannick, Saiag, Philippe, Brunet-Possenti, Florence, Saint-Jean, Mélanie, Montaudié, Henri, Amini-Adle, Mona, Belkaïd, Samy, Grange, Florent, Mansard, Sandrine, Béjar, Claudia-Luisa, Darras, Sophie, Pagès, Cécile, Tournier, Emilie, Funck-Brentano, Elisa, Aubin, Francois · 2026 · The British journal of dermatology · DOI

Full title: Neoadjuvant immune checkpoint inhibitors for patients with resectable stage III/IV melanoma: a nationwide real-life study in France (NEOMEL).

Authors: Nardin, Charlée, Cavalieri, Charlotte, Lebbé, Céleste, Gérard, Emilie, Puyraveau, Marc, Vergara, Rémi, Maubec, Eve, Kramkimel, Nora, Lesage, Candice, Rouanet, Jacques, Bonniaud, Bertille, Puzenat, Eve, Popescu, Dragos, Baroudjian, Barouyr, Le Corre, Yannick, Saiag, Philippe, Brunet-Possenti, Florence, Saint-Jean, Mélanie, Montaudié, Henri, Amini-Adle, Mona, Belkaïd, Samy, Grange, Florent, Mansard, Sandrine, Béjar, Claudia-Luisa, Darras, Sophie, Pagès, Cécile, Tournier, Emilie, Funck-Brentano, Elisa, Aubin, Francois

Year: 2026

Venue: The British journal of dermatology

DOI: https://doi.org/10.1093/bjd/ljaf268

Paper AdAPT-001, an oncolytic adenovirus armed with a TGF-β trap, overcomes in vivo resistance to PD-L1-immunotherapy.

Larson, Christopher, Oronsky, Bryan, Reid, Tony · 2022 · American journal of cancer research

Full title: AdAPT-001, an oncolytic adenovirus armed with a TGF-β trap, overcomes in vivo resistance to PD-L1-immunotherapy.

Authors: Larson, Christopher, Oronsky, Bryan, Reid, Tony

Year: 2022

Venue: American journal of cancer research

Paper Systemic therapy for Asian patients with advanced BRAF V600-mutant melanoma in a real-world setting: A multi-center retrospective study in Japan (B-CHECK-RWD study).

Namikawa, Kenjiro, Ito, Takamichi, Yoshikawa, Shusuke, Yoshino, Koji, Kiniwa, Yukiko, Ohe, Shuichi, Isei, Taiki, Takenouchi, Tatsuya, Kato, Hiroshi, Mizuhashi, Satoru, Fukushima, Satoshi, Yamamoto, Yosuke, Inozume, Takashi, Fujisawa, Yasuhiro, Yamasaki, Osamu, Nakamura, Yasuhiro, Asai, Jun, Maekawa, Takeo, Funakoshi, Takeru, Matsushita, Shigeto, Nakano, Eiji, Oashi, Kohei, Kato, Junji, Uhara, Hisashi, Miyagawa, Takuya, Uchi, Hiroshi, Hatta, Naohito, Tsutsui, Keita, Maeda, Taku, Matsuya, Taisuke, Yanagisawa, Hiroto, Muto, Ikko, Okumura, Mao, Ogata, Dai, Yamazaki, Naoya · 2023 · Cancer medicine · DOI

Full title: Systemic therapy for Asian patients with advanced BRAF V600-mutant melanoma in a real-world setting: A multi-center retrospective study in Japan (B-CHECK-RWD study).

Authors: Namikawa, Kenjiro, Ito, Takamichi, Yoshikawa, Shusuke, Yoshino, Koji, Kiniwa, Yukiko, Ohe, Shuichi, Isei, Taiki, Takenouchi, Tatsuya, Kato, Hiroshi, Mizuhashi, Satoru, Fukushima, Satoshi, Yamamoto, Yosuke, Inozume, Takashi, Fujisawa, Yasuhiro, Yamasaki, Osamu, Nakamura, Yasuhiro, Asai, Jun, Maekawa, Takeo, Funakoshi, Takeru, Matsushita, Shigeto, Nakano, Eiji, Oashi, Kohei, Kato, Junji, Uhara, Hisashi, Miyagawa, Takuya, Uchi, Hiroshi, Hatta, Naohito, Tsutsui, Keita, Maeda, Taku, Matsuya, Taisuke, Yanagisawa, Hiroto, Muto, Ikko, Okumura, Mao, Ogata, Dai, Yamazaki, Naoya

Year: 2023

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.6438

Paper Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung Carcinoma Brain Metastases Receiving Immunotherapy.

Hulsbergen, Alexander F C, Mammi, Marco, Nagtegaal, Steven H J, Lak, Asad M, Kavouridis, Vasileios, Smith, Timothy R, Iorgulescu, Julian B, Mekary, Rania A, Verhoeff, Joost J C, Broekman, Marike L D, Phillips, John G · 2020 · International journal of radiation oncology, biology, physics · DOI

Full title: Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung Carcinoma Brain Metastases Receiving Immunotherapy.

Authors: Hulsbergen, Alexander F C, Mammi, Marco, Nagtegaal, Steven H J, Lak, Asad M, Kavouridis, Vasileios, Smith, Timothy R, Iorgulescu, Julian B, Mekary, Rania A, Verhoeff, Joost J C, Broekman, Marike L D, Phillips, John G

Year: 2020

Venue: International journal of radiation oncology, biology, physics

DOI: https://doi.org/10.1016/j.ijrobp.2020.04.018

Paper A multicenter randomized phase II study of nivolumab in combination with gemcitabine/cisplatin or ipilimumab as first-line therapy for patients with advanced unresectable biliary tract cancer (BilT-01).

Sahai, Vaibhav, Griffith, Kent A., Beg, Muhammad Shaalan, Shaib, Walid L., Mahalingam, Devalingam, Zhen, David B., Deming, Dustin A., Dey, Sumi, Mendiratta‐Lala, Mishal, Zalupski, Mark M. · 2020 · Journal of Clinical Oncology · DOI

Full title: A multicenter randomized phase II study of nivolumab in combination with gemcitabine/cisplatin or ipilimumab as first-line therapy for patients with advanced unresectable biliary tract cancer (BilT-01).

Authors: Sahai, Vaibhav, Griffith, Kent A., Beg, Muhammad Shaalan, Shaib, Walid L., Mahalingam, Devalingam, Zhen, David B., Deming, Dustin A., Dey, Sumi, Mendiratta‐Lala, Mishal, Zalupski, Mark M.

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.4582

Paper Predictive value of PD-L1 expression in response to immune checkpoint inhibitors for gastric cancer treatment: a systematic review and meta-analysis.

Noori, Maryam, Fayyaz, Farimah, Zali, Mohammad Reza, Bashash, Davood · 2023 · Expert review of anticancer therapy · DOI

Full title: Predictive value of PD-L1 expression in response to immune checkpoint inhibitors for gastric cancer treatment: a systematic review and meta-analysis.

Authors: Noori, Maryam, Fayyaz, Farimah, Zali, Mohammad Reza, Bashash, Davood

Year: 2023

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2023.2238896

Paper The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?

Shin, Daniel Sanghoon, Ribas, Antoni · 2015 · Current opinion in immunology · DOI

Full title: The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?

Authors: Shin, Daniel Sanghoon, Ribas, Antoni

Year: 2015

Venue: Current opinion in immunology

DOI: https://doi.org/10.1016/j.coi.2015.01.006

Paper Monotherapeutically nonactive CTLA-4 blockade results in greatly enhanced antitumor effects when combined with tumor-targeted superantigens in a B16 melanoma model.

Sundstedt, Anette, Celander, Mona, Eriksson, Helena, Törngren, Marie, Hedlund, Gunnar · 2012 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Monotherapeutically nonactive CTLA-4 blockade results in greatly enhanced antitumor effects when combined with tumor-targeted superantigens in a B16 melanoma model.

Authors: Sundstedt, Anette, Celander, Mona, Eriksson, Helena, Törngren, Marie, Hedlund, Gunnar

Year: 2012

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0b013e318253ec25

Paper Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!

Maio, Michele, Blank, Christian, Necchi, Andrea, Di Giacomo, Anna Maria, Ibrahim, Ramy, Lahn, Michael, Fox, Bernard A, Bell, R Bryan, Tortora, Giampaolo, Eggermont, Alexander M M · 2021 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!

Authors: Maio, Michele, Blank, Christian, Necchi, Andrea, Di Giacomo, Anna Maria, Ibrahim, Ramy, Lahn, Michael, Fox, Bernard A, Bell, R Bryan, Tortora, Giampaolo, Eggermont, Alexander M M

Year: 2021

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2021.04.035

Paper Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.

Chang, Hwai Wen, Frey, Gerhard, Liu, Haizhen, Xing, Charles, Steinman, Lawrence, Boyle, William J, Short, Jay M · 2021 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.

Authors: Chang, Hwai Wen, Frey, Gerhard, Liu, Haizhen, Xing, Charles, Steinman, Lawrence, Boyle, William J, Short, Jay M

Year: 2021

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2020606118

Paper Expert opinion on immunotherapy induced diabetes.

Smati, Sarra, Buffier, Perrine, Bouillet, Benjamin, Archambeaud, Françoise, Vergès, Bruno, Cariou, Bertrand · 2018 · Annales d'endocrinologie · DOI

Full title: Expert opinion on immunotherapy induced diabetes.

Authors: Smati, Sarra, Buffier, Perrine, Bouillet, Benjamin, Archambeaud, Françoise, Vergès, Bruno, Cariou, Bertrand

Year: 2018

Venue: Annales d'endocrinologie

DOI: https://doi.org/10.1016/j.ando.2018.07.006

Paper Role of Immunotherapy in the Management of Locally Advanced and Recurrent/Metastatic Cervical Cancer.

Dyer, Brandon A, Zamarin, Dmitriy, Eskandar, Ramez N, Mayadev, Jyoti M · 2019 · Journal of the National Comprehensive Cancer Network : JNCCN · DOI

Full title: Role of Immunotherapy in the Management of Locally Advanced and Recurrent/Metastatic Cervical Cancer.

Authors: Dyer, Brandon A, Zamarin, Dmitriy, Eskandar, Ramez N, Mayadev, Jyoti M

Year: 2019

Venue: Journal of the National Comprehensive Cancer Network : JNCCN

DOI: https://doi.org/10.6004/jnccn.2018.7108

Paper Sarcoidosis Following Anti-PD-1 and Anti-CTLA-4 Therapy for Metastatic Melanoma.

Reddy, Swathi B, Possick, Jennifer D, Kluger, Harriet M, Galan, Anjela, Han, Dale · 2017 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Sarcoidosis Following Anti-PD-1 and Anti-CTLA-4 Therapy for Metastatic Melanoma.

Authors: Reddy, Swathi B, Possick, Jennifer D, Kluger, Harriet M, Galan, Anjela, Han, Dale

Year: 2017

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000181

Paper New Clinical Approaches and Emerging Evidence on Immune-Checkpoint Inhibitors as Anti-Cancer Therapeutics: CTLA-4 and PD-1 Pathways and Beyond.

Christodoulou, Maria-Ioanna, Zaravinos, Apostolos · 2019 · Critical reviews in immunology · DOI

Full title: New Clinical Approaches and Emerging Evidence on Immune-Checkpoint Inhibitors as Anti-Cancer Therapeutics: CTLA-4 and PD-1 Pathways and Beyond.

Authors: Christodoulou, Maria-Ioanna, Zaravinos, Apostolos

Year: 2019

Venue: Critical reviews in immunology

DOI: https://doi.org/10.1615/CritRevImmunol.2020033340

Paper First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high metastatic colorectal cancer.

Nasca, Vincenzo, Tinè, Gabriele, Taieb, Julien, Lonardi, Sara, Boursi, Ben, Margalit, Ofer, Salvatore, Lisa, Cohen, Romain, Ros, Javier, Ambrosini, Margherita, Zwart, Koen, Roodhart, Jeanine, Jayachandran, Priya, Overman, Michael J, Elez, Maria Elena, Cremolini, Chiara, Tougeron, David, Koopman, Miriam, André, Thierry, Miceli, Rosalba, Pietrantonio, Filippo · 2025 · The oncologist · DOI

Full title: First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high metastatic colorectal cancer.

Authors: Nasca, Vincenzo, Tinè, Gabriele, Taieb, Julien, Lonardi, Sara, Boursi, Ben, Margalit, Ofer, Salvatore, Lisa, Cohen, Romain, Ros, Javier, Ambrosini, Margherita, Zwart, Koen, Roodhart, Jeanine, Jayachandran, Priya, Overman, Michael J, Elez, Maria Elena, Cremolini, Chiara, Tougeron, David, Koopman, Miriam, André, Thierry, Miceli, Rosalba, Pietrantonio, Filippo

Year: 2025

Venue: The oncologist

DOI: https://doi.org/10.1093/oncolo/oyaf255

Paper Anti-CTLA-4 m2a Antibody Exacerbates Cardiac Injury in Experimental Autoimmune Myocarditis Mice By Promoting Ccl5-Neutrophil Infiltration.

Wu, Ming-Ming, Yang, Yan-Chao, Cai, Yong-Xu, Jiang, Shuai, Xiao, Han, Miao, Chang, Jin, Xi-Yun, Sun, Yu, Bi, Xin, Hong, Zi, Zhu, Di, Yu, Miao, Mao, Jian-Jun, Yu, Chang-Jiang, Liang, Chen, Tang, Liang-Liang, Wang, Qiu-Shi, Shao, Qun, Jiang, Qing-Hua, Pan, Zhen-Wei, Zhang, Zhi-Ren · 2024 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: Anti-CTLA-4 m2a Antibody Exacerbates Cardiac Injury in Experimental Autoimmune Myocarditis Mice By Promoting Ccl5-Neutrophil Infiltration.

Authors: Wu, Ming-Ming, Yang, Yan-Chao, Cai, Yong-Xu, Jiang, Shuai, Xiao, Han, Miao, Chang, Jin, Xi-Yun, Sun, Yu, Bi, Xin, Hong, Zi, Zhu, Di, Yu, Miao, Mao, Jian-Jun, Yu, Chang-Jiang, Liang, Chen, Tang, Liang-Liang, Wang, Qiu-Shi, Shao, Qun, Jiang, Qing-Hua, Pan, Zhen-Wei, Zhang, Zhi-Ren

Year: 2024

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202400486

Paper Immune checkpoint blockade in melanoma: Advantages, shortcomings and emerging roles of the nanoparticles.

Mahdavi Gorabi, Armita, Sadat Ravari, Mehrnaz, Sanaei, Mohammad-Javad, Davaran, Soodabeh, Kesharwani, Prashant, Sahebkar, Amirhossein · 2022 · International immunopharmacology · DOI

Full title: Immune checkpoint blockade in melanoma: Advantages, shortcomings and emerging roles of the nanoparticles.

Authors: Mahdavi Gorabi, Armita, Sadat Ravari, Mehrnaz, Sanaei, Mohammad-Javad, Davaran, Soodabeh, Kesharwani, Prashant, Sahebkar, Amirhossein

Year: 2022

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2022.109300

Paper PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors.

Beyrend, Guillaume, van der Gracht, Esmé, Yilmaz, Ayse, van Duikeren, Suzanne, Camps, Marcel, Höllt, Thomas, Vilanova, Anna, van Unen, Vincent, Koning, Frits, de Miranda, Noel F C C, Arens, Ramon, Ossendorp, Ferry · 2019 · Journal for immunotherapy of cancer · DOI

Full title: PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors.

Authors: Beyrend, Guillaume, van der Gracht, Esmé, Yilmaz, Ayse, van Duikeren, Suzanne, Camps, Marcel, Höllt, Thomas, Vilanova, Anna, van Unen, Vincent, Koning, Frits, de Miranda, Noel F C C, Arens, Ramon, Ossendorp, Ferry

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0700-3

Paper Dose-dependent effect of anti-CTLA-4 on survival in sepsis.

Inoue, Shigeaki, Bo, Lulong, Bian, Jinjun, Unsinger, Jacqueline, Chang, Katherine, Hotchkiss, Richard S · 2011 · Shock (Augusta, Ga.) · DOI

Full title: Dose-dependent effect of anti-CTLA-4 on survival in sepsis.

Authors: Inoue, Shigeaki, Bo, Lulong, Bian, Jinjun, Unsinger, Jacqueline, Chang, Katherine, Hotchkiss, Richard S

Year: 2011

Venue: Shock (Augusta, Ga.)

DOI: https://doi.org/10.1097/SHK.0b013e3182168cce

Paper Heterogeneity and the tumor microenvironment in neuroendocrine prostate cancer

Brady, Lauren, Nelson, Peter S. · 2022 · Journal of Endocrinology · DOI

Full title: Heterogeneity and the tumor microenvironment in neuroendocrine prostate cancer

Authors: Brady, Lauren, Nelson, Peter S.

Year: 2022

Venue: Journal of Endocrinology

DOI: https://doi.org/10.1530/joe-22-0211

Paper Clinical utility of tumor mutational burden in patients with non-small cell lung cancer treated with immunotherapy

Hendriks, Lizza, Rouleau, Étienne, Besse, Benjamin · 2018 · Translational Lung Cancer Research · DOI

Full title: Clinical utility of tumor mutational burden in patients with non-small cell lung cancer treated with immunotherapy

Authors: Hendriks, Lizza, Rouleau, Étienne, Besse, Benjamin

Year: 2018

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2018.09.22

Paper Combinatory Immunotherapy for Glioblastoma Treatment

Muhammad Ijaz, Ikram Hasan, Zhiruo Jiang, Zia Ullah, B. Aslam, M. Khurshid, Yansun Sun, B. Guo · 2024 · Advances in Therapy · DOI

Full title: Combinatory Immunotherapy for Glioblastoma Treatment

Authors: Muhammad Ijaz, Ikram Hasan, Zhiruo Jiang, Zia Ullah, B. Aslam, M. Khurshid, Yansun Sun, B. Guo

Year: 2024

Venue: Advances in Therapy

DOI: https://doi.org/10.1002/adtp.202400217

Paper An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy.

Yang, Yuefeng, Xu, Weidong, Peng, Di, Wang, Hao, Zhang, Xiaoyan, Wang, Hua, Xiao, Fengjun, Zhu, Yitan, Ji, Yuan, Gulukota, Kamalakar, Helseth, Donald L, Mangold, Kathy A, Sullivan, Megan, Kaul, Karen, Wang, Edward, Prabhakar, Bellur S, Li, Jinnan, Wu, Xuejie, Wang, Lisheng, Seth, Prem · 2019 · Human gene therapy · DOI

Full title: An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy.

Authors: Yang, Yuefeng, Xu, Weidong, Peng, Di, Wang, Hao, Zhang, Xiaoyan, Wang, Hua, Xiao, Fengjun, Zhu, Yitan, Ji, Yuan, Gulukota, Kamalakar, Helseth, Donald L, Mangold, Kathy A, Sullivan, Megan, Kaul, Karen, Wang, Edward, Prabhakar, Bellur S, Li, Jinnan, Wu, Xuejie, Wang, Lisheng, Seth, Prem

Year: 2019

Venue: Human gene therapy

DOI: https://doi.org/10.1089/hum.2019.059

Paper Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor treatment: An observational study.

Basak, Edwin A, Vermeer, Niels S, de Joode, Karlijn, Hurkmans, Daan P, Velthuis, Dorian E M, Oomen-de Hoop, Esther, Schreurs, Marco W J, Bins, Sander, Koolen, Stijn L W, Debets, Reno, van der Veldt, Astrid A M, Aerts, Joachim G J V, Joosse, Arjen, Mathijssen, Ron H J · 2022 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor treatment: An observational study.

Authors: Basak, Edwin A, Vermeer, Niels S, de Joode, Karlijn, Hurkmans, Daan P, Velthuis, Dorian E M, Oomen-de Hoop, Esther, Schreurs, Marco W J, Bins, Sander, Koolen, Stijn L W, Debets, Reno, van der Veldt, Astrid A M, Aerts, Joachim G J V, Joosse, Arjen, Mathijssen, Ron H J

Year: 2022

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2022.07.015

Paper [Immune combination possibilities in the first-line treatment of metastatic renal cell cancer].

Küronya, Zsófia, Biró, Krisztina, Géczi, Lajos, Maráz, Anikó · 2023 · Magyar onkologia

Full title: [Immune combination possibilities in the first-line treatment of metastatic renal cell cancer].

Authors: Küronya, Zsófia, Biró, Krisztina, Géczi, Lajos, Maráz, Anikó

Year: 2023

Venue: Magyar onkologia

Paper Tumor microenvironment changes leading to resistance of immune checkpoint inhibitors in metastatic melanoma and strategies to overcome resistance.

Pulluri, Bhargavi, Kumar, Abhijeet, Shaheen, Montaser, Jeter, Joanne, Sundararajan, Srinath · 2017 · Pharmacological research · DOI

Full title: Tumor microenvironment changes leading to resistance of immune checkpoint inhibitors in metastatic melanoma and strategies to overcome resistance.

Authors: Pulluri, Bhargavi, Kumar, Abhijeet, Shaheen, Montaser, Jeter, Joanne, Sundararajan, Srinath

Year: 2017

Venue: Pharmacological research

DOI: https://doi.org/10.1016/j.phrs.2017.07.006

Paper Immunotherapy in Melanoma: Highlights for the General Practitioner.

Ben Aïssa, Assma · 2023 · Praxis · DOI

Full title: Immunotherapy in Melanoma: Highlights for the General Practitioner.

Authors: Ben Aïssa, Assma

Year: 2023

Venue: Praxis

DOI: https://doi.org/10.1024/1661-8157/a003972

Paper Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: engage, expand, enable, and evolve

Fabian, Kellsye P., Padget, Michelle R., Fujii, Rika, Schlom, Jeffrey, Hodge, James W. · 2021 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: engage, expand, enable, and evolve

Authors: Fabian, Kellsye P., Padget, Michelle R., Fujii, Rika, Schlom, Jeffrey, Hodge, James W.

Year: 2021

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2020-001691

Paper Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapy.

Liu, Mingyue, Wang, Xu, Du, Xuexiang, Wu, Wei, Zhang, Yan, Zhang, Peng, Ai, Chunxia, Devenport, Martin, Su, Juanjuan, Muthana, Musleh M, Su, Lishan, Liu, Yang, Zheng, Pan · 2023 · Science translational medicine · DOI

Full title: Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapy.

Authors: Liu, Mingyue, Wang, Xu, Du, Xuexiang, Wu, Wei, Zhang, Yan, Zhang, Peng, Ai, Chunxia, Devenport, Martin, Su, Juanjuan, Muthana, Musleh M, Su, Lishan, Liu, Yang, Zheng, Pan

Year: 2023

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.abm5663

Paper Eosinophil may be a predictor of immune-related adverse events induced by different immune checkpoint inhibitor types: A retrospective multidisciplinary study.

Tasaki, Yoshihiko, Sugiyama, Yosuke, Hamamoto, Shuzo, Naiki, Taku, Uemura, Takehiro, Yokota, Keisuke, Kawakita, Daisuke, Nakamura, Motoki, Ogawa, Ryo, Shimura, Takaya, Mimura, Yoshihisa, Hotta, Yuji, Odagiri, Kunihiro, Ito, Nanami, Iida, Moeko, Kimura, Yuka, Komatsu, Hirokazu, Kataoka, Hiromi, Takiguchi, Shuji, Morita, Akimichi, Iwasaki, Shinichi, Okuda, Katsuhiro, Niimi, Akio, Yasui, Takahiro, Furukawa-Hibi, Yoko · 2023 · Cancer medicine · DOI

Full title: Eosinophil may be a predictor of immune-related adverse events induced by different immune checkpoint inhibitor types: A retrospective multidisciplinary study.

Authors: Tasaki, Yoshihiko, Sugiyama, Yosuke, Hamamoto, Shuzo, Naiki, Taku, Uemura, Takehiro, Yokota, Keisuke, Kawakita, Daisuke, Nakamura, Motoki, Ogawa, Ryo, Shimura, Takaya, Mimura, Yoshihisa, Hotta, Yuji, Odagiri, Kunihiro, Ito, Nanami, Iida, Moeko, Kimura, Yuka, Komatsu, Hirokazu, Kataoka, Hiromi, Takiguchi, Shuji, Morita, Akimichi, Iwasaki, Shinichi, Okuda, Katsuhiro, Niimi, Akio, Yasui, Takahiro, Furukawa-Hibi, Yoko

Year: 2023

Venue: Cancer medicine

DOI: https://doi.org/10.1002/cam4.6724

Paper Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced cervical cancer: Cohort data from a phase 1b trial.

Liu, Jihong, Liu, Naifu, Wang, Danbo, Li, Dapeng, Fang, Cheng · 2022 · Journal of Clinical Oncology · DOI

Full title: Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced cervical cancer: Cohort data from a phase 1b trial.

Authors: Liu, Jihong, Liu, Naifu, Wang, Danbo, Li, Dapeng, Fang, Cheng

Year: 2022

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2022.40.16_suppl.5535

Paper Abstract 4491: Association of intratumoral immunologic profile with overall survival in metastatic pancreatic cancer patients treated with combination immunotherapy with or without PD-1 blockade

Wu, Annie A., Tsujikawa, Takahiro, Choe, Gina, Beechwood, Teresa, Coussens, Lisa M., Durham, Jennifer N., Jaffee, Elizabeth M., Le, Dung T. · 2019 · Immunology · DOI

Full title: Abstract 4491: Association of intratumoral immunologic profile with overall survival in metastatic pancreatic cancer patients treated with combination immunotherapy with or without PD-1 blockade

Authors: Wu, Annie A., Tsujikawa, Takahiro, Choe, Gina, Beechwood, Teresa, Coussens, Lisa M., Durham, Jennifer N., Jaffee, Elizabeth M., Le, Dung T.

Year: 2019

Venue: Immunology

DOI: https://doi.org/10.1158/1538-7445.sabcs18-4491

Paper Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui · 2020 · OncoTargets and therapy · DOI

Full title: Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Authors: Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui

Year: 2020

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S235714

Paper First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting by the Italian Association of Thoracic Oncology

Gridelli, Cesare, Peters, Solange, Mok, Tony, Forde, Patrick M., Reck, Martin, Attili, Ilaria, Marinis, Filippo de · 2021 · ESMO Open · DOI

Full title: First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting by the Italian Association of Thoracic Oncology

Authors: Gridelli, Cesare, Peters, Solange, Mok, Tony, Forde, Patrick M., Reck, Martin, Attili, Ilaria, Marinis, Filippo de

Year: 2021

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2021.100355

Paper Combining conventional therapy with immunotherapy: A risky business?

Coosemans, A, Vankerckhoven, A, Baert, T, Boon, L, Ruts, H, Riva, M, Blagden, S, Delforge, M, Concin, N, Mirza, M R, Ledermann, J A, du Bois, A, Vergote, I · 2019 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Combining conventional therapy with immunotherapy: A risky business?

Authors: Coosemans, A, Vankerckhoven, A, Baert, T, Boon, L, Ruts, H, Riva, M, Blagden, S, Delforge, M, Concin, N, Mirza, M R, Ledermann, J A, du Bois, A, Vergote, I

Year: 2019

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2019.02.014

Paper Quantification of immune response after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.

Kamp, William M., Park, Hong‐Jai, Slovak, Ryan, Ludwig, Johannes, Kang, Insoo, Kim, Hyun S. · 2020 · Journal of Clinical Oncology · DOI

Full title: Quantification of immune response after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.

Authors: Kamp, William M., Park, Hong‐Jai, Slovak, Ryan, Ludwig, Johannes, Kang, Insoo, Kim, Hyun S.

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.4_suppl.160

Paper Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and synergizes with CTLA-4 or TIM-3 blockade.

Ju, Fei, Luo, Yong, Lin, Chaolong, Jia, Xian, Xu, Zilong, Tian, Rui, Lin, Yanhua, Zhao, Min, Chang, Yating, Huang, Xiaoxuan, Li, Shaopeng, Ren, Wenfeng, Qin, Yaning, Yu, Mengqin, Jia, Jizong, Han, Jinle, Luo, Wenxin, Zhang, Jun, Fu, Guo, Ye, Xiangzhong, Huang, Chenghao, Xia, Ningshao · 2022 · Journal for immunotherapy of cancer · DOI

Full title: Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and synergizes with CTLA-4 or TIM-3 blockade.

Authors: Ju, Fei, Luo, Yong, Lin, Chaolong, Jia, Xian, Xu, Zilong, Tian, Rui, Lin, Yanhua, Zhao, Min, Chang, Yating, Huang, Xiaoxuan, Li, Shaopeng, Ren, Wenfeng, Qin, Yaning, Yu, Mengqin, Jia, Jizong, Han, Jinle, Luo, Wenxin, Zhang, Jun, Fu, Guo, Ye, Xiangzhong, Huang, Chenghao, Xia, Ningshao

Year: 2022

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2022-004762

Paper High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection

Catherine Rexhouse, Jacob T. Bailey, S. Moshkani, Jesse L. Cimino, M. Robek · 2025 · Journal of Virology · DOI

Full title: High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection

Authors: Catherine Rexhouse, Jacob T. Bailey, S. Moshkani, Jesse L. Cimino, M. Robek

Year: 2025

Venue: Journal of Virology

DOI: https://doi.org/10.1128/jvi.00711-25

Paper Liver immunotolerance and hepatocellular carcinoma: Patho-physiological mechanisms and therapeutic perspectives.

Roth, Gaël S, Decaens, Thomas · 2017 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Liver immunotolerance and hepatocellular carcinoma: Patho-physiological mechanisms and therapeutic perspectives.

Authors: Roth, Gaël S, Decaens, Thomas

Year: 2017

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2017.10.010

Paper CTLA-4 blockade expands infiltrating T cells and inhibits cancer cell repopulation during the intervals of chemotherapy in murine mesothelioma.

Wu, Licun, Yun, Zhihong, Tagawa, Tetsuzo, Rey-McIntyre, Katrina, de Perrot, Marc · 2012 · Molecular cancer therapeutics · DOI

Full title: CTLA-4 blockade expands infiltrating T cells and inhibits cancer cell repopulation during the intervals of chemotherapy in murine mesothelioma.

Authors: Wu, Licun, Yun, Zhihong, Tagawa, Tetsuzo, Rey-McIntyre, Katrina, de Perrot, Marc

Year: 2012

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-11-1014

Paper Immune Checkpoint Inhibitors in Locally Advanced, Unresectable, and Metastatic Upper Gastrointestinal Malignancies.

Katz, Heather, Biglow, Layana, Alsharedi, Mohamed · 2020 · Journal of gastrointestinal cancer · DOI

Full title: Immune Checkpoint Inhibitors in Locally Advanced, Unresectable, and Metastatic Upper Gastrointestinal Malignancies.

Authors: Katz, Heather, Biglow, Layana, Alsharedi, Mohamed

Year: 2020

Venue: Journal of gastrointestinal cancer

DOI: https://doi.org/10.1007/s12029-019-00243-8

Paper Subcutaneous inoculation position affects the immune environment in CT26 carcinomas.

Fu, Xiaocong, Yang, Yeguo, Xie, Jinling, Pan, Xianglong, Yang, Xue, Du, Zhengcai, Hao, Erwei · 2019 · Biochemical and biophysical research communications · DOI

Full title: Subcutaneous inoculation position affects the immune environment in CT26 carcinomas.

Authors: Fu, Xiaocong, Yang, Yeguo, Xie, Jinling, Pan, Xianglong, Yang, Xue, Du, Zhengcai, Hao, Erwei

Year: 2019

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2019.03.042

Paper Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer.

Dorta-Estremera, Stephanie, Hegde, Venkatesh L, Slay, Ravaen B, Sun, Rachel, Yanamandra, Ananta V, Nicholas, Courtney, Nookala, Sita, Sierra, Gloria, Curran, Michael A, Sastry, K Jagannadha · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer.

Authors: Dorta-Estremera, Stephanie, Hegde, Venkatesh L, Slay, Ravaen B, Sun, Rachel, Yanamandra, Ananta V, Nicholas, Courtney, Nookala, Sita, Sierra, Gloria, Curran, Michael A, Sastry, K Jagannadha

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0728-4

Paper Myocarditis, Myositis, and Myasthenia Gravis: The Complexities of Treating Steroid-Refractory Triple M Syndrome.

Halloran, Sean, Patel, Ruchi, Tilkens, Blair, Alban, Juan, Zubenko, Alexandra, Mohindra, Nisha, Lomasney, Jon, Akhter, Nausheen · 2025 · JACC. Case reports · DOI

Full title: Myocarditis, Myositis, and Myasthenia Gravis: The Complexities of Treating Steroid-Refractory Triple M Syndrome.

Authors: Halloran, Sean, Patel, Ruchi, Tilkens, Blair, Alban, Juan, Zubenko, Alexandra, Mohindra, Nisha, Lomasney, Jon, Akhter, Nausheen

Year: 2025

Venue: JACC. Case reports

DOI: https://doi.org/10.1016/j.jaccas.2025.104188

Paper Multiple autoimmune side effects of immune checkpoint inhibitors in a patient with metastatic melanoma receiving pembrolizumab.

Kethireddy, Nikhila, Thomas, Steffi, Bindal, Poorva, Shukla, Prateek, Hegde, Upendra · 2021 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · DOI

Full title: Multiple autoimmune side effects of immune checkpoint inhibitors in a patient with metastatic melanoma receiving pembrolizumab.

Authors: Kethireddy, Nikhila, Thomas, Steffi, Bindal, Poorva, Shukla, Prateek, Hegde, Upendra

Year: 2021

Venue: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

DOI: https://doi.org/10.1177/1078155220921543

Paper A combination of lymphatic drug delivery of anti-CTLA-4 antibody and local radiotherapy for solid-tumor treatment.

Takagi, Koki, Sukhbaatar, Ariunbuyan, Inaba, Yohei, Mori, Shiro, Kodama, Tetsuya · 2024 · Cancer science · DOI

Full title: A combination of lymphatic drug delivery of anti-CTLA-4 antibody and local radiotherapy for solid-tumor treatment.

Authors: Takagi, Koki, Sukhbaatar, Ariunbuyan, Inaba, Yohei, Mori, Shiro, Kodama, Tetsuya

Year: 2024

Venue: Cancer science

DOI: https://doi.org/10.1111/cas.16369

Paper First-line immune-checkpoint inhibitor treatment in extensive-disease small-cell lung cancer: A classical and network meta-analysis.

Mutlu, Hasan, Bozcuk, Hakan, Artaç, Mehmet, Eser, İrfan · 2023 · Journal of cancer research and therapeutics · DOI

Full title: First-line immune-checkpoint inhibitor treatment in extensive-disease small-cell lung cancer: A classical and network meta-analysis.

Authors: Mutlu, Hasan, Bozcuk, Hakan, Artaç, Mehmet, Eser, İrfan

Year: 2023

Venue: Journal of cancer research and therapeutics

DOI: https://doi.org/10.4103/jcrt.jcrt_721_21

Paper Immune Checkpoint Inhibitors-Related Cardiotoxicity.

Konala, Venu Madhav, Adapa, Sreedhar, Aronow, Wilbert S · 2020 · American journal of therapeutics · DOI

Full title: Immune Checkpoint Inhibitors-Related Cardiotoxicity.

Authors: Konala, Venu Madhav, Adapa, Sreedhar, Aronow, Wilbert S

Year: 2020

Venue: American journal of therapeutics

DOI: https://doi.org/10.1097/MJT.0000000000000988

Paper Efficacy and safety of anti-PD-1/PD-L1 in combination with chemotherapy or not as first-line treatment for advanced non-small cell lung cancer: A systematic review and network meta-analysis.

Wang, Liming, Yang, Yifan, Yu, Jiangyong, Zhang, Shuai, Li, Xu, Wu, Xiaonan, Nie, Xin, Liu, Wenbo, Zhang, Ping, Li, Yi, Li, Ailing, Ai, Bin · 2022 · Thoracic cancer · DOI

Full title: Efficacy and safety of anti-PD-1/PD-L1 in combination with chemotherapy or not as first-line treatment for advanced non-small cell lung cancer: A systematic review and network meta-analysis.

Authors: Wang, Liming, Yang, Yifan, Yu, Jiangyong, Zhang, Shuai, Li, Xu, Wu, Xiaonan, Nie, Xin, Liu, Wenbo, Zhang, Ping, Li, Yi, Li, Ailing, Ai, Bin

Year: 2022

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.14244

Paper Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab.

Graziani, Grazia, Lisi, Lucia, Tentori, Lucio, Navarra, Pierluigi · 2022 · Experientia supplementum (2012) · DOI

Full title: Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab.

Authors: Graziani, Grazia, Lisi, Lucia, Tentori, Lucio, Navarra, Pierluigi

Year: 2022

Venue: Experientia supplementum (2012)

DOI: https://doi.org/10.1007/978-3-030-91311-3_10

Paper Emerging Nonsurgical Therapies for Locally Advanced and Metastatic Nonmelanoma Skin Cancer

Leon Chen, Alexander B Aria, Sirunya Silapunt, M. Migden · 2019 · Dermatologic Surgery · DOI

Full title: Emerging Nonsurgical Therapies for Locally Advanced and Metastatic Nonmelanoma Skin Cancer

Authors: Leon Chen, Alexander B Aria, Sirunya Silapunt, M. Migden

Year: 2019

Venue: Dermatologic Surgery

DOI: https://doi.org/10.1097/dss.0000000000001601

Paper CTLA-4 and PD-L1 checkpoint blockade enhances oncolytic measles virus therapy.

Engeland, Christine E, Grossardt, Christian, Veinalde, Rūta, Bossow, Sascha, Lutz, Diana, Kaufmann, Johanna K, Shevchenko, Ivan, Umansky, Viktor, Nettelbeck, Dirk M, Weichert, Wilko, Jäger, Dirk, von Kalle, Christof, Ungerechts, Guy · 2014 · Molecular therapy : the journal of the American Society of Gene Therapy · DOI

Full title: CTLA-4 and PD-L1 checkpoint blockade enhances oncolytic measles virus therapy.

Authors: Engeland, Christine E, Grossardt, Christian, Veinalde, Rūta, Bossow, Sascha, Lutz, Diana, Kaufmann, Johanna K, Shevchenko, Ivan, Umansky, Viktor, Nettelbeck, Dirk M, Weichert, Wilko, Jäger, Dirk, von Kalle, Christof, Ungerechts, Guy

Year: 2014

Venue: Molecular therapy : the journal of the American Society of Gene Therapy

DOI: https://doi.org/10.1038/mt.2014.160

Paper Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab.

Hober, Candice, Jamme, Philippe, Desmedt, Eve, Greliak, Anna, Mortier, Laurent · 2021 · Therapeutic advances in medical oncology · DOI

Full title: Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab.

Authors: Hober, Candice, Jamme, Philippe, Desmedt, Eve, Greliak, Anna, Mortier, Laurent

Year: 2021

Venue: Therapeutic advances in medical oncology

DOI: https://doi.org/10.1177/17588359211015493

Paper Intracranial Control with Combined Dual Immune-Checkpoint Blockade and SRS for Melanoma and NSCLC Brain Metastases

Vaios, Eugene, Shenker, R.F., Hendrickson, P., Wan, Zhe, Niedzwiecki, D., Winter, S.F., Dietrich, Jörg, Salama, April K.S., Clarke, Jeffrey, Allen, K.J., Mullikin, Trey C., Floyd, Scott, Kirkpatrick, J.P., Reitman, Zachary J. · 2023 · International Journal of Radiation Oncology*Biology*Physics · DOI

Full title: Intracranial Control with Combined Dual Immune-Checkpoint Blockade and SRS for Melanoma and NSCLC Brain Metastases

Authors: Vaios, Eugene, Shenker, R.F., Hendrickson, P., Wan, Zhe, Niedzwiecki, D., Winter, S.F., Dietrich, Jörg, Salama, April K.S., Clarke, Jeffrey, Allen, K.J., Mullikin, Trey C., Floyd, Scott, Kirkpatrick, J.P., Reitman, Zachary J.

Year: 2023

Venue: International Journal of Radiation Oncology*Biology*Physics

DOI: https://doi.org/10.1016/j.ijrobp.2023.06.637

Paper Enterocolitis due to immune checkpoint inhibitors: a systematic review.

Soularue, Emilie, Lepage, Patricia, Colombel, Jean Frederic, Coutzac, Clelia, Faleck, David, Marthey, Lysiane, Collins, Michael, Chaput, Nathalie, Robert, Caroline, Carbonnel, Franck · 2018 · Gut · DOI

Full title: Enterocolitis due to immune checkpoint inhibitors: a systematic review.

Authors: Soularue, Emilie, Lepage, Patricia, Colombel, Jean Frederic, Coutzac, Clelia, Faleck, David, Marthey, Lysiane, Collins, Michael, Chaput, Nathalie, Robert, Caroline, Carbonnel, Franck

Year: 2018

Venue: Gut

DOI: https://doi.org/10.1136/gutjnl-2018-316948

Paper Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model.

Zheng, Fang, Dang, Jianzhong, Zhang, Hongyu, Xu, Fangzhou, Ba, Diandian, Zhang, Bingyu, Cheng, Fanjun, Chang, Alfred E, Wicha, Max S, Li, Qiao · 2018 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model.

Authors: Zheng, Fang, Dang, Jianzhong, Zhang, Hongyu, Xu, Fangzhou, Ba, Diandian, Zhang, Bingyu, Cheng, Fanjun, Chang, Alfred E, Wicha, Max S, Li, Qiao

Year: 2018

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000242

Paper The efficacy of combination immunotherapy with ipilimumab plus nivolumab in metastatic myxofibrosarcoma.

Kalofonou, Foteini, Napolitano, Andrea, Benson, Charlotte, Miah, Aisha, Zaidi, Shane, Lindsay, Daniel, Thway, Khin, Jones, Robin L · 2024 · Rare tumors · DOI

Full title: The efficacy of combination immunotherapy with ipilimumab plus nivolumab in metastatic myxofibrosarcoma.

Authors: Kalofonou, Foteini, Napolitano, Andrea, Benson, Charlotte, Miah, Aisha, Zaidi, Shane, Lindsay, Daniel, Thway, Khin, Jones, Robin L

Year: 2024

Venue: Rare tumors

DOI: https://doi.org/10.1177/20363613241290788

Paper Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer.

Crespo-Rodriguez, Eva, Bergerhoff, Katharina, Bozhanova, Galabina, Foo, Shane, Patin, Emmanuel C, Whittock, Harriet, Buus, Richard, Haider, Syed, Muirhead, Gareth, Thway, Khin, Newbold, Kate, Coffin, Robert S, Vile, Richard G, Kim, Dae, McLaughlin, Martin, Melcher, Alan A, Harrington, Kevin J, Pedersen, Malin · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer.

Authors: Crespo-Rodriguez, Eva, Bergerhoff, Katharina, Bozhanova, Galabina, Foo, Shane, Patin, Emmanuel C, Whittock, Harriet, Buus, Richard, Haider, Syed, Muirhead, Gareth, Thway, Khin, Newbold, Kate, Coffin, Robert S, Vile, Richard G, Kim, Dae, McLaughlin, Martin, Melcher, Alan A, Harrington, Kevin J, Pedersen, Malin

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-000698

Paper Curing tumor-bearing mice by shifting a Th2 to a Th1 anti-tumor response.

Hellstrom, Karl Erik, Dai, Min, Hellstrom, Ingegerd · 2017 · Human antibodies · DOI

Full title: Curing tumor-bearing mice by shifting a Th2 to a Th1 anti-tumor response.

Authors: Hellstrom, Karl Erik, Dai, Min, Hellstrom, Ingegerd

Year: 2017

Venue: Human antibodies

DOI: https://doi.org/10.3233/HAB-160309

Paper Severe thromboembolic phenomenon in the setting of pseudoprogression of melanoma brain metastases in response to combination immunotherapy

M. Perez, H. Yu, J. Markowitz · 2018 · BMJ Case Reports · DOI

Full title: Severe thromboembolic phenomenon in the setting of pseudoprogression of melanoma brain metastases in response to combination immunotherapy

Authors: M. Perez, H. Yu, J. Markowitz

Year: 2018

Venue: BMJ Case Reports

DOI: https://doi.org/10.1136/bcr-2018-226089

Paper Encouraging specific biomarkers-based therapeutic strategies for hepatocellular carcinoma.

Yao, Min, Yang, Jun-Ling, Wang, De-Feng, Wang, Li, Chen, Ying, Yao, Deng-Fu · 2022 · World journal of clinical cases · DOI

Full title: Encouraging specific biomarkers-based therapeutic strategies for hepatocellular carcinoma.

Authors: Yao, Min, Yang, Jun-Ling, Wang, De-Feng, Wang, Li, Chen, Ying, Yao, Deng-Fu

Year: 2022

Venue: World journal of clinical cases

DOI: https://doi.org/10.12998/wjcc.v10.i11.3321

Paper Cutaneous adverse events in lung cancer patients on the therapy based on PD-1/PD-L1 inhibitors: A prospective observational cohort study.

Dang, Yong-Chao, Kong, Qing-Tao, Wang, Zhen, Sang, Hong · 2023 · Current problems in cancer · DOI

Full title: Cutaneous adverse events in lung cancer patients on the therapy based on PD-1/PD-L1 inhibitors: A prospective observational cohort study.

Authors: Dang, Yong-Chao, Kong, Qing-Tao, Wang, Zhen, Sang, Hong

Year: 2023

Venue: Current problems in cancer

DOI: https://doi.org/10.1016/j.currproblcancer.2022.100934

Paper Checkpoint inhibitors (CPI) and autoimmune chronic inflammatory diseases (ACIDs): tolerance and loss of tolerance in the occurrence of immuno-rheumatologic manifestations.

Gremese, Elisa, Alivernini, Stefano, Ferraccioli, Edoardo Sean, Ferraccioli, Gianfranco · 2020 · Clinical immunology (Orlando, Fla.) · DOI

Full title: Checkpoint inhibitors (CPI) and autoimmune chronic inflammatory diseases (ACIDs): tolerance and loss of tolerance in the occurrence of immuno-rheumatologic manifestations.

Authors: Gremese, Elisa, Alivernini, Stefano, Ferraccioli, Edoardo Sean, Ferraccioli, Gianfranco

Year: 2020

Venue: Clinical immunology (Orlando, Fla.)

DOI: https://doi.org/10.1016/j.clim.2020.108395

Paper Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade.

Mitsuhashi, Atsushi, Koyama, Kazuya, Ogino, Hirokazu, Afroj, Tania, Nguyen, Na Thi, Yoneda, Hiroto, Otsuka, Kenji, Sugimoto, Masamichi, Kondoh, Osamu, Nokihara, Hiroshi, Hanibuchi, Masaki, Takizawa, Hiromitsu, Shinohara, Tsutomu, Nishioka, Yasuhiko · 2023 · Cell reports · DOI

Full title: Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade.

Authors: Mitsuhashi, Atsushi, Koyama, Kazuya, Ogino, Hirokazu, Afroj, Tania, Nguyen, Na Thi, Yoneda, Hiroto, Otsuka, Kenji, Sugimoto, Masamichi, Kondoh, Osamu, Nokihara, Hiroshi, Hanibuchi, Masaki, Takizawa, Hiromitsu, Shinohara, Tsutomu, Nishioka, Yasuhiko

Year: 2023

Venue: Cell reports

DOI: https://doi.org/10.1016/j.celrep.2023.112162

Paper Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma.

Shirinbak, Soheila, Chan, Randall Y, Shahani, Shilpa, Muthugounder, Sakunthala, Kennedy, Rebekah, Hung, Long T, Fernandez, G Esteban, Hadjidaniel, Michael D, Moghimi, Babak, Sheard, Michael A, Epstein, Alan L, Fabbri, Muller, Shimada, Hiroyuki, Asgharzadeh, Shahab · 2021 · Oncoimmunology · DOI

Full title: Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma.

Authors: Shirinbak, Soheila, Chan, Randall Y, Shahani, Shilpa, Muthugounder, Sakunthala, Kennedy, Rebekah, Hung, Long T, Fernandez, G Esteban, Hadjidaniel, Michael D, Moghimi, Babak, Sheard, Michael A, Epstein, Alan L, Fabbri, Muller, Shimada, Hiroyuki, Asgharzadeh, Shahab

Year: 2021

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2020.1838140

Paper Personalized Therapy of Small Cell Lung Cancer.

Schneider, Bryan J, Kalemkerian, Gregory P · 2016 · Advances in experimental medicine and biology · DOI

Full title: Personalized Therapy of Small Cell Lung Cancer.

Authors: Schneider, Bryan J, Kalemkerian, Gregory P

Year: 2016

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-319-24932-2_9

Paper Meta-analysis of the efficacy and safety of PD-1/PD-L1 inhibitors administered alone or in combination with anti-VEGF agents in advanced hepatocellular carcinoma.

Feng, Zhichao, Rong, Pengfei, Wang, Wei · 2020 · Gut · DOI

Full title: Meta-analysis of the efficacy and safety of PD-1/PD-L1 inhibitors administered alone or in combination with anti-VEGF agents in advanced hepatocellular carcinoma.

Authors: Feng, Zhichao, Rong, Pengfei, Wang, Wei

Year: 2020

Venue: Gut

DOI: https://doi.org/10.1136/gutjnl-2019-320116

Paper Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists.

Sitkovsky, Michail V, Hatfield, Stephen, Abbott, Robert, Belikoff, Bryan, Lukashev, Dmitriy, Ohta, Akio · 2014 · Cancer immunology research · DOI

Full title: Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists.

Authors: Sitkovsky, Michail V, Hatfield, Stephen, Abbott, Robert, Belikoff, Bryan, Lukashev, Dmitriy, Ohta, Akio

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0075

Paper Efficacy and safety of CTLA-4 inhibitors combined with PD-1 inhibitors or chemotherapy in patients with advanced melanoma.

Zhang, Bo, Zhou, You Lang, Chen, Xinming, Wang, Ziheng, Wang, Qiuhong, Ju, Fei, Ren, Shiqi, Xu, Ran, Xue, Qun, Wu, Qiong · 2019 · International immunopharmacology · DOI

Full title: Efficacy and safety of CTLA-4 inhibitors combined with PD-1 inhibitors or chemotherapy in patients with advanced melanoma.

Authors: Zhang, Bo, Zhou, You Lang, Chen, Xinming, Wang, Ziheng, Wang, Qiuhong, Ju, Fei, Ren, Shiqi, Xu, Ran, Xue, Qun, Wu, Qiong

Year: 2019

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2018.12.034

Paper Tumor Mutation Burden as a Potential Biomarker for PD-1/PD-L1 Inhibition in Advanced Non-small Cell Lung Cancer.

Huang, Di, Zhang, Fan, Tao, Haitao, Zhang, Sujie, Ma, Junxun, Wang, Jinliang, Liu, Zhefeng, Cui, Pengfei, Chen, Shixue, Huang, Ziwei, Wu, Zhaozhen, Zhao, Lei, Hu, Yi · 2020 · Targeted oncology · DOI

Full title: Tumor Mutation Burden as a Potential Biomarker for PD-1/PD-L1 Inhibition in Advanced Non-small Cell Lung Cancer.

Authors: Huang, Di, Zhang, Fan, Tao, Haitao, Zhang, Sujie, Ma, Junxun, Wang, Jinliang, Liu, Zhefeng, Cui, Pengfei, Chen, Shixue, Huang, Ziwei, Wu, Zhaozhen, Zhao, Lei, Hu, Yi

Year: 2020

Venue: Targeted oncology

DOI: https://doi.org/10.1007/s11523-020-00703-3

Paper TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.

Dougall, William C, Kurtulus, Sema, Smyth, Mark J, Anderson, Ana C · 2017 · Immunological reviews · DOI

Full title: TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.

Authors: Dougall, William C, Kurtulus, Sema, Smyth, Mark J, Anderson, Ana C

Year: 2017

Venue: Immunological reviews

DOI: https://doi.org/10.1111/imr.12518

Paper LILRB4 expression in chronic myelomonocytic leukemia and myelodysplastic syndrome based on response to hypomethylating agents.

Chien, Kelly S, Class, Caleb A, Montalban-Bravo, Guillermo, Wei, Yue, Sasaki, Koji, Naqvi, Kiran, Ganan-Gomez, Irene, Yang, Hui, Soltysiak, Kelly A, Kanagal-Shamanna, Rashmi, Do, Kim-Anh, Kantarjian, Hagop M, Garcia-Manero, Guillermo · 2020 · Leukemia & lymphoma · DOI

Full title: LILRB4 expression in chronic myelomonocytic leukemia and myelodysplastic syndrome based on response to hypomethylating agents.

Authors: Chien, Kelly S, Class, Caleb A, Montalban-Bravo, Guillermo, Wei, Yue, Sasaki, Koji, Naqvi, Kiran, Ganan-Gomez, Irene, Yang, Hui, Soltysiak, Kelly A, Kanagal-Shamanna, Rashmi, Do, Kim-Anh, Kantarjian, Hagop M, Garcia-Manero, Guillermo

Year: 2020

Venue: Leukemia & lymphoma

DOI: https://doi.org/10.1080/10428194.2020.1723014

Paper Association between CD8+ tumor-infiltrating lymphocytes and prognosis of non-small cell lung cancer patients treated with PD-1/PD-L1 inhibitors: a systematic review and meta-analysis.

Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Li, Guo-Xiang, Zhao, Meng-Meng, Sun, Zhi-Gang · 2023 · Expert review of anticancer therapy · DOI

Full title: Association between CD8+ tumor-infiltrating lymphocytes and prognosis of non-small cell lung cancer patients treated with PD-1/PD-L1 inhibitors: a systematic review and meta-analysis.

Authors: Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Li, Guo-Xiang, Zhao, Meng-Meng, Sun, Zhi-Gang

Year: 2023

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2023.2208351

Paper Anti-Tumor Efficacy of Anti-PD-1/PD-L1 Antibodies in Combination With Other Anticancer Drugs in Solid Tumors: A Systematic Review and Meta-Analysis.

Inoue, Takashi, Narukawa, Mamoru · 2022 · Cancer control : journal of the Moffitt Cancer Center · DOI

Full title: Anti-Tumor Efficacy of Anti-PD-1/PD-L1 Antibodies in Combination With Other Anticancer Drugs in Solid Tumors: A Systematic Review and Meta-Analysis.

Authors: Inoue, Takashi, Narukawa, Mamoru

Year: 2022

Venue: Cancer control : journal of the Moffitt Cancer Center

DOI: https://doi.org/10.1177/10732748221140694

Paper Evaluation of PD-L1 as a biomarker for immunotherapy for hepatocellular carcinoma: systematic review and meta-analysis.

Xu Zhou, Jiasheng Cao, Win Topatana, Tian-Ao Xie, Tian-Bin Chen, Jiahao Hu, Shijie Li, Sarun Juengpanic, Ziyi Lu, Bin Zhang, Kaitai Wang, Xu Feng, Jiliang Shen, Mingyu Chen · 2023 · Immunotherapy · DOI

Full title: Evaluation of PD-L1 as a biomarker for immunotherapy for hepatocellular carcinoma: systematic review and meta-analysis.

Authors: Xu Zhou, Jiasheng Cao, Win Topatana, Tian-Ao Xie, Tian-Bin Chen, Jiahao Hu, Shijie Li, Sarun Juengpanic, Ziyi Lu, Bin Zhang, Kaitai Wang, Xu Feng, Jiliang Shen, Mingyu Chen

Year: 2023

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2022-0168

Paper Development of Bell's Palsy After Treatment With Ipilimumab and Nivolumab for Metastatic Melanoma: A Case Report.

Zecchini, Julia M, Kim, Sara, Yum, Kendra, Friedlander, Philip · 2018 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Development of Bell's Palsy After Treatment With Ipilimumab and Nivolumab for Metastatic Melanoma: A Case Report.

Authors: Zecchini, Julia M, Kim, Sara, Yum, Kendra, Friedlander, Philip

Year: 2018

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000184

Paper Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine

Sato, Hiro, Jeggo, Penny A., Shibata, Atsushi · 2019 · Cancer Science · DOI

Full title: Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine

Authors: Sato, Hiro, Jeggo, Penny A., Shibata, Atsushi

Year: 2019

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.14197

Paper Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma

O’Reilly, Eileen M., Oh, Do‐Youn, Dhani, Neesha C., Renouf, Daniel J., Lee, Myung Ah, Sun, Weijing, Fisher, George A., Hezel, Aram F., Chang, Shao-Chun, Vlahovic, Gordana, Takahashi, Osamu, Yang, Yin, Fitts, David, Philip, Philip Agop · 2019 · JAMA Oncology · DOI

Full title: Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Authors: O’Reilly, Eileen M., Oh, Do‐Youn, Dhani, Neesha C., Renouf, Daniel J., Lee, Myung Ah, Sun, Weijing, Fisher, George A., Hezel, Aram F., Chang, Shao-Chun, Vlahovic, Gordana, Takahashi, Osamu, Yang, Yin, Fitts, David, Philip, Philip Agop

Year: 2019

Venue: JAMA Oncology

DOI: https://doi.org/10.1001/jamaoncol.2019.1588

Paper Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions.

Bauché, David, Mauze, Smita, Kochel, Christina, Grein, Jeff, Sawant, Anandi, Zybina, Yulia, Blumenschein, Wendy, Yang, Peng, Annamalai, Lakshmanan, Yearley, Jennifer H, Punnonen, Juha, Bowman, Edward P, Chackerian, Alissa, Laface, Drake · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions.

Authors: Bauché, David, Mauze, Smita, Kochel, Christina, Grein, Jeff, Sawant, Anandi, Zybina, Yulia, Blumenschein, Wendy, Yang, Peng, Annamalai, Lakshmanan, Yearley, Jennifer H, Punnonen, Juha, Bowman, Edward P, Chackerian, Alissa, Laface, Drake

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-001584

Paper The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4.

Liu, Li, Mayes, Patrick A, Eastman, Stephen, Shi, Hong, Yadavilli, Sapna, Zhang, Tianqian, Yang, Jingsong, Seestaller-Wehr, Laura, Zhang, Shu-Yun, Hopson, Chris, Tsvetkov, Lyuben, Jing, Junping, Zhang, Shu, Smothers, James, Hoos, Axel · 2015 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4.

Authors: Liu, Li, Mayes, Patrick A, Eastman, Stephen, Shi, Hong, Yadavilli, Sapna, Zhang, Tianqian, Yang, Jingsong, Seestaller-Wehr, Laura, Zhang, Shu-Yun, Hopson, Chris, Tsvetkov, Lyuben, Jing, Junping, Zhang, Shu, Smothers, James, Hoos, Axel

Year: 2015

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-14-2339

Paper Nivolumab Plus Ipilimumab in Non-Small-Cell Lung Cancer

Reck, Martin, Borghaei, Hossein, O’Byrne, Kenneth J. · 2019 · Future Oncology · DOI

Full title: Nivolumab Plus Ipilimumab in Non-Small-Cell Lung Cancer

Authors: Reck, Martin, Borghaei, Hossein, O’Byrne, Kenneth J.

Year: 2019

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2019-0031

Paper Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy.

Blake, Stephen J, Stannard, Kimberley, Liu, Jing, Allen, Stacey, Yong, Michelle C R, Mittal, Deepak, Aguilera, Amelia Roman, Miles, John J, Lutzky, Viviana P, de Andrade, Lucas Ferrari, Martinet, Ludovic, Colonna, Marco, Takeda, Kazuyoshi, Kühnel, Florian, Gurlevik, Engin, Bernhardt, Günter, Teng, Michele W L, Smyth, Mark J · 2016 · Cancer discovery · DOI

Full title: Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy.

Authors: Blake, Stephen J, Stannard, Kimberley, Liu, Jing, Allen, Stacey, Yong, Michelle C R, Mittal, Deepak, Aguilera, Amelia Roman, Miles, John J, Lutzky, Viviana P, de Andrade, Lucas Ferrari, Martinet, Ludovic, Colonna, Marco, Takeda, Kazuyoshi, Kühnel, Florian, Gurlevik, Engin, Bernhardt, Günter, Teng, Michele W L, Smyth, Mark J

Year: 2016

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-15-0944

Paper Targeting MARCO in combination with anti-CTLA-4 leads to enhanced melanoma regression and immune cell infiltration via macrophage reprogramming.

Takahashi, Hidenori, Perez-Villarroel, Patricio, Falahat, Rana, Mulé, James J · 2025 · Journal for immunotherapy of cancer · DOI

Full title: Targeting MARCO in combination with anti-CTLA-4 leads to enhanced melanoma regression and immune cell infiltration via macrophage reprogramming.

Authors: Takahashi, Hidenori, Perez-Villarroel, Patricio, Falahat, Rana, Mulé, James J

Year: 2025

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2024-011030

Paper PD-L1 Expression in Triple-Negative Breast Cancer

Mittendorf, Elizabeth A., Philips, Anne V., Meric‐Bernstam, Funda, Qiao, Na, Wu, Yun, Harrington, Susan M., Su, Xiaoping, Wang, Ying, González-Angulo, Ana M., Akçakanat, Argun, Chawla, Akhil, Curran, Michael A., Hwu, Patrick, Sharma, Padmanee, Litton, Jennifer K., Molldrem, Jeffrey J., Alatrash, Gheath · 2014 · Cancer Immunology Research · DOI

Full title: PD-L1 Expression in Triple-Negative Breast Cancer

Authors: Mittendorf, Elizabeth A., Philips, Anne V., Meric‐Bernstam, Funda, Qiao, Na, Wu, Yun, Harrington, Susan M., Su, Xiaoping, Wang, Ying, González-Angulo, Ana M., Akçakanat, Argun, Chawla, Akhil, Curran, Michael A., Hwu, Patrick, Sharma, Padmanee, Litton, Jennifer K., Molldrem, Jeffrey J., Alatrash, Gheath

Year: 2014

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-13-0127

Paper CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy.

Chen, Hong, Fu, Tihui, Suh, Woong-Kyung, Tsavachidou, Dimitra, Wen, Sijin, Gao, Jianjun, Ng Tang, Derek, He, Qiuming, Sun, Jingjing, Sharma, Padmanee · 2014 · Cancer immunology research · DOI

Full title: CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy.

Authors: Chen, Hong, Fu, Tihui, Suh, Woong-Kyung, Tsavachidou, Dimitra, Wen, Sijin, Gao, Jianjun, Ng Tang, Derek, He, Qiuming, Sun, Jingjing, Sharma, Padmanee

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0155

Paper Enhancing efficacy of therapeutic vaccinations by combination with other modalities.

Gulley, James L, Madan, Ravi A, Arlen, Philip M · 2007 · Vaccine · DOI

Full title: Enhancing efficacy of therapeutic vaccinations by combination with other modalities.

Authors: Gulley, James L, Madan, Ravi A, Arlen, Philip M

Year: 2007

Venue: Vaccine

DOI: https://doi.org/10.1016/j.vaccine.2007.04.091

Paper Intratumoral Administration of the Immunotherapeutic Combination Anti-ctla4, Anti-cd137 and Anti-ox40: Comparison to Systemic Administration, Peri-Draining Lymph Node Injection, and Cellular Vaccine in a Mouse Lymphoma Model

J. Hebb, Adriane R. Mosley, Felipe Vences Catalan, P. Ellmark, P. Norlén, D. Felsher · 2016 · DOI

Full title: Intratumoral Administration of the Immunotherapeutic Combination Anti-ctla4, Anti-cd137 and Anti-ox40: Comparison to Systemic Administration, Peri-Draining Lymph Node Injection, and Cellular Vaccine in a Mouse Lymphoma Model

Authors: J. Hebb, Adriane R. Mosley, Felipe Vences Catalan, P. Ellmark, P. Norlén, D. Felsher

Year: 2016

DOI: https://doi.org/10.1182/blood.v128.22.4172.4172

Paper Immune targeting in breast cancer.

Cimino‐Mathews, Ashley, Foote, Jeremy B., Emens, Leisha A. · 2015 · PubMed

Full title: Immune targeting in breast cancer.

Authors: Cimino‐Mathews, Ashley, Foote, Jeremy B., Emens, Leisha A.

Year: 2015

Venue: PubMed

Paper Temozolomide overcoming resistance to immune checkpoint inhibitors in relapsed/refractory metastatic melanoma? Insights from a single center series.

Dasanu, Constantin A, Plaxe, Steven C · 2025 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · DOI

Full title: Temozolomide overcoming resistance to immune checkpoint inhibitors in relapsed/refractory metastatic melanoma? Insights from a single center series.

Authors: Dasanu, Constantin A, Plaxe, Steven C

Year: 2025

Venue: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

DOI: https://doi.org/10.1177/10781552241302421

Paper Complete response with neoadjuvant avelumab in Merkel cell carcinoma - A case report.

Abdallah, Nadine, Nagasaka, Misako, Chowdhury, Tahmida, Raval, Kunil, Hotaling, Jeffrey, Sukari, Ammar · 2019 · Oral oncology · DOI

Full title: Complete response with neoadjuvant avelumab in Merkel cell carcinoma - A case report.

Authors: Abdallah, Nadine, Nagasaka, Misako, Chowdhury, Tahmida, Raval, Kunil, Hotaling, Jeffrey, Sukari, Ammar

Year: 2019

Venue: Oral oncology

DOI: https://doi.org/10.1016/j.oraloncology.2019.06.031

Paper Intratumoral DNA-based delivery of checkpoint-inhibiting antibodies and interleukin 12 triggers T cell infiltration and anti-tumor response.

Jacobs, Liesl, Yshii, Lidia, Junius, Steffie, Geukens, Nick, Liston, Adrian, Hollevoet, Kevin, Declerck, Paul · 2022 · Cancer gene therapy · DOI

Full title: Intratumoral DNA-based delivery of checkpoint-inhibiting antibodies and interleukin 12 triggers T cell infiltration and anti-tumor response.

Authors: Jacobs, Liesl, Yshii, Lidia, Junius, Steffie, Geukens, Nick, Liston, Adrian, Hollevoet, Kevin, Declerck, Paul

Year: 2022

Venue: Cancer gene therapy

DOI: https://doi.org/10.1038/s41417-021-00403-8

Paper PD-L1 expression and EGFR status in advanced non-small-cell lung cancer patients receiving PD-1/PD-L1 inhibitors: a meta-analysis.

Li, Jing, Gu, Jian · 2019 · Future oncology (London, England) · DOI

Full title: PD-L1 expression and EGFR status in advanced non-small-cell lung cancer patients receiving PD-1/PD-L1 inhibitors: a meta-analysis.

Authors: Li, Jing, Gu, Jian

Year: 2019

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2018-0639

Paper Atypical patterns of response and progression in the era of immunotherapy combinations.

Ferrara, Roberto, Matos, Ignacio · 2020 · Future oncology (London, England) · DOI

Full title: Atypical patterns of response and progression in the era of immunotherapy combinations.

Authors: Ferrara, Roberto, Matos, Ignacio

Year: 2020

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2020-0186

Paper From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy.

Osipov, Arsen, Murphy, Adrian, Zheng, Lei · 2019 · Advances in cancer research · DOI

Full title: From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy.

Authors: Osipov, Arsen, Murphy, Adrian, Zheng, Lei

Year: 2019

Venue: Advances in cancer research

DOI: https://doi.org/10.1016/bs.acr.2019.03.002

Paper [Immunotherapy as modern tumor treatment].

Grüllich, C · 2017 · Der Radiologe · DOI

Full title: [Immunotherapy as modern tumor treatment].

Authors: Grüllich, C

Year: 2017

Venue: Der Radiologe

DOI: https://doi.org/10.1007/s00117-017-0298-8

Paper Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial.

Ott, Patrick A, Nazzaro, Matthew, Pfaff, Kathleen L, Gjini, Evisa, Felt, Kristen D, Wolff, Jacquelyn O, Buchbinder, Elizabeth I, Haq, Rizwan, Sullivan, Ryan J, Lawrence, Donald P, McDermott, David F, Severgnini, Mariano, Giobbie-Hurder, Anita, Rodig, Scott J, Stephen Hodi, F · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial.

Authors: Ott, Patrick A, Nazzaro, Matthew, Pfaff, Kathleen L, Gjini, Evisa, Felt, Kristen D, Wolff, Jacquelyn O, Buchbinder, Elizabeth I, Haq, Rizwan, Sullivan, Ryan J, Lawrence, Donald P, McDermott, David F, Severgnini, Mariano, Giobbie-Hurder, Anita, Rodig, Scott J, Stephen Hodi, F

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2021-003318

Paper Data from Attenuation of sialylation augments antitumor immunity and improves response to immunotherapy in ovarian cancer

Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou · 2024 · DOI

Full title: Data from Attenuation of sialylation augments antitumor immunity and improves response to immunotherapy in ovarian cancer

Authors: Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou

Year: 2024

DOI: https://doi.org/10.1158/0008-5472.c.6711188.v3

Paper The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy.

Long, Long, Zhang, Xue, Chen, Fuchun, Pan, Qi, Phiphatwatchara, Pronnaphat, Zeng, Yuyang, Chen, Honglei · 2018 · Genes & cancer · DOI

Full title: The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy.

Authors: Long, Long, Zhang, Xue, Chen, Fuchun, Pan, Qi, Phiphatwatchara, Pronnaphat, Zeng, Yuyang, Chen, Honglei

Year: 2018

Venue: Genes & cancer

DOI: https://doi.org/10.18632/genesandcancer.180

Paper First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer

Horn, Leora, Mansfield, Aaron S., Szczęsna, Aleksandra, Havel, Libor, Krzakowski, Maciej, Hochmair, Maximilian J., Huemer, Florian, Losonczy, György, Johnson, Melissa L., Nishio, Makoto, Reck, Martin, Mok, Tony, Lam, Sivuonthanh, Shames, David S., Liu, Juan, Ding, Beiying, López-Chávez, Ariel, Kabbinavar, Fairooz F., Lin, Wei, Sandler, Alan, Liu, Stephen V. · 2018 · New England Journal of Medicine · DOI

Full title: First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer

Authors: Horn, Leora, Mansfield, Aaron S., Szczęsna, Aleksandra, Havel, Libor, Krzakowski, Maciej, Hochmair, Maximilian J., Huemer, Florian, Losonczy, György, Johnson, Melissa L., Nishio, Makoto, Reck, Martin, Mok, Tony, Lam, Sivuonthanh, Shames, David S., Liu, Juan, Ding, Beiying, López-Chávez, Ariel, Kabbinavar, Fairooz F., Lin, Wei, Sandler, Alan, Liu, Stephen V.

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1809064

Paper Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management

A. Muntyanu, E. Netchiporouk, W. Gerstein, R. Gniadecki, I. Litvinov · 2020 · Journal of Cutaneous Medicine and Surgery · DOI

Full title: Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management

Authors: A. Muntyanu, E. Netchiporouk, W. Gerstein, R. Gniadecki, I. Litvinov

Year: 2020

Venue: Journal of Cutaneous Medicine and Surgery

DOI: https://doi.org/10.1177/1203475420943260

Paper CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT

Noman, Muhammad Zaeem, Moer, Kris Van, Marani, Vanessa, Gemmill, Robert M., Tranchevent, Léon-Charles, Azuaje, Francisco, Muller, Arnaud, Chouaı̈b, Salem, Thiery, Jean Paul, Berchem, Guy, Janji, Bassam · 2017 · OncoImmunology · DOI

Full title: CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT

Authors: Noman, Muhammad Zaeem, Moer, Kris Van, Marani, Vanessa, Gemmill, Robert M., Tranchevent, Léon-Charles, Azuaje, Francisco, Muller, Arnaud, Chouaı̈b, Salem, Thiery, Jean Paul, Berchem, Guy, Janji, Bassam

Year: 2017

Venue: OncoImmunology

DOI: https://doi.org/10.1080/2162402x.2017.1345415

Paper Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma.

A. Tarhini, J. Cherian, S. Moschos, H. Tawbi, Yongli Shuai, W. Gooding, C. Sander, J. Kirkwood · 2012 · Journal of Clinical Oncology · DOI

Full title: Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma.

Authors: A. Tarhini, J. Cherian, S. Moschos, H. Tawbi, Yongli Shuai, W. Gooding, C. Sander, J. Kirkwood

Year: 2012

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2011.37.5394

Paper A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope.

Li, Dong, Li, Jing, Chu, Huanyu, Wang, Zhuozhi · 2020 · mAbs · DOI

Full title: A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope.

Authors: Li, Dong, Li, Jing, Chu, Huanyu, Wang, Zhuozhi

Year: 2020

Venue: mAbs

DOI: https://doi.org/10.1080/19420862.2020.1725365

Paper Combination immunotherapy with ipilimumab and nivolumab in patients with rare gynaecological malignancies.

Klein, Oliver, Kee, Damien, Gao, Bo, Markman, Ben, Mileshkin, Linda, Scott, Clare L., So, Yeojeong, Linklater, Richelle, Behren, Andreas, Palmer, Jodie, Carlino, Matteo S., Cebon, Jonathan · 2020 · Journal of Clinical Oncology · DOI

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with rare gynaecological malignancies.

Authors: Klein, Oliver, Kee, Damien, Gao, Bo, Markman, Ben, Mileshkin, Linda, Scott, Clare L., So, Yeojeong, Linklater, Richelle, Behren, Andreas, Palmer, Jodie, Carlino, Matteo S., Cebon, Jonathan

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.15_suppl.6091

Paper Dual CTLA-4 and PD-1 checkpoint blockade using CS1002 and CS1003 (nofazinlimab) in patients with advanced solid tumors: A first-in-human, dose-escalation, and dose-expansion study.

Bishnoi, Sarwan, Kotasek, Dusan, Aghmesheh, Morteza, Yau, Thomas, Cosman, Rasha, Prawira, Amy, Moore, Maggie, Chan, Stephen L, Mant, Andrew, Eek, Richard, Zielinski, Robert, Su, Rila, Pan, Zhaoxuan, Ma, Yiding, Li, Fei, Li, Peiqi, Tse, Archie N · 2024 · Cancer · DOI

Full title: Dual CTLA-4 and PD-1 checkpoint blockade using CS1002 and CS1003 (nofazinlimab) in patients with advanced solid tumors: A first-in-human, dose-escalation, and dose-expansion study.

Authors: Bishnoi, Sarwan, Kotasek, Dusan, Aghmesheh, Morteza, Yau, Thomas, Cosman, Rasha, Prawira, Amy, Moore, Maggie, Chan, Stephen L, Mant, Andrew, Eek, Richard, Zielinski, Robert, Su, Rila, Pan, Zhaoxuan, Ma, Yiding, Li, Fei, Li, Peiqi, Tse, Archie N

Year: 2024

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.35226

Paper 373 Dual immune checkpoint blockade enhances tumor-infiltrating lymphocyte expansion and survival in murine glioma models

Kuminkoski, Chloe R, Jackson, Sydney A, Stepniak, Amelia, Raphael, Itay, Chagantipati, Bhuvi, Kohanbash, Gary · 2025 · Regular and Young Investigator Award Abstracts · DOI

Full title: 373 Dual immune checkpoint blockade enhances tumor-infiltrating lymphocyte expansion and survival in murine glioma models

Authors: Kuminkoski, Chloe R, Jackson, Sydney A, Stepniak, Amelia, Raphael, Itay, Chagantipati, Bhuvi, Kohanbash, Gary

Year: 2025

Venue: Regular and Young Investigator Award Abstracts

DOI: https://doi.org/10.1136/jitc-2025-sitc2025.0373

Paper Predictors of Radiation Resistance and Novel Radiation Sensitizers in Head and Neck Cancers: Advancing Radiotherapy Efficacy.

Sobti, Aastha, Skinner, Heath, Wilke, Christopher T · 2025 · Seminars in radiation oncology · DOI

Full title: Predictors of Radiation Resistance and Novel Radiation Sensitizers in Head and Neck Cancers: Advancing Radiotherapy Efficacy.

Authors: Sobti, Aastha, Skinner, Heath, Wilke, Christopher T

Year: 2025

Venue: Seminars in radiation oncology

DOI: https://doi.org/10.1016/j.semradonc.2025.02.008

Paper Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model.

Kaumaya, Pravin T P, Guo, Linlin, Overholser, Jay, Penichet, Manuel L, Bekaii-Saab, Tanios · 2020 · Oncoimmunology · DOI

Full title: Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model.

Authors: Kaumaya, Pravin T P, Guo, Linlin, Overholser, Jay, Penichet, Manuel L, Bekaii-Saab, Tanios

Year: 2020

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2020.1818437

Paper CTLA-4: As an Immunosuppressive Immune Checkpoint in Breast Cancer.

Ghahremani Dehbokri, Shaho, Alizadeh, Nazila, Isazadeh, Alireza, Baghbanzadeh, Amir, Abbaspour-Ravasjani, Soheil, Hajiasgharzadeh, Khalil, Baradaran, Behzad · 2023 · Current molecular medicine · DOI

Full title: CTLA-4: As an Immunosuppressive Immune Checkpoint in Breast Cancer.

Authors: Ghahremani Dehbokri, Shaho, Alizadeh, Nazila, Isazadeh, Alireza, Baghbanzadeh, Amir, Abbaspour-Ravasjani, Soheil, Hajiasgharzadeh, Khalil, Baradaran, Behzad

Year: 2023

Venue: Current molecular medicine

DOI: https://doi.org/10.2174/1566524022666220610094716

Paper Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial.

Hong, David S, Postow, Michael, Chmielowski, Bartosz, Sullivan, Ryan, Patnaik, Amita, Cohen, Ezra E W, Shapiro, Geoffrey, Steuer, Conor, Gutierrez, Martin, Yeckes-Rodin, Heather, Ilaria, Robert, O'Connell, Brenda, Peng, Joanna, Peng, Guangbin, Zizlsperger, Nora, Tolcher, Anthony, Wolchok, Jedd D · 2023 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial.

Authors: Hong, David S, Postow, Michael, Chmielowski, Bartosz, Sullivan, Ryan, Patnaik, Amita, Cohen, Ezra E W, Shapiro, Geoffrey, Steuer, Conor, Gutierrez, Martin, Yeckes-Rodin, Heather, Ilaria, Robert, O'Connell, Brenda, Peng, Joanna, Peng, Guangbin, Zizlsperger, Nora, Tolcher, Anthony, Wolchok, Jedd D

Year: 2023

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-22-3313

Paper Toxicity patterns with immunomodulating antibodies and their combinations.

Haanen, John B A G, Thienen, Hans van, Blank, Christian U · 2015 · Seminars in oncology · DOI

Full title: Toxicity patterns with immunomodulating antibodies and their combinations.

Authors: Haanen, John B A G, Thienen, Hans van, Blank, Christian U

Year: 2015

Venue: Seminars in oncology

DOI: https://doi.org/10.1053/j.seminoncol.2015.02.011

Paper Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.

Messenheimer, David J, Jensen, Shawn M, Afentoulis, Michael E, Wegmann, Keith W, Feng, Zipei, Friedman, David J, Gough, Michael J, Urba, Walter J, Fox, Bernard A · 2017 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.

Authors: Messenheimer, David J, Jensen, Shawn M, Afentoulis, Michael E, Wegmann, Keith W, Feng, Zipei, Friedman, David J, Gough, Michael J, Urba, Walter J, Fox, Bernard A

Year: 2017

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-16-2677

Paper [Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs].

Gaultier De Saint Basile, Hortense, Poisson, Caroline, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Tartour, Eric, De Guillebon, Eléonore · 2018 · Bulletin du cancer · DOI

Full title: [Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs].

Authors: Gaultier De Saint Basile, Hortense, Poisson, Caroline, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Tartour, Eric, De Guillebon, Eléonore

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2018.10.004

Paper Immune checkpoint molecules in acute myeloid leukaemia: managing the double-edged sword.

Hobo, Willemijn, Hutten, Tim J A, Schaap, Nicolaas P M, Dolstra, Harry · 2018 · British journal of haematology · DOI

Full title: Immune checkpoint molecules in acute myeloid leukaemia: managing the double-edged sword.

Authors: Hobo, Willemijn, Hutten, Tim J A, Schaap, Nicolaas P M, Dolstra, Harry

Year: 2018

Venue: British journal of haematology

DOI: https://doi.org/10.1111/bjh.15078

Paper Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer.

Zhang, Wei, Shi, Long, Zhao, Zhilong, Du, Pingping, Ye, Xueshuai, Li, Dongbin, Cai, Zhenhua, Han, Jinsheng, Cai, Jianhui · 2019 · Cancer chemotherapy and pharmacology · DOI

Full title: Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer.

Authors: Zhang, Wei, Shi, Long, Zhao, Zhilong, Du, Pingping, Ye, Xueshuai, Li, Dongbin, Cai, Zhenhua, Han, Jinsheng, Cai, Jianhui

Year: 2019

Venue: Cancer chemotherapy and pharmacology

DOI: https://doi.org/10.1007/s00280-019-03800-x

Paper Abstract 4063: Single cell immune profiling of patients with advanced biliary cancers treated with combination checkpoint inhibition and GM-CSF reveals diverse T cell and myeloid cell mechanisms of action

Bridget P. Keenan, W. Tamaki, E. Liu, Brandon Chen, A. Cheung, J. Gordan, Brenna Sheldon, Li Zhang, R. Kelley, L. Fong · 2019 · Immunology · DOI

Full title: Abstract 4063: Single cell immune profiling of patients with advanced biliary cancers treated with combination checkpoint inhibition and GM-CSF reveals diverse T cell and myeloid cell mechanisms of action

Authors: Bridget P. Keenan, W. Tamaki, E. Liu, Brandon Chen, A. Cheung, J. Gordan, Brenna Sheldon, Li Zhang, R. Kelley, L. Fong

Year: 2019

Venue: Immunology

DOI: https://doi.org/10.1158/1538-7445.sabcs18-4063

Paper Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial

Zamarin, Dmitriy, Walderich, Sven, Holland, Aliya, Zhou, Qin, Iasonos, Alexia, Torrisi, Jean, Merghoub, Taha, Chesebrough, Lewis, Mcdonnell, Autumn S, Gallagher, Jacqueline M, Li, Yanyun, Hollmann, Travis J., Grisham, Rachel N., Erskine, Courtney L., Block, M.S., Knutson, Keith L., O’Cearbhaill, Roisin E., Aghajanian, Carol, Konner, Jason · 2020 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial

Authors: Zamarin, Dmitriy, Walderich, Sven, Holland, Aliya, Zhou, Qin, Iasonos, Alexia, Torrisi, Jean, Merghoub, Taha, Chesebrough, Lewis, Mcdonnell, Autumn S, Gallagher, Jacqueline M, Li, Yanyun, Hollmann, Travis J., Grisham, Rachel N., Erskine, Courtney L., Block, M.S., Knutson, Keith L., O’Cearbhaill, Roisin E., Aghajanian, Carol, Konner, Jason

Year: 2020

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2020-000829

Paper The impact of CDCA5 expression on the immune microenvironment and its potential utility as a biomarker for PD-L1/PD-1 inhibitors in lung adenocarcinoma.

Koh, Young Wha, Hwang, Yoonjung, Lee, Seul-Ki, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo · 2024 · Translational oncology · DOI

Full title: The impact of CDCA5 expression on the immune microenvironment and its potential utility as a biomarker for PD-L1/PD-1 inhibitors in lung adenocarcinoma.

Authors: Koh, Young Wha, Hwang, Yoonjung, Lee, Seul-Ki, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo

Year: 2024

Venue: Translational oncology

DOI: https://doi.org/10.1016/j.tranon.2024.102024

Paper PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy.

Zahm, Christopher D, Moseman, Jena E, Delmastro, Lauren E, G Mcneel, Douglas · 2021 · Oncoimmunology · DOI

Full title: PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy.

Authors: Zahm, Christopher D, Moseman, Jena E, Delmastro, Lauren E, G Mcneel, Douglas

Year: 2021

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2021.1912892

Paper Changes of peripheral T cell subsets in melanoma patients with immune-related adverse events.

Müller, Benjamin, Bärenwaldt, Anne, Herzig, Petra, Zippelius, Alfred, Maul, Lara Valeska, Hess, Viviane, König, David, Läubli, Heinz · 2023 · Frontiers in immunology · DOI

Full title: Changes of peripheral T cell subsets in melanoma patients with immune-related adverse events.

Authors: Müller, Benjamin, Bärenwaldt, Anne, Herzig, Petra, Zippelius, Alfred, Maul, Lara Valeska, Hess, Viviane, König, David, Läubli, Heinz

Year: 2023

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2023.1125111

Paper Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

Gangaev, Anastasia, Rozeman, Elisa A, Rohaan, Maartje W, Isaeva, Olga I, Philips, Daisy, Patiwael, Sanne, van den Berg, Joost H, Ribas, Antoni, Schadendorf, Dirk, Schilling, Bastian, Schumacher, Ton N, Blank, Christian U, Haanen, John B A G, Kvistborg, Pia · 2021 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

Authors: Gangaev, Anastasia, Rozeman, Elisa A, Rohaan, Maartje W, Isaeva, Olga I, Philips, Daisy, Patiwael, Sanne, van den Berg, Joost H, Ribas, Antoni, Schadendorf, Dirk, Schilling, Bastian, Schumacher, Ton N, Blank, Christian U, Haanen, John B A G, Kvistborg, Pia

Year: 2021

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.2102849118

Paper Emerging Role of Combination Immunotherapy in the First-line Treatment of Advanced Renal Cell Carcinoma

George, Saby, Rini, Brian I., Hammers, Hans J. · 2018 · JAMA Oncology · DOI

Full title: Emerging Role of Combination Immunotherapy in the First-line Treatment of Advanced Renal Cell Carcinoma

Authors: George, Saby, Rini, Brian I., Hammers, Hans J.

Year: 2018

Venue: JAMA Oncology

DOI: https://doi.org/10.1001/jamaoncol.2018.4604

Paper Immunotherapy in Advanced Lung Cancer.

Joy Huang, K. Reckamp · 2020 · Oncology · DOI

Full title: Immunotherapy in Advanced Lung Cancer.

Authors: Joy Huang, K. Reckamp

Year: 2020

Venue: Oncology

DOI: https://doi.org/10.46883/onc.2020.3407.0272

Paper Getting personal in metastatic melanoma: neoantigen-based vaccines as a new therapeutic strategy.

D'Alise, Anna Morena, Scarselli, Elisa · 2023 · Current opinion in oncology · DOI

Full title: Getting personal in metastatic melanoma: neoantigen-based vaccines as a new therapeutic strategy.

Authors: D'Alise, Anna Morena, Scarselli, Elisa

Year: 2023

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000923

Paper Nivolumab plus chemotherapy in first-line metastatic non-small-cell lung cancer: results of the phase III CheckMate 227 Part 2 trial

Borghaei, Hossein, O’Byrne, Kenneth J., Paz‐Ares, Luis, Ciuleanu, T-E., Yu, Xiaochu, Płużański, Adam, Nagrial, Adnan, Havel, Libor, Kowalyszyn, Rubén Dario, Audigier-Valette, Clarisse, Brahmer, Julie R., Reck, Martin, Ramalingam, S.S., Zhang, Li, Ntambwe, Ives, Rabindran, Sridhar K., Nathan, Faith E., Balli, David, Wu, Yi‐Long · 2023 · ESMO Open · DOI

Full title: Nivolumab plus chemotherapy in first-line metastatic non-small-cell lung cancer: results of the phase III CheckMate 227 Part 2 trial

Authors: Borghaei, Hossein, O’Byrne, Kenneth J., Paz‐Ares, Luis, Ciuleanu, T-E., Yu, Xiaochu, Płużański, Adam, Nagrial, Adnan, Havel, Libor, Kowalyszyn, Rubén Dario, Audigier-Valette, Clarisse, Brahmer, Julie R., Reck, Martin, Ramalingam, S.S., Zhang, Li, Ntambwe, Ives, Rabindran, Sridhar K., Nathan, Faith E., Balli, David, Wu, Yi‐Long

Year: 2023

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2023.102065

Paper Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy.

Landry, M R, DuRoss, A N, Neufeld, M J, Hahn, L, Sahay, G, Luxenhofer, R, Sun, C · 2020 · Materials today. Bio · DOI

Full title: Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy.

Authors: Landry, M R, DuRoss, A N, Neufeld, M J, Hahn, L, Sahay, G, Luxenhofer, R, Sun, C

Year: 2020

Venue: Materials today. Bio

DOI: https://doi.org/10.1016/j.mtbio.2020.100082

Paper Reviewer #1 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: Reviewer #1 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2023

DOI: https://doi.org/10.7554/elife.87292.1.sa2

Paper Efficacy of PD-1/PD-L1 inhibitors in patients with advanced non-small cell lung cancer: A meta-analysis of randomized clinical trials.

Peng, Tzu-Rong, Wu, Ta-Wei · 2019 · Thoracic cancer · DOI

Full title: Efficacy of PD-1/PD-L1 inhibitors in patients with advanced non-small cell lung cancer: A meta-analysis of randomized clinical trials.

Authors: Peng, Tzu-Rong, Wu, Ta-Wei

Year: 2019

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.13060

Paper Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4+ effector T cell infiltration into murine pancreatic tumors.

Zaidi, Neeha, Quezada, Sergio A, Kuroiwa, Janelle M Y, Zhang, Li, Jaffee, Elizabeth M, Steinman, Ralph M, Wang, Bei · 2019 · Annals of the New York Academy of Sciences · DOI

Full title: Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4+ effector T cell infiltration into murine pancreatic tumors.

Authors: Zaidi, Neeha, Quezada, Sergio A, Kuroiwa, Janelle M Y, Zhang, Li, Jaffee, Elizabeth M, Steinman, Ralph M, Wang, Bei

Year: 2019

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1111/nyas.14049

Paper Combination therapy with immune checkpoint inhibitors in advanced renal cell carcinoma: A meta-analysis of randomized controlled trials.

Mo, Dun-Chang, Huang, Jian-Feng, Luo, Peng-Hui, Huang, Shang-Xiao, Wang, Han-Lei · 2021 · Clinical immunology (Orlando, Fla.) · DOI

Full title: Combination therapy with immune checkpoint inhibitors in advanced renal cell carcinoma: A meta-analysis of randomized controlled trials.

Authors: Mo, Dun-Chang, Huang, Jian-Feng, Luo, Peng-Hui, Huang, Shang-Xiao, Wang, Han-Lei

Year: 2021

Venue: Clinical immunology (Orlando, Fla.)

DOI: https://doi.org/10.1016/j.clim.2021.108876

Paper Cardiotoxicity of immune checkpoint inhibitors.

Varricchi, Gilda, Galdiero, Maria Rosaria, Marone, Giancarlo, Criscuolo, Gjada, Triassi, Maria, Bonaduce, Domenico, Marone, Gianni, Tocchetti, Carlo Gabriele · 2017 · ESMO open · DOI

Full title: Cardiotoxicity of immune checkpoint inhibitors.

Authors: Varricchi, Gilda, Galdiero, Maria Rosaria, Marone, Giancarlo, Criscuolo, Gjada, Triassi, Maria, Bonaduce, Domenico, Marone, Gianni, Tocchetti, Carlo Gabriele

Year: 2017

Venue: ESMO open

DOI: https://doi.org/10.1136/esmoopen-2017-000247

Paper New insight in endocrine-related adverse events associated to immune checkpoint blockade.

Elia, Giusy, Ferrari, Silvia Martina, Galdiero, Maria Rosaria, Ragusa, Francesca, Paparo, Sabrina Rosaria, Ruffilli, Ilaria, Varricchi, Gilda, Fallahi, Poupak, Antonelli, Alessandro · 2020 · Best practice & research. Clinical endocrinology & metabolism · DOI

Full title: New insight in endocrine-related adverse events associated to immune checkpoint blockade.

Authors: Elia, Giusy, Ferrari, Silvia Martina, Galdiero, Maria Rosaria, Ragusa, Francesca, Paparo, Sabrina Rosaria, Ruffilli, Ilaria, Varricchi, Gilda, Fallahi, Poupak, Antonelli, Alessandro

Year: 2020

Venue: Best practice & research. Clinical endocrinology & metabolism

DOI: https://doi.org/10.1016/j.beem.2019.101370

Paper Neoadjuvant combination immunotherapy with ipilimumab (3 mg/kg or 10mg/kg) and high dose IFN-a2b in locally/regionally advanced melanoma.

Tarhini, Ahmad A., Rahman, Zahra, Lin, Yan, Vallabhaneni, Priyanka, Tawbi, Hussein, Gnan, Andrew, McFadden, Amanda, Rose, Amy, Pruckner, Chelsea, Wilson, Melissa, Pingpank, James F., Holtzman, Matthew P., Ferris, Robert L., Rao, Uma N. M., Kirkwood, John M. · 2016 · Journal of Clinical Oncology · DOI

Full title: Neoadjuvant combination immunotherapy with ipilimumab (3 mg/kg or 10mg/kg) and high dose IFN-a2b in locally/regionally advanced melanoma.

Authors: Tarhini, Ahmad A., Rahman, Zahra, Lin, Yan, Vallabhaneni, Priyanka, Tawbi, Hussein, Gnan, Andrew, McFadden, Amanda, Rose, Amy, Pruckner, Chelsea, Wilson, Melissa, Pingpank, James F., Holtzman, Matthew P., Ferris, Robert L., Rao, Uma N. M., Kirkwood, John M.

Year: 2016

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2016.34.15_suppl.9585

Paper Management of V600E and V600K BRAF-Mutant Melanoma.

Haugh, Alexandra M, Johnson, Douglas B · 2019 · Current treatment options in oncology · DOI

Full title: Management of V600E and V600K BRAF-Mutant Melanoma.

Authors: Haugh, Alexandra M, Johnson, Douglas B

Year: 2019

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-019-0680-z

Paper Emerging immunotherapies in ovarian cancer.

Ojalvo, Laureen S, Nichols, Paige E, Jelovac, Danijela, Emens, Leisha A · 2015 · Discovery medicine

Full title: Emerging immunotherapies in ovarian cancer.

Authors: Ojalvo, Laureen S, Nichols, Paige E, Jelovac, Danijela, Emens, Leisha A

Year: 2015

Venue: Discovery medicine

Paper Combination of bevacizumab and dual immunotherapy for extensive-disease small-cell lung cancer: a case report.

Lei Song, R. Zhou, Xiangyong Li, Dejian Pan · 2021 · Immunotherapy · DOI

Full title: Combination of bevacizumab and dual immunotherapy for extensive-disease small-cell lung cancer: a case report.

Authors: Lei Song, R. Zhou, Xiangyong Li, Dejian Pan

Year: 2021

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2021-0025

Paper Combination immunotherapy in genitourinary malignancies.

Hoffman-Censits, Jean, Wilde, Lindsay · 2016 · Current opinion in urology · DOI

Full title: Combination immunotherapy in genitourinary malignancies.

Authors: Hoffman-Censits, Jean, Wilde, Lindsay

Year: 2016

Venue: Current opinion in urology

DOI: https://doi.org/10.1097/MOU.0000000000000336

Paper Prognostic roles of hematological indicators in programmed cell death protein 1/programmed cell death ligand 1 inhibitors for small-cell lung cancer: a retrospective cohort study.

Du, Jiya, Zhang, Qian, Tian, Le, Chen, Yishan, Tian, Ye, Dempke, Wolfram C M, Arasanz, Hugo, Soo, Ross Andrew, Zhou, Zhiguo, Meng, Qingju, Liu, Yibing · 2024 · Journal of thoracic disease · DOI

Full title: Prognostic roles of hematological indicators in programmed cell death protein 1/programmed cell death ligand 1 inhibitors for small-cell lung cancer: a retrospective cohort study.

Authors: Du, Jiya, Zhang, Qian, Tian, Le, Chen, Yishan, Tian, Ye, Dempke, Wolfram C M, Arasanz, Hugo, Soo, Ross Andrew, Zhou, Zhiguo, Meng, Qingju, Liu, Yibing

Year: 2024

Venue: Journal of thoracic disease

DOI: https://doi.org/10.21037/jtd-24-1826

Paper Safety and efficacy of immune checkpoint blockade in patients with advanced nonsmall cell lung cancer and brain metastasis

Tsakonas, Georgios, Ekman, Simon, Koulouris, Andreas, Adderley, Helen, Ackermann, Christoph, Califano, Raffaele · 2023 · International Journal of Cancer · DOI

Full title: Safety and efficacy of immune checkpoint blockade in patients with advanced nonsmall cell lung cancer and brain metastasis

Authors: Tsakonas, Georgios, Ekman, Simon, Koulouris, Andreas, Adderley, Helen, Ackermann, Christoph, Califano, Raffaele

Year: 2023

Venue: International Journal of Cancer

DOI: https://doi.org/10.1002/ijc.34628

Paper Emerging Immunotargets and Immunotherapies in Prostate Cancer.

Montironi, Rodolfo, Santoni, Matteo, Sotte, Valeria, Cheng, Liang, Lopez-Beltran, Antonio, Massari, Francesco, Matrana, Marc R, Moch, Holger, Berardi, Rossana, Scarpelli, Marina · 2016 · Current drug targets · DOI

Full title: Emerging Immunotargets and Immunotherapies in Prostate Cancer.

Authors: Montironi, Rodolfo, Santoni, Matteo, Sotte, Valeria, Cheng, Liang, Lopez-Beltran, Antonio, Massari, Francesco, Matrana, Marc R, Moch, Holger, Berardi, Rossana, Scarpelli, Marina

Year: 2016

Venue: Current drug targets

DOI: https://doi.org/10.2174/1389450117666160217123304

Paper Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model.

Reardon, David A, Gokhale, Prafulla C, Klein, Sarah R, Ligon, Keith L, Rodig, Scott J, Ramkissoon, Shakti H, Jones, Kristen L, Conway, Amy Saur, Liao, Xiaoyun, Zhou, Jun, Wen, Patrick Y, Van Den Abbeele, Annick D, Hodi, F Stephen, Qin, Lei, Kohl, Nancy E, Sharpe, Arlene H, Dranoff, Glenn, Freeman, Gordon J · 2016 · Cancer immunology research · DOI

Full title: Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model.

Authors: Reardon, David A, Gokhale, Prafulla C, Klein, Sarah R, Ligon, Keith L, Rodig, Scott J, Ramkissoon, Shakti H, Jones, Kristen L, Conway, Amy Saur, Liao, Xiaoyun, Zhou, Jun, Wen, Patrick Y, Van Den Abbeele, Annick D, Hodi, F Stephen, Qin, Lei, Kohl, Nancy E, Sharpe, Arlene H, Dranoff, Glenn, Freeman, Gordon J

Year: 2016

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-15-0151

Paper Personalized precision combination therapies based on potential actionability and coalterations and therapeutic opportunities for CDK12-mutated prostate cancer.

Hong Li, Haitao Wang · 2023 · Journal of Clinical Oncology · DOI

Full title: Personalized precision combination therapies based on potential actionability and coalterations and therapeutic opportunities for CDK12-mutated prostate cancer.

Authors: Hong Li, Haitao Wang

Year: 2023

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2023.41.16_suppl.e17068

Paper Combination immunotherapy with interleukin‐2 surface‐modified tumor cell vaccine and programmed death receptor‐1 blockade against renal cell carcinoma

Zhang, Xinji, Shi, Xiaojun, Li, Jin‐Long, Hu, Zhiming, Gao, Jimin, Wu, Shihao, Long, Zhaolin · 2018 · Cancer Science · DOI

Full title: Combination immunotherapy with interleukin‐2 surface‐modified tumor cell vaccine and programmed death receptor‐1 blockade against renal cell carcinoma

Authors: Zhang, Xinji, Shi, Xiaojun, Li, Jin‐Long, Hu, Zhiming, Gao, Jimin, Wu, Shihao, Long, Zhaolin

Year: 2018

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.13842

Paper Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.

Ha, Danbee, Tanaka, Atsushi, Kibayashi, Tatsuya, Tanemura, Atsushi, Sugiyama, Daisuke, Wing, James Badger, Lim, Ee Lyn, Teng, Karen Wei Weng, Adeegbe, Dennis, Newell, Evan W, Katayama, Ichiro, Nishikawa, Hiroyoshi, Sakaguchi, Shimon · 2019 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.

Authors: Ha, Danbee, Tanaka, Atsushi, Kibayashi, Tatsuya, Tanemura, Atsushi, Sugiyama, Daisuke, Wing, James Badger, Lim, Ee Lyn, Teng, Karen Wei Weng, Adeegbe, Dennis, Newell, Evan W, Katayama, Ichiro, Nishikawa, Hiroyoshi, Sakaguchi, Shimon

Year: 2019

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1812186116

Paper Efficacy and Safety of Immune Checkpoint Inhibitors on Advanced Cervical Cancer: A Systematic Review and Meta-analysis.

Wang, Wenhui, Bi, Xiaoning, Feng, Ye, Ming, Xue, Saina, Guo, Kun, Wang, Ling, Bin, Yu, Huan · 2025 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Efficacy and Safety of Immune Checkpoint Inhibitors on Advanced Cervical Cancer: A Systematic Review and Meta-analysis.

Authors: Wang, Wenhui, Bi, Xiaoning, Feng, Ye, Ming, Xue, Saina, Guo, Kun, Wang, Ling, Bin, Yu, Huan

Year: 2025

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0000000000000545

Paper Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer

Shin, Daniel Sanghoon, Park, Kevin, Garon, Edward B., Dubinett, Steven M. · 2022 · Seminars in Oncology · DOI

Full title: Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer

Authors: Shin, Daniel Sanghoon, Park, Kevin, Garon, Edward B., Dubinett, Steven M.

Year: 2022

Venue: Seminars in Oncology

DOI: https://doi.org/10.1053/j.seminoncol.2022.06.005

Paper [Understanding Tumor Immunity by Immune Genome Profiling of the Cancer Tissue].

Kakimi, Kazuhiro · 2022 · Gan to kagaku ryoho. Cancer & chemotherapy

Full title: [Understanding Tumor Immunity by Immune Genome Profiling of the Cancer Tissue].

Authors: Kakimi, Kazuhiro

Year: 2022

Venue: Gan to kagaku ryoho. Cancer & chemotherapy

Paper Unusual Presentation of a Rare Case of Immunotherapy Combination-Induced Encephalitis: A Case Report.

Sfeir, Pamela, Kamar, Francois · 2025 · Case reports in oncology · DOI

Full title: Unusual Presentation of a Rare Case of Immunotherapy Combination-Induced Encephalitis: A Case Report.

Authors: Sfeir, Pamela, Kamar, Francois

Year: 2025

Venue: Case reports in oncology

DOI: https://doi.org/10.1159/000543215

Paper Targeting regulatory T cells in anti-PD-1/PD-L1 cancer immunotherapy.

Zhulai, Galina, Oleinik, Eugenia · 2022 · Scandinavian journal of immunology · DOI

Full title: Targeting regulatory T cells in anti-PD-1/PD-L1 cancer immunotherapy.

Authors: Zhulai, Galina, Oleinik, Eugenia

Year: 2022

Venue: Scandinavian journal of immunology

DOI: https://doi.org/10.1111/sji.13129

Paper The Role of Surgery in Metastatic Renal Cell Carcinoma in 2024.

Leung, David Kw, Ko, Ivan Ch, Siu, Brian Wh, Wong, Chris Hm, Yuen, Steffi Kk, Ng, Chi Fai, Teoh, Jeremy Yc · 2024 · Clinical Medicine Insights. Oncology · DOI

Full title: The Role of Surgery in Metastatic Renal Cell Carcinoma in 2024.

Authors: Leung, David Kw, Ko, Ivan Ch, Siu, Brian Wh, Wong, Chris Hm, Yuen, Steffi Kk, Ng, Chi Fai, Teoh, Jeremy Yc

Year: 2024

Venue: Clinical Medicine Insights. Oncology

DOI: https://doi.org/10.1177/11795549241272447

Paper Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma.

Campbell, Katie M, Amouzgar, Meelad, Pfeiffer, Shannon M, Howes, Timothy R, Medina, Egmidio, Travers, Michael, Steiner, Gabriela, Weber, Jeffrey S, Wolchok, Jedd D, Larkin, James, Hodi, F Stephen, Boffo, Silvia, Salvador, Lisa, Tenney, Daniel, Tang, Tracy, Thompson, Marshall A, Spencer, Christine N, Wells, Daniel K, Ribas, Antoni · 2023 · Cancer cell · DOI

Full title: Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma.

Authors: Campbell, Katie M, Amouzgar, Meelad, Pfeiffer, Shannon M, Howes, Timothy R, Medina, Egmidio, Travers, Michael, Steiner, Gabriela, Weber, Jeffrey S, Wolchok, Jedd D, Larkin, James, Hodi, F Stephen, Boffo, Silvia, Salvador, Lisa, Tenney, Daniel, Tang, Tracy, Thompson, Marshall A, Spencer, Christine N, Wells, Daniel K, Ribas, Antoni

Year: 2023

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2023.03.010

Paper OP01-5 Combination immunotherapy targeting XBP1, CD138 and CS1 with cancer vaccine, checkpoint inhibitors, immune modulator, and epigenetic regulator to treat patients with myeloma or solid tumours: Clinical applications

Jooeun Bae, Kristen Cowens, A. Kimmelman, Sean Rowell, Suzan B. Lazo, D. Keskin, Nikhil C. Munshi, Kenneth Anderson · 2023 · ESMO Open · DOI

Full title: OP01-5 Combination immunotherapy targeting XBP1, CD138 and CS1 with cancer vaccine, checkpoint inhibitors, immune modulator, and epigenetic regulator to treat patients with myeloma or solid tumours: Clinical applications

Authors: Jooeun Bae, Kristen Cowens, A. Kimmelman, Sean Rowell, Suzan B. Lazo, D. Keskin, Nikhil C. Munshi, Kenneth Anderson

Year: 2023

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2023.102126

Paper Lung Cancer: Advances in Diagnosis and Management

Percy Lee, J. Goldman, J. Donington · 2020 · Seminars in Respiratory and Critical Care Medicine · DOI

Full title: Lung Cancer: Advances in Diagnosis and Management

Authors: Percy Lee, J. Goldman, J. Donington

Year: 2020

Venue: Seminars in Respiratory and Critical Care Medicine

DOI: https://doi.org/10.1055/s-0040-1709995

Paper The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity.

Martin, Kea, Müller, Philipp, Schreiner, Jens, Prince, Spasenija Savic, Lardinois, Didier, Heinzelmann-Schwarz, Viola A, Thommen, Daniela S, Zippelius, Alfred · 2014 · Cancer immunology, immunotherapy : CII · DOI

Full title: The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity.

Authors: Martin, Kea, Müller, Philipp, Schreiner, Jens, Prince, Spasenija Savic, Lardinois, Didier, Heinzelmann-Schwarz, Viola A, Thommen, Daniela S, Zippelius, Alfred

Year: 2014

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-014-1565-4

Paper Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy

Iyer, Sonia, Zhang, Shuang, Yucel, Simge, Horn, Heiko, Smith, Sean G., Reinhardt, Ferenc, Hoefsmit, Esmée P., Assatova, Bimarzhan, Casado, Julia, Meinsohn, Marie-Charlotte, Barrasa, M. Inmaculada, Bell, George W., Pérez‐Villatoro, Fernando, Huhtinen, Kaisa, Hynninen, Johanna, Oikkonen, Jaana, Galhenage, Pamoda M., Pathania, Shailja, Hammond, Paula T., Neel, Benjamin G., Färkkilä, Anniina, Pépin, David, Weinberg, Robert A. · 2020 · Cancer Discovery · DOI

Full title: Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy

Authors: Iyer, Sonia, Zhang, Shuang, Yucel, Simge, Horn, Heiko, Smith, Sean G., Reinhardt, Ferenc, Hoefsmit, Esmée P., Assatova, Bimarzhan, Casado, Julia, Meinsohn, Marie-Charlotte, Barrasa, M. Inmaculada, Bell, George W., Pérez‐Villatoro, Fernando, Huhtinen, Kaisa, Hynninen, Johanna, Oikkonen, Jaana, Galhenage, Pamoda M., Pathania, Shailja, Hammond, Paula T., Neel, Benjamin G., Färkkilä, Anniina, Pépin, David, Weinberg, Robert A.

Year: 2020

Venue: Cancer Discovery

DOI: https://doi.org/10.1158/2159-8290.cd-20-0818

Paper Immune checkpoint inhibitors in advanced renal cell carcinoma: experience to date and future directions.

Atkins, M B, Clark, J I, Quinn, D I · 2017 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Immune checkpoint inhibitors in advanced renal cell carcinoma: experience to date and future directions.

Authors: Atkins, M B, Clark, J I, Quinn, D I

Year: 2017

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdx151

Paper Treatment of transplanted CT26 tumour with dendritic cell vaccine in combination with blockade of vascular endothelial growth factor receptor 2 and CTLA-4.

Pedersen, A E, Buus, S, Claesson, M H · 2006 · Cancer letters · DOI

Full title: Treatment of transplanted CT26 tumour with dendritic cell vaccine in combination with blockade of vascular endothelial growth factor receptor 2 and CTLA-4.

Authors: Pedersen, A E, Buus, S, Claesson, M H

Year: 2006

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2005.04.012

Paper Successful Treatment of Immune Checkpoint Inhibitor–Induced Diabetes With Infliximab

Trinh, Beckey, Donath, Marc Y., Läubli, Heinz · 2019 · Diabetes Care · DOI

Full title: Successful Treatment of Immune Checkpoint Inhibitor–Induced Diabetes With Infliximab

Authors: Trinh, Beckey, Donath, Marc Y., Läubli, Heinz

Year: 2019

Venue: Diabetes Care

DOI: https://doi.org/10.2337/dc19-0908

Paper The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.

Farren, Matthew R, Hennessey, Rebecca C, Shakya, Reena, Elnaggar, Omar, Young, Gregory, Kendra, Kari, Landesman, Yosef, Elloul, Sivan, Crochiere, Marsha, Klebanov, Boris, Kashyap, Trinayan, Burd, Christin E, Lesinski, Gregory B · 2017 · Molecular cancer therapeutics · DOI

Full title: The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.

Authors: Farren, Matthew R, Hennessey, Rebecca C, Shakya, Reena, Elnaggar, Omar, Young, Gregory, Kendra, Kari, Landesman, Yosef, Elloul, Sivan, Crochiere, Marsha, Klebanov, Boris, Kashyap, Trinayan, Burd, Christin E, Lesinski, Gregory B

Year: 2017

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-16-0498

Paper Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metastatic colorectal cancer treated with immune checkpoint inhibitors.

Manca, Paolo, Corti, Francesca, Intini, Rossana, Mazzoli, Giacomo, Miceli, Rosalba, Germani, Marco Maria, Bergamo, Francesca, Ambrosini, Margherita, Cristarella, Eleonora, Cerantola, Riccardo, Boccaccio, Chiara, Ricagno, Gianmarco, Ghelardi, Filippo, Randon, Giovanni, Leoncini, Giuseppe, Milione, Massimo, Fassan, Matteo, Cremolini, Chiara, Lonardi, Sara, Pietrantonio, Filippo · 2023 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metastatic colorectal cancer treated with immune checkpoint inhibitors.

Authors: Manca, Paolo, Corti, Francesca, Intini, Rossana, Mazzoli, Giacomo, Miceli, Rosalba, Germani, Marco Maria, Bergamo, Francesca, Ambrosini, Margherita, Cristarella, Eleonora, Cerantola, Riccardo, Boccaccio, Chiara, Ricagno, Gianmarco, Ghelardi, Filippo, Randon, Giovanni, Leoncini, Giuseppe, Milione, Massimo, Fassan, Matteo, Cremolini, Chiara, Lonardi, Sara, Pietrantonio, Filippo

Year: 2023

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2023.03.029

Paper Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C., Guerriero, Jennifer L., Qi, Jun, Long, Henry W., Polyák, Kornélia · 2023 · Molecular Cancer Therapeutics · DOI

Full title: Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Authors: Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C., Guerriero, Jennifer L., Qi, Jun, Long, Henry W., Polyák, Kornélia

Year: 2023

Venue: Molecular Cancer Therapeutics

DOI: https://doi.org/10.1158/1535-7163.mct-23-0303

Paper Indoleamine 2,3-dioxygenase provides adaptive resistance to immune checkpoint inhibitors in hepatocellular carcinoma.

Brown, Zachary J, Yu, Su Jong, Heinrich, Bernd, Ma, Chi, Fu, Qiong, Sandhu, Milan, Agdashian, David, Zhang, Qianfei, Korangy, Firouzeh, Greten, Tim F · 2018 · Cancer immunology, immunotherapy : CII · DOI

Full title: Indoleamine 2,3-dioxygenase provides adaptive resistance to immune checkpoint inhibitors in hepatocellular carcinoma.

Authors: Brown, Zachary J, Yu, Su Jong, Heinrich, Bernd, Ma, Chi, Fu, Qiong, Sandhu, Milan, Agdashian, David, Zhang, Qianfei, Korangy, Firouzeh, Greten, Tim F

Year: 2018

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-018-2190-4

Paper Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34.

Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem · 2020 · Autophagy · DOI

Full title: Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34.

Authors: Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1815439

Paper Pharmacovigilance study on the reporting frequency of atrial fibrillation with immune checkpoint inhibitors: insights from FDA Adverse Event Reporting System.

Balzano, Nunzia, Mascolo, Annamaria, Ruggiero, Donatella, Rafaniello, Concetta, Paolisso, Giuseppe, Rossi, Francesco, Capuano, Annalisa · 2025 · Therapeutic advances in drug safety · DOI

Full title: Pharmacovigilance study on the reporting frequency of atrial fibrillation with immune checkpoint inhibitors: insights from FDA Adverse Event Reporting System.

Authors: Balzano, Nunzia, Mascolo, Annamaria, Ruggiero, Donatella, Rafaniello, Concetta, Paolisso, Giuseppe, Rossi, Francesco, Capuano, Annalisa

Year: 2025

Venue: Therapeutic advances in drug safety

DOI: https://doi.org/10.1177/20420986241312497

Paper Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling.

Yofe, Ido, Landsberger, Tomer, Yalin, Adam, Solomon, Isabelle, Costoya, Cristobal, Demane, Dafne Franz, Shah, Mansi, David, Eyal, Borenstein, Chamutal, Barboy, Oren, Matos, Ignacio, Peggs, Karl S, Quezada, Sergio A, Amit, Ido · 2022 · Nature cancer · DOI

Full title: Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling.

Authors: Yofe, Ido, Landsberger, Tomer, Yalin, Adam, Solomon, Isabelle, Costoya, Cristobal, Demane, Dafne Franz, Shah, Mansi, David, Eyal, Borenstein, Chamutal, Barboy, Oren, Matos, Ignacio, Peggs, Karl S, Quezada, Sergio A, Amit, Ido

Year: 2022

Venue: Nature cancer

DOI: https://doi.org/10.1038/s43018-022-00447-1

Paper Immune checkpoint inhibitor resumption after discontinuation due to immune-related adverse events: a nomogram-based analysis of risk factors and outcomes.

Acar, Caner, Yüksel, Haydar Çağatay, Şahin, Gökhan, Açar, Fatma Pinar, Karaca, Burçak · 2025 · Expert review of anticancer therapy · DOI

Full title: Immune checkpoint inhibitor resumption after discontinuation due to immune-related adverse events: a nomogram-based analysis of risk factors and outcomes.

Authors: Acar, Caner, Yüksel, Haydar Çağatay, Şahin, Gökhan, Açar, Fatma Pinar, Karaca, Burçak

Year: 2025

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2025.2517274

Paper Immunotherapy for the treatment of breast cancer: checkpoint blockade, cancer vaccines, and future directions in combination immunotherapy.

McArthur, Heather L., Page, David B. · 2016 · PubMed

Full title: Immunotherapy for the treatment of breast cancer: checkpoint blockade, cancer vaccines, and future directions in combination immunotherapy.

Authors: McArthur, Heather L., Page, David B.

Year: 2016

Venue: PubMed

Paper Abstract 2389: In vivo multiphoton autofluorescence imaging is sensitive to CD8 T cell and tumor cell metabolic changes during immunotherapy in a murine melanoma model

A. Heaton, A. Hoefges, Peter R. Rehani, Nathaniel J Burkard, Arika S. Feils, D. Spiegelman, N. Tsarovsky, Alina A. Hampton, Amy K. Erbe Gurel, A. Rakhmilevich, P. Sondel, M. Skala · 2023 · Cancer Research · DOI

Full title: Abstract 2389: In vivo multiphoton autofluorescence imaging is sensitive to CD8 T cell and tumor cell metabolic changes during immunotherapy in a murine melanoma model

Authors: A. Heaton, A. Hoefges, Peter R. Rehani, Nathaniel J Burkard, Arika S. Feils, D. Spiegelman, N. Tsarovsky, Alina A. Hampton, Amy K. Erbe Gurel, A. Rakhmilevich, P. Sondel, M. Skala

Year: 2023

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2023-2389

Paper Combining microenvironment normalization strategies to improve cancer immunotherapy

Mpekris, Fotios, Voutouri, Chrysovalantis, Baish, James W., Duda, Dan G., Munn, Lance L., Stylianopoulos, Triantafyllos, Jain, Rakesh K. · 2020 · Proceedings of the National Academy of Sciences · DOI

Full title: Combining microenvironment normalization strategies to improve cancer immunotherapy

Authors: Mpekris, Fotios, Voutouri, Chrysovalantis, Baish, James W., Duda, Dan G., Munn, Lance L., Stylianopoulos, Triantafyllos, Jain, Rakesh K.

Year: 2020

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1919764117

Paper Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies.

D'Souza, Neil M, Fang, Penny, Logan, Jennifer, Yang, Jinzhong, Jiang, Wen, Li, Jing · 2016 · Frontiers in oncology · DOI

Full title: Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies.

Authors: D'Souza, Neil M, Fang, Penny, Logan, Jennifer, Yang, Jinzhong, Jiang, Wen, Li, Jing

Year: 2016

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2016.00212

Paper Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy.

Vila-Leahey, Ava, MacKay, Alecia, Portales-Cervantes, Liliana, Weir, Genevieve M, Merkx-Jacques, Alexandra, Stanford, Marianne M · 2020 · Oncoimmunology · DOI

Full title: Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy.

Authors: Vila-Leahey, Ava, MacKay, Alecia, Portales-Cervantes, Liliana, Weir, Genevieve M, Merkx-Jacques, Alexandra, Stanford, Marianne M

Year: 2020

Venue: Oncoimmunology

DOI: https://doi.org/10.1080/2162402X.2020.1782574

Paper Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells.

Yoneda, Hiroto, Mitsuhashi, Atsushi, Yoshida, Aito, Ogino, Hirokazu, Itakura, Satoshi, Nguyen, Na Thi, Nokihara, Hiroshi, Sato, Seidai, Shinohara, Tsutomu, Hanibuchi, Masaki, Abe, Shinji, Kaneko, Mika K, Kato, Yukinari, Nishioka, Yasuhiko · 2024 · Cancer science · DOI

Full title: Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells.

Authors: Yoneda, Hiroto, Mitsuhashi, Atsushi, Yoshida, Aito, Ogino, Hirokazu, Itakura, Satoshi, Nguyen, Na Thi, Nokihara, Hiroshi, Sato, Seidai, Shinohara, Tsutomu, Hanibuchi, Masaki, Abe, Shinji, Kaneko, Mika K, Kato, Yukinari, Nishioka, Yasuhiko

Year: 2024

Venue: Cancer science

DOI: https://doi.org/10.1111/cas.16046

Paper Meta-analysis of immune-related adverse events of immune checkpoint inhibitor therapy in cancer patients.

Song, Peng, Zhang, Dingding, Cui, Xiaoxia, Zhang, Li · 2020 · Thoracic cancer · DOI

Full title: Meta-analysis of immune-related adverse events of immune checkpoint inhibitor therapy in cancer patients.

Authors: Song, Peng, Zhang, Dingding, Cui, Xiaoxia, Zhang, Li

Year: 2020

Venue: Thoracic cancer

DOI: https://doi.org/10.1111/1759-7714.13541

Paper Long-lasting Complete Remission Following Immunotherapy With Anti-PD1 Plus Anti-CTLA4 in a Polymetastatic Patient With NRAS (Q16R) Mutated Anaplastic Thyroid Carcinoma.

Anzellini, Dimitri, Loddo, Marco, Del Bianco, Sergio · 2025 · Anticancer research · DOI

Full title: Long-lasting Complete Remission Following Immunotherapy With Anti-PD1 Plus Anti-CTLA4 in a Polymetastatic Patient With NRAS (Q16R) Mutated Anaplastic Thyroid Carcinoma.

Authors: Anzellini, Dimitri, Loddo, Marco, Del Bianco, Sergio

Year: 2025

Venue: Anticancer research

DOI: https://doi.org/10.21873/anticanres.17740

Paper Bispecific antibodies (bsAbs) directed against PD-1/PD-L1 and CTLA-4; a mini review.

Mardi, Amirhossein, Aghebati-Maleki, Leili · 2025 · Human antibodies · DOI

Full title: Bispecific antibodies (bsAbs) directed against PD-1/PD-L1 and CTLA-4; a mini review.

Authors: Mardi, Amirhossein, Aghebati-Maleki, Leili

Year: 2025

Venue: Human antibodies

DOI: https://doi.org/10.1177/10932607251325751

Paper Plasma cytokines interleukin-18 and C-X-C motif chemokine ligand 10 are indicative of the anti-programmed cell death protein-1 treatment response in lung cancer patients.

Wang, Yida, Chen, Hanxiao, Zhang, Tianzhuo, Yang, Xue, Zhong, Jia, Wang, Yuyan, Chi, Yujia, Wu, Meina, An, Tongtong, Li, Jianjie, Zhao, Xinghui, Dong, Zhi, Wang, Ziping, Zhao, Jun, Zhuo, Minglei, Huang, Jing · 2021 · Annals of translational medicine · DOI

Full title: Plasma cytokines interleukin-18 and C-X-C motif chemokine ligand 10 are indicative of the anti-programmed cell death protein-1 treatment response in lung cancer patients.

Authors: Wang, Yida, Chen, Hanxiao, Zhang, Tianzhuo, Yang, Xue, Zhong, Jia, Wang, Yuyan, Chi, Yujia, Wu, Meina, An, Tongtong, Li, Jianjie, Zhao, Xinghui, Dong, Zhi, Wang, Ziping, Zhao, Jun, Zhuo, Minglei, Huang, Jing

Year: 2021

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm-20-1513

Paper Reviewer #1 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: Reviewer #1 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2.sa2

Paper A New Combination Immunotherapy in Advanced Melanoma.

Frampton, Adam E, Sivakumar, Shivan · 2022 · The New England journal of medicine · DOI

Full title: A New Combination Immunotherapy in Advanced Melanoma.

Authors: Frampton, Adam E, Sivakumar, Shivan

Year: 2022

Venue: The New England journal of medicine

DOI: https://doi.org/10.1056/NEJMe2116892

Paper TAMI-23. ANTIBODY COCKTAIL IMMUNOTHERAPY FOR GLIOBLASTOMA BY DUAL TARGETING OF IL-6 AND CD40

Fan Yang, S. Brem, Yi Fan · 2021 · Neuro-Oncology · DOI

Full title: TAMI-23. ANTIBODY COCKTAIL IMMUNOTHERAPY FOR GLIOBLASTOMA BY DUAL TARGETING OF IL-6 AND CD40

Authors: Fan Yang, S. Brem, Yi Fan

Year: 2021

Venue: Neuro-Oncology

DOI: https://doi.org/10.1093/neuonc/noab196.807

Paper Combination immunotherapy in a patient with hemodialysis therapy and metachronous bilateral clear cell renal cell carcinoma: Case report and literature review.

Isaza, Alejandro Pineda, Franco, Alvaro Osorio, Quintero González, Lisceth Paola, Fajardo, Marcela Vallejo · 2022 · Urology case reports · DOI

Full title: Combination immunotherapy in a patient with hemodialysis therapy and metachronous bilateral clear cell renal cell carcinoma: Case report and literature review.

Authors: Isaza, Alejandro Pineda, Franco, Alvaro Osorio, Quintero González, Lisceth Paola, Fajardo, Marcela Vallejo

Year: 2022

Venue: Urology case reports

DOI: https://doi.org/10.1016/j.eucr.2022.102242

Paper Research Progress of PD-1/PD-L1 Inhibitors in the Treatment of Advanced Gastric Carcinoma

雨婷李 · 2023 · Advances in Clinical Medicine · DOI

Full title: Research Progress of PD-1/PD-L1 Inhibitors in the Treatment of Advanced Gastric Carcinoma

Authors: 雨婷李

Year: 2023

Venue: Advances in Clinical Medicine

DOI: https://doi.org/10.12677/acm.2023.135993

Paper Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Series

J. Palmer, A. Suriawinata, Shaofeng Yan, D. A. Kerr, M. Afzal, Keisuke Shirai · 2023 · The American journal of case reports · DOI

Full title: Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Series

Authors: J. Palmer, A. Suriawinata, Shaofeng Yan, D. A. Kerr, M. Afzal, Keisuke Shirai

Year: 2023

Venue: The American journal of case reports

DOI: https://doi.org/10.12659/ajcr.938537

Paper Propelling Immunotherapy Combinations Into the Clinic.

Tchekmedyian, Nishan, Gray, Jhanelle E, Creelan, Benjamin C, Chiappori, Alberto A, Beg, Amer A, Soliman, Hatem, Perez, Bradford A, Antonia, Scott J · 2015 · Oncology (Williston Park, N.Y.)

Full title: Propelling Immunotherapy Combinations Into the Clinic.

Authors: Tchekmedyian, Nishan, Gray, Jhanelle E, Creelan, Benjamin C, Chiappori, Alberto A, Beg, Amer A, Soliman, Hatem, Perez, Bradford A, Antonia, Scott J

Year: 2015

Venue: Oncology (Williston Park, N.Y.)

Paper Ipilimumab after progression on anti-PD-1 treatment in advanced melanoma.

Aya, Francisco, Gaba, Lydia, Victoria, Iván, Fernández-Martínez, Aranzazu, Tosca, Mónica, Prat, Aleix, Arance, Ana · 2016 · Future oncology (London, England) · DOI

Full title: Ipilimumab after progression on anti-PD-1 treatment in advanced melanoma.

Authors: Aya, Francisco, Gaba, Lydia, Victoria, Iván, Fernández-Martínez, Aranzazu, Tosca, Mónica, Prat, Aleix, Arance, Ana

Year: 2016

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2016-0037

Paper Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites.

Kluger, Harriet M, Zito, Christopher R, Barr, Meaghan L, Baine, Marina K, Chiang, Veronica L S, Sznol, Mario, Rimm, David L, Chen, Lieping, Jilaveanu, Lucia B · 2015 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites.

Authors: Kluger, Harriet M, Zito, Christopher R, Barr, Meaghan L, Baine, Marina K, Chiang, Veronica L S, Sznol, Mario, Rimm, David L, Chen, Lieping, Jilaveanu, Lucia B

Year: 2015

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-14-3073

Paper Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

Blank, Christian U, Rozeman, Elisa A, Fanchi, Lorenzo F, Sikorska, Karolina, van de Wiel, Bart, Kvistborg, Pia, Krijgsman, Oscar, van den Braber, Marlous, Philips, Daisy, Broeks, Annegien, van Thienen, Johannes V, Mallo, Henk A, Adriaansz, Sandra, Ter Meulen, Sylvia, Pronk, Loes M, Grijpink-Ongering, Lindsay G, Bruining, Annemarie, Gittelman, Rachel M, Warren, Sarah, van Tinteren, Harm, Peeper, Daniel S, Haanen, John B A G, van Akkooi, Alexander C J, Schumacher, Ton N · 2018 · Nature medicine · DOI

Full title: Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

Authors: Blank, Christian U, Rozeman, Elisa A, Fanchi, Lorenzo F, Sikorska, Karolina, van de Wiel, Bart, Kvistborg, Pia, Krijgsman, Oscar, van den Braber, Marlous, Philips, Daisy, Broeks, Annegien, van Thienen, Johannes V, Mallo, Henk A, Adriaansz, Sandra, Ter Meulen, Sylvia, Pronk, Loes M, Grijpink-Ongering, Lindsay G, Bruining, Annemarie, Gittelman, Rachel M, Warren, Sarah, van Tinteren, Harm, Peeper, Daniel S, Haanen, John B A G, van Akkooi, Alexander C J, Schumacher, Ton N

Year: 2018

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-018-0198-0

Paper Microfluidic Protocols for the Assessment of Anticancer Therapies in 3D Tumor-Stromal Cocultures.

Paterson, Karla, Zagnoni, Michele · 2023 · Methods in molecular biology (Clifton, N.J.) · DOI

Full title: Microfluidic Protocols for the Assessment of Anticancer Therapies in 3D Tumor-Stromal Cocultures.

Authors: Paterson, Karla, Zagnoni, Michele

Year: 2023

Venue: Methods in molecular biology (Clifton, N.J.)

DOI: https://doi.org/10.1007/978-1-0716-3271-0_8

Paper Prognostic effect of coexisting TP53 and ZFHX3 mutations in non-small cell lung cancer patients treated with immune checkpoint inhibitors.

Zhang, Lijuan, Zhang, Tongyan, Shang, Bin, Li, Yaqiong, Cao, Zhixin, Wang, Hui · 2021 · Scandinavian journal of immunology · DOI

Full title: Prognostic effect of coexisting TP53 and ZFHX3 mutations in non-small cell lung cancer patients treated with immune checkpoint inhibitors.

Authors: Zhang, Lijuan, Zhang, Tongyan, Shang, Bin, Li, Yaqiong, Cao, Zhixin, Wang, Hui

Year: 2021

Venue: Scandinavian journal of immunology

DOI: https://doi.org/10.1111/sji.13087

Paper Complete response to pembrolizumab after initial progress in a patient with metastatic uveal melanoma

Camila Toledo Stauner, K. Drexler, M. Berneburg, S. Haferkamp · 2018 · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · DOI

Full title: Complete response to pembrolizumab after initial progress in a patient with metastatic uveal melanoma

Authors: Camila Toledo Stauner, K. Drexler, M. Berneburg, S. Haferkamp

Year: 2018

Venue: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

DOI: https://doi.org/10.1111/ddg.13660

Paper Abstract 519: Hyperprogression in follicular thyroid cancer treated with combination immunotherapy

Lee, Yeun Ho, Kim, Leeseul, Nam, Myungwoo, Cheng, William, Hur, Won Kyung, Hwang, Jin Young, Choi, Yoon‐Hee, Bae, William Han, Kim, Eugene, Cho, Heayoon Shauna, Yu, Emma, Jung, Chan Mi, Low, Christmann, Vagia, Elena, Chae, Young Kwang · 2021 · Cancer Research · DOI

Full title: Abstract 519: Hyperprogression in follicular thyroid cancer treated with combination immunotherapy

Authors: Lee, Yeun Ho, Kim, Leeseul, Nam, Myungwoo, Cheng, William, Hur, Won Kyung, Hwang, Jin Young, Choi, Yoon‐Hee, Bae, William Han, Kim, Eugene, Cho, Heayoon Shauna, Yu, Emma, Jung, Chan Mi, Low, Christmann, Vagia, Elena, Chae, Young Kwang

Year: 2021

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2021-519

Paper FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2.

Meng Xie, Zhuoying Lin, Xiaoyu Ji, Xiangyuan Luo, Zerui Zhang, Mengyu Sun, Xiaoping Chen, Bi-xiang Zhang, Hui-fang Liang, Danfei Liu, Yangyang Feng, Yijun Wang, Yiwei Li, Bifeng Liu, Wenjie Huang, L. Xia · 2023 · Journal of Hepatology · DOI

Full title: FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2.

Authors: Meng Xie, Zhuoying Lin, Xiaoyu Ji, Xiangyuan Luo, Zerui Zhang, Mengyu Sun, Xiaoping Chen, Bi-xiang Zhang, Hui-fang Liang, Danfei Liu, Yangyang Feng, Yijun Wang, Yiwei Li, Bifeng Liu, Wenjie Huang, L. Xia

Year: 2023

Venue: Journal of Hepatology

DOI: https://doi.org/10.1016/j.jhep.2023.02.036

Paper Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulation of MCF-7 breast cancer cells.

Hosseinkhani, Negar, Alipour, Shiva, Ghaffari Jolfayi, Amir, Aghebati-Maleki, Leili, Baghbani, Elham, Alizadeh, Nazila, Khaze, Vahid, Baradaran, Behzad · 2025 · Cytotechnology · DOI

Full title: Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulation of MCF-7 breast cancer cells.

Authors: Hosseinkhani, Negar, Alipour, Shiva, Ghaffari Jolfayi, Amir, Aghebati-Maleki, Leili, Baghbani, Elham, Alizadeh, Nazila, Khaze, Vahid, Baradaran, Behzad

Year: 2025

Venue: Cytotechnology

DOI: https://doi.org/10.1007/s10616-024-00677-4

Paper Incidence of Thyroid Function Test Abnormalities in Patients Receiving Immune-Checkpoint Inhibitors for Cancer Treatment.

Patel, Nisha Subhash, Oury, Anais, Daniels, Gregory A, Bazhenova, Lyudmila, Patel, Sandip Pravin · 2018 · The oncologist · DOI

Full title: Incidence of Thyroid Function Test Abnormalities in Patients Receiving Immune-Checkpoint Inhibitors for Cancer Treatment.

Authors: Patel, Nisha Subhash, Oury, Anais, Daniels, Gregory A, Bazhenova, Lyudmila, Patel, Sandip Pravin

Year: 2018

Venue: The oncologist

DOI: https://doi.org/10.1634/theoncologist.2017-0375

Paper HHLA2 and PD-L1 co-expression predicts poor prognosis in patients with clear cell renal cell carcinoma

Zhou, Qiang-Hua, Li, Kai-Wen, Chen, Xu, He, Hai-Xia, Peng, Sheng-Meng, Peng, Shi-Rong, Wang, Qiong, Li, Ze-An, Tao, Yi-Ran, Cai, Wenli, Liu, Ran-Yi, Huang, Hai · 2020 · Journal for ImmunoTherapy of Cancer · DOI

Full title: HHLA2 and PD-L1 co-expression predicts poor prognosis in patients with clear cell renal cell carcinoma

Authors: Zhou, Qiang-Hua, Li, Kai-Wen, Chen, Xu, He, Hai-Xia, Peng, Sheng-Meng, Peng, Shi-Rong, Wang, Qiong, Li, Ze-An, Tao, Yi-Ran, Cai, Wenli, Liu, Ran-Yi, Huang, Hai

Year: 2020

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2019-000157

Paper Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer.

Zielinski, C, Knapp, S, Mascaux, C, Hirsch, F · 2013 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer.

Authors: Zielinski, C, Knapp, S, Mascaux, C, Hirsch, F

Year: 2013

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mds647

Paper Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.

Gide, Tuba N, Quek, Camelia, Menzies, Alexander M, Tasker, Annie T, Shang, Ping, Holst, Jeff, Madore, Jason, Lim, Su Yin, Velickovic, Rebecca, Wongchenko, Matthew, Yan, Yibing, Lo, Serigne, Carlino, Matteo S, Guminski, Alexander, Saw, Robyn P M, Pang, Angel, McGuire, Helen M, Palendira, Umaimainthan, Thompson, John F, Rizos, Helen, Silva, Ines Pires da, Batten, Marcel, Scolyer, Richard A, Long, Georgina V, Wilmott, James S · 2019 · Cancer cell · DOI

Full title: Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.

Authors: Gide, Tuba N, Quek, Camelia, Menzies, Alexander M, Tasker, Annie T, Shang, Ping, Holst, Jeff, Madore, Jason, Lim, Su Yin, Velickovic, Rebecca, Wongchenko, Matthew, Yan, Yibing, Lo, Serigne, Carlino, Matteo S, Guminski, Alexander, Saw, Robyn P M, Pang, Angel, McGuire, Helen M, Palendira, Umaimainthan, Thompson, John F, Rizos, Helen, Silva, Ines Pires da, Batten, Marcel, Scolyer, Richard A, Long, Georgina V, Wilmott, James S

Year: 2019

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2019.01.003

Paper Efficacy and safety of PD‐1/PD‐L1 inhibitor plus chemotherapy versus chemotherapy alone as first‐line treatment for extensive‐stage small cell lung cancer: A systematic review and meta‐analysis

Shuang Zhang, Shuang Li, Ying Cheng · 2020 · Thoracic Cancer · DOI

Full title: Efficacy and safety of PD‐1/PD‐L1 inhibitor plus chemotherapy versus chemotherapy alone as first‐line treatment for extensive‐stage small cell lung cancer: A systematic review and meta‐analysis

Authors: Shuang Zhang, Shuang Li, Ying Cheng

Year: 2020

Venue: Thoracic Cancer

DOI: https://doi.org/10.1111/1759-7714.13698

Paper Emerging Therapeutic Strategies of Different Immunotherapy Approaches Combined with PD-1/PD-L1 Blockade in Cervical Cancer.

Ge, Yanjun, Zhang, Yuchen, Zhao, Kong-Nan, Zhu, Haiyan · 2022 · Drug design, development and therapy · DOI

Full title: Emerging Therapeutic Strategies of Different Immunotherapy Approaches Combined with PD-1/PD-L1 Blockade in Cervical Cancer.

Authors: Ge, Yanjun, Zhang, Yuchen, Zhao, Kong-Nan, Zhu, Haiyan

Year: 2022

Venue: Drug design, development and therapy

DOI: https://doi.org/10.2147/DDDT.S374672

Paper Chinese Multidisciplinary Expert Consensus on Immune Checkpoint Inhibitor-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition).

Liu, Xiufeng, Lu, Yinying, Zhou, Weiping, Peng, Tao, Zhou, Jie, Bi, Huaqiang, Xia, Feng, Chen, Xiaoping · 2024 · Liver cancer · DOI

Full title: Chinese Multidisciplinary Expert Consensus on Immune Checkpoint Inhibitor-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition).

Authors: Liu, Xiufeng, Lu, Yinying, Zhou, Weiping, Peng, Tao, Zhou, Jie, Bi, Huaqiang, Xia, Feng, Chen, Xiaoping

Year: 2024

Venue: Liver cancer

DOI: https://doi.org/10.1159/000535496

Paper An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice.

Loser, Karin, Scherer, Andrea, Krummen, Mathias B W, Varga, Georg, Higuchi, Tetsuya, Schwarz, Thomas, Sharpe, Arlene H, Grabbe, Stephan, Bluestone, Jeffrey A, Beissert, Stefan · 2005 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice.

Authors: Loser, Karin, Scherer, Andrea, Krummen, Mathias B W, Varga, Georg, Higuchi, Tetsuya, Schwarz, Thomas, Sharpe, Arlene H, Grabbe, Stephan, Bluestone, Jeffrey A, Beissert, Stefan

Year: 2005

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.174.9.5298

Paper Patterns and genomic correlates of PD-L1 expression in patients with biliary tract cancers

Mody, Kabir, Starr, Jason S., Saul, Michelle, Poorman, Kelsey, Weinberg, Benjamin A., Salem, Mohamed E., Vanderwalde, Ari M., Shields, Anthony F. · 2019 · Journal of Gastrointestinal Oncology · DOI

Full title: Patterns and genomic correlates of PD-L1 expression in patients with biliary tract cancers

Authors: Mody, Kabir, Starr, Jason S., Saul, Michelle, Poorman, Kelsey, Weinberg, Benjamin A., Salem, Mohamed E., Vanderwalde, Ari M., Shields, Anthony F.

Year: 2019

Venue: Journal of Gastrointestinal Oncology

DOI: https://doi.org/10.21037/jgo.2019.08.08

Paper Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models.

Dong, Lauren, Choi, Hyejin, Budhu, Sadna, Schulze, Isabell, Verma, Svena, Mangarin, Levi M, Estrada Nevarro, Valeria, Mehanna, Nezar, Khan, Jonathan F, Venkatesh, Divya, Thach, Daniel, Rosen, Neal, Wolchok, Jedd D, Merghoub, Taha · 2024 · Cancer immunology research · DOI

Full title: Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models.

Authors: Dong, Lauren, Choi, Hyejin, Budhu, Sadna, Schulze, Isabell, Verma, Svena, Mangarin, Levi M, Estrada Nevarro, Valeria, Mehanna, Nezar, Khan, Jonathan F, Venkatesh, Divya, Thach, Daniel, Rosen, Neal, Wolchok, Jedd D, Merghoub, Taha

Year: 2024

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-23-0729

Paper Datasets for gene expression profiles of head and neck squamous cell carcinoma and lung cancer treated or not by PD1/PD-L1 inhibitors.

Full title: Datasets for gene expression profiles of head and neck squamous cell carcinoma and lung cancer treated or not by PD1/PD-L1 inhibitors.

Year: 2022

Venue: Data in brief

DOI: https://doi.org/10.1016/j.dib.2022.108556

Paper Role of dendritic cell metabolic reprogramming in tumor immune evasion.

Plebanek, Michael P, Sturdivant, Michael, DeVito, Nicholas C, Hanks, Brent A · 2020 · International immunology · DOI

Full title: Role of dendritic cell metabolic reprogramming in tumor immune evasion.

Authors: Plebanek, Michael P, Sturdivant, Michael, DeVito, Nicholas C, Hanks, Brent A

Year: 2020

Venue: International immunology

DOI: https://doi.org/10.1093/intimm/dxaa036

Paper Abstract PO3-06-09: A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer

Page, David B., Hall, Alexander, Collins, Krystle, Moxon, Nicole, Mellinger, Staci, Kelly, Tracy, Kelley, Aysha, Fredrich, Nicole, Seino, Amanda Y., Liberatore, G., Conlin, Alison, Topp, Zheng, Perlewitz, Kelly S., Stanton, Sasha E., Urba, Walter J., Wu, Yaping, Martel, Maritza, Sun, Zhaoyu, Kogushi, Yoshinobu, Redmond, William L., Traina, Tiffany A., Guculp, Ayca · 2024 · Cancer Research · DOI

Full title: Abstract PO3-06-09: A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer

Authors: Page, David B., Hall, Alexander, Collins, Krystle, Moxon, Nicole, Mellinger, Staci, Kelly, Tracy, Kelley, Aysha, Fredrich, Nicole, Seino, Amanda Y., Liberatore, G., Conlin, Alison, Topp, Zheng, Perlewitz, Kelly S., Stanton, Sasha E., Urba, Walter J., Wu, Yaping, Martel, Maritza, Sun, Zhaoyu, Kogushi, Yoshinobu, Redmond, William L., Traina, Tiffany A., Guculp, Ayca

Year: 2024

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.sabcs23-po3-06-09

Paper VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy.

Lines, J Louise, Sempere, Lorenzo F, Broughton, Thomas, Wang, Li, Noelle, Randolph · 2014 · Cancer immunology research · DOI

Full title: VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy.

Authors: Lines, J Louise, Sempere, Lorenzo F, Broughton, Thomas, Wang, Li, Noelle, Randolph

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0072

Paper [Strategies and perspectives for addressing immune checkpoint inhibitor resistance in the era of combination immunotherapy for advanced hepatocellular carcinoma].

Ogasawara, Sadahisa, Kanogawa, Naoya, Kato, Naoya · 2024 · Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology · DOI

Full title: [Strategies and perspectives for addressing immune checkpoint inhibitor resistance in the era of combination immunotherapy for advanced hepatocellular carcinoma].

Authors: Ogasawara, Sadahisa, Kanogawa, Naoya, Kato, Naoya

Year: 2024

Venue: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology

DOI: https://doi.org/10.11405/nisshoshi.121.737

Paper Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders.

Brown, Lauren J, Weppler, Alison, Bhave, Prachi, Allayous, Clara, Patrinely, J Randall, Ott, Patrick, Sandhu, Shahneen, Haydon, Andrew, Lebbe, Celeste, Johnson, Douglas B, Long, Georgina V, Menzies, Alexander A, Carlino, Matteo S · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders.

Authors: Brown, Lauren J, Weppler, Alison, Bhave, Prachi, Allayous, Clara, Patrinely, J Randall, Ott, Patrick, Sandhu, Shahneen, Haydon, Andrew, Lebbe, Celeste, Johnson, Douglas B, Long, Georgina V, Menzies, Alexander A, Carlino, Matteo S

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-002121

Paper Hematological toxicities in immune checkpoint inhibitors: A pharmacovigilance study from 2014 to 2019.

Ye, Xiaofei, Hu, Fangyuan, Zhai, Yinghong, Qin, Yingyi, Xu, Jinfang, Guo, Xiaojing, Zhuang, Yonglong, He, Jia · 2020 · Hematological oncology · DOI

Full title: Hematological toxicities in immune checkpoint inhibitors: A pharmacovigilance study from 2014 to 2019.

Authors: Ye, Xiaofei, Hu, Fangyuan, Zhai, Yinghong, Qin, Yingyi, Xu, Jinfang, Guo, Xiaojing, Zhuang, Yonglong, He, Jia

Year: 2020

Venue: Hematological oncology

DOI: https://doi.org/10.1002/hon.2743

Paper PD-L1 expression and outcome of advanced melanoma patients treated with anti-PD-1/PD-L1 agents: a meta-analysis.

Abdel-Rahman, Omar · 2016 · Immunotherapy · DOI

Full title: PD-L1 expression and outcome of advanced melanoma patients treated with anti-PD-1/PD-L1 agents: a meta-analysis.

Authors: Abdel-Rahman, Omar

Year: 2016

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2016-0025

Paper Immune checkpoint inhibitors for unresectable malignant pleural mesothelioma.

Metro, Giulio, Signorelli, Diego, Pizzutilo, Elio G, Giannetta, Laura, Cerea, Giulio, Garaffa, Miriam, Friedlaender, Alex, Addeo, Alfredo, Mandarano, Martina, Bellezza, Guido, Roila, Fausto · 2021 · Human vaccines & immunotherapeutics · DOI

Full title: Immune checkpoint inhibitors for unresectable malignant pleural mesothelioma.

Authors: Metro, Giulio, Signorelli, Diego, Pizzutilo, Elio G, Giannetta, Laura, Cerea, Giulio, Garaffa, Miriam, Friedlaender, Alex, Addeo, Alfredo, Mandarano, Martina, Bellezza, Guido, Roila, Fausto

Year: 2021

Venue: Human vaccines & immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2021.1917933

Paper Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy.

Lauret Marie Joseph, Elodie, Kirilovsky, Amos, Lecoester, Benoît, El Sissy, Carine, Boullerot, Laura, Rangan, Laurie, Marguier, Amélie, Tochet, Florent, Dosset, Magalie, Boustani, Jihane, Ravel, Patrice, Boidot, Romain, Spehner, Laurie, Haicheur-Adjouri, Nacilla, Marliot, Florence, Pallandre, Jean-René, Bonnefoy, Francis, Scripcariu, Viorel, Van den Eynde, Marc, Cornillot, Emmanuel, Mirjolet, Céline, Pages, Franck, Adotevi, Olivier · 2021 · Journal for immunotherapy of cancer · DOI

Full title: Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy.

Authors: Lauret Marie Joseph, Elodie, Kirilovsky, Amos, Lecoester, Benoît, El Sissy, Carine, Boullerot, Laura, Rangan, Laurie, Marguier, Amélie, Tochet, Florent, Dosset, Magalie, Boustani, Jihane, Ravel, Patrice, Boidot, Romain, Spehner, Laurie, Haicheur-Adjouri, Nacilla, Marliot, Florence, Pallandre, Jean-René, Bonnefoy, Francis, Scripcariu, Viorel, Van den Eynde, Marc, Cornillot, Emmanuel, Mirjolet, Céline, Pages, Franck, Adotevi, Olivier

Year: 2021

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2020-002256

Paper Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherapy, in advanced mucosal melanoma patients: A retrospective, multicenter study.

Umeda, Yoshiyasu, Yoshikawa, Shusuke, Kiniwa, Yukiko, Maekawa, Takeo, Yamasaki, Osamu, Isei, Taiki, Matsushita, Shigeto, Nomura, Motoo, Nakai, Yasuo, Fukushima, Satoshi, Saito, Shintaro, Takenouchi, Tatsuya, Tanaka, Ryo, Kato, Hiroshi, Otsuka, Atsushi, Matsuya, Taisuke, Baba, Natsuki, Nagase, Kotaro, Inozume, Takashi, Onuma, Takehiro, Kuwatsuka, Yutaka, Fujimoto, Noriki, Kaneko, Takahide, Onishi, Masazumi, Namikawa, Kenjiro, Yamazaki, Naoya, Nakamura, Yasuhiro · 2021 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherapy, in advanced mucosal melanoma patients: A retrospective, multicenter study.

Authors: Umeda, Yoshiyasu, Yoshikawa, Shusuke, Kiniwa, Yukiko, Maekawa, Takeo, Yamasaki, Osamu, Isei, Taiki, Matsushita, Shigeto, Nomura, Motoo, Nakai, Yasuo, Fukushima, Satoshi, Saito, Shintaro, Takenouchi, Tatsuya, Tanaka, Ryo, Kato, Hiroshi, Otsuka, Atsushi, Matsuya, Taisuke, Baba, Natsuki, Nagase, Kotaro, Inozume, Takashi, Onuma, Takehiro, Kuwatsuka, Yutaka, Fujimoto, Noriki, Kaneko, Takahide, Onishi, Masazumi, Namikawa, Kenjiro, Yamazaki, Naoya, Nakamura, Yasuhiro

Year: 2021

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2021.08.034

Paper Nonredundant Immune Checkpoints Direct Therapeutic Resistance to Chemoimmunotherapy in Pancreatic Ductal Adenocarcinoma.

Stone, Meredith L, Herrera, Veronica M, Li, Yan, Coho, Heather, Xue, Yuqing, Graham, Kathleen, Ratmansky, Jennifer, Delman, Devora, O'Brien, Shaun, Beatty, Gregory L · 2025 · Cancer immunology research · DOI

Full title: Nonredundant Immune Checkpoints Direct Therapeutic Resistance to Chemoimmunotherapy in Pancreatic Ductal Adenocarcinoma.

Authors: Stone, Meredith L, Herrera, Veronica M, Li, Yan, Coho, Heather, Xue, Yuqing, Graham, Kathleen, Ratmansky, Jennifer, Delman, Devora, O'Brien, Shaun, Beatty, Gregory L

Year: 2025

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-25-0575

Paper Current trends in the treatment of malignant melanoma

Valko-Rokytovská, Marcela, BRUCHATA, K., Šimková, Jana, Milkovičová, Mária, Kostecká, Zuzana · 2016 · Neoplasma · DOI

Full title: Current trends in the treatment of malignant melanoma

Authors: Valko-Rokytovská, Marcela, BRUCHATA, K., Šimková, Jana, Milkovičová, Mária, Kostecká, Zuzana

Year: 2016

Venue: Neoplasma

DOI: https://doi.org/10.4149/301_151015n533

Paper Current and future drug combination strategies based on programmed death-1/programmed death-ligand 1 inhibitors in non-small cell lung cancer.

Cheng, Ying, Li, Hui, Zhang, Liang, Liu, Jing-Jing, Yang, Chang-Liang, Zhang, Shuang · 2021 · Chinese medical journal · DOI

Full title: Current and future drug combination strategies based on programmed death-1/programmed death-ligand 1 inhibitors in non-small cell lung cancer.

Authors: Cheng, Ying, Li, Hui, Zhang, Liang, Liu, Jing-Jing, Yang, Chang-Liang, Zhang, Shuang

Year: 2021

Venue: Chinese medical journal

DOI: https://doi.org/10.1097/CM9.0000000000001560

Paper Clinical outcomes of PD-1/PD-L1 inhibitors in patients with advanced hepatocellular carcinoma: a systematic review and meta-analysis.

Wen, Wen, Zhang, Yong, Zhang, Hua, Chen, Yingshuang · 2023 · Journal of cancer research and clinical oncology · DOI

Full title: Clinical outcomes of PD-1/PD-L1 inhibitors in patients with advanced hepatocellular carcinoma: a systematic review and meta-analysis.

Authors: Wen, Wen, Zhang, Yong, Zhang, Hua, Chen, Yingshuang

Year: 2023

Venue: Journal of cancer research and clinical oncology

DOI: https://doi.org/10.1007/s00432-022-04057-3

Paper Abstract CT180: Safety and efficacy of vibostolimab (vibo) plus pembrolizumab (pembro) and coformulation of vibo/pembro in ovarian cancer naive to PD-1/PD-L1 inhibitors

Ruth Perets, M. Gutierrez, S. Rha, Sarah Taylor, Brian Stein, Antonio Jimeno, I. Winer, Diana Chen, T. Keenan, M. Rajasagi, Mallika Lala, J. Healy, R. Shapira-Frommer · 2022 · Cancer Research · DOI

Full title: Abstract CT180: Safety and efficacy of vibostolimab (vibo) plus pembrolizumab (pembro) and coformulation of vibo/pembro in ovarian cancer naive to PD-1/PD-L1 inhibitors

Authors: Ruth Perets, M. Gutierrez, S. Rha, Sarah Taylor, Brian Stein, Antonio Jimeno, I. Winer, Diana Chen, T. Keenan, M. Rajasagi, Mallika Lala, J. Healy, R. Shapira-Frommer

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2022-ct180

Paper Risk of Immune-Related Pneumonitis with PD-1/PD-L1 Inhibitors in Different Cancer Types and Treatment Regimens: A Systematic Review and Meta-Analysis of 22 Randomized Controlled Trials.

Han, Lei, Li, Guangxin, Li, Huihui, Zhao, Lei · 2023 · Chemotherapy · DOI

Full title: Risk of Immune-Related Pneumonitis with PD-1/PD-L1 Inhibitors in Different Cancer Types and Treatment Regimens: A Systematic Review and Meta-Analysis of 22 Randomized Controlled Trials.

Authors: Han, Lei, Li, Guangxin, Li, Huihui, Zhao, Lei

Year: 2023

Venue: Chemotherapy

DOI: https://doi.org/10.1159/000523904

Paper Circulating tumour DNA kinetics in recurrent/metastatic head and neck squamous cell cancer patients.

Kirsty Taylor, Jinfeng Zou, Marcos Magalhaes, M. Oliva, A. Spreafico, A. Hansen, S. McDade, V. Coyle, M. Lawler, E. Elimova, S. Bratman, L. Siu · 2023 · European Journal of Cancer · DOI

Full title: Circulating tumour DNA kinetics in recurrent/metastatic head and neck squamous cell cancer patients.

Authors: Kirsty Taylor, Jinfeng Zou, Marcos Magalhaes, M. Oliva, A. Spreafico, A. Hansen, S. McDade, V. Coyle, M. Lawler, E. Elimova, S. Bratman, L. Siu

Year: 2023

Venue: European Journal of Cancer

DOI: https://doi.org/10.1016/j.ejca.2023.04.014

Paper A phase III study (COSMIC-313) of cabozantinib (C) in combination with nivolumab (N) and ipilimumab (I) in patients (pts) with previously untreated advanced renal cell carcinoma (aRCC) of intermediate or poor risk.

T. Choueiri, L. Albiges, T. Powles, C. Scheffold, Fong Wang, R. Motzer · 2020 · Journal of Clinical Oncology · DOI

Full title: A phase III study (COSMIC-313) of cabozantinib (C) in combination with nivolumab (N) and ipilimumab (I) in patients (pts) with previously untreated advanced renal cell carcinoma (aRCC) of intermediate or poor risk.

Authors: T. Choueiri, L. Albiges, T. Powles, C. Scheffold, Fong Wang, R. Motzer

Year: 2020

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2020.38.6_suppl.tps767

Paper SP6.1.4 Novel methods to enhance anti-tumour immunity in oesophageal adenocarcinoma; hypofractionated radiotherapy may be superior to CROSS regimen chemo-radiation

N. Donlon, M. Davern, A. Sheppard, C. Donohoe, J. Reynolds, J. Lysaght · 2022 · British Journal of Surgery · DOI

Full title: SP6.1.4 Novel methods to enhance anti-tumour immunity in oesophageal adenocarcinoma; hypofractionated radiotherapy may be superior to CROSS regimen chemo-radiation

Authors: N. Donlon, M. Davern, A. Sheppard, C. Donohoe, J. Reynolds, J. Lysaght

Year: 2022

Venue: British Journal of Surgery

DOI: https://doi.org/10.1093/bjs/znac247.064

Paper Overcoming toxicity challenges in immune checkpoint inhibitor treatment of high-risk metastatic cancers.

Nalabothu, Rishitha, Johnson, Douglas B · 2025 · Expert review of anticancer therapy · DOI

Full title: Overcoming toxicity challenges in immune checkpoint inhibitor treatment of high-risk metastatic cancers.

Authors: Nalabothu, Rishitha, Johnson, Douglas B

Year: 2025

Venue: Expert review of anticancer therapy

DOI: https://doi.org/10.1080/14737140.2025.2599891

Paper Targeted Therapy and Immunotherapy in Melanoma.

Lazaroff, Jake, Bolotin, Diana · 2023 · Dermatologic clinics · DOI

Full title: Targeted Therapy and Immunotherapy in Melanoma.

Authors: Lazaroff, Jake, Bolotin, Diana

Year: 2023

Venue: Dermatologic clinics

DOI: https://doi.org/10.1016/j.det.2022.07.007

Paper Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who May Benefit from Combination Immunotherapy.

Marsavela, Gabriela, Lee, Jenny, Calapre, Leslie, Wong, Stephen Q, Pereira, Michelle R, McEvoy, Ashleigh C, Reid, Anna L, Robinson, Cleo, Warburton, Lydia, Abed, Afaf, Khattak, Muhammad A, Meniawy, Tarek M, Dawson, Sarah-Jane, Sandhu, Shahneen, Carlino, Matteo S, Menzies, Alexander M, Scolyer, Richard A, Long, Georgina V, Amanuel, Benhur, Millward, Michael, Ziman, Melanie R, Rizos, Helen, Gray, Elin S · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who May Benefit from Combination Immunotherapy.

Authors: Marsavela, Gabriela, Lee, Jenny, Calapre, Leslie, Wong, Stephen Q, Pereira, Michelle R, McEvoy, Ashleigh C, Reid, Anna L, Robinson, Cleo, Warburton, Lydia, Abed, Afaf, Khattak, Muhammad A, Meniawy, Tarek M, Dawson, Sarah-Jane, Sandhu, Shahneen, Carlino, Matteo S, Menzies, Alexander M, Scolyer, Richard A, Long, Georgina V, Amanuel, Benhur, Millward, Michael, Ziman, Melanie R, Rizos, Helen, Gray, Elin S

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2251

Paper TIM‐3 expression induces resistance to PD‐1 inhibitor in G‐CSF‐producing lung spindle cell carcinoma: A case report

Fumiko Hayashi, K. Akagi, Hirokazu Taniguchi, T. Matsutake, Hiromi Kawahara, Ichiro Sekine, H. Gyotoku, S. Takemoto, Hiroshi Soda, Kazuto Ashizawa, H. Mukae · 2023 · Thoracic Cancer · DOI

Full title: TIM‐3 expression induces resistance to PD‐1 inhibitor in G‐CSF‐producing lung spindle cell carcinoma: A case report

Authors: Fumiko Hayashi, K. Akagi, Hirokazu Taniguchi, T. Matsutake, Hiromi Kawahara, Ichiro Sekine, H. Gyotoku, S. Takemoto, Hiroshi Soda, Kazuto Ashizawa, H. Mukae

Year: 2023

Venue: Thoracic Cancer

DOI: https://doi.org/10.1111/1759-7714.15149

Paper NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021

Ettinger, David S., Wood, Douglas E., Aisner, Dara L., Akerley, Wallace, Bauman, Jessica R., Bharat, Ankit, Bruno, Débora S., Chang, Joe Y., Chirieac, Lucian R., D’Amico, Thomas A., Dilling, Thomas J., Dowell, Jonathan E., Gettinger, Scott, Gubens, Matthew A., Hegde, Aparna, Hennon, Mark, Lackner, Rudy P., Lanuti, Michael, Leal, Ticiana, Lin, Jules, Loo, Billy W., Lovly, Christine M., Martins, Renato, Massarelli, Erminia, Morgensztern, Daniel, Ng, Thomas, Otterson, Gregory A., Patel, Sandip Pravin, Riely, Gregory J., Schild, Steven E., Shapiro, Theresa A., Singh, Aditi P., Stevenson, James, Tam, Alda L., Yanagawa, Jane, Yang, Stephen C., Gregory, Kristina M., Hughes, Miranda · 2021 · Journal of the National Comprehensive Cancer Network · DOI

Full title: NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021

Authors: Ettinger, David S., Wood, Douglas E., Aisner, Dara L., Akerley, Wallace, Bauman, Jessica R., Bharat, Ankit, Bruno, Débora S., Chang, Joe Y., Chirieac, Lucian R., D’Amico, Thomas A., Dilling, Thomas J., Dowell, Jonathan E., Gettinger, Scott, Gubens, Matthew A., Hegde, Aparna, Hennon, Mark, Lackner, Rudy P., Lanuti, Michael, Leal, Ticiana, Lin, Jules, Loo, Billy W., Lovly, Christine M., Martins, Renato, Massarelli, Erminia, Morgensztern, Daniel, Ng, Thomas, Otterson, Gregory A., Patel, Sandip Pravin, Riely, Gregory J., Schild, Steven E., Shapiro, Theresa A., Singh, Aditi P., Stevenson, James, Tam, Alda L., Yanagawa, Jane, Yang, Stephen C., Gregory, Kristina M., Hughes, Miranda

Year: 2021

Venue: Journal of the National Comprehensive Cancer Network

DOI: https://doi.org/10.6004/jnccn.2021.0013

Paper Combination immunotherapy strategies for glioblastoma.

Chan, Hok Yee, Choi, John, Jackson, Christina, Lim, Michael · 2021 · Journal of neuro-oncology · DOI

Full title: Combination immunotherapy strategies for glioblastoma.

Authors: Chan, Hok Yee, Choi, John, Jackson, Christina, Lim, Michael

Year: 2021

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-020-03481-0

Paper Short-term CTLA-4 blockade directly followed by PD-1 blockade in advanced melanoma patients: a single-center experience.

Meerveld-Eggink, A, Rozeman, E A, Lalezari, F, van Thienen, J V, Haanen, J B A G, Blank, C U · 2017 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Short-term CTLA-4 blockade directly followed by PD-1 blockade in advanced melanoma patients: a single-center experience.

Authors: Meerveld-Eggink, A, Rozeman, E A, Lalezari, F, van Thienen, J V, Haanen, J B A G, Blank, C U

Year: 2017

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdw692

Paper Network meta-analysis of first-line systemic regimens for older patients with advanced NSCLC.

Luciani, Andrea, Dottorini, Lorenzo, Battaiotto, Elena, Petrelli, Fausto · 2024 · Anti-cancer drugs · DOI

Full title: Network meta-analysis of first-line systemic regimens for older patients with advanced NSCLC.

Authors: Luciani, Andrea, Dottorini, Lorenzo, Battaiotto, Elena, Petrelli, Fausto

Year: 2024

Venue: Anti-cancer drugs

DOI: https://doi.org/10.1097/CAD.0000000000001602

Paper Emerging first line treatment options for bladder cancer: a review of phase II and III therapies in the pipeline.

Jamy, Omer, Sonpavde, Guru · 2017 · Expert opinion on emerging drugs · DOI

Full title: Emerging first line treatment options for bladder cancer: a review of phase II and III therapies in the pipeline.

Authors: Jamy, Omer, Sonpavde, Guru

Year: 2017

Venue: Expert opinion on emerging drugs

DOI: https://doi.org/10.1080/14728214.2017.1416092

Paper Dermatologic toxicity from immune checkpoint blockade therapy with an interstitial granulomatous pattern

Trinidad, Celestine, Nelson, Kelly C., Oliva, Isabella C. Glitza, Torres‐Cabala, Carlos A., Nagarajan, Priyadharsini, Tetzlaff, Michael T., Ivan, Doina, Hwu, Wen‐Jen, Prieto, Víctor G., Curry, Jonathan L., Aung, Phyu P. · 2018 · Journal of Cutaneous Pathology · DOI

Full title: Dermatologic toxicity from immune checkpoint blockade therapy with an interstitial granulomatous pattern

Authors: Trinidad, Celestine, Nelson, Kelly C., Oliva, Isabella C. Glitza, Torres‐Cabala, Carlos A., Nagarajan, Priyadharsini, Tetzlaff, Michael T., Ivan, Doina, Hwu, Wen‐Jen, Prieto, Víctor G., Curry, Jonathan L., Aung, Phyu P.

Year: 2018

Venue: Journal of Cutaneous Pathology

DOI: https://doi.org/10.1111/cup.13150

Paper Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization.

Rausch, Johanna, Lopez, Pamela Aranda, Bialojan, Ariane, Denny, Mark, Langguth, Peter, Probst, Hans Christian, Schild, Hansjörg, Radsak, Markus P · 2017 · Journal of dermatological science · DOI

Full title: Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization.

Authors: Rausch, Johanna, Lopez, Pamela Aranda, Bialojan, Ariane, Denny, Mark, Langguth, Peter, Probst, Hans Christian, Schild, Hansjörg, Radsak, Markus P

Year: 2017

Venue: Journal of dermatological science

DOI: https://doi.org/10.1016/j.jdermsci.2017.06.013

Paper Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.

Grünenfelder, Denise C, Velaparthi, Upender, Warrier, Jayakumar S, Chupak, Louis, Darne, Chetan Padmakar, Dasgupta, Bireshwar, Dhar, T G Murali, Ding, Min, Gentles, Robert, Huang, Yazhong, Jalagam, Prasada R, Kamble, Manjunatha Narayana Rao, Mannoori, Raju, Martin, Scott, Posy, Shana L, Rahaman, Hasibur, Raja, Thiruvenkadam, Reddy, Kotha Rathnakar, Roy, Saumya, Sarjeant, Amy, Tokarski, John S, Tonukunuru, Gopikishan, Velaiah, Sivasudar, Zheng, Xiaofan, Anandam, Aravind, Dhar, Gopal, Dudhgaonkar, Shailesh, Fancher, R Marcus, Layane, Siddheshwar, Liu, Si-Qi, Ray, Swagatam, Qiu, Hongchen, Wee, Susan, Chatterjee, Sagnik, Davis, Myrtle, Dierks, Elizabeth, Kumar, Anoop, Mariappan, Thanga, Moore, Robin, Murali, Bokka Venkata, Sane, Ramola, Banas, Dana, Calambur, Deepa, Cook, Erica, Dehal, Priya, Fang, Hua, Locke, Gregory, Naglich, Joseph G, Ravindran, Madhu Sudhan, Schneeweis, Lumelle, Tagore, Debarati M, Witmer, Mark, Witt, Abigail E, Xie, Dianlin, Lees, Emma, Wichroski, Michael, Meanwell, Nicholas A, Borzilleri, Robert, Olson, Richard E · 2025 · Journal of medicinal chemistry · DOI

Full title: Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.

Authors: Grünenfelder, Denise C, Velaparthi, Upender, Warrier, Jayakumar S, Chupak, Louis, Darne, Chetan Padmakar, Dasgupta, Bireshwar, Dhar, T G Murali, Ding, Min, Gentles, Robert, Huang, Yazhong, Jalagam, Prasada R, Kamble, Manjunatha Narayana Rao, Mannoori, Raju, Martin, Scott, Posy, Shana L, Rahaman, Hasibur, Raja, Thiruvenkadam, Reddy, Kotha Rathnakar, Roy, Saumya, Sarjeant, Amy, Tokarski, John S, Tonukunuru, Gopikishan, Velaiah, Sivasudar, Zheng, Xiaofan, Anandam, Aravind, Dhar, Gopal, Dudhgaonkar, Shailesh, Fancher, R Marcus, Layane, Siddheshwar, Liu, Si-Qi, Ray, Swagatam, Qiu, Hongchen, Wee, Susan, Chatterjee, Sagnik, Davis, Myrtle, Dierks, Elizabeth, Kumar, Anoop, Mariappan, Thanga, Moore, Robin, Murali, Bokka Venkata, Sane, Ramola, Banas, Dana, Calambur, Deepa, Cook, Erica, Dehal, Priya, Fang, Hua, Locke, Gregory, Naglich, Joseph G, Ravindran, Madhu Sudhan, Schneeweis, Lumelle, Tagore, Debarati M, Witmer, Mark, Witt, Abigail E, Xie, Dianlin, Lees, Emma, Wichroski, Michael, Meanwell, Nicholas A, Borzilleri, Robert, Olson, Richard E

Year: 2025

Venue: Journal of medicinal chemistry

DOI: https://doi.org/10.1021/acs.jmedchem.5c02240

Paper A meta-analysis of application of PD-1/PD-L1 inhibitor-based immunotherapy in unresectable locally advanced triple-negative breast cancer.

Zhang, Wei, He, Yujing, Tang, Yuning, Dai, Wei, Si, Yuexiu, Mao, Feiyan, Xu, Jiaxuan, Yu, Chiyuan, Sun, Xing · 2023 · Immunotherapy · DOI

Full title: A meta-analysis of application of PD-1/PD-L1 inhibitor-based immunotherapy in unresectable locally advanced triple-negative breast cancer.

Authors: Zhang, Wei, He, Yujing, Tang, Yuning, Dai, Wei, Si, Yuexiu, Mao, Feiyan, Xu, Jiaxuan, Yu, Chiyuan, Sun, Xing

Year: 2023

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2023-0023

Paper NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer.

Messersmith, Wells A · 2019 · Journal of the National Comprehensive Cancer Network : JNCCN · DOI

Full title: NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer.

Authors: Messersmith, Wells A

Year: 2019

Venue: Journal of the National Comprehensive Cancer Network : JNCCN

DOI: https://doi.org/10.6004/jnccn.2019.5014

Paper Development of immunotherapy in bladder cancer: present and future on targeting PD(L)1 and CTLA-4 pathways.

Rouanne, Mathieu, Roumiguié, Mathieu, Houédé, Nadine, Masson-Lecomte, Alexandra, Colin, Pierre, Pignot, Géraldine, Larré, Stéphane, Xylinas, Evanguelos, Rouprêt, Morgan, Neuzillet, Yann · 2018 · World journal of urology · DOI

Full title: Development of immunotherapy in bladder cancer: present and future on targeting PD(L)1 and CTLA-4 pathways.

Authors: Rouanne, Mathieu, Roumiguié, Mathieu, Houédé, Nadine, Masson-Lecomte, Alexandra, Colin, Pierre, Pignot, Géraldine, Larré, Stéphane, Xylinas, Evanguelos, Rouprêt, Morgan, Neuzillet, Yann

Year: 2018

Venue: World journal of urology

DOI: https://doi.org/10.1007/s00345-018-2332-5

Paper PD-1 Inhibitors: Do they have a Future in the Treatment of Glioblastoma?

Khasraw, Mustafa, Reardon, David A, Weller, Michael, Sampson, John H · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: PD-1 Inhibitors: Do they have a Future in the Treatment of Glioblastoma?

Authors: Khasraw, Mustafa, Reardon, David A, Weller, Michael, Sampson, John H

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-20-1135

Paper Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence.

Adrianzen Herrera, Diego, Ashai, Nadia, Perez-Soler, Roman, Cheng, Haiying · 2019 · Expert opinion on pharmacotherapy · DOI

Full title: Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence.

Authors: Adrianzen Herrera, Diego, Ashai, Nadia, Perez-Soler, Roman, Cheng, Haiying

Year: 2019

Venue: Expert opinion on pharmacotherapy

DOI: https://doi.org/10.1080/14656566.2018.1546290

Paper Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer.

van Hooren, Luuk, Sandin, Linda C, Moskalev, Igor, Ellmark, Peter, Dimberg, Anna, Black, Peter, Tötterman, Thomas H, Mangsbo, Sara M · 2017 · European journal of immunology · DOI

Full title: Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer.

Authors: van Hooren, Luuk, Sandin, Linda C, Moskalev, Igor, Ellmark, Peter, Dimberg, Anna, Black, Peter, Tötterman, Thomas H, Mangsbo, Sara M

Year: 2017

Venue: European journal of immunology

DOI: https://doi.org/10.1002/eji.201646583

Paper MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a retrospective multicentre analysis of 364 patients.

Kirchberger, Michael Constantin, Ugurel, Selma, Mangana, Johanna, Heppt, Markus Valentin, Eigentler, Thomas Kurt, Berking, Carola, Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard, Heinzerling, Lucie · 2018 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a retrospective multicentre analysis of 364 patients.

Authors: Kirchberger, Michael Constantin, Ugurel, Selma, Mangana, Johanna, Heppt, Markus Valentin, Eigentler, Thomas Kurt, Berking, Carola, Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard, Heinzerling, Lucie

Year: 2018

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2018.04.010

Paper A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma.

Wang, Qian, Li, Xiangmei, Qiu, Jiayue, He, Yalan, Wu, Jiashuo, Li, Ji, Liu, Wei, Han, Junwei · 2023 · Computational and structural biotechnology journal · DOI

Full title: A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma.

Authors: Wang, Qian, Li, Xiangmei, Qiu, Jiayue, He, Yalan, Wu, Jiashuo, Li, Ji, Liu, Wei, Han, Junwei

Year: 2023

Venue: Computational and structural biotechnology journal

DOI: https://doi.org/10.1016/j.csbj.2023.04.004

Paper PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis

Schneider, Stephanie, Potthast, Silke, Komminoth, Paul, Schwegler, Guido, Böhm, Steffen · 2017 · Case Reports in Oncology · DOI

Full title: PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis

Authors: Schneider, Stephanie, Potthast, Silke, Komminoth, Paul, Schwegler, Guido, Böhm, Steffen

Year: 2017

Venue: Case Reports in Oncology

DOI: https://doi.org/10.1159/000477162

Paper An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model.

Kitagawa, Koichi, Tatsumi, Maho, Kato, Mako, Komai, Shota, Doi, Hazuki, Hashii, Yoshiko, Katayama, Takane, Fujisawa, Masato, Shirakawa, Toshiro · 2021 · Molecular therapy oncolytics · DOI

Full title: An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model.

Authors: Kitagawa, Koichi, Tatsumi, Maho, Kato, Mako, Komai, Shota, Doi, Hazuki, Hashii, Yoshiko, Katayama, Takane, Fujisawa, Masato, Shirakawa, Toshiro

Year: 2021

Venue: Molecular therapy oncolytics

DOI: https://doi.org/10.1016/j.omto.2021.08.009

Paper Radiotherapy and immunology.

Wang, Liangliang, Lynch, Connor, Pitroda, Sean P, Piffkó, András, Yang, Kaiting, Huser, Amy K, Liang, Hua Laura, Weichselbaum, Ralph R · 2024 · The Journal of experimental medicine · DOI

Full title: Radiotherapy and immunology.

Authors: Wang, Liangliang, Lynch, Connor, Pitroda, Sean P, Piffkó, András, Yang, Kaiting, Huser, Amy K, Liang, Hua Laura, Weichselbaum, Ralph R

Year: 2024

Venue: The Journal of experimental medicine

DOI: https://doi.org/10.1084/jem.20232101

Paper Cationic Peptide Conjugation Enhances Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies.

Mohanty, Rashmi P, Pan, Yuting, Lewis, Mae M, Soto, Melissa R, Maier, Esther Y, Alzhrani, Riyad F, Ghosh, Debadyuti · 2025 · Bioconjugate chemistry · DOI

Full title: Cationic Peptide Conjugation Enhances Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies.

Authors: Mohanty, Rashmi P, Pan, Yuting, Lewis, Mae M, Soto, Melissa R, Maier, Esther Y, Alzhrani, Riyad F, Ghosh, Debadyuti

Year: 2025

Venue: Bioconjugate chemistry

DOI: https://doi.org/10.1021/acs.bioconjchem.5c00257

Paper Pembrolizumab in mCRPC - Combination therapies as breakthrough to success?

Plas, Stefan, Pircher, Andreas, Heidegger, Isabel · 2023 · Current opinion in urology · DOI

Full title: Pembrolizumab in mCRPC - Combination therapies as breakthrough to success?

Authors: Plas, Stefan, Pircher, Andreas, Heidegger, Isabel

Year: 2023

Venue: Current opinion in urology

DOI: https://doi.org/10.1097/MOU.0000000000001121

Paper ESIRA, a novel framework integrating efficacy and safety for evaluating first-line treatments in advanced hepatocellular carcinoma.

Li, Hai-Long, Zhou, Hui, Zhang, Yi-Yang, Lai, Jin-Ting, Zhou, Zhen-Zhong, Huang, Jing-Yi, Guo, Song-Bin, Wang, Yu, Huang, Wei-Juan, Tian, Xiao-Peng · 2026 · Science China. Life sciences · DOI

Full title: ESIRA, a novel framework integrating efficacy and safety for evaluating first-line treatments in advanced hepatocellular carcinoma.

Authors: Li, Hai-Long, Zhou, Hui, Zhang, Yi-Yang, Lai, Jin-Ting, Zhou, Zhen-Zhong, Huang, Jing-Yi, Guo, Song-Bin, Wang, Yu, Huang, Wei-Juan, Tian, Xiao-Peng

Year: 2026

Venue: Science China. Life sciences

DOI: https://doi.org/10.1007/s11427-025-3093-8

Paper Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to nivolumab plus ipilimumab.

Fuchizawa, Hirotaka, Kijima, Toshiki, Takada-Owada, Atsuko, Nagashima, Yoji, Okazaki, Akihito, Yokoyama, Megumi, Nishihara, Daisaku, Ishida, Kazuyuki, Kamai, Takao · 2021 · IJU case reports · DOI

Full title: Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to nivolumab plus ipilimumab.

Authors: Fuchizawa, Hirotaka, Kijima, Toshiki, Takada-Owada, Atsuko, Nagashima, Yoji, Okazaki, Akihito, Yokoyama, Megumi, Nishihara, Daisaku, Ishida, Kazuyuki, Kamai, Takao

Year: 2021

Venue: IJU case reports

DOI: https://doi.org/10.1002/iju5.12342

Paper Conception and viable twin pregnancy in a patient with metastatic melanoma while treated with CTLA-4 and PD-1 checkpoint inhibition.

Bucheit, Amanda D, Hardy, John T, Szender, J Brian, Glitza Oliva, Isabella C · 2020 · Melanoma research · DOI

Full title: Conception and viable twin pregnancy in a patient with metastatic melanoma while treated with CTLA-4 and PD-1 checkpoint inhibition.

Authors: Bucheit, Amanda D, Hardy, John T, Szender, J Brian, Glitza Oliva, Isabella C

Year: 2020

Venue: Melanoma research

DOI: https://doi.org/10.1097/CMR.0000000000000657

Paper Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control.

Sanseviero, Emilio, O'Brien, Erin M, Karras, Jenna R, Shabaneh, Tamer B, Aksoy, Bulent Arman, Xu, Wei, Zheng, Cathy, Yin, Xiangfan, Xu, Xiaowei, Karakousis, Giorgos C, Amaravadi, Ravi K, Nam, Brian, Turk, Mary Jo, Hammerbacher, Jeff, Rubinstein, Mark P, Schuchter, Lynn M, Mitchell, Tara C, Liu, Qin, Stone, Erica L · 2019 · Cancer immunology research · DOI

Full title: Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control.

Authors: Sanseviero, Emilio, O'Brien, Erin M, Karras, Jenna R, Shabaneh, Tamer B, Aksoy, Bulent Arman, Xu, Wei, Zheng, Cathy, Yin, Xiangfan, Xu, Xiaowei, Karakousis, Giorgos C, Amaravadi, Ravi K, Nam, Brian, Turk, Mary Jo, Hammerbacher, Jeff, Rubinstein, Mark P, Schuchter, Lynn M, Mitchell, Tara C, Liu, Qin, Stone, Erica L

Year: 2019

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0386

Paper Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.

Inozume, Takashi, Namikawa, Kenjiro, Kato, Hiroshi, Yoshikawa, Shusuke, Kiniwa, Yukiko, Yoshino, Koji, Mizuhashi, Satoru, Ito, Takamichi, Takenouchi, Tatsuya, Matsushita, Shigeto, Fujisawa, Yasuhiro, Matsuzawa, Takamitsu, Sugihara, Satoru, Asai, Jun, Kitagawa, Hiroshi, Maekawa, Takeo, Isei, Taiki, Yasuda, Masahito, Yamazaki, Naoya, Uhara, Hisashi, Nakamura, Yasuhiro · 2023 · Journal of dermatological science · DOI

Full title: Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.

Authors: Inozume, Takashi, Namikawa, Kenjiro, Kato, Hiroshi, Yoshikawa, Shusuke, Kiniwa, Yukiko, Yoshino, Koji, Mizuhashi, Satoru, Ito, Takamichi, Takenouchi, Tatsuya, Matsushita, Shigeto, Fujisawa, Yasuhiro, Matsuzawa, Takamitsu, Sugihara, Satoru, Asai, Jun, Kitagawa, Hiroshi, Maekawa, Takeo, Isei, Taiki, Yasuda, Masahito, Yamazaki, Naoya, Uhara, Hisashi, Nakamura, Yasuhiro

Year: 2023

Venue: Journal of dermatological science

DOI: https://doi.org/10.1016/j.jdermsci.2023.03.008

Paper Efficacy of immune checkpoint inhibitors for in-transit melanoma.

Nan Tie, Emilia, Lai-Kwon, Julia, Rtshiladze, Michael Alexander, Na, Lumine, Bozzi, James, Read, Tavis, Atkinson, Victoria, Au-Yeung, George, Long, Georgina V, McArthur, Grant A, Sandhu, Shahneen, Saw, Robyn, Walpole, Euan, Menzies, Alexander, Smithers, Mark, Gyorki, David E · 2020 · Journal for immunotherapy of cancer · DOI

Full title: Efficacy of immune checkpoint inhibitors for in-transit melanoma.

Authors: Nan Tie, Emilia, Lai-Kwon, Julia, Rtshiladze, Michael Alexander, Na, Lumine, Bozzi, James, Read, Tavis, Atkinson, Victoria, Au-Yeung, George, Long, Georgina V, McArthur, Grant A, Sandhu, Shahneen, Saw, Robyn, Walpole, Euan, Menzies, Alexander, Smithers, Mark, Gyorki, David E

Year: 2020

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2019-000440

Paper Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.

Full title: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.

Year: 2016

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0161779

Paper Mechanisms of targeting cd28 by a signaling monoclonal antibody in acute and chronic allograft rejection1

Dong, Victor, Yuan, Xueli, Coito, Ana J., Waaga, Ana Maria, Sayegh, Mohamed H., Chandraker, Anil · 2002 · Transplantation · DOI

Full title: Mechanisms of targeting cd28 by a signaling monoclonal antibody in acute and chronic allograft rejection1

Authors: Dong, Victor, Yuan, Xueli, Coito, Ana J., Waaga, Ana Maria, Sayegh, Mohamed H., Chandraker, Anil

Year: 2002

Venue: Transplantation

DOI: https://doi.org/10.1097/00007890-200204270-00021

Paper Efficacy and safety of personalized optimal PD-(L)1 combinations in advanced NSCLC: a network meta-analysis

Chu, Xianjing, Tian, Wentao, Ning, Jiaoyang, Zhou, Rongrong · 2024 · JNCI Journal of the National Cancer Institute · DOI

Full title: Efficacy and safety of personalized optimal PD-(L)1 combinations in advanced NSCLC: a network meta-analysis

Authors: Chu, Xianjing, Tian, Wentao, Ning, Jiaoyang, Zhou, Rongrong

Year: 2024

Venue: JNCI Journal of the National Cancer Institute

DOI: https://doi.org/10.1093/jnci/djae137

Paper Site-Dependent Immune Escape Due to Impaired Dendritic Cell Cross-Priming

Diamond, Mark S., Lin, Jeffrey, Vonderheide, Robert H. · 2021 · Cancer Immunology Research · DOI

Full title: Site-Dependent Immune Escape Due to Impaired Dendritic Cell Cross-Priming

Authors: Diamond, Mark S., Lin, Jeffrey, Vonderheide, Robert H.

Year: 2021

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-20-0785

Paper Reviewer #3 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: Reviewer #3 (Public Review): DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2.sa0

Paper Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein ligand-1.

Zhao, Jing, Huang, Jian · 2020 · Chinese medical journal · DOI

Full title: Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein ligand-1.

Authors: Zhao, Jing, Huang, Jian

Year: 2020

Venue: Chinese medical journal

DOI: https://doi.org/10.1097/CM9.0000000000000710

Paper SAT-239 Combination of Immune Check Point Inhibitors Causing Hypopituitarism

P. Dhillon, Harshwant Grover, Jonathan Slusser, Neethu Gopisetti, Tirth Patel · 2020 · Journal of the Endocrine Society · DOI

Full title: SAT-239 Combination of Immune Check Point Inhibitors Causing Hypopituitarism

Authors: P. Dhillon, Harshwant Grover, Jonathan Slusser, Neethu Gopisetti, Tirth Patel

Year: 2020

Venue: Journal of the Endocrine Society

DOI: https://doi.org/10.1210/jendso/bvaa046.1107

Paper Oncolytic viruses as engineering platforms for combination immunotherapy.

Twumasi-Boateng, Kwame, Pettigrew, Jessica L, Kwok, Y Y Eunice, Bell, John C, Nelson, Brad H · 2018 · Nature reviews. Cancer · DOI

Full title: Oncolytic viruses as engineering platforms for combination immunotherapy.

Authors: Twumasi-Boateng, Kwame, Pettigrew, Jessica L, Kwok, Y Y Eunice, Bell, John C, Nelson, Brad H

Year: 2018

Venue: Nature reviews. Cancer

DOI: https://doi.org/10.1038/s41568-018-0009-4

Paper Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy.

Waitz, Rebecca, Solomon, Stephen B, Petre, Elena N, Trumble, Anne E, Fassò, Marcella, Norton, Larry, Allison, James P · 2012 · Cancer research · DOI

Full title: Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy.

Authors: Waitz, Rebecca, Solomon, Stephen B, Petre, Elena N, Trumble, Anne E, Fassò, Marcella, Norton, Larry, Allison, James P

Year: 2012

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-11-1782

Paper Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma receiving first-line combination immunotherapies: results from the International Metastatic Renal Cell Carcinoma Database Consortium

Takemura, Kosuke, Yuasa, T, Lemelin, A, Ferrier, E, Wells, J. Connor, Saad, Ehab, Saliby, R.M., Basappa, Naveen S., Wood, L A, Jude, E, Pal, Sumanta K., Donskov, F, Beuselinck, B, Szabados, B, Powles, T, McKay, Rana R., Gebrael, Georges, Agarwal, N, Choueiri, Toni K., Heng, D Y C · 2024 · ESMO Open · DOI

Full title: Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma receiving first-line combination immunotherapies: results from the International Metastatic Renal Cell Carcinoma Database Consortium

Authors: Takemura, Kosuke, Yuasa, T, Lemelin, A, Ferrier, E, Wells, J. Connor, Saad, Ehab, Saliby, R.M., Basappa, Naveen S., Wood, L A, Jude, E, Pal, Sumanta K., Donskov, F, Beuselinck, B, Szabados, B, Powles, T, McKay, Rana R., Gebrael, Georges, Agarwal, N, Choueiri, Toni K., Heng, D Y C

Year: 2024

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2024.103606

Paper Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer.

Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou · 2023 · Cancer research · DOI

Full title: Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer.

Authors: Cao, Kankan, Zhang, Guodong, Yang, Moran, Wang, Yiying, He, Mengdi, Zhang, Chen, Huang, Yan, Lu, Jiaqi, Liu, Haiou

Year: 2023

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-22-3260

Paper DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Nick Mullen, Surendra K. Shukla, Ravi Thakur, S. S. Kollala, Dezhen Wang, Nina V. Chaika, Juan F Santana, William R Miklavcic, Drew A. LaBreck, J. Mallareddy, David H. Price, A. Natarajan, Kamiya Mehla, David B. Sykes, Michael A. Hollingsworth, Pankaj K. Singh · 2024 · eLife · DOI

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: Nick Mullen, Surendra K. Shukla, Ravi Thakur, S. S. Kollala, Dezhen Wang, Nina V. Chaika, Juan F Santana, William R Miklavcic, Drew A. LaBreck, J. Mallareddy, David H. Price, A. Natarajan, Kamiya Mehla, David B. Sykes, Michael A. Hollingsworth, Pankaj K. Singh

Year: 2024

Venue: eLife

DOI: https://doi.org/10.7554/elife.87292

Paper The Efficacy and Safety of Pembrolizumab, Ipilimumab, and Nivolumab Monoteraphy and Combination for Colorectal Cancer: A Systematic Review and Meta-Analysis

A. A. Adrianto, I. Riwanto, U. Sadhana, D. K. Paramita, H. Setyawan, K. C. Tjandra, D. R. P. Respati, D. D. C. H. Rampengan, R. N. Ramadhan, G. G. Jangkang, E. Mahati · 2024 · medRxiv · DOI

Full title: The Efficacy and Safety of Pembrolizumab, Ipilimumab, and Nivolumab Monoteraphy and Combination for Colorectal Cancer: A Systematic Review and Meta-Analysis

Authors: A. A. Adrianto, I. Riwanto, U. Sadhana, D. K. Paramita, H. Setyawan, K. C. Tjandra, D. R. P. Respati, D. D. C. H. Rampengan, R. N. Ramadhan, G. G. Jangkang, E. Mahati

Year: 2024

Venue: medRxiv

DOI: https://doi.org/10.1101/2024.07.02.24309865

Paper Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC).

Chae, Young Kwang, Arya, Ayush, Iams, Wade, Cruz, Marcelo R, Chandra, Sunandana, Choi, Jaehyuk, Giles, Francis · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC).

Authors: Chae, Young Kwang, Arya, Ayush, Iams, Wade, Cruz, Marcelo R, Chandra, Sunandana, Choi, Jaehyuk, Giles, Francis

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0349-3

Paper Combining anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) and -programmed cell death protein 1 (PD-1) agents for cancer immunotherapy.

Wong, Selina K, Beckermann, Kathryn E, Johnson, Douglas B, Das, Satya · 2021 · Expert opinion on biological therapy · DOI

Full title: Combining anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) and -programmed cell death protein 1 (PD-1) agents for cancer immunotherapy.

Authors: Wong, Selina K, Beckermann, Kathryn E, Johnson, Douglas B, Das, Satya

Year: 2021

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2021.1921140

Paper Dual immune checkpoint inhibitors or combined with anti-VEGF agents in advanced, unresectable hepatocellular carcinoma.

Zhang, Bo, Tao, Baorui, Li, Yitong, Yi, Chenhe, Lin, Zhifei, Ma, Yue, Han, Jiahao, Shao, Weiqing, Chen, Zhenmei, Lin, Jing, Chen, Jinhong · 2023 · European journal of internal medicine · DOI

Full title: Dual immune checkpoint inhibitors or combined with anti-VEGF agents in advanced, unresectable hepatocellular carcinoma.

Authors: Zhang, Bo, Tao, Baorui, Li, Yitong, Yi, Chenhe, Lin, Zhifei, Ma, Yue, Han, Jiahao, Shao, Weiqing, Chen, Zhenmei, Lin, Jing, Chen, Jinhong

Year: 2023

Venue: European journal of internal medicine

DOI: https://doi.org/10.1016/j.ejim.2022.12.025

Paper ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement.

Riley, J L, Blair, P J, Musser, J T, Abe, R, Tezuka, K, Tsuji, T, June, C H · 2001 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement.

Authors: Riley, J L, Blair, P J, Musser, J T, Abe, R, Tezuka, K, Tsuji, T, June, C H

Year: 2001

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.166.8.4943

Paper Characteristics of the immune microenvironment associated with RRM2 expression and its application to PD-L1/PD-1 inhibitors in lung adenocarcinoma.

Lee, Seul-Ki, Hwang, Yoonjung, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo, Koh, Young Wha · 2023 · American journal of cancer research

Full title: Characteristics of the immune microenvironment associated with RRM2 expression and its application to PD-L1/PD-1 inhibitors in lung adenocarcinoma.

Authors: Lee, Seul-Ki, Hwang, Yoonjung, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo, Koh, Young Wha

Year: 2023

Venue: American journal of cancer research

Paper Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.

Das, Rituparna, Verma, Rakesh, Sznol, Mario, Boddupalli, Chandra Sekhar, Gettinger, Scott N, Kluger, Harriet, Callahan, Margaret, Wolchok, Jedd D, Halaban, Ruth, Dhodapkar, Madhav V, Dhodapkar, Kavita M · 2015 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.

Authors: Das, Rituparna, Verma, Rakesh, Sznol, Mario, Boddupalli, Chandra Sekhar, Gettinger, Scott N, Kluger, Harriet, Callahan, Margaret, Wolchok, Jedd D, Halaban, Ruth, Dhodapkar, Madhav V, Dhodapkar, Kavita M

Year: 2015

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.1401686

Paper Control of Memory Phenotype T Lymphocyte Homeostasis: Role of Costimulation.

Panda, Abir K, Kim, Yong-Hee, Shevach, Ethan M · 2022 · Journal of immunology (Baltimore, Md. : 1950) · DOI

Full title: Control of Memory Phenotype T Lymphocyte Homeostasis: Role of Costimulation.

Authors: Panda, Abir K, Kim, Yong-Hee, Shevach, Ethan M

Year: 2022

Venue: Journal of immunology (Baltimore, Md. : 1950)

DOI: https://doi.org/10.4049/jimmunol.2100653

Paper Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints.

Chang, Lee-Shing, Barroso-Sousa, Romualdo, Tolaney, Sara M, Hodi, F Stephen, Kaiser, Ursula B, Min, Le · 2019 · Endocrine reviews · DOI

Full title: Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints.

Authors: Chang, Lee-Shing, Barroso-Sousa, Romualdo, Tolaney, Sara M, Hodi, F Stephen, Kaiser, Ursula B, Min, Le

Year: 2019

Venue: Endocrine reviews

DOI: https://doi.org/10.1210/er.2018-00006

Paper Impact of immune-related adverse event severity on overall survival in patients with advanced NSCLC receiving immune checkpoint inhibitors therapy, with a focus on combination regimens.

Sugai, Mayu, Amino, Yoshiaki, Fujishima, Shunsuke, Nibuya, Kyujiro, Iso, Hirokazu, Ito, Masahiro, Tsugitomi, Ryosuke, Ariyasu, Ryo, Uchibori, Ken, Yanagitani, Noriko, Nishio, Makoto · 2025 · Lung cancer (Amsterdam, Netherlands) · DOI

Full title: Impact of immune-related adverse event severity on overall survival in patients with advanced NSCLC receiving immune checkpoint inhibitors therapy, with a focus on combination regimens.

Authors: Sugai, Mayu, Amino, Yoshiaki, Fujishima, Shunsuke, Nibuya, Kyujiro, Iso, Hirokazu, Ito, Masahiro, Tsugitomi, Ryosuke, Ariyasu, Ryo, Uchibori, Ken, Yanagitani, Noriko, Nishio, Makoto

Year: 2025

Venue: Lung cancer (Amsterdam, Netherlands)

DOI: https://doi.org/10.1016/j.lungcan.2025.108555

Paper CTLA-4 Limits Anti-CD20-Mediated Tumor Regression.

Ren, Zhenhua, Guo, Jingya, Liao, Jing, Luan, Yan, Liu, Zhida, Sun, Zhichen, Liu, Xiaojuan, Liang, Yong, Peng, Hua, Fu, Yang-Xin · 2017 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: CTLA-4 Limits Anti-CD20-Mediated Tumor Regression.

Authors: Ren, Zhenhua, Guo, Jingya, Liao, Jing, Luan, Yan, Liu, Zhida, Sun, Zhichen, Liu, Xiaojuan, Liang, Yong, Peng, Hua, Fu, Yang-Xin

Year: 2017

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-16-0040

Paper Neoadjuvant Therapies for Bladder Cancer in Cisplatin-ineligible Patients: What Options Do We Have?

Basu, Arnab, Sadeghi, Sarmad · 2020 · European urology focus · DOI

Full title: Neoadjuvant Therapies for Bladder Cancer in Cisplatin-ineligible Patients: What Options Do We Have?

Authors: Basu, Arnab, Sadeghi, Sarmad

Year: 2020

Venue: European urology focus

DOI: https://doi.org/10.1016/j.euf.2019.10.017

Paper Pancreatic cancer is feeling the heat

Maru, Saumya, Jaffee, Elizabeth M. · 2024 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Pancreatic cancer is feeling the heat

Authors: Maru, Saumya, Jaffee, Elizabeth M.

Year: 2024

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2024-010124

Paper Determinants of overall survival in patients with metastatic uveal melanoma.

Demkowicz, Patrick, Pointdujour-Lim, Renelle, Miguez, Sofia, Lee, Yesung, Jones, Bailey S C L, Barker, Christopher A, Bosenberg, Marcus, Abramson, David H, Shoushtari, Alexander N, Kluger, Harriet, Francis, Jasmine H, Sznol, Mario, Bakhoum, Mathieu F · 2023 · Cancer · DOI

Full title: Determinants of overall survival in patients with metastatic uveal melanoma.

Authors: Demkowicz, Patrick, Pointdujour-Lim, Renelle, Miguez, Sofia, Lee, Yesung, Jones, Bailey S C L, Barker, Christopher A, Bosenberg, Marcus, Abramson, David H, Shoushtari, Alexander N, Kluger, Harriet, Francis, Jasmine H, Sznol, Mario, Bakhoum, Mathieu F

Year: 2023

Venue: Cancer

DOI: https://doi.org/10.1002/cncr.34927

Paper Hypophysitis related to immune checkpoint inhibitors: An intriguing adverse event with many faces.

Deligiorgi, Maria V, Liapi, Charis, Trafalis, Dimitrios T · 2021 · Expert opinion on biological therapy · DOI

Full title: Hypophysitis related to immune checkpoint inhibitors: An intriguing adverse event with many faces.

Authors: Deligiorgi, Maria V, Liapi, Charis, Trafalis, Dimitrios T

Year: 2021

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2021.1869211

Paper Research advances in radiotherapy combined with immune checkpoint blockade

Song, Xing · 2017 · Zhonghua fangshe zhongliuxue zazhi · DOI

Full title: Research advances in radiotherapy combined with immune checkpoint blockade

Authors: Song, Xing

Year: 2017

Venue: Zhonghua fangshe zhongliuxue zazhi

DOI: https://doi.org/10.3760/cma.j.issn.1004-4221.2017.03.022

Paper Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report.

Cho, Hye Jung, Kim, Woo Ram, Kim, Joo-Hang, Kim, Duk Hwan, Kim, Dae Jung, Kang, Haeyoun · 2021 · Annals of coloproctology · DOI

Full title: Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report.

Authors: Cho, Hye Jung, Kim, Woo Ram, Kim, Joo-Hang, Kim, Duk Hwan, Kim, Dae Jung, Kang, Haeyoun

Year: 2021

Venue: Annals of coloproctology

DOI: https://doi.org/10.3393/ac.2020.00213.0030

Paper Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients.

Jensen, Christina, Madsen, Daniel Hargbøl, Hansen, Morten, Schmidt, Henrik, Svane, Inge Marie, Karsdal, Morten Asser, Willumsen, Nicholas · 2018 · Journal for immunotherapy of cancer · DOI

Full title: Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients.

Authors: Jensen, Christina, Madsen, Daniel Hargbøl, Hansen, Morten, Schmidt, Henrik, Svane, Inge Marie, Karsdal, Morten Asser, Willumsen, Nicholas

Year: 2018

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-018-0474-z

Paper Impact of Bone Metastasis in Stage IV Non–Small Cell Lung Cancer Treated With Durvalumab and Tremelimumab With or Without Chemotherapy: A Retrospective Analysis of the CCTG BR.34 Trial

Annageldiyev, Charyguly, Gaudreau, Pierre-Olivier, Leitzel, Kim, Ali, Suhail M., Ding, Keyue, Leighl, Natasha B., Vera-Badillo, Francisco, Bradbury, Penelope Ann, Goss, Glenwood, Shepherd, Lois E., Costa, Luís, Suva, Larry J., Hughes, Brett, Stockler, Martin R., Drabick, Joseph J., Patrick, C., Joshi, Monika, Moku, Prashanth, Polimera, Hyma, Louis, Peter C., Ramachandrula, Priya, Lipton, Allan · 2024 · JCO oncology advances. · DOI

Full title: Impact of Bone Metastasis in Stage IV Non–Small Cell Lung Cancer Treated With Durvalumab and Tremelimumab With or Without Chemotherapy: A Retrospective Analysis of the CCTG BR.34 Trial

Authors: Annageldiyev, Charyguly, Gaudreau, Pierre-Olivier, Leitzel, Kim, Ali, Suhail M., Ding, Keyue, Leighl, Natasha B., Vera-Badillo, Francisco, Bradbury, Penelope Ann, Goss, Glenwood, Shepherd, Lois E., Costa, Luís, Suva, Larry J., Hughes, Brett, Stockler, Martin R., Drabick, Joseph J., Patrick, C., Joshi, Monika, Moku, Prashanth, Polimera, Hyma, Louis, Peter C., Ramachandrula, Priya, Lipton, Allan

Year: 2024

Venue: JCO oncology advances.

DOI: https://doi.org/10.1200/oa.24.00017

Paper Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro

M. Rossi, Andrea Vecchi, Camilla Tiezzi, Valeria Barili, P. Fisicaro, A. Penna, Ilaria Montali, S. Daffis, S. Fletcher, A. Gaggar, Jonathan Medley, M. Graupe, L. Lad, A. Loglio, R. Soffredini, M. Borghi, T. Pollicino, C. Musolino, A. Alfieri, F. Brillo, D. Laccabue, M. Massari, Chiara Boarini, G. Abbati, G. Pedrazzi, G. Missale, P. Lampertico, C. Ferrari, C. Boni · 2023 · Gut · DOI

Full title: Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro

Authors: M. Rossi, Andrea Vecchi, Camilla Tiezzi, Valeria Barili, P. Fisicaro, A. Penna, Ilaria Montali, S. Daffis, S. Fletcher, A. Gaggar, Jonathan Medley, M. Graupe, L. Lad, A. Loglio, R. Soffredini, M. Borghi, T. Pollicino, C. Musolino, A. Alfieri, F. Brillo, D. Laccabue, M. Massari, Chiara Boarini, G. Abbati, G. Pedrazzi, G. Missale, P. Lampertico, C. Ferrari, C. Boni

Year: 2023

Venue: Gut

DOI: https://doi.org/10.1136/gutjnl-2022-327202

Paper Systematic review: colitis associated with anti-CTLA-4 therapy.

Gupta, A, De Felice, K M, Loftus, E V, Khanna, S · 2015 · Alimentary pharmacology & therapeutics · DOI

Full title: Systematic review: colitis associated with anti-CTLA-4 therapy.

Authors: Gupta, A, De Felice, K M, Loftus, E V, Khanna, S

Year: 2015

Venue: Alimentary pharmacology & therapeutics

DOI: https://doi.org/10.1111/apt.13281

Paper CD80 and CD86: expression and prognostic value in newly diagnosed glioblastoma

Mohammed Ahmed, I. Hernández-Verdin, M. Verreault, F. Bielle, J. Lerond, A. Alentorn, M. Sanson, A. Idbaih · 2021 · DOI

Full title: CD80 and CD86: expression and prognostic value in newly diagnosed glioblastoma

Authors: Mohammed Ahmed, I. Hernández-Verdin, M. Verreault, F. Bielle, J. Lerond, A. Alentorn, M. Sanson, A. Idbaih

Year: 2021

DOI: https://doi.org/10.21203/rs.3.rs-437279/v1

Paper Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.

Hu-Lieskovan, Siwen, Mok, Stephen, Homet Moreno, Blanca, Tsoi, Jennifer, Robert, Lidia, Goedert, Lucas, Pinheiro, Elaine M, Koya, Richard C, Graeber, Thomas G, Comin-Anduix, Begoña, Ribas, Antoni · 2015 · Science translational medicine · DOI

Full title: Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.

Authors: Hu-Lieskovan, Siwen, Mok, Stephen, Homet Moreno, Blanca, Tsoi, Jennifer, Robert, Lidia, Goedert, Lucas, Pinheiro, Elaine M, Koya, Richard C, Graeber, Thomas G, Comin-Anduix, Begoña, Ribas, Antoni

Year: 2015

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.aaa4691

Paper Immunotherapy use outside clinical trial populations: never say never?

K. Rzeniewicz, J. Larkin, A. Menzies, S. Turajlic · 2021 · Annals of Oncology · DOI

Full title: Immunotherapy use outside clinical trial populations: never say never?

Authors: K. Rzeniewicz, J. Larkin, A. Menzies, S. Turajlic

Year: 2021

Venue: Annals of Oncology

DOI: https://doi.org/10.1016/j.annonc.2021.03.199

Paper Improved tumor accumulation and therapeutic efficacy of CTLA-4-blocking antibody using liposome-encapsulated antibody: In vitro and in vivo studies.

Nikpoor, Amin Reza, Tavakkol-Afshari, Jalil, Sadri, Kayvan, Jalali, Seyed Amir, Jaafari, Mahmoud Reza · 2017 · Nanomedicine : nanotechnology, biology, and medicine · DOI

Full title: Improved tumor accumulation and therapeutic efficacy of CTLA-4-blocking antibody using liposome-encapsulated antibody: In vitro and in vivo studies.

Authors: Nikpoor, Amin Reza, Tavakkol-Afshari, Jalil, Sadri, Kayvan, Jalali, Seyed Amir, Jaafari, Mahmoud Reza

Year: 2017

Venue: Nanomedicine : nanotechnology, biology, and medicine

DOI: https://doi.org/10.1016/j.nano.2017.08.010

Paper 66 Early Experiences of the Use of Combination Immunotherapy for the Treatment of Malignant Mesothelioma from 2022–2023 – Real-World Evidence of 1-Year Data from a Single UK Tertiary Cancer Centre

J. Liu, Stephanie R. Harrison, Dan Lee · 2024 · Lung Cancer · DOI

Full title: 66 Early Experiences of the Use of Combination Immunotherapy for the Treatment of Malignant Mesothelioma from 2022–2023 – Real-World Evidence of 1-Year Data from a Single UK Tertiary Cancer Centre

Authors: J. Liu, Stephanie R. Harrison, Dan Lee

Year: 2024

Venue: Lung Cancer

DOI: https://doi.org/10.1016/j.lungcan.2024.107627

Paper Combination immunotherapy for hepatocellular carcinoma.

Rimassa, Lorenza, Finn, Richard S, Sangro, Bruno · 2023 · Journal of hepatology · DOI

Full title: Combination immunotherapy for hepatocellular carcinoma.

Authors: Rimassa, Lorenza, Finn, Richard S, Sangro, Bruno

Year: 2023

Venue: Journal of hepatology

DOI: https://doi.org/10.1016/j.jhep.2023.03.003

Paper Abstract 3678: Muc4 nanovaccine and checkpoint blockade based combination immunotherapy for pancreatic cancer

Banerjee, Kasturi, Gautam, Shailendra K., Nasser, Waseem Mohd., Kshirsagar, Prakash, Ross, Kathleen A., Spagnol, Gaëlle, Aithal, Abhijit, Sorgen, Paul L., Batra, Surinder K., Kumar, Sushil, Narasimhan, Balaji, Jain, Maneesh · 2017 · Cancer Research · DOI

Full title: Abstract 3678: Muc4 nanovaccine and checkpoint blockade based combination immunotherapy for pancreatic cancer

Authors: Banerjee, Kasturi, Gautam, Shailendra K., Nasser, Waseem Mohd., Kshirsagar, Prakash, Ross, Kathleen A., Spagnol, Gaëlle, Aithal, Abhijit, Sorgen, Paul L., Batra, Surinder K., Kumar, Sushil, Narasimhan, Balaji, Jain, Maneesh

Year: 2017

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2017-3678

Paper Case series of cancer patients who developed cholecystitis related to immune checkpoint inhibitor treatment.

Abu-Sbeih, Hamzah, Tran, Cynthia Nguyen, Ge, Phillip S, Bhutani, Manoop S, Alasadi, Mazen, Naing, Aung, Jazaeri, Amir A, Wang, Yinghong · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Case series of cancer patients who developed cholecystitis related to immune checkpoint inhibitor treatment.

Authors: Abu-Sbeih, Hamzah, Tran, Cynthia Nguyen, Ge, Phillip S, Bhutani, Manoop S, Alasadi, Mazen, Naing, Aung, Jazaeri, Amir A, Wang, Yinghong

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0604-2

Paper Multispectral imaging and objective assessment of immune-tumor interactions in non-small cell lung cancer

C. Ballesteros-Merino, M. Neuberger, Zipei Feng, R. Huber, J. Stump, Amanda Tufman, R. Hatz, Michaela Linder, R. Sanborn, S. Hussain, J. Handy, W. Urba, B. Fox, C. Bifulco, S. Reu, H. Winter · 2015 · Journal of Immunotherapy for Cancer · DOI

Full title: Multispectral imaging and objective assessment of immune-tumor interactions in non-small cell lung cancer

Authors: C. Ballesteros-Merino, M. Neuberger, Zipei Feng, R. Huber, J. Stump, Amanda Tufman, R. Hatz, Michaela Linder, R. Sanborn, S. Hussain, J. Handy, W. Urba, B. Fox, C. Bifulco, S. Reu, H. Winter

Year: 2015

Venue: Journal of Immunotherapy for Cancer

DOI: https://doi.org/10.1186/2051-1426-3-s2-p394

Paper Combination therapy of cytotoxic t-lymphocyte-associated antigen 4 (ctla-4) and programmed death 1 (pd 1) blocker, check point inhibitors for treatment of patients with advanced and recurrent epithelial ovarian cancer.

Farghaly, S A · 2017 · European journal of gynaecological oncology

Full title: Combination therapy of cytotoxic t-lymphocyte-associated antigen 4 (ctla-4) and programmed death 1 (pd 1) blocker, check point inhibitors for treatment of patients with advanced and recurrent epithelial ovarian cancer.

Authors: Farghaly, S A

Year: 2017

Venue: European journal of gynaecological oncology

Paper Rationale for combined blockade of PD-1 and CTLA-4 in advanced head and neck squamous cell cancer—review of current data.

Swanson, Mark S, Sinha, Uttam K · 2015 · Oral oncology · DOI

Full title: Rationale for combined blockade of PD-1 and CTLA-4 in advanced head and neck squamous cell cancer—review of current data.

Authors: Swanson, Mark S, Sinha, Uttam K

Year: 2015

Venue: Oral oncology

DOI: https://doi.org/10.1016/j.oraloncology.2014.10.010

Paper A systematic review of phase II trials exploring anti-PD-1/PD-L1 combinations in patients with solid tumors.

Martorana, F, Colombo, I, Treglia, G, Gillessen, S, Stathis, A · 2021 · Cancer treatment reviews · DOI

Full title: A systematic review of phase II trials exploring anti-PD-1/PD-L1 combinations in patients with solid tumors.

Authors: Martorana, F, Colombo, I, Treglia, G, Gillessen, S, Stathis, A

Year: 2021

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2021.102300

Paper Prussian blue nanoparticle-based photothermal therapy combined with checkpoint inhibition for photothermal immunotherapy of neuroblastoma.

Cano-Mejia, Juliana, Burga, Rachel A, Sweeney, Elizabeth E, Fisher, John P, Bollard, Catherine M, Sandler, Anthony D, Cruz, Conrad Russell Y, Fernandes, Rohan · 2017 · Nanomedicine : nanotechnology, biology, and medicine · DOI

Full title: Prussian blue nanoparticle-based photothermal therapy combined with checkpoint inhibition for photothermal immunotherapy of neuroblastoma.

Authors: Cano-Mejia, Juliana, Burga, Rachel A, Sweeney, Elizabeth E, Fisher, John P, Bollard, Catherine M, Sandler, Anthony D, Cruz, Conrad Russell Y, Fernandes, Rohan

Year: 2017

Venue: Nanomedicine : nanotechnology, biology, and medicine

DOI: https://doi.org/10.1016/j.nano.2016.10.015

Paper Personalized Immuno-Oncology

Jain, Kewal K. · 2020 · Medical Principles and Practice · DOI

Full title: Personalized Immuno-Oncology

Authors: Jain, Kewal K.

Year: 2020

Venue: Medical Principles and Practice

DOI: https://doi.org/10.1159/000511107

Paper [Development of immune checkpoint inhibitor in colorectal cancer].

Kitano, Shigehisa · 2016 · Nihon rinsho. Japanese journal of clinical medicine

Full title: [Development of immune checkpoint inhibitor in colorectal cancer].

Authors: Kitano, Shigehisa

Year: 2016

Venue: Nihon rinsho. Japanese journal of clinical medicine

Paper DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Year: 2024

DOI: https://doi.org/10.7554/elife.87292.2

Paper [Current advances in immunotherapy in ovarian cancer].

Le Saux, Olivia, Dubois, Bertrand, Stern, Marc-Henri, Terme, Magali, Tartour, Eric, Classe, Jean-Marc, Chopin, Nicolas, Trédan, Olivier, Caux, Christophe, Ray-Coquard, Isabelle · 2020 · Bulletin du cancer · DOI

Full title: [Current advances in immunotherapy in ovarian cancer].

Authors: Le Saux, Olivia, Dubois, Bertrand, Stern, Marc-Henri, Terme, Magali, Tartour, Eric, Classe, Jean-Marc, Chopin, Nicolas, Trédan, Olivier, Caux, Christophe, Ray-Coquard, Isabelle

Year: 2020

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2019.11.015

Paper Immune-related adverse events in various organs caused by immune checkpoint inhibitors.

Okiyama, Naoko, Tanaka, Ryota · 2022 · Allergology international : official journal of the Japanese Society of Allergology · DOI

Full title: Immune-related adverse events in various organs caused by immune checkpoint inhibitors.

Authors: Okiyama, Naoko, Tanaka, Ryota

Year: 2022

Venue: Allergology international : official journal of the Japanese Society of Allergology

DOI: https://doi.org/10.1016/j.alit.2022.01.001

Paper Combination therapies for the treatment of advanced melanoma: a review of current evidence.

Voskoboynik, Mark, Arkenau, Hendrik-Tobias · 2014 · Biochemistry research international · DOI

Full title: Combination therapies for the treatment of advanced melanoma: a review of current evidence.

Authors: Voskoboynik, Mark, Arkenau, Hendrik-Tobias

Year: 2014

Venue: Biochemistry research international

DOI: https://doi.org/10.1155/2014/307059

Paper Toxicity and response to ipilimumab and nivolumab in older patients with metastatic melanoma: A multicentre retrospective analysis.

Pathmanathan, Shivanshan, Babu, Hari, Dzienis, Marcin, Azer, Mary, Eastgate, Melissa · 2022 · Pigment cell & melanoma research · DOI

Full title: Toxicity and response to ipilimumab and nivolumab in older patients with metastatic melanoma: A multicentre retrospective analysis.

Authors: Pathmanathan, Shivanshan, Babu, Hari, Dzienis, Marcin, Azer, Mary, Eastgate, Melissa

Year: 2022

Venue: Pigment cell & melanoma research

DOI: https://doi.org/10.1111/pcmr.13063

Paper Early peripheral T-cell responses predict oncological outcome to checkpoint immune blockade in metastatic melanoma

B. Fairfax, Chelsea A. Taylor, R. A. Watson, I. Nassiri, Hai Fang, E. Mahé, R. Cooper, S. Danielli, V. Woodcock, Z. Traill, J. Knight, M. Payne, M. Middleton · 2019 · Annals of Oncology · DOI

Full title: Early peripheral T-cell responses predict oncological outcome to checkpoint immune blockade in metastatic melanoma

Authors: B. Fairfax, Chelsea A. Taylor, R. A. Watson, I. Nassiri, Hai Fang, E. Mahé, R. Cooper, S. Danielli, V. Woodcock, Z. Traill, J. Knight, M. Payne, M. Middleton

Year: 2019

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdz253.020

Paper [PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer].

Monneur, Audrey, Gonçalves, Anthony, Bertucci, François · 2018 · Bulletin du cancer · DOI

Full title: [PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer].

Authors: Monneur, Audrey, Gonçalves, Anthony, Bertucci, François

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2017.11.012

Paper Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis.

Shrimali, Rajeev K, Ahmad, Shamim, Verma, Vivek, Zeng, Peng, Ananth, Sudha, Gaur, Pankaj, Gittelman, Rachel M, Yusko, Erik, Sanders, Catherine, Robins, Harlan, Hammond, Scott A, Janik, John E, Mkrtichyan, Mikayel, Gupta, Seema, Khleif, Samir N · 2017 · Cancer immunology research · DOI

Full title: Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis.

Authors: Shrimali, Rajeev K, Ahmad, Shamim, Verma, Vivek, Zeng, Peng, Ananth, Sudha, Gaur, Pankaj, Gittelman, Rachel M, Yusko, Erik, Sanders, Catherine, Robins, Harlan, Hammond, Scott A, Janik, John E, Mkrtichyan, Mikayel, Gupta, Seema, Khleif, Samir N

Year: 2017

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-17-0292

Paper Immunotherapy in Lung Cancer.

Castellanos, Emily H, Horn, Leora · 2016 · Cancer treatment and research · DOI

Full title: Immunotherapy in Lung Cancer.

Authors: Castellanos, Emily H, Horn, Leora

Year: 2016

Venue: Cancer treatment and research

DOI: https://doi.org/10.1007/978-3-319-40389-2_10

Paper Immune signatures predicting responses to immunomodulatory antibody therapy.

Pawelec, Graham · 2018 · Current opinion in immunology · DOI

Full title: Immune signatures predicting responses to immunomodulatory antibody therapy.

Authors: Pawelec, Graham

Year: 2018

Venue: Current opinion in immunology

DOI: https://doi.org/10.1016/j.coi.2018.03.003

Paper Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application.

Tray, Nancy, Weber, Jeffrey S, Adams, Sylvia · 2018 · Cancer immunology research · DOI

Full title: Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application.

Authors: Tray, Nancy, Weber, Jeffrey S, Adams, Sylvia

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0214

Paper Dual immune checkpoint blockade for non-small cell lung cancer patients with PD-L1 high expression: calling an end?

Peng, Ling, Stebbing, Justin, Liang, Fei, Xia, Yang · 2021 · Translational lung cancer research · DOI

Full title: Dual immune checkpoint blockade for non-small cell lung cancer patients with PD-L1 high expression: calling an end?

Authors: Peng, Ling, Stebbing, Justin, Liang, Fei, Xia, Yang

Year: 2021

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-21-650

Paper Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non-Small Cell Lung Cancer.

Li, Jia-Xin, Huang, Ju-Min, Jiang, Ze-Bo, Li, Run-Ze, Sun, Ao, Lai-Han Leung, Elaine, Yan, Pei-Yu · 2019 · Integrative cancer therapies · DOI

Full title: Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non-Small Cell Lung Cancer.

Authors: Li, Jia-Xin, Huang, Ju-Min, Jiang, Ze-Bo, Li, Run-Ze, Sun, Ao, Lai-Han Leung, Elaine, Yan, Pei-Yu

Year: 2019

Venue: Integrative cancer therapies

DOI: https://doi.org/10.1177/1534735419890020

Paper Prodrugs of paclitaxel improve in situ photo-vaccination.

Giram, Prabhanjan, Bist, Ganesh, Woo, Sukyung, Wohlfert, Elizabeth, Pili, Roberto, You, Youngjae · 2025 · Photochemistry and photobiology · DOI

Full title: Prodrugs of paclitaxel improve in situ photo-vaccination.

Authors: Giram, Prabhanjan, Bist, Ganesh, Woo, Sukyung, Wohlfert, Elizabeth, Pili, Roberto, You, Youngjae

Year: 2025

Venue: Photochemistry and photobiology

DOI: https://doi.org/10.1111/php.14025

Paper Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration adverse events reporting system.

Zhai, Yinghong, Ye, Xiaofei, Hu, Fangyuan, Xu, Jinfang, Guo, Xiaojing, Zhuang, Yonglong, He, Jia · 2019 · Journal for immunotherapy of cancer · DOI

Full title: Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration adverse events reporting system.

Authors: Zhai, Yinghong, Ye, Xiaofei, Hu, Fangyuan, Xu, Jinfang, Guo, Xiaojing, Zhuang, Yonglong, He, Jia

Year: 2019

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-019-0754-2

Paper ROSE12, a novel anti-CTLA-4 FcγRs binding-enhanced antibody activated by extracellular adenosine triphosphate, shows tumor-selective regulatory T-cell depletion and antitumor efficacy without systemic immune activation.

Hayashi, Hiroki, Tatsumi, Kanako, Katada, Hitoshi, Matsuda, Yutaka, Tsunenari, Toshiaki, Honda, Masaki, Nemoto, Takayuki, Shimizu, Shun, Miura-Okuda, Momoko, Ikuta, Yuri, Ito, Ami, Ogami, Chika, Kato, Chie, Kamimura, Masaki, Kibayashi, Tatsuya, Kubo, Chiyomi, Komatsu, Shunichiro, Komori, Yasunori, Shinozuka, Junko, Susumu, Hiroaki, Tanno, Honoka, Tomii, Yasushi, Nakagawa, Kenji, Nagano, Hiroaki, Nanami, Masahiko, Nishito, Yukari, Fujisawa, Nozomi, Matsushita, Tomochika, Michisaka, Saki, Yamazaki, Masaki, Yoshimoto, Moe, Wakatsuki, Hiroaki, Wakabayashi, Tetsuya, Wada, Naoko A, Ueda, Otoya, Konishi, Hiroko, Kashima, Kenji, Tanaka, Hiroshi, Endo, Mika, Kitazawa, Takehisa, Sakaguchi, Shimon, Kamata-Sakurai, Mika, Igawa, Tomoyuki · 2026 · Journal for immunotherapy of cancer · DOI

Full title: ROSE12, a novel anti-CTLA-4 FcγRs binding-enhanced antibody activated by extracellular adenosine triphosphate, shows tumor-selective regulatory T-cell depletion and antitumor efficacy without systemic immune activation.

Authors: Hayashi, Hiroki, Tatsumi, Kanako, Katada, Hitoshi, Matsuda, Yutaka, Tsunenari, Toshiaki, Honda, Masaki, Nemoto, Takayuki, Shimizu, Shun, Miura-Okuda, Momoko, Ikuta, Yuri, Ito, Ami, Ogami, Chika, Kato, Chie, Kamimura, Masaki, Kibayashi, Tatsuya, Kubo, Chiyomi, Komatsu, Shunichiro, Komori, Yasunori, Shinozuka, Junko, Susumu, Hiroaki, Tanno, Honoka, Tomii, Yasushi, Nakagawa, Kenji, Nagano, Hiroaki, Nanami, Masahiko, Nishito, Yukari, Fujisawa, Nozomi, Matsushita, Tomochika, Michisaka, Saki, Yamazaki, Masaki, Yoshimoto, Moe, Wakatsuki, Hiroaki, Wakabayashi, Tetsuya, Wada, Naoko A, Ueda, Otoya, Konishi, Hiroko, Kashima, Kenji, Tanaka, Hiroshi, Endo, Mika, Kitazawa, Takehisa, Sakaguchi, Shimon, Kamata-Sakurai, Mika, Igawa, Tomoyuki

Year: 2026

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2025-013397

Paper Phenotypic characterization of tumor CTLA-4 expression in melanoma tissues and its possible role in clinical response to Ipilimumab.

M. Pistillo, R. Carosio, F. Grillo, V. Fontana, L. Mastracci, A. Morabito, B. Banelli, E. Tanda, F. Cecchi, B. Dozin, M. Gualco, S. Salvi, F. Spagnolo, A. Poggi, P. Queirolo · 2020 · Clinical Immunology · DOI

Full title: Phenotypic characterization of tumor CTLA-4 expression in melanoma tissues and its possible role in clinical response to Ipilimumab.

Authors: M. Pistillo, R. Carosio, F. Grillo, V. Fontana, L. Mastracci, A. Morabito, B. Banelli, E. Tanda, F. Cecchi, B. Dozin, M. Gualco, S. Salvi, F. Spagnolo, A. Poggi, P. Queirolo

Year: 2020

Venue: Clinical Immunology

DOI: https://doi.org/10.1016/j.clim.2020.108428

Paper Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity.

Alvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, Maria Carmen, Perez-Ruiz, Elisabeth, Melero, Ignacio, Berraondo, Pedro · 2019 · Cell stress · DOI

Full title: Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity.

Authors: Alvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, Maria Carmen, Perez-Ruiz, Elisabeth, Melero, Ignacio, Berraondo, Pedro

Year: 2019

Venue: Cell stress

DOI: https://doi.org/10.15698/cst2019.07.193

Paper European Medicines Agency extension of indication to include the combination immunotherapy cancer drug treatment with nivolumab (Opdivo) and ipilimumab (Yervoy) for adults with intermediate/poor-risk advanced renal cell carcinoma

Ali, Sahra, Camarero, Jorge, Hennik, Paula B. van, Bolstad, B., Grønvold, Maja Sommerfelt, Syvertsen, Christian, Strøm, Bjørn Oddvar, Ökvist, Mats, Josephson, Filip, Keller‐Stanislawski, Brigitte, Zafiropoulos, Nikolaos, Péan, Elias, Bergh, Jonas, Dias, Silvy da Rocha, Pignatti, Francesco · 2020 · ESMO Open · DOI

Full title: European Medicines Agency extension of indication to include the combination immunotherapy cancer drug treatment with nivolumab (Opdivo) and ipilimumab (Yervoy) for adults with intermediate/poor-risk advanced renal cell carcinoma

Authors: Ali, Sahra, Camarero, Jorge, Hennik, Paula B. van, Bolstad, B., Grønvold, Maja Sommerfelt, Syvertsen, Christian, Strøm, Bjørn Oddvar, Ökvist, Mats, Josephson, Filip, Keller‐Stanislawski, Brigitte, Zafiropoulos, Nikolaos, Péan, Elias, Bergh, Jonas, Dias, Silvy da Rocha, Pignatti, Francesco

Year: 2020

Venue: ESMO Open

DOI: https://doi.org/10.1136/esmoopen-2020-000798

Paper The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth.

McCaw, Tyler R, Li, Mei, Starenki, Dmytro, Cooper, Sara J, Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C, Buchsbaum, Donald J, Forero, Andres, Randall, Troy D · 2019 · Cancer immunology, immunotherapy : CII · DOI

Full title: The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth.

Authors: McCaw, Tyler R, Li, Mei, Starenki, Dmytro, Cooper, Sara J, Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C, Buchsbaum, Donald J, Forero, Andres, Randall, Troy D

Year: 2019

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-018-2262-5

Paper Rational design of anti-GITR-based combination immunotherapy

Zappasodi, R, Sirard, C, Li, Y, Budhu, S, Abu-Akeel, M, Liu, C, Yang, Xiu‐Li, Zhong, Huimi, Newman, W, Qi, Jinglin, Wong, P, Schaer, D, Koon, H, Velcheti, V, Hellman, MD, Postow, MA, Callahan, MK, Wolchok, J. D., Merghoub, T · 2019 · immuneACCESS · DOI

Full title: Rational design of anti-GITR-based combination immunotherapy

Authors: Zappasodi, R, Sirard, C, Li, Y, Budhu, S, Abu-Akeel, M, Liu, C, Yang, Xiu‐Li, Zhong, Huimi, Newman, W, Qi, Jinglin, Wong, P, Schaer, D, Koon, H, Velcheti, V, Hellman, MD, Postow, MA, Callahan, MK, Wolchok, J. D., Merghoub, T

Year: 2019

Venue: immuneACCESS

DOI: https://doi.org/10.21417/rz2019nm

Paper Abstract 2822: Low intestinal microbial diversity is associated with severe immune-related adverse events and lack of response to neoadjuvant combination antiPD1, anti-CTLA4 immunotherapy

M. Batten, E. Shanahan, I. Silva, C. Adhikari, J. Conway, Annie Tasker, A. Menzies, J. Wilmott, R. Saw, A. Spillane, K. Shannon, C. Blank, A. Holmes, R. Scolyer, G. Long · 2019 · Tumor Biology · DOI

Full title: Abstract 2822: Low intestinal microbial diversity is associated with severe immune-related adverse events and lack of response to neoadjuvant combination antiPD1, anti-CTLA4 immunotherapy

Authors: M. Batten, E. Shanahan, I. Silva, C. Adhikari, J. Conway, Annie Tasker, A. Menzies, J. Wilmott, R. Saw, A. Spillane, K. Shannon, C. Blank, A. Holmes, R. Scolyer, G. Long

Year: 2019

Venue: Tumor Biology

DOI: https://doi.org/10.1158/1538-7445.am2019-2822

Paper Unresectable cardiac metastasis from melanoma responds well to combination immunotherapy-a case report.

Oh, Ek Leone, Dias, Peter, Al-Ogaili, Zeyad, Otto, Jacobus, Warburton, Lydia · 2024 · European heart journal. Case reports · DOI

Full title: Unresectable cardiac metastasis from melanoma responds well to combination immunotherapy-a case report.

Authors: Oh, Ek Leone, Dias, Peter, Al-Ogaili, Zeyad, Otto, Jacobus, Warburton, Lydia

Year: 2024

Venue: European heart journal. Case reports

DOI: https://doi.org/10.1093/ehjcr/ytae262

Paper Treg-mediated acquired resistance to immune checkpoint inhibitors.

Saleh, Reem, Elkord, Eyad · 2019 · Cancer letters · DOI

Full title: Treg-mediated acquired resistance to immune checkpoint inhibitors.

Authors: Saleh, Reem, Elkord, Eyad

Year: 2019

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2019.05.003

Paper Type 1 diabetes induced by immune checkpoint inhibitors.

Zhang, Rui, Cai, Xiao-Ling, Liu, Liu, Han, Xue-Yao, Ji, Li-Nong · 2020 · Chinese medical journal · DOI

Full title: Type 1 diabetes induced by immune checkpoint inhibitors.

Authors: Zhang, Rui, Cai, Xiao-Ling, Liu, Liu, Han, Xue-Yao, Ji, Li-Nong

Year: 2020

Venue: Chinese medical journal

DOI: https://doi.org/10.1097/CM9.0000000000000972

Paper Hypothyroidism in Cancer Patients on Immune Checkpoint Inhibitors with anti-PD1 Agents: Insights on Underlying Mechanisms.

Alhusseini, M, Samantray, J · 2017 · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · DOI

Full title: Hypothyroidism in Cancer Patients on Immune Checkpoint Inhibitors with anti-PD1 Agents: Insights on Underlying Mechanisms.

Authors: Alhusseini, M, Samantray, J

Year: 2017

Venue: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

DOI: https://doi.org/10.1055/s-0042-119528

Paper Biliary disorders associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database.

Wei, Shiju, Zhang, Zhenyu, Song, Xuhua, Chen, Rui, Chen, Siyu, Lu, Baoping · 2026 · Journal of chemotherapy (Florence, Italy) · DOI

Full title: Biliary disorders associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database.

Authors: Wei, Shiju, Zhang, Zhenyu, Song, Xuhua, Chen, Rui, Chen, Siyu, Lu, Baoping

Year: 2026

Venue: Journal of chemotherapy (Florence, Italy)

DOI: https://doi.org/10.1080/1120009X.2025.2612386

Paper Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentiation Status in Glioblastoma.

Park, Junsik, Kwon, Minsuk, Kim, Kyung Hwan, Kim, Tae-Shin, Hong, Seon-Hui, Kim, Chang Gon, Kang, Seok-Gu, Moon, Ju Hyung, Kim, Eui Hyun, Park, Su-Hyung, Chang, Jong Hee, Shin, Eui-Cheol · 2019 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentiation Status in Glioblastoma.

Authors: Park, Junsik, Kwon, Minsuk, Kim, Kyung Hwan, Kim, Tae-Shin, Hong, Seon-Hui, Kim, Chang Gon, Kang, Seok-Gu, Moon, Ju Hyung, Kim, Eui Hyun, Park, Su-Hyung, Chang, Jong Hee, Shin, Eui-Cheol

Year: 2019

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-18-2564

Paper The Emerging Role of Surgery for Patients With Advanced Melanoma Treated With Immunotherapy.

Puza, Charles J, Bressler, Elizabeth Schell, Terando, Alicia M, Howard, John Harrison, Brown, Michael C, Hanks, Brent, Salama, April K S, Beasley, Georgia M · 2019 · The Journal of surgical research · DOI

Full title: The Emerging Role of Surgery for Patients With Advanced Melanoma Treated With Immunotherapy.

Authors: Puza, Charles J, Bressler, Elizabeth Schell, Terando, Alicia M, Howard, John Harrison, Brown, Michael C, Hanks, Brent, Salama, April K S, Beasley, Georgia M

Year: 2019

Venue: The Journal of surgical research

DOI: https://doi.org/10.1016/j.jss.2018.11.045

Paper The Relationship Between Response Rate and Survival Benefits in Randomized Immunotherapy Studies.

Jain, Aditi, Stebbing, Justin · 2025 · Cancers · DOI

Full title: The Relationship Between Response Rate and Survival Benefits in Randomized Immunotherapy Studies.

Authors: Jain, Aditi, Stebbing, Justin

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17030495

Paper Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication.

Ali, Omar A, Lewin, Sarah A, Dranoff, Glenn, Mooney, David J · 2016 · Cancer immunology research · DOI

Full title: Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication.

Authors: Ali, Omar A, Lewin, Sarah A, Dranoff, Glenn, Mooney, David J

Year: 2016

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0126

Paper Abstract CT077: Nivolumab (nivo) + ipilimumab (ipi) vs platinum-doublet chemotherapy (PT-DC) as first-line (1L) treatment (tx) for advanced non-small cell lung cancer (NSCLC): initial results from CheckMate 227

Hellmann, Matthew D., Ciuleanu, Tudor–Eliade, Płużański, Adam, Lee, Jong Seok, Otterson, Gregory A., Audigier-Valette, Clarisse, Minenza, Elisa, Linardou, Helena, Burgers, Sjaak, Salman, Pamela, Borghaei, Hossein, Ramalingam, Suresh S., Brahmer, Julie R., Reck, Martin, O’Byrne, Kenneth J., Geese, William J., Green, George, Chang, Han, Szustakowski, Joseph D., Bhagavatheeswaran, Prabhu, Healey, Diane, Fu, Yali, Nathan, Faith E., Paz‐Ares, Luis · 2018 · Cancer Research · DOI

Full title: Abstract CT077: Nivolumab (nivo) + ipilimumab (ipi) vs platinum-doublet chemotherapy (PT-DC) as first-line (1L) treatment (tx) for advanced non-small cell lung cancer (NSCLC): initial results from CheckMate 227

Authors: Hellmann, Matthew D., Ciuleanu, Tudor–Eliade, Płużański, Adam, Lee, Jong Seok, Otterson, Gregory A., Audigier-Valette, Clarisse, Minenza, Elisa, Linardou, Helena, Burgers, Sjaak, Salman, Pamela, Borghaei, Hossein, Ramalingam, Suresh S., Brahmer, Julie R., Reck, Martin, O’Byrne, Kenneth J., Geese, William J., Green, George, Chang, Han, Szustakowski, Joseph D., Bhagavatheeswaran, Prabhu, Healey, Diane, Fu, Yali, Nathan, Faith E., Paz‐Ares, Luis

Year: 2018

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2018-ct077

Paper Immune checkpoint inhibitors for metastatic bladder cancer

Cubelli, Marta, Nunno, Vincenzo Di, Rihawi, Karim, Massari, Francesco · 2017 · Translational Cancer Research · DOI

Full title: Immune checkpoint inhibitors for metastatic bladder cancer

Authors: Cubelli, Marta, Nunno, Vincenzo Di, Rihawi, Karim, Massari, Francesco

Year: 2017

Venue: Translational Cancer Research

DOI: https://doi.org/10.21037/tcr.2017.05.36

Paper Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors

Duraiswamy, Jaikumar, Kaluza, Karen M., Freeman, Gordon J., Coukos, George · 2013 · Cancer Research · DOI

Full title: Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors

Authors: Duraiswamy, Jaikumar, Kaluza, Karen M., Freeman, Gordon J., Coukos, George

Year: 2013

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-12-4100

Paper Evaluation of immune checkpoint inhibitor-associated hepatotoxic adverse events: A pharmacovigilance analysis based on the FAERS database.

Chen, Zhihong, Zhang, Junwei, Zhang, Lei, Liu, Yaoge, Zhang, Ting, Sang, Xinting, Xu, Yiyao, Lu, Xin · 2025 · International journal of immunopathology and pharmacology · DOI

Full title: Evaluation of immune checkpoint inhibitor-associated hepatotoxic adverse events: A pharmacovigilance analysis based on the FAERS database.

Authors: Chen, Zhihong, Zhang, Junwei, Zhang, Lei, Liu, Yaoge, Zhang, Ting, Sang, Xinting, Xu, Yiyao, Lu, Xin

Year: 2025

Venue: International journal of immunopathology and pharmacology

DOI: https://doi.org/10.1177/03946320251343943

Paper Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in mouse models of osteosarcoma.

Hennessy, Marlene, Wahba, Andrew, Felix, Kumar, Cabrera, Mariella, Segura, Maria Gabriela, Kundra, Vikas, Ravoori, Murali K, Stewart, John, Kleinerman, Eugenie S, Jensen, Vanessa Behrana, Gopalakrishnan, Vidya, Pena, Rhoneil, Quach, Phi, Kim, Grace, Kivimäe, Saul, Madakamutil, Loui, Overwijk, Willem W, Zalevsky, Jonathan, Gordon, Nancy · 2021 · International journal of cancer · DOI

Full title: Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in mouse models of osteosarcoma.

Authors: Hennessy, Marlene, Wahba, Andrew, Felix, Kumar, Cabrera, Mariella, Segura, Maria Gabriela, Kundra, Vikas, Ravoori, Murali K, Stewart, John, Kleinerman, Eugenie S, Jensen, Vanessa Behrana, Gopalakrishnan, Vidya, Pena, Rhoneil, Quach, Phi, Kim, Grace, Kivimäe, Saul, Madakamutil, Loui, Overwijk, Willem W, Zalevsky, Jonathan, Gordon, Nancy

Year: 2021

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.33382

Paper Development of cancer immunotherapy based on PD-1/PD-L1 pathway blockade.

Zhang, Min, Liu, Kehai, Wang, Mingfu · 2019 · RSC advances · DOI

Full title: Development of cancer immunotherapy based on PD-1/PD-L1 pathway blockade.

Authors: Zhang, Min, Liu, Kehai, Wang, Mingfu

Year: 2019

Venue: RSC advances

DOI: https://doi.org/10.1039/c9ra04590b

Paper Checkpoint Inhibitor Colitis Shows Drug-Specific Differences in Immune Cell Reaction That Overlap With Inflammatory Bowel Disease and Predict Response to Colitis Therapy.

Lo, Ying-Chun, Price, Christina, Blenman, Kim, Patil, Pallavi, Zhang, Xuchen, Robert, Marie E · 2021 · American journal of clinical pathology · DOI

Full title: Checkpoint Inhibitor Colitis Shows Drug-Specific Differences in Immune Cell Reaction That Overlap With Inflammatory Bowel Disease and Predict Response to Colitis Therapy.

Authors: Lo, Ying-Chun, Price, Christina, Blenman, Kim, Patil, Pallavi, Zhang, Xuchen, Robert, Marie E

Year: 2021

Venue: American journal of clinical pathology

DOI: https://doi.org/10.1093/ajcp/aqaa217

Paper Prognostic Significance of CD4+ Tumour Infiltrating Lymphocytes in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors Therapy.

Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Li, Guo-Xiang, Sun, Zhi-Gang, Zhang, Min · 2025 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP · DOI

Full title: Prognostic Significance of CD4+ Tumour Infiltrating Lymphocytes in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors Therapy.

Authors: Zheng, Qi-Ming, Li, Yuan-Yuan, Wang, Ye-Peng, Li, Guo-Xiang, Sun, Zhi-Gang, Zhang, Min

Year: 2025

Venue: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

DOI: https://doi.org/10.29271/jcpsp.2025.03.341

Paper Highly expressed carbohydrate sulfotransferase 11 correlates with unfavorable prognosis and immune evasion of hepatocellular carcinoma

Xiong, Dandan, Li, Jian‐Di, He, Rong‐Quan, Li, Ming‐xuan, Pan, Yanqing, He, X J, Dang, Yi‐Wu, Chen, Gang · 2022 · Cancer Medicine · DOI

Full title: Highly expressed carbohydrate sulfotransferase 11 correlates with unfavorable prognosis and immune evasion of hepatocellular carcinoma

Authors: Xiong, Dandan, Li, Jian‐Di, He, Rong‐Quan, Li, Ming‐xuan, Pan, Yanqing, He, X J, Dang, Yi‐Wu, Chen, Gang

Year: 2022

Venue: Cancer Medicine

DOI: https://doi.org/10.1002/cam4.5186

Paper Advancement of anti‐LAG ‐3 in cancer therapy

Li, Yunong, Ju, Mingyi, Miao, Yuxi, Zhao, Lin, Xing, Lijuan, Wei, Minjie · 2023 · The FASEB Journal · DOI

Full title: Advancement of anti‐LAG ‐3 in cancer therapy

Authors: Li, Yunong, Ju, Mingyi, Miao, Yuxi, Zhao, Lin, Xing, Lijuan, Wei, Minjie

Year: 2023

Venue: The FASEB Journal

DOI: https://doi.org/10.1096/fj.202301018r

Paper Tumor mutational burden as predictive factor of response to immunotherapy

González‐Cao, María, Viteri, Santiago, Karachaliou, Niki, Aguilar, Andrés, Garcia, Juan, Rosell, Rafael · 2018 · Translational Lung Cancer Research · DOI

Full title: Tumor mutational burden as predictive factor of response to immunotherapy

Authors: González‐Cao, María, Viteri, Santiago, Karachaliou, Niki, Aguilar, Andrés, Garcia, Juan, Rosell, Rafael

Year: 2018

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2018.10.03

Paper Abscopal Effects and Immunomodulation in Skin Cancer Therapy.

Nahm, William J, Sakunchotpanit, Goranit, Nambudiri, Vinod E · 2025 · American journal of clinical dermatology · DOI

Full title: Abscopal Effects and Immunomodulation in Skin Cancer Therapy.

Authors: Nahm, William J, Sakunchotpanit, Goranit, Nambudiri, Vinod E

Year: 2025

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-025-00943-x

Paper A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non‐clear‐cell renal cell carcinoma

Conduit, Ciara, Davis, Ian D., Goh, Jeffrey C., Kichenadasse, Ganessan, Gurney, Howard, Harris, Carole A., Pook, David, Krieger, Laurence E., Parnis, Francis, Underhill, Craig, Adams, Diana, Roncolato, Felicia, Joshua, Anthony M., Ferguson, Tom, Prithviraj, Prashanth, Morris, Michelle Frances, Harrison, Michelle, Begbie, Stephen, Hovey, Elizabeth, George, Mathew, Liow, Elizabeth, Link, Emma, McJannett, Margaret, Gedye, Craig, (ANZUP), the Australian and New Zealand Urogenital and Prostate Cancer Trials Group, Investigators, the UNISoN · 2023 · British Journal of Urology · DOI

Full title: A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non‐clear‐cell renal cell carcinoma

Authors: Conduit, Ciara, Davis, Ian D., Goh, Jeffrey C., Kichenadasse, Ganessan, Gurney, Howard, Harris, Carole A., Pook, David, Krieger, Laurence E., Parnis, Francis, Underhill, Craig, Adams, Diana, Roncolato, Felicia, Joshua, Anthony M., Ferguson, Tom, Prithviraj, Prashanth, Morris, Michelle Frances, Harrison, Michelle, Begbie, Stephen, Hovey, Elizabeth, George, Mathew, Liow, Elizabeth, Link, Emma, McJannett, Margaret, Gedye, Craig, (ANZUP), the Australian and New Zealand Urogenital and Prostate Cancer Trials Group, Investigators, the UNISoN

Year: 2023

Venue: British Journal of Urology

DOI: https://doi.org/10.1111/bju.16190

Paper Advanced renal cell cancer combination immunotherapy clinical trial (ARCITECT; HCRN GU 22-587).

Serzan, Michael, Jegede, Opeyemi A., Bilen, Mehmet Asım, Braun, David A., Einstein, David J., Haas, Naomi B., Hammers, Hans J., King, Jennifer, Runcie, Karie, Sosman, Jeffrey A., Sternberg, Cora N., Yang, Yuanquan, Choueiri, Toni K., Signoretti, Sabina, Atkins, Michael B. · 2024 · Journal of Clinical Oncology · DOI

Full title: Advanced renal cell cancer combination immunotherapy clinical trial (ARCITECT; HCRN GU 22-587).

Authors: Serzan, Michael, Jegede, Opeyemi A., Bilen, Mehmet Asım, Braun, David A., Einstein, David J., Haas, Naomi B., Hammers, Hans J., King, Jennifer, Runcie, Karie, Sosman, Jeffrey A., Sternberg, Cora N., Yang, Yuanquan, Choueiri, Toni K., Signoretti, Sabina, Atkins, Michael B.

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.4_suppl.tps492

Paper Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti-CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo.

Duperret, Elizabeth K, Trautz, Aspen, Stoltz, Regina, Patel, Ami, Wise, Megan C, Perales-Puchalt, Alfredo, Smith, Trevor, Broderick, Kate E, Masteller, Emma, Kim, J Joseph, Humeau, Laurent, Muthumani, Kar, Weiner, David B · 2018 · Cancer research · DOI

Full title: Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti-CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo.

Authors: Duperret, Elizabeth K, Trautz, Aspen, Stoltz, Regina, Patel, Ami, Wise, Megan C, Perales-Puchalt, Alfredo, Smith, Trevor, Broderick, Kate E, Masteller, Emma, Kim, J Joseph, Humeau, Laurent, Muthumani, Kar, Weiner, David B

Year: 2018

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1429

Paper Educational Review: Neoadjuvant Approaches to Melanoma.

Sharon, Cimarron E, Karakousis, Giorgos C · 2022 · Annals of surgical oncology · DOI

Full title: Educational Review: Neoadjuvant Approaches to Melanoma.

Authors: Sharon, Cimarron E, Karakousis, Giorgos C

Year: 2022

Venue: Annals of surgical oncology

DOI: https://doi.org/10.1245/s10434-022-12224-6

Paper Immunotherapy in Lung Cancer: Are the Promises of Long-Term Benefit Finally Met?

Kaen, Diego L, Minatta, Nicolas, Russo, Alessandro, Malapelle, Umberto, de Miguel-Pérez, Diego, Rolfo, Christian · 2021 · Advances in experimental medicine and biology · DOI

Full title: Immunotherapy in Lung Cancer: Are the Promises of Long-Term Benefit Finally Met?

Authors: Kaen, Diego L, Minatta, Nicolas, Russo, Alessandro, Malapelle, Umberto, de Miguel-Pérez, Diego, Rolfo, Christian

Year: 2021

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-030-79308-1_4

Paper Current situation of programmed cell death protein 1/programmed cell death ligand 1 inhibitors in advanced triple-negative breast cancer.

Liang, Yuehua, Liu, Xiaoran, Li, Kun, Li, Huiping · 2022 · Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · DOI

Full title: Current situation of programmed cell death protein 1/programmed cell death ligand 1 inhibitors in advanced triple-negative breast cancer.

Authors: Liang, Yuehua, Liu, Xiaoran, Li, Kun, Li, Huiping

Year: 2022

Venue: Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

DOI: https://doi.org/10.21147/j.issn.1000-9604.2022.02.07

Paper [Sarcoid-like granulomatosis in cancer patients treated with immune checkpoints inhibitors].

Faviez, G, Bousquet, E, Rabeau, A, Rouquette, I, Collot, S, Goumarre, C, Meyer, N, Prevot, G, Mazieres, J · 2018 · Revue des maladies respiratoires · DOI

Full title: [Sarcoid-like granulomatosis in cancer patients treated with immune checkpoints inhibitors].

Authors: Faviez, G, Bousquet, E, Rabeau, A, Rouquette, I, Collot, S, Goumarre, C, Meyer, N, Prevot, G, Mazieres, J

Year: 2018

Venue: Revue des maladies respiratoires

DOI: https://doi.org/10.1016/j.rmr.2018.08.003

Paper Dissecting the mechanisms of immune checkpoint therapy

Sharma, Padmanee, Allison, James P. · 2020 · Nature reviews. Immunology · DOI

Full title: Dissecting the mechanisms of immune checkpoint therapy

Authors: Sharma, Padmanee, Allison, James P.

Year: 2020

Venue: Nature reviews. Immunology

DOI: https://doi.org/10.1038/s41577-020-0275-8

Paper [Advances in immunotherapy for neuroendocrine neoplasms].

Zhang, P P, Lu, M, Shen, L · 2021 · Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery · DOI

Full title: [Advances in immunotherapy for neuroendocrine neoplasms].

Authors: Zhang, P P, Lu, M, Shen, L

Year: 2021

Venue: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

DOI: https://doi.org/10.3760/cma.j.cn.441530-20210627-00247

Paper Guiding immunotherapy combinations: Who gets what?

Ferreira, Michelle N, Choe, Jennifer H · 2021 · Advanced drug delivery reviews · DOI

Full title: Guiding immunotherapy combinations: Who gets what?

Authors: Ferreira, Michelle N, Choe, Jennifer H

Year: 2021

Venue: Advanced drug delivery reviews

DOI: https://doi.org/10.1016/j.addr.2021.113962

Paper Immunotherapy in Malignant Pleural Mesothelioma.

de Gooijer, Cornedine J, Borm, Frank J, Scherpereel, Arnaud, Baas, Paul · 2020 · Frontiers in oncology · DOI

Full title: Immunotherapy in Malignant Pleural Mesothelioma.

Authors: de Gooijer, Cornedine J, Borm, Frank J, Scherpereel, Arnaud, Baas, Paul

Year: 2020

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2020.00187

Paper Immune checkpoint inhibition in ovarian cancer.

Hamanishi, Junzo, Mandai, Masaki, Konishi, Ikuo · 2016 · International immunology · DOI

Full title: Immune checkpoint inhibition in ovarian cancer.

Authors: Hamanishi, Junzo, Mandai, Masaki, Konishi, Ikuo

Year: 2016

Venue: International immunology

DOI: https://doi.org/10.1093/intimm/dxw020

Paper Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade.

House, Imran G, Savas, Peter, Lai, Junyun, Chen, Amanda X Y, Oliver, Amanda J, Teo, Zhi L, Todd, Kirsten L, Henderson, Melissa A, Giuffrida, Lauren, Petley, Emma V, Sek, Kevin, Mardiana, Sherly, Gide, Tuba N, Quek, Camelia, Scolyer, Richard A, Long, Georgina V, Wilmott, James S, Loi, Sherene, Darcy, Phillip K, Beavis, Paul A · 2020 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade.

Authors: House, Imran G, Savas, Peter, Lai, Junyun, Chen, Amanda X Y, Oliver, Amanda J, Teo, Zhi L, Todd, Kirsten L, Henderson, Melissa A, Giuffrida, Lauren, Petley, Emma V, Sek, Kevin, Mardiana, Sherly, Gide, Tuba N, Quek, Camelia, Scolyer, Richard A, Long, Georgina V, Wilmott, James S, Loi, Sherene, Darcy, Phillip K, Beavis, Paul A

Year: 2020

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1868

Paper Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1.

Simeone, Ester, Ascierto, Paolo A · 2012 · Journal of immunotoxicology · DOI

Full title: Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1.

Authors: Simeone, Ester, Ascierto, Paolo A

Year: 2012

Venue: Journal of immunotoxicology

DOI: https://doi.org/10.3109/1547691X.2012.678021

Paper Immuno-regulatory antibodies for the treatment of cancer.

Honeychurch, Jamie, Cheadle, Eleanor J, Dovedi, Simon J, Illidge, Timothy M · 2015 · Expert opinion on biological therapy · DOI

Full title: Immuno-regulatory antibodies for the treatment of cancer.

Authors: Honeychurch, Jamie, Cheadle, Eleanor J, Dovedi, Simon J, Illidge, Timothy M

Year: 2015

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1517/14712598.2015.1036737

Paper [Rheumatic immune adverse events related to immune checkpoint inhibitors-(IrAEs related to ICI)].

Tingry, Thomas, Massy, Emmanuel, Piperno, Muriel, Auroux, Maxime, Kostine, Marie, Maillet, Denis, Amini-Adle, Mona, Fabien, Nicole, Estublier, Charline, Goncalves, David, Girard, Nicolas, Confavreux, Cyrille B · 2021 · Bulletin du cancer · DOI

Full title: [Rheumatic immune adverse events related to immune checkpoint inhibitors-(IrAEs related to ICI)].

Authors: Tingry, Thomas, Massy, Emmanuel, Piperno, Muriel, Auroux, Maxime, Kostine, Marie, Maillet, Denis, Amini-Adle, Mona, Fabien, Nicole, Estublier, Charline, Goncalves, David, Girard, Nicolas, Confavreux, Cyrille B

Year: 2021

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/j.bulcan.2021.01.016

Paper Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs.

Christmas, Brian J, Rafie, Christine I, Hopkins, Alexander C, Scott, Blake A, Ma, Hayley S, Cruz, Kayla A, Woolman, Skylar, Armstrong, Todd D, Connolly, Roisin M, Azad, Nilo A, Jaffee, Elizabeth M, Roussos Torres, Evanthia T · 2018 · Cancer immunology research · DOI

Full title: Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs.

Authors: Christmas, Brian J, Rafie, Christine I, Hopkins, Alexander C, Scott, Blake A, Ma, Hayley S, Cruz, Kayla A, Woolman, Skylar, Armstrong, Todd D, Connolly, Roisin M, Azad, Nilo A, Jaffee, Elizabeth M, Roussos Torres, Evanthia T

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-18-0070

Paper Antitumor Efficacy of a Bispecific Antibody That Targets HER2 and Activates T Cells

Junttila, Teemu T., Li, Ji, Johnston, Jennifer, Hristopoulos, Maria, Clark, Robyn, Ellerman, Diego, Wang, Bu-er, Li, Yijin, Mathieu, Mary, Li, Guangmin, Young, Judy, Luis, Elizabeth, Phillips, Gail D. Lewis, Stefanich, Eric, Spiess, Christoph, Polson, Andrew G., Irving, Bryan, Scheer, Justin M., Junttila, Melissa R., Dennis, Mark S., Kelley, Robert F., Tótpál, Klára, Ebens, Allen · 2014 · Cancer Research · DOI

Full title: Antitumor Efficacy of a Bispecific Antibody That Targets HER2 and Activates T Cells

Authors: Junttila, Teemu T., Li, Ji, Johnston, Jennifer, Hristopoulos, Maria, Clark, Robyn, Ellerman, Diego, Wang, Bu-er, Li, Yijin, Mathieu, Mary, Li, Guangmin, Young, Judy, Luis, Elizabeth, Phillips, Gail D. Lewis, Stefanich, Eric, Spiess, Christoph, Polson, Andrew G., Irving, Bryan, Scheer, Justin M., Junttila, Melissa R., Dennis, Mark S., Kelley, Robert F., Tótpál, Klára, Ebens, Allen

Year: 2014

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-13-3622-t

Paper PD-L1 ≥ 50% lung cancer refractory to PD-1 inhibition: the role of salvage chemo-immunotherapy combination.

Gelsomino, Francesco, Facchinetti, Francesco, Sisi, Monia, Zielli, Teresa, Tiseo, Marcello, Ardizzoni, Andrea · 2021 · Immunotherapy · DOI

Full title: PD-L1 ≥ 50% lung cancer refractory to PD-1 inhibition: the role of salvage chemo-immunotherapy combination.

Authors: Gelsomino, Francesco, Facchinetti, Francesco, Sisi, Monia, Zielli, Teresa, Tiseo, Marcello, Ardizzoni, Andrea

Year: 2021

Venue: Immunotherapy

DOI: https://doi.org/10.2217/imt-2020-0280

Paper Cancer vaccines: Enhanced immunogenic modulation through therapeutic combinations.

Gatti-Mays, Margaret E, Redman, Jason M, Collins, Julie M, Bilusic, Marijo · 2017 · Human vaccines & immunotherapeutics · DOI

Full title: Cancer vaccines: Enhanced immunogenic modulation through therapeutic combinations.

Authors: Gatti-Mays, Margaret E, Redman, Jason M, Collins, Julie M, Bilusic, Marijo

Year: 2017

Venue: Human vaccines & immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2017.1364322

Paper [Immunotherapy of Renal Cell Carcinoma].

Poprach, A, Lakomý, R, Büchler, T · 2017 · Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti · DOI

Full title: [Immunotherapy of Renal Cell Carcinoma].

Authors: Poprach, A, Lakomý, R, Büchler, T

Year: 2017

Venue: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

DOI: https://doi.org/10.14735/amko20173S55

Paper Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites.

Morris, Zachary S, Guy, Emily I, Werner, Lauryn R, Carlson, Peter M, Heinze, Clinton M, Kler, Jasdeep S, Busche, Sara M, Jaquish, Abigail A, Sriramaneni, Raghava N, Carmichael, Lakeesha L, Loibner, Hans, Gillies, Stephen D, Korman, Alan J, Erbe, Amy K, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M · 2018 · Cancer immunology research · DOI

Full title: Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites.

Authors: Morris, Zachary S, Guy, Emily I, Werner, Lauryn R, Carlson, Peter M, Heinze, Clinton M, Kler, Jasdeep S, Busche, Sara M, Jaquish, Abigail A, Sriramaneni, Raghava N, Carmichael, Lakeesha L, Loibner, Hans, Gillies, Stephen D, Korman, Alan J, Erbe, Amy K, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M

Year: 2018

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-17-0353

Paper Measuring tumor mutation burden in non-small cell lung cancer: tissue versus liquid biopsy

Fenizia, Francesca, Pasquale, Raffaella, Roma, Cristin, Bergantino, Francesca, Iannaccone, Alessia, Normanno, Nicola · 2018 · Translational Lung Cancer Research · DOI

Full title: Measuring tumor mutation burden in non-small cell lung cancer: tissue versus liquid biopsy

Authors: Fenizia, Francesca, Pasquale, Raffaella, Roma, Cristin, Bergantino, Francesca, Iannaccone, Alessia, Normanno, Nicola

Year: 2018

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2018.09.23

Paper Tremelimumab for the treatment of hepatocellular carcinoma.

Sogbe, Miguel, Sangro, Paloma, de la Torre-Aláez, Manuel, Sangro, Bruno · 2025 · Expert opinion on biological therapy · DOI

Full title: Tremelimumab for the treatment of hepatocellular carcinoma.

Authors: Sogbe, Miguel, Sangro, Paloma, de la Torre-Aláez, Manuel, Sangro, Bruno

Year: 2025

Venue: Expert opinion on biological therapy

DOI: https://doi.org/10.1080/14712598.2025.2550711

Paper Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade.

Bello, Danielle M, Panageas, Katherine S, Hollmann, Travis, Shoushtari, Alexander N, Momtaz, Parisa, Chapman, Paul B, Postow, Michael A, Callahan, Margaret K, Wolchok, Jedd D, Brady, Mary S, Coit, Daniel G, Ariyan, Charlotte E · 2020 · Annals of surgical oncology · DOI

Full title: Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade.

Authors: Bello, Danielle M, Panageas, Katherine S, Hollmann, Travis, Shoushtari, Alexander N, Momtaz, Parisa, Chapman, Paul B, Postow, Michael A, Callahan, Margaret K, Wolchok, Jedd D, Brady, Mary S, Coit, Daniel G, Ariyan, Charlotte E

Year: 2020

Venue: Annals of surgical oncology

DOI: https://doi.org/10.1245/s10434-019-08099-9

Paper CTLA‑4 blockade combined with 5‑aza‑2'‑deoxycytidine enhances the killing effect of MAGE‑A family common antigen peptide‑specific cytotoxic T cells on breast cancer.

Li, Weijing, Sang, Meixiang, Hao, Xiaoguang, Wu, Yunyan, Shan, Baoen · 2020 · Oncology reports · DOI

Full title: CTLA‑4 blockade combined with 5‑aza‑2'‑deoxycytidine enhances the killing effect of MAGE‑A family common antigen peptide‑specific cytotoxic T cells on breast cancer.

Authors: Li, Weijing, Sang, Meixiang, Hao, Xiaoguang, Wu, Yunyan, Shan, Baoen

Year: 2020

Venue: Oncology reports

DOI: https://doi.org/10.3892/or.2020.7701

Paper Gut microbiota modulation of chemotherapy efficacy and toxicity.

Alexander, James L, Wilson, Ian D, Teare, Julian, Marchesi, Julian R, Nicholson, Jeremy K, Kinross, James M · 2017 · Nature reviews. Gastroenterology & hepatology · DOI

Full title: Gut microbiota modulation of chemotherapy efficacy and toxicity.

Authors: Alexander, James L, Wilson, Ian D, Teare, Julian, Marchesi, Julian R, Nicholson, Jeremy K, Kinross, James M

Year: 2017

Venue: Nature reviews. Gastroenterology & hepatology

DOI: https://doi.org/10.1038/nrgastro.2017.20

Paper Checkpoint inhibitors in squamous cell carcinoma of the head and neck: History and new perspectives.

Sokołowski, Marcin, Chrząszcz, Magdalena, Butrym, Aleksandra · 2025 · Dental and medical problems · DOI

Full title: Checkpoint inhibitors in squamous cell carcinoma of the head and neck: History and new perspectives.

Authors: Sokołowski, Marcin, Chrząszcz, Magdalena, Butrym, Aleksandra

Year: 2025

Venue: Dental and medical problems

DOI: https://doi.org/10.17219/dmp/206913

Paper Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy.

Sckisel, Gail D, Mirsoian, Annie, Bouchlaka, Myriam N, Tietze, Julia K, Chen, Mingyi, Blazar, Bruce R, Murphy, William J · 2015 · Cancer immunology, immunotherapy : CII · DOI

Full title: Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy.

Authors: Sckisel, Gail D, Mirsoian, Annie, Bouchlaka, Myriam N, Tietze, Julia K, Chen, Mingyi, Blazar, Bruce R, Murphy, William J

Year: 2015

Venue: Cancer immunology, immunotherapy : CII

DOI: https://doi.org/10.1007/s00262-015-1759-4

Paper Abstract PR07: Developing syngeneic NOD tumor models to profile immunotoxicity and antitumor immunity in response to cancer immunotherapies in autoimmune-prone mice

A. Young, V. Nguyen, J. Kang, Sadaf Mehdizadeh, Amy Mei, K. Sheehan, D. Serreze, Yi-Guang Chen, R. Schreiber, J. Bluestone · 2019 · Maintenance of Immune Balance: Effects of Targeted and Immune Therapies · DOI

Full title: Abstract PR07: Developing syngeneic NOD tumor models to profile immunotoxicity and antitumor immunity in response to cancer immunotherapies in autoimmune-prone mice

Authors: A. Young, V. Nguyen, J. Kang, Sadaf Mehdizadeh, Amy Mei, K. Sheehan, D. Serreze, Yi-Guang Chen, R. Schreiber, J. Bluestone

Year: 2019

Venue: Maintenance of Immune Balance: Effects of Targeted and Immune Therapies

DOI: https://doi.org/10.1158/2326-6074.cricimteatiaacr18-pr07

Paper [Immune checkpoint inhibitors and allogeneic hematopoietic stem cell transplantation].

Kondo, Eisei, Maeda, Yoshinobu · 2017 · [Rinsho ketsueki] The Japanese journal of clinical hematology · DOI

Full title: [Immune checkpoint inhibitors and allogeneic hematopoietic stem cell transplantation].

Authors: Kondo, Eisei, Maeda, Yoshinobu

Year: 2017

Venue: [Rinsho ketsueki] The Japanese journal of clinical hematology

DOI: https://doi.org/10.11406/rinketsu.58.506

Paper PD-1/PD-L1 Inhibitors Increase Pathological Complete Response in Locally Advanced Gastric Cancer: A Meta-analysis and Trial Sequential Analysis.

de Moraes, Francisco Cezar Aquino, Sano, Vitor Kendi Tsuchiya, Silva, Barbara Lins, Silva, Ana Laura Soares, Castro, Stellanny Cilene Rodrigues, Kreuz, Michele, Fernandes, Lilianne Rodrigues, Kelly, Francinny Alves, Burbano, Rommel Mario Rodríguez · 2025 · Journal of gastrointestinal cancer · DOI

Full title: PD-1/PD-L1 Inhibitors Increase Pathological Complete Response in Locally Advanced Gastric Cancer: A Meta-analysis and Trial Sequential Analysis.

Authors: de Moraes, Francisco Cezar Aquino, Sano, Vitor Kendi Tsuchiya, Silva, Barbara Lins, Silva, Ana Laura Soares, Castro, Stellanny Cilene Rodrigues, Kreuz, Michele, Fernandes, Lilianne Rodrigues, Kelly, Francinny Alves, Burbano, Rommel Mario Rodríguez

Year: 2025

Venue: Journal of gastrointestinal cancer

DOI: https://doi.org/10.1007/s12029-024-01141-4

Paper Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma

Close, Helen J., Stead, Lucy F., Nsengimana, Jérémie, Reilly, Katrina, Droop, Alastair, Wurdak, Heiko, Mathew, Ryan, Corns, Robert, Newton‐Bishop, Julia, Melcher, Alan, Short, Susan, Cook, Graham P., Wilson, Erica · 2019 · Clinical & Experimental Immunology · DOI

Full title: Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma

Authors: Close, Helen J., Stead, Lucy F., Nsengimana, Jérémie, Reilly, Katrina, Droop, Alastair, Wurdak, Heiko, Mathew, Ryan, Corns, Robert, Newton‐Bishop, Julia, Melcher, Alan, Short, Susan, Cook, Graham P., Wilson, Erica

Year: 2019

Venue: Clinical & Experimental Immunology

DOI: https://doi.org/10.1111/cei.13403

Paper Induced PD-L1 expression mediates acquired resistance to agonistic anti-CD40 treatment.

Zippelius, Alfred, Schreiner, Jens, Herzig, Petra, Müller, Philipp · 2015 · Cancer immunology research · DOI

Full title: Induced PD-L1 expression mediates acquired resistance to agonistic anti-CD40 treatment.

Authors: Zippelius, Alfred, Schreiner, Jens, Herzig, Petra, Müller, Philipp

Year: 2015

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-14-0226

Paper Avelumab for the treatment of patients with Merkel cell carcinoma

K. Orlova, N. Petenko, V. Nazarova, L. Demidov · 2020 · Meditsinskiy sovet = Medical Council · DOI

Full title: Avelumab for the treatment of patients with Merkel cell carcinoma

Authors: K. Orlova, N. Petenko, V. Nazarova, L. Demidov

Year: 2020

Venue: Meditsinskiy sovet = Medical Council

DOI: https://doi.org/10.21518/2079-701x-2020-9-94-100

Paper Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade.

Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, He, Shan, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D, Dunn, Joe Dan, Johnson, Jason M, Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R, Ferrarotto, Renata, Garden, Adam S, Fuller, Clifton David, Reddy, Jay, Gross, Neil D, Lango, Miriam N, Leung, Cheuk Hong, Liu, Suyu, Liu, Diane D, Li, Meng, Lee, J Jack, Curran, Michael A, Phan, Jack, Chen, Ken, Gillison, Maura L · 2025 · Cancer discovery · DOI

Full title: Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade.

Authors: Jiang, Xianli, Rudqvist, Nils-Petter, Jiang, Bo, Ye, Shengbin, He, Shan, Liang, Qingnan, Dou, Jinzhuang, Williams, Michelle D, Dunn, Joe Dan, Johnson, Jason M, Akagi, Keiko, Xiao, Weihong, Liang, Shaoheng, Elayavalli, Satvik, Sun, Baohua, Parra, Edwin R, Ferrarotto, Renata, Garden, Adam S, Fuller, Clifton David, Reddy, Jay, Gross, Neil D, Lango, Miriam N, Leung, Cheuk Hong, Liu, Suyu, Liu, Diane D, Li, Meng, Lee, J Jack, Curran, Michael A, Phan, Jack, Chen, Ken, Gillison, Maura L

Year: 2025

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-24-1390

Paper Immune checkpoint inhibitor-associated new-onset hypophysitis: a retrospective analysis using the FAERS.

Lu, Difei, Yao, Jun, Yuan, Geheng, Gao, Ying, Zhang, Junqing, Guo, Xiaohui · 2024 · Endocrine · DOI

Full title: Immune checkpoint inhibitor-associated new-onset hypophysitis: a retrospective analysis using the FAERS.

Authors: Lu, Difei, Yao, Jun, Yuan, Geheng, Gao, Ying, Zhang, Junqing, Guo, Xiaohui

Year: 2024

Venue: Endocrine

DOI: https://doi.org/10.1007/s12020-024-03949-3

Paper A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature.

Ferreira Bruzzi Porto, Helena, C K Lopes, Gabriela, B V Bekierman, Hannah, Altino De Almeida, Sérgio, Da Matta Andreiuolo, Felipe, Lucena, Evandro, Pravin Patel, Sandip, Freire, Vinicius, Herchenhorn, Daniel · 2024 · Case reports in oncology · DOI

Full title: A Complete Response to Combined Immunotherapy in a Patient with an ATM plus SF3B1 Mutation and a Moderate Tumor Mutational Burden with a High-Grade Treatment-Emergent Neuroendocrine Prostate Cancer: Case Report and Review of the Literature.

Authors: Ferreira Bruzzi Porto, Helena, C K Lopes, Gabriela, B V Bekierman, Hannah, Altino De Almeida, Sérgio, Da Matta Andreiuolo, Felipe, Lucena, Evandro, Pravin Patel, Sandip, Freire, Vinicius, Herchenhorn, Daniel

Year: 2024

Venue: Case reports in oncology

DOI: https://doi.org/10.1159/000540573

Paper [Protective effect and mechanism of Lactobacillus rhamnosus on immune checkpoint inhibitors related colitis in mice].

Tan, B, Tang, H, Xu, Y, Chen, M J, Wang, M Z, Qian, J M · 2020 · Zhonghua yi xue za zhi · DOI

Full title: [Protective effect and mechanism of Lactobacillus rhamnosus on immune checkpoint inhibitors related colitis in mice].

Authors: Tan, B, Tang, H, Xu, Y, Chen, M J, Wang, M Z, Qian, J M

Year: 2020

Venue: Zhonghua yi xue za zhi

DOI: https://doi.org/10.3760/cma.j.cn112137-20200520-01598

Paper Immunotherapy for the Treatment of Uveal Melanoma: Current Status and Emerging Therapies.

Komatsubara, Kimberly M, Carvajal, Richard D · 2017 · Current oncology reports · DOI

Full title: Immunotherapy for the Treatment of Uveal Melanoma: Current Status and Emerging Therapies.

Authors: Komatsubara, Kimberly M, Carvajal, Richard D

Year: 2017

Venue: Current oncology reports

DOI: https://doi.org/10.1007/s11912-017-0606-5

Paper Abstract 566: High dimensional single cell analysis predicts response to anti-PD-1 immunotherapy

C. Krieg, M. Nowicka, S. Guglietta, Sabrina Schindler, F. Hartmann, L. Weber, R. Dummer, M. Robinson, M. Levesque, B. Becher · 2018 · Clinical research · DOI

Full title: Abstract 566: High dimensional single cell analysis predicts response to anti-PD-1 immunotherapy

Authors: C. Krieg, M. Nowicka, S. Guglietta, Sabrina Schindler, F. Hartmann, L. Weber, R. Dummer, M. Robinson, M. Levesque, B. Becher

Year: 2018

Venue: Clinical research

DOI: https://doi.org/10.1158/1538-7445.am2018-566

Paper Treatment-related toxicities of immune checkpoint inhibitors in advanced cancers: A meta-analysis.

Man, Johnathan, Ritchie, Georgia, Links, Matthew, Lord, Sally, Lee, Chee Khoon · 2018 · Asia-Pacific journal of clinical oncology · DOI

Full title: Treatment-related toxicities of immune checkpoint inhibitors in advanced cancers: A meta-analysis.

Authors: Man, Johnathan, Ritchie, Georgia, Links, Matthew, Lord, Sally, Lee, Chee Khoon

Year: 2018

Venue: Asia-Pacific journal of clinical oncology

DOI: https://doi.org/10.1111/ajco.12838

Paper [The development status of the next-generation immune checkpoint inhibitors].

Fuse, Masanori, Yoshimura, Kiyoshi · 2017 · Nihon rinsho. Japanese journal of clinical medicine

Full title: [The development status of the next-generation immune checkpoint inhibitors].

Authors: Fuse, Masanori, Yoshimura, Kiyoshi

Year: 2017

Venue: Nihon rinsho. Japanese journal of clinical medicine

Paper CTLA-4 blockade in tumor models: an overview of preclinical and translational research.

Grosso, Joseph F, Jure-Kunkel, Maria N · 2013 · Cancer immunity

Full title: CTLA-4 blockade in tumor models: an overview of preclinical and translational research.

Authors: Grosso, Joseph F, Jure-Kunkel, Maria N

Year: 2013

Venue: Cancer immunity

Paper 325P A phase II, open-label, single-center study of QL1706 plus platinum doublet chemotherapy with or without bevacizumab as first-line treatment in patients with advanced NSCLC: Data from EGFR wild-type cohort

Huang, Yuanyuan, Fang, Weijun, Yang, Yu-Ma, Zhao, Yanbin, Zhao, H., Zhou, Ningjia, Zhang, Y., Chen, L., Zhou, T., Chen, G., Wu, Tongyang, Lu, Ling‐Ying, Xue, Shulin, Zhang, L. · 2022 · Annals of Oncology · DOI

Full title: 325P A phase II, open-label, single-center study of QL1706 plus platinum doublet chemotherapy with or without bevacizumab as first-line treatment in patients with advanced NSCLC: Data from EGFR wild-type cohort

Authors: Huang, Yuanyuan, Fang, Weijun, Yang, Yu-Ma, Zhao, Yanbin, Zhao, H., Zhou, Ningjia, Zhang, Y., Chen, L., Zhou, T., Chen, G., Wu, Tongyang, Lu, Ling‐Ying, Xue, Shulin, Zhang, L.

Year: 2022

Venue: Annals of Oncology

DOI: https://doi.org/10.1016/j.annonc.2022.10.364

Paper Neuroimmunological adverse events associated with immune checkpoint inhibitor: a retrospective, pharmacovigilance study using FAERS database.

Mikami, Takahisa, Liaw, Bobby, Asada, Mizuho, Niimura, Takahiro, Zamami, Yoshito, Green-LaRoche, Deborah, Pai, Lori, Levy, Michael, Jeyapalan, Suriya · 2021 · Journal of neuro-oncology · DOI

Full title: Neuroimmunological adverse events associated with immune checkpoint inhibitor: a retrospective, pharmacovigilance study using FAERS database.

Authors: Mikami, Takahisa, Liaw, Bobby, Asada, Mizuho, Niimura, Takahiro, Zamami, Yoshito, Green-LaRoche, Deborah, Pai, Lori, Levy, Michael, Jeyapalan, Suriya

Year: 2021

Venue: Journal of neuro-oncology

DOI: https://doi.org/10.1007/s11060-020-03687-2

Paper Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors.

Jordi M. Lanis, Matthew S. Lewis, Hannah Strassburger, S. Bagby, Adrian T A Dominguez, J. Marín-Jiménez, R. Pelanda, T. Pitts, J. Lang · 2022 · Journal of Visualized Experiments · DOI

Full title: Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors.

Authors: Jordi M. Lanis, Matthew S. Lewis, Hannah Strassburger, S. Bagby, Adrian T A Dominguez, J. Marín-Jiménez, R. Pelanda, T. Pitts, J. Lang

Year: 2022

Venue: Journal of Visualized Experiments

DOI: https://doi.org/10.3791/64606

Paper Particle Radiation Therapy With Immunotherapy for Advanced Hepatocellular Carcinoma: Emerging Evidence and Remaining Questions

Hatanaka, Takeshi, Shibuya, Kei, Miyasaka, Yuhei, Kakizaki, Satoru, OHNO, TATSUYA · 2026 · Liver International · DOI

Full title: Particle Radiation Therapy With Immunotherapy for Advanced Hepatocellular Carcinoma: Emerging Evidence and Remaining Questions

Authors: Hatanaka, Takeshi, Shibuya, Kei, Miyasaka, Yuhei, Kakizaki, Satoru, OHNO, TATSUYA

Year: 2026

Venue: Liver International

DOI: https://doi.org/10.1111/liv.70555

Paper [Not Available].

Reverdy, Thibaut, Gau, Max, Karabajakian, Andy, Neidhardt, Eve-Marie, Fayette, Jérôme · 2018 · Bulletin du cancer · DOI

Full title: [Not Available].

Authors: Reverdy, Thibaut, Gau, Max, Karabajakian, Andy, Neidhardt, Eve-Marie, Fayette, Jérôme

Year: 2018

Venue: Bulletin du cancer

DOI: https://doi.org/10.1016/S0007-4551(18)30388-6

Paper Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade.

Davila, Eduardo, Kennedy, Richard, Celis, Esteban · 2003 · Cancer research

Full title: Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade.

Authors: Davila, Eduardo, Kennedy, Richard, Celis, Esteban

Year: 2003

Venue: Cancer research

Paper Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab.

D'Angelo, Sandra P, Shoushtari, Alexander N, Keohan, Mary Louise, Dickson, Mark A, Gounder, Mrinal M, Chi, Ping, Loo, Jennifer K, Gaffney, Leigh, Schneider, Lee, Patel, Zarine, Erinjeri, Joseph Patrick, Bluth, Mark J, Sjoberg, Ana, Streicher, Howard, Takebe, Naoko, Qin, Li-Xuan, Antonescu, Cristina, DeMatteo, Ronald P, Carvajal, Richard D, Tap, William D · 2017 · Clinical cancer research : an official journal of the American Association for Cancer Research · DOI

Full title: Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab.

Authors: D'Angelo, Sandra P, Shoushtari, Alexander N, Keohan, Mary Louise, Dickson, Mark A, Gounder, Mrinal M, Chi, Ping, Loo, Jennifer K, Gaffney, Leigh, Schneider, Lee, Patel, Zarine, Erinjeri, Joseph Patrick, Bluth, Mark J, Sjoberg, Ana, Streicher, Howard, Takebe, Naoko, Qin, Li-Xuan, Antonescu, Cristina, DeMatteo, Ronald P, Carvajal, Richard D, Tap, William D

Year: 2017

Venue: Clinical cancer research : an official journal of the American Association for Cancer Research

DOI: https://doi.org/10.1158/1078-0432.CCR-16-2349

Paper Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory head and neck cancer

A. Oweida, M. Hararah, Andy V. Phan, Shilpa Bhatia, S. Lennon, David C Binder, D. Raben, L. Heasley, E. Clambey, R. Nemenoff, S. Karam · 2018 · Immunology · DOI

Full title: Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory head and neck cancer

Authors: A. Oweida, M. Hararah, Andy V. Phan, Shilpa Bhatia, S. Lennon, David C Binder, D. Raben, L. Heasley, E. Clambey, R. Nemenoff, S. Karam

Year: 2018

Venue: Immunology

DOI: https://doi.org/10.1158/1538-7445.am2018-2766

Paper eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

DeNicola, Gina M. · 2023 · DOI

Full title: eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Authors: DeNicola, Gina M.

Year: 2023

DOI: https://doi.org/10.7554/elife.87292.1.sa3

Paper Rechallenge with checkpoint inhibitors in metastatic melanoma.

Reschke, Robin, Ziemer, Mirjana · 2020 · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · DOI

Full title: Rechallenge with checkpoint inhibitors in metastatic melanoma.

Authors: Reschke, Robin, Ziemer, Mirjana

Year: 2020

Venue: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

DOI: https://doi.org/10.1111/ddg.14091

Paper Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone.

Cillo, Anthony R, Kirkwood, John M · 2024 · Cancer cell · DOI

Full title: Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone.

Authors: Cillo, Anthony R, Kirkwood, John M

Year: 2024

Venue: Cancer cell

DOI: https://doi.org/10.1016/j.ccell.2024.08.014

Paper Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice.

Zhu, J, Zou, L, Zhu, S, Mix, E, Shi, F, Wang, H, Volkmann, I, Winblad, B, Schalling, M, Ljunggren, H · 2001 · Journal of neuroimmunology · DOI

Full title: Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice.

Authors: Zhu, J, Zou, L, Zhu, S, Mix, E, Shi, F, Wang, H, Volkmann, I, Winblad, B, Schalling, M, Ljunggren, H

Year: 2001

Venue: Journal of neuroimmunology

DOI: https://doi.org/10.1016/s0165-5728(01)00255-7

Paper 47TCF1+ CD4+ T cells mediate response to anti-CTLA-4 therapy in a sarcomatoid RCC mouse model

Jiang, Hui, Vuong, Lynda, Kuo, Fengshen, Zheng, Doris, Penson, Alex, Zhang, Jing, Gao, Shengyu, Mascareno, Ankur Eduardo, Chen, Ying‐Bei, Khandwala, Yash S., Barbakoff, Daniel, Sanmiguel, Andrea Lopez, Gusella, G. Luca, Li, Ming, Hakimi, A. Ari · 2025 · The Oncologist · DOI

Full title: 47TCF1+ CD4+ T cells mediate response to anti-CTLA-4 therapy in a sarcomatoid RCC mouse model

Authors: Jiang, Hui, Vuong, Lynda, Kuo, Fengshen, Zheng, Doris, Penson, Alex, Zhang, Jing, Gao, Shengyu, Mascareno, Ankur Eduardo, Chen, Ying‐Bei, Khandwala, Yash S., Barbakoff, Daniel, Sanmiguel, Andrea Lopez, Gusella, G. Luca, Li, Ming, Hakimi, A. Ari

Year: 2025

Venue: The Oncologist

DOI: https://doi.org/10.1093/oncolo/oyaf276.048

Paper Pharmacodynamic analysis of an agonistic antibody to the costimulatory receptor GITR

Gordon Moody, J. Moriguchi, Ji-rong Sun, P. McElroy, H. Tan, Yannick Bulliard, Beltran Pedro · 2015 · Journal of Immunotherapy for Cancer · DOI

Full title: Pharmacodynamic analysis of an agonistic antibody to the costimulatory receptor GITR

Authors: Gordon Moody, J. Moriguchi, Ji-rong Sun, P. McElroy, H. Tan, Yannick Bulliard, Beltran Pedro

Year: 2015

Venue: Journal of Immunotherapy for Cancer

DOI: https://doi.org/10.1186/2051-1426-3-s2-p192

Paper A pooled meta-analysis of PD-1/L1 inhibitors incorporation therapy for advanced non-small cell lung cancer.

Wan, Ning, Ji, Bo, Li, Jian, Jiang, Jie, Yang, Chen, Zhang, Tiantian, Huang, Wenjie · 2019 · OncoTargets and therapy · DOI

Full title: A pooled meta-analysis of PD-1/L1 inhibitors incorporation therapy for advanced non-small cell lung cancer.

Authors: Wan, Ning, Ji, Bo, Li, Jian, Jiang, Jie, Yang, Chen, Zhang, Tiantian, Huang, Wenjie

Year: 2019

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S200615

Paper Brain metastases from Merkel cell carcinoma: A nationwide retrospective study.

Caillot, Raphaëlle, Blom, Astrid, Lebbé, Céleste, Da Meda, Laetitia, Boileau, Marie, Dutriaux, Caroline, Guillon, Benoit, Granel-Brocard, Florence, Viguier, Manuelle, Lesage, Candice, Nardin, Charlée, Mansard, Sandrine, Charpentier, Clément, Zehou, Ouidad, Gaudy-Marqueste, Caroline, Legoupil, Delphine, Minart, Benoit, Kieny, Alice, Montaudié, Henri, L'orphelin, Jean-Matthieu, Quéreux, Gaelle, Le Corre, Yannick, Robert, Caroline, Mortier, Laurent, Saiag, Philippe, Samimi, Mahtab · 2025 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Brain metastases from Merkel cell carcinoma: A nationwide retrospective study.

Authors: Caillot, Raphaëlle, Blom, Astrid, Lebbé, Céleste, Da Meda, Laetitia, Boileau, Marie, Dutriaux, Caroline, Guillon, Benoit, Granel-Brocard, Florence, Viguier, Manuelle, Lesage, Candice, Nardin, Charlée, Mansard, Sandrine, Charpentier, Clément, Zehou, Ouidad, Gaudy-Marqueste, Caroline, Legoupil, Delphine, Minart, Benoit, Kieny, Alice, Montaudié, Henri, L'orphelin, Jean-Matthieu, Quéreux, Gaelle, Le Corre, Yannick, Robert, Caroline, Mortier, Laurent, Saiag, Philippe, Samimi, Mahtab

Year: 2025

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2025.115637

Paper Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment

B. Horton, Jason B. Williams, S. Spranger, T. Gajewski · 2015 · Journal of Immunotherapy for Cancer · DOI

Full title: Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment

Authors: B. Horton, Jason B. Williams, S. Spranger, T. Gajewski

Year: 2015

Venue: Journal of Immunotherapy for Cancer

DOI: https://doi.org/10.1186/2051-1426-3-s2-o10

Paper Plasma sPD-L1 and VEGF levels are associated with the prognosis of NSCLC patients treated with combination immunotherapy

Dong, Changhong, Hui, Kaiyuan, Gu, Jie, Wang, Mei, Hu, Chenxi, Jiang, Xiaodong · 2024 · Anti-Cancer Drugs · DOI

Full title: Plasma sPD-L1 and VEGF levels are associated with the prognosis of NSCLC patients treated with combination immunotherapy

Authors: Dong, Changhong, Hui, Kaiyuan, Gu, Jie, Wang, Mei, Hu, Chenxi, Jiang, Xiaodong

Year: 2024

Venue: Anti-Cancer Drugs

DOI: https://doi.org/10.1097/cad.0000000000001576

Paper Clinical heterogeneity of hypophysitis secondary to PD-1/PD-L1 blockade: insights from four cases.

Lupi, Isabella, Brancatella, Alessandro, Cosottini, Mirco, Viola, Nicola, Lanzolla, Giulia, Sgrò, Daniele, Dalmazi, Giulia Di, Latrofa, Francesco, Caturegli, Patrizio, Marcocci, Claudio · 2019 · Endocrinology, diabetes & metabolism case reports · DOI

Full title: Clinical heterogeneity of hypophysitis secondary to PD-1/PD-L1 blockade: insights from four cases.

Authors: Lupi, Isabella, Brancatella, Alessandro, Cosottini, Mirco, Viola, Nicola, Lanzolla, Giulia, Sgrò, Daniele, Dalmazi, Giulia Di, Latrofa, Francesco, Caturegli, Patrizio, Marcocci, Claudio

Year: 2019

Venue: Endocrinology, diabetes & metabolism case reports

DOI: https://doi.org/10.1530/EDM-19-0102

Paper Evidence for Early Stage Anti-Tumor Immunity Elicited by Spatially Fractionated Radiotherapy-Immunotherapy Combinations

Johnsrud, Andrew, Jenkins, Samir V., Jamshidi‐Parsian, Azemat, Quick, Charles M., Galhardo, Edvaldo, Dings, Ruud P.M., Vang, Kieng B., Narayanasamy, Ganesh, Makhoul, Issam, Griffin, Robert J. · 2020 · Radiation Research · DOI

Full title: Evidence for Early Stage Anti-Tumor Immunity Elicited by Spatially Fractionated Radiotherapy-Immunotherapy Combinations

Authors: Johnsrud, Andrew, Jenkins, Samir V., Jamshidi‐Parsian, Azemat, Quick, Charles M., Galhardo, Edvaldo, Dings, Ruud P.M., Vang, Kieng B., Narayanasamy, Ganesh, Makhoul, Issam, Griffin, Robert J.

Year: 2020

Venue: Radiation Research

DOI: https://doi.org/10.1667/rade-20-00065.1

Paper [Endocrinopathies Associated with Immune Checkpoint Inhibitors].

Santos, Maria Joana · 2022 · Acta medica portuguesa · DOI

Full title: [Endocrinopathies Associated with Immune Checkpoint Inhibitors].

Authors: Santos, Maria Joana

Year: 2022

Venue: Acta medica portuguesa

DOI: https://doi.org/10.20344/amp.13673

Paper Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors.

Zhang, Anli, Ren, Zhenhua, Tseng, Kuo-Fu, Liu, Xiaojuan, Li, Huiyu, Lu, Changzheng, Cai, Yueqi, Minna, John D, Fu, Yang-Xin · 2021 · Science translational medicine · DOI

Full title: Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors.

Authors: Zhang, Anli, Ren, Zhenhua, Tseng, Kuo-Fu, Liu, Xiaojuan, Li, Huiyu, Lu, Changzheng, Cai, Yueqi, Minna, John D, Fu, Yang-Xin

Year: 2021

Venue: Science translational medicine

DOI: https://doi.org/10.1126/scitranslmed.abg8693

Paper Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors.

Howell, Ashley V, Gebregziabher, Mulugeta, Thiers, Bruce H, Graboyes, Evan M, Paulos, Chrystal M, Wrangle, John M, Hunt, Kelly J, Wallace, Kristin · 2022 · Journal of geriatric oncology · DOI

Full title: Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors.

Authors: Howell, Ashley V, Gebregziabher, Mulugeta, Thiers, Bruce H, Graboyes, Evan M, Paulos, Chrystal M, Wrangle, John M, Hunt, Kelly J, Wallace, Kristin

Year: 2022

Venue: Journal of geriatric oncology

DOI: https://doi.org/10.1016/j.jgo.2022.05.005

Paper Highlighting novel targets in immunotherapy for liver cancer

Ruff, Samantha M., Shannon, Alexander H., Beane, Joal D., Pawlik, Timothy M. · 2022 · Expert Review of Gastroenterology & Hepatology · DOI

Full title: Highlighting novel targets in immunotherapy for liver cancer

Authors: Ruff, Samantha M., Shannon, Alexander H., Beane, Joal D., Pawlik, Timothy M.

Year: 2022

Venue: Expert Review of Gastroenterology & Hepatology

DOI: https://doi.org/10.1080/17474124.2022.2150841

Paper Insight of pancreatic cancer: recommendations for improving its therapeutic efficacy in the next decade

Xu, Zhihang, Wang, Wenquan, Lou, Wenhui, Liu, Liang · 2022 · Journal of Pancreatology · DOI

Full title: Insight of pancreatic cancer: recommendations for improving its therapeutic efficacy in the next decade

Authors: Xu, Zhihang, Wang, Wenquan, Lou, Wenhui, Liu, Liang

Year: 2022

Venue: Journal of Pancreatology

DOI: https://doi.org/10.1097/jp9.0000000000000093

Paper Regulatory T cell: a protection for tumour cells

Yi Wang, Yushui Ma, Ying Fang, Shengdi Wu, Lili Liu, D. Fu, Xizhong Shen · 2012 · Journal of Cellular and Molecular Medicine · DOI

Full title: Regulatory T cell: a protection for tumour cells

Authors: Yi Wang, Yushui Ma, Ying Fang, Shengdi Wu, Lili Liu, D. Fu, Xizhong Shen

Year: 2012

Venue: Journal of Cellular and Molecular Medicine

DOI: https://doi.org/10.1111/j.1582-4934.2011.01437.x

Paper Neoadjuvant Immunotherapy for Muscle-Invasive Bladder Cancer.

Peyrottes, Arthur, Ouzaid, Idir, Califano, Gianluigi, Hermieu, Jean-Francois, Xylinas, Evanguelos · 2021 · Medicina (Kaunas, Lithuania) · DOI

Full title: Neoadjuvant Immunotherapy for Muscle-Invasive Bladder Cancer.

Authors: Peyrottes, Arthur, Ouzaid, Idir, Califano, Gianluigi, Hermieu, Jean-Francois, Xylinas, Evanguelos

Year: 2021

Venue: Medicina (Kaunas, Lithuania)

DOI: https://doi.org/10.3390/medicina57080769

Paper RaPiDS (GOG-3028): randomized Phase II study of balstilimab alone or in combination with zalifrelimab in cervical cancer.

O'Malley, David M, Randall, Leslie M, Jackson, Camille Gunderson, Coleman, Robert L, Hays, John L, Moore, Kathleen N, Naumann, R Wendel, Rocconi, Rodney P, Slomovitz, Brian M, Tewari, Krishnansu S, Ancukiewicz, Marek, Feliu, Waldo Ortuzar, Monk, Bradley J · 2021 · Future oncology (London, England) · DOI

Full title: RaPiDS (GOG-3028): randomized Phase II study of balstilimab alone or in combination with zalifrelimab in cervical cancer.

Authors: O'Malley, David M, Randall, Leslie M, Jackson, Camille Gunderson, Coleman, Robert L, Hays, John L, Moore, Kathleen N, Naumann, R Wendel, Rocconi, Rodney P, Slomovitz, Brian M, Tewari, Krishnansu S, Ancukiewicz, Marek, Feliu, Waldo Ortuzar, Monk, Bradley J

Year: 2021

Venue: Future oncology (London, England)

DOI: https://doi.org/10.2217/fon-2021-0529

Paper Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts

Capasso, Anna, Lang, Julie, Pitts, Todd M., Jordan, Kimberly R., Lieu, Christopher H., Davis, S. Lindsey, Diamond, Jennifer R., Kopetz, Scott, Barbee, Jacob, Peterson, Jacob N., Freed, Brian M., Yacob, Betelehem W., Bagby, Stacey M., Messersmith, Wells A., Slansky, Jill E., Pelanda, Roberta, Eckhardt, S. Gail · 2019 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts

Authors: Capasso, Anna, Lang, Julie, Pitts, Todd M., Jordan, Kimberly R., Lieu, Christopher H., Davis, S. Lindsey, Diamond, Jennifer R., Kopetz, Scott, Barbee, Jacob, Peterson, Jacob N., Freed, Brian M., Yacob, Betelehem W., Bagby, Stacey M., Messersmith, Wells A., Slansky, Jill E., Pelanda, Roberta, Eckhardt, S. Gail

Year: 2019

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-019-0518-z

Paper Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cell Lung Cancer.

Costantini, Adrien, Cadranel, Jacques · 2018 · Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · DOI

Full title: Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cell Lung Cancer.

Authors: Costantini, Adrien, Cadranel, Jacques

Year: 2018

Venue: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

DOI: https://doi.org/10.1016/j.jtho.2017.11.113

Paper Prognostic implications of tumor associated macrophages (TAMs) in soft tissue sarcoma.

S. Raj, M. Kooshki, Melissa Winters, G. Russell, L. Miller, J. Laurini, T. Pierre, P. Savage · 2019 · Journal of Clinical Oncology · DOI

Full title: Prognostic implications of tumor associated macrophages (TAMs) in soft tissue sarcoma.

Authors: S. Raj, M. Kooshki, Melissa Winters, G. Russell, L. Miller, J. Laurini, T. Pierre, P. Savage

Year: 2019

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2019.37.15_suppl.e22548

Paper Ex Vivo Evaluation of Combination Immunotherapy Using Tumor-Microenvironment-on-Chip.

Mu, Hsuan-Yu, Lin, Chiao-Min, Chu, Li-An, Lin, Ya-Hui, Li, Ji, Liu, Chao-Yu, Huang, Hsi-Chien, Cheng, Sheng-Liang, Lee, Tsung-Ying, Lee, Hsin Mei, Chen, Hsin-Min, Tsai, Yun-Jen, Chen, Yunching, Huang, Jen-Huang · 2024 · Advanced healthcare materials · DOI

Full title: Ex Vivo Evaluation of Combination Immunotherapy Using Tumor-Microenvironment-on-Chip.

Authors: Mu, Hsuan-Yu, Lin, Chiao-Min, Chu, Li-An, Lin, Ya-Hui, Li, Ji, Liu, Chao-Yu, Huang, Hsi-Chien, Cheng, Sheng-Liang, Lee, Tsung-Ying, Lee, Hsin Mei, Chen, Hsin-Min, Tsai, Yun-Jen, Chen, Yunching, Huang, Jen-Huang

Year: 2024

Venue: Advanced healthcare materials

DOI: https://doi.org/10.1002/adhm.202302268

Paper Recent Advances in Systemic Therapies for Advanced Hepatocellular Carcinoma

Aitcheson, Gabriella, Pillai, Anjana, Dahman, Bassam, John, Binu V. · 2021 · Current Hepatology Reports · DOI

Full title: Recent Advances in Systemic Therapies for Advanced Hepatocellular Carcinoma

Authors: Aitcheson, Gabriella, Pillai, Anjana, Dahman, Bassam, John, Binu V.

Year: 2021

Venue: Current Hepatology Reports

DOI: https://doi.org/10.1007/s11901-021-00560-2

Paper A phase 1/2 study of favezelimab in combination with pembrolizumab for anti–PD-1–naive relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL): An updated analysis.

John M Timmerman, D. Lavie, Borchmann Peter, Gareth P Gregory, A. Herrera, Leonard Minuk, V. Vučinić, P. Armand, A. Avigdor, R. Gasiorowski, Y. Herishanu, C. Keane, J. Kuruvilla, Rachel Marceau West, P. Pillai, P. Marinello, Nathalie A. Johnson · 2024 · Journal of Clinical Oncology · DOI

Full title: A phase 1/2 study of favezelimab in combination with pembrolizumab for anti–PD-1–naive relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL): An updated analysis.

Authors: John M Timmerman, D. Lavie, Borchmann Peter, Gareth P Gregory, A. Herrera, Leonard Minuk, V. Vučinić, P. Armand, A. Avigdor, R. Gasiorowski, Y. Herishanu, C. Keane, J. Kuruvilla, Rachel Marceau West, P. Pillai, P. Marinello, Nathalie A. Johnson

Year: 2024

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2024.42.16_suppl.7055

Paper Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

Appelbaum, Jacob, Wells, David J., Hiatt, Joseph B., Steinbach, Gideon, Stewart, F. Marc, Thomas, Hannah, Nghiem, Paul, Kapur, Raj P., Thompson, John A., Bhatia, Shailender · 2018 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

Authors: Appelbaum, Jacob, Wells, David J., Hiatt, Joseph B., Steinbach, Gideon, Stewart, F. Marc, Thomas, Hannah, Nghiem, Paul, Kapur, Raj P., Thompson, John A., Bhatia, Shailender

Year: 2018

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-018-0396-9

Paper Anti-PD1 following ipilimumab for mucosal melanoma: durable tumor response associated with severe hypothyroidism and rhabdomyolysis.

Min, Le, Hodi, F Stephen · 2014 · Cancer immunology research · DOI

Full title: Anti-PD1 following ipilimumab for mucosal melanoma: durable tumor response associated with severe hypothyroidism and rhabdomyolysis.

Authors: Min, Le, Hodi, F Stephen

Year: 2014

Venue: Cancer immunology research

DOI: https://doi.org/10.1158/2326-6066.CIR-13-0146

Paper Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

Hoefsmit, Esmée P, Rozeman, Elisa A, Haanen, John B A G, Blank, Christian U · 2019 · ESMO open · DOI

Full title: Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

Authors: Hoefsmit, Esmée P, Rozeman, Elisa A, Haanen, John B A G, Blank, Christian U

Year: 2019

Venue: ESMO open

DOI: https://doi.org/10.1136/esmoopen-2018-000472

Paper Update on immune checkpoint inhibitors in lung cancer.

Creelan, Benjamin C · 2014 · Cancer control : journal of the Moffitt Cancer Center · DOI

Full title: Update on immune checkpoint inhibitors in lung cancer.

Authors: Creelan, Benjamin C

Year: 2014

Venue: Cancer control : journal of the Moffitt Cancer Center

DOI: https://doi.org/10.1177/107327481402100112

Paper Optimal management of immune-related adverse events resulting from treatment with immune checkpoint inhibitors: a review and update

Nagai, Hiroki, Muto, Manabu · 2018 · International Journal of Clinical Oncology · DOI

Full title: Optimal management of immune-related adverse events resulting from treatment with immune checkpoint inhibitors: a review and update

Authors: Nagai, Hiroki, Muto, Manabu

Year: 2018

Venue: International Journal of Clinical Oncology

DOI: https://doi.org/10.1007/s10147-018-1259-6

Paper Neoadjuvant therapy for triple-negative breast cancer: potential predictive biomarkers of activity and efficacy of platinum chemotherapy, PARP- and immune-checkpoint-inhibitors.

Garufi, Giovanna, Palazzo, Antonella, Paris, Ida, Orlandi, Armando, Cassano, Alessandra, Tortora, Giampaolo, Scambia, Giovanni, Bria, Emilio, Carbognin, Luisa · 2020 · Expert opinion on pharmacotherapy · DOI

Full title: Neoadjuvant therapy for triple-negative breast cancer: potential predictive biomarkers of activity and efficacy of platinum chemotherapy, PARP- and immune-checkpoint-inhibitors.

Authors: Garufi, Giovanna, Palazzo, Antonella, Paris, Ida, Orlandi, Armando, Cassano, Alessandra, Tortora, Giampaolo, Scambia, Giovanni, Bria, Emilio, Carbognin, Luisa

Year: 2020

Venue: Expert opinion on pharmacotherapy

DOI: https://doi.org/10.1080/14656566.2020.1724957

Paper T cell checkpoint regulators in the heart.

Grabie, Nir, Lichtman, Andrew H, Padera, Robert · 2019 · Cardiovascular research · DOI

Full title: T cell checkpoint regulators in the heart.

Authors: Grabie, Nir, Lichtman, Andrew H, Padera, Robert

Year: 2019

Venue: Cardiovascular research

DOI: https://doi.org/10.1093/cvr/cvz025

Paper Abstract OT1-18-04: A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC)

D. Page, Krystle L Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, M. Martel, Yaping Wu, N. Moxon, S. Mellinger, W. Urba, T. Traina, A. Gucalp · 2022 · Cancer Research · DOI

Full title: Abstract OT1-18-04: A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC)

Authors: D. Page, Krystle L Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, M. Martel, Yaping Wu, N. Moxon, S. Mellinger, W. Urba, T. Traina, A. Gucalp

Year: 2022

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.sabcs21-ot1-18-04

Paper Pan-Cancer Landscape of B- and T-Lymphocyte Attenuator: Implications for Potential Immunotherapy Combinations.

Nishizaki, Daisuke, Choi, Sharon, Pandya, Chinmayi, Lee, Suzanna, Pabla, Sarabjot, DePietro, Paul, Jensen, Taylor J, Kurzrock, Razelle, Kato, Shumei · 2025 · JCO precision oncology · DOI

Full title: Pan-Cancer Landscape of B- and T-Lymphocyte Attenuator: Implications for Potential Immunotherapy Combinations.

Authors: Nishizaki, Daisuke, Choi, Sharon, Pandya, Chinmayi, Lee, Suzanna, Pabla, Sarabjot, DePietro, Paul, Jensen, Taylor J, Kurzrock, Razelle, Kato, Shumei

Year: 2025

Venue: JCO precision oncology

DOI: https://doi.org/10.1200/PO-25-00304

Paper The landscape of immune checkpoints expression in non-small cell lung cancer: a narrative review.

Liu, Yu, Chen, Peixin, Wang, Hao, Wu, Shengyu, Zhao, Sha, He, Yayi, Zhou, Caicun, Hirsch, Fred R · 2021 · Translational lung cancer research · DOI

Full title: The landscape of immune checkpoints expression in non-small cell lung cancer: a narrative review.

Authors: Liu, Yu, Chen, Peixin, Wang, Hao, Wu, Shengyu, Zhao, Sha, He, Yayi, Zhou, Caicun, Hirsch, Fred R

Year: 2021

Venue: Translational lung cancer research

DOI: https://doi.org/10.21037/tlcr-20-1019

Paper Association of Immune-Related Adverse Events, Hospitalization, and Therapy Resumption With Survival Among Patients With Metastatic Melanoma Receiving Single-Agent or Combination Immunotherapy

Watson, Alexander, Goutam, Siddhartha, Stukalin, Igor, Ewanchuk, Benjamin W., Sander, Michael, Meyers, Daniel E., Pabani, Aliyah, Cheung, Winson Y., Heng, Daniel Y.C., Cheng, Tina, Monzon, Jose Gerard, Navani, Vishal · 2022 · JAMA Network Open · DOI

Full title: Association of Immune-Related Adverse Events, Hospitalization, and Therapy Resumption With Survival Among Patients With Metastatic Melanoma Receiving Single-Agent or Combination Immunotherapy

Authors: Watson, Alexander, Goutam, Siddhartha, Stukalin, Igor, Ewanchuk, Benjamin W., Sander, Michael, Meyers, Daniel E., Pabani, Aliyah, Cheung, Winson Y., Heng, Daniel Y.C., Cheng, Tina, Monzon, Jose Gerard, Navani, Vishal

Year: 2022

Venue: JAMA Network Open

DOI: https://doi.org/10.1001/jamanetworkopen.2022.45596

Paper Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes and Outcomes in Anti-PD-1-Based Treated Melanoma.

Schuiveling, Mark, van Duin, Isabella A J, Ter Maat, Laurens S, van der Weerd, Janneke C, Verheijden, Rik J, van den Berkmortel, Franchette, Blank, Christian U, Breimer, Gerben E, Burgers, Femke H, Boers-Sonderen, Marye, van den Eertwegh, Alfons J M, de Groot, Jan Willem B, Haanen, John B A G, Hospers, Geke A P, Kapiteijn, Ellen, Piersma, Djura, Vreugdenhil, Gerard, Westgeest, Hans, Schrader, Anne M R, Pluim, Josien P W, van Diest, Paul J, Veta, Mitko, Suijkerbuijk, Karijn P M, Blokx, Willeke A M · 2025 · JAMA oncology · DOI

Full title: Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes and Outcomes in Anti-PD-1-Based Treated Melanoma.

Authors: Schuiveling, Mark, van Duin, Isabella A J, Ter Maat, Laurens S, van der Weerd, Janneke C, Verheijden, Rik J, van den Berkmortel, Franchette, Blank, Christian U, Breimer, Gerben E, Burgers, Femke H, Boers-Sonderen, Marye, van den Eertwegh, Alfons J M, de Groot, Jan Willem B, Haanen, John B A G, Hospers, Geke A P, Kapiteijn, Ellen, Piersma, Djura, Vreugdenhil, Gerard, Westgeest, Hans, Schrader, Anne M R, Pluim, Josien P W, van Diest, Paul J, Veta, Mitko, Suijkerbuijk, Karijn P M, Blokx, Willeke A M

Year: 2025

Venue: JAMA oncology

DOI: https://doi.org/10.1001/jamaoncol.2025.4072

Paper D-dimer levels predict the treatment efficacy and prognosis of esophageal squamous cell carcinoma treated with PD-1/PD-L1 inhibitors.

Wu, Yuchen, Liu, Xin, Li, Huihui, Wang, Wenjing, Ye, Lisha, Zhou, Yun, Chen, Da · 2024 · The International journal of biological markers · DOI

Full title: D-dimer levels predict the treatment efficacy and prognosis of esophageal squamous cell carcinoma treated with PD-1/PD-L1 inhibitors.

Authors: Wu, Yuchen, Liu, Xin, Li, Huihui, Wang, Wenjing, Ye, Lisha, Zhou, Yun, Chen, Da

Year: 2024

Venue: The International journal of biological markers

DOI: https://doi.org/10.1177/03936155241262045

Paper Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.

van der Leun, Anne M, Traets, Joleen J H, Vos, Joris L, Elbers, Joris B W, Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S, Haanen, John B A G, Schumacher, Ton N M, Zuur, Charlotte L · 2023 · Cancer discovery · DOI

Full title: Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.

Authors: van der Leun, Anne M, Traets, Joleen J H, Vos, Joris L, Elbers, Joris B W, Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S, Haanen, John B A G, Schumacher, Ton N M, Zuur, Charlotte L

Year: 2023

Venue: Cancer discovery

DOI: https://doi.org/10.1158/2159-8290.CD-22-0851

Paper Enhanced tumor eradication by combining CTLA-4 or PD-1 blockade with CpG therapy.

Mangsbo, Sara M, Sandin, Linda C, Anger, Kerstin, Korman, Alan J, Loskog, Angelica, Tötterman, Thomas H · 2010 · Journal of immunotherapy (Hagerstown, Md. : 1997) · DOI

Full title: Enhanced tumor eradication by combining CTLA-4 or PD-1 blockade with CpG therapy.

Authors: Mangsbo, Sara M, Sandin, Linda C, Anger, Kerstin, Korman, Alan J, Loskog, Angelica, Tötterman, Thomas H

Year: 2010

Venue: Journal of immunotherapy (Hagerstown, Md. : 1997)

DOI: https://doi.org/10.1097/CJI.0b013e3181c01fcb

Paper Prevalence of Epstein-Barr Virus Infection and Mismatch Repair Protein Deficiency and the Correlation of Immune Markers in Tibetan Patients with Gastric Cancer.

Shi, Jie, Yang, Xu, Wang, Xinmei, Luo, Yufeng, Zhou, Weixun, Luo, Hanhuan, Bianba, Zhaxi, Nima, Zhuoma, Wang, Qian, Wang, Han, Liao, Ruiqian, Ciren, Quzhen, Li, Mei, Pang, Junyi · 2022 · BioMed research international · DOI

Full title: Prevalence of Epstein-Barr Virus Infection and Mismatch Repair Protein Deficiency and the Correlation of Immune Markers in Tibetan Patients with Gastric Cancer.

Authors: Shi, Jie, Yang, Xu, Wang, Xinmei, Luo, Yufeng, Zhou, Weixun, Luo, Hanhuan, Bianba, Zhaxi, Nima, Zhuoma, Wang, Qian, Wang, Han, Liao, Ruiqian, Ciren, Quzhen, Li, Mei, Pang, Junyi

Year: 2022

Venue: BioMed research international

DOI: https://doi.org/10.1155/2022/2684065

Paper Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance

Bagchi, Sreya, Yuan, Robert, Engleman, Edgar G. · 2020 · Annual Review of Pathology Mechanisms of Disease · DOI

Full title: Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance

Authors: Bagchi, Sreya, Yuan, Robert, Engleman, Edgar G.

Year: 2020

Venue: Annual Review of Pathology Mechanisms of Disease

DOI: https://doi.org/10.1146/annurev-pathol-042020-042741

Paper Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma.

Lussier, Danielle M, Johnson, John L, Hingorani, Pooja, Blattman, Joseph N · 2015 · Journal for immunotherapy of cancer · DOI

Full title: Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma.

Authors: Lussier, Danielle M, Johnson, John L, Hingorani, Pooja, Blattman, Joseph N

Year: 2015

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-015-0067-z

Paper Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs.

Gilardi, Mara, Saddawi-Konefka, Robert, Wu, Victoria H, Lopez-Ramirez, Miguel Angel, Wang, Zhiyong, Soto, Fernando, Ramms, Dana J, Proietto, Marco, Mikulski, Zbigniew, Miki, Haruka, Sharabi, Andrew, Kupor, Daniel, Rueda, Ricardo, Hollern, Daniel P, Wang, Joseph, Gutkind, J Silvio · 2022 · Molecular cancer therapeutics · DOI

Full title: Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs.

Authors: Gilardi, Mara, Saddawi-Konefka, Robert, Wu, Victoria H, Lopez-Ramirez, Miguel Angel, Wang, Zhiyong, Soto, Fernando, Ramms, Dana J, Proietto, Marco, Mikulski, Zbigniew, Miki, Haruka, Sharabi, Andrew, Kupor, Daniel, Rueda, Ricardo, Hollern, Daniel P, Wang, Joseph, Gutkind, J Silvio

Year: 2022

Venue: Molecular cancer therapeutics

DOI: https://doi.org/10.1158/1535-7163.MCT-21-0234

Paper CD8+ T cell exhaustion and cancer immunotherapy.

Wang, Qingda, Qin, Yang, Li, Bo · 2023 · Cancer letters · DOI

Full title: CD8+ T cell exhaustion and cancer immunotherapy.

Authors: Wang, Qingda, Qin, Yang, Li, Bo

Year: 2023

Venue: Cancer letters

DOI: https://doi.org/10.1016/j.canlet.2022.216043

Paper Melanoma Brain Metastases: An Update on the Use of Immune Checkpoint Inhibitors and Molecularly Targeted Agents.

Moschos, Stergios J · 2022 · American journal of clinical dermatology · DOI

Full title: Melanoma Brain Metastases: An Update on the Use of Immune Checkpoint Inhibitors and Molecularly Targeted Agents.

Authors: Moschos, Stergios J

Year: 2022

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-022-00678-z

Paper Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy.

Eschweiler, Simon, Clarke, James, Ramírez-Suástegui, Ciro, Panwar, Bharat, Madrigal, Ariel, Chee, Serena J, Karydis, Ioannis, Woo, Edwin, Alzetani, Aiman, Elsheikh, Somaia, Hanley, C J, Thomas, G J, Friedmann, Peter S, Sanchez-Elsner, Tilman, Ay, Ferhat, Ottensmeier, Christian H, Vijayanand, Pandurangan · 2021 · Nature immunology · DOI

Full title: Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy.

Authors: Eschweiler, Simon, Clarke, James, Ramírez-Suástegui, Ciro, Panwar, Bharat, Madrigal, Ariel, Chee, Serena J, Karydis, Ioannis, Woo, Edwin, Alzetani, Aiman, Elsheikh, Somaia, Hanley, C J, Thomas, G J, Friedmann, Peter S, Sanchez-Elsner, Tilman, Ay, Ferhat, Ottensmeier, Christian H, Vijayanand, Pandurangan

Year: 2021

Venue: Nature immunology

DOI: https://doi.org/10.1038/s41590-021-00958-6

Paper Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Colli, Leandro M., Machiela, Mitchell J., Zhang, Han, Myers, Timothy A., Jessop, Lea, Delattre, Olivier, Yu, Kai, Chanock, Stephen J. · 2017 · Cancer Research · DOI

Full title: Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Authors: Colli, Leandro M., Machiela, Mitchell J., Zhang, Han, Myers, Timothy A., Jessop, Lea, Delattre, Olivier, Yu, Kai, Chanock, Stephen J.

Year: 2017

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-16-3338

Paper Advancements in Stimulus-Responsive Co-Delivery Nanocarriers for Enhanced Cancer Immunotherapy.

Zhang, Meng-Ru, Fang, Lin-Lin, Guo, Yang, Wang, Qin, Li, You-Jie, Sun, Hong-Fang, Xie, Shu-Yang, Liang, Yan · 2024 · International journal of nanomedicine · DOI

Full title: Advancements in Stimulus-Responsive Co-Delivery Nanocarriers for Enhanced Cancer Immunotherapy.

Authors: Zhang, Meng-Ru, Fang, Lin-Lin, Guo, Yang, Wang, Qin, Li, You-Jie, Sun, Hong-Fang, Xie, Shu-Yang, Liang, Yan

Year: 2024

Venue: International journal of nanomedicine

DOI: https://doi.org/10.2147/IJN.S454004

Paper A robust response to combination immune checkpoint inhibitor therapy in HPV-related small cell cancer: a case report

Ho, Won Jin, Rooper, Lisa M., Sagorsky, Sarah, Kang, Hyunseok · 2018 · Journal for ImmunoTherapy of Cancer · DOI

Full title: A robust response to combination immune checkpoint inhibitor therapy in HPV-related small cell cancer: a case report

Authors: Ho, Won Jin, Rooper, Lisa M., Sagorsky, Sarah, Kang, Hyunseok

Year: 2018

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1186/s40425-018-0348-4

Paper Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.

Pilon-Thomas, Shari, Kodumudi, Krithika N, El-Kenawi, Asmaa E, Russell, Shonagh, Weber, Amy M, Luddy, Kimberly, Damaghi, Mehdi, Wojtkowiak, Jonathan W, Mulé, James J, Ibrahim-Hashim, Arig, Gillies, Robert J · 2016 · Cancer research · DOI

Full title: Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.

Authors: Pilon-Thomas, Shari, Kodumudi, Krithika N, El-Kenawi, Asmaa E, Russell, Shonagh, Weber, Amy M, Luddy, Kimberly, Damaghi, Mehdi, Wojtkowiak, Jonathan W, Mulé, James J, Ibrahim-Hashim, Arig, Gillies, Robert J

Year: 2016

Venue: Cancer research

DOI: https://doi.org/10.1158/0008-5472.CAN-15-1743

Paper Combination of CTLA-4 and PD-1 blockers for treatment of cancer.

Rotte, Anand · 2019 · Journal of experimental & clinical cancer research : CR · DOI

Full title: Combination of CTLA-4 and PD-1 blockers for treatment of cancer.

Authors: Rotte, Anand

Year: 2019

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-019-1259-z

Paper Tumor Lysate‐Loaded Lipid Hybrid Nanovaccine Collaborated with an Immune Checkpoint Antagonist for Combination Immunotherapy

Xiaomeng Hu, Tingting Wu, Xianya Qin, Yan Qi, Qi Qiao, Conglian Yang, Zhiping Zhang · 2018 · Advanced Healthcare Materials · DOI

Full title: Tumor Lysate‐Loaded Lipid Hybrid Nanovaccine Collaborated with an Immune Checkpoint Antagonist for Combination Immunotherapy

Authors: Xiaomeng Hu, Tingting Wu, Xianya Qin, Yan Qi, Qi Qiao, Conglian Yang, Zhiping Zhang

Year: 2018

Venue: Advanced Healthcare Materials

DOI: https://doi.org/10.1002/adhm.201800837

Paper Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy.

Liu, Xin, Le Gall, Camille, Alexander, Ryan K, Borgman, Ella, Balligand, Thomas, Ploegh, Hidde L · 2026 · Nature biomedical engineering · DOI

Full title: Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy.

Authors: Liu, Xin, Le Gall, Camille, Alexander, Ryan K, Borgman, Ella, Balligand, Thomas, Ploegh, Hidde L

Year: 2026

Venue: Nature biomedical engineering

DOI: https://doi.org/10.1038/s41551-025-01447-z

Paper Akt inhibition enhances the antitumor efficacy of immune checkpoint blockades and radiotherapy in a syngeneic breast cancer model.

Park, Nawon, Jeon, Seung Hyuck, Kim, Yoomin, Kim, Seongmin, Kim, In Ah · 2025 · Molecular therapy. Oncology · DOI

Full title: Akt inhibition enhances the antitumor efficacy of immune checkpoint blockades and radiotherapy in a syngeneic breast cancer model.

Authors: Park, Nawon, Jeon, Seung Hyuck, Kim, Yoomin, Kim, Seongmin, Kim, In Ah

Year: 2025

Venue: Molecular therapy. Oncology

DOI: https://doi.org/10.1016/j.omton.2025.201087

Paper Immunotherapy for esophageal cancer: Where are we now and where can we go.

Shoji, Yoshiaki, Koyanagi, Kazuo, Kanamori, Kohei, Tajima, Kohei, Ogimi, Mika, Ninomiya, Yamato, Yamamoto, Miho, Kazuno, Akihito, Nabeshima, Kazuhito, Nishi, Takayuki, Mori, Masaki · 2024 · World journal of gastroenterology · DOI

Full title: Immunotherapy for esophageal cancer: Where are we now and where can we go.

Authors: Shoji, Yoshiaki, Koyanagi, Kazuo, Kanamori, Kohei, Tajima, Kohei, Ogimi, Mika, Ninomiya, Yamato, Yamamoto, Miho, Kazuno, Akihito, Nabeshima, Kazuhito, Nishi, Takayuki, Mori, Masaki

Year: 2024

Venue: World journal of gastroenterology

DOI: https://doi.org/10.3748/wjg.v30.i19.2496

Paper Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer

Liu, Jing, Blake, Stephen J., Harjunpää, Heidi, Fairfax, Kirsten A., Yong, Michelle C.R., Allen, Stacey, Kohrt, Holbrook E., Takeda, Kazuyoshi, Smyth, Mark J., Teng, Michele W.L. · 2016 · Cancer Research · DOI

Full title: Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer

Authors: Liu, Jing, Blake, Stephen J., Harjunpää, Heidi, Fairfax, Kirsten A., Yong, Michelle C.R., Allen, Stacey, Kohrt, Holbrook E., Takeda, Kazuyoshi, Smyth, Mark J., Teng, Michele W.L.

Year: 2016

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-16-0194

Paper Phase I dose escalation trial of STX-001, an LNP-encapsulated self-replicating mRNA expressing IL-12, in patients (pts) with advanced solid tumors.

S. Piha-Paul, K. Sankhala, A. Menzies, Madhuri Dey, Julian Quiñones, Ryan T. Sowell, Prashant R. Nambiar, Robert W Shine, Katherine Kacena, S. Thomas, L. Ali, Neil Sankar, T. Kitada, J. Luke, G. V. Long · 2025 · Journal of Clinical Oncology · DOI

Full title: Phase I dose escalation trial of STX-001, an LNP-encapsulated self-replicating mRNA expressing IL-12, in patients (pts) with advanced solid tumors.

Authors: S. Piha-Paul, K. Sankhala, A. Menzies, Madhuri Dey, Julian Quiñones, Ryan T. Sowell, Prashant R. Nambiar, Robert W Shine, Katherine Kacena, S. Thomas, L. Ali, Neil Sankar, T. Kitada, J. Luke, G. V. Long

Year: 2025

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2025.43.16_suppl.9556

Paper Abstract P1-16-08: Response to subsequent therapy after dual immune checkpoint blockade in metastatic breast cancer

Shah, AN, Yalamanchili, A, Helenowski, Irene, Bhole, Sonya, Woodman, Jill, Gradishar, WJ, Cristofanilli, M, Santa-Maria, CA · 2019 · Cancer Research · DOI

Full title: Abstract P1-16-08: Response to subsequent therapy after dual immune checkpoint blockade in metastatic breast cancer

Authors: Shah, AN, Yalamanchili, A, Helenowski, Irene, Bhole, Sonya, Woodman, Jill, Gradishar, WJ, Cristofanilli, M, Santa-Maria, CA

Year: 2019

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.sabcs18-p1-16-08

Paper Companion diagnostics-a tool to improve pharmacotherapy.

Jørgensen, Jan Trøst, Hersom, Maria · 2016 · Annals of translational medicine · DOI

Full title: Companion diagnostics-a tool to improve pharmacotherapy.

Authors: Jørgensen, Jan Trøst, Hersom, Maria

Year: 2016

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm.2016.12.26

Paper Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

Hurwitz, Arthur A., Foster, Barbara A., Kwon, Eugene D., Truong, Tan, Choi, Eugene M., Greenberg, Norman M., Burg, Maurice B., Allison, James P. · 2000 · PubMed

Full title: Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

Authors: Hurwitz, Arthur A., Foster, Barbara A., Kwon, Eugene D., Truong, Tan, Choi, Eugene M., Greenberg, Norman M., Burg, Maurice B., Allison, James P.

Year: 2000

Venue: PubMed

Paper Abstract PO1-28-09: Rethinking the value of pathologic complete response rate for the survival outcomes of early triple-negative breast cancer treated with neoadjuvant chemotherapy: a systematic review and network meta-analysis

Xiaoying Qiao, Shu Wang, Taobo Hu, Baosheng Liang · 2024 · Cancer Research · DOI

Full title: Abstract PO1-28-09: Rethinking the value of pathologic complete response rate for the survival outcomes of early triple-negative breast cancer treated with neoadjuvant chemotherapy: a systematic review and network meta-analysis

Authors: Xiaoying Qiao, Shu Wang, Taobo Hu, Baosheng Liang

Year: 2024

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.sabcs23-po1-28-09

Paper Modulation of CD8+ T Cell Responses by Radiotherapy-Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors.

Jeon, Seung Hyuck, Song, Changhoon, Eom, Keun-Yong, Kim, In Ah, Kim, Jae-Sung · 2023 · International journal of molecular sciences · DOI

Full title: Modulation of CD8+ T Cell Responses by Radiotherapy-Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors.

Authors: Jeon, Seung Hyuck, Song, Changhoon, Eom, Keun-Yong, Kim, In Ah, Kim, Jae-Sung

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms242316691

Paper Combination immunotherapy: a road map.

Ott, Patrick A, Hodi, F Stephen, Kaufman, Howard L, Wigginton, Jon M, Wolchok, Jedd D · 2017 · Journal for immunotherapy of cancer · DOI

Full title: Combination immunotherapy: a road map.

Authors: Ott, Patrick A, Hodi, F Stephen, Kaufman, Howard L, Wigginton, Jon M, Wolchok, Jedd D

Year: 2017

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1186/s40425-017-0218-5

Paper Rational combinations of immunotherapy for pancreatic ductal adenocarcinoma.

Blair, Alex B, Zheng, Lei · 2017 · Chinese clinical oncology · DOI

Full title: Rational combinations of immunotherapy for pancreatic ductal adenocarcinoma.

Authors: Blair, Alex B, Zheng, Lei

Year: 2017

Venue: Chinese clinical oncology

DOI: https://doi.org/10.21037/cco.2017.06.04

Paper TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma.

Xiao, Wenjing, Du, Nan, Huang, Taoyuan, Guo, Jinan, Mo, Xingkui, Yuan, Tao, Chen, Yong, Ye, Ting, Xu, Chunwei, Wang, Wenxian, Wang, Guoqiang, Cai, Shangli, Chen, Jing · 2018 · EBioMedicine · DOI

Full title: TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma.

Authors: Xiao, Wenjing, Du, Nan, Huang, Taoyuan, Guo, Jinan, Mo, Xingkui, Yuan, Tao, Chen, Yong, Ye, Ting, Xu, Chunwei, Wang, Wenxian, Wang, Guoqiang, Cai, Shangli, Chen, Jing

Year: 2018

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2018.05.019

Thesis Peripheral T cell responses to immunotherapy treatment in metastatic melanoma

Woodcock, V · 2019 · Theses · DOI

Full title: Peripheral T cell responses to immunotherapy treatment in metastatic melanoma

Authors: Woodcock, V

Year: 2019

Venue: Theses

DOI: oai:ora.ox.ac.uk:uuid:02358ddb-9684-477c-9725-32eb469beb6d

Thesis Synergistic immuno-chemotherapy in ovarian cancer

Wahba, John · 2019 · Theses · DOI

Full title: Synergistic immuno-chemotherapy in ovarian cancer

Authors: Wahba, John

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/10044/1/75142

Thesis Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial

Reijers, Irene L M; Menzies, Alexander M; van Akkooi, Alexander C J et al. · 2022 · Theses · DOI

Full title: Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial

Authors: Reijers, Irene L M; Menzies, Alexander M; van Akkooi, Alexander C J; Versluis, Judith M; van den Heuvel, Noëlle M J; Saw, Robyn P M; Pennington, Thomas E; Kapiteijn, Ellen; van der Veldt, Astrid A M; Suijkerbuijk, Karijn P M; Hospers, Geke A P; Rozeman, Elisa A; Klop, Willem M C; van Houdt, Winan J; Sikorska, Karolina; van der Hage, Jos A; Grünhagen, Dirk J; Wouters, Michel W; Witkamp, Arjen J; Zuur, Charlotte L; Lijnsvelt, Judith M; Torres Acosta, Alejandro; Grijpink-Ongering, Lindsay G; Gonzalez, Maria; Jóźwiak, Katarzyna; Bierman, Carolien; Shannon, Kerwin F; Ch'ng, Sydney; Colebatch, Andrew J; Spillane, Andrew J; Haanen, John B A G; Rawson, Robert V; van de Wiel, Bart A; van de Poll-Franse, Lonneke V; Scolyer, Richard A; Boekhout, Annelies H; Long, Georgina V; Blank, Christian U

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/446485

Thesis Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh et al. · 2023 · Theses · DOI

Full title: Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Authors: Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh; Granhøj, Joachim Stoltenborg; Borch, Troels Holz; Peeters, Marlies J.W.; Donia, Marco; Andersen, Mads Hald; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Svane, Inge Marie; Met, Özcan; id_orcid 0000-0002-3256-7592

Year: 2023

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/dd214e21-2ea3-4190-9abd-0fde4c243316

Thesis Efficacy and safety of frontline systemic therapy for advanced HCC: a network meta-analysis of landmark phase III trials

Fulgenzi, Claudia Angela Maria; Scheiner, Bernhard; Korolewicz, James et al. · 2023 · Theses · DOI

Full title: Efficacy and safety of frontline systemic therapy for advanced HCC: a network meta-analysis of landmark phase III trials

Authors: Fulgenzi, Claudia Angela Maria; Scheiner, Bernhard; Korolewicz, James; Stikas, Charalampos-Vlasios; Gennari, Alessandra; Vincenzi, Bruno; Openshaw, Mark R; Silletta, Marianna; Pinter, Matthias; Cortellini, Alessio; Scotti, Lorenza; D'Alessio, Antonio; Pinato, David J

Year: 2023

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/37025943

Thesis Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Müller, Philipp; Kreuzaler, Matthias; Khan, Tarik et al. · 2025 · Theses · DOI

Full title: Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Authors: Müller, Philipp; Kreuzaler, Matthias; Khan, Tarik; Thommen, Daniela S; Martin, Kea; Glatz, Katharina; Savic, Spasenija; Harbeck, Nadia; Nitz, Ulrike; Gluz, Oleg; von Bergwelt-Baildon, Michael; Kreipe, Hans; Reddy, Sai; Christgen, Matthias; Zippelius, Alfred

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/33196

Thesis Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

Schmittnaegel, Martina; Rigamonti, Nicolò; Kadioglu, Ece et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

Authors: Schmittnaegel, Martina; Rigamonti, Nicolò; Kadioglu, Ece; Cassará, Antonino; Wyser Rmili, Céline; Kiialainen, Anna; Kienast, Yvonne; Mueller, Hans-Joachim; Ooi, Chia-Huey; Laoui, Damya; De Palma, Michele

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/136431

Thesis PD-1 function on T cells in spontaneous and anti-PD-1-mediated autoimmunity

Collier, Jenna Lynn · 2023 · Harvard University - DASH · DOI

Full title: PD-1 function on T cells in spontaneous and anti-PD-1-mediated autoimmunity

Authors: Collier, Jenna Lynn

Year: 2023

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37374607

Thesis Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Tardos, Elisa Catafal · 2024 · Theses · DOI

Full title: Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Authors: Tardos, Elisa Catafal

Year: 2024

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/c1afaaf9-c0a2-4ecd-9361-2f3b8d8c2788

Thesis The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)

Balermpas, Panagiotis; Rödel, Franz; Krause, Mechthild et al. · 2017 · Theses · DOI

Full title: The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)

Authors: Balermpas, Panagiotis;Rödel, Franz;Krause, Mechthild;Linge, Annett;Lohaus, Fabian;Baumann, Michael;Tinhofer, Inge;Budach, Volker;Sak, Ali;Stuschke, Martin;Gkika, Eleni;Grosu, Anca-Ligia;Abdollahi, Amir;Debus, Jürgen;Stangl, Stefan;Ganswindt, Ute;Belka, Claus;Pigorsch, Steffi;Multhoff, Gabriele;Combs, Stephanie E;Welz, Stefan;Zips, Daniel;Lim, Su Yin;Rödel, Claus;Fokas, Emmanouil

Year: 2017

Venue: Theses

DOI: https://mediatum.ub.tum.de/1427366

Thesis European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment – Update 2024

On behalf of the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC) · 2025 · Theses · DOI

Full title: European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment – Update 2024

Authors: On behalf of the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC)

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/459958

Thesis BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma

van Not, Olivier J; Blokx, Willeke A M; van den Eertwegh, Alfons J M et al. · 2022 · Theses · DOI

Full title: BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma

Authors: van Not, Olivier J; Blokx, Willeke A M; van den Eertwegh, Alfons J M; de Meza, Melissa M; Haanen, John B; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; de Groot, Jan Willem B; Hospers, Geke A P; Kapiteijn, Ellen; Piersma, Djura; van Rijn, Rozemarijn S; Stevense-den Boer, Marion; van der Veldt, Astrid A M; Boers-Sonderen, Marye J; Jansen, Anne M L; Wouters, Michel W J M; Suijkerbuijk, Karijn P M

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/447145

Thesis Computational dissection and prediction of cancer immunotherapy response

Shi, Alvin · 2022 · Theses · DOI

Full title: Computational dissection and prediction of cancer immunotherapy response

Authors: Shi, Alvin

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/1721.1/139899

Thesis Modified FOLFOX versus modified FOLFOX plus nivolumab and ipilimumab in patients with previously untreated advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction: Moonlight, a randomized phase II trial of the German Gastric Group of the AIO

Lorenzen, S.; Pauligk, C.; Goetze, T. O. et al. · 2019 · Theses · DOI

Full title: Modified FOLFOX versus modified FOLFOX plus nivolumab and ipilimumab in patients with previously untreated advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction: Moonlight, a randomized phase II trial of the German Gastric Group of the AIO

Authors: Lorenzen, S.;Pauligk, C.;Goetze, T. O.;Knorrenschild, J. Riera;Goekkurt, E.;Kullmann, F.;Pink, D.;Ettrich, T. J.;Homann, N.;Angermeier, S.;Thuss-Patience, P. C.;Lindig, U.;Bitzer, M.;Dechow, T.;Schuch, G.;Schmalenberg, H.;Junge, S.;Hofheinz, R. D.;Al-Batran, S-E.

Year: 2019

Venue: Theses

DOI: https://mediatum.ub.tum.de/1586423

Thesis Safety, Tolerability, and Potential Clinical Activity of a Glucocorticoid-Induced TNF Receptor-Related Protein Agonist Alone or in Combination with Nivolumab for Patients with Advanced Solid Tumors: A Phase 1/2a Dose-Escalation and Cohort-Expansion Clinical Trial

Heinhuis, KM; Carlino, M; Joerger, M et al. · 2025 · Theses · DOI

Full title: Safety, Tolerability, and Potential Clinical Activity of a Glucocorticoid-Induced TNF Receptor-Related Protein Agonist Alone or in Combination with Nivolumab for Patients with Advanced Solid Tumors: A Phase 1/2a Dose-Escalation and Cohort-Expansion Clinical Trial

Authors: Heinhuis, KM; Carlino, M; Joerger, M; Di, Nicola M; Meniawy, T; Rottey, S; Moreno, V; Gazzah, A; Delord, JP; Paz-Ares, L; Britschgi, C; Schilder, RJ; O'Byrne, K; Curigliano, G; Romano, E; Patah, P; Wang, R; Liu, Y; Bajaj, G; Siu, LL

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/59078

Thesis Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise et al. · 2022 · Theses · DOI

Full title: Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Authors: Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise; Khan, Shawez; Fjæstad, Klaire Yixin; Brøchner, Christian Beltoft; Linder, Hannes; Ankjærgaard, Christina; id_orcid 0000-0001-5620-6663; Donia, Marco; Chen, Inna; Nielsen, Dorte Lisbet; Behrens, Claus Preibisch; id_orcid 0000-0002-0686-1421; Madsen, Daniel Hargbøl

Year: 2022

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/7ba8c0c4-d95a-4084-9cc1-ebe6ba9f1cb6

Thesis Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Tardos, Elisa Catafal · 2024 · Theses · DOI

Full title: Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Authors: Tardos, Elisa Catafal

Year: 2024

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/c1afaaf9-c0a2-4ecd-9361-2f3b8d8c2788

Thesis Promising potential of [Lu-177]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model

Guzik, Patrycja; Siwowska, Klaudia; Fang, Hsin-Yu et al. · 2021 · Theses · DOI

Full title: Promising potential of [Lu-177]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model

Authors: Guzik, Patrycja; Siwowska, Klaudia; Fang, Hsin-Yu; Cohrs, Susan; Bernhardt, Peter; Schibli, Roger; Müller, Cristina

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/449947

Thesis NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

Ford, Kirsty; Hanley, Christopher J; Mellone, Massimiliano et al. · 2020 · Theses · DOI

Full title: NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

Authors: Ford, Kirsty; Hanley, Christopher J; Mellone, Massimiliano; Szyndralewiez, Cedric; Heitz, Freddy; Wiesel, Philippe; Wood, Oliver; Machado, Maria; Lopez, Maria-Antoinette; Ganesan, Anusha-Preethi; Wang, Chuan; Chakravarthy, Ankur; Fenton, Tim R; King, Emma V; Vijayanand, Pandurangan; Ottensmeier, Christian H; Al-Shamkhani, Aymen; Savelyeva, Natalia; Thomas, Gareth J

Year: 2020

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3095444

Thesis The immune microenvironment of ovarian cancer, as influenced by glycolysis and glutaminolysis regulation

Wang, Jingjing; 王晶晶 · 2020 · Theses · DOI

Full title: The immune microenvironment of ovarian cancer, as influenced by glycolysis and glutaminolysis regulation

Authors: Wang, Jingjing; 王晶晶

Year: 2020

Venue: Theses

DOI: https://hub.hku.hk/handle/10722/290312

Thesis Five-year review of corticosteroid duration and complications in the management of immune checkpoint inhibitor-related diarrhoea and colitis in advanced melanoma

Favara, David M; Spain, Lavinia; Au, Lewis et al. · 2021 · Theses · DOI

Full title: Five-year review of corticosteroid duration and complications in the management of immune checkpoint inhibitor-related diarrhoea and colitis in advanced melanoma

Authors: Favara, David M; Spain, Lavinia; Au, Lewis; Clark, James; Daniels, Ella; Diem, Stefan; Chauhan, Dharmisha; Turajlic, Samra; Powell, Nick; Larkin, James M; Yousaf, Nadia

Year: 2021

Venue: Theses

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000552680100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

Kverneland, Anders Handrup; Enevold, Christian; Donia, Marco et al. · 2018 · Theses · DOI

Full title: Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

Authors: Kverneland, Anders Handrup; Enevold, Christian; Donia, Marco; Bastholt, Lars; Svane, Inge Marie; Nielsen, Claus H

Year: 2018

Venue: Theses

DOI: https://researchprofiles.ku.dk/da/publications/46259398-9f9b-448c-bc62-9a861a4cd7e9

Thesis Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.

Shevtsov, Maxim; Pitkin, Emil; Ischenko, Alexander et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.

Authors: Shevtsov, Maxim;Pitkin, Emil;Ischenko, Alexander;Stangl, Stefan;Khachatryan, William;Galibin, Oleg;Edmond, Stanley;Lobinger, Dominik;Multhoff, Gabriele

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590310

Thesis Investigating multi-modal therapy with radiotherapy, vascular-targeted photodynamic therapy and immunotherapy in pre-clinical models of prostate cancer

Philippou, Y · 2021 · Theses · DOI

Full title: Investigating multi-modal therapy with radiotherapy, vascular-targeted photodynamic therapy and immunotherapy in pre-clinical models of prostate cancer

Authors: Philippou, Y

Year: 2021

Venue: Theses

DOI: oai:ora.ox.ac.uk:uuid:7eed35aa-2a70-40b1-a8c1-6695d145e195

Thesis The role of adaptive and innate immune cells in patients with colorectal cancer

Inthagard, Jitwadee · 2022 · Theses · DOI

Full title: The role of adaptive and innate immune cells in patients with colorectal cancer

Authors: Inthagard, Jitwadee

Year: 2022

Venue: Theses

DOI: https://theses.gla.ac.uk/82837/1/2021inthagardphd.pdf

Thesis Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna et al. · 2024 · Theses · DOI

Full title: Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Authors: Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna; Borch, Annie; Hendriksen, Sille; Mundt, Filip; Pedersen, Vilde; Mann, Matthias; Christensen, Ib J.; Skjøth-Ramussen, Jane; Yde, Christina W.; Kristensen, Bjarne W.; Poulsen, Hans S.; Hasselbalch, Benedikte; Svane, Inge M.; Lassen, Ulrik; Hadrup, Sine R.; id_orcid 0000-0002-5937-4344

Year: 2024

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/f4f16359-bd83-400f-9fb9-cc2e8d28b17f

Thesis Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi et al. · 2019 · Theses · DOI

Full title: Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Authors: Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi; Lee, Steve Seung-Young; Williford, John-Michael; Yasui, Mariko; Abe, Hiroyuki; Potin, Lambert; Hosseinchi, Peyman; Fukunaga, Kazuto; Raczy, Michal M.; Gray, Laura T.; Mansurov, Aslan; Katsumata, Kiyomitsu; Fukayama, Masashi; Kron, Stephen J.; Swartz, Melody A.; Hubbell, Jeffrey A.

Year: 2019

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/157854

Thesis Hyperthermic Intrathoracic Chemotherapy Modulates the Immune Microenvironment of Pleural Mesothelioma and Improves the Impact of Dual Immune Checkpoint Inhibition

Hao, Yameng; Gkasti, Aspasia; Managh, Amy J. et al. · 2025 · Theses · DOI

Full title: Hyperthermic Intrathoracic Chemotherapy Modulates the Immune Microenvironment of Pleural Mesothelioma and Improves the Impact of Dual Immune Checkpoint Inhibition

Authors: Hao, Yameng; Gkasti, Aspasia; Managh, Amy J.; Dagher, Julien; Sifis, Alexandros; Tiron, Luca; Chriqui, Louis-Emmanuel; Marie, Damien N.; Silva, Olga De Souza; Christodoulou, Michel; Peters, Solange; Joyce, Johanna A.; Krueger, Thorsten; Gonzalez, Michel; Abdelnour-Berchtold, Etienne; Sempoux, Christine; Clerc, Daniel; Teixeira-Farinha, Hugo; Hubner, Martin; Meylan, Etienne; Dyson, Paul J.; Cavin, Sabrina; Perentes, Jean Y.

Year: 2025

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/252717

Thesis Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

Priem, Bram; van Leent, Mandy M.T.; Teunissen, Abraham J.P. et al. · 2020 · Theses · DOI

Full title: Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

Authors: Priem, Bram; van Leent, Mandy M.T.; Teunissen, Abraham J.P.; Sofias, Alexandros Marios; Mourits, Vera P.; Willemsen, Lisa; Klein, Emma D.; Oosterwijk, Roderick S.; Meerwaldt, Anu E.; Munitz, Jazz; Prévot, Geoffrey; Vera Verschuur, Anna; Nauta, Sheqouia A.; van Leeuwen, Esther M.; Fisher, Elizabeth L.; de Jong, Karen A.M.; Zhao, Yiming; Toner, Yohana C.; Soultanidis, Georgios; Calcagno, Claudia; Bomans, Paul H.H.; Friedrich, Heiner; Sommerdijk, Nico; Reiner, Thomas; Duivenvoorden, Raphaël; Zupančič, Eva; Di Martino, Julie S.; Kluza, Ewelina; Rashidian, Mohammad; Ploegh, Hidde L.; Dijkhuizen, Rick M.; Hak, Sjoerd; Pérez-Medina, Carlos; Bravo-Cordero, Jose Javier; de Winther, Menno P.J.; Joosten, Leo A.B.; van Elsas, Andrea; Fayad, Zahi A.; Rialdi, Alexander; Torre, Denis; Guccione, Ernesto; Ochando, Jordi; Netea, Mihai G.; Griffioen, Arjan W.; Mulder, Willem J.M.

Year: 2020

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/441788

Thesis Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma

Schlosser, H. A.; Drebber, U.; Kloth, M. et al. · 2025 · Theses · DOI

Full title: Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma

Authors: Schlosser, H. A.; Drebber, U.; Kloth, M.; Thelen, M.; Rothschild, S. I.; Haase, S.; Garcia-Marquez, M.; Wennhold, K.; Berlth, F.; Urbanski, A.; Alakus, H.; Schauss, A.; Shimabukuro-Vornhagen, A.; Theurich, S.; Warnecke-Ebertz, U.; Stippel, D. L.; Zippelius, A.; Buttner, R.; Hallek, M.; Holscher, A. H.; Zander, T.; Monig, S. P.; von Bergwelt-Baildon, M.

Year: 2025

Venue: Theses

DOI: http://hdl.handle.net/20.500.14716/33737

Thesis IN RESPONSE: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A cohort study

van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Dekkers, Olaf M et al. · 2021 · Theses · DOI

Full title: IN RESPONSE: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A cohort study

Authors: van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Dekkers, Olaf M; Kapiteijn, Ellen

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/443705

Thesis Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

Hooper, Andrea T.; Marquette, Kimberly; Chang, Chao-Pei Betty et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

Authors: Hooper, Andrea T.; Marquette, Kimberly; Chang, Chao-Pei Betty; Golas, Jonathon; Jain, Sadhana; Lam, My-Hanh; Guffroy, Magali; Leal, Mauricio; Falahatpisheh, Hadi; Mathur, Divya; Chen, Ting; Kelleher, Kerry; Khandke, Kiran; Muszynska, Elwira; Loganzo, Frank; Rosfjord, Edward; Lucas, Judy; Kan, Zhengyan; Subramanyam, Chakrapani; O'Donnell, Christopher; Neri, Dario; id_orcid0000-0001-5234-7370; Gerber, Hans-Peter; May, Chad; Sapra, Puja

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/570266

Thesis Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma

Rossi, Niccolo; Lee, Karla A; Bermudez, Maria V et al. · 2022 · Theses · DOI

Full title: Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma

Authors: Rossi, Niccolo; Lee, Karla A; Bermudez, Maria V; Visconti, Alessia; Thomas, Andrew Maltez; Bolte, Laura A; Bjork, Johannes R; Ruijter, Laura Kist de; Newton-Bishop, Julia; Harland, Mark; Shaw, Heather M; Harries, Mark; Sacco, Joseph; Board, Ruth; Lorigan, Paul; Vries, Elisabeth GE de; Segata, Nicola; Taams, Leonie; Papa, Sophie; Spector, Tim D; Nathan, Paul; Weersma, Rinse K; Hospers, Geke AP; Fehrmann, Rudolf SN; Bataille, Veronique; Falchi, Mario

Year: 2022

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3167852

Thesis Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Klepsch, V; Hermann-Kleiter, N; Do-Dinh, P et al. · 2025 · Theses · DOI

Full title: Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Authors: Klepsch, V; Hermann-Kleiter, N; Do-Dinh, P; Jakic, B; Offermann, A; Efremova, M; Sopper, S; Rieder, D; Krogsdam, A; Gamerith, G; Perner, S; Tzankov, A; Trajanoski, Z; Wolf, D; Baier, G

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/39136

Thesis Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako et al. · 2020 · Theses · DOI

Full title: Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Authors: Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako; Larsson, Hans M; Potin, Lambert; Hosseinchi, Peyman; Galliverti, Gabriele; Swartz, Melody A; Hubbell, Jeffrey A

Year: 2020

Venue: Theses

DOI: https://stm.sciencemag.org/content/9/415/eaan0401

Thesis Metabolic regulation of CD8 T cell functions in the tumor microenvironment

Qiu, Jing · 2017 · Theses · DOI

Full title: Metabolic regulation of CD8 T cell functions in the tumor microenvironment

Authors: Qiu, Jing

Year: 2017

Venue: Theses

DOI: https://openscholarship.wustl.edu/art_sci_etds/1141

Thesis Hyperthermic intrathoracic chemotherapy to control malignant pleural mesothelioma

Hao, Yameng · 2023 · Theses · DOI

Full title: Hyperthermic intrathoracic chemotherapy to control malignant pleural mesothelioma

Authors: Hao, Yameng

Year: 2023

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/197168

Thesis Systematic review with meta-analysis: effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced enterocolitis

Ibraheim, Hair; Powell, Nicholas · 2020 · Theses · DOI

Full title: Systematic review with meta-analysis: effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced enterocolitis

Authors: Ibraheim, Hair; Powell, Nicholas

Year: 2020

Venue: Theses

DOI: https://onlinelibrary.wiley.com/doi/full/10.1111/apt.15998

Thesis Antitumor activity of IL-2 and IL-7 immunocomplexes in combination with αCTLA-4 and αPD-1 mAbs

Hnízdilová, Tereza · 2019 · Theses · DOI

Full title: Antitumor activity of IL-2 and IL-7 immunocomplexes in combination with αCTLA-4 and αPD-1 mAbs

Authors: Hnízdilová, Tereza

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/20.500.11956/109938

Thesis The Systemic Treatment of Melanoma

Terheyden, Patrick; Krackhardt, Angela; Eigentler, Thomas · 2019 · Theses · DOI

Full title: The Systemic Treatment of Melanoma

Authors: Terheyden, Patrick;Krackhardt, Angela;Eigentler, Thomas

Year: 2019

Venue: Theses

DOI: https://mediatum.ub.tum.de/1589630

Thesis Persistent Cancer Cells Alter Interferon Signaling After Immune Checkpoint Blockade

Ye, Darwin · 2024 · Theses · DOI

Full title: Persistent Cancer Cells Alter Interferon Signaling After Immune Checkpoint Blockade

Authors: Ye, Darwin

Year: 2024

Venue: Theses

DOI: https://repository.upenn.edu/handle/20.500.14332/59529

Thesis High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

Eranki, Avinash; Srinivasan, Priya; Ries, Mario et al. · 2020 · Theses · DOI

Full title: High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

Authors: Eranki, Avinash; Srinivasan, Priya; Ries, Mario; Kim, AeRang; Lazarski, Christopher A; Rossi, Christopher T; Khokhlova, Tatiana D; Wilson, Emmanuel; Knoblach, Susan M; Sharma, Karun V; Wood, Bradford J; Moonen, Chrit; Sandler, Anthony D; Kim, Peter C W

Year: 2020

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/394637

Thesis Improved survival with ipilimumab in patients with metastatic melanoma

Hodi, FS; O'Day, SJ; McDermott, DF et al. · 2010 · Theses · DOI

Full title: Improved survival with ipilimumab in patients with metastatic melanoma

Authors: Hodi, FS;O'Day, SJ;McDermott, DF;Weber, RW;Sosman, JA;Haanen, JB;Gonzalez, R;Robert, C;Schadendorf, D;Hassel, JC;Akerley, W;van den Eertwegh, AJ;Lutzky, J;Lorigan, P;Vaubel, JM;Linette, GP;Hogg, D;Ottensmeier, CH;Lebbe, C;Peschel, C;Quirt, I;Clark, JI;Wolchok, JD;Weber, JS;Tian, J;Yellin, MJ;Nichol, GM;Hoos, A;Urba, WJ

Year: 2010

Venue: Theses

DOI: https://mediatum.ub.tum.de/1077761

Thesis [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]

Miller, Kurt; Bergmann, Lothar; Doehn, Christian et al. · 2019 · Theses · DOI

Full title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]

Authors: Miller, Kurt;Bergmann, Lothar;Doehn, Christian;Gschwend, Jürgen E;Kuczyk, Markus A

Year: 2019

Venue: Theses

DOI: https://mediatum.ub.tum.de/1591191

Thesis Intravital imaging of adoptive T-Cell morphology, mobility and trafficking following immune checkpoint inhibition in a mouse melanoma model

Lau, Doreen; Garcon, Fabien; Chandra, Anita et al. · 2020 · Imperial College London · DOI

Full title: Intravital imaging of adoptive T-Cell morphology, mobility and trafficking following immune checkpoint inhibition in a mouse melanoma model

Authors: Lau, Doreen; Garcon, Fabien; Chandra, Anita; Lechermann, Laura M; Aloj, Luigi; Chilvers, Edwin R; Corrie, Pippa G; Okkenhaug, Klaus; Gallagher, Ferdia A

Year: 2020

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000559343800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Predictors of responses to immune checkpoint blockade in advanced melanoma

Jacquelot, N; Roberti, M P; Enot, D P et al. · 2017 · Theses · DOI

Full title: Predictors of responses to immune checkpoint blockade in advanced melanoma

Authors: Jacquelot, N; Roberti, M P; Enot, D P; Rusakiewicz, S; Ternès, N; Jegou, S; Woods, D M; Sodré, A L; Hansen, M; Meirow, Y; Sade-Feldman, M; Burra, A; Kwek, S S; Flament, C; Messaoudene, M; Duong, C P M; Chen, L; Kwon, B S; Anderson, A C; Kuchroo, V K; Weide, B; Aubin, F; Borg, C; Dalle, S; Beatrix, O; Ayyoub, M; Balme, B; Tomasic, G; Di Giacomo, A M; Maio, M; Schadendorf, D; Melero, I; Dréno, B; Khammari, A; Dummer, R; Levesque, M; Koguchi, Y; Fong, L; Lotem, M; Baniyash, M; Schmidt, H; Svane, I M; Kroemer, G; Marabelle, A; Michiels, S; Cavalcanti, A; Smyth, M J; Weber, J S; Eggermont, A M; Zitvogel, L

Year: 2017

Venue: Theses

DOI: https://researchprofiles.ku.dk/da/publications/5e126806-9328-4dd2-8faf-9ef61a088635

Thesis The role of CKLF-Like MARVEL transmembrane domain-containing 4 in tumour immunology of liver cancer

Chui, Nog Qin Noreen; 徐諾芊 · 2021 · Theses · DOI

Full title: The role of CKLF-Like MARVEL transmembrane domain-containing 4 in tumour immunology of liver cancer

Authors: Chui, Nog Qin Noreen; 徐諾芊

Year: 2021

Venue: Theses

DOI: https://hub.hku.hk/handle/10722/300432

Thesis Determinants Of Adaptive Immunity In Cancer

Rech, Andrew J · 2023 · Theses · DOI

Full title: Determinants Of Adaptive Immunity In Cancer

Authors: Rech, Andrew J

Year: 2023

Venue: Theses

DOI: https://repository.upenn.edu/handle/20.500.14332/29472

Thesis Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

Nanda, VGY; Peng, W; Hwu, P et al. · 2020 · Theses · DOI

Full title: Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

Authors: Nanda, VGY; Peng, W; Hwu, P; Davies, MA; Ciliberto, G; Fattore, L; Malpicci, D; Aurisicchio, L; Ascierto, PA; Croce, CM; Mancini, R; Spranger, S; Gajewski, TF; Wang, Y; Ferrone, S; Vanpouille-Box, C; Wennerberg, E; Pilones, KA; Formenti, SC; Demaria, S; Tang, H; Wang, Y; Fu, Y-X; Dummer, R; Puzanov, I; Tarhini, A; Chauvin, J-M; Pagliano, O; Fourcade, J; Sun, Z; Wang, H; Sanders, C; Kirkwood, JM; Chen, T-HT; Maurer, M; Korman, AJ; Zarour, HM; Stroncek, DF; Huber, V; Rivoltini, L; Thurin, M; Rau, T; Lugli, A; Pagès, F; Camarero, J; Sancho, A; Jommi, C; de Coaña, YP; Wolodarski, M; Yoshimoto, Y; Gentilcore, G; Poschke, I; Masucci, GV; Hansson, J; Kiessling, R; Scognamiglio, G; Sabbatino, F; Marino, FZ; Anniciello, AM; Cantile, M; Cerrone, M; Scala, S; D’alterio, C; Ianaro, A; Cirin, G; Liguori, G; Bott, G; Chapman, PB; Robert, C; Larkin, J; Haanen, JB; Ribas, A; Hogg, D; Hamid, O; Testori, A; Lorigan, P; Sosman, JA; Flaherty, KT; Yue, H; Coleman, S; Caro, I; Hauschild, A; McArthur, GA; Sznol, M; Callahan, MK; Kluger, H; Postow, MA; Gordan, R; Segal, NH; Rizvi, NA; Lesokhin, A; Atkins, MB; Burke, MM; Ralabate, A; Rivera, A; Kronenberg, SA; Agunwamba, B; Ruisi, M; Horak, C; Jiang, J; Wolchok, J; Ascierto, PA; Liszkay, G; Maio, M; Mandalà, M; Demidov, L; Stoyakovskiy, D; Thomas, L; de la Cruz-Merino, L; Atkinson, V; Dutriaux, C; Garbe, C; Wongchenko, M; Chang, I; Koralek, DO; Rooney, I; Yan, Y; Dréno, B; Sullivan, R; Patel, M; Hodi, S; Amaria, R; Boasberg, P; Wallin, J; He, X; Cha, E; Richie, N; Ballinger, M; Smith, DC; Bauer, TM; Wasser, JS; Luke, JJ; Balmanoukian, AS; Kaufman, DR; Zhao, Y; Maleski, J; Leopold, L; Gangadhar, TC; Long, GV; Michielin, O; VanderWalde, A; Andtbacka, RHI; Cebon, J; Fernandez, E; Malvehy, J; Olszanski, AJ; Gause, C; Chen, L; Chou, J; Stephen Hodi, F; Brady, B; Mortier, L; Hassel, JC; Rutkowski, P; McNeil, C; Kalinka-Warzocha, E; Lebbé, C; Ny, L; Chacon, M; Queirolo, P; Loquai, C; Cheema, P; Berrocal, A; Eizmendi, KM; Bar-Sela, G; Horak, C; Hardy, H; Weber, JS; Grob, J-J; Marquez-Rodas, I; Schmidt, H; Briscoe, K; Baurain, J-F; Wolchok, JD; Pinto, R; De Summa, S; Garrisi, VM; Strippoli, S; Azzariti, A; Guida, G; Guida, M; Tommasi, S; Jacquelot, N; Enot, D; Flament, C; Pitt, JM; Vimond, N; Blattner, C; Yamazaki, T; Roberti, M-P; Vetizou, M; Daillere, R; Poirier-Colame, V; la Semeraro, M; Caignard, A; Slingluff, CL; Sallusto, F; Rusakiewicz, S; Weide, B; Marabelle, A; Kohrt, H; Dalle, S; Cavalcanti, A; Kroemer, G; Di Giacomo, AM; Maio, M; Wong, P; Yuan, J; Umansky, V; Eggermont, A; Zitvogel, L; Anna, P; Marco, T; Stefania, S; Francesco, M; Mariaelena, C; Gabriele, M; Antonio, AP; Franco, S; Roberti, MP; Enot, DP; Semeraro, M; Jégou, S; Flores, C; Chen, T-HT; Kwon, BS; Anderson, AC; Borg, C; Aubin, F; Ayyoub, M; De Presbiteris, AL; Cordaro, FG; Camerlingo, R; Fratangelo, F; Mozzillo, N; Pirozzi, G; Patriarca, EJ; Caputo, E; Motti, ML; Falcon, R; Miceli, R; Capone, M; Madonna, G; Mallardo, D; Carrier, MV; Panza, E; De Cicco, P; Armogida, C; Ercolano, G; Botti, G; Cirino, G; Sandru, A; Blank, M; Balatoni, T; Olasz, J; Farkas, E; Szollar, A; Savolt, A; Godeny, M; Csuka, O; Horvath, S; Eles, K; Shoenfeld, Y; Kasler, M; Costantini, S; Capone, F; Moradi, F; Berglund, P; Leandersson, K; Linnskog, R; Andersson, T; Prasad, CP; Nigro, CL; Lattanzio, L; Wang, H; Proby, C; Syed, N; Occelli, M; Cauchi, C; Merlano, M; Harwood, C; Thompson, A; Crook, T; Bifulco, K; Ingangi, V; Minopoli, M; Ragone, C; Pessi, A; Mannavola, F; D’Oronzo, S; Felici, C; Tucci, M; Doronzo, A; Silvestris, F; Ferretta, A; Guida, S; Maida, I; Cocco, T; Passarelli, A; Quaresmini, D; Franzese, O; Palermo, B; Di Donna, C; Sperduti, I; Foddai, M; Stabile, H; Gismondi, A; Santoni, A; Nisticò, P; Sponghini, AP; Platini, F; Marra, E; Rondonotti, D; Alabiso, O; Fierro, MT; Savoia, P; Stratica, F; Quaglino, P; Di Monta, G; Corrado, C; Di Marzo, M; Ugo, M; Di Cecilia, ML; Nicola, M; Fusciello, C; Marra, A; Guarrasi, R; Baldi, C; Russo, R; Di Giulio, G; Faiola, V; Zeppa, P; Pepe, S; Gambale, E; Carella, C; Di Paolo, A; De Tursi, M; Marra, L; De Murtas, F; Sorrentino, V; Voinea, S; Panaitescu, E; Bolovan, M; Stanciu, A; Cinca, S; Botti, C; Aquino, G; Anniciello, A; Fortes, C; Mastroeni, S; Caggiati, A; Passarelli, F; Zappalà, A; Capuano, M; Bono, R; Nudo, M; Marino, C; Michelozzi, P; De Biasio, V; Battarra, VC; Formenti, S; Ascierto, ML; McMiller, TL; Berger, AE; Danilova, L; Anders, RA; Netto, GJ; Xu, H; Pritchard, TS; Fan, J; Cheadle, C; Cope, L; Drake, CG; Pardoll, DM; Taube, JM; Topalian, SL; Gnjatic, S; Nataraj, S; Imai, N; Rahman, A; Jungbluth, AA; Pan, L; Venhaus, R; Park, A; Lehmann, FF; Lendvai, N; Cohen, AD; Cho, HJ; Daniel, S; Hirsh, V

Year: 2020

Venue: Theses

DOI: https://hdl.handle.net/11343/256123

Thesis Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Triggers Global Microglia Activation

Yang, Yuanfan · 2022 · Theses · DOI

Full title: Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Triggers Global Microglia Activation

Authors: Yang, Yuanfan

Year: 2022

Venue: Theses

DOI: https://hdl.handle.net/10161/25748

Thesis Botensilimab, an Fc-enhanced anti-CTLA-4 antibody, is effective against tumors poorly responsive to conventional immunotherapy

Chand, Dhan; Savitsky, David A; Krishnan, Shanmugarajan et al. · 2024 · Theses · DOI

Full title: Botensilimab, an Fc-enhanced anti-CTLA-4 antibody, is effective against tumors poorly responsive to conventional immunotherapy

Authors: Chand, Dhan; Savitsky, David A; Krishnan, Shanmugarajan; Mednick, Gabriel; Delepine, Chloe; Garcia-Broncano, Pilar; Soh, Kah Teong; Wu, Wei; Wilkens, Margaret K; Udartseva, Olga; Vincent, Sylvia; Joshi, Bishnu; Keith, Justin G; Manrique, Mariana; Marques, Marilyn; Tanne, Antoine; Levey, Daniel L; Han, Haiyong; Ng, Serina; Ridpath, Jackson; Huber, Olivia; Morin, Benjamin; Galand, Claire; Bourdelais, Sean; Gombos, Randi B; Ward, Rebecca; Qin, Yu; Waight, Jeremy D; Costa, Matthew R; Sebastian-Yague, Alvaro; Rudqvist, Nils-Petter; Pupecka-Swider, Malgorzata; Venkatraman, Vignesh; Slee, Andrew; Patel, Jaymin M; Grossman, Joseph E; Wilson, Nicholas S; Von Hoff, Daniel D; Stebbing, Justin; Curiel, Tyler J; Buell, Jennifer S; O'Day, Steven J; Stein, Robert B

Year: 2024

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/39083809

Thesis FDG PET in the evaluation of immune-related hypophysitis and thyroiditis following combination ipilimumab and nivolumab in advanced melanoma

Iravani, A; Galligan, A; Lasocki, A et al. · 2024 · Theses · DOI

Full title: FDG PET in the evaluation of immune-related hypophysitis and thyroiditis following combination ipilimumab and nivolumab in advanced melanoma

Authors: Iravani, A; Galligan, A; Lasocki, A; Wallace, R; Weppler, A; Yeung, GA; Akhurst, T; Sachithanandan, N; Chiang, C; Sandhu, S; Hicks, R

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/345609

Thesis Biomarkers of response and resistance to anti-PD1 immunotherapy in melanoma

Gide, Tuba Nur · 2019 · Theses · DOI

Full title: Biomarkers of response and resistance to anti-PD1 immunotherapy in melanoma

Authors: Gide, Tuba Nur

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/2123/21200

Thesis Temozolomide and Anti-PD1 Immunotherapy in Glioblastoma Treatment: Insights from the GL261-luc2 Mouse Model

Dhar, Zara · 2025 · Theses · DOI

Full title: Temozolomide and Anti-PD1 Immunotherapy in Glioblastoma Treatment: Insights from the GL261-luc2 Mouse Model

Authors: Dhar, Zara

Year: 2025

Venue: Theses

DOI: https://escholarship.org/uc/item/8zb3r3cp

Thesis Cross-reactivity and functionality of approved human immune checkpoint blockers in dogs

Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Ranninger, Elisabeth et al. · 2021 · Theses · DOI

Full title: Cross-reactivity and functionality of approved human immune checkpoint blockers in dogs

Authors: Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Ranninger, Elisabeth; https://orcid.org/0000-0002-4345-5203; Guerrera, Diego; https://orcid.org/0000-0002-5323-4447; Hutter, Gregor; Maake, Caroline; https://orcid.org/0000-0003-0378-8203; Markkanen, Enni; https://orcid.org/0000-0001-7780-8233; Bettschart-Wolfensberger, Regula; https://orcid.org/0000-0001-6259-9678; Rohrer Bley, Carla; https://orcid.org/0000-0002-5733-2722; Läubli, Heinz; https://orcid.org/0000-0002-8910-5620; vom Berg, Johannes; https://orcid.org/0000-0002-4086-1564

Year: 2021

Venue: Theses

DOI: oai:www.zora.uzh.ch:20.500.14742/181371

Thesis **Authors:** Keenan, Bridget P. **Institution:** Johns Hopkins University **Date:** 2015-09-16T03:38:14Z

Keenan, Bridget P. · 2015 · Theses · DOI

Full title: **Authors:** Keenan, Bridget P. **Institution:** Johns Hopkins University **Date:** 2015-09-16T03:38:14Z

Authors: Keenan, Bridget P.

Year: 2015

Venue: Theses

DOI: http://jhir.library.jhu.edu/handle/1774.2/37977

Thesis Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako et al. · 2017 · Theses · DOI

Full title: Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Authors: Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako; Larsson, Hans M.; Potin, Lambert; Hosseinchi, Peyman; Galliverti, Gabriele; Swartz, Melody A.; Hubbell, Jeffrey A.

Year: 2017

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/142581

Thesis A targetable type III immune response with increase of IL-17A expressing CD4⁺T cells is associated with immunotherapy-induced toxicity in melanoma

Dimitriou, Florentia; Cheng, Phil F.; Saltari, Annalisa et al. · 2024 · Theses · DOI

Full title: A targetable type III immune response with increase of IL-17A expressing CD4⁺T cells is associated with immunotherapy-induced toxicity in melanoma

Authors: Dimitriou, Florentia; Cheng, Phil F.; Saltari, Annalisa; Schaper-Gerhardt, Katrin; Staeger, Ramon; Haunerdinger, Veronika; Sella, Federica; Tastanova, Aizhan; Urban, Christian; Dettwiler, Susanne; Mihic-Probst, Daniela; Matter, Christian M.; Michielin, Olivier; Gutzmer, Ralf; Long, Georgina V.; Becher, Burkhard; Levesque, Mitchell P.; Dummer, Reinhard

Year: 2024

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/694328

Thesis First-line treatment options for PD-L1-negative non-small cell lung cancer: a Bayesian network meta-analysis

Peng, Ling; Liang, Wen-Hua; Mu, De-Guang et al. · 2021 · Theses · DOI

Full title: First-line treatment options for PD-L1-negative non-small cell lung cancer: a Bayesian network meta-analysis

Authors: Peng, Ling; Liang, Wen-Hua; Mu, De-Guang; Xu, Song; Hong, Shao-Dong; Stebbing, Justin; Liang, Fei; Xia, Yang

Year: 2021

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/34249693

Thesis PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer

Goh, Pei Kee (Monash University / Peter MacCallum Cancer Centre); McLean, Catriona (Alfred Hospital); Zeissig, Mara N. (Monash University / Peter MacCallum Cancer Centre) et al. · 2022 · Theses · DOI

Full title: PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer

Authors: Goh, Pei Kee (Monash University / Peter MacCallum Cancer Centre); McLean, Catriona (Alfred Hospital); Zeissig, Mara N. (Monash University / Peter MacCallum Cancer Centre); Wiede, Florian (Monash University / Peter MacCallum Cancer Centre); Tiganis, Tony (Monash University / Peter MacCallum Cancer Centre); Humbert, Patrick O. (University of Melbourne / La Trobe University); Müller, Mathias (University of Veterinary Medicine Vienna); Loi, Sherene (Peter MacCallum Cancer Centre / University of Melbourne); Xu, Rachel (Monash University / Peter MacCallum Cancer Centre); Goode, Nathan (La Trobe University); Molloy, Tim (St. Vincent's Centre for Applied Medical Research); Britt, Kara L. (Peter MacCallum Cancer Centre / The University of Melbourne)

Year: 2022

Venue: Theses

DOI: https://phaidra.vetmeduni.ac.at/o:1787

Thesis Tumor intrinsic pathways dictate the immune landscape and responses to immune checkpoint inhibitors in liver cancer

Yuen, Wai Hin; 袁瑋軒 · 2023 · Theses · DOI

Full title: Tumor intrinsic pathways dictate the immune landscape and responses to immune checkpoint inhibitors in liver cancer

Authors: Yuen, Wai Hin; 袁瑋軒

Year: 2023

Venue: Theses

DOI: https://hub.hku.hk/handle/10722/328606

Thesis Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus et al. · 2020 · Theses · DOI

Full title: Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Authors: Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus; Hasselager, Thomas; Olsen, Lars Rønn; id_orcid 0000-0002-6725-7850; Anglesio, Michael S.; Borch, Troels Holz; Kennedy, Mia; Briggs, Gillian; Ledoux, Stacey; Kreuzinger, Caroline; von der Decken, Isabel; Donia, Marco; Castillo-Tong, Dan Cacsire; Nelson, Brad H.; Svane, Inge Marie

Year: 2020

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/904a44aa-c867-4721-a512-23240a1e06e3

Thesis Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel et al. · 2016 · Theses · DOI

Full title: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Authors: McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel; Andersen, Sofie Ramskov; Lyngaa, Rikke Birgitte; Saini, Sunil Kumar; id_orcid 0000-0003-3382-9432; Jamal-Hanjani, Mariam; Wilson, Gareth A; Birkbak, Nicolai J.; Hiley, Crispin T; Watkins, Thomas B K; Shafi, Seema; Murugaesu, Nirupa; Mitter, Richard; Akarca, Ayse U; Linares, Joseph; Marafioti, Teresa; Henry, Jake Y; Van Allen, Eliezer M; Miao, Diana; Schilling, Bastian; Schadendorf, Dirk; Garraway, Levi A; Makarov, Vladimir; Rizvi, Naiyer A; Snyder, Alexandra; Hellmann, Matthew D; Merghoub, Taha; Wolchok, Jedd D; Shukla, Sachet A; Wu, Catherine J; Peggs, Karl S; Chan, Timothy A; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Quezada, Sergio A; Swanton, Charles

Year: 2016

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/c36e3271-a3d9-46b6-b0d1-d3537ae20249

Thesis **Authors:** Mishra, Akhilesh **Institution:** Johns Hopkins University **Date:** 2024-05-30T16:58:18Z

Mishra, Akhilesh · 2024 · Theses · DOI

Full title: **Authors:** Mishra, Akhilesh **Institution:** Johns Hopkins University **Date:** 2024-05-30T16:58:18Z

Authors: Mishra, Akhilesh

Year: 2024

Venue: Theses

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/69539

Thesis Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

Zimmer, Lisa; Apuri, Susmitha; Eroglu, Zeynep et al. · 2017 · Theses · DOI

Full title: Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

Authors: Zimmer, Lisa;Apuri, Susmitha;Eroglu, Zeynep;Kottschade, Lisa A;Forschner, Andrea;Gutzmer, Ralf;Schlaak, Max;Heinzerling, Lucie;Krackhardt, Angela M;Loquai, Carmen;Markovic, Svetomir N;Joseph, Richard W;Markey, Kelly;Utikal, Jochen S;Weishaupt, Carsten;Goldinger, Simone M;Sondak, Vernon K;Zager, Jonathan S;Schadendorf, Dirk;Khushalani, Nikhil I

Year: 2017

Venue: Theses

DOI: https://mediatum.ub.tum.de/1439987

Thesis Efficacy and safety of novel immune checkpoint inhibitor-based combinations versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer: A network meta-analysis

Yang, C; Xuan, T; Gong, Q et al. · 2024 · Theses · DOI

Full title: Efficacy and safety of novel immune checkpoint inhibitor-based combinations versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer: A network meta-analysis

Authors: Yang, C; Xuan, T; Gong, Q; Dai, X; Wang, C; Zhang, R; Zhao, W; Wang, J; Yue, W; Li, J

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/351235

Thesis Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma

Vermeulen, Jeroen F.; Van Hecke, Wim; Adriaansen, Elisabeth J M et al. · 2018 · Theses · DOI

Full title: Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma

Authors: Vermeulen, Jeroen F.; Van Hecke, Wim; Adriaansen, Elisabeth J M; Jansen, Mieke K.; Bouma, Rianne G.; Villacorta Hidalgo, José; Fisch, Paul; Broekhuizen, Roel; Spliet, Wim G.M.; Kool, Marcel; Bovenschen, Niels

Year: 2018

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/363746

Thesis Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M et al. · 2024 · Theses · DOI

Full title: Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Authors: Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M; Keller, Kaylee M; Barisa, Marta; Poon, Evon; Munnings-Tomes, Sophie; Himsworth, Courtney; Calton, Elizabeth; Rodriguez, Ana; Bernardi, Ronald; van den Ham, Femke; van Hooff, Sander R; Matser, Yvette A H; Tas, Michelle L; Langenberg, Karin P S; Lijnzaad, Philip; Borst, Anne L; Zappa, Elisa; Bergsma, Francisca J; Strijker, Josephine G M; Verhoeven, Bronte M; Mei, Shenglin; Kramdi, Amira; Restuadi, Restuadi; Sanchez-Bernabeu, Alvaro; Cornel, Annelisa M; Holstege, Frank C P; Gray, Juliet C; Tytgat, Godelieve A M; Scheijde-Vermeulen, Marijn A; Wijnen, Marc H W A; Dierselhuis, Miranda P; Straathof, Karin; Behjati, Sam; Wu, Wei; Heck, Albert J R; Koster, Jan; Nierkens, Stefan; Janoueix-Lerosey, Isabelle; de Krijger, Ronald R; Baryawno, Ninib; Chesler, Louis; Anderson, John; Caron, Hubert N; Margaritis, Thanasis; van Noesel, Max M; Molenaar, Jan J

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/451805

Thesis Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells

Amaro, Adriana; Reggiani, Francesco; Fenoglio, Daniela et al. · 2023 · Theses · DOI

Full title: Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells

Authors: Amaro, Adriana; Reggiani, Francesco; Fenoglio, Daniela; Gangemi, Rosaria; Tosi, Anna; Parodi, Alessia; Banelli, Barbara; Rigo, Valentina; Mastracci, Luca; Grillo, Federica; Cereghetti, Alessandra; Tastanova, Aizhan; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Sallustio, Fabio; Emionite, Laura; Daga, Antonio; Altosole, Tiziana; Filaci, Gilberto; Rosato, Antonio; Levesque, Mitchell; Maio, Michele; Pfeffer, Ulrich; EPigenetic Immune-oncology Consortium Airc (EPICA) consortium

Year: 2023

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/606158

Thesis Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Zhou, Xiuman; Du, Jiangfeng; Wang, Hongfei et al. · 2020 · Theses · DOI

Full title: Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Authors: Zhou, Xiuman; Du, Jiangfeng; Wang, Hongfei; Chen, Chunxia; Jiao, Ling; Cheng, Xiangrui; Zhou, Xiaowen; Chen, Shaomeng; Gou, Shanshan; Zhao, Wenshan; Zhai, Wenjie; Chen, Junhui; Gao, Yanfeng

Year: 2020

Venue: Theses

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-106151

Thesis Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease

Diem, S; Hasan, Ali O; Ackermann, CJ et al. · 2025 · Theses · DOI

Full title: Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease

Authors: Diem, S; Hasan, Ali O; Ackermann, CJ; Bomze, D; Koelzer, VH; Jochum, W; Speiser, DE; Mertz, KD; Flatz, L

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/34782

Thesis Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A Cohort Study

van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Aarts, Maureen J B et al. · 2021 · Theses · DOI

Full title: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A Cohort Study

Authors: van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; van Breeschoten, Jesper; van den Eertwegh, Alfonsus J M; B de Groot, Jan Willem; Haanen, John B A G; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; van Zeijl, Michiel C T; Wouters, Michel W J M; Dekkers, Olaf M; Kapiteijn, Ellen

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/442298

Thesis Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

Cousin, Nikola; Cap, Stefan; Dihr, Manuel et al. · 2021 · Theses · DOI

Full title: Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

Authors: Cousin, Nikola; Cap, Stefan; Dihr, Manuel; Tacconi, Carlotta; Detmar, Michael; Dieterich, Lothar C.

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/500391

Thesis Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced antitumor T-cell responses

Beavis, PA; Milenkovski, N; Henderson, MA et al. · 2017 · Theses · DOI

Full title: Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced antitumor T-cell responses

Authors: Beavis, PA; Milenkovski, N; Henderson, MA; John, LB; Allard, B; Loi, S; Kershaw, MH; Stagg, J; Darcy, PK

Year: 2017

Venue: Theses

DOI: https://hdl.handle.net/11343/190464

Thesis Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Nava Rodrigues, Daniel; Alimonti, Andrea; id_orcid0000-0002-9362-2313 et al. · 2018 · Theses · DOI

Full title: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Authors: Nava Rodrigues, Daniel; Alimonti, Andrea; id_orcid0000-0002-9362-2313; et al.

Year: 2018

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/657225

Thesis [Advanced bladder cancer : From chemo- to immunotherapy]

Horn, T; Krege, S; Retz, M · 2018 · Theses · DOI

Full title: [Advanced bladder cancer : From chemo- to immunotherapy]

Authors: Horn, T;Krege, S;Retz, M

Year: 2018

Venue: Theses

DOI: https://mediatum.ub.tum.de/1586464

Thesis Efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient advanced pancreatic adenocarcinoma: an AGEO European Cohort

Taïeb, Julien; Sayah, Lina; Heinrich, Kathrin et al. · 2023 · Theses · DOI

Full title: Efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient advanced pancreatic adenocarcinoma: an AGEO European Cohort

Authors: Taïeb, Julien; Sayah, Lina; Heinrich, Kathrin; Kunzmann, Volker; Boileve, Alice; Cirkel, Geert; Lonardi, Sara; Chibaudel, Benoist; Turpin, Anthony; Beller, Tamar; Hautefeuille, Vincent; Vivaldi, Caterina; Mazard, Thibault; Bauguion, Lucile; Niger, Monica; Prager, Gerald W.; Coutzac, Clelia; Benedikt Westphalen, C.; Auclin, Edouard; Pilla, Lorenzo

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/459180

Thesis RIG-I activation is critical for responsiveness to checkpoint blockade

Heidegger, Simon; Wintges, Alexander; Stritzke, Florian et al. · 2019 · Theses · DOI

Full title: RIG-I activation is critical for responsiveness to checkpoint blockade

Authors: Heidegger, Simon;Wintges, Alexander;Stritzke, Florian;Bek, Sarah;Steiger, Katja;Koenig, Paul-Albert;Göttert, Sascha;Engleitner, Thomas;Öllinger, Rupert;Nedelko, Tatiana;Fischer, Julius C;Makarov, Vladimir;Winter, Christof;Rad, Roland;van den Brink, Marcel R M;Ruland, Jürgen;Bassermann, Florian;Chan, Timothy A;Haas, Tobias;Poeck, Hendrik

Year: 2019

Venue: Theses

DOI: https://mediatum.ub.tum.de/1589747

Thesis Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna et al. · 2024 · Theses · DOI

Full title: Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Year: 2024

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/f4f16359-bd83-400f-9fb9-cc2e8d28b17f

Thesis Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben et al. · 2021 · Theses · DOI

Full title: Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Authors: Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben; Rohrberg, Kristoffer; Reker Hadrup, Sine; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2021

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/a2066594-9c4f-4789-98cd-954e4dedb11a

Thesis Modulating Innate Immunity via CD40-based Myeloid Targeting can Overcome anti-PD1 Therapy Resistance

Krykbaeva, Irina · 2022 · Theses · DOI

Full title: Modulating Innate Immunity via CD40-based Myeloid Targeting can Overcome anti-PD1 Therapy Resistance

Authors: Krykbaeva, Irina

Year: 2022

Venue: Theses

DOI: https://elischolar.library.yale.edu/gsas_dissertations/615

Thesis Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus et al. · 2020 · Theses · DOI

Full title: Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Year: 2020

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/904a44aa-c867-4721-a512-23240a1e06e3

Thesis The role of hypoxia on myeloid-derived suppressor cell accumulation in hepatocellular carcinoma

Chiu, Kung-chun; 趙公雋 · 2018 · University of Hong Kong · DOI

Full title: The role of hypoxia on myeloid-derived suppressor cell accumulation in hepatocellular carcinoma

Authors: Chiu, Kung-chun; 趙公雋

Year: 2018

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/261492

Thesis ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer

Sonpavde, Guru; Necchi, Andrea; Gupta, Shilpa et al. · 2020 · Theses · DOI

Full title: ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer

Authors: Sonpavde, Guru;Necchi, Andrea;Gupta, Shilpa;Steinberg, Gary D;Gschwend, Juergen E;Van Der Heijden, Michiel Simon;Garzon, Nathalie;Ibrahim, Mohammed;Raybold, Bradley;Liaw, Danny;Rutstein, Mark;Galsky, Matt D

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1617192

Thesis Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted

Kraehenbuehl, Lukas; Winkelbeiner, Nicola; Turko, Patrick et al. · 2025 · Theses · DOI

Full title: Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted

Authors: Kraehenbuehl, Lukas; Winkelbeiner, Nicola; Turko, Patrick; Staeger, Ramon; Ghosh, Adhideb; Kaiser, Vivienn; Stadler, Pia-Charlotte; Nordmann, Thierry M.; Brüggen, Marie-Charlotte; Levesque, Mitchell P.; Contassot, Emmanuel; French, Lars E.; Dummer, Reinhard; Meier-Schiesser, Barbara

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/201773

Thesis Nivolumab with or without Ipilimumab Combined with Stereotactic Body Radiotherapy in Patients with Metastatic Biliary Tract Cancer:A Randomized Phase 2 Study

Markussen, Alice; Johansen, Julia S.; Larsen, Finn O. et al. · 2024 · Theses · DOI

Full title: Nivolumab with or without Ipilimumab Combined with Stereotactic Body Radiotherapy in Patients with Metastatic Biliary Tract Cancer:A Randomized Phase 2 Study

Authors: Markussen, Alice; Johansen, Julia S.; Larsen, Finn O.; Theile, Susann; Hasselby, Jane P.; Willemoe, Gro L.; Lorentzen, Torben; Madsen, Kasper; Høgdall, Estrid; Poulsen, Tim S.; Wilken, Eva E.; Geertsen, Poul; Behrens, Claus P.; id_orcid 0000-0002-0686-1421; Svane, Inge M.; Nielsen, Dorte; Chen, Inna M.

Year: 2024

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/3cf3ae48-2b4c-4503-b2c3-fb9d710f25c4

Thesis Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius et al. · 2023 · Theses · DOI

Full title: Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Authors: Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius; Østrup, Olga; Yde, Christina Westmose; Eklund, Aron Charles; Mau-Sørensen, Morten; Barra, Carolina; id_orcid 0000-0002-6836-4906; Svane, Inge Marie; Nielsen, Finn Cilius; Funt, Samuel A.; Lassen, Ulrik; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344

Year: 2023

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/6f236ce4-64f3-4b8e-931d-050ca22e0acc

Thesis Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB-IVM1c melanoma

Malvehy, Josep; Samoylenko, Igor; Schadendorf, Dirk et al. · 2021 · Theses · DOI

Full title: Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB-IVM1c melanoma

Authors: Malvehy, Josep; Samoylenko, Igor; Schadendorf, Dirk; Gutzmer, Ralf; Grob, Jean-Jacques; Sacco, Joseph J; Gorski, Kevin S; Anderson, Abraham; Pickett, Cheryl A; Liu, Kate; Gogas, Helen

Year: 2021

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3120757

Thesis Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors

Silva, Ana P. S.; Coelho, Priscila V.; Anazetti, Maristella et al. · 2018 · Theses · DOI

Full title: Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors

Authors: Silva, Ana P. S.; Coelho, Priscila V.; Anazetti, Maristella; Simioni, Patricia U. [UNESP]

Year: 2018

Venue: Theses

DOI: http://dx.doi.org/10.1080/21645515.2016.1249551

Thesis Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI

Zakaria, Rasheed; Jenkinson, Michael D; Radon, Mark et al. · 2023 · Theses · DOI

Full title: Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI

Authors: Zakaria, Rasheed; Jenkinson, Michael D; Radon, Mark; Das, Kumar; Poptani, Harish; Rathi, Nitika; Rudland, Philip S

Year: 2023

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3171844

Thesis Immune checkpoint inhibitor–associated sarcoidosis: A usually benign disease that does not require immunotherapy discontinuation

ICIR; Coordination; Co-Convenors et al. · 2021 · Theses · DOI

Full title: Immune checkpoint inhibitor–associated sarcoidosis: A usually benign disease that does not require immunotherapy discontinuation

Authors: ICIR; Coordination; Co-Convenors; Steering committee; Research Fellows; Data Scientist

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/444450

Thesis The role of macrophages in the host response to radiation

Jones, K · 2018 · University of Oxford - ORA · DOI

Full title: The role of macrophages in the host response to radiation

Authors: Jones, K

Year: 2018

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:34a90de7-05cf-4008-8f1d-0596af71a5bc

Thesis Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer

Li, R; Sant, S; Brown, E et al. · 2023 · Theses · DOI

Full title: Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer

Authors: Li, R; Sant, S; Brown, E; Caramia, F; Nikolic, B; Clarke, K; Byrne, A; Lara Gonzalez, LE; Savas, P; Luen, SJ; Teo, ZL; Virassamy, B; Neeson, PJ; Darcy, PK; Loi, S

Year: 2023

Venue: Theses

DOI: https://hdl.handle.net/11343/338908

Thesis Induction of T Cell Immunity Overcomes Resistance to Pd-1 and Ctla-4 Blockade and Improves Survival in Pancreatic Cancer

Winograd, Rafael · 2023 · Theses · DOI

Full title: Induction of T Cell Immunity Overcomes Resistance to Pd-1 and Ctla-4 Blockade and Improves Survival in Pancreatic Cancer

Authors: Winograd, Rafael

Year: 2023

Venue: Theses

DOI: https://repository.upenn.edu/handle/20.500.14332/27947

Thesis Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients

Amaral, Teresa; Kiecker, Felix; Schaefer, Sarah et al. · 2020 · Theses · DOI

Full title: Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients

Authors: Amaral, Teresa;Kiecker, Felix;Schaefer, Sarah;Stege, Henner;Kaehler, Katharina;Terheyden, Patrick;Gesierich, Anja;Gutzmer, Ralf;Haferkamp, Sebastian;Uttikal, Jochen;Berking, Carola;Rafei-Shamsabadi, David;Reinhardt, Lydia;Meier, Friedegund;Karoglan, Ante;Posch, Christian;Gambichler, Thilo;Pfoehler, Claudia;Thoms, Kai;Tietze, Julia;Debus, Dirk;Herbst, Rudolf;Emmert, Steffen;Loquai, Carmen;Hassel, Jessica C;Meiss, Frank;Tueting, Thomas;Heinrich, Vanessa;Eigentler, Thomas;Garbe, Claus;Zimmer, Lisa

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1618364

Thesis Differential Regulation of miRNAs During Anti-PD-1 Therapy Modulates Tumor Immune Infiltration

Deng, Yufei · 2024 · Theses · DOI

Full title: Differential Regulation of miRNAs During Anti-PD-1 Therapy Modulates Tumor Immune Infiltration

Authors: Deng, Yufei

Year: 2024

Venue: Theses

DOI: https://escholarship.org/uc/item/8dz0w84g

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke et al. · 2017 · Theses · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke; Rosenkrantz, Lisbet Holmich; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/25caf41f-8965-4658-b672-f62d5d7ff1d3

Thesis Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217)

Tintelnot, Joseph; Goekkurt, Eray; Binder, Mascha et al. · 2020 · Theses · DOI

Full title: Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217)

Authors: Tintelnot, Joseph;Goekkurt, Eray;Binder, Mascha;Thuss-Patience, Peter;Lorenzen, Sylvie;Knorrenschild, Jorge Riera;Kretzschmar, Albrecht;Ettrich, Thomas;Lindig, Udo;Jacobasch, Lutz;Pink, Daniel;Al-Batran, Salah-Eddin;Hinke, Axel;Hegewisch-Becker, Susanna;Nilsson, Sven;Bokemeyer, Carsten;Stein, Alexander

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1588790

Thesis Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus

Toberer, Ferdinand; Winkler, Julia K.; Atienza Fernandez, Leroy et al. · 2025 · Theses · DOI

Full title: Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus

Authors: Toberer, Ferdinand; Winkler, Julia K.; Atienza Fernandez, Leroy; Adams, Lea; Brobeil, Alexander; Tóth, Marcell; Enk, Alexander H.; Becker, Jürgen C.; Lonsdorf, Anke S.

Year: 2025

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/745322

Thesis [The role of immunooncology in the treatment of urothelial cancer]

Retz, Margitta; Tauber, Robert; Horn, Thomas · 2017 · Theses · DOI

Full title: [The role of immunooncology in the treatment of urothelial cancer]

Authors: Retz, Margitta;Tauber, Robert;Horn, Thomas

Year: 2017

Venue: Theses

DOI: https://mediatum.ub.tum.de/1445624

Thesis Nivolumab with or without ipilimumab in patients with recurrent or metastatic cervical cancer (CheckMate 358): a phase 1-2, open-label, multicohort trial

Oaknin, Ana; Moore, Kathleen; Meyer, Tim et al. · 2024 · Theses · DOI

Full title: Nivolumab with or without ipilimumab in patients with recurrent or metastatic cervical cancer (CheckMate 358): a phase 1-2, open-label, multicohort trial

Authors: Oaknin, Ana; Moore, Kathleen; Meyer, Tim; López-Picazo González, José; Devriese, Lot A; Amin, Asim; Lao, Christopher D; Boni, Valentina; Sharfman, William H; Park, Jong Chul; Tahara, Makoto; Topalian, Suzanne L; Magallanes, Manuel; Molina Alavez, Alejandro; Khan, Tariq Aziz; Copigneaux, Catherine; Lee, Michelle; Garnett-Benson, Charlie; Wang, Xuya; Naumann, R Wendel

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/452541

Thesis Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC)

von Witzleben, Adrian; Fehn, Adrian; Grages, Ayla et al. · 2021 · Theses · DOI

Full title: Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC)

Authors: von Witzleben, Adrian; Fehn, Adrian; Grages, Ayla; Ezic, Jasmin; Jeske, Sandra S; Puntigam, Lisa K; Brunner, Cornelia; Kraus, Johann M; Kestler, Hans A; Doescher, Johannes; Brand, Matthias; Theodoraki, Marie-Nicole; Ottensmeier, Christian H; Hoffmann, Thomas K; Schuler, Patrick J; Laban, Simon

Year: 2021

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3129388

Thesis OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors

Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M et al. · 2021 · Theses · DOI

Full title: OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors

Authors: Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M; Olszanski, Anthony J; Spreafico, Anna; Ong, Michael; Chu, Quincy S; Carvajal, Richard D; Trigo, José; Ochoa de Olza, Maria; Provencio, Mariano; De Vos, Filip; de Braud, Filippo; Leong, Stephen; Lathers, Deanne; Wang, Rui; Ravindran, Palani; Feng, Yan; Aanur, Praveen; Melero, Ignacio

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/440999

Thesis Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

de Lima, Vinicius Araujo B.; Borch, Annie; Hansen, Morten et al. · 2020 · Theses · DOI

Full title: Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

Authors: de Lima, Vinicius Araujo B.; Borch, Annie; Hansen, Morten; Draghi, Arianna; Spanggaard, Iben; Rohrberg, Kristoffer; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2020

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/09aacc10-7dff-4078-947b-c2af24b266f4

Thesis Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Eschweiler, Simon; Clarke, James; Ramirez-Suastegui, Ciro et al. · 2021 · Theses · DOI

Full title: Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Authors: Eschweiler, Simon; Clarke, James; Ramirez-Suastegui, Ciro; Panwar, Bharat; Madrigal, Ariel; Chee, Serena J; Karydis, Ioannis; Woo, Edwin; Alzetani, Aiman; Elsheikh, Somaia; Hanley, CJ; Thomas, GJ; Friedmann, Peter S; Sanchez-Elsner, Tilman; Ay, Ferhat; Ottensmeier, Christian H; Vijayanand, Pandurangan

Year: 2021

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3145789

Thesis Mechanisms of Acquired Resistance to Immune Therapies in Lung Cancer

Robles-Oteiza, Camila · 2021 · Theses · DOI

Full title: Mechanisms of Acquired Resistance to Immune Therapies in Lung Cancer

Authors: Robles-Oteiza, Camila

Year: 2021

Venue: Theses

DOI: https://elischolar.library.yale.edu/gsas_dissertations/400

Thesis Development of plant-produced bispecific monoclonal antibody targeting PD-L1 and CTLA-4 for cancer immunotherapy

Isip Bulaon, Christine Joy · 2022 · Theses · DOI

Full title: Development of plant-produced bispecific monoclonal antibody targeting PD-L1 and CTLA-4 for cancer immunotherapy

Authors: Isip Bulaon, Christine Joy

Year: 2022

Venue: Theses

DOI: https://digital.car.chula.ac.th/chulaetd/10360

Thesis The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021 · Theses · DOI

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Year: 2021

Venue: Theses

DOI: oai:livrepository.liverpool.ac.uk:3145804

Thesis SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, A; Iravani, A; Lasocki, A et al. · 2024 · Theses · DOI

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, A; Iravani, A; Lasocki, A; Wallace, R; Weppler, A; Au-Yeung, G; Sachithanandan, N; Chiang, CY; Wentworth, J; Colman, PG; Kay, TW; Krishnamurthy, B; Sandhu, S

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/345607

Thesis Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

Jensen, Christina; Madsen, Daniel Hargbøl; Hansen, Morten et al. · 2018 · Theses · DOI

Full title: Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

Authors: Jensen, Christina; Madsen, Daniel Hargbøl; Hansen, Morten; Schmidt, Henrik; Svane, Inge Marie; Karsdal, Morten Asser; Willumsen, Nicholas

Year: 2018

Venue: Theses

DOI: https://researchprofiles.ku.dk/da/publications/bc5c7559-c561-4036-b9f5-f6807d3400c1

Thesis Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi et al. · 2020 · Theses · DOI

Full title: Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Authors: Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi; Lee, Steve Seung-Young; Williford, John-Michael; Yasui, Mariko; Abe, Hiroyuki; Potin, Lambert; Hosseinchi, Peyman; Fukunaga, Kazuto; Raczy, Michal M; Gray, Laura T; Mansurov, Aslan; Katsumata, Kiyomitsu; Fukayama, Masashi; Kron, Stephen J; Swartz, Melody A; Hubbell, Jeffrey A

Year: 2020

Venue: Theses

DOI: https://stm.sciencemag.org/content/11/487/eaau3259/tab-pdf

Thesis Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma

Theurich, S.; Rothschild, S. I.; Hoffmann, M. et al. · 2025 · Theses · DOI

Full title: Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma

Authors: Theurich, S.; Rothschild, S. I.; Hoffmann, M.; Fabri, M.; Sommer, A.; Garcia-Marquez, M.; Thelen, M.; Schill, C.; Merki, R.; Schmid, T.; Koeberle, D.; Zippelius, A.; Baues, C.; Mauch, C.; Tigges, C.; Kreuter, A.; Borggrefe, J.; von Bergwelt-Baildon, M.; Schlaak, M.

Year: 2025

Venue: Theses

DOI: http://hdl.handle.net/20.500.14716/33958

Thesis Model-based optimization of cancer immunotherapy combinations

Sánchez Fernández, Javier · 2025 · Theses · DOI

Full title: Model-based optimization of cancer immunotherapy combinations

Authors: Sánchez Fernández, Javier

Year: 2025

Venue: Theses

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-544014

Thesis Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Natoli, Marina; Bonito, Nair; Robinson, James D et al. · 2020 · Theses · DOI

Full title: Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Authors: Natoli, Marina; Bonito, Nair; Robinson, James D; Ghaem-Maghami, Sadaf; Mao, Yumeng

Year: 2020

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/32200422

Thesis Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands

van Zeijl, Michiel C T; van Breeschoten, Jesper; de Wreede, Liesbeth C et al. · 2023 · Theses · DOI

Full title: Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands

Authors: van Zeijl, Michiel C T; van Breeschoten, Jesper; de Wreede, Liesbeth C; Wouters, Michel W J M; Hilarius, Doranne L; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; de Groot, Jan Willem B; Hospers, Geke A P; Kapiteijn, Ellen; Piersma, Djura; van Rijn, Rozemarijn S; Stevense-den Boer, Marion A; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Boers-Sonderen, Marye J; Suijkerbuijk, Karijn P M; Haanen, John B A G; van den Eertwegh, Alfons J M

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/449093

Thesis Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel et al. · 2016 · Theses · DOI

Full title: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Year: 2016

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/c36e3271-a3d9-46b6-b0d1-d3537ae20249

Thesis Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

Celis-Gutierrez, Javier; Blattmann, Peter; id_orcid0000-0001-9105-6381 et al. · 2019 · Theses · DOI

Full title: Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

Authors: Celis-Gutierrez, Javier; Blattmann, Peter; id_orcid0000-0001-9105-6381; Zhai, Yunhao; Jarmuzynski, Nicolas; Ruminski, Kilian; Grégoire, Claude; Ounoughene, Youcef; Fiore, Frédéric; Aebersold, Ruedi; Roncagalli, Romain; Gstaiger, Matthias; Malissen, Bernard

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/348044

Thesis Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius et al. · 2023 · Theses · DOI

Full title: Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Year: 2023

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/6f236ce4-64f3-4b8e-931d-050ca22e0acc

Thesis [Interdisciplinary recommendations for the treatment of advanced metastatic renal cell carcinoma]

Miller, Kurt; Bergmann, Lothar; Doehn, Christian et al. · 2020 · Theses · DOI

Full title: [Interdisciplinary recommendations for the treatment of advanced metastatic renal cell carcinoma]

Authors: Miller, Kurt;Bergmann, Lothar;Doehn, Christian;Grünwald, Viktor;Gschwend, Jürgen E;Ivanyi, Philipp;Keilholz, Ulrich;Kuczyk, Markus A

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1617366

Thesis Repositioning azelnidipine as a dual inhibitor targeting cd47/sirpα and tigit/pvr pathways for cancer immuno-therapy

Zhou, Xiuman; Jiao, Ling; Qian, Yuzhen et al. · 2021 · Theses · DOI

Full title: Repositioning azelnidipine as a dual inhibitor targeting cd47/sirpα and tigit/pvr pathways for cancer immuno-therapy

Authors: Zhou, Xiuman; Jiao, Ling; Qian, Yuzhen; Dong, Qingyu; Sun, Yixuan; Zheng, Wei V.; Zhao, Weishan; Zhai, Weijie; Qiu, Lu; Wu, Yahong; Wang, Hongfei; Gao, Yanfeng; Chen, Junhui

Year: 2021

Venue: Theses

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-110873

Thesis Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma

Meng, Yuzhong · 2019 · Theses · DOI

Full title: Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma

Authors: Meng, Yuzhong

Year: 2019

Venue: Theses

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42013164

Thesis Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

Weber, Jeffrey S; D'Angelo, Sandra P; Minor, David et al. · 2015 · Theses · DOI

Full title: Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

Authors: Weber, Jeffrey S;D'Angelo, Sandra P;Minor, David;Hodi, F Stephen;Gutzmer, Ralf;Neyns, Bart;Hoeller, Christoph;Khushalani, Nikhil I;Miller, Wilson H;Lao, Christopher D;Linette, Gerald P;Thomas, Luc;Lorigan, Paul;Grossmann, Kenneth F;Hassel, Jessica C;Maio, Michele;Sznol, Mario;Ascierto, Paolo A;Mohr, Peter;Chmielowski, Bartosz;Bryce, Alan;Svane, Inge M;Grob, Jean-Jacques;Krackhardt, Angela M;Horak, Christine;Lambert, Alexandre;Yang, Arvin S;Larkin, James

Year: 2015

Venue: Theses

DOI: https://mediatum.ub.tum.de/1321975

Thesis Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma

Blank, Christian U; Lucas, Minke W; Scolyer, Richard A et al. · 2024 · Theses · DOI

Full title: Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma

Authors: Blank, Christian U; Lucas, Minke W; Scolyer, Richard A; van de Wiel, Bart A; Menzies, Alexander M; Lopez-Yurda, Marta; Hoeijmakers, Lotte L; Saw, Robyn P M; Lijnsvelt, Judith M; Maher, Nigel G; Pulleman, Saskia M; Gonzalez, Maria; Torres Acosta, Alejandro; van Houdt, Winan J; Lo, Serigne N; Kuijpers, Anke M J; Spillane, Andrew; Klop, W Martin C; Pennington, Thomas E; Zuur, Charlotte L; Shannon, Kerwin F; Seinstra, Beatrijs A; Rawson, Robert V; Haanen, John B A G; Ch'ng, Sydney; Naipal, Kishan A T; Stretch, Jonathan; van Thienen, Johannes V; Rtshiladze, Michael A; Wilgenhof, Sofie; Kapoor, Rony; Meerveld-Eggink, Aafke; Grijpink-Ongering, Lindsay G; van Akkooi, Alexander C J; Reijers, Irene L M; Gyorki, David E; Grünhagen, Dirk J; Speetjens, Frank M; Vliek, Sonja B; Placzke, Joanna; Spain, Lavinia; Stassen, Robert C; Amini-Adle, Mona; Lebbé, Céleste; Faries, Mark B; Robert, Caroline; Ascierto, Paolo A; van Rijn, Rozemarijn; van den Berkmortel, Franchette W P J; Piersma, Djura; van der Westhuizen, Andre; Vreugdenhil, Gerard; Aarts, Maureen J B; Stevense-den Boer, Marion A M; Atkinson, Victoria; Khattak, Muhammad; Andrews, Miles C; van den Eertwegh, Alfons J M; Boers-Sonderen, Marye J; Hospers, Geke A P; Carlino, Matteo S; de Groot, Jan-Willem B; Kapiteijn, Ellen; Suijkerbuijk, Karijn P M; Rutkowski, Piotr; Sandhu, Shahneen; van der Veldt, Astrid A M; Long, Georgina V

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/457935

Thesis First-in-Human Study of the Biodistribution and Pharmacokinetics of Zr-89-CX-072, a Novel Immunopet Tracer Based on an Anti-PD-L1 Probody

Kist de Ruijter, Laura; Hooiveld-Noeken, Jahlisa S; Giesen, Danique et al. · 2021 · Theses · DOI

Full title: First-in-Human Study of the Biodistribution and Pharmacokinetics of Zr-89-CX-072, a Novel Immunopet Tracer Based on an Anti-PD-L1 Probody

Authors: Kist de Ruijter, Laura; Hooiveld-Noeken, Jahlisa S; Giesen, Danique; Lub-de Hooge, Marjolijn N; Kok, Iris C; Brouwers, Adrienne H; Elias, Sjoerd G; Nguyen, Margaret T L; Lu, Hong; Gietema, Jourik A; Jalving, Mathilde; de Groot, Derk J A; Vasiljeva, Olga; de Vries, Elisabeth G E

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/445262

Thesis PKC ? Germline Variants and Genetic Deletion in Mice Augment Anti-Tumor Immunity Through Regulation of Myeloid Cells

Cron, Kyle Ryan · 2022 · Theses · DOI

Full title: PKC ? Germline Variants and Genetic Deletion in Mice Augment Anti-Tumor Immunity Through Regulation of Myeloid Cells

Authors: Cron, Kyle Ryan

Year: 2022

Venue: Theses

DOI: https://knowledge.uchicago.edu/record/4882/files/Table%20S5.xlsx

Thesis Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh et al. · 2023 · Theses · DOI

Full title: Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Year: 2023

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/dd214e21-2ea3-4190-9abd-0fde4c243316

Thesis Current systemic treatment of metastatic bladder cancer

Horn, T.; von Amsberg, G.; Tauber, R. et al. · 2018 · Theses · DOI

Full title: Current systemic treatment of metastatic bladder cancer

Authors: Horn, T.;von Amsberg, G.;Tauber, R.;Retz, M.

Year: 2018

Venue: Theses

DOI: https://mediatum.ub.tum.de/1587016

Thesis Programmed cell death ligands expression drives immune tolerogenesis across the diverse subtypes of neuroendocrine tumours

Pinato, David J; Vallipuram, Anu; Evans, Joanne S et al. · 2020 · Theses · DOI

Full title: Programmed cell death ligands expression drives immune tolerogenesis across the diverse subtypes of neuroendocrine tumours

Authors: Pinato, David J; Vallipuram, Anu; Evans, Joanne S; Wong, Clement; Zhang, Hua; Brown, Matthew; Dina, Roberto E; Trivedi, Pritesh; Akarca, Ayse U; Marafioti, Teresa; Mauri, Francesco A; Sharma, Rohini

Year: 2020

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/32097935

Thesis Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on the IL23/IFNg axis

Lo, J; Cozzetto, D; Madgwick, M et al. · 2023 · Theses · DOI

Full title: Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on the IL23/IFNg axis

Authors: Lo, J; Cozzetto, D; Madgwick, M; Sieh, JYXS; Olbei, M; Alexander, JL; Blanco, J Miguens; Kudo, H; Ibraheim, H; Liu, Z; Seoane, R Castro; Goldin, R; Marchesi, J; Korcsmaros, T; Lord, G; Powell, N

Year: 2023

Venue: Theses

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000778573400132&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Molecular homology between canine spontaneous oral squamous cell carcinomas and human head-and-neck squamous cell carcinomas reveals disease drivers and therapeutic vulnerabilities

Guscetti, Franco; https://orcid.org/0000-0002-3173-4811; Nassiri, Sina et al. · 2020 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Molecular homology between canine spontaneous oral squamous cell carcinomas and human head-and-neck squamous cell carcinomas reveals disease drivers and therapeutic vulnerabilities

Authors: Guscetti, Franco; https://orcid.org/0000-0002-3173-4811; Nassiri, Sina; Beebe, Erin; Rito Brandao, Inês; Graf, Ramona; Markkanen, Enni; https://orcid.org/0000-0001-7780-8233

Year: 2020

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/174159

Thesis T cells in HBV associated hepatocellular carcinoma and other cancers

Li, X · 2017 · Theses · DOI

Full title: T cells in HBV associated hepatocellular carcinoma and other cancers

Authors: Li, X

Year: 2017

Venue: Theses

DOI: oai:ora.ox.ac.uk:uuid:bb17db80-554e-453c-8daa-c550fea30cc2

Thesis Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

Rohaan, Maartje W; Borch, Troels H; van den Berg, Joost H et al. · 2022 · Theses · DOI

Full title: Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

Authors: Rohaan, Maartje W; Borch, Troels H; van den Berg, Joost H; Met, Özcan; Kessels, Rob; Geukes Foppen, Marnix H; Stoltenborg Granhøj, Joachim; Nuijen, Bastiaan; Nijenhuis, Cynthia; Jedema, Inge; van Zon, Maaike; Scheij, Saskia; Beijnen, Jos H; Hansen, Marten; Voermans, Carlijn; Noringriis, Inge M; Monberg, Tine J; Holmstroem, Rikke B; Wever, Lidwina D V; van Dijk, Marloes; Grijpink-Ongering, Lindsay G; Valkenet, Ludy H M; Torres Acosta, Alejandro; Karger, Matthias; Borgers, Jessica S W; Ten Ham, Renske M T; Retèl, Valesca P; van Harten, Wim H; Lalezari, Ferry; van Tinteren, Harm; van der Veldt, Astrid A M; Hospers, Geke A P; Stevense-den Boer, Marion A M; Suijkerbuijk, Karijn P M; Aarts, Maureen J B; Piersma, Djura; van den Eertwegh, Alfons J M; de Groot, Jan-Willem B; Vreugdenhil, Gerard; Kapiteijn, Ellen; Boers-Sonderen, Marye J; Fiets, W Edward; van den Berkmortel, Franchette W P J; Ellebaek, Eva; Hölmich, Lisbet R; van Akkooi, Alexander C J; van Houdt, Winan J; Wouters, Michel W J M; van Thienen, Johannes V; Blank, Christian U; Meerveld-Eggink, Aafke; Klobuch, Sebastian; Wilgenhof, Sofie; Schumacher, Ton N; Donia, Marco; Svane, Inge Marie; Haanen, John B A G

Year: 2022

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/447886

Thesis The use of immunotherapy in solid tumours : efficacy and toxicity

Wong, Sum-lung; 黃心龍 · 2018 · Theses · DOI

Full title: The use of immunotherapy in solid tumours : efficacy and toxicity

Authors: Wong, Sum-lung; 黃心龍

Year: 2018

Venue: Theses

DOI: https://hub.hku.hk/handle/10722/252496

Thesis Melanoma and immunotherapy bridge 2015: Naples, Italy. 1-5 December 2015

Nanda, Vashisht GY; Peng, Weiyi; Hwu, Patrick et al. · 2024 · Theses · DOI

Full title: Melanoma and immunotherapy bridge 2015: Naples, Italy. 1-5 December 2015

Authors: Nanda, Vashisht GY; Peng, Weiyi; Hwu, Patrick; Davies, Michael A; Ciliberto, Gennaro; Fattore, Luigi; Malpicci, Debora; Aurisicchio, Luigi; Ascierto, Paolo Antonio; Croce, Carlo M; Mancini, Rita; Spranger, Stefani; Gajewski, Thomas F; Wang, Yangyang; Ferrone, Soldano; Vanpouille-Box, Claire; Wennerberg, Erik; Pilones, Karsten A; Formenti, Silvia C; Demaria, Sandra; Tang, Haidong; Wang, Yang; Fu, Yang-Xin; Dummer, Reinhard; Puzanov, Igor; Tarhini, Ahmad; Chauvin, Joe-Marc; Pagliano, Ornella; Fourcade, Julien; Sun, Zhaojun; Wang, Hong; Sanders, Cindy; Kirkwood, John M; Chen, Tseng-hui Timothy; Maurer, Mark; Korman, Alan J; Zarour, Hassane M; Stroncek, David F; Huber, Veronica; Rivoltini, Licia; Thurin, Magdalena; Rau, Tilman; Lugli, Alessandro; Pagès, Franck; Camarero, Jorge; Sancho, Arantxa; Jommi, Claudio; de Coaña, Yago Pico; Wolodarski, Maria; Yoshimoto, Yuya; Gentilcore, Giusy; Poschke, Isabel; Masucci, Giuseppe V; Hansson, Johan; Kiessling, Rolf; Scognamiglio, Giosuè; Sabbatino, Francesco; Marino, Federica Zito; Anniciello, Anna Maria; Cantile, Monica; Cerrone, Margherita; Scala, Stefania; D’alterio, Crescenzo; Ianaro, Angela; Cirin, Giuseppe; Liguori, Giuseppina; Bott, Gerardo; Chapman, Paul B; Robert, Caroline; Larkin, James; Haanen, John B; Ribas, Antoni; Hogg, David; Hamid, Omid; Testori, Alessandro; Lorigan, Paul; Sosman, Jeffrey A; Flaherty, Keith T; Yue, Huibin; Coleman, Shelley; Caro, Ivor; Hauschild, Axel; McArthur, Grant A; Sznol, Mario; Callahan, Margaret K; Kluger, Harriet; Postow, Michael A; Gordan, RuthAnn; Segal, Neil H; Rizvi, Naiyer A; Lesokhin, Alexander; Atkins, Michael B; Burke, Matthew M; Ralabate, Amanda; Rivera, Angel; Kronenberg, Stephanie A; Agunwamba, Blessing; Ruisi, Mary; Horak, Christine; Jiang, Joel; Wolchok, Jedd; Ascierto, Paolo A; Liszkay, Gabriella; Maio, Michele; Mandalà, Mario; Demidov, Lev; Stoyakovskiy, Daniil; Thomas, Luc; de la Cruz-Merino, Luis; Atkinson, Victoria; Dutriaux, Caroline; Garbe, Claus; Wongchenko, Matthew; Chang, Ilsung; Koralek, Daniel O; Rooney, Isabelle; Yan, Yibing; Dréno, Brigitte; Sullivan, Ryan; Patel, Manish; Hodi, Stephen; Amaria, Rodabe; Boasberg, Peter; Wallin, Jeffrey; He, Xian; Cha, Edward; Richie, Nicole; Ballinger, Marcus; Smith, David C; Bauer, Todd M; Wasser, Jeffrey S; Luke, Jason J; Balmanoukian, Ani S; Kaufman, David R; Zhao, Yufan; Maleski, Janet; Leopold, Lance; Gangadhar, Tara C; Long, Georgina V; Michielin, Olivier; VanderWalde, Ari; Andtbacka, Robert HI; Cebon, Jonathan; Fernandez, Eugenio; Malvehy, Josep; Olszanski, Anthony J; Gause, Christine; Chen, Lisa; Chou, Jeffrey; Stephen Hodi, F; Brady, Benjamin; Mortier, Laurent; Hassel, Jessica C; Rutkowski, Piotr; McNeil, Catriona; Kalinka-Warzocha, Ewa; Lebbé, Celeste; Ny, Lars; Chacon, Matias; Queirolo, Paola; Loquai, Carmen; Cheema, Parneet; Berrocal, Alfonso; Eizmendi, Karmele Mujika; Bar-Sela, Gil; Horak, Christine; Hardy, Helene; Weber, Jeffrey S; Grob, Jean-Jacques; Marquez-Rodas, Ivan; Schmidt, Henrik; Briscoe, Karen; Baurain, Jean-François; Wolchok, Jedd D; Pinto, Rosamaria; De Summa, Simona; Garrisi, Vito Michele; Strippoli, Sabino; Azzariti, Amalia; Guida, Gabriella; Guida, Michele; Tommasi, Stefania; Jacquelot, Nicolas; Enot, David; Flament, Caroline; Pitt, Jonathan M; Vimond, Nadège; Blattner, Carolin; Yamazaki, Takahiro; Roberti, Maria-Paula; Vetizou, Marie; Daillere, Romain; Poirier-Colame, Vichnou; la Semeraro, Michaë; Caignard, Anne; Slingluff, Craig L; Sallusto, Federica; Rusakiewicz, Sylvie; Weide, Benjamin; Marabelle, Aurélien; Kohrt, Holbrook; Dalle, Stéphane; Cavalcanti, Andréa; Kroemer, Guido; Di Giacomo, Anna Maria; Maio, Michaele; Wong, Phillip; Yuan, Jianda; Umansky, Viktor; Eggermont, Alexander; Zitvogel, Laurence; Anna, Passarelli; Marco, Tucci; Stefania, Stucci; Francesco, Mannavola; Mariaelena, Capone; Gabriele, Madonna; Antonio, Ascierto Paolo; Franco, Silvestris; Roberti, María Paula; Enot, David P; Semeraro, Michaela; Jégou, Sarah; Flores, Camila; Chen, Tseng-hui Timothy; Kwon, Byoung S; Anderson, Ana Carrizossa; Borg, Christophe; Aubin, François; Ayyoub, Maha; De Presbiteris, Anna Lisa; Cordaro, Fabiola Gilda; Camerlingo, Rosa; Fratangelo, Federica; Mozzillo, Nicola; Pirozzi, Giuseppe; Patriarca, Eduardo J; Caputo, Emilia; Motti, Maria Letizia; Falcon, Rosaria; Miceli, Roberta; Capone, Mariaelena; Madonna, Gabriele; Mallardo, Domenico; Carrier, Maria Vincenza; Panza, Elisabetta; De Cicco, Paola; Armogida, Chiara; Ercolano, Giuseppe; Botti, Gerardo; Cirino, Giuseppe; Sandru, Angela; Blank, Miri; Balatoni, Timea; Olasz, Judit; Farkas, Emil; Szollar, Andras; Savolt, Akos; Godeny, Maria; Csuka, Orsolya; Horvath, Szabolcs; Eles, Klara; Shoenfeld, Yehuda; Kasler, Miklos; Costantini, Susan; Capone, Francesca; Moradi, Farnaz; Berglund, Pontus; Leandersson, Karin; Linnskog, Rickard; Andersson, Tommy; Prasad, Chandra Prakash; Nigro, Cristiana Lo; Lattanzio, Laura; Wang, Hexiao; Proby, Charlotte; Syed, Nelofer; Occelli, Marcella; Cauchi, Carolina; Merlano, Marco; Harwood, Catherine; Thompson, Alastair; Crook, Tim; Bifulco, Katia; Ingangi, Vincenzo; Minopoli, Michele; Ragone, Concetta; Pessi, Antonello; Mannavola, Francesco; D’Oronzo, Stella; Felici, Claudia; Tucci, Marco; Doronzo, Antonio; Silvestris, Franco; Ferretta, Anna; Guida, Stefania; Maida, Imma; Cocco, Tiziana; Passarelli, Anna; Quaresmini, Davide; Franzese, Ornella; Palermo, Belinda; Di Donna, Cosmo; Sperduti, Isabella; Foddai, MariaLaura; Stabile, Helena; Gismondi, Angela; Santoni, Angela; Nisticò, Paola; Sponghini, Andrea P; Platini, Francesca; Marra, Elena; Rondonotti, David; Alabiso, Oscar; Fierro, Maria T; Savoia, Paola; Stratica, Florian; Quaglino, Pietro; Di Monta, Gianluca; Corrado, Caracò; Di Marzo, Massimiliano; Ugo, Marone; Di Cecilia, Maria Luisa; Nicola, Mozzillo; Fusciello, Celeste; Marra, Antonio; Guarrasi, Rosario; Baldi, Carlo; Russo, Rosa; Di Giulio, Giovanni; Faiola, Vincenzo; Zeppa, Pio; Pepe, Stefano; Gambale, Elisabetta; Carella, Consiglia; Di Paolo, Alessandra; De Tursi, Michele; Marra, Laura; De Murtas, Fara; Sorrentino, Valeria; Voinea, Silviu; Panaitescu, Eugenia; Bolovan, Madalina; Stanciu, Adina; Cinca, Sabin; Botti, Chiara; Aquino, Gabriella; Anniciello, Annamaria; Fortes, Cristina; Mastroeni, Simona; Caggiati, Alessio; Passarelli, Francesca; Zappalà, Alba; Capuano, Maria; Bono, Riccardo; Nudo, Maurizio; Marino, Claudia; Michelozzi, Paola; De Biasio, Valeria; Battarra, Vincenzo C; Formenti, Silvia; Ascierto, Maria Libera; McMiller, Tracee L; Berger, Alan E; Danilova, Ludmila; Anders, Robert A; Netto, George J; Xu, Haiying; Pritchard, Theresa S; Fan, Jinshui; Cheadle, Chris; Cope, Leslie; Drake, Charles G; Pardoll, Drew M; Taube, Janis M; Topalian, Suzanne L; Gnjatic, Sacha; Nataraj, Sarah; Imai, Naoko; Rahman, Adeeb; Jungbluth, Achim A; Pan, Linda; Venhaus, Ralph; Park, Andrew; Lehmann, Frédéric F; Lendvai, Nikoletta; Cohen, Adam D; Cho, Hearn J; Daniel, Speiser; Hirsh, Vera

Year: 2024

Venue: Theses

DOI: https://www.ncbi.nlm.nih.gov/pubmed/27461275

Thesis PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers

Kristeleit, R; Leary, A; Oaknin, A et al. · 2024 · Theses · DOI

Full title: PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers

Authors: Kristeleit, R; Leary, A; Oaknin, A; Redondo, A; George, A; Chui, S; Seiller, A; Liste-Hermoso, M; Willis, J; Shemesh, CS; Xiao, J; Lin, KK; Molinero, L; Guan, Y; Ray-Coquard, I; Mileshkin, L

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/349647

Thesis PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma

Pinato, David; Cortellini, Alessio; Sukumaran, Ajithkumar et al. · 2021 · Theses · DOI

Full title: PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma

Authors: Pinato, David; Cortellini, Alessio; Sukumaran, Ajithkumar; Cole, tom; Pai, madhava; Habib, Nagy; Spalding, Duncan; Sodergren, Mikael; Martinez, Maria; Dhillon, Tony; Tait, Paul; Thomas, Robert; Ward, Caroline; Kocher, Hemant; Yip, Vincent; Slater, Sarah; Sharma, Rohini

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/10044/1/88610

Thesis Tumor Interferon Signaling Initiates And Sustains A Multigenic Resistance Program To Immune Checkpoint Blockade

Benci, Joseph Lawrence · 2023 · Theses · DOI

Full title: Tumor Interferon Signaling Initiates And Sustains A Multigenic Resistance Program To Immune Checkpoint Blockade

Authors: Benci, Joseph Lawrence

Year: 2023

Venue: Theses

DOI: https://repository.upenn.edu/handle/20.500.14332/29076

Thesis Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · Theses · DOI

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/11343/357926

Thesis Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

UNICIT consortium · 2023 · Theses · DOI

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Authors: UNICIT consortium

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/450123

Thesis The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network

Voskens, Caroline J; Goldinger, Simone M; Loquai, Carmen et al. · 2013 · Theses · DOI

Full title: The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network

Authors: Voskens, Caroline J;Goldinger, Simone M;Loquai, Carmen;Robert, Caroline;Kaehler, Katharina C;Berking, Carola;Bergmann, Tanja;Bockmeyer, Clemens L;Eigentler, Thomas;Fluck, Michael;Garbe, Claus;Gutzmer, Ralf;Grabbe, Stephan;Hauschild, Axel;Hein, Rüdiger;Hundorfean, Gheorghe;Justich, Armin;Keller, Ullrich;Klein, Christina;Mateus, Christine;Mohr, Peter;Paetzold, Sylvie;Satzger, Imke;Schadendorf, Dirk;Schlaeppi, Marc;Schuler, Gerold;Schuler-Thurner, Beatrice;Trefzer, Uwe;Ulrich, Jens;Vaubel, Julia;von Moos, Roger;Weder, Patrik;Wilhelm, Tabea;Göppner, Daniela;Dummer, Reinhard;Heinzerling, Lucie M

Year: 2013

Venue: Theses

DOI: https://mediatum.ub.tum.de/1210836

Thesis Peripheral blood TCR repertoire profiling may facilitate patient stratification for immunotherapy against melanoma

Hogan, Sabrina A.; Courtier, Anaïs; Cheng, Phil F. et al. · 2025 · Theses · DOI

Full title: Peripheral blood TCR repertoire profiling may facilitate patient stratification for immunotherapy against melanoma

Authors: Hogan, Sabrina A.; Courtier, Anaïs; Cheng, Phil F.; Jaberg-Bentele, Nicoletta F.; Goldinger, Simone M.; Manuel, Manuarii; Perez, Solène; Plantier, Nadia; Mouret, Jean-François; Nguyen-Kim, Thi Dan Linh; Raaijmakers, Marieke I.G.; Kvistborg, Pia; Pasqual, Nicolas; Haanen, John B.A.G.; Dummer, Reinhard; Levesque, Mitchell P.

Year: 2025

Venue: Theses

DOI: https://hdl.handle.net/20.500.14716/199769

Thesis Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M et al. · 2024 · Theses · DOI

Full title: Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/435302

Thesis Study of immunomics and immune regulation in ovarian cancer

Abdul Aziz, Nor Haslinda · 2015 · Imperial College London · DOI

Full title: Study of immunomics and immune regulation in ovarian cancer

Authors: Abdul Aziz, Nor Haslinda

Year: 2015

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/23897

Thesis Targeting Myeloid Derived Suppressor Cells enhances the response of immune checkpoint inhibitor

Abood, David · 2022 · Theses · DOI

Full title: Targeting Myeloid Derived Suppressor Cells enhances the response of immune checkpoint inhibitor

Authors: Abood, David

Year: 2022

Venue: Theses

DOI: http://hdl.handle.net/1811/102492

Thesis Checkpoint inhibitors for malignant melanoma: a systematic review and meta-analysis

Karlsson, A; Saleh, SN · 2017 · Theses · DOI

Full title: Checkpoint inhibitors for malignant melanoma: a systematic review and meta-analysis

Authors: Karlsson, A; Saleh, SN

Year: 2017

Venue: Theses

DOI: http://hdl.handle.net/10044/1/44053

Thesis Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff et al. · 2020 · Theses · DOI

Full title: Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Authors: Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff; Nielsen, Morten; Borch, Troels Holz; Olsen, Lars Rønn; id_orcid 0000-0002-6725-7850; Aasbjerg, Gitte; Santegoets, Saskia J.; van der Burg, Sjoerd H.; Milne, Katy; Nelson, Brad H.; Met, Özcan; Donia, Marco; Svane, Inge Marie

Year: 2020

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191

Thesis Prior corticosteroid treatment alters cPBMC composition and IFNγ response to immunotherapy in canine cancer

Zimmermann, Anna Barbara Emilia; Taskoparan, Betül; Fuchs, Daniel et al. · 2025 · Theses · DOI

Full title: Prior corticosteroid treatment alters cPBMC composition and IFNγ response to immunotherapy in canine cancer

Authors: Zimmermann, Anna Barbara Emilia; Taskoparan, Betül; Fuchs, Daniel; https://orcid.org/0009-0007-1472-4391; Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Maheswaran, Mathischan; Schnyder, Manuela; https://orcid.org/0000-0002-6523-7952; Hartnack, Sonja; https://orcid.org/0000-0002-5757-5708; Rohrer Bley, Carla; https://orcid.org/0000-0002-5733-2722; vom Berg, Johannes; https://orcid.org/0000-0002-4086-1564

Year: 2025

Venue: Theses

DOI: oai:www.zora.uzh.ch:20.500.14742/230954

Thesis Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

Virassamy, B; Caramia, F; Savas, P et al. · 2023 · Theses · DOI

Full title: Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

Authors: Virassamy, B; Caramia, F; Savas, P; Sant, S; Wang, J; Christo, SN; Byrne, A; Clarke, K; Brown, E; Teo, ZL; von Scheidt, B; Freestone, D; Gandolfo, LC; Weber, K; Teply-Szymanski, J; Li, R; Luen, SJ; Denkert, C; Loibl, S; Lucas, O; Swanton, C; Speed, TP; Darcy, PK; Neeson, PJ; Mackay, LK; Loi, S

Year: 2023

Venue: Theses

DOI: https://hdl.handle.net/11343/332440

Thesis RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.

Heidegger, Simon; Kreppel, Diana; Bscheider, Michael et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.

Authors: Heidegger, Simon;Kreppel, Diana;Bscheider, Michael;Stritzke, Florian;Nedelko, Tatiana;Wintges, Alexander;Bek, Sarah;Fischer, Julius C;Graalmann, Theresa;Kalinke, Ulrich;Bassermann, Florian;Haas, Tobias;Poeck, Hendrik

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588738

Thesis Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo

Reijers, Irene L.M.; Menzies, Alexander M.; Lopez-Yurda, Marta et al. · 2025 · Theses · DOI

Full title: Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo

Authors: Reijers, Irene L.M.; Menzies, Alexander M.; Lopez-Yurda, Marta; Versluis, Judith M.; Rozeman, Elisa A.; Saw, Robyn P.M.; van Houdt, Winan J.; Kapiteijn, Ellen; van der Veldt, Astrid A.M.; Suijkerbuijk, Karijn P.M.; Eriksson, Hanna; Hospers, Geke A.P.; Klop, Willem M.C.; Torres Acosta, Alejandro; Grijpink-Ongering, Lindsay; Gonzalez, Maria; van der Wal, Anja; Al-Mamgani, Abrahim; Spillane, Andrew J.; Scolyer, Richard A.; van de Wiel, Bart A.; van Akkooi, Alexander C.J.; Long, Georgina V.; Blank, Christian U.

Year: 2025

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/459344

Thesis Multiplex immunohistochemistry elucidates increased distance between cytotoxic T cells and plasma cells in relapsed myeloma, and identifies Lag-3 as the most common checkpoint receptor on cytotoxic T cells of myeloma patients

Ninkovic, S; Purton, LE; Harrison, SJ et al. · 2024 · Theses · DOI

Full title: Multiplex immunohistochemistry elucidates increased distance between cytotoxic T cells and plasma cells in relapsed myeloma, and identifies Lag-3 as the most common checkpoint receptor on cytotoxic T cells of myeloma patients

Authors: Ninkovic, S; Purton, LE; Harrison, SJ; Quach, H

Year: 2024

Venue: Theses

DOI: https://hdl.handle.net/11343/348206

Thesis 50 years of systemic therapy of urinary bladder cancer

Retz, Margitta; von Amsberg, Gunhild; Horn, Thomas et al. · 2019 · Theses · DOI

Full title: 50 years of systemic therapy of urinary bladder cancer

Authors: Retz, Margitta;von Amsberg, Gunhild;Horn, Thomas;Gschwend, Juergen E.;Maisch, Philipp

Year: 2019

Venue: Theses

DOI: https://mediatum.ub.tum.de/1588421

Thesis Neo-adjuvant immunotherapy emerges as best medical practice, and will be the new standard of care for macroscopic stage III melanoma

van Akkooi, Alexander C.J.; Blank, Christian; Eggermont, Alexander M.M. · 2023 · Theses · DOI

Full title: Neo-adjuvant immunotherapy emerges as best medical practice, and will be the new standard of care for macroscopic stage III melanoma

Authors: van Akkooi, Alexander C.J.; Blank, Christian; Eggermont, Alexander M.M.

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/458632

Thesis The role and mechanisms of interleukin-9 in facilitating anticancer effect of immune checkpoint blockade in lung cancer animal model

Feng, Yuqian; 馮玉倩 · 2023 · Theses · DOI

Full title: The role and mechanisms of interleukin-9 in facilitating anticancer effect of immune checkpoint blockade in lung cancer animal model

Authors: Feng, Yuqian; 馮玉倩

Year: 2023

Venue: Theses

DOI: https://hub.hku.hk/handle/10722/327888

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke et al. · 2017 · Theses · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke; Rosenkrantz, Lisbet Holmich; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/25caf41f-8965-4658-b672-f62d5d7ff1d3

Thesis The effects of novel immune checkpoint inhibitors on melanoma patient's immune system

Kasanen, Henna · 2023 · Theses · DOI

Full title: The effects of novel immune checkpoint inhibitors on melanoma patient's immune system

Authors: Kasanen, Henna

Year: 2023

Venue: Theses

DOI: http://hdl.handle.net/10138/566654

Thesis Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

Gide, TN; Quek, C; Menzies, AM et al. · 2019 · Theses · DOI

Full title: Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

Authors: Gide, TN; Quek, C; Menzies, AM; Tasker, AT; Shang, P; Holst, J ; https://orcid.org/0000-0002-0377-9318; Madore, J; Lim, SY; Velickovic, R; Wongchenko, M; Yan, Y; Lo, S; Carlino, MS; Guminski, A; Saw, RPM; Pang, A ; https://orcid.org/0000-0003-1001-5102; McGuire, HM; Palendira, U; Thompson, JF; Rizos, H; Silva, IPD; Batten, M; Scolyer, RA; Long, GV; Wilmott, JS

Year: 2019

Venue: Theses

DOI: http://hdl.handle.net/1959.4/unsworks_75518

Thesis Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff et al. · 2020 · Theses · DOI

Full title: Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Year: 2020

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191

Thesis Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers et al. · 2015 · Theses · DOI

Full title: Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Authors: Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers; id_orcid 0000-0003-3147-6960

Year: 2015

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/66a425e1-b542-4f31-9f8e-8ef59b388018

Thesis Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor- reactive CD8+T cells and reprogramming macrophages

Tichet, Melanie; Wullschleger, Stephan; Chryplewicz, Agnieszka et al. · 2023 · Theses · DOI

Full title: Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor- reactive CD8+T cells and reprogramming macrophages

Authors: Tichet, Melanie; Wullschleger, Stephan; Chryplewicz, Agnieszka; Fournier, Nadine; Marcone, Rachel; Kauzlaric, Annamaria; Homicsko, Krisztian; Deak, Laura Codarri; Umana, Pablo; Klein, Christian; Hanahan, Douglas

Year: 2023

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/197503

Thesis Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer

Powles, Thomas; Albiges, Laurence; Staehler, Michael et al. · 2018 · Theses · DOI

Full title: Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer

Authors: Powles, Thomas; Albiges, Laurence; Staehler, Michael; Bensalah, Karim; Dabestani, Saeed; Giles, Rachel H.; Hofmann, Fabian; Hora, Milan; Kuczyk, Markus A.; Lam, Thomas B.; Marconi, Lorenzo; Merseburger, Axel S.; Fernández-Pello, Sergio; Tahbaz, Rana; Volpe, Alessandro; Ljungberg, Börje; Bex, Axel

Year: 2018

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/364122

Thesis Adjuvant treatment for melanoma in clinical practice – Trial versus reality

de Meza, Melissa M.; Ismail, Rawa K.; Rauwerdink, Daan et al. · 2021 · Theses · DOI

Full title: Adjuvant treatment for melanoma in clinical practice – Trial versus reality

Authors: de Meza, Melissa M.; Ismail, Rawa K.; Rauwerdink, Daan; van Not, Olivier J.; van Breeschoten, Jesper; Blokx, Willeke A.M.; de Boer, Anthonius; van Dartel, Maaike; Hilarius, Doranne L.; Ellebaek, Eva; Bonenkamp, Han J.; Blank, Christian U.; Aarts, Maureen J.B.; van Akkooi, Alexander C.J.; van den Berkmortel, Franchette W.P.J.; Boers-Sonderen, Marye J.; de Groot, Jan Willem B.; Haanen, John B.; Hospers, Geke A.P.; Kapiteijn, Ellen W.; Piersma, Djura; van Rijn, Roos S.; van der Veldt, Astrid A.M.; Vreugdenhil, Art; Westgeest, Hans M.; van den Eertwegh, Alfons J.M.; Suijkerbuijk, Karijn P.M.; Wouters, Michel W.J.M.

Year: 2021

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/443820

Thesis Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice

Singh, Akashdip; Mommers-Elshof, Eline T A M; Vijver, Saskia V et al. · 2024 · Theses · DOI

Full title: Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice

Authors: Singh, Akashdip; Mommers-Elshof, Eline T A M; Vijver, Saskia V; Jansen, J H Marco; Gonder, Susanne; Lebbink, Robert Jan; Bihan, Dominique; Farndale, Richard W; Boon, Louis; Langermann, Solomon; Leusen, Jeanette H W; Flies, Dallas; Meyaard, Linde; Pascoal Ramos, M Ines

Year: 2024

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/451136

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjoern, Jon; Lyngaa, Rikke; Andersen, Rikke et al. · 2017 · Theses · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjoern, Jon; Lyngaa, Rikke; Andersen, Rikke; Rosenkrantz, Lisbet Hölmich; Hadrup, Sine Reker; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: Theses

DOI: https://researchprofiles.ku.dk/da/publications/a922dd04-bba2-4ccc-adac-af06273d2557

Thesis Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander M.A. et al. · 2021 · Theses · DOI

Full title: Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Authors: Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander M.A.; Lieuwes, Natasja G.; Biemans, Rianne; Lieverse, Relinde I.Y.; Neri, Dario; id_orcid0000-0001-5234-7370; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J.; Lambin, Philippe

Year: 2021

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/475414

Thesis Facilitating cancer immunotherapies with armed oncolytic adenoviruses

Quixabeira, Dafne · 2023 · Theses · DOI

Full title: Facilitating cancer immunotherapies with armed oncolytic adenoviruses

Authors: Quixabeira, Dafne

Year: 2023

Venue: Theses

DOI: http://hdl.handle.net/10138/563364

Thesis Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers et al. · 2015 · Theses · DOI

Full title: Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Authors: Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers; id_orcid 0000-0003-3147-6960

Year: 2015

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/66a425e1-b542-4f31-9f8e-8ef59b388018

Thesis The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Martins, Filipe; Schiappacasse, Luis; Levivier, Marc et al. · 2020 · Theses · DOI

Full title: The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Authors: Martins, Filipe; Schiappacasse, Luis; Levivier, Marc; Tuleasca, Constantin; Cuendet, Michel A.; Aedo-Lopez, Veronica; Gautron Moura, Bianca; Homicsko, Krisztian; Bettini, Adrienne; Berthod, Gregoire; Gerard, Camille L.; Wicky, Alexandre; Bourhis, Jean; Michielin, Olivier

Year: 2020

Venue: Theses

DOI: https://infoscience.epfl.ch/handle/20.500.14299/166853

Thesis Durable antitumor responses to CD47 blockade require adaptive immune stimulation

Sockolosky, Jonathan T.; Ho, Chia Chi M.; Almo, Steven C. et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Durable antitumor responses to CD47 blockade require adaptive immune stimulation

Authors: Sockolosky, Jonathan T.; Ho, Chia Chi M.; Almo, Steven C.; Garcia, K. Christopher; Dougan, Michael; Kauke, Monique Jacqueline; Ploegh, Hidde; Ingram, Jessica R.

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/105539

Thesis Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy

Chiu, CY; Chang, JJ; Dantanarayana, AI et al. · 2023 · Theses · DOI

Full title: Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy

Authors: Chiu, CY; Chang, JJ; Dantanarayana, AI; Solomon, A; Evans, VA; Pascoe, R; Gubser, C; Trautman, L; Fromentin, R; Chomont, N; McMahon, JH; Cameron, PU; Rasmussen, TA; Lewin, SR

Year: 2023

Venue: Theses

DOI: https://hdl.handle.net/11343/333694

Thesis The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021 · Theses · DOI

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Year: 2021

Venue: Theses

DOI: https://www.repository.cam.ac.uk/handle/1810/326323

Thesis Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben et al. · 2021 · Theses · DOI

Full title: Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Authors: Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben; Rohrberg, Kristoffer; Reker Hadrup, Sine; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2021

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/a2066594-9c4f-4789-98cd-954e4dedb11a

Thesis Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted

Kraehenbuehl, Lukas; Winkelbeiner, Nicola; Turko, Patrick et al. · 2025 · Theses · DOI

Full title: Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted

Authors: Kraehenbuehl, Lukas; Winkelbeiner, Nicola; Turko, Patrick; Staeger, Ramon; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Kaiser, Vivienn; Stadler, Pia-Charlotte; Nordmann, Thierry M.; Brüggen, Marie-Charlotte; Levesque, Mitchell P.; Contassot, Emmanuel; French, Lars E.; Dummer, Reinhard; Meier-Schiesser, Barbara

Year: 2025

Venue: Theses

DOI: http://hdl.handle.net/20.500.11850/742827

Thesis High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial

van Dorp, Jeroen; Pipinikas, Christodoulos; Suelmann, Britt B.M. et al. · 2023 · Theses · DOI

Full title: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial

Authors: van Dorp, Jeroen; Pipinikas, Christodoulos; Suelmann, Britt B.M.; Mehra, Niven; van Dijk, Nick; Marsico, Giovanni; van Montfoort, Maurits L.; Hackinger, Sophie; Braaf, Linde M.; Amarante, Tauanne; van Steenis, Charlaine; McLay, Kirsten; Daletzakis, Antonios; van den Broek, Daan; van de Kamp, Maaike W.; Hendricksen, Kees; de Feijter, Jeantine M.; Boellaard, Thierry N.; Meijer, Richard P.; van der Heijden, Toine G.; Rosenfeld, Nitzan; van Rhijn, Bas W.G.; Jones, Greg; van der Heijden, Michiel S.

Year: 2023

Venue: Theses

DOI: https://dspace.library.uu.nl/handle/1874/448678

Thesis **Authors:** Orlen, Margo, Isabelle **Institution:** University of Pennsylvania **Date:** 2025-09-02T16:22:50Z

Orlen, Margo, Isabelle · 2025 · Theses · DOI

Full title: **Authors:** Orlen, Margo, Isabelle **Institution:** University of Pennsylvania **Date:** 2025-09-02T16:22:50Z

Authors: Orlen, Margo, Isabelle

Year: 2025

Venue: Theses

DOI: https://repository.upenn.edu/handle/20.500.14332/61644

Thesis Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise et al. · 2022 · Theses · DOI

Full title: Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Year: 2022

Venue: Theses

DOI: https://orbit.dtu.dk/en/publications/7ba8c0c4-d95a-4084-9cc1-ebe6ba9f1cb6

Thesis Current status of immunotherapy in gastrointestinal malignancies

Lorenzen, Sylvie; Lordick, Florian; Loosen, Sven Heiko et al. · 2020 · Theses · DOI

Full title: Current status of immunotherapy in gastrointestinal malignancies

Authors: Lorenzen, Sylvie;Lordick, Florian;Loosen, Sven Heiko;Tacke, Frank;Trautwein, Christian;Roderburg, Christoph;Ettrich, Thomas J;Perkhofer, Lukas;Reinacher-Schick, Anke;Stein, Alexander

Year: 2020

Venue: Theses

DOI: https://mediatum.ub.tum.de/1588789

Thesis Understanding the pathogenesis of immune checkpoint inhibitor-induced hepatitis

Gudd, Cathrin Luisa Carolin · 2021 · Imperial College London · DOI

Full title: Understanding the pathogenesis of immune checkpoint inhibitor-induced hepatitis

Authors: Gudd, Cathrin Luisa Carolin

Year: 2021

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/85786

Thesis The Role of the Innate Immune System in the Treatment Response of Advanced Melanoma Patients Treated with Immunotherapy

Lee, Hansol · 2021 · University of Sydney · DOI

Full title: The Role of the Innate Immune System in the Treatment Response of Advanced Melanoma Patients Treated with Immunotherapy

Authors: Lee, Hansol

Year: 2021

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/25704

Patent us-2019119376-a1

· 2019

Full title: us-2019119376-a1

Year: 2019

Patent us-2018169230-a1

· 2018

Full title: us-2018169230-a1

Year: 2018

Patent us-9713641-b2

· 2017

Full title: us-9713641-b2

Year: 2017

Patent us-2024117037-a1

· 2024

Full title: us-2024117037-a1

Year: 2024

Patent us-2022002410-a1

· 2022

Full title: us-2022002410-a1

Year: 2022

Patent us-2022135682-a1

· 2022

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2. Data Extraction

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Paper

The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials.

Pu, Wenji, Li, Shasha, Zhang, Jinliang, Huang, Jijie, Li, Jishi, Jiang, Yong, Xu, Zhiyuan, Yi, Fan, Lan, Yuling, Xiao, Qin, Chen, Wenqi, Jin, Jing · 2025

Authors: Pu, Wenji, Li, Shasha, Zhang, Jinliang, Huang, Jijie, Li, Jishi, Jiang, Yong, Xu, Zhiyuan, Yi, Fan, Lan, Yuling, Xiao, Qin, Chen, Wenqi, Jin, Jing

DOI: https://doi.org/10.3389/fimmu.2025.1566939

Paper

Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer

Yaqi Zhu · 2023

Full title: Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer

Authors: Yaqi Zhu

DOI: https://doi.org/10.54097/pjjvd009

Paper

Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy

Pan, Chong-xian, Liu, Hongtao, Robins, Elizabeth, Song, Wenru, Liu, Delong, Li, Zihai, Zheng, Lei · 2020

Full title: Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy

Authors: Pan, Chong-xian, Liu, Hongtao, Robins, Elizabeth, Song, Wenru, Liu, Delong, Li, Zihai, Zheng, Lei

DOI: https://doi.org/10.1186/s13045-020-00862-w

Paper

Immune Therapeutics in the Treatment of Advanced Gastric and Esophageal Cancer

R. Park, S. Williamson, A. Kasi, A. Saeed · 2018

Full title: Immune Therapeutics in the Treatment of Advanced Gastric and Esophageal Cancer

Authors: R. Park, S. Williamson, A. Kasi, A. Saeed

DOI: https://doi.org/10.21873/anticanres.12891

Paper

Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma.

Heinrich, Bernd, Ruf, Benjamin, Subramanyam, Varun, Myojin, Yuta, Lai, Chunwei W, Craig, Amanda J, Fu, Jianyang, Xie, Changqing, Kroemer, Alexander, Greten, Tim F, Korangy, Firouzeh · 2022

Full title: Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma.

Authors: Heinrich, Bernd, Ruf, Benjamin, Subramanyam, Varun, Myojin, Yuta, Lai, Chunwei W, Craig, Amanda J, Fu, Jianyang, Xie, Changqing, Kroemer, Alexander, Greten, Tim F, Korangy, Firouzeh

DOI: https://doi.org/10.3389/fimmu.2022.849958

Paper

Indicators of responsiveness to immune checkpoint inhibitors.

Full title: Indicators of responsiveness to immune checkpoint inhibitors.

DOI: https://doi.org/10.1038/s41598-017-01000-2

Paper

To be, or not to be immunocompetent.

Volk, Hans-Dieter, Reinke, Petra · 2013

Full title: To be, or not to be immunocompetent.

Authors: Volk, Hans-Dieter, Reinke, Petra

DOI: https://doi.org/10.1186/cc12897

Paper

Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies.

Hernandez, Carlos, Arasanz, Hugo, Chocarro, Luisa, Bocanegra, Ana, Zuazo, Miren, Fernandez-Hinojal, Gonzalo, Blanco, Ester, Vera, Ruth, Escors, David, Kochan, Grazyna · 2020

Full title: Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies.

Authors: Hernandez, Carlos, Arasanz, Hugo, Chocarro, Luisa, Bocanegra, Ana, Zuazo, Miren, Fernandez-Hinojal, Gonzalo, Blanco, Ester, Vera, Ruth, Escors, David, Kochan, Grazyna

DOI: https://doi.org/10.3390/ijms21072411

Paper

The bladder cancer immune micro-environment in the context of response to immune checkpoint inhibition.

van Dorp, Jeroen, van der Heijden, Michiel S · 2023

Full title: The bladder cancer immune micro-environment in the context of response to immune checkpoint inhibition.

Authors: van Dorp, Jeroen, van der Heijden, Michiel S

DOI: https://doi.org/10.3389/fimmu.2023.1235884

Paper

Endometrial Carcinoma: Immune Microenvironment and Emerging Treatments in Immuno-Oncology.

Rousset-Rouviere, Sandrine, Rochigneux, Philippe, Chrétien, Anne-Sophie, Fattori, Stéphane, Gorvel, Laurent, Provansal, Magali, Lambaudie, Eric, Olive, Daniel, Sabatier, Renaud · 2021

Full title: Endometrial Carcinoma: Immune Microenvironment and Emerging Treatments in Immuno-Oncology.

Authors: Rousset-Rouviere, Sandrine, Rochigneux, Philippe, Chrétien, Anne-Sophie, Fattori, Stéphane, Gorvel, Laurent, Provansal, Magali, Lambaudie, Eric, Olive, Daniel, Sabatier, Renaud

DOI: https://doi.org/10.3390/biomedicines9060632

Paper

Influence of age on the efficacy of immune checkpoint inhibitors in advanced cancers: a systematic review and meta-analysis.

Full title: Influence of age on the efficacy of immune checkpoint inhibitors in advanced cancers: a systematic review and meta-analysis.

DOI: https://doi.org/10.1080/0284186X.2019.1695062

Paper

Hepatocellular Carcinoma: An Overview of the Changing Landscape of Treatment Options

Koulouris, Andreas, Tsagkaris, Christos, Spyrou, V., Pappa, Eleni V., Troullinou, Aikaterini, Nikolaou, Michail · 2021

Full title: Hepatocellular Carcinoma: An Overview of the Changing Landscape of Treatment Options

Authors: Koulouris, Andreas, Tsagkaris, Christos, Spyrou, V., Pappa, Eleni V., Troullinou, Aikaterini, Nikolaou, Michail

DOI: https://doi.org/10.2147/jhc.s300182

Paper

Emerging immunotherapy and tumor microenvironment for advanced sarcoma: a comprehensive review.

Huang, Hai, Fan, Yiwei, Zhang, Shuling, Bai, Xueli, Wang, Xiaonan, Shan, Fengping · 2025

Full title: Emerging immunotherapy and tumor microenvironment for advanced sarcoma: a comprehensive review.

Authors: Huang, Hai, Fan, Yiwei, Zhang, Shuling, Bai, Xueli, Wang, Xiaonan, Shan, Fengping

DOI: https://doi.org/10.3389/fimmu.2025.1507870

Paper

Pulmonary Toxicities Associated With the Use of Immune Checkpoint Inhibitors: An Update From the Immuno-Oncology Subgroup of the Neutropenia, Infection & Myelosuppression Study Group of the Multinational Association for Supportive Care in Cancer.

Rapoport, Bernardo L, Shannon, Vickie R, Cooksley, Tim, Johnson, Douglas B, Anderson, Lindsay, Blidner, Ada G, Tintinger, Gregory R, Anderson, Ronald · 2021

Authors: Rapoport, Bernardo L, Shannon, Vickie R, Cooksley, Tim, Johnson, Douglas B, Anderson, Lindsay, Blidner, Ada G, Tintinger, Gregory R, Anderson, Ronald

DOI: https://doi.org/10.3389/fphar.2021.743582

Paper

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Bjoern, Jon, Lyngaa, Rikke, Andersen, Rikke, Hölmich, Lisbet Rosenkrantz, Hadrup, Sine Reker, Donia, Marco, Svane, Inge Marie · 2017

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Authors: Bjoern, Jon, Lyngaa, Rikke, Andersen, Rikke, Hölmich, Lisbet Rosenkrantz, Hadrup, Sine Reker, Donia, Marco, Svane, Inge Marie

DOI: https://doi.org/10.18632/oncotarget.16003

Paper

Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients.

Marable, Jonathan, Ruiz, Damien, Jaiswal, Anil K, Bhattacharya, Ritankar, Pantazes, Robert, Agarwal, Payal, Suryawanshi, Amol S, Bedi, Deepa, Mishra, Amarjit, Smith, Bruce F, Sandey, Maninder · 2021

Full title: Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients.

DOI: https://doi.org/10.1038/s41598-021-00325-3

Paper

Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for internists and general practitioners.

Wojtukiewicz, Marek Z, Rek, Magdalena M, Karpowicz, Kamil, Górska, Maria, Polityńska, Barbara, Wojtukiewicz, Anna M, Moniuszko, Marcin, Radziwon, Piotr, Tucker, Stephanie C, Honn, Kenneth V · 2021

Full title: Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for internists and general practitioners.

DOI: https://doi.org/10.1007/s10555-021-09976-0

Paper

From Bench to Bladder: The Rise in Immune Checkpoint Inhibition in the Treatment of Non-Muscle Invasive Bladder Cancer.

Burns, Caitlin P, Parker, Jacob M, Schaap, Dylan M, Wakefield, Mark R, Fang, Yujiang · 2025

Full title: From Bench to Bladder: The Rise in Immune Checkpoint Inhibition in the Treatment of Non-Muscle Invasive Bladder Cancer.

Authors: Burns, Caitlin P, Parker, Jacob M, Schaap, Dylan M, Wakefield, Mark R, Fang, Yujiang

DOI: https://doi.org/10.3390/cancers17071135

Paper

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping · 2020

Full title: Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Authors: Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping

DOI: https://doi.org/10.3389/fimmu.2020.01708

Paper

Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment

Wang, Jiewen, Kang, Guangbo, Yuan, Haibin, Cao, Xiaocang, Huang, He, Marco, Ario de · 2022

Full title: Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment

Authors: Wang, Jiewen, Kang, Guangbo, Yuan, Haibin, Cao, Xiaocang, Huang, He, Marco, Ario de

DOI: https://doi.org/10.3389/fimmu.2021.838082

Paper

An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma

Huang, Yaxuan, Lan, Yunyun, Zhang, Zhe, Xiao, Xue, Huang, Tingting · 2022

Full title: An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma

Authors: Huang, Yaxuan, Lan, Yunyun, Zhang, Zhe, Xiao, Xue, Huang, Tingting

DOI: https://doi.org/10.3389/fonc.2022.800315

Paper

Immunopathogenesis of Immune Checkpoint Inhibitor-Related Adverse Events: Roles of the Intestinal Microbiome and Th17 Cells.

Anderson, Ronald, Theron, Annette J, Rapoport, Bernardo L · 2019

Full title: Immunopathogenesis of Immune Checkpoint Inhibitor-Related Adverse Events: Roles of the Intestinal Microbiome and Th17 Cells.

Authors: Anderson, Ronald, Theron, Annette J, Rapoport, Bernardo L

DOI: https://doi.org/10.3389/fimmu.2019.02254

Paper

Immunotherapy in Treating EGFR-Mutant Lung Cancer: Current Challenges and New Strategies

To, Kenneth K.W., Fong, Winnie, Cho, William C. · 2021

Full title: Immunotherapy in Treating EGFR-Mutant Lung Cancer: Current Challenges and New Strategies

Authors: To, Kenneth K.W., Fong, Winnie, Cho, William C.

DOI: https://doi.org/10.3389/fonc.2021.635007

Paper

The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

Full title: The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

DOI: https://doi.org/10.18632/oncotarget.22242

Paper

Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions.

Full title: Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions.

DOI: https://doi.org/10.3390/cells10082044

Paper

Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.

Majumder, Biswanath, Datta, Santanu · 2025

Full title: Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.

Authors: Majumder, Biswanath, Datta, Santanu

DOI: https://doi.org/10.3389/fimmu.2025.1676702

Paper

Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials.

Full title: Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials.

DOI: https://doi.org/10.3390/jcm7120542

Paper

Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas · 2019

Full title: Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Authors: Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas

DOI: https://doi.org/10.1371/journal.pone.0219517

Paper

The role of BRAF V600 mutation in melanoma

P. Ascierto, J. Kirkwood, J. Grob, E. Simeone, A. Grimaldi, M. Maio, G. Palmieri, A. Testori, F. Marincola, N. Mozzillo · 2012

Full title: The role of BRAF V600 mutation in melanoma

Authors: P. Ascierto, J. Kirkwood, J. Grob, E. Simeone, A. Grimaldi, M. Maio, G. Palmieri, A. Testori, F. Marincola, N. Mozzillo

DOI: https://doi.org/10.1186/1479-5876-10-85

Paper

Immunotherapy in Triple-Negative Breast Cancer: Present and Future

Kim, Isaac, Sanchez, Katherine, McArthur, Heather L., Page, David B. · 2019

Full title: Immunotherapy in Triple-Negative Breast Cancer: Present and Future

Authors: Kim, Isaac, Sanchez, Katherine, McArthur, Heather L., Page, David B.

DOI: https://doi.org/10.1007/s12609-019-00345-z

Paper

Front-Line ICI-Based Combination Therapy Post-TKI Resistance May Improve Survival in NSCLC Patients With EGFR Mutation

Tian, Tian, Yu, Min, Li, Juan, Jiang, Mao-Qiong, Ma, Daiyuan, Tang, Shubin, Lin, Zhiyu, Chen, Lin, Gong, Youling, Zhu, Jiang, Zhou, Qiang, Huang, Meijuan, Lü, You · 2021

Full title: Front-Line ICI-Based Combination Therapy Post-TKI Resistance May Improve Survival in NSCLC Patients With EGFR Mutation

Authors: Tian, Tian, Yu, Min, Li, Juan, Jiang, Mao-Qiong, Ma, Daiyuan, Tang, Shubin, Lin, Zhiyu, Chen, Lin, Gong, Youling, Zhu, Jiang, Zhou, Qiang, Huang, Meijuan, Lü, You

DOI: https://doi.org/10.3389/fonc.2021.739090

Paper

Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.

Tulunay Virlan, Aysin, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick, Christodoulou, Maria-Ioanna · 2024

Full title: Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects.

Authors: Tulunay Virlan, Aysin, Cafaro, Giacomo, Sunzini, Flavia, Degboe, Yannick, Christodoulou, Maria-Ioanna

DOI: https://doi.org/10.3389/fonc.2024.1476475

Paper

OX40 signaling in cancer immunotherapy: mechanisms of action, translational applications, and therapeutic perspectives.

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Full title: OX40 signaling in cancer immunotherapy: mechanisms of action, translational applications, and therapeutic perspectives.

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Full title: Spatial transcriptomics reveals tumor microenvironment heterogeneity in EBV positive diffuse large B cell lymphoma

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Full title: Maximizing Immunotherapy in Sarcoma Using Histology, Biomarkers and Novel Approaches

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Full title: Clinical Outcomes in Fibrolamellar Hepatocellular Carcinoma Treated with Immune Checkpoint Inhibitors

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Full title: Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.

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Tumor-infiltrating immune cell profiles and changes associate with additional trastuzumab in preoperative chemotherapy for patients with HER2-positive gastric cancer

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Full title: Tumor-infiltrating immune cell profiles and changes associate with additional trastuzumab in preoperative chemotherapy for patients with HER2-positive gastric cancer

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PD‑1/PD‑L1 blockade, a novel strategy for targeting metastatic colorectal cancer: A systematic review and meta‑analysis of randomized trials

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Full title: PD‑1/PD‑L1 blockade, a novel strategy for targeting metastatic colorectal cancer: A systematic review and meta‑analysis of randomized trials

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Full title: The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy.

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Full title: Complete Remission of Vocal Cord Cancer Treated With Low-Dose Ipilimumab Plus Nivolumab Combined With Interleukin-2 and Hyperthermia.

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Full title: Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis.

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Full title: Releasing the brakes: the role of immune checkpoint inhibitors in laryngeal cancer.

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Full title: PD-1/PD-L1 Inhibitors in Cervical Cancer.

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Full title: Double Guard Efficiency and Safety-Overcoming Resistance to Immunotherapy by Blocking or Stimulating Several Immune Checkpoints in Non-Small Cell Lung Cancer Patients.

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Full title: Concurrent immune checkpoint blockade for enhanced cancer immunotherapy utilizing engineered hybrid nanovesicles.

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Full title: Research Status and Future Directions of PD-1/CTLA-4 Bispecific Antibodies in the Treatment of Advanced Hepatocellular Carcinoma

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Full title: Soluble PD-L1: a potential dynamic predictive biomarker for immunotherapy in patients with proficient mismatch repair colorectal cancer.

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Full title: New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer.

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Full title: Editorial: Combination immunotherapy and immune response assessment of brain tumours.

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Full title: Thyroid-related adverse events induced by immune checkpoint inhibitors.

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Full title: Clinical Significance and Molecular Annotation for PD-L1 Negative Advanced Non-Small Cell Lung Cancer with Sensitivity to Responsive to Dual PD-1/CTLA-4 Blockade.

Authors: Wang, Li, Liu, Li, Zhao, Jing, Yu, Xin, Su, Chunxia

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Full title: Cadonilimab (PD-1/CTLA-4 bispecific antibody) combination therapy for driver gene-negative advanced NSCLC: a single-center retrospective real-world study.

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Full title: Tumor microenvironmental modification by the current target therapy for head and neck squamous cell carcinoma.

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Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy.

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Full title: Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy.

Authors: Widmann, Gerlig, Nguyen, Van Anh, Plaickner, Julian, Jaschke, Werner

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TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

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An Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma.

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Full title: An Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma.

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Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma.

Wang, Yongdan, Li, Pan, Mao, Shuai, Mo, Zhuomao, Cao, Zhirui, Luo, Jin, Zhou, Meiling, Liu, Xifeng, Zhang, Shijun, Yu, Ling · 2021

Full title: Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma.

Authors: Wang, Yongdan, Li, Pan, Mao, Shuai, Mo, Zhuomao, Cao, Zhirui, Luo, Jin, Zhou, Meiling, Liu, Xifeng, Zhang, Shijun, Yu, Ling

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Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.

Mendis, S, Gill, S · 2020

Full title: Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.

Authors: Mendis, S, Gill, S

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Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy

Li, Yiliang, Patel, Sapna P., Roszik, Jason, Qin, Yong · 2018

Full title: Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy

Authors: Li, Yiliang, Patel, Sapna P., Roszik, Jason, Qin, Yong

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RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.

Full title: RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.

DOI: https://doi.org/10.1186/s12885-020-07500-1

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Review of PD-1/PD-L1 Inhibitors in Metastatic dMMR/MSI-H Colorectal Cancer.

Oliveira, André F, Bretes, Luís, Furtado, Irene · 2019

Full title: Review of PD-1/PD-L1 Inhibitors in Metastatic dMMR/MSI-H Colorectal Cancer.

Authors: Oliveira, André F, Bretes, Luís, Furtado, Irene

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Costimulatory and coinhibitory immune checkpoint receptors in head and neck cancer: unleashing immune responses through therapeutic combinations.

Davis, Ruth J, Ferris, Robert L, Schmitt, Nicole C · 2016

Full title: Costimulatory and coinhibitory immune checkpoint receptors in head and neck cancer: unleashing immune responses through therapeutic combinations.

Authors: Davis, Ruth J, Ferris, Robert L, Schmitt, Nicole C

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Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.

Kiaie, Seyed Hossein, Salehi-Shadkami, Hossein, Sanaei, Mohammad Javad, Azizi, Marzieh, Shokrollahi Barough, Mahdieh, Nasr, Mohammad Sadegh, Sheibani, Mohammad · 2023

Full title: Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.

Authors: Kiaie, Seyed Hossein, Salehi-Shadkami, Hossein, Sanaei, Mohammad Javad, Azizi, Marzieh, Shokrollahi Barough, Mahdieh, Nasr, Mohammad Sadegh, Sheibani, Mohammad

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Advancing non-small cell lung cancer treatment: the power of combination immunotherapies

Wu, Yuanlin, Yu, Guangmao, Jin, Ketao, Qian, Jun · 2024

Full title: Advancing non-small cell lung cancer treatment: the power of combination immunotherapies

Authors: Wu, Yuanlin, Yu, Guangmao, Jin, Ketao, Qian, Jun

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Immunotherapy-Induced Anterior Hypophysitis.

Pachika, Pranali S, Khanam, Razwana, Faisal, Seemal, Ahmad, Tahreem, Chandrasekhara Pillai, Anjana · 2021

Full title: Immunotherapy-Induced Anterior Hypophysitis.

Authors: Pachika, Pranali S, Khanam, Razwana, Faisal, Seemal, Ahmad, Tahreem, Chandrasekhara Pillai, Anjana

DOI: https://doi.org/10.7759/cureus.16538

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Plasma GDF15 levels associated with circulating immune cells predict the efficacy of PD-1/PD-L1 inhibitor treatment and prognosis in patients with advanced non-small cell lung cancer.

Hong, Green, Sun, Pureum, Chung, Chaeuk, Park, Dongil, Lee, Song-I, Kim, Nayoung, Lee, Seong Eun, Lee, Jeong Eun, Kang, Yea Eun, Kang, Da Hyun · 2023

Full title: Plasma GDF15 levels associated with circulating immune cells predict the efficacy of PD-1/PD-L1 inhibitor treatment and prognosis in patients with advanced non-small cell lung cancer.

Authors: Hong, Green, Sun, Pureum, Chung, Chaeuk, Park, Dongil, Lee, Song-I, Kim, Nayoung, Lee, Seong Eun, Lee, Jeong Eun, Kang, Yea Eun, Kang, Da Hyun

DOI: https://doi.org/10.1007/s00432-022-04500-5

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Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies.

Damei, Isabelle, Caidi, Aziza, Auclin, Edouard, Adam, Julien, Mella, Sébastien, Hasan, Milena, Tartour, Eric, Robert, Caroline, Corgnac, Stéphanie, Mami-Chouaib, Fathia · 2025

Full title: Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies.

Authors: Damei, Isabelle, Caidi, Aziza, Auclin, Edouard, Adam, Julien, Mella, Sébastien, Hasan, Milena, Tartour, Eric, Robert, Caroline, Corgnac, Stéphanie, Mami-Chouaib, Fathia

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Phenotypic and Proteomic Analysis Identifies Hallmarks of Blood Circulating Extracellular Vesicles in NSCLC Responders to Immune Checkpoint Inhibitors

Full title: Phenotypic and Proteomic Analysis Identifies Hallmarks of Blood Circulating Extracellular Vesicles in NSCLC Responders to Immune Checkpoint Inhibitors

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Lymphocyte-activating gene 3 expression in tumor cells predicts immune checkpoint inhibitor response in triple negative breast cancer.

Kim, Ji-Yeon, Kim, Jeehyun, Cho, Eun Yoon, Park, Yeon Hee, Ahn, Jin Seok, Kim, Kyoung-Mee, Im, Young-Hyuck · 2023

Full title: Lymphocyte-activating gene 3 expression in tumor cells predicts immune checkpoint inhibitor response in triple negative breast cancer.

Authors: Kim, Ji-Yeon, Kim, Jeehyun, Cho, Eun Yoon, Park, Yeon Hee, Ahn, Jin Seok, Kim, Kyoung-Mee, Im, Young-Hyuck

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Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity

Full title: Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity

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Revising the Landscape of Cytokine-Induced Killer Cell Therapy in Lung Cancer: Focus on Immune Checkpoint Inhibitors.

Vaseq, Rohulla, Sharma, Amit, Li, Yutao, Schmidt-Wolf, Ingo G H · 2023

Full title: Revising the Landscape of Cytokine-Induced Killer Cell Therapy in Lung Cancer: Focus on Immune Checkpoint Inhibitors.

Authors: Vaseq, Rohulla, Sharma, Amit, Li, Yutao, Schmidt-Wolf, Ingo G H

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PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake.

Zhang, Jian-Ye, Yan, Yan-Yan, Li, Jia-Jun, Adhikari, Rameshwar, Fu, Li-Wu · 2020

Full title: PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake.

Authors: Zhang, Jian-Ye, Yan, Yan-Yan, Li, Jia-Jun, Adhikari, Rameshwar, Fu, Li-Wu

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Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.

Wang, Xinyao, Zhang, Yuli, Xie, Wei, Liu, Haiying, Cui, Lianghui, Feng, Min · 2025

Full title: Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.

Authors: Wang, Xinyao, Zhang, Yuli, Xie, Wei, Liu, Haiying, Cui, Lianghui, Feng, Min

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Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy.

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Full title: Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy.

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Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

Full title: Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

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Molecular Mechanisms of Cutaneous Immune-Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitors.

Teng, Yi-Shan, Yu, Sebastian · 2023

Full title: Molecular Mechanisms of Cutaneous Immune-Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitors.

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Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

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Full title: Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

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Combination of PD-1/PD-L1 and CTLA-4 inhibitors in the treatment of cancer - a brief update.

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Full title: Combination of PD-1/PD-L1 and CTLA-4 inhibitors in the treatment of cancer - a brief update.

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The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.

Karwacka, Izabela, Obołończyk, Łukasz, Kaniuka-Jakubowska, Sonia, Sworczak, Krzysztof · 2021

Full title: The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.

Authors: Karwacka, Izabela, Obołończyk, Łukasz, Kaniuka-Jakubowska, Sonia, Sworczak, Krzysztof

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The Heart of the Matter: Immune Checkpoint Inhibitors and Immune-Related Adverse Events on the Cardiovascular System.

Green, Chase E, Chacon, Jessica, Godinich, Brandon M, Hock, Rivers, Kiesewetter, Maria, Raynor, Mark, Marwaha, Komal, Maharaj, Satish, Holland, Nathan · 2023

Full title: The Heart of the Matter: Immune Checkpoint Inhibitors and Immune-Related Adverse Events on the Cardiovascular System.

Authors: Green, Chase E, Chacon, Jessica, Godinich, Brandon M, Hock, Rivers, Kiesewetter, Maria, Raynor, Mark, Marwaha, Komal, Maharaj, Satish, Holland, Nathan

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Full title: A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.

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Targeting lymph node delivery with nanovaccines for cancer immunotherapy: recent advances and future directions

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Full title: Targeting lymph node delivery with nanovaccines for cancer immunotherapy: recent advances and future directions

Authors: Li, Yueyi, Shen, Li, Jiang, Zedong, Tan, Keqin, Meng, Yuanling, Zhang, Dingyi, Ma, Xuelei

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Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma.

Petrova, Vera, Arkhypov, Ihor, Weber, Rebekka, Groth, Christopher, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor · 2020

Full title: Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma.

Authors: Petrova, Vera, Arkhypov, Ihor, Weber, Rebekka, Groth, Christopher, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor

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Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies.

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Full title: Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies.

Authors: Tanaka, Ichidai, Koyama, Junji, Itoigawa, Hideyuki, Hayai, Shunsaku, Morise, Masahiro

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Immune Checkpoint Molecules in Hodgkin Lymphoma and Other Hematological Malignancies.

Alibrahim, Mohamed Nazem, Carbone, Antonino, Alsaleh, Noor, Gloghini, Annunziata · 2025

Full title: Immune Checkpoint Molecules in Hodgkin Lymphoma and Other Hematological Malignancies.

Authors: Alibrahim, Mohamed Nazem, Carbone, Antonino, Alsaleh, Noor, Gloghini, Annunziata

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Small-Cell Lung Cancer-An Update on Targeted and Immunotherapies.

McNamee, Nicholas, da Silva, Ines Pires, Nagrial, Adnan, Gao, Bo · 2023

Full title: Small-Cell Lung Cancer-An Update on Targeted and Immunotherapies.

Authors: McNamee, Nicholas, da Silva, Ines Pires, Nagrial, Adnan, Gao, Bo

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Acute interstitial nephritis related to immune checkpoint inhibitors.

Belliere, Julie, Meyer, Nicolas, Mazieres, Julien, Ollier, Sylvie, Boulinguez, Serge, Delas, Audrey, Ribes, David, Faguer, Stanislas · 2016

Full title: Acute interstitial nephritis related to immune checkpoint inhibitors.

Authors: Belliere, Julie, Meyer, Nicolas, Mazieres, Julien, Ollier, Sylvie, Boulinguez, Serge, Delas, Audrey, Ribes, David, Faguer, Stanislas

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Liver graft rejection following immune checkpoint inhibitors treatment: a review.

Hu, Bo, Yang, Xiao-Bo, Sang, Xin-Ting · 2019

Full title: Liver graft rejection following immune checkpoint inhibitors treatment: a review.

Authors: Hu, Bo, Yang, Xiao-Bo, Sang, Xin-Ting

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Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

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Full title: Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

Authors: Chae, Young Kwang, Chung, Su Yun, Davis, Andrew A., Carneiro, Benedito A., Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Giles, Francis J.

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Full title: Clinical outcomes and influencing factors of PD-1/PD-L1 in hepatocellular carcinoma.

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Full title: Adverse events of neoadjuvant combination immunotherapy for resectable cancer patients: a systematic review and meta-analysis.

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The Evolving Landscape of Immunotherapy-Based Combinations for Frontline Treatment of Advanced Renal Cell Carcinoma.

Amin, Asim, Hammers, Hans · 2018

Full title: The Evolving Landscape of Immunotherapy-Based Combinations for Frontline Treatment of Advanced Renal Cell Carcinoma.

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Assessment of Variables Related to the Risk of Severe Adverse Events in Cutaneous Melanoma Patients Treated with Immune Checkpoint Inhibitors.

Trichkova, Kremena Petrova, Görtler, Franziska, Bjørge, Line, Schuster, Cornelia · 2024

Full title: Assessment of Variables Related to the Risk of Severe Adverse Events in Cutaneous Melanoma Patients Treated with Immune Checkpoint Inhibitors.

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Bridging Immune Evasion and Vascular Dynamics for Novel Therapeutic Frontiers in Hepatocellular Carcinoma.

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Full title: Bridging Immune Evasion and Vascular Dynamics for Novel Therapeutic Frontiers in Hepatocellular Carcinoma.

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Immunotherapy of osteosarcoma based on immune microenvironment modulation

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Full title: Immunotherapy of osteosarcoma based on immune microenvironment modulation

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Efficacy of PD-1/PD-L1 inhibitors against pretreated advanced cancer: a systematic review and meta-analysis.

Hu, Hao, Zhu, Qian, Luo, Xian Shi, Yang, Xiong Wen, Wang, Hai Dong, Guo, Chang Ying · 2018

Full title: Efficacy of PD-1/PD-L1 inhibitors against pretreated advanced cancer: a systematic review and meta-analysis.

Authors: Hu, Hao, Zhu, Qian, Luo, Xian Shi, Yang, Xiong Wen, Wang, Hai Dong, Guo, Chang Ying

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Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies.

Wang, Dongxu, Lin, Jianzhen, Yang, Xu, Long, Junyu, Bai, Yi, Yang, Xiaobo, Mao, Yilei, Sang, Xinting, Seery, Samuel, Zhao, Haitao · 2019

Full title: Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies.

Authors: Wang, Dongxu, Lin, Jianzhen, Yang, Xu, Long, Junyu, Bai, Yi, Yang, Xiaobo, Mao, Yilei, Sang, Xinting, Seery, Samuel, Zhao, Haitao

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Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events.

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Full title: Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events.

Authors: Poto, Remo, Troiani, Teresa, Criscuolo, Gjada, Marone, Giancarlo, Ciardiello, Fortunato, Tocchetti, Carlo Gabriele, Varricchi, Gilda

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Full title: Cytoreductive Nephrectomy After Combination of Nivolumab Plus Ipilimumab for Mucinous Tubular and Spindle Cell Carcinoma of the Kidney With Bone Metastases: A Case Report

Authors: Nobuki Furubayashi, K. Taguchi, T. Negishi, A. Miura, Y. Sato, M. Miyoshi, Motonobu Nakamura

DOI: https://doi.org/10.21873/invivo.12732

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer.

Yang, Xueli, Wei, Wujun, Feng, Zhihui, Zhang, Biao, Liu, Yi, Yang, Fei, Zhang, Chong, Ou, Minglin, Liao, Songbai, Hou, Xianliang · 2026

Full title: Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer.

Authors: Yang, Xueli, Wei, Wujun, Feng, Zhihui, Zhang, Biao, Liu, Yi, Yang, Fei, Zhang, Chong, Ou, Minglin, Liao, Songbai, Hou, Xianliang

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Current Knowledge and Perspectives of Immunotherapies for Neuroblastoma.

Mao, Chenkai, Poimenidou, Maria, Craig, Brian T · 2024

Full title: Current Knowledge and Perspectives of Immunotherapies for Neuroblastoma.

Authors: Mao, Chenkai, Poimenidou, Maria, Craig, Brian T

DOI: https://doi.org/10.3390/cancers16162865

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Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ Toxicity After a Single Dose of CTLA-4 Plus PD-1 Blockade: A Case Report.

Matull, Johanna, Livingstone, Elisabeth, Wetter, Axel, Zimmer, Lisa, Zaremba, Anne, Lahner, Harald, Schadendorf, Dirk, Ugurel, Selma · 2020

Authors: Matull, Johanna, Livingstone, Elisabeth, Wetter, Axel, Zimmer, Lisa, Zaremba, Anne, Lahner, Harald, Schadendorf, Dirk, Ugurel, Selma

DOI: https://doi.org/10.3389/fonc.2020.592609

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Current Approaches to Neoadjuvant Immunotherapy in Resectable Non-small Cell Lung Cancer

Parekh, Jay, Parikh, Kaushal, Reuss, Joshua E., Friedlaender, Alex, Addeo, Alfredo · 2023

Full title: Current Approaches to Neoadjuvant Immunotherapy in Resectable Non-small Cell Lung Cancer

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Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.

Seidel, Judith A, Otsuka, Atsushi, Kabashima, Kenji · 2018

Full title: Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.

Authors: Seidel, Judith A, Otsuka, Atsushi, Kabashima, Kenji

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Pretreatment naive T cells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma.

Marks, Kathryne E, Horisberger, Alice, Elahee, Mehreen, Adejoorin, Ifeoluwakiisi A, Ghosh, Nilasha, Postow, Michael, Donlin, Laura, Bass, Anne R, Rao, Deepak A · 2026

Full title: Pretreatment naive T cells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma.

Authors: Marks, Kathryne E, Horisberger, Alice, Elahee, Mehreen, Adejoorin, Ifeoluwakiisi A, Ghosh, Nilasha, Postow, Michael, Donlin, Laura, Bass, Anne R, Rao, Deepak A

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The Uncharted Landscape of Rare Endocrine Immune-Related Adverse Events.

Mytareli, Chrysoula, Ziogas, Dimitrios C, Karampela, Athina, Papalexis, Petros, Siampanopoulou, Vasiliki, Lafioniatis, Alexandros, Benopoulou, Olga, Gogas, Helen, Angelousi, Anna · 2023

Full title: The Uncharted Landscape of Rare Endocrine Immune-Related Adverse Events.

Authors: Mytareli, Chrysoula, Ziogas, Dimitrios C, Karampela, Athina, Papalexis, Petros, Siampanopoulou, Vasiliki, Lafioniatis, Alexandros, Benopoulou, Olga, Gogas, Helen, Angelousi, Anna

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Impaired Heat Shock Protein Expression in Activated T Cells in B-Cell Lymphoma.

Albakova, Zarema, Mangasarova, Yana, Sapozhnikov, Alexander · 2022

Full title: Impaired Heat Shock Protein Expression in Activated T Cells in B-Cell Lymphoma.

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Efficacy and safety of cadonilimab (PD-1/CTLA-4 bispecific) in combination with chemotherapy in anti-PD-1-resistant recurrent or metastatic nasopharyngeal carcinoma: a single-arm, open-label, phase 2 trial.

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PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism.

Dong, Hao, Qi, Yihang, Kong, Xiangyi, Wang, Zhongzhao, Fang, Yi, Wang, Jing · 2022

Full title: PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism.

Authors: Dong, Hao, Qi, Yihang, Kong, Xiangyi, Wang, Zhongzhao, Fang, Yi, Wang, Jing

DOI: https://doi.org/10.3389/fphar.2022.835510

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The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma

Fan, Mengke, Qi, Lili, Zhang, Qi, Wang, Ling · 2021

Full title: The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma

Authors: Fan, Mengke, Qi, Lili, Zhang, Qi, Wang, Ling

DOI: https://doi.org/10.2147/cmar.s285560

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225Actinium-armed antibody targeting CCR8+ regulatory T cells synergizes with immunotherapy to promote tumor rejection in syngeneic colorectal cancer models.

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Full title: 225Actinium-armed antibody targeting CCR8+ regulatory T cells synergizes with immunotherapy to promote tumor rejection in syngeneic colorectal cancer models.

Authors: Frank, Connor, Xiao, Zhiwen, Allen, Kevin J H, Jiao, Rubin, Malo, Mackenzie E, Dadachova, Ekaterina

DOI: https://doi.org/10.3389/fimmu.2025.1662216

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Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers

Full title: Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers

DOI: https://doi.org/10.3390/diseases10030052

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Nivolumab in the treatment of thoracic cancer — new possibilities

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Full title: Nivolumab in the treatment of thoracic cancer — new possibilities

Authors: Knetki‐Wróblewska, Magdalena, Wojas‐Krawczyk, Kamila

DOI: https://doi.org/10.5603/ocp.2022.0033

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Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.

Kirchberger, Michael Constantin, Moreira, Alvaro, Erdmann, Michael, Schuler, Gerold, Heinzerling, Lucie · 2018

Full title: Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.

Authors: Kirchberger, Michael Constantin, Moreira, Alvaro, Erdmann, Michael, Schuler, Gerold, Heinzerling, Lucie

DOI: https://doi.org/10.18632/oncotarget.25627

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Radiation and Immune Checkpoint Inhibitors: Combination Therapy for Treatment of Hepatocellular Carcinoma.

Full title: Radiation and Immune Checkpoint Inhibitors: Combination Therapy for Treatment of Hepatocellular Carcinoma.

DOI: https://doi.org/10.3390/ijms242316773

Paper

Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors

Yang, Ximing, Gao, Miaozhi, Xu, Runshi, Tao, Yangyang, Wang, Luo, Wang, Binya, Zhong, Wenliang, He, Lan, He, Yingchun · 2022

Full title: Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors

Authors: Yang, Ximing, Gao, Miaozhi, Xu, Runshi, Tao, Yangyang, Wang, Luo, Wang, Binya, Zhong, Wenliang, He, Lan, He, Yingchun

DOI: https://doi.org/10.3389/fimmu.2022.969447

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Molecular and Genetic Immune Biomarkers of Primary and Immune-Therapy Induced Hypophysitis: From Laboratories to the Clinical Practice.

Chiloiro, Sabrina, Russo, Filippo, Tartaglione, Tommaso, Capoluongo, Ettore Domenico · 2021

Full title: Molecular and Genetic Immune Biomarkers of Primary and Immune-Therapy Induced Hypophysitis: From Laboratories to the Clinical Practice.

Authors: Chiloiro, Sabrina, Russo, Filippo, Tartaglione, Tommaso, Capoluongo, Ettore Domenico

DOI: https://doi.org/10.3390/jpm11101026

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Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.

Said, Sawsan Sudqi, Ibrahim, Wisam Nabeel · 2024

Full title: Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.

Authors: Said, Sawsan Sudqi, Ibrahim, Wisam Nabeel

DOI: https://doi.org/10.3390/biomedicines12020369

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New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Hirsh, Vera · 2017

Full title: New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Authors: Hirsh, Vera

DOI: https://doi.org/10.2147/ott.s104177

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Data Sheet 1_Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.docx

(10068460), Xinyao Wang, (11716952), Yuli Zhang, (16543), Wei Xie, (135547), Haiying Liu, (22589156), Lianghui Cui, (141118), Min Feng · 2025

Full title: Data Sheet 1_Comparative effectiveness and safety of immunotherapeutic strategies in ovarian cancer: a systematic review and network meta-analysis.docx

Authors: (10068460), Xinyao Wang, (11716952), Yuli Zhang, (16543), Wei Xie, (135547), Haiying Liu, (22589156), Lianghui Cui, (141118), Min Feng

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Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy.

Ren, Xiufang, Guo, Songyi, Guan, Xiaojiao, Kang, Ye, Liu, Jiamei, Yang, Xianghong · 2022

Full title: Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy.

Authors: Ren, Xiufang, Guo, Songyi, Guan, Xiaojiao, Kang, Ye, Liu, Jiamei, Yang, Xianghong

DOI: https://doi.org/10.3389/fimmu.2022.790113

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Immunomodulatory Properties of Immune Checkpoint Inhibitors-More than Boosting T-Cell Responses?

Kuske, Michael, Haist, Maximilian, Jung, Thomas, Grabbe, Stephan, Bros, Matthias · 2022

Full title: Immunomodulatory Properties of Immune Checkpoint Inhibitors-More than Boosting T-Cell Responses?

Authors: Kuske, Michael, Haist, Maximilian, Jung, Thomas, Grabbe, Stephan, Bros, Matthias

DOI: https://doi.org/10.3390/cancers14071710

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Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.

Full title: Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.

DOI: https://doi.org/10.1186/s13046-025-03293-y

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Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.

Liu, Maobai, Cheng, Xitong, Ni, Ruping, Zheng, Bin, Huang, Shunmin, Yang, Jing · 2022

Full title: Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.

Authors: Liu, Maobai, Cheng, Xitong, Ni, Ruping, Zheng, Bin, Huang, Shunmin, Yang, Jing

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Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).

Genoud, Vassilis, Espinoza, Felipe I, Marinari, Eliana, Rochemont, Viviane, Dietrich, Pierre-Yves, McSheehy, Paul, Bachmann, Felix, Lane, Heidi A, Walker, Paul R · 2021

Full title: Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).

Authors: Genoud, Vassilis, Espinoza, Felipe I, Marinari, Eliana, Rochemont, Viviane, Dietrich, Pierre-Yves, McSheehy, Paul, Bachmann, Felix, Lane, Heidi A, Walker, Paul R

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It might be a dead end: immune checkpoint inhibitor therapy in EGFR-mutated NSCLC.

Akao, Ken, Oya, Yuko, Sato, Takaya, Ikeda, Aki, Horiguchi, Tomoya, Goto, Yasuhiro, Hashimoto, Naozumi, Kondo, Masashi, Imaizumi, Kazuyoshi · 2024

Full title: It might be a dead end: immune checkpoint inhibitor therapy in EGFR-mutated NSCLC.

Authors: Akao, Ken, Oya, Yuko, Sato, Takaya, Ikeda, Aki, Horiguchi, Tomoya, Goto, Yasuhiro, Hashimoto, Naozumi, Kondo, Masashi, Imaizumi, Kazuyoshi

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Stoking an anti-liver cancer immune response with cryoablation plus an intratumoral TLR9 agonist and dual checkpoint inhibitors.

Full title: Stoking an anti-liver cancer immune response with cryoablation plus an intratumoral TLR9 agonist and dual checkpoint inhibitors.

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Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma.

Tucker, Matthew D, Rini, Brian I · 2020

Full title: Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma.

Authors: Tucker, Matthew D, Rini, Brian I

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Efficacy and Safety of Programmed Death-1/Programmed Death-Ligand 1 Inhibitor for Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis.

Liao, Pei-Fei, Wang, Ping-Yu, Peng, Tzu-Rong · 2023

Full title: Efficacy and Safety of Programmed Death-1/Programmed Death-Ligand 1 Inhibitor for Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis.

Authors: Liao, Pei-Fei, Wang, Ping-Yu, Peng, Tzu-Rong

DOI: https://doi.org/10.3390/curroncol30110722

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The role of immune checkpoints in cardiovascular disease.

Yousif, Laura I, Tanja, Anniek A, de Boer, Rudolf A, Teske, Arco J, Meijers, Wouter C · 2022

Full title: The role of immune checkpoints in cardiovascular disease.

Authors: Yousif, Laura I, Tanja, Anniek A, de Boer, Rudolf A, Teske, Arco J, Meijers, Wouter C

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Metabolism and senescence in the immune microenvironment of osteosarcoma: focus on new therapeutic strategies

Ying, Hui, Li, Zhiqiang, Li, Meng-Pan, Liu, Wencai · 2023

Full title: Metabolism and senescence in the immune microenvironment of osteosarcoma: focus on new therapeutic strategies

Authors: Ying, Hui, Li, Zhiqiang, Li, Meng-Pan, Liu, Wencai

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Immune Checkpoint Inhibitors' Associated Renal Toxicity: A Series of 12 Cases.

Full title: Immune Checkpoint Inhibitors' Associated Renal Toxicity: A Series of 12 Cases.

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ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

Full title: ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

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TGFβ2 Induces the Soluble Isoform of CTLA-4 - Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma.

Full title: TGFβ2 Induces the Soluble Isoform of CTLA-4 - Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma.

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Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.

Wang, Li, Li, Xiaolin, Zhao, Bin, Mei, Dan, Jiang, Jiandong, Duan, Jingli · 2021

Full title: Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.

Authors: Wang, Li, Li, Xiaolin, Zhao, Bin, Mei, Dan, Jiang, Jiandong, Duan, Jingli

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Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoint blockade

Weihong Tian, Gaofeng Qin, Miaomiao Jia, Wuhao Li, Weili Cai, Hui Wang, Yangjing Zhao, Xuanwen Bao, Wangzhi Wei, Yu Zhang, Qixiang Shao · 2023

Full title: Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoint blockade

Authors: Weihong Tian, Gaofeng Qin, Miaomiao Jia, Wuhao Li, Weili Cai, Hui Wang, Yangjing Zhao, Xuanwen Bao, Wangzhi Wei, Yu Zhang, Qixiang Shao

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Immune checkpoint inhibitors in metastatic melanoma therapy (Review).

Shah, Vedant, Panchal, Viraj, Shah, Abhi, Vyas, Bhavya, Agrawal, Siddharth, Bharadwaj, Sanket · 2024

Full title: Immune checkpoint inhibitors in metastatic melanoma therapy (Review).

Authors: Shah, Vedant, Panchal, Viraj, Shah, Abhi, Vyas, Bhavya, Agrawal, Siddharth, Bharadwaj, Sanket

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Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors.

Xavier, Camila B, Lopes, Carlos Diego H, Awni, Beatriz M, Campos, Eduardo F, Alves, João Pedro B, Camargo, Anamaria A, Guardia, Gabriela D A, Galante, Pedro A F, Jardim, Denis L · 2022

Full title: Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors.

Authors: Xavier, Camila B, Lopes, Carlos Diego H, Awni, Beatriz M, Campos, Eduardo F, Alves, João Pedro B, Camargo, Anamaria A, Guardia, Gabriela D A, Galante, Pedro A F, Jardim, Denis L

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From cold to hot tumors: feasibility of applying therapeutic insights to TNBC.

Yan, Shaozhang, Sun, Xinyue, Wang, Kuanyu · 2025

Full title: From cold to hot tumors: feasibility of applying therapeutic insights to TNBC.

Authors: Yan, Shaozhang, Sun, Xinyue, Wang, Kuanyu

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Case Report: Dual checkpoint inhibition with bevacizumab yields dramatic response in synchronous double primary HCC and ICC with lung metastasis.

He, Yu-Cheng, Dai, Xin-Ye, Lv, Ying-Hao, Yang, Xiao-Juan, Xie, Qing-Yun, Xie, Si-Nan, Cai, Yun-Shi, Gao, Feng-Wei, Lan, Tian · 2025

Full title: Case Report: Dual checkpoint inhibition with bevacizumab yields dramatic response in synchronous double primary HCC and ICC with lung metastasis.

Authors: He, Yu-Cheng, Dai, Xin-Ye, Lv, Ying-Hao, Yang, Xiao-Juan, Xie, Qing-Yun, Xie, Si-Nan, Cai, Yun-Shi, Gao, Feng-Wei, Lan, Tian

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Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.

Peer, Sebastian, Baier, Gottfried, Gruber, Thomas · 2017

Full title: Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.

Authors: Peer, Sebastian, Baier, Gottfried, Gruber, Thomas

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Rationale of Immunotherapy in Hepatocellular Carcinoma and Its Potential Biomarkers.

Tai, David, Choo, Su Pin, Chew, Valerie · 2019

Full title: Rationale of Immunotherapy in Hepatocellular Carcinoma and Its Potential Biomarkers.

Authors: Tai, David, Choo, Su Pin, Chew, Valerie

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Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors.

Lin, Anqi, Huang, Lihaoyun, Jiang, Aimin, Zhu, Lingxuan, Mou, Weiming, Li, Yu, Zhang, Chunyan, Liu, Zaoqu, Zhang, Jian, Cheng, Quan, Wei, Ting, Luo, Peng · 2025

Full title: Microbiota boost immunotherapy? A meta-analysis dives into fecal microbiota transplantation and immune checkpoint inhibitors.

Authors: Lin, Anqi, Huang, Lihaoyun, Jiang, Aimin, Zhu, Lingxuan, Mou, Weiming, Li, Yu, Zhang, Chunyan, Liu, Zaoqu, Zhang, Jian, Cheng, Quan, Wei, Ting, Luo, Peng

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Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Full title: Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

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Severe cardiac events induced by combination immunotherapy in patients with cancer: a meta-analysis.

Valenzuela-Rodriguez, German, Diaz-Arocutipa, Carlos, Collins, Jaime A, Lopez-Fernandez, Teresa, Gomez, Henry L, Hernandez, Adrian V · 2023

Full title: Severe cardiac events induced by combination immunotherapy in patients with cancer: a meta-analysis.

Authors: Valenzuela-Rodriguez, German, Diaz-Arocutipa, Carlos, Collins, Jaime A, Lopez-Fernandez, Teresa, Gomez, Henry L, Hernandez, Adrian V

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Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patients with advanced intrahepatic cholangiocarcinoma.

Huang, Jia-Xin, Liu, Bo, Li, Yu, Li, Xi, Ding, Li-Juan, Wang, Nan-Ya · 2023

Full title: Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patients with advanced intrahepatic cholangiocarcinoma.

Authors: Huang, Jia-Xin, Liu, Bo, Li, Yu, Li, Xi, Ding, Li-Juan, Wang, Nan-Ya

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Decision-Making Biomarkers Guiding Therapeutic Strategies in Hepatocellular Carcinoma: From Prediction to Personalized Care.

Liu, Dongming, Imai, Norihiro · 2025

Full title: Decision-Making Biomarkers Guiding Therapeutic Strategies in Hepatocellular Carcinoma: From Prediction to Personalized Care.

Authors: Liu, Dongming, Imai, Norihiro

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Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient.

Zhang, Er-Lei, Zhang, Zun-Yi, Li, Jian, Huang, Zhi-Yong · 2020

Full title: Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient.

Authors: Zhang, Er-Lei, Zhang, Zun-Yi, Li, Jian, Huang, Zhi-Yong

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Efficacy and Safety of PD-1/PD-L1 Inhibitors in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis

Zhen-Yu Li, Zhen Zhang, Xiaozhong Cao, Yun Feng, Shasha Ren · 2023

Full title: Efficacy and Safety of PD-1/PD-L1 Inhibitors in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis

Authors: Zhen-Yu Li, Zhen Zhang, Xiaozhong Cao, Yun Feng, Shasha Ren

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Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies.

Kato, Daiki, Yaguchi, Tomonori, Iwata, Takashi, Morii, Kenji, Nakagawa, Takayuki, Nishimura, Ryohei, Kawakami, Yutaka · 2017

Full title: Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies.

Authors: Kato, Daiki, Yaguchi, Tomonori, Iwata, Takashi, Morii, Kenji, Nakagawa, Takayuki, Nishimura, Ryohei, Kawakami, Yutaka

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Review of Current and Future Medical Treatments in Head and Neck Squamous Cell Carcinoma

Lee, Aaron M., Weaver, Alice N., Acosta, Phillip, Harris, Lauren, Bowles, Daniel W. · 2024

Full title: Review of Current and Future Medical Treatments in Head and Neck Squamous Cell Carcinoma

Authors: Lee, Aaron M., Weaver, Alice N., Acosta, Phillip, Harris, Lauren, Bowles, Daniel W.

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Recent advances in Merkel cell carcinoma.

Robinson, Caitlin G, Tan, Daniel, Yu, Siegrid S · 2019

Full title: Recent advances in Merkel cell carcinoma.

Authors: Robinson, Caitlin G, Tan, Daniel, Yu, Siegrid S

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The advances in immunotherapy for hepatocellular carcinoma

Zhang, Fan, Li, Yumin · 2020

Full title: The advances in immunotherapy for hepatocellular carcinoma

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Severe Late-Onset Grade III-IV Adverse Events under Immunotherapy: A Retrospective Study of 79 Cases.

L'Orphelin, Jean-Matthieu, Varey, Emilie, Khammari, Amir, Dreno, Brigitte, Dompmartin, Anne · 2021

Full title: Severe Late-Onset Grade III-IV Adverse Events under Immunotherapy: A Retrospective Study of 79 Cases.

Authors: L'Orphelin, Jean-Matthieu, Varey, Emilie, Khammari, Amir, Dreno, Brigitte, Dompmartin, Anne

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Full title: PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.

Authors: Stecher, Carmen, Battin, Claire, Leitner, Judith, Zettl, Markus, Grabmeier-Pfistershammer, Katharina, Höller, Christoph, Zlabinger, Gerhard J, Steinberger, Peter

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Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

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Full title: Drug resistance mechanism and reversal strategy in lung cancer immunotherapy.

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Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retrospective, pharmacovigilance study using the FAERS database.

Fu, Zhiwen, Liu, Jinmei, Zhang, Cong, Hu, Huiping, Li, Shijun, Zhang, Yu, You, Ruxu · 2024

Full title: Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retrospective, pharmacovigilance study using the FAERS database.

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Combination Atezolizumab, Cobimetinib, and Vemurafenib as a Treatment Option in BRAF V600 Mutation-Positive Melanoma: Patient Selection and Perspectives.

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Full title: Combination Atezolizumab, Cobimetinib, and Vemurafenib as a Treatment Option in BRAF V600 Mutation-Positive Melanoma: Patient Selection and Perspectives.

Authors: Dugan, Michelle M, Perez, Matthew C, Karapetyan, Lilit, Zager, Jonathan S

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Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer: Current Status, Recent Advances, and Future Directions

Kamatham, Saivaishnavi, Shahjehan, Faisal, Kasi, Pashtoon Murtaza · 2019

Full title: Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer: Current Status, Recent Advances, and Future Directions

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Advancements in Melanoma Treatment: A Review of PD-1 Inhibitors, T-VEC, mRNA Vaccines, and Tumor-Infiltrating Lymphocyte Therapy in an Evolving Landscape of Immunotherapy.

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Full title: Advancements in Melanoma Treatment: A Review of PD-1 Inhibitors, T-VEC, mRNA Vaccines, and Tumor-Infiltrating Lymphocyte Therapy in an Evolving Landscape of Immunotherapy.

Authors: Mehta, Apoorva, Motavaf, Mateen, Nebo, Ikenna, Luyten, Sophia, Osei-Opare, Kofi D, Gru, Alejandro A

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Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer

Full title: Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer

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What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 4: Experimental Treatments in Pre-Clinical Studies (Cell Lines and Mouse Models).

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Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

Full title: Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

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Full title: Immune-Based Combination Therapies for Advanced Hepatocellular Carcinoma.

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Advanced nanotechnology in enhancing immune checkpoint inhibitors (ICIs) for head and neck cancer therapy.

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Full title: Advanced nanotechnology in enhancing immune checkpoint inhibitors (ICIs) for head and neck cancer therapy.

Authors: Jafari, Zahra, Raoufi, Atieh, Athari, Seyyed Shamsadin, Bahramkiya, Sara, Jafari, Davood

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Update in Immunotherapy for Advanced Non-Small Cell Lung Cancer: Optimizing Treatment Sequencing and Identifying the Best Choices.

Roque, Katia, Ruiz, Rossana, Mas, Luis, Pozza, Daniel Humberto, Vancini, Marina, Silva Júnior, José Antônio, de Mello, Ramon Andrade · 2023

Full title: Update in Immunotherapy for Advanced Non-Small Cell Lung Cancer: Optimizing Treatment Sequencing and Identifying the Best Choices.

Authors: Roque, Katia, Ruiz, Rossana, Mas, Luis, Pozza, Daniel Humberto, Vancini, Marina, Silva Júnior, José Antônio, de Mello, Ramon Andrade

DOI: https://doi.org/10.3390/cancers15184547

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Treatment of intracranial inflammatory myofibroblastic tumor with PD-L1 inhibitor and novel oncolytic adenovirus Ad-TD-nsIL12: a case report and literature review.

Qian, Xiao, Ning, Weihai, Dunmall, Louisa Chard, Qu, Yanming, Wang, Yaohe, Zhang, Hongwei · 2024

Full title: Treatment of intracranial inflammatory myofibroblastic tumor with PD-L1 inhibitor and novel oncolytic adenovirus Ad-TD-nsIL12: a case report and literature review.

Authors: Qian, Xiao, Ning, Weihai, Dunmall, Louisa Chard, Qu, Yanming, Wang, Yaohe, Zhang, Hongwei

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Association between effector-type regulatory T cells and immune checkpoint expression on CD8+ T cells in malignant ascites from epithelial ovarian cancer

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Full title: Association between effector-type regulatory T cells and immune checkpoint expression on CD8+ T cells in malignant ascites from epithelial ovarian cancer

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Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma

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Full title: Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma

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Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis.

van der Leij, Stephanie, Suijkerbuijk, Karijn P M, van den Broek, Medard F M, Valk, Gerlof D, Dankbaar, Jan Willem, van Santen, Hanneke M · 2024

Full title: Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis.

Authors: van der Leij, Stephanie, Suijkerbuijk, Karijn P M, van den Broek, Medard F M, Valk, Gerlof D, Dankbaar, Jan Willem, van Santen, Hanneke M

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The Dual Blockade of the TIGIT and PD-1/PD-L1 Pathway as a New Hope for Ovarian Cancer Patients

Pawłowska, Anna, Skiba, Wiktoria, Suszczyk, Dorota, Kuryło, Weronika, Jakubowicz-Gil, Joanna, Paduch, Roman, Wertel, Iwona · 2022

Full title: The Dual Blockade of the TIGIT and PD-1/PD-L1 Pathway as a New Hope for Ovarian Cancer Patients

Authors: Pawłowska, Anna, Skiba, Wiktoria, Suszczyk, Dorota, Kuryło, Weronika, Jakubowicz-Gil, Joanna, Paduch, Roman, Wertel, Iwona

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DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.

Full title: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.

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Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.

Full title: Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.

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Metabolic Implications of Immune Checkpoint Proteins in Cancer.

Stirling, Elizabeth R, Bronson, Steven M, Mackert, Jessica D, Cook, Katherine L, Triozzi, Pierre L, Soto-Pantoja, David R · 2022

Full title: Metabolic Implications of Immune Checkpoint Proteins in Cancer.

Authors: Stirling, Elizabeth R, Bronson, Steven M, Mackert, Jessica D, Cook, Katherine L, Triozzi, Pierre L, Soto-Pantoja, David R

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Pseudomonas Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation in Preclinical Models.

Leshem, Yasmin, Pastan, Ira · 2019

Full title: Pseudomonas Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation in Preclinical Models.

Authors: Leshem, Yasmin, Pastan, Ira

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Immunotherapeutic Approaches for Treating Hepatocellular Carcinoma.

Shen, Wanying, Chen, Yujie, Lei, Pan, Sheldon, Marisela, Sun, Yutong, Yao, Fan, Ma, Li · 2022

Full title: Immunotherapeutic Approaches for Treating Hepatocellular Carcinoma.

Authors: Shen, Wanying, Chen, Yujie, Lei, Pan, Sheldon, Marisela, Sun, Yutong, Yao, Fan, Ma, Li

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Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

Remón, Jordi, Esteller, Laura, Taus, Álvaro · 2019

Full title: Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

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Schardt, Julian · 2020

Full title: [The use of immune checkpoint inhibitors in routine oncology].

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Neoadjuvant Immunotherapy for Localized Pancreatic Cancer: Challenges and Early Results.

Chick, Robert Connor, Gunderson, Andrew J, Rahman, Shafia, Cloyd, Jordan M · 2023

Full title: Neoadjuvant Immunotherapy for Localized Pancreatic Cancer: Challenges and Early Results.

Authors: Chick, Robert Connor, Gunderson, Andrew J, Rahman, Shafia, Cloyd, Jordan M

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Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status and ethnic origin

Qiu, Junlin, Luo, Shuoming, Yin, Wenfeng, Guo, Keyu, Xiang, Yufei, Li, Xia, Liu, Zhenqi, Zhou, Zhiguang · 2022

Full title: Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status and ethnic origin

Authors: Qiu, Junlin, Luo, Shuoming, Yin, Wenfeng, Guo, Keyu, Xiang, Yufei, Li, Xia, Liu, Zhenqi, Zhou, Zhiguang

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Addressing the Elephant in the Immunotherapy Room: Effector T-Cell Priming versus Depletion of Regulatory T-Cells by Anti-CTLA-4 Therapy.

Hong, Megan M Y, Maleki Vareki, Saman · 2022

Full title: Addressing the Elephant in the Immunotherapy Room: Effector T-Cell Priming versus Depletion of Regulatory T-Cells by Anti-CTLA-4 Therapy.

Authors: Hong, Megan M Y, Maleki Vareki, Saman

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Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer.

Cheng, Weishi, Kang, Kai, Zhao, Ailin, Wu, Yijun · 2024

Full title: Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer.

Authors: Cheng, Weishi, Kang, Kai, Zhao, Ailin, Wu, Yijun

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Immunotherapy and Hepatocellular Cancer: Where Are We Now?

Full title: Immunotherapy and Hepatocellular Cancer: Where Are We Now?

DOI: https://doi.org/10.3390/cancers14184523

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Inhibition of Post-Surgery Tumour Recurrence via a Sprayable Chemoimmunotherapy Gel Releasing PD-L1 Antibody and Platelet-Derived Exosomes

Zhao, Jian, Ye, Hao, Qi, Lu, Wang, Kaiyuan, Chen, Xiaofeng, Song, Jiaxuan, Wang, Helin, Lu, Yutong, Cheng, Maosheng, He, Zhonggui, Zhai, Yinglei, Zhang, Haotian, Sun, Jin · 2021

Full title: Inhibition of Post-Surgery Tumour Recurrence via a Sprayable Chemoimmunotherapy Gel Releasing PD-L1 Antibody and Platelet-Derived Exosomes

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COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

Full title: COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

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Immunotherapy for glioblastoma: the promise of combination strategies.

Bausart, Mathilde, Préat, Véronique, Malfanti, Alessio · 2022

Full title: Immunotherapy for glioblastoma: the promise of combination strategies.

Authors: Bausart, Mathilde, Préat, Véronique, Malfanti, Alessio

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The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ for Immune Checkpoint Inhibitors Response in Metastatic Melanoma Patients: PROTOCOL TRIAL.

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Relationship between single-nucleotide polymorphisms and cancer immunotherapy efficacy and toxicity: a systematic review.

Specchia, Monia, Siringo, Marco, Mazzotti, Eva, Mazzuca, Federica · 2025

Full title: Relationship between single-nucleotide polymorphisms and cancer immunotherapy efficacy and toxicity: a systematic review.

Authors: Specchia, Monia, Siringo, Marco, Mazzotti, Eva, Mazzuca, Federica

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HLA-G and Other Immune Checkpoint Molecules as Targets for Novel Combined Immunotherapies.

Morandi, Fabio, Airoldi, Irma · 2022

Full title: HLA-G and Other Immune Checkpoint Molecules as Targets for Novel Combined Immunotherapies.

Authors: Morandi, Fabio, Airoldi, Irma

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A Comprehensive Review of Immunotherapeutic Modalities in Glioblastoma: Mechanisms, Efficacy, and Safety Considerations †.

Agarwal, Savi, Han, Simon, Lal, Aadi, Vira, Viranshi, Chandla, Anubhav, Mehranpour, Pasha, Yang, Isaac, Wadehra, Madhuri · 2026

Full title: A Comprehensive Review of Immunotherapeutic Modalities in Glioblastoma: Mechanisms, Efficacy, and Safety Considerations †.

Authors: Agarwal, Savi, Han, Simon, Lal, Aadi, Vira, Viranshi, Chandla, Anubhav, Mehranpour, Pasha, Yang, Isaac, Wadehra, Madhuri

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Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach.

Kim, Chang-Gon, Sang, Yun-Beom, Lee, Ji-Hyun, Chon, Hong-Jae · 2021

Full title: Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach.

Authors: Kim, Chang-Gon, Sang, Yun-Beom, Lee, Ji-Hyun, Chon, Hong-Jae

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Response to apatinib and camrelizumab combined treatment in a radioiodine refractory differentiated thyroid cancer patient resistant to prior anti-angiogenic therapy: A case report and literature review.

Li, Jiayi, Zhang, Xin, Mu, Zhuanzhuan, Sun, Di, Sun, Yuqing, Lin, Yansong · 2022

Authors: Li, Jiayi, Zhang, Xin, Mu, Zhuanzhuan, Sun, Di, Sun, Yuqing, Lin, Yansong

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PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma

J. Park, M. Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, W. S. Jang, Won Sik Ham · 2024

Full title: PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma

Authors: J. Park, M. Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, W. S. Jang, Won Sik Ham

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Full title: Untitled

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Dual immune checkpoint blockade in gastroesophageal tumors: never say never

A. Ilhan-Mutlu · 2023

Full title: Dual immune checkpoint blockade in gastroesophageal tumors: never say never

Authors: A. Ilhan-Mutlu

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Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy.

Brilli, L, Danielli, R, Campanile, M, Secchi, C, Ciuoli, C, Calabrò, L, Pilli, T, Cartocci, A, Pacini, F, Di Giacomo, A M, Castagna, M G · 2021

Full title: Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy.

Authors: Brilli, L, Danielli, R, Campanile, M, Secchi, C, Ciuoli, C, Calabrò, L, Pilli, T, Cartocci, A, Pacini, F, Di Giacomo, A M, Castagna, M G

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PD-1/PD-L1 inhibitors for early and middle stage microsatellite high-instability and stable colorectal cancer: a review.

Wu, Huiming, Deng, Min, Xue, Dingwen, Guo, Renkai, Zhang, Chenyu, Gao, Jiaqi, Li, Huiyu · 2024

Full title: PD-1/PD-L1 inhibitors for early and middle stage microsatellite high-instability and stable colorectal cancer: a review.

Authors: Wu, Huiming, Deng, Min, Xue, Dingwen, Guo, Renkai, Zhang, Chenyu, Gao, Jiaqi, Li, Huiyu

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Strategies for treating the cold tumors of cholangiocarcinoma: core concepts and future directions.

Zhang, GuanBo, Li, JinSong, Li, Gang, Zhang, Jie, Yang, Zhi, Yang, Lin, Jiang, ShiJie, Wang, JiaXing · 2024

Full title: Strategies for treating the cold tumors of cholangiocarcinoma: core concepts and future directions.

Authors: Zhang, GuanBo, Li, JinSong, Li, Gang, Zhang, Jie, Yang, Zhi, Yang, Lin, Jiang, ShiJie, Wang, JiaXing

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Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

Full title: Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

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Total T Cell Density and Expression of T Memory Stem Cell Markers are Associated with Better Prognosis in Colon Cancer

Ding, Junli, Wang, Hao, Hou, Rui, Shi, Yuxin, Fan, Honghong, Li, Yuting, Mei, Jie, Zhang, Qinglin, Ruan, Tingyan, Xu, Junying · 2023

Full title: Total T Cell Density and Expression of T Memory Stem Cell Markers are Associated with Better Prognosis in Colon Cancer

Authors: Ding, Junli, Wang, Hao, Hou, Rui, Shi, Yuxin, Fan, Honghong, Li, Yuting, Mei, Jie, Zhang, Qinglin, Ruan, Tingyan, Xu, Junying

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CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy.

Chen, Peifang, Pan, Jianrong, Chen, Ling, Feng, Xiushan · 2025

Full title: CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy.

Authors: Chen, Peifang, Pan, Jianrong, Chen, Ling, Feng, Xiushan

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Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials

Yang, Xing, Yasinjan, Feroza, Du, Yajie, Geng, Huayue, Zhang, Ying, He, Minghua, Guo, Rui, Yang, Lei, Cui, Jiayue, Mu, Dongmei, Liu, Ziling, Wang, Hong · 2023

Full title: Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials

Authors: Yang, Xing, Yasinjan, Feroza, Du, Yajie, Geng, Huayue, Zhang, Ying, He, Minghua, Guo, Rui, Yang, Lei, Cui, Jiayue, Mu, Dongmei, Liu, Ziling, Wang, Hong

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Efficacy and safety of nurulimab+prolgolimab with continued prolgolimab therapy compared to prolgolimab alone as first-line therapy in patients with unresectable or metastatic melanoma: final results of the phase II OBERTON clinical study

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Full title: Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.

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Influence of T Cell Coinhibitory Molecules on CD8+ Recall Responses

Anna B. Morris, Layne E. Adams, M. Ford · 2018

Full title: Influence of T Cell Coinhibitory Molecules on CD8+ Recall Responses

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Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity.

Lesterhuis, W Joost, Salmons, Joanne, Nowak, Anna K, Rozali, Esdy N, Khong, Andrea, Dick, Ian M, Harken, Julie A, Robinson, Bruce W, Lake, Richard A · 2013

Full title: Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity.

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Current Advance of Immune Evasion Mechanisms and Emerging Immunotherapies in Renal Cell Carcinoma.

Jian, Yuli, Yang, Kangkang, Sun, Xiaoxin, Zhao, Jun, Huang, Kai, Aldanakh, Abdullah, Xu, Zhongyang, Wu, Haotian, Xu, Qiwei, Zhang, Lin, Xu, Chunyan, Yang, Deyong, Wang, Shujing · 2021

Full title: Current Advance of Immune Evasion Mechanisms and Emerging Immunotherapies in Renal Cell Carcinoma.

Authors: Jian, Yuli, Yang, Kangkang, Sun, Xiaoxin, Zhao, Jun, Huang, Kai, Aldanakh, Abdullah, Xu, Zhongyang, Wu, Haotian, Xu, Qiwei, Zhang, Lin, Xu, Chunyan, Yang, Deyong, Wang, Shujing

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Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors.

Irabor, Omoruyi Credit, Nelson, Nicolas, Shah, Yash, Niazi, Muneeb Khan, Poiset, Spencer, Storozynsky, Eugene, Singla, Dinender K, Hooper, Douglas Craig, Lu, Bo · 2022

Full title: Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors.

Authors: Irabor, Omoruyi Credit, Nelson, Nicolas, Shah, Yash, Niazi, Muneeb Khan, Poiset, Spencer, Storozynsky, Eugene, Singla, Dinender K, Hooper, Douglas Craig, Lu, Bo

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Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era.

Wang, Shaoli, Chen, Siying, Zhong, Qionglei, Liu, Yan · 2023

Full title: Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era.

Authors: Wang, Shaoli, Chen, Siying, Zhong, Qionglei, Liu, Yan

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Advances in targeted therapy and immunotherapy for melanoma (Review)

Qin, Ziyao, Zheng, Mei · 2023

Full title: Advances in targeted therapy and immunotherapy for melanoma (Review)

Authors: Qin, Ziyao, Zheng, Mei

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CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.

Full title: CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.

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Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Patients With Colon Cancer and to Assist in Immunotherapy.

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Full title: Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Patients With Colon Cancer and to Assist in Immunotherapy.

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Full title: Comparative Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Advanced Cancer: A Systematic Review and Meta-Analysis.

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Full title: PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

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Full title: Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice.

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Full title: Cure the Incurable? Recent Breakthroughs in Immune Checkpoint Blockade for Hepatocellular Carcinoma.

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Full title: Combined treatment of HCC with CTLA-4 inhibitors and PD-1/PD-L1 inhibitors: mechanisms, progress and challenges

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Full title: Rapid Melanoma Death of an Adult Male with Congenital Bathing Trunk Nevus despite Initiation of Combination Immunotherapy

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Full title: Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

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Full title: PD-1/PD-L1 blockades in non-small-cell lung cancer therapy.

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Is There a Role for Immunotherapy in Prostate Cancer?

Full title: Is There a Role for Immunotherapy in Prostate Cancer?

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Full title: A view on drug resistance in cancer

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Full title: Developing combination strategies using PD-1 checkpoint inhibitors to treat cancer.

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Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.

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Full title: Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.

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Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

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Full title: Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

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Immune Checkpoint Inhibitors: A New Opportunity in the Treatment of Ovarian Cancer?

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Full title: Immune Checkpoint Inhibitors: A New Opportunity in the Treatment of Ovarian Cancer?

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CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma

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Full title: CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma

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The Landscape of Immunotherapy in Advanced NSCLC: Driving Beyond PD-1/PD-L1 Inhibitors (CTLA-4, LAG3, IDO, OX40, TIGIT, Vaccines).

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Full title: The Landscape of Immunotherapy in Advanced NSCLC: Driving Beyond PD-1/PD-L1 Inhibitors (CTLA-4, LAG3, IDO, OX40, TIGIT, Vaccines).

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Peng, Xiaoxiao, Zhou, Qing · 2018

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PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy

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Full title: PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy

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Full title: Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies.

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Efficacy and safety of immune checkpoint inhibitors for patients with prostate cancer: a systematic review and meta-analysis.

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Full title: Efficacy and safety of immune checkpoint inhibitors for patients with prostate cancer: a systematic review and meta-analysis.

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A novel mouse model for checkpoint inhibitor-induced adverse events.

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Full title: A novel mouse model for checkpoint inhibitor-induced adverse events.

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Full title: Positive clinical outcomes following therapy with programmed cell death protein 1/programmed cell death ligand 1 inhibitors in neuroendocrine carcinoma of the cervix.

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Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

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The Abscopal Effect in the Era of Checkpoint Inhibitors.

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Full title: The Abscopal Effect in the Era of Checkpoint Inhibitors.

Authors: Kodet, Ondřej, Němejcova, Kristýna, Strnadová, Karolína, Havlínová, Andrea, Dundr, Pavel, Krajsová, Ivana, Štork, Jiří, Smetana, Karel, Lacina, Lukáš

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Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy.

Jin, Xingyi, Qin, Zhigang, Zhao, Hang · 2024

Full title: Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy.

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Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring combined anti-PD-L1/anti-CTLA-4 immunotherapy effects in a murine melanoma model with immunohistochemical validation.

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PD-1 and CTLA-4 serve as major gatekeepers for effector and cytotoxic T-cell potentiation by limiting a CXCL9/10-CXCR3-IFNγ positive feedback loop.

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Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody.

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Full title: Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody.

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Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.

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Full title: Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.

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Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Small Cell Lung Cancer (NSCLC) In Vivo Model.

Full title: Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Small Cell Lung Cancer (NSCLC) In Vivo Model.

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PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil.

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Full title: PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil.

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Table_1_FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: Safety Run-In of Phase II NIVACOR Trial.doc

Full title: Table_1_FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: Safety Run-In of Phase II NIVACOR Trial.doc

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Current Status and Future Direction of Immunotherapy in Hepatocellular Carcinoma: What Do the Data Suggest?

Lee, Hye Won, Cho, Kyung Joo, Park, Jun Yong · 2020

Full title: Current Status and Future Direction of Immunotherapy in Hepatocellular Carcinoma: What Do the Data Suggest?

Authors: Lee, Hye Won, Cho, Kyung Joo, Park, Jun Yong

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Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients.

Troiani, Teresa, Giunta, Emilio Francesco, Tufano, Martina, Vigorito, Vincenza, Arrigo, Paolo D', Argenziano, Giuseppe, Ciardiello, Fortunato, Romano, Maria Fiammetta, Romano, Simona · 2020

Full title: Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients.

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Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities.

Jiao, Ruidi, Luo, Hui, Xu, Wenbo, Ge, Hong · 2019

Full title: Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities.

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Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Full title: Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

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PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease.

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Full title: PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease.

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Full title: A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov.

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Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy.

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Full title: Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy.

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Immune checkpoint inhibitors: breakthroughs in cancer treatment.

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Full title: Immune checkpoint inhibitors: breakthroughs in cancer treatment.

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Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma.

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Full title: Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma.

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Full title: New therapeutics for soft tissue sarcomas: Overview of current immunotherapy and future directions of soft tissue sarcomas

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Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial.

Full title: Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial.

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Immune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies.

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Full title: Immune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies.

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Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression

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Full title: Risk of Cardiac Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-Analysis.

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Full title: Immune Checkpoint Inhibitor Rechallenge in Renal Cell Carcinoma: Current Evidence and Future Directions

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Full title: STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade.

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Full title: Central Nervous System Demyelination Associated With Immune Checkpoint Inhibitors: Review of the Literature.

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Full title: Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoint inhibition in the treatment of pediatric metastatic melanoma.

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Full title: Recent advances in immune checkpoint inhibitors for non-small lung cancer treatment.

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Full title: Immunotherapy for Melanoma: The Significance of Immune Checkpoint Inhibitors for the Treatment of Advanced Melanoma.

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Full title: Cancer immunotherapy: the beginning of the end of cancer?

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Immune Checkpoints and Innovative Therapies in Glioblastoma.

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Full title: Immune Checkpoints and Innovative Therapies in Glioblastoma.

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Full title: Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?

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Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

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Full title: Potential role of immunotherapy in advanced non-small-cell lung cancer.

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Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system.

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Full title: Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system.

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Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC

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Full title: Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC

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[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

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Full title: [Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

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Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities.

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Full title: Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities.

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The Future of Checkpoint Inhibitors in Uveal Melanoma: A Narrative Review.

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Full title: The Future of Checkpoint Inhibitors in Uveal Melanoma: A Narrative Review.

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Nivolumab and Ipilimumab Acting as Tormentors of Advanced Tumors by Unleashing Immune Cells and Associated Collateral Damage.

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Full title: Nivolumab and Ipilimumab Acting as Tormentors of Advanced Tumors by Unleashing Immune Cells and Associated Collateral Damage.

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NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.

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Full title: NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.

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Thyroid Storm and Type 1 Diabetes Mellitus Induced by Combined Ipilimumab and Nivolumab Immunotherapy: A Case Report.

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Full title: Thyroid Storm and Type 1 Diabetes Mellitus Induced by Combined Ipilimumab and Nivolumab Immunotherapy: A Case Report.

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Immunotherapy of melanoma.

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Full title: Immunotherapy of melanoma.

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The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.

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Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma.

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Full title: Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma.

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Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors

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Full title: Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors

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Full title: Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.

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Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect

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Full title: Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect

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Comparison of Efficacy and Safety of Single and Double Immune Checkpoint Inhibitor-Based First-Line Treatments for Advanced Driver-Gene Wild-Type Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.

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Authors: Xu, Qian, Zhang, Xue, Huang, Miao, Dai, Xin, Gao, Jing, Li, Song, Sheng, Lei, Huang, Kai, Wang, Jian, Liu, Lian

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Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors.

Rapoport, Bernardo Leon · 2019

Full title: Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors.

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Anti-CTLA-4 Antibody Might Be Effective Against Non-small Cell Lung Cancer With Large Size Tumor.

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Shiny-MAGEC: A Bayesian R shiny application for meta-analysis of censored adverse events

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Full title: Shiny-MAGEC: A Bayesian R shiny application for meta-analysis of censored adverse events

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Emerging Targets in Clear Cell Renal Cell Carcinoma.

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Full title: Emerging Targets in Clear Cell Renal Cell Carcinoma.

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A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better

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Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma.

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Full title: Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma.

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A Case of Immune-Mediated Pneumonitis Associated With Dual Nivolumab and Ipilimumab Immunotherapy Treatment.

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Full title: A Case of Immune-Mediated Pneumonitis Associated With Dual Nivolumab and Ipilimumab Immunotherapy Treatment.

Authors: Al-Saghir, Tala, Suleiman, Noor, Goodman, Benjamin D, Ferguson, Michael W, Tejwani, Sheela

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A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.

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Full title: A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.

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Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.

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Full title: Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.

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Full title: Targeting immune checkpoints in malignant glioma.

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Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.

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Full title: Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.

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Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.

Full title: Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.

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Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A, Lloyd, Christopher, Dovedi, Simon J, Sansom, David M · 2022

Full title: Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

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S100B and LDH as early prognostic markers for response and overall survival in melanoma patients treated with anti-PD-1 or combined anti-PD-1 plus anti-CTLA-4 antibodies.

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Full title: S100B and LDH as early prognostic markers for response and overall survival in melanoma patients treated with anti-PD-1 or combined anti-PD-1 plus anti-CTLA-4 antibodies.

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Full title: Limitations and potential of immunotherapy in ovarian cancer

Authors: Kumar, Sandeep, Acharya, Sayanti, Karthikeyan, Mahalakshmi, Biswas, Priyobrata, Kumari, Sudha

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Full title: PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.

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Anderson, Ronald, Rapoport, Bernardo L · 2018

Full title: Immune Dysregulation in Cancer Patients Undergoing Immune Checkpoint Inhibitor Treatment and Potential Predictive Strategies for Future Clinical Practice.

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Full title: Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy.

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Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma.

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Full title: Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma.

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Full title: LAG3 immune inhibitors: a novel strategy for melanoma treatment.

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Cutaneous Adverse Events Associated with Immune Checkpoint Inhibitors: A Review Article.

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Full title: Cutaneous Adverse Events Associated with Immune Checkpoint Inhibitors: A Review Article.

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Zhai, Yinghong, Ye, Xiaofei, Hu, Fangyuan, Xu, Jinfang, Guo, Xiaojing, Zhou, Xiang, Zheng, Yi, Zhao, Xinxin, Xu, Xiao, Cao, Yang, He, Jia · 2021

Full title: Metabolic and Nutritional Disorders Following the Administration of Immune Checkpoint Inhibitors: A Pharmacovigilance Study.

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Mucocutaneous adverse events to immune checkpoint inhibitors.

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Full title: Mucocutaneous adverse events to immune checkpoint inhibitors.

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Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

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Full title: Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

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Current Landscape of Immune Checkpoint Inhibitors for Metastatic Urothelial Carcinoma: Is There a Role for Additional T-Cell Blockade?

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Full title: Current Landscape of Immune Checkpoint Inhibitors for Metastatic Urothelial Carcinoma: Is There a Role for Additional T-Cell Blockade?

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Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression

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Full title: Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression

Authors: Mingzhen Zhou, Ziyan Zhou, Lina Hu, Sidong Chen, Fanyan Meng, Jun Chen, Jie Shen

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Type I interferon-mediated tumor immunity and its role in immunotherapy

Yu, Renren, Zhu, Bo, Chen, Degao · 2022

Full title: Type I interferon-mediated tumor immunity and its role in immunotherapy

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Prognostic and predictive value of an immune infiltration signature in diffuse lower-grade gliomas.

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Full title: Prognostic and predictive value of an immune infiltration signature in diffuse lower-grade gliomas.

Authors: Lairong Song, Jiancong Weng, Cheng-bei Li, X. Huo, Huan Li, S. Hao, Zhen Wu, Liang Wang, Da Li, Junting Zhang

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Gastric cancer treatment: recent progress and future perspectives

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Full title: Gastric cancer treatment: recent progress and future perspectives

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Successful treatment of synchronous double lung and colon cancers using immune checkpoint inhibitors.

Matsuoka, Shuichi, Tokuyasu, Hirokazu, Arai, Katsunori, Sakai, Hiromitsu, Esumi, Chika, Yamasaki, Akira · 2026

Full title: Successful treatment of synchronous double lung and colon cancers using immune checkpoint inhibitors.

Authors: Matsuoka, Shuichi, Tokuyasu, Hirokazu, Arai, Katsunori, Sakai, Hiromitsu, Esumi, Chika, Yamasaki, Akira

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Progress in Target-Therapy with Breast Cancer

Yezhou Sun · 2024

Full title: Progress in Target-Therapy with Breast Cancer

Authors: Yezhou Sun

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Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition.

Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph · 2017

Full title: Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition.

Authors: Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph

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Immune Escape and Immune Checkpoint-associated Therapies in the Tumour Microenvironment of Head and Neck Squamous Cell Carcinoma

Qin Yang · 2024

Full title: Immune Escape and Immune Checkpoint-associated Therapies in the Tumour Microenvironment of Head and Neck Squamous Cell Carcinoma

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Advances in immune therapies for the treatment of microsatellite instability‑high/deficient mismatch repair metastatic colorectal cancer (Review)

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Full title: Advances in immune therapies for the treatment of microsatellite instability‑high/deficient mismatch repair metastatic colorectal cancer (Review)

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Biomimetic nanoparticles for tumor immunotherapy

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Full title: Biomimetic nanoparticles for tumor immunotherapy

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Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/- Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets.

Full title: Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/- Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets.

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Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer.

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Full title: Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer.

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A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

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Full title: A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

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Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions.

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Full title: Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions.

Authors: Chipuc, Stefania, Bogdan, Haineala, Serban, Dragos, Badiu, Dumitru Cristinel, Zgura, Anca, Anghel, Rodica

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Severe Immune-Related Pneumonitis With PD-1 Inhibitor After Progression on Previous PD-L1 Inhibitor in Small Cell Lung Cancer: A Case Report and Review of the Literature.

Liang, Xiuju, Guan, Yaping, Zhang, Bicheng, Liang, Jing, Wang, Baocheng, Li, Yan, Wang, Jun · 2019

Full title: Severe Immune-Related Pneumonitis With PD-1 Inhibitor After Progression on Previous PD-L1 Inhibitor in Small Cell Lung Cancer: A Case Report and Review of the Literature.

Authors: Liang, Xiuju, Guan, Yaping, Zhang, Bicheng, Liang, Jing, Wang, Baocheng, Li, Yan, Wang, Jun

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Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma

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Full title: Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma

Authors: Rovers, Sophie, Janssens, Annelies, Raskin, Jo, Pauwels, Patrick, Meerbeeck, Jan P. van, Smits, Evelien, Marcq, Elly

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Case report: Fatal overwhelming post-splenectomy infection in a patient with metastatic angiosarcoma treated with immunotherapy.

Torrado, Carlos, Baysal, Mehmet A, Chakraborty, Abhijit, Norris, Becky L, Khawaja, Fareed, Tsimberidou, Apostolia M · 2024

Full title: Case report: Fatal overwhelming post-splenectomy infection in a patient with metastatic angiosarcoma treated with immunotherapy.

Authors: Torrado, Carlos, Baysal, Mehmet A, Chakraborty, Abhijit, Norris, Becky L, Khawaja, Fareed, Tsimberidou, Apostolia M

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Immunotherapy of thymic epithelial tumors: molecular understandings and clinical perspectives

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Full title: Immunotherapy of thymic epithelial tumors: molecular understandings and clinical perspectives

Authors: Yongqiang Ao, Jian Gao, Shuai Wang, Jiapeng Jiang, J. Deng, Haikun Wang, Bei Xu, Jian-Yong Ding

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Association of PD-L1 positivity with Epstein Barr virus infection and microsatellite instability in gastric carcinomas with lymphoid stroma

Sun Mi Lee, Hyunjoo Oh · 2024

Full title: Association of PD-L1 positivity with Epstein Barr virus infection and microsatellite instability in gastric carcinomas with lymphoid stroma

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Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer.

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Full title: Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer.

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Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.

Full title: Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.

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The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Response in Melanoma Patients.

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Full title: The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Response in Melanoma Patients.

Authors: Tomela, Katarzyna, Pietrzak, Bernadeta, Schmidt, Marcin, Mackiewicz, Andrzej

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The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy.

Dong, Linyinxue, Tian, Xuechen, Zhao, Yunqi, Tu, Haohong, Wong, Aloysius, Yang, Yixin · 2022

Full title: The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy.

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Full title: Overcoming resistance to PD-1/PD-L1 inhibitors in esophageal cancer.

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Li, Wei, Xiong, Hao, Peng, Haiying, Yang, Ting, Fan, Li, Zhang, Yanlin · 2025

Full title: Incidence of pneumonitis with CTLA-4 inhibitors in non-small cell lung cancer: a systematic review and meta-analysis.

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Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy.

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Full title: Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy.

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Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.

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Full title: Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.

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Full title: New PD-L1 inhibitors in non-small cell lung cancer – impact of atezolizumab

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Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC).

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Full title: Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC).

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Full title: Efficacy and safety of PD-1/PD-L1 inhibitors in triple-negative breast cancer: a systematic review and meta-analysis.

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Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours.

Masucci, Giuseppe V, Wersäll, Peter, Kiessling, Rolf, Lundqvist, Andreas, Lewensohn, Rolf · 2012

Full title: Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours.

Authors: Masucci, Giuseppe V, Wersäll, Peter, Kiessling, Rolf, Lundqvist, Andreas, Lewensohn, Rolf

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Small vessel vasculitis and dry gangrene secondary to combined CTLA-4 and PD-1 blockade in malignant mesothelioma

Kefas, Joanna, Harwood, Catherine, Lewis, Myles, Szlosarek, Peter W. · 2022

Full title: Small vessel vasculitis and dry gangrene secondary to combined CTLA-4 and PD-1 blockade in malignant mesothelioma

Authors: Kefas, Joanna, Harwood, Catherine, Lewis, Myles, Szlosarek, Peter W.

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A Novel CTLA-4 affinity peptide for cancer immunotherapy by increasing the integrin αvβ3 targeting.

Zhou, Ying, Song, Shuyi, Yuan, Baomei, Wu, Yahong, Gao, Yanfeng, Wan, Guangming, Li, Guodong · 2022

Full title: A Novel CTLA-4 affinity peptide for cancer immunotherapy by increasing the integrin αvβ3 targeting.

Authors: Zhou, Ying, Song, Shuyi, Yuan, Baomei, Wu, Yahong, Gao, Yanfeng, Wan, Guangming, Li, Guodong

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Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer

T. Veen, A. Kanani, D. Lea, K. Søreide · 2023

Full title: Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer

Authors: T. Veen, A. Kanani, D. Lea, K. Søreide

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Characteristics of Immune Checkpoint Inhibitor-Induced Colitis: A Systematic Review.

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Full title: Characteristics of Immune Checkpoint Inhibitor-Induced Colitis: A Systematic Review.

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Combination Immunotherapies to Overcome Intrinsic Resistance to Checkpoint Blockade in Microsatellite Stable Colorectal Cancer

Kim, Chang Woo, Chon, Hong Jae, Kim, Chan, Kim, Chan, Kim, Chan · 2021

Full title: Combination Immunotherapies to Overcome Intrinsic Resistance to Checkpoint Blockade in Microsatellite Stable Colorectal Cancer

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Chemokines in the Landscape of Cancer Immunotherapy: How They and Their Receptors Can Be Used to Turn Cold Tumors into Hot Ones?

Karin, Nathan · 2021

Full title: Chemokines in the Landscape of Cancer Immunotherapy: How They and Their Receptors Can Be Used to Turn Cold Tumors into Hot Ones?

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The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma

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Full title: The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma

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Current knowledge about immunotherapy resistance for melanoma and potential predictive and prognostic biomarkers.

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Full title: Current knowledge about immunotherapy resistance for melanoma and potential predictive and prognostic biomarkers.

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Rapid onset type 1 diabetes with anti-PD-1 directed therapy.

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Full title: Rapid onset type 1 diabetes with anti-PD-1 directed therapy.

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CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.

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Analysis of synergistic effects of PD-1 inhibitors and CTLA-4 inhibitors in HCC immunotherapy

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Full title: Analysis of synergistic effects of PD-1 inhibitors and CTLA-4 inhibitors in HCC immunotherapy

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Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond

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Ge, Yang, Zhang, Huiyun, Weygant, Nathaniel, Yao, Jiannan · 2021

Full title: Differential Dermatologic Adverse Events Associated With Checkpoint Inhibitor Monotherapy and Combination Therapy: A Meta-Analysis of Randomized Control Trials.

Authors: Ge, Yang, Zhang, Huiyun, Weygant, Nathaniel, Yao, Jiannan

DOI: https://doi.org/10.3389/fphar.2021.640099

Paper

Reprogramming the immunosuppressive breast cancer microenvironment: integrating cellular, metabolic, and stromal targets for rational immunotherapy.

Ma, Chang, Teoh, Hoon Koon, Zhao, Yang, Wang, Yifan, Zhao, Jun, Liu, Yan, Zhao, Chen, Ong, Hooi Tin · 2026

Full title: Reprogramming the immunosuppressive breast cancer microenvironment: integrating cellular, metabolic, and stromal targets for rational immunotherapy.

Authors: Ma, Chang, Teoh, Hoon Koon, Zhao, Yang, Wang, Yifan, Zhao, Jun, Liu, Yan, Zhao, Chen, Ong, Hooi Tin

DOI: https://doi.org/10.3389/fimmu.2026.1760782

Paper

The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice.

Liang, Leilei, Ge, Keli, Zhang, Fengying, Ge, Yinlin · 2018

Full title: The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice.

Authors: Liang, Leilei, Ge, Keli, Zhang, Fengying, Ge, Yinlin

DOI: https://doi.org/10.1186/s11658-018-0122-0

Paper

Medication-associated thyroid eye disease: a review.

Ang, Terence, Almater, Abdullah, Selva, Dinesh · 2026

Full title: Medication-associated thyroid eye disease: a review.

Authors: Ang, Terence, Almater, Abdullah, Selva, Dinesh

DOI: https://doi.org/10.1007/s00417-025-07089-w

Paper

The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.

Yang, Hui, Wang, Kunlun, Wang, Tao, Li, Mengxi, Li, Bingxu, Li, Shenglei, Yuan, Ling · 2020

Full title: The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.

Authors: Yang, Hui, Wang, Kunlun, Wang, Tao, Li, Mengxi, Li, Bingxu, Li, Shenglei, Yuan, Ling

DOI: https://doi.org/10.3389/fonc.2020.00300

Paper

Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma.

Choi, Jaeyeon, Beaino, Wissam, Fecek, Ronald J, Fabian, Kellsye P L, Laymon, Charles M, Kurland, Brenda F, Storkus, Walter J, Anderson, Carolyn J · 2018

Full title: Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma.

Authors: Choi, Jaeyeon, Beaino, Wissam, Fecek, Ronald J, Fabian, Kellsye P L, Laymon, Charles M, Kurland, Brenda F, Storkus, Walter J, Anderson, Carolyn J

DOI: https://doi.org/10.2967/jnumed.118.209510

Paper

The use of immunotherapy in the treatment of melanoma.

Achkar, Tala, Tarhini, Ahmad A · 2017

Full title: The use of immunotherapy in the treatment of melanoma.

Authors: Achkar, Tala, Tarhini, Ahmad A

DOI: https://doi.org/10.1186/s13045-017-0458-3

Paper

Development of therapeutic antibodies for the treatment of diseases

Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung · 2020

Full title: Development of therapeutic antibodies for the treatment of diseases

Authors: Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung

DOI: https://doi.org/10.1186/s12929-019-0592-z

Paper

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

Full title: Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

DOI: https://doi.org/10.1172/jci.insight.145207

Paper

The Risk Ratio of Immune-Related Colitis, Hepatitis, and Pancreatitis in Patients With Solid Tumors Caused by PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Tian, Yuan, Zhang, Zewen, Yang, Xiaowei, Li, Donghua, Zhang, Li, Li, Zhuoqi, Zhang, Shuisheng, Mao, Yantao, Jin, Chenxing, Zhao, Yi · 2020

Full title: The Risk Ratio of Immune-Related Colitis, Hepatitis, and Pancreatitis in Patients With Solid Tumors Caused by PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Authors: Tian, Yuan, Zhang, Zewen, Yang, Xiaowei, Li, Donghua, Zhang, Li, Li, Zhuoqi, Zhang, Shuisheng, Mao, Yantao, Jin, Chenxing, Zhao, Yi

DOI: https://doi.org/10.3389/fonc.2020.00261

Paper

Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.

Sanghera, Chandan, Sanghera, Rohan · 2019

Full title: Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.

Authors: Sanghera, Chandan, Sanghera, Rohan

DOI: https://doi.org/10.7759/cureus.5938

Paper

Real-World Treatment Patterns and Survival in Uveal Melanoma: A Multicenter Cohort Study by the Turkish Oncology Group (TOG)

Full title: Real-World Treatment Patterns and Survival in Uveal Melanoma: A Multicenter Cohort Study by the Turkish Oncology Group (TOG)

DOI: https://doi.org/10.3390/cancers18030394

Paper

Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma.

Park, Robin, Eshrat, Fariha, Al-Jumayli, Mohammed, Saeed, Azhar, Saeed, Anwaar · 2020

Full title: Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma.

Authors: Park, Robin, Eshrat, Fariha, Al-Jumayli, Mohammed, Saeed, Azhar, Saeed, Anwaar

DOI: https://doi.org/10.3390/vaccines8030447

Paper

The efficacy of third generation anti‑HER2 chimeric antigen receptor T�cells in combination with PD1 blockade against malignant glioblastoma cells

Shen, Luxi, Li, Hongzhi, Bin, Shufang, Li, Panyuan, Chen, Jie, Gu, Haihua, Yuan, Weihua · 2019

Full title: The efficacy of third generation anti‑HER2 chimeric antigen receptor T�cells in combination with PD1 blockade against malignant glioblastoma cells

Authors: Shen, Luxi, Li, Hongzhi, Bin, Shufang, Li, Panyuan, Chen, Jie, Gu, Haihua, Yuan, Weihua

DOI: https://doi.org/10.3892/or.2019.7263

Paper

Complete Response Associated With Combination Treatment Regorafenib and Sintilimab in a Sorafenib-refractory Hepatocellular Carcinoma Patient

E. Zhang, Zun-yi Zhang, Lei Zhang, Shuai Xiang, Xiaoping Chen, Zhiyong Huang · 2020

Full title: Complete Response Associated With Combination Treatment Regorafenib and Sintilimab in a Sorafenib-refractory Hepatocellular Carcinoma Patient

Authors: E. Zhang, Zun-yi Zhang, Lei Zhang, Shuai Xiang, Xiaoping Chen, Zhiyong Huang

DOI: https://doi.org/10.21203/rs.3.rs-49286/v1

Paper

Case Report: When dual immune checkpoint blockade strikes back: cadonilimab-induced hypersensitivity in solid tumors - a case series and review.

Song, Ping, Jin, Yuqi, Fu, Linglin, Yang, Fengming, Tan, Yinuo · 2025

Full title: Case Report: When dual immune checkpoint blockade strikes back: cadonilimab-induced hypersensitivity in solid tumors - a case series and review.

Authors: Song, Ping, Jin, Yuqi, Fu, Linglin, Yang, Fengming, Tan, Yinuo

DOI: https://doi.org/10.3389/fimmu.2025.1643279

Paper

Editorial: Unveiling the next generation of cancer immunity & immunotherapy.

Sadasivam, Mohanraj, Muniraj, Nethaji, Thangavel, Chellappagounder · 2025

Full title: Editorial: Unveiling the next generation of cancer immunity & immunotherapy.

Authors: Sadasivam, Mohanraj, Muniraj, Nethaji, Thangavel, Chellappagounder

DOI: https://doi.org/10.3389/fimmu.2025.1769324

Paper

Determination of a prediction model for therapeutic response and prognosis based on chemokine signaling-related genes in stage I–III lung squamous cell carcinoma

Jinzhi Lai, Shiyu Yang, Shu-hua Chu, Tianwen Xu, Jingshan Huang · 2022

Full title: Determination of a prediction model for therapeutic response and prognosis based on chemokine signaling-related genes in stage I–III lung squamous cell carcinoma

Authors: Jinzhi Lai, Shiyu Yang, Shu-hua Chu, Tianwen Xu, Jingshan Huang

DOI: https://doi.org/10.3389/fgene.2022.921837

Paper

The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

Full title: The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

DOI: https://doi.org/10.1186/s12967-022-03406-7

Paper

Immunotherapy Updates in Advanced Hepatocellular Carcinoma

Singh, Amisha, Beechinor, Ryan J., Huynh, Jasmine C., Li, Daneng, Dayyani, Farshid, Valerin, Jennifer Brooke, Hendifar, Andrew, Gong, Jun, Cho, May · 2021

Full title: Immunotherapy Updates in Advanced Hepatocellular Carcinoma

Authors: Singh, Amisha, Beechinor, Ryan J., Huynh, Jasmine C., Li, Daneng, Dayyani, Farshid, Valerin, Jennifer Brooke, Hendifar, Andrew, Gong, Jun, Cho, May

DOI: https://doi.org/10.3390/cancers13092164

Paper

Immune Checkpoint Blockade - How Does It Work in Brain Metastases?

Lorger, Mihaela, Andreou, Tereza, Fife, Christopher, James, Fiona · 2019

Full title: Immune Checkpoint Blockade - How Does It Work in Brain Metastases?

Authors: Lorger, Mihaela, Andreou, Tereza, Fife, Christopher, James, Fiona

DOI: https://doi.org/10.3389/fnmol.2019.00282

Paper

Mapping endocrine toxicity spectrum of immune checkpoint inhibitors: a disproportionality analysis using the WHO adverse drug reaction database, VigiBase.

Bai, Xuefeng, Lin, Xiahong, Zheng, Kainan, Chen, Xiaoyu, Wu, Xiaohong, Huang, Yinqiong, Zhuang, Yong · 2020

Full title: Mapping endocrine toxicity spectrum of immune checkpoint inhibitors: a disproportionality analysis using the WHO adverse drug reaction database, VigiBase.

Authors: Bai, Xuefeng, Lin, Xiahong, Zheng, Kainan, Chen, Xiaoyu, Wu, Xiaohong, Huang, Yinqiong, Zhuang, Yong

DOI: https://doi.org/10.1007/s12020-020-02355-9

Paper

Lung Cancer Immunotherapy: Beyond Common Immune Checkpoints Inhibitors.

Catalano, Martina, Shabani, Sonia, Venturini, Jacopo, Ottanelli, Carlotta, Voltolini, Luca, Roviello, Giandomenico · 2022

Full title: Lung Cancer Immunotherapy: Beyond Common Immune Checkpoints Inhibitors.

Authors: Catalano, Martina, Shabani, Sonia, Venturini, Jacopo, Ottanelli, Carlotta, Voltolini, Luca, Roviello, Giandomenico

DOI: https://doi.org/10.3390/cancers14246145

Paper

Combination Immunotherapy Strategies in Breast Cancer

Chun, Brie, Page, David B., McArthur, Heather L. · 2019

Full title: Combination Immunotherapy Strategies in Breast Cancer

Authors: Chun, Brie, Page, David B., McArthur, Heather L.

DOI: https://doi.org/10.1007/s12609-019-00333-3

Paper

Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medicare Advantage patients.

Gunturu, Krishna S, Pham, Timothy T, Shambhu, Sonali, Fisch, Michael J, Barron, John J, Debono, David · 2022

Full title: Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medicare Advantage patients.

Authors: Gunturu, Krishna S, Pham, Timothy T, Shambhu, Sonali, Fisch, Michael J, Barron, John J, Debono, David

DOI: https://doi.org/10.1007/s00520-022-06826-9

Paper

Next-Generation Immunotherapies to Improve Anticancer Immunity.

Shi, Yaoyao, Tomczak, Katarzyna, Li, June, Ochieng, Joshua K, Lee, Younghee, Haymaker, Cara · 2020

Full title: Next-Generation Immunotherapies to Improve Anticancer Immunity.

Authors: Shi, Yaoyao, Tomczak, Katarzyna, Li, June, Ochieng, Joshua K, Lee, Younghee, Haymaker, Cara

DOI: https://doi.org/10.3389/fphar.2020.566401

Paper

Mechanisms of resistance to immune checkpoint inhibitors

Jenkins, Russell W., Barbie, David A., Flaherty, Keith T. · 2018

Full title: Mechanisms of resistance to immune checkpoint inhibitors

Authors: Jenkins, Russell W., Barbie, David A., Flaherty, Keith T.

DOI: https://doi.org/10.1038/bjc.2017.434

Paper

Endocrine Side Effects in Patients Treated with Immune Checkpoint Inhibitors: A Narrative Review.

Profili, Nicia I, Castelli, Roberto, Gidaro, Antonio, Merella, Alessandro, Manetti, Roberto, Palmieri, Giuseppe, Maioli, Margherita, Delitala, Alessandro P · 2023

Full title: Endocrine Side Effects in Patients Treated with Immune Checkpoint Inhibitors: A Narrative Review.

Authors: Profili, Nicia I, Castelli, Roberto, Gidaro, Antonio, Merella, Alessandro, Manetti, Roberto, Palmieri, Giuseppe, Maioli, Margherita, Delitala, Alessandro P

DOI: https://doi.org/10.3390/jcm12155161

Paper

Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.

Turbitt, William J, Orlandella, Rachael M, Gibson, Justin T, Peterson, Courtney M, Norian, Lyse A · 2020

Full title: Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.

Authors: Turbitt, William J, Orlandella, Rachael M, Gibson, Justin T, Peterson, Courtney M, Norian, Lyse A

DOI: https://doi.org/10.21873/anticanres.14555

Paper

Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series.

Arora, Puja, Talamo, Laura, Dillon, Patrick, Gentzler, Ryan D, Millard, Trish, Salerno, Michael, Slingluff, Craig L, Gaughan, Elizabeth M · 2020

Full title: Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series.

Authors: Arora, Puja, Talamo, Laura, Dillon, Patrick, Gentzler, Ryan D, Millard, Trish, Salerno, Michael, Slingluff, Craig L, Gaughan, Elizabeth M

DOI: https://doi.org/10.1186/s40959-020-00076-6

Paper

Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.

Full title: Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.

DOI: https://doi.org/10.1371/journal.pone.0191926

Paper

Immune checkpoint-targeted antibodies: a room for dose and schedule optimization?

Maritaz, Christophe, Broutin, Sophie, Chaput, Nathalie, Marabelle, Aurélien, Paci, Angelo · 2022

Full title: Immune checkpoint-targeted antibodies: a room for dose and schedule optimization?

Authors: Maritaz, Christophe, Broutin, Sophie, Chaput, Nathalie, Marabelle, Aurélien, Paci, Angelo

DOI: https://doi.org/10.1186/s13045-021-01182-3

Paper

Immune-related cardiovascular toxicities of PD-1/PD-L1 inhibitors in solid tumors: an updated systematic review and meta-analysis.

Zhang, Chi, Wei, Fengtao, Ma, Wenhan, Zhang, Jingbo · 2024

Full title: Immune-related cardiovascular toxicities of PD-1/PD-L1 inhibitors in solid tumors: an updated systematic review and meta-analysis.

Authors: Zhang, Chi, Wei, Fengtao, Ma, Wenhan, Zhang, Jingbo

DOI: https://doi.org/10.3389/fimmu.2024.1255825

Paper

Comparative Risk of Renal Adverse Events in Patients Receiving Immune Checkpoint Inhibitors: A Bayesian Network Meta-Analysis.

Liu, Kang, Qin, Zhongke, Xu, Xueqiang, Li, Ting, Ge, Yifei, Mao, Huijuan, Xing, Changying · 2021

Full title: Comparative Risk of Renal Adverse Events in Patients Receiving Immune Checkpoint Inhibitors: A Bayesian Network Meta-Analysis.

Authors: Liu, Kang, Qin, Zhongke, Xu, Xueqiang, Li, Ting, Ge, Yifei, Mao, Huijuan, Xing, Changying

DOI: https://doi.org/10.3389/fonc.2021.662731

Paper

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Full title: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

DOI: https://doi.org/10.1038/s41586-024-07943-7

Paper

Exploiting Human NK Cells in Tumor Therapy.

Vacca, Paola, Pietra, Gabriella, Tumino, Nicola, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo · 2019

Full title: Exploiting Human NK Cells in Tumor Therapy.

Authors: Vacca, Paola, Pietra, Gabriella, Tumino, Nicola, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo

DOI: https://doi.org/10.3389/fimmu.2019.03013

Paper

Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma

Full title: Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma

DOI: https://doi.org/10.1186/s40364-021-00334-4

Paper

T-cell-based Immunotherapies for Haematological Cancers, Part A: A SWOT Analysis of Immune Checkpoint Inhibitors (ICIs) and Bispecific T-Cell Engagers (BiTEs).

Rallis, Kathrine S, Hillyar, Christopher R T, Sideris, Michail, Davies, Jeff K · 2021

Full title: T-cell-based Immunotherapies for Haematological Cancers, Part A: A SWOT Analysis of Immune Checkpoint Inhibitors (ICIs) and Bispecific T-Cell Engagers (BiTEs).

Authors: Rallis, Kathrine S, Hillyar, Christopher R T, Sideris, Michail, Davies, Jeff K

DOI: https://doi.org/10.21873/anticanres.14870

Paper

Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.

Maines, Lynn W, Keller, Staci N, Smith, Ryan A, Schrecengost, Randy S, Smith, Charles D · 2024

Full title: Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.

Authors: Maines, Lynn W, Keller, Staci N, Smith, Ryan A, Schrecengost, Randy S, Smith, Charles D

DOI: https://doi.org/10.3390/cancers16091779

Paper

Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies.

Golay, Josée, Andrea, Alain E · 2020

Full title: Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies.

Authors: Golay, Josée, Andrea, Alain E

DOI: https://doi.org/10.3390/antib9020017

Paper

Results from a Meta-analysis of Combination of PD-1/PD-L1 and CTLA-4 Inhibitors in Malignant Cancer Patients: Does PD-L1 Matter?

Feng, Yuqian, Jin, Huimin, Guo, Kaibo, Xiang, Yuying, Zhang, Yiting, Du, Wurong, Shen, Minhe, Ruan, Shanming · 2021

Full title: Results from a Meta-analysis of Combination of PD-1/PD-L1 and CTLA-4 Inhibitors in Malignant Cancer Patients: Does PD-L1 Matter?

Authors: Feng, Yuqian, Jin, Huimin, Guo, Kaibo, Xiang, Yuying, Zhang, Yiting, Du, Wurong, Shen, Minhe, Ruan, Shanming

DOI: https://doi.org/10.3389/fphar.2021.572845

Paper

Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging.

Tran, Renee L, Liang, Xiaofei, de la Cerda, Jorge, Schuler, F William, Pagel, Mark D · 2025

Full title: Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging.

Authors: Tran, Renee L, Liang, Xiaofei, de la Cerda, Jorge, Schuler, F William, Pagel, Mark D

DOI: https://doi.org/10.1038/s41598-025-05930-0

Paper

Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report.

Zhao, Jiayu, Li, Xiaoxiao, Sun, Xiaoyuan, Xiao, Ruoxi, Xue, Juan, Sui, Kexin, Liu, Zimin · 2025

Full title: Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report.

Authors: Zhao, Jiayu, Li, Xiaoxiao, Sun, Xiaoyuan, Xiao, Ruoxi, Xue, Juan, Sui, Kexin, Liu, Zimin

DOI: https://doi.org/10.3389/fimmu.2025.1533700

Paper

Success of Checkpoint Blockade Paves the Way for Novel Immune Therapy in Malignant Pleural Mesothelioma.

Rondon, Lizbeth, Fu, Roberto, Patel, Manish R · 2023

Full title: Success of Checkpoint Blockade Paves the Way for Novel Immune Therapy in Malignant Pleural Mesothelioma.

Authors: Rondon, Lizbeth, Fu, Roberto, Patel, Manish R

DOI: https://doi.org/10.3390/cancers15112940

Paper

Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors

Salewski, Inken, Kuntoff, Steffen, Kuemmel, Andreas, Feldtmann, Rico, Felix, Stephan B., Henze, Larissa, Junghanß, Christian, Maletzki, Claudia · 2021

Full title: Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors

Authors: Salewski, Inken, Kuntoff, Steffen, Kuemmel, Andreas, Feldtmann, Rico, Felix, Stephan B., Henze, Larissa, Junghanß, Christian, Maletzki, Claudia

DOI: https://doi.org/10.1007/s00262-021-02933-4

Paper

Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report.

Meyers, D E, Hill, W F, Suo, A, Jimenez-Zepeda, V, Cheng, T, Nixon, N A · 2018

Full title: Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report.

Authors: Meyers, D E, Hill, W F, Suo, A, Jimenez-Zepeda, V, Cheng, T, Nixon, N A

DOI: https://doi.org/10.1186/s40164-018-0098-5

Paper

Immune Checkpoint Inhibitors in the Treatment of HCC.

Full title: Immune Checkpoint Inhibitors in the Treatment of HCC.

DOI: https://doi.org/10.3389/fonc.2020.601240

Paper

The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

John, Peter, Pulanco, Marc C., Galbo, Phillip M., Yao, Wei, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing · 2022

Full title: The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

Authors: John, Peter, Pulanco, Marc C., Galbo, Phillip M., Yao, Wei, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing

DOI: https://doi.org/10.1038/s41467-022-30143-8

Paper

Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

Liu, Shaokun, Wang, Ru, Fang, Jugao · 2024

Full title: Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

Authors: Liu, Shaokun, Wang, Ru, Fang, Jugao

DOI: https://doi.org/10.1007/s12672-024-00870-z

Paper

Unveiling the Etiopathogenic Spectrum of Hypophysitis: A Narrative Review.

Full title: Unveiling the Etiopathogenic Spectrum of Hypophysitis: A Narrative Review.

DOI: https://doi.org/10.3390/jpm13081210

Paper

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Kroon, Paula, Gadiot, Jules, Peeters, Marlies, Gasparini, Alessia, Deken, Marcel A, Yagita, Hideo, Verheij, Marcel, Borst, Jannie, Blank, Christian U, Verbrugge, Inge · 2016

Full title: Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Authors: Kroon, Paula, Gadiot, Jules, Peeters, Marlies, Gasparini, Alessia, Deken, Marcel A, Yagita, Hideo, Verheij, Marcel, Borst, Jannie, Blank, Christian U, Verbrugge, Inge

DOI: https://doi.org/10.1007/s00262-016-1843-4

Paper

Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET

Full title: Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET

DOI: https://doi.org/10.7150/thno.35989

Paper

Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.

McGinnis, Gwendolyn J, Friedman, David, Young, Kristina H, Torres, Eileen Ruth S, Thomas, Charles R, Gough, Michael J, Raber, Jacob · 2017

Full title: Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.

Authors: McGinnis, Gwendolyn J, Friedman, David, Young, Kristina H, Torres, Eileen Ruth S, Thomas, Charles R, Gough, Michael J, Raber, Jacob

DOI: https://doi.org/10.18632/oncotarget.13551

Paper

Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.

Haibe, Yolla, El Husseini, Ziad, El Sayed, Rola, Shamseddine, Ali · 2020

Full title: Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.

Authors: Haibe, Yolla, El Husseini, Ziad, El Sayed, Rola, Shamseddine, Ali

DOI: https://doi.org/10.3390/ijms21176176

Paper

[Clinical practice and mechanism of endocrinological adverse events associated with immune checkpoint inhibitors].

Iwama, Shintaro, Arima, Hiroshi · 2017

Full title: [Clinical practice and mechanism of endocrinological adverse events associated with immune checkpoint inhibitors].

Authors: Iwama, Shintaro, Arima, Hiroshi

DOI: https://doi.org/10.2177/jsci.40.90

Paper

Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma

Xuejie Yang, Xiaoqian Yu, H. Nie, Wenying Jiang, Jian-hua Zhou, Chunlin Ou, Xiaoyun He · 2023

Full title: Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma

Authors: Xuejie Yang, Xiaoqian Yu, H. Nie, Wenying Jiang, Jian-hua Zhou, Chunlin Ou, Xiaoyun He

DOI: https://doi.org/10.7150/jca.87590

Paper

Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.

Tao, Hua, Qian, Pudong, Wang, Feijiang, Yu, Hongliang, Guo, Yesong · 2017

Full title: Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.

Authors: Tao, Hua, Qian, Pudong, Wang, Feijiang, Yu, Hongliang, Guo, Yesong

DOI: https://doi.org/10.3727/096504017X14900505020895

Paper

Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors.

Chong, Pei Pei, Rubin, Joshua B, Abdullah, Maha, Conforti, Fabio, Klein, Sabra L, Liu, Wanli · 2022

Full title: Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors.

Authors: Chong, Pei Pei, Rubin, Joshua B, Abdullah, Maha, Conforti, Fabio, Klein, Sabra L, Liu, Wanli

DOI: https://doi.org/10.3389/fimmu.2022.941254

Paper

CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis.

Ma, Bing, Kamle, Suchitra, Akosman, Bedia, Khan, Hina, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A · 2022

Full title: CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis.

Authors: Ma, Bing, Kamle, Suchitra, Akosman, Bedia, Khan, Hina, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A

DOI: https://doi.org/10.3389/fimmu.2022.1056397

Paper

Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors.

Zoi, Vasiliki, Galani, Vasiliki, Sioka, Chrissa, Alexiou, Georgios A, Kyritsis, Athanassios P · 2025

Full title: Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors.

Authors: Zoi, Vasiliki, Galani, Vasiliki, Sioka, Chrissa, Alexiou, Georgios A, Kyritsis, Athanassios P

DOI: https://doi.org/10.3390/cancers17233777

Paper

The multidimensional regulatory network of the PD-1/PD-L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyu Lai, Lu Qi, Zhixuan Lin, Zhong Li · 2025

Authors: Haoyu Lai, Lu Qi, Zhixuan Lin, Zhong Li

DOI: https://doi.org/10.3892/or.2025.9021

Paper

Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors.

Oh, Chang-Myung, Chon, Hong Jae, Kim, Chan · 2020

Full title: Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors.

Authors: Oh, Chang-Myung, Chon, Hong Jae, Kim, Chan

DOI: https://doi.org/10.3390/ijms21207743

Paper

Immunotherapy in Breast Cancer: the New Frontier.

Hu, Zishuo I, McArthur, Heather L · 2018

Full title: Immunotherapy in Breast Cancer: the New Frontier.

Authors: Hu, Zishuo I, McArthur, Heather L

DOI: https://doi.org/10.1007/s12609-018-0274-y

Paper

Hyaluronidase Enhances Targeting of Hydrogel-Encapsulated Anti-CTLA-4 to Tumor Draining Lymph Nodes and Improves Anti-Tumor Efficacy.

Harui, Airi, Roth, Michael D · 2022

Full title: Hyaluronidase Enhances Targeting of Hydrogel-Encapsulated Anti-CTLA-4 to Tumor Draining Lymph Nodes and Improves Anti-Tumor Efficacy.

Authors: Harui, Airi, Roth, Michael D

DOI: https://doi.org/10.3390/gels8050284

Paper

Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy

Mandy van Gulijk, Floris Dammeijer, J. Aerts, H. Vroman · 2018

Full title: Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy

Authors: Mandy van Gulijk, Floris Dammeijer, J. Aerts, H. Vroman

DOI: https://doi.org/10.3389/fimmu.2018.02759

Paper

Treatment-Related Adverse Events of Combination Immune Checkpoint Inhibitors: Systematic Review and Meta-Analysis.

Park, Robin, Lopes, Laercio, Cristancho, Cagney R, Riano, Ivy M, Saeed, Anwaar · 2020

Full title: Treatment-Related Adverse Events of Combination Immune Checkpoint Inhibitors: Systematic Review and Meta-Analysis.

Authors: Park, Robin, Lopes, Laercio, Cristancho, Cagney R, Riano, Ivy M, Saeed, Anwaar

DOI: https://doi.org/10.3389/fonc.2020.00258

Paper

High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model.

Full title: High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model.

DOI: https://doi.org/10.3390/cancers14092087

Paper

PD-1/PD-L1 Inhibitor - Related Adverse Events and Their Management in Breast Cancer.

Lei, Chuqi, Kong, Xiangyi, Li, Yuan, Yang, Huaiyu, Zhang, Ke, Wang, Zhongzhao, Chang, Hu, Xuan, Lixue · 2024

Full title: PD-1/PD-L1 Inhibitor - Related Adverse Events and Their Management in Breast Cancer.

Authors: Lei, Chuqi, Kong, Xiangyi, Li, Yuan, Yang, Huaiyu, Zhang, Ke, Wang, Zhongzhao, Chang, Hu, Xuan, Lixue

DOI: https://doi.org/10.7150/jca.85433

Paper

Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.

Zhang, Zhen, Rafei-Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, Rebecca, Huzly, Daniela, Pinato, David J, Thimme, Robert, Meiss, Frank, Bengsch, Bertram · 2022

Full title: Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity.

Authors: Zhang, Zhen, Rafei-Shamsabadi, David, Lehr, Saskia, Buettner, Nico, Diehl, Rebecca, Huzly, Daniela, Pinato, David J, Thimme, Robert, Meiss, Frank, Bengsch, Bertram

DOI: https://doi.org/10.1186/s12967-022-03755-3

Paper

Immune Blockade Inhibition in Breast Cancer.

Voutsadakis, Ioannis A · 2016

Full title: Immune Blockade Inhibition in Breast Cancer.

Authors: Voutsadakis, Ioannis A

DOI: https://doi.org/10.21873/anticanres.11145

Paper

Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.

Lim, Sung Won, Ahn, Myung-Ju · 2019

Full title: Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.

Authors: Lim, Sung Won, Ahn, Myung-Ju

DOI: https://doi.org/10.3904/kjim.2018.179

Paper

Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma

Sadagopan, Narayanan, He, Aiwu Ruth · 2024

Full title: Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma

Authors: Sadagopan, Narayanan, He, Aiwu Ruth

DOI: https://doi.org/10.3390/ijms25021259

Paper

- **Authors:** Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir - **Year:** 2025 - **Journal:** Tumor Discovery - **Source:** openalex

Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir · 2025

Full title: - **Authors:** Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir - **Year:** 2025 - **Journal:** Tumor Discovery - **Source:** openalex

Authors: Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir

DOI: https://doi.org/10.36922/td025320076

Paper

Immunotherapy in Advanced Lung Cancer Treatment

A. Grigorescu · 2018

Full title: Immunotherapy in Advanced Lung Cancer Treatment

Authors: A. Grigorescu

DOI: https://doi.org/10.5772/intechopen.77005

Paper

Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review.

Kovács, Szonja Anna, Győrffy, Balázs · 2022

Full title: Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review.

Authors: Kovács, Szonja Anna, Győrffy, Balázs

DOI: https://doi.org/10.1186/s12967-022-03409-4

Paper

Clinical benefits of PD-1/PD-L1 inhibitors in patients with metastatic colorectal cancer: a systematic review and meta-analysis.

Zhang, Xiao, Yang, Zhengyang, An, Yongbo, Liu, Yishan, Wei, Qi, Xu, Fengming, Yao, Hongwei, Zhang, Zhongtao · 2022

Full title: Clinical benefits of PD-1/PD-L1 inhibitors in patients with metastatic colorectal cancer: a systematic review and meta-analysis.

Authors: Zhang, Xiao, Yang, Zhengyang, An, Yongbo, Liu, Yishan, Wei, Qi, Xu, Fengming, Yao, Hongwei, Zhang, Zhongtao

DOI: https://doi.org/10.1186/s12957-022-02549-7

Paper

Immunological Agents Used in Cancer Treatment.

Simsek, Melih, Tekin, Salim Basol, Bilici, Mehmet · 2019

Full title: Immunological Agents Used in Cancer Treatment.

Authors: Simsek, Melih, Tekin, Salim Basol, Bilici, Mehmet

DOI: https://doi.org/10.5152/eurasianjmed.2018.18194

Paper

Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response.

Wang, Dong-Rui, Wu, Xian-Lin, Sun, Ying-Li · 2022

Full title: Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response.

Authors: Wang, Dong-Rui, Wu, Xian-Lin, Sun, Ying-Li

DOI: https://doi.org/10.1038/s41392-022-01136-2

Paper

CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.

Yang, Yuanzheng, Zhou, Yifan, Wang, Jian, Zhou, You, Watowich, Stephanie S, Kleinerman, Eugenie S · 2024

Full title: CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.

Authors: Yang, Yuanzheng, Zhou, Yifan, Wang, Jian, Zhou, You, Watowich, Stephanie S, Kleinerman, Eugenie S

DOI: https://doi.org/10.3390/cancers16193251

Paper

Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives.

Shen, Ke-Yu, Zhu, Ying, Xie, Sun-Zhe, Qin, Lun-Xiu · 2024

Full title: Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives.

Authors: Shen, Ke-Yu, Zhu, Ying, Xie, Sun-Zhe, Qin, Lun-Xiu

DOI: https://doi.org/10.1186/s13045-024-01549-2

Paper

Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni · 2021

Full title: Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Authors: Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni

DOI: https://doi.org/10.3390/ijms22126309

Paper

Successful Response to Nivolumab Plus Ipilimumab Therapy in a Hemodialysis Patient With Metastatic Renal Cell Carcinoma.

Masuda, Hiroshi, Mikami, Kosuke, Otsuka, Kotaro, Hou, Kyokusin, Suyama, Takahito, Araki, Kazuhiro, Kojima, Satoko, Naya, Yukio · 2021

Full title: Successful Response to Nivolumab Plus Ipilimumab Therapy in a Hemodialysis Patient With Metastatic Renal Cell Carcinoma.

Authors: Masuda, Hiroshi, Mikami, Kosuke, Otsuka, Kotaro, Hou, Kyokusin, Suyama, Takahito, Araki, Kazuhiro, Kojima, Satoko, Naya, Yukio

DOI: https://doi.org/10.21873/cdp.10028

Paper

Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells.

Motoshima, Takanobu, Komohara, Yoshihiro, Horlad, Hasita, Takeuchi, Ario, Maeda, Yoshihiro, Tanoue, Kenichiro, Kawano, Yoshiaki, Harada, Mamoru, Takeya, Motohiro, Eto, Masatoshi · 2015

Full title: Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells.

Authors: Motoshima, Takanobu, Komohara, Yoshihiro, Horlad, Hasita, Takeuchi, Ario, Maeda, Yoshihiro, Tanoue, Kenichiro, Kawano, Yoshiaki, Harada, Mamoru, Takeya, Motohiro, Eto, Masatoshi

DOI: https://doi.org/10.3892/or.2015.3893

Paper

The Continuum of Thyroid Disorders Related to Immune Checkpoint Inhibitors: Still Many Pending Queries.

Deligiorgi, Maria V, Sagredou, Sofia, Vakkas, Lampros, Trafalis, Dimitrios T · 2021

Full title: The Continuum of Thyroid Disorders Related to Immune Checkpoint Inhibitors: Still Many Pending Queries.

Authors: Deligiorgi, Maria V, Sagredou, Sofia, Vakkas, Lampros, Trafalis, Dimitrios T

DOI: https://doi.org/10.3390/cancers13215277

Paper

Efficacy and safety of PD-1/PD-L1 inhibitors in the treatment of recurrent and refractory ovarian cancer: A systematic review and a meta-analysis.

Zeng, Siyuan, Liu, Daju, Yu, Yongai, Zou, Lei, Jin, Xianyu, Liu, Bing, Liu, Lifeng · 2023

Full title: Efficacy and safety of PD-1/PD-L1 inhibitors in the treatment of recurrent and refractory ovarian cancer: A systematic review and a meta-analysis.

Authors: Zeng, Siyuan, Liu, Daju, Yu, Yongai, Zou, Lei, Jin, Xianyu, Liu, Bing, Liu, Lifeng

DOI: https://doi.org/10.3389/fphar.2023.1111061

Paper

Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Sundström, E., Huang, Xueting, Wiemer, Andrew J. · 2025

Full title: Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Authors: Sundström, E., Huang, Xueting, Wiemer, Andrew J.

DOI: https://doi.org/10.1007/s00262-025-04128-7

Paper

Neoadjuvant PD-1/PD-L1 combined with CTLA-4 inhibitors for solid malignancies: a systematic review and meta-analysis.

Huang, Shuang, Zheng, Gang, Yang, Kai · 2023

Full title: Neoadjuvant PD-1/PD-L1 combined with CTLA-4 inhibitors for solid malignancies: a systematic review and meta-analysis.

Authors: Huang, Shuang, Zheng, Gang, Yang, Kai

DOI: https://doi.org/10.1186/s12957-023-03212-5

Paper

How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Full title: How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

DOI: https://doi.org/10.3390/cancers13184719

Paper

Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina · 2021

Full title: Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

Authors: Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina

DOI: https://doi.org/10.1007/s00259-020-05054-9

Paper

ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.

Full title: ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.

DOI: https://doi.org/10.3390/jcm9072060

Paper

Efficacy and safety of immune checkpoint inhibitors combined with chemotherapy in patients with extensive-stage small cell lung cancer: a systematic review and meta-analysis of randomized controlled trials.

Chen, Chunlan, Tian, Peng, Zhong, Jiangshan, Fan, Xianming · 2023

Authors: Chen, Chunlan, Tian, Peng, Zhong, Jiangshan, Fan, Xianming

DOI: https://doi.org/10.3389/fonc.2023.1151769

Paper

Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

DOI: https://doi.org/10.1007/s00262-023-03541-0

Paper

Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade.

Buchbinder, Elizabeth, Hodi, F Stephen · 2015

Full title: Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade.

Authors: Buchbinder, Elizabeth, Hodi, F Stephen

DOI: https://doi.org/10.1172/JCI80012

Paper

Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion

C. Bruss, K. Kellner, V. Albert, James A. Hutchinson, S. Seitz, O. Ortmann, G. Brockhoff, A. Wege · 2023

Full title: Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion

Authors: C. Bruss, K. Kellner, V. Albert, James A. Hutchinson, S. Seitz, O. Ortmann, G. Brockhoff, A. Wege

DOI: https://doi.org/10.3390/cancers15092615

Paper

TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

Liu, Heng-Jia, Lizotte, Patrick H, Du, Heng, Speranza, Maria C, Lam, Hilaire C, Vaughan, Spencer, Alesi, Nicola, Wong, Kwok-Kin, Freeman, Gordon J, Sharpe, Arlene H, Henske, Elizabeth P · 2018

Full title: TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

Authors: Liu, Heng-Jia, Lizotte, Patrick H, Du, Heng, Speranza, Maria C, Lam, Hilaire C, Vaughan, Spencer, Alesi, Nicola, Wong, Kwok-Kin, Freeman, Gordon J, Sharpe, Arlene H, Henske, Elizabeth P

DOI: https://doi.org/10.1172/jci.insight.98674

Paper

Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.

Hu, Guangqiang, Li, Zeng, Chen, Yongji, Liao, Hong, Zhou, Shukui · 2025

Full title: Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.

Authors: Hu, Guangqiang, Li, Zeng, Chen, Yongji, Liao, Hong, Zhou, Shukui

DOI: https://doi.org/10.3389/fimmu.2025.1664587

Paper

The role of immune checkpoint inhibitors in prostate cancer.

Surdacki, Gabriel, Szudy-Szczyrek, Aneta, Gorący, Aneta, Chyl-Surdacka, Katarzyna, Hus, Marek · 2019

Full title: The role of immune checkpoint inhibitors in prostate cancer.

Authors: Surdacki, Gabriel, Szudy-Szczyrek, Aneta, Gorący, Aneta, Chyl-Surdacka, Katarzyna, Hus, Marek

DOI: https://doi.org/10.26444/aaem/96331

Paper

CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade.

Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal · 2021

Full title: CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade.

Authors: Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal

DOI: https://doi.org/10.3390/cancers13081935

Paper

Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways

Feng Wang, Ayse Ece Cali Daylan, L. Deng, Jihua Yang, Janaki Sharma, C. Su, Shenduo Li, X. Zang, B. Halmos, A. Borczuk, Haiying Cheng · 2023

Full title: Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways

Authors: Feng Wang, Ayse Ece Cali Daylan, L. Deng, Jihua Yang, Janaki Sharma, C. Su, Shenduo Li, X. Zang, B. Halmos, A. Borczuk, Haiying Cheng

DOI: https://doi.org/10.3390/cancers15133372

Paper

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Full title: DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

DOI: https://doi.org/10.1038/ncomms15618

Paper

The future of combination immunotherapy in oesophageal adenocarcinoma.

Davern, Maria, Donlon, Noel E · 2023

Full title: The future of combination immunotherapy in oesophageal adenocarcinoma.

Authors: Davern, Maria, Donlon, Noel E

DOI: https://doi.org/10.3389/fimmu.2023.1217132

Paper

Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model

Suarez, Eloah Rabello, Chang, De-Kuan, Sun, Jiusong, Sui, Jianhua, Freeman, Gordon J., Signoretti, Sabina, Zhu, Quan, Marasco, Wayne A. · 2016

Full title: Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model

Authors: Suarez, Eloah Rabello, Chang, De-Kuan, Sun, Jiusong, Sui, Jianhua, Freeman, Gordon J., Signoretti, Sabina, Zhu, Quan, Marasco, Wayne A.

DOI: https://doi.org/10.18632/oncotarget.9114

Paper

A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H. · 2020

Full title: A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Authors: Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H.

DOI: https://doi.org/10.3747/co.27.5223

Paper

Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model.

Full title: Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model.

DOI: https://doi.org/10.1371/journal.pone.0092572

Paper

Clinical observation of immune checkpoint inhibitors in the treatment of advanced pancreatic cancer: a real-world study in Chinese cohort.

Sun, Danyang, Ma, Junxun, Wang, Jinliang, Zhang, Fan, Wang, Lijie, Zhang, Sujie, Chen, Guangying, Li, Xiaoyan, Du, Wushuang, Cui, Pengfei, Hu, Yi · 2018

Full title: Clinical observation of immune checkpoint inhibitors in the treatment of advanced pancreatic cancer: a real-world study in Chinese cohort.

Authors: Sun, Danyang, Ma, Junxun, Wang, Jinliang, Zhang, Fan, Wang, Lijie, Zhang, Sujie, Chen, Guangying, Li, Xiaoyan, Du, Wushuang, Cui, Pengfei, Hu, Yi

DOI: https://doi.org/10.2147/TCRM.S173041

Paper

Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics.

Zhang, Ying, Garofano, Francesca, Wu, Xiaolong, Schmid, Matthias, Krawitz, Peter, Essler, Markus, Schmidt-Wolf, Ingo G H · 2020

Full title: Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics.

Authors: Zhang, Ying, Garofano, Francesca, Wu, Xiaolong, Schmid, Matthias, Krawitz, Peter, Essler, Markus, Schmidt-Wolf, Ingo G H

DOI: https://doi.org/10.1007/s10637-020-00952-z

Paper

Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund · 2021

Full title: Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Authors: Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund

DOI: https://doi.org/10.3390/cancers13061430

Thesis

Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Ascierto, PA; Atkins, M; Bifulco, C et al. · 2021

Full title: Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

DOI: https://hdl.handle.net/11343/262597

Thesis

A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors

van Not, Olivier J; Wind, Thijs T; Ismail, Rawa K et al. · 2023

Full title: A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors

DOI: https://dspace.library.uu.nl/handle/1874/449336

Thesis

Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma

Verheijden, Rik J.; Burgers, Femke H.; Janssen, Josephine C. et al. · 2024

Full title: Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma

DOI: https://dspace.library.uu.nl/handle/1874/453162

Thesis

Economic evaluation of single versus combination immuno-oncology therapies: Application of a novel modelling approach in metastatic melanoma

Gibson, EJ; Begum, N; Koblbauer, I et al. · 2021

Full title: Economic evaluation of single versus combination immuno-oncology therapies: Application of a novel modelling approach in metastatic melanoma

Authors: Gibson, EJ; Begum, N; Koblbauer, I; Dranitsaris, G; Liew, D; McEwan, P; Yuan, Y; Juarez-Garcia, A; Tyas, D; Pritchard, C

DOI: https://hdl.handle.net/11343/271942

Thesis

Spotlight on landmark oncology trials: the latest evidence and novel trial designs

Earl, Helena; Molica, Stefano; Rutkowski, Piotr · 2017

Full title: Spotlight on landmark oncology trials: the latest evidence and novel trial designs

Authors: Earl, Helena; Molica, Stefano; Rutkowski, Piotr

DOI: https://www.repository.cam.ac.uk/handle/1810/264598

Thesis

Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies

Van Not, Olivier J; van den Eertwegh, Alfons J M; Haanen, John B et al. · 2023

Full title: Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies

DOI: https://dspace.library.uu.nl/handle/1874/448987

Thesis

The Epstein-Barr Virus Hacks Immune Checkpoints: Evidence and Consequences for Lymphoproliferative Disorders and Cancers

Biggi, Alison Felipe Bordini [UNESP]; de Oliveira, Deilson Elgui [UNESP] · 2022

Full title: The Epstein-Barr Virus Hacks Immune Checkpoints: Evidence and Consequences for Lymphoproliferative Disorders and Cancers

Authors: Biggi, Alison Felipe Bordini [UNESP]; de Oliveira, Deilson Elgui [UNESP]

DOI: http://dx.doi.org/10.3390/biom12030397

Thesis

Role Of Il-27 And Tcr Stimulation In Inhibitory Receptor Expression

Delong, Jonathan Howard · 2023

Full title: Role Of Il-27 And Tcr Stimulation In Inhibitory Receptor Expression

Authors: Delong, Jonathan Howard

DOI: https://repository.upenn.edu/handle/20.500.14332/30093

Thesis

Immunotherapy for Renal Cancer: Sequencing and Combinations

Stewart, GD; De Santis, M; Escudier, B et al. · 2017

Full title: Immunotherapy for Renal Cancer: Sequencing and Combinations

Authors: Stewart, GD; De Santis, M; Escudier, B; Powles, T; Sonpavde, G

DOI: https://www.repository.cam.ac.uk/handle/1810/265376

Thesis

The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive et al. · 2024

Full title: The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Authors: Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive; Fox, Bernard; Ibrahim, Ramy; Sharma, Padmanee; Allison, James P.; Maio, Michele

DOI: https://dspace.library.uu.nl/handle/1874/454126

Thesis

Podnl1 methylation serves as a prognostic biomarker and associates with immune cell infiltration and immune checkpoint blockade response in lower-grade glioma

Noor, H; https://orcid.org/0000-0001-8887-8122; Zaman, A et al. · 2021

Full title: Podnl1 methylation serves as a prognostic biomarker and associates with immune cell infiltration and immune checkpoint blockade response in lower-grade glioma

Authors: Noor, H ; https://orcid.org/0000-0001-8887-8122; Zaman, A ; https://orcid.org/0000-0002-2492-5281; Teo, C; Sughrue, ME

DOI: http://hdl.handle.net/1959.4/104080

Thesis

Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Sandin, Linda · 2013

Full title: Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Authors: Sandin, Linda

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210080

Thesis

CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

Fietz, Simon; Zarbl, Romina; Niebel, Dennis et al. · 2020

Full title: CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

DOI: https://mediatum.ub.tum.de/1624233

Thesis

Two distinct clinical patterns of checkpoint inhibitor-induced thyroid dysfunction

Olsson-Brown, Anna; Lord, Rosemary; Sacco, Joseph et al. · 2020

Full title: Two distinct clinical patterns of checkpoint inhibitor-induced thyroid dysfunction

Authors: Olsson-Brown, Anna; Lord, Rosemary; Sacco, Joseph; Wagg, Jonathan; Coles, Mark; Pirmohamed, Munir

DOI: https://livrepository.liverpool.ac.uk/3100413/1/Two%20distinct%20clinical%20patterns%20of%20checkpoint%20inhibitor-induced%20thyroid%20dysfunction.pdf

Thesis

Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma

Lelliott, EJ; McArthur, GA; Oliaro, J et al. · 2021

Full title: Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma

Authors: Lelliott, EJ; McArthur, GA; Oliaro, J; Sheppard, KE

DOI: https://hdl.handle.net/11343/278309

Thesis

Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders

Brown, LJ; Weppler, A; Bhave, P et al. · 2021

Full title: Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders

Authors: Brown, LJ; Weppler, A; Bhave, P; Allayous, C; Patrinely, JR; Ott, P; Sandhu, S; Haydon, A; Lebbe, C; Johnson, DB; Long, GV; Menzies, AA; Carlino, MS

DOI: https://hdl.handle.net/11343/280628

Thesis

Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Nguyen, Kim Bich; Spranger, Stefani · 2021

Full title: Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Authors: Nguyen, Kim Bich; Spranger, Stefani

DOI: https://hdl.handle.net/1721.1/135977

Thesis

Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma

Schuiveling, M; Tonk, E H J; Verheijden, R J et al. · 2021

Full title: Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma

Authors: Schuiveling, M; Tonk, E H J; Verheijden, R J; Suijkerbuijk, K P M

DOI: https://dspace.library.uu.nl/handle/1874/440555

Thesis

Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Regev, Aviv · 2020

Full title: Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Authors: Regev, Aviv

DOI: https://hdl.handle.net/1721.1/125051

Thesis

Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity

Hammond, Sean; Olsson-Brown, Anna; Grice, Sophie et al. · 2022

Full title: Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity

Thesis

Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials

Verheijden, Rik J; de Groot, Jolien S; Fabriek, Babs O et al. · 2024

Full title: Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials

Authors: Verheijden, Rik J; de Groot, Jolien S; Fabriek, Babs O; Hew, Miki N; May, Anne M; Suijkerbuijk, Karijn P M

DOI: https://dspace.library.uu.nl/handle/1874/458069

Thesis

Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Guillén, Noelia Carolina Talavera [UNESP] · 2023

Full title: Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Authors: Guillén, Noelia Carolina Talavera [UNESP]

DOI: http://hdl.handle.net/11449/239302

Thesis

Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Duchnowska, R; Peksa, R; Radecka, B et al. · 2021

Full title: Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

DOI: https://hdl.handle.net/11343/260579

Thesis

Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Oliver, AJ; Keam, SP; von Scheidt, B et al. · 2020

Full title: Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Authors: Oliver, AJ; Keam, SP; von Scheidt, B; Zanker, DJ; Harrison, AJ; Tantalo, DGM; Darcy, PK; Kershaw, MH; Slaney, CY

DOI: https://hdl.handle.net/11343/247618

Thesis

Emerging role of PTEN loss in evasion of the immune response to tumours

Vidotto, Thiago; Melo, Camila Morais; Castelli, Erick [UNESP] et al. · 2020

Full title: Emerging role of PTEN loss in evasion of the immune response to tumours

Authors: Vidotto, Thiago; Melo, Camila Morais; Castelli, Erick [UNESP]; Koti, Madhuri; Reis, Rodolfo Borges dos; Squire, Jeremy A.

DOI: http://dx.doi.org/10.1038/s41416-020-0834-6

Thesis

Mechanisms of response and resistance to anti-PD-1 immunotherapy

Edwards, Jarem · 2022

Full title: Mechanisms of response and resistance to anti-PD-1 immunotherapy

Authors: Edwards, Jarem

DOI: https://hdl.handle.net/2123/29470

Thesis

Immune checkpoints as gatekeepers of CD8+ T cell differentiation

Carrera Haro, Maria Augusta · 2019

Full title: Immune checkpoints as gatekeepers of CD8+ T cell differentiation

Authors: Carrera Haro, Maria Augusta

DOI: http://jhir.library.jhu.edu/handle/1774.2/61568

Thesis

Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients

Biewenga, Maaike; van der Kooij, Monique K; Wouters, Michel W J M et al. · 2021

Full title: Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients

DOI: https://dspace.library.uu.nl/handle/1874/442328

Thesis

Effektivität von neuen systemtherapeutischen Optionen bei Patienten mit metastasiertem Nierenzellkarzinom

Sandin, Per Niklas · 2025

Full title: Effektivität von neuen systemtherapeutischen Optionen bei Patienten mit metastasiertem Nierenzellkarzinom

Authors: Sandin, Per Niklas

DOI: https://refubium.fu-berlin.de/handle/fub188/47981

Thesis

Withdrawal of β-catenin in an Inducible Genetically Engineered Mouse Model Restores T Cell Infiltration but Not Checkpoint Blockade Efficacy

Cabanov, Alexandra · 2024

Full title: Withdrawal of β-catenin in an Inducible Genetically Engineered Mouse Model Restores T Cell Infiltration but Not Checkpoint Blockade Efficacy

Authors: Cabanov, Alexandra

DOI: https://knowledge.uchicago.edu/record/12428/files/Cabanov_uchicago_0330D_17485.pdf

Thesis

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis et al. · 2017

Full title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

DOI: http://hdl.handle.net/1721.1/109826

Thesis

Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study

van Not, Olivier J; de Meza, Melissa M; van den Eertwegh, Alfons J M et al. · 2022

Full title: Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study

DOI: https://dspace.library.uu.nl/handle/1874/446113

Thesis

The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Kuchroo, Juhi · 2020

Full title: The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Authors: Kuchroo, Juhi

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365910

Thesis

Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Iyer, Nivedha Srikanth · 2024

Full title: Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Authors: Iyer, Nivedha Srikanth

DOI: https://escholarship.org/uc/item/5m579278

Thesis

**Institution:** University of Melbourne **Date:** 2021-05-11T01:43:51Z

Dorff, T; Rettig, M; Machiels, J-P et al. · 2021

Full title: **Institution:** University of Melbourne **Date:** 2021-05-11T01:43:51Z

Authors: Dorff, T; Rettig, M; Machiels, J-P; Lolkema, M; Autio, K; Greil, R; Rottey, S; Adra, N; Salvati, M; Poon, S; Tan, D; Jurida, G; Kouros-Mehr, H; Fizazi, K; Tran, B; Horvath, L

DOI: https://hdl.handle.net/11343/273969

Thesis

A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Conduit, C; Davis, ID; Goh, JC et al. · 2024

Full title: A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

DOI: https://hdl.handle.net/11343/339980

Thesis

Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Klein, O; Kee, D; Gao, B et al. · 2022

Full title: Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Authors: Klein, O; Kee, D; Gao, B; Markman, B; Da Gama Duarte, J; Quigley, L; Jackett, L; Linklater, R; Strickland, A; Scott, C; Mileshkin, L; Palmer, J; Carlino, M; Behren, A; Cebon, J

DOI: https://hdl.handle.net/11343/296391

Thesis

Tissue-specific tumor microenvironments influence responses to immunotherapies

Oliver, AJ; Davey, AS; Keam, SP et al. · 2020

Full title: Tissue-specific tumor microenvironments influence responses to immunotherapies

Authors: Oliver, AJ; Davey, AS; Keam, SP; Mardiana, S; Chan, JD; von Scheidt, B; Beavis, PA; House, IG; Van Audernaerde, JRM; Darcy, PK; Kershaw, MH; Slaney, CY

DOI: https://hdl.handle.net/11343/247124

Thesis

An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Bottai, G; Raschioni, C; Losurdo, A et al. · 2020

Full title: An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Authors: Bottai, G; Raschioni, C; Losurdo, A; Di Tommaso, L; Tinterri, C; Torrisi, R; Reis-Filho, JS; Roncalli, M; Sotiriou, C; Santoro, A; Mantovani, A; Loi, S; Santarpia, L

DOI: https://hdl.handle.net/11343/257795

Thesis

Mechanisms Of Lung Cancer Hyper-Progression Promoted By Pd-1 Immune Checkpoint Blockade

Martinez-Usatorre, A.; Kadioglu, E.; Cianciaruso, C. et al. · 2021

Full title: Mechanisms Of Lung Cancer Hyper-Progression Promoted By Pd-1 Immune Checkpoint Blockade

Authors: Martinez-Usatorre, A.; Kadioglu, E.; Cianciaruso, C.; Torchia, B.; Faget, J.; Meylan, E.; Schmittnaegel, M.; Keklikoglou, I.; De Palma, M.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/176286

Thesis

Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Wang, M; Zadeh, S; Pizzolla, A et al. · 2022

Full title: Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Authors: Wang, M; Zadeh, S; Pizzolla, A; Thia, K; Gyorki, DE; McArthur, GA; Scolyer, RA; Long, G; Wilmott, JS; Andrews, MC; Au-Yeung, G; Weppler, A; Sandhu, S; Trapani, JA; Davis, MJ; Neeson, PJ

DOI: https://hdl.handle.net/11343/307216

Thesis

Biomarkers in immuno-oncology : from melanoma to other cancer types, from tissue to liquid biopsy, from late stage to early stage disease

Meireson, Annabel · 2022

Full title: Biomarkers in immuno-oncology : from melanoma to other cancer types, from tissue to liquid biopsy, from late stage to early stage disease

Authors: Meireson, Annabel

DOI: https://biblio.ugent.be/publication/8742933

Thesis

First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update

Reck, M; Ciuleanu, TE; Cobo, M et al. · 2022

Full title: First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update

DOI: https://hdl.handle.net/11343/308764

Thesis

Rare Immune-Related Adverse Events (irAEs): Approach to Diagnosis and Management

Javaid, A; Bennett, C; Rao, A et al. · 2025

Full title: Rare Immune-Related Adverse Events (irAEs): Approach to Diagnosis and Management

Authors: Javaid, A; Bennett, C; Rao, A; Spain, L

DOI: https://hdl.handle.net/11343/358266

Thesis

Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma

Leek, Lindsay V M; Notohardjo, Jessica C L; de Joode, Karlijn et al. · 2024

Full title: Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma

DOI: https://dspace.library.uu.nl/handle/1874/452909

Thesis

Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

Laia Gorchs (18664483) · 2022

Full title: Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

Authors: Laia Gorchs (18664483)

DOI: oai:figshare.com:article/26906092

Thesis

LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma

Klümper, N; Ralser, DJ; Bawden, EG et al. · 2021

Full title: LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma

Authors: Klümper, N; Ralser, DJ; Bawden, EG; Landsberg, J; Zarbl, R; Kristiansen, G; Toma, M; Ritter, M; Hölzel, M; Ellinger, J; Dietrich, D

DOI: https://hdl.handle.net/11343/277676

Thesis

Survival in early phase immuno-oncology trials: Development and validation of a prognostic index

Day, D; Guo, C; Kanjanapan, Y et al. · 2021

Full title: Survival in early phase immuno-oncology trials: Development and validation of a prognostic index

Authors: Day, D; Guo, C; Kanjanapan, Y; Tran, B; Spreafico, A; Joshua, AM; Wang, L; Abdul Razak, AR; Leighl, NB; Hansen, AR; Butler, MO; Siu, LL; Desai, J; Bedard, PL

DOI: https://hdl.handle.net/11343/271795

Thesis

Exploring the Interplay of Oncolytic Measles Vaccines with the Cancer-Immunity Cycle

Pidelaserra Martí, Gemma · 2024

Full title: Exploring the Interplay of Oncolytic Measles Vaccines with the Cancer-Immunity Cycle

Authors: Pidelaserra Martí, Gemma

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34509/1/2023-10-19_PhD_Thesis_GemmaPidelaserraMarti.pdf

Thesis

Sex-Based Differences in Treatment with Immune Checkpoint Inhibition and Targeted Therapy for Advanced Melanoma: A Nationwide Cohort Study

van der Kooij, Monique K; Dekkers, Olaf M; Aarts, Maureen J B et al. · 2021

Full title: Sex-Based Differences in Treatment with Immune Checkpoint Inhibition and Targeted Therapy for Advanced Melanoma: A Nationwide Cohort Study

DOI: https://dspace.library.uu.nl/handle/1874/443821

Thesis

Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Ferris, Robert L; Spanos, William C; Leidner, Rom et al. · 2021

Full title: Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

DOI: https://dspace.library.uu.nl/handle/1874/442886

Thesis

Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M et al. · 2022

Full title: Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

DOI: https://dspace.library.uu.nl/handle/1874/447350

Thesis

Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Wein, L; Luen, SJ; Savas, P et al. · 2020

Full title: Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Authors: Wein, L; Luen, SJ; Savas, P; Salgado, R; Loi, S

DOI: https://hdl.handle.net/11343/255249

Thesis

Single cell landscape of innate and adaptive immunity in metastatic melanoma treated with immunotherapy

Fu, Ruiwen · 2022

Full title: Single cell landscape of innate and adaptive immunity in metastatic melanoma treated with immunotherapy

Authors: Fu, Ruiwen

DOI: https://hdl.handle.net/1721.1/144938

Thesis

T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

Evans, Rebecca A · 2023

Full title: T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

Authors: Evans, Rebecca A

DOI: https://repository.upenn.edu/handle/20.500.14332/28546

Thesis

TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes

Trivedi, P; Jhala, G; De George, DJ et al. · 2024

Full title: TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes

Authors: Trivedi, P; Jhala, G; De George, DJ; Chiu, C; Selck, C; Ge, T; Catterall, T; Elkerbout, L; Boon, L; Joller, N; Kay, TW; Thomas, HE; Krishnamurthy, B

DOI: https://hdl.handle.net/11343/353275

Thesis

What is the ideal endpoint in early-stage immunotherapy neoadjuvant trials in lung cancer?

Cameron, Robert B; Hines, Jacobi B; Torri, Valter et al. · 2023

Full title: What is the ideal endpoint in early-stage immunotherapy neoadjuvant trials in lung cancer?

Authors: Cameron, Robert B; Hines, Jacobi B; Torri, Valter; Porcu, Luca; Donington, Jessica; Bestvina, Christine M; Vokes, Everett; Dolezal, James M; Esposito, Alessandra; Garassino, Marina C

DOI: https://www.repository.cam.ac.uk/handle/1810/357602

Thesis

Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas

Sanghvi, Khwab · 2023

Full title: Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas

Authors: Sanghvi, Khwab

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/33640/1/Dissertation_Khwab%20Sanghvi_2023.pdf

Thesis

FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma

Zhou, L; Barros E Silva, MJ; Hsiao, E et al. · 2025

Full title: FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma

DOI: https://hdl.handle.net/11343/360308

Thesis

817 Activated osteoarthritis following immune checkpoint inhibitor treatment: an observational study

Reid, P; Liew, D; Akruwala, R et al. · 2022

Full title: 817 Activated osteoarthritis following immune checkpoint inhibitor treatment: an observational study

Authors: Reid, P; Liew, D; Akruwala, R; Bass, A; Chan, K

DOI: https://hdl.handle.net/11343/307941

Thesis

The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

DOI: https://www.repository.cam.ac.uk/handle/1810/327626

Thesis

Regulation of the Inflamed Tumor Phenotype in Melanoma Immunotherapy

Lo, Jennifer · 2017

Full title: Regulation of the Inflamed Tumor Phenotype in Melanoma Immunotherapy

Authors: Lo, Jennifer

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493467

Thesis

63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Reck, M; Regan, M; Carbone, DP et al. · 2024

Authors: Reck, M; Regan, M; Carbone, DP; Lu, S; John, T; Penrod, J; Li, J; Yuan, Y; Mahmood, J; Lee, A; Eccles, L; Ray, S; Paz-Ares, L

DOI: https://hdl.handle.net/11343/351905

Thesis

Dual CD47 and PD-L1 blockade elicits anti-tumor immunity by intratumoral CD8+ T cells

Christo, SN; Mcdonald, KM; Burn, TN et al. · 2025

Full title: Dual CD47 and PD-L1 blockade elicits anti-tumor immunity by intratumoral CD8+ T cells

Authors: Christo, SN; Mcdonald, KM; Burn, TN; Kurd, N; Stanfield, J; Kaneda, MM; Seelige, R; Dillon, CP; Fisher, TS; Baaten, B; Mackay, LK

DOI: https://hdl.handle.net/11343/359226

Thesis

Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response

van der Kooij, Monique K; Wetzels, Marjolein J A L; Aarts, Maureen J B et al. · 2020

DOI: https://dspace.library.uu.nl/handle/1874/440167

Thesis

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A et al. · 2022

Full title: The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

DOI: https://hdl.handle.net/1721.1/146821

Thesis

An Investigation into the Immunological Mechanisms of Immune Related Adverse Events Associated with Oncological Immune Checkpoint Inhibitors

Olsson-Brown, Anna · 2022

Full title: An Investigation into the Immunological Mechanisms of Immune Related Adverse Events Associated with Oncological Immune Checkpoint Inhibitors

Authors: Olsson-Brown, Anna

DOI: https://livrepository.liverpool.ac.uk/3154960/1/200131723_Jul2021.pdf

Thesis

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin et al. · 2018

Full title: Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

DOI: https://www.repository.cam.ac.uk/handle/1810/277642

Thesis

Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Zhang, J; Liang, W; Liang, H et al. · 2024

Full title: Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Authors: Zhang, J; Liang, W; Liang, H; Wang, X; He, J

DOI: https://hdl.handle.net/11343/350365

Thesis

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis

Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer

Li, C; Ferro, A; Mhatre, SK et al. · 2022

Full title: Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer

Authors: Li, C; Ferro, A; Mhatre, SK; Lu, D; Lawrance, M; Li, X; Li, S; Allen, S; Desai, J; Fakih, M; Cecchini, M; Pedersen, KS; Kim, TY; Reyes-Rivera, I; Segal, NH; Lenain, C

DOI: https://hdl.handle.net/11343/316894

Thesis

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

Portell, Andrew; Larios, Dalia; Piel, Brandon P. et al. · 2018

Full title: 3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

DOI: http://hdl.handle.net/1721.1/118112

Thesis

Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma

Wang, M; Qin, L; Thia, K et al. · 2025

Full title: Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma

Authors: Wang, M; Qin, L; Thia, K; Nguyen, T; MacDonald, S; Belobrov, S; Kranz, S; Goode, D; Trapani, JA; Wiesenfeld, D; Neeson, PJ

DOI: https://hdl.handle.net/11343/358856

Thesis

Priming systemic anti-tumor immunity via in situ immunomodulation of the tumor microenvironment

Milling, Lauren Elizabeth · 2022

Full title: Priming systemic anti-tumor immunity via in situ immunomodulation of the tumor microenvironment

Authors: Milling, Lauren Elizabeth

DOI: https://hdl.handle.net/1721.1/139220

Thesis

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma

Wolchok, JD; Chiarion-Sileni, V; Gonzalez, R et al. · 2022

Full title: Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma

DOI: https://hdl.handle.net/11343/301620

Thesis

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in advanced non-small cell lung cancer: a subanalysis of Asian patients in CheckMate 9LA

John, T; Sakai, H; Ikeda, S et al. · 2022

Full title: First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in advanced non-small cell lung cancer: a subanalysis of Asian patients in CheckMate 9LA

DOI: https://hdl.handle.net/11343/308143

Thesis

Efficacy of immune checkpoint inhibitors for in-transit melanoma

Tie, EN; Lai-Kwon, J; Rtshiladze, MA et al. · 2020

Full title: Efficacy of immune checkpoint inhibitors for in-transit melanoma

Authors: Tie, EN; Lai-Kwon, J; Rtshiladze, MA; Na, L; Bozzi, J; Read, T; Atkinson, V; Au-Yeung, G; Long, GV; McArthur, GA; Sandhu, S; Saw, R; Walpole, E; Menzies, A; Smithers, M; Gyorki, DE

DOI: https://hdl.handle.net/11343/246341

Thesis

Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Lammers, Marshall · 2025

Authors: Lammers, Marshall

DOI: https://escholarship.org/uc/item/62w1z16d

Thesis

A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Arnaud-Coffin, P; Maillet, D; Gan, HK et al. · 2021

Full title: A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Authors: Arnaud-Coffin, P; Maillet, D; Gan, HK; Stelmes, J-J; You, B; Dalle, S; Peron, J

DOI: https://hdl.handle.net/11343/285412

Thesis

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

Figueiredo, Carlos R; Kalirai, Helen; Sacco, Joseph J et al. · 2020

Full title: Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

Authors: Figueiredo, Carlos R; Kalirai, Helen; Sacco, Joseph J; Azevedo, Ricardo A; Duckworth, Andrew; Slupsky, Joseph R; Coulson, Judy M; Coupland, Sarah E

DOI: https://livrepository.liverpool.ac.uk/3074857/1/Journal%20of%20Pathology_Figueiredo_et_al-2020.pdf

Thesis

Longitudinale Veränderung der Immunzellzusammensetzung von Patient*innen mit kolorektalem Karzinom unter kombinatorischer Immuntherapie mit Avelumab

Martin, Markus Paul · 2025

Full title: Longitudinale Veränderung der Immunzellzusammensetzung von Patient*innen mit kolorektalem Karzinom unter kombinatorischer Immuntherapie mit Avelumab

Authors: Martin, Markus Paul

DOI: https://refubium.fu-berlin.de/handle/fub188/45863

Thesis

Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S. et al. · 2024

Full title: Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

DOI: https://dspace.library.uu.nl/handle/1874/454114

Thesis

Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Hilbers, ML; Dimitriou, F; Lau, P et al. · 2021

Full title: Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Authors: Hilbers, ML; Dimitriou, F; Lau, P; Bhave, P; McArthur, GA; Zimmer, L; Kudura, K; Gérard, CL; Levesque, MP; Michielin, O; Dummer, R; Cheng, PF; Mangana, J

DOI: https://hdl.handle.net/11343/289654

Thesis

Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Meehan, K; Leslie, C; Lucas, M et al. · 2020

Full title: Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Authors: Meehan, K; Leslie, C; Lucas, M; Jacques, A; Mirzai, B; Lim, J; Bulsara, M; Khan, Y; Wong, NC; Solomon, B; Sader, C; Friedland, P; Mir Arnau, G; Semple, T; Lim, AM

DOI: https://hdl.handle.net/11343/246366

Thesis

VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study

Smyth, Elizabeth; Knödler, Maren; Giraut, Anne et al. · 2020

Authors: Smyth, Elizabeth; Knödler, Maren; Giraut, Anne; Mauer, Murielle; Nilsson, Magnus; Van Grieken, Nicole; Wagner, Anna Dorothea; Moehler, Markus; Lordick, Florian

DOI: https://www.repository.cam.ac.uk/handle/1810/303757

Thesis

Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2020

Full title: Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

DOI: https://hdl.handle.net/11343/258389

Thesis

Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study

Koks, Marije S; Ocak, Gurbey; Suelmann, Britt B M et al. · 2021

Full title: Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study

Authors: Koks, Marije S; Ocak, Gurbey; Suelmann, Britt B M; Hulsbergen-Veelken, Cornelia A R; Haitjema, Saskia; Vianen, Marieke E; Verhaar, Marianne C; Kaasjager, Karin A H; Khairoun, Meriem

DOI: https://dspace.library.uu.nl/handle/1874/442933

Thesis

Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta · 2019

Full title: Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

Authors: van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta

DOI: https://dspace.library.uu.nl/handle/1874/390030

Thesis

High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

Wang, M; Huang, YK; Kong, JCH et al. · 2020

Full title: High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

DOI: https://hdl.handle.net/11343/246308

Thesis

Clinical trial data science to advance precision oncology

Plana, Deborah · 2022

Full title: Clinical trial data science to advance precision oncology

Authors: Plana, Deborah

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371907

Thesis

Therapeutic strategies to remodel immunologically cold tumors

Wang, M; Wang, S; Desai, J et al. · 2021

Full title: Therapeutic strategies to remodel immunologically cold tumors

Authors: Wang, M; Wang, S; Desai, J; Trapani, JA; Neeson, PJ

DOI: https://hdl.handle.net/11343/274073

Thesis

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

Liu, David V.; Liu, Derek; Jerby-Arnon, Livnat et al. · 2020

Full title: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

DOI: https://hdl.handle.net/1721.1/125847

Thesis

Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Taggart, David John · 2016

Full title: Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Authors: Taggart, David John

DOI: https://etheses.whiterose.ac.uk/id/eprint/16116/1/Thesis%20.pdf

Thesis

Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A et al. · 2022

Full title: Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

DOI: https://hdl.handle.net/1721.1/132258.2

Thesis

Immunosurveillance in clinical cancer management

Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M. et al. · 2024

Full title: Immunosurveillance in clinical cancer management

Authors: Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M.; Galluzzi, Lorenzo

DOI: https://dspace.library.uu.nl/handle/1874/454448

Thesis

Clinical pharmacology of anticancer agents with focus on neuro-oncology and biomarker assessment

van Bussel, Mark Theodorus Johannes · 2019

Full title: Clinical pharmacology of anticancer agents with focus on neuro-oncology and biomarker assessment

Authors: van Bussel, Mark Theodorus Johannes

DOI: https://dspace.library.uu.nl/handle/1874/383740

Thesis

Induction therapy with ipilimumab and nivolumab followed by consolidative chemoradiation as organ-sparing treatment in urothelial bladder cancer: study protocol of the INDIBLADE trial

Stockem, C. F.; Mellema, J. J.J.; van Rhijn, B. W.G. et al. · 2023

Full title: Induction therapy with ipilimumab and nivolumab followed by consolidative chemoradiation as organ-sparing treatment in urothelial bladder cancer: study protocol of the INDIBLADE trial

DOI: https://dspace.library.uu.nl/handle/1874/450053

Thesis

Activated osteoarthritis following immune checkpoint inhibitor treatment: An observational study

Reid, P; Liew, DFL; Akruwala, R et al. · 2021

Full title: Activated osteoarthritis following immune checkpoint inhibitor treatment: An observational study

Authors: Reid, P; Liew, DFL; Akruwala, R; Bass, AR; Chan, KK

DOI: https://hdl.handle.net/11343/289729

Thesis

Hematologic malignancies following immune checkpoint inhibition for solid tumors

van Eijs, Mick J.M.; van der Wagen, Lotte E.; Mous, Rogier et al. · 2023

Full title: Hematologic malignancies following immune checkpoint inhibition for solid tumors

DOI: https://dspace.library.uu.nl/handle/1874/446549

Thesis

The Biological and Immunological Effects of Irreversible Electroporation and Combination Therapy Options for the Improving the Treatment of Pancreatic Cancer

Brock, Rebecca Michaela · 2020

Full title: The Biological and Immunological Effects of Irreversible Electroporation and Combination Therapy Options for the Improving the Treatment of Pancreatic Cancer

Authors: Brock, Rebecca Michaela

DOI: http://hdl.handle.net/10919/98775

Thesis

A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Heinhuis, Kimberley Marga · 2020

Full title: A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Authors: Heinhuis, Kimberley Marga

DOI: https://dspace.library.uu.nl/handle/1874/400086

Thesis

Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report

Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak et al. · 2025

Full title: Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report

DOI: https://www.repository.cam.ac.uk/handle/1810/378106

Thesis

Association of good oncological response to therapy with the development of rheumatic immune-related adverse events following PD-1 inhibitor therapy

Liew, DFL; Leung, JLY; Liu, B et al. · 2021

Full title: Association of good oncological response to therapy with the development of rheumatic immune-related adverse events following PD-1 inhibitor therapy

Authors: Liew, DFL; Leung, JLY; Liu, B; Cebon, J; Frauman, AG; Buchanan, RRC

DOI: https://hdl.handle.net/11343/284891

Thesis

Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Saleh, R; Toor, SM; Al-Ali, D et al. · 2021

Full title: Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Authors: Saleh, R; Toor, SM; Al-Ali, D; Sasidharan Nair, V; Elkord, E

DOI: https://hdl.handle.net/11343/277709

Thesis

Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Mangsbo, Sara · 2009

Full title: Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Authors: Mangsbo, Sara

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110147

Thesis

Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander et al. · 2020

Full title: Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Authors: Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander; Morrison, Ryan D; O’Neill Reising, Leslie; Ackermann, Bradley L; Fill, Jeff A; Schade, Andrew E; Gruver, Aaron M

DOI: https://livrepository.liverpool.ac.uk/3091687/1/Analysis.pdf

Thesis

The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study

Holmberg, CJ; Ny, L; Hieken, TJ et al. · 2022

Full title: The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study

DOI: https://hdl.handle.net/11343/322130

Thesis

GPCRs as Next-Gen Targets for Immune Oncology

Wu, Victoria Huannyun · 2021

Full title: GPCRs as Next-Gen Targets for Immune Oncology

Authors: Wu, Victoria Huannyun

DOI: https://escholarship.org/uc/item/75p699pz

Thesis

Genomics-guided Oncology: Advancing Efficacy and Access

Zeverijn, Laurien J · 2024

Full title: Genomics-guided Oncology: Advancing Efficacy and Access

Authors: Zeverijn, Laurien J

DOI: https://dspace.library.uu.nl/handle/1874/457064

Thesis

New biomarkers for checkpoint inhibitor therapy

Burdett, N; Desai, J · 2021

Full title: New biomarkers for checkpoint inhibitor therapy

Authors: Burdett, N; Desai, J

DOI: https://hdl.handle.net/11343/277746

Thesis

Identifying Blood-Based Biomarkers of Efficacy, Toxicity and Outcome in Early-Stage Breast Cancer

Alkhafaji, Silver · 2025

Full title: Identifying Blood-Based Biomarkers of Efficacy, Toxicity and Outcome in Early-Stage Breast Cancer

Authors: Alkhafaji, Silver

DOI: https://escholarship.org/uc/item/2bx649ss

Thesis

The role of immune checkpoints in cardiovascular disease

Yousif, Laura I; Tanja, Anniek A; de Boer, Rudolf A et al. · 2022

Full title: The role of immune checkpoints in cardiovascular disease

Authors: Yousif, Laura I; Tanja, Anniek A; de Boer, Rudolf A; Teske, Arco J; Meijers, Wouter C

DOI: https://dspace.library.uu.nl/handle/1874/450612

Thesis

Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Regev, Aviv · 2020

Full title: Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Authors: Regev, Aviv

DOI: https://hdl.handle.net/1721.1/125032

Thesis

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C et al. · 2022

Full title: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

DOI: https://hdl.handle.net/1721.1/141282

Thesis

Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Ascierto, PA; McArthur, GA · 2020

Full title: Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Authors: Ascierto, PA; McArthur, GA

DOI: https://hdl.handle.net/11343/256879

Thesis

Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William et al. · 2025

Full title: Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

DOI: https://dspace.library.uu.nl/handle/1874/460578

Thesis

Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2021

Full title: Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

DOI: https://hdl.handle.net/11343/259450

Thesis

Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025

Full title: Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

DOI: https://hdl.handle.net/11343/360026

Thesis

Assessing the Effect of Combining BRAF, MEK, and Immune Checkpoint Inhibitors on the Immune Response to Cutaneous Melanoma

Patel, Riyaben Pankajkumar · 2024

Full title: Assessing the Effect of Combining BRAF, MEK, and Immune Checkpoint Inhibitors on the Immune Response to Cutaneous Melanoma

Authors: Patel, Riyaben Pankajkumar

DOI: https://hdl.handle.net/11343/354845

Thesis

Five latent factors underlie response to immunotherapy

Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A. et al. · 2024

Full title: Five latent factors underlie response to immunotherapy

DOI: https://dspace.library.uu.nl/handle/1874/458268

Thesis

Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events-A Comprehensive Review

Hommes, Josefien W; Verheijden, Rik J; Suijkerbuijk, Karijn P M et al. · 2021

Full title: Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events-A Comprehensive Review

Authors: Hommes, Josefien W; Verheijden, Rik J; Suijkerbuijk, Karijn P M; Hamann, Dörte

DOI: https://dspace.library.uu.nl/handle/1874/442368

Thesis

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Spranger-Zimmermann, Stefani · 2020

Full title: Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Authors: Spranger-Zimmermann, Stefani

DOI: https://hdl.handle.net/1721.1/126367

Thesis

Immune landscape of breast tumors with low and intermediate estrogen receptor expression

Voorwerk, Leonie; Sanders, Joyce; Keusters, Milou S. et al. · 2023

Full title: Immune landscape of breast tumors with low and intermediate estrogen receptor expression

Authors: Voorwerk, Leonie; Sanders, Joyce; Keusters, Milou S.; Balduzzi, Sara; Cornelissen, Sten; Duijst, Maxime; Lips, Esther H.; Sonke, Gabe S.; Linn, Sabine C.; Horlings, Hugo M.; Kok, Marleen

DOI: https://dspace.library.uu.nl/handle/1874/459152

Thesis

Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Lau, PKH; Feran, B; Smith, L et al. · 2022

Full title: Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

DOI: https://hdl.handle.net/11343/296832

Thesis

Neutrophils in the era of immune checkpoint blockade

Faget, Julien; Peters, Solange; Quantin, Xavier et al. · 2021

Full title: Neutrophils in the era of immune checkpoint blockade

Authors: Faget, Julien; Peters, Solange; Quantin, Xavier; Meylan, Etienne; Bonnefoy, Nathalie

DOI: https://infoscience.epfl.ch/handle/20.500.14299/181353

Thesis

Activity of Immunotherapy Regimens on Primary Renal Tumours: A Systematic Review

Jones, JO; Ince, WHJ; Welsh, SJ et al. · 2023

Full title: Activity of Immunotherapy Regimens on Primary Renal Tumours: A Systematic Review

Authors: Jones, JO; Ince, WHJ; Welsh, SJ; Stewart, GD

DOI: https://www.repository.cam.ac.uk/handle/1810/345156

Thesis

Immune profiling of pediatric solid tumors

Terry, RL; https://orcid.org/0000-0002-6260-7372; Meyran, D et al. · 2020

Full title: Immune profiling of pediatric solid tumors

DOI: http://hdl.handle.net/1959.4/unsworks_80081

Thesis

Adjuvant therapy for stage II melanoma: the need for further studies

Lee, Rebecca; Mandala, Mario; Long, Georgina V. et al. · 2023

Full title: Adjuvant therapy for stage II melanoma: the need for further studies

Authors: Lee, Rebecca; Mandala, Mario; Long, Georgina V.; Eggermont, Alexander M.M.; van Akkooi, Alexander C.J.; Sandhu, Shahneen; Garbe, Claus; Lorigan, Paul

DOI: https://dspace.library.uu.nl/handle/1874/459368

Thesis

Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis

van der Leij, Stephanie; Suijkerbuijk, Karijn P M; van den Broek, Medard F M et al. · 2024

Full title: Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis

Authors: van der Leij, Stephanie; Suijkerbuijk, Karijn P M; van den Broek, Medard F M; Valk, Gerlof D; Dankbaar, Jan Willem; van Santen, Hanneke M

DOI: https://dspace.library.uu.nl/handle/1874/455308

Thesis

CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Millen, R; Hendry, S; Narasimhan, V et al. · 2020

Full title: CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Authors: Millen, R; Hendry, S; Narasimhan, V; Abbott, R; Croxford, M; Gibbs, P; Tie, J; Wong, HL; Jones, I; Kosmider, S; Byrne, D; Zalcberg, J; Fox, S; Desai, J; Visvanathan, K; Ramsay, RG; Tran, B

DOI: https://hdl.handle.net/11343/247670

Thesis

An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape

Anton, A; Hutchinson, R; Hovens, CM et al. · 2025

Full title: An immune suppressive tumor microenvironment in primary prostate cancer promotes tumor immune escape

Authors: Anton, A; Hutchinson, R; Hovens, CM; Christie, M; Ryan, A; Gibbs, P; Costello, A; Peters, J; Neeson, PJ; Corcoran, NM; Tran, B

DOI: https://hdl.handle.net/11343/359317

Thesis

**Authors:** RAPUANO LEMBO, ROSA **Institution:** Università degli Studi di Milano (AIR) **Date:** 2025-12-19

RAPUANO LEMBO, ROSA · 2025

Full title: **Authors:** RAPUANO LEMBO, ROSA **Institution:** Università degli Studi di Milano (AIR) **Date:** 2025-12-19

Authors: RAPUANO LEMBO, ROSA

DOI: http://dx.doi.org/10.13130/rapuano-lembo-rosa_phd2025-12-19

Thesis

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Rashidian, Mohammad; Ingram, Jessica R.; Dougan, Michael et al. · 2018

Full title: Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

DOI: http://hdl.handle.net/1721.1/115202

Thesis

Immune checkpoint inhibitors in infectious disease

King, HAD; Lewin, SR · 2025

Full title: Immune checkpoint inhibitors in infectious disease

Authors: King, HAD; Lewin, SR

DOI: https://hdl.handle.net/11343/358581

Thesis

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

None · 2021

Full title: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Authors: None

DOI: https://hdl.handle.net/1721.1/136118

Thesis

Understanding the molecular basis of cancer immunotherapy for melanoma

Huang, Xinyao · 2025

Full title: Understanding the molecular basis of cancer immunotherapy for melanoma

Authors: Huang, Xinyao

DOI: https://dspace.library.uu.nl/handle/1874/457137

Thesis

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M. et al. · 2024

Full title: Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

DOI: https://dspace.library.uu.nl/handle/1874/455323

Thesis

Breast cancer cells and PD-1/PD-L1 blockade upregulate the expression of PD-1, CTLA-4, TIM-3 and LAG-3 immune checkpoints in CD4+ T cells

Saleh, R; Toor, SM; Khalaf, S et al. · 2021

Full title: Breast cancer cells and PD-1/PD-L1 blockade upregulate the expression of PD-1, CTLA-4, TIM-3 and LAG-3 immune checkpoints in CD4+ T cells

Authors: Saleh, R; Toor, SM; Khalaf, S; Elkord, E

DOI: https://hdl.handle.net/11343/277642

Thesis

Novel Role of PPAR-Gamma in GM-CSF Induced Anti-Tumor Immunity

Goyal, Girija · 2015

Full title: Novel Role of PPAR-Gamma in GM-CSF Induced Anti-Tumor Immunity

Authors: Goyal, Girija

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226102

Thesis

Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

Ye, Weiyu; Olsson-Brown, Anna; Watson, Robert A et al. · 2021

Full title: Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

Thesis

First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Hegewisch-Becker, S; Mendez, G; Chao, J et al. · 2025

Full title: First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

DOI: https://hdl.handle.net/11343/358332

Thesis

Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors

Nasca, Vincenzo; Zhao, Joseph; Ros, Javier et al. · 2025

Full title: Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors

DOI: https://dspace.library.uu.nl/handle/1874/460579

Thesis

Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Trujillo, Jonathan A; Luke, Jason J; Zha, Yuanyuan et al. · 2020

Full title: Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

Authors: Trujillo, Jonathan A; Luke, Jason J; Zha, Yuanyuan; Segal, Jeremy P; Ritterhouse, Lauren L; Spranger-Zimmermann, Stefani; Matijevich, Karen; Gajewski, Thomas F

DOI: https://hdl.handle.net/1721.1/126359

Thesis

Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

Aristin Revilla, Sonia; Kranenburg, Onno; Coffer, Paul J. · 2022

Full title: Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

Authors: Aristin Revilla, Sonia; Kranenburg, Onno; Coffer, Paul J.

DOI: https://dspace.library.uu.nl/handle/1874/453924

Thesis

The delicate balance of melanoma immunotherapy

Gyorki, DE; Callahan, M; Wolchok, JD et al. · 2022

Full title: The delicate balance of melanoma immunotherapy

Authors: Gyorki, DE; Callahan, M; Wolchok, JD; Ariyan, CE

DOI: https://hdl.handle.net/11343/304507

Thesis

Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2022

Full title: Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review

Authors: Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G; van Diest, Paul J; Pluim, Josien P W; Verhoeff, Joost J C; de Jong, Pim A; Leiner, Tim; Veta, Mitko; Suijkerbuijk, Karijn P M

DOI: https://dspace.library.uu.nl/handle/1874/447089

Thesis

Novel biomarkers for melanoma immunotherapy

Wong, Ngai Man Annie · 2020

Full title: Novel biomarkers for melanoma immunotherapy

Authors: Wong, Ngai Man Annie

DOI: http://hdl.handle.net/11343/252887

Thesis

**Authors:** Sidiropoulos, Dimitrios Nikolaos **Institution:** Johns Hopkins University **Date:** 2024-01-03T16:16:50Z

Sidiropoulos, Dimitrios Nikolaos · 2024

Full title: **Authors:** Sidiropoulos, Dimitrios Nikolaos **Institution:** Johns Hopkins University **Date:** 2024-01-03T16:16:50Z

Authors: Sidiropoulos, Dimitrios Nikolaos

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/69091

Thesis

Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

van Eijs, Mick J.M.; ter Linde, José J.M.; Baars, Matthijs J.D. et al. · 2023

Full title: Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

DOI: https://dspace.library.uu.nl/handle/1874/450094

Thesis

Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma

Fröhlich, A; Loick, S; Bawden, EG et al. · 2021

DOI: https://hdl.handle.net/11343/277648

Thesis

Tarloxotinib amplifies the anti-tumour efficacy of immune checkpoint inhibitors through multiple mechanisms

Fu, Zhe · 2020

Full title: Tarloxotinib amplifies the anti-tumour efficacy of immune checkpoint inhibitors through multiple mechanisms

Authors: Fu, Zhe

DOI: https://hdl.handle.net/2292/52722

Thesis

The Gut Microbiome Shapes the Tumor Microenvironment by Tuning Innate Immunity

Fessler, Jessica Lynn · 2021

Full title: The Gut Microbiome Shapes the Tumor Microenvironment by Tuning Innate Immunity

Authors: Fessler, Jessica Lynn

DOI: https://knowledge.uchicago.edu/record/2823/files/Fessler_uchicago_0330D_15632.pdf

Thesis

Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

Roberts, A; Bentley, L; Tang, T et al. · 2021

Full title: Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

DOI: https://hdl.handle.net/11343/273022

Thesis

Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and dependent on IL23 and IFNg

Lo, Jonathan; Cozzetto, Domenico; Alexander, James et al. · 2023

Full title: Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and dependent on IL23 and IFNg

DOI: https://www.nature.com/articles/s41467-023-41798-2

Thesis

CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Wang, J; Li, X; Xiao, G et al. · 2024

Full title: CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Authors: Wang, J; Li, X; Xiao, G; Desai, J; Frentzas, S; Wang, ZM; Xia, Y; Li, B

DOI: https://hdl.handle.net/11343/350752

Thesis

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Saleh, R; Taha, RZ; Toor, SM et al. · 2021

Full title: Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Authors: Saleh, R; Taha, RZ; Toor, SM; Sasidharan Nair, V; Murshed, K; Khawar, M; Al-Dhaheri, M; Petkar, MA; Abu Nada, M; Elkord, E

DOI: https://hdl.handle.net/11343/277749

Thesis

The Role of TIM-3 in Glioblastoma Progression

Ahmady, F; Sharma, A; Achuthan, AA et al. · 2025

Full title: The Role of TIM-3 in Glioblastoma Progression

Authors: Ahmady, F; Sharma, A; Achuthan, AA; Kannourakis, G; Luwor, RB

DOI: https://hdl.handle.net/11343/360090

Thesis

Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP] et al. · 2025

Full title: Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Authors: Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP]; Dias, Queila Cristina; Pinheiro Fantinatti, Alexandra; Fávaro, Wagner José

DOI: http://dx.doi.org/10.3390/ani13121888

Thesis

Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Carbone, DP; Ciuleanu, TE; Schenker, M et al. · 2024

DOI: https://hdl.handle.net/11343/352762

Thesis

Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

Naik, Girish; Waikar, Sushrut S.; Johnson, Alistair Edward William et al. · 2020

Full title: Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

Authors: Naik, Girish; Waikar, Sushrut S.; Johnson, Alistair Edward William; Buchbinder, Elizabeth I.; Haq, Rizwan; Hodi, F. Stephen; Schoenfeld, Jonathan D.; Ott, Patrick A.

DOI: https://hdl.handle.net/1721.1/124317

Thesis

Active immunization with a Her-2/neu-targeting Multi-peptide B cell vaccine prevents lung metastases formation from Her-2/neu breast cancer in a mouse model

Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Drinić, Mirjana (Medical University of Vienna) et al. · 2022

Full title: Active immunization with a Her-2/neu-targeting Multi-peptide B cell vaccine prevents lung metastases formation from Her-2/neu breast cancer in a mouse model

DOI: https://phaidra.vetmeduni.ac.at/o:1804

Thesis

The study on myeloid-derived suppressor cells (MDSCs) and T cells in melanoma patients with adverse events after immunotherapy immune checkpoint inhibitors

Lepper, Alisa Helen · 2025

Full title: The study on myeloid-derived suppressor cells (MDSCs) and T cells in melanoma patients with adverse events after immunotherapy immune checkpoint inhibitors

Authors: Lepper, Alisa Helen

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/36613/1/Doktorarbeit_Alisa_Lepper_Version_zur_Abgabe.pdf

Thesis

Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Veinalde, Rūta · 2017

Full title: Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Authors: Veinalde, Rūta

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/23094/1/R.Veinalde_Thesis_print.pdf

Thesis

Tumor immunosurveiliance: Innate immune activation as a mechanistic prerequisite for efficient immune checkpoint blockade in cancer immunotherapy

Wintges, Alexander F. G. · 2018

Full title: Tumor immunosurveiliance: Innate immune activation as a mechanistic prerequisite for efficient immune checkpoint blockade in cancer immunotherapy

Authors: Wintges, Alexander F. G.

DOI: https://mediatum.ub.tum.de/1436586

Thesis

Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Ahern, E; Solomon, BJ; Hui, R et al. · 2021

Full title: Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Authors: Ahern, E; Solomon, BJ; Hui, R; Pavlakis, N; O'Byrne, K; Hughes, BGM

DOI: https://hdl.handle.net/11343/287197

Thesis

Case of nivolumab-induced sclerosing cholangitis: Lessons from long-term follow-up

McClure, T; Cui, W; Asadi, K et al. · 2020

Full title: Case of nivolumab-induced sclerosing cholangitis: Lessons from long-term follow-up

Authors: McClure, T; Cui, W; Asadi, K; John, T; Testro, A

DOI: https://hdl.handle.net/11343/252197

Thesis

Long-Term Survival in Patients With Advanced Melanoma

van Not, Olivier J; van den Eertwegh, Alfons J M; Groningen, University et al. · 2024

Full title: Long-Term Survival in Patients With Advanced Melanoma

DOI: https://dspace.library.uu.nl/handle/1874/455362

Thesis

Immune checkpoint blockade in renal cell carcinoma

Rappold, PM; Silagy, AW; Kotecha, RR et al. · 2022

Full title: Immune checkpoint blockade in renal cell carcinoma

Authors: Rappold, PM; Silagy, AW; Kotecha, RR; Hakimi, AA

DOI: https://hdl.handle.net/11343/298242

Thesis

PD-L1 expression and prediction of response to immune modulators in non-small cell lung cancer : reasons for its fragility and strategies to reduce it

Haragan, Alexander · 2021

Full title: PD-L1 expression and prediction of response to immune modulators in non-small cell lung cancer : reasons for its fragility and strategies to reduce it

Authors: Haragan, Alexander

DOI: https://livrepository.liverpool.ac.uk/3125235/1/201313407_May2021.pdf

Thesis

Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance

Verheijden, Rik J; van Eijs, Mick J M; May, Anne M et al. · 2023

Full title: Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance

Authors: Verheijden, Rik J; van Eijs, Mick J M; May, Anne M; van Wijk, Femke; Suijkerbuijk, Karijn P M

DOI: https://dspace.library.uu.nl/handle/1874/449140

Thesis

Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Bhave, P; Pallan, L; Long, GV et al. · 2022

Full title: Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

DOI: https://hdl.handle.net/11343/304521

Thesis

Early phase clinical studies of novel immunotherapeutics in oncology

Ros, Wilhelmina · 2019

Full title: Early phase clinical studies of novel immunotherapeutics in oncology

Authors: Ros, Wilhelmina

DOI: https://dspace.library.uu.nl/handle/1874/384382

Thesis

Uso do ipilimumabe em pacientes com melanoma metastático

Henriques, Vivian Saccomano [UNESP] · 2018

Full title: Uso do ipilimumabe em pacientes com melanoma metastático

Authors: Henriques, Vivian Saccomano [UNESP]

DOI: http://hdl.handle.net/11449/154827

Thesis

Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis

Mulder, F. J.; de Ruiter, E. J.; Gielgens, T. F.B. et al. · 2025

Full title: Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis

Authors: Mulder, F. J.; de Ruiter, E. J.; Gielgens, T. F.B.; Farshadpour, F.; de Bree, R.; van den Hout, M. F.C.M.; Kremer, B.; Willems, S. M.; Speel, E. J.M.

DOI: https://dspace.library.uu.nl/handle/1874/460913

Thesis

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Bhave, P; Ahmed, T; Lo, SN et al. · 2022

Full title: Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

DOI: https://hdl.handle.net/11343/316921

Thesis

Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

Devaud, C; John, LB; Westwood, JA et al. · 2021

Full title: Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

Authors: Devaud, C; John, LB; Westwood, JA; Darcy, PK; Kershaw, MH

DOI: https://hdl.handle.net/11343/265570

Thesis

PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Melaiu, O; Mina, M; Chierici, M et al. · 2017

Full title: PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

DOI: http://hdl.handle.net/1959.4/unsworks_44362

Thesis

Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Liu, David; Regev, Aviv · 2020

Full title: Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Authors: Liu, David; Regev, Aviv

DOI: https://hdl.handle.net/1721.1/124400

Thesis

Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?

Cheung, VTF; Gupta, T; Olsson-Brown, A et al. · 2020

Full title: Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?

DOI: http://hdl.handle.net/1959.4/unsworks_76597

Thesis

Pre-operative ablative radiotherapy in combination with immunotherapy and novel agents in pancreatic cancer

Buckley, Hannah · 2024

Full title: Pre-operative ablative radiotherapy in combination with immunotherapy and novel agents in pancreatic cancer

Authors: Buckley, Hannah

DOI: https://www.repository.cam.ac.uk/handle/1810/363822

Thesis

Tumour-draining lymph nodes in head and neck cancer : immunological signatures and clinical implications

Krzysztof Piersiala (18659740) · 2024

Full title: Tumour-draining lymph nodes in head and neck cancer : immunological signatures and clinical implications

Authors: Krzysztof Piersiala (18659740)

DOI: oai:figshare.com:article/26909803

Thesis

Physical activity and checkpoint inhibition: association with toxicity and survival

Verheijden, Rik J; Cabané Ballester, Anna; Smit, Karel C et al. · 2024

Full title: Physical activity and checkpoint inhibition: association with toxicity and survival

Authors: Verheijden, Rik J; Cabané Ballester, Anna; Smit, Karel C; van Eijs, Mick J M; Bruijnen, Cheryl P; van Lindert, Anne S R; Suijkerbuijk, Karijn P M; May, Anne M

DOI: https://dspace.library.uu.nl/handle/1874/450548

Thesis

F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Wong, A; Callahan, J; Keyaerts, M et al. · 2020

Full title: F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Authors: Wong, A; Callahan, J; Keyaerts, M; Neyns, B; Mangana, J; Aberle, S; Herschtal, A; Fullerton, S; Milne, D; Iravani, A; McArthur, GA; Hicks, RJ

DOI: https://hdl.handle.net/11343/246372

Thesis

DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

Jacobs, Marleen; Pouw, Juliëtte; Olde Nordkamp, Michel et al. · 2020

Full title: DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

Authors: Jacobs, Marleen; Pouw, Juliëtte; Olde Nordkamp, Michel; Radstake, Timothy; Leijten, Emmerik; Boes, Marianne

DOI: https://dspace.library.uu.nl/handle/1874/457405

Thesis

A Retrospective Review and Comprehensive Tumour Profiling of Advanced Non-Melanomatous Cutaneous Spindle Cell Neoplasms Treated with Immune-Checkpoint Inhibitors

McLean, LS; Lim, AM; Angel, C et al. · 2024

Full title: A Retrospective Review and Comprehensive Tumour Profiling of Advanced Non-Melanomatous Cutaneous Spindle Cell Neoplasms Treated with Immune-Checkpoint Inhibitors

Authors: McLean, LS; Lim, AM; Angel, C; Young, RJ; Pizzolla, A; Archer, S; Solomon, BJ; Thai, AA; Lewin, J; Rischin, D

DOI: https://hdl.handle.net/11343/345505

Thesis

Mechanistic Elucidation and Therapeutic Improvement of Anti-CTLA-4 Therapies

Lax, Brianna Marie · 2023

Full title: Mechanistic Elucidation and Therapeutic Improvement of Anti-CTLA-4 Therapies

Authors: Lax, Brianna Marie

DOI: https://hdl.handle.net/1721.1/151592

Thesis

Programmed Death-Ligand 1 Copy Number Loss in NSCLC Associates With Reduced Programmed Death-Ligand 1 Tumor Staining and a Cold Immunophenotype

Aujla, S; Aloe, C; Vannitamby, A et al. · 2022

Full title: Programmed Death-Ligand 1 Copy Number Loss in NSCLC Associates With Reduced Programmed Death-Ligand 1 Tumor Staining and a Cold Immunophenotype

Authors: Aujla, S; Aloe, C; Vannitamby, A; Hendry, S; Rangamuwa, K; Wang, H; Vlahos, R; Selemidis, S; Leong, T; Steinfort, D; Bozinovski, S

DOI: https://hdl.handle.net/11343/308995

Thesis

T-cell surveillance of therapy-induced senescent lymphoma cells in the presence of anti-CD19/CD20 × CD3 bispecific antibodies

Cai, Xiurong · 2023

Full title: T-cell surveillance of therapy-induced senescent lymphoma cells in the presence of anti-CD19/CD20 × CD3 bispecific antibodies

Authors: Cai, Xiurong

DOI: https://refubium.fu-berlin.de/handle/fub188/40608

Thesis

75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr. et al. · 2024

Full title: 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

DOI: https://www.repository.cam.ac.uk/handle/1810/372324

Thesis

Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

Fleury, Michelle; Belkina, Anna C; Proctor, Elizabeth A et al. · 2022

Full title: Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

Authors: Fleury, Michelle; Belkina, Anna C; Proctor, Elizabeth A; Zammitti, Christopher; Simms, Robert W; Lauffenburger, Douglas A; Snyder-Cappione, Jennifer E; Lafyatis, Robert; Dooms, Hans

DOI: https://hdl.handle.net/1721.1/134856.2

Thesis

Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Arriola, Edurne; Wheater, Matthew; Galea, Ian et al. · 2016

Full title: Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Thesis

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A; Villaudy, Julien et al. · 2022

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

DOI: https://dspace.library.uu.nl/handle/1874/448076

Thesis

Perspectives on the role of "-Omics" in predicting response to immunotherapy

Di Giacomo, Anna Maria; Subudhi, Sumit; Vos, Wim et al. · 2025

Full title: Perspectives on the role of "-Omics" in predicting response to immunotherapy

DOI: https://dspace.library.uu.nl/handle/1874/460980

Thesis

**Authors:** Jallad, Mary-Ann **Institution:** American University of Beirut **Date:** 2020-12-29T07:39:17Z

Jallad, Mary-Ann · 2020

Full title: **Authors:** Jallad, Mary-Ann **Institution:** American University of Beirut **Date:** 2020-12-29T07:39:17Z

Authors: Jallad, Mary-Ann

DOI: http://hdl.handle.net/10938/22166

Thesis

Cost-effectiveness and financial risks associated with immune checkpoint inhibitor therapy

Kim, H; Liew, D; Goodall, S · 2021

Full title: Cost-effectiveness and financial risks associated with immune checkpoint inhibitor therapy

Authors: Kim, H; Liew, D; Goodall, S

DOI: https://hdl.handle.net/11343/275928

Thesis

Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

DOI: https://hdl.handle.net/11343/359086

Thesis

Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

Colombo, AR; Hav, M; Singh, M et al. · 2022

Full title: Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

DOI: https://hdl.handle.net/11343/318236

Thesis

Defining the tumour microenvironment landscape of melanoma immunotherapy

Bai, Xinyu · 2025

Full title: Defining the tumour microenvironment landscape of melanoma immunotherapy

Authors: Bai, Xinyu

DOI: https://hdl.handle.net/2123/33848

Thesis

Tumor-infiltrating lymphocytes and immune-related adverse events in advanced melanoma

van Duin, I. A.J.; Schuiveling, M.; ter Maat, L. S. et al. · 2024

Full title: Tumor-infiltrating lymphocytes and immune-related adverse events in advanced melanoma

DOI: https://dspace.library.uu.nl/handle/1874/454112

Thesis

Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

Long, GV; Shklovskaya, E; Satgunaseelan, L et al. · 2025

Full title: Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma

DOI: https://hdl.handle.net/11343/360002

Thesis

Checkpoint Genes at the Cancer Side of the Immunological Synapse in Bladder Cancer

Dobosz, Paula; Stempor, Przemysław A; Roszik, Jason et al. · 2020

Full title: Checkpoint Genes at the Cancer Side of the Immunological Synapse in Bladder Cancer

Authors: Dobosz, Paula; Stempor, Przemysław A; Roszik, Jason; Herman, Amir; Layani, Adi; Berger, Raanan; Avni, Dror; Sidi, Yechezkel; Leibowitz-Amit, Raya

DOI: https://www.repository.cam.ac.uk/handle/1810/301473

Thesis

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

Halse, H; Colebatch, AJ; Petrone, P et al. · 2020

Full title: Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

DOI: https://hdl.handle.net/11343/251140

Thesis

Understanding and Overcoming the Non-T cell-inflamed Tumor Microenvironment

Higgs, Emily Faye · 2022

Full title: Understanding and Overcoming the Non-T cell-inflamed Tumor Microenvironment

Authors: Higgs, Emily Faye

DOI: https://knowledge.uchicago.edu/record/3592/files/Higgs_uchicago_0330D_16081.pdf

Thesis

Further Knowledge and Developments in Resistance Mechanisms to Immune Checkpoint Inhibitors

Berland, Lea; Gabr, Zeina; Chang, Michelle et al. · 2025

Full title: Further Knowledge and Developments in Resistance Mechanisms to Immune Checkpoint Inhibitors

Authors: Berland, Lea; Gabr, Zeina; Chang, Michelle; Ilie, Marius I; Hofman, Veronique; Rignol, Guylene; GHIRINGHELLI, Francois; Mograbi, Baharia; Rashidian, M.; Hofman, Paul

DOI: https://infoscience.epfl.ch/handle/20.500.14299/252010

Thesis

Mechanisms of immune checkpoint inhibitor-induced gastrointestinal toxicities

Nahar, Kazi Jannatun · 2022

Full title: Mechanisms of immune checkpoint inhibitor-induced gastrointestinal toxicities

Authors: Nahar, Kazi Jannatun

DOI: https://hdl.handle.net/2123/29500

Thesis

Evaluation des Einflusses der PD-1-Inhibition auf die Effektivität der chimären Antigenrezeptor (CAR) T-Zelltherapie im Neuroblastom

Töws, Karin · 2022

Full title: Evaluation des Einflusses der PD-1-Inhibition auf die Effektivität der chimären Antigenrezeptor (CAR) T-Zelltherapie im Neuroblastom

Authors: Töws, Karin

DOI: https://refubium.fu-berlin.de/handle/fub188/34526

Thesis

Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Duarte, JDG; Parakh, S; Andrews, MC et al. · 2020

Authors: Duarte, JDG; Parakh, S; Andrews, MC; Woods, K; Pasam, A; Tutuka, C; Ostrouska, S; Blackburn, JM; Behren, A; Cebon, J

DOI: https://hdl.handle.net/11343/256187

Thesis

Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study

Wells, JC; Dudani, S; Gan, CL et al. · 2021

Full title: Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study

DOI: https://hdl.handle.net/11343/288773

Thesis

Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

Dranoff, Glenn; Kwan, Byron Hua; Zhu, Eric Franklin et al. · 2018

Full title: Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

DOI: http://hdl.handle.net/1721.1/114593

Thesis

Antibody-based immunotherapy of cancer : From optimization to novel approaches

van Hooren, Luuk · 2018

Full title: Antibody-based immunotherapy of cancer : From optimization to novel approaches

Authors: van Hooren, Luuk

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342799

Thesis

Exploring germline contribution to response and toxicity to treatment with anti-PD-1/PD-L1 for non-small cell lung cancer by whole genome sequencing

Barnet, Megan; https://orcid.org/0000-0003-3243-2716 · 2021

Full title: Exploring germline contribution to response and toxicity to treatment with anti-PD-1/PD-L1 for non-small cell lung cancer by whole genome sequencing

Authors: Barnet, Megan ; https://orcid.org/0000-0003-3243-2716

DOI: http://hdl.handle.net/1959.4/100563

Thesis

Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Pühl, Miriam · 2024

Full title: Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Authors: Pühl, Miriam

DOI: https://refubium.fu-berlin.de/handle/fub188/40924

Thesis

Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies, Mikhail; Roberts, Edward W.; Kersten, Kelly et al. · 2018

Full title: Understanding the tumor immune microenvironment (TIME) for effective therapy

DOI: http://hdl.handle.net/1721.1/119415

Thesis

NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy

Cazzetta, Valentina; Depierreux, Delphine; Colucci, Francesco et al. · 2023

Full title: NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy

Authors: Cazzetta, Valentina; Depierreux, Delphine; Colucci, Francesco; Mikulak, Joanna; Mavilio, Domenico

DOI: https://www.repository.cam.ac.uk/handle/1810/348052

Thesis

Triplet Therapy in Melanoma — Combined BRAF/MEK Inhibitors and Anti-PD-(L)1 Antibodies

Dixon-Douglas, JR; Patel, RP; Somasundram, PM et al. · 2022

Full title: Triplet Therapy in Melanoma — Combined BRAF/MEK Inhibitors and Anti-PD-(L)1 Antibodies

Authors: Dixon-Douglas, JR; Patel, RP; Somasundram, PM; McArthur, GA

DOI: https://hdl.handle.net/11343/308250

Thesis

CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2023

Full title: CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

DOI: https://dspace.library.uu.nl/handle/1874/448890

Thesis

Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme

Hernandez, Amanda L.; Lowther, Daniel E.; Lucca, Liliana E. et al. · 2017

Full title: Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme

Authors: Hernandez, Amanda L.; Lowther, Daniel E.; Lucca, Liliana E.; Lerner, Benjamin A.; Gunel, Murat; Raddassi, Khadir; Coric, Vlad; Hafler, David A.; Thomas, Brittany A.; Love, John C

DOI: http://hdl.handle.net/1721.1/111673

Thesis

Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review

Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth · 2022

Full title: Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review

Authors: Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth

DOI: https://www.repository.cam.ac.uk/handle/1810/343973

Thesis

A gut microbial signature for combination immune checkpoint blockade across cancer types

Gunjur, A; Shao, Y; Rozday, T et al. · 2024

Full title: A gut microbial signature for combination immune checkpoint blockade across cancer types

DOI: https://hdl.handle.net/11343/353256

Thesis

Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab – study protocol

Janssen, J. C.; van Dijk, B.; de Joode, K. et al. · 2024

DOI: https://dspace.library.uu.nl/handle/1874/453272

Thesis

The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M. et al. · 2023

Full title: The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

DOI: https://dspace.library.uu.nl/handle/1874/459059

Thesis

IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Dunkel, IJ; Cohen, K; Foreman, NK et al. · 2022

Full title: IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

DOI: https://hdl.handle.net/11343/318235

Thesis

Predicting immunotherapy outcomes in advanced melanoma: Clinical, radiological, and pathological approaches

van Duin, Belle · 2025

Full title: Predicting immunotherapy outcomes in advanced melanoma: Clinical, radiological, and pathological approaches

Authors: van Duin, Belle

DOI: https://dspace.library.uu.nl/handle/1874/457130

Thesis

Immunotherapy for gastric cancer: Time for a personalized approach?

Dolcetti, R; De Re, V; Canzonieri, V · 2021

Full title: Immunotherapy for gastric cancer: Time for a personalized approach?

Authors: Dolcetti, R; De Re, V; Canzonieri, V

DOI: https://hdl.handle.net/11343/272157

Thesis

The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

Thompson, Nicola A; Stewart, Grant D; Welsh, Sarah J et al. · 2022

Full title: The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

DOI: https://www.repository.cam.ac.uk/handle/1810/334470

Thesis

Photon versus carbon ion radiotherapy – combining radiotherapy with immune checkpoint blockade in the EO771 breast cancer model

Hartmann, Laura · 2022

Full title: Photon versus carbon ion radiotherapy – combining radiotherapy with immune checkpoint blockade in the EO771 breast cancer model

Authors: Hartmann, Laura

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/30065/7/Laura_Hartmann_PhD_Thesis.pdf

Thesis

Prognostická rola kontrolných bodov imunitných reakcií u pacientok s ovariálnym karcinómom

Raková, Jana · 2019

Full title: Prognostická rola kontrolných bodov imunitných reakcií u pacientok s ovariálnym karcinómom

Authors: Raková, Jana

DOI: http://hdl.handle.net/20.500.11956/98153

Thesis

A prediction model for response to immune checkpoint inhibition in advanced melanoma

van Duin, Isabella A J; Verheijden, Rik J; van Diest, Paul J et al. · 2024

Full title: A prediction model for response to immune checkpoint inhibition in advanced melanoma

DOI: https://dspace.library.uu.nl/handle/1874/451246

Thesis

A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens

Lee, YH; Huang, CY; Hsieh, YH et al. · 2024

Full title: A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens

Authors: Lee, YH; Huang, CY; Hsieh, YH; Yang, CH; Hung, YL; Chen, YA; Lin, YC; Lin, CH; Lee, JH; Wang, MY; Kuo, WH; Lin, YY; Lu, YS

DOI: https://hdl.handle.net/11343/351520

Thesis

Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells

Gerton, Thomas J.; Green, Allen; Campisi, Marco et al. · 2023

Full title: Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells

DOI: https://hdl.handle.net/1721.1/152071

Thesis

Production of Preclinical Grade Recombinant Newcastle disease viruses to Enhance Tumor Specific Immune Responses in Syngeneic Mouse Models of Cancer

Santry, Lisa · 2018

Full title: Production of Preclinical Grade Recombinant Newcastle disease viruses to Enhance Tumor Specific Immune Responses in Syngeneic Mouse Models of Cancer

Authors: Santry, Lisa

DOI: http://hdl.handle.net/10214/12313

Thesis

Faktory ovplyvňujúce účinnosť protinádorovej terapie blokujúcej signalizačnú dráhu PD-1/PD-L1 a prediktívne biomarkery tejto liečby

Majerová, Miriam · 2019

Full title: Faktory ovplyvňujúce účinnosť protinádorovej terapie blokujúcej signalizačnú dráhu PD-1/PD-L1 a prediktívne biomarkery tejto liečby

Authors: Majerová, Miriam

DOI: http://hdl.handle.net/20.500.11956/106652

Thesis

Upcoming immunotherapeutic combinations for B-cell lymphoma

Greve, Patrick; Meyer Wentrup, Friederike; Peperzak, Victor et al. · 2021

Full title: Upcoming immunotherapeutic combinations for B-cell lymphoma

Authors: Greve, Patrick; Meyer Wentrup, Friederike; Peperzak, Victor; Boes, Marianne

DOI: https://dspace.library.uu.nl/handle/1874/442691

Thesis

Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Klein, O; Senko, C; Carlino, MS et al. · 2022

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Authors: Klein, O; Senko, C; Carlino, MS; Markman, B; Jackett, L; Gao, B; Lum, C; Kee, D; Behren, A; Palmer, J; Cebon, J

DOI: https://hdl.handle.net/11343/304665

Thesis

SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, A; Iravani, A; Lasocki, A et al. · 2021

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, A; Iravani, A; Lasocki, A; Wallace, R; Weppler, A; Au-Yeung, G; Sachithanandan, N; Chiang, CY; Wentworth, J; Colman, PG; Kay, TW; Krishnamurthy, B; Sandhu, S

DOI: https://hdl.handle.net/11343/273859

Thesis

Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E. et al. · 2020

Full title: Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Authors: Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E.; Umeton, Renato; Albayrak, Adem; Subegdjo, Safiya J.; Johnson, Bruce E.; Nishino, Mizuki; Sholl, Lynette M.; Awad, Mark M.

DOI: https://hdl.handle.net/1721.1/128646

Thesis

Biomarker-driven Immunotherapy in Patients with Advanced Solid Tumors: Providing Access and Refining Patient Selection

Geurts, Birgit · 2024

Full title: Biomarker-driven Immunotherapy in Patients with Advanced Solid Tumors: Providing Access and Refining Patient Selection

Authors: Geurts, Birgit

DOI: https://dspace.library.uu.nl/handle/1874/454625

Thesis

Optimización del beneficio clínico en pacientes con tumores sólidos avanzados tratados en ensayos clínicos precoces a través del desarrollo de una herramienta pronóstica online y caracterización del patrón de respuesta hiperprogresor

Matos Garcia, Ignacio · 2022

Authors: Matos Garcia, Ignacio

DOI: http://hdl.handle.net/10803/675020

Thesis

Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Verbrugge, I; Galli, M; Smyth, MJ et al. · 2021

Full title: Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Authors: Verbrugge, I; Galli, M; Smyth, MJ; Johnstone, RW; Haynes, NM

DOI: https://hdl.handle.net/11343/265284

Thesis

Inhibició de la via de la MAPK i efectes perifèrics de la inhibició dels moduladors immunes en melanoma metastàtic

Robert i Faja, Lídia · 2016

Full title: Inhibició de la via de la MAPK i efectes perifèrics de la inhibició dels moduladors immunes en melanoma metastàtic

Authors: Robert i Faja, Lídia

DOI: http://hdl.handle.net/10803/377432

Thesis

The interplay between the microbiome and colonic immune system in checkpoint inhibitor therapy

Dehinsilu, Jacob; Sergaki, Chrysi; Amos, Gregory et al. · 2023

Full title: The interplay between the microbiome and colonic immune system in checkpoint inhibitor therapy

Authors: Dehinsilu, Jacob; Sergaki, Chrysi; Amos, Gregory; Fontana, Vanessa; Pirmohamed, Munir

DOI: https://livrepository.liverpool.ac.uk/3168737/1/frmbi-02-1061193.pdf

Thesis

Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Lim, SY; Lee, JH; Welsh, SJ et al. · 2017

Full title: Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Authors: Lim, SY; Lee, JH; Welsh, SJ; Ahn, SB; Breen, E; Khan, A ; https://orcid.org/0000-0002-5072-378X; Carlino, MS; Menzies, AM; Kefford, RF; Scolyer, RA; Long, GV; Rizos, H

DOI: http://hdl.handle.net/1959.4/unsworks_79785

Thesis

T Cell-Intrinsic 4-1BB Signaling Regulates Tumor-Infiltrating CD8+ T Cell Accumulation and Response to Immunotherapy

Horton, Brendan Leigh · 2019

Full title: T Cell-Intrinsic 4-1BB Signaling Regulates Tumor-Infiltrating CD8+ T Cell Accumulation and Response to Immunotherapy

Authors: Horton, Brendan Leigh

DOI: https://knowledge.uchicago.edu/record/1562/files/Horton_uchicago_0330D_14074.pdf

Thesis

Biomarcadores para predição de resposta terapêutica a inibidores de checkpoint imunológico no câncer de pulmão : uma análise exploratória

Viola, Guilherme Danielski · 2022

Full title: Biomarcadores para predição de resposta terapêutica a inibidores de checkpoint imunológico no câncer de pulmão : uma análise exploratória

Authors: Viola, Guilherme Danielski

DOI: http://hdl.handle.net/10183/250253

Thesis

Gut microbiome and immune checkpoint inhibitor toxicity

Verheijden, Rik J; van Eijs, Mick J M; Paganelli, Fernanda L et al. · 2025

Full title: Gut microbiome and immune checkpoint inhibitor toxicity

DOI: https://dspace.library.uu.nl/handle/1874/460104

Thesis

Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Verheijden, Rik J; May, Anne M; Blank, Christian U et al. · 2020

Full title: Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

DOI: https://dspace.library.uu.nl/handle/1874/396657

Thesis

Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Chew, HY; Dolcetti, R; Simpson, F · 2021

Full title: Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Authors: Chew, HY; Dolcetti, R; Simpson, F

DOI: https://hdl.handle.net/11343/275929

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Evidence For Pd 1 Pd L1 Combination Immunotherapie

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