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Autophagy Enhancing Therapeutics For Neurodegenera

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1167 papers 694 patents 524 theses

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Paper BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease

Li, Yue; Zheng, Wanqing; Lu, Yangyang et al. · 2021 · Cell Death and Disease · DOI

Full title: BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease

Authors: Li, Yue; Zheng, Wanqing; Lu, Yangyang; Zheng, Yanrong; Pan, Ling; Wu, Xiaoli; Yuan, Yang; Shen, Zhe; Ma, Shijia; Zhang, Xingxian; Wu, Jiaying; Chen, Zhong; Zhang, Xiangnan

Year: 2021

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-021-04469-y

Paper FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.

Zhou, Kailiang; Chen, Huanwen; Lin, Jinti et al. · 2019 · Cell death & disease · DOI

Full title: FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.

Authors: Zhou, Kailiang; Chen, Huanwen; Lin, Jinti; Xu, Hui; Wu, Hongqiang; Bao, Guodong; Li, Jiafeng; Deng, Xiangyang; Shui, Xiaolong; Gao, Weiyang; Ding, Jian; Xiao, Jian; Xu, Huazi

Year: 2019

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-019-2105-0

Paper Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction.

Xu, Jianye; Zhang, Jian; Zhang, Zongpu et al. · 2021 · Cell death & disease · DOI

Full title: Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction.

Authors: Xu, Jianye; Zhang, Jian; Zhang, Zongpu; Gao, Zijie; Qi, Yanhua; Qiu, Wei; Pan, Ziwen; Guo, Qindong; Li, Boyan; Zhao, Shulin; Guo, Xiaofan; Qian, Mingyu; Chen, Zihang; Wang, Shaobo; Gao, Xiao; Zhang, Shouji; Wang, Huizhi; Guo, Xing; Zhang, Ping; Zhao, Rongrong; Xue, Hao; Li, Gang

Year: 2021

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-021-03664-1

Paper SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy.

Ma, Chengxiao; Zhang, Wen; Wang, Wengcong et al. · 2021 · Cell death & disease · DOI

Full title: SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy.

Authors: Ma, Chengxiao; Zhang, Wen; Wang, Wengcong; Shen, Jiabing; Cai, Kefu; Liu, Mei; Cao, Maohong

Year: 2021

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-021-03967-3

Paper NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma.

Huang, Xi; Cao, Wen; Yao, Shunnan et al. · 2022 · Cell death & disease · DOI

Full title: NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma.

Authors: Huang, Xi; Cao, Wen; Yao, Shunnan; Chen, Jing; Liu, Yang; Qu, Jianwei; Li, Yi; Han, Xiaoyan; He, Jingsong; Huang, He; Zhang, Enfan; Cai, Zhen

Year: 2022

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-022-04629-8

Paper ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

Ajoolabady, Amir; Lindholm, Dan; Ren, Jun et al. · 2022 · Cell Death and Disease · DOI

Full title: ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

Authors: Ajoolabady, Amir; Lindholm, Dan; Ren, Jun; Praticò, Domenico

Year: 2022

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-022-05153-5

Paper Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways

Xie, Zhen; Zhao, Mengyuan; Yan, Chengxiang et al. · 2023 · Cell Death and Disease · DOI

Full title: Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways

Authors: Xie, Zhen; Zhao, Mengyuan; Yan, Chengxiang; Kong, Wei; Lan, Fei; Narengaowa; Zhao, Shuxuan; Yang, Qinghu; Bai, Zhan‐Tao; Qing, Hong; Ni, Junjun

Year: 2023

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-023-05786-0

Paper Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death.

Depierre, Pauline; Ginet, Vanessa; Truttmann, Anita C et al. · 2024 · Cell death & disease · DOI

Full title: Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death.

Authors: Depierre, Pauline; Ginet, Vanessa; Truttmann, Anita C; Puyal, Julien

Year: 2024

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-024-06750-2

Paper CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.

Wang, Di; Li, Yongge; Chang, Weilong et al. · 2024 · Cell death & disease · DOI

Full title: CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.

Authors: Wang, Di; Li, Yongge; Chang, Weilong; Feng, Meina; Yang, Yiming; Zhu, Xiuxiang; Liu, Zhibo; Fu, Yang

Year: 2024

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-024-07057-y

Paper Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases.

Zhang, Weihuang; Li, Xiaoyu; Wang, Shujun et al. · 2020 · Cell death discovery · DOI

Full title: Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases.

Authors: Zhang, Weihuang; Li, Xiaoyu; Wang, Shujun; Chen, Yanse; Liu, Huafeng

Year: 2020

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-020-0265-4

Paper Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.

Wang, Xin; Dong, Feng-Lin; Wang, Ying-Qiao et al. · 2023 · Cell death & disease · DOI

Full title: Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.

Authors: Wang, Xin; Dong, Feng-Lin; Wang, Ying-Qiao; Wei, Hong-Long; Li, Tao; Li, Jie

Year: 2023

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-023-05989-5

Paper Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during aging.

Liu, Rui; Cui, Juanjuan; Sun, Yating et al. · 2021 · Cell death discovery · DOI

Full title: Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during aging.

Authors: Liu, Rui; Cui, Juanjuan; Sun, Yating; Xu, Wentao; Wang, Ziming; Wu, Miaomiao; Dong, Huke; Yang, Congcong; Hong, Shaocheng; Yin, Shi; Wang, Hua

Year: 2021

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-021-00797-2

Paper LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis.

Luo, Chao; Wei, Lun; Qian, Fei et al. · 2024 · Cell death discovery · DOI

Full title: LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis.

Authors: Luo, Chao; Wei, Lun; Qian, Fei; Bo, Le; Gao, Shasha; Yang, Guangzhao; Mao, Caiping

Year: 2024

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-024-01811-z

Paper Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice.

Li, Na; Chen, Lu; Zhao, Xiaoqing et al. · 2023 · Cell death discovery · DOI

Full title: Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice.

Authors: Li, Na; Chen, Lu; Zhao, Xiaoqing; Gu, Chi; Chang, Yong; Feng, Shiqing

Year: 2023

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-023-01612-w

Paper PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3.

Hou, Zixin; Chen, Ji; Yang, Huan et al. · 2021 · Cell death discovery · DOI

Full title: PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3.

Authors: Hou, Zixin; Chen, Ji; Yang, Huan; Hu, Xiaoling; Yang, Fengrui

Year: 2021

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-021-00765-w

Paper Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma.

Satriano, Andrea; Martucci, Alessio; Adornetto, Annagrazia et al. · 2025 · Cell death discovery · DOI

Full title: Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma.

Authors: Satriano, Andrea; Martucci, Alessio; Adornetto, Annagrazia; Benfatto, Elisabetta; Tettamanti, Gianluca; Bruno, Daniele; Corasaniti, Maria Tiziana; Bagetta, Giacinto; Nucci, Carlo; Russo, Rossella

Year: 2025

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-025-02824-y

Paper Degradation of lipid droplets by chimeric autophagy-tethering compounds

Fu, Yuhua; Chen, Ningxie; Wang, Ziying et al. · 2021 · Cell Research · DOI

Full title: Degradation of lipid droplets by chimeric autophagy-tethering compounds

Authors: Fu, Yuhua; Chen, Ningxie; Wang, Ziying; Luo, Shouqing; Ding, Yu; Lu, Boxun

Year: 2021

Venue: Cell Research

DOI: https://doi.org/10.1038/s41422-021-00532-7

Paper Leucine regulates autophagy via acetylation of the mTORC1 component raptor.

Son, Sung Min; Park, So Jung; Stamatakou, Eleanna et al. · 2020 · Nature communications · DOI

Full title: Leucine regulates autophagy via acetylation of the mTORC1 component raptor.

Authors: Son, Sung Min; Park, So Jung; Stamatakou, Eleanna; Vicinanza, Mariella; Menzies, Fiona M; Rubinsztein, David C

Year: 2020

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-020-16886-2

Paper Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy.

Ban, Weiyue; Sun, Mengchi; Huang, Hanwei et al. · 2023 · Nature communications · DOI

Full title: Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy.

Authors: Ban, Weiyue; Sun, Mengchi; Huang, Hanwei; Huang, Wanxu; Pan, Siwei; Liu, Pengfei; Li, Bingwu; Cheng, Zhenguo; He, Zhonggui; Liu, Funan; Sun, Jin

Year: 2023

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-023-38679-z

Paper Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability.

Katz, Maximiliano J; Rodríguez, Felipe; Evangelisti, Fermín et al. · 2025 · Nature communications · DOI

Full title: Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability.

Authors: Katz, Maximiliano J; Rodríguez, Felipe; Evangelisti, Fermín; Borrat, Agustina G; Perez-Pandolfo, Sebastián; Peters, Tomás; Sommario, Natalia; Boccaccio, Graciela L; Melani, Mariana; Wappner, Pablo

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-58389-y

Paper Enhancing autophagy by redox regulation extends lifespan in Drosophila.

Lennicke, Claudia; Bjedov, Ivana; Grönke, Sebastian et al. · 2025 · Nature communications · DOI

Full title: Enhancing autophagy by redox regulation extends lifespan in Drosophila.

Authors: Lennicke, Claudia; Bjedov, Ivana; Grönke, Sebastian; Menger, Katja E; James, Andrew M; Castillo-Quan, Jorge Iván; van Leeuwen, Lucie A G; Foley, Andrea; Buricova, Marcela; Adcott, Jennifer; Montoya, Alex; Kramer, Holger B; Shliaha, Pavel V; Logan, Angela; Cabreiro, Filipe; Murphy, Michael P; Partridge, Linda; Cochemé, Helena M

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-60603-w

Paper Machine learning identifies candidates for drug repurposing in Alzheimer’s disease

Rodriguez, Steve; Hug, Clemens B.; Todorov, Petar V. et al. · 2021 · Nature Communications · DOI

Full title: Machine learning identifies candidates for drug repurposing in Alzheimer’s disease

Authors: Rodriguez, Steve; Hug, Clemens B.; Todorov, Petar V.; Moret, Nienke; Boswell, Sarah A.; Evans, Kyle E.; Zhou, George; Johnson, Nathan; Hyman, Bradley T.; Sorger, Peter K.; Albers, Mark W.; Sokolov, Artem

Year: 2021

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-021-21330-0

Paper Autophagy formation, microtubule disorientation, and alteration of ATG8 and tubulin gene expression under simulated microgravity in Arabidopsis thaliana.

Yemets, Alla; Shadrina, Ruslana; Blume, Rostyslav et al. · 2024 · NPJ microgravity · DOI

Full title: Autophagy formation, microtubule disorientation, and alteration of ATG8 and tubulin gene expression under simulated microgravity in Arabidopsis thaliana.

Authors: Yemets, Alla; Shadrina, Ruslana; Blume, Rostyslav; Plokhovska, Svitlana; Blume, Yaroslav

Year: 2024

Venue: NPJ microgravity

DOI: https://doi.org/10.1038/s41526-024-00381-9

Paper From discoveries in ageing research to therapeutics for healthy ageing

Campisi, Judith; Kapahi, Pankaj; Lithgow, Gordon J. et al. · 2019 · Nature · DOI

Full title: From discoveries in ageing research to therapeutics for healthy ageing

Authors: Campisi, Judith; Kapahi, Pankaj; Lithgow, Gordon J.; Melov, Simon; Newman, John C.; Verdin, Eric

Year: 2019

Venue: Nature

DOI: https://doi.org/10.1038/s41586-019-1365-2

Paper Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

Bonfili, Laura; Cecarini, Valentina; Berardi, Sara et al. · 2017 · Scientific Reports · DOI

Full title: Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

Authors: Bonfili, Laura; Cecarini, Valentina; Berardi, Sara; Scarpona, Silvia; Suchodolski, Jan S.; Nasuti, Cinzia; Fiorini, Dennis; Boarelli, Maria Chiara; Rossi, Giacomo; Eleuteri, Anna Maria

Year: 2017

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-02587-2

Paper TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia

Archbold, Hilary C.; Jackson, Kasey L.; Arora, Ayush et al. · 2018 · Scientific Reports · DOI

Full title: TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia

Authors: Archbold, Hilary C.; Jackson, Kasey L.; Arora, Ayush; Weskamp, Kaitlin; Tank, Elizabeth M.H.; Li, Xingli; Miguez, Roberto; Dayton, Robert D.; Tamir, Sharon; Klein, Ronald L.; Barmada, Sami J.

Year: 2018

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-018-22858-w

Paper Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation

Rodriguez, Myosotys; Lapierre, Jessica; Ojha, Chet Raj et al. · 2017 · Scientific Reports · DOI

Full title: Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation

Authors: Rodriguez, Myosotys; Lapierre, Jessica; Ojha, Chet Raj; Kaushik, Ajeet; Batrakova, Elena V.; Kashanchi, Fatah; Dever, Seth M.; Nair, Madhavan; El‐Hage, Nazira

Year: 2017

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-01819-9

Paper Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuronal cells.

Seo, Seung-Hwan; Ham, Do-Won; Lee, Ji-Eun et al. · 2025 · Scientific reports · DOI

Full title: Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuronal cells.

Authors: Seo, Seung-Hwan; Ham, Do-Won; Lee, Ji-Eun; Shin, Eun-Hee

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-00271-4

Paper Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

Chriett, Sabrina; Dąbek, Arkadiusz; Wojtala, Martyna et al. · 2019 · Scientific Reports · DOI

Full title: Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

Authors: Chriett, Sabrina; Dąbek, Arkadiusz; Wojtala, Martyna; Vidal, Hubert; Balcerczyk, Aneta; Pirola, Luciano

Year: 2019

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-018-36941-9

Paper Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer cells.

Meng, Xiang-Yu; Li, Yi; Yan, Ze-Jun et al. · 2025 · Scientific reports · DOI

Full title: Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer cells.

Authors: Meng, Xiang-Yu; Li, Yi; Yan, Ze-Jun; Ye, Sha-Zhou; Wang, Ke-Jie; Chen, Jun-Feng; Yu, Rui; Ma, Qi

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-00909-3

Paper 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.

Singhal, Ashutosh; Krystofiak, Evan S; Jerome, W Gray et al. · 2020 · Scientific reports · DOI

Full title: 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.

Authors: Singhal, Ashutosh; Krystofiak, Evan S; Jerome, W Gray; Song, Byeongwoon

Year: 2020

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-020-65627-4

Paper HMGB1 mediated autophagy and apoptosis in human nucleus pulposus cells; chloroquine amplified apoptosis by inhibiting autophagy.

Khaleque, Md Abdul; Kim, Ga-Hyun; Kim, Do-Kyun et al. · 2025 · Scientific reports · DOI

Full title: HMGB1 mediated autophagy and apoptosis in human nucleus pulposus cells; chloroquine amplified apoptosis by inhibiting autophagy.

Authors: Khaleque, Md Abdul; Kim, Ga-Hyun; Kim, Do-Kyun; Tanvir, Md Amit Hasan; Lee, Hwan-Hee; Kim, Young-Yul

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-23026-7

Paper Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.

Li, Ying; Zhao, Helian; Shen, Zhoumin et al. · 2024 · Scientific reports · DOI

Full title: Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.

Authors: Li, Ying; Zhao, Helian; Shen, Zhoumin; Zheng, Yao; Jiang, Yuanyuan; Song, Ying; Cai, Yimin

Year: 2024

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-024-73736-7

Paper Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

Agu, Peter Chinedu; Afiukwa, Celestine Azubuike; Orji, O.U. et al. · 2023 · Scientific Reports · DOI

Full title: Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

Authors: Agu, Peter Chinedu; Afiukwa, Celestine Azubuike; Orji, O.U.; Ezeh, Ernest Mbamalu; Ofoke, Ifeanyi Harrison; Ogbu, Cyprian O.; Ugwuja, Emmanuel Ike; Aja, Patrick Maduabuchi

Year: 2023

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-023-40160-2

Paper Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures.

Ivanov, Vladimir N; Grabham, Peter W; Wu, Cheng-Chia et al. · 2020 · Scientific reports · DOI

Full title: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures.

Authors: Ivanov, Vladimir N; Grabham, Peter W; Wu, Cheng-Chia; Hei, Tom K

Year: 2020

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-020-59468-4

Paper The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer

Cufí, Sílvia; Vázquez‐Martín, Alejandro; Oliveras‐Ferraros, Cristina et al. · 2013 · Scientific Reports · DOI

Full title: The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer

Authors: Cufí, Sílvia; Vázquez‐Martín, Alejandro; Oliveras‐Ferraros, Cristina; Corominas-Faja, Bruna; Cuyàs, Elisabet; López‐Bonet, Eugeni; Martı́n-Castillo, Begoña; Joven, Jorge; Menéndez, Javier A.

Year: 2013

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep02469

Paper Two specific interactions of GATE16 with TRPML3 and RAB33B regulate autophagy.

Park, Jiwoo; Choi, Areum; Kwon, Jin et al. · 2025 · Scientific reports · DOI

Full title: Two specific interactions of GATE16 with TRPML3 and RAB33B regulate autophagy.

Authors: Park, Jiwoo; Choi, Areum; Kwon, Jin; Choi, Suzi; Park, Yun Min; Kim, Hyun Jin

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-16951-0

Paper Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models.

Cui, Jing; Bai, Xue-Yuan; Sun, Xuefeng et al. · 2015 · Scientific reports · DOI

Full title: Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models.

Authors: Cui, Jing; Bai, Xue-Yuan; Sun, Xuefeng; Cai, Guangyan; Hong, Quan; Ding, Rui; Chen, Xiangmei

Year: 2015

Venue: Scientific reports

DOI: https://doi.org/10.1038/srep11256

Paper Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mitochondrial disruption.

Lu, Ping; Xue, Juan; Ji, Xuemeng · 2025 · Scientific reports · DOI

Full title: Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mitochondrial disruption.

Authors: Lu, Ping; Xue, Juan; Ji, Xuemeng

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-05008-x

Paper Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes.

Vélez, Emilio J; Véron, Vincent; Gouis, Jeanne et al. · 2025 · Scientific reports · DOI

Full title: Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes.

Authors: Vélez, Emilio J; Véron, Vincent; Gouis, Jeanne; Reji, Steffi; Dias, Karine; Herpin, Amaury; Beaumatin, Florian; Seiliez, Iban

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-23022-x

Paper Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition

Subramani, Ramadevi; Gonzalez, Elizabeth M.; Arumugam, Arunkumar et al. · 2016 · Scientific Reports · DOI

Full title: Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition

Authors: Subramani, Ramadevi; Gonzalez, Elizabeth M.; Arumugam, Arunkumar; Nandy, Sushmita; Gonzalez, Viviana; Medel, Joshua; Camacho, Fernando; Ortega, Andrew; Bonkoungou, Sandrine; Narayan, Mahesh; Dwivedi, Alok; Lakshmanaswamy, Rajkumar

Year: 2016

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep19819

Paper The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.

Kovács, Tibor; Billes, Viktor; Komlós, Marcell et al. · 2017 · Scientific reports · DOI

Full title: The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.

Authors: Kovács, Tibor; Billes, Viktor; Komlós, Marcell; Hotzi, Bernadette; Manzéger, Anna; Tarnóci, Anna; Papp, Diána; Szikszai, Fanni; Szinyákovics, Janka; Rácz, Ákos; Noszál, Béla; Veszelka, Szilvia; Walter, Fruzsina R; Deli, Mária A; Hackler, Laszlo; Alfoldi, Robert; Huzian, Orsolya; Puskas, Laszlo G; Liliom, Hanna; Tárnok, Krisztián; Schlett, Katalin; Borsy, Adrienn; Welker, Ervin; Kovács, Attila L; Pádár, Zsolt; Erdős, Attila; Legradi, Adam; Bjelik, Annamaria; Gulya, Károly; Gulyás, Balázs; Vellai, Tibor

Year: 2017

Venue: Scientific reports

DOI: https://doi.org/10.1038/srep42014

Paper The germline-enriched Ppp1r36 promotes autophagy.

Zhang, Qinghua; Gao, Maomao; Zhang, Ying et al. · 2016 · Scientific reports · DOI

Full title: The germline-enriched Ppp1r36 promotes autophagy.

Authors: Zhang, Qinghua; Gao, Maomao; Zhang, Ying; Song, Ying; Cheng, Hanhua; Zhou, Rongjia

Year: 2016

Venue: Scientific reports

DOI: https://doi.org/10.1038/srep24609

Paper Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells.

Yang, Jianhong; Zhou, Yongzhao; Cheng, Xia et al. · 2015 · Scientific reports · DOI

Full title: Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells.

Authors: Yang, Jianhong; Zhou, Yongzhao; Cheng, Xia; Fan, Yi; He, Shichao; Li, Shucai; Ye, Haoyu; Xie, Caifeng; Wu, Wenshuang; Li, Chunyan; Pei, Heying; Li, Luyuan; Wei, Zhe; Peng, Aihua; Wei, Yuquan; Li, Weimin; Chen, Lijuan

Year: 2015

Venue: Scientific reports

DOI: https://doi.org/10.1038/srep07697

Paper Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha‐1‐anti‐trypsin deficiency

Pastore, Nunzia; Blomenkamp, Keith; Annunziata, Fabio et al. · 2013 · EMBO Molecular Medicine · DOI

Full title: Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha‐1‐anti‐trypsin deficiency

Authors: Pastore, Nunzia; Blomenkamp, Keith; Annunziata, Fabio; Piccolo, Pasquale; Mithbaokar, Pratibha; Sepe, Rosa Maria; Vetrini, Francesco; Palmer, Donna; Ng, Kin Cheung; Polishchuk, Elena; Iacobacci, Simona; Polishchuk, Roman; Teckman, Jeffrey; Ballabio, Andrea; Brunetti‐Pierri, Nicola

Year: 2013

Venue: EMBO Molecular Medicine

DOI: https://doi.org/10.1002/emmm.201202046

Paper Exercise-derived peptide confers protection against septic cardiomyopathy by enhancing CCAAT/enhancer binding protein β-mediated autophagy.

Huang, Xiying; Xu, Ke; Wang, Yinghua et al. · 2025 · Cellular and molecular life sciences : CMLS · DOI

Full title: Exercise-derived peptide confers protection against septic cardiomyopathy by enhancing CCAAT/enhancer binding protein β-mediated autophagy.

Authors: Huang, Xiying; Xu, Ke; Wang, Yinghua; Xiao, Qingqing; Ci, Hongfei; Fu, Xi; Li, Yi; Zhuang, Fei; Cai, Zhaohua; Zhou, Guo; Huo, Huanhuan; He, Ben; Wang, Xia; Shen, Linghong

Year: 2025

Venue: Cellular and molecular life sciences : CMLS

DOI: https://doi.org/10.1007/s00018-025-05949-6

Paper The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing.

Chau, Dennis Dik-Long; Yu, Zhicheng; Chan, Wai Wa Ray et al. · 2024 · Cellular and molecular life sciences : CMLS · DOI

Full title: The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing.

Authors: Chau, Dennis Dik-Long; Yu, Zhicheng; Chan, Wai Wa Ray; Yuqi, Zhai; Chang, Raymond Chuen Chung; Ngo, Jacky Chi Ki; Chan, Ho Yin Edwin; Lau, Kwok-Fai

Year: 2024

Venue: Cellular and molecular life sciences : CMLS

DOI: https://doi.org/10.1007/s00018-024-05351-8

Paper N4-acetylcytidine-mediated SOAT1 upregulation aggravates heart failure by inducing NCOA4-dependent ferroautophagy and ferroptosis in cardiomyocytes.

Deng, Jizhao; Nong, Xiting; Yang, Guang · 2025 · Cellular and molecular life sciences : CMLS · DOI

Full title: N4-acetylcytidine-mediated SOAT1 upregulation aggravates heart failure by inducing NCOA4-dependent ferroautophagy and ferroptosis in cardiomyocytes.

Authors: Deng, Jizhao; Nong, Xiting; Yang, Guang

Year: 2025

Venue: Cellular and molecular life sciences : CMLS

DOI: https://doi.org/10.1007/s00018-025-05932-1

Paper Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin

Tuli, Hardeep Singh; Sandhu, Sardul Singh; Sharma, Anil Kumar · 2013 · 3 Biotech · DOI

Full title: Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin

Authors: Tuli, Hardeep Singh; Sandhu, Sardul Singh; Sharma, Anil Kumar

Year: 2013

Venue: 3 Biotech

DOI: https://doi.org/10.1007/s13205-013-0121-9

Paper Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment.

Xiao, Yuhuan; Fu, Xiaofeng; Zhou, Weina et al. · 2026 · Tissue engineering and regenerative medicine · DOI

Full title: Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment.

Authors: Xiao, Yuhuan; Fu, Xiaofeng; Zhou, Weina; Li, Jin; Yan, Bin; Jiang, Fei

Year: 2026

Venue: Tissue engineering and regenerative medicine

DOI: https://doi.org/10.1007/s13770-025-00789-8

Paper Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity.

Wan, Jia-Jia; Yin, Qiu-Yuan; Sun, Mao et al. · 2025 · Natural products and bioprospecting · DOI

Full title: Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity.

Authors: Wan, Jia-Jia; Yin, Qiu-Yuan; Sun, Mao; Zhang, Cui-Shan; Zang, Hao-Jing; Yao, Pei-Tong; Yuan, Ming-Rui; Chen, Ding-Kang; Guo, Feng; Chen, Qun; Ouyang, Bo-Wen; Xu, Zi-Fei; Cao, Ming-Ming; Yang, Chong-Lin; Hao, Xiao-Jiang; Di, Ying-Tong

Year: 2025

Venue: Natural products and bioprospecting

DOI: https://doi.org/10.1007/s13659-025-00522-x

Paper Role of autophagy in neurotoxic protein's clearance following post-ischemic stroke: where we are and what we know?

Kazmi, Sareh; Farokhi-Sisakht, Fatemeh; Davoody, Samin et al. · 2025 · Molecular brain · DOI

Full title: Role of autophagy in neurotoxic protein's clearance following post-ischemic stroke: where we are and what we know?

Authors: Kazmi, Sareh; Farokhi-Sisakht, Fatemeh; Davoody, Samin; Bahlakeh, Gozal; Abbaszadeh, Fatemeh; Rahbarghazi, Reza; Shekarchi, Aliakbar; Karimipour, Mohammad

Year: 2025

Venue: Molecular brain

DOI: https://doi.org/10.1186/s13041-025-01201-1

Paper Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?

Gunst, Jan; Casaer, Michael P; Preiser, Jean-Charles et al. · 2023 · Critical care (London, England) · DOI

Full title: Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?

Authors: Gunst, Jan; Casaer, Michael P; Preiser, Jean-Charles; Reignier, Jean; Van den Berghe, Greet

Year: 2023

Venue: Critical care (London, England)

DOI: https://doi.org/10.1186/s13054-023-04317-9

Paper Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy.

Hu, Bingbing; Zheng, Xiushuang; Zhang, Wei · 2024 · Journal of ovarian research · DOI

Full title: Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy.

Authors: Hu, Bingbing; Zheng, Xiushuang; Zhang, Wei

Year: 2024

Venue: Journal of ovarian research

DOI: https://doi.org/10.1186/s13048-024-01344-0

Paper YAP promotes autophagy and progression of gliomas via upregulating HMGB1.

Zhao, Min; Zhang, Yu; Jiang, Yang et al. · 2021 · Journal of experimental & clinical cancer research : CR · DOI

Full title: YAP promotes autophagy and progression of gliomas via upregulating HMGB1.

Authors: Zhao, Min; Zhang, Yu; Jiang, Yang; Wang, Kai; Wang, Xiang; Zhou, Ding; Wang, Yan; Yu, Rutong; Zhou, Xiuping

Year: 2021

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-021-01897-8

Paper CircCEMIP promotes anoikis-resistance by enhancing protective autophagy in prostate cancer cells.

Yu, Ying; Song, Yarong; Cheng, Lulin et al. · 2022 · Journal of experimental & clinical cancer research : CR · DOI

Full title: CircCEMIP promotes anoikis-resistance by enhancing protective autophagy in prostate cancer cells.

Authors: Yu, Ying; Song, Yarong; Cheng, Lulin; Chen, Liang; Liu, Bing; Lu, Dingheng; Li, Xuexiang; Li, Yunxue; Lv, Fang; Xing, Yifei

Year: 2022

Venue: Journal of experimental & clinical cancer research : CR

DOI: https://doi.org/10.1186/s13046-022-02381-7

Paper Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.

Chen, Yanxing; Zhao, Shuai; Fan, Ziqi et al. · 2021 · Alzheimer's research & therapy · DOI

Full title: Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.

Authors: Chen, Yanxing; Zhao, Shuai; Fan, Ziqi; Li, Zheyu; Zhu, Yueli; Shen, Ting; Li, Kaicheng; Yan, Yaping; Tian, Jun; Liu, Zhirong; Zhang, Baorong

Year: 2021

Venue: Alzheimer's research & therapy

DOI: https://doi.org/10.1186/s13195-020-00761-9

Paper Modulation of PI3K/AKT/mTOR signaling pathway by combined stem cell and phytochemical treatment improves metabolic and reproductive outcomes in PCOS.

Chen, Jixiang; Zhang, Lihua; Gan, Junhong et al. · 2025 · Journal of ovarian research · DOI

Full title: Modulation of PI3K/AKT/mTOR signaling pathway by combined stem cell and phytochemical treatment improves metabolic and reproductive outcomes in PCOS.

Authors: Chen, Jixiang; Zhang, Lihua; Gan, Junhong; Teng, Xueyan; Huang, Xiaohong; Lv, Jinliu; Li, Hao

Year: 2025

Venue: Journal of ovarian research

DOI: https://doi.org/10.1186/s13048-025-01910-0

Paper Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy.

Xu, Yuan-Qiao; Chen, Yanjiao; Xing, Jia-Xin et al. · 2025 · Clinical epigenetics · DOI

Full title: Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy.

Authors: Xu, Yuan-Qiao; Chen, Yanjiao; Xing, Jia-Xin; Yao, Jun

Year: 2025

Venue: Clinical epigenetics

DOI: https://doi.org/10.1186/s13148-025-01820-4

Paper Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells

Min, Ahrum; Im, Seock‐Ah; Kim, Debora Keunyoung et al. · 2015 · Breast Cancer Research · DOI

Full title: Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells

Authors: Min, Ahrum; Im, Seock‐Ah; Kim, Debora Keunyoung; Song, Sang-Hyun; Kim, Hee Jun; Lee, Kyung-Hun; Kim, Tae‐Yong; Han, Sae‐Won; Oh, Do‐Youn; Kim, Tae‐You; O’Connor, Mark J.; Bang, Yung‐Jue

Year: 2015

Venue: Breast Cancer Research

DOI: https://doi.org/10.1186/s13058-015-0534-y

Paper Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

Lim, Su Min; Hanif, Ezanee Azlina Mohamad; Chin, Siok‐Fong · 2021 · Cell & Bioscience · DOI

Full title: Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

Authors: Lim, Su Min; Hanif, Ezanee Azlina Mohamad; Chin, Siok‐Fong

Year: 2021

Venue: Cell & Bioscience

DOI: https://doi.org/10.1186/s13578-021-00570-z

Paper Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy.

Zhang, Rui; Huang, Lei; Jin, Meng et al. · 2025 · Stem cell research & therapy · DOI

Full title: Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy.

Authors: Zhang, Rui; Huang, Lei; Jin, Meng; Kou, Haiyang; Ma, Jie; Zhang, Weijie; Ma, Jianbing

Year: 2025

Venue: Stem cell research & therapy

DOI: https://doi.org/10.1186/s13287-025-04836-y

Paper Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.

Ma, Zhida; Meng, Congpeng; Wang, Xiang et al. · 2025 · Cell & bioscience · DOI

Full title: Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.

Authors: Ma, Zhida; Meng, Congpeng; Wang, Xiang; Zhao, Yuanzhe; Wang, Jingwen; Chen, Yihao; Li, Yiteng; Jiang, Yan; Ouyang, Fangru; Li, Jianjian; Zheng, Meige; Cheng, Li; Jing, Juehua

Year: 2025

Venue: Cell & bioscience

DOI: https://doi.org/10.1186/s13578-025-01357-2

Paper Exosomes: biogenesis, biologic function and clinical potential

Zhang, Yuan; Liu, Yunfeng; Liu, Haiying et al. · 2019 · Cell & Bioscience · DOI

Full title: Exosomes: biogenesis, biologic function and clinical potential

Authors: Zhang, Yuan; Liu, Yunfeng; Liu, Haiying; Tang, Wai Ho

Year: 2019

Venue: Cell & Bioscience

DOI: https://doi.org/10.1186/s13578-019-0282-2

Paper Quercetin improves myocardial ischemia-reperfusion injury by regulating macrophage M2 polarization through Bcl-2/Beclin-1 complex.

Hu, Sailing; Lv, Lingchun; Hu, Wuming et al. · 2025 · European journal of medical research · DOI

Full title: Quercetin improves myocardial ischemia-reperfusion injury by regulating macrophage M2 polarization through Bcl-2/Beclin-1 complex.

Authors: Hu, Sailing; Lv, Lingchun; Hu, Wuming; Shen, Jiayi

Year: 2025

Venue: European journal of medical research

DOI: https://doi.org/10.1186/s40001-025-03077-2

Paper Growth differentiation factor 11 alleviates oxidative stress-induced senescence of endothelial progenitor cells via activating autophagy.

Tao, Ping; Zhang, Hai-Feng; Zhou, Pei et al. · 2024 · Stem cell research & therapy · DOI

Full title: Growth differentiation factor 11 alleviates oxidative stress-induced senescence of endothelial progenitor cells via activating autophagy.

Authors: Tao, Ping; Zhang, Hai-Feng; Zhou, Pei; Wang, Yong-Li; Tan, Yu-Zhen; Wang, Hai-Jie

Year: 2024

Venue: Stem cell research & therapy

DOI: https://doi.org/10.1186/s13287-024-03975-y

Paper Sestrin2 in cancer: a foe or a friend?

Ala, Moein · 2022 · Biomarker research · DOI

Full title: Sestrin2 in cancer: a foe or a friend?

Authors: Ala, Moein

Year: 2022

Venue: Biomarker research

DOI: https://doi.org/10.1186/s40364-022-00380-6

Paper LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy.

Liao, Danling; Chen, Wenqu; Deng, Yuyang et al. · 2025 · Eye and vision (London, England) · DOI

Full title: LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy.

Authors: Liao, Danling; Chen, Wenqu; Deng, Yuyang; Wei, Shijia; Wang, Li; Hu, Jianzhang

Year: 2025

Venue: Eye and vision (London, England)

DOI: https://doi.org/10.1186/s40662-025-00448-y

Paper PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

Quinn, Peter M. J.; Moreira, Paula I.; Ambrósio, António Francisco et al. · 2020 · Acta Neuropathologica Communications · DOI

Full title: PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

Authors: Quinn, Peter M. J.; Moreira, Paula I.; Ambrósio, António Francisco; Alves, C. Henrique

Year: 2020

Venue: Acta Neuropathologica Communications

DOI: https://doi.org/10.1186/s40478-020-01062-w

Paper Protein misfolding in neurodegenerative diseases: implications and strategies

Sweeney, Patrick; Park, Hyunsun; Baumann, Marc et al. · 2017 · Translational Neurodegeneration · DOI

Full title: Protein misfolding in neurodegenerative diseases: implications and strategies

Authors: Sweeney, Patrick; Park, Hyunsun; Baumann, Marc; Dunlop, John; Frydman, Judith; Kopito, Ron R.; McCampbell, Alexander; Leblanc, Gabrielle G.; Venkateswaran, Anjli; Nurmi, Antti; Hodgson, Robert A.

Year: 2017

Venue: Translational Neurodegeneration

DOI: https://doi.org/10.1186/s40035-017-0077-5

Paper Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2.

Xiang, Yulan; Li, Zelu; He, Xin et al. · 2025 · Stem cell research & therapy · DOI

Full title: Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2.

Authors: Xiang, Yulan; Li, Zelu; He, Xin; Chu, Xiaoyang; Gao, Chunyan; Guo, Jiahao; Luan, Yingyi; Yang, Kai; Zhang, Dongliang

Year: 2025

Venue: Stem cell research & therapy

DOI: https://doi.org/10.1186/s13287-025-04355-w

Paper Programmed cell death and its role in inflammation

Yang, Yong; Jiang, Gening; Zhang, Peng et al. · 2015 · Military Medical Research · DOI

Full title: Programmed cell death and its role in inflammation

Authors: Yang, Yong; Jiang, Gening; Zhang, Peng; Fan, Jie

Year: 2015

Venue: Military Medical Research

DOI: https://doi.org/10.1186/s40779-015-0039-0

Paper METTL21C mediates autophagy and formation of slow-twitch muscle fibers in mice after exercise.

Qu, Jing; Dang, Shuai; Sun, Yuan-Yuan et al. · 2024 · Genes & genetic systems · DOI

Full title: METTL21C mediates autophagy and formation of slow-twitch muscle fibers in mice after exercise.

Authors: Qu, Jing; Dang, Shuai; Sun, Yuan-Yuan; Zhang, Tao; Jiang, Hai; Lu, Hong-Zhao

Year: 2024

Venue: Genes & genetic systems

DOI: https://doi.org/10.1266/ggs.23-00320

Paper Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice.

Zhang, Denghui; Zhu, Tianer; Bai, Jingyao et al. · 2025 · Bone & joint research · DOI

Full title: Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice.

Authors: Zhang, Denghui; Zhu, Tianer; Bai, Jingyao; Chen, Chunchun; Wen, Junru; Zhou, Yi; Guan, Xiaoxu

Year: 2025

Venue: Bone & joint research

DOI: https://doi.org/10.1302/2046-3758.142.BJR-2024-0112.R2

Paper Sodium Orthovanadate Mitigates Nonalcoholic Fatty Liver Disease by Enhancing Autophagy.

Zhang, Xudong; Zhou, Haiyang; Kong, Zhijun et al. · 2024 · Biological & pharmaceutical bulletin · DOI

Full title: Sodium Orthovanadate Mitigates Nonalcoholic Fatty Liver Disease by Enhancing Autophagy.

Authors: Zhang, Xudong; Zhou, Haiyang; Kong, Zhijun; Li, Tao; Zhu, Chunfu; Tang, Wei; Qin, Xihu; Tang, Liming

Year: 2024

Venue: Biological & pharmaceutical bulletin

DOI: https://doi.org/10.1248/bpb.b24-00355

Paper 2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

Wang, Qilong; Liang, Bin; Shirwany, Najeeb A. et al. · 2011 · PLoS ONE · DOI

Full title: 2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

Authors: Wang, Qilong; Liang, Bin; Shirwany, Najeeb A.; Zou, Ming‐Hui

Year: 2011

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0017234

Paper Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition

Bray, Kevin; Mathew, Robin; Lau, Alexandria et al. · 2012 · PLoS ONE · DOI

Full title: Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition

Authors: Bray, Kevin; Mathew, Robin; Lau, Alexandria; Kamphorst, Jurre J.; Fan, Jing; Chen, Jim; Chen, Hsin-Yi; Ghavami, Anahita; Stein, Mark N.; DiPaola, Robert S.; Zhang, Donna; Rabinowitz, Joshua D.; White, Eileen

Year: 2012

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0041831

Paper Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification.

Ruckenstuhl, Christoph; Netzberger, Christine; Entfellner, Iryna et al. · 2014 · PLoS genetics · DOI

Full title: Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification.

Authors: Ruckenstuhl, Christoph; Netzberger, Christine; Entfellner, Iryna; Carmona-Gutierrez, Didac; Kickenweiz, Thomas; Stekovic, Slaven; Gleixner, Christina; Schmid, Christian; Klug, Lisa; Sorgo, Alice G; Eisenberg, Tobias; Büttner, Sabrina; Mariño, Guillermo; Koziel, Rafal; Jansen-Dürr, Pidder; Fröhlich, Kai-Uwe; Kroemer, Guido; Madeo, Frank

Year: 2014

Venue: PLoS genetics

DOI: https://doi.org/10.1371/journal.pgen.1004347

Paper Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

Tekedereli, İbrahim; Alpay, S. Neslihan; Tavares, Clint D.J. et al. · 2012 · PLoS ONE · DOI

Full title: Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

Authors: Tekedereli, İbrahim; Alpay, S. Neslihan; Tavares, Clint D.J.; Cobanoglu, Zehra E.; Kaoud, Tamer S.; Şahin, İbrahim Halil; Sood, Anil K.; Lopez‐Berestein, Gabriel; Dalby, Kevin N.; Özpolat, Bülent

Year: 2012

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0041171

Paper Coordinate Autophagy and mTOR Pathway Inhibition Enhances Cell Death in Melanoma

Xie, Xiaoqi; White, Eileen; Mehnert, Janice M. · 2013 · PLoS ONE · DOI

Full title: Coordinate Autophagy and mTOR Pathway Inhibition Enhances Cell Death in Melanoma

Authors: Xie, Xiaoqi; White, Eileen; Mehnert, Janice M.

Year: 2013

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0055096

Paper mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

Decuypere, Jean-Paul; Kindt, Dimphny; Luyten, Tomas et al. · 2013 · PloS one · DOI

Full title: mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

Authors: Decuypere, Jean-Paul; Kindt, Dimphny; Luyten, Tomas; Welkenhuyzen, Kirsten; Missiaen, Ludwig; De Smedt, Humbert; Bultynck, Geert; Parys, Jan B

Year: 2013

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0061020

Paper Correction: Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pathway to improve knee cartilage degeneration.

Wang, Ye-Hui; Zhou, Yi; Gao, Xiang et al. · 2024 · PloS one · DOI

Full title: Correction: Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pathway to improve knee cartilage degeneration.

Authors: Wang, Ye-Hui; Zhou, Yi; Gao, Xiang; Sun, Sheng; Xie, Yi-Zhou; Hu, You-Peng; Fu, Yang; Fan, Xiao-Hong; Xie, Quan

Year: 2024

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0306763

Paper Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration.

Lin, Yunting; Tang, Chengyuan; He, Hua et al. · 2013 · PloS one · DOI

Full title: Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration.

Authors: Lin, Yunting; Tang, Chengyuan; He, Hua; Duan, Ranhui

Year: 2013

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0062572

Paper Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

Racoma, Ira; Meisen, Walter H.; Wang, Qi‐En et al. · 2013 · PLoS ONE · DOI

Full title: Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

Authors: Racoma, Ira; Meisen, Walter H.; Wang, Qi‐En; Kaur, Balveen; Wani, Altaf A.

Year: 2013

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0072882

Paper Protective role of AMP-activated protein kinase-evoked autophagy on an in vitro model of ischemia/reperfusion-induced renal tubular cell injury.

Wang, Li-Ting; Chen, Bo-Lin; Wu, Cheng-Tien et al. · 2013 · PloS one · DOI

Full title: Protective role of AMP-activated protein kinase-evoked autophagy on an in vitro model of ischemia/reperfusion-induced renal tubular cell injury.

Authors: Wang, Li-Ting; Chen, Bo-Lin; Wu, Cheng-Tien; Huang, Kuo-How; Chiang, Chih-Kang; Hwa Liu, Shing

Year: 2013

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0079814

Paper Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects

Toledo, Françoise Wilhelmi de; Grundler, Franziska; Bergouignan, Audrey et al. · 2019 · PLoS ONE · DOI

Full title: Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects

Authors: Toledo, Françoise Wilhelmi de; Grundler, Franziska; Bergouignan, Audrey; Drinda, Stefan; Michalsen, Andreas

Year: 2019

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0209353

Paper SlATG8f modulates tomato thermotolerance and fruit quality, correlating with changes in autophagy and heat shock-related genes.

Cheng, Qunmei; Xu, Wen; Wen, Cen et al. · 2026 · PloS one · DOI

Full title: SlATG8f modulates tomato thermotolerance and fruit quality, correlating with changes in autophagy and heat shock-related genes.

Authors: Cheng, Qunmei; Xu, Wen; Wen, Cen; He, Zhuo; Song, Liu

Year: 2026

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0334005

Paper MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting Rheb.

Wang, Jinli; Yang, Kun; Zhou, Lin et al. · 2013 · PLoS pathogens · DOI

Full title: MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting Rheb.

Authors: Wang, Jinli; Yang, Kun; Zhou, Lin; Minhaowu; Wu, Yongjian; Zhu, Min; Lai, Xiaomin; Chen, Tao; Feng, Lianqiang; Li, Meiyu; Huang, Chunyu; Zhong, Qiu; Huang, Xi

Year: 2013

Venue: PLoS pathogens

DOI: https://doi.org/10.1371/journal.ppat.1003697

Paper Lutein Attenuates Both Apoptosis and Autophagy upon Cobalt (II) Chloride-Induced Hypoxia in Rat Műller Cells.

Fung, Frederic K C; Law, Betty Y K; Lo, Amy C Y · 2016 · PloS one · DOI

Full title: Lutein Attenuates Both Apoptosis and Autophagy upon Cobalt (II) Chloride-Induced Hypoxia in Rat Műller Cells.

Authors: Fung, Frederic K C; Law, Betty Y K; Lo, Amy C Y

Year: 2016

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0167828

Paper RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy.

Qian, Hongmei; Chen, Wei; Yuan, Guomei et al. · 2024 · PloS one · DOI

Full title: RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy.

Authors: Qian, Hongmei; Chen, Wei; Yuan, Guomei; Luo, Man; Zhang, Li; Wu, Biao; Huang, Hanshi; Xu, Jiahao; Wang, Qiong; Li, Mengyun

Year: 2024

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0313446

Paper Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways.

Sundvold, Hilde; Strøm, Thea Bismo · 2025 · PloS one · DOI

Full title: Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways.

Authors: Sundvold, Hilde; Strøm, Thea Bismo

Year: 2025

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0338076

Paper Mitochondria in Ischemic Stroke: New Insight and Implications

Liu, Fan; Lu, Jianfei; Manaenko, Anatol et al. · 2018 · Aging and Disease · DOI

Full title: Mitochondria in Ischemic Stroke: New Insight and Implications

Authors: Liu, Fan; Lu, Jianfei; Manaenko, Anatol; Tang, Junjia; Hu, Qin

Year: 2018

Venue: Aging and Disease

DOI: https://doi.org/10.14336/ad.2017.1126

Paper Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms.

Li, Bin; Yang, Xiao Meng; Zhou, Xiong Ming et al. · 2025 · PloS one · DOI

Full title: Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms.

Authors: Li, Bin; Yang, Xiao Meng; Zhou, Xiong Ming; Huang, Yuan Qing

Year: 2025

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0319770

Paper Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

Stanley, Sarah A.; Barczak, Amy K.; Silvis, Melanie R. et al. · 2014 · PLoS Pathogens · DOI

Full title: Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

Authors: Stanley, Sarah A.; Barczak, Amy K.; Silvis, Melanie R.; Luo, Shoukang; Sogi, Kimberly M.; Vokes, Martha S.; Bray, Mark‐Anthony; Carpenter, Anne E.; Moore, Christopher B.; Siddiqi, Noman; Rubin, Eric J.; Hung, Deborah T.

Year: 2014

Venue: PLoS Pathogens

DOI: https://doi.org/10.1371/journal.ppat.1003946

Paper The Effects of Methylene Blue on Autophagy and Apoptosis in MRI-Defined Normal Tissue, Ischemic Penumbra and Ischemic Core.

Jiang, Zhao; Watts, Lora Talley; Huang, Shiliang et al. · 2015 · PloS one · DOI

Full title: The Effects of Methylene Blue on Autophagy and Apoptosis in MRI-Defined Normal Tissue, Ischemic Penumbra and Ischemic Core.

Authors: Jiang, Zhao; Watts, Lora Talley; Huang, Shiliang; Shen, Qiang; Rodriguez, Pavel; Chen, Chunhua; Zhou, Changman; Duong, Timothy Q

Year: 2015

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0131929

Paper Acetylation dynamics of MrATG4 governing autophagy-mediated conidiation in an entomopathogenic fungus.

Yu, Deshui; Wang, Yulong; Xie, Rui et al. · 2026 · PLoS pathogens · DOI

Full title: Acetylation dynamics of MrATG4 governing autophagy-mediated conidiation in an entomopathogenic fungus.

Authors: Yu, Deshui; Wang, Yulong; Xie, Rui; Zhou, Rong; Liu, Zhenbang; Shi, Najie; Xie, Xiangyun; Yang, Yang; Qu, Jiaojiao; Yang, Guang; Huang, Bo

Year: 2026

Venue: PLoS pathogens

DOI: https://doi.org/10.1371/journal.ppat.1013883

Paper Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly.

Zang, Qun S; Wolf, Steven E; Minei, Joseph P · 2014 · Aging and disease · DOI

Full title: Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly.

Authors: Zang, Qun S; Wolf, Steven E; Minei, Joseph P

Year: 2014

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2014.0500137

Paper Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies

Onyango, Isaac G.; Dennis, Jameel; Khan, Shaharyah M. · 2016 · Aging and Disease · DOI

Full title: Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies

Authors: Onyango, Isaac G.; Dennis, Jameel; Khan, Shaharyah M.

Year: 2016

Venue: Aging and Disease

DOI: https://doi.org/10.14336/ad.2015.1007

Paper TBC1D15 Inhibits Autophagy of Microglia through Maintaining the Damaged Swelling Lysosome in Alzheimer's Disease.

Wu, You; Zhou, Yong-Ming; Wu, Wei et al. · 2024 · Aging and disease · DOI

Full title: TBC1D15 Inhibits Autophagy of Microglia through Maintaining the Damaged Swelling Lysosome in Alzheimer's Disease.

Authors: Wu, You; Zhou, Yong-Ming; Wu, Wei; Jiang, Wan-Rong; Zhang, Xin-Yuan; Song, Si-Yuan; Yao, Zhao-Hui

Year: 2024

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2024.1373

Paper Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the Aging Population.

Wang, Mingwei; Wu, Xiangzhi; Jiao, Yuyao et al. · 2024 · Aging and disease · DOI

Full title: Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the Aging Population.

Authors: Wang, Mingwei; Wu, Xiangzhi; Jiao, Yuyao; Yin, Wenli; Zhang, Lili

Year: 2024

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2024.0318

Paper Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy.

Xu, Tianjie; Liu, Kainan; Fan, Jiaxin et al. · 2024 · Open life sciences · DOI

Full title: Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy.

Authors: Xu, Tianjie; Liu, Kainan; Fan, Jiaxin; Jia, Xiang; Guo, Xiaoling; Zhao, Xingwang; Cao, Yanhua; Zhang, Hui; Wang, Qian

Year: 2024

Venue: Open life sciences

DOI: https://doi.org/10.1515/biol-2022-0922

Paper Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment

Cordani, Marco; Somoza, Álvaro · 2018 · Cellular and Molecular Life Sciences · DOI

Full title: Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment

Authors: Cordani, Marco; Somoza, Álvaro

Year: 2018

Venue: Cellular and Molecular Life Sciences

DOI: https://doi.org/10.1007/s00018-018-2973-y

Paper Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes

Zuroff, Leah; Daley, David A.; Black, Keith L. et al. · 2017 · Cellular and Molecular Life Sciences · DOI

Full title: Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes

Authors: Zuroff, Leah; Daley, David A.; Black, Keith L.; Koronyo‐Hamaoui, Maya

Year: 2017

Venue: Cellular and Molecular Life Sciences

DOI: https://doi.org/10.1007/s00018-017-2463-7

Paper PROTACs: great opportunities for academia and industry

Sun, Xiuyun; Gao, Hongying; Yang, Yiqing et al. · 2019 · Signal Transduction and Targeted Therapy · DOI

Full title: PROTACs: great opportunities for academia and industry

Authors: Sun, Xiuyun; Gao, Hongying; Yang, Yiqing; He, Ming; Wu, Yue; Song, Yu-Gang; Tong, Yan; Rao, Yu

Year: 2019

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-019-0101-6

Paper History and progress of hypotheses and clinical trials for Alzheimer’s disease

Liu, Peipei; Xie, Yi; Meng, Xiao‐Yan et al. · 2019 · Signal Transduction and Targeted Therapy · DOI

Full title: History and progress of hypotheses and clinical trials for Alzheimer’s disease

Authors: Liu, Peipei; Xie, Yi; Meng, Xiao‐Yan; Kang, Jian‐Sheng

Year: 2019

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-019-0063-8

Paper NAD+ metabolism, stemness, the immune response, and cancer

Navas, Lola E.; Carnero, Amancio · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: NAD+ metabolism, stemness, the immune response, and cancer

Authors: Navas, Lola E.; Carnero, Amancio

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-020-00354-w

Paper Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

Li, Chen; Ni, Yu‐Qing; Xu, Hui et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

Authors: Li, Chen; Ni, Yu‐Qing; Xu, Hui; Xiang, Qunyan; Zhao, Yan; Zhan, Junkun; He, Jieyu; Li, Shuang; Liu, You‐Shuo

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00779-x

Paper Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Guo, Jun; Huang, Xiuqing; Dou, Lin et al. · 2022 · Signal Transduction and Targeted Therapy · DOI

Full title: Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Authors: Guo, Jun; Huang, Xiuqing; Dou, Lin; Yan, Mingjing; Shen, Tao; Tang, Weiqing; Li, Jian

Year: 2022

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-022-01251-0

Paper Dietary regulation in health and disease

Wu, Qi; Gao, Zhijie; Yu, Xin et al. · 2022 · Signal Transduction and Targeted Therapy · DOI

Full title: Dietary regulation in health and disease

Authors: Wu, Qi; Gao, Zhijie; Yu, Xin; Wang, Ping

Year: 2022

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-022-01104-w

Paper Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

Gao, Chao; Jiang, Jingwen; Tan, Yuyan et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

Authors: Gao, Chao; Jiang, Jingwen; Tan, Yuyan; Chen, Shengdi

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01588-0

Paper Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

Chen, Xingyi; Shi, Chaoran; He, Meihui et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

Authors: Chen, Xingyi; Shi, Chaoran; He, Meihui; Xiong, Siqi; Xia, Xiaobo

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01570-w

Paper Metabolic landscape in cardiac aging: insights into molecular biology and therapeutic implications

Xie, Saiyang; Xu, Si‐Chi; Deng, Wei et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Metabolic landscape in cardiac aging: insights into molecular biology and therapeutic implications

Authors: Xie, Saiyang; Xu, Si‐Chi; Deng, Wei; Tang, Qizhu

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01378-8

Paper Mitochondrial dynamics in health and disease: mechanisms and potential targets

Chen, Wen; Zhao, Huakan; Li, Yongsheng · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Mitochondrial dynamics in health and disease: mechanisms and potential targets

Authors: Chen, Wen; Zhao, Huakan; Li, Yongsheng

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01547-9

Paper Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease

Panwar, Vivek; Singh, Aishwarya; Bhatt, Manini et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease

Authors: Panwar, Vivek; Singh, Aishwarya; Bhatt, Manini; Tonk, Rajiv Kumar; Azizov, Shavkatjon; Raza, Agha Saquib; Sengupta, Shinjinee; Kumar, Deepak; Garg, Manoj

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01608-z

Paper Targeting ferroptosis opens new avenues for the development of novel therapeutics

Sun, Shumin; Shen, Jie; Jiang, Jianwei et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Targeting ferroptosis opens new avenues for the development of novel therapeutics

Authors: Sun, Shumin; Shen, Jie; Jiang, Jianwei; Wang, Fudi; Min, Junxia

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01606-1

Paper Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases

Lu, Qian; Zhu, Yanli; Deng, Chao et al. · 2024 · Signal Transduction and Targeted Therapy · DOI

Full title: Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases

Authors: Lu, Qian; Zhu, Yanli; Deng, Chao; Liang, Zhenxing; Chen, Junmin; Chen, Ying; Wang, Xue; Liu, Yanqing; Tian, Ye; Yang, Yang

Year: 2024

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-024-01756-w

Paper Multifunctional nanoparticle-mediated combining therapy for human diseases

Li, Xiaotong; Peng, Xiuju; Zoulikha, Makhloufi et al. · 2024 · Signal Transduction and Targeted Therapy · DOI

Full title: Multifunctional nanoparticle-mediated combining therapy for human diseases

Authors: Li, Xiaotong; Peng, Xiuju; Zoulikha, Makhloufi; Boafo, George Frimpong; Magar, Kosheli Thapa; Ju, Yanmin; He, Wei

Year: 2024

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01668-1

Paper Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A. et al. · 2018 · Cell Death and Differentiation · DOI

Full title: Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Authors: Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A.; Abrams, John; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Annicchiarico‐Petruzzelli, Margherita; Antonov, Alexey V.; Arama, Eli; Baehrecke, Eric H.; Barlev, Nickolai A.; Bazán, Nicolás G.; Bernassola, Francesca; Bertrand, Mathieu J.M.; Bianchi, Katiuscia; Blagosklonny, Mikhail V.; Blomgren, Klas; Borner, Christoph; Boya, Patricia; Brenner, Catherine; Campanella, Michelangelo; Candi, Eleonora; Carmona‐Gutiérrez, Didac; Cecconi, Francesco; Chan, Francis Ka-Ming; Chandel, Navdeep S.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Cohen, Gerald M.; Conrad, Marcus; Cubillos‐Ruiz, Juan R.; Czabotar, Peter E.; D’Angiolella, Vincenzo; Dawson, Ted M.; Dawson, Valina L.; Laurenzi, Vincenzo De; Maria, Ruggero De; Debatin, Klaus‐Michael; DeBerardinis, Ralph J.; Deshmukh, Mohanish; Domenico, Fabio Di; Virgilio, Francesco Di; Dixit, Vishva M.; Dixon, Scott J.; Duckett, Colin S.; Dynlacht, Brian David; El‐Deiry, Wafik S.; Elrod, John W.; Fimia, Gian María; Fulda, Simone; García‐Sáez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Golstein, Pierre; Gottlieb, Eyal; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Gross, Atan; Hajnóczky, György; Hardwick, J. Marie; Harris, Isaac S.; Hengartner, Michael O.; Hetz, Claudio; Ichijo, Hidenori; Jäättelä, Marja; Joseph, Bertrand; Jost, Philipp J.; Juin, Philippe; Kaiser, William J.; Karin, Michael; Kaufmann, Thomas; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Knight, Richard A.; Kumar, Sharad; Lee, Sam W.; Lemasters, John J.; Levine, Beth; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; López-Otı́n, Carlos; Lowe, Scott W.; Luedde, Tom; Lugli, Enrico; MacFarlane, Marion; Madeo, Frank; Malewicz, Michal; Malorni, Walter; Manic, Gwenola

Year: 2018

Venue: Cell Death and Differentiation

DOI: https://doi.org/10.1038/s41418-017-0012-4

Paper Inflammasome activation and regulation: toward a better understanding of complex mechanisms

Zheng, Danping; Liwinski, Timur; Elinav, Eran · 2020 · Cell Discovery · DOI

Full title: Inflammasome activation and regulation: toward a better understanding of complex mechanisms

Authors: Zheng, Danping; Liwinski, Timur; Elinav, Eran

Year: 2020

Venue: Cell Discovery

DOI: https://doi.org/10.1038/s41421-020-0167-x

Paper Phytochemical-mediated efferocytosis and autophagy in inflammation control.

Vafadar, Asma; Tajbakhsh, Amir; Hosseinpour-Soleimani, Fatemeh et al. · 2024 · Cell death discovery · DOI

Full title: Phytochemical-mediated efferocytosis and autophagy in inflammation control.

Authors: Vafadar, Asma; Tajbakhsh, Amir; Hosseinpour-Soleimani, Fatemeh; Savardshtaki, Amir; Hashempur, Mohammad Hashem

Year: 2024

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-024-02254-2

Paper Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

Xie, Chenglong; Zhuang, Xu‐Xu; Niu, Zhangming et al. · 2022 · Nature Biomedical Engineering · DOI

Full title: Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

Authors: Xie, Chenglong; Zhuang, Xu‐Xu; Niu, Zhangming; Ai, Ruixue; Lautrup, Sofie; Zheng, Shuangjia; Jiang, Yinghui; Han, Ruiyu; Gupta, Tanima Sen; Cao, Shuqin; Lagartos-Donate, Mariá José; Cai, Cui-Zan; Xie, Liming; Caponio, Domenica; Wang, Wenwen; Schmauck‐Medina, Tomas; Zhang, Jianying; Wang, Heling; Lou, Guofeng; Xiao, Xianglu; Zheng, Wenhua; Palikaras, Konstantinos; Yang, Guang; Caldwell, Kim A.; Caldwell, Guy A.; Shen, Han‐Ming; Nilsen, Hilde; Lu, Jiahong; Fang, Evandro Fei

Year: 2022

Venue: Nature Biomedical Engineering

DOI: https://doi.org/10.1038/s41551-021-00819-5

Paper Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases-Progress and Prognosis

Lindquist, S. L.; Kelly, Jeffery W. · 2011 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases-Progress and Prognosis

Authors: Lindquist, S. L.; Kelly, Jeffery W.

Year: 2011

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a004507

Paper Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration.

Wu, Yan; Li, Luxin; Ning, Zuojun et al. · 2024 · Cell communication and signaling : CCS · DOI

Full title: Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration.

Authors: Wu, Yan; Li, Luxin; Ning, Zuojun; Li, Changrong; Yin, Yongkui; Chen, Kaiyuan; Li, Lu; Xu, Fei; Gao, Jie

Year: 2024

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-023-01346-3

Paper Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation

Chen, Yijun; Yu, Yang · 2023 · Journal of Neuroinflammation · DOI

Full title: Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation

Authors: Chen, Yijun; Yu, Yang

Year: 2023

Venue: Journal of Neuroinflammation

DOI: https://doi.org/10.1186/s12974-023-02853-3

Paper Potential of phytochemicals in the treatment of Alzheimer disease by modulating lysosomal dysfunction: a systematic review.

Yuan, Man; Nguyen, Trinh Thach Thi; Gibb, Alasdair J et al. · 2025 · Chinese medicine · DOI

Full title: Potential of phytochemicals in the treatment of Alzheimer disease by modulating lysosomal dysfunction: a systematic review.

Authors: Yuan, Man; Nguyen, Trinh Thach Thi; Gibb, Alasdair J; Xian, Yan-Fang; Xu, Hong-Xi

Year: 2025

Venue: Chinese medicine

DOI: https://doi.org/10.1186/s13020-025-01204-z

Paper APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases

Fernández‐Calle, Rosalía; Konings, Sabine C; Frontiñán-Rubio, Javier et al. · 2022 · Molecular Neurodegeneration · DOI

Full title: APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases

Authors: Fernández‐Calle, Rosalía; Konings, Sabine C; Frontiñán-Rubio, Javier; García‐Revilla, Juan; Camprubí-Ferrer, Lluís; Svensson, Martina; Martinson, Isak; Boza‐Serrano, Antonio; Venero, José L.; Nielsen, Henrietta M.; Gouras, Gunnar K.; Deierborg, Tomas

Year: 2022

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/s13024-022-00566-4

Paper Molecular and cellular pathways contributing to brain aging

Zia, Aliabbas; Pourbagher‐Shahri, Ali Mohammad; Farkhondeh, Tahereh et al. · 2021 · Behavioral and Brain Functions · DOI

Full title: Molecular and cellular pathways contributing to brain aging

Authors: Zia, Aliabbas; Pourbagher‐Shahri, Ali Mohammad; Farkhondeh, Tahereh; Samarghandian, Saeed

Year: 2021

Venue: Behavioral and Brain Functions

DOI: https://doi.org/10.1186/s12993-021-00179-9

Paper Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

Querfurth, Henry; Lee, Hankyu · 2021 · Molecular Neurodegeneration · DOI

Full title: Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

Authors: Querfurth, Henry; Lee, Hankyu

Year: 2021

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/s13024-021-00428-5

Paper Tauopathies: new perspectives and challenges

Zhang, Yi; Wu, Kaimin; Liu, Yang et al. · 2022 · Molecular Neurodegeneration · DOI

Full title: Tauopathies: new perspectives and challenges

Authors: Zhang, Yi; Wu, Kaimin; Liu, Yang; Dong, Qiang; Yu, Jin‐Tai

Year: 2022

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/s13024-022-00533-z

Paper Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease.

Morrone, Christopher Daniel; Raghuraman, Radha; Hussaini, S Abid et al. · 2023 · Molecular neurodegeneration · DOI

Full title: Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease.

Authors: Morrone, Christopher Daniel; Raghuraman, Radha; Hussaini, S Abid; Yu, Wai Haung

Year: 2023

Venue: Molecular neurodegeneration

DOI: https://doi.org/10.1186/s13024-023-00617-4

Paper Autophagic and endo-lysosomal dysfunction in neurodegenerative disease

Malik, Bilal R.; Maddison, Daniel C.; Smith, Gaynor A. et al. · 2019 · Molecular Brain · DOI

Full title: Autophagic and endo-lysosomal dysfunction in neurodegenerative disease

Authors: Malik, Bilal R.; Maddison, Daniel C.; Smith, Gaynor A.; Peters, Owen M.

Year: 2019

Venue: Molecular Brain

DOI: https://doi.org/10.1186/s13041-019-0504-x

Paper Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Maiti, Panchanan; Manna, Jayeeta; Dunbar, Gary · 2017 · Translational Neurodegeneration · DOI

Full title: Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Authors: Maiti, Panchanan; Manna, Jayeeta; Dunbar, Gary

Year: 2017

Venue: Translational Neurodegeneration

DOI: https://doi.org/10.1186/s40035-017-0099-z

Paper Integration of cellular bioenergetics with mitochondrial quality control and autophagy

Hill, Bradford G.; Benavides, Gloria A.; Lancaster, Jack R. et al. · 2012 · Biological Chemistry · DOI

Full title: Integration of cellular bioenergetics with mitochondrial quality control and autophagy

Authors: Hill, Bradford G.; Benavides, Gloria A.; Lancaster, Jack R.; Ballinger, Scott W.; Dell’Italia, Lou; Zhang, Jianhua; Darley‐Usmar, Victor

Year: 2012

Venue: Biological Chemistry

DOI: https://doi.org/10.1515/hsz-2012-0198

Paper Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.

McCubrey, James A.; Steelman, Linda S.; Chappell, William H. et al. · 2012 · Oncotarget · DOI

Full title: Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.

Authors: McCubrey, James A.; Steelman, Linda S.; Chappell, William H.; Abrams, Stephen L.; Montalto, Giuseppe; Cervello, Melchiorre; Nicoletti, Ferdinando; Fagone, Paolo; Malaponte, Grazia; Mazzarino, María Clorinda; Candido, Saverio; Libra, Massimo; Bäsecke, Jörg; Mijatović, Sanja; Maksimović‐Ivanić, Danijela; Milella, Michèle; Tafuri, Agostino; Cocco, Lucio; Evangelisti, Camilla; Chiarini, Francesca; Martelli, Alberto M.

Year: 2012

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.652

Paper Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.

Zhou, Zhi-Wei; Li, Xing-Xiao; He, Zhi-Xu et al. · 2015 · Drug design, development and therapy · DOI

Full title: Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.

Authors: Zhou, Zhi-Wei; Li, Xing-Xiao; He, Zhi-Xu; Pan, Shu-Ting; Yang, Yinxue; Zhang, Xueji; Chow, Kevin; Yang, Tianxin; Qiu, Jia-Xuan; Zhou, Qingyu; Tan, Jun; Wang, Dong; Zhou, Shu-Feng

Year: 2015

Venue: Drug design, development and therapy

DOI: https://doi.org/10.2147/DDDT.S75976

Paper A Comprehensive Review on Factors Influences Biogenesis, Functions, Therapeutic and Clinical Implications of Exosomes

Gurunathan, Sangiliyandi; Kang, Min-Hee; Kim, Jin‐Hoi · 2021 · International Journal of Nanomedicine · DOI

Full title: A Comprehensive Review on Factors Influences Biogenesis, Functions, Therapeutic and Clinical Implications of Exosomes

Authors: Gurunathan, Sangiliyandi; Kang, Min-Hee; Kim, Jin‐Hoi

Year: 2021

Venue: International Journal of Nanomedicine

DOI: https://doi.org/10.2147/ijn.s291956

Paper Metabolic Reprogramming in Glioma

Strickland, Marie; Stoll, Elizabeth A. · 2017 · Frontiers in Cell and Developmental Biology · DOI

Full title: Metabolic Reprogramming in Glioma

Authors: Strickland, Marie; Stoll, Elizabeth A.

Year: 2017

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2017.00043

Paper Metabolism of Amino Acids in Cancer

Wei, Zhen; Liu, Xiaoyi; Cheng, Chunming et al. · 2021 · Frontiers in Cell and Developmental Biology · DOI

Full title: Metabolism of Amino Acids in Cancer

Authors: Wei, Zhen; Liu, Xiaoyi; Cheng, Chunming; Yu, Wei; Yi, Ping

Year: 2021

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.603837

Paper The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration

Azam, Shofiul; Haque, Md. Ezazul; Balakrishnan, Rengasamy et al. · 2021 · Frontiers in Cell and Developmental Biology · DOI

Full title: The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration

Authors: Azam, Shofiul; Haque, Md. Ezazul; Balakrishnan, Rengasamy; Kim, In‐Su; Choi, Dong‐Kug

Year: 2021

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2021.683459

Paper Protein misfolding and mitochondrial dysfunction in glaucoma.

Venkatesan, Arunkumar; Bernstein, Audrey M · 2025 · Frontiers in cell and developmental biology · DOI

Full title: Protein misfolding and mitochondrial dysfunction in glaucoma.

Authors: Venkatesan, Arunkumar; Bernstein, Audrey M

Year: 2025

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2025.1595121

Paper Microglia and programmed cell death in spinal cord injury: beyond apoptosis.

Huang, Ming; Yao, Guoquan; He, Baowen et al. · 2025 · Frontiers in cell and developmental biology · DOI

Full title: Microglia and programmed cell death in spinal cord injury: beyond apoptosis.

Authors: Huang, Ming; Yao, Guoquan; He, Baowen; Zhou, Xiaohu; Liu, Guoqing; Dong, Wenfei

Year: 2025

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2025.1656732

Paper Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function

Rowlands, Jordan; Heng, Julian Ik‐Tsen; Newsholme, Philip et al. · 2018 · Frontiers in Endocrinology · DOI

Full title: Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function

Authors: Rowlands, Jordan; Heng, Julian Ik‐Tsen; Newsholme, Philip; Carlessi, Rodrigo

Year: 2018

Venue: Frontiers in Endocrinology

DOI: https://doi.org/10.3389/fendo.2018.00672

Paper Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines

Rea, Irene Maeve; Gibson, David S.; McGilligan, Victoria et al. · 2018 · Frontiers in Immunology · DOI

Full title: Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines

Authors: Rea, Irene Maeve; Gibson, David S.; McGilligan, Victoria; McNerlan, Susan; Alexander, H. Denis; Ross, Owen A.

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.00586

Paper Microglial cell dysregulation in brain aging and neurodegeneration

Bernhardi, Rommy von; Bernhardi, Laura Eugenín-von; Eugenı́n, Jaime · 2015 · Frontiers in Aging Neuroscience · DOI

Full title: Microglial cell dysregulation in brain aging and neurodegeneration

Authors: Bernhardi, Rommy von; Bernhardi, Laura Eugenín-von; Eugenı́n, Jaime

Year: 2015

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2015.00124

Paper Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials

Miao, Jifei; Ma, Haixia; Yang, Yang et al. · 2023 · Frontiers in Aging Neuroscience · DOI

Full title: Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials

Authors: Miao, Jifei; Ma, Haixia; Yang, Yang; Liao, Yuanpin; Cui, Lin; Zheng, Juanxia; Yu, Muli; Lan, Jiao

Year: 2023

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2023.1201982

Paper Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

Brites, Dora; Fernandes, Adelaide · 2015 · Frontiers in Cellular Neuroscience · DOI

Full title: Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

Authors: Brites, Dora; Fernandes, Adelaide

Year: 2015

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2015.00476

Paper The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases

Blevins, Hallie; Xu, Yiming; Biby, Savannah et al. · 2022 · Frontiers in Aging Neuroscience · DOI

Full title: The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases

Authors: Blevins, Hallie; Xu, Yiming; Biby, Savannah; Zhang, Shijun

Year: 2022

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2022.879021

Paper Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets

Ng, Si Yun; Lee, Alan Yiu Wah · 2019 · Frontiers in Cellular Neuroscience · DOI

Full title: Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets

Authors: Ng, Si Yun; Lee, Alan Yiu Wah

Year: 2019

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2019.00528

Paper - **Authors:** Chatterjee, Shreyasi, Mudher, Amritpal - **Year:** 2018 - **Journal:** Frontiers in Neuroscience - **Source:** openalex

Chatterjee, Shreyasi; Mudher, Amritpal · 2018 · Frontiers in Neuroscience · DOI

Full title: - **Authors:** Chatterjee, Shreyasi, Mudher, Amritpal - **Year:** 2018 - **Journal:** Frontiers in Neuroscience - **Source:** openalex

Authors: Chatterjee, Shreyasi; Mudher, Amritpal

Year: 2018

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2018.00383

Paper ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

Mejzini, Rita; Flynn, Loren L.; Pitout, Ianthe et al. · 2019 · Frontiers in Neuroscience · DOI

Full title: ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

Authors: Mejzini, Rita; Flynn, Loren L.; Pitout, Ianthe; Fletcher, Sue; Wilton, Steve D.; Akkari, P. Anthony

Year: 2019

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2019.01310

Paper Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

Prasad, A. Aditya; Bharathi, Vidhya; Sivalingam, Vishwanath et al. · 2019 · Frontiers in Molecular Neuroscience · DOI

Full title: Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

Authors: Prasad, A. Aditya; Bharathi, Vidhya; Sivalingam, Vishwanath; Girdhar, Amandeep; Patel, Basant K.

Year: 2019

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2019.00025

Paper Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update

Cenini, Giovanna; Voos, Wolfgang · 2019 · Frontiers in Pharmacology · DOI

Full title: Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update

Authors: Cenini, Giovanna; Voos, Wolfgang

Year: 2019

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2019.00902

Paper The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

Savio, Luiz Eduardo Baggio; Mello, Paola de Andrade; Silva, Cleide Gonçalves da et al. · 2018 · Frontiers in Pharmacology · DOI

Full title: The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

Authors: Savio, Luiz Eduardo Baggio; Mello, Paola de Andrade; Silva, Cleide Gonçalves da; Coutinho‐Silva, Robson

Year: 2018

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2018.00052

Paper Nanocurcumin: A Promising Candidate for Therapeutic Applications

Karthikeyan, Adhimoolam; Senthil, N.; Min, Taesun · 2020 · Frontiers in Pharmacology · DOI

Full title: Nanocurcumin: A Promising Candidate for Therapeutic Applications

Authors: Karthikeyan, Adhimoolam; Senthil, N.; Min, Taesun

Year: 2020

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00487

Paper Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Webster, Jack M.; Darling, April L.; Uversky, Vladimir N. et al. · 2019 · Frontiers in Pharmacology · DOI

Full title: Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Authors: Webster, Jack M.; Darling, April L.; Uversky, Vladimir N.; Blair, Laura J.

Year: 2019

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2019.01047

Paper The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets

Liang, Tao; Zhang, Yang; Wu, Suyuan et al. · 2022 · Frontiers in Pharmacology · DOI

Full title: The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets

Authors: Liang, Tao; Zhang, Yang; Wu, Suyuan; Chen, Qingjie; Wang, Lin

Year: 2022

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2022.845185

Paper Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases

Sharifi‐Rad, Mehdi; Kumar, N. V. Anil; Zucca, Paolo et al. · 2020 · Frontiers in Physiology · DOI

Full title: Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases

Authors: Sharifi‐Rad, Mehdi; Kumar, N. V. Anil; Zucca, Paolo; Varoni, Elena Maria; Dini, Luciana; Panzarini, Elisa; Rajković, Jovana; Fokou, Patrick Valère Tsouh; Azzini, Elena; Peluso, Ilaria; Mishra, Abhay Prakash; Nigam, Manisha; Rayess, Youssef El; Beyrouthy, Marc El; Polito, Letizia; Iriti, Marcello; Martins, Natália; Martorell, Miquel; Docea, Anca Oana; Setzer, William N.; Călina, Daniela; Cho, William C.; Sharifi‐Rad, Javad

Year: 2020

Venue: Frontiers in Physiology

DOI: https://doi.org/10.3389/fphys.2020.00694

Paper Neuroinflammation in Alzheimer’s Disease

Onyango, Isaac G.; Jáuregui, Gretsen Velezmoro; Čarná, Mária et al. · 2021 · Biomedicines · DOI

Full title: Neuroinflammation in Alzheimer’s Disease

Authors: Onyango, Isaac G.; Jáuregui, Gretsen Velezmoro; Čarná, Mária; Bennett, James P.; Stokin, Gorazd B.

Year: 2021

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines9050524

Paper The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy.

Atia, Amany Aa; Ashour, Rehab H; Zaki, Marwa Maf et al. · 2023 · Psychopharmacology · DOI

Full title: The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy.

Authors: Atia, Amany Aa; Ashour, Rehab H; Zaki, Marwa Maf; Rahman, Karawan Ma; Ramadan, Nehal M

Year: 2023

Venue: Psychopharmacology

DOI: https://doi.org/10.1007/s00213-023-06371-1

Paper Cardiac proteostasis in obesity and cardiovascular disease.

Guerra, Joel; Matta, Leonardo; Bartelt, Alexander · 2024 · Herz · DOI

Full title: Cardiac proteostasis in obesity and cardiovascular disease.

Authors: Guerra, Joel; Matta, Leonardo; Bartelt, Alexander

Year: 2024

Venue: Herz

DOI: https://doi.org/10.1007/s00059-024-05233-6

Paper Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy.

Gatica, Damián; Klionsky, Daniel J · 2019 · Current genetics · DOI

Full title: Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy.

Authors: Gatica, Damián; Klionsky, Daniel J

Year: 2019

Venue: Current genetics

DOI: https://doi.org/10.1007/s00294-019-00943-5

Paper FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Marrone, Lara; Drexler, Hannes C. A.; Wang, Jie et al. · 2019 · Acta Neuropathologica · DOI

Full title: FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Authors: Marrone, Lara; Drexler, Hannes C. A.; Wang, Jie; Tripathi, Priyanka; Distler, Tania; Heisterkamp, Patrick; Anderson, Eric N.; Kour, Sukhleen; Moraiti, Anastasia; Maharana, Shovamayee; Bhatnagar, Rajat; Belgard, T. Grant; Tripathy, Vadreenath; Kalmbach, Norman; Hosseinzadeh, Zohreh; Crippa, V.; Abo-Rady, Masin; Wegner, Florian; Poletti, Angelo; Troost, Dirk; Aronica, Eleonora; Busskamp, Volker; Weis, Joachim; Pandey, Udai Bhan; Hyman, Anthony A.; Alberti, Simon; Goswami, Anand; Sterneckert, Jared

Year: 2019

Venue: Acta Neuropathologica

DOI: https://doi.org/10.1007/s00401-019-01998-x

Paper Glaucoma: the retina and beyond

Davis, Benjamin; Crawley, Laura; Pahlitzsch, Milena et al. · 2016 · Acta Neuropathologica · DOI

Full title: Glaucoma: the retina and beyond

Authors: Davis, Benjamin; Crawley, Laura; Pahlitzsch, Milena; Javaid, Fatimah Zara; Cordeiro, M. Francesca

Year: 2016

Venue: Acta Neuropathologica

DOI: https://doi.org/10.1007/s00401-016-1609-2

Paper Cardioprotection requires taking out the trash.

Gottlieb, Roberta A; Finley, Kim D; Mentzer, Robert M · 2009 · Basic research in cardiology · DOI

Full title: Cardioprotection requires taking out the trash.

Authors: Gottlieb, Roberta A; Finley, Kim D; Mentzer, Robert M

Year: 2009

Venue: Basic research in cardiology

DOI: https://doi.org/10.1007/s00395-009-0011-9

Paper Spinocerebellar ataxia: an update

Sullivan, Roisin; Yau, Wai Yan; O’Connor, Emer et al. · 2018 · Journal of Neurology · DOI

Full title: Spinocerebellar ataxia: an update

Authors: Sullivan, Roisin; Yau, Wai Yan; O’Connor, Emer; Houlden, Henry

Year: 2018

Venue: Journal of Neurology

DOI: https://doi.org/10.1007/s00415-018-9076-4

Paper Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Sánchez‐Varo, Raquel; Trujillo‐Estrada, Laura; Sánchez‐Mejías, Elisabeth et al. · 2011 · Acta Neuropathologica · DOI

Full title: Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Authors: Sánchez‐Varo, Raquel; Trujillo‐Estrada, Laura; Sánchez‐Mejías, Elisabeth; Torres, M.; Baglietto‐Vargas, David; Moreno‐González, Inés; Castro, Vanessa De; Jiménez, Sebastián; Ruano, Diego; Vizuete, Marisa; Dávila, José Carlos; García‐Verdugo, José Manuel; Jiménez, Antonio J.; Vitórica, Javier; Gutiérrez, Antonia

Year: 2011

Venue: Acta Neuropathologica

DOI: https://doi.org/10.1007/s00401-011-0896-x

Paper ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome-PTEN-mTOR-autophagy pathway.

Han, Xiao; Zhang, Yun-Long; Lin, Qiu-Yue et al. · 2023 · Cell biology and toxicology · DOI

Full title: ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome-PTEN-mTOR-autophagy pathway.

Authors: Han, Xiao; Zhang, Yun-Long; Lin, Qiu-Yue; Li, Hui-Hua; Guo, Shu-Bin

Year: 2023

Venue: Cell biology and toxicology

DOI: https://doi.org/10.1007/s10565-022-09699-0

Paper Two New Considerations for Improving the Diagnosis of α1-Antitrypsin Deficiency-Associated Liver Disease

D. Perlmutter; K. Chopra; Andrew S Chu · 2015 · Digestive Diseases and Sciences · DOI

Full title: Two New Considerations for Improving the Diagnosis of α1-Antitrypsin Deficiency-Associated Liver Disease

Authors: D. Perlmutter; K. Chopra; Andrew S Chu

Year: 2015

Venue: Digestive Diseases and Sciences

DOI: https://doi.org/10.1007/s10620-015-3553-8

Paper Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration

Kaarniranta, Kai; Tokarz, Paulina; Koskela, Ali et al. · 2016 · Cell Biology and Toxicology · DOI

Full title: Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration

Authors: Kaarniranta, Kai; Tokarz, Paulina; Koskela, Ali; Paterno, Jussi J.; Błasiak, Janusz

Year: 2016

Venue: Cell Biology and Toxicology

DOI: https://doi.org/10.1007/s10565-016-9371-8

Paper The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.

El-Maraghy, Shohda A; Reda, Aya; Essam, Reham M et al. · 2023 · Inflammopharmacology · DOI

Full title: The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.

Authors: El-Maraghy, Shohda A; Reda, Aya; Essam, Reham M; Kortam, Mona A

Year: 2023

Venue: Inflammopharmacology

DOI: https://doi.org/10.1007/s10787-023-01292-z

Paper Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.

Chen, Chang; Xia, Baomei; Tang, Lili et al. · 2019 · Metabolic brain disease · DOI

Full title: Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.

Authors: Chen, Chang; Xia, Baomei; Tang, Lili; Wu, Wei; Tang, Juanjuan; Liang, Yan; Yang, Hui; Zhang, Zhennian; Lu, Yan; Chen, Gang; Yang, Ye; Zhao, Yang

Year: 2019

Venue: Metabolic brain disease

DOI: https://doi.org/10.1007/s11011-018-0330-3

Paper Functional and transcriptional profiling of microglial activation during the chronic phase of TBI identifies an age-related driver of poor outcome in old mice.

Ritzel, Rodney M; Li, Yun; Lei, Zhuofan et al. · 2022 · GeroScience · DOI

Full title: Functional and transcriptional profiling of microglial activation during the chronic phase of TBI identifies an age-related driver of poor outcome in old mice.

Authors: Ritzel, Rodney M; Li, Yun; Lei, Zhuofan; Carter, Jordan; He, Junyun; Choi, Harry M C; Khan, Niaz; Li, Hui; Allen, Samantha; Lipinski, Marta M; Faden, Alan I; Wu, Junfang

Year: 2022

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00562-y

Paper Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial

Chung, Christina Lee; Lawrence, Ibiyonu; Hoffman, Melissa et al. · 2019 · GeroScience · DOI

Full title: Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial

Authors: Chung, Christina Lee; Lawrence, Ibiyonu; Hoffman, Melissa; Elgindi, Dareen; Nadhan, Kumar S.; Potnis, Manali; Jin, Annie; Sershon, Catlin; Binnebose, Rhonda; Lorenzini, Antonello; Sell, Christian

Year: 2019

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-019-00113-y

Paper Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model.

Yu, Xin; Ajayi, Abiodun; Boga, Narasimha Rao et al. · 2012 · Journal of molecular neuroscience : MN · DOI

Full title: Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model.

Authors: Yu, Xin; Ajayi, Abiodun; Boga, Narasimha Rao; Ström, Anna-Lena

Year: 2012

Venue: Journal of molecular neuroscience : MN

DOI: https://doi.org/10.1007/s12031-012-9722-8

Paper Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury

Anzell, Anthony R.; Maizy, Rita; Przyklenk, Karin et al. · 2017 · Molecular Neurobiology · DOI

Full title: Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury

Authors: Anzell, Anthony R.; Maizy, Rita; Przyklenk, Karin; Sanderson, Thomas H.

Year: 2017

Venue: Molecular Neurobiology

DOI: https://doi.org/10.1007/s12035-017-0503-9

Paper Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin C.

Fang, Zongping; Feng, Yun; Li, Yuheng et al. · 2019 · Neuroscience bulletin · DOI

Full title: Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin C.

Authors: Fang, Zongping; Feng, Yun; Li, Yuheng; Deng, Jiao; Nie, Huang; Yang, Qianzhi; Wang, Shiquan; Dong, Hailong; Xiong, Lize

Year: 2019

Venue: Neuroscience bulletin

DOI: https://doi.org/10.1007/s12264-018-0313-8

Paper Regulation of autophagy by Ca2.

Sun, Fang; Xu, Xia; Wang, Xiaohong et al. · 2016 · Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · DOI

Full title: Regulation of autophagy by Ca2.

Authors: Sun, Fang; Xu, Xia; Wang, Xiaohong; Zhang, Bei

Year: 2016

Venue: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

DOI: https://doi.org/10.1007/s13277-016-5353-y

Paper Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders.

Mitoma, H; Buffo, A; Gelfo, F et al. · 2020 · Cerebellum (London, England) · DOI

Full title: Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders.

Authors: Mitoma, H; Buffo, A; Gelfo, F; Guell, X; Fucà, E; Kakei, S; Lee, J; Manto, M; Petrosini, L; Shaikh, A G; Schmahmann, J D

Year: 2020

Venue: Cerebellum (London, England)

DOI: https://doi.org/10.1007/s12311-019-01091-9

Paper Neuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke

Mao, Rui; Zong, Ningning; Hu, Yujie et al. · 2022 · Neuroscience Bulletin · DOI

Full title: Neuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke

Authors: Mao, Rui; Zong, Ningning; Hu, Yujie; Chen, Ying; Xu, Yun

Year: 2022

Venue: Neuroscience Bulletin

DOI: https://doi.org/10.1007/s12264-022-00859-0

Paper Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex.

Cai, Zhiyou; Zhou, Yingjun; Liu, Zhou et al. · 2015 · Neuropsychiatric disease and treatment · DOI

Full title: Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex.

Authors: Cai, Zhiyou; Zhou, Yingjun; Liu, Zhou; Ke, Zunyu; Zhao, Bin

Year: 2015

Venue: Neuropsychiatric disease and treatment

DOI: https://doi.org/10.2147/NDT.S84755

Paper Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells.

Chueaphromsri, Phongsakorn; Kunhorm, Phongsakorn; Sotthibundhu, Areechun et al. · 2026 · In vivo (Athens, Greece) · DOI

Full title: Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells.

Authors: Chueaphromsri, Phongsakorn; Kunhorm, Phongsakorn; Sotthibundhu, Areechun; Chaicharoenaudomrung, Nipha; Noisa, Parinya

Year: 2026

Venue: In vivo (Athens, Greece)

DOI: https://doi.org/10.21873/invivo.14186

Paper Monitoring Autophagy in Human Aging: Key Cell Models and Insights.

Moreno, Tatiana M; Nieto-Torres, Jose L; Kumsta, Caroline · 2025 · Frontiers in bioscience (Landmark edition) · DOI

Full title: Monitoring Autophagy in Human Aging: Key Cell Models and Insights.

Authors: Moreno, Tatiana M; Nieto-Torres, Jose L; Kumsta, Caroline

Year: 2025

Venue: Frontiers in bioscience (Landmark edition)

DOI: https://doi.org/10.31083/FBL27091

Paper Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease.

Ortiz-Vega, Natalie; Lobato, Amanda G; Canic, Tijana et al. · 2024 · Life science alliance · DOI

Full title: Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease.

Authors: Ortiz-Vega, Natalie; Lobato, Amanda G; Canic, Tijana; Zhu, Yi; Lazopulo, Stanislav; Syed, Sheyum; Zhai, R Grace

Year: 2024

Venue: Life science alliance

DOI: https://doi.org/10.26508/lsa.202402681

Paper Lamotrigine Enhances Autophagy and Reduces Post-Traumatic Spinal Neural Injury in Mice.

Zhang, Mengting; Chen, Li; Gao, Heren et al. · 2025 · Journal of integrative neuroscience · DOI

Full title: Lamotrigine Enhances Autophagy and Reduces Post-Traumatic Spinal Neural Injury in Mice.

Authors: Zhang, Mengting; Chen, Li; Gao, Heren; Liu, Tao

Year: 2025

Venue: Journal of integrative neuroscience

DOI: https://doi.org/10.31083/JIN37357

Paper Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.

Lu, Jinjin; Li, Rui; Ni, Shilei et al. · 2022 · Frontiers in bioengineering and biotechnology · DOI

Full title: Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.

Authors: Lu, Jinjin; Li, Rui; Ni, Shilei; Xie, Yuandong; Liu, Xinchen; Zhang, Kai; Li, Yi

Year: 2022

Venue: Frontiers in bioengineering and biotechnology

DOI: https://doi.org/10.3389/fbioe.2022.1002291

Paper Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease

Lindholm, Dan; Korhonen, Laura; Eriksson, Ove et al. · 2017 · Frontiers in Cell and Developmental Biology · DOI

Full title: Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease

Authors: Lindholm, Dan; Korhonen, Laura; Eriksson, Ove; Kõks, Sulev

Year: 2017

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2017.00048

Paper Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Xueke, Zhou; Hong, Yimei; Zhang, Hao et al. · 2020 · Frontiers in Cell and Developmental Biology · DOI

Full title: Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges

Authors: Xueke, Zhou; Hong, Yimei; Zhang, Hao; Li, Xin

Year: 2020

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.00364

Paper Mitophagy, Mitochondrial Homeostasis, and Cell Fate

Ma, Kaili; Chen, Guo; Li, Wenhui et al. · 2020 · Frontiers in Cell and Developmental Biology · DOI

Full title: Mitophagy, Mitochondrial Homeostasis, and Cell Fate

Authors: Ma, Kaili; Chen, Guo; Li, Wenhui; Kepp, Oliver; Zhu, Yushan; Chen, Quan

Year: 2020

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.00467

Paper Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.

Zhang, Wei; Hou, Weiduo; Chen, Mo et al. · 2020 · Frontiers in cell and developmental biology · DOI

Full title: Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.

Authors: Zhang, Wei; Hou, Weiduo; Chen, Mo; Chen, Erman; Xue, Deting; Ye, Chenyi; Li, Weixu; Pan, Zhijun

Year: 2020

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2020.576104

Paper The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy

Wang, Yigang; Liu, Huihui; Cao, Yuting et al. · 2020 · Frontiers in Cell and Developmental Biology · DOI

Full title: The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy

Authors: Wang, Yigang; Liu, Huihui; Cao, Yuting; Zhang, Leilei; Huang, Fang; Yi, Cong

Year: 2020

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2020.00413

Paper Assessing Autophagy in Muscle Stem Cells.

Campanario, Silvia; Ramírez-Pardo, Ignacio; Hong, Xiaotong et al. · 2020 · Frontiers in cell and developmental biology · DOI

Full title: Assessing Autophagy in Muscle Stem Cells.

Authors: Campanario, Silvia; Ramírez-Pardo, Ignacio; Hong, Xiaotong; Isern, Joan; Muñoz-Cánoves, Pura

Year: 2020

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2020.620409

Paper Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke.

Zang, Jiankun; Wu, Yousheng; Su, Xuanlin et al. · 2020 · Frontiers in cell and developmental biology · DOI

Full title: Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke.

Authors: Zang, Jiankun; Wu, Yousheng; Su, Xuanlin; Zhang, Tianyuan; Tang, Xionglin; Ma, Dan; Li, Yufeng; Liu, Yanfang; Weng, Ze'an; Liu, Xuanzhuo; Tsang, Chi Kwan; Xu, Anding; Lu, Dan

Year: 2020

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2020.616590

Paper A heterozygous p.S143P mutation in LMNA associates with proteasome dysfunction and enhanced autophagy-mediated degradation of mutant lamins A and C.

West, Gun; Turunen, Minttu; Aalto, Anna et al. · 2022 · Frontiers in cell and developmental biology · DOI

Full title: A heterozygous p.S143P mutation in LMNA associates with proteasome dysfunction and enhanced autophagy-mediated degradation of mutant lamins A and C.

Authors: West, Gun; Turunen, Minttu; Aalto, Anna; Virtanen, Laura; Li, Song-Ping; Heliö, Tiina; Meinander, Annika; Taimen, Pekka

Year: 2022

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2022.932983

Paper CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autophagy Pathway.

Xin, Shanshan; Li, Shao-Ming; Gao, Ling et al. · 2021 · Frontiers in cell and developmental biology · DOI

Full title: CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autophagy Pathway.

Authors: Xin, Shanshan; Li, Shao-Ming; Gao, Ling; Zheng, Jing-Jing; Wu, Yan-Wei; Shao, Chang-Lun; Ren, Wen-Hao; Zhi, Keqian

Year: 2021

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2021.779287

Paper Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.

Zhu, Huangrong; Liu, Hai; Chen, Xizhong et al. · 2022 · Frontiers in cell and developmental biology · DOI

Full title: Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.

Authors: Zhu, Huangrong; Liu, Hai; Chen, Xizhong; Xu, Xin; Zhang, Shuqin; Xie, Denghui

Year: 2022

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2022.971736

Paper Cardiomyocytes Cellular Phenotypes After Myocardial Infarction.

Lodrini, Alessandra Maria; Goumans, Marie-José · 2021 · Frontiers in cardiovascular medicine · DOI

Full title: Cardiomyocytes Cellular Phenotypes After Myocardial Infarction.

Authors: Lodrini, Alessandra Maria; Goumans, Marie-José

Year: 2021

Venue: Frontiers in cardiovascular medicine

DOI: https://doi.org/10.3389/fcvm.2021.750510

Paper Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes.

Ke, Minxia; Wang, Hao; Yang, Kailun et al. · 2025 · Frontiers in cell and developmental biology · DOI

Full title: Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes.

Authors: Ke, Minxia; Wang, Hao; Yang, Kailun; Ji, Meng; Qi, Nianmin; Wu, Yuehong

Year: 2025

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2025.1616235

Paper Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart Failure.

Li, Xuan; Flynn, Elizabeth R; do Carmo, Jussara M et al. · 2022 · Frontiers in cardiovascular medicine · DOI

Full title: Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart Failure.

Authors: Li, Xuan; Flynn, Elizabeth R; do Carmo, Jussara M; Wang, Zhen; da Silva, Alexandre A; Mouton, Alan J; Omoto, Ana C M; Hall, Michael E; Hall, John E

Year: 2022

Venue: Frontiers in cardiovascular medicine

DOI: https://doi.org/10.3389/fcvm.2022.859253

Paper LRP6 Knockdown Ameliorates Insulin Resistance via Modulation of Autophagy by Regulating GSK3β Signaling in Human LO2 Hepatocytes.

Li, Lei; Xue, Jing; Wan, Jipeng et al. · 2019 · Frontiers in endocrinology · DOI

Full title: LRP6 Knockdown Ameliorates Insulin Resistance via Modulation of Autophagy by Regulating GSK3β Signaling in Human LO2 Hepatocytes.

Authors: Li, Lei; Xue, Jing; Wan, Jipeng; Zhou, Qian; Wang, Shan; Zhou, Yu; Zhao, Heyong; Wang, Xietong

Year: 2019

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2019.00073

Paper NOD-Like Receptors: Master Regulators of Inflammation and Cancer

Saxena, Mansi; Yeretssian, Garabet · 2014 · Frontiers in Immunology · DOI

Full title: NOD-Like Receptors: Master Regulators of Inflammation and Cancer

Authors: Saxena, Mansi; Yeretssian, Garabet

Year: 2014

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2014.00327

Paper Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.

Hombach-Klonisch, Sabine; Natarajan, Suchitra; Thanasupawat, Thatchawan et al. · 2014 · Frontiers in endocrinology · DOI

Full title: Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.

Authors: Hombach-Klonisch, Sabine; Natarajan, Suchitra; Thanasupawat, Thatchawan; Medapati, Manoj; Pathak, Alok; Ghavami, Saeid; Klonisch, Thomas

Year: 2014

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2014.00037

Paper Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth.

Ben-Shmuel, Sarit; Rashed, Rola; Rostoker, Ran et al. · 2017 · Frontiers in endocrinology · DOI

Full title: Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth.

Authors: Ben-Shmuel, Sarit; Rashed, Rola; Rostoker, Ran; Isakov, Elina; Shen-Orr, Zila; LeRoith, Derek

Year: 2017

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2017.00173

Paper Emerging Roles of Exosomes in Normal and Pathological Conditions: New Insights for Diagnosis and Therapeutic Applications

Toro, Julieta De; Herschlik, Leticia; Waldner, Claudia et al. · 2015 · Frontiers in Immunology · DOI

Full title: Emerging Roles of Exosomes in Normal and Pathological Conditions: New Insights for Diagnosis and Therapeutic Applications

Authors: Toro, Julieta De; Herschlik, Leticia; Waldner, Claudia; Mongini, Claudia

Year: 2015

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2015.00203

Paper The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

Hu, Hai; Tian, Mingxing; Ding, Chan et al. · 2019 · Frontiers in Immunology · DOI

Full title: The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

Authors: Hu, Hai; Tian, Mingxing; Ding, Chan; Yu, Shengqing

Year: 2019

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.03083

Paper Inflammatory Bowel Disease: Genetics, Epigenetics, and Pathogenesis

Loddo, Italia; Romano, Claudio · 2015 · Frontiers in Immunology · DOI

Full title: Inflammatory Bowel Disease: Genetics, Epigenetics, and Pathogenesis

Authors: Loddo, Italia; Romano, Claudio

Year: 2015

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2015.00551

Paper Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

Angajala, Anusha; Lim, Sangbin; Phillips, Joshua B. et al. · 2018 · Frontiers in Immunology · DOI

Full title: Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

Authors: Angajala, Anusha; Lim, Sangbin; Phillips, Joshua B.; Kim, Jin Hwan; Yates, Clayton; You, Zongbing; Tan, Ming

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.01605

Paper The Role of Mitophagy in Innate Immunity

Gkikas, Ilias; Palikaras, Konstantinos; Tavernarakis, Nektarios · 2018 · Frontiers in Immunology · DOI

Full title: The Role of Mitophagy in Innate Immunity

Authors: Gkikas, Ilias; Palikaras, Konstantinos; Tavernarakis, Nektarios

Year: 2018

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2018.01283

Paper Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.

Jia, Jia; Gong, Xiaoying; Zhao, Yang et al. · 2019 · Frontiers in immunology · DOI

Full title: Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.

Authors: Jia, Jia; Gong, Xiaoying; Zhao, Yang; Yang, Zhenyu; Ji, Kaiqiang; Luan, Ting; Zang, Bin; Li, Guofu

Year: 2019

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2019.01491

Paper Autophagy and Host Defense in Nontuberculous Mycobacterial Infection

Silwal, Prashanta; Kim, In Soo; Jo, Eun‐Kyeong · 2021 · Frontiers in Immunology · DOI

Full title: Autophagy and Host Defense in Nontuberculous Mycobacterial Infection

Authors: Silwal, Prashanta; Kim, In Soo; Jo, Eun‐Kyeong

Year: 2021

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2021.728742

Paper Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease

Li, Yunna; Xia, Yun; Yin, Sijia et al. · 2021 · Frontiers in Immunology · DOI

Full title: Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease

Authors: Li, Yunna; Xia, Yun; Yin, Sijia; Wan, Fang; Hu, Junjie; Kou, Liang; Sun, Yadi; Wu, Jiawei; Zhou, Qiulu; Huang, Jinsha; Xiong, Nian; Wang, Tao

Year: 2021

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2021.719807

Paper Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

Li, Q; Li, H; Roughton, Karolina et al. · 2010 · Cell Death and Disease · DOI

Full title: Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

Authors: Li, Q; Li, H; Roughton, Karolina; Wang, Xiaoyang; Kroemer, Guido; Blomgren, Klas; Zhu, Changlian

Year: 2010

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2010.33

Paper Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis.

Zhao, Y; Xiong, X; Jia, L et al. · 2012 · Cell death & disease · DOI

Full title: Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis.

Authors: Zhao, Y; Xiong, X; Jia, L; Sun, Y

Year: 2012

Venue: Cell death & disease

DOI: https://doi.org/10.1038/cddis.2012.125

Paper The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.

Chen, Zhen-Hua; Wang, Wen-Tao; Huang, Wei et al. · 2017 · Cell death and differentiation · DOI

Full title: The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.

Authors: Chen, Zhen-Hua; Wang, Wen-Tao; Huang, Wei; Fang, Ke; Sun, Yu-Meng; Liu, Shu-Rong; Luo, Xue-Qun; Chen, Yue-Qin

Year: 2017

Venue: Cell death and differentiation

DOI: https://doi.org/10.1038/cdd.2016.111

Paper Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

Feng, Yijia; Ke, Changhong; Tang, Qianhan et al. · 2014 · Cell Death and Disease · DOI

Full title: Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

Authors: Feng, Yijia; Ke, Changhong; Tang, Qianhan; Dong, Hongmei; Zheng, Xiaoxuan; Lin, Wan‐Wan; Ke, Jun-An; Huang, Jiana; Yeung, Sai‐Ching J.; Zhang, H.

Year: 2014

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2014.59

Paper Ubiquitin modifications

Swatek, Kirby N.; Komander, David · 2016 · Cell Research · DOI

Full title: Ubiquitin modifications

Authors: Swatek, Kirby N.; Komander, David

Year: 2016

Venue: Cell Research

DOI: https://doi.org/10.1038/cr.2016.39

Paper Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway.

Nie, Tiejian; Yang, Shaosong; Ma, Hongwei et al. · 2016 · Cell death & disease · DOI

Full title: Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway.

Authors: Nie, Tiejian; Yang, Shaosong; Ma, Hongwei; Zhang, Lei; Lu, Fangfang; Tao, Kai; Wang, Ronglin; Yang, Ruixin; Huang, Lu; Mao, Zixu; Yang, Qian

Year: 2016

Venue: Cell death & disease

DOI: https://doi.org/10.1038/cddis.2016.423

Paper HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity.

Sami Saribas, A; Cicalese, Stephanie; Ahooyi, Taha Mohseni et al. · 2017 · Cell death & disease · DOI

Full title: HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity.

Authors: Sami Saribas, A; Cicalese, Stephanie; Ahooyi, Taha Mohseni; Khalili, Kamel; Amini, Shohreh; Sariyer, Ilker Kudret

Year: 2017

Venue: Cell death & disease

DOI: https://doi.org/10.1038/cddis.2016.467

Paper Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells

Yao, Zhuo; Xie, Fuhua; Li, Min et al. · 2017 · Cell Death and Disease · DOI

Full title: Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells

Authors: Yao, Zhuo; Xie, Fuhua; Li, Min; Liang, Zirui; Xu, Wenli; Yang, Jianhua; Liu, Chang; Li, Hongwangwang; Zhou, Hui; Qu, Liang‐Hu

Year: 2017

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2017.35

Paper Autophagy has a key role in the pathophysiology of schizophrenia

Merenlender‐Wagner, Avia; Malishkevich, Anna; Shemer, Zeev et al. · 2013 · Molecular Psychiatry · DOI

Full title: Autophagy has a key role in the pathophysiology of schizophrenia

Authors: Merenlender‐Wagner, Avia; Malishkevich, Anna; Shemer, Zeev; Udawela, Madhara; Gibbons, Andrew S.; Scarr, Elizabeth; Dean, Brian; Levine, Jay F.; Agam, Galila; Gozes, Illana

Year: 2013

Venue: Molecular Psychiatry

DOI: https://doi.org/10.1038/mp.2013.174

Paper TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

Hua, Fang; Li, Ke; Yu, Jiao-jiao et al. · 2015 · Nature Communications · DOI

Full title: TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

Authors: Hua, Fang; Li, Ke; Yu, Jiao-jiao; Lv, Xiao-Xi; Yan, Jun; Zhang, Xiao-Wei; Sun, Wei; Lin, Heng; Shang, Shuang; Wang, Feng; Cui, Bing; Mu, Rong; Huang, Bo; Jiang, Jian-Dong; Hu, Zhuo-Wei

Year: 2015

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms8951

Paper PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

Zhao, Yi; Wang, Wei; Guo, Shutao et al. · 2016 · Nature Communications · DOI

Full title: PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

Authors: Zhao, Yi; Wang, Wei; Guo, Shutao; Wang, Yuhua; Miao, Lei; Xiong, Yang; Huang, Leaf

Year: 2016

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms11822

Paper Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Sergin, Ismail; Evans, Trent D.; Zhang, Xiangyu et al. · 2017 · Nature Communications · DOI

Full title: Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Authors: Sergin, Ismail; Evans, Trent D.; Zhang, Xiangyu; Bhattacharya, Somashubhra; Stokes, Carl J.; Song, Eric; Ali, Sahl; Dehestani, Babak; Holloway, Karyn B.; Micevych, Paul S.; Javaheri, Ali; Crowley, Jan R.; Ballabio, Andrea; Schilling, Joel D.; Epelman, Slava; Weihl, Conrad C.; Diwan, Abhinav; Fan, Daping; Zayed, Mohamed A.; Razani, Babak

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms15750

Paper mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

Palmieri, Michela; Pal, Rituraj; Nelvagal, Hemanth R. et al. · 2017 · Nature Communications · DOI

Full title: mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

Authors: Palmieri, Michela; Pal, Rituraj; Nelvagal, Hemanth R.; Lotfi, Parisa; Stinnett, Gary; Seymour, Michelle L.; Chaudhury, Arindam; Bajaj, Lakshya; Bondar, Vitaliy V.; Bremner, Laura; Saleem, Usama; Tse, Dennis Y.; Sanagasetti, Deepthi; Wu, Samuel M.; Neilson, Joel R.; Pereira, Fred A.; Pautler, Robia G.; Rodney, George G.; Cooper, Jonathan D.; Sardiello, Marco

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms14338

Paper Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Ciechanover, Aaron; Kwon, Yong Tae · 2015 · Experimental & Molecular Medicine · DOI

Full title: Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Authors: Ciechanover, Aaron; Kwon, Yong Tae

Year: 2015

Venue: Experimental & Molecular Medicine

DOI: https://doi.org/10.1038/emm.2014.117

Paper Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches

Mary, Arnaud; Eysert, Fanny; Checler, Frédéric et al. · 2022 · Molecular Psychiatry · DOI

Full title: Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches

Authors: Mary, Arnaud; Eysert, Fanny; Checler, Frédéric; Chami, Mounia

Year: 2022

Venue: Molecular Psychiatry

DOI: https://doi.org/10.1038/s41380-022-01631-6

Paper Diversity and complexity of cell death: a historical review

Park, Mi-Ju; Wei, Shibo; Kim, Bosung et al. · 2023 · Experimental & Molecular Medicine · DOI

Full title: Diversity and complexity of cell death: a historical review

Authors: Park, Mi-Ju; Wei, Shibo; Kim, Bosung; Kim, Bosung; Bae, Sung‐Jin; Chae, Young Chan; Ryu, Dongryeol; Ha, Ki‐Tae

Year: 2023

Venue: Experimental & Molecular Medicine

DOI: https://doi.org/10.1038/s12276-023-01078-x

Paper The independence of and associations among apoptosis, autophagy, and necrosis

Chen, Qi; Kang, Jian; Fu, Caiyun · 2018 · Signal Transduction and Targeted Therapy · DOI

Full title: The independence of and associations among apoptosis, autophagy, and necrosis

Authors: Chen, Qi; Kang, Jian; Fu, Caiyun

Year: 2018

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-018-0018-5

Paper Recent advances in extracellular vesicles for therapeutic cargo delivery

Kim, Hyo In; Park, Jin Bong; Zhu, Yin et al. · 2024 · Experimental & Molecular Medicine · DOI

Full title: Recent advances in extracellular vesicles for therapeutic cargo delivery

Authors: Kim, Hyo In; Park, Jin Bong; Zhu, Yin; Wang, Xiaoyun; Han, Yohan; Zhang, Duo

Year: 2024

Venue: Experimental & Molecular Medicine

DOI: https://doi.org/10.1038/s12276-024-01201-6

Paper Targeting circular RNAs as a therapeutic approach: current strategies and challenges

He, Alina T.; Liu, Jinglei; Li, Feiya et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Targeting circular RNAs as a therapeutic approach: current strategies and challenges

Authors: He, Alina T.; Liu, Jinglei; Li, Feiya; Yang, Burton B.

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00569-5

Paper Ferroptosis: mechanisms and links with diseases

Yan, Hong-Fa; Zou, Ting; Tuo, Qing‐zhang et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Ferroptosis: mechanisms and links with diseases

Authors: Yan, Hong-Fa; Zou, Ting; Tuo, Qing‐zhang; Xu, Shuo; Li, Hua; Belaidi, Abdel Ali; Lei, Peng

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-020-00428-9

Paper Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions

Xu, Dong-Chen; Chen, Yong; Xu, Yang et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions

Authors: Xu, Dong-Chen; Chen, Yong; Xu, Yang; Chen-Yu, ShenTu; Peng, Li‐Hua

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01353-3

Paper Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.

Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante et al. · 2018 · Cell death & disease · DOI

Full title: Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.

Authors: Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante; Lucidi, Alessia; Salvati, Erica; Zizza, Pasquale; Di Leo, Luca; Del Bufalo, Donatella; Ciriolo, Maria Rosa; Leonetti, Carlo; Steegborn, Clemens; Mai, Antonello; Rizzo, Angela; Biroccio, Annamaria

Year: 2018

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-018-1065-0

Paper PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

Zhou, Di; Zhou, Meng; Wang, Ziying et al. · 2019 · Cell Death and Disease · DOI

Full title: PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

Authors: Zhou, Di; Zhou, Meng; Wang, Ziying; Fu, Yi; Jia, Meng; Wang, Xiaojie; Liu, Min; Zhang, Yan; Sun, Yu; Lu, Yi; Tang, Wei; Yi, Fan

Year: 2019

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-019-1754-3

Paper Apatinib-induced protective autophagy and apoptosis through the AKT–mTOR pathway in anaplastic thyroid cancer

Feng, Haoran; Cheng, Xi; Kuang, Jie et al. · 2018 · Cell Death and Disease · DOI

Full title: Apatinib-induced protective autophagy and apoptosis through the AKT–mTOR pathway in anaplastic thyroid cancer

Authors: Feng, Haoran; Cheng, Xi; Kuang, Jie; Chen, Lingxie; Yuen, Stanley; Shi, Minmin; Liang, Juyong; Shen, Baiyong; Jin, Zhijian; Yan, Jiqi; Qiu, Weihua

Year: 2018

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-018-1054-3

Paper Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy.

Peng, Yonghan; Yang, Cheng; Shi, Xiaolei et al. · 2019 · Cell death & disease · DOI

Full title: Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy.

Authors: Peng, Yonghan; Yang, Cheng; Shi, Xiaolei; Li, Ling; Dong, Hao; Liu, Changcheng; Fang, Ziyu; Wang, Zeyu; Ming, Shaoxiong; Liu, Min; Xie, Bin; Gao, Xiaofeng; Sun, Yinghao

Year: 2019

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-018-1169-6

Paper Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells.

Cristofani, Riccardo; Montagnani Marelli, Marina; Cicardi, Maria Elena et al. · 2018 · Cell death & disease · DOI

Full title: Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells.

Authors: Cristofani, Riccardo; Montagnani Marelli, Marina; Cicardi, Maria Elena; Fontana, Fabrizio; Marzagalli, Monica; Limonta, Patrizia; Poletti, Angelo; Moretti, Roberta Manuela

Year: 2018

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-018-0866-5

Paper The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression.

Shu, Xiaodong; Sun, Yiming; Sun, Xiyang et al. · 2019 · Cell death & disease · DOI

Full title: The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression.

Authors: Shu, Xiaodong; Sun, Yiming; Sun, Xiyang; Zhou, Yuanzhang; Bian, Yaqi; Shu, Zhaoma; Ding, Jianhua; Lu, Ming; Hu, Gang

Year: 2019

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-019-1813-9

Paper Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.

Qiu, Qian-Qi; Zhang, Na; Xu, Ying-Yi et al. · 2026 · Molecular medicine reports · DOI

Full title: Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.

Authors: Qiu, Qian-Qi; Zhang, Na; Xu, Ying-Yi; Qin, Jing-Wen; Yu, Gao-Feng; Song, Xing-Rong

Year: 2026

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2025.13784

Paper Enhancement of oxaliplatin-induced cell apoptosis and tumor suppression by 3-methyladenine in colon cancer.

Tan, Shisheng; Peng, Xingchen; Peng, Wen et al. · 2015 · Oncology letters · DOI

Full title: Enhancement of oxaliplatin-induced cell apoptosis and tumor suppression by 3-methyladenine in colon cancer.

Authors: Tan, Shisheng; Peng, Xingchen; Peng, Wen; Zhao, Yinglan; Wei, Yuquan

Year: 2015

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2015.2996

Paper Dual Inhibition of PI3K/Akt/mTOR Pathway and Role of Autophagy in Non-Small Cell Lung Cancer Cells.

Jeong, Eun-Hui; Choi, Hyeong Sim; Lee, Tae-Gul et al. · 2012 · Tuberculosis and respiratory diseases · DOI

Full title: Dual Inhibition of PI3K/Akt/mTOR Pathway and Role of Autophagy in Non-Small Cell Lung Cancer Cells.

Authors: Jeong, Eun-Hui; Choi, Hyeong Sim; Lee, Tae-Gul; Kim, Hye-Ryoun; Kim, Cheol Hyeon

Year: 2012

Venue: Tuberculosis and respiratory diseases

DOI: https://doi.org/10.4046/trd.2012.72.4.343

Paper Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy.

Chen, Menghui; Liu, Su · 2024 · European journal of histochemistry : EJH · DOI

Full title: Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy.

Authors: Chen, Menghui; Liu, Su

Year: 2024

Venue: European journal of histochemistry : EJH

DOI: https://doi.org/10.4081/ejh.2024.3983

Paper Tremella fuciformis polysaccharide: enhancing ischemic hypoxic adaptation of mesenchymal stem cells.

Yang, Lei; Chen, Shan; Zhao, Gang et al. · 2025 · European journal of translational myology · DOI

Full title: Tremella fuciformis polysaccharide: enhancing ischemic hypoxic adaptation of mesenchymal stem cells.

Authors: Yang, Lei; Chen, Shan; Zhao, Gang; Gou, Wei; Wang, Weiwei; Hu, Zhipeng

Year: 2025

Venue: European journal of translational myology

DOI: https://doi.org/10.4081/ejtm.2025.14289

Paper Platelet rich plasma alleviates OGD/R injury in N2a cell by enhancing autophagy through the miR‑223/PAQR3 pathway.

Yang, Li-Ting; Li, Li-Hua; Peng, Wen-Na · 2022 · Acta neurobiologiae experimentalis · DOI

Full title: Platelet rich plasma alleviates OGD/R injury in N2a cell by enhancing autophagy through the miR‑223/PAQR3 pathway.

Authors: Yang, Li-Ting; Li, Li-Hua; Peng, Wen-Na

Year: 2022

Venue: Acta neurobiologiae experimentalis

DOI: https://doi.org/10.55782/ane-2022-011

Paper Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in rats with allergic rhinitis.

Mei, Jinyu; Kong, Hua; Zhao, Zhentao et al. · 2020 · Bioscience trends · DOI

Full title: Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in rats with allergic rhinitis.

Authors: Mei, Jinyu; Kong, Hua; Zhao, Zhentao; Chen, Ziyu; Wang, Yatang; Yang, Jianming

Year: 2020

Venue: Bioscience trends

DOI: https://doi.org/10.5582/bst.2019.01332

Paper [Multiple system atrophy and autophagy].

Wakabayashi, Koichi; Tanji, Kunikazu · 2014 · Rinsho shinkeigaku = Clinical neurology · DOI

Full title: [Multiple system atrophy and autophagy].

Authors: Wakabayashi, Koichi; Tanji, Kunikazu

Year: 2014

Venue: Rinsho shinkeigaku = Clinical neurology

DOI: https://doi.org/10.5692/clinicalneurol.54.966

Paper A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan.

Hu, Xiqi; Peng, Jun; Tang, Wei et al. · 2023 · Bioscience trends · DOI

Full title: A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan.

Authors: Hu, Xiqi; Peng, Jun; Tang, Wei; Xia, Ying; Song, Peipei

Year: 2023

Venue: Bioscience trends

DOI: https://doi.org/10.5582/bst.2023.01221

Paper FOXO1-mediated nuclear sequestration of STAT3 and AKT1 triggers FOXO3-dependent autophagic death in hypoxic granulosa cells.

Li, Chengyu; Wu, Gang; Ning, Caibo et al. · 2024 · International journal of biological sciences · DOI

Full title: FOXO1-mediated nuclear sequestration of STAT3 and AKT1 triggers FOXO3-dependent autophagic death in hypoxic granulosa cells.

Authors: Li, Chengyu; Wu, Gang; Ning, Caibo; Liu, Zhaojun; Tao, Jingli; Lu, Xiumei; Shen, Ming; Liu, Honglin

Year: 2024

Venue: International journal of biological sciences

DOI: https://doi.org/10.7150/ijbs.101309

Paper Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma

Li, Bo; Zhou, Pingting; Xu, Kehan et al. · 2019 · International Journal of Biological Sciences · DOI

Full title: Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma

Authors: Li, Bo; Zhou, Pingting; Xu, Kehan; Chen, Tianrui; Jiao, Jian; Wei, Haifeng; Yang, Xinghai; Xu, Wei; Wan, Wei; Xiao, Jianru

Year: 2019

Venue: International Journal of Biological Sciences

DOI: https://doi.org/10.7150/ijbs.33787

Paper Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.

Wang, Xuejing; Ma, Mingming; Teng, Junfang et al. · 2015 · International journal of biological sciences · DOI

Full title: Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.

Authors: Wang, Xuejing; Ma, Mingming; Teng, Junfang; Che, Xiangqian; Zhang, Wenwen; Feng, Shuman; Zhou, Shuang; Zhang, Ying; Wu, Erxi; Ding, Xuebing

Year: 2015

Venue: International journal of biological sciences

DOI: https://doi.org/10.7150/ijbs.11880

Paper SIRT6 ameliorates LPS-induced apoptosis and tight junction injury in ARDS through the ERK1/2 pathway and autophagy.

Liu, Hanhan; Wang, Sijiao; Gong, Linjing et al. · 2023 · International journal of medical sciences · DOI

Full title: SIRT6 ameliorates LPS-induced apoptosis and tight junction injury in ARDS through the ERK1/2 pathway and autophagy.

Authors: Liu, Hanhan; Wang, Sijiao; Gong, Linjing; Shen, Yue; Xu, Fan; Wang, Yali; Hu, Lijuan; Zhu, Lei

Year: 2023

Venue: International journal of medical sciences

DOI: https://doi.org/10.7150/ijms.80920

Paper Ursolic Acid Alleviates Mitotic Catastrophe in Podocyte by Inhibiting Autophagic P62 Accumulation in Diabetic Nephropathy.

Mei, Hang; Jing, Tienan; Liu, Haojun et al. · 2024 · International journal of biological sciences · DOI

Full title: Ursolic Acid Alleviates Mitotic Catastrophe in Podocyte by Inhibiting Autophagic P62 Accumulation in Diabetic Nephropathy.

Authors: Mei, Hang; Jing, Tienan; Liu, Haojun; Liu, Yue; Zhu, Xinwang; Wang, Jiao; Xu, Li

Year: 2024

Venue: International journal of biological sciences

DOI: https://doi.org/10.7150/ijbs.94096

Paper Heterophyllin B enhances transcription factor EB-mediated autophagy and alleviates pyroptosis and oxidative stress after spinal cord injury.

Zhang, Haojie; Wang, Wei; Hu, Xinli et al. · 2024 · International journal of biological sciences · DOI

Full title: Heterophyllin B enhances transcription factor EB-mediated autophagy and alleviates pyroptosis and oxidative stress after spinal cord injury.

Authors: Zhang, Haojie; Wang, Wei; Hu, Xinli; Wang, Zheng; Lou, Junsheng; Cui, Peng; Zhao, Xuan; Wang, Yu; Chen, Xiaolong; Lu, Shibao

Year: 2024

Venue: International journal of biological sciences

DOI: https://doi.org/10.7150/ijbs.97669

Paper Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.

Cai, Cui-Zan; Zhuang, Xu-Xu; Zhu, Qi et al. · 2022 · Theranostics · DOI

Full title: Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.

Authors: Cai, Cui-Zan; Zhuang, Xu-Xu; Zhu, Qi; Wu, Ming-Yue; Su, Huanxing; Wang, Xiao-Jin; Iyaswamy, Ashok; Yue, Zhenyu; Wang, Qian; Zhang, Bin; Xue, Yu; Tan, Jieqiong; Li, Min; He, Huanhuan; Lu, Jia-Hong

Year: 2022

Venue: Theranostics

DOI: https://doi.org/10.7150/thno.64148

Paper Unlocking the Therapeutic Potential: Harnessing miR-125a-5p To Enhance Autophagy and Apoptosis in Pancreatic Cancer through Targeting STAT3.

Pan, Lujuan; Qin, Zongshuai; Zhou, Qinghong et al. · 2024 · Journal of Cancer · DOI

Full title: Unlocking the Therapeutic Potential: Harnessing miR-125a-5p To Enhance Autophagy and Apoptosis in Pancreatic Cancer through Targeting STAT3.

Authors: Pan, Lujuan; Qin, Zongshuai; Zhou, Qinghong; Zheng, Pin; Li, Hua; Zhou, Xihan; Qin, Yueqiu

Year: 2024

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.97102

Paper Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

Chen, Sheng; Gan, Donghao; Lin, Sixiong et al. · 2022 · Theranostics · DOI

Full title: Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

Authors: Chen, Sheng; Gan, Donghao; Lin, Sixiong; Zhong, Yiming; Chen, Mingjue; Zou, Xuenong; Shao, Zengwu; Xiao, Guozhi

Year: 2022

Venue: Theranostics

DOI: https://doi.org/10.7150/thno.71360

Paper Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.

Chen, Meng-Lu; Hong, Chun-Gu; Yue, Tao et al. · 2021 · Theranostics · DOI

Full title: Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.

Authors: Chen, Meng-Lu; Hong, Chun-Gu; Yue, Tao; Li, Hong-Ming; Duan, Ran; Hu, Wen-Bao; Cao, Jia; Wang, Zhen-Xing; Chen, Chun-Yuan; Hu, Xiong-Ke; Wu, Ben; Liu, Hao-Ming; Tan, Yi-Juan; Liu, Jiang-Hua; Luo, Zhong-Wei; Zhang, Yan; Rao, Shan-Shan; Luo, Ming-Jie; Yin, Hao; Wang, Yi-Yi; Xia, Kun; Tang, Si-Yuan; Xie, Hui; Liu, Zheng-Zhao

Year: 2021

Venue: Theranostics

DOI: https://doi.org/10.7150/thno.47408

Paper Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

Ciscato, Francesco; Ferrone, Lavinia; Masgras, Ionica et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

Authors: Ciscato, Francesco; Ferrone, Lavinia; Masgras, Ionica; Laquatra, Claudio; Rasola, Andrea

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22094716

Paper Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease

Sharma, Chanchal; Kim, Sehwan; Nam, Youngpyo et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease

Authors: Sharma, Chanchal; Kim, Sehwan; Nam, Youngpyo; Jung, Un Ju; Kim, Sang Ryong; Kim, Sang Ryong; Kim, Sang Ryong

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22094850

Paper The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway

Liu, Juan; Zhang, Cen; Wang, Jianming et al. · 2020 · International Journal of Molecular Sciences · DOI

Full title: The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway

Authors: Liu, Juan; Zhang, Cen; Wang, Jianming; Hu, Wenwei; Feng, Zhaohui

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21218387

Paper Interplay between Autophagy and Herpes Simplex Virus Type 1: ICP34.5, One of the Main Actors.

Ripa, Inés; Andreu, Sabina; López-Guerrero, José Antonio et al. · 2022 · International journal of molecular sciences · DOI

Full title: Interplay between Autophagy and Herpes Simplex Virus Type 1: ICP34.5, One of the Main Actors.

Authors: Ripa, Inés; Andreu, Sabina; López-Guerrero, José Antonio; Bello-Morales, Raquel

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232113643

Paper Suffruticosol B Is an Osteogenic Inducer through Osteoblast Differentiation, Autophagy, Adhesion, and Migration.

Yun, Hyung-Mun; Lee, Joon Yeop; Kim, Bomi et al. · 2022 · International journal of molecular sciences · DOI

Full title: Suffruticosol B Is an Osteogenic Inducer through Osteoblast Differentiation, Autophagy, Adhesion, and Migration.

Authors: Yun, Hyung-Mun; Lee, Joon Yeop; Kim, Bomi; Park, Kyung-Ran

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232113559

Paper Functional Relationships between L1CAM, LC3, ATG12, and Aβ.

Loers, Gabriele; Bork, Ute; Schachner, Melitta · 2024 · International journal of molecular sciences · DOI

Full title: Functional Relationships between L1CAM, LC3, ATG12, and Aβ.

Authors: Loers, Gabriele; Bork, Ute; Schachner, Melitta

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms251910829

Paper Neuroprotection of Andrographolide against Neurotoxin MPP+-Induced Apoptosis in SH-SY5Y Cells via Activating Mitophagy, Autophagy, and Antioxidant Activities.

Prasertsuksri, Prachayaporn; Kraokaew, Pichnaree; Pranweerapaiboon, Kanta et al. · 2023 · International journal of molecular sciences · DOI

Full title: Neuroprotection of Andrographolide against Neurotoxin MPP+-Induced Apoptosis in SH-SY5Y Cells via Activating Mitophagy, Autophagy, and Antioxidant Activities.

Authors: Prasertsuksri, Prachayaporn; Kraokaew, Pichnaree; Pranweerapaiboon, Kanta; Sobhon, Prasert; Chaithirayanon, Kulathida

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24108528

Paper Phosphorylated Tau in Alzheimer’s Disease and Other Tauopathies

Rawat, Priyanka; Sehar, Ujala; Bisht, Jasbir et al. · 2022 · International Journal of Molecular Sciences · DOI

Full title: Phosphorylated Tau in Alzheimer’s Disease and Other Tauopathies

Authors: Rawat, Priyanka; Sehar, Ujala; Bisht, Jasbir; Selman, Ashley; Culberson, John; Reddy, P. Hemachandra

Year: 2022

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms232112841

Paper Tat-Beclin-1 Peptide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Enhancing Hepatic Autophagy.

Chen, Chun-Liang; Huang, Fen-Fen; Lin, Hsueh-Fang et al. · 2024 · International journal of molecular sciences · DOI

Full title: Tat-Beclin-1 Peptide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Enhancing Hepatic Autophagy.

Authors: Chen, Chun-Liang; Huang, Fen-Fen; Lin, Hsueh-Fang; Wu, Chi-Chien; Ni, Yen-Hsuan; Lin, Yu-Cheng

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252212372

Paper CK and LRRK2 Involvement in Neurodegenerative Diseases.

Bova, Valentina; Mannino, Deborah; Capra, Anna Paola et al. · 2024 · International journal of molecular sciences · DOI

Full title: CK and LRRK2 Involvement in Neurodegenerative Diseases.

Authors: Bova, Valentina; Mannino, Deborah; Capra, Anna Paola; Lanza, Marika; Palermo, Nicoletta; Filippone, Alessia; Esposito, Emanuela

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252111661

Paper Protective Effects of Ambroxol on Aβ and α-Synuclein-Induced Neurotoxicity Through Glucocerebrosidase Activation in HT-22 Hippocampal Neuronal Cells.

Lin, Sheng-Chieh; Chang, Ching-Chi; Tsou, Sing-Hua et al. · 2024 · International journal of molecular sciences · DOI

Full title: Protective Effects of Ambroxol on Aβ and α-Synuclein-Induced Neurotoxicity Through Glucocerebrosidase Activation in HT-22 Hippocampal Neuronal Cells.

Authors: Lin, Sheng-Chieh; Chang, Ching-Chi; Tsou, Sing-Hua; Chiu, Pai-Yi; Cheng, Ju-Fang; Hung, Hui-Chih; Chen, Wei-Jen; Ho, Ying-Jui; Lin, Chih-Li

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252212114

Paper Modulating Autophagy in Osteoarthritis: Exploring Emerging Therapeutic Drug Targets.

Andrei, Corina; Mihai, Dragos Paul; Nitulescu, George Mihai et al. · 2024 · International journal of molecular sciences · DOI

Full title: Modulating Autophagy in Osteoarthritis: Exploring Emerging Therapeutic Drug Targets.

Authors: Andrei, Corina; Mihai, Dragos Paul; Nitulescu, George Mihai; Nitulescu, Georgiana; Zanfirescu, Anca

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252413695

Paper Interaction Between CsATG8f and CsRAP2.12 Modulates Antioxidant Defense and Hypoxia Response During Submergence in Camellia sinensis.

Zeng, Rou; Liu, Yun; Yu, Lisha et al. · 2025 · International journal of molecular sciences · DOI

Full title: Interaction Between CsATG8f and CsRAP2.12 Modulates Antioxidant Defense and Hypoxia Response During Submergence in Camellia sinensis.

Authors: Zeng, Rou; Liu, Yun; Yu, Lisha; Lei, Xiaogang; Jiang, Jie; Shen, Qiang; Ma, Yuanchun; Fang, Wanping; Zhu, Xujun

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms27010235

Paper Bromodomain and Extraterminal Domain (BET) Protein Inhibition Hinders Glioblastoma Progression by Inducing Autophagy-Dependent Differentiation.

Colardo, Mayra; Gargano, Deborah; Russo, Miriam et al. · 2023 · International journal of molecular sciences · DOI

Full title: Bromodomain and Extraterminal Domain (BET) Protein Inhibition Hinders Glioblastoma Progression by Inducing Autophagy-Dependent Differentiation.

Authors: Colardo, Mayra; Gargano, Deborah; Russo, Miriam; Petraroia, Michele; Pensabene, Daniele; D'Alessandro, Giuseppina; Santoro, Antonio; Limatola, Cristina; Segatto, Marco; Di Bartolomeo, Sabrina

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24087017

Paper Impact of Benzo(a)pyrene and Pyrene Exposure on Activating Autophagy and Correlation with Endoplasmic Reticulum Stress in Human Astrocytes.

Siangcham, Tanapan; Vivithanaporn, Pornpun; Jantakee, Kanyaluck et al. · 2025 · International journal of molecular sciences · DOI

Full title: Impact of Benzo(a)pyrene and Pyrene Exposure on Activating Autophagy and Correlation with Endoplasmic Reticulum Stress in Human Astrocytes.

Authors: Siangcham, Tanapan; Vivithanaporn, Pornpun; Jantakee, Kanyaluck; Ruangtong, Jittiporn; Thongsepee, Nattaya; Martviset, Pongsakorn; Chantree, Pathanin; Sornchuer, Phornphan; Sangpairoj, Kant

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26041748

Paper p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy.

Trouvé, Pascal; Férec, Claude · 2025 · International journal of molecular sciences · DOI

Full title: p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy.

Authors: Trouvé, Pascal; Férec, Claude

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26083623

Paper Non-Structural Protein V of Canine Distemper Virus Induces Autophagy via PI3K/AKT/mTOR Pathway to Facilitate Viral Replication.

Tian, Xin; Zhang, Rui; Yi, Shuang et al. · 2024 · International journal of molecular sciences · DOI

Full title: Non-Structural Protein V of Canine Distemper Virus Induces Autophagy via PI3K/AKT/mTOR Pathway to Facilitate Viral Replication.

Authors: Tian, Xin; Zhang, Rui; Yi, Shuang; Chen, Yu; Jiang, Ying; Zhang, Xianwen; Zhang, Zhidong; Li, Yanmin

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26010084

Paper Comparative Analysis of Two Autophagy-Enhancing Small Molecules (AUTEN-67 and -99) in a Drosophila Model of Spinocerebellar Ataxia Type 1.

Burján, Tímea; Aslam, Maryam; Keresztes, Fanni et al. · 2025 · International journal of molecular sciences · DOI

Full title: Comparative Analysis of Two Autophagy-Enhancing Small Molecules (AUTEN-67 and -99) in a Drosophila Model of Spinocerebellar Ataxia Type 1.

Authors: Burján, Tímea; Aslam, Maryam; Keresztes, Fanni; Sigmond, Tímea; Billes, Viktor A; Bencsik, Norbert; Schlett, Katalin; Vellai, Tibor; Kovács, Tibor

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms262110443

Paper Molecular Mechanisms and Therapeutic Perspectives of Gut Microbiota, Autophagy, and Apoptosis in Cholangiocarcinoma Pathophysiology.

Ruiz-Pozo, Viviana A; Cadena-Ullauri, Santiago; Guevara-Ramírez, Patricia et al. · 2025 · International journal of molecular sciences · DOI

Full title: Molecular Mechanisms and Therapeutic Perspectives of Gut Microbiota, Autophagy, and Apoptosis in Cholangiocarcinoma Pathophysiology.

Authors: Ruiz-Pozo, Viviana A; Cadena-Ullauri, Santiago; Guevara-Ramírez, Patricia; Tamayo-Trujillo, Rafael; Paz-Cruz, Elius; Cabrera-Andrade, Alejandro; Zambrano, Ana Karina

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26209949

Paper Conditional Overexpression of Neuritin in Supporting Cell Protects Cochlear Hair Cell and Delays Age-Related Hearing Loss by Enhancing Autophagy.

Wang, Shanshan; Lv, Shaowei; Hu, Junhao et al. · 2025 · International journal of molecular sciences · DOI

Full title: Conditional Overexpression of Neuritin in Supporting Cell Protects Cochlear Hair Cell and Delays Age-Related Hearing Loss by Enhancing Autophagy.

Authors: Wang, Shanshan; Lv, Shaowei; Hu, Junhao; Shi, Yunfan; Li, Yu; Zhang, Jianyun; Tan, Xiaohua; Chen, Rong; Hong, Yu

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26083709

Paper Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation.

Chen, Jiaxi; Zhang, Jieping; Cai, Lijuan et al. · 2024 · Marine drugs · DOI

Full title: Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation.

Authors: Chen, Jiaxi; Zhang, Jieping; Cai, Lijuan; Guo, Li; Cai, Zhenyu; Han, Hua; Zhang, Wen

Year: 2024

Venue: Marine drugs

DOI: https://doi.org/10.3390/md22040174

Paper Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.

Ma, Teng; Wang, Xiangpeng; Qu, Wenjing et al. · 2022 · Molecules (Basel, Switzerland) · DOI

Full title: Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.

Authors: Ma, Teng; Wang, Xiangpeng; Qu, Wenjing; Yang, Lingsen; Jing, Cheng; Zhu, Bingrui; Zhang, Yongkui; Xie, Wenpeng

Year: 2022

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules27238624

Paper Role of Autophagy on Heavy Metal-Induced Renal Damage and the Protective Effects of Curcumin in Autophagy and Kidney Preservation.

Avila-Rojas, Sabino Hazael; Lira-León, Alejandra; Aparicio-Trejo, Omar Emiliano et al. · 2019 · Medicina (Kaunas, Lithuania) · DOI

Full title: Role of Autophagy on Heavy Metal-Induced Renal Damage and the Protective Effects of Curcumin in Autophagy and Kidney Preservation.

Authors: Avila-Rojas, Sabino Hazael; Lira-León, Alejandra; Aparicio-Trejo, Omar Emiliano; Reyes-Fermín, Laura María; Pedraza-Chaverri, José

Year: 2019

Venue: Medicina (Kaunas, Lithuania)

DOI: https://doi.org/10.3390/medicina55070360

Paper Natural Neurobiological Active Compounds in Parkinson's Disease: Molecular Targets, Signaling Pathways, and Therapeutic Prospects.

Wu, Xue; Zhang, Linao; Luo, Shifang et al. · 2026 · International journal of molecular sciences · DOI

Full title: Natural Neurobiological Active Compounds in Parkinson's Disease: Molecular Targets, Signaling Pathways, and Therapeutic Prospects.

Authors: Wu, Xue; Zhang, Linao; Luo, Shifang; Li, Qing; Wang, Jiying; Chen, Wentao; Zhou, Na; Zhou, Lingli; Li, Rongyu; Xie, Yuhuan; Chen, Qinghua; Guo, Peixin

Year: 2026

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms27031301

Paper Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?

Smoliga, James M.; Blanchard, Otis L. · 2014 · Molecules · DOI

Full title: Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?

Authors: Smoliga, James M.; Blanchard, Otis L.

Year: 2014

Venue: Molecules

DOI: https://doi.org/10.3390/molecules191117154

Paper Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy.

Zhou, Ping; Xie, Weijie; Luo, Yun et al. · 2018 · Molecules (Basel, Switzerland) · DOI

Full title: Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy.

Authors: Zhou, Ping; Xie, Weijie; Luo, Yun; Lu, Shan; Dai, Ziru; Wang, Ruiying; Zhang, Xuelian; Li, Guang; Sun, Guibo; Sun, Xiaobo

Year: 2018

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules23112912

Paper Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy.

Zhang, Qi; Zhou, Jing; Shen, Mi et al. · 2020 · Molecules (Basel, Switzerland) · DOI

Full title: Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy.

Authors: Zhang, Qi; Zhou, Jing; Shen, Mi; Xu, Hui; Yu, Shu; Cheng, Qiong; Ding, Fei

Year: 2020

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules25194359

Paper Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

Kou, Xianjuan; Li, Biao; Olayanju, Julia B. et al. · 2018 · Nutrients · DOI

Full title: Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

Authors: Kou, Xianjuan; Li, Biao; Olayanju, Julia B.; Drake, Justin M.; Chen, Ning

Year: 2018

Venue: Nutrients

DOI: https://doi.org/10.3390/nu10030343

Paper Flavonoids as Anticancer Agents

Kopustinskienė, Dalia M.; Jakštas, Valdas; Savickas, Arūnas et al. · 2020 · Nutrients · DOI

Full title: Flavonoids as Anticancer Agents

Authors: Kopustinskienė, Dalia M.; Jakštas, Valdas; Savickas, Arūnas; Bernatonienė, Jurga

Year: 2020

Venue: Nutrients

DOI: https://doi.org/10.3390/nu12020457

Paper Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson's Disease Model.

Azam, Shofiul; Haque, Md Ezazul; Cho, Duk-Yeon et al. · 2022 · Molecules (Basel, Switzerland) · DOI

Full title: Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson's Disease Model.

Authors: Azam, Shofiul; Haque, Md Ezazul; Cho, Duk-Yeon; Kim, Joon-Soo; Jakaria, Md; Kim, In-Su; Choi, Dong-Kug

Year: 2022

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules27092827

Paper Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer-Mechanisms and Clinical Implications for Natural Products.

Warias, Paulina; Plewa, Paulina; Poniewierska-Baran, Agata · 2024 · Molecules (Basel, Switzerland) · DOI

Full title: Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer-Mechanisms and Clinical Implications for Natural Products.

Authors: Warias, Paulina; Plewa, Paulina; Poniewierska-Baran, Agata

Year: 2024

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules30010003

Paper Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives

Xu, Xiaoyu; Meng, Xiao; Li, Sha et al. · 2018 · Nutrients · DOI

Full title: Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives

Authors: Xu, Xiaoyu; Meng, Xiao; Li, Sha; Gan, Ren‐You; Li, Ya; Li, Hua‐Bin

Year: 2018

Venue: Nutrients

DOI: https://doi.org/10.3390/nu10101553

Paper Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.

Chin, Kok-Yong; Pang, Kok-Lun · 2017 · Nutrients · DOI

Full title: Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.

Authors: Chin, Kok-Yong; Pang, Kok-Lun

Year: 2017

Venue: Nutrients

DOI: https://doi.org/10.3390/nu9101060

Paper Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.

Zhong, Yujie; Jin, Ruyi; Luo, Ruilin et al. · 2023 · Nutrients · DOI

Full title: Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.

Authors: Zhong, Yujie; Jin, Ruyi; Luo, Ruilin; Liu, Jiayu; Ren, Luting; Zhang, Yinghan; Shan, Zhongguo; Peng, Xiaoli

Year: 2023

Venue: Nutrients

DOI: https://doi.org/10.3390/nu15163554

Paper Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Ribeiro, Paulo Renato; Ferreira, Carmen; Antunes, Carlos et al. · 2025 · Nutrients · DOI

Full title: Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Authors: Ribeiro, Paulo Renato; Ferreira, Carmen; Antunes, Carlos; Dias, Gonçalo; Lima, Maria João; Guiné, Raquel; Teixeira-Lemos, Edite

Year: 2025

Venue: Nutrients

DOI: https://doi.org/10.3390/nu17213344

Paper Autophagy-Enhancing Properties of Hedyotis diffusa Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient.

Zheng, Qiwen; Jin, Xiangji; Nguyen, Trang Thi Minh et al. · 2025 · Molecules (Basel, Switzerland) · DOI

Full title: Autophagy-Enhancing Properties of Hedyotis diffusa Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient.

Authors: Zheng, Qiwen; Jin, Xiangji; Nguyen, Trang Thi Minh; Yi, Eun-Ji; Park, Se-Jig; Yi, Gyeong-Seon; Yang, Su-Jin; Yi, Tae-Hoo

Year: 2025

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules30020261

Paper The Emerging Role of Autophagy as a Target of Environmental Pollutants: An Update on Mechanisms.

Rahman, Md Ataur; Rahman, Md Saidur; Parvez, Md Anowar Khasru et al. · 2023 · Toxics · DOI

Full title: The Emerging Role of Autophagy as a Target of Environmental Pollutants: An Update on Mechanisms.

Authors: Rahman, Md Ataur; Rahman, Md Saidur; Parvez, Md Anowar Khasru; Kim, Bonglee

Year: 2023

Venue: Toxics

DOI: https://doi.org/10.3390/toxics11020135

Paper From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1.

Law, Martin; Wang, Pei-Chun; Zhou, Zhong-Yan et al. · 2024 · Pharmaceuticals (Basel, Switzerland) · DOI

Full title: From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1.

Authors: Law, Martin; Wang, Pei-Chun; Zhou, Zhong-Yan; Wang, Yu

Year: 2024

Venue: Pharmaceuticals (Basel, Switzerland)

DOI: https://doi.org/10.3390/ph17111495

Paper Biological Activity of Berberine—A Summary Update

Och, Anna; Podgórski, Rafał; Nowak, Renata · 2020 · Toxins · DOI

Full title: Biological Activity of Berberine—A Summary Update

Authors: Och, Anna; Podgórski, Rafał; Nowak, Renata

Year: 2020

Venue: Toxins

DOI: https://doi.org/10.3390/toxins12110713

Paper Pharmaceutical Agents for Targeting Autophagy and Their Applications in Clinics.

Kench, Ulash; Sologova, Susanna; Smolyarchuk, Elena et al. · 2024 · Pharmaceuticals (Basel, Switzerland) · DOI

Full title: Pharmaceutical Agents for Targeting Autophagy and Their Applications in Clinics.

Authors: Kench, Ulash; Sologova, Susanna; Smolyarchuk, Elena; Prassolov, Vladimir; Spirin, Pavel

Year: 2024

Venue: Pharmaceuticals (Basel, Switzerland)

DOI: https://doi.org/10.3390/ph17101355

Paper Maintenance of chaperone-mediated autophagy activity in cultured cells expressing mutant huntingtin.

Li, Xiang; Wang, Jianbin · 2014 · Biomedical reports · DOI

Full title: Maintenance of chaperone-mediated autophagy activity in cultured cells expressing mutant huntingtin.

Authors: Li, Xiang; Wang, Jianbin

Year: 2014

Venue: Biomedical reports

DOI: https://doi.org/10.3892/br.2014.278

Paper Autophagic Degradation of GPX4 Mediates Ferroptosis During Sheep Sperm Cryopreservation.

Li, Boyuan; Hai, Erhan; Song, Yukun et al. · 2025 · Veterinary sciences · DOI

Full title: Autophagic Degradation of GPX4 Mediates Ferroptosis During Sheep Sperm Cryopreservation.

Authors: Li, Boyuan; Hai, Erhan; Song, Yukun; Zhang, Jiaxin

Year: 2025

Venue: Veterinary sciences

DOI: https://doi.org/10.3390/vetsci12050490

Paper 5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.

Xu, Ningqin; Huang, Ju; Wang, Yiming et al. · 2025 · Acta biochimica et biophysica Sinica · DOI

Full title: 5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.

Authors: Xu, Ningqin; Huang, Ju; Wang, Yiming; Liu, Yaxin; Jiang, Yangwei; Zhou, Wei; Sheng, Jinghao; Zhang, Lahong

Year: 2025

Venue: Acta biochimica et biophysica Sinica

DOI: https://doi.org/10.3724/abbs.2025074

Paper Ononin alleviates H2O2-induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autophagy pathway.

Pan, Rongrong; Zhuang, Qin; Wang, Jiangtin · 2021 · Experimental and therapeutic medicine · DOI

Full title: Ononin alleviates H2O2-induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autophagy pathway.

Authors: Pan, Rongrong; Zhuang, Qin; Wang, Jiangtin

Year: 2021

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2021.10742

Paper Puerarin promotes the viability and differentiation of MC3T3-E1 cells by enhancing LC3B-mediated autophagy through downregulation of miR-204.

Feng, Qian; Cheng, Song-Yi; Yang, Rui et al. · 2020 · Experimental and therapeutic medicine · DOI

Full title: Puerarin promotes the viability and differentiation of MC3T3-E1 cells by enhancing LC3B-mediated autophagy through downregulation of miR-204.

Authors: Feng, Qian; Cheng, Song-Yi; Yang, Rui; Zeng, Xiang-Wei; Zhao, Feng-Ming; Zhan, Xiu-Qin

Year: 2020

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2019.8291

Paper Rapamycin regulates the balance between�cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling

Gao, Guangyuan; Chen, Weiwei; Yan, Mengjie et al. · 2019 · International Journal of Molecular Medicine · DOI

Full title: Rapamycin regulates the balance between�cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling

Authors: Gao, Guangyuan; Chen, Weiwei; Yan, Mengjie; Liu, Jinsha; Hui-ling, Luo; Wang, Chang; Yang, Ping

Year: 2019

Venue: International Journal of Molecular Medicine

DOI: https://doi.org/10.3892/ijmm.2019.4407

Paper Ginsenoside compound K promotes β-amyloid peptide clearance in primary astrocytes via autophagy enhancement.

Guo, Jinhui; Chang, Li; Zhang, Xin et al. · 2014 · Experimental and therapeutic medicine · DOI

Full title: Ginsenoside compound K promotes β-amyloid peptide clearance in primary astrocytes via autophagy enhancement.

Authors: Guo, Jinhui; Chang, Li; Zhang, Xin; Pei, Sujuan; Yu, Meishuang; Gao, Jianlian

Year: 2014

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2014.1885

Paper Enhancing spontaneous stem cell healing (Review).

Maguire, Greg; Friedman, Peter · 2014 · Biomedical reports · DOI

Full title: Enhancing spontaneous stem cell healing (Review).

Authors: Maguire, Greg; Friedman, Peter

Year: 2014

Venue: Biomedical reports

DOI: https://doi.org/10.3892/br.2014.231

Paper KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.

Tan, Zhen; Ren, Hongqiang; Liu, Yijun et al. · 2022 · Experimental and therapeutic medicine · DOI

Full title: KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.

Authors: Tan, Zhen; Ren, Hongqiang; Liu, Yijun; Yang, Hanxuan; Luo, Qian; Deng, Xuejun

Year: 2022

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2022.11673

Paper Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux.

Zhang, Xin; Lu, Haining; Xu, Xingsheng · 2025 · Biomedical reports · DOI

Full title: Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux.

Authors: Zhang, Xin; Lu, Haining; Xu, Xingsheng

Year: 2025

Venue: Biomedical reports

DOI: https://doi.org/10.3892/br.2025.2061

Paper Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway.

Wen, Jing; Zhao, Yuyan; Guo, Lei · 2016 · International journal of molecular medicine · DOI

Full title: Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway.

Authors: Wen, Jing; Zhao, Yuyan; Guo, Lei

Year: 2016

Venue: International journal of molecular medicine

DOI: https://doi.org/10.3892/ijmm.2015.2409

Paper AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction.

Li, Yi; Su, Jiajia; Sun, Wenchao et al. · 2018 · International journal of molecular medicine · DOI

Full title: AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction.

Authors: Li, Yi; Su, Jiajia; Sun, Wenchao; Cai, Lin; Deng, Zhouming

Year: 2018

Venue: International journal of molecular medicine

DOI: https://doi.org/10.3892/ijmm.2018.3498

Paper Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice.

Jia, Min; Liu, Wenxue; Zhang, Keyin et al. · 2024 · Molecular medicine reports · DOI

Full title: Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice.

Authors: Jia, Min; Liu, Wenxue; Zhang, Keyin; Wang, Zhigang; Li, Ruisha; Pan, Jun; Yang, Jianjun; Wang, Dongjin

Year: 2024

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2024.13174

Paper GSK3β signaling is involved in ultraviolet B-induced activation of autophagy in epidermal cells.

Yang, Yang; Wang, Haiping; Wang, Siying et al. · 2012 · International journal of oncology · DOI

Full title: GSK3β signaling is involved in ultraviolet B-induced activation of autophagy in epidermal cells.

Authors: Yang, Yang; Wang, Haiping; Wang, Siying; Xu, Mei; Liu, Mei; Liao, Mingjun; Frank, Jacqueline A; Adhikari, Sabal; Bower, Kimberly A; Shi, Xianglin; Ma, Cuiling; Luo, Jia

Year: 2012

Venue: International journal of oncology

DOI: https://doi.org/10.3892/ijo.2012.1620

Paper O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review).

Huang, Zhenzhen; Liu, Xin; Zhang, Ling et al. · 2025 · Molecular medicine reports · DOI

Full title: O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review).

Authors: Huang, Zhenzhen; Liu, Xin; Zhang, Ling; Lin, Yujie; Ma, Xiangli; Li, Peiwu

Year: 2025

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2025.13646

Paper Knockdown of Beclin 1 inhibits vitamin K3‑induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells.

Yang, Chuang; Han, Li-Ou · 2010 · Molecular medicine reports · DOI

Full title: Knockdown of Beclin 1 inhibits vitamin K3‑induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells.

Authors: Yang, Chuang; Han, Li-Ou

Year: 2010

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2010.347

Paper Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion.

Wang, Yubin; He, Dawei; Ni, Chengpei et al. · 2016 · Molecular medicine reports · DOI

Full title: Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion.

Authors: Wang, Yubin; He, Dawei; Ni, Chengpei; Zhou, Huiying; Wu, Shuyan; Xue, Zhimou; Zhou, Zhengyu

Year: 2016

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2016.5531

Paper Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation.

Huang, Zhengxin; Liu, Yingfeng; Huang, Xianping · 2018 · Molecular medicine reports · DOI

Full title: Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation.

Authors: Huang, Zhengxin; Liu, Yingfeng; Huang, Xianping

Year: 2018

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2018.9544

Paper Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma.

Ou, Chengshan; Liu, Hongxia; Ding, Zhenhua et al. · 2019 · Molecular medicine reports · DOI

Full title: Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma.

Authors: Ou, Chengshan; Liu, Hongxia; Ding, Zhenhua; Zhou, Liang

Year: 2019

Venue: Molecular medicine reports

DOI: https://doi.org/10.3892/mmr.2019.10734

Paper Molecular mechanisms of tamoxifen-associated endometrial cancer (Review)

Hu, Rong; Hilakivi‐Clarke, Leena; Clarke, Robert · 2015 · Oncology Letters · DOI

Full title: Molecular mechanisms of tamoxifen-associated endometrial cancer (Review)

Authors: Hu, Rong; Hilakivi‐Clarke, Leena; Clarke, Robert

Year: 2015

Venue: Oncology Letters

DOI: https://doi.org/10.3892/ol.2015.2962

Paper Rapamycin promotes the anticancer action of dihydroartemisinin in breast cancer MDA-MB-231 cells by regulating expression of Atg7 and DAPK.

Liu, Qiujun; Zhou, Xianyao; Li, Chuan et al. · 2018 · Oncology letters · DOI

Full title: Rapamycin promotes the anticancer action of dihydroartemisinin in breast cancer MDA-MB-231 cells by regulating expression of Atg7 and DAPK.

Authors: Liu, Qiujun; Zhou, Xianyao; Li, Chuan; Zhang, Xuemei; Li, Chang Long

Year: 2018

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2018.8013

Paper Neurodegenerative Diseases: Regenerative Mechanisms and Novel Therapeutic Approaches

Hussain, Rashad; Zubair, Hira; Pursell, Sarah et al. · 2018 · Brain Sciences · DOI

Full title: Neurodegenerative Diseases: Regenerative Mechanisms and Novel Therapeutic Approaches

Authors: Hussain, Rashad; Zubair, Hira; Pursell, Sarah; Shahab, Muhammad

Year: 2018

Venue: Brain Sciences

DOI: https://doi.org/10.3390/brainsci8090177

Paper Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

Peyressatre, Marion; Prével, Camille; Pellerano, Morgan et al. · 2015 · Cancers · DOI

Full title: Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

Authors: Peyressatre, Marion; Prével, Camille; Pellerano, Morgan; Morris, May C.

Year: 2015

Venue: Cancers

DOI: https://doi.org/10.3390/cancers7010179

Paper Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies

Mueller, Anna‐Lena; Payandeh, Zahra; Mohammadkhani, Niloufar et al. · 2021 · Cells · DOI

Full title: Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies

Authors: Mueller, Anna‐Lena; Payandeh, Zahra; Mohammadkhani, Niloufar; Mubarak, Shaden M. H.; Zakeri, Alireza; Bahrami, Armina Alagheband; Brockmueller, Aranka; Shakibaei, Mehdi

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10113017

Paper mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

Tian, Tian; Li, Xiaoyi; Zhang, Jinhua · 2019 · International Journal of Molecular Sciences · DOI

Full title: mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

Authors: Tian, Tian; Li, Xiaoyi; Zhang, Jinhua

Year: 2019

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms20030755

Paper Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease

Bulck, Michiel Van; Sierra‐Magro, Ana; Alarcón-Gil, Jesús et al. · 2019 · International Journal of Molecular Sciences · DOI

Full title: Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease

Authors: Bulck, Michiel Van; Sierra‐Magro, Ana; Alarcón-Gil, Jesús; Pérez‐Castillo, Ana; Morales-García, José Á.

Year: 2019

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms20030719

Paper Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia

Eshraghi, Mehdi; Adlimoghaddam, Aida; Mahmoodzadeh, Amir et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia

Authors: Eshraghi, Mehdi; Adlimoghaddam, Aida; Mahmoodzadeh, Amir; Sharifzad, Farzaneh; Yasavoli‐Sharahi, Hamed; Lorzadeh, Shahrokh; Albensi, Benedict C.; Ghavami, Saeid

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22073330

Paper Critical Roles and Molecular Mechanisms of Chaperone-Mediated Autophagy in Infections.

Wang, Min; Wu, Min · 2026 · International journal of molecular sciences · DOI

Full title: Critical Roles and Molecular Mechanisms of Chaperone-Mediated Autophagy in Infections.

Authors: Wang, Min; Wu, Min

Year: 2026

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms27031164

Paper Nanoparticles: Taking a Unique Position in Medicine

Joseph, Tomy Muringayil; Mahapatra, Debarshi Kar; Esmaeili, Amin et al. · 2023 · Nanomaterials · DOI

Full title: Nanoparticles: Taking a Unique Position in Medicine

Authors: Joseph, Tomy Muringayil; Mahapatra, Debarshi Kar; Esmaeili, Amin; Piszczyk, Łukasz; Hasanin, Mohamed S.; Kattali, Mashhoor; Haponiuk, Józef T.; Thomas, Sabu

Year: 2023

Venue: Nanomaterials

DOI: https://doi.org/10.3390/nano13030574

Paper Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

Rahman, Md. Mominur; Rahaman, Md. Saidur; Islam, Md. Rezaul et al. · 2021 · Molecules · DOI

Full title: Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

Authors: Rahman, Md. Mominur; Rahaman, Md. Saidur; Islam, Md. Rezaul; Rahman, Firoza; Mithi, Faria Mannan; Alqahtani, Taha; Almikhlafi, Mohannad A.; Alghamdi, Samia Q.; Alruwaili, Abdullah S.; Hossain, Md. Sohel; Ahmed, Muniruddin; Das, Rajib; Emran, Talha Bin; Uddin, Md. Sahab

Year: 2021

Venue: Molecules

DOI: https://doi.org/10.3390/molecules27010233

Paper Exosome-Based Drug Delivery: Translation from Bench to Clinic

Koh, Hee Byung; Kim, Hyo Jeong; Kang, Shin‐Wook et al. · 2023 · Pharmaceutics · DOI

Full title: Exosome-Based Drug Delivery: Translation from Bench to Clinic

Authors: Koh, Hee Byung; Kim, Hyo Jeong; Kang, Shin‐Wook; Yoo, Tae‐Hyun

Year: 2023

Venue: Pharmaceutics

DOI: https://doi.org/10.3390/pharmaceutics15082042

Paper Overview of Metformin and Neurodegeneration: A Comprehensive Review.

Kruczkowska, Weronika; Gałęziewska, Julia; Buczek, Paulina et al. · 2025 · Pharmaceuticals (Basel, Switzerland) · DOI

Full title: Overview of Metformin and Neurodegeneration: A Comprehensive Review.

Authors: Kruczkowska, Weronika; Gałęziewska, Julia; Buczek, Paulina; Płuciennik, Elżbieta; Kciuk, Mateusz; Śliwińska, Agnieszka

Year: 2025

Venue: Pharmaceuticals (Basel, Switzerland)

DOI: https://doi.org/10.3390/ph18040486

Paper Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation.

Gao, Junwei; Wu, Yunzhou; Cai, Xudong et al. · 2025 · Frontiers in pharmacology · DOI

Full title: Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation.

Authors: Gao, Junwei; Wu, Yunzhou; Cai, Xudong; Zhao, Hailing; Xing, Jie

Year: 2025

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2025.1665339

Paper A review on anti-cancer properties of quercetin in gastric cancer.

Xie, Xiaoxia; Wei, Yan · 2025 · Frontiers in pharmacology · DOI

Full title: A review on anti-cancer properties of quercetin in gastric cancer.

Authors: Xie, Xiaoxia; Wei, Yan

Year: 2025

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2025.1563229

Paper Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy.

Seabright, Alex P; Lai, Yu-Chiang · 2020 · Frontiers in physiology · DOI

Full title: Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy.

Authors: Seabright, Alex P; Lai, Yu-Chiang

Year: 2020

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2020.608474

Paper Pterostilbene attenuates osteoarthritis progression through p53-dependent autophagy activation: evidence from network analysis and experimental validation.

Wu, Jiangping; Zhang, Chunpan; Qin, Yuanyuan et al. · 2026 · Frontiers in pharmacology · DOI

Full title: Pterostilbene attenuates osteoarthritis progression through p53-dependent autophagy activation: evidence from network analysis and experimental validation.

Authors: Wu, Jiangping; Zhang, Chunpan; Qin, Yuanyuan; Zhu, Lixuan; Liu, Lingyan; Xu, Fei

Year: 2026

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2026.1686555

Paper Exploring bioactive phytochemicals as ULK1 activators for enhancing cytoprotective autophagy in amyotrophic lateral sclerosis.

Anjum, Farah; Hawsawi, Nahed; Almalki, Abdulraheem Ali et al. · 2025 · Frontiers in pharmacology · DOI

Full title: Exploring bioactive phytochemicals as ULK1 activators for enhancing cytoprotective autophagy in amyotrophic lateral sclerosis.

Authors: Anjum, Farah; Hawsawi, Nahed; Almalki, Abdulraheem Ali; Shamsi, Anas; Hulbah, Maram Jameel; Bakhuraysah, Maha; Alsharif, Abdulaziz; Mohammad, Taj

Year: 2025

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2025.1661744

Paper The endoplasmic reticulum stress response in aging and age-related diseases

Brown, Marishka; Naidoo, Nirinjini · 2012 · Frontiers in Physiology · DOI

Full title: The endoplasmic reticulum stress response in aging and age-related diseases

Authors: Brown, Marishka; Naidoo, Nirinjini

Year: 2012

Venue: Frontiers in Physiology

DOI: https://doi.org/10.3389/fphys.2012.00263

Paper Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.

Murphy, Kevin R; Baggett, Brett; Cooper, Leroy L et al. · 2019 · Frontiers in physiology · DOI

Full title: Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.

Authors: Murphy, Kevin R; Baggett, Brett; Cooper, Leroy L; Lu, Yichun; O-Uchi, Jin; Sedivy, John M; Terentyev, Dmitry; Koren, Gideon

Year: 2019

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2019.01277

Paper Role of AMPK in autophagy.

Wang, Shengyuan; Li, Hongyan; Yuan, Minghao et al. · 2022 · Frontiers in physiology · DOI

Full title: Role of AMPK in autophagy.

Authors: Wang, Shengyuan; Li, Hongyan; Yuan, Minghao; Fan, Haixia; Cai, Zhiyou

Year: 2022

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2022.1015500

Paper Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.

Huang, Hsuan-Ti; Cheng, Tsung-Lin; Ho, Cheng-Jung et al. · 2020 · Antioxidants (Basel, Switzerland) · DOI

Full title: Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.

Authors: Huang, Hsuan-Ti; Cheng, Tsung-Lin; Ho, Cheng-Jung; Huang, Han Hsiang; Lu, Cheng-Chang; Chuang, Shu-Chun; Li, Jhong-You; Lee, Tien-Ching; Chen, Shih-Tse; Lin, Yi-Shan; Lee, Chih-Yao; Kang, Lin; Lin, Sung-Yen; Chen, Chung-Hwan

Year: 2020

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox10010008

Paper Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.

Wang, Xinbo; Zhang, Yuming; Li, Yansong et al. · 2021 · Frontiers in veterinary science · DOI

Full title: Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.

Authors: Wang, Xinbo; Zhang, Yuming; Li, Yansong; Tang, Mingyu; Deng, Qinghua; Mao, Jingdong; Du, Liyin

Year: 2021

Venue: Frontiers in veterinary science

DOI: https://doi.org/10.3389/fvets.2021.773514

Paper Mechanisms and Therapeutic Targets of Depression After Intracerebral Hemorrhage.

Wu, Yinan; Wang, Liangliang; Hu, Kaimin et al. · 2018 · Frontiers in psychiatry · DOI

Full title: Mechanisms and Therapeutic Targets of Depression After Intracerebral Hemorrhage.

Authors: Wu, Yinan; Wang, Liangliang; Hu, Kaimin; Yu, Chengcheng; Zhu, Yuanhan; Zhang, Suzhan; Shao, Anwen

Year: 2018

Venue: Frontiers in psychiatry

DOI: https://doi.org/10.3389/fpsyt.2018.00682

Paper Arctigenin from Fructus arctii Exhibits Antiaging Effects via Autophagy Induction, Antioxidative Stress, and Increase in Telomerase Activity in Yeast.

Chen, Siqi; Li, Yajing; Wu, Enchan et al. · 2024 · Antioxidants (Basel, Switzerland) · DOI

Full title: Arctigenin from Fructus arctii Exhibits Antiaging Effects via Autophagy Induction, Antioxidative Stress, and Increase in Telomerase Activity in Yeast.

Authors: Chen, Siqi; Li, Yajing; Wu, Enchan; Li, Qing; Xiang, Lan; Qi, Jianhua

Year: 2024

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox13060684

Paper Procyanidin A1 from Peanut Skin Exerts Anti-Aging Effects and Attenuates Senescence via Antioxidative Stress and Autophagy Induction.

Li, Yajing; Xiang, Lan; Qi, Jianhua · 2025 · Antioxidants (Basel, Switzerland) · DOI

Full title: Procyanidin A1 from Peanut Skin Exerts Anti-Aging Effects and Attenuates Senescence via Antioxidative Stress and Autophagy Induction.

Authors: Li, Yajing; Xiang, Lan; Qi, Jianhua

Year: 2025

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox14030322

Paper Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration

Picca, Anna; Calvani, Riccardo; Coelho‐Júnior, Hélio José et al. · 2020 · Antioxidants · DOI

Full title: Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration

Authors: Picca, Anna; Calvani, Riccardo; Coelho‐Júnior, Hélio José; Landi, Francesco; Bernabei, Roberto; Marzetti, Emanuele

Year: 2020

Venue: Antioxidants

DOI: https://doi.org/10.3390/antiox9080647

Paper Hydrogen Sulfide (H2S) Metabolism, Iron Overload, and Apoptosis-Autophagy Equilibrium in Vascular Smooth Muscle Cells.

Arif, Hassan Mustafa; Fu, Ming; Wang, Rui · 2025 · Antioxidants (Basel, Switzerland) · DOI

Full title: Hydrogen Sulfide (H2S) Metabolism, Iron Overload, and Apoptosis-Autophagy Equilibrium in Vascular Smooth Muscle Cells.

Authors: Arif, Hassan Mustafa; Fu, Ming; Wang, Rui

Year: 2025

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox14050560

Paper Using Zebrafish to Dissect the Interaction of Mycobacteria with the Autophagic Machinery in Macrophages.

Muñoz-Sánchez, Salomé; Varela, Mónica; van der Vaart, Michiel et al. · 2023 · Biology · DOI

Full title: Using Zebrafish to Dissect the Interaction of Mycobacteria with the Autophagic Machinery in Macrophages.

Authors: Muñoz-Sánchez, Salomé; Varela, Mónica; van der Vaart, Michiel; Meijer, Annemarie H

Year: 2023

Venue: Biology

DOI: https://doi.org/10.3390/biology12060817

Paper Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines.

Ohnishi, Kohta; Yano, Satoshi; Fujimoto, Moe et al. · 2020 · Antioxidants (Basel, Switzerland) · DOI

Full title: Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines.

Authors: Ohnishi, Kohta; Yano, Satoshi; Fujimoto, Moe; Sakai, Maiko; Harumoto, Erika; Furuichi, Airi; Masuda, Masashi; Ohminami, Hirokazu; Yamanaka-Okumura, Hisami; Hara, Taichi; Taketani, Yutaka

Year: 2020

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox9121193

Paper Role of TFEB in Huntington's Disease.

Ojalvo-Pacheco, Javier; Yakhine-Diop, Sokhna M S; Fuentes, José M et al. · 2024 · Biology · DOI

Full title: Role of TFEB in Huntington's Disease.

Authors: Ojalvo-Pacheco, Javier; Yakhine-Diop, Sokhna M S; Fuentes, José M; Paredes-Barquero, Marta; Niso-Santano, Mireia

Year: 2024

Venue: Biology

DOI: https://doi.org/10.3390/biology13040238

Paper Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases.

Huang, Fu-Chen · 2024 · Biomedicines · DOI

Full title: Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases.

Authors: Huang, Fu-Chen

Year: 2024

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines12122912

Paper The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect.

He, Jing; He, Min; Sun, Mengmeng et al. · 2025 · Biomolecules · DOI

Full title: The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect.

Authors: He, Jing; He, Min; Sun, Mengmeng; Chen, Hongxiu; Dou, Zhiqiang; Nie, Ru; Zhou, Jun; Tang, Qingqing; Che, Cong; Liu, Jie; Li, Tie

Year: 2025

Venue: Biomolecules

DOI: https://doi.org/10.3390/biom15020263

Paper Mesenchymal Stem Cell-Derived Exosomes miR-143-3p Attenuates Diabetic Kidney Disease by Enhancing Podocyte Autophagy via Bcl-2/Beclin1 Pathway.

Song, Wenze; Wang, Jiao; Guan, Lulu et al. · 2026 · Biomedicines · DOI

Full title: Mesenchymal Stem Cell-Derived Exosomes miR-143-3p Attenuates Diabetic Kidney Disease by Enhancing Podocyte Autophagy via Bcl-2/Beclin1 Pathway.

Authors: Song, Wenze; Wang, Jiao; Guan, Lulu; Zou, Yun; Liu, Jiarong; Chen, Wen; Xu, Jixiong; Cai, Wei

Year: 2026

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines14010184

Paper Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy.

Alshaman, Reem; Kolieb, Eman; El-Sayed, Rehab M et al. · 2024 · Biomedicines · DOI

Full title: Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy.

Authors: Alshaman, Reem; Kolieb, Eman; El-Sayed, Rehab M; Gouda, Sahar Galal; Alattar, Abdullah; Zaitone, Sawsan A; Abdelmaogood, Asmaa K K; Elabbasy, Lamiaa M; Eltrawy, Amira H; Sayd, Fai Yahya; Mokhtar, Hatem I; Wafa, Esam Ghanem Abu El; Ahmed, Esam Sayed; Liang, Dong; Ali, Dina A

Year: 2024

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines12030552

Paper Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lisosan G.

Bongiorni, Silvia; Catalani, Elisabetta; Arisi, Ivan et al. · 2024 · Biomolecules · DOI

Full title: Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lisosan G.

Authors: Bongiorni, Silvia; Catalani, Elisabetta; Arisi, Ivan; Lazzarini, Francesca; Del Quondam, Simona; Brunetti, Kashi; Cervia, Davide; Prantera, Giorgio

Year: 2024

Venue: Biomolecules

DOI: https://doi.org/10.3390/biom14070855

Paper Endogenous Mechanisms of Neuroprotection: To Boost or Not to Boost.

Marmolejo-Martínez-Artesero, Sara; Casas, Caty; Romeo-Guitart, David · 2021 · Cells · DOI

Full title: Endogenous Mechanisms of Neuroprotection: To Boost or Not to Boost.

Authors: Marmolejo-Martínez-Artesero, Sara; Casas, Caty; Romeo-Guitart, David

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10020370

Paper Reversal of Myofibroblast Apoptosis Resistance and Collagen Deposition by Phaseoloidin-Induced Autophagy Attenuates Pulmonary Fibrosis.

Li, Siyuan; Qian, Jiazhen; Deng, Lang et al. · 2025 · Biomedicines · DOI

Full title: Reversal of Myofibroblast Apoptosis Resistance and Collagen Deposition by Phaseoloidin-Induced Autophagy Attenuates Pulmonary Fibrosis.

Authors: Li, Siyuan; Qian, Jiazhen; Deng, Lang; Liu, Wei; Tang, Siyuan; Xie, Weixi

Year: 2025

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines13112679

Paper Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse.

Thongchot, Suyanee; Vidoni, Chiara; Ferraresi, Alessandra et al. · 2021 · Cancers · DOI

Full title: Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse.

Authors: Thongchot, Suyanee; Vidoni, Chiara; Ferraresi, Alessandra; Loilome, Watcharin; Khuntikeo, Narong; Sangkhamanon, Sakkarn; Titapun, Attapol; Isidoro, Ciro; Namwat, Nisana

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13092134

Paper Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

Bianchi, Nicoletta; Ancona, Pietro; Aguiari, Gianluca · 2025 · Cancers · DOI

Full title: Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

Authors: Bianchi, Nicoletta; Ancona, Pietro; Aguiari, Gianluca

Year: 2025

Venue: Cancers

DOI: https://doi.org/10.3390/cancers17101613

Paper BECLIN1: Protein Structure, Function and Regulation

Tran, Sharon; Fairlie, W. Douglas; Lee, Erinna F. · 2021 · Cells · DOI

Full title: BECLIN1: Protein Structure, Function and Regulation

Authors: Tran, Sharon; Fairlie, W. Douglas; Lee, Erinna F.

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10061522

Paper Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.

Guo, Qing; Wang, Bing; Wang, Xiaobo et al. · 2021 · Cells · DOI

Full title: Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.

Authors: Guo, Qing; Wang, Bing; Wang, Xiaobo; Smith, Wanli W; Zhu, Yi; Liu, Zhaohui

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10081850

Paper Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System.

Kanno, Haruo; Handa, Kyoichi; Murakami, Taishi et al. · 2022 · Cells · DOI

Full title: Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System.

Authors: Kanno, Haruo; Handa, Kyoichi; Murakami, Taishi; Aizawa, Toshimi; Ozawa, Hiroshi

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11071205

Paper Calcium Signaling Regulates Autophagy and Apoptosis

Sukumaran, Pramod; Conceicao, Viviane Nascimento Da; Sun, Yuyang et al. · 2021 · Cells · DOI

Full title: Calcium Signaling Regulates Autophagy and Apoptosis

Authors: Sukumaran, Pramod; Conceicao, Viviane Nascimento Da; Sun, Yuyang; Ahamad, Naseem; Saraiva, Luís R.; Selvaraj, Senthil; Singh, Brij B.

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10082125

Paper 14-3-3 Proteins are Regulators of Autophagy.

Pozuelo-Rubio, Mercedes · 2012 · Cells · DOI

Full title: 14-3-3 Proteins are Regulators of Autophagy.

Authors: Pozuelo-Rubio, Mercedes

Year: 2012

Venue: Cells

DOI: https://doi.org/10.3390/cells1040754

Paper Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

Decuypere, Jean-Paul; Parys, Jan B.; Bultynck, Geert · 2012 · Cells · DOI

Full title: Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

Authors: Decuypere, Jean-Paul; Parys, Jan B.; Bultynck, Geert

Year: 2012

Venue: Cells

DOI: https://doi.org/10.3390/cells1030284

Paper Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation.

Ryter, Stefan W · 2021 · Cells · DOI

Full title: Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation.

Authors: Ryter, Stefan W

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10030515

Paper The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.

Liao, Zhaozhong; Gong, Zunshuang; Wang, Zhe et al. · 2022 · Cells · DOI

Full title: The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.

Authors: Liao, Zhaozhong; Gong, Zunshuang; Wang, Zhe; Yang, Weiyan; Liu, Wenjing; Hou, Lin; Liu, Xiaokun; Hua, Junnan; Wang, Bin; Li, Ning

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11172706

Paper GBA Variants and Parkinson Disease: Mechanisms and Treatments

Smith, Laura; Schapira, Anthony H.V. · 2022 · Cells · DOI

Full title: GBA Variants and Parkinson Disease: Mechanisms and Treatments

Authors: Smith, Laura; Schapira, Anthony H.V.

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11081261

Paper Immunohistochemistry of programmed cell death in archival human pathology specimens.

Hasui, Kazuhisa; Nagai, Taku; Wang, Jia et al. · 2012 · Cells · DOI

Full title: Immunohistochemistry of programmed cell death in archival human pathology specimens.

Authors: Hasui, Kazuhisa; Nagai, Taku; Wang, Jia; Jia, Xinshan; Aozasa, Katsuyuki; Izumo, Shuji; Kawano, Yoshifumi; Kanekura, Takuro; Eizuru, Yoshito; Matsuyama, Takami

Year: 2012

Venue: Cells

DOI: https://doi.org/10.3390/cells1020074

Paper CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.

Zhang, Cheng; Deng, Yian; Zhang, Yingsi et al. · 2023 · Cells · DOI

Full title: CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.

Authors: Zhang, Cheng; Deng, Yian; Zhang, Yingsi; Ba, Tongtong; Niu, Sai; Chen, Yiqin; Gao, Yuan; Dai, Hanchuan

Year: 2023

Venue: Cells

DOI: https://doi.org/10.3390/cells12010182

Paper Structural and Functional Perspectives of Optineurin in Autophagy, Immune Signaling, and Cancer.

Medigovic, Gianluca; Rachamala, Hari Krishnareddy; Dutta, Shamit Kumar et al. · 2025 · Cells · DOI

Full title: Structural and Functional Perspectives of Optineurin in Autophagy, Immune Signaling, and Cancer.

Authors: Medigovic, Gianluca; Rachamala, Hari Krishnareddy; Dutta, Shamit Kumar; Pal, Krishnendu

Year: 2025

Venue: Cells

DOI: https://doi.org/10.3390/cells14221746

Paper PLEKHM1 Overexpression Impairs Autophagy and Exacerbates Neurodegeneration in rAAV-α-Synuclein Mice.

Höfs, Lennart; Geißler-Lösch, David; Falkenburger, Björn H · 2025 · Cells · DOI

Full title: PLEKHM1 Overexpression Impairs Autophagy and Exacerbates Neurodegeneration in rAAV-α-Synuclein Mice.

Authors: Höfs, Lennart; Geißler-Lösch, David; Falkenburger, Björn H

Year: 2025

Venue: Cells

DOI: https://doi.org/10.3390/cells14171340

Paper From Orange to Oncology: Anti-Inflammatory and Anti-Cancer Mechanisms of Sinensetin

Dong Joon Kim; Songyeon Ahn; Xiaomeng Xie et al. · 2026 · Cells · DOI

Full title: From Orange to Oncology: Anti-Inflammatory and Anti-Cancer Mechanisms of Sinensetin

Authors: Dong Joon Kim; Songyeon Ahn; Xiaomeng Xie; Yeon-Sun Seong; Yong Weon Yi

Year: 2026

Venue: Cells

DOI: https://doi.org/10.3390/cells15020110

Paper Mitophagy in Parkinson’s Disease: From Pathogenesis to Treatment

Liu, Jia; Liu, Weijin; Li, Ruolin et al. · 2019 · Cells · DOI

Full title: Mitophagy in Parkinson’s Disease: From Pathogenesis to Treatment

Authors: Liu, Jia; Liu, Weijin; Li, Ruolin; Yang, Hui

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8070712

Paper Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

Ebrahim, Nesrine; Ahmed, Inas A.; Hussien, Noha I. et al. · 2018 · Cells · DOI

Full title: Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

Authors: Ebrahim, Nesrine; Ahmed, Inas A.; Hussien, Noha I.; Dessouky, Arigue A.; Farid, Ayman; ElShazly, Amal A.A.; Mostafa, Ola; Gazzar, Walaa Bayoumie El; Sorour, Safwa M.; Seleem, Yasmin; Hussein, Ahmed; Sabry, Dina

Year: 2018

Venue: Cells

DOI: https://doi.org/10.3390/cells7120226

Paper Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases

Harrell, Carl Randall; Jovičić, Nemanja; Djonov, Valentin et al. · 2019 · Cells · DOI

Full title: Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases

Authors: Harrell, Carl Randall; Jovičić, Nemanja; Djonov, Valentin; Arsenijević, Nebojša; Volarević, Vladislav

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8121605

Paper Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives

Kusaczuk, Magdalena · 2019 · Cells · DOI

Full title: Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives

Authors: Kusaczuk, Magdalena

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8121471

Paper The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer

Yang, Hung‐Chi; Wu, Yi‐Hsuan; Yen, Wei‐Chen et al. · 2019 · Cells · DOI

Full title: The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer

Authors: Yang, Hung‐Chi; Wu, Yi‐Hsuan; Yen, Wei‐Chen; Liu, Hui-Ya; Hwang, Tsong‐Long; Stern, Arnold; Chiu, Daniel T.

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8091055

Paper Autophagy in Chronic Kidney Diseases

Lin, Tien‐An; Wu, Victor Chien‐Chia; Wang, Chao‐Yung · 2019 · Cells · DOI

Full title: Autophagy in Chronic Kidney Diseases

Authors: Lin, Tien‐An; Wu, Victor Chien‐Chia; Wang, Chao‐Yung

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8010061

Paper Melatonin Regulates Aging and Neurodegeneration through Energy Metabolism, Epigenetics, Autophagy and Circadian Rhythm Pathways

Jenwitheesuk, Anorut; Nopparat, Chutikorn; Mukda, Sujira et al. · 2014 · International Journal of Molecular Sciences · DOI

Full title: Melatonin Regulates Aging and Neurodegeneration through Energy Metabolism, Epigenetics, Autophagy and Circadian Rhythm Pathways

Authors: Jenwitheesuk, Anorut; Nopparat, Chutikorn; Mukda, Sujira; Wongchitrat, Prapimpun; Govitrapong, Piyarat

Year: 2014

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms150916848

Paper The Mitochondrial Basis of Aging and Age-Related Disorders

Srivastava, Sarika · 2017 · Genes · DOI

Full title: The Mitochondrial Basis of Aging and Age-Related Disorders

Authors: Srivastava, Sarika

Year: 2017

Venue: Genes

DOI: https://doi.org/10.3390/genes8120398

Paper Ghrelin in Focus: Dissecting Its Critical Roles in Gastrointestinal Pathologies and Therapies.

Wu, Wei; Zhu, Lei; Dou, Zhimin et al. · 2024 · Current issues in molecular biology · DOI

Full title: Ghrelin in Focus: Dissecting Its Critical Roles in Gastrointestinal Pathologies and Therapies.

Authors: Wu, Wei; Zhu, Lei; Dou, Zhimin; Hou, Qiliang; Wang, Sen; Yuan, Ziqian; Li, Bin

Year: 2024

Venue: Current issues in molecular biology

DOI: https://doi.org/10.3390/cimb46010061

Paper TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy.

Kang, Hyun Je; Yoo, Eun Jin; Lee, Hwan Hee et al. · 2020 · Cells · DOI

Full title: TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy.

Authors: Kang, Hyun Je; Yoo, Eun Jin; Lee, Hwan Hee; An, Seung Min; Park, Hyun; Lee-Kwon, Whaseon; Choi, Soo Youn; Kwon, Hyug Moo

Year: 2020

Venue: Cells

DOI: https://doi.org/10.3390/cells9091928

Paper Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach

Chen, Lian; Cui, Hengmin · 2015 · International Journal of Molecular Sciences · DOI

Full title: Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach

Authors: Chen, Lian; Cui, Hengmin

Year: 2015

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms160922830

Paper Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

Plaza‐Zabala, Ainhoa; Sierra‐Torre, Virginia; Sierra, Amanda · 2017 · International Journal of Molecular Sciences · DOI

Full title: Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

Authors: Plaza‐Zabala, Ainhoa; Sierra‐Torre, Virginia; Sierra, Amanda

Year: 2017

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms18030598

Paper Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

Campanella, Claudia; Pace, Andrea; Bavisotto, Celeste Caruso et al. · 2018 · International Journal of Molecular Sciences · DOI

Full title: Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

Authors: Campanella, Claudia; Pace, Andrea; Bavisotto, Celeste Caruso; Marzullo, Paola; Marino, Antonella; Buscemi, Silvestre; Piccionello, Antonio Palumbo

Year: 2018

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms19092603

Paper Bioactivities of Phenolics by Focusing on Suppression of Chronic Diseases: A Review

Shahidi, Fereidoon; Yeo, JuDong · 2018 · International Journal of Molecular Sciences · DOI

Full title: Bioactivities of Phenolics by Focusing on Suppression of Chronic Diseases: A Review

Authors: Shahidi, Fereidoon; Yeo, JuDong

Year: 2018

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms19061573

Paper Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates

Park, Hyungsun; Kang, Ju‐Hee; Lee, Seongju · 2020 · International Journal of Molecular Sciences · DOI

Full title: Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates

Authors: Park, Hyungsun; Kang, Ju‐Hee; Lee, Seongju

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21093369

Paper Activate or Inhibit? Implications of Autophagy Modulation as a Therapeutic Strategy for Alzheimer's Disease.

Krishnan, Sharmeelavathi; Shrestha, Yasaswi; Jayatunga, Dona P W et al. · 2020 · International journal of molecular sciences · DOI

Full title: Activate or Inhibit? Implications of Autophagy Modulation as a Therapeutic Strategy for Alzheimer's Disease.

Authors: Krishnan, Sharmeelavathi; Shrestha, Yasaswi; Jayatunga, Dona P W; Rea, Sarah; Martins, Ralph; Bharadwaj, Prashant

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21186739

Paper The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease

Badanjak, Katja; Fixemer, Sonja; Smajić, Semra et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease

Authors: Badanjak, Katja; Fixemer, Sonja; Smajić, Semra; Skupin, Alexander; Grünewald, Anne

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22094676

Paper Targeting AKT/mTOR in Oral Cancer: Mechanisms and Advances in Clinical Trials

Harsha, Choudhary; Banik, Kishore; Ang, Hui Li et al. · 2020 · International Journal of Molecular Sciences · DOI

Full title: Targeting AKT/mTOR in Oral Cancer: Mechanisms and Advances in Clinical Trials

Authors: Harsha, Choudhary; Banik, Kishore; Ang, Hui Li; Girisa, Sosmitha; Vikkurthi, Rajesh; Dey, Parama; Rana, Varsha; Shabnam, Bano; Khatoon, Elina; Kumar, Alan Prem; Kunnumakkara, Ajaikumar B.

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21093285

Paper Autophagy and neurodegeneration

Frake, Rebecca A.; Ricketts, Thomas C.; Menzies, Fiona M. et al. · 2015 · Journal of Clinical Investigation · DOI

Full title: Autophagy and neurodegeneration

Authors: Frake, Rebecca A.; Ricketts, Thomas C.; Menzies, Fiona M.; Rubinsztein, David C.

Year: 2015

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci73944

Paper Development of autophagy inducers in clinical medicine.

Levine, Beth; Packer, Milton; Codogno, Patrice · 2015 · The Journal of clinical investigation · DOI

Full title: Development of autophagy inducers in clinical medicine.

Authors: Levine, Beth; Packer, Milton; Codogno, Patrice

Year: 2015

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI73938

Paper Pharmacologic agents targeting autophagy

Vakifahmetoglu-Norberg, Helin; Xia, Hongguang; Yuan, Junying · 2015 · Journal of Clinical Investigation · DOI

Full title: Pharmacologic agents targeting autophagy

Authors: Vakifahmetoglu-Norberg, Helin; Xia, Hongguang; Yuan, Junying

Year: 2015

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci73937

Paper The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP.

Stone, Sarrabeth; Wu, Shuangchan; Nave, Klaus-Armin et al. · 2020 · JCI insight · DOI

Full title: The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP.

Authors: Stone, Sarrabeth; Wu, Shuangchan; Nave, Klaus-Armin; Lin, Wensheng

Year: 2020

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.132364

Paper Emerging mechanisms of molecular pathology in ALS

Peters, Owen M.; Ghasemi, Mehdi; Brown, Robert H. · 2015 · Journal of Clinical Investigation · DOI

Full title: Emerging mechanisms of molecular pathology in ALS

Authors: Peters, Owen M.; Ghasemi, Mehdi; Brown, Robert H.

Year: 2015

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci71601

Paper HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury.

Huang, Yichen; Meng, Shan; Wu, Biwu et al. · 2023 · JCI insight · DOI

Full title: HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury.

Authors: Huang, Yichen; Meng, Shan; Wu, Biwu; Shi, Hong; Wang, Yana; Xiang, Jiakun; Li, Jiaying; Shi, Ziyu; Wu, Gang; Lyu, Yanchen; Jia, Xu; Hu, Jin; Xu, Zhi-Xiang; Gao, Yanqin

Year: 2023

Venue: JCI insight

DOI: https://doi.org/10.1172/jci.insight.168919

Paper Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?

Gupta, Dhananjay; Leahy, Jack L · 2014 · The Journal of clinical investigation · DOI

Full title: Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?

Authors: Gupta, Dhananjay; Leahy, Jack L

Year: 2014

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI77506

Paper Signaling pathway cross talk in Alzheimer’s disease

Godoy, Juan A.; Ríos, Juvenal A.; Zolezzi, Juan M. et al. · 2014 · Cell Communication and Signaling · DOI

Full title: Signaling pathway cross talk in Alzheimer’s disease

Authors: Godoy, Juan A.; Ríos, Juvenal A.; Zolezzi, Juan M.; Braidy, Nady; Inestrosa, Nibaldo C.

Year: 2014

Venue: Cell Communication and Signaling

DOI: https://doi.org/10.1186/1478-811x-12-23

Paper Role of the ubiquitin proteasome system in Alzheimer's disease

Upadhya, Sudarshan C.; Hegde, Ashok N. · 2007 · BMC Biochemistry · DOI

Full title: Role of the ubiquitin proteasome system in Alzheimer's disease

Authors: Upadhya, Sudarshan C.; Hegde, Ashok N.

Year: 2007

Venue: BMC Biochemistry

DOI: https://doi.org/10.1186/1471-2091-8-s1-s12

Paper Rapamycin increases survival in ALS mice lacking mature lymphocytes.

Staats, Kim A; Hernandez, Sara; Schönefeldt, Susann et al. · 2013 · Molecular neurodegeneration · DOI

Full title: Rapamycin increases survival in ALS mice lacking mature lymphocytes.

Authors: Staats, Kim A; Hernandez, Sara; Schönefeldt, Susann; Bento-Abreu, André; Dooley, James; Van Damme, Philip; Liston, Adrian; Robberecht, Wim; Van Den Bosch, Ludo

Year: 2013

Venue: Molecular neurodegeneration

DOI: https://doi.org/10.1186/1750-1326-8-31

Paper Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

Stern, Stęphan T.; Adiseshaiah, Pavan P.; Crist, Rachael M. · 2012 · Particle and Fibre Toxicology · DOI

Full title: Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

Authors: Stern, Stęphan T.; Adiseshaiah, Pavan P.; Crist, Rachael M.

Year: 2012

Venue: Particle and Fibre Toxicology

DOI: https://doi.org/10.1186/1743-8977-9-20

Paper Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Li, Xinyuan; Fang, Pu; Mai, Jietang et al. · 2013 · Journal of Hematology & Oncology · DOI

Full title: Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Authors: Li, Xinyuan; Fang, Pu; Mai, Jietang; Choi, Eric T.; Wang, Luqiao; Yang, Xiaofeng

Year: 2013

Venue: Journal of Hematology & Oncology

DOI: https://doi.org/10.1186/1756-8722-6-19

Paper Mitochondrial oxidative stress in aging and healthspan

Dai, Dao‐Fu; Chiao, Ying Ann; Marcinek, David J. et al. · 2014 · Longevity & Healthspan · DOI

Full title: Mitochondrial oxidative stress in aging and healthspan

Authors: Dai, Dao‐Fu; Chiao, Ying Ann; Marcinek, David J.; Szeto, Hazel H.; Rabinovitch, Peter S.

Year: 2014

Venue: Longevity & Healthspan

DOI: https://doi.org/10.1186/2046-2395-3-6

Paper Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement.

Hou, Lingling; Xiong, Nian; Liu, Ling et al. · 2015 · BMC neuroscience · DOI

Full title: Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement.

Authors: Hou, Lingling; Xiong, Nian; Liu, Ling; Huang, Jinsha; Han, Chao; Zhang, Guoxin; Li, Jie; Xu, Xiaoyun; Lin, Zhicheng; Wang, Tao

Year: 2015

Venue: BMC neuroscience

DOI: https://doi.org/10.1186/s12868-015-0222-y

Paper Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy.

You, Lijiao; Zhang, Di; Geng, Huan et al. · 2021 · BMC complementary medicine and therapies · DOI

Full title: Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy.

Authors: You, Lijiao; Zhang, Di; Geng, Huan; Sun, Fangyuan; Lei, Ming

Year: 2021

Venue: BMC complementary medicine and therapies

DOI: https://doi.org/10.1186/s12906-021-03307-0

Paper Elevated VAMP8 expression promotes cervical cancer progression by enhancing autophagy via HIF-1 pathway.

Wang, Yue; Wu, Dan; Gai, Jinxia et al. · 2025 · BMC medicine · DOI

Full title: Elevated VAMP8 expression promotes cervical cancer progression by enhancing autophagy via HIF-1 pathway.

Authors: Wang, Yue; Wu, Dan; Gai, Jinxia; Cai, Yiying; Hua, Keqin; Zhu, Zhiling; Xin, Weijuan

Year: 2025

Venue: BMC medicine

DOI: https://doi.org/10.1186/s12916-025-04378-3

Paper The role of the LRRK2 gene in Parkinsonism

Li, Jieqiong; Tan, Lan; Yu, Jin‐Tai · 2014 · Molecular Neurodegeneration · DOI

Full title: The role of the LRRK2 gene in Parkinsonism

Authors: Li, Jieqiong; Tan, Lan; Yu, Jin‐Tai

Year: 2014

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/1750-1326-9-47

Paper Long non-coding RNA LINC00470 in serum derived exosome: a critical regulator for proliferation and autophagy in glioma cells.

Ma, Wenjia; Zhou, Yu; Liu, Min et al. · 2021 · Cancer cell international · DOI

Full title: Long non-coding RNA LINC00470 in serum derived exosome: a critical regulator for proliferation and autophagy in glioma cells.

Authors: Ma, Wenjia; Zhou, Yu; Liu, Min; Qin, Qilin; Cui, Yan

Year: 2021

Venue: Cancer cell international

DOI: https://doi.org/10.1186/s12935-021-01825-y

Paper Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Jing, Xinming; Yang, Fengming; Shao, Chuchu et al. · 2019 · Molecular Cancer · DOI

Full title: Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Authors: Jing, Xinming; Yang, Fengming; Shao, Chuchu; Wei, Ke; Xie, Mengyan; Shen, Hua; Shu, Yongqian

Year: 2019

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-019-1089-9

Paper CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.

Zhao, Shuo; Sun, Jiajia; Chang, Qinzheng et al. · 2024 · Cancer cell international · DOI

Full title: CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.

Authors: Zhao, Shuo; Sun, Jiajia; Chang, Qinzheng; Pang, Shuo; Zhang, Nianzhao; Fan, Yidong; Liu, Jikai

Year: 2024

Venue: Cancer cell international

DOI: https://doi.org/10.1186/s12935-024-03502-2

Paper Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p/TRAF6 axis

Tong, Hua; Yang, Mei; Song, Honghao et al. · 2022 · Journal of Nanobiotechnology · DOI

Full title: Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p/TRAF6 axis

Authors: Tong, Hua; Yang, Mei; Song, Honghao; Kong, Erliang; Deng, Mengqiu; Li, Yongchang; Li, Jian; Liu, Zhixiao; Fu, Hailong; Wang, Yue; Yuan, Hongbin

Year: 2022

Venue: Journal of Nanobiotechnology

DOI: https://doi.org/10.1186/s12951-022-01522-6

Paper Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.

Zhou, Cefan; Wang, Ming; Yang, Jing et al. · 2019 · Cell communication and signaling : CCS · DOI

Full title: Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.

Authors: Zhou, Cefan; Wang, Ming; Yang, Jing; Xiong, Hui; Wang, Yefu; Tang, Jingfeng

Year: 2019

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-019-0422-7

Paper Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.

Wang, Yixuan; Li, Feifei; Mao, Linshuang et al. · 2024 · Journal of nanobiotechnology · DOI

Full title: Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.

Authors: Wang, Yixuan; Li, Feifei; Mao, Linshuang; Liu, Yu; Chen, Shuai; Liu, Jingmeng; Huang, Ke; Chen, Qiujing; Wu, Jianrong; Lu, Lin; Zheng, Yuanyi; Shen, Weifeng; Ying, Tao; Dai, Yang; Shen, Ying

Year: 2024

Venue: Journal of nanobiotechnology

DOI: https://doi.org/10.1186/s12951-024-02357-z

Paper Ceria-Zirconia nanoparticles reduce intracellular globotriaosylceramide accumulation and attenuate kidney injury by enhancing the autophagy flux in cellular and animal models of Fabry disease.

An, Jong Hun; Hong, Sang-Eun; Yu, Seong-Lan et al. · 2022 · Journal of nanobiotechnology · DOI

Full title: Ceria-Zirconia nanoparticles reduce intracellular globotriaosylceramide accumulation and attenuate kidney injury by enhancing the autophagy flux in cellular and animal models of Fabry disease.

Authors: An, Jong Hun; Hong, Sang-Eun; Yu, Seong-Lan; Kang, Jaeku; Park, Chang Gyo; Lee, Hoi Young; Lee, Sung-Ki; Lee, Dong Chul; Park, Hwan-Woo; Hwang, Won-Min; Yun, Sung-Ro; Park, Yohan; Park, Moon Hyang; Yoon, Kuk Ro; Yoon, Se-Hee

Year: 2022

Venue: Journal of nanobiotechnology

DOI: https://doi.org/10.1186/s12951-022-01318-8

Paper Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells.

Yu, Hao; Teng, Yun; Ge, Jun et al. · 2023 · Journal of nanobiotechnology · DOI

Full title: Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells.

Authors: Yu, Hao; Teng, Yun; Ge, Jun; Yang, Ming; Xie, Haifeng; Wu, Tianyi; Yan, Qi; Jia, Mengting; Zhu, Qing; Shen, Yanping; Zhang, Lianxue; Zou, Jun

Year: 2023

Venue: Journal of nanobiotechnology

DOI: https://doi.org/10.1186/s12951-023-01856-9

Paper Nanomaterial-mediated host directed therapy of tuberculosis by manipulating macrophage autophagy.

Liu, Yilin; Wang, Jiajun; Yang, Jiayi et al. · 2024 · Journal of nanobiotechnology · DOI

Full title: Nanomaterial-mediated host directed therapy of tuberculosis by manipulating macrophage autophagy.

Authors: Liu, Yilin; Wang, Jiajun; Yang, Jiayi; Xia, Jiaojiao; Yu, Jiaqi; Chen, Dongsheng; Huang, Yuhe; Yang, Fen; Ruan, Yongdui; Xu, Jun-Fa; Pi, Jiang

Year: 2024

Venue: Journal of nanobiotechnology

DOI: https://doi.org/10.1186/s12951-024-02875-w

Paper HAS-CIRCpedia-5280 sponges miR-4712-5p inhibited colon cancer autophagyinduced by human beta-defensin-1.

An, Shixiang; Cui, Jiaxian; Yang, Wenhong et al. · 2025 · Journal of translational medicine · DOI

Full title: HAS-CIRCpedia-5280 sponges miR-4712-5p inhibited colon cancer autophagyinduced by human beta-defensin-1.

Authors: An, Shixiang; Cui, Jiaxian; Yang, Wenhong; Zhang, Mingyu; Yu, Huiling; Lu, Jingkun; Tian, Yunpeng; Qiao, Lu; Wang, Xiumei; Bao, Lili; Zhao, Pengwei

Year: 2025

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-024-05860-x

Paper The exosome journey: from biogenesis to uptake and intracellular signalling

Gurung, Sonam; Perocheau, Dany; Touramanidou, Loukia et al. · 2021 · Cell Communication and Signaling · DOI

Full title: The exosome journey: from biogenesis to uptake and intracellular signalling

Authors: Gurung, Sonam; Perocheau, Dany; Touramanidou, Loukia; Baruteau, Julien

Year: 2021

Venue: Cell Communication and Signaling

DOI: https://doi.org/10.1186/s12964-021-00730-1

Paper Loss of ADAM15 prevents necroptosis induction by partial RIPK1 degradation due to enhanced TNF-R1 surface expression and basal caspase-8 activation

S. Braun; K. Knackfuß; T. Ziesmann et al. · 2025 · Cell Communication and Signaling · DOI

Full title: Loss of ADAM15 prevents necroptosis induction by partial RIPK1 degradation due to enhanced TNF-R1 surface expression and basal caspase-8 activation

Authors: S. Braun; K. Knackfuß; T. Ziesmann; L. Mlinzk; A. Goerg; J. Frankenheim; A. Walter; W. Schneider-Brachert; U. Distler; J. Fritsch

Year: 2025

Venue: Cell Communication and Signaling

DOI: https://doi.org/10.1186/s12964-025-02530-3

Paper Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy.

Zhang, Lei; Ding, Wen-Yuan; Wang, Zhi-Hao et al. · 2016 · Journal of translational medicine · DOI

Full title: Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy.

Authors: Zhang, Lei; Ding, Wen-Yuan; Wang, Zhi-Hao; Tang, Meng-Xiong; Wang, Feng; Li, Ya; Zhong, Ming; Zhang, Yun; Zhang, Wei

Year: 2016

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-016-0849-1

Paper Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma.

Feng, Yanchun; Jiang, Yingming; Liu, Jun et al. · 2023 · Journal of translational medicine · DOI

Full title: Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma.

Authors: Feng, Yanchun; Jiang, Yingming; Liu, Jun; Liu, Jiaqi; Shi, Mengchen; Chen, Junxiong; Zhang, Jingdan; Tian, Yu; Yang, Xiangling; Liu, Huanliang

Year: 2023

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-023-04574-w

Paper Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway

Xu, Xin; Gao, Weiwei; Li, Lei et al. · 2021 · Journal of Neuroinflammation · DOI

Full title: Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway

Authors: Xu, Xin; Gao, Weiwei; Li, Lei; Hao, Jiheng; Yang, Bin; Wang, Tao; Li, Long; Bai, Xuesong; Li, Fanjian; Ren, Honglei; Zhang, Meng; Zhang, Liyong; Wang, Jiyue; Wang, Dong; Zhang, Jianning; Jiao, Liqun

Year: 2021

Venue: Journal of Neuroinflammation

DOI: https://doi.org/10.1186/s12974-021-02174-3

Paper Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1.

Chen, Xiangrong; Pan, Zhigang; Fang, Zhongning et al. · 2018 · Journal of neuroinflammation · DOI

Full title: Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1.

Authors: Chen, Xiangrong; Pan, Zhigang; Fang, Zhongning; Lin, Weibin; Wu, Shukai; Yang, Fuxing; Li, Yasong; Fu, Huangde; Gao, Hongzhi; Li, Shun

Year: 2018

Venue: Journal of neuroinflammation

DOI: https://doi.org/10.1186/s12974-018-1345-8

Paper TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated lipophagy.

Ma, Wenliang; Chen, Yi; Chen, Guijuan et al. · 2025 · Cell communication and signaling : CCS · DOI

Full title: TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated lipophagy.

Authors: Ma, Wenliang; Chen, Yi; Chen, Guijuan; Yang, Lei; Lu, Yanwen; Dong, Xiang; Li, Dongmei; Gan, Weidong

Year: 2025

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-025-02117-y

Paper Transcranial direct current stimulation exerts neuroprotective effects in Parkinson's disease by restoring Mlst8-mediated autophagic homeostasis.

Tian, Zekun; Long, Chao; Wei, Juan et al. · 2026 · Journal of translational medicine · DOI

Full title: Transcranial direct current stimulation exerts neuroprotective effects in Parkinson's disease by restoring Mlst8-mediated autophagic homeostasis.

Authors: Tian, Zekun; Long, Chao; Wei, Juan; Jiang, Yan; Liu, Yi; Liu, Zhenyu; Li, Manxia; Yang, Keshu; Ding, Chengbiao; Hsieh, Tsung-Hsun; Feng, Xiaojun

Year: 2026

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-025-07597-7

Paper Supplementation of spermidine enhances the quality of postovulatory aged porcine oocytes.

Bai, Jie; Zhang, Yu; Li, Na et al. · 2024 · Cell communication and signaling : CCS · DOI

Full title: Supplementation of spermidine enhances the quality of postovulatory aged porcine oocytes.

Authors: Bai, Jie; Zhang, Yu; Li, Na; Cui, Zhaokang; Zhang, Hanwen; Liu, Yiting; Miao, Yilong; Sun, Shaochen; Xiong, Bo

Year: 2024

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-024-01881-7

Paper Pbk positively regulates myoblast differentiation and muscle regeneration via enhancing AMPK/ULK1 mediated myogenic autophagy.

Wang, Dongdong; Shan, Didi; Zhao, Dandan et al. · 2025 · Journal of translational medicine · DOI

Full title: Pbk positively regulates myoblast differentiation and muscle regeneration via enhancing AMPK/ULK1 mediated myogenic autophagy.

Authors: Wang, Dongdong; Shan, Didi; Zhao, Dandan; Dai, Tingjun; Liu, Fuchen; Yan, Chuanzhu

Year: 2025

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-025-07173-z

Paper Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans.

Kumar, Arun; Saha, Manti Kumar; Kumar, Vipin et al. · 2024 · Immunity & ageing : I & A · DOI

Full title: Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans.

Authors: Kumar, Arun; Saha, Manti Kumar; Kumar, Vipin; Bhattacharya, Anupam; Barge, Sagar; Mukherjee, Ashis K; Kalita, Mohan C; Khan, Mojibur R

Year: 2024

Venue: Immunity & ageing : I & A

DOI: https://doi.org/10.1186/s12979-024-00457-w

Paper Erratum to: Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy.

Zhang, Lei; Ding, Wen-Yuan; Wang, Zhi-Hao et al. · 2016 · Journal of translational medicine · DOI

Full title: Erratum to: Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy.

Authors: Zhang, Lei; Ding, Wen-Yuan; Wang, Zhi-Hao; Tang, Meng-Xiong; Wang, Feng; Li, Ya; Zhong, Ming; Zhang, Yun; Zhang, Wei

Year: 2016

Venue: Journal of translational medicine

DOI: https://doi.org/10.1186/s12967-016-1068-5

Paper Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Niu, Qingru; Chen, Huan; Ou, Qianmin et al. · 2023 · Journal of orthopaedic surgery and research · DOI

Full title: Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Authors: Niu, Qingru; Chen, Huan; Ou, Qianmin; Yang, Shuqing; Peng, Yingying; Xie, Yunyi; Yu, Le; Cheng, Zhilan; Cao, Yang; Wang, Yan

Year: 2023

Venue: Journal of orthopaedic surgery and research

DOI: https://doi.org/10.1186/s13018-023-03849-8

Paper Glucocerebrosidase and its relevance to Parkinson disease

Do, Jenny; McKinney, Cindy E.; Sharma, Pankaj et al. · 2019 · Molecular Neurodegeneration · DOI

Full title: Glucocerebrosidase and its relevance to Parkinson disease

Authors: Do, Jenny; McKinney, Cindy E.; Sharma, Pankaj; Sidransky, Ellen

Year: 2019

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/s13024-019-0336-2

Paper Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.

Jia, Lidan; Liu, Xuefang; Liu, Xinguang et al. · 2024 · Chinese medicine · DOI

Full title: Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.

Authors: Jia, Lidan; Liu, Xuefang; Liu, Xinguang; Guan, Qingzhou; Tian, Yange; Li, Jiansheng; Zhao, Peng

Year: 2024

Venue: Chinese medicine

DOI: https://doi.org/10.1186/s13020-024-00905-1

Paper Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc

Koh, Jae‐Young; Kim, Hana; Hwang, Jung Jin et al. · 2019 · Molecular Brain · DOI

Full title: Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc

Authors: Koh, Jae‐Young; Kim, Hana; Hwang, Jung Jin; Kim, Yang Hee; Park, Sang Eun

Year: 2019

Venue: Molecular Brain

DOI: https://doi.org/10.1186/s13041-019-0439-2

Paper Current strategies in the management of dementia with lewy bodies and future directions based on disease pathophysiology.

Erskine, Daniel; Taylor, John-Paul · 2025 · Molecular neurodegeneration · DOI

Full title: Current strategies in the management of dementia with lewy bodies and future directions based on disease pathophysiology.

Authors: Erskine, Daniel; Taylor, John-Paul

Year: 2025

Venue: Molecular neurodegeneration

DOI: https://doi.org/10.1186/s13024-025-00856-7

Paper Therapeutic potential of autophagy-enhancing agents in Parkinson's disease.

Moors, Tim E; Hoozemans, Jeroen J M; Ingrassia, Angela et al. · 2017 · Molecular neurodegeneration · DOI

Full title: Therapeutic potential of autophagy-enhancing agents in Parkinson's disease.

Authors: Moors, Tim E; Hoozemans, Jeroen J M; Ingrassia, Angela; Beccari, Tommaso; Parnetti, Lucilla; Chartier-Harlin, Marie-Christine; van de Berg, Wilma D J

Year: 2017

Venue: Molecular neurodegeneration

DOI: https://doi.org/10.1186/s13024-017-0154-3

Paper Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.

Son, Sung Min; Kang, Seokjo; Choi, Heesun et al. · 2015 · Molecular neurodegeneration · DOI

Full title: Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.

Authors: Son, Sung Min; Kang, Seokjo; Choi, Heesun; Mook-Jung, Inhee

Year: 2015

Venue: Molecular neurodegeneration

DOI: https://doi.org/10.1186/s13024-015-0054-3

Paper The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

Suk, Terry R.; Rousseaux, Maxime W.C. · 2020 · Molecular Neurodegeneration · DOI

Full title: The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

Authors: Suk, Terry R.; Rousseaux, Maxime W.C.

Year: 2020

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/s13024-020-00397-1

Paper Alcohol-associated liver disease

Mackowiak, Bryan; Fu, Yaojie; Maccioni, Luca et al. · 2024 · Journal of Clinical Investigation · DOI

Full title: Alcohol-associated liver disease

Authors: Mackowiak, Bryan; Fu, Yaojie; Maccioni, Luca; Gao, Bin

Year: 2024

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci176345

Paper Biological aging processes underlying cognitive decline and neurodegenerative disease

Gonzales, Mitzi M.; Garbarino, Valentina R.; Pollet, Erin et al. · 2022 · Journal of Clinical Investigation · DOI

Full title: Biological aging processes underlying cognitive decline and neurodegenerative disease

Authors: Gonzales, Mitzi M.; Garbarino, Valentina R.; Pollet, Erin; Palavicini, Juan Pablo; Kellogg, Dean L.; Kraig, Ellen; Orr, Miranda E.

Year: 2022

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci158453

Paper The role of mitochondria in aging

Jang, Ji Yong; Blum, Arnon; Liu, Jie et al. · 2018 · Journal of Clinical Investigation · DOI

Full title: The role of mitochondria in aging

Authors: Jang, Ji Yong; Blum, Arnon; Liu, Jie; Finkel, Toren

Year: 2018

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci120842

Paper Oligonucleotide therapeutic approaches for Huntington disease

Sah, Dinah W.Y.; Aronin, Neil · 2011 · Journal of Clinical Investigation · DOI

Full title: Oligonucleotide therapeutic approaches for Huntington disease

Authors: Sah, Dinah W.Y.; Aronin, Neil

Year: 2011

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci45130

Paper Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction

Lam, Hilaire C.; Cloonan, Suzanne M.; Bhashyam, Abhiram R. et al. · 2013 · Journal of Clinical Investigation · DOI

Full title: Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction

Authors: Lam, Hilaire C.; Cloonan, Suzanne M.; Bhashyam, Abhiram R.; Haspel, Jeffery A.; Singh, Anju; Sathirapongsasuti, J. Fah; Cervo, Morgan; Yao, Hongwei; Chung, Anna L.; Mizumura, Kenji; An, Chang Hyeok; Shan, Bin; Franks, Jonathan; Haley, Kathleen J.; Owen, Caroline A.; Tesfaigzi, Yohannes; Washko, George R.; Quackenbush, John; Silverman, Edwin K.; Rahman, Irfan; Kim, Hong Pyo; Mahmood, Ashfaq; Biswal, Shyam; Ryter, Stefan W.; Choi, Augustine M.K.

Year: 2013

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci69636

Paper The cellular response to aggregated proteins associated with human disease.

· 2002 · Journal of Clinical Investigation · DOI

Full title: The cellular response to aggregated proteins associated with human disease.

Year: 2002

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci16780

Paper Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy.

Tao, Xianzun; Liu, Jiaqi; Diaz-Perez, Zoraida et al. · 2023 · bioRxiv : the preprint server for biology · DOI

Full title: Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy.

Authors: Tao, Xianzun; Liu, Jiaqi; Diaz-Perez, Zoraida; Foley, Jackson R; Stewart, Tracy Murray; Casero, Robert A; Zhai, R Grace

Year: 2023

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.03.17.533015

Paper Unlocking a New Path: An Autophagometer that Measures Flux Using a Non-Fluorescent Immunohistochemistry Method.

Shojaei, Shahla; Barzegar Behrooz, Amir; Cordani, Marco et al. · 2024 · bioRxiv : the preprint server for biology · DOI

Full title: Unlocking a New Path: An Autophagometer that Measures Flux Using a Non-Fluorescent Immunohistochemistry Method.

Authors: Shojaei, Shahla; Barzegar Behrooz, Amir; Cordani, Marco; Aghaei, Mahmood; Azarpira, Negar; Klionsky, Daniel J; Ghavami, Saeid

Year: 2024

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2024.06.26.600741

Paper Aging as an Event of Proteostasis Collapse

Taylor, Rebecca C.; Dillin, Andrew · 2011 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: Aging as an Event of Proteostasis Collapse

Authors: Taylor, Rebecca C.; Dillin, Andrew

Year: 2011

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a004440

Paper Multiple Functions of BCL-2 Family Proteins

Hardwick, J. Marie; Soane, Lucian · 2013 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: Multiple Functions of BCL-2 Family Proteins

Authors: Hardwick, J. Marie; Soane, Lucian

Year: 2013

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a008722

Paper XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

Hetz, Claudio; Thielen, Peter; Matus, Soledad et al. · 2009 · Genes & Development · DOI

Full title: XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

Authors: Hetz, Claudio; Thielen, Peter; Matus, Soledad; Nassif, Melissa; Court, Felipe A.; Kiffin, Roberta; Martínez, Gabriela; Cuervo, Ana María; Brown, Robert H.; Glimcher, Laurie H.

Year: 2009

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.1830709

Paper The Autophagy Lysosomal Pathway and Neurodegeneration

Finkbeiner, Steven · 2019 · Cold Spring Harbor Perspectives in Biology · DOI

Full title: The Autophagy Lysosomal Pathway and Neurodegeneration

Authors: Finkbeiner, Steven

Year: 2019

Venue: Cold Spring Harbor Perspectives in Biology

DOI: https://doi.org/10.1101/cshperspect.a033993

Paper Calorie restriction and sirtuins revisited

Guarente, Leonard · 2013 · Genes & Development · DOI

Full title: Calorie restriction and sirtuins revisited

Authors: Guarente, Leonard

Year: 2013

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.227439.113

Paper The emerging role of the Nrf2–Keap1 signaling pathway in cancer

Jaramillo, Melba C.; Zhang, Donna D. · 2013 · Genes & Development · DOI

Full title: The emerging role of the Nrf2–Keap1 signaling pathway in cancer

Authors: Jaramillo, Melba C.; Zhang, Donna D.

Year: 2013

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.225680.113

Paper Autophagy and Diabetic Encephalopathy: Mechanistic Insights and Potential Therapeutic Implications.

Cheng, Li-Zhen; Li, Wei; Chen, Yi-Xin et al. · 2022 · Aging and disease · DOI

Full title: Autophagy and Diabetic Encephalopathy: Mechanistic Insights and Potential Therapeutic Implications.

Authors: Cheng, Li-Zhen; Li, Wei; Chen, Yi-Xin; Lin, Yi-Jia; Miao, Ya

Year: 2022

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2021.0823

Paper Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Joshi, Amit U.; Saw, Nay L.; Vogel, Hannes et al. · 2018 · EMBO Molecular Medicine · DOI

Full title: Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Authors: Joshi, Amit U.; Saw, Nay L.; Vogel, Hannes; Cunnigham, Anna D; Shamloo, Mehrdad; Mochly‐Rosen, Daria

Year: 2018

Venue: EMBO Molecular Medicine

DOI: https://doi.org/10.15252/emmm.201708166

Paper Emerging roles of ATG7 in human health and disease

Collier, Jack J.; Suomi, Fumi; Oláhová, Monika et al. · 2021 · EMBO Molecular Medicine · DOI

Full title: Emerging roles of ATG7 in human health and disease

Authors: Collier, Jack J.; Suomi, Fumi; Oláhová, Monika; McWilliams, Thomas G.; Taylor, Robert W.

Year: 2021

Venue: EMBO Molecular Medicine

DOI: https://doi.org/10.15252/emmm.202114824

Paper The adaptation of SARS-CoV-2 to humans.

Tosta, Eduardo · 2022 · Memorias do Instituto Oswaldo Cruz · DOI

Full title: The adaptation of SARS-CoV-2 to humans.

Authors: Tosta, Eduardo

Year: 2022

Venue: Memorias do Instituto Oswaldo Cruz

DOI: https://doi.org/10.1590/0074-02760210127

Paper KLF5 Alleviates Excessive Autophagy-Induced Podocyte Injury by Enhancing ITCH-Mediated Ubiquitination of ACTR2.

Lin, Xianchu; Lin, Huirong; Luo, Man et al. · 2025 · The Tohoku journal of experimental medicine · DOI

Full title: KLF5 Alleviates Excessive Autophagy-Induced Podocyte Injury by Enhancing ITCH-Mediated Ubiquitination of ACTR2.

Authors: Lin, Xianchu; Lin, Huirong; Luo, Man; Han, Jun; Hu, Yan; Xiang, Shilong; Fang, Zejun

Year: 2025

Venue: The Tohoku journal of experimental medicine

DOI: https://doi.org/10.1620/tjem.2025.J122

Paper Another "Janus paradox" of p53: induction of cell senescence versus quiescence

Z. Darżynkiewicz · 2010 · Aging · DOI

Full title: Another "Janus paradox" of p53: induction of cell senescence versus quiescence

Authors: Z. Darżynkiewicz

Year: 2010

Venue: Aging

DOI: https://doi.org/10.18632/aging.100165

Paper Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

Wu, Jinming; Quijano, Celia; Chen, Edmund et al. · 2009 · Aging · DOI

Full title: Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

Authors: Wu, Jinming; Quijano, Celia; Chen, Edmund; Liu, Hongjun; Cao, Liu; Fergusson, Marı́a M.; Rovira, Ilsa I.; Gutkind, Sarah; Daniels, Mathew P.; Komatsu, Masaaki; Finkel, Toren

Year: 2009

Venue: Aging

DOI: https://doi.org/10.18632/aging.100038

Paper Polyamines in aging and disease

Minois, Nadège; Carmona‐Gutiérrez, Didac; Madeo, Frank · 2011 · Aging · DOI

Full title: Polyamines in aging and disease

Authors: Minois, Nadège; Carmona‐Gutiérrez, Didac; Madeo, Frank

Year: 2011

Venue: Aging

DOI: https://doi.org/10.18632/aging.100361

Paper Why Cell Reprogramming is Functionally Linked to Aging?

Jian Zhao; G. Pei · 2011 · Aging · DOI

Full title: Why Cell Reprogramming is Functionally Linked to Aging?

Authors: Jian Zhao; G. Pei

Year: 2011

Venue: Aging

DOI: https://doi.org/10.18632/aging.100364

Paper HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB.

Zou, Luetao; Lei, Hongyan; Shen, Jieliang et al. · 2020 · Aging · DOI

Full title: HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB.

Authors: Zou, Luetao; Lei, Hongyan; Shen, Jieliang; Liu, Xulin; Zhang, Xiang; Wu, Longxi; Hao, Jie; Jiang, Wei; Hu, Zhenming

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.102753

Paper Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1.

Rong, Yuluo; Liu, Wei; Lv, Chengtang et al. · 2019 · Aging · DOI

Full title: Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1.

Authors: Rong, Yuluo; Liu, Wei; Lv, Chengtang; Wang, Jiaxing; Luo, Yongjun; Jiang, Dongdong; Li, Linwei; Zhou, Zheng; Zhou, Wei; Li, Qingqing; Yin, Guoyong; Yu, Lipeng; Fan, Jin; Cai, Weihua

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.102283

Paper Lumbar puncture-administered resveratrol inhibits STAT3 activation, enhancing autophagy and apoptosis in orthotopic rat glioblastomas.

Xue, Song; Xiao-Hong, Shu; Lin, Sha et al. · 2016 · Oncotarget · DOI

Full title: Lumbar puncture-administered resveratrol inhibits STAT3 activation, enhancing autophagy and apoptosis in orthotopic rat glioblastomas.

Authors: Xue, Song; Xiao-Hong, Shu; Lin, Sha; Jie, Bian; Li-Li, Wang; Jia-Yao, Gu; Shun, Shi; Pei-Nan, Li; Mo-Li, Wu; Qian, Wang; Xiao-Yan, Chen; Qing-You, Kong; Peng, Zhang; Hong, Li; Jia, Liu

Year: 2016

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.12414

Paper Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.

Yang, Liu; Wang, Qijun; Zhao, Qian et al. · 2022 · Aging · DOI

Full title: Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.

Authors: Yang, Liu; Wang, Qijun; Zhao, Qian; Yang, Fan; Liu, Tingjiao; Huang, Xiaohua; Yan, Qiu; Yang, Xuesong

Year: 2022

Venue: Aging

DOI: https://doi.org/10.18632/aging.203795

Paper Sesn-1 is required for lifespan extension during caloric deprivation in C. elegans through inhibition of mTORC1 and activation of autophagy.

Zheltukhin, Andrei O; Chumakov, Peter M; Budanov, Andrei V · 2025 · Aging · DOI

Full title: Sesn-1 is required for lifespan extension during caloric deprivation in C. elegans through inhibition of mTORC1 and activation of autophagy.

Authors: Zheltukhin, Andrei O; Chumakov, Peter M; Budanov, Andrei V

Year: 2025

Venue: Aging

DOI: https://doi.org/10.18632/aging.206290

Paper Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation.

Liu, Feng; Zhang, Jin; Qin, Long et al. · 2018 · Aging · DOI

Full title: Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation.

Authors: Liu, Feng; Zhang, Jin; Qin, Long; Yang, Ziyao; Xiong, Jianxia; Zhang, Yanyan; Li, Ruihuan; Li, Shujing; Wang, Huifang; Yu, Bo; Zhao, Wenjun; Wang, Weiran; Li, Zhensu; Liu, Jing

Year: 2018

Venue: Aging

DOI: https://doi.org/10.18632/aging.101674

Paper Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.

Liang, Jie; Zhou, Fanlin; Xiong, Xiaomin et al. · 2019 · Aging · DOI

Full title: Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.

Authors: Liang, Jie; Zhou, Fanlin; Xiong, Xiaomin; Zhang, Xiong; Li, Shijie; Li, Xiaoju; Gao, Minna; Li, Yu

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.102235

Paper Advances in autophagy for Parkinson's disease pathogenesis and treatment.

Zhang, Xiaojie; Zhang, Huan; Dong, Jie et al. · 2025 · Ageing and neurodegenerative diseases · DOI

Full title: Advances in autophagy for Parkinson's disease pathogenesis and treatment.

Authors: Zhang, Xiaojie; Zhang, Huan; Dong, Jie; Cai, Huaibin; Le, Weidong

Year: 2025

Venue: Ageing and neurodegenerative diseases

DOI: https://doi.org/10.20517/and.2024.33

Paper The ROS/NF-κB/NR4A2 pathway is involved in H2O2 induced apoptosis of resident cardiac stem cells via autophagy.

Shi, Xingxing; Li, Wenjing; Liu, Honghong et al. · 2017 · Oncotarget · DOI

Full title: The ROS/NF-κB/NR4A2 pathway is involved in H2O2 induced apoptosis of resident cardiac stem cells via autophagy.

Authors: Shi, Xingxing; Li, Wenjing; Liu, Honghong; Yin, Deling; Zhao, Jing

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.20747

Paper Role of FOXO1 in aldosterone-induced autophagy: a compensatory protective mechanism related to podocyte injury.

Wang, Bin; Ding, Wei; Zhang, Minmin et al. · 2016 · Oncotarget · DOI

Full title: Role of FOXO1 in aldosterone-induced autophagy: a compensatory protective mechanism related to podocyte injury.

Authors: Wang, Bin; Ding, Wei; Zhang, Minmin; Li, Hongmei; Guo, Honglei; Lin, Lilu; Chen, Jing; Gu, Yong

Year: 2016

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.9644

Paper Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy.

Ke, Jin; Wang, Jie; Wu, Xing et al. · 2022 · Clinical, cosmetic and investigational dermatology · DOI

Full title: Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy.

Authors: Ke, Jin; Wang, Jie; Wu, Xing; Yan, Yuehua

Year: 2022

Venue: Clinical, cosmetic and investigational dermatology

DOI: https://doi.org/10.2147/CCID.S367233

Paper High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

Yang, Huan; Wang, Haichao; Chavan, Sangeeta S. et al. · 2015 · Molecular Medicine · DOI

Full title: High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

Authors: Yang, Huan; Wang, Haichao; Chavan, Sangeeta S.; Andersson, Jan

Year: 2015

Venue: Molecular Medicine

DOI: https://doi.org/10.2119/molmed.2015.00087

Paper Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

Guo, Caixia; Yang, Man; Li, Jing et al. · 2016 · International Journal of Nanomedicine · DOI

Full title: Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

Authors: Guo, Caixia; Yang, Man; Li, Jing; Wang, Ji; Yu, Yang; Li, Yang; Duan, Junchao; Zhou, Xianqing; Li, Yanbo; ccmu.edu.cn, Zhiwei zwsun

Year: 2016

Venue: International Journal of Nanomedicine

DOI: https://doi.org/10.2147/ijn.s112030

Paper Inhibition of autophagy contributes to the toxicity of cadmium telluride quantum dots in Saccharomyces cerevisiae.

Fan, Junpeng; Shao, Ming; Lai, Lu et al. · 2016 · International journal of nanomedicine · DOI

Full title: Inhibition of autophagy contributes to the toxicity of cadmium telluride quantum dots in Saccharomyces cerevisiae.

Authors: Fan, Junpeng; Shao, Ming; Lai, Lu; Liu, Yi; Xie, Zhixiong

Year: 2016

Venue: International journal of nanomedicine

DOI: https://doi.org/10.2147/IJN.S108636

Paper The Anti-Cancer Mechanisms of Berberine: A Review

Wang, Ye; Liu, Yanfang; Du, Xinyang et al. · 2020 · Cancer Management and Research · DOI

Full title: The Anti-Cancer Mechanisms of Berberine: A Review

Authors: Wang, Ye; Liu, Yanfang; Du, Xinyang; Ma, Hong; Yao, Jing

Year: 2020

Venue: Cancer Management and Research

DOI: https://doi.org/10.2147/cmar.s242329

Paper Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications

Zhang, Yi; Bi, Jia-Yao; Huang, Jiayi et al. · 2020 · International Journal of Nanomedicine · DOI

Full title: Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications

Authors: Zhang, Yi; Bi, Jia-Yao; Huang, Jiayi; Tang, Yanan; Du, Shouying; Li, Pengyue

Year: 2020

Venue: International Journal of Nanomedicine

DOI: https://doi.org/10.2147/ijn.s264498

Paper AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer's Disease by Enhancing Autophagy.

Deng, Yang; Wang, Si-Yu; Wang, Qing-Guang et al. · 2023 · Journal of inflammation research · DOI

Full title: AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer's Disease by Enhancing Autophagy.

Authors: Deng, Yang; Wang, Si-Yu; Wang, Qing-Guang; Xu, Zhao-Han; Peng, Qiang; Chen, Shuai-Yu; Zhu, Lin; Zhang, Ying-Dong; Duan, Rui

Year: 2023

Venue: Journal of inflammation research

DOI: https://doi.org/10.2147/JIR.S392599

Paper Hepatocyte-Targeted Epicatechin Nanoparticles Promote Autophagy and Enhance Mitochondrial Function in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Han, Daewon; Lee, Hyeji; Lee, Solji et al. · 2025 · International journal of nanomedicine · DOI

Full title: Hepatocyte-Targeted Epicatechin Nanoparticles Promote Autophagy and Enhance Mitochondrial Function in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Authors: Han, Daewon; Lee, Hyeji; Lee, Solji; Lee, Kyubae; Lee, Nam-Kyung; Jin, Tae-Eun; Lee, Junguee; Kim, Jong-Seok; Kim, Do Kyung; Shin, Jongdae; Park, Hwan-Woo

Year: 2025

Venue: International journal of nanomedicine

DOI: https://doi.org/10.2147/IJN.S557902

Paper Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.

Mao, Yingxuan; Du, Xinling; Wang, Weidong et al. · 2025 · International journal of nanomedicine · DOI

Full title: Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.

Authors: Mao, Yingxuan; Du, Xinling; Wang, Weidong; Dong, Tianxiu; Zhu, Mingwei; Niu, Jiamei; Li, Mingming; Jiang, Jian; Han, Linlin; Yang, Xiuhua

Year: 2025

Venue: International journal of nanomedicine

DOI: https://doi.org/10.2147/IJN.S536620

Paper Central nervous system toxicity of metallic nanoparticles

Wei, Limin; Shao, Longquan; Feng, Xiaoli et al. · 2015 · International Journal of Nanomedicine · DOI

Full title: Central nervous system toxicity of metallic nanoparticles

Authors: Wei, Limin; Shao, Longquan; Feng, Xiaoli; Chen, Aijie; Zhang, Yanli; Wang, Jianfeng

Year: 2015

Venue: International Journal of Nanomedicine

DOI: https://doi.org/10.2147/ijn.s78308

Paper Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.

Li, Chunyan; Zhu, Yuehua; Wu, Yuanyuan et al. · 2021 · Frontiers in medicine · DOI

Full title: Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.

Authors: Li, Chunyan; Zhu, Yuehua; Wu, Yuanyuan; Fu, Meiyuan; Wu, Yiling; Wu, Yuehong; Qiu, Yinger; Zhang, Hui; Ding, Mingxing

Year: 2021

Venue: Frontiers in medicine

DOI: https://doi.org/10.3389/fmed.2021.813047

Paper Therapeutic Mechanisms of Berberine to Improve the Intestinal Barrier Function via Modulating Gut Microbiota, TLR4/NF-κ B/MTORC Pathway and Autophagy in Cats.

Cao, JingWen; Chen, MiaoYu; Xu, Ran et al. · 2022 · Frontiers in microbiology · DOI

Full title: Therapeutic Mechanisms of Berberine to Improve the Intestinal Barrier Function via Modulating Gut Microbiota, TLR4/NF-κ B/MTORC Pathway and Autophagy in Cats.

Authors: Cao, JingWen; Chen, MiaoYu; Xu, Ran; Guo, MengYao

Year: 2022

Venue: Frontiers in microbiology

DOI: https://doi.org/10.3389/fmicb.2022.961885

Paper ER stress, autophagy, and RNA viruses

Jheng, Jia-Rong; Ho, Jin‐Yuan; Horng, Jim‐Tong · 2014 · Frontiers in Microbiology · DOI

Full title: ER stress, autophagy, and RNA viruses

Authors: Jheng, Jia-Rong; Ho, Jin‐Yuan; Horng, Jim‐Tong

Year: 2014

Venue: Frontiers in Microbiology

DOI: https://doi.org/10.3389/fmicb.2014.00388

Paper TLR7 Stimulation With Imiquimod Induces Selective Autophagy and Controls Mycobacterium tuberculosis Growth in Mouse Macrophages.

Lee, Hyo-Ji; Kang, Su-Jin; Woo, Yunseo et al. · 2020 · Frontiers in microbiology · DOI

Full title: TLR7 Stimulation With Imiquimod Induces Selective Autophagy and Controls Mycobacterium tuberculosis Growth in Mouse Macrophages.

Authors: Lee, Hyo-Ji; Kang, Su-Jin; Woo, Yunseo; Hahn, Tae-Wook; Ko, Hyun-Jeong; Jung, Yu-Jin

Year: 2020

Venue: Frontiers in microbiology

DOI: https://doi.org/10.3389/fmicb.2020.01684

Paper Dual role of complement in neuronal repair.

Lukomska, Agnieszka; Ciesielski, Peter; Ratajczak, Mariusz Z et al. · 2025 · Frontiers in immunology · DOI

Full title: Dual role of complement in neuronal repair.

Authors: Lukomska, Agnieszka; Ciesielski, Peter; Ratajczak, Mariusz Z; Kucia, Magdalena

Year: 2025

Venue: Frontiers in immunology

DOI: https://doi.org/10.3389/fimmu.2025.1712452

Paper The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches

Geloso, Maria Concetta; Corvino, Valentina; Marchese, Elisa et al. · 2017 · Frontiers in Aging Neuroscience · DOI

Full title: The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches

Authors: Geloso, Maria Concetta; Corvino, Valentina; Marchese, Elisa; Serrano, Alessia; Michetti, Fabrizio; D’Ambrosi, Nadia

Year: 2017

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2017.00242

Paper Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis

Chakravorty, Anushka; Jetto, Cuckoo Teresa; Manjithaya, Ravi · 2019 · Frontiers in Aging Neuroscience · DOI

Full title: Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis

Authors: Chakravorty, Anushka; Jetto, Cuckoo Teresa; Manjithaya, Ravi

Year: 2019

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2019.00311

Paper The role of ATG16L1 in Crohn's disease and the structural alteration mechanisms and functional consequences of the rs2241880 variant.

Ren, Shijie; Wei, Wenli; Liu, Xingchi et al. · 2025 · Frontiers in medicine · DOI

Full title: The role of ATG16L1 in Crohn's disease and the structural alteration mechanisms and functional consequences of the rs2241880 variant.

Authors: Ren, Shijie; Wei, Wenli; Liu, Xingchi; Kang, Xin; Liu, Jingyuan; Zhai, Wenjing; Zhang, Yifan; Chuai, Qiang; Hu, Boqian; Liu, Jianping; Lang, Xiaomeng

Year: 2025

Venue: Frontiers in medicine

DOI: https://doi.org/10.3389/fmed.2025.1656575

Paper Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer's disease therapy.

Sreenivasmurthy, Sravan Gopalkrishnashetty; Iyaswamy, Ashok; Krishnamoorthi, Senthilkumar et al. · 2022 · Frontiers in molecular biosciences · DOI

Full title: Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer's disease therapy.

Authors: Sreenivasmurthy, Sravan Gopalkrishnashetty; Iyaswamy, Ashok; Krishnamoorthi, Senthilkumar; Reddi, Rambabu N; Kammala, Ananth Kumar; Vasudevan, Karthick; Senapati, Sanjib; Zhu, Zhou; Su, Cheng-Fu; Liu, Jia; Guan, Xin-Jie; Chua, Ka-Kit; Cheung, King-Ho; Chen, Hubiao; Zhang, Hong-Jie; Zhang, Yuan; Song, Ju-Xian; Kumar Durairajan, Siva Sundara; Li, Min

Year: 2022

Venue: Frontiers in molecular biosciences

DOI: https://doi.org/10.3389/fmolb.2022.1030534

Paper Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.

Li, Fengqin; Deng, Lishuang; Xu, Tong et al. · 2024 · Frontiers in microbiology · DOI

Full title: Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.

Authors: Li, Fengqin; Deng, Lishuang; Xu, Tong; Xu, Lei; Xu, Zhiwen; Lai, Siyuan; Ai, Yanru; Wang, Yanqun; Yan, Guangwen; Zhu, Ling

Year: 2024

Venue: Frontiers in microbiology

DOI: https://doi.org/10.3389/fmicb.2024.1519694

Paper Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficits Induced by Anesthesia/Surgery in Aged Mice.

Gao, Sunan; Zhang, Siyu; Zhou, Hongmei et al. · 2021 · Frontiers in aging neuroscience · DOI

Full title: Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficits Induced by Anesthesia/Surgery in Aged Mice.

Authors: Gao, Sunan; Zhang, Siyu; Zhou, Hongmei; Tao, Xiaoyan; Ni, Yunjian; Pei, Daqing; Kang, Shuai; Yan, Weiwei; Lu, Jian

Year: 2021

Venue: Frontiers in aging neuroscience

DOI: https://doi.org/10.3389/fnagi.2021.628541

Paper Updated insights into the NLRP3 inflammasome in postoperative cognitive dysfunction: emerging mechanisms and treatments.

Wang, Tian; Sun, Guangwei; Tao, Bingdong · 2024 · Frontiers in aging neuroscience · DOI

Full title: Updated insights into the NLRP3 inflammasome in postoperative cognitive dysfunction: emerging mechanisms and treatments.

Authors: Wang, Tian; Sun, Guangwei; Tao, Bingdong

Year: 2024

Venue: Frontiers in aging neuroscience

DOI: https://doi.org/10.3389/fnagi.2024.1480502

Paper Dual Role of Autophagy in Diseases of the Central Nervous System

Bar-Yosef, Tamara; Damri, Odeya; Agam, Galila · 2019 · Frontiers in Cellular Neuroscience · DOI

Full title: Dual Role of Autophagy in Diseases of the Central Nervous System

Authors: Bar-Yosef, Tamara; Damri, Odeya; Agam, Galila

Year: 2019

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2019.00196

Paper Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease

Misrani, Afzal; Tabassum, Sidra; Yang, Li · 2021 · Frontiers in Aging Neuroscience · DOI

Full title: Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease

Authors: Misrani, Afzal; Tabassum, Sidra; Yang, Li

Year: 2021

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2021.617588

Paper Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury

Shen, Luoan; Gan, Qinyi; Yang, Youcheng et al. · 2021 · Frontiers in Aging Neuroscience · DOI

Full title: Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury

Authors: Shen, Luoan; Gan, Qinyi; Yang, Youcheng; Reis, Cesar; Zhang, Zheng; Xu, Shanshan; Zhang, Tongyu; Sun, Chengmei

Year: 2021

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2021.687246

Paper Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis.

Zhou, Hongyi; Jiang, Fan; Leng, Yufang · 2021 · Frontiers in molecular biosciences · DOI

Full title: Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis.

Authors: Zhou, Hongyi; Jiang, Fan; Leng, Yufang

Year: 2021

Venue: Frontiers in molecular biosciences

DOI: https://doi.org/10.3389/fmolb.2021.695336

Paper Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease

Zeng, Xiansi; Geng, Wen-Shuo; Jia, Jing et al. · 2018 · Frontiers in Aging Neuroscience · DOI

Full title: Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease

Authors: Zeng, Xiansi; Geng, Wen-Shuo; Jia, Jing; Chen, Lei; Zhang, Peng-Peng

Year: 2018

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2018.00109

Paper The essential role of CCT2 in the regulation of aggrephagy.

Luo, Jie; Feng, Ze-Sen; Tang, Ji-Xin · 2024 · Frontiers in aging neuroscience · DOI

Full title: The essential role of CCT2 in the regulation of aggrephagy.

Authors: Luo, Jie; Feng, Ze-Sen; Tang, Ji-Xin

Year: 2024

Venue: Frontiers in aging neuroscience

DOI: https://doi.org/10.3389/fnagi.2024.1491001

Paper Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?

Fu, Kaijing; Xu, Weilin; Lenahan, Cameron et al. · 2022 · Frontiers in cellular neuroscience · DOI

Full title: Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?

Authors: Fu, Kaijing; Xu, Weilin; Lenahan, Cameron; Mo, Yong; Wen, Jing; Deng, Teng; Huang, Qianrong; Guo, Fangzhou; Mo, Ligen; Yan, Jun

Year: 2022

Venue: Frontiers in cellular neuroscience

DOI: https://doi.org/10.3389/fncel.2022.1036313

Paper Astrocytic modulation of blood brain barrier: perspectives on Parkinsonâ€™s disease

Cabezas, Ricardo; Ávila, Marcos Fidel; González, Janneth et al. · 2014 · Frontiers in Cellular Neuroscience · DOI

Full title: Astrocytic modulation of blood brain barrier: perspectives on Parkinsonâ€™s disease

Authors: Cabezas, Ricardo; Ávila, Marcos Fidel; González, Janneth; El-Bachá, Ramon dos Santos; BÃ¡ez, Eliana; García‐Segura, Luis Miguel; Jurado-Coronel, Juan Camilo; Capani, Francisco; Cardona‐Gómez, Gloria Patricia; Barreto, George E.

Year: 2014

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2014.00211

Paper Implications of glial nitric oxide in neurodegenerative diseases

Yuste, José Enrique; Tarragón, Ernesto; Campuzano, Carmen María et al. · 2015 · Frontiers in Cellular Neuroscience · DOI

Full title: Implications of glial nitric oxide in neurodegenerative diseases

Authors: Yuste, José Enrique; Tarragón, Ernesto; Campuzano, Carmen María; Ros‐Bernal, Francisco

Year: 2015

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2015.00322

Paper Enhancing autophagy mitigates LPS-induced neuroinflammation by inhibiting microglial M1 polarization and neuronophagocytosis.

Guo, Jingjing; Li, Yun; Ma, Kun et al. · 2025 · Frontiers in cellular neuroscience · DOI

Full title: Enhancing autophagy mitigates LPS-induced neuroinflammation by inhibiting microglial M1 polarization and neuronophagocytosis.

Authors: Guo, Jingjing; Li, Yun; Ma, Kun; Su, Guohai

Year: 2025

Venue: Frontiers in cellular neuroscience

DOI: https://doi.org/10.3389/fncel.2025.1546848

Paper GRP78 at the Centre of the Stage in Cancer and Neuroprotection

Casas, Caty · 2017 · Frontiers in Neuroscience · DOI

Full title: GRP78 at the Centre of the Stage in Cancer and Neuroprotection

Authors: Casas, Caty

Year: 2017

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2017.00177

Paper Iron in Neurodegeneration – Cause or Consequence?

Ndayisaba, Alain; Kaindlstorfer, Christine; Wenning, Gregor K. · 2019 · Frontiers in Neuroscience · DOI

Full title: Iron in Neurodegeneration – Cause or Consequence?

Authors: Ndayisaba, Alain; Kaindlstorfer, Christine; Wenning, Gregor K.

Year: 2019

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2019.00180

Paper Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease

Chesser, Adrianne S.; Pritchard, Susanne M.; Johnson, Gail V.W. · 2013 · Frontiers in Neurology · DOI

Full title: Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease

Authors: Chesser, Adrianne S.; Pritchard, Susanne M.; Johnson, Gail V.W.

Year: 2013

Venue: Frontiers in Neurology

DOI: https://doi.org/10.3389/fneur.2013.00122

Paper Protein Quality Control by Molecular Chaperones in Neurodegeneration

Ciechanover, Aaron; Kwon, Yong Tae · 2017 · Frontiers in Neuroscience · DOI

Full title: Protein Quality Control by Molecular Chaperones in Neurodegeneration

Authors: Ciechanover, Aaron; Kwon, Yong Tae

Year: 2017

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2017.00185

Paper Caffeine and Parkinson’s Disease: Multiple Benefits and Emerging Mechanisms

Ren, Xiangpeng; Chen, Jiang‐Fan · 2020 · Frontiers in Neuroscience · DOI

Full title: Caffeine and Parkinson’s Disease: Multiple Benefits and Emerging Mechanisms

Authors: Ren, Xiangpeng; Chen, Jiang‐Fan

Year: 2020

Venue: Frontiers in Neuroscience

DOI: https://doi.org/10.3389/fnins.2020.602697

Paper Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.

Liu, Xi-Yuan; Lu, Rui; Chen, Jing et al. · 2021 · Frontiers in neuroscience · DOI

Full title: Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.

Authors: Liu, Xi-Yuan; Lu, Rui; Chen, Jing; Wang, Jie; Qian, Hong-Mei; Chen, Gang; Wu, Rong-Han; Chi, Zai-Long

Year: 2021

Venue: Frontiers in neuroscience

DOI: https://doi.org/10.3389/fnins.2021.738022

Paper The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

Rusmini, Paola; Cristofani, Riccardo; Galbiati, Mariarita et al. · 2017 · Frontiers in molecular neuroscience · DOI

Full title: The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

Authors: Rusmini, Paola; Cristofani, Riccardo; Galbiati, Mariarita; Cicardi, Maria E; Meroni, Marco; Ferrari, Veronica; Vezzoli, Giulia; Tedesco, Barbara; Messi, Elio; Piccolella, Margherita; Carra, Serena; Crippa, Valeria; Poletti, Angelo

Year: 2017

Venue: Frontiers in molecular neuroscience

DOI: https://doi.org/10.3389/fnmol.2017.00176

Paper Usp14 down-regulation corrects sleep and circadian dysfunction of a Drosophila model of Parkinson's disease.

Favaro, Mariavittoria; Mauri, Sofia; Bernardo, Greta et al. · 2024 · Frontiers in neuroscience · DOI

Full title: Usp14 down-regulation corrects sleep and circadian dysfunction of a Drosophila model of Parkinson's disease.

Authors: Favaro, Mariavittoria; Mauri, Sofia; Bernardo, Greta; Zordan, Mauro A; Mazzotta, Gabriella M; Ziviani, Elena

Year: 2024

Venue: Frontiers in neuroscience

DOI: https://doi.org/10.3389/fnins.2024.1410139

Paper Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria.

Liu, Danping; Guo, Pei; Wang, Yi et al. · 2024 · Frontiers in molecular neuroscience · DOI

Full title: Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria.

Authors: Liu, Danping; Guo, Pei; Wang, Yi; Li, Weihong

Year: 2024

Venue: Frontiers in molecular neuroscience

DOI: https://doi.org/10.3389/fnmol.2024.1516119

Paper TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway.

Zhou, Wenjuan; Yao, Yuan; Li, Jinxing et al. · 2019 · Frontiers in molecular neuroscience · DOI

Full title: TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway.

Authors: Zhou, Wenjuan; Yao, Yuan; Li, Jinxing; Wu, Dong; Zhao, Man; Yan, Zongting; Pang, Aimei; Kong, Liang

Year: 2019

Venue: Frontiers in molecular neuroscience

DOI: https://doi.org/10.3389/fnmol.2019.00193

Paper Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities

Liu, Jie; Li, Lian · 2019 · Frontiers in Molecular Neuroscience · DOI

Full title: Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities

Authors: Liu, Jie; Li, Lian

Year: 2019

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2019.00203

Paper Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

Ramesh, Nandini; Pandey, Udai Bhan · 2017 · Frontiers in Molecular Neuroscience · DOI

Full title: Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

Authors: Ramesh, Nandini; Pandey, Udai Bhan

Year: 2017

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2017.00263

Paper Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

Fields, Carroll Rutherford; Bengoa‐Vergniory, Nora; Wade‐Martins, Richard · 2019 · Frontiers in Molecular Neuroscience · DOI

Full title: Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

Authors: Fields, Carroll Rutherford; Bengoa‐Vergniory, Nora; Wade‐Martins, Richard

Year: 2019

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2019.00299

Paper PKR: A Kinase to Remember

Gal-Ben-Ari, Shunit; Barrera, Iliana; Ehrlich, Marcelo et al. · 2019 · Frontiers in Molecular Neuroscience · DOI

Full title: PKR: A Kinase to Remember

Authors: Gal-Ben-Ari, Shunit; Barrera, Iliana; Ehrlich, Marcelo; Rosenblum, Kobi

Year: 2019

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2018.00480

Paper Pharmacological Activation of Autophagy Restores Cellular Homeostasis in Ultraviolet-(B)-Induced Skin Photodamage.

Umar, Sheikh Ahmad; Shahid, Naikoo Hussain; Nazir, Lone Ahmad et al. · 2021 · Frontiers in oncology · DOI

Full title: Pharmacological Activation of Autophagy Restores Cellular Homeostasis in Ultraviolet-(B)-Induced Skin Photodamage.

Authors: Umar, Sheikh Ahmad; Shahid, Naikoo Hussain; Nazir, Lone Ahmad; Tanveer, Malik Ahmad; Divya, Gupta; Archoo, Sajida; Raghu, Sharma Rai; Tasduq, Sheikh Abdullah

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.726066

Paper Harnessing Oncolytic Virus-Mediated Anti-Tumor Immunity

V. Schirrmacher; P. Fournier · 2014 · Frontiers in Oncology · DOI

Full title: Harnessing Oncolytic Virus-Mediated Anti-Tumor Immunity

Authors: V. Schirrmacher; P. Fournier

Year: 2014

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2014.00337

Paper The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.

Lin, Qimei; Cao, Jiasong; Du, Xiaoling et al. · 2021 · Frontiers in oncology · DOI

Full title: The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.

Authors: Lin, Qimei; Cao, Jiasong; Du, Xiaoling; Yang, Kuo; Shen, Yongmei; Wang, Weishu; Klocker, Helmut; Shi, Jiandang; Zhang, Ju

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.787953

Paper Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma.

Li, Qinglin; Xia, Liang; Sun, Caixing et al. · 2021 · Frontiers in oncology · DOI

Full title: Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma.

Authors: Li, Qinglin; Xia, Liang; Sun, Caixing; Zhang, Huangjie; Zheng, Mengying; Zhang, Hongyan; Lu, Hongyang; Wang, Zeng

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.749987

Paper HMGB1 Promotes Resistance to Doxorubicin in Human Hepatocellular Carcinoma Cells by Inducing Autophagy via the AMPK/mTOR Signaling Pathway.

Li, Junhua; Zhou, Wei; Mao, Qiang et al. · 2021 · Frontiers in oncology · DOI

Full title: HMGB1 Promotes Resistance to Doxorubicin in Human Hepatocellular Carcinoma Cells by Inducing Autophagy via the AMPK/mTOR Signaling Pathway.

Authors: Li, Junhua; Zhou, Wei; Mao, Qiang; Gao, Dandan; Xiong, Lin; Hu, Xinyao; Zheng, Yongfa; Xu, Ximing

Year: 2021

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2021.739145

Paper AXL Promotes Metformin-Induced Apoptosis Through Mediation of Autophagy by Activating ROS-AMPK-ULK1 Signaling in Human Esophageal Adenocarcinoma.

Hong, Jun; Maacha, Selma; Pidkovka, Nataliya et al. · 2022 · Frontiers in oncology · DOI

Full title: AXL Promotes Metformin-Induced Apoptosis Through Mediation of Autophagy by Activating ROS-AMPK-ULK1 Signaling in Human Esophageal Adenocarcinoma.

Authors: Hong, Jun; Maacha, Selma; Pidkovka, Nataliya; Bates, Andreia; Salaria, Safia N; Washington, Mary K; Belkhiri, Abbes

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.903874

Paper Emerging role of selective autophagy in human diseases.

Mizumura, Kenji; Choi, Augustine M K; Ryter, Stefan W · 2014 · Frontiers in pharmacology · DOI

Full title: Emerging role of selective autophagy in human diseases.

Authors: Mizumura, Kenji; Choi, Augustine M K; Ryter, Stefan W

Year: 2014

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2014.00244

Paper RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway.

Wang, Liwei; Shi, Jiazhong; Liu, Sha et al. · 2022 · Frontiers in oncology · DOI

Full title: RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway.

Authors: Wang, Liwei; Shi, Jiazhong; Liu, Sha; Huang, Yaqin; Ding, Hua; Zhao, Baixiong; Liu, Yuting; Wang, Wuxing; Yang, Jin; Chen, Zhiwen

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.915240

Paper Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.

Yi, Juan; Gong, Xia; Yin, Xiao-Yang et al. · 2022 · Frontiers in oncology · DOI

Full title: Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.

Authors: Yi, Juan; Gong, Xia; Yin, Xiao-Yang; Wang, Li; Hou, Jin-Xia; Chen, Jing; Xie, Bei; Chen, Gang; Wang, Li-Na; Wang, Xiao-Yuan; Wang, Da-Chun; Wei, Hu-Lai

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.988528

Paper β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

Sun, Xiaojuan; Chen, Weidong; Wang, Yan‐Dong · 2015 · Frontiers in Pharmacology · DOI

Full title: β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

Authors: Sun, Xiaojuan; Chen, Weidong; Wang, Yan‐Dong

Year: 2015

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2015.00221

Paper Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells.

Wang, Chunfei; Feng, Liang; Ma, Liang et al. · 2017 · Frontiers in pharmacology · DOI

Full title: Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells.

Authors: Wang, Chunfei; Feng, Liang; Ma, Liang; Chen, Haifeng; Tan, Xiaobin; Hou, Xuefeng; Song, Jie; Cui, Li; Liu, Dan; Chen, Juan; Yang, Nan; Wang, Jing; Liu, Ying; Zhao, Bingjie; Wang, Gang; Zhou, Yuanli; Jia, Xiaobin

Year: 2017

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2017.00172

Paper GZ17-6.02 kills prostate cancer cells in vitro and in vivo.

Booth, Laurence; Roberts, Jane L; West, Cameron et al. · 2022 · Frontiers in oncology · DOI

Full title: GZ17-6.02 kills prostate cancer cells in vitro and in vivo.

Authors: Booth, Laurence; Roberts, Jane L; West, Cameron; Dent, Paul

Year: 2022

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2022.1045459

Paper In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

Watt, Georgia; Karl, Tim · 2017 · Frontiers in Pharmacology · DOI

Full title: In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

Authors: Watt, Georgia; Karl, Tim

Year: 2017

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2017.00020

Paper Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.

Hou, Jun; Zheng, Dezhi; Xiao, Wenjing et al. · 2018 · Frontiers in pharmacology · DOI

Full title: Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.

Authors: Hou, Jun; Zheng, Dezhi; Xiao, Wenjing; Li, Dandan; Ma, Jie; Hu, Yonghe

Year: 2018

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2018.00383

Paper Applications of Ruthenium Complex in Tumor Diagnosis and Therapy

Lin, Ke; Zhao, Zizhuo; Bo, Huaben et al. · 2018 · Frontiers in Pharmacology · DOI

Full title: Applications of Ruthenium Complex in Tumor Diagnosis and Therapy

Authors: Lin, Ke; Zhao, Zizhuo; Bo, Huaben; Hao, Xiaojuan; Wang, Jinquan

Year: 2018

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2018.01323

Paper Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.

Sun, Xiaowei; Wang, Dongyan; Zhang, Tingting et al. · 2020 · Frontiers in pharmacology · DOI

Full title: Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.

Authors: Sun, Xiaowei; Wang, Dongyan; Zhang, Tingting; Lu, Xuejian; Duan, Fangfang; Ju, Lili; Zhuang, Xiaotong; Jiang, Xicheng

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00084

Paper Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway.

Lin, Jianzhen; Jiao, Ao; Lv, Wu et al. · 2019 · Frontiers in pharmacology · DOI

Full title: Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway.

Authors: Lin, Jianzhen; Jiao, Ao; Lv, Wu; Zhang, Chengshuo; Shi, Yue; Yang, Zhaoming; Sun, Ning; Li, Xiaohang; Zhang, Jialin

Year: 2019

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2019.00896

Paper Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.

Chen, Yan; Liu, Qingpu; Shan, Zengfu et al. · 2019 · Frontiers in pharmacology · DOI

Full title: Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.

Authors: Chen, Yan; Liu, Qingpu; Shan, Zengfu; Mi, Wangyang; Zhao, Yingying; Li, Meng; Wang, Baiyan; Zheng, Xiaoke; Feng, Weisheng

Year: 2019

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2019.01477

Paper Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.

Wang, Dong; Guo, Haoran; Yang, Huahong et al. · 2019 · Frontiers in pharmacology · DOI

Full title: Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.

Authors: Wang, Dong; Guo, Haoran; Yang, Huahong; Wang, Dongyin; Gao, Pujun; Wei, Wei

Year: 2019

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2019.01238

Paper Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling.

Fang, Yuwei; Shi, Kangpei; Lu, Haining et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling.

Authors: Fang, Yuwei; Shi, Kangpei; Lu, Haining; Lu, Lin; Qiu, Bo

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.632040

Paper The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents

Zhou, Jiabei; Kang, Yu; Chen, Lu et al. · 2020 · Frontiers in Pharmacology · DOI

Full title: The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents

Authors: Zhou, Jiabei; Kang, Yu; Chen, Lu; Wang, Hua; Liu, Junqing; Zeng, Su; Yu, Lushan

Year: 2020

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00343

Paper Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.

Zhou, Feiya; Zhang, Xian; Jiang, Liangfu et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.

Authors: Zhou, Feiya; Zhang, Xian; Jiang, Liangfu; Li, Shi; Chen, Yiheng; Wu, Jianbin

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.667524

Paper Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways.

Tian, Ruimin; Wang, Pinchao; Huang, Lihua et al. · 2020 · Frontiers in pharmacology · DOI

Full title: Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways.

Authors: Tian, Ruimin; Wang, Pinchao; Huang, Lihua; Li, Chuang; Lu, Zhaoyu; Lu, Zhisheng; Wu, Aijun; Bao, Kun; Mao, Wei; Huang, Qingming; Xu, Peng

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.537147

Paper Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.

Li, Xiaochen; Meng, Cheng; Han, Fei et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.

Authors: Li, Xiaochen; Meng, Cheng; Han, Fei; Yang, Juhong; Wang, Jingyu; Zhu, Yanjuan; Cui, Xiao; Zuo, Minxia; Xu, Jie; Chang, Baocheng

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.634365

Paper New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection.

Bellusci, Lorenza; Laurino, Annunziatina; Sabatini, Martina et al. · 2017 · Frontiers in pharmacology · DOI

Full title: New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection.

Authors: Bellusci, Lorenza; Laurino, Annunziatina; Sabatini, Martina; Sestito, Simona; Lenzi, Paola; Raimondi, Laura; Rapposelli, Simona; Biagioni, Francesca; Fornai, Francesco; Salvetti, Alessandra; Rossi, Leonardo; Zucchi, Riccardo; Chiellini, Grazia

Year: 2017

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2017.00905

Paper Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival.

Jiang, Jingtao; Jin, Jie; Lou, Junsheng et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival.

Authors: Jiang, Jingtao; Jin, Jie; Lou, Junsheng; Li, Jiafeng; Wu, Hongqiang; Cheng, Sheng; Dong, Chengji; Chen, Hongyu; Gao, Weiyang

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.653035

Paper Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells.

Zhang, Daowei; Wu, Jiawen; Wu, Jihong et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells.

Authors: Zhang, Daowei; Wu, Jiawen; Wu, Jihong; Zhang, Shenghai

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.667959

Paper Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.

Chen, Yifei; Yu, Fangpu; Zhang, Yu et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.

Authors: Chen, Yifei; Yu, Fangpu; Zhang, Yu; Li, Mengmeng; Di, Mingxue; Chen, Weijia; Liu, Xiaolin; Zhang, Yun; Zhang, Mei

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.673366

Paper Insights into the role of mitophagy in lung cancer: current evidence and perspectives.

Zhang, Xin; Yu, Dongzhi; Tang, Peng et al. · 2024 · Frontiers in pharmacology · DOI

Full title: Insights into the role of mitophagy in lung cancer: current evidence and perspectives.

Authors: Zhang, Xin; Yu, Dongzhi; Tang, Peng; Chen, Fengshou

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1420643

Paper HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans.

Lin, Hongru; Zhang, Chen; Gao, Yehui et al. · 2024 · Frontiers in pharmacology · DOI

Full title: HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans.

Authors: Lin, Hongru; Zhang, Chen; Gao, Yehui; Zhou, Yi; Ma, Botian; Jiang, Jinyun; Long, Xue; Yimamu, Nuerziya; Zhong, Kaixin; Li, Yingzi; Cui, Xianghuan; Wang, Hongbing

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1433030

Paper Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stress and autophagy-mediated pyroptosis.

Wu, Fangfang; Zhang, Renkan; Meng, Weiyang et al. · 2022 · Frontiers in pharmacology · DOI

Full title: Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stress and autophagy-mediated pyroptosis.

Authors: Wu, Fangfang; Zhang, Renkan; Meng, Weiyang; Liu, Lei; Tang, Yingdan; Lu, Leilei; Xia, Leilei; Zhang, Hongyu; Feng, Zhiguo; Chen, Daqing

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.862324

Paper Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats and palmitic acid-challenged KGN cells by modulating lipid metabolism.

Li, Tian; Wei, Yao; Jiao, Beibie et al. · 2024 · Frontiers in pharmacology · DOI

Full title: Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats and palmitic acid-challenged KGN cells by modulating lipid metabolism.

Authors: Li, Tian; Wei, Yao; Jiao, Beibie; Hao, Rui; Zhou, Beibei; Bian, Xinlan; Wang, Peijuan; Zhou, Yahong; Sun, Xia; Zhang, Jian

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1425844

Paper Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.

Xin, Ming; Gao, Qi; Xiang, Xindong et al. · 2022 · Frontiers in pharmacology · DOI

Full title: Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.

Authors: Xin, Ming; Gao, Qi; Xiang, Xindong; Xu, Juanjuan; Jiao, Yuhan; Li, Xuan; Zhang, Xianzhen; Jia, Xiuqin

Year: 2022

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2022.890974

Paper Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.

Hu, Jiaji; Ying, Hanglu; Yao, Jie et al. · 2021 · Frontiers in pharmacology · DOI

Full title: Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.

Authors: Hu, Jiaji; Ying, Hanglu; Yao, Jie; Yang, Longhe; Jin, Wenhui; Ma, Huabin; Li, Long; Zhao, Yufen

Year: 2021

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2021.744483

Paper Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.

Mao, Shuai; Chen, Peipei; Li, Ting et al. · 2018 · Frontiers in physiology · DOI

Full title: Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.

Authors: Mao, Shuai; Chen, Peipei; Li, Ting; Guo, Liheng; Zhang, Minzhou

Year: 2018

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2018.00589

Paper Targeting autophagy: polydatin's role in inducing cell death in AML.

Fu, Ping; Luo, Qing; Wang, Chao et al. · 2024 · Frontiers in pharmacology · DOI

Full title: Targeting autophagy: polydatin's role in inducing cell death in AML.

Authors: Fu, Ping; Luo, Qing; Wang, Chao; Chen, Liping; Dong, Chang; Yang, Ke; Wu, Guang

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1470217

Paper Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: a review.

Ntsapi, C; Weyers, M; Chinheya, R et al. · 2025 · Frontiers in pharmacology · DOI

Full title: Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: a review.

Authors: Ntsapi, C; Weyers, M; Chinheya, R; Jim, T; Matsabisa, M

Year: 2025

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2025.1748368

Paper Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.

Shen, Fei; Zheng, Yun-Sheng; Dong, Lan et al. · 2024 · Frontiers in pharmacology · DOI

Full title: Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.

Authors: Shen, Fei; Zheng, Yun-Sheng; Dong, Lan; Cao, Ziyang; Cao, Jie

Year: 2024

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2024.1500731

Paper Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR.

Huangfu, Yaru; Yu, Xiuxian; Wan, Chengyu et al. · 2023 · Frontiers in pharmacology · DOI

Full title: Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR.

Authors: Huangfu, Yaru; Yu, Xiuxian; Wan, Chengyu; Zhu, Yuda; Wei, Zeliang; Li, Fan; Wang, Yilan; Zhang, Kun; Li, Shiyi; Dong, Yuman; Li, Yangying; Niu, Hai; Xin, Guang; Huang, Wen

Year: 2023

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2023.1105726

Paper Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer's Disease Model.

Faikoglu, Gokhan; Saygisever-Faikoglu, Kübra; Ozbasak, Hande et al. · 2025 · Cureus · DOI

Full title: Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer's Disease Model.

Authors: Faikoglu, Gokhan; Saygisever-Faikoglu, Kübra; Ozbasak, Hande; Ugur, Sedat Askin; Uskur, Tugce; Akkan, Ahmet Gökhan; Kelicen-Ugur, Pelin; Ozyazgan, Sibel

Year: 2025

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.88449

Paper Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

Yang, Yang; Wang, Huanan; Kouadir, Mohammed et al. · 2019 · Cell Death and Disease · DOI

Full title: Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

Authors: Yang, Yang; Wang, Huanan; Kouadir, Mohammed; Song, Houhui; Shi, Fushan

Year: 2019

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-019-1413-8

Paper Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.

Xue, Wenjing; Xu, Caili; Zhang, Kaiqi et al. · 2024 · Cell death discovery · DOI

Full title: Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.

Authors: Xue, Wenjing; Xu, Caili; Zhang, Kaiqi; Cui, Lu; Huang, Xiting; Nan, Yanyang; Ju, Dianwen; Chang, Xusheng; Zhang, Xuyao

Year: 2024

Venue: Cell death discovery

DOI: https://doi.org/10.1038/s41420-024-02167-0

Paper A self-destructive nanosweeper that captures and clears amyloid β-peptides

Luo, Qiang; Lin, Yao‐Xin; Yang, Pei‐Pei et al. · 2018 · Nature Communications · DOI

Full title: A self-destructive nanosweeper that captures and clears amyloid β-peptides

Authors: Luo, Qiang; Lin, Yao‐Xin; Yang, Pei‐Pei; Wang, Yi; Qi, Guobin; Qiao, Zeng‐Ying; Li, Bingnan; Zhang, Kuo; Zhang, Jingping; Wang, Lei; Wang, Hao

Year: 2018

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-018-04255-z

Paper MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.

Xing, Lei; Bu, Yu; Shi, Jingqi et al. · 2025 · Lipids in health and disease · DOI

Full title: MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.

Authors: Xing, Lei; Bu, Yu; Shi, Jingqi; Liu, Jing; Hu, Fan; Zhang, Minghua; Fan, Jiao

Year: 2025

Venue: Lipids in health and disease

DOI: https://doi.org/10.1186/s12944-025-02683-7

Paper Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy.

Tian, He; Zhao, Haosen; Mei, Xifan et al. · 2021 · Iranian journal of basic medical sciences · DOI

Full title: Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy.

Authors: Tian, He; Zhao, Haosen; Mei, Xifan; Li, Daoyong; Lin, Jiaquan; Lin, Sen; Song, Changwei

Year: 2021

Venue: Iranian journal of basic medical sciences

DOI: https://doi.org/10.22038/ijbms.2020.44534.10416

Paper Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells.

Zhou, Jianhua; Li, Shengyou; Gao, Jianbo et al. · 2020 · Frontiers in cellular neuroscience · DOI

Full title: Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells.

Authors: Zhou, Jianhua; Li, Shengyou; Gao, Jianbo; Hu, Yawei; Chen, Shaochu; Luo, Xinle; Zhang, Hao; Luo, Zhuojing; Huang, Jinghui

Year: 2020

Venue: Frontiers in cellular neuroscience

DOI: https://doi.org/10.3389/fncel.2020.00143

Paper Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum.

Luan, Yanan; Ren, Xiangpeng; Zheng, Wu et al. · 2018 · Frontiers in neuroscience · DOI

Full title: Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum.

Authors: Luan, Yanan; Ren, Xiangpeng; Zheng, Wu; Zeng, Zhenhai; Guo, Yingzi; Hou, Zhidong; Guo, Wei; Chen, Xingjun; Li, Fei; Chen, Jiang-Fan

Year: 2018

Venue: Frontiers in neuroscience

DOI: https://doi.org/10.3389/fnins.2018.00301

Paper Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model.

Liu, Yongda; Wang, Shuang; Wang, Zhibin et al. · 2020 · Frontiers in neuroscience · DOI

Full title: Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model.

Authors: Liu, Yongda; Wang, Shuang; Wang, Zhibin; Ding, Mengmeng; Li, Xingyue; Guo, Jiao; Han, Guang; Zhao, Ping

Year: 2020

Venue: Frontiers in neuroscience

DOI: https://doi.org/10.3389/fnins.2020.00090

Paper Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway.

Zhao, Yuan; Feng, Xiujing; Li, Bei et al. · 2020 · Frontiers in pharmacology · DOI

Full title: Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway.

Authors: Zhao, Yuan; Feng, Xiujing; Li, Bei; Sha, Jichen; Wang, Chaoran; Yang, Tianyuan; Cui, Hailin; Fan, Honggang

Year: 2020

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2020.00128

Paper PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease

Long, Hui‐Zhi; Cheng, Yan; Zhou, Ziwei et al. · 2021 · Frontiers in Pharmacology · DOI

Full title: PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease

Authors: Long, Hui‐Zhi; Cheng, Yan; Zhou, Ziwei; Luo, Hongyu; Wen, Dan‐Dan; Gao, Lichen

Year: 2021

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2021.648636

Paper Artesunate Exerts Organ- and Tissue-Protective Effects by Regulating Oxidative Stress, Inflammation, Autophagy, Apoptosis, and Fibrosis: A Review of Evidence and Mechanisms.

Zhu, Mingtao; Wang, Yu; Han, Jianwei et al. · 2024 · Antioxidants (Basel, Switzerland) · DOI

Full title: Artesunate Exerts Organ- and Tissue-Protective Effects by Regulating Oxidative Stress, Inflammation, Autophagy, Apoptosis, and Fibrosis: A Review of Evidence and Mechanisms.

Authors: Zhu, Mingtao; Wang, Yu; Han, Jianwei; Sun, Yanping; Wang, Shuang; Yang, Bingyou; Wang, Qiuhong; Kuang, Haixue

Year: 2024

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox13060686

Paper Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.

Zhang, Yongjie; Fan, Tingjun · 2025 · Antioxidants (Basel, Switzerland) · DOI

Full title: Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.

Authors: Zhang, Yongjie; Fan, Tingjun

Year: 2025

Venue: Antioxidants (Basel, Switzerland)

DOI: https://doi.org/10.3390/antiox14111381

Paper Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

Reddy, P. Hemachandra; Oliver, Darryll · 2019 · Cells · DOI

Full title: Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

Authors: Reddy, P. Hemachandra; Oliver, Darryll

Year: 2019

Venue: Cells

DOI: https://doi.org/10.3390/cells8050488

Paper Ketogenic Diet in Alzheimer’s Disease

Rusek, Marta; Pluta, Ryszard; Ułamek-Kozioł, Marzena et al. · 2019 · International Journal of Molecular Sciences · DOI

Full title: Ketogenic Diet in Alzheimer’s Disease

Authors: Rusek, Marta; Pluta, Ryszard; Ułamek-Kozioł, Marzena; Czuczwar, Stanisław J.

Year: 2019

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms20163892

Paper LINC00470 represses cell autophagy and cisplatin sensitivity of glioma via suppressing PTEN expression.

Chen, Biyin; Wang, Wenwu; Lin, Fangfeng et al. · 2023 · Folia neuropathologica · DOI

Full title: LINC00470 represses cell autophagy and cisplatin sensitivity of glioma via suppressing PTEN expression.

Authors: Chen, Biyin; Wang, Wenwu; Lin, Fangfeng; Shi, Shuping; Ou, Shunjie; Yu, Yunqiu

Year: 2023

Venue: Folia neuropathologica

DOI: https://doi.org/10.5114/fn.2023.125327

Thesis The role of PLK2 in modulating alpha-synuclein degradation dynamics in Parkinson's disease

Zhang, Weijian · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The role of PLK2 in modulating alpha-synuclein degradation dynamics in Parkinson's disease

Authors: Zhang, Weijian

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-100408

Thesis A study on the role of p32 in mitophagy

Zhang, Jin · 2017 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: A study on the role of p32 in mitophagy

Authors: Zhang, Jin

Year: 2017

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-104819

Thesis Autophagosome dynamics in Huntington's disease

Li, Chun Hei · 2020 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Autophagosome dynamics in Huntington's disease

Authors: Li, Chun Hei

Year: 2020

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-110546

Thesis Mitochondrial and autophagosomes' transport defect in Q175 knock-in mouse model of huntington's disease

Zhang, Min · 2017 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Mitochondrial and autophagosomes' transport defect in Q175 knock-in mouse model of huntington's disease

Authors: Zhang, Min

Year: 2017

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-105666

Thesis Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Liu, Han-Qing; An, Ya-Wen; Hu, A-Zhen et al. · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Authors: Liu, Han-Qing; An, Ya-Wen; Hu, A-Zhen; Li, Ming-Hua; Wu, Jue-Lian; Liu, Li; Shi, Yu; Cui, Guang-Hui; Chen, Yun

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-95911

Thesis NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson's disease models

Valencia-Alarcón, Eva P.; Duret, Lou C.; Kobayashi, Emi et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson's disease models

Authors: Valencia-Alarcón, Eva P.; Duret, Lou C.; Kobayashi, Emi; Cattaneo, O; Schneider, Bernard L.; Nagoshi, Emi

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/254943

Thesis Tau accumulation in degradative organelles is associated to lysosomal stress

Piovesana, Ester; Magrin, Claudia; Ciccaldo, Matteo et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Tau accumulation in degradative organelles is associated to lysosomal stress

Authors: Piovesana, Ester; Magrin, Claudia; Ciccaldo, Matteo; Sola, Martina; Bellotto, Manolo; Molinari, Maurizio; Papin, Stephanie; Paganetti, Paolo

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/204251

Thesis A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models

Ciccaldo, Matteo; Pérez‐Carmona, Natàlia; Piovesana, Ester et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models

Authors: Ciccaldo, Matteo; Pérez‐Carmona, Natàlia; Piovesana, Ester; Cano-Crespo, Sara; Ruano, Ana; Delgado, Aida; Fregno, Ilaria; Guzmán, Beatriz Calvo‐Flores; Bellotto, Manolo; Molinari, Maurizio; Taylor, Joanne; Papin, Stéphanie; García-Collazo, Ana María; Paganetti, Paolo

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250562

Thesis O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Balana, Aaron T.; Mahul-Mellier, Anne-Laure; Nguyen, Binh A. et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Authors: Balana, Aaron T.; Mahul-Mellier, Anne-Laure; Nguyen, Binh A.; Horvath, Mian; Javed, Afraah; Hard, Eldon R.; Jasiqi, Yllza; Singh, Preeti; Afrin, Shumaila; Pedretti, Rose; Singh, Virender; Lee, Virginia M. -Y.; Luk, Kelvin C.; Saelices, Lorena; Lashuel, Hilal A; Pratt, Matthew R.

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/205548

Thesis Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Oueslati, Abid; Schneider, Bernard L.; Aebischer, Patrick et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Authors: Oueslati, Abid; Schneider, Bernard L.; Aebischer, Patrick; Lashuel, Hilal A.

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/94836

Thesis Measurement of autophagy flux in the nervous system in vivo

Castillo, K.; Valenzuela, V.; Matus, S. et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Measurement of autophagy flux in the nervous system in vivo

Authors: Castillo, K.; Valenzuela, V.; Matus, S.; Nassif, M.; Onate, M.; Fuentealba, Y.; Encina, G.; Irrazabal, T.; Parsons, G.; Court, F. A.; Schneider, B. L.; Armentano, D.; Hetz, C.

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/99328

Thesis GTPase Activity Plays a Key Role in the Pathobiology of LRRK2

Xiong, Yulan; Coombes, Candice E.; Kilaru, Austin et al. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: GTPase Activity Plays a Key Role in the Pathobiology of LRRK2

Authors: Xiong, Yulan; Coombes, Candice E.; Kilaru, Austin; Li, Xiaojie; Gitler, Aaron D.; Bowers, William J.; Dawson, Valina L.; Dawson, Ted M.; Moore, Darren J.

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/75538

Thesis Mechanisms of LRRK2-Mediated Neurodegeneration

Tsika, Elpida; Moore, Darren J. · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mechanisms of LRRK2-Mediated Neurodegeneration

Authors: Tsika, Elpida; Moore, Darren J.

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80762

Thesis PGC-1 alpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein

Ciron, Carine; Zheng, Lu; Bobela, Wojciech et al. · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: PGC-1 alpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein

Authors: Ciron, Carine; Zheng, Lu; Bobela, Wojciech; Knott, Graham W.; Leone, Teresa C.; Kelly, Daniel P.; Schneider, Bernard L.

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/120979

Thesis AUTOPHAGY AND NEURODEGENERATION: DISCOVERING CRITICAL INSIGHTS AND INNOVATIVE THERAPEUTIC STRATEGIES USING A NOVEL HUMAN NEURON MODEL OF BPAN

Zaveri, Hetavi · 2024 · Johns Hopkins University · DOI

Full title: AUTOPHAGY AND NEURODEGENERATION: DISCOVERING CRITICAL INSIGHTS AND INNOVATIVE THERAPEUTIC STRATEGIES USING A NOVEL HUMAN NEURON MODEL OF BPAN

Authors: Zaveri, Hetavi

Year: 2024

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/69818

Thesis The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

de Oliveira, Rita Machado; Vicente Miranda, Hugo; Francelle, Laetitia et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

Authors: de Oliveira, Rita Machado; Vicente Miranda, Hugo; Francelle, Laetitia; Pinho, Raquel; Szegö, Éva M; Martinho, Renato; Munari, Francesca; Lázaro, Diana F; Moniot, Sébastien; Guerreiro, Patrícia; Fonseca, Luis; Marijanovic, Zrinka; Antas, Pedro; Gerhardt, Ellen; Enguita, Francisco Javier; Fauvet, Bruno; Penque, Deborah; Pais, Teresa Faria; Tong, Qiang; Becker, Stefan; Kügler, Sebastian; Lashuel, Hilal; Steegborn, Clemens; Zweckstetter, Markus; Outeiro, Tiago Fleming

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/134993

Thesis An Investigation into Mitigating Proteotoxicity In Vitro and In Vivo

Shrivastava, Gautam Anand · 2018 · Johns Hopkins University · DOI

Full title: An Investigation into Mitigating Proteotoxicity In Vitro and In Vivo

Authors: Shrivastava, Gautam Anand

Year: 2018

Venue: Johns Hopkins University

DOI: http://jhir.library.jhu.edu/handle/1774.2/44605

Thesis Reduction of SOD Aggregation Using In Vitro and In Vivo ALS Models

Shea, John · 2019 · Johns Hopkins University · DOI

Full title: Reduction of SOD Aggregation Using In Vitro and In Vivo ALS Models

Authors: Shea, John

Year: 2019

Venue: Johns Hopkins University

DOI: http://jhir.library.jhu.edu/handle/1774.2/60328

Thesis Novel mechanisms of autophagy-lysosome dysfunction in GBA1 Parkinson disease

Tewari, Shailvi · 2025 · Johns Hopkins University · DOI

Full title: Novel mechanisms of autophagy-lysosome dysfunction in GBA1 Parkinson disease

Authors: Tewari, Shailvi

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70991

Thesis Repurposing proteostasis-modifying drugs to prevent or treat age-related dementia: A systematic review

Heard, DS; Tuttle, CSL; Lautenschlager, NT et al. · 2020 · University of Melbourne · DOI

Full title: Repurposing proteostasis-modifying drugs to prevent or treat age-related dementia: A systematic review

Authors: Heard, DS; Tuttle, CSL; Lautenschlager, NT; Maier, AB

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/253273

Thesis Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

Moujalled, D; White, AR · 2018 · University of Melbourne · DOI

Full title: Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

Authors: Moujalled, D; White, AR

Year: 2018

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/216653

Thesis Natural Products as Promising Drug Candidates for the Treatment of Alzheimer's Disease: Molecular Mechanism Aspect

Ansari, N; Khodagholi, F · 2020 · University of Melbourne · DOI

Full title: Natural Products as Promising Drug Candidates for the Treatment of Alzheimer's Disease: Molecular Mechanism Aspect

Authors: Ansari, N; Khodagholi, F

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/251130

Thesis Trehalose improves traumatic brain injury-induced cognitive impairment

Portbury, SD; Hare, DJ; Finkelstein, DI et al. · 2020 · University of Melbourne · DOI

Full title: Trehalose improves traumatic brain injury-induced cognitive impairment

Authors: Portbury, SD; Hare, DJ; Finkelstein, DI; Adlard, PA

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/254931

Thesis Effects of Resveratrol and Morin on Insoluble Tau in Tau Transgenic Mice.

Yu, KC; Kwan, P; Cheung, SKK et al. · 2020 · University of Melbourne · DOI

Full title: Effects of Resveratrol and Morin on Insoluble Tau in Tau Transgenic Mice.

Authors: Yu, KC; Kwan, P; Cheung, SKK; Ho, A; Baum, L

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/250317

Thesis Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression

Perera, ND; Sheean, RK; Lau, CL et al. · 2020 · University of Melbourne · DOI

Full title: Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression

Authors: Perera, ND; Sheean, RK; Lau, CL; Shin, YS; Beart, PM; Horne, MK; Turner, BJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/257156

Thesis Molecular mechanisms of cell death in neurological diseases

Moujalled, D; Strasser, A; Liddell, JR · 2021 · University of Melbourne · DOI

Full title: Molecular mechanisms of cell death in neurological diseases

Authors: Moujalled, D; Strasser, A; Liddell, JR

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/280998

Thesis Iron promotes the clearance of α-synuclein: An Editorial for 'H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity” on page 177

Tuo, QZ; Lei, P · 2021 · University of Melbourne · DOI

Full title: Iron promotes the clearance of α-synuclein: An Editorial for 'H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity” on page 177

Authors: Tuo, QZ; Lei, P

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/276111

Thesis The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Fox, JH; Connor, T; Chopra, V et al. · 2021 · University of Melbourne · DOI

Full title: The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Authors: Fox, JH; Connor, T; Chopra, V; Dorsey, K; Kama, JA; Bleckmann, D; Betschart, C; Hoyer, D; Frentzel, S; Difiglia, M; Paganetti, P; Hersch, SM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/264755

Thesis Inhibition of bioenergetics provides novel insights into recruitment of PINK1-dependent neuronal mitophagy

Shin, YS; Ryall, JG; Britto, JM et al. · 2021 · University of Melbourne · DOI

Full title: Inhibition of bioenergetics provides novel insights into recruitment of PINK1-dependent neuronal mitophagy

Authors: Shin, YS; Ryall, JG; Britto, JM; Lau, CL; Devenish, RJ; Nagley, P; Beart, PM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/285442

Thesis Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Corti, O; Blomgren, K; Poletti, A et al. · 2021 · University of Melbourne · DOI

Full title: Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Authors: Corti, O; Blomgren, K; Poletti, A; Beart, PM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/274135

Thesis Étude de l’effet neuro-protecteur de polyphénols issus de la Pomme-Grenade ainsi que de leurs dérivés métaboliques

Bretonneau, Constantin · 2022 · Université de Montréal (Papyrus) · DOI

Full title: Étude de l’effet neuro-protecteur de polyphénols issus de la Pomme-Grenade ainsi que de leurs dérivés métaboliques

Authors: Bretonneau, Constantin

Year: 2022

Venue: Université de Montréal (Papyrus)

DOI: http://hdl.handle.net/1866/26205

Thesis Autophagic activity in neuronal cell death.

Button, Robert W; Luo, Shouqing; Rubinsztein, David C · 2015 · University of Cambridge · DOI

Full title: Autophagic activity in neuronal cell death.

Authors: Button, Robert W; Luo, Shouqing; Rubinsztein, David C

Year: 2015

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/248524

Thesis Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Underwood, Benjamin R; Imarisio, Sara; Fleming, Angeleen et al. · 2018 · University of Cambridge · DOI

Full title: Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Authors: Underwood, Benjamin R; Imarisio, Sara; Fleming, Angeleen; Rose, Claudia; Krishna, Gauri; Heard, Phoebe; Quick, Marie; Korolchuk, Viktor I; Renna, Maurizio; Sarkar, Sovan; García-Arencibia, Moisés; O'Kane, Cahir J; Murphy, Michael P; Rubinsztein, David C

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/270325

Thesis Autophagy and neurodegeneration

Frake, Rebecca A; Ricketts, Thomas; Menzies, Fiona M et al. · 2015 · University of Cambridge · DOI

Full title: Autophagy and neurodegeneration

Authors: Frake, Rebecca A; Ricketts, Thomas; Menzies, Fiona M; Rubinsztein, David C

Year: 2015

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/252949

Thesis Decanoato de nandrolona e AMPK modulam a macroautofagia e bioenergética cerebral no envelhecimento

Strogulski, Nathan Ryzewski · 2019 · Universidade Federal do Rio Grande do Sul – LUME · DOI

Full title: Decanoato de nandrolona e AMPK modulam a macroautofagia e bioenergética cerebral no envelhecimento

Authors: Strogulski, Nathan Ryzewski

Year: 2019

Venue: Universidade Federal do Rio Grande do Sul – LUME

DOI: http://hdl.handle.net/10183/193629

Thesis Zebrafish as a model to understand autophagy and its role in neurological disease.

Fleming, Angeleen; Rubinsztein, David C · 2018 · University of Cambridge · DOI

Full title: Zebrafish as a model to understand autophagy and its role in neurological disease.

Authors: Fleming, Angeleen; Rubinsztein, David C

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/270333

Thesis Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.

Willén, Katarina; Edgar, James R; Hasegawa, Takafumi et al. · 2017 · University of Cambridge · DOI

Full title: Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.

Authors: Willén, Katarina; Edgar, James R; Hasegawa, Takafumi; Tanaka, Nobuyuki; Futter, Clare E; Gouras, Gunnar K

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/270155

Thesis Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

Menzies, FM; Garcia-Arencibia, M; Imarisio, S et al. · 2014 · University of Cambridge · DOI

Full title: Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

Authors: Menzies, FM; Garcia-Arencibia, M; Imarisio, S; O'Sullivan, NC; Ricketts, T; Kent, BA; Rao, MV; Lam, W; Green-Thompson, ZW; Nixon, RA; Saksida, LM; Bussey, TJ; O'Kane, CJ; Rubinsztein, DC

Year: 2014

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/246151

Thesis A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A; Schlotawa, L; Fleming, A et al. · 2017 · University of Cambridge · DOI

Full title: A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Authors: Lopez, A; Schlotawa, L; Fleming, A; Rubinsztein, DC

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/262885

Thesis Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.

Hung, Christy OY; Livesey, Frederick J · 2019 · University of Cambridge · DOI

Full title: Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.

Authors: Hung, Christy OY; Livesey, Frederick J

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/287623

Thesis Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy.

Nehammer, Camilla; Ejlerskov, Patrick; Gopal, Sandeep et al. · 2019 · University of Cambridge · DOI

Full title: Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy.

Authors: Nehammer, Camilla; Ejlerskov, Patrick; Gopal, Sandeep; Handley, Ava; Ng, Leelee; Moreira, Pedro; Lee, Huikyong; Issazadeh-Navikas, Shohreh; Rubinsztein, David C; Pocock, Roger

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/299676

Thesis Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.

Kruppa, Antonina J; Ott, Stanislav; Chandraratna, Dhia S et al. · 2018 · University of Cambridge · DOI

Full title: Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.

Authors: Kruppa, Antonina J; Ott, Stanislav; Chandraratna, Dhia S; Irving, James A; Page, Richard M; Speretta, Elena; Seto, Tiffany; Camargo, Luiz Miguel; Marciniak, Stefan J; Lomas, David A; Crowther, Damian C

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/275918

Thesis Prions: generation and spread versus neurotoxicity.

Halliday, Mark; Radford, Helois; Mallucci, Giovanna R · 2019 · University of Cambridge · DOI

Full title: Prions: generation and spread versus neurotoxicity.

Authors: Halliday, Mark; Radford, Helois; Mallucci, Giovanna R

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/294751

Thesis Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases.

Ejlerskov, Patrick; Ashkenazi, Avraham; Rubinsztein, David C · 2018 · University of Cambridge · DOI

Full title: Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases.

Authors: Ejlerskov, Patrick; Ashkenazi, Avraham; Rubinsztein, David C

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/277634

Thesis Autophagy in Childhood Neurological Disorders

Rubinsztein, DC; Zhu, Ye; Runwal, Gautam et al. · 2018 · University of Cambridge · DOI

Full title: Autophagy in Childhood Neurological Disorders

Authors: Rubinsztein, DC; Zhu, Ye; Runwal, Gautam; Obrocki, Pawel

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/286379

Thesis Autophagy in Neuronal Development and Plasticity.

Fleming, Angeleen; Rubinsztein, David C · 2020 · University of Cambridge · DOI

Full title: Autophagy in Neuronal Development and Plasticity.

Authors: Fleming, Angeleen; Rubinsztein, David C

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/307968

Thesis Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases.

Djajadikerta, Alvin; Keshri, Swati; Pavel, Mariana et al. · 2019 · University of Cambridge · DOI

Full title: Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases.

Authors: Djajadikerta, Alvin; Keshri, Swati; Pavel, Mariana; Prestil, Ryan; Ryan, Laura; Rubinsztein, David C

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/299796

Thesis Mendelian neurodegenerative disease genes involved in autophagy

Stamatakou, Eleanna; Wróbel, Lidia; Hill, Sandra Malmgren et al. · 2020 · University of Cambridge · DOI

Full title: Mendelian neurodegenerative disease genes involved in autophagy

Authors: Stamatakou, Eleanna; Wróbel, Lidia; Hill, Sandra Malmgren; Puri, Claudia; Son, Sung Min; Fujimaki, Motoki; Zhu, Ye; Siddiqi, Farah; Fernandez-Estevez, Marian; Manni, Marco M.; Park, So Jung; Villeneuve, Julien; Rubinsztein, David Chaim

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/306793

Thesis Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease.

Thackray, Alana M; Lam, Brian; Shahira Binti Ab Razak, Anisa et al. · 2020 · University of Cambridge · DOI

Full title: Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease.

Authors: Thackray, Alana M; Lam, Brian; Shahira Binti Ab Razak, Anisa; Yeo, Giles; Bujdoso, Raymond

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/304498

Thesis Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

Szebényi, Kornélia; Wenger, Léa MD; Sun, Yu et al. · 2021 · University of Cambridge · DOI

Full title: Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

Authors: Szebényi, Kornélia; Wenger, Léa MD; Sun, Yu; Dunn, Alexander WE; Limegrover, Colleen A; Gibbons, George M; Conci, Elena; Paulsen, Ole; Mierau, Susanna B; Balmus, Gabriel; Lakatos, András

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/327125

Thesis The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy.

Festa, Beatrice Paola; Barbosa, Antonio Daniel; Rob, Matea et al. · 2021 · University of Cambridge · DOI

Full title: The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy.

Authors: Festa, Beatrice Paola; Barbosa, Antonio Daniel; Rob, Matea; Rubinsztein, David C

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/325343

Thesis Huntingtin-lowering strategies for Huntington's disease.

Barker, Roger A; Fujimaki, Motoki; Rogers, Priya et al. · 2020 · University of Cambridge · DOI

Full title: Huntingtin-lowering strategies for Huntington's disease.

Authors: Barker, Roger A; Fujimaki, Motoki; Rogers, Priya; Rubinsztein, David C

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/308624

Thesis Gene and Cell-Based Therapies for Parkinson’s Disease: Where Are We?

Buttery, Philip C.; Barker, Roger A. · 2021 · University of Cambridge · DOI

Full title: Gene and Cell-Based Therapies for Parkinson’s Disease: Where Are We?

Authors: Buttery, Philip C.; Barker, Roger A.

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/317024

Thesis L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.

Castejón-Vega, Beatriz; Rubio, Alejandro; Pérez-Pulido, Antonio J et al. · 2022 · University of Cambridge · DOI

Full title: L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.

Authors: Castejón-Vega, Beatriz; Rubio, Alejandro; Pérez-Pulido, Antonio J; Quiles, José L; Lane, Jon D; Fernández-Domínguez, Beatriz; Cachón-González, María Begoña; Martín-Ruiz, Carmen; Sanz, Alberto; Cox, Timothy M; Alcocer-Gómez, Elísabet; Cordero, Mario D

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/332448

Thesis Breakthroughs and bottlenecks in autophagy research.

Mizushima, Noboru; White, Eileen; Rubinsztein, David C · 2021 · University of Cambridge · DOI

Full title: Breakthroughs and bottlenecks in autophagy research.

Authors: Mizushima, Noboru; White, Eileen; Rubinsztein, David C

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/325128

Thesis Vinexin contributes to autophagic decline in brain ageing across species

Rubinsztein, David; Park, So Jung; Frake, Rebecca et al. · 2022 · University of Cambridge · DOI

Full title: Vinexin contributes to autophagic decline in brain ageing across species

Authors: Rubinsztein, David; Park, So Jung; Frake, Rebecca; Karabiyik, Cansu; Son, Sung Min; Siddiqi, Farah; Bento, Carla; Sterk, Peter; Vicinanza, Mariella

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/336109

Thesis Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

Runfola, Massimiliano; Perni, Michele; Yang, Xiaoting et al. · 2022 · University of Cambridge · DOI

Full title: Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

Authors: Runfola, Massimiliano; Perni, Michele; Yang, Xiaoting; Marchese, Maria; Bacci, Andrea; Mero, Serena; Santorelli, Filippo M; Polini, Beatrice; Chiellini, Grazia; Giuliani, Daniela; Vilella, Antonietta; Bodria, Martina; Daini, Eleonora; Vandini, Eleonora; Rudge, Simon; Gul, Sheraz; Wakelam, Michale OJ; Vendruscolo, Michele; Rapposelli, Simona

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/332059

Thesis SMER28 binding to VCP/p97 enhances both autophagic and proteasomal neurotoxic protein clearance.

Wrobel, Lidia; Hill, Sandra M; Rubinsztein, David C · 2022 · University of Cambridge · DOI

Full title: SMER28 binding to VCP/p97 enhances both autophagic and proteasomal neurotoxic protein clearance.

Authors: Wrobel, Lidia; Hill, Sandra M; Rubinsztein, David C

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/340353

Thesis A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo

Lopez, Ana; Gorb, Alena; Palha, Nuno et al. · 2022 · University of Cambridge · DOI

Full title: A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo

Authors: Lopez, Ana; Gorb, Alena; Palha, Nuno; Fleming, Angeleen; Rubinsztein, David

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/337164

Thesis Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling.

Park, So Jung; Frake, Rebecca A; Rubinsztein, David C · 2022 · University of Cambridge · DOI

Full title: Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling.

Authors: Park, So Jung; Frake, Rebecca A; Rubinsztein, David C

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/339011

Thesis USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Mauri, Sofia; Bernardo, Greta; Martinez, Aitor et al. · 2023 · University of Cambridge · DOI

Full title: USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Authors: Mauri, Sofia; Bernardo, Greta; Martinez, Aitor; Favaro, Mariavittoria; Trevisan, Marta; Cobraiville, Gael; Fillet, Marianne; Caicci, Federico; Whitworth, Alexander J; Ziviani, Elena

Year: 2023

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/350221

Thesis Trial to assess the tolerability of using felodipine to upregulate autophagy as a treatment of Huntington’s disease (FELL-HD): a phase II, single-centre, open-label, dose-finding trial protocol

Andresen, Katie; Cutting, Emma; Apostolopoulos, Dimitrios et al. · 2024 · University of Cambridge · DOI

Full title: Trial to assess the tolerability of using felodipine to upregulate autophagy as a treatment of Huntington’s disease (FELL-HD): a phase II, single-centre, open-label, dose-finding trial protocol

Authors: Andresen, Katie; Cutting, Emma; Apostolopoulos, Dimitrios; Evans, Amy H; Oakley, Laura; Dayimu, Alimu; Demiris, Nikolaos; Bongaerts, Katherine; Staples, Robyn; Gooding, Wendy; Rubinsztein, David; Barker, Roger A

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/373052

Thesis The autophagy of stress granules.

Ryan, Laura; Rubinsztein, David C · 2023 · University of Cambridge · DOI

Full title: The autophagy of stress granules.

Authors: Ryan, Laura; Rubinsztein, David C

Year: 2023

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/360939

Thesis How does autophagy impact neurological function?

Fleming, Angeleen; Lopez, Ana; Rob, Matea et al. · 2025 · University of Cambridge · DOI

Full title: How does autophagy impact neurological function?

Authors: Fleming, Angeleen; Lopez, Ana; Rob, Matea; Ramakrishna, Sarayu; Park, So Jung; Li, Xinyi; Rubinsztein, David C

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/384309

Thesis Targeting Protein Aggregation in ALS.

Perni, Michele; Mannini, Benedetta · 2024 · University of Cambridge · DOI

Full title: Targeting Protein Aggregation in ALS.

Authors: Perni, Michele; Mannini, Benedetta

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/375930

Thesis A53T alpha-synuclein induces mitophagy through MAM-induced fission and reduced impairment of LC3B to promote alpha-synuclein degradation

Humphries, Kayla · 2017 · University of Guelph · DOI

Full title: A53T alpha-synuclein induces mitophagy through MAM-induced fission and reduced impairment of LC3B to promote alpha-synuclein degradation

Authors: Humphries, Kayla

Year: 2017

Venue: University of Guelph

DOI: http://hdl.handle.net/10214/12113

Thesis Investigating The Role Of LC3B In The Seeding Of Alpha-synuclein In Parkinson’s Disease Model Systems

Porte-Trachsel, Natalie · 2023 · University of Guelph · DOI

Full title: Investigating The Role Of LC3B In The Seeding Of Alpha-synuclein In Parkinson’s Disease Model Systems

Authors: Porte-Trachsel, Natalie

Year: 2023

Venue: University of Guelph

DOI: https://hdl.handle.net/10214/27355

Thesis RATIONAL DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETED AGAINST NEURODEGENERATIVE PROCESSES AND DISEASES

GORNATI, DAVIDE · 2019 · Università degli Studi di Milano (AIR) · DOI

Full title: RATIONAL DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETED AGAINST NEURODEGENERATIVE PROCESSES AND DISEASES

Authors: GORNATI, DAVIDE

Year: 2019

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/606993

Thesis Autophagy enhancement as a target for mood stabilizing drugs.

Poquette, Chelsey Hannah · 2011 · University of Minnesota - Digital Conservancy · DOI

Full title: Autophagy enhancement as a target for mood stabilizing drugs.

Authors: Poquette, Chelsey Hannah

Year: 2011

Venue: University of Minnesota - Digital Conservancy

DOI: http://purl.umn.edu/102458

Thesis Spermidine Protects Mitochondria Against Amyloid-β Oligomers

Mosca, Drake · 2025 · University of Guelph · DOI

Full title: Spermidine Protects Mitochondria Against Amyloid-β Oligomers

Authors: Mosca, Drake

Year: 2025

Venue: University of Guelph

DOI: https://hdl.handle.net/10214/28800

Thesis A Drug Cocktail of Rapamycin, Acarbose, and Phenylbutyrate Enhances Resilience to an Early-Stage Model of Alzheimer’s Disease

Wezeman, Jackson · 2024 · University of Washington - ResearchWorks · DOI

Full title: A Drug Cocktail of Rapamycin, Acarbose, and Phenylbutyrate Enhances Resilience to an Early-Stage Model of Alzheimer’s Disease

Authors: Wezeman, Jackson

Year: 2024

Venue: University of Washington - ResearchWorks

DOI: http://hdl.handle.net/1773/51069

Thesis Autophagy, or not to be: The delicate balance of cellular self-digestion in neurons and neurodegeneration

Lassen, Amy Denise · 2013 · University of Washington - ResearchWorks · DOI

Full title: Autophagy, or not to be: The delicate balance of cellular self-digestion in neurons and neurodegeneration

Authors: Lassen, Amy Denise

Year: 2013

Venue: University of Washington - ResearchWorks

DOI: http://hdl.handle.net/1773/22428

Thesis Chaperone-mediated autophagy : roles in disease and aging

Cuervo, Ana Maria; Wong, Esther · 2015 · Nanyang Technological University (NTU) · DOI

Full title: Chaperone-mediated autophagy : roles in disease and aging

Authors: Cuervo, Ana Maria; Wong, Esther

Year: 2015

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/103863

Thesis Molecular Strategies to Target Protein Aggregation in Huntington's Disease

Jarosińska, Olga D; Rüdiger, Stefan G D · 2021 · Utrecht University · DOI

Full title: Molecular Strategies to Target Protein Aggregation in Huntington's Disease

Authors: Jarosińska, Olga D; Rüdiger, Stefan G D

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/425192

Thesis Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Burk, Katja; Pasterkamp, R. Jeroen · 2019 · Utrecht University · DOI

Full title: Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Authors: Burk, Katja; Pasterkamp, R. Jeroen

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/391830

Thesis Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Esselens, C.; Oorschot, V.; Baert, V. et al. · 2004 · Utrecht University · DOI

Full title: Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Authors: Esselens, C.; Oorschot, V.; Baert, V.; Raemaekers, T.; Spittaels, K.; Serneels, L.; Zheng, H.; Saftig, P.; Strooper, B. de; Klumperman, J.; Annaert, W.

Year: 2004

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/12363

Thesis Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS

Salomon-Zimri, Shiran; Pushett, Avital; Russek-Blum, Niva et al. · 2023 · Utrecht University · DOI

Full title: Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS

Authors: Salomon-Zimri, Shiran; Pushett, Avital; Russek-Blum, Niva; Van Eijk, Ruben P.A.; Birman, Nurit; Abramovich, Beatrice; Eitan, Erez; Elgrart, Katya; Beaulieu, Danielle; Ennist, David L.; Berry, James D.; Paganoni, Sabrina; Shefner, Jeremy M.; Drory, Vivian E.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/455596

Thesis Probing aggrephagy using chemically-induced protein aggregates

Janssen, Anne F J; Katrukha, Eugene A; van Straaten, Wendy et al. · 2018 · Utrecht University · DOI

Full title: Probing aggrephagy using chemically-induced protein aggregates

Authors: Janssen, Anne F J; Katrukha, Eugene A; van Straaten, Wendy; Verlhac, Pauline; Reggiori, Fulvio; Kapitein, Lukas C

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/376052

Thesis Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Authors: Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor; Pereira de Almeida, Luís; Cavadas, Cláudia; Guarente, Leonard Pershing

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/106599

Thesis Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Kuo, Szu-Yu; Castoreno, Adam B.; Aldrich, Leslie N. et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Authors: Kuo, Szu-Yu; Castoreno, Adam B.; Aldrich, Leslie N.; Lassen, Kara G.; Goel, Gautam; Dancik, Vlado; Kuballa, Petric; Latorre, Isabel; Conway, Kara L.; Sarkar, Sovan; Maetzel, Dorothea; Jaenisch, Rudolf; Clemons, Paul A.; Schreiber, Stuart L.; Shamji, Alykhan F.; Xavier, Ramnik J.

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/101110

Thesis How do protein aggregates escape quality control in neurodegeneration?

Koopman, Margreet B.; Ferrari, Luca; Rüdiger, Stefan G.D. · 2022 · Utrecht University · DOI

Full title: How do protein aggregates escape quality control in neurodegeneration?

Authors: Koopman, Margreet B.; Ferrari, Luca; Rüdiger, Stefan G.D.

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426498

Thesis S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

Authors: Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph; Dolatabadi, Nima; Soldner, Frank; McClatchy, Daniel B.; Diedrich, Jolene K.; Ambasudhan, Rajesh; Nakamura, Tomohiro; Jaenisch, Rudolf; Lipton, Stuart A.; Yates, John R., III

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/117502

Thesis A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Graeff, Johannes; Kahn, Martin; Samiei, Alireza et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Authors: Graeff, Johannes; Kahn, Martin; Samiei, Alireza; Gao, Jun; Ota, Kristie; Rei, Damien; Tsai, Li-Huei

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/112704

Thesis IKKβ slows Huntington’s disease progression in R6/1 mice

Ochaba, Joseph; Fote, Gianna; Kachemov, Marketta et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: IKKβ slows Huntington’s disease progression in R6/1 mice

Authors: Ochaba, Joseph; Fote, Gianna; Kachemov, Marketta; Thein, Soe; Yeung, Sylvia Y.; Lau, Alice L.; Hernandez, Sarah; Lim, Ryan G.; Casale, Malcolm; Neel, Michael J.; Monuki, Edwin S.; Reidling, Jack; Housman, David E; Thompson, Leslie M.; Steffan, Joan S.

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/126076

Thesis Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Tardiff, Daniel F.; Lindquist, Susan · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Authors: Tardiff, Daniel F.; Lindquist, Susan

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/101272

Thesis Development and Screening of Contrast Agents for In Vivo Imaging of Parkinson’s Disease

Neal, Krista L.; Shakerdge, Naomi B.; Hou, Steven S. et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Development and Screening of Contrast Agents for In Vivo Imaging of Parkinson’s Disease

Authors: Neal, Krista L.; Shakerdge, Naomi B.; Hou, Steven S.; Klunk, William E.; Mathis, Chester A.; McLean, Pamela J.; Bacskai, Brian J.; Nesterov, Evgueni; Swager, Timothy M

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/104658

Thesis Genome-wide genetic screening in the mammalian CNS

Wertz, Mary H.; Heiman, Myriam · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Genome-wide genetic screening in the mammalian CNS

Authors: Wertz, Mary H.; Heiman, Myriam

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/124812

Thesis Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease

Sarkar, Sovan; Carroll, Bernadette; Buganim, Yosef et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease

Authors: Sarkar, Sovan; Carroll, Bernadette; Buganim, Yosef; Maetzel, Dorothea; Ng, Alex H. M.; Cassady, John P.; Cohen, Malkiel A.; Chakraborty, Souvik; Wang, Haoyi; Spooner, Eric; Ploegh, Hidde; Gsponer, Joerg; Korolchuk, Viktor I.; Jaenisch, Rudolf

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/90306

Thesis Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

Treat, Lisa H.; Raymond, Scott Bruce; Bacskai, Brian J. et al. · 2010 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

Authors: Treat, Lisa H.; Raymond, Scott Bruce; Bacskai, Brian J.; Hynynen, Kullervo; McDannold, Nathan J.; Dewey, Jonathan D.

Year: 2010

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/55365

Thesis High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Wu, Chaohong; Hong, Pengyu; Schulte, Joost et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Authors: Wu, Chaohong; Hong, Pengyu; Schulte, Joost; Sepp, Katharine J.; Littleton, J. Troy

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/69109

Thesis Modelling Neurodegeneration in Saccharomyces Cerevisiae: Why Cook with Baker's Yeast?

Khurana, Vikram; Lindquist, Susan · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Modelling Neurodegeneration in Saccharomyces Cerevisiae: Why Cook with Baker's Yeast?

Authors: Khurana, Vikram; Lindquist, Susan

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/69914

Thesis Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol

Svensson, Jonas E.; Bolin, Martin; Thor, Daniel et al. · 2024 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol

Authors: Svensson, Jonas E.; Bolin, Martin; Thor, Daniel; Williams, Pete A.; Brautaset, Rune; Carlsson, Marcus; Sörensson, Peder; Marlevi, David; Spin-Neto, Rubens; Probst, Monika; Hagman, Göran; Morén, Anton Forsberg; Kivipelto, Miia; Plavén-Sigray, Pontus

Year: 2024

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/154090

Thesis Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

Wertz, Mary H; Mitchem, Mollie R; Pineda, S Sebastian et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

Authors: Wertz, Mary H; Mitchem, Mollie R; Pineda, S Sebastian; Hachigian, Lea J; Lee, Hyeseung; Lau, Vanessa; Powers, Alex; Kulicke, Ruth; Madan, Gurrein K; Colic, Medina; Therrien, Martine; Vernon, Amanda; Beja-Glasser, Victoria F; Hegde, Mudra; Gao, Fan; Kellis, Manolis; Hart, Traver; Doench, John G; Heiman, Myriam

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/136278

Thesis Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, Joseph; Csikos, George; Zheng, Shuqiu et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Potential function for the Huntingtin protein as a scaffold for selective autophagy

Authors: Ochaba, Joseph; Csikos, George; Zheng, Shuqiu; Margulis, Julia; Salazar, Lisa; Mao, Kai; Lau, Alice L.; Yeung, Sylvia Y.; Humbert, Sandrine; Klionsky, Daniel J.; Finkbeiner, Steven; Zeitlin, Scott O.; Marsh, J. Lawrence; Thompson, Leslie M.; Steffan, Joan S.; Lukacsovich, Tamas; Saudou, Frederic; Housman, David E

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/97246

Thesis NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

· 2024 · Massachusetts Institute of Technology (MIT) · DOI

Full title: NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

Year: 2024

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/156897

Thesis SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

Donmez Yalcin, Gizem; Arun, Anirudh; Chung, Chee Yeun et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

Authors: Donmez Yalcin, Gizem; Arun, Anirudh; Chung, Chee Yeun; McLean, Pamela J.; Lindquist, Susan; Guarente, Leonard Pershing

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/72526

Thesis Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

Maetzel, Dorothea; Sarkar, Sovan; Wang, Haoyi et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

Authors: Maetzel, Dorothea; Sarkar, Sovan; Wang, Haoyi; Abi-Mosleh, Lina; Xu, Ping; Gao, Qing; Mitalipova, Maisam; Jaenisch, Rudolf; Cheng, Albert Wu

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96366

Thesis Wallerian Degeneration Slow mutation does not alter the amyloid pathology of Alzheimer's disease

Shih, Ann Yu-Jung · 2008 · University of California, San Diego (UCSD) · DOI

Full title: Wallerian Degeneration Slow mutation does not alter the amyloid pathology of Alzheimer's disease

Authors: Shih, Ann Yu-Jung

Year: 2008

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0pq0c761

Thesis Function of Protein Kinase RNA-like Endoplasmic Reticulum Kinase in regulating tau protein aggregation in Alzheimer’s Disease and Progressive Supranuclear Palsy

Xu, Ke · 2021 · University of California, San Diego (UCSD) · DOI

Full title: Function of Protein Kinase RNA-like Endoplasmic Reticulum Kinase in regulating tau protein aggregation in Alzheimer’s Disease and Progressive Supranuclear Palsy

Authors: Xu, Ke

Year: 2021

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0ng89469

Thesis Lysosomal Leakage of Cathepsin B in Alzheimer's Disease and Related Neurodegenerative Brain Disorders

Ito, Gen · 2021 · University of California, San Diego (UCSD) · DOI

Full title: Lysosomal Leakage of Cathepsin B in Alzheimer's Disease and Related Neurodegenerative Brain Disorders

Authors: Ito, Gen

Year: 2021

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/4hr292c1

Thesis Identification of cellular mechanisms that control α-synuclein aggregation using a genome-wide CRISPR-based functional genomics screen

See, Stephanie Kum-Yin · 2020 · University of California, San Francisco (UCSF) · DOI

Full title: Identification of cellular mechanisms that control α-synuclein aggregation using a genome-wide CRISPR-based functional genomics screen

Authors: See, Stephanie Kum-Yin

Year: 2020

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/627856jm

Thesis Elucidating the role of autophagy in the clearance of phosphorylated tau protein in human neurons

Lotfy, Peter · 2016 · University of California, San Diego (UCSD) · DOI

Full title: Elucidating the role of autophagy in the clearance of phosphorylated tau protein in human neurons

Authors: Lotfy, Peter

Year: 2016

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/854345k3

Thesis Elucidating the Relationship Between NPC1 Mutations and Autophagy Dysregulation Using CRISPR-engineered Human Neurons

Wu, Emma · 2019 · University of California, San Diego (UCSD) · DOI

Full title: Elucidating the Relationship Between NPC1 Mutations and Autophagy Dysregulation Using CRISPR-engineered Human Neurons

Authors: Wu, Emma

Year: 2019

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/7ct9h80c

Thesis The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer disease

Zhi Tang (18687184) · 2014 · Karolinska Institutet · DOI

Full title: The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer disease

Authors: Zhi Tang (18687184)

Year: 2014

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26906134

Thesis Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

Rasmus Berglund (18656620); Andre Ortlieb Guerreiro-Cacais (19851711); Milena Z Adzemovic (15444038) et al. · 2020 · Karolinska Institutet · DOI

Full title: Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

Authors: Rasmus Berglund (18656620); Andre Ortlieb Guerreiro-Cacais (19851711); Milena Z Adzemovic (15444038); Manuel Zeitelhofer (18663373); Harald Lund (18685300); Ewoud Ewing (18653557); Sabrina Ruhrmann (352976); Erik Nutma (12016584); Roham Parsa (492420); Melanie Thessen-Hedreul (19851714); Sandra Amor (506326); Robert Harris (18685297); Tomas Olsson (18688204); Maja Jagodic (18664180)

Year: 2020

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/27233955

Thesis Insulin and autophagy in neurodegeneration

Kawamoto, Elisa Mitiko · 2019 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Insulin and autophagy in neurodegeneration

Authors: Kawamoto, Elisa Mitiko

Year: 2019

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.3389/fnins.2019.00491

Thesis Autophagy modulation for organelle-targeting therapy

Martins, Waleska Kerllen · 2016 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Autophagy modulation for organelle-targeting therapy

Authors: Martins, Waleska Kerllen

Year: 2016

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.5772/63976

Thesis Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions?: a systematic review

Tabnjh, Abedelmalek Kalefh · 2025 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions?: a systematic review

Authors: Tabnjh, Abedelmalek Kalefh

Year: 2025

Venue: Universidade de São Paulo – USP Digital Library

DOI: http://dx.doi.org/10.3389/fncel.2025.1624500

Thesis Effects of physical exercise on autophagy and apoptosis in aged brain: human and animal studies

Kawamoto, Elisa Mitiko · 2020 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Effects of physical exercise on autophagy and apoptosis in aged brain: human and animal studies

Authors: Kawamoto, Elisa Mitiko

Year: 2020

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.3389/fnut.2020.00094

Thesis MOLECULAR MECHANISMS AND THERAPEUTIC APPROACHES IN MN DISEASES

MERONI, MARCO · 2019 · Università degli Studi di Milano (AIR) · DOI

Full title: MOLECULAR MECHANISMS AND THERAPEUTIC APPROACHES IN MN DISEASES

Authors: MERONI, MARCO

Year: 2019

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/608781

Thesis AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES

CASIRAGHI, VALERIA · 2024 · Università degli Studi di Milano (AIR) · DOI

Full title: AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES

Authors: CASIRAGHI, VALERIA

Year: 2024

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1047008

Thesis IMPACT OF LRRK2 KINASE ACTIVITY AT THE PRE-SYNAPTIC SITE: EARLY AND LATE EFFECTS ON PARKINSON'S DISEASE

M.D. Cirnaru · 2016 · Università degli Studi di Milano (AIR) · DOI

Full title: IMPACT OF LRRK2 KINASE ACTIVITY AT THE PRE-SYNAPTIC SITE: EARLY AND LATE EFFECTS ON PARKINSON'S DISEASE

Authors: M.D. Cirnaru

Year: 2016

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/353078

Thesis ASSESSING THE PATHOGENESIS OF MULTIPLE SYSTEM ATROPHY THROUGH CELLULAR MODELS

G. MONZIO COMPAGNONI · 2018 · Università degli Studi di Milano (AIR) · DOI

Full title: ASSESSING THE PATHOGENESIS OF MULTIPLE SYSTEM ATROPHY THROUGH CELLULAR MODELS

Authors: G. MONZIO COMPAGNONI

Year: 2018

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/540359

Thesis VALOSIN CONTAINING PROTEIN IN AMYOTROPHIC LATERAL SCLEROSIS: NEW INSIGHT IN PATHOLOGICAL MECHANISMS

FERRARI, VERONICA · 2020 · Università degli Studi di Milano (AIR) · DOI

Full title: VALOSIN CONTAINING PROTEIN IN AMYOTROPHIC LATERAL SCLEROSIS: NEW INSIGHT IN PATHOLOGICAL MECHANISMS

Authors: FERRARI, VERONICA

Year: 2020

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/752322

Thesis Discovery of Small-Molecule Autophagy Modulators in Mammalian Systems

Kuo, Szu-Yu · 2017 · Harvard University - DASH · DOI

Full title: Discovery of Small-Molecule Autophagy Modulators in Mammalian Systems

Authors: Kuo, Szu-Yu

Year: 2017

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33840641

Thesis Investigation into the effects and mechanisms of rapamycin treatment in two mouse models of Complex I-deficient neurological pathology

Yanos, Melana · 2014 · University of Washington - ResearchWorks · DOI

Full title: Investigation into the effects and mechanisms of rapamycin treatment in two mouse models of Complex I-deficient neurological pathology

Authors: Yanos, Melana

Year: 2014

Venue: University of Washington - ResearchWorks

DOI: http://hdl.handle.net/1773/26136

Thesis TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons

Hao, Jin · 2022 · Harvard University - DASH · DOI

Full title: TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons

Authors: Hao, Jin

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371944

Thesis Alpha-Synuclein Oligomers : Cellular Mechanisms and Aspects of Antibody Treatment

Gustafsson, Gabriel · 2017 · Uppsala University · DOI

Full title: Alpha-Synuclein Oligomers : Cellular Mechanisms and Aspects of Antibody Treatment

Authors: Gustafsson, Gabriel

Year: 2017

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-326320

Thesis The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

Rostami, Jinar · 2020 · Uppsala University · DOI

Full title: The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

Authors: Rostami, Jinar

Year: 2020

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-425971

Thesis mTOR at the nexus of nutrition, growth, ageing and disease

Liu, Grace Y; Sabatini, David M · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: mTOR at the nexus of nutrition, growth, ageing and disease

Authors: Liu, Grace Y; Sabatini, David M

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/136262

Thesis The role of SQSTM1/P62 in axonal development and degeneration in an ALS-FTLD context

Young, Matthew J. · 2020 · University of Nottingham · DOI

Full title: The role of SQSTM1/P62 in axonal development and degeneration in an ALS-FTLD context

Authors: Young, Matthew J.

Year: 2020

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/61004/1/M%20J%20Young%20stxmjy%20Thesis%20CORRECTED%20June%202020.pdf

Thesis Blood-brain barrier functions and their impact on pharmacotherapy and pathogenesis of CNS disorders: novel in vitro and translational in vivo studies in animal models

Gericke, Birthe · 2024 · University of Veterinary Medicine Hannover (TiHo) · DOI

Full title: Blood-brain barrier functions and their impact on pharmacotherapy and pathogenesis of CNS disorders: novel in vitro and translational in vivo studies in animal models

Authors: Gericke, Birthe

Year: 2024

Venue: University of Veterinary Medicine Hannover (TiHo)

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-h-3145

Thesis Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)

Foggin, Sophie · 2022 · University of Nottingham · DOI

Full title: Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)

Authors: Foggin, Sophie

Year: 2022

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/71220/1/Sophie_Foggin_Thesis_2022_Corrections.pdf

Thesis Does the activity of the proteasome decline during human ageing and in the brains of Parkinson’s disease patients?

Wayne, Declan · 2018 · University of Nottingham · DOI

Full title: Does the activity of the proteasome decline during human ageing and in the brains of Parkinson’s disease patients?

Authors: Wayne, Declan

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/55407/1/Thesis%20UPS%20in%20Parkinsons%20and%20Ageing%20Declan%20Wayne%20Finalised.pdf

Thesis Exploring Lysosomal pH as a Therapeutic Strategy for Neurodegeneration

Chin, Marcus Yu-Yeung · 2021 · University of California, San Francisco (UCSF) · DOI

Full title: Exploring Lysosomal pH as a Therapeutic Strategy for Neurodegeneration

Authors: Chin, Marcus Yu-Yeung

Year: 2021

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/3xs387n6

Thesis Synthesis of Alpha-Synuclein Proteolytic Targeting Chimeras and Selective Tau Tubulin Kinase I Inhibitors

Buczynski, Stanley · 2022 · University of California, San Diego (UCSD) · DOI

Full title: Synthesis of Alpha-Synuclein Proteolytic Targeting Chimeras and Selective Tau Tubulin Kinase I Inhibitors

Authors: Buczynski, Stanley

Year: 2022

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/8cg624p0

Thesis Regulation of mitochondrial autophagy by huntingtin

Margulis, Julia · 2016 · University of California, San Francisco (UCSF) · DOI

Full title: Regulation of mitochondrial autophagy by huntingtin

Authors: Margulis, Julia

Year: 2016

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/8kn713ss

Thesis Mitochondrial degradation and chronic hyperactivity in Parkinson’s disease

Doric, Zak · 2022 · University of California, San Francisco (UCSF) · DOI

Full title: Mitochondrial degradation and chronic hyperactivity in Parkinson’s disease

Authors: Doric, Zak

Year: 2022

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/5qj1z426

Thesis Targeting mitochondria as a potential therapeutic strategy in neurodegenerative disease

Hu, Di · 2019 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Targeting mitochondria as a potential therapeutic strategy in neurodegenerative disease

Authors: Hu, Di

Year: 2019

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1559999737544078

Thesis Investigations into the cellular function of C9orf72

Webster, Christopher · 2016 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Investigations into the cellular function of C9orf72

Authors: Webster, Christopher

Year: 2016

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/14385/1/160720_Thesis_Corrected.pdf

Thesis Exploration of the role of TBK1 in autophagy and Amyotrophic Lateral Sclerosis

Davies, Maria · 2019 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Exploration of the role of TBK1 in autophagy and Amyotrophic Lateral Sclerosis

Authors: Davies, Maria

Year: 2019

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/25167/1/Maria%20Davies%20Thesis%20October%202019.pdf

Thesis Mechanisms of motor and non-motor complications in experimental parkinsonism

Carina Plewnia (18648865) · 2023 · Karolinska Institutet · DOI

Full title: Mechanisms of motor and non-motor complications in experimental parkinsonism

Authors: Carina Plewnia (18648865)

Year: 2023

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26915920

Thesis Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease

Richeng Jiang (18661627) · 2022 · Karolinska Institutet · DOI

Full title: Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease

Authors: Richeng Jiang (18661627)

Year: 2022

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26925319

Thesis Drug discovery targeting non-amyloid pathways in Alzheimer’s disease

Märta Dahlström (18681613) · 2020 · Karolinska Institutet · DOI

Full title: Drug discovery targeting non-amyloid pathways in Alzheimer’s disease

Authors: Märta Dahlström (18681613)

Year: 2020

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26921716

Thesis REGULATION OF PROTEIN AGGREGATION BY ARFAPTIN2 IN AMYOTROPHIC LATERAL SCLEROSIS

Mohammedeid, Aida · 2015 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: REGULATION OF PROTEIN AGGREGATION BY ARFAPTIN2 IN AMYOTROPHIC LATERAL SCLEROSIS

Authors: Mohammedeid, Aida

Year: 2015

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/9377/1/Aida%20Mohammedeid%20final%20thesis.pdf

Thesis The role of autophagy in Aβ and tau metabolism in Alzheimer’s disease

Johanna Mayer (18664930) · 2024 · Karolinska Institutet · DOI

Full title: The role of autophagy in Aβ and tau metabolism in Alzheimer’s disease

Authors: Johanna Mayer (18664930)

Year: 2024

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26921809

Thesis Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Romani, Mario · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Authors: Romani, Mario

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/175117

Thesis Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

Mosser, Sébastien · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

Authors: Mosser, Sébastien

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/123330

Thesis Development of novel therapeutic approaches for treatment of Alzheimer's disease

Choo, Xin Yi · 2018 · University of Melbourne · DOI

Full title: Development of novel therapeutic approaches for treatment of Alzheimer's disease

Authors: Choo, Xin Yi

Year: 2018

Venue: University of Melbourne

DOI: http://hdl.handle.net/11343/216470

Thesis Molecular and cellular insights into mitochondrial contributions to neuronal autophagy: links to energetics and mitophagy

SHIN, YEA SEUL · 2016 · University of Melbourne · DOI

Full title: Molecular and cellular insights into mitochondrial contributions to neuronal autophagy: links to energetics and mitophagy

Authors: SHIN, YEA SEUL

Year: 2016

Venue: University of Melbourne

DOI: http://hdl.handle.net/11343/103644

Thesis Trehalose: a sweet solution for neurodegeneration?

Portbury, Stuart · 2017 · University of Melbourne · DOI

Full title: Trehalose: a sweet solution for neurodegeneration?

Authors: Portbury, Stuart

Year: 2017

Venue: University of Melbourne

DOI: http://hdl.handle.net/11343/194877

Thesis Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration?

Liddell, JR · 2018 · University of Melbourne · DOI

Full title: Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration?

Authors: Liddell, JR

Year: 2018

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/198168

Thesis Development and application of advanced bioimaging techniques to investigate stress pathways and drug action in neurodegeneration

James, Janine Louise · 2019 · University of Melbourne · DOI

Full title: Development and application of advanced bioimaging techniques to investigate stress pathways and drug action in neurodegeneration

Authors: James, Janine Louise

Year: 2019

Venue: University of Melbourne

DOI: http://hdl.handle.net/11343/228831

Thesis Could Alzheimer’s Disease Originate in the Periphery and If So How So?

Morris, G; Berk, M; Maes, M et al. · 2020 · University of Melbourne · DOI

Full title: Could Alzheimer’s Disease Originate in the Periphery and If So How So?

Authors: Morris, G; Berk, M; Maes, M; Puri, BK

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/254971

Thesis Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Tuo, QZ; Zhang, ST; Lei, P · 2022 · University of Melbourne · DOI

Full title: Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Authors: Tuo, QZ; Zhang, ST; Lei, P

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/298538

Thesis Autophagy-inducing peptides as a therapy for Amyotrophic lateral sclerosis

Amin, Azin · 2022 · University of Melbourne · DOI

Full title: Autophagy-inducing peptides as a therapy for Amyotrophic lateral sclerosis

Authors: Amin, Azin

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/311850

Thesis Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Jiang, Q; Liu, J; Huang, S et al. · 2025 · University of Melbourne · DOI

Full title: Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Authors: Jiang, Q; Liu, J; Huang, S; Wang, XY; Chen, X; Liu, GH; Ye, K; Song, W; Masters, CL; Wang, J; Wang, YJ

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360219

Thesis Using Caenorhabditis elegans to fight human neurodegenerative diseases

Chen, Xi; Kraemer, Brian; Barclay, Jeff et al. · 2013 · University of Liverpool · DOI

Full title: Using Caenorhabditis elegans to fight human neurodegenerative diseases

Authors: Chen, Xi; Kraemer, Brian; Barclay, Jeff; Burgoyne, Robert; Morgan, Alan

Year: 2013

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/2005121/5/ChenXi_Sep2014_2005121.pdf

Thesis Modeling and Mechanistic Investigation of α-synuclein aggregation

Svanbergsson, Alexander · 2021 · Lund University (LUP) · DOI

Full title: Modeling and Mechanistic Investigation of α-synuclein aggregation

Authors: Svanbergsson, Alexander

Year: 2021

Venue: Lund University (LUP)

DOI: https://lup.lub.lu.se/record/cfaf28f7-c763-4223-9483-75daaeec1ad9

Thesis Pharmacological and genetic manipulation of autophagy and its impact on diverse prion infection scenarios

Aguib, Yasmine · 2012 · Technical University of Munich · DOI

Full title: Pharmacological and genetic manipulation of autophagy and its impact on diverse prion infection scenarios

Authors: Aguib, Yasmine

Year: 2012

Venue: Technical University of Munich

DOI: https://mediatum.ub.tum.de/1108173

Thesis Role of Neuroinflammation in Parkinson's Disease and Related Disorders

Brandi, Edoardo · 2022 · Lund University (LUP) · DOI

Full title: Role of Neuroinflammation in Parkinson's Disease and Related Disorders

Authors: Brandi, Edoardo

Year: 2022

Venue: Lund University (LUP)

DOI: https://lup.lub.lu.se/record/bfd651d7-e127-4afc-86fe-bfc8c76baa72

Thesis Correlative cryo-electron tomography studies of artificial beta-protein aggregates in mammalian cells

Schäfer, Tillman · 2018 · Technical University of Munich (TUM) · DOI

Full title: Correlative cryo-electron tomography studies of artificial beta-protein aggregates in mammalian cells

Authors: Schäfer, Tillman

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1452151

Thesis Prions and autophagy: Effect of lithium on prion infection and role of basal autophagy in primary prion infection

Heiseke, Andreas · 2010 · Technical University of Munich · DOI

Full title: Prions and autophagy: Effect of lithium on prion infection and role of basal autophagy in primary prion infection

Authors: Heiseke, Andreas

Year: 2010

Venue: Technical University of Munich

DOI: https://mediatum.ub.tum.de/818228

Thesis Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor et al. · 2018 · Colorado State University · DOI

Full title: Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Authors: Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor; Tsunoda, Susan, committee member

Year: 2018

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/191325

Thesis Glial inflammation as a key regulator and therapeutic target for prion disease

Hay, Arielle, author; Zabel, Mark, advisor; Moreno, Julie, advisor et al. · 2023 · Colorado State University · DOI

Full title: Glial inflammation as a key regulator and therapeutic target for prion disease

Authors: Hay, Arielle, author; Zabel, Mark, advisor; Moreno, Julie, advisor; Tjalkens, Ronald, committee member; Chanda, Soham, committee member; Santangelo, Kelly, committee member

Year: 2023

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/236942

Thesis Defective Autophagy in Neurodegeneration: Novel Roles for Huntingtin and Optineurin in Regulating Autophagosome Dynamics

Wong, Chyi Haw Yvette · 2023 · University of Pennsylvania · DOI

Full title: Defective Autophagy in Neurodegeneration: Novel Roles for Huntingtin and Optineurin in Regulating Autophagosome Dynamics

Authors: Wong, Chyi Haw Yvette

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/27949

Thesis Structural Remodeling Of Alpha-Synuclein By Small Molecules: A Novel Path To Neuroprotective Therapeutics

Daniels, Malcolm James · 2023 · University of Pennsylvania · DOI

Full title: Structural Remodeling Of Alpha-Synuclein By Small Molecules: A Novel Path To Neuroprotective Therapeutics

Authors: Daniels, Malcolm James

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/29705

Thesis Engineering Protein Disaggregases To Counter Alpha-Synuclein And Amyloid-Beta Neurotoxicity

Mack, Korrie Lynne · 2023 · University of Pennsylvania · DOI

Full title: Engineering Protein Disaggregases To Counter Alpha-Synuclein And Amyloid-Beta Neurotoxicity

Authors: Mack, Korrie Lynne

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/30511

Thesis Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila

Saikumar, Janani · 2023 · University of Pennsylvania · DOI

Full title: Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila

Authors: Saikumar, Janani

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/31231

Thesis Structure And Function Of A Disease Associated Tau Disaggregase

Darwich, Nabil · 2023 · University of Pennsylvania · DOI

Full title: Structure And Function Of A Disease Associated Tau Disaggregase

Authors: Darwich, Nabil

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/30669

Thesis Increased Expression of Frontotemporal Dementia Risk Factor Tmem106b Alters Lysosomal and Autophagosomal Pathways

Busch, Johanna Irene · 2023 · University of Pennsylvania · DOI

Full title: Increased Expression of Frontotemporal Dementia Risk Factor Tmem106b Alters Lysosomal and Autophagosomal Pathways

Authors: Busch, Johanna Irene

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/28462

Thesis A Role for Lysosomal PH Dysfunction in Alzheimer’s Disease and Strategies for its Restoration

Coffey, Erin · 2023 · University of Pennsylvania · DOI

Full title: A Role for Lysosomal PH Dysfunction in Alzheimer’s Disease and Strategies for its Restoration

Authors: Coffey, Erin

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/28497

Thesis Proteostasis Responses to Endogenous Alpha-Synuclein Aggregation in the Brain

Ugras, Scott Edward · 2023 · University of Pennsylvania · DOI

Full title: Proteostasis Responses to Endogenous Alpha-Synuclein Aggregation in the Brain

Authors: Ugras, Scott Edward

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/28946

Thesis MITOPHAGY INITIATION IS IMPAIRED BY NEURODEGENERATIVE-LINKED MUTATIONS AND INDUCES NF-ĸB INFLAMMATION

Harding, Olivia · 2023 · University of Pennsylvania · DOI

Full title: MITOPHAGY INITIATION IS IMPAIRED BY NEURODEGENERATIVE-LINKED MUTATIONS AND INDUCES NF-ĸB INFLAMMATION

Authors: Harding, Olivia

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/58991

Thesis The Interplay Between Lewy Body-Like Alpha-Synuclein Aggregates nd Protein Degradation Pathways in Cell-Based Model of Parkinson's Disease

Tanik, Selcuk Aski · 2023 · University of Pennsylvania · DOI

Full title: The Interplay Between Lewy Body-Like Alpha-Synuclein Aggregates nd Protein Degradation Pathways in Cell-Based Model of Parkinson's Disease

Authors: Tanik, Selcuk Aski

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/32474

Thesis Compartment-Specific Regulation Of Autophagy In Neurons

Kulkarni, Vineet Vinay · 2023 · University of Pennsylvania · DOI

Full title: Compartment-Specific Regulation Of Autophagy In Neurons

Authors: Kulkarni, Vineet Vinay

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/31552

Thesis Regional Lysosomal Malfunction Underlies the Selectivity of α-Synuclein Neurodegeneration

Malkus, Kristen A · 2023 · University of Pennsylvania · DOI

Full title: Regional Lysosomal Malfunction Underlies the Selectivity of α-Synuclein Neurodegeneration

Authors: Malkus, Kristen A

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/32756

Thesis Mechanisms regulating the clearance of damaged lysosomes

Gallagher, Elizabeth, Raye · 2025 · University of Pennsylvania · DOI

Full title: Mechanisms regulating the clearance of damaged lysosomes

Authors: Gallagher, Elizabeth, Raye

Year: 2025

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/60816

Thesis Green Tea Catechins as a Prebiotic Intervention for Modulation of the Gut Microbiome, Metabolome, and Alpha-Synuclein in Parkinson’s Disease

Riegelman, Elizabeth C · 2025 · University of Georgia - UGA Open Scholar · DOI

Full title: Green Tea Catechins as a Prebiotic Intervention for Modulation of the Gut Microbiome, Metabolome, and Alpha-Synuclein in Parkinson’s Disease

Authors: Riegelman, Elizabeth C

Year: 2025

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/26630/files/ERiegelman_DissertationFINAL.pdf

Thesis EGCG directly targets intracellular amyloid-β(1-42) aggregates and promotes their lysosomal degradation

Secker, Christopher · 2019 · Freie Universität Berlin (Refubium) · DOI

Full title: EGCG directly targets intracellular amyloid-β(1-42) aggregates and promotes their lysosomal degradation

Authors: Secker, Christopher

Year: 2019

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/23977

Thesis The role of autophagy in Alzheimer disease

Jäger, Philipp · 2011 · Freie Universität Berlin (Refubium) · DOI

Full title: The role of autophagy in Alzheimer disease

Authors: Jäger, Philipp

Year: 2011

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/4120

Thesis Spermidine-induced autophagy and its effect on Alzheimer´s disease pathogenesis in mice

Freitag, Kiara · 2023 · Freie Universität Berlin (Refubium) · DOI

Full title: Spermidine-induced autophagy and its effect on Alzheimer´s disease pathogenesis in mice

Authors: Freitag, Kiara

Year: 2023

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/40859

Thesis Analysis of the interplay between protein quality control pathways in aging and neurodegenerative diseases

Rodrigues Feleciano, Diogo · 2019 · Freie Universität Berlin (Refubium) · DOI

Full title: Analysis of the interplay between protein quality control pathways in aging and neurodegenerative diseases

Authors: Rodrigues Feleciano, Diogo

Year: 2019

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/23722

Thesis Complementary methodologies and diverse model systems provide translational insight into the aggregation properties of neurodegenerative diseases

Pigazzini, Maria Lucia · 2022 · Freie Universität Berlin (Refubium) · DOI

Full title: Complementary methodologies and diverse model systems provide translational insight into the aggregation properties of neurodegenerative diseases

Authors: Pigazzini, Maria Lucia

Year: 2022

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/34073

Thesis Perturbations of proteostasis networks in Alzheimer´s disease: Focus on the ubiquitin proteasome system

Schormann, Eileen Josephine · 2019 · Freie Universität Berlin (Refubium) · DOI

Full title: Perturbations of proteostasis networks in Alzheimer´s disease: Focus on the ubiquitin proteasome system

Authors: Schormann, Eileen Josephine

Year: 2019

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/24086

Thesis Autophagy in Microglia and Alzheimer's disease

Houtman, Judith · 2019 · Freie Universität Berlin (Refubium) · DOI

Full title: Autophagy in Microglia and Alzheimer's disease

Authors: Houtman, Judith

Year: 2019

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/25471

Thesis Modifying prion disease development by ablation of galectin-3 and by simvastatin-treatment

Mok, Simon Wing-Fai · 2012 · Freie Universität Berlin (Refubium) · DOI

Full title: Modifying prion disease development by ablation of galectin-3 and by simvastatin-treatment

Authors: Mok, Simon Wing-Fai

Year: 2012

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/8203

Thesis Autophagy and its role in synapse function

Hoffmann, Sheila Sook-Hi · 2019 · Freie Universität Berlin (Refubium) · DOI

Full title: Autophagy and its role in synapse function

Authors: Hoffmann, Sheila Sook-Hi

Year: 2019

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/24487

Thesis Mechanistic target of rapamycin is required for sensory axon regeneration and functional recovery

Chen, Weitao · 2018 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Mechanistic target of rapamycin is required for sensory axon regeneration and functional recovery

Authors: Chen, Weitao

Year: 2018

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-114526

Thesis α-synuclein degradation dynamics and the evaluation of a new mouse model in Parkinson’s disease

Lam, Wai Yun · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: α-synuclein degradation dynamics and the evaluation of a new mouse model in Parkinson’s disease

Authors: Lam, Wai Yun

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-129891

Thesis Functional characterization of Cdk5-mediated phosphorylation of endophilin B1 in macroautophagy in models of parkinson's disease

Wong, Siu Lun · 2011 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Functional characterization of Cdk5-mediated phosphorylation of endophilin B1 in macroautophagy in models of parkinson's disease

Authors: Wong, Siu Lun

Year: 2011

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-7348

Thesis Improving Mitochondrial Function in the Aging and Diseased Brain

Ng, Jin · 2019 · University of Auckland · DOI

Full title: Improving Mitochondrial Function in the Aging and Diseased Brain

Authors: Ng, Jin

Year: 2019

Venue: University of Auckland

DOI: https://hdl.handle.net/2292/46858

Thesis Mitochondria: An Emerging Therapeutic Target for Neurodegeneration

Dhar, Krishayant Shiri · 2025 · University of Sydney · DOI

Full title: Mitochondria: An Emerging Therapeutic Target for Neurodegeneration

Authors: Dhar, Krishayant Shiri

Year: 2025

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/34175

Thesis Identification of Novel Modulators for Neurodegenerative Disease States

Garrett, Taylor Ray · 2025 · University of Sydney · DOI

Full title: Identification of Novel Modulators for Neurodegenerative Disease States

Authors: Garrett, Taylor Ray

Year: 2025

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/33832

Thesis The role of autophagy in TLR2-mediated alpha-synuclein accumulation in neurons.

Chedid, Jessica · 2023 · University of Sydney · DOI

Full title: The role of autophagy in TLR2-mediated alpha-synuclein accumulation in neurons.

Authors: Chedid, Jessica

Year: 2023

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/31817

Thesis Identification de molécules neuroprotectrices, facteurs de transcription et voies de signalisation en jeu pour la maladie de Machado-Joseph par un modèle transgénique C. elegans

Fard Ghassemi, Yasmin · 2022 · Université de Montréal (Papyrus) · DOI

Full title: Identification de molécules neuroprotectrices, facteurs de transcription et voies de signalisation en jeu pour la maladie de Machado-Joseph par un modèle transgénique C. elegans

Authors: Fard Ghassemi, Yasmin

Year: 2022

Venue: Université de Montréal (Papyrus)

DOI: http://hdl.handle.net/1866/26869

Thesis Autophagy-lysosomal pathway dysfunction in Parkinson’s disease

Murphy, Karen · 2013 · UNSW Sydney · DOI

Full title: Autophagy-lysosomal pathway dysfunction in Parkinson’s disease

Authors: Murphy, Karen

Year: 2013

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/53379

Thesis Investigating the potential role of the M1 muscarinic acetylcholine receptor in misfolded protein propagation

Alepuz Guillen, Jose Andres · 2024 · University of Glasgow · DOI

Full title: Investigating the potential role of the M1 muscarinic acetylcholine receptor in misfolded protein propagation

Authors: Alepuz Guillen, Jose Andres

Year: 2024

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/84698/1/2024AlepuzGuillenPhD.pdf

Thesis Dysregulated miRNA Expression in Parkinson’s Disease Results in Impaired Endocytosis, Mitochondrial Dysfunction and Lysosome Dyshomeostasis

Duly, Alastair · 2018 · UNSW Sydney · DOI

Full title: Dysregulated miRNA Expression in Parkinson’s Disease Results in Impaired Endocytosis, Mitochondrial Dysfunction and Lysosome Dyshomeostasis

Authors: Duly, Alastair

Year: 2018

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/61686

Thesis Clinical aspects and in vitro modelling of GBA1 variant-associated Parkinson's disease

Stoker, Thomas Benjamin · 2020 · University of Cambridge · DOI

Full title: Clinical aspects and in vitro modelling of GBA1 variant-associated Parkinson's disease

Authors: Stoker, Thomas Benjamin

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/301989

Thesis Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.

Kreiser, Ryan P; Wright, Aidan K; Block, Natalie R et al. · 2020 · University of Cambridge · DOI

Full title: Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.

Authors: Kreiser, Ryan P; Wright, Aidan K; Block, Natalie R; Hollows, Jared E; Nguyen, Lam T; LeForte, Kathleen; Mannini, Benedetta; Vendruscolo, Michele; Limbocker, Ryan

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/313119

Thesis Autophagy in major human diseases.

Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K et al. · 2021 · University of Cambridge · DOI

Full title: Autophagy in major human diseases.

Authors: Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine MK; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Gewirtz, David A; Green, Douglas R; Hansen, Malene; Jäättelä, Marja; Johansen, Terje; Juhász, Gábor; Karantza, Vassiliki; Kraft, Claudine; Kroemer, Guido; Ktistakis, Nicholas T; Kumar, Sharad; Lopez-Otin, Carlos; Macleod, Kay F; Madeo, Frank; Martinez, Jennifer; Meléndez, Alicia; Mizushima, Noboru; Münz, Christian; Penninger, Josef M; Perera, Rushika M; Piacentini, Mauro; Reggiori, Fulvio; Rubinsztein, David C; Ryan, Kevin M; Sadoshima, Junichi; Santambrogio, Laura; Scorrano, Luca; Simon, Hans-Uwe; Simon, Anna Katharina; Simonsen, Anne; Stolz, Alexandra; Tavernarakis, Nektarios; Tooze, Sharon A; Yoshimori, Tamotsu; Yuan, Junying; Yue, Zhenyu; Zhong, Qing; Galluzzi, Lorenzo; Pietrocola, Federico

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/325129

Thesis Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease

Barker, Roger · 2022 · University of Cambridge · DOI

Full title: Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease

Authors: Barker, Roger

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/332257

Thesis The different autophagy degradation pathways and neurodegeneration.

Fleming, Angeleen; Bourdenx, Mathieu; Fujimaki, Motoki et al. · 2022 · University of Cambridge · DOI

Full title: The different autophagy degradation pathways and neurodegeneration.

Authors: Fleming, Angeleen; Bourdenx, Mathieu; Fujimaki, Motoki; Karabiyik, Cansu; Krause, Gregory J; Lopez, Ana; Martín-Segura, Adrián; Puri, Claudia; Scrivo, Aurora; Skidmore, John; Son, Sung Min; Stamatakou, Eleanna; Wrobel, Lidia; Zhu, Ye; Cuervo, Ana Maria; Rubinsztein, David C

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/335336

Thesis Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Wrobel, Lidia; Hill, Sandra M; Djajadikerta, Alvin et al. · 2022 · University of Cambridge · DOI

Full title: Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Authors: Wrobel, Lidia; Hill, Sandra M; Djajadikerta, Alvin; Fernandez-Estevez, Marian; Karabiyik, Cansu; Ashkenazi, Avraham; Barratt, Victoria J; Stamatakou, Eleanna; Gunnarsson, Anders; Rasmusson, Timothy; Miele, Eric W; Beaton, Nigel; Bruderer, Roland; Feng, Yuehan; Reiter, Lukas; Castaldi, M Paola; Jarvis, Rebecca; Tan, Keith; Bürli, Roland W; Rubinsztein, David C

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/340198

Thesis Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.

Son, Sung Min; Siddiqi, Farah H; Lopez, Ana et al. · 2025 · University of Cambridge · DOI

Full title: Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.

Authors: Son, Sung Min; Siddiqi, Farah H; Lopez, Ana; Ansari, Rizwan; Tyrkalska, Sylwia D; Park, So Jung; Kunath, Tilo; Metzakopian, Emmanouil; Fleming, Angeleen; Rubinsztein, David C

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/381916

Thesis RNA binding proteins in neurotoxic protein clearance

Ryan, Laura · 2024 · University of Cambridge · DOI

Full title: RNA binding proteins in neurotoxic protein clearance

Authors: Ryan, Laura

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/370046

Thesis Human Embryonic stem cell-derived A9 dopaminergic neurons as a model and therapy for Parkinson's disease

Skidmore, Sophie · 2023 · University of Cambridge · DOI

Full title: Human Embryonic stem cell-derived A9 dopaminergic neurons as a model and therapy for Parkinson's disease

Authors: Skidmore, Sophie

Year: 2023

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/353732

Thesis Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion

Rubinsztein, David; Lopez, Ana; Siddiqi, Farah et al. · 2025 · University of Cambridge · DOI

Full title: Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion

Authors: Rubinsztein, David; Lopez, Ana; Siddiqi, Farah; Keeling, Sophie; McEwan, William; Fleming, Angeleen

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/374034

Thesis El papel del sistema autofágico lisosomal en las enfermedades con cuerpos de Lewy

Pérez Roca, Laia · 2021 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: El papel del sistema autofágico lisosomal en las enfermedades con cuerpos de Lewy

Authors: Pérez Roca, Laia

Year: 2021

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/672055

Thesis Investigation of the role and modulation of autophagy for neuroprotection and nerve regeneration using models of peripheral nerve injury

Leiva Rodríguez, Tatiana · 2019 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Investigation of the role and modulation of autophagy for neuroprotection and nerve regeneration using models of peripheral nerve injury

Authors: Leiva Rodríguez, Tatiana

Year: 2019

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/667461

Thesis Transcription factor EB-mediated neurotrophic and neuroprotective effects: relevance to Parkinson’s disease

Torra i Talavera, Albert · 2019 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Transcription factor EB-mediated neurotrophic and neuroprotective effects: relevance to Parkinson’s disease

Authors: Torra i Talavera, Albert

Year: 2019

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/667794

Thesis Therapeutic targeting of mitophagy in Parkinson's disease

Masaldan, S; Callegari, S; Dewson, G · 2022 · University of Melbourne · DOI

Full title: Therapeutic targeting of mitophagy in Parkinson's disease

Authors: Masaldan, S; Callegari, S; Dewson, G

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/308650

Thesis Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease

Portbury, SD; Hare, DJ; Sgambelloni, C et al. · 2020 · University of Melbourne · DOI

Full title: Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease

Authors: Portbury, SD; Hare, DJ; Sgambelloni, C; Perronnes, K; Portbury, AJ; Finkelstein, DI; Adlard, PA

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/256837

Thesis Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

Vessey, KA; Jobling, AI; Tran, MX et al. · 2022 · University of Melbourne · DOI

Full title: Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

Authors: Vessey, KA; Jobling, AI; Tran, MX; Wang, AY; Greferath, U; Fletcher, EL

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/302830

Thesis Amyotrophic lateral sclerosis and autophagy: Dysfunction and therapeutic targeting

Amin, A; Perera, ND; Beart, PM et al. · 2021 · University of Melbourne · DOI

Full title: Amyotrophic lateral sclerosis and autophagy: Dysfunction and therapeutic targeting

Authors: Amin, A; Perera, ND; Beart, PM; Turner, BJ; Shabanpoor, F

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/272091

Thesis The proteostasis network provides targets for neurodegeneration

Newton, TM; Duce, JA; Bayle, ED · 2021 · University of Melbourne · DOI

Full title: The proteostasis network provides targets for neurodegeneration

Authors: Newton, TM; Duce, JA; Bayle, ED

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/285815

Thesis Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

Wang, J; Bi, W; Zhao, W et al. · 2022 · University of Melbourne · DOI

Full title: Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

Authors: Wang, J; Bi, W; Zhao, W; Varghese, M; Koch, RJ; Walker, RH; Chandraratna, RA; Sanders, ME; Janesick, A; Blumberg, B; Ward, L; Ho, L; Pasinetti, GM

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316567

Thesis Therapeutics for dementia and Alzheimer's disease: New directions for precision medicine

Duce, JA; Zhu, X; Jacobson, LH et al. · 2021 · University of Melbourne · DOI

Full title: Therapeutics for dementia and Alzheimer's disease: New directions for precision medicine

Authors: Duce, JA; Zhu, X; Jacobson, LH; Beart, PM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/286279

Thesis Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson’s Disease Model

Azam, S; Haque, ME; Cho, DY et al. · 2022 · University of Melbourne · DOI

Full title: Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson’s Disease Model

Authors: Azam, S; Haque, ME; Cho, DY; Kim, JS; Jakaria, M; Kim, IS; Choi, DK

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/309009

Thesis Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Matysek, A; Kimmantudawage, SP; Feng, L et al. · 2022 · University of Melbourne · DOI

Full title: Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Authors: Matysek, A; Kimmantudawage, SP; Feng, L; Maier, AB

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/317284

Thesis Peroxisome proliferator activator receptor gamma coactivator-1α overexpression in amyotrophic lateral sclerosis: A tale of two transgenics

Varghese, M; Zhao, W; Trageser, KJ et al. · 2022 · University of Melbourne · DOI

Full title: Peroxisome proliferator activator receptor gamma coactivator-1α overexpression in amyotrophic lateral sclerosis: A tale of two transgenics

Authors: Varghese, M; Zhao, W; Trageser, KJ; Pasinetti, GM

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316565

Thesis Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

Choo, XY; McInnes, LE; Grubman, A et al. · 2022 · University of Melbourne · DOI

Full title: Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

Authors: Choo, XY; McInnes, LE; Grubman, A; Wasielewska, JM; Belaya, I; Burrows, E; Quek, H; Martín, JC; Loppi, S; Sorvari, A; Rait, D; Powell, A; Duncan, C; Liddell, JR; Tanila, H; Polo, JM; Malm, T; Kanninen, KM; Donnelly, PS; White, AR

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/322271

Thesis Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy

De Silva, S; Turner, BJ; Perera, ND · 2022 · University of Melbourne · DOI

Full title: Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy

Authors: De Silva, S; Turner, BJ; Perera, ND

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316752

Thesis Messenger RNA-encoded antibody approach for targeting extracellular and intracellular tau

Wongsodirdjo, P; Caruso, AC; Yong, AK et al. · 2024 · University of Melbourne · DOI

Full title: Messenger RNA-encoded antibody approach for targeting extracellular and intracellular tau

Authors: Wongsodirdjo, P; Caruso, AC; Yong, AK; Lester, MA; Vella, LJ; Hung, YH; Nisbet, RM

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/344638

Thesis Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans

Wu, Y; Chen, Y; Yu, X et al. · 2024 · University of Melbourne · DOI

Full title: Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans

Authors: Wu, Y; Chen, Y; Yu, X; Zhang, M; Li, Z

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/353037

Thesis In vivo Assessment of Lysosomal Stress in the Drosophila Brain Using Confocal Fluorescence Microscopy

Martelli, F · 2024 · University of Melbourne · DOI

Full title: In vivo Assessment of Lysosomal Stress in the Drosophila Brain Using Confocal Fluorescence Microscopy

Authors: Martelli, F

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/354186

Thesis Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

· 2025 · University of Melbourne · DOI

Full title: Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/362674

Thesis A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis

Lum, JS; Brown, ML; Farrawell, NE et al. · 2025 · University of Melbourne · DOI

Full title: A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis

Authors: Lum, JS; Brown, ML; Farrawell, NE; Bartlett, R; Chisholm, CG; Gorman, J; Dosseto, A; Dux, F; McInnes, LE; Ecroyd, H; McAlary, L; Crouch, PJ; Donnelly, PS; Yerbury, JJ

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360500

Thesis CLN5 deficiency results in alterations in the activation of autophagy

Budden, Theodore · 2015 · Kansas State University - K-REx · DOI

Full title: CLN5 deficiency results in alterations in the activation of autophagy

Authors: Budden, Theodore

Year: 2015

Venue: Kansas State University - K-REx

DOI: http://hdl.handle.net/2097/20473

Thesis Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

Sedlackova, Lucia; Otten, Elsje; Scialo, Filippo et al. · 2020 · University of Liverpool · DOI

Full title: Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

Authors: Sedlackova, Lucia; Otten, Elsje; Scialo, Filippo; Shapira, David; Kataura, Tetsushi; Carroll, Bernadette; Seranova, Elena; Rabanal-Ruiz, Yoana; Kelly, George; Stefanatos, Rhoda; Nelson, Glyn; Urselli, Francesca; Acharjee, Animesh; Kenneth, Niall; Trushin, Sergey; Zhang, Tong; Bascom, Charles; Tasseff, Ryan; Isfort, Robert; Oblong, John; Trushina, Eugenia; Imoto, Masaya; Saiki, Shinji; Lazarou, Michael; Papamichos Chronakis, Manolis; Maddocks, Oliver DK; Sarkar, Sovan; Sanz, Alberto; Korolchuk, Viktor

Year: 2020

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3139242

Thesis Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Chen, Xi; McCuef, Hannah V; Wong, Shi Quan et al. · 2015 · University of Liverpool · DOI

Full title: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Authors: Chen, Xi; McCuef, Hannah V; Wong, Shi Quan; Kashyap, Sudhanva S; Kraemer, Brian C; Barclay, Jeff W; Burgoyne, Robert D; Morgan, Alan

Year: 2015

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3000235/1/Ethosuximide%20ameliorates%20neurodegenerative%20disease%20phenotypes%20by%20modulating%20DAF-16/FOXO%20target%20gene%20expression.pdf

Thesis Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

Källstig, Emma · 2017 · Lund University Student Papers · DOI

Full title: Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

Authors: Källstig, Emma

Year: 2017

Venue: Lund University Student Papers

DOI: http://lup.lub.lu.se/student-papers/record/8925257

Thesis Extracellular Vesicles, Cell-Penetrating Peptides and miRNAs as Future Novel Therapeutic Interventions for Parkinson's and Alzheimer's Disease

Keighron, Cameron Noah; Avazzadeh, Sahar; Goljanek-Whysall, Katarzyna et al. · 2023 · University of Liverpool · DOI

Full title: Extracellular Vesicles, Cell-Penetrating Peptides and miRNAs as Future Novel Therapeutic Interventions for Parkinson's and Alzheimer's Disease

Authors: Keighron, Cameron Noah; Avazzadeh, Sahar; Goljanek-Whysall, Katarzyna; McDonagh, Brian; Howard, Linda; Ritter, Thomas; Quinlan, Leo RR

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3170448/1/Extracellular%20Vesicles%2C%20Cell-Penetrating%20Peptides%20and%20miRNAs%20as%20Future%20Novel%20Therapeutic%20Interventions%20for%20Parkinsons%20and%20Al.pdf

Thesis Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Hoffmann, Anna-Carin; Minakaki, Georgia; Menges, Stefanie et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Authors: Hoffmann, Anna-Carin;Minakaki, Georgia;Menges, Stefanie;Salvi, Rachele;Savitskiy, Sergey;Kazman, Aida;Vicente Miranda, Hugo;Mielenz, Dirk;Klucken, Jochen;Winkler, Jürgen;Xiang, Wei

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1544300

Thesis Using cannabidiol and trazodone to treat protein misfolding neurodegenerative disease in C. elegans

Gilberto, Vincenzo S., author; Moreno, Julie A., advisor; Legare, Marie, committee member et al. · 2022 · Colorado State University · DOI

Full title: Using cannabidiol and trazodone to treat protein misfolding neurodegenerative disease in C. elegans

Authors: Gilberto, Vincenzo S., author; Moreno, Julie A., advisor; Legare, Marie, committee member; McGrath, Stephanie, committee member; Popichak, Katriana, committee member; Dooley, Gregory, committee member

Year: 2022

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/235653

Thesis The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Campagno, Keith E.; Mitchell, Claire H. · 2023 · University of Pennsylvania · DOI

Full title: The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Authors: Campagno, Keith E.; Mitchell, Claire H.

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/58680

Thesis Autophagy in the Eye: Implications for Ocular Cell Health

Frost, Laura S.; Mitchell, Claire H.; Boesze-Battaglia, Kathleen · 2023 · University of Pennsylvania · DOI

Full title: Autophagy in the Eye: Implications for Ocular Cell Health

Authors: Frost, Laura S.; Mitchell, Claire H.; Boesze-Battaglia, Kathleen

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/8962

Thesis Neue Wirkstoffe für die Therapie von Morbus Alzheimer, Morbus Parkinson und Chorea Huntington

Strohmeier, Barbara · 2017 · University of Veterinary Medicine Hannover (TiHo) · DOI

Full title: Neue Wirkstoffe für die Therapie von Morbus Alzheimer, Morbus Parkinson und Chorea Huntington

Authors: Strohmeier, Barbara

Year: 2017

Venue: University of Veterinary Medicine Hannover (TiHo)

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-110222

Thesis The role of PARK9 in zinc homeostasis, alpha-synuclein toxicity and Parkinson’s disease

Chan, Brian · 2011 · UNSW Sydney · DOI

Full title: The role of PARK9 in zinc homeostasis, alpha-synuclein toxicity and Parkinson’s disease

Authors: Chan, Brian

Year: 2011

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/51536

Thesis Investigating the ATP13A2 (PARK9) and a- Synuclein inter-relationship in Parkinson’s Disease

Cottle, Louise Ellen · 2018 · UNSW Sydney · DOI

Full title: Investigating the ATP13A2 (PARK9) and a- Synuclein inter-relationship in Parkinson’s Disease

Authors: Cottle, Louise Ellen

Year: 2018

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/60575

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Metadata only

Paper Mitochondrial biogenesis: An update

Popov, Lucia‐Doina · 2020 · Journal of Cellular and Molecular Medicine · DOI

Full title: Mitochondrial biogenesis: An update

Authors: Popov, Lucia‐Doina

Year: 2020

Venue: Journal of Cellular and Molecular Medicine

DOI: https://doi.org/10.1111/jcmm.15194

Paper Liraglutide ameliorates non-alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3-FOXO3a pathway.

Tong, Wenxin; Ju, Liping; Qiu, Miaoyan et al. · 2016 · Hepatology research : the official journal of the Japan Society of Hepatology · DOI

Full title: Liraglutide ameliorates non-alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3-FOXO3a pathway.

Authors: Tong, Wenxin; Ju, Liping; Qiu, Miaoyan; Xie, Qihai; Chen, Ying; Shen, Weili; Sun, Weihong; Wang, Weiqing; Tian, Jingyan

Year: 2016

Venue: Hepatology research : the official journal of the Japan Society of Hepatology

DOI: https://doi.org/10.1111/hepr.12634

Paper Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Corti, Olga; Blomgren, Klas; Poletti, Angelo et al. · 2020 · Journal of Neurochemistry · DOI

Full title: Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Authors: Corti, Olga; Blomgren, Klas; Poletti, Angelo; Beart, Philip M.

Year: 2020

Venue: Journal of Neurochemistry

DOI: https://doi.org/10.1111/jnc.15002

Paper IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.

Cong, Lu-Hong; Li, Tao; Wang, Hui et al. · 2020 · Journal of cellular and molecular medicine · DOI

Full title: IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.

Authors: Cong, Lu-Hong; Li, Tao; Wang, Hui; Wu, Yi-Na; Wang, Shu-Peng; Zhao, Yu-Yue; Zhang, Guo-Qiang; Duan, Jun

Year: 2020

Venue: Journal of cellular and molecular medicine

DOI: https://doi.org/10.1111/jcmm.15475

Paper Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.

Nopparat, Chutikorn; Sinjanakhom, Puritat; Govitrapong, Piyarat · 2017 · Journal of pineal research · DOI

Full title: Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.

Authors: Nopparat, Chutikorn; Sinjanakhom, Puritat; Govitrapong, Piyarat

Year: 2017

Venue: Journal of pineal research

DOI: https://doi.org/10.1111/jpi.12407

Paper Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students

Łepeta, Katarzyna; Lourenco, Mychael V.; Schweitzer, Barbara et al. · 2016 · Journal of Neurochemistry · DOI

Full title: Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students

Authors: Łepeta, Katarzyna; Lourenco, Mychael V.; Schweitzer, Barbara; Adami, Pamela V. Martino; Banerjee, Priyanjalee; Catuara‐Solarz, Silvina; Revenga, Mario de la Fuente; Guillem, Alain M.; Haidar, Mouna; Ijomone, Omamuyovwi M.; Nadorp, Bettina; Qi, Lin; Perera, Nirma D.; Refsgaard, Louise K.; Reid, Kimberley M.; Sabbar, Mariam; Sahoo, Arghyadip; Schaefer, Natascha; Sheean, Rebecca K.; Suska, Anna; Verma, Rajkumar; Vicidomini, Cinzia; Wright, Dean; Zhang, Xing‐Ding; Seidenbecher, Constanze I.

Year: 2016

Venue: Journal of Neurochemistry

DOI: https://doi.org/10.1111/jnc.13713

Paper Ischaemia reperfusion injury in liver transplantation: Cellular and molecular mechanisms

Dar, Wasim; Sullivan, Elise; Bynon, John S. et al. · 2019 · Liver International · DOI

Full title: Ischaemia reperfusion injury in liver transplantation: Cellular and molecular mechanisms

Authors: Dar, Wasim; Sullivan, Elise; Bynon, John S.; Eltzschig, Holger K.; Ju, Cynthia

Year: 2019

Venue: Liver International

DOI: https://doi.org/10.1111/liv.14091

Paper Gradual downhill running improves age-related skeletal muscle and bone weakness: implication of autophagy and bone morphogenetic proteins.

Kim, Jeong-Seok; Lee, Young-Hee; Yi, Ho-Keun · 2016 · Experimental physiology · DOI

Full title: Gradual downhill running improves age-related skeletal muscle and bone weakness: implication of autophagy and bone morphogenetic proteins.

Authors: Kim, Jeong-Seok; Lee, Young-Hee; Yi, Ho-Keun

Year: 2016

Venue: Experimental physiology

DOI: https://doi.org/10.1113/EP085852

Paper Mitochondrial dysfunction in Parkinson's disease

Bose, Anindita; Beal, M. Flint · 2016 · Journal of Neurochemistry · DOI

Full title: Mitochondrial dysfunction in Parkinson's disease

Authors: Bose, Anindita; Beal, M. Flint

Year: 2016

Venue: Journal of Neurochemistry

DOI: https://doi.org/10.1111/jnc.13731

Paper A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autophagy in osteoclasts.

Wu, Xingwen; Sun, Yang; Cui, Renjie et al. · 2022 · Journal of periodontal research · DOI

Full title: A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autophagy in osteoclasts.

Authors: Wu, Xingwen; Sun, Yang; Cui, Renjie; Qiu, Wei; Zhang, Jin; Hu, Zhekai; Bi, Wei; Yang, Fei; Ma, Duan; Van Dyke, Thomas; Tu, Qisheng; Yu, Youcheng; Chen, Jake

Year: 2022

Venue: Journal of periodontal research

DOI: https://doi.org/10.1111/jre.12969

Paper The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Joseph disease.

Vasconcelos-Ferreira, Ana; Carmo-Silva, Sara; Codêsso, José Miguel et al. · 2022 · Neuropathology and applied neurobiology · DOI

Full title: The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Joseph disease.

Authors: Vasconcelos-Ferreira, Ana; Carmo-Silva, Sara; Codêsso, José Miguel; Silva, Patrick; Martinez, Alberto Rolim Muro; França, Marcondes Cavalcante; Nóbrega, Clévio; Pereira de Almeida, Luís

Year: 2022

Venue: Neuropathology and applied neurobiology

DOI: https://doi.org/10.1111/nan.12763

Paper Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.

Zhu, Zhao; Song, Jiaxin; Zhang, Chunmei et al. · 2024 · Oral diseases · DOI

Full title: Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.

Authors: Zhu, Zhao; Song, Jiaxin; Zhang, Chunmei; Zhang, Jing; Shan, Zhaochen

Year: 2024

Venue: Oral diseases

DOI: https://doi.org/10.1111/odi.14948

Paper The role of autophagy and lipid catabolism in enhancing cold stress resistance in zebrafish.

Trelford, Charles B; Wojtowicz, Stephanie; Banas, Caroline A · 2019 · The Journal of physiology · DOI

Full title: The role of autophagy and lipid catabolism in enhancing cold stress resistance in zebrafish.

Authors: Trelford, Charles B; Wojtowicz, Stephanie; Banas, Caroline A

Year: 2019

Venue: The Journal of physiology

DOI: https://doi.org/10.1113/JP277821

Paper Spermidine in health and disease

F. Madeo; T. Eisenberg; F. Pietrocola et al. · 2018 · Science · DOI

Full title: Spermidine in health and disease

Authors: F. Madeo; T. Eisenberg; F. Pietrocola; G. Kroemer

Year: 2018

Venue: Science

DOI: https://doi.org/10.1126/science.aan2788

Paper Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.

Zhou, Juan; Tan, Yingzheng; Hu, Lingli et al. · 2022 · Liver international : official journal of the International Association for the Study of the Liver · DOI

Full title: Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.

Authors: Zhou, Juan; Tan, Yingzheng; Hu, Lingli; Fu, Jingli; Li, Dan; Chen, Jun; Long, Yunzhu

Year: 2022

Venue: Liver international : official journal of the International Association for the Study of the Liver

DOI: https://doi.org/10.1111/liv.15459

Paper Translational evidence that impaired autophagy contributes to arterial ageing.

LaRocca, Thomas J; Henson, Grant D; Thorburn, Andrew et al. · 2012 · The Journal of physiology · DOI

Full title: Translational evidence that impaired autophagy contributes to arterial ageing.

Authors: LaRocca, Thomas J; Henson, Grant D; Thorburn, Andrew; Sindler, Amy L; Pierce, Gary L; Seals, Douglas R

Year: 2012

Venue: The Journal of physiology

DOI: https://doi.org/10.1113/jphysiol.2012.229690

Paper The role of lipids in exosome biology and intercellular communication: Function, analytics and applications

Donoso‐Quezada, Javier; Ayala‐Mar, Sergio; González‐Valdez, José · 2021 · Traffic · DOI

Full title: The role of lipids in exosome biology and intercellular communication: Function, analytics and applications

Authors: Donoso‐Quezada, Javier; Ayala‐Mar, Sergio; González‐Valdez, José

Year: 2021

Venue: Traffic

DOI: https://doi.org/10.1111/tra.12803

Paper An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

Hidvegi, Tunda; Ewing, Michael; Hale, Pamela et al. · 2010 · Science (New York, N.Y.) · DOI

Full title: An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

Authors: Hidvegi, Tunda; Ewing, Michael; Hale, Pamela; Dippold, Christine; Beckett, Caroline; Kemp, Carolyn; Maurice, Nicholas; Mukherjee, Amitava; Goldbach, Christina; Watkins, Simon; Michalopoulos, George; Perlmutter, David H

Year: 2010

Venue: Science (New York, N.Y.)

DOI: https://doi.org/10.1126/science.1190354

Paper Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein

Parr, Callum; Carzaniga, Raffaela; Gentleman, Steve et al. · 2012 · Molecular and Cellular Biology · DOI

Full title: Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein

Authors: Parr, Callum; Carzaniga, Raffaela; Gentleman, Steve; Leuven, Fred Van; Walter, Jochen; Sastre, Magdalena

Year: 2012

Venue: Molecular and Cellular Biology

DOI: https://doi.org/10.1128/mcb.00930-12

Paper Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy.

Ning, Yuping; Cai, Yi; Dai, Youchao et al. · 2021 · Infection and immunity · DOI

Full title: Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy.

Authors: Ning, Yuping; Cai, Yi; Dai, Youchao; Li, Fuxiang; Mo, Siwei; Werz, Oliver; Chen, Xinchun

Year: 2021

Venue: Infection and immunity

DOI: https://doi.org/10.1128/IAI.00306-21

Paper Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.

Xu, Lili; Shen, Jianjun; Dai, Shaobing et al. · 2020 · The American journal of Chinese medicine · DOI

Full title: Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.

Authors: Xu, Lili; Shen, Jianjun; Dai, Shaobing; Sun, Lihong; Chen, Xinzhong

Year: 2020

Venue: The American journal of Chinese medicine

DOI: https://doi.org/10.1142/S0192415X20500457

Paper Parkinson’s disease: etiopathogenesis and treatment

Jankovic, Joseph; Tan, Eng King · 2020 · Journal of Neurology Neurosurgery & Psychiatry · DOI

Full title: Parkinson’s disease: etiopathogenesis and treatment

Authors: Jankovic, Joseph; Tan, Eng King

Year: 2020

Venue: Journal of Neurology Neurosurgery & Psychiatry

DOI: https://doi.org/10.1136/jnnp-2019-322338

Paper Mycobacterium tuberculosis PPE51 Inhibits Autophagy by Suppressing Toll-Like Receptor 2-Dependent Signaling.

Strong, Emily J; Wang, Jia; Ng, Tony W et al. · 2022 · mBio · DOI

Full title: Mycobacterium tuberculosis PPE51 Inhibits Autophagy by Suppressing Toll-Like Receptor 2-Dependent Signaling.

Authors: Strong, Emily J; Wang, Jia; Ng, Tony W; Porcelli, Steven A; Lee, Sunhee

Year: 2022

Venue: mBio

DOI: https://doi.org/10.1128/mbio.02974-21

Paper Resveratrol attenuates hIAPP amyloid formation and restores the insulin secretion ability in hIAPP-INS1 cell line via enhancing autophagy.

Lv, Wu; Zhang, Jialin; Jiao, Ao et al. · 2019 · Canadian journal of physiology and pharmacology · DOI

Full title: Resveratrol attenuates hIAPP amyloid formation and restores the insulin secretion ability in hIAPP-INS1 cell line via enhancing autophagy.

Authors: Lv, Wu; Zhang, Jialin; Jiao, Ao; Wang, Bowen; Chen, Baomin; Lin, Jie

Year: 2019

Venue: Canadian journal of physiology and pharmacology

DOI: https://doi.org/10.1139/cjpp-2016-0686

Paper The Biology of Proteostasis in Aging and Disease

Labbadia, Johnathan; Morimoto, Richard I. · 2015 · Annual Review of Biochemistry · DOI

Full title: The Biology of Proteostasis in Aging and Disease

Authors: Labbadia, Johnathan; Morimoto, Richard I.

Year: 2015

Venue: Annual Review of Biochemistry

DOI: https://doi.org/10.1146/annurev-biochem-060614-033955

Paper Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in [Formula: see text] Mice.

Yang, Xiaodan; Shi, Jiaxi; He, Weifeng et al. · 2024 · The American journal of Chinese medicine · DOI

Full title: Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in [Formula: see text] Mice.

Authors: Yang, Xiaodan; Shi, Jiaxi; He, Weifeng; Li, Junlong; Li, Rui; Pi, Jianbin; Luo, Yuan; Gu, Mingyang; Wang, Xiaolong; Wu, Wei; Qing, Lijin

Year: 2024

Venue: The American journal of Chinese medicine

DOI: https://doi.org/10.1142/S0192415X24500940

Paper Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.

Hsu, Wei-Ti; Chen, Yi-Hung; Yang, Han-Bin et al. · 2020 · The American journal of Chinese medicine · DOI

Full title: Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain.

Authors: Hsu, Wei-Ti; Chen, Yi-Hung; Yang, Han-Bin; Lin, Jaung-Geng; Hung, Shih-Ya

Year: 2020

Venue: The American journal of Chinese medicine

DOI: https://doi.org/10.1142/S0192415X20500822

Paper Propagation of Protein Aggregation in Neurodegenerative Diseases

Vaquer‐Alicea, Jaime; Diamond, Marc I. · 2019 · Annual Review of Biochemistry · DOI

Full title: Propagation of Protein Aggregation in Neurodegenerative Diseases

Authors: Vaquer‐Alicea, Jaime; Diamond, Marc I.

Year: 2019

Venue: Annual Review of Biochemistry

DOI: https://doi.org/10.1146/annurev-biochem-061516-045049

Paper Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics

Frigerio, Carlo Sala; Strooper, Bart De · 2016 · Annual Review of Neuroscience · DOI

Full title: Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics

Authors: Frigerio, Carlo Sala; Strooper, Bart De

Year: 2016

Venue: Annual Review of Neuroscience

DOI: https://doi.org/10.1146/annurev-neuro-070815-014015

Paper Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease

Uhlig, Holm H.; Powrie, Fiona · 2018 · Annual Review of Immunology · DOI

Full title: Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease

Authors: Uhlig, Holm H.; Powrie, Fiona

Year: 2018

Venue: Annual Review of Immunology

DOI: https://doi.org/10.1146/annurev-immunol-042617-053055

Paper Brain Disorders Due to Lysosomal Dysfunction

Fraldi, Alessandro; Klein, Andrés D.; Medina, Diego L. et al. · 2016 · Annual Review of Neuroscience · DOI

Full title: Brain Disorders Due to Lysosomal Dysfunction

Authors: Fraldi, Alessandro; Klein, Andrés D.; Medina, Diego L.; Settembre, Carmine

Year: 2016

Venue: Annual Review of Neuroscience

DOI: https://doi.org/10.1146/annurev-neuro-070815-014031

Paper Autophagy: A Druggable Process

Morel, Étienne; Mehrpour, Maryam; Botti, Joëlle et al. · 2017 · The Annual Review of Pharmacology and Toxicology · DOI

Full title: Autophagy: A Druggable Process

Authors: Morel, Étienne; Mehrpour, Maryam; Botti, Joëlle; Dupont, Nicolas; Hamaï, Ahmed; Nascimbeni, Anna Chiara; Codogno, Patrice

Year: 2017

Venue: The Annual Review of Pharmacology and Toxicology

DOI: https://doi.org/10.1146/annurev-pharmtox-010716-104936

Paper β-Hydroxybutyrate: A Signaling Metabolite

Newman, John C.; Verdin, Eric · 2017 · Annual Review of Nutrition · DOI

Full title: β-Hydroxybutyrate: A Signaling Metabolite

Authors: Newman, John C.; Verdin, Eric

Year: 2017

Venue: Annual Review of Nutrition

DOI: https://doi.org/10.1146/annurev-nutr-071816-064916

Paper Genetics and Pathogenesis of Parkinson's Syndrome

Ye, Hui; Robak, Laurie; Yu, Meigen et al. · 2022 · Annual Review of Pathology Mechanisms of Disease · DOI

Full title: Genetics and Pathogenesis of Parkinson's Syndrome

Authors: Ye, Hui; Robak, Laurie; Yu, Meigen; Cykowski, Matthew D.; Shulman, Joshua

Year: 2022

Venue: Annual Review of Pathology Mechanisms of Disease

DOI: https://doi.org/10.1146/annurev-pathmechdis-031521-034145

Paper Apolipoprotein E in Alzheimer's Disease: An Update

Yu, Jin‐Tai; Tan, Lan; Hardy, John · 2014 · Annual Review of Neuroscience · DOI

Full title: Apolipoprotein E in Alzheimer's Disease: An Update

Authors: Yu, Jin‐Tai; Tan, Lan; Hardy, John

Year: 2014

Venue: Annual Review of Neuroscience

DOI: https://doi.org/10.1146/annurev-neuro-071013-014300

Paper The Microbiota-Gut-Brain Axis

Cryan, John F.; O’Riordan, Kenneth J.; Cowan, Caitlin S.M. et al. · 2019 · Physiological Reviews · DOI

Full title: The Microbiota-Gut-Brain Axis

Authors: Cryan, John F.; O’Riordan, Kenneth J.; Cowan, Caitlin S.M.; Sandhu, Kiran V.; Bastiaanssen, Thomaz F. S.; Boehme, Marcus; Codagnone, Martin G.; Cussotto, Sofia; Fülling, Christine; Golubeva, Anna V.; Guzzetta, Katherine E.; Jaggar, Minal; Long-Smith, Caitríona M.; Lyte, Joshua M.; Martin, Jason; Molinero-Perez, Alicia; Moloney, Gerard M.; Morelli, Emanuela; Morillas, Enrique; O’Connor, Rory; Cruz-Pereira, Joana S.; Peterson, Veronica L.; Rea, Kieran; Ritz, Nathaniel L.; Sherwin, Eoin; Spichak, Simon; Teichman, Emily M.; Wouw, Marcel van de; Ventura‐Silva, Ana Paula; Wallace-Fitzsimons, Shauna E.; Hyland, Niall P.; Clarke, Gerard; Dinan, Timothy G.

Year: 2019

Venue: Physiological Reviews

DOI: https://doi.org/10.1152/physrev.00018.2018

Paper TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.

Lin, Yijia; Cheng, Lizhen; Chen, Yixin et al. · 2024 · American journal of physiology. Cell physiology · DOI

Full title: TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.

Authors: Lin, Yijia; Cheng, Lizhen; Chen, Yixin; Li, Wei; Guo, Qihao; Miao, Ya

Year: 2024

Venue: American journal of physiology. Cell physiology

DOI: https://doi.org/10.1152/ajpcell.00322.2024

Paper Blood-Brain Barrier: From Physiology to Disease and Back

Sweeney, Melanie D.; Zhao, Zhen; Montagne, Axel et al. · 2018 · Physiological Reviews · DOI

Full title: Blood-Brain Barrier: From Physiology to Disease and Back

Authors: Sweeney, Melanie D.; Zhao, Zhen; Montagne, Axel; Nelson, Amy R.; Zloković, Berislav V.

Year: 2018

Venue: Physiological Reviews

DOI: https://doi.org/10.1152/physrev.00050.2017

Paper Parathyroid hormone-(1-34) ameliorated knee osteoarthritis in rats via autophagy.

Chen, Chung-Hwan; Ho, Mei-Ling; Chang, Ling-Hua et al. · 2018 · Journal of applied physiology (Bethesda, Md. : 1985) · DOI

Full title: Parathyroid hormone-(1-34) ameliorated knee osteoarthritis in rats via autophagy.

Authors: Chen, Chung-Hwan; Ho, Mei-Ling; Chang, Ling-Hua; Kang, Lin; Lin, Yi-Shan; Lin, Sung-Yen; Wu, Shun-Cheng; Chang, Je-Ken

Year: 2018

Venue: Journal of applied physiology (Bethesda, Md. : 1985)

DOI: https://doi.org/10.1152/japplphysiol.00871.2017

Paper Cellular Stress Responses: Cell Survival and Cell Death

Fulda, Simone; Gorman, Adrienne M.; Hori, Osamu et al. · 2010 · International Journal of Cell Biology · DOI

Full title: Cellular Stress Responses: Cell Survival and Cell Death

Authors: Fulda, Simone; Gorman, Adrienne M.; Hori, Osamu; Samali, Afshin

Year: 2010

Venue: International Journal of Cell Biology

DOI: https://doi.org/10.1155/2010/214074

Paper Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhancing autophagy.

Wang, Jinxu; Xin, Yueyang; Chu, Tiantian et al. · 2023 · Journal of neurophysiology · DOI

Full title: Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhancing autophagy.

Authors: Wang, Jinxu; Xin, Yueyang; Chu, Tiantian; Zhou, Yaqun; Liu, Cheng; Xu, Aijun

Year: 2023

Venue: Journal of neurophysiology

DOI: https://doi.org/10.1152/jn.00019.2023

Paper Mechanism of Oxidative Stress in Neurodegeneration

Gandhi, Sonia; Abramov, Andrey Y. · 2012 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Mechanism of Oxidative Stress in Neurodegeneration

Authors: Gandhi, Sonia; Abramov, Andrey Y.

Year: 2012

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2012/428010

Paper A Review of Pterostilbene Antioxidant Activity and Disease Modification

McCormack, Denise; McFadden, David W. · 2013 · Oxidative Medicine and Cellular Longevity · DOI

Full title: A Review of Pterostilbene Antioxidant Activity and Disease Modification

Authors: McCormack, Denise; McFadden, David W.

Year: 2013

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2013/575482

Paper Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

Bhullar, Khushwant S.; Rupasinghe, H.P. Vasantha · 2013 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

Authors: Bhullar, Khushwant S.; Rupasinghe, H.P. Vasantha

Year: 2013

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2013/891748

Paper Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

Tarozzi, Andrea; Angeloni, Cristina; Malaguti, Marco et al. · 2013 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

Authors: Tarozzi, Andrea; Angeloni, Cristina; Malaguti, Marco; Morroni, Fabiana; Hrelia, Silvana; Hrelia, Patrizia

Year: 2013

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2013/415078

Paper Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease

Verdile, Giuseppe; Keane, Kevin N.; Cruzat, Vínicius Fernandes et al. · 2015 · Mediators of Inflammation · DOI

Full title: Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease

Authors: Verdile, Giuseppe; Keane, Kevin N.; Cruzat, Vínicius Fernandes; Medic, Sandra; Sabale, Miheer; Rowles, Joanne; Wijesekara, Nadeeja; Martins, Ralph N.; Fraser, Paul E.; Newsholme, Philip

Year: 2015

Venue: Mediators of Inflammation

DOI: https://doi.org/10.1155/2015/105828

Paper Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Chistiakov, Dimitry A.; Sobenin, Igor A.; Ревин, В. В. et al. · 2014 · BioMed Research International · DOI

Full title: Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Authors: Chistiakov, Dimitry A.; Sobenin, Igor A.; Ревин, В. В.; Orekhov, Alexander N.; Bobryshev, Yuri V.

Year: 2014

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2014/238463

Paper Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin

Maiti, Panchanan; Manna, Jayeeta; Veleri, Shobi et al. · 2014 · BioMed Research International · DOI

Full title: Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin

Authors: Maiti, Panchanan; Manna, Jayeeta; Veleri, Shobi; Frautschy, Sally A.

Year: 2014

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2014/495091

Paper Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

Costa, Lucio G.; Garrick, Jacqueline M.; Roqué, Pamela J. et al. · 2016 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

Authors: Costa, Lucio G.; Garrick, Jacqueline M.; Roqué, Pamela J.; Pellacani, Claudia

Year: 2016

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2016/2986796

Paper Diabetes and the Brain: Oxidative Stress, Inflammation, and Autophagy

Muriach, María; Flores‐Bellver, Miguel; Romero, Francisco J. et al. · 2014 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Diabetes and the Brain: Oxidative Stress, Inflammation, and Autophagy

Authors: Muriach, María; Flores‐Bellver, Miguel; Romero, Francisco J.; Barcia, Jorge M.

Year: 2014

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2014/102158

Paper ROS and Brain Diseases: The Good, the Bad, and the Ugly

Popa‐Wagner, Aurel; Mitran, Smaranda Ioana; Sivanesan, Senthilkumar et al. · 2013 · Oxidative Medicine and Cellular Longevity · DOI

Full title: ROS and Brain Diseases: The Good, the Bad, and the Ugly

Authors: Popa‐Wagner, Aurel; Mitran, Smaranda Ioana; Sivanesan, Senthilkumar; Chang, Edwin; Buga, Ana-Maria

Year: 2013

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2013/963520

Paper Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy.

Xiao, Jia; Guo, Rui; Fung, Man-Lung et al. · 2013 · Evidence-based complementary and alternative medicine : eCAM · DOI

Full title: Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy.

Authors: Xiao, Jia; Guo, Rui; Fung, Man-Lung; Liong, Emily C; Chang, Raymond Chuen Chung; Ching, Yick-Pang; Tipoe, George L

Year: 2013

Venue: Evidence-based complementary and alternative medicine : eCAM

DOI: https://doi.org/10.1155/2013/642920

Paper Vitamin D3 improved erectile function recovery by regulating autophagy and apoptosis in a rat model of cavernous nerve injury.

Zhu, Shiyu; Xiong, Yang; Yu, Botao et al. · 2024 · International journal of impotence research · DOI

Full title: Vitamin D3 improved erectile function recovery by regulating autophagy and apoptosis in a rat model of cavernous nerve injury.

Authors: Zhu, Shiyu; Xiong, Yang; Yu, Botao; Wang, Hao; Zhang, Fuxun; Wu, Changjing; Qin, Feng; Yuan, Jiuhong

Year: 2024

Venue: International journal of impotence research

DOI: https://doi.org/10.1038/s41443-023-00679-4

Paper Lysosomes as a therapeutic target

Bonam, Srinivasa Reddy; Wang, Fengjuan; Muller, Sylviane · 2019 · Nature Reviews Drug Discovery · DOI

Full title: Lysosomes as a therapeutic target

Authors: Bonam, Srinivasa Reddy; Wang, Fengjuan; Muller, Sylviane

Year: 2019

Venue: Nature Reviews Drug Discovery

DOI: https://doi.org/10.1038/s41573-019-0036-1

Paper AMP-activated protein kinase: the current landscape for drug development

Steinberg, Gregory R.; Carling, David · 2019 · Nature Reviews Drug Discovery · DOI

Full title: AMP-activated protein kinase: the current landscape for drug development

Authors: Steinberg, Gregory R.; Carling, David

Year: 2019

Venue: Nature Reviews Drug Discovery

DOI: https://doi.org/10.1038/s41573-019-0019-2

Paper Context-specific regulation and function of mRNA alternative polyadenylation

Mitschka, Sibylle; Mayr, Christine · 2022 · Nature Reviews Molecular Cell Biology · DOI

Full title: Context-specific regulation and function of mRNA alternative polyadenylation

Authors: Mitschka, Sibylle; Mayr, Christine

Year: 2022

Venue: Nature Reviews Molecular Cell Biology

DOI: https://doi.org/10.1038/s41580-022-00507-5

Paper Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation

Mead, Richard J.; Shan, Ning; Reiser, H. Joseph et al. · 2022 · Nature Reviews Drug Discovery · DOI

Full title: Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation

Authors: Mead, Richard J.; Shan, Ning; Reiser, H. Joseph; Marshall, Fiona H.; Shaw, Pamela J.

Year: 2022

Venue: Nature Reviews Drug Discovery

DOI: https://doi.org/10.1038/s41573-022-00612-2

Paper The mechanisms and roles of selective autophagy in mammals.

Vargas, Jose Norberto S; Hamasaki, Maho; Kawabata, Tsuyoshi et al. · 2023 · Nature reviews. Molecular cell biology · DOI

Full title: The mechanisms and roles of selective autophagy in mammals.

Authors: Vargas, Jose Norberto S; Hamasaki, Maho; Kawabata, Tsuyoshi; Youle, Richard J; Yoshimori, Tamotsu

Year: 2023

Venue: Nature reviews. Molecular cell biology

DOI: https://doi.org/10.1038/s41580-022-00542-2

Paper Targeting the biology of aging with mTOR inhibitors

Mannick, Joan B.; Lamming, Dudley W. · 2023 · Nature Aging · DOI

Full title: Targeting the biology of aging with mTOR inhibitors

Authors: Mannick, Joan B.; Lamming, Dudley W.

Year: 2023

Venue: Nature Aging

DOI: https://doi.org/10.1038/s43587-023-00416-y

Paper Small molecule enhancers of autophagy for neurodegenerative diseases.

Sarkar, Sovan; Rubinsztein, David C · 2008 · Molecular bioSystems · DOI

Full title: Small molecule enhancers of autophagy for neurodegenerative diseases.

Authors: Sarkar, Sovan; Rubinsztein, David C

Year: 2008

Venue: Molecular bioSystems

DOI: https://doi.org/10.1039/b804606a

Paper Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.

Jin, Peipei; Wei, Pengfei; Zhang, Yunjiao et al. · 2016 · Nanoscale · DOI

Full title: Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.

Authors: Jin, Peipei; Wei, Pengfei; Zhang, Yunjiao; Lin, Jun; Sha, Rui; Hu, Yi; Zhang, Jiqian; Zhou, Wei; Yao, Han; Ren, Li; Yang, James Y; Liu, Yanchun; Wen, Longping

Year: 2016

Venue: Nanoscale

DOI: https://doi.org/10.1039/c6nr07255k

Paper MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.

Cerqueira, Fernanda M; Kozer, Noga; Petcherski, Anton et al. · 2020 · The Biochemical journal · DOI

Full title: MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.

Authors: Cerqueira, Fernanda M; Kozer, Noga; Petcherski, Anton; Baranovski, Boris M; Wolf, Dane; Assali, Essam A; Roth, Yaelle; Gazit, Roi; Barr, Haim; Lewis, Eli C; Las, Guy; Shirihai, Orian S

Year: 2020

Venue: The Biochemical journal

DOI: https://doi.org/10.1042/BCJ20190616

Paper Omega-3 PUFAs improve cognitive function in heat-stressed mice by enhancing autophagy via inhibition of the phosphorylation of the PI3K-Akt-mTOR pathway.

Ren, Zifu; Cai, Mengyu; Liu, Xinyao et al. · 2025 · Food & function · DOI

Full title: Omega-3 PUFAs improve cognitive function in heat-stressed mice by enhancing autophagy via inhibition of the phosphorylation of the PI3K-Akt-mTOR pathway.

Authors: Ren, Zifu; Cai, Mengyu; Liu, Xinyao; Li, Xin; Shi, Wenjing; Lu, Hongtao; Shen, Hui; Miao, Gen; Zhou, Qicheng; Li, Hongxia

Year: 2025

Venue: Food & function

DOI: https://doi.org/10.1039/d4fo04107k

Paper The protection of luteolin against diabetic cardiomyopathy in rats is related to reversing JNK-suppressed autophagy.

Xiao, Chi; Chen, Meng-Yuan; Han, Yu-Peng et al. · 2023 · Food & function · DOI

Full title: The protection of luteolin against diabetic cardiomyopathy in rats is related to reversing JNK-suppressed autophagy.

Authors: Xiao, Chi; Chen, Meng-Yuan; Han, Yu-Peng; Liu, Li-Juan; Yan, Jia-Lin; Qian, Ling-Bo

Year: 2023

Venue: Food & function

DOI: https://doi.org/10.1039/d2fo03871d

Paper Enhancing cognitive memory function using Phyllanthus emblica polysaccharides via modulating autophagy and reshaping the gut microbiota.

Chen, Jia-De; Chen, Sheng-Yi; Liao, Chia-Chien et al. · 2025 · Food & function · DOI

Full title: Enhancing cognitive memory function using Phyllanthus emblica polysaccharides via modulating autophagy and reshaping the gut microbiota.

Authors: Chen, Jia-De; Chen, Sheng-Yi; Liao, Chia-Chien; Fang, Cheng-Yu; Yen, Gow-Chin

Year: 2025

Venue: Food & function

DOI: https://doi.org/10.1039/d5fo03048j

Paper Citrus peel flavonoid nobiletin alleviates lipopolysaccharide-induced inflammation by activating IL-6/STAT3/FOXO3a-mediated autophagy.

Rong, Xue; Xu, Jie; Jiang, Yang et al. · 2021 · Food & function · DOI

Full title: Citrus peel flavonoid nobiletin alleviates lipopolysaccharide-induced inflammation by activating IL-6/STAT3/FOXO3a-mediated autophagy.

Authors: Rong, Xue; Xu, Jie; Jiang, Yang; Li, Feng; Chen, Yilun; Dou, Q Ping; Li, Dapeng

Year: 2021

Venue: Food & function

DOI: https://doi.org/10.1039/d0fo02141e

Paper HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.

Li, Jing; Zeng, Chuxiong; Zheng, Beishi et al. · 2018 · Clinical science (London, England : 1979) · DOI

Full title: HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.

Authors: Li, Jing; Zeng, Chuxiong; Zheng, Beishi; Liu, Chun; Tang, Min; Jiang, Yan; Chang, Yizhong; Song, Weiping; Wang, Yingxin; Yang, Changqing

Year: 2018

Venue: Clinical science (London, England : 1979)

DOI: https://doi.org/10.1042/CS20180177

Paper Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, Joseph; Lukácsovich, Tamás; Csikós, George et al. · 2014 · Proceedings of the National Academy of Sciences · DOI

Full title: Potential function for the Huntingtin protein as a scaffold for selective autophagy

Authors: Ochaba, Joseph; Lukácsovich, Tamás; Csikós, George; Zheng, Shuqiu; Margulis, Julia; Salazar, Lisa; Mao, Kai; Lau, Alice; Yeung, Sylvia Y.; Humbert, Sandrine; Saudou, Frédéric; Klionsky, Daniel J.; Finkbeiner, Steven; Zeitlin, Scott; Marsh, Joan; Housman, David E.; Thompson, Leslie M.; Steffan, Joan S.

Year: 2014

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1420103111

Paper Identification of small molecules enhancing autophagic function from drug network analysis.

Iorio, Francesco; Isacchi, Antonella; di Bernardo, Diego et al. · 2010 · Autophagy · DOI

Full title: Identification of small molecules enhancing autophagic function from drug network analysis.

Authors: Iorio, Francesco; Isacchi, Antonella; di Bernardo, Diego; Brunetti-Pierri, Nicola

Year: 2010

Venue: Autophagy

DOI: https://doi.org/10.1073/pnas.1000138107

Paper Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity.

Ma, Shuaiya; Wu, Qi; Wu, Wenxian et al. · 2024 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity.

Authors: Ma, Shuaiya; Wu, Qi; Wu, Wenxian; Tian, Ye; Zhang, Jie; Chen, Chaojia; Sheng, Xue; Zhao, Fangcheng; Ding, Lu; Wang, Taixia; Zhao, Laixi; Xie, Yuying; Wang, Yongxiang; Yue, Xuetian; Wu, Zhuanchang; Wei, Jian; Zhang, Kun; Liang, Xiaohong; Gao, Lifen; Wang, Hongyan; Wang, Guihua; Li, Chunyang; Ma, Chunhong

Year: 2024

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202310065

Paper Overexpression of lncRNA TCTN2 protects neurons from apoptosis by enhancing cell autophagy in spinal cord injury.

Ren, Xiao-Dong; Wan, Chun-Xiao; Niu, Ya-Li · 2019 · FEBS open bio · DOI

Full title: Overexpression of lncRNA TCTN2 protects neurons from apoptosis by enhancing cell autophagy in spinal cord injury.

Authors: Ren, Xiao-Dong; Wan, Chun-Xiao; Niu, Ya-Li

Year: 2019

Venue: FEBS open bio

DOI: https://doi.org/10.1002/2211-5463.12651

Paper Most autophagic cell death studies lack evidence of causality.

Özkaya, Ali Burak; Ghaseminejad, Yasmin · 2025 · FEBS open bio · DOI

Full title: Most autophagic cell death studies lack evidence of causality.

Authors: Özkaya, Ali Burak; Ghaseminejad, Yasmin

Year: 2025

Venue: FEBS open bio

DOI: https://doi.org/10.1002/2211-5463.70101

Paper Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha-Synuclein and Enhance Therapy of Parkinson's Disease.

Yuan, Jiaxin; Liu, Hanghang; Zhang, Hao et al. · 2022 · Advanced materials (Deerfield Beach, Fla.) · DOI

Full title: Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha-Synuclein and Enhance Therapy of Parkinson's Disease.

Authors: Yuan, Jiaxin; Liu, Hanghang; Zhang, Hao; Wang, Tingting; Zheng, Qing; Li, Zhen

Year: 2022

Venue: Advanced materials (Deerfield Beach, Fla.)

DOI: https://doi.org/10.1002/adma.202108435

Paper Tomatidine provides mitophagy-independent neuroprotection after ischemic injury.

Wang, Yu-Ting; Zhang, Li-Na; Lyu, Xiao-Cui et al. · 2021 · FEBS open bio · DOI

Full title: Tomatidine provides mitophagy-independent neuroprotection after ischemic injury.

Authors: Wang, Yu-Ting; Zhang, Li-Na; Lyu, Xiao-Cui; Li, Yue; Ahsan, Anil; Feng, Zikai; Zhang, Xiangnan

Year: 2021

Venue: FEBS open bio

DOI: https://doi.org/10.1002/2211-5463.13265

Paper Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine.

Baek, Eric; Lee, Jae Seong; Lee, Gyun Min · 2018 · Biotechnology and bioengineering · DOI

Full title: Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine.

Authors: Baek, Eric; Lee, Jae Seong; Lee, Gyun Min

Year: 2018

Venue: Biotechnology and bioengineering

DOI: https://doi.org/10.1002/bit.26777

Paper Iron and oxidizing species in oxidative stress and Alzheimer's disease

Zhao, Zhongwei · 2019 · Aging Medicine · DOI

Full title: Iron and oxidizing species in oxidative stress and Alzheimer's disease

Authors: Zhao, Zhongwei

Year: 2019

Venue: Aging Medicine

DOI: https://doi.org/10.1002/agm2.12074

Paper Daphnetin alleviates inflammation and promotes autophagy via the AMPK/mTOR pathway in gouty arthritis.

Liu, Zhiyong; Chu, Aichun; Bai, Zhiqian et al. · 2025 · Journal of cell communication and signaling · DOI

Full title: Daphnetin alleviates inflammation and promotes autophagy via the AMPK/mTOR pathway in gouty arthritis.

Authors: Liu, Zhiyong; Chu, Aichun; Bai, Zhiqian; Yang, Chao

Year: 2025

Venue: Journal of cell communication and signaling

DOI: https://doi.org/10.1002/ccs3.70011

Paper Autophagy drives plasticity and functional polarization of tumor‐associated macrophages

Kuo, Wan‐Ting; Chang, Jia‐Ming; Chen, Chien‐Chin et al. · 2021 · IUBMB Life · DOI

Full title: Autophagy drives plasticity and functional polarization of tumor‐associated macrophages

Authors: Kuo, Wan‐Ting; Chang, Jia‐Ming; Chen, Chien‐Chin; Tsao, Nina; Chang, Chih‐Peng

Year: 2021

Venue: IUBMB Life

DOI: https://doi.org/10.1002/iub.2543

Paper Autophagy-mediated chemosensitization by cysteamine in cancer cells.

Wan, Xiao-Mei; Zheng, Fang; Zhang, Li et al. · 2011 · International journal of cancer · DOI

Full title: Autophagy-mediated chemosensitization by cysteamine in cancer cells.

Authors: Wan, Xiao-Mei; Zheng, Fang; Zhang, Li; Miao, Yan-Yan; Man, Na; Wen, Long-Ping

Year: 2011

Venue: International journal of cancer

DOI: https://doi.org/10.1002/ijc.25771

Paper Reactive oxygen species in biological systems: Pathways, associated diseases, and potential inhibitors—A review

Rauf, Abdur; Khalil, Anees Ahmed; Awadallah, Samir et al. · 2023 · Food Science & Nutrition · DOI

Full title: Reactive oxygen species in biological systems: Pathways, associated diseases, and potential inhibitors—A review

Authors: Rauf, Abdur; Khalil, Anees Ahmed; Awadallah, Samir; Khan, Shahid Ali; Abu‐Izneid, Tareq; Kamran, Muhammad; Hemeg, Hassan A.; Mubarak, Mohammad S.; Khalid, Ahood; Wilairatana, Polrat

Year: 2023

Venue: Food Science & Nutrition

DOI: https://doi.org/10.1002/fsn3.3784

Paper Cannabidiol stimulates A ml‐1a‐dependent glial differentiation and inhibits glioma stem‐like cells proliferation by inducing autophagy in a TRPV 2‐dependent manner

Nabissi, Massimo; Morelli, Maria Beatrice; Amantini, Consuelo et al. · 2015 · International Journal of Cancer · DOI

Full title: Cannabidiol stimulates A ml‐1a‐dependent glial differentiation and inhibits glioma stem‐like cells proliferation by inducing autophagy in a TRPV 2‐dependent manner

Authors: Nabissi, Massimo; Morelli, Maria Beatrice; Amantini, Consuelo; Liberati, Sonia; Santoni, Matteo; Ricci‐Vitiani, Lucia; Pallini, Roberto; Santoni, Giorgio

Year: 2015

Venue: International Journal of Cancer

DOI: https://doi.org/10.1002/ijc.29573

Paper Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against Palmitate Lipotoxicity.

Mwangi, Simon Musyoka; Li, Ge; Ye, Lan et al. · 2019 · Hepatology (Baltimore, Md.) · DOI

Full title: Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against Palmitate Lipotoxicity.

Authors: Mwangi, Simon Musyoka; Li, Ge; Ye, Lan; Liu, Yunshan; Reichardt, Francois; Yeligar, Samantha M; Hart, C Michael; Czaja, Mark J; Srinivasan, Shanthi

Year: 2019

Venue: Hepatology (Baltimore, Md.)

DOI: https://doi.org/10.1002/hep.30541

Paper Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition.

Yamamura, Takeshi; Ohsaki, Yuki; Suzuki, Michitaka et al. · 2014 · Hepatology (Baltimore, Md.) · DOI

Full title: Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition.

Authors: Yamamura, Takeshi; Ohsaki, Yuki; Suzuki, Michitaka; Shinohara, Yuki; Tatematsu, Tsuyako; Cheng, Jinglei; Okada, Masato; Ohmiya, Naoki; Hirooka, Yoshiki; Goto, Hidemi; Fujimoto, Toyoshi

Year: 2014

Venue: Hepatology (Baltimore, Md.)

DOI: https://doi.org/10.1002/hep.26930

Paper Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.

Palumbo, Silvia; Pirtoli, Luigi; Tini, Paolo et al. · 2012 · Journal of cellular biochemistry · DOI

Full title: Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.

Authors: Palumbo, Silvia; Pirtoli, Luigi; Tini, Paolo; Cevenini, Gabriele; Calderaro, Francesco; Toscano, Marzia; Miracco, Clelia; Comincini, Sergio

Year: 2012

Venue: Journal of cellular biochemistry

DOI: https://doi.org/10.1002/jcb.24102

Paper SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Autophagic Flux.

Hu, Wentao; Liu, Xi; Wang, Shang et al. · 2019 · IUBMB life · DOI

Full title: SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Autophagic Flux.

Authors: Hu, Wentao; Liu, Xi; Wang, Shang; Sun, Guifang; Zhao, Ran; Lu, Hong

Year: 2019

Venue: IUBMB life

DOI: https://doi.org/10.1002/iub.1951

Paper Amino acids stimulate glycyl-tRNA synthetase nuclear localization for mammalian target of rapamycin expression in bovine mammary epithelial cells.

Yu, Mengmeng; Luo, Chaochao; Huang, Xin et al. · 2019 · Journal of cellular physiology · DOI

Full title: Amino acids stimulate glycyl-tRNA synthetase nuclear localization for mammalian target of rapamycin expression in bovine mammary epithelial cells.

Authors: Yu, Mengmeng; Luo, Chaochao; Huang, Xin; Chen, Dongying; Li, Shanshan; Qi, Hao; Gao, Xuejun

Year: 2019

Venue: Journal of cellular physiology

DOI: https://doi.org/10.1002/jcp.27523

Paper Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers

Mondal, Susmita; Roy, Debarshi; Bhattacharya, Sayantani Sarkar et al. · 2018 · International Journal of Cancer · DOI

Full title: Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers

Authors: Mondal, Susmita; Roy, Debarshi; Bhattacharya, Sayantani Sarkar; Jin, Ling; Jung, Deok‐Beom; Zhang, Song; Kalogera, Eleftheria; Staub, Julie; Wang, Yaxian; X, Wen; Khurana, Ashwani; Chien, Jeremy; Telang, Sucheta; Chesney, Jason; Tapolsky, Gilles; Petras, Dzeja; Shridhar, Viji

Year: 2018

Venue: International Journal of Cancer

DOI: https://doi.org/10.1002/ijc.31868

Paper Curcumin: A naturally occurring autophagy modulator.

Shakeri, Abolfazl; Cicero, Arrigo F G; Panahi, Yunes et al. · 2019 · Journal of cellular physiology · DOI

Full title: Curcumin: A naturally occurring autophagy modulator.

Authors: Shakeri, Abolfazl; Cicero, Arrigo F G; Panahi, Yunes; Mohajeri, Mohammad; Sahebkar, Amirhossein

Year: 2019

Venue: Journal of cellular physiology

DOI: https://doi.org/10.1002/jcp.27404

Paper Atorvastatin ameliorates LPS-induced inflammatory response by autophagy via AKT/mTOR signaling pathway.

Han, Fei; Xiao, Qing-Qing; Peng, Shi et al. · 2018 · Journal of cellular biochemistry · DOI

Full title: Atorvastatin ameliorates LPS-induced inflammatory response by autophagy via AKT/mTOR signaling pathway.

Authors: Han, Fei; Xiao, Qing-Qing; Peng, Shi; Che, Xin-Yu; Jiang, Li-Sheng; Shao, Qin; He, Ben

Year: 2018

Venue: Journal of cellular biochemistry

DOI: https://doi.org/10.1002/jcb.26320

Paper Downregulation of miRNA-30a enhanced autophagy in osthole-alleviated myocardium ischemia/reperfusion injury.

Liu, Shengzhong; He, Ying; Shi, Jun et al. · 2019 · Journal of cellular physiology · DOI

Full title: Downregulation of miRNA-30a enhanced autophagy in osthole-alleviated myocardium ischemia/reperfusion injury.

Authors: Liu, Shengzhong; He, Ying; Shi, Jun; Liu, Lulu; Ma, Hao; He, Li; Guo, Yingqiang

Year: 2019

Venue: Journal of cellular physiology

DOI: https://doi.org/10.1002/jcp.28556

Paper The Multifaceted Influence of Beta-Hydroxybutyrate on Autophagy, Mitochondrial Metabolism, and Epigenetic Regulation.

Ehtiati, Sajad; Hatami, Behzad; Khatami, Seyyed Hossein et al. · 2025 · Journal of cellular biochemistry · DOI

Full title: The Multifaceted Influence of Beta-Hydroxybutyrate on Autophagy, Mitochondrial Metabolism, and Epigenetic Regulation.

Authors: Ehtiati, Sajad; Hatami, Behzad; Khatami, Seyyed Hossein; Tajernarenj, Kiarash; Abdi, Saeed; Sirati-Sabet, Majid; Ghazizadeh Hashemi, Seyyed Amir Hossein; Ahmadzade, Reyhane; Hamed, Nastran; Goudarzi, Marziyeh; Namvarjah, Fatemeh; Hajimohammadebrahim-Ketabforoush, Melika; Tafakhori, Abbas; Aghamollaii, Vajiheh; Karima, Saeed

Year: 2025

Venue: Journal of cellular biochemistry

DOI: https://doi.org/10.1002/jcb.70050

Paper Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.

Guo, Lanmin; Jiang, Zhi-Mei; Zhan, Yu-Jun et al. · 2023 · Journal of cellular physiology · DOI

Full title: Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.

Authors: Guo, Lanmin; Jiang, Zhi-Mei; Zhan, Yu-Jun; Pan, Wei; Wu, Qing-Wei; Song, Fan-Xu; Zhou, Xue; Zhou, Xin-Yu; Liu, Li-Jun; Wang, Jing-Tao

Year: 2023

Venue: Journal of cellular physiology

DOI: https://doi.org/10.1002/jcp.31010

Paper Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?

Cai, Zhiyou; Zhao, Bin; Li, Keshen et al. · 2012 · Journal of neuroscience research · DOI

Full title: Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?

Authors: Cai, Zhiyou; Zhao, Bin; Li, Keshen; Zhang, Liangqing; Li, Chunhua; Quazi, Sohel H; Tan, Yan

Year: 2012

Venue: Journal of neuroscience research

DOI: https://doi.org/10.1002/jnr.23011

Paper Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR-Dependent Autophagy in the Contralateral Dentate Nucleus.

Wang, Chuan-Jie; Yu, Ke-Wei; Wu, Jun-Fa et al. · 2026 · The Kaohsiung journal of medical sciences · DOI

Full title: Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR-Dependent Autophagy in the Contralateral Dentate Nucleus.

Authors: Wang, Chuan-Jie; Yu, Ke-Wei; Wu, Jun-Fa; Tao, Feng

Year: 2026

Venue: The Kaohsiung journal of medical sciences

DOI: https://doi.org/10.1002/kjm2.70167

Paper Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Kuang, Yaoyun; Zheng, Xuan; Zhang, Lin et al. · 2020 · Journal of Extracellular Vesicles · DOI

Full title: Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Authors: Kuang, Yaoyun; Zheng, Xuan; Zhang, Lin; Ai, Xiaoyu; Venkataramani, Vivek; Kılıç, Ertuğrul; Hermann, Dirk M.; Majid, Arshad; Bähr, Mathias; Doeppner, Thorsten R.

Year: 2020

Venue: Journal of Extracellular Vesicles

DOI: https://doi.org/10.1002/jev2.12024

Paper Oroxylin A induces autophagy in human malignant glioma cells via the mTOR-STAT3-Notch signaling pathway.

Zou, Meijuan; Hu, Chen; You, Qidong et al. · 2015 · Molecular carcinogenesis · DOI

Full title: Oroxylin A induces autophagy in human malignant glioma cells via the mTOR-STAT3-Notch signaling pathway.

Authors: Zou, Meijuan; Hu, Chen; You, Qidong; Zhang, Aixia; Wang, Xuerong; Guo, Qinglong

Year: 2015

Venue: Molecular carcinogenesis

DOI: https://doi.org/10.1002/mc.22212

Paper The burgeoning field of innate immune-mediated disease and autoinflammation.

Peckham, Daniel; Scambler, Thomas; Savic, Sinisa et al. · 2017 · The Journal of pathology · DOI

Full title: The burgeoning field of innate immune-mediated disease and autoinflammation.

Authors: Peckham, Daniel; Scambler, Thomas; Savic, Sinisa; McDermott, Michael F

Year: 2017

Venue: The Journal of pathology

DOI: https://doi.org/10.1002/path.4812

Paper Quinoa Polyphenols Alleviate Glucose Deprivation-Induced Endoplasmic Reticulum Stress by Enhancing Hepatic Cellular Autophagy and Antioxidant Capacity.

Gao, Qiang; Fan, Mingcong; Qian, Haifeng et al. · 2025 · Molecular nutrition & food research · DOI

Full title: Quinoa Polyphenols Alleviate Glucose Deprivation-Induced Endoplasmic Reticulum Stress by Enhancing Hepatic Cellular Autophagy and Antioxidant Capacity.

Authors: Gao, Qiang; Fan, Mingcong; Qian, Haifeng; Li, Yan; Wang, Li

Year: 2025

Venue: Molecular nutrition & food research

DOI: https://doi.org/10.1002/mnfr.70279

Paper Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting

Anton, Stephen D.; Moehl, Keelin; Donahoo, William T. et al. · 2017 · Obesity · DOI

Full title: Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting

Authors: Anton, Stephen D.; Moehl, Keelin; Donahoo, William T.; Marosi, Krisztina; Lee, Stephanie A.; Mainous, Arch G.; Leeuwenburgh, Christiaan; Mattson, Mark P.

Year: 2017

Venue: Obesity

DOI: https://doi.org/10.1002/oby.22065

Paper Targeted Therapies for Parkinson's Disease: From Genetics to the Clinic

Sardi, S. Pablo; Cedarbaum, Jesse M.; Brundin, Patrik · 2018 · Movement Disorders · DOI

Full title: Targeted Therapies for Parkinson's Disease: From Genetics to the Clinic

Authors: Sardi, S. Pablo; Cedarbaum, Jesse M.; Brundin, Patrik

Year: 2018

Venue: Movement Disorders

DOI: https://doi.org/10.1002/mds.27414

Paper mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.

Park, Yun Sun; Park, Jae Hyeon; Ko, Juyeon et al. · 2017 · Environmental toxicology · DOI

Full title: mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.

Authors: Park, Yun Sun; Park, Jae Hyeon; Ko, Juyeon; Shin, In Chul; Koh, Hyun Chul

Year: 2017

Venue: Environmental toxicology

DOI: https://doi.org/10.1002/tox.22216

Paper pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment.

Lin, Yao-Xin; Wang, Yi; Qiao, Sheng-Lin et al. · 2016 · Small (Weinheim an der Bergstrasse, Germany) · DOI

Full title: pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment.

Authors: Lin, Yao-Xin; Wang, Yi; Qiao, Sheng-Lin; An, Hong-Wei; Zhang, Ruo-Xin; Qiao, Zeng-Ying; Rajapaksha, R P Y J; Wang, Lei; Wang, Hao

Year: 2016

Venue: Small (Weinheim an der Bergstrasse, Germany)

DOI: https://doi.org/10.1002/smll.201503709

Paper Conditioned medium of mesenchymal stem cells delays osteoarthritis progression in a rat model by protecting subchondral bone, maintaining matrix homeostasis, and enhancing autophagy.

Chen, Wenbo; Sun, Yaying; Gu, Xueping et al. · 2019 · Journal of tissue engineering and regenerative medicine · DOI

Full title: Conditioned medium of mesenchymal stem cells delays osteoarthritis progression in a rat model by protecting subchondral bone, maintaining matrix homeostasis, and enhancing autophagy.

Authors: Chen, Wenbo; Sun, Yaying; Gu, Xueping; Hao, Yuefeng; Liu, Xingwang; Lin, Jinrong; Chen, Jiwu; Chen, Shiyi

Year: 2019

Venue: Journal of tissue engineering and regenerative medicine

DOI: https://doi.org/10.1002/term.2916

Paper Ginsenoside Rg1 suppresses paraquat-induced epithelial cell senescence by enhancing autophagy in an ATG12-dependent manner.

Huang, Changbao; Xue, Xiang; Gong, Nengkai et al. · 2022 · Environmental toxicology · DOI

Full title: Ginsenoside Rg1 suppresses paraquat-induced epithelial cell senescence by enhancing autophagy in an ATG12-dependent manner.

Authors: Huang, Changbao; Xue, Xiang; Gong, Nengkai; Jiang, Jinghan

Year: 2022

Venue: Environmental toxicology

DOI: https://doi.org/10.1002/tox.23597

Paper A Preview of Selected Articles

Stuart P. Atkinson · 2020 · Stem Cells Translational Medicine · DOI

Full title: A Preview of Selected Articles

Authors: Stuart P. Atkinson

Year: 2020

Venue: Stem Cells Translational Medicine

DOI: https://doi.org/10.1002/sctm.20-0135

Paper Hepatoprotective Effect of Trehalose: Insight into Its Mechanisms of Action.

Forouzanfar, Fatemeh; Guest, Paul C; Jamialahmadi, Tannaz et al. · 2021 · Advances in experimental medicine and biology · DOI

Full title: Hepatoprotective Effect of Trehalose: Insight into Its Mechanisms of Action.

Authors: Forouzanfar, Fatemeh; Guest, Paul C; Jamialahmadi, Tannaz; Sahebkar, Amirhossein

Year: 2021

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-030-73234-9_34

Paper Role of TFEB in Diseases Associated with Lysosomal Dysfunction.

Pan, Hsuan-Yeh; Valapala, Mallika · 2023 · Advances in experimental medicine and biology · DOI

Full title: Role of TFEB in Diseases Associated with Lysosomal Dysfunction.

Authors: Pan, Hsuan-Yeh; Valapala, Mallika

Year: 2023

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-031-27681-1_46

Paper Autophagy and Mitochondrial Encephalomyopathies.

Zhang, Xiangnan; Zheng, Yanrong; Chen, Zhong · 2020 · Advances in experimental medicine and biology · DOI

Full title: Autophagy and Mitochondrial Encephalomyopathies.

Authors: Zhang, Xiangnan; Zheng, Yanrong; Chen, Zhong

Year: 2020

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-981-15-4272-5_6

Paper Alzheimer's disease drug development pipeline: 2022

Cummings, Jeffrey L.; Lee, Garam; Nahed, Pouyan et al. · 2022 · Alzheimer s & Dementia Translational Research & Clinical Interventions · DOI

Full title: Alzheimer's disease drug development pipeline: 2022

Authors: Cummings, Jeffrey L.; Lee, Garam; Nahed, Pouyan; Kambar, Mina Esmail Zadeh Nojoo; Zhong, Kate; Cacho, Jorge Ramón Fonseca; Taghva, Kazem

Year: 2022

Venue: Alzheimer s & Dementia Translational Research & Clinical Interventions

DOI: https://doi.org/10.1002/trc2.12295

Paper Alzheimer's disease drug development pipeline: 2024

Cummings, Jeffrey L.; Zhou, Yadi; Lee, Garam et al. · 2024 · Alzheimer s & Dementia Translational Research & Clinical Interventions · DOI

Full title: Alzheimer's disease drug development pipeline: 2024

Authors: Cummings, Jeffrey L.; Zhou, Yadi; Lee, Garam; Zhong, Kate; Cacho, Jorge Ramón Fonseca; Cheng, Feixiong

Year: 2024

Venue: Alzheimer s & Dementia Translational Research & Clinical Interventions

DOI: https://doi.org/10.1002/trc2.12465

Paper Molecular insights into irisin's role in the regulation of programmed cell death: mechanisms and therapeutic potential.

Yang, Yang; Pullisaar, Helen; Reseland, Janne Elin et al. · 2025 · Journal of molecular medicine (Berlin, Germany) · DOI

Full title: Molecular insights into irisin's role in the regulation of programmed cell death: mechanisms and therapeutic potential.

Authors: Yang, Yang; Pullisaar, Helen; Reseland, Janne Elin; Ma, Jingzhi

Year: 2025

Venue: Journal of molecular medicine (Berlin, Germany)

DOI: https://doi.org/10.1007/s00109-025-02623-z

Paper Lycium barbarum polysaccharide relieves diabetes mellitus-induced cataract by activating Sirtuin 6.

Guo, Yu; Zhou, Yue; Cai, Lianjun et al. · 2026 · International journal of biological macromolecules · DOI

Full title: Lycium barbarum polysaccharide relieves diabetes mellitus-induced cataract by activating Sirtuin 6.

Authors: Guo, Yu; Zhou, Yue; Cai, Lianjun; Fu, Dengdi; Bai, Wenfan; Luo, Mingxiu; Xu, Yanping; Lu, Xiaohong; Yang, Yanhui; Pan, Yan; Yao, Qing

Year: 2026

Venue: International journal of biological macromolecules

DOI: https://doi.org/10.1016/j.ijbiomac.2025.149829

Paper MicroRNA-146a-5p alleviates the pathogenesis of osteoarthritis by inhibiting SDF-1/CXCR4-induced chondrocyte autophagy.

Yang, Tengyun; Li, Canzhang; Li, Yanlin et al. · 2023 · International immunopharmacology · DOI

Full title: MicroRNA-146a-5p alleviates the pathogenesis of osteoarthritis by inhibiting SDF-1/CXCR4-induced chondrocyte autophagy.

Authors: Yang, Tengyun; Li, Canzhang; Li, Yanlin; Cai, Guofeng; Wang, Guoliang; He, Lu; He, Chuan

Year: 2023

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.109938

Paper Expression of miRNA-155 in carotid atherosclerotic plaques of apolipoprotein E knockout (ApoE-/-) mice and the interventional effect of rapamycin.

Ma, Juanjuan; Yang, Shaonan; Ma, Aijun et al. · 2017 · International immunopharmacology · DOI

Full title: Expression of miRNA-155 in carotid atherosclerotic plaques of apolipoprotein E knockout (ApoE-/-) mice and the interventional effect of rapamycin.

Authors: Ma, Juanjuan; Yang, Shaonan; Ma, Aijun; Pan, Xudong; Wang, Hongliang; Li, Na; Liu, Shihai; Wu, Mei

Year: 2017

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2017.02.026

Paper The neuroprotection of progesterone against Aβ-induced NLRP3-Caspase-1 inflammasome activation via enhancing autophagy in astrocytes.

Hong, Yang; Liu, Yunjiang; Yu, Dongzhen et al. · 2019 · International immunopharmacology · DOI

Full title: The neuroprotection of progesterone against Aβ-induced NLRP3-Caspase-1 inflammasome activation via enhancing autophagy in astrocytes.

Authors: Hong, Yang; Liu, Yunjiang; Yu, Dongzhen; Wang, Mingxia; Hou, Yanning

Year: 2019

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2019.05.054

Paper Mechanistic target of rapamycin-mediated autophagy is involved in the alleviation of lipopolysaccharide-induced acute lung injury in rats.

Qin, Li; Li, Min; Tan, Hong-Ling et al. · 2020 · International immunopharmacology · DOI

Full title: Mechanistic target of rapamycin-mediated autophagy is involved in the alleviation of lipopolysaccharide-induced acute lung injury in rats.

Authors: Qin, Li; Li, Min; Tan, Hong-Ling; Yang, Hong-Xing; Li, Shao-Dan; Luan, Zhen-Xian; Chen, Ying-Fan; Yang, Ming-Hui

Year: 2020

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2019.105790

Paper Involvement of melatonin in autophagy-mediated mouse hepatoma H22 cell survival.

Liu, Chang; Jia, Zhiling; Zhang, Xia et al. · 2012 · International immunopharmacology · DOI

Full title: Involvement of melatonin in autophagy-mediated mouse hepatoma H22 cell survival.

Authors: Liu, Chang; Jia, Zhiling; Zhang, Xia; Hou, Jincai; Wang, Li; Hao, Shuling; Ruan, Xinjian; Yu, Zhonghe; Zheng, Yongqiu

Year: 2012

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2011.12.012

Paper The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.

Meng, Ziyu; Liu, Xiaohuan; Li, Ting et al. · 2021 · International immunopharmacology · DOI

Full title: The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.

Authors: Meng, Ziyu; Liu, Xiaohuan; Li, Ting; Fang, Ting; Cheng, Ying; Han, Liping; Sun, Bei; Chen, Liming

Year: 2021

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2021.107492

Paper Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sepsis.

Cui, Shu-Nan; Chen, Zhao-Yuan; Yang, Xiao-Bo et al. · 2019 · International immunopharmacology · DOI

Full title: Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sepsis.

Authors: Cui, Shu-Nan; Chen, Zhao-Yuan; Yang, Xiao-Bo; Chen, Lin; Yang, Yi-Yi; Pan, Shang-Wen; Wang, Ya-Xin; Xu, Ji-Qian; Zhou, Ting; Xiao, Hai-Rong; Qin, Lu; Yuan, Shi-Ying; Shang, You

Year: 2019

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2019.105973

Paper TSP-1 increases autophagy level in cartilage by upregulating HSP27 which delays progression of osteoarthritis.

Li, Haoqian; Huang, Lingan; Zhao, Ruipeng et al. · 2024 · International immunopharmacology · DOI

Full title: TSP-1 increases autophagy level in cartilage by upregulating HSP27 which delays progression of osteoarthritis.

Authors: Li, Haoqian; Huang, Lingan; Zhao, Ruipeng; Wu, Gaige; Yin, Yukun; Zhang, Chengming; Li, Pengcui; Guo, Li; Wei, Xiaochun; Che, Xianda; Li, Lu

Year: 2024

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.111475

Paper miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.

Gao, Xu; Gao, Long-Fei; Zhang, Zhen-Yu et al. · 2024 · International immunopharmacology · DOI

Full title: miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.

Authors: Gao, Xu; Gao, Long-Fei; Zhang, Zhen-Yu; Jia, Shu; Meng, Chun-Yang

Year: 2024

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2023.111331

Paper Sirt1 alleviates osteoarthritis via promoting FoxO1 nucleo-cytoplasm shuttling to facilitate autophagy.

Xu, Mao; Qian, Zhuang; Zhang, Ying et al. · 2024 · International immunopharmacology · DOI

Full title: Sirt1 alleviates osteoarthritis via promoting FoxO1 nucleo-cytoplasm shuttling to facilitate autophagy.

Authors: Xu, Mao; Qian, Zhuang; Zhang, Ying; Gao, Xin; Ma, Zhengmin; Jin, Xinxin; Wu, Shufang

Year: 2024

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2024.111893

Paper Liver X receptor agonist RGX-104 attenuates PHMG-induced pulmonary fibrosis by restoring autophagy-lysosome fusion and suppressing macrophage foaming.

Yan, Zhijiao; Li, Yanting; Ding, Yuchao et al. · 2025 · International immunopharmacology · DOI

Full title: Liver X receptor agonist RGX-104 attenuates PHMG-induced pulmonary fibrosis by restoring autophagy-lysosome fusion and suppressing macrophage foaming.

Authors: Yan, Zhijiao; Li, Yanting; Ding, Yuchao; Sun, Jiaxing; Wang, Hongmei; Xu, Wenjuan; Ding, Xiaoqian; Zhang, Jianzhong; Zhang, Wanjun; Tang, Jinglong; Ji, Xiaoya; Ren, Dunqiang

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.115746

Paper HNRNPA1 promotes TRIM37 mRNA stability and mediates TRAF6 ubiquitination to alleviate osteoarthritis.

Deng, Hailin; Liu, Wanlan; Xiang, Liang et al. · 2025 · International immunopharmacology · DOI

Full title: HNRNPA1 promotes TRIM37 mRNA stability and mediates TRAF6 ubiquitination to alleviate osteoarthritis.

Authors: Deng, Hailin; Liu, Wanlan; Xiang, Liang; Wu, Junxing

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.115568

Paper Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.

Evans, Sarah; Ma, Xiucui; Wang, Xiqiang et al. · 2022 · JACC. Basic to translational science · DOI

Full title: Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.

Authors: Evans, Sarah; Ma, Xiucui; Wang, Xiqiang; Chen, Yana; Zhao, Chen; Weinheimer, Carla J; Kovacs, Attila; Finck, Brian; Diwan, Abhinav; Mann, Douglas L

Year: 2022

Venue: JACC. Basic to translational science

DOI: https://doi.org/10.1016/j.jacbts.2022.06.003

Paper Aberrant STING activation promotes macrophage senescence by suppressing autophagy in vascular aging from diabetes.

Ding, Huiqing; Zhang, Quan; Yang, Rukai et al. · 2025 · iScience · DOI

Full title: Aberrant STING activation promotes macrophage senescence by suppressing autophagy in vascular aging from diabetes.

Authors: Ding, Huiqing; Zhang, Quan; Yang, Rukai; Fu, Liyao; Jiang, Hejun; Zhu, Qingyi; Tai, Shi

Year: 2025

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2024.111594

Paper Melatonin ameliorates sepsis-induced myocardial dysfunction by promoting autophagy via SIRT1-mediated TFEB deacetylation.

Ge, Yixin; Li, Min; Wang, Bo et al. · 2026 · International immunopharmacology · DOI

Full title: Melatonin ameliorates sepsis-induced myocardial dysfunction by promoting autophagy via SIRT1-mediated TFEB deacetylation.

Authors: Ge, Yixin; Li, Min; Wang, Bo; Zhang, Yingnan; Zhou, Xiaoxian; Zhang, Yidan; Li, Tong; Li, Yue; Fang, Shaohong; Liu, Wenhua

Year: 2026

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.116098

Paper Jiedu Tongluo Baoshen formula enhances podocyte autophagy and reduces proteinuria in diabetic kidney disease by inhibiting PI3K/Akt/mTOR signaling pathway.

Jin, Di; Liu, Feng; Yu, Miao et al. · 2022 · Journal of ethnopharmacology · DOI

Full title: Jiedu Tongluo Baoshen formula enhances podocyte autophagy and reduces proteinuria in diabetic kidney disease by inhibiting PI3K/Akt/mTOR signaling pathway.

Authors: Jin, Di; Liu, Feng; Yu, Miao; Zhao, Yunyun; Yan, Guanchi; Xue, Jiaojiao; Sun, Yuting; Zhao, Daqing; Li, Xiangyan; Qi, Wenxiu; Wang, Xiuge

Year: 2022

Venue: Journal of ethnopharmacology

DOI: https://doi.org/10.1016/j.jep.2022.115246

Paper Sertad1 is elevated and plays a necessary role in neuron loss and cognitive impairment in a mouse model of Alzheimer's disease.

Ambareen, Naqiya; Gharami, Kusumika; Mondal, Ananya et al. · 2025 · The Journal of biological chemistry · DOI

Full title: Sertad1 is elevated and plays a necessary role in neuron loss and cognitive impairment in a mouse model of Alzheimer's disease.

Authors: Ambareen, Naqiya; Gharami, Kusumika; Mondal, Ananya; Sarkar, Uday Aditya; Biswas, Subhas C

Year: 2025

Venue: The Journal of biological chemistry

DOI: https://doi.org/10.1016/j.jbc.2025.110875

Paper Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice.

Su, Pan; Wu, Mengdi; Yin, Xiaoting et al. · 2023 · Journal of ethnopharmacology · DOI

Full title: Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice.

Authors: Su, Pan; Wu, Mengdi; Yin, Xiaoting; Li, Mengyuan; Li, Yucheng; Bai, Ming; Wang, Baoying; Xu, Erping

Year: 2023

Venue: Journal of ethnopharmacology

DOI: https://doi.org/10.1016/j.jep.2023.116659

Paper Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy.

Cao, Jianwen; Tang, Cheng; Gao, Manman et al. · 2020 · Journal of ethnopharmacology · DOI

Full title: Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy.

Authors: Cao, Jianwen; Tang, Cheng; Gao, Manman; Rui, Yanggang; Zhang, Jie; Wang, Li; Wang, Yang; Xu, Bo; Yan, Bing Chun

Year: 2020

Venue: Journal of ethnopharmacology

DOI: https://doi.org/10.1016/j.jep.2020.112884

Paper Fufang zhenzhu tiaozhi capsule alleviates hypothalamic endoplasmic reticulum stress and leptin resistance through autophagy modulation in DIO rats.

Hua, Tingyu; Wu, Qiwen; Huang, Zhang et al. · 2025 · Journal of ethnopharmacology · DOI

Full title: Fufang zhenzhu tiaozhi capsule alleviates hypothalamic endoplasmic reticulum stress and leptin resistance through autophagy modulation in DIO rats.

Authors: Hua, Tingyu; Wu, Qiwen; Huang, Zhang; Cai, Jinyan

Year: 2025

Venue: Journal of ethnopharmacology

DOI: https://doi.org/10.1016/j.jep.2025.120056

Paper Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the mitophagy level of granulosa cells in mice.

Huang, Pan; Zhou, Yan; Tang, Weihong et al. · 2022 · The Journal of nutritional biochemistry · DOI

Full title: Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the mitophagy level of granulosa cells in mice.

Authors: Huang, Pan; Zhou, Yan; Tang, Weihong; Ren, Caifang; Jiang, Anqi; Wang, Xuxin; Qian, Xin; Zhou, Zhengrong; Gong, Aihua

Year: 2022

Venue: The Journal of nutritional biochemistry

DOI: https://doi.org/10.1016/j.jnutbio.2021.108911

Paper Autophagy-enhancing drug carbamazepine diminishes hepatocellular death in fibrinogen storage disease.

Puls, Florian; Goldschmidt, Imeke; Bantel, Heike et al. · 2013 · Journal of hepatology · DOI

Full title: Autophagy-enhancing drug carbamazepine diminishes hepatocellular death in fibrinogen storage disease.

Authors: Puls, Florian; Goldschmidt, Imeke; Bantel, Heike; Agne, Clemens; Bröcker, Verena; Dämmrich, Maximilian; Lehmann, Ulrich; Berrang, Jens; Pfister, Eva-Doreen; Kreipe, Hans Heinrich; Baumann, Ulrich

Year: 2013

Venue: Journal of hepatology

DOI: https://doi.org/10.1016/j.jhep.2013.05.018

Paper Maimendong decoction modulates the PINK1/Parkin signaling pathway alleviates type 2 alveolar epithelial cells senescence and enhances mitochondrial autophagy to offer potential therapeutic effects for idiopathic pulmonary fibrosis.

Zhou, Yuhe; Su, Wen; Xu, Mengzhen et al. · 2025 · Journal of ethnopharmacology · DOI

Full title: Maimendong decoction modulates the PINK1/Parkin signaling pathway alleviates type 2 alveolar epithelial cells senescence and enhances mitochondrial autophagy to offer potential therapeutic effects for idiopathic pulmonary fibrosis.

Authors: Zhou, Yuhe; Su, Wen; Xu, Mengzhen; Zhang, Aijun; Li, Shaoli; Guo, Hong; Gong, Kai; Lu, Kaihui; Yu, Xin; Zhu, Jiang; Zhu, Qingjun; Liu, Chuanguo

Year: 2025

Venue: Journal of ethnopharmacology

DOI: https://doi.org/10.1016/j.jep.2025.119568

Paper MC-LR disrupts dopamine synthesis in the substantia nigra of midbrain by enhancing the chaperone-mediated autophagy pathway through direct binding to ERK2.

Wu, Huifang; Yan, Minghao; Wu, Tong et al. · 2024 · Journal of hazardous materials · DOI

Full title: MC-LR disrupts dopamine synthesis in the substantia nigra of midbrain by enhancing the chaperone-mediated autophagy pathway through direct binding to ERK2.

Authors: Wu, Huifang; Yan, Minghao; Wu, Tong; Han, Xiaodong

Year: 2024

Venue: Journal of hazardous materials

DOI: https://doi.org/10.1016/j.jhazmat.2024.136181

Paper Rosamultin attenuates cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt/mTOR pathway.

Zhang, Hailin; Zhou, Baoyuan; Liu, Jixing et al. · 2025 · Journal of pharmacological sciences · DOI

Full title: Rosamultin attenuates cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt/mTOR pathway.

Authors: Zhang, Hailin; Zhou, Baoyuan; Liu, Jixing; Tang, Bo; Xie, Zongzhi; Li, Jianxiong

Year: 2025

Venue: Journal of pharmacological sciences

DOI: https://doi.org/10.1016/j.jphs.2025.04.001

Paper Paeoniflorin, ferulic acid, and atractylenolide III improved LPS-induced neuroinflammation of BV2 microglia cells by enhancing autophagy.

Zhou, Xiaolan; Chen, Xingru; Cheng, Xiaoqing et al. · 2023 · Journal of pharmacological sciences · DOI

Full title: Paeoniflorin, ferulic acid, and atractylenolide III improved LPS-induced neuroinflammation of BV2 microglia cells by enhancing autophagy.

Authors: Zhou, Xiaolan; Chen, Xingru; Cheng, Xiaoqing; Lin, Liting; Quan, Shijian; Li, Shijun; Zhan, Ruoting; Wu, Qingguang; Liu, Sijun

Year: 2023

Venue: Journal of pharmacological sciences

DOI: https://doi.org/10.1016/j.jphs.2023.04.007

Paper HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: The role of AMP-activated protein kinase.

Xue, Huan; Ji, Yingshi; Wei, Shengnan et al. · 2016 · Life sciences · DOI

Full title: HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: The role of AMP-activated protein kinase.

Authors: Xue, Huan; Ji, Yingshi; Wei, Shengnan; Yu, Yang; Yan, Xin; Liu, Shuping; Zhang, Ming; Yao, Fan; Lan, Xiaoxin; Chen, Li

Year: 2016

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2016.04.004

Paper Antagonism of miR-429 ameliorates anoxia/reoxygenation injury in cardiomyocytes by enhancing MO25/LKB1/AMPK mediated autophagy.

Zhu, Qingqing; Hu, Fangfang · 2019 · Life sciences · DOI

Full title: Antagonism of miR-429 ameliorates anoxia/reoxygenation injury in cardiomyocytes by enhancing MO25/LKB1/AMPK mediated autophagy.

Authors: Zhu, Qingqing; Hu, Fangfang

Year: 2019

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2019.116842

Paper Osteoprotegerin prompts cardiomyocyte hypertrophy via autophagy inhibition mediated by FAK/BECLIN1 pathway.

Zheng, Dezhong; Zhang, Mingyu; Liu, Tingrong et al. · 2021 · Life sciences · DOI

Full title: Osteoprotegerin prompts cardiomyocyte hypertrophy via autophagy inhibition mediated by FAK/BECLIN1 pathway.

Authors: Zheng, Dezhong; Zhang, Mingyu; Liu, Tingrong; Zhou, Tao; Shen, Anna

Year: 2021

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2020.118550

Paper l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity.

Khedr, Naglaa F; Werida, Rehab H · 2022 · Life sciences · DOI

Full title: l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity.

Authors: Khedr, Naglaa F; Werida, Rehab H

Year: 2022

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2021.120025

Paper Curcumin prevents tension-induced endplate cartilage degeneration by enhancing autophagy.

Xiao, Liang; Ding, Baiyang; Gao, Jianming et al. · 2020 · Life sciences · DOI

Full title: Curcumin prevents tension-induced endplate cartilage degeneration by enhancing autophagy.

Authors: Xiao, Liang; Ding, Baiyang; Gao, Jianming; Yang, Bijing; Wang, Jing; Xu, Hongguang

Year: 2020

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2020.118213

Paper Rethinking Parkinson's: The role of proteostasis networks and autophagy in disease progression.

Sharma, Akhil; Mannan, Ashi; Singh, Thakur Gurjeet · 2025 · Molecular and cellular neurosciences · DOI

Full title: Rethinking Parkinson's: The role of proteostasis networks and autophagy in disease progression.

Authors: Sharma, Akhil; Mannan, Ashi; Singh, Thakur Gurjeet

Year: 2025

Venue: Molecular and cellular neurosciences

DOI: https://doi.org/10.1016/j.mcn.2025.104023

Paper Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2.

Lu, Yue; Zhang, Yixian; Lou, Yan et al. · 2020 · Life sciences · DOI

Full title: Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2.

Authors: Lu, Yue; Zhang, Yixian; Lou, Yan; Cui, Wenpeng; Miao, Lining

Year: 2020

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2020.118153

Paper Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq.

Hao, Fengjin; Feng, Yueqin · 2021 · Life sciences · DOI

Full title: Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq.

Authors: Hao, Fengjin; Feng, Yueqin

Year: 2021

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2020.118624

Paper Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway.

Zaki, Eman S; Sayed, Rabab H; Saad, Muhammed A et al. · 2023 · Life sciences · DOI

Full title: Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway.

Authors: Zaki, Eman S; Sayed, Rabab H; Saad, Muhammed A; El-Yamany, Muhammed F

Year: 2023

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2023.121806

Paper Mitochondrial damage and intralysosomal degradation in cellular aging.

Terman, Alexei; Gustafsson, Bertil; Brunk, Ulf T · 2006 · Molecular aspects of medicine · DOI

Full title: Mitochondrial damage and intralysosomal degradation in cellular aging.

Authors: Terman, Alexei; Gustafsson, Bertil; Brunk, Ulf T

Year: 2006

Venue: Molecular aspects of medicine

DOI: https://doi.org/10.1016/j.mam.2006.08.006

Paper LncSSBP1/FOXO3 axis modulates autophagy: a novel insight into bronchial epithelial cells defense against Talaromyces marneffei infection.

Lin, Lu; Pan, Shitong; Xu, Mingpeng et al. · 2025 · Microbes and infection · DOI

Full title: LncSSBP1/FOXO3 axis modulates autophagy: a novel insight into bronchial epithelial cells defense against Talaromyces marneffei infection.

Authors: Lin, Lu; Pan, Shitong; Xu, Mingpeng; Chen, Huan; He, Zhiyi; Li, Yinghua

Year: 2025

Venue: Microbes and infection

DOI: https://doi.org/10.1016/j.micinf.2025.105561

Paper Levels of miR-125a-5p are altered in Mycobacterium avium-infected macrophages and associate with the triggering of an autophagic response.

Wang, Yang; Chen, Cai; Xu, Xiao-Dan et al. · 2020 · Microbes and infection · DOI

Full title: Levels of miR-125a-5p are altered in Mycobacterium avium-infected macrophages and associate with the triggering of an autophagic response.

Authors: Wang, Yang; Chen, Cai; Xu, Xiao-Dan; Li, Hui; Cheng, Ming-Hua; Liu, Jing; Tang, Li-Jun

Year: 2020

Venue: Microbes and infection

DOI: https://doi.org/10.1016/j.micinf.2019.07.002

Paper LPS restores protective immunity in macrophages against Mycobacterium tuberculosis via autophagy.

Fang, Fang; Ge, Qing; Li, Rui et al. · 2020 · Molecular immunology · DOI

Full title: LPS restores protective immunity in macrophages against Mycobacterium tuberculosis via autophagy.

Authors: Fang, Fang; Ge, Qing; Li, Rui; Lv, Jingzhu; Zhang, Yao; Feng, Anlin; Kelly, Gabriel T; Wang, Hongtao; Wang, Xiaojing; Song, Chuanwang; Wang, Ting; Qian, Zhongqing

Year: 2020

Venue: Molecular immunology

DOI: https://doi.org/10.1016/j.molimm.2020.05.001

Paper Autophagy: The missing link in diabetic neuropathy?

Yerra, Veera Ganesh; Gundu, Chayanika; Bachewal, Pragna et al. · 2016 · Medical hypotheses · DOI

Full title: Autophagy: The missing link in diabetic neuropathy?

Authors: Yerra, Veera Ganesh; Gundu, Chayanika; Bachewal, Pragna; Kumar, Ashutosh

Year: 2016

Venue: Medical hypotheses

DOI: https://doi.org/10.1016/j.mehy.2015.11.004

Paper HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome.

Wang, Tingting; Wang, Jingyu; Wang, Jie et al. · 2019 · Neurobiology of disease · DOI

Full title: HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome.

Authors: Wang, Tingting; Wang, Jingyu; Wang, Jie; Mao, Lin; Tang, Bin; Vanderklish, Peter W; Liao, Xun; Xiong, Zhi-Qi; Liao, Lujian

Year: 2019

Venue: Neurobiology of disease

DOI: https://doi.org/10.1016/j.nbd.2019.104585

Paper The multifaceted role of GLP-1 in metabolic disorders, chronic inflammation, and aging: Mechanisms and therapeutic potential.

Li, Mo; Xu, Shenghao; Cai, Hanqing et al. · 2026 · Metabolism: clinical and experimental · DOI

Full title: The multifaceted role of GLP-1 in metabolic disorders, chronic inflammation, and aging: Mechanisms and therapeutic potential.

Authors: Li, Mo; Xu, Shenghao; Cai, Hanqing; Xiao, Jianlin; Qin, Yanguo

Year: 2026

Venue: Metabolism: clinical and experimental

DOI: https://doi.org/10.1016/j.metabol.2026.156547

Paper miR-142-3p alleviates neuronal apoptosis in Parkinson's disease via negatively regulating C9orf72.

Meng, Qinghao; Chen, Jiayu; Liang, Yue et al. · 2024 · Neuroscience letters · DOI

Full title: miR-142-3p alleviates neuronal apoptosis in Parkinson's disease via negatively regulating C9orf72.

Authors: Meng, Qinghao; Chen, Jiayu; Liang, Yue; Zhang, Xilin; Ding, Jianhua; Fang, Yinquan; Hu, Gang

Year: 2024

Venue: Neuroscience letters

DOI: https://doi.org/10.1016/j.neulet.2024.137887

Paper Aspirin restores endothelial function by mitigating 17β-estradiol-induced α-SMA accumulation and autophagy inhibition via Vps15 scaffold regulation of Beclin-1 phosphorylation.

Wu, Hangyu; Wu, Siyang; Zhu, Yingchao et al. · 2020 · Life sciences · DOI

Full title: Aspirin restores endothelial function by mitigating 17β-estradiol-induced α-SMA accumulation and autophagy inhibition via Vps15 scaffold regulation of Beclin-1 phosphorylation.

Authors: Wu, Hangyu; Wu, Siyang; Zhu, Yingchao; Cheng, Jiayi; Ye, Shazhou; Xi, Yang; Huang, Qin; Zhang, Yisheng; Bu, Shizhong

Year: 2020

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2020.118383

Paper GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.

Zhu, Zhongkang; Liu, Yuxi; Li, Xinyun et al. · 2022 · Neuroscience letters · DOI

Full title: GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.

Authors: Zhu, Zhongkang; Liu, Yuxi; Li, Xinyun; Zhang, Lin; Liu, Huihui; Cui, Yong; Wang, Yanjie; Zhao, Danyu

Year: 2022

Venue: Neuroscience letters

DOI: https://doi.org/10.1016/j.neulet.2021.136300

Paper Therapeutic potential of curcumin in autophagy modulation: Insights into the role of transcription factor EB.

Radbakhsh, Shabnam; Kesharwani, Prashant; Sahebkar, Amirhossein · 2024 · Mutation research · DOI

Full title: Therapeutic potential of curcumin in autophagy modulation: Insights into the role of transcription factor EB.

Authors: Radbakhsh, Shabnam; Kesharwani, Prashant; Sahebkar, Amirhossein

Year: 2024

Venue: Mutation research

DOI: https://doi.org/10.1016/j.mrfmmm.2024.111879

Paper Autophagy, aging, and age-related neurodegeneration.

Palmer, Jennifer E; Wilson, Niall; Son, Sung Min et al. · 2025 · Neuron · DOI

Full title: Autophagy, aging, and age-related neurodegeneration.

Authors: Palmer, Jennifer E; Wilson, Niall; Son, Sung Min; Obrocki, Pawel; Wrobel, Lidia; Rob, Matea; Takla, Michael; Korolchuk, Viktor I; Rubinsztein, David C

Year: 2025

Venue: Neuron

DOI: https://doi.org/10.1016/j.neuron.2024.09.015

Paper LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in spinal cord injury.

Liu, Ruoxi; Ye, Jintao; Huang, Sihua · 2025 · Non-coding RNA research · DOI

Full title: LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in spinal cord injury.

Authors: Liu, Ruoxi; Ye, Jintao; Huang, Sihua

Year: 2025

Venue: Non-coding RNA research

DOI: https://doi.org/10.1016/j.ncrna.2025.05.013

Paper Lithium Chloride Facilitates Autophagy Following Spinal Cord Injury via ERK-dependent Pathway.

Liu, Peilin; Zhang, Zijuan; Wang, Qingde et al. · 2017 · Neurotoxicity research · DOI

Full title: Lithium Chloride Facilitates Autophagy Following Spinal Cord Injury via ERK-dependent Pathway.

Authors: Liu, Peilin; Zhang, Zijuan; Wang, Qingde; Guo, Rundong; Mei, Wei

Year: 2017

Venue: Neurotoxicity research

DOI: https://doi.org/10.1007/s12640-017-9758-1

Paper Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease.

Friedman, Lauren G; Qureshi, Yasir H; Yu, Wai Haung · 2015 · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · DOI

Full title: Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease.

Authors: Friedman, Lauren G; Qureshi, Yasir H; Yu, Wai Haung

Year: 2015

Venue: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

DOI: https://doi.org/10.1007/s13311-014-0320-z

Paper TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Scotter, Emma L.; Chen, Han-Jou; Shaw, Christopher E. · 2015 · Neurotherapeutics · DOI

Full title: TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Authors: Scotter, Emma L.; Chen, Han-Jou; Shaw, Christopher E.

Year: 2015

Venue: Neurotherapeutics

DOI: https://doi.org/10.1007/s13311-015-0338-x

Paper Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.

Lin, Ming-Wei; Chen, Yi-Hung; Yang, Han-Ben et al. · 2020 · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · DOI

Full title: Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.

Authors: Lin, Ming-Wei; Chen, Yi-Hung; Yang, Han-Ben; Lin, Chi Chien; Hung, Shih-Ya

Year: 2020

Venue: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

DOI: https://doi.org/10.1007/s13311-019-00803-7

Paper Molecular Targets of Cannabidiol in Neurological Disorders

Bih, Clementino Ibeas; Chen, Tong; Nunn, Alistair V.W. et al. · 2015 · Neurotherapeutics · DOI

Full title: Molecular Targets of Cannabidiol in Neurological Disorders

Authors: Bih, Clementino Ibeas; Chen, Tong; Nunn, Alistair V.W.; Bazelot, Michaël; Dallas, Mark; Whalley, Benjamin J.

Year: 2015

Venue: Neurotherapeutics

DOI: https://doi.org/10.1007/s13311-015-0377-3

Paper Genetics, Mechanisms, and Therapeutic Progress in Polyglutamine Spinocerebellar Ataxias

Buijsen, Ronald A.M.; Toonen, Lodewijk J.A.; Gardiner, Sarah L. et al. · 2019 · Neurotherapeutics · DOI

Full title: Genetics, Mechanisms, and Therapeutic Progress in Polyglutamine Spinocerebellar Ataxias

Authors: Buijsen, Ronald A.M.; Toonen, Lodewijk J.A.; Gardiner, Sarah L.; Roon‐Mom, Willeke van

Year: 2019

Venue: Neurotherapeutics

DOI: https://doi.org/10.1007/s13311-018-00696-y

Paper A Narrative Review about Metabolic Pathways, Molecular Mechanisms and Clinical Implications of Intermittent Fasting as Autophagy Promotor.

Vergara Nieto, Álvaro Andrés; Diaz, Andrés Halabi; Hernández, Millaray et al. · 2025 · Current nutrition reports · DOI

Full title: A Narrative Review about Metabolic Pathways, Molecular Mechanisms and Clinical Implications of Intermittent Fasting as Autophagy Promotor.

Authors: Vergara Nieto, Álvaro Andrés; Diaz, Andrés Halabi; Hernández, Millaray; Sagredo, Daniel

Year: 2025

Venue: Current nutrition reports

DOI: https://doi.org/10.1007/s13668-025-00666-9

Paper Targeting α-Synuclein in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapeutics.

Savitt, Daniel; Jankovic, Joseph · 2019 · Drugs · DOI

Full title: Targeting α-Synuclein in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapeutics.

Authors: Savitt, Daniel; Jankovic, Joseph

Year: 2019

Venue: Drugs

DOI: https://doi.org/10.1007/s40265-019-01104-1

Paper Fisetin promotes ischemic flap survival by enhancing autophagy via inhibition of the PI3K/Akt/mTOR signaling pathway.

Fu, Yuedong; Ye, Chenhao; Xu, Huawei et al. · 2026 · Archives of biochemistry and biophysics · DOI

Full title: Fisetin promotes ischemic flap survival by enhancing autophagy via inhibition of the PI3K/Akt/mTOR signaling pathway.

Authors: Fu, Yuedong; Ye, Chenhao; Xu, Huawei; Zhu, Yingying; Zhou, Wei; Zhou, Kailiang; Li, Zhijie; Qi, Jianjun; Lin, Ping

Year: 2026

Venue: Archives of biochemistry and biophysics

DOI: https://doi.org/10.1016/j.abb.2025.110716

Paper Vascular mimicry: Triggers, molecular interactions and in vivo models.

Wechman, Stephen L; Emdad, Luni; Sarkar, Devanand et al. · 2020 · Advances in cancer research · DOI

Full title: Vascular mimicry: Triggers, molecular interactions and in vivo models.

Authors: Wechman, Stephen L; Emdad, Luni; Sarkar, Devanand; Das, Swadesh K; Fisher, Paul B

Year: 2020

Venue: Advances in cancer research

DOI: https://doi.org/10.1016/bs.acr.2020.06.001

Paper Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

Zhao, Wennan; Qiu, Yuling; Kong, Dexin · 2016 · Acta Pharmaceutica Sinica B · DOI

Full title: Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

Authors: Zhao, Wennan; Qiu, Yuling; Kong, Dexin

Year: 2016

Venue: Acta Pharmaceutica Sinica B

DOI: https://doi.org/10.1016/j.apsb.2016.07.006

Paper Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis.

Li, Yixian; Yang, Peng; Meng, Ran et al. · 2024 · Acta pharmaceutica Sinica. B · DOI

Full title: Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis.

Authors: Li, Yixian; Yang, Peng; Meng, Ran; Xu, Shuting; Zhou, Lingling; Qian, Kang; Wang, Pengzhen; Cheng, Yunlong; Sheng, Dongyu; Xu, Minjun; Wang, Tianying; Wu, Jing; Cao, Jinxu; Zhang, Qizhi

Year: 2024

Venue: Acta pharmaceutica Sinica. B

DOI: https://doi.org/10.1016/j.apsb.2023.10.009

Paper The effect of fasting or calorie restriction on autophagy induction: A review of the literature.

Bagherniya, Mohammad; Butler, Alexandra E; Barreto, George E et al. · 2018 · Ageing research reviews · DOI

Full title: The effect of fasting or calorie restriction on autophagy induction: A review of the literature.

Authors: Bagherniya, Mohammad; Butler, Alexandra E; Barreto, George E; Sahebkar, Amirhossein

Year: 2018

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2018.08.004

Paper Enhancement of oligodendrocyte autophagy alleviates white matter injury and cognitive impairment induced by chronic cerebral hypoperfusion in rats.

Wang, Huiyang; Liu, Yueyang; Guo, Zhenkun et al. · 2023 · Acta pharmaceutica Sinica. B · DOI

Full title: Enhancement of oligodendrocyte autophagy alleviates white matter injury and cognitive impairment induced by chronic cerebral hypoperfusion in rats.

Authors: Wang, Huiyang; Liu, Yueyang; Guo, Zhenkun; Cui, Minghui; Pang, Peng; Yang, Jingyu; Wu, Chunfu

Year: 2023

Venue: Acta pharmaceutica Sinica. B

DOI: https://doi.org/10.1016/j.apsb.2023.03.014

Paper Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.

Dong, Yunxian; Cao, Xiaoling; Huang, Jinsheng et al. · 2024 · Biochimica et biophysica acta. Molecular basis of disease · DOI

Full title: Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.

Authors: Dong, Yunxian; Cao, Xiaoling; Huang, Jinsheng; Hu, Zhicheng; Chen, Chufen; Chen, Miao; Long, Qian; Xu, Zhongye; Lv, Dongming; Rong, Yanchao; Luo, Shengkang; Wang, Haibin; Deng, Wuguo; Tang, Bing

Year: 2024

Venue: Biochimica et biophysica acta. Molecular basis of disease

DOI: https://doi.org/10.1016/j.bbadis.2023.166887

Paper TRIM50 regulates Beclin 1 proautophagic activity.

Fusco, Carmela; Mandriani, Barbara; Di Rienzo, Martina et al. · 2018 · Biochimica et biophysica acta. Molecular cell research · DOI

Full title: TRIM50 regulates Beclin 1 proautophagic activity.

Authors: Fusco, Carmela; Mandriani, Barbara; Di Rienzo, Martina; Micale, Lucia; Malerba, Natascia; Cocciadiferro, Dario; Sjøttem, Eva; Augello, Bartolomeo; Squeo, Gabriella Maria; Pellico, Maria Teresa; Jain, Ashish; Johansen, Terje; Fimia, Gian Maria; Merla, Giuseppe

Year: 2018

Venue: Biochimica et biophysica acta. Molecular cell research

DOI: https://doi.org/10.1016/j.bbamcr.2018.03.011

Paper REDD1 attenuates cardiac hypertrophy via enhancing autophagy.

Liu, Chen; Xue, Ruicong; Wu, Dexi et al. · 2014 · Biochemical and biophysical research communications · DOI

Full title: REDD1 attenuates cardiac hypertrophy via enhancing autophagy.

Authors: Liu, Chen; Xue, Ruicong; Wu, Dexi; Wu, Lingling; Chen, Cong; Tan, Weiping; Chen, Yili; Dong, Yugang

Year: 2014

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2014.10.079

Paper Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.

Qin, Yue; Qiu, Jingru; Wang, Ping et al. · 2021 · Brain, behavior, and immunity · DOI

Full title: Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.

Authors: Qin, Yue; Qiu, Jingru; Wang, Ping; Liu, Jia; Zhao, Yong; Jiang, Fan; Lou, Haiyan

Year: 2021

Venue: Brain, behavior, and immunity

DOI: https://doi.org/10.1016/j.bbi.2020.10.010

Paper MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats.

Feng, Laipeng; Wang, Huiying; Chen, Chen et al. · 2024 · Behavioural brain research · DOI

Full title: MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats.

Authors: Feng, Laipeng; Wang, Huiying; Chen, Chen; Fu, Jiacheng; Zhao, Liqin; Zhao, Xia; Geng, Mengjun; Ren, Mengdi; Tong, Lidan; Li, Yan; Gu, Jingyang; Wang, Changhong

Year: 2024

Venue: Behavioural brain research

DOI: https://doi.org/10.1016/j.bbr.2024.114962

Paper Immunoblot-based assays for assessing autophagy in the turquoise killifish Nothobranchius furzeri.

Anagnostopoulos, Gerasimos; Montégut, Léa; Chen, Hui et al. · 2021 · Methods in cell biology · DOI

Full title: Immunoblot-based assays for assessing autophagy in the turquoise killifish Nothobranchius furzeri.

Authors: Anagnostopoulos, Gerasimos; Montégut, Léa; Chen, Hui; Carbonnier, Vincent; Martins, Isabelle; Mangane, Khady; Mannioui, Abdelkrim; Bois, Alex; Baracco, Elisa Elena; Maiuri, Maria Chiara; Kroemer, Guido

Year: 2021

Venue: Methods in cell biology

DOI: https://doi.org/10.1016/bs.mcb.2020.10.007

Paper Ginsenoside Rg3 improves cardiac mitochondrial population quality: mimetic exercise training.

Sun, Mengwei; Huang, Chenglin; Wang, Cheng et al. · 2013 · Biochemical and biophysical research communications · DOI

Full title: Ginsenoside Rg3 improves cardiac mitochondrial population quality: mimetic exercise training.

Authors: Sun, Mengwei; Huang, Chenglin; Wang, Cheng; Zheng, Jianheng; Zhang, Peng; Xu, Yangshu; Chen, Hong; Shen, Weili

Year: 2013

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2013.10.039

Paper Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.

Wu, Han; Feng, Ke; Zhang, Chao et al. · 2021 · Biochemical and biophysical research communications · DOI

Full title: Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.

Authors: Wu, Han; Feng, Ke; Zhang, Chao; Zhang, Hao; Zhang, Jing; Hua, Yunqing; Dong, Zhengwei; Zhu, Yaxian; Yang, Shu; Ma, Chuanrui

Year: 2021

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2021.04.029

Paper GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.

He, Qin; Sha, Sha; Sun, Lei et al. · 2016 · Biochemical and biophysical research communications · DOI

Full title: GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.

Authors: He, Qin; Sha, Sha; Sun, Lei; Zhang, Jing; Dong, Ming

Year: 2016

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2016.05.086

Paper PVT1 alleviates hypoxia-induced endothelial apoptosis by enhancing autophagy via the miR-15b-5p/ATG14 and miR-424-5p/ATG14 axis.

Zhang, Ping; Gong, Shenghui; Li, Shuoshuo et al. · 2023 · Biochemical and biophysical research communications · DOI

Full title: PVT1 alleviates hypoxia-induced endothelial apoptosis by enhancing autophagy via the miR-15b-5p/ATG14 and miR-424-5p/ATG14 axis.

Authors: Zhang, Ping; Gong, Shenghui; Li, Shuoshuo; Yuan, Zengqiang

Year: 2023

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2023.06.001

Paper Psychological stress induces hair regenerative disorders through corticotropin-releasing hormone-mediated autophagy inhibition.

Liang, Wenzi; Zhao, Yinglin; Cai, Bozhi et al. · 2024 · Biochemical and biophysical research communications · DOI

Full title: Psychological stress induces hair regenerative disorders through corticotropin-releasing hormone-mediated autophagy inhibition.

Authors: Liang, Wenzi; Zhao, Yinglin; Cai, Bozhi; Huang, Yuxin; Chen, Xiuwen; Ni, Na; Wang, Yingshan; Lin, Zhaoping; Lin, Changmin; Huang, Keng

Year: 2024

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2024.149564

Paper 2-Methoxyestradiol protects against ischemia/reperfusion injury in alcoholic fatty liver by enhancing sirtuin 1-mediated autophagy.

Cho, Hong-Ik; Seo, Min-Jong; Lee, Sun-Mee · 2017 · Biochemical pharmacology · DOI

Full title: 2-Methoxyestradiol protects against ischemia/reperfusion injury in alcoholic fatty liver by enhancing sirtuin 1-mediated autophagy.

Authors: Cho, Hong-Ik; Seo, Min-Jong; Lee, Sun-Mee

Year: 2017

Venue: Biochemical pharmacology

DOI: https://doi.org/10.1016/j.bcp.2017.02.008

Paper 5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma.

Fredericks, Kim; Kriel, Jurgen; Engelbrecht, Lize et al. · 2024 · Biochemistry and biophysics reports · DOI

Full title: 5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma.

Authors: Fredericks, Kim; Kriel, Jurgen; Engelbrecht, Lize; Mercea, Petra Andreea; Widhalm, Georg; Harrington, Brad; Vlok, Ian; Loos, Ben

Year: 2024

Venue: Biochemistry and biophysics reports

DOI: https://doi.org/10.1016/j.bbrep.2024.101642

Paper Streptooctatin A induces autophagy and promotes α-synuclein clearance by directly binding to SUMO2 and inhibiting SUMOylation.

Roh, Jongtae; Jang, Jun-Pil; Kim, Gun-Hee et al. · 2025 · Biochemical pharmacology · DOI

Full title: Streptooctatin A induces autophagy and promotes α-synuclein clearance by directly binding to SUMO2 and inhibiting SUMOylation.

Authors: Roh, Jongtae; Jang, Jun-Pil; Kim, Gun-Hee; Jang, Mina; Park, Jihun; Oh, Taehoon; Kwon, Yong-Jun; Ahn, Jong Seog; Jang, Jae-Hyuk; Ko, Sung-Kyun

Year: 2025

Venue: Biochemical pharmacology

DOI: https://doi.org/10.1016/j.bcp.2025.117195

Paper Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease.

Xu, Shuting; Yang, Peng; Qian, Kang et al. · 2022 · Bioactive materials · DOI

Full title: Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease.

Authors: Xu, Shuting; Yang, Peng; Qian, Kang; Li, Yixian; Guo, Qian; Wang, Pengzhen; Meng, Ran; Wu, Jing; Cao, Jinxu; Cheng, Yunlong; Xu, Minjun; Zhang, Qizhi

Year: 2022

Venue: Bioactive materials

DOI: https://doi.org/10.1016/j.bioactmat.2021.09.017

Paper Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P62.

Fairley, Lauren H; Grimm, Amandine; Herff, Steffen A et al. · 2024 · Biochimie · DOI

Full title: Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P62.

Authors: Fairley, Lauren H; Grimm, Amandine; Herff, Steffen A; Eckert, Anne

Year: 2024

Venue: Biochimie

DOI: https://doi.org/10.1016/j.biochi.2024.01.012

Paper Targeting autophagy via mitochondrial uncoupling: Discovery of novel serratin derivative as a potential therapeutic for Parkinson's disease.

Rudenko, Alexander Yu; Guseva, Ekaterina А; Ozhiganov, Ratislav M et al. · 2026 · Biochimie · DOI

Full title: Targeting autophagy via mitochondrial uncoupling: Discovery of novel serratin derivative as a potential therapeutic for Parkinson's disease.

Authors: Rudenko, Alexander Yu; Guseva, Ekaterina А; Ozhiganov, Ratislav M; Myasnikov, Boris P; Belopolskaya, Maria V; Fadeeva, Olga V; Morgun, Elena О; Averina, Olga A; Tukhovskaya, Elena A; Slashcheva, Gulsara A; Dyachenko, Igor A; Marusich, Elena I; Mokhina, Mariia; Zaranaina, Rose-Lys; Ikhalaynen, Yuriy A; Rodin, Igor A; Khailova, Ljudmila S; Antonenko, Yuri N; Polshakov, Vladimir I; Lovat, Maxim L; Kartsev, Viktor G; Murashev, Arkady N; Sergiev, Petr V

Year: 2026

Venue: Biochimie

DOI: https://doi.org/10.1016/j.biochi.2025.10.011

Paper Berberine attenuates apoptosis in rat retinal Müller cells stimulated with high glucose via enhancing autophagy and the AMPK/mTOR signaling.

Chen, Han; Ji, Yingshi; Yan, Xin et al. · 2018 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Berberine attenuates apoptosis in rat retinal Müller cells stimulated with high glucose via enhancing autophagy and the AMPK/mTOR signaling.

Authors: Chen, Han; Ji, Yingshi; Yan, Xin; Su, Guanfang; Chen, Li; Xiao, Jun

Year: 2018

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2018.09.140

Paper Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells.

Baskaran, Rathinasamy; Poornima, Paramasivan; Priya, Lohanathan Bharathi et al. · 2016 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells.

Authors: Baskaran, Rathinasamy; Poornima, Paramasivan; Priya, Lohanathan Bharathi; Huang, Chih-Yang; Padma, Viswanadha Vijaya

Year: 2016

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2016.08.063

Paper Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy signaling.

He, Liumin; Sun, Zhongqing; Li, Jianshuang et al. · 2021 · Biomaterials · DOI

Full title: Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy signaling.

Authors: He, Liumin; Sun, Zhongqing; Li, Jianshuang; Zhu, Rong; Niu, Ben; Tam, Ka Long; Xiao, Qiao; Li, Jun; Wang, Wenjun; Tsui, Chi Ying; Hong Lee, Vincent Wing; So, Kwok-Fai; Xu, Ying; Ramakrishna, Seeram; Zhou, Qinghua; Chiu, Kin

Year: 2021

Venue: Biomaterials

DOI: https://doi.org/10.1016/j.biomaterials.2020.120585

Paper Effect and proposed mechanism of vitamin C modulating amino acid regulation of autophagic proteolysis.

Karim, Md Razaul; Kadowaki, Motoni · 2017 · Biochimie · DOI

Full title: Effect and proposed mechanism of vitamin C modulating amino acid regulation of autophagic proteolysis.

Authors: Karim, Md Razaul; Kadowaki, Motoni

Year: 2017

Venue: Biochimie

DOI: https://doi.org/10.1016/j.biochi.2017.08.004

Paper Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages.

Liu, Beibei; Deng, Xiaoling; Jiang, Qianqian et al. · 2020 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages.

Authors: Liu, Beibei; Deng, Xiaoling; Jiang, Qianqian; Li, Guixin; Zhang, Junli; Zhang, Ning; Xin, Shengliang; Xu, Keshu

Year: 2020

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2020.109895

Paper Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells.

Shi, Yao; Liu, Xiao-Yan; Jiang, Yi-Ping et al. · 2020 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells.

Authors: Shi, Yao; Liu, Xiao-Yan; Jiang, Yi-Ping; Zhang, Jia-Bao; Zhang, Qiao-Yan; Wang, Na-Ni; Xin, Hai-Liang

Year: 2020

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2019.109566

Paper d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.

Lin, Zhiming; Miao, Jianing; Zhang, Tao et al. · 2021 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.

Authors: Lin, Zhiming; Miao, Jianing; Zhang, Tao; He, Ming; Zhou, Xiaonan; Zhang, He; Gao, Yue; Bai, Lunhao

Year: 2021

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2020.111199

Paper Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.

Hu, Guofu; Yuan, Zihui; Wang, Jian · 2023 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.

Authors: Hu, Guofu; Yuan, Zihui; Wang, Jian

Year: 2023

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2023.114333

Paper Matrine protects oligodendrocytes by inhibiting their apoptosis and enhancing mitochondrial autophagy.

Wang, Meng-Ru; Zhang, Xiao-Jian; Liu, Hong-Chun et al. · 2019 · Brain research bulletin · DOI

Full title: Matrine protects oligodendrocytes by inhibiting their apoptosis and enhancing mitochondrial autophagy.

Authors: Wang, Meng-Ru; Zhang, Xiao-Jian; Liu, Hong-Chun; Ma, Wen-Di; Zhang, Ming-Liang; Zhang, Yuan; Li, Xing; Dou, Meng-Meng; Jing, Yi-Lei; Chu, Yao-Juan; Zhu, Lin

Year: 2019

Venue: Brain research bulletin

DOI: https://doi.org/10.1016/j.brainresbull.2019.08.006

Paper Excessive Protein Accumulation and Impaired Autophagy in the Hippocampus of Angelman Syndrome Modeled in Mice.

Aria, Francesca; Pandey, Kiran; Alberini, Cristina M · 2023 · Biological psychiatry · DOI

Full title: Excessive Protein Accumulation and Impaired Autophagy in the Hippocampus of Angelman Syndrome Modeled in Mice.

Authors: Aria, Francesca; Pandey, Kiran; Alberini, Cristina M

Year: 2023

Venue: Biological psychiatry

DOI: https://doi.org/10.1016/j.biopsych.2022.11.016

Paper Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons.

Zhang, Zhenyuan; Zhang, Lan; Zhang, Yidan et al. · 2025 · Brain research bulletin · DOI

Full title: Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons.

Authors: Zhang, Zhenyuan; Zhang, Lan; Zhang, Yidan; Zhao, Yuan; Gao, Ya; Zhang, Cong; Li, Dongxiao; Zhang, Xiangjian; Yang, Guofeng; Zhang, Jian

Year: 2025

Venue: Brain research bulletin

DOI: https://doi.org/10.1016/j.brainresbull.2025.111501

Paper Casticin in cancer research: in vitro evidence and mechanistic insights into its antitumor potential.

Łapa, Aleksandra; Kocot, Natalia; Piska, Kamil et al. · 2026 · Chemico-biological interactions · DOI

Full title: Casticin in cancer research: in vitro evidence and mechanistic insights into its antitumor potential.

Authors: Łapa, Aleksandra; Kocot, Natalia; Piska, Kamil; Wójcik-Pszczoła, Katarzyna; Pękala, Elżbieta; Koczurkiewicz-Adamczyk, Paulina

Year: 2026

Venue: Chemico-biological interactions

DOI: https://doi.org/10.1016/j.cbi.2025.111870

Paper Inhibition of miR-34a-5p alleviates hypoxia-reoxygenation injury by enhancing autophagy in steatotic hepatocytes.

Li, Chuanjiang; Wang, Kai; Guo, Linghong et al. · 2018 · Biology open · DOI

Full title: Inhibition of miR-34a-5p alleviates hypoxia-reoxygenation injury by enhancing autophagy in steatotic hepatocytes.

Authors: Li, Chuanjiang; Wang, Kai; Guo, Linghong; Sun, Hang; Huang, Hai; Lin, XinXin; Li, Qingping

Year: 2018

Venue: Biology open

DOI: https://doi.org/10.1242/bio.033290

Paper Translating the biology of aging into novel therapeutics for Alzheimer disease

Hara, Yuko; McKeehan, Nicholas; Fillit, Howard · 2018 · Neurology · DOI

Full title: Translating the biology of aging into novel therapeutics for Alzheimer disease

Authors: Hara, Yuko; McKeehan, Nicholas; Fillit, Howard

Year: 2018

Venue: Neurology

DOI: https://doi.org/10.1212/wnl.0000000000006745

Paper Propofol Inhibits HeLa Cells by Impairing Autophagic Flux via AMP-Activated Protein Kinase (AMPK) Activation and Endoplasmic Reticulum Stress Regulated by Calcium.

Chen, Xi; Li, Kai; Zhao, Guoqing · 2018 · Medical science monitor : international medical journal of experimental and clinical research · DOI

Full title: Propofol Inhibits HeLa Cells by Impairing Autophagic Flux via AMP-Activated Protein Kinase (AMPK) Activation and Endoplasmic Reticulum Stress Regulated by Calcium.

Authors: Chen, Xi; Li, Kai; Zhao, Guoqing

Year: 2018

Venue: Medical science monitor : international medical journal of experimental and clinical research

DOI: https://doi.org/10.12659/msm.909144

Paper Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.

Hawkins, Kate; Watt, Meg; Gillotin, Sébastien et al. · 2024 · Biology open · DOI

Full title: Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.

Authors: Hawkins, Kate; Watt, Meg; Gillotin, Sébastien; Hanspal, Maya; Helley, Martin; Richardson, Jill; Corbett, Nicola; Brownlees, Janet

Year: 2024

Venue: Biology open

DOI: https://doi.org/10.1242/bio.060380

Paper Role of Hypoxia-Inducible Factors 1α (HIF1α) in SH-SY5Y Cell Autophagy Induced by Oxygen-Glucose Deprivation.

Niu, Guohui; Zhu, Dengna; Zhang, Xiaoli et al. · 2018 · Medical science monitor : international medical journal of experimental and clinical research · DOI

Full title: Role of Hypoxia-Inducible Factors 1α (HIF1α) in SH-SY5Y Cell Autophagy Induced by Oxygen-Glucose Deprivation.

Authors: Niu, Guohui; Zhu, Dengna; Zhang, Xiaoli; Wang, Jun; Zhao, Yunxia; Wang, Xin

Year: 2018

Venue: Medical science monitor : international medical journal of experimental and clinical research

DOI: https://doi.org/10.12659/MSM.905140

Paper An AMPK-dependent regulatory pathway in tau-mediated toxicity.

Galasso, Alessia; Cameron, Charles S; Frenguelli, Bruno G et al. · 2017 · Biology open · DOI

Full title: An AMPK-dependent regulatory pathway in tau-mediated toxicity.

Authors: Galasso, Alessia; Cameron, Charles S; Frenguelli, Bruno G; Moffat, Kevin G

Year: 2017

Venue: Biology open

DOI: https://doi.org/10.1242/bio.022863

Paper Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy.

Ma, Yayu; Gai, Ya; Yan, Jingpeng et al. · 2016 · Medical science monitor : international medical journal of experimental and clinical research · DOI

Full title: Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy.

Authors: Ma, Yayu; Gai, Ya; Yan, Jingpeng; Li, Jian; Zhang, Yangyang

Year: 2016

Venue: Medical science monitor : international medical journal of experimental and clinical research

DOI: https://doi.org/10.12659/msm.897379

Paper Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila.

Onkar, Akanksha; Sheshadri, Deepashree; Rai, Anupama et al. · 2023 · Disease models & mechanisms · DOI

Full title: Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila.

Authors: Onkar, Akanksha; Sheshadri, Deepashree; Rai, Anupama; Gupta, Arjit Kant; Gupta, Nitin; Ganesh, Subramaniam

Year: 2023

Venue: Disease models & mechanisms

DOI: https://doi.org/10.1242/dmm.050238

Paper Metformin Enhances Functional Recovery of Peripheral Nerve in Rats with Sciatic Nerve Crush Injury.

Liu, Lei; Tian, Dehu; Liu, Chunjie et al. · 2019 · Medical science monitor : international medical journal of experimental and clinical research · DOI

Full title: Metformin Enhances Functional Recovery of Peripheral Nerve in Rats with Sciatic Nerve Crush Injury.

Authors: Liu, Lei; Tian, Dehu; Liu, Chunjie; Yu, Kunlun; Bai, Jiangbo

Year: 2019

Venue: Medical science monitor : international medical journal of experimental and clinical research

DOI: https://doi.org/10.12659/MSM.918277

Paper Potentials of autophagy enhancing natural products in the treatment of Parkinson disease.

Olubodun-Obadun, Taiwo G; Ishola, Ismail O; Adeyemi, Olufunmilayo O · 2021 · Drug metabolism and personalized therapy · DOI

Full title: Potentials of autophagy enhancing natural products in the treatment of Parkinson disease.

Authors: Olubodun-Obadun, Taiwo G; Ishola, Ismail O; Adeyemi, Olufunmilayo O

Year: 2021

Venue: Drug metabolism and personalized therapy

DOI: https://doi.org/10.1515/dmpt-2021-0128

Paper The role of oxidative stress during inflammatory processes

Lugrin, Jérôme; Rosenblatt‐Velin, Nathalie; Parapanov, Roumen et al. · 2013 · Biological Chemistry · DOI

Full title: The role of oxidative stress during inflammatory processes

Authors: Lugrin, Jérôme; Rosenblatt‐Velin, Nathalie; Parapanov, Roumen; Liaudet, Lucas

Year: 2013

Venue: Biological Chemistry

DOI: https://doi.org/10.1515/hsz-2013-0241

Paper Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy.

Xu, Zhenru; Han, Xu; Ou, Daming et al. · 2020 · Applied microbiology and biotechnology · DOI

Full title: Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy.

Authors: Xu, Zhenru; Han, Xu; Ou, Daming; Liu, Ting; Li, Zunxiong; Jiang, Guanmin; Liu, Jing; Zhang, Ji

Year: 2020

Venue: Applied microbiology and biotechnology

DOI: https://doi.org/10.1007/s00253-019-10257-8

Paper Parthenolide ameliorates bilirubin-induced neuronal cell injury by mediating autophagy.

Liu, Junling; Zhang, Chunli; Hu, Yuanyuan et al. · 2026 · Experimental brain research · DOI

Full title: Parthenolide ameliorates bilirubin-induced neuronal cell injury by mediating autophagy.

Authors: Liu, Junling; Zhang, Chunli; Hu, Yuanyuan; Zheng, Zong

Year: 2026

Venue: Experimental brain research

DOI: https://doi.org/10.1007/s00221-026-07235-8

Paper Enhancing Fat Graft Survival via Upregulating Autophagy of Adipocytes.

Jia, Xinyu; Chai, Yimeng; Zhu, Jinglin et al. · 2024 · Aesthetic plastic surgery · DOI

Full title: Enhancing Fat Graft Survival via Upregulating Autophagy of Adipocytes.

Authors: Jia, Xinyu; Chai, Yimeng; Zhu, Jinglin; Zhang, Xinyu; Jiang, Chanyuan; Yin, Ningbei; Li, Facheng

Year: 2024

Venue: Aesthetic plastic surgery

DOI: https://doi.org/10.1007/s00266-023-03797-y

Paper Circ-FoxO3 alleviates APOE4-induced brain pathology through FoxO3-mediated autophagy.

He, Kejing; Wei, Houlin; Chen, Qi et al. · 2026 · Molecular genetics and genomics : MGG · DOI

Full title: Circ-FoxO3 alleviates APOE4-induced brain pathology through FoxO3-mediated autophagy.

Authors: He, Kejing; Wei, Houlin; Chen, Qi; Wen, Xueyi; Ding, Weilong; Li, Yufeng; Li, Keshen; Yang, Zhenguo

Year: 2026

Venue: Molecular genetics and genomics : MGG

DOI: https://doi.org/10.1007/s00438-026-02348-9

Paper The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations.

Giorgi, Filippo Sean; Biagioni, Francesca; Lenzi, Paola et al. · 2015 · Journal of neural transmission (Vienna, Austria : 1996) · DOI

Full title: The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations.

Authors: Giorgi, Filippo Sean; Biagioni, Francesca; Lenzi, Paola; Frati, Alessandro; Fornai, Francesco

Year: 2015

Venue: Journal of neural transmission (Vienna, Austria : 1996)

DOI: https://doi.org/10.1007/s00702-014-1312-1

Paper Deconvoluting the relationships between autophagy and metastasis for potential cancer therapy.

Yao, Dahong; Wang, Peiqi; Zhang, Jin et al. · 2016 · Apoptosis : an international journal on programmed cell death · DOI

Full title: Deconvoluting the relationships between autophagy and metastasis for potential cancer therapy.

Authors: Yao, Dahong; Wang, Peiqi; Zhang, Jin; Fu, Leilei; Ouyang, Liang; Wang, Jinhui

Year: 2016

Venue: Apoptosis : an international journal on programmed cell death

DOI: https://doi.org/10.1007/s10495-016-1237-2

Paper Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis.

Wang, Zhen-Yu; Lin, Jian-Hua; Muharram, Akram et al. · 2014 · Apoptosis : an international journal on programmed cell death · DOI

Full title: Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis.

Authors: Wang, Zhen-Yu; Lin, Jian-Hua; Muharram, Akram; Liu, Wen-Ge

Year: 2014

Venue: Apoptosis : an international journal on programmed cell death

DOI: https://doi.org/10.1007/s10495-014-0976-1

Paper Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Khan, Sher Hayat; Zhao, Deming; Shah, Syed Zahid Ali et al. · 2017 · Cellular and molecular neurobiology · DOI

Full title: Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Authors: Khan, Sher Hayat; Zhao, Deming; Shah, Syed Zahid Ali; Hassan, Mohammad Farooque; Zhu, Ting; Song, Zhiqi; Zhou, Xiangmei; Yang, Lifeng

Year: 2017

Venue: Cellular and molecular neurobiology

DOI: https://doi.org/10.1007/s10571-016-0407-7

Paper CD47 signaling in aging and age-related diseases: mechanisms, challenges, and therapeutic opportunities.

Mutombo Menga, Arsene; Hong, Xin; Zhu, Lei · 2025 · Biogerontology · DOI

Full title: CD47 signaling in aging and age-related diseases: mechanisms, challenges, and therapeutic opportunities.

Authors: Mutombo Menga, Arsene; Hong, Xin; Zhu, Lei

Year: 2025

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-025-10370-4

Paper S-palmitoylation in ferroptosis: molecular mechanisms, modulators, and interplay with autophagy.

Wang, Leilei; Wang, Chuan; He, Hong · 2026 · Apoptosis : an international journal on programmed cell death · DOI

Full title: S-palmitoylation in ferroptosis: molecular mechanisms, modulators, and interplay with autophagy.

Authors: Wang, Leilei; Wang, Chuan; He, Hong

Year: 2026

Venue: Apoptosis : an international journal on programmed cell death

DOI: https://doi.org/10.1007/s10495-025-02227-5

Paper Harnessing the FOXO-SIRT1 axis: insights into cellular stress, metabolism, and aging.

Gupta, Saurabh; Afzal, Muhammad; Agrawal, Neetu et al. · 2025 · Biogerontology · DOI

Full title: Harnessing the FOXO-SIRT1 axis: insights into cellular stress, metabolism, and aging.

Authors: Gupta, Saurabh; Afzal, Muhammad; Agrawal, Neetu; Almalki, Waleed Hassan; Rana, Mohit; Gangola, Saurabh; Chinni, Suresh V; Kumar K, Benod; Ali, Haider; Singh, Sachin Kumar; Jha, Saurabh Kumar; Gupta, Gaurav

Year: 2025

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-025-10207-0

Paper BRI3 Orchestrates Lipid Metabolism and Autophagy in Glioblastoma: Implications for Tumor Cell Resilience.

Chen, Jun; Zuo, Pin; Kuang, Situo et al. · 2025 · Biochemical genetics · DOI

Full title: BRI3 Orchestrates Lipid Metabolism and Autophagy in Glioblastoma: Implications for Tumor Cell Resilience.

Authors: Chen, Jun; Zuo, Pin; Kuang, Situo; Li, Ping; Li, Xiaoquan; Zhan, Dong

Year: 2025

Venue: Biochemical genetics

DOI: https://doi.org/10.1007/s10528-025-11225-w

Paper Aging and age‐related diseases: from mechanisms to therapeutic strategies

Li, Zhe; Zhang, Zhenkun; Ren, Yikun et al. · 2021 · Biogerontology · DOI

Full title: Aging and age‐related diseases: from mechanisms to therapeutic strategies

Authors: Li, Zhe; Zhang, Zhenkun; Ren, Yikun; Wang, Yingying; Fang, Jiarui; Yue, Han; Ma, Shanshan; Guan, Fangxia

Year: 2021

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-021-09910-5

Paper Rapamycin Protects Sepsis-Induced Cognitive Impairment in Mouse Hippocampus by Enhancing Autophagy.

Liu, Wenyu; Guo, Jia'nan; Mu, Jie et al. · 2017 · Cellular and molecular neurobiology · DOI

Full title: Rapamycin Protects Sepsis-Induced Cognitive Impairment in Mouse Hippocampus by Enhancing Autophagy.

Authors: Liu, Wenyu; Guo, Jia'nan; Mu, Jie; Tian, Linyu; Zhou, Dong

Year: 2017

Venue: Cellular and molecular neurobiology

DOI: https://doi.org/10.1007/s10571-016-0449-x

Paper Pparα activation stimulates autophagic flux through lipid catabolism-independent route.

Zhang, Yan-Yu; Wang, Jun-Xian; Qiao, Fang et al. · 2024 · Fish physiology and biochemistry · DOI

Full title: Pparα activation stimulates autophagic flux through lipid catabolism-independent route.

Authors: Zhang, Yan-Yu; Wang, Jun-Xian; Qiao, Fang; Zhang, Mei-Ling; Luo, Yuan; Du, Zhen-Yu

Year: 2024

Venue: Fish physiology and biochemistry

DOI: https://doi.org/10.1007/s10695-024-01327-4

Paper Autophagy Suppresses Ferroptosis by Degrading TFR1 to Alleviate Cognitive Dysfunction in Mice with SAE.

Du, Lixia; Wu, You; Jia, Qi et al. · 2023 · Cellular and molecular neurobiology · DOI

Full title: Autophagy Suppresses Ferroptosis by Degrading TFR1 to Alleviate Cognitive Dysfunction in Mice with SAE.

Authors: Du, Lixia; Wu, You; Jia, Qi; Li, Jin; Li, Yi; Ma, Hongwei; Fan, Zhongmin; Guo, Xiaofeng; Li, Ling; Peng, Yuliang; Li, Jing; Fang, Zongping; Zhang, Xijing

Year: 2023

Venue: Cellular and molecular neurobiology

DOI: https://doi.org/10.1007/s10571-023-01370-4

Paper Hesperetin ameliorates mitochondrial dysfunction in acute kidney injury by mediating autophagy and inhibiting the cGAS-STING pathway.

Cao, Pei; Zhu, Wan; Li, Deng et al. · 2025 · Journal of molecular histology · DOI

Full title: Hesperetin ameliorates mitochondrial dysfunction in acute kidney injury by mediating autophagy and inhibiting the cGAS-STING pathway.

Authors: Cao, Pei; Zhu, Wan; Li, Deng; Zhang, JiGang; Feng, Xing

Year: 2025

Venue: Journal of molecular histology

DOI: https://doi.org/10.1007/s10735-025-10602-4

Paper Genistein protects against ox-LDL-induced senescence through enhancing SIRT1/LKB1/AMPK-mediated autophagy flux in HUVECs.

Zhang, Huaping; Yang, Xiaorong; Pang, Xuefen et al. · 2019 · Molecular and cellular biochemistry · DOI

Full title: Genistein protects against ox-LDL-induced senescence through enhancing SIRT1/LKB1/AMPK-mediated autophagy flux in HUVECs.

Authors: Zhang, Huaping; Yang, Xiaorong; Pang, Xuefen; Zhao, Zhenxiang; Yu, Haixia; Zhou, Hui

Year: 2019

Venue: Molecular and cellular biochemistry

DOI: https://doi.org/10.1007/s11010-018-3476-8

Paper Down-regulation of miRNA-30a alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy.

Wang, Peng; Liang, Jia; Li, Yun et al. · 2014 · Neurochemical research · DOI

Full title: Down-regulation of miRNA-30a alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy.

Authors: Wang, Peng; Liang, Jia; Li, Yun; Li, Jiefei; Yang, Xuan; Zhang, Xinxin; Han, Song; Li, Shujuan; Li, Junfa

Year: 2014

Venue: Neurochemical research

DOI: https://doi.org/10.1007/s11064-014-1310-6

Paper Curcumin promotes functional recovery after spinal cord injury by enhancing autophagic flux and attenuating apoptosis.

Ismaeel, Ghufran Lutfi; Zaidan, Haider Kamil; Alshaikh Faqri, Ayoob Murtadha et al. · 2025 · Molecular biology reports · DOI

Full title: Curcumin promotes functional recovery after spinal cord injury by enhancing autophagic flux and attenuating apoptosis.

Authors: Ismaeel, Ghufran Lutfi; Zaidan, Haider Kamil; Alshaikh Faqri, Ayoob Murtadha; Al-Musawi, Tariq J; Mudhafar, Mustafa; Alsailawi, Hasan Ali

Year: 2025

Venue: Molecular biology reports

DOI: https://doi.org/10.1007/s11033-025-10869-6

Paper Tert-butylhydroquinone Ameliorates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Mice by Enhancing Nrf2-Independent Autophagy.

Li, Tao; Sun, Kang-jian; Wang, Han-Dong et al. · 2015 · Neurochemical research · DOI

Full title: Tert-butylhydroquinone Ameliorates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Mice by Enhancing Nrf2-Independent Autophagy.

Authors: Li, Tao; Sun, Kang-jian; Wang, Han-Dong; Zhou, Meng-Liang; Ding, Ke; Lu, Xin-Yu; Wei, Wu-Ting; Wang, Chun-Xi; Zhou, Xiao-Ming

Year: 2015

Venue: Neurochemical research

DOI: https://doi.org/10.1007/s11064-015-1672-4

Paper Enhanced Autophagy Contributes to Protective Effects of GM1 Ganglioside Against Aβ1-42-Induced Neurotoxicity and Cognitive Deficits.

Dai, Ruwei; Zhang, Shijie; Duan, Wenjun et al. · 2017 · Neurochemical research · DOI

Full title: Enhanced Autophagy Contributes to Protective Effects of GM1 Ganglioside Against Aβ1-42-Induced Neurotoxicity and Cognitive Deficits.

Authors: Dai, Ruwei; Zhang, Shijie; Duan, Wenjun; Wei, Renrong; Chen, Huifang; Cai, Weibin; Yang, Lei; Wang, Qi

Year: 2017

Venue: Neurochemical research

DOI: https://doi.org/10.1007/s11064-017-2266-0

Paper Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.

Tian, Jun; Yang, Lei; Wang, Pengfei et al. · 2020 · Neurochemical research · DOI

Full title: Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.

Authors: Tian, Jun; Yang, Lei; Wang, Pengfei; Yang, Lijun; Fan, Zhenzeng

Year: 2020

Venue: Neurochemical research

DOI: https://doi.org/10.1007/s11064-020-03141-9

Paper Melatonin Enhances Autophagy and Reduces Apoptosis to Promote Locomotor Recovery in Spinal Cord Injury via the PI3K/AKT/mTOR Signaling Pathway.

Li, Yuanlong; Guo, Yue; Fan, Yue et al. · 2019 · Neurochemical research · DOI

Full title: Melatonin Enhances Autophagy and Reduces Apoptosis to Promote Locomotor Recovery in Spinal Cord Injury via the PI3K/AKT/mTOR Signaling Pathway.

Authors: Li, Yuanlong; Guo, Yue; Fan, Yue; Tian, He; Li, Kuo; Mei, Xifan

Year: 2019

Venue: Neurochemical research

DOI: https://doi.org/10.1007/s11064-019-02838-w

Paper Role of AMPK in atherosclerosis via autophagy regulation.

Ou, Hanxiao; Liu, Chuhao; Feng, Wenjie et al. · 2018 · Science China. Life sciences · DOI

Full title: Role of AMPK in atherosclerosis via autophagy regulation.

Authors: Ou, Hanxiao; Liu, Chuhao; Feng, Wenjie; Xiao, Xinwen; Tang, Shengsong; Mo, Zhongcheng

Year: 2018

Venue: Science China. Life sciences

DOI: https://doi.org/10.1007/s11427-017-9240-2

Paper MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9.

Yang, Jurong; Chen, Dapeng; He, Yani et al. · 2013 · Age (Dordrecht, Netherlands) · DOI

Full title: MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9.

Authors: Yang, Jurong; Chen, Dapeng; He, Yani; Meléndez, Alicia; Feng, Zhe; Hong, Quan; Bai, Xueyuan; Li, Qinggang; Cai, Guangyan; Wang, Jianzhong; Chen, Xiangmei

Year: 2013

Venue: Age (Dordrecht, Netherlands)

DOI: https://doi.org/10.1007/s11357-011-9324-3

Paper Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing Autophagy by Up-regulating Beclin-1.

Li, Xigong; Lou, Xianfeng; Xu, Sanzhong et al. · 2018 · Journal of molecular neuroscience : MN · DOI

Full title: Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing Autophagy by Up-regulating Beclin-1.

Authors: Li, Xigong; Lou, Xianfeng; Xu, Sanzhong; Wang, Quan; Shen, Miaoda; Miao, Jing

Year: 2018

Venue: Journal of molecular neuroscience : MN

DOI: https://doi.org/10.1007/s12031-018-1179-y

Paper Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance.

Yung, Cheryl; Sha, Di; Li, Lian et al. · 2016 · Molecular neurobiology · DOI

Full title: Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance.

Authors: Yung, Cheryl; Sha, Di; Li, Lian; Chin, Lih-Shen

Year: 2016

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-015-9537-z

Paper The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy.

Jang, Wooyoung; Kim, Hee Ju; Li, Huan et al. · 2016 · Molecular neurobiology · DOI

Full title: The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy.

Authors: Jang, Wooyoung; Kim, Hee Ju; Li, Huan; Jo, Kwang Deog; Lee, Moon Kyu; Yang, Hyun Ok

Year: 2016

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-015-9316-x

Paper Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities.

Morais, Gustavo Paroschi; de Sousa Neto, Ivo Vieira; Veras, Allice Santos Cruz et al. · 2025 · Molecular neurobiology · DOI

Full title: Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities.

Authors: Morais, Gustavo Paroschi; de Sousa Neto, Ivo Vieira; Veras, Allice Santos Cruz; Teixeira, Giovana Rampazzo; Paroschi, Luciana Oliveira; Pinto, Ana Paula; Dos Santos, Jonathas Rodrigo; Alberici, Luciane Carla; Cintra, Dennys Esper Corrêa; Pauli, José Rodrigo; Morelli, Ana Paula; Ropelle, Eduardo Rochete; da Silva, Adelino Sanchez Ramos

Year: 2025

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-025-05066-2

Paper Berberine can be a Potential Therapeutic Agent in Treatment of Huntington's Disease: A Proposed Mechanistic Insight.

Sharma, Seema; Kaur, Inderpreet; Dubey, Naina et al. · 2025 · Molecular neurobiology · DOI

Full title: Berberine can be a Potential Therapeutic Agent in Treatment of Huntington's Disease: A Proposed Mechanistic Insight.

Authors: Sharma, Seema; Kaur, Inderpreet; Dubey, Naina; Goswami, Neelima; Tanwar, Sampat Singh

Year: 2025

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-025-05054-6

Paper Tempol Mitigates Cisplatin-Induced Retinopathy by Modulating ER Stress, Enhancing Autophagy, and Preserving Neurotrophic Support.

Eldemerdash, Reham Talaat; Alsemeh, Amira Ebrahim; Mokhtar, Hanan E L et al. · 2025 · Molecular neurobiology · DOI

Full title: Tempol Mitigates Cisplatin-Induced Retinopathy by Modulating ER Stress, Enhancing Autophagy, and Preserving Neurotrophic Support.

Authors: Eldemerdash, Reham Talaat; Alsemeh, Amira Ebrahim; Mokhtar, Hanan E L; Desouky, Maha K; Elhassan, Yasir Hassan; Samak, Mai A; Hulail, Mohey A E

Year: 2025

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-025-05605-x

Paper Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response

Mohanty, Abhishek; Tiwari-Pandey, Rashmi; Pandey, Nihar R. · 2019 · Journal of Cell Communication and Signaling · DOI

Full title: Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response

Authors: Mohanty, Abhishek; Tiwari-Pandey, Rashmi; Pandey, Nihar R.

Year: 2019

Venue: Journal of Cell Communication and Signaling

DOI: https://doi.org/10.1007/s12079-019-00507-9

Paper Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

Xu, Xiaoyan; Sun, Yaqin; Cen, Xufeng et al. · 2021 · Protein & Cell · DOI

Full title: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

Authors: Xu, Xiaoyan; Sun, Yaqin; Cen, Xufeng; Shan, Bing; Zhao, Qingwei; Xie, Tingxue; Wang, Zhe; Hou, Tingjun; Xue, Yu; Zhang, Mengmeng; Peng, Di; Sun, Qiming; Yi, Cong; Najafov, Ayaz; Xia, Hongguang

Year: 2021

Venue: Protein & Cell

DOI: https://doi.org/10.1007/s13238-021-00858-3

Paper Triptonide Mediates Apoptosis and Autophagy via ROS/p38 MAPK Activation and mTOR/NF-κB Inhibition in Nasopharyngeal Carcinoma: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation.

Geng, Shikai; Liu, Xingyu; Wan, Fangzhu et al. · 2025 · Current pharmaceutical design · DOI

Full title: Triptonide Mediates Apoptosis and Autophagy via ROS/p38 MAPK Activation and mTOR/NF-κB Inhibition in Nasopharyngeal Carcinoma: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation.

Authors: Geng, Shikai; Liu, Xingyu; Wan, Fangzhu; Chen, Li; Lin, Wanzun; Hu, Wei; Le, Ziyu; Chen, Huaiyuan; Huang, Qingting; Su, Fengtao; Shao, Chunlin; Lu, Jiade J; Kong, Lin

Year: 2025

Venue: Current pharmaceutical design

DOI: https://doi.org/10.2174/0113816128392691251008235211

Paper UFMylation: A Potential Modification for Neurological Diseases.

Che, Guanglu; Xiao, Xiao; Li, Tingyu et al. · 2025 · Current neuropharmacology · DOI

Full title: UFMylation: A Potential Modification for Neurological Diseases.

Authors: Che, Guanglu; Xiao, Xiao; Li, Tingyu; Li, Jingdong; Gao, Linbo

Year: 2025

Venue: Current neuropharmacology

DOI: https://doi.org/10.2174/011570159X340639240905092813

Paper Inhibition of the P2Y2 Receptor Promotes Facial Nerve Function by Enhancing Neuron Autophagy.

Song, Xianmin; Gao, Yingna; Zhu, Minhui et al. · 2025 · Current neuropharmacology · DOI

Full title: Inhibition of the P2Y2 Receptor Promotes Facial Nerve Function by Enhancing Neuron Autophagy.

Authors: Song, Xianmin; Gao, Yingna; Zhu, Minhui; Zheng, Hongliang; Wang, Wei; Chen, Shicai

Year: 2025

Venue: Current neuropharmacology

DOI: https://doi.org/10.2174/011570159X349328250717113503

Paper Conformational diseases and ER stress-mediated cell death: apoptotic cell death and autophagic cell death.

Momoi, Takashi · 2006 · Current molecular medicine · DOI

Full title: Conformational diseases and ER stress-mediated cell death: apoptotic cell death and autophagic cell death.

Authors: Momoi, Takashi

Year: 2006

Venue: Current molecular medicine

DOI: https://doi.org/10.2174/156652406775574596

Paper Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

Altomare, Deborah A.; Khaled, Annette R. · 2012 · Current Medicinal Chemistry · DOI

Full title: Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

Authors: Altomare, Deborah A.; Khaled, Annette R.

Year: 2012

Venue: Current Medicinal Chemistry

DOI: https://doi.org/10.2174/092986712801661130

Paper Dermal Fibroblasts-derived Exosomes Alleviated Bronchopulmonary Dysplasia in Neonatal Rats Partially by Regulating Autophagy.

Wang, Shi; Chen, Cuie; Zhang, Xixi et al. · 2025 · Current stem cell research & therapy · DOI

Full title: Dermal Fibroblasts-derived Exosomes Alleviated Bronchopulmonary Dysplasia in Neonatal Rats Partially by Regulating Autophagy.

Authors: Wang, Shi; Chen, Cuie; Zhang, Xixi; Liu, Yuanyuan; Sheng, Anqun; Sun, Yuanyuan

Year: 2025

Venue: Current stem cell research & therapy

DOI: https://doi.org/10.2174/011574888X382647250728115724

Paper Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease

Agís-Torres, Ángel; Söllhuber, Mónica; Fernández, María Victoria et al. · 2014 · Current Neuropharmacology · DOI

Full title: Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease

Authors: Agís-Torres, Ángel; Söllhuber, Mónica; Fernández, María Victoria; Sánchez-Montero, J.M.

Year: 2014

Venue: Current Neuropharmacology

DOI: https://doi.org/10.2174/1570159x113116660047

Paper Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications

Chin, Lih‐Shen; Olzmann, James A.; Li, Lian · 2008 · Current Medicinal Chemistry · DOI

Full title: Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications

Authors: Chin, Lih‐Shen; Olzmann, James A.; Li, Lian

Year: 2008

Venue: Current Medicinal Chemistry

DOI: https://doi.org/10.2174/092986708783330692

Paper Neuroprotective Strategies for Neurological Disorders by Natural Products: An update

Rehman, Muneeb U.; Wali, Adil Farooq; Ahmad, Anas et al. · 2018 · Current Neuropharmacology · DOI

Full title: Neuroprotective Strategies for Neurological Disorders by Natural Products: An update

Authors: Rehman, Muneeb U.; Wali, Adil Farooq; Ahmad, Anas; Shakeel, Sheeba; Rasool, Saiema; Ali, Rayeesa; Rashid, Shahzada Mudasir; Madkhali, Hassan; Ganaie, Majid Ahmad; Khan, Rehan

Year: 2018

Venue: Current Neuropharmacology

DOI: https://doi.org/10.2174/1570159x16666180911124605

Paper Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation.

Xue, Yan; Wan, Baolan; Wang, Zhen et al. · 2025 · Current neuropharmacology · DOI

Full title: Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation.

Authors: Xue, Yan; Wan, Baolan; Wang, Zhen; Wang, Zhiwei; Wang, Dongzhi; Yang, Wanping; Wang, Xueting; Zhu, Li

Year: 2025

Venue: Current neuropharmacology

DOI: https://doi.org/10.2174/011570159X371235250417051313

Paper Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options

Şekerdağ, Emine; Solaroğlu, İhsan; Özdemir, Yasemin · 2018 · Current Neuropharmacology · DOI

Full title: Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options

Authors: Şekerdağ, Emine; Solaroğlu, İhsan; Özdemir, Yasemin

Year: 2018

Venue: Current Neuropharmacology

DOI: https://doi.org/10.2174/1570159x16666180302115544

Paper Role of Autophagy and Mitophagy in Neurodegenerative Disorders.

Kapil, Lakshay; Kumar, Vishal; Kaur, Simranjit et al. · 2024 · CNS & neurological disorders drug targets · DOI

Full title: Role of Autophagy and Mitophagy in Neurodegenerative Disorders.

Authors: Kapil, Lakshay; Kumar, Vishal; Kaur, Simranjit; Sharma, Deepali; Singh, Charan; Singh, Arti

Year: 2024

Venue: CNS & neurological disorders drug targets

DOI: https://doi.org/10.2174/1871527322666230327092855

Paper Therapeutic Applications of Natural Flavonoids Against Alzheimer's Disease-like Pathology: Special Focus on PI3K/Akt and Nrf2 Signaling Pathways.

Singh, Niraj Kumar; Varshney, Nikita · 2025 · Current neurovascular research · DOI

Full title: Therapeutic Applications of Natural Flavonoids Against Alzheimer's Disease-like Pathology: Special Focus on PI3K/Akt and Nrf2 Signaling Pathways.

Authors: Singh, Niraj Kumar; Varshney, Nikita

Year: 2025

Venue: Current neurovascular research

DOI: https://doi.org/10.2174/0115672026423088251205120807

Paper Androgen receptor inhibition alleviated inflammation in experimental autoimmune myocarditis by increasing autophagy in macrophages.

Ma, W-H; Zhang, X-G; Guo, L-L et al. · 2021 · European review for medical and pharmacological sciences · DOI

Full title: Androgen receptor inhibition alleviated inflammation in experimental autoimmune myocarditis by increasing autophagy in macrophages.

Authors: Ma, W-H; Zhang, X-G; Guo, L-L; Zhang, J-B; Wei, F-T; Lu, Q-H; Du, H; Kong, Y-R; Wang, X; Xu, D-L

Year: 2021

Venue: European review for medical and pharmacological sciences

DOI: https://doi.org/10.26355/eurrev_202105_25944

Paper Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation.

Yan, Huimin; Zhou, Hui-Fang; Hu, Ying et al. · 2015 · Journal of rheumatic diseases and treatment · DOI

Full title: Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation.

Authors: Yan, Huimin; Zhou, Hui-Fang; Hu, Ying; Pham, Christine T N

Year: 2015

Venue: Journal of rheumatic diseases and treatment

DOI: https://doi.org/10.23937/2469-5726/1510005

Paper Rifampicin Suppresses Amyloid-β Accumulation Through Enhancing Autophagy in the Hippocampus of a Lipopolysaccharide-Induced Mouse Model of Cognitive Decline.

Zhu, Lihong; Yuan, Qiongru; Zeng, Zhaohao et al. · 2021 · Journal of Alzheimer's disease : JAD · DOI

Full title: Rifampicin Suppresses Amyloid-β Accumulation Through Enhancing Autophagy in the Hippocampus of a Lipopolysaccharide-Induced Mouse Model of Cognitive Decline.

Authors: Zhu, Lihong; Yuan, Qiongru; Zeng, Zhaohao; Zhou, Ruiyi; Luo, Rixin; Zhang, Jiawei; Tsang, Chi Kwan; Bi, Wei

Year: 2021

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.3233/JAD-200690

Paper Herpes simplex virus type I induces an incomplete autophagic response in human neuroblastoma cells.

Santana, Soraya; Bullido, Maria Jesús; Recuero, Maria et al. · 2012 · Journal of Alzheimer's disease : JAD · DOI

Full title: Herpes simplex virus type I induces an incomplete autophagic response in human neuroblastoma cells.

Authors: Santana, Soraya; Bullido, Maria Jesús; Recuero, Maria; Valdivieso, Fernando; Aldudo, Jesus

Year: 2012

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.3233/JAD-2012-112000

Paper TGM6 variants in Parkinson's disease: clinical findings and functional evidence.

Chen, Kui; Lu, You; Peng, Fang et al. · 2020 · Journal of integrative neuroscience · DOI

Full title: TGM6 variants in Parkinson's disease: clinical findings and functional evidence.

Authors: Chen, Kui; Lu, You; Peng, Fang; Yu, Hui-Ling; Wu, Jia-Yan; Tan, Yan; Zhao, Yan-Xin

Year: 2020

Venue: Journal of integrative neuroscience

DOI: https://doi.org/10.31083/j.jin.2020.01.1203

Paper Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

Tönnies, Eric; Trushina, Eugenia · 2017 · Journal of Alzheimer s Disease · DOI

Full title: Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

Authors: Tönnies, Eric; Trushina, Eugenia

Year: 2017

Venue: Journal of Alzheimer s Disease

DOI: https://doi.org/10.3233/jad-161088

Paper Molecular Mechanisms of Amyloid Oligomers Toxicity

Kayed, Rakez; Lasagna‐Reeves, Cristian A. · 2012 · Journal of Alzheimer s Disease · DOI

Full title: Molecular Mechanisms of Amyloid Oligomers Toxicity

Authors: Kayed, Rakez; Lasagna‐Reeves, Cristian A.

Year: 2012

Venue: Journal of Alzheimer s Disease

DOI: https://doi.org/10.3233/jad-2012-129001

Paper The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

Cline, Erika N.; Bicca, Maíra A.; Viola, Kirsten L. et al. · 2018 · Journal of Alzheimer s Disease · DOI

Full title: The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

Authors: Cline, Erika N.; Bicca, Maíra A.; Viola, Kirsten L.; Klein, William L.

Year: 2018

Venue: Journal of Alzheimer s Disease

DOI: https://doi.org/10.3233/jad-179941

Paper The Role of Oxidative Stress in Parkinson's Disease

Dias, Vera; Junn, Eunsung; Mouradian, M. Maral · 2013 · Journal of Parkinson s Disease · DOI

Full title: The Role of Oxidative Stress in Parkinson's Disease

Authors: Dias, Vera; Junn, Eunsung; Mouradian, M. Maral

Year: 2013

Venue: Journal of Parkinson s Disease

DOI: https://doi.org/10.3233/jpd-130230

Paper Propionate alleviates palmitic acid-induced endoplasmic reticulum stress by enhancing autophagy in calf hepatic cells.

Gao, Wenwen; Fang, Zhiyuan; Lei, Lin et al. · 2021 · Journal of dairy science · DOI

Full title: Propionate alleviates palmitic acid-induced endoplasmic reticulum stress by enhancing autophagy in calf hepatic cells.

Authors: Gao, Wenwen; Fang, Zhiyuan; Lei, Lin; Ju, Lingxue; Jin, Bo; Loor, Juan J; Liang, Yusheng; Shi, Zhen; Shen, Taiyu; Yu, Hao; Chen, Meng; Ouyang, Hongsheng; Song, Yuxiang; Wang, Zhe; Liu, Guowen; Li, Xinwei; Du, Xiliang

Year: 2021

Venue: Journal of dairy science

DOI: https://doi.org/10.3168/jds.2020-19969

Paper Effectiveness of Nicotinamide Phosphoribosyltransferase/Pre-B Cell Colony-enhancing Factor/Visfatin in preventing High Glucose-induced Neurotoxicity in an In-vitro Model of Diabetic Neuropathy.

Jahanbani, Sarvin; Khaksari, Mehdi; Bitaraf, Fatemeh Sadat et al. · 2023 · Basic and clinical neuroscience · DOI

Full title: Effectiveness of Nicotinamide Phosphoribosyltransferase/Pre-B Cell Colony-enhancing Factor/Visfatin in preventing High Glucose-induced Neurotoxicity in an In-vitro Model of Diabetic Neuropathy.

Authors: Jahanbani, Sarvin; Khaksari, Mehdi; Bitaraf, Fatemeh Sadat; Rahmati, Majid; Foroughi, Kobra; Shayannia, Asghar

Year: 2023

Venue: Basic and clinical neuroscience

DOI: https://doi.org/10.32598/bcn.2021.2870.2

Paper PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

Truban, Dominika; Hou, Xu; Caulfield, Thomas R. et al. · 2016 · Journal of Parkinson s Disease · DOI

Full title: PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

Authors: Truban, Dominika; Hou, Xu; Caulfield, Thomas R.; Fiesel, Fabienne C.; Springer, Wolfdieter

Year: 2016

Venue: Journal of Parkinson s Disease

DOI: https://doi.org/10.3233/jpd-160989

Paper Luteolin and Exercise Combination Therapy Ameliorates Amyloid-β1-42 Oligomers-Induced Cognitive Impairment in AD Mice by Mediating Neuroinflammation and Autophagy.

Tao, Xue; Zhang, Rong; Wang, Liguo et al. · 2023 · Journal of Alzheimer's disease : JAD · DOI

Full title: Luteolin and Exercise Combination Therapy Ameliorates Amyloid-β1-42 Oligomers-Induced Cognitive Impairment in AD Mice by Mediating Neuroinflammation and Autophagy.

Authors: Tao, Xue; Zhang, Rong; Wang, Liguo; Li, Xiaoling; Gong, Weijun

Year: 2023

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.3233/JAD-220904

Paper Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

Bharadwaj, Prashant R; Verdile, Giuseppe; Barr, Renae K et al. · 2012 · Journal of Alzheimer's disease : JAD · DOI

Full title: Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

Authors: Bharadwaj, Prashant R; Verdile, Giuseppe; Barr, Renae K; Gupta, Veer; Steele, John W; Lachenmayer, M Lenard; Yue, Zhenyu; Ehrlich, Michelle E; Petsko, Gregory; Ju, Shulin; Ringe, Dagmar; Sankovich, Sonia E; Caine, Joanne M; Macreadie, Ian G; Gandy, Sam; Martins, Ralph N

Year: 2012

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.3233/JAD-2012-120178

Paper Protein Quality Control Pathways at the Crossroad of Synucleinopathies

E. P. de Mattos; A. Wentink; Carmen Nussbaum‐Krammer et al. · 2020 · Journal of Parkinson's Disease · DOI

Full title: Protein Quality Control Pathways at the Crossroad of Synucleinopathies

Authors: E. P. de Mattos; A. Wentink; Carmen Nussbaum‐Krammer; C. Hansen; Steven Bergink; R. Melki; H. Kampinga

Year: 2020

Venue: Journal of Parkinson's Disease

DOI: https://doi.org/10.3233/jpd-191790

Paper Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents

Verbaanderd, Ciska; Maes, Hannelore; Schaaf, Marco B.E. et al. · 2017 · ecancermedicalscience · DOI

Full title: Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents

Authors: Verbaanderd, Ciska; Maes, Hannelore; Schaaf, Marco B.E.; Sukhatme, Vikas P.; Pantziarka, Pan; Sukhatme, Vidula; Agostinis, Patrizia; Bouche, Gauthier

Year: 2017

Venue: ecancermedicalscience

DOI: https://doi.org/10.3332/ecancer.2017.781

Paper Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats.

Chen, Xudong; Lin, Siyang; Gu, Lei et al. · 2019 · Neurochemistry international · DOI

Full title: Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats.

Authors: Chen, Xudong; Lin, Siyang; Gu, Lei; Zhu, Xiaohong; Zhang, Yinuo; Zhang, Hongxia; Shao, Bei; Zhuge, Qichuan; Jin, Kunlin

Year: 2019

Venue: Neurochemistry international

DOI: https://doi.org/10.1016/j.neuint.2019.01.005

Paper Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy.

Yi, Li-Tao; Dong, Shu-Qi; Wang, Shuang-Shuang et al. · 2020 · Neurobiology of disease · DOI

Full title: Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy.

Authors: Yi, Li-Tao; Dong, Shu-Qi; Wang, Shuang-Shuang; Chen, Min; Li, Cheng-Fu; Geng, Di; Zhu, Ji-Xiao; Liu, Qing; Cheng, Jie

Year: 2020

Venue: Neurobiology of disease

DOI: https://doi.org/10.1016/j.nbd.2019.104715

Paper Corrigendum to "Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy" [Neurobiology of Disease 136 (2020) 104715].

Yi, Li-Tao; Dong, Shu-Qi; Wang, Shuang-Shuang et al. · 2024 · Neurobiology of disease · DOI

Full title: Corrigendum to "Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy" [Neurobiology of Disease 136 (2020) 104715].

Authors: Yi, Li-Tao; Dong, Shu-Qi; Wang, Shuang-Shuang; Chen, Min; Li, Cheng-Fu; Geng, Di; Zhu, Ji-Xiao; Liu, Qing; Cheng, Jie

Year: 2024

Venue: Neurobiology of disease

DOI: https://doi.org/10.1016/j.nbd.2024.106480

Paper RIT2 regulates autophagy lysosomal pathway induction and protects against α-synuclein pathology in a cellular model of Parkinson's disease.

Gao, Andy Y L; Montagna, Daniel R; Hirst, Warren D et al. · 2024 · Neurobiology of disease · DOI

Full title: RIT2 regulates autophagy lysosomal pathway induction and protects against α-synuclein pathology in a cellular model of Parkinson's disease.

Authors: Gao, Andy Y L; Montagna, Daniel R; Hirst, Warren D; Temkin, Paul A

Year: 2024

Venue: Neurobiology of disease

DOI: https://doi.org/10.1016/j.nbd.2024.106568

Paper Role and molecular regulatory mechanisms of Hippo signaling pathway in Caenorhabditis elegans and mammalian cell models of Alzheimer's disease.

Zhu, Man; Gu, Huan; Bai, Hua et al. · 2024 · Neurobiology of aging · DOI

Full title: Role and molecular regulatory mechanisms of Hippo signaling pathway in Caenorhabditis elegans and mammalian cell models of Alzheimer's disease.

Authors: Zhu, Man; Gu, Huan; Bai, Hua; Li, Yixin; Zhong, Chidi; Huang, Xiaowei

Year: 2024

Venue: Neurobiology of aging

DOI: https://doi.org/10.1016/j.neurobiolaging.2023.09.015

Paper Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.

Liu, Dong; Pitta, Michael; Jiang, Haiyang et al. · 2013 · Neurobiology of aging · DOI

Full title: Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.

Authors: Liu, Dong; Pitta, Michael; Jiang, Haiyang; Lee, Jong-Hwan; Zhang, Guofeng; Chen, Xinzhi; Kawamoto, Elisa M; Mattson, Mark P

Year: 2013

Venue: Neurobiology of aging

DOI: https://doi.org/10.1016/j.neurobiolaging.2012.11.020

Paper Interplay of neuropeptide Y and autophagy in Alzheimer's disease: Therapeutic perspectives and mechanistic insights.

Lanjewar, Dhiraj; Katariya, Raj; Kale, Vinita et al. · 2025 · Neuropeptides · DOI

Full title: Interplay of neuropeptide Y and autophagy in Alzheimer's disease: Therapeutic perspectives and mechanistic insights.

Authors: Lanjewar, Dhiraj; Katariya, Raj; Kale, Vinita; Taksande, Brijesh; Umekar, Milind; Vinchurney, Madhura

Year: 2025

Venue: Neuropeptides

DOI: https://doi.org/10.1016/j.npep.2025.102547

Paper Rapamycin ameliorates age-related hearing loss in C57BL/6J mice by enhancing autophagy in the SGNs.

Liu, Hongyan; Li, Feitian; Li, Xuanyi et al. · 2022 · Neuroscience letters · DOI

Full title: Rapamycin ameliorates age-related hearing loss in C57BL/6J mice by enhancing autophagy in the SGNs.

Authors: Liu, Hongyan; Li, Feitian; Li, Xuanyi; Wu, Qianru; Dai, Chunfu

Year: 2022

Venue: Neuroscience letters

DOI: https://doi.org/10.1016/j.neulet.2022.136493

Paper Enhancing autophagy in Alzheimer's disease through drug repositioning.

Eshraghi, Mehdi; Ahmadi, Mazaher; Afshar, Saeid et al. · 2022 · Pharmacology & therapeutics · DOI

Full title: Enhancing autophagy in Alzheimer's disease through drug repositioning.

Authors: Eshraghi, Mehdi; Ahmadi, Mazaher; Afshar, Saeid; Lorzadeh, Shahrokh; Adlimoghaddam, Aida; Rezvani Jalal, Nahid; West, Ryan; Dastghaib, Sanaz; Igder, Somayeh; Torshizi, Seyed Reza Naeimi; Mahmoodzadeh, Amir; Mokarram, Pooneh; Madrakian, Tayyebeh; Albensi, Benedict C; Łos, Marek J; Ghavami, Saeid; Pecic, Stevan

Year: 2022

Venue: Pharmacology & therapeutics

DOI: https://doi.org/10.1016/j.pharmthera.2022.108171

Paper Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.

Yang, Han; Wang, Yuanhe; Liu, Shan et al. · 2025 · Neurotoxicology · DOI

Full title: Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.

Authors: Yang, Han; Wang, Yuanhe; Liu, Shan; Zhang, Shan; Chen, Yuemeng; Ding, Jiuyang; Chen, Shunqin; Zhu, Faze; Xia, Bing; Luo, Peng; Liu, Yubo

Year: 2025

Venue: Neurotoxicology

DOI: https://doi.org/10.1016/j.neuro.2025.02.004

Paper Potential of plant-derived peptides for the improvement of memory and cognitive function.

Katayama, Shigeru; Corpuz, Henry M; Nakamura, Soichiro · 2021 · Peptides · DOI

Full title: Potential of plant-derived peptides for the improvement of memory and cognitive function.

Authors: Katayama, Shigeru; Corpuz, Henry M; Nakamura, Soichiro

Year: 2021

Venue: Peptides

DOI: https://doi.org/10.1016/j.peptides.2021.170571

Paper Pseudoginsenoside-F11 reduces cognitive impairment and white matter injury in vascular dementia by alleviating autophagy-lysosomal pathway deficiency.

Wang, Huiyang; Liu, Yueyang; Cui, Minghui et al. · 2024 · Phytomedicine : international journal of phytotherapy and phytopharmacology · DOI

Full title: Pseudoginsenoside-F11 reduces cognitive impairment and white matter injury in vascular dementia by alleviating autophagy-lysosomal pathway deficiency.

Authors: Wang, Huiyang; Liu, Yueyang; Cui, Minghui; Guo, Zhenkun; Zhao, Yang; Yang, Jingyu; Wu, Chunfu

Year: 2024

Venue: Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: https://doi.org/10.1016/j.phymed.2024.155883

Paper Cardioprotective effects of curcumin against Diabetic Cardiomyopathies: A systematic review and meta-analysis of preclinical studies.

Wang, Wujiao; Chang, Peifen; Jin, Jialin et al. · 2024 · Phytomedicine : international journal of phytotherapy and phytopharmacology · DOI

Full title: Cardioprotective effects of curcumin against Diabetic Cardiomyopathies: A systematic review and meta-analysis of preclinical studies.

Authors: Wang, Wujiao; Chang, Peifen; Jin, Jialin; Pu, Fenglan; Li, Dan; Bai, Ying; Dong, Ke; Yang, Qingshu; Li, Tianli

Year: 2024

Venue: Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: https://doi.org/10.1016/j.phymed.2024.155619

Paper Natural products that alleviate depression: The putative role of autophagy.

Zhou, Yunfeng; Nan, Fengwei; Zhang, Qianwen et al. · 2024 · Pharmacology & therapeutics · DOI

Full title: Natural products that alleviate depression: The putative role of autophagy.

Authors: Zhou, Yunfeng; Nan, Fengwei; Zhang, Qianwen; Xu, Wangjun; Fang, Shaojie; Liu, Ke; Zhao, Bingxin; Han, Hao; Xie, Xinmei; Qin, Changjiang; Pang, Xiaobin

Year: 2024

Venue: Pharmacology & therapeutics

DOI: https://doi.org/10.1016/j.pharmthera.2024.108731

Paper Autophagy in hemorrhagic stroke: Mechanisms and clinical implications.

Li, Haiying; Wu, Jiang; Shen, Haitao et al. · 2018 · Progress in neurobiology · DOI

Full title: Autophagy in hemorrhagic stroke: Mechanisms and clinical implications.

Authors: Li, Haiying; Wu, Jiang; Shen, Haitao; Yao, Xiyang; Liu, Chenglin; Pianta, S; Han, J; Borlongan, C V; Chen, Gang

Year: 2018

Venue: Progress in neurobiology

DOI: https://doi.org/10.1016/j.pneurobio.2017.04.002

Paper Demethylzeylasteral ameliorates podocyte damage in murine lupus by inhibiting inflammation and enhancing autophagy.

Shen, Pan; Deng, Xuan; Chen, Zhe et al. · 2024 · Phytomedicine : international journal of phytotherapy and phytopharmacology · DOI

Full title: Demethylzeylasteral ameliorates podocyte damage in murine lupus by inhibiting inflammation and enhancing autophagy.

Authors: Shen, Pan; Deng, Xuan; Chen, Zhe; Chen, Min; Han, Liang; Chen, Xiaoqi; Tu, Shenghao

Year: 2024

Venue: Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: https://doi.org/10.1016/j.phymed.2024.155966

Paper Timosaponin B-II attenuates cerebral ischemia injury by enhancing Parkin-mediated mitophagy.

Liu, Yueyang; Shang, Hanxiao; Zhang, Lu et al. · 2025 · Phytomedicine : international journal of phytotherapy and phytopharmacology · DOI

Full title: Timosaponin B-II attenuates cerebral ischemia injury by enhancing Parkin-mediated mitophagy.

Authors: Liu, Yueyang; Shang, Hanxiao; Zhang, Lu; Fu, Rong; Li, Yayi; Wang, Zhuo; Zhen, Yanru; Zhang, Qi; Zhao, Yang; Wang, Guannan; Zhou, Ming-Sheng

Year: 2025

Venue: Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: https://doi.org/10.1016/j.phymed.2025.157580

Paper Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigrum ssp. abietinum in Caenorhabditis elegans.

Krustanova, Slaveya; Todorova, Monika N; Gerasimova, Vanya et al. · 2026 · Phytomedicine : international journal of phytotherapy and phytopharmacology · DOI

Full title: Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigrum ssp. abietinum in Caenorhabditis elegans.

Authors: Krustanova, Slaveya; Todorova, Monika N; Gerasimova, Vanya; Savova, Martina S; Stoyanov, Stoyan; Popova, Milena P; Georgiev, Milen I; Alipieva, Kalina

Year: 2026

Venue: Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: https://doi.org/10.1016/j.phymed.2026.157944

Paper Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.

Yen, Yu-Ting; Yang, Hong-Ren; Lo, Hung-Chieh et al. · 2013 · Surgery · DOI

Full title: Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.

Authors: Yen, Yu-Ting; Yang, Hong-Ren; Lo, Hung-Chieh; Hsieh, Ya-Ching; Tsai, Shih-Chang; Hong, Chia-Wen; Hsieh, Chi-Hsun

Year: 2013

Venue: Surgery

DOI: https://doi.org/10.1016/j.surg.2012.11.021

Paper Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B.

Xu, Jian; Wu, Yihua; Lu, Guang et al. · 2017 · Redox biology · DOI

Full title: Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B.

Authors: Xu, Jian; Wu, Yihua; Lu, Guang; Xie, Shujun; Ma, Zhongjun; Chen, Zhe; Shen, Han-Ming; Xia, Dajing

Year: 2017

Venue: Redox biology

DOI: https://doi.org/10.1016/j.redox.2017.02.017

Paper Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.

Zhao, Xiuling; Wang, Lei; Huang, Shiqin et al. · 2025 · Reproductive toxicology (Elmsford, N.Y.) · DOI

Full title: Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.

Authors: Zhao, Xiuling; Wang, Lei; Huang, Shiqin; Liu, Lin; Wang, Xiaorong; Pu, Liping; Chen, Hao; Nie, Junyu

Year: 2025

Venue: Reproductive toxicology (Elmsford, N.Y.)

DOI: https://doi.org/10.1016/j.reprotox.2025.109048

Paper Regulation of autophagy by stress-responsive transcription factors.

Pietrocola, Federico; Izzo, Valentina; Niso-Santano, Mireia et al. · 2013 · Seminars in cancer biology · DOI

Full title: Regulation of autophagy by stress-responsive transcription factors.

Authors: Pietrocola, Federico; Izzo, Valentina; Niso-Santano, Mireia; Vacchelli, Erika; Galluzzi, Lorenzo; Maiuri, Maria Chiara; Kroemer, Guido

Year: 2013

Venue: Seminars in cancer biology

DOI: https://doi.org/10.1016/j.semcancer.2013.05.008

Paper The autophagy-NAD axis in longevity and disease.

Wilson, Niall; Kataura, Tetsushi; Korsgen, Miriam E et al. · 2023 · Trends in cell biology · DOI

Full title: The autophagy-NAD axis in longevity and disease.

Authors: Wilson, Niall; Kataura, Tetsushi; Korsgen, Miriam E; Sun, Congxin; Sarkar, Sovan; Korolchuk, Viktor I

Year: 2023

Venue: Trends in cell biology

DOI: https://doi.org/10.1016/j.tcb.2023.02.004

Paper Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.

Zhou, Guoyu; Tang, Sha; Yang, Lu et al. · 2019 · Toxicology and applied pharmacology · DOI

Full title: Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.

Authors: Zhou, Guoyu; Tang, Sha; Yang, Lu; Niu, Qiang; Chen, Jingwen; Xia, Tao; Wang, Sumei; Wang, Mengwei; Zhao, Qian; Liu, Ling; Li, Pei; Dong, Lixin; Yang, Kedi; Zhang, Shun; Wang, Aiguo

Year: 2019

Venue: Toxicology and applied pharmacology

DOI: https://doi.org/10.1016/j.taap.2019.114608

Paper Age-related macular degeneration and neurodegenerative disorders: Shared pathways in complex interactions.

Jabbehdari, Sayena; Oganov, Anthony C; Rezagholi, Fateme et al. · 2024 · Survey of ophthalmology · DOI

Full title: Age-related macular degeneration and neurodegenerative disorders: Shared pathways in complex interactions.

Authors: Jabbehdari, Sayena; Oganov, Anthony C; Rezagholi, Fateme; Mohammadi, Soheil; Harandi, Hamid; Yazdanpanah, Ghasem; Arevalo, J Fernando

Year: 2024

Venue: Survey of ophthalmology

DOI: https://doi.org/10.1016/j.survophthal.2023.11.003

Paper The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.

Martini-Stoica, Heidi; Xu, Yin; Ballabio, Andrea et al. · 2016 · Trends in neurosciences · DOI

Full title: The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.

Authors: Martini-Stoica, Heidi; Xu, Yin; Ballabio, Andrea; Zheng, Hui

Year: 2016

Venue: Trends in neurosciences

DOI: https://doi.org/10.1016/j.tins.2016.02.002

Paper Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway.

Hou, Huan; Yang, Yaping; Chen, Rong et al. · 2023 · Toxicology in vitro : an international journal published in association with BIBRA · DOI

Full title: Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway.

Authors: Hou, Huan; Yang, Yaping; Chen, Rong; Guo, Zhiping

Year: 2023

Venue: Toxicology in vitro : an international journal published in association with BIBRA

DOI: https://doi.org/10.1016/j.tiv.2023.105704

Paper Rifampicin attenuates rotenone-treated microglia inflammation via improving lysosomal function.

Liang, Yanran; Zheng, Dezhi; Peng, Sudan et al. · 2020 · Toxicology in vitro : an international journal published in association with BIBRA · DOI

Full title: Rifampicin attenuates rotenone-treated microglia inflammation via improving lysosomal function.

Authors: Liang, Yanran; Zheng, Dezhi; Peng, Sudan; Lin, Danyu; Jing, Xiuna; Zeng, Zhifen; Chen, Ying; Huang, Kaixun; Xie, Yingyu; Zhou, Tianen; Tao, Enxiang

Year: 2020

Venue: Toxicology in vitro : an international journal published in association with BIBRA

DOI: https://doi.org/10.1016/j.tiv.2019.104690

Paper Autophagy activated by GR/miR-421-3p/mTOR pathway as a compensatory mechanism participates in chondrodysplasia induced by prenatal caffeine exposure in male fetal rats.

Han, Hui; Shi, Huasong; Jiang, Lingxiao et al. · 2024 · Toxicology letters · DOI

Full title: Autophagy activated by GR/miR-421-3p/mTOR pathway as a compensatory mechanism participates in chondrodysplasia induced by prenatal caffeine exposure in male fetal rats.

Authors: Han, Hui; Shi, Huasong; Jiang, Lingxiao; Zhang, Dingmei; Wang, Hui; Li, Jing; Chen, Liaobin

Year: 2024

Venue: Toxicology letters

DOI: https://doi.org/10.1016/j.toxlet.2024.05.010

Paper Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitro.

Han, Yu; Wang, Chongyang; Lu, Kejia et al. · 2024 · Veterinary microbiology · DOI

Full title: Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitro.

Authors: Han, Yu; Wang, Chongyang; Lu, Kejia; Dong, Xiaoyu; Chang, Zhengwu; Zhang, Riteng; Hou, Qili; Wang, Xinglong; Xiao, Sa; Liu, Haijin; Yang, Zengqi

Year: 2024

Venue: Veterinary microbiology

DOI: https://doi.org/10.1016/j.vetmic.2023.109972

Paper Potential autophagy enhancers protect against fipronil-induced apoptosis in SH-SY5Y cells.

Park, Jae Hyeon; Lee, Jeong Eun; Lee, Soo-Jin et al. · 2013 · Toxicology letters · DOI

Full title: Potential autophagy enhancers protect against fipronil-induced apoptosis in SH-SY5Y cells.

Authors: Park, Jae Hyeon; Lee, Jeong Eun; Lee, Soo-Jin; Park, Soo Jin; Park, Kyung Hun; Jeong, Mihye; Koh, Hyun Chul

Year: 2013

Venue: Toxicology letters

DOI: https://doi.org/10.1016/j.toxlet.2013.08.015

Paper The FoxO-Autophagy Axis in Health and Disease.

Cheng, Zhiyong · 2019 · Trends in endocrinology and metabolism: TEM · DOI

Full title: The FoxO-Autophagy Axis in Health and Disease.

Authors: Cheng, Zhiyong

Year: 2019

Venue: Trends in endocrinology and metabolism: TEM

DOI: https://doi.org/10.1016/j.tem.2019.07.009

Paper Inflammation as a central mechanism in Alzheimer's disease

Kinney, Jefferson W.; Bemiller, Shane M.; Murtishaw, Andrew S. et al. · 2018 · Alzheimer s & Dementia Translational Research & Clinical Interventions · DOI

Full title: Inflammation as a central mechanism in Alzheimer's disease

Authors: Kinney, Jefferson W.; Bemiller, Shane M.; Murtishaw, Andrew S.; Leisgang, Amanda M.; Salazar, Arnold; Lamb, Bruce T.

Year: 2018

Venue: Alzheimer s & Dementia Translational Research & Clinical Interventions

DOI: https://doi.org/10.1016/j.trci.2018.06.014

Paper The induction of AMPK-dependent autophagy leads to P53 degradation and affects cell growth and migration in kidney cancer cells.

Patergnani, Simone; Guzzo, Sonia; Mangolini, Alessandra et al. · 2020 · Experimental cell research · DOI

Full title: The induction of AMPK-dependent autophagy leads to P53 degradation and affects cell growth and migration in kidney cancer cells.

Authors: Patergnani, Simone; Guzzo, Sonia; Mangolini, Alessandra; dell'Atti, Lucio; Pinton, Paolo; Aguiari, Gianluca

Year: 2020

Venue: Experimental cell research

DOI: https://doi.org/10.1016/j.yexcr.2020.112190

Paper Human endogenous retrovirus W family envelope protein (ERVWE1) regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia.

Zhang, Jiahang; Wang, Huiling; Xue, Xing et al. · 2025 · Virologica Sinica · DOI

Full title: Human endogenous retrovirus W family envelope protein (ERVWE1) regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia.

Authors: Zhang, Jiahang; Wang, Huiling; Xue, Xing; Wu, Xiulin; Li, Wenshi; Lv, Zhao; Su, Yaru; Zhang, Mengqi; Zhao, Kexin; Zhang, Xu; Jia, Chen; Zhu, Fan

Year: 2025

Venue: Virologica Sinica

DOI: https://doi.org/10.1016/j.virs.2025.05.007

Paper Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.

Li, Wen-Wen; Wang, Hai-Jie; Tan, Yu-Zhen et al. · 2021 · Experimental cell research · DOI

Full title: Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.

Authors: Li, Wen-Wen; Wang, Hai-Jie; Tan, Yu-Zhen; Wang, Yong-Li; Yu, Shu-Na; Li, Zhi-Hua

Year: 2021

Venue: Experimental cell research

DOI: https://doi.org/10.1016/j.yexcr.2021.112585

Paper Staying young at heart: autophagy and adaptation to cardiac aging.

Leon, Leonardo J; Gustafsson, Åsa B · 2016 · Journal of molecular and cellular cardiology · DOI

Full title: Staying young at heart: autophagy and adaptation to cardiac aging.

Authors: Leon, Leonardo J; Gustafsson, Åsa B

Year: 2016

Venue: Journal of molecular and cellular cardiology

DOI: https://doi.org/10.1016/j.yjmcc.2015.11.006

Paper The interplay between autophagy and mitochondrial dysfunction in oxidative stress-induced cardiac aging and pathology.

Wohlgemuth, Stephanie E; Calvani, Riccardo; Marzetti, Emanuele · 2014 · Journal of molecular and cellular cardiology · DOI

Full title: The interplay between autophagy and mitochondrial dysfunction in oxidative stress-induced cardiac aging and pathology.

Authors: Wohlgemuth, Stephanie E; Calvani, Riccardo; Marzetti, Emanuele

Year: 2014

Venue: Journal of molecular and cellular cardiology

DOI: https://doi.org/10.1016/j.yjmcc.2014.03.007

Paper Hernandezine promotes cancer cell apoptosis and disrupts the lysosomal acidic environment and cathepsin D maturation.

Feng, Qianwen; Sun, Lu; Sualeh, Muhammad Jibran et al. · 2024 · Chinese journal of natural medicines · DOI

Full title: Hernandezine promotes cancer cell apoptosis and disrupts the lysosomal acidic environment and cathepsin D maturation.

Authors: Feng, Qianwen; Sun, Lu; Sualeh, Muhammad Jibran; Zhao, Qingli; Zhao, Songji; Cui, Zhengguo; Inadera, Hidekuni

Year: 2024

Venue: Chinese journal of natural medicines

DOI: https://doi.org/10.1016/S1875-5364(24)60638-2

Paper HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy.

Shu, Bo; Zhou, Yingxia; Liang, Qingchun et al. · 2021 · Experimental and molecular pathology · DOI

Full title: HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy.

Authors: Shu, Bo; Zhou, Yingxia; Liang, Qingchun; He, Chao; Li, Fazhao

Year: 2021

Venue: Experimental and molecular pathology

DOI: https://doi.org/10.1016/j.yexmp.2021.104691

Paper Does autophagy worsen or improve the survival of dopaminergic neurons?

Pasquali, Livia; Ruggieri, Stefano; Murri, Luigi et al. · 2009 · Parkinsonism & related disorders · DOI

Full title: Does autophagy worsen or improve the survival of dopaminergic neurons?

Authors: Pasquali, Livia; Ruggieri, Stefano; Murri, Luigi; Paparelli, Antonio; Fornai, Francesco

Year: 2009

Venue: Parkinsonism & related disorders

DOI: https://doi.org/10.1016/S1353-8020(09)70830-2

Paper Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

Sarkar, Sovan; Ravikumar, Brinda; Rubinsztein, David C · 2009 · Methods in enzymology · DOI

Full title: Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

Authors: Sarkar, Sovan; Ravikumar, Brinda; Rubinsztein, David C

Year: 2009

Venue: Methods in enzymology

DOI: https://doi.org/10.1016/S0076-6879(08)04005-6

Paper Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.

Wu, Xiaoqian; Qin, Yuyan; Zhu, Xiaoyan et al. · 2018 · Journal of molecular and cellular cardiology · DOI

Full title: Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.

Authors: Wu, Xiaoqian; Qin, Yuyan; Zhu, Xiaoyan; Liu, Dajun; Chen, Fajiang; Xu, Suowen; Zheng, Dechong; Zhou, You; Luo, Jiandong

Year: 2018

Venue: Journal of molecular and cellular cardiology

DOI: https://doi.org/10.1016/j.yjmcc.2018.08.018

Paper The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.

Tang, Weilong; Yin, Xiaoyu; Liu, Kunyu et al. · 2024 · Experimental cell research · DOI

Full title: The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.

Authors: Tang, Weilong; Yin, Xiaoyu; Liu, Kunyu; Shao, Tuo; Gao, Qichang; Shen, Hongtao; Zhong, Xin; Zhang, Zhenyu

Year: 2024

Venue: Experimental cell research

DOI: https://doi.org/10.1016/j.yexcr.2024.114261

Paper NVP-BEZ235 enhances autophagy and ameliorates cognitive deficits by targeting tauopathies.

Alsharif, Ifat · 2025 · Experimental and molecular pathology · DOI

Full title: NVP-BEZ235 enhances autophagy and ameliorates cognitive deficits by targeting tauopathies.

Authors: Alsharif, Ifat

Year: 2025

Venue: Experimental and molecular pathology

DOI: https://doi.org/10.1016/j.yexmp.2025.104988

Paper Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy.

Su, Lili; Guo, Pengli; Guo, Xiangjuan et al. · 2024 · Chinese journal of natural medicines · DOI

Full title: Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy.

Authors: Su, Lili; Guo, Pengli; Guo, Xiangjuan; He, Zhongmei; Zhao, Yan; Zong, Ying; Li, Jianming; Chen, Weijia; DU, Rui

Year: 2024

Venue: Chinese journal of natural medicines

DOI: https://doi.org/10.1016/S1875-5364(24)60654-0

Paper Alkaline Phosphatase and ATG4B Sequentially Activated Fluorescent Probe for Cancer Cell-Specific Live Imaging of Autophagy.

Zheng, Yaxin; Ma, Xinyue; Zhou, Shuyao et al. · 2025 · Analytical chemistry · DOI

Full title: Alkaline Phosphatase and ATG4B Sequentially Activated Fluorescent Probe for Cancer Cell-Specific Live Imaging of Autophagy.

Authors: Zheng, Yaxin; Ma, Xinyue; Zhou, Shuyao; Lei, Wenwen; Luo, Xuan; Zhou, Lei; Xu, Keming; Zhong, Wenying

Year: 2025

Venue: Analytical chemistry

DOI: https://doi.org/10.1021/acs.analchem.4c06950

Paper Advances in Plant Polysaccharides as Antiaging Agents: Effects and Signaling Mechanisms.

Deng, Rou; Wang, Fang; Wang, Luanfeng et al. · 2023 · Journal of agricultural and food chemistry · DOI

Full title: Advances in Plant Polysaccharides as Antiaging Agents: Effects and Signaling Mechanisms.

Authors: Deng, Rou; Wang, Fang; Wang, Luanfeng; Xiong, Ling; Shen, Xinchun; Song, Haizhao

Year: 2023

Venue: Journal of agricultural and food chemistry

DOI: https://doi.org/10.1021/acs.jafc.3c00493

Paper Autophagy Promotes Memory Formation.

Tripathi, Timir; Kalita, Parismita; Martins, Ralph et al. · 2019 · ACS chemical neuroscience · DOI

Full title: Autophagy Promotes Memory Formation.

Authors: Tripathi, Timir; Kalita, Parismita; Martins, Ralph; Bharadwaj, Prashant

Year: 2019

Venue: ACS chemical neuroscience

DOI: https://doi.org/10.1021/acschemneuro.9b00317

Paper Lycopene Regulates Macrophage Immune Response through the Autophagy Pathway Mediated by RIPK1.

Yao, Yupei; Liu, Xiaoran; Niu, Xiaoyan et al. · 2024 · Journal of agricultural and food chemistry · DOI

Full title: Lycopene Regulates Macrophage Immune Response through the Autophagy Pathway Mediated by RIPK1.

Authors: Yao, Yupei; Liu, Xiaoran; Niu, Xiaoyan; Li, Yaping; Han, Lirong

Year: 2024

Venue: Journal of agricultural and food chemistry

DOI: https://doi.org/10.1021/acs.jafc.4c02531

Paper Alginate-Derived Mannuronate Oligosaccharide Attenuates Tauopathy through Enhancing Autophagy.

Bi, Decheng; Xiao, Shifeng; Lin, Zhijian et al. · 2021 · Journal of agricultural and food chemistry · DOI

Full title: Alginate-Derived Mannuronate Oligosaccharide Attenuates Tauopathy through Enhancing Autophagy.

Authors: Bi, Decheng; Xiao, Shifeng; Lin, Zhijian; Yao, Lijun; Fang, Weishan; Wu, Yan; Xu, Hong; Lu, Jun; Xu, Xu

Year: 2021

Venue: Journal of agricultural and food chemistry

DOI: https://doi.org/10.1021/acs.jafc.1c00394

Paper Ginsenoside-Rh2 Promotes Functional Recovery after Spinal Cord Injury by Enhancing TFEB-Mediated Autophagy.

Liu, Rongjie; Jiang, Liting; Chen, Yituo et al. · 2024 · Journal of agricultural and food chemistry · DOI

Full title: Ginsenoside-Rh2 Promotes Functional Recovery after Spinal Cord Injury by Enhancing TFEB-Mediated Autophagy.

Authors: Liu, Rongjie; Jiang, Liting; Chen, Yituo; Shao, Jiaqin; Chen, Kongbin; Li, Xiang; Lv, Junlei; Cai, Wanta; Cai, Haoxu; Zhu, Zhefan; Wang, Chenggui; Zhou, Kailiang; Huang, Jinfeng; Xiao, Jian; Ni, Wenfei; Wu, Chenyu

Year: 2024

Venue: Journal of agricultural and food chemistry

DOI: https://doi.org/10.1021/acs.jafc.4c02379

Paper Conjugation with Phenylalanine Enhances Autophagy-Inducing Activity of (-)-Epigallocatechin Gallate in Hepatic Cells.

Lee, Yong Min; Kim, Mi Kyoung; Choo, Hyunah et al. · 2018 · Journal of agricultural and food chemistry · DOI

Full title: Conjugation with Phenylalanine Enhances Autophagy-Inducing Activity of (-)-Epigallocatechin Gallate in Hepatic Cells.

Authors: Lee, Yong Min; Kim, Mi Kyoung; Choo, Hyunah; Chong, Youhoon

Year: 2018

Venue: Journal of agricultural and food chemistry

DOI: https://doi.org/10.1021/acs.jafc.8b05361

Paper Designed Polymer Micelle for Clearing Amyloid Protein Aggregates via Up-Regulated Autophagy.

Debnath, Koushik; Jana, Nihar R; Jana, Nikhil R · 2019 · ACS biomaterials science & engineering · DOI

Full title: Designed Polymer Micelle for Clearing Amyloid Protein Aggregates via Up-Regulated Autophagy.

Authors: Debnath, Koushik; Jana, Nihar R; Jana, Nikhil R

Year: 2019

Venue: ACS biomaterials science & engineering

DOI: https://doi.org/10.1021/acsbiomaterials.8b01196

Paper Dysregulation of Host Histone Acetylation by Acinetobacter baumannii: A Novel Mechanism for Autophagy Inhibition and Bacterial Survival.

Singothu, Siva; Kinkar, Dhanshree; Vulli, Divyasree et al. · 2025 · ACS infectious diseases · DOI

Full title: Dysregulation of Host Histone Acetylation by Acinetobacter baumannii: A Novel Mechanism for Autophagy Inhibition and Bacterial Survival.

Authors: Singothu, Siva; Kinkar, Dhanshree; Vulli, Divyasree; Brahma, Umarani; Bandaru, Rajiv Kumar; Bhandari, Vasundhra

Year: 2025

Venue: ACS infectious diseases

DOI: https://doi.org/10.1021/acsinfecdis.5c00080

Paper Ferroptosis Induced by Pollutants: An Emerging Mechanism in Environmental Toxicology.

Yang, Lili; Cai, Xiaoming; Li, Ruibin · 2024 · Environmental science & technology · DOI

Full title: Ferroptosis Induced by Pollutants: An Emerging Mechanism in Environmental Toxicology.

Authors: Yang, Lili; Cai, Xiaoming; Li, Ruibin

Year: 2024

Venue: Environmental science & technology

DOI: https://doi.org/10.1021/acs.est.3c06127

Paper An Efficient Regioselective Synthesis of 8-Formylhomoisoflavonoids with Neuroprotective Activity by Enhancing Autophagy.

Li, Jie; Yang, Fan; Zeng, Lin-Wei et al. · 2021 · Journal of natural products · DOI

Full title: An Efficient Regioselective Synthesis of 8-Formylhomoisoflavonoids with Neuroprotective Activity by Enhancing Autophagy.

Authors: Li, Jie; Yang, Fan; Zeng, Lin-Wei; Zhang, Fang-Min; Zhou, Chang-Xin; Gan, Li-She

Year: 2021

Venue: Journal of natural products

DOI: https://doi.org/10.1021/acs.jnatprod.0c00830

Paper Application and interpretation of current autophagy inhibitors and activators

Yang, Yaping; Hu, Li‐Fang; Zheng, Hui-fen et al. · 2013 · Acta Pharmacologica Sinica · DOI

Full title: Application and interpretation of current autophagy inhibitors and activators

Authors: Yang, Yaping; Hu, Li‐Fang; Zheng, Hui-fen; Mao, Chengjie; Hu, Weidong; Xiong, Kangping; Wang, Fen; Liu, Chun‐Feng

Year: 2013

Venue: Acta Pharmacologica Sinica

DOI: https://doi.org/10.1038/aps.2013.5

Paper Modulating polyplex-mediated gene transfection by small-molecule regulators of autophagy.

Zhong, Xiao; Panus, David; Ji, Weihang et al. · 2015 · Molecular pharmaceutics · DOI

Full title: Modulating polyplex-mediated gene transfection by small-molecule regulators of autophagy.

Authors: Zhong, Xiao; Panus, David; Ji, Weihang; Wang, Chun

Year: 2015

Venue: Molecular pharmaceutics

DOI: https://doi.org/10.1021/mp500764p

Paper miR-873-5p Suppression Reinvigorates Aging Mesenchymal Stem Cells and Improves Cardiac Repair after Myocardial Infarction.

Zhu, Wenwu; Du, Wei; Duan, Rui et al. · 2024 · ACS pharmacology & translational science · DOI

Full title: miR-873-5p Suppression Reinvigorates Aging Mesenchymal Stem Cells and Improves Cardiac Repair after Myocardial Infarction.

Authors: Zhu, Wenwu; Du, Wei; Duan, Rui; Liu, Yan; Zong, Bin; Jin, Xin; Dong, Zishuang; Wang, Hui; Shahab, Siyamak; Wang, Haoran; Hong, Yimei; Han, Bing

Year: 2024

Venue: ACS pharmacology & translational science

DOI: https://doi.org/10.1021/acsptsci.3c00293

Paper Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.

Roberts, D J; Miyamoto, S · 2015 · Cell death and differentiation · DOI

Full title: Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.

Authors: Roberts, D J; Miyamoto, S

Year: 2015

Venue: Cell death and differentiation

DOI: https://doi.org/10.1038/cdd.2014.173

Paper Rhynchophylla total alkaloid rescues autophagy, decreases oxidative stress and improves endothelial vasodilation in spontaneous hypertensive rats.

Li, Chao; Jiang, Feng; Li, Yun-Lun et al. · 2018 · Acta pharmacologica Sinica · DOI

Full title: Rhynchophylla total alkaloid rescues autophagy, decreases oxidative stress and improves endothelial vasodilation in spontaneous hypertensive rats.

Authors: Li, Chao; Jiang, Feng; Li, Yun-Lun; Jiang, Yue-Hua; Yang, Wen-Qing; Sheng, Jie; Xu, Wen-Juan; Zhu, Qing-Jun

Year: 2018

Venue: Acta pharmacologica Sinica

DOI: https://doi.org/10.1038/aps.2017.120

Paper Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1.

Joshi, A; Iyengar, R; Joo, J H et al. · 2016 · Cell death and differentiation · DOI

Full title: Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1.

Authors: Joshi, A; Iyengar, R; Joo, J H; Li-Harms, X J; Wright, C; Marino, R; Winborn, B J; Phillips, A; Temirov, J; Sciarretta, S; Kriwacki, R; Peng, J; Shelat, A; Kundu, M

Year: 2016

Venue: Cell death and differentiation

DOI: https://doi.org/10.1038/cdd.2015.88

Paper The far-reaching scope of neuroinflammation after traumatic brain injury

Simon, Dennis; McGeachy, Mandy J.; Bayır, Hülya et al. · 2017 · Nature Reviews Neurology · DOI

Full title: The far-reaching scope of neuroinflammation after traumatic brain injury

Authors: Simon, Dennis; McGeachy, Mandy J.; Bayır, Hülya; Clark, Robert S. B.; Loane, David J.; Kochanek, Patrick M.

Year: 2017

Venue: Nature Reviews Neurology

DOI: https://doi.org/10.1038/nrneurol.2017.13

Paper Targeting phospholipase D in cancer, infection and neurodegenerative disorders

Brown, H. Alex; Thomas, Paul G.; Lindsley, Craig W. · 2017 · Nature Reviews Drug Discovery · DOI

Full title: Targeting phospholipase D in cancer, infection and neurodegenerative disorders

Authors: Brown, H. Alex; Thomas, Paul G.; Lindsley, Craig W.

Year: 2017

Venue: Nature Reviews Drug Discovery

DOI: https://doi.org/10.1038/nrd.2016.252

Paper The many faces of α-synuclein: from structure and toxicity to therapeutic target

Lashuel, Hilal A.; Overk, Cassia; Oueslati, Abid et al. · 2012 · Nature reviews. Neuroscience · DOI

Full title: The many faces of α-synuclein: from structure and toxicity to therapeutic target

Authors: Lashuel, Hilal A.; Overk, Cassia; Oueslati, Abid; Masliah, Eliezer

Year: 2012

Venue: Nature reviews. Neuroscience

DOI: https://doi.org/10.1038/nrn3406

Paper Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.

Zhu, Zhou; Liu, Liang-Feng; Su, Cheng-Fu et al. · 2022 · Acta pharmacologica Sinica · DOI

Full title: Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.

Authors: Zhu, Zhou; Liu, Liang-Feng; Su, Cheng-Fu; Liu, Jia; Tong, Benjamin Chun-Kit; Iyaswamy, Ashok; Krishnamoorthi, Senthilkumar; Sreenivasmurthy, Sravan Gopalkrishnashetty; Guan, Xin-Jie; Kan, Yu-Xuan; Xie, Wen-Jian; Zhao, Chen-Liang; Cheung, King-Ho; Lu, Jia-Hong; Tan, Jie-Qiong; Zhang, Hong-Jie; Song, Ju-Xian; Li, Min

Year: 2022

Venue: Acta pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-022-00871-0

Paper CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.

Dong, Jian; Zhang, Kai-Jia; Li, Gao-Cai et al. · 2022 · Acta pharmacologica Sinica · DOI

Full title: CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.

Authors: Dong, Jian; Zhang, Kai-Jia; Li, Gao-Cai; Chen, Xing-Ren; Lin, Jia-Jia; Li, Jia-Wei; Lv, Zhong-Yang; Deng, Zhao-Zhi; Dai, Jin; Cao, Wangsen; Jiang, Qing

Year: 2022

Venue: Acta pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-021-00782-6

Paper New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease

Zhang, Feng; Zhong, Rujia; Cheng, Cheng et al. · 2020 · Acta Pharmacologica Sinica · DOI

Full title: New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease

Authors: Zhang, Feng; Zhong, Rujia; Cheng, Cheng; Li, Song; Le, Weidong

Year: 2020

Venue: Acta Pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-020-00565-5

Paper Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy.

Lin, Zhen; Li, Lu-Yao; Chen, Lu et al. · 2024 · Acta pharmacologica Sinica · DOI

Full title: Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy.

Authors: Lin, Zhen; Li, Lu-Yao; Chen, Lu; Jin, Chen; Li, Yue; Yang, Lan; Li, Chang-Zhou; Qi, Cai-Yu; Gan, Yu-Yang; Zhang, Jia-Rui; Wang, Piao; Ni, Li-Bin; Wang, Gao-Feng

Year: 2024

Venue: Acta pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-023-01193-5

Paper Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation

Kou, Jie‐Jian; Shi, Jun-Zhuo; He, Yangyang et al. · 2021 · Acta Pharmacologica Sinica · DOI

Full title: Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation

Authors: Kou, Jie‐Jian; Shi, Jun-Zhuo; He, Yangyang; Hao, Jiaojiao; Zhang, Haiyu; Dong-mei, Luo; Song, Junke; Yan, Yi; Xie, Xinmei; Du, Guanhua; Pang, Xiaobin

Year: 2021

Venue: Acta Pharmacologica Sinica

DOI: https://doi.org/10.1038/s41401-021-00702-8

Paper The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease

Tüfekçi, Kemal Uğur; Bayin, Ezgi Civi; Genç, Şermin et al. · 2011 · Parkinson s Disease · DOI

Full title: The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease

Authors: Tüfekçi, Kemal Uğur; Bayin, Ezgi Civi; Genç, Şermin; Genç, Kürşad

Year: 2011

Venue: Parkinson s Disease

DOI: https://doi.org/10.4061/2011/314082

Paper Protein Kinases and Phosphatases in the Control of Cell Fate

Bononi, Angela; Agnoletto, Chiara; Marchi, Elena De et al. · 2011 · Enzyme Research · DOI

Full title: Protein Kinases and Phosphatases in the Control of Cell Fate

Authors: Bononi, Angela; Agnoletto, Chiara; Marchi, Elena De; Marchi, Saverio; Patergnani, Simone; Bonora, Massimo; Giorgi, Carlotta; Missiroli, Sonia; Poletti, Federica; Rimessi, Alessandro; Pinton, Paolo

Year: 2011

Venue: Enzyme Research

DOI: https://doi.org/10.4061/2011/329098

Paper Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells.

Kim, Hee Ju; Kim, Joonki; Kang, Ki Sung et al. · 2014 · Biomolecules & therapeutics · DOI

Full title: Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells.

Authors: Kim, Hee Ju; Kim, Joonki; Kang, Ki Sung; Lee, Keun Taik; Yang, Hyun Ok

Year: 2014

Venue: Biomolecules & therapeutics

DOI: https://doi.org/10.4062/biomolther.2014.068

Paper Small Changes Huge Impact: The Role of Protein Posttranslational Modifications in Cellular Homeostasis and Disease

Karve, Tejaswita M.; Cheema, Amrita K. · 2011 · Journal of Amino Acids · DOI

Full title: Small Changes Huge Impact: The Role of Protein Posttranslational Modifications in Cellular Homeostasis and Disease

Authors: Karve, Tejaswita M.; Cheema, Amrita K.

Year: 2011

Venue: Journal of Amino Acids

DOI: https://doi.org/10.4061/2011/207691

Paper Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.

Liang, Hao-Yu; Peng, Fan; Pan, Min-Jia et al. · 2023 · Asian journal of andrology · DOI

Full title: Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.

Authors: Liang, Hao-Yu; Peng, Fan; Pan, Min-Jia; Liao, Sen-Lin; Wei, Cun; Wei, Guan-Yang; Xie, Xiao; Xue, Kang-Yi; Chen, Ming-Kun; Yang, Jian-Kun; Guo, Wen-Bin; Liu, Cun-Dong; Zhou, Qi-Zhao

Year: 2023

Venue: Asian journal of andrology

DOI: https://doi.org/10.4103/aja202286

Paper Autophagy-targeting modulation to promote peripheral nerve regeneration.

Chen, Yan; Deng, Hongxia; Zhang, Nannan · 2025 · Neural regeneration research · DOI

Full title: Autophagy-targeting modulation to promote peripheral nerve regeneration.

Authors: Chen, Yan; Deng, Hongxia; Zhang, Nannan

Year: 2025

Venue: Neural regeneration research

DOI: https://doi.org/10.4103/NRR.NRR-D-23-01948

Paper Autophagy can be a killer even in apoptosis-competent cells.

Guillon-Munos, Audrey; van Bemmelen, Miguel X P; Clarke, Peter G H · 2006 · Autophagy · DOI

Full title: Autophagy can be a killer even in apoptosis-competent cells.

Authors: Guillon-Munos, Audrey; van Bemmelen, Miguel X P; Clarke, Peter G H

Year: 2006

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.2.2.2443

Paper Davunetide promotes structural and functional recovery of the injured spinal cord by promoting autophagy.

Chen, Yituo; Liu, Rongjie; Cai, Wanta et al. · 2025 · Neural regeneration research · DOI

Full title: Davunetide promotes structural and functional recovery of the injured spinal cord by promoting autophagy.

Authors: Chen, Yituo; Liu, Rongjie; Cai, Wanta; Jiang, Liting; Chen, Kongbin; Shi, Jingwei; Lou, Junsheng; Yu, Letian; Wu, Chenyu; Yang, Liangliang; Zhou, Kailiang; Ni, Wenfei

Year: 2025

Venue: Neural regeneration research

DOI: https://doi.org/10.4103/NRR.NRR-D-24-00154

Paper Roles of neuronal lysosomes in the etiology of Parkinson's disease.

Volta, Mattia · 2024 · Neural regeneration research · DOI

Full title: Roles of neuronal lysosomes in the etiology of Parkinson's disease.

Authors: Volta, Mattia

Year: 2024

Venue: Neural regeneration research

DOI: https://doi.org/10.4103/1673-5374.390954

Paper PSPH promotes colorectal cancer growth by triggering autophagy through AMPK-ULK1 activation and enhancing tumor immune evasion.

Guan, Jiajia; Ji, Jie; Sun, Bisheng et al. · 2025 · General physiology and biophysics · DOI

Full title: PSPH promotes colorectal cancer growth by triggering autophagy through AMPK-ULK1 activation and enhancing tumor immune evasion.

Authors: Guan, Jiajia; Ji, Jie; Sun, Bisheng; Fu, Jun; Luo, Jie; Zhu, Bing

Year: 2025

Venue: General physiology and biophysics

DOI: https://doi.org/10.4149/gpb_2025019

Paper Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity.

Lotze, Michael T; Buchser, William J; Liang, Xiaoyan · 2012 · Autophagy · DOI

Full title: Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity.

Authors: Lotze, Michael T; Buchser, William J; Liang, Xiaoyan

Year: 2012

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.20752

Paper PPARGC1A/PGC-1α, TFEB and enhanced proteostasis in Huntington disease: defining regulatory linkages between energy production and protein-organelle quality control.

La Spada, Albert R · 2012 · Autophagy · DOI

Full title: PPARGC1A/PGC-1α, TFEB and enhanced proteostasis in Huntington disease: defining regulatory linkages between energy production and protein-organelle quality control.

Authors: La Spada, Albert R

Year: 2012

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.21862

Paper PERK-ing up autophagy during MYC-induced tumorigenesis.

Dey, Souvik; Tameire, Feven; Koumenis, Constantinos · 2013 · Autophagy · DOI

Full title: PERK-ing up autophagy during MYC-induced tumorigenesis.

Authors: Dey, Souvik; Tameire, Feven; Koumenis, Constantinos

Year: 2013

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.23486

Paper Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition.

Xie, Xiaolei; Le, Li; Fan, Yanxin et al. · 2012 · Autophagy · DOI

Full title: Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition.

Authors: Xie, Xiaolei; Le, Li; Fan, Yanxin; Lv, Lin; Zhang, Junjie

Year: 2012

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.20250

Paper KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC.

Puustinen, Pietri; Jäättelä, Marja · 2014 · Autophagy · DOI

Full title: KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC.

Authors: Puustinen, Pietri; Jäättelä, Marja

Year: 2014

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.29076

Paper FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.

Nakagaki, Takehiro; Satoh, Katsuya; Ishibashi, Daisuke et al. · 2013 · Autophagy · DOI

Full title: FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.

Authors: Nakagaki, Takehiro; Satoh, Katsuya; Ishibashi, Daisuke; Fuse, Takayuki; Sano, Kazunori; Kamatari, Yuji O; Kuwata, Kazuo; Shigematsu, Kazuto; Iwamaru, Yoshifumi; Takenouchi, Takato; Kitani, Hiroshi; Nishida, Noriyuki; Atarashi, Ryuichiro

Year: 2013

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.25381

Paper Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.

Castillo, Karen; Nassif, Melissa; Valenzuela, Vicente et al. · 2013 · Autophagy · DOI

Full title: Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.

Authors: Castillo, Karen; Nassif, Melissa; Valenzuela, Vicente; Rojas, Fabiola; Matus, Soledad; Mercado, Gabriela; Court, Felipe A; van Zundert, Brigitte; Hetz, Claudio

Year: 2013

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.25188

Paper Autophagy and self-preservation: a step ahead from cell plasticity?

Galliot, Brigitte · 2006 · Autophagy · DOI

Full title: Autophagy and self-preservation: a step ahead from cell plasticity?

Authors: Galliot, Brigitte

Year: 2006

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.2706

Paper TFEB: Pathogenic role and therapeutic target in Parkinson disease.

Decressac, Mickael; Björklund, Anders · 2013 · Autophagy · DOI

Full title: TFEB: Pathogenic role and therapeutic target in Parkinson disease.

Authors: Decressac, Mickael; Björklund, Anders

Year: 2013

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.25044

Paper Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy.

Bauer, Peter O; Nukina, Nobuyuki · 2009 · Autophagy · DOI

Full title: Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy.

Authors: Bauer, Peter O; Nukina, Nobuyuki

Year: 2009

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.5.5.8704

Paper Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function.

Kong, Derek K; Georgescu, Serban P; Kyriakis, John M et al. · 2010 · Autophagy · DOI

Full title: Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function.

Authors: Kong, Derek K; Georgescu, Serban P; Kyriakis, John M; Goruppi, Sandro

Year: 2010

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.6.5.12067

Paper PRKAA1/AMPKα1 is required for autophagy-dependent mitochondrial clearance during erythrocyte maturation.

Zhu, Huaiping; Foretz, Marc; Xie, Zhonglin et al. · 2014 · Autophagy · DOI

Full title: PRKAA1/AMPKα1 is required for autophagy-dependent mitochondrial clearance during erythrocyte maturation.

Authors: Zhu, Huaiping; Foretz, Marc; Xie, Zhonglin; Zhang, Miao; Zhu, Zhiren; Xing, Junjie; Leclerc, Jocelyne; Gaudry, Murielle; Viollet, Benoit; Zou, Ming-Hui

Year: 2014

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.29197

Paper mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging.

Menendez, Javier A; Vellon, Luciano; Oliveras-Ferraros, Cristina et al. · 2011 · Cell cycle (Georgetown, Tex.) · DOI

Full title: mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging.

Authors: Menendez, Javier A; Vellon, Luciano; Oliveras-Ferraros, Cristina; Cufí, Sílvia; Vazquez-Martin, Alejandro

Year: 2011

Venue: Cell cycle (Georgetown, Tex.)

DOI: https://doi.org/10.4161/cc.10.21.18128

Paper Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.

Alers, Sebastian; Löffler, Antje S; Paasch, Florian et al. · 2011 · Autophagy · DOI

Full title: Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.

Authors: Alers, Sebastian; Löffler, Antje S; Paasch, Florian; Dieterle, Alexandra M; Keppeler, Hildegard; Lauber, Kirsten; Campbell, David G; Fehrenbacher, Birgit; Schaller, Martin; Wesselborg, Sebastian; Stork, Björn

Year: 2011

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.7.12.18027

Paper Uncovering the role of Snapin in regulating autophagy-lysosomal function.

Cai, Qian; Sheng, Zu-Hang · 2011 · Autophagy · DOI

Full title: Uncovering the role of Snapin in regulating autophagy-lysosomal function.

Authors: Cai, Qian; Sheng, Zu-Hang

Year: 2011

Venue: Autophagy

DOI: https://doi.org/10.4161/auto.7.4.14682

Paper Effects of stem cell therapy on preclinical stroke.

Shannon, Gita Serafika; Rinendyaputri, Ratih; Sunarno, Sunarno et al. · 2025 · Open veterinary journal · DOI

Full title: Effects of stem cell therapy on preclinical stroke.

Authors: Shannon, Gita Serafika; Rinendyaputri, Ratih; Sunarno, Sunarno; Malik, Amarila

Year: 2025

Venue: Open veterinary journal

DOI: https://doi.org/10.5455/OVJ.2025.v15.i2.9

Paper Effects of long-term resistance exercise training on autophagy in rat skeletal muscle of chloroquine-induced sporadic inclusion body myositis.

Kwon, Insu; Lee, Youngil; Cosio-Lima, Ludmila M et al. · 2015 · Journal of exercise nutrition & biochemistry · DOI

Full title: Effects of long-term resistance exercise training on autophagy in rat skeletal muscle of chloroquine-induced sporadic inclusion body myositis.

Authors: Kwon, Insu; Lee, Youngil; Cosio-Lima, Ludmila M; Cho, Joon-Yong; Yeom, Dong-Chul

Year: 2015

Venue: Journal of exercise nutrition & biochemistry

DOI: https://doi.org/10.5717/jenb.2015.15090710

Paper Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy.

Pan, Hang-Hai; Zhou, Xin-Xin; Ma, Ying-Yu et al. · 2020 · World journal of gastroenterology · DOI

Full title: Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy.

Authors: Pan, Hang-Hai; Zhou, Xin-Xin; Ma, Ying-Yu; Pan, Wen-Sheng; Zhao, Fei; Yu, Mo-Sang; Liu, Jing-Quan

Year: 2020

Venue: World journal of gastroenterology

DOI: https://doi.org/10.3748/wjg.v26.i33.4945

Paper Trehalose delays postmenopausal osteoporosis by enhancing AKT/TFEB pathway‑dependent autophagy flow in rats.

Wang, Yongli; Li, Xingcun; Gao, Hongliang et al. · 2023 · Experimental and therapeutic medicine · DOI

Full title: Trehalose delays postmenopausal osteoporosis by enhancing AKT/TFEB pathway‑dependent autophagy flow in rats.

Authors: Wang, Yongli; Li, Xingcun; Gao, Hongliang; Lu, Qian

Year: 2023

Venue: Experimental and therapeutic medicine

DOI: https://doi.org/10.3892/etm.2023.12237

Paper Dysregulated mTOR signaling in Alzheimer's disease: Linking pathogenic mechanisms to emerging therapeutic strategies.

Zhang, Siqi; Wang, Tianyi; Xue, Guocheng et al. · 2026 · Journal of Alzheimer's disease : JAD · DOI

Full title: Dysregulated mTOR signaling in Alzheimer's disease: Linking pathogenic mechanisms to emerging therapeutic strategies.

Authors: Zhang, Siqi; Wang, Tianyi; Xue, Guocheng; Zheng, Ruwen; Ding, Ning; Yang, Jing; Zhang, Miao

Year: 2026

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.1177/13872877251400667

Paper Current and Future Treatments in Alzheimer Disease: An Update

Yiannopoulou, Konstantina G.; Papageorgiou, Sokratis G. · 2020 · Journal of Central Nervous System Disease · DOI

Full title: Current and Future Treatments in Alzheimer Disease: An Update

Authors: Yiannopoulou, Konstantina G.; Papageorgiou, Sokratis G.

Year: 2020

Venue: Journal of Central Nervous System Disease

DOI: https://doi.org/10.1177/1179573520907397

Paper Obestatin attenuated methamphetamine-induced PC12 cells neurotoxicity via inhibiting autophagy and apoptosis.

Foroughi, K; Jahanbani, S; Khaksari, M et al. · 2020 · Human & experimental toxicology · DOI

Full title: Obestatin attenuated methamphetamine-induced PC12 cells neurotoxicity via inhibiting autophagy and apoptosis.

Authors: Foroughi, K; Jahanbani, S; Khaksari, M; Shayannia, A

Year: 2020

Venue: Human & experimental toxicology

DOI: https://doi.org/10.1177/0960327119886036

Paper Mechanisms of development of multimorbidity in the elderly

Barnes, Peter J. · 2015 · European Respiratory Journal · DOI

Full title: Mechanisms of development of multimorbidity in the elderly

Authors: Barnes, Peter J.

Year: 2015

Venue: European Respiratory Journal

DOI: https://doi.org/10.1183/09031936.00229714

Paper Enhancing Lysosomal Activation Restores Neural Stem Cell Function During Aging.

Audesse, Amanda J; Webb, Ashley E · 2018 · Journal of experimental neuroscience · DOI

Full title: Enhancing Lysosomal Activation Restores Neural Stem Cell Function During Aging.

Authors: Audesse, Amanda J; Webb, Ashley E

Year: 2018

Venue: Journal of experimental neuroscience

DOI: https://doi.org/10.1177/1179069518795874

Paper Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors

Lechner, Katharina; Schacky, Clemens von; McKenzie, Amy L. et al. · 2019 · European Journal of Preventive Cardiology · DOI

Full title: Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors

Authors: Lechner, Katharina; Schacky, Clemens von; McKenzie, Amy L.; Worm, Nicolai; Nixdorff, Uwe; Lechner, Benjamin; Kränkel, Nicolle; Halle, Martin; Krauss, Ronald M.; Scherr, Johannes

Year: 2019

Venue: European Journal of Preventive Cardiology

DOI: https://doi.org/10.1177/2047487319869400

Paper Loss of Autophagy Causes Increased Apoptosis of Tibial Plateau Chondrocytes in Guinea Pigs with Spontaneous Osteoarthritis.

Wang, Xiao-Jian; Tian, Wei; Xu, Wei-Wei et al. · 2021 · Cartilage · DOI

Full title: Loss of Autophagy Causes Increased Apoptosis of Tibial Plateau Chondrocytes in Guinea Pigs with Spontaneous Osteoarthritis.

Authors: Wang, Xiao-Jian; Tian, Wei; Xu, Wei-Wei; Lu, Xiao; Zhang, Yu-Ming; Li, Li-Jun; Chang, Feng

Year: 2021

Venue: Cartilage

DOI: https://doi.org/10.1177/19476035211044820

Paper Microglia TFEB activation attenuates Alzheimer's disease pathology by enhancing autophagy-lysosomal function.

Kim, Yeji; Ha, Tae-Young; Kondaurova, Oksana et al. · 2026 · Journal of neuroinflammation · DOI

Full title: Microglia TFEB activation attenuates Alzheimer's disease pathology by enhancing autophagy-lysosomal function.

Authors: Kim, Yeji; Ha, Tae-Young; Kondaurova, Oksana; Lee, Myung-Shik; Chang, Keun-A

Year: 2026

Venue: Journal of neuroinflammation

DOI: https://doi.org/10.1186/s12974-026-03728-z

Paper The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synuclein: Potential role of AMPK-JNK pathway.

Amireddy, Niharika; Dulam, Vandana; Kaul, Shweta et al. · 2023 · Cellular signalling · DOI

Full title: The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synuclein: Potential role of AMPK-JNK pathway.

Authors: Amireddy, Niharika; Dulam, Vandana; Kaul, Shweta; Pakkiri, Rajeswari; Kalivendi, Shasi V

Year: 2023

Venue: Cellular signalling

DOI: https://doi.org/10.1016/j.cellsig.2023.110769

Paper Sorting out the trash: the spatial nature of eukaryotic protein quality control.

Sontag, Emily Mitchell; Vonk, Willianne I M; Frydman, Judith · 2014 · Current opinion in cell biology · DOI

Full title: Sorting out the trash: the spatial nature of eukaryotic protein quality control.

Authors: Sontag, Emily Mitchell; Vonk, Willianne I M; Frydman, Judith

Year: 2014

Venue: Current opinion in cell biology

DOI: https://doi.org/10.1016/j.ceb.2013.12.006

Paper Melatonin modulates autophagy, mitochondria and antioxidant in the liver and brain of Perccottus glenni during recovery from freezing.

Ye, Cunrun; Ning, Zhaoyang; Hu, Tingting et al. · 2025 · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · DOI

Full title: Melatonin modulates autophagy, mitochondria and antioxidant in the liver and brain of Perccottus glenni during recovery from freezing.

Authors: Ye, Cunrun; Ning, Zhaoyang; Hu, Tingting; Zhao, Xiaoyu; Mu, Weijie

Year: 2025

Venue: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

DOI: https://doi.org/10.1016/j.cbpa.2025.111824

Paper microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.

Chen, Xin; Cao, Yanhong; Guo, Yining et al. · 2024 · Cellular signalling · DOI

Full title: microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.

Authors: Chen, Xin; Cao, Yanhong; Guo, Yining; Liu, Jing; Ye, Xiaohan; Li, Huan; Zhang, Lu; Feng, Wenwei; Xian, Shaoxiang; Yang, Zhongqi; Wang, Lingjun; Wang, Ting

Year: 2024

Venue: Cellular signalling

DOI: https://doi.org/10.1016/j.cellsig.2024.111136

Paper VMP1 enhances autophagy to mitigate cardiac fibroblast activation and reduce post-ischemia-reperfusion fibrosis.

Li, Ya; Feng, Cuina; Zu, Yugang et al. · 2025 · Cellular signalling · DOI

Full title: VMP1 enhances autophagy to mitigate cardiac fibroblast activation and reduce post-ischemia-reperfusion fibrosis.

Authors: Li, Ya; Feng, Cuina; Zu, Yugang; Long, Pan; Chen, Aijun

Year: 2025

Venue: Cellular signalling

DOI: https://doi.org/10.1016/j.cellsig.2025.112105

Paper HGF protected against diabetic nephropathy via autophagy-lysosome pathway in podocyte by modulating PI3K/Akt-GSK3β-TFEB axis.

Hou, Bo; Li, Yankun; Li, Xue et al. · 2020 · Cellular signalling · DOI

Full title: HGF protected against diabetic nephropathy via autophagy-lysosome pathway in podocyte by modulating PI3K/Akt-GSK3β-TFEB axis.

Authors: Hou, Bo; Li, Yankun; Li, Xue; Zhang, Congying; Zhao, Zhonghua; Chen, Qi; Zhang, Nong; Li, Hui

Year: 2020

Venue: Cellular signalling

DOI: https://doi.org/10.1016/j.cellsig.2020.109744

Paper Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells.

Katiyar, Parul; Banerjee, Somesh; Nathani, Sandip et al. · 2022 · Current research in toxicology · DOI

Full title: Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells.

Authors: Katiyar, Parul; Banerjee, Somesh; Nathani, Sandip; Roy, Partha

Year: 2022

Venue: Current research in toxicology

DOI: https://doi.org/10.1016/j.crtox.2022.100072

Paper Bisphenol A increases TLR4-mediated inflammatory response by up-regulation of autophagy-related protein in lung of adolescent mice.

Wang, Simeng; Yang, Yilong; Luo, Dan et al. · 2021 · Chemosphere · DOI

Full title: Bisphenol A increases TLR4-mediated inflammatory response by up-regulation of autophagy-related protein in lung of adolescent mice.

Authors: Wang, Simeng; Yang, Yilong; Luo, Dan; Zhai, Lingling; Bai, Yinglong; Wei, Wei; Sun, Qi; Jia, Lihong

Year: 2021

Venue: Chemosphere

DOI: https://doi.org/10.1016/j.chemosphere.2020.128837

Paper Effect of trehalose on mortality and disease severity in ICU-admitted patients: Protocol for a triple-blind, randomized, placebo-controlled clinical trial.

Sahranavard, Mehrdad; Hosseinjani, Hesamoddin; Emadzadeh, Maryam et al. · 2024 · Contemporary clinical trials communications · DOI

Full title: Effect of trehalose on mortality and disease severity in ICU-admitted patients: Protocol for a triple-blind, randomized, placebo-controlled clinical trial.

Authors: Sahranavard, Mehrdad; Hosseinjani, Hesamoddin; Emadzadeh, Maryam; Jamialahmadi, Tannaz; Sahebkar, Amirhossein

Year: 2024

Venue: Contemporary clinical trials communications

DOI: https://doi.org/10.1016/j.conctc.2024.101324

Paper Galangin alleviated myocardial ischemia-reperfusion injury by enhancing autophagic flux and inhibiting inflammation.

Zhang, Jian; Hu, Shiyu; Gao, Yang et al. · 2023 · European journal of pharmacology · DOI

Full title: Galangin alleviated myocardial ischemia-reperfusion injury by enhancing autophagic flux and inhibiting inflammation.

Authors: Zhang, Jian; Hu, Shiyu; Gao, Yang; Wei, Xiang; Qu, Yanan; Gao, Rifeng; Lv, Yang; Wang, Jingpu; Wang, Yiwen; Yang, Ji'e; Cao, Jiatian; Zhang, Feng; Ge, Junbo

Year: 2023

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2023.175621

Paper Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli.

Wang, Xiaodan; Gao, Lihui; Lin, Hua et al. · 2018 · European journal of pharmacology · DOI

Full title: Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli.

Authors: Wang, Xiaodan; Gao, Lihui; Lin, Hua; Song, Jingling; Wang, Jinwen; Yin, Yumin; Zhao, Jianghu; Xu, Xiangwei; Li, Zhenkun; Li, Ling

Year: 2018

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2018.02.009

Paper Pioglitazone protects tubular cells against hypoxia/reoxygenation injury through enhancing autophagy via AMPK-mTOR signaling pathway.

Xi, Xiaoqing; Zou, Cong; Ye, Zhenfeng et al. · 2019 · European journal of pharmacology · DOI

Full title: Pioglitazone protects tubular cells against hypoxia/reoxygenation injury through enhancing autophagy via AMPK-mTOR signaling pathway.

Authors: Xi, Xiaoqing; Zou, Cong; Ye, Zhenfeng; Huang, Yawei; Chen, Tongchang; Hu, Honglin

Year: 2019

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2019.172695

Paper Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.

Jiang, Shuai; Ma, Feixia; Lou, Junsheng et al. · 2024 · European journal of pharmacology · DOI

Full title: Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.

Authors: Jiang, Shuai; Ma, Feixia; Lou, Junsheng; Li, Jiafeng; Shang, Xiushuai; Li, Yifan; Wu, Junsong; Xu, Sanzhong

Year: 2024

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2024.176455

Paper Novel prospects in targeting neurodegenerative disorders via autophagy.

Khan, Shumayila; Upadhyay, Saurabh; Hassan, Md Imtaiyaz · 2024 · European journal of pharmacology · DOI

Full title: Novel prospects in targeting neurodegenerative disorders via autophagy.

Authors: Khan, Shumayila; Upadhyay, Saurabh; Hassan, Md Imtaiyaz

Year: 2024

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2024.177060

Paper Metformin attenuates diabetes-induced tau hyperphosphorylation in vitro and in vivo by enhancing autophagic clearance.

Chen, Jin-Liang; Luo, Cheng; Pu, Die et al. · 2019 · Experimental neurology · DOI

Full title: Metformin attenuates diabetes-induced tau hyperphosphorylation in vitro and in vivo by enhancing autophagic clearance.

Authors: Chen, Jin-Liang; Luo, Cheng; Pu, Die; Zhang, Guo-Qiang; Zhao, Yu-Xing; Sun, Yue; Zhao, Ke-Xiang; Liao, Zhi-Yin; Lv, An-Kang; Zhu, Shi-Yu; Zhou, Jing; Xiao, Qian

Year: 2019

Venue: Experimental neurology

DOI: https://doi.org/10.1016/j.expneurol.2018.09.008

Paper Restoring autophagy flux by rolipram attenuates ototoxicity in Hearing loss.

Vijayakumar, Karthikeyan A; Jang, Chul Ho; Cho, Gwang-Won · 2026 · European journal of pharmacology · DOI

Full title: Restoring autophagy flux by rolipram attenuates ototoxicity in Hearing loss.

Authors: Vijayakumar, Karthikeyan A; Jang, Chul Ho; Cho, Gwang-Won

Year: 2026

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2025.178473

Paper Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway.

Huang, Hefei; Wang, Tianlun; Wang, Luopei et al. · 2023 · Experimental gerontology · DOI

Full title: Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway.

Authors: Huang, Hefei; Wang, Tianlun; Wang, Luopei; Huang, Yan; Li, Weili; Wang, Jin'e; Hu, Yuanlang; Zhou, Zhiyong

Year: 2023

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2023.112305

Paper First evidence of the protective role of melatonin in counteracting cadmium toxicity in the rat ovary via the mTOR pathway.

Kechiche, Safa; Venditti, Massimo; Knani, Latifa et al. · 2021 · Environmental pollution (Barking, Essex : 1987) · DOI

Full title: First evidence of the protective role of melatonin in counteracting cadmium toxicity in the rat ovary via the mTOR pathway.

Authors: Kechiche, Safa; Venditti, Massimo; Knani, Latifa; Jabłońska, Karolina; Dzięgiel, Piotr; Messaoudi, Imed; Reiter, Russel J; Minucci, Sergio

Year: 2021

Venue: Environmental pollution (Barking, Essex : 1987)

DOI: https://doi.org/10.1016/j.envpol.2020.116056

Paper Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats.

Zhou, Keren; Enkhjargal, Budbazar; Mo, Jun et al. · 2021 · Experimental neurology · DOI

Full title: Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats.

Authors: Zhou, Keren; Enkhjargal, Budbazar; Mo, Jun; Zhang, Tongyu; Zhu, Qiquan; Wu, Pei; Reis, Cesar; Tang, Jiping; Zhang, John H; Zhang, Jianmin

Year: 2021

Venue: Experimental neurology

DOI: https://doi.org/10.1016/j.expneurol.2021.113752

Paper SIRT1 suppresses cellular senescence and inflammatory cytokine release in human dermal fibroblasts by promoting the deacetylation of NF-κB and activating autophagy.

Sung, Jin Young; Kim, Seul Gi; Kim, Jae-Ryong et al. · 2021 · Experimental gerontology · DOI

Full title: SIRT1 suppresses cellular senescence and inflammatory cytokine release in human dermal fibroblasts by promoting the deacetylation of NF-κB and activating autophagy.

Authors: Sung, Jin Young; Kim, Seul Gi; Kim, Jae-Ryong; Choi, Hyoung Chul

Year: 2021

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2021.111394

Paper Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat.

Chen, Yayu; Wei, Gen; Feng, Xiaojin et al. · 2024 · Experimental neurology · DOI

Full title: Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat.

Authors: Chen, Yayu; Wei, Gen; Feng, Xiaojin; Lei, Enjun; Zhang, Lieliang

Year: 2024

Venue: Experimental neurology

DOI: https://doi.org/10.1016/j.expneurol.2024.114842

Paper Pramipexole improves cognitive deficits and synaptic plasticity impairments in 3xTg-AD mice through enhancing autophagy.

Tuo, Chunmei; Sui, Xiaofan; Cui, Chenglong et al. · 2025 · Experimental neurology · DOI

Full title: Pramipexole improves cognitive deficits and synaptic plasticity impairments in 3xTg-AD mice through enhancing autophagy.

Authors: Tuo, Chunmei; Sui, Xiaofan; Cui, Chenglong; Han, Feifei; Jiao, Juanjuan; Cai, Hongyan; Wu, Meina

Year: 2025

Venue: Experimental neurology

DOI: https://doi.org/10.1016/j.expneurol.2025.115503

Paper Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy.

Li, Zhen-Yu; Chen, Li-Hua; Zhao, Xiu-Yun et al. · 2021 · Experimental neurology · DOI

Full title: Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy.

Authors: Li, Zhen-Yu; Chen, Li-Hua; Zhao, Xiu-Yun; Chen, Hong; Sun, Yan-Yun; Lu, Mei-Hong; Wang, Zhao-Tao; Chen, Mei; Lu, Li; Huang, Wenhui; Chen, Rui; Xu, De-En; Xu, Ru-Xiang; Ma, Quan-Hong

Year: 2021

Venue: Experimental neurology

DOI: https://doi.org/10.1016/j.expneurol.2021.113742

Paper Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.

Zhong, Yujie; Luo, Ruilin; Liu, Qi et al. · 2022 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · DOI

Full title: Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.

Authors: Zhong, Yujie; Luo, Ruilin; Liu, Qi; Zhu, Jiachang; Lei, Min; Liang, Xiaofei; Wang, Xin; Peng, Xiaoli

Year: 2022

Venue: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

DOI: https://doi.org/10.1016/j.fct.2021.112697

Paper Impaired autophagy contributes to hepatocellular damage during ischemia/reperfusion: heme oxygenase-1 as a possible regulator.

Yun, Nari; Cho, Hong-Ik; Lee, Sun-Mee · 2014 · Free radical biology & medicine · DOI

Full title: Impaired autophagy contributes to hepatocellular damage during ischemia/reperfusion: heme oxygenase-1 as a possible regulator.

Authors: Yun, Nari; Cho, Hong-Ik; Lee, Sun-Mee

Year: 2014

Venue: Free radical biology & medicine

DOI: https://doi.org/10.1016/j.freeradbiomed.2013.12.014

Paper Targeting LKB1-AMPK-SIRT1-induced autophagy and mitophagy pathways improves cerebrovascular homeostasis in APP/PS1 mice.

Li, Yawen; Wang, Tongxing; Li, Hongrong et al. · 2025 · Free radical biology & medicine · DOI

Full title: Targeting LKB1-AMPK-SIRT1-induced autophagy and mitophagy pathways improves cerebrovascular homeostasis in APP/PS1 mice.

Authors: Li, Yawen; Wang, Tongxing; Li, Hongrong; Jiang, Yuning; Shen, Xiaogang; Kang, Ning; Guo, Zhifang; Zhang, Runtao; Lu, Xuan; Kang, Tianyu; Li, Mengnan; Hou, Yunlong; Wu, Yiling

Year: 2025

Venue: Free radical biology & medicine

DOI: https://doi.org/10.1016/j.freeradbiomed.2025.03.045

Paper Cladrin alleviates dexamethasone-induced apoptosis of osteoblasts and promotes bone formation through autophagy induction via AMPK/mTOR signaling.

Rai, Reena; Singh, Krishna Bhan; Khanka, Sonu et al. · 2022 · Free radical biology & medicine · DOI

Full title: Cladrin alleviates dexamethasone-induced apoptosis of osteoblasts and promotes bone formation through autophagy induction via AMPK/mTOR signaling.

Authors: Rai, Reena; Singh, Krishna Bhan; Khanka, Sonu; Maurya, Rakesh; Singh, Divya

Year: 2022

Venue: Free radical biology & medicine

DOI: https://doi.org/10.1016/j.freeradbiomed.2022.08.028

Paper Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.

Li, Ningning; Sun, Shan; Ma, Guoqiang et al. · 2022 · Fundamental research · DOI

Full title: Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.

Authors: Li, Ningning; Sun, Shan; Ma, Guoqiang; Hou, Hongyu; Ma, Qilian; Zhang, Li; Zhang, Zengli; Wang, Hongfeng; Ying, Zheng

Year: 2022

Venue: Fundamental research

DOI: https://doi.org/10.1016/j.fmre.2021.12.017

Paper Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.

Zhu, Min; Zhang, Yunshan; Pan, Jun et al. · 2022 · Fish & shellfish immunology · DOI

Full title: Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.

Authors: Zhu, Min; Zhang, Yunshan; Pan, Jun; Tong, Xinyu; Zhang, Xing; Hu, Xiaolong; Gong, Chengliang

Year: 2022

Venue: Fish & shellfish immunology

DOI: https://doi.org/10.1016/j.fsi.2022.07.069

Paper KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.

Tang, Zhanbin; Cao, Jingwei; Yao, Jialin et al. · 2023 · Free radical biology & medicine · DOI

Full title: KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.

Authors: Tang, Zhanbin; Cao, Jingwei; Yao, Jialin; Fan, Xuehui; Zhao, Jingkun; Zhao, Mianqiao; Duan, Qiong; Han, Baichao; Duan, Shurong

Year: 2023

Venue: Free radical biology & medicine

DOI: https://doi.org/10.1016/j.freeradbiomed.2022.12.099

Paper Mito-Tempo suppresses autophagic flux via the PI3K/Akt/mTOR signaling pathway in neuroblastoma SH-SY5Y cells.

Mukem, Sirirak; Thongbuakaew, Tipsuda; Khornchatri, Kanjana · 2021 · Heliyon · DOI

Full title: Mito-Tempo suppresses autophagic flux via the PI3K/Akt/mTOR signaling pathway in neuroblastoma SH-SY5Y cells.

Authors: Mukem, Sirirak; Thongbuakaew, Tipsuda; Khornchatri, Kanjana

Year: 2021

Venue: Heliyon

DOI: https://doi.org/10.1016/j.heliyon.2021.e07310

Paper Quercetin attenuated ropivacaine-induced neurotoxicity in SH-SY5Y cells through upregulating Pim1 and enhancing autophagy.

Liu, Yinghai; Ren, Ling; Sun, Yangyang et al. · 2024 · Heliyon · DOI

Full title: Quercetin attenuated ropivacaine-induced neurotoxicity in SH-SY5Y cells through upregulating Pim1 and enhancing autophagy.

Authors: Liu, Yinghai; Ren, Ling; Sun, Yangyang; Yan, Jing; Gong, Gu

Year: 2024

Venue: Heliyon

DOI: https://doi.org/10.1016/j.heliyon.2024.e33829

Paper Host immunity and intracellular bacteria evasion mechanisms: Enhancing host-directed therapies with drug delivery systems.

Cai, Jiayang; Zhou, Han; Liu, Mingwei et al. · 2025 · International journal of antimicrobial agents · DOI

Full title: Host immunity and intracellular bacteria evasion mechanisms: Enhancing host-directed therapies with drug delivery systems.

Authors: Cai, Jiayang; Zhou, Han; Liu, Mingwei; Zhang, Dingjian; Lv, Jingxuan; Xue, Haokun; Zhou, Houcheng; Zhang, Wenli

Year: 2025

Venue: International journal of antimicrobial agents

DOI: https://doi.org/10.1016/j.ijantimicag.2025.107492

Paper Orchestrating AMPK/mTOR signaling to initiate melittin-induced mitophagy: A neuroprotective strategy against Parkinson's disease.

Chen, Mingran; Wang, Xue; Bao, Shuangyan et al. · 2024 · International journal of biological macromolecules · DOI

Full title: Orchestrating AMPK/mTOR signaling to initiate melittin-induced mitophagy: A neuroprotective strategy against Parkinson's disease.

Authors: Chen, Mingran; Wang, Xue; Bao, Shuangyan; Wang, Dexiao; Zhao, Jie; Wang, Qian; Liu, Chaojie; Zhao, Haiong; Zhang, Chenggui

Year: 2024

Venue: International journal of biological macromolecules

DOI: https://doi.org/10.1016/j.ijbiomac.2024.136119

Paper Progesterone suppresses Aβ42-induced neuroinflammation by enhancing autophagy in astrocytes.

Hong, Yang; Liu, Yunjiang; Zhang, Geng et al. · 2018 · International immunopharmacology · DOI

Full title: Progesterone suppresses Aβ42-induced neuroinflammation by enhancing autophagy in astrocytes.

Authors: Hong, Yang; Liu, Yunjiang; Zhang, Geng; Wu, Honghai; Hou, Yanning

Year: 2018

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2017.11.044

Paper Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.

Huang, Zhenzhen; Pan, Lei; Xiao, Zilong et al. · 2025 · International journal of cardiology · DOI

Full title: Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.

Authors: Huang, Zhenzhen; Pan, Lei; Xiao, Zilong; Rao, Fang; Yakupu, Wusiman; Rouzi, Abudunaizier; Cheng, Kuan; Pang, Yang; Su, Yangang; Wu, Di

Year: 2025

Venue: International journal of cardiology

DOI: https://doi.org/10.1016/j.ijcard.2025.133681

Paper Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer’s Disease

Panza, Francesco; Solfrizzi, Vincenzo; Seripa, Davide et al. · 2016 · BioMed Research International · DOI

Full title: Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer’s Disease

Authors: Panza, Francesco; Solfrizzi, Vincenzo; Seripa, Davide; Imbimbo, Bruno P.; Lozupone, Madia; Santamato, Andrea; Zecca, Chiara; Barulli, Maria Rosaria; Bellomo, Antonello; Pilotto, Alberto; Daniele, Antonio; Greco, Antonio; Logroscino, Giancarlo

Year: 2016

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2016/3245935

Paper Role of ROS and RNS Sources in Physiological and Pathological Conditions

Meo, S. Di; Reed, Tanea T.; Venditti, Paola et al. · 2016 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Role of ROS and RNS Sources in Physiological and Pathological Conditions

Authors: Meo, S. Di; Reed, Tanea T.; Venditti, Paola; Víctor, Víctor M.

Year: 2016

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2016/1245049

Paper The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

Manoharan, Shanmugam; Guillemin, Gilles J.; Abiramasundari, Rajagopal Selladurai et al. · 2016 · Oxidative Medicine and Cellular Longevity · DOI

Full title: The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

Authors: Manoharan, Shanmugam; Guillemin, Gilles J.; Abiramasundari, Rajagopal Selladurai; Essa, Musthafa Mohamed; Akbar, Mohammed; Akbar, Mohammed

Year: 2016

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2016/8590578

Paper Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy

Duan, Xiao‐Chun; Wen, Zunjia; Shen, Haitao et al. · 2016 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy

Authors: Duan, Xiao‐Chun; Wen, Zunjia; Shen, Haitao; Shen, Meifen; Chen, Gang

Year: 2016

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2016/1203285

Paper Tumor Suppression and Promotion by Autophagy

Ávalos, Yenniffer; Canales, Jimena; Bravo, Roberto et al. · 2014 · BioMed Research International · DOI

Full title: Tumor Suppression and Promotion by Autophagy

Authors: Ávalos, Yenniffer; Canales, Jimena; Bravo, Roberto; Criollo, Alfredo; Lavandero, Sergio; Quest, Andrew F. G.

Year: 2014

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2014/603980

Paper Multifaceted Roles of GSK‐3 in Cancer and Autophagy‐Related Diseases

Mancinelli, Romina; Carpino, Guido; Petrungaro, Simonetta et al. · 2017 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Multifaceted Roles of GSK‐3 in Cancer and Autophagy‐Related Diseases

Authors: Mancinelli, Romina; Carpino, Guido; Petrungaro, Simonetta; Mammola, Caterina Loredana; Tomaipitinca, Luana; Filippini, Antonio; Facchiano, Antonio; Ziparo, Elio; Giampietri, Claudia

Year: 2017

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2017/4629495

Paper A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling

Schirone, Leonardo; Forte, Maurizio; Palmerio, Silvia et al. · 2017 · Oxidative Medicine and Cellular Longevity · DOI

Full title: A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling

Authors: Schirone, Leonardo; Forte, Maurizio; Palmerio, Silvia; Yee, Derek; Nocella, Cristina; Angelini, Francesco; Pagano, Francesca; Schiavon, Sonia; Bordin, Antonella; Carrizzo, Albino; Vecchione, Carmine; Valenti, Valentina; Chimenti, Isotta; Falco, Elena De; Sciarretta, Sebastiano; Frati, Giacomo

Year: 2017

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2017/3920195

Paper Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders

Zhou, Keren; Shi, Ligen; Wang, Yan et al. · 2016 · Journal of Immunology Research · DOI

Full title: Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders

Authors: Zhou, Keren; Shi, Ligen; Wang, Yan; Chen, Sheng; Zhang, Jianmin

Year: 2016

Venue: Journal of Immunology Research

DOI: https://doi.org/10.1155/2016/9238290

Paper Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders

Enogieru, Adaze Bijou; Haylett, William; Hiss, Donavon Charles et al. · 2018 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders

Authors: Enogieru, Adaze Bijou; Haylett, William; Hiss, Donavon Charles; Bardien, Soraya; Ekpo, Okobi E.

Year: 2018

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2018/6241017

Paper The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy

Sifuentes-Franco, Sonia; Pacheco-Moisés, Fermín Paúl; Rodríguez-Carrizález, Adolfo Daniel et al. · 2017 · Journal of Diabetes Research · DOI

Full title: The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy

Authors: Sifuentes-Franco, Sonia; Pacheco-Moisés, Fermín Paúl; Rodríguez-Carrizález, Adolfo Daniel; Miranda‐Díaz, Alejandra Guillermina

Year: 2017

Venue: Journal of Diabetes Research

DOI: https://doi.org/10.1155/2017/1673081

Paper Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer

Pellati, Federica; Borgonetti, Vittoria; Brighenti, Virginia et al. · 2018 · BioMed Research International · DOI

Full title: Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer

Authors: Pellati, Federica; Borgonetti, Vittoria; Brighenti, Virginia; Biagi, Marco; Benvenuti, Stefania; Corsi, Lorenzo

Year: 2018

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2018/1691428

Paper Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

Folch, Jaume; Petrov, Dmitry S.; Ettcheto, Miren et al. · 2016 · Neural Plasticity · DOI

Full title: Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

Authors: Folch, Jaume; Petrov, Dmitry S.; Ettcheto, Miren; Abad, Sònia; Sánchez‐López, Elena; García, María L.; Olloquequi, Jordi; Beas‐Zárate, Carlos; Auladell, Carme; Camins, Antoni

Year: 2016

Venue: Neural Plasticity

DOI: https://doi.org/10.1155/2016/8501693

Paper Oxidant/Antioxidant Imbalance in Alzheimer’s Disease: Therapeutic and Diagnostic Prospects

Wojsiat, Joanna; Zoltowska, Katarzyna Marta; Laskowska-Kaszub, Katarzyna et al. · 2018 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Oxidant/Antioxidant Imbalance in Alzheimer’s Disease: Therapeutic and Diagnostic Prospects

Authors: Wojsiat, Joanna; Zoltowska, Katarzyna Marta; Laskowska-Kaszub, Katarzyna; Wojda, Urszula

Year: 2018

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2018/6435861

Paper Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy

Marinković, Mija; Šprung, Matilda; Buljubašić, Maja et al. · 2018 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy

Authors: Marinković, Mija; Šprung, Matilda; Buljubašić, Maja; Novak, Ivana

Year: 2018

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2018/8023821

Paper Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1

Gomes, Bruno Alexandre Quadros; Silva, João Paulo Bastos; Romeiro, Camila Fernanda Rodrigues et al. · 2018 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1

Authors: Gomes, Bruno Alexandre Quadros; Silva, João Paulo Bastos; Romeiro, Camila Fernanda Rodrigues; Santos, Sávio Monteiro dos; Rodrigues, Caroline Azulay; Gonçalves, Pricila Rodrigues; Sakai, Joni Tetsuo; Mendes, Paulo Fernando Santos; Varela, Everton Luiz Pompeu; Monteiro, Marta Chagas

Year: 2018

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2018/8152373

Paper Electroacupuncture Preconditioning Improves Myocardial Infarction Injury via Enhancing AMPK-Dependent Autophagy in Rats.

Zeng, Qing; He, He; Wang, Xian-Bao et al. · 2018 · BioMed research international · DOI

Full title: Electroacupuncture Preconditioning Improves Myocardial Infarction Injury via Enhancing AMPK-Dependent Autophagy in Rats.

Authors: Zeng, Qing; He, He; Wang, Xian-Bao; Zhou, Yu-Qing; Lin, Hong-Xin; Tan, Zhi-Peng; He, Shang-Fei; Huang, Guo-Zhi

Year: 2018

Venue: BioMed research international

DOI: https://doi.org/10.1155/2018/1238175

Paper Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

Roca‐Agujetas, Vicente; Dios, Cristina de; Pinilla, Laura Lestón et al. · 2019 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

Authors: Roca‐Agujetas, Vicente; Dios, Cristina de; Pinilla, Laura Lestón; Marı́, Montserrat; Morales, Albert; Colell, Anna

Year: 2019

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2019/3809308

Paper The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis

Huang, Michael; Chiang, Shannon; Kalinowski, Danuta S. et al. · 2019 · Oxidative Medicine and Cellular Longevity · DOI

Full title: The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis

Authors: Huang, Michael; Chiang, Shannon; Kalinowski, Danuta S.; Bae, Dong-Hun; Sahni, Sumit; Richardson, Des R.

Year: 2019

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2019/6392763

Paper Oxidative Stress-Mediated Blood-Brain Barrier (BBB) Disruption in Neurological Diseases

Song, Ke; Li, Yuanyuan; Zhang, Hanlai et al. · 2020 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Oxidative Stress-Mediated Blood-Brain Barrier (BBB) Disruption in Neurological Diseases

Authors: Song, Ke; Li, Yuanyuan; Zhang, Hanlai; An, Na; Wei, Yufei; Wang, Liqin; Tian, Chao; Yuan, Mengchen; Sun, Yikun; Xing, Yanwei; Gao, Yonghong

Year: 2020

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2020/4356386

Paper Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases

Forni, Cinzia; Facchiano, Francesco; Bartoli, Manuela et al. · 2019 · BioMed Research International · DOI

Full title: Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases

Authors: Forni, Cinzia; Facchiano, Francesco; Bartoli, Manuela; Pieretti, Stefano; Facchiano, Antonio; D’Arcangelo, Daniela; Norelli, Sandro; Valle, G Mata-Torres; Nisini, Roberto; Beninati, Simone; Tabolacci, Claudio; Jadeja, Ravirajsinh N.

Year: 2019

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2019/8748253

Paper Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity.

Shi, Yimin; Gao, Yanbin; Wang, Tao et al. · 2020 · Evidence-based complementary and alternative medicine : eCAM · DOI

Full title: Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity.

Authors: Shi, Yimin; Gao, Yanbin; Wang, Tao; Wang, Xiaolei; He, Jiaxin; Xu, Jiayi; Wu, Bingjie; Li, Yimeng

Year: 2020

Venue: Evidence-based complementary and alternative medicine : eCAM

DOI: https://doi.org/10.1155/2020/1903627

Paper Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.

Zhao, Xia; Liu, Linlin; Jiang, Yizhou et al. · 2020 · Oxidative medicine and cellular longevity · DOI

Full title: Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.

Authors: Zhao, Xia; Liu, Linlin; Jiang, Yizhou; Silva, Marta; Zhen, Xuechu; Zheng, Wenhua

Year: 2020

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2020/2524174

Paper Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.

Zhu, Xuwei; Hu, Xinli; Lou, Junsheng et al. · 2021 · Oxidative medicine and cellular longevity · DOI

Full title: Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.

Authors: Zhu, Xuwei; Hu, Xinli; Lou, Junsheng; Li, Jiafeng; Xu, Yu; Yu, Gaoxiang; Wu, Chenyu; Ding, Jian; Gao, Weiyang; Xiao, Jian; Zhou, Kailiang; Jia, Chang

Year: 2021

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2021/6610603

Paper Autophagy in Age-Related Macular Degeneration: A Regulatory Mechanism of Oxidative Stress.

Zhang, Zi-Yuan; Bao, Xiao-Li; Cong, Yun-Yi et al. · 2020 · Oxidative medicine and cellular longevity · DOI

Full title: Autophagy in Age-Related Macular Degeneration: A Regulatory Mechanism of Oxidative Stress.

Authors: Zhang, Zi-Yuan; Bao, Xiao-Li; Cong, Yun-Yi; Fan, Bin; Li, Guang-Yu

Year: 2020

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2020/2896036

Paper Mesenchymal Stem Cells Attenuate Diabetic Lung Fibrosis via Adjusting Sirt3-Mediated Stress Responses in Rats.

Chen, Yang; Zhang, Fuping; Wang, Di et al. · 2020 · Oxidative medicine and cellular longevity · DOI

Full title: Mesenchymal Stem Cells Attenuate Diabetic Lung Fibrosis via Adjusting Sirt3-Mediated Stress Responses in Rats.

Authors: Chen, Yang; Zhang, Fuping; Wang, Di; Li, Lan; Si, Haibo; Wang, Chengshi; Liu, Jingping; Chen, Younan; Cheng, Jingqiu; Lu, Yanrong

Year: 2020

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2020/8076105

Paper Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response.

Zhuo, Luo; Chen, Xiaobing; Sun, Yan et al. · 2020 · BioMed research international · DOI

Full title: Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response.

Authors: Zhuo, Luo; Chen, Xiaobing; Sun, Yan; Wang, Yanli; Shi, Yuanfeng; Bu, Lin; Xia, Wei; Han, Jiayan; Chen, Dongmei; Li, Xiaomin

Year: 2020

Venue: BioMed research international

DOI: https://doi.org/10.1155/2020/5960375

Paper Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.

Cheng, Yufei; Pan, Xudong; Wang, Jing et al. · 2020 · Oxidative medicine and cellular longevity · DOI

Full title: Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.

Authors: Cheng, Yufei; Pan, Xudong; Wang, Jing; Li, Xu; Yang, Shaonan; Yin, Ruihua; Ma, Aijun; Zhu, Xiaoyan

Year: 2020

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2020/3186306

Paper Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

Robledinos-Antón, Natalia; Fernández-Ginés, Raquel; Manda, Gina et al. · 2019 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

Authors: Robledinos-Antón, Natalia; Fernández-Ginés, Raquel; Manda, Gina; Cuadrado, Antonio

Year: 2019

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2019/9372182

Paper Ginkgolide B Protects Cardiomyocytes from Angiotensin II-Induced Hypertrophy via Regulation of Autophagy through SIRT1-FoxO1.

Jiang, Qingyuan; Lu, Ming; Li, Jinyu et al. · 2021 · Cardiovascular therapeutics · DOI

Full title: Ginkgolide B Protects Cardiomyocytes from Angiotensin II-Induced Hypertrophy via Regulation of Autophagy through SIRT1-FoxO1.

Authors: Jiang, Qingyuan; Lu, Ming; Li, Jinyu; Zhu, Zhongsheng

Year: 2021

Venue: Cardiovascular therapeutics

DOI: https://doi.org/10.1155/2021/5554569

Paper Targeting Mitochondrial Biogenesis with Polyphenol Compounds

Chodari, Leila; Aytemir, Mutlu Dilsiz; Vahedi, Parviz et al. · 2021 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Targeting Mitochondrial Biogenesis with Polyphenol Compounds

Authors: Chodari, Leila; Aytemir, Mutlu Dilsiz; Vahedi, Parviz; Alipour, Mahdieh; Vahed, Sepideh Zununi; Khatibi, Seyed Mahdi Hosseiniyan; Ahmadian, Elham; Ardalan, Mohammadreza; Eftekhari, Aziz

Year: 2021

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2021/4946711

Paper Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.

Chen, Hongyu; Chen, Baoxia; Li, Baolong et al. · 2021 · Oxidative medicine and cellular longevity · DOI

Full title: Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.

Authors: Chen, Hongyu; Chen, Baoxia; Li, Baolong; Luo, Xiaobin; Wu, Hongqiang; Zhang, Chenxi; Liu, Junling; Jiang, Jingtao; Zhao, Bin

Year: 2021

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2021/6611668

Paper Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux.

Zhang, Qi-Qi; Luo, Lu; Liu, Mei-Xi et al. · 2022 · Mediators of inflammation · DOI

Full title: Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux.

Authors: Zhang, Qi-Qi; Luo, Lu; Liu, Mei-Xi; Wang, Chuan-Jie; Wu, Yi; Yu, Ke-Wei

Year: 2022

Venue: Mediators of inflammation

DOI: https://doi.org/10.1155/2022/2396487

Paper Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.

Zuo, Xiaoshuang; Wei, Xinghui; Ju, Cheng et al. · 2022 · Oxidative medicine and cellular longevity · DOI

Full title: Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.

Authors: Zuo, Xiaoshuang; Wei, Xinghui; Ju, Cheng; Wang, Xuankang; Zhang, Zhihao; Ma, Yangguang; Zhu, Zhijie; Li, Xin; Song, Zhiwen; Luo, Liang; Hu, Xueyu; Wang, Zhe

Year: 2022

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2022/7223353

Paper Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy.

Ye, Pingting; Feng, Lei; Zhang, Dan et al. · 2023 · Stem cells international · DOI

Full title: Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy.

Authors: Ye, Pingting; Feng, Lei; Zhang, Dan; Li, Ruihao; Wen, Yixuan; Tong, Xiaohan; Shi, Shuo; Dong, Chunyan

Year: 2023

Venue: Stem cells international

DOI: https://doi.org/10.1155/2023/1429642

Paper miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway.

Zhu, Zhongsheng; Li, Jinyu; Tong, Rui et al. · 2021 · Cardiology research and practice · DOI

Full title: miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway.

Authors: Zhu, Zhongsheng; Li, Jinyu; Tong, Rui; Zhang, Xiaorong; Yu, Bo

Year: 2021

Venue: Cardiology research and practice

DOI: https://doi.org/10.1155/2021/9963258

Paper Protective Effect of Keluoxin against Diabetic Nephropathy in Type 2 Diabetic Mellitus Models.

Yang, Xiaomei; Han, Xuke; Wen, Qing et al. · 2021 · Evidence-based complementary and alternative medicine : eCAM · DOI

Full title: Protective Effect of Keluoxin against Diabetic Nephropathy in Type 2 Diabetic Mellitus Models.

Authors: Yang, Xiaomei; Han, Xuke; Wen, Qing; Qiu, Xianliang; Deng, Huan; Chen, Qiu

Year: 2021

Venue: Evidence-based complementary and alternative medicine : eCAM

DOI: https://doi.org/10.1155/2021/8455709

Paper ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.

Zhang, Ziqiang; Zhang, Mengyu; Zhang, Zhixiang et al. · 2022 · International journal of endocrinology · DOI

Full title: ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.

Authors: Zhang, Ziqiang; Zhang, Mengyu; Zhang, Zhixiang; Sun, Yingying; Wang, Jiajia; Chang, Chenhao; Zhu, Xinyan; Li, Monan; Liu, Yumei

Year: 2022

Venue: International journal of endocrinology

DOI: https://doi.org/10.1155/2022/5861553

Paper Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

Law, Betty Yuen Kwan; Wang, Mingfu; Ma, Dik‐Lung et al. · 2010 · Molecular Cancer Therapeutics · DOI

Full title: Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

Authors: Law, Betty Yuen Kwan; Wang, Mingfu; Ma, Dik‐Lung; Al‐Mousa, Fawaz; Michelangeli, Francesco; Cheng, Suk‐Hang; Ng, Margaret H.L.; To, Ka‐Fai; Mok, Anthony Y.F.; Ko, Rebecca Y. Y.; Lam, Sze Kui; Chen, Feng; Che, Chi‐Ming; Chiu, Pauline; Ko, Ben C.B.

Year: 2010

Venue: Molecular Cancer Therapeutics

DOI: https://doi.org/10.1158/1535-7163.mct-09-0700

Paper Histone Deacetylase Inhibitors Reduce Cysts by Activating Autophagy in Polycystic Kidney Disease.

Sun, Liping; Hu, Chaofeng; Zhang, Xinzhou · 2019 · Kidney diseases (Basel, Switzerland) · DOI

Full title: Histone Deacetylase Inhibitors Reduce Cysts by Activating Autophagy in Polycystic Kidney Disease.

Authors: Sun, Liping; Hu, Chaofeng; Zhang, Xinzhou

Year: 2019

Venue: Kidney diseases (Basel, Switzerland)

DOI: https://doi.org/10.1159/000499368

Paper Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.

Li, Shuai; Jiang, Yizhou; Xing, Xingan et al. · 2021 · Oxidative medicine and cellular longevity · DOI

Full title: Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.

Authors: Li, Shuai; Jiang, Yizhou; Xing, Xingan; Lin, Ruohong; Li, Qin; Zhou, Wenshu; Qiu, Wei; Zheng, Wenhua

Year: 2021

Venue: Oxidative medicine and cellular longevity

DOI: https://doi.org/10.1155/2021/7654143

Paper Ischemic Preconditioning Alleviates Mouse Renal Ischemia/Reperfusion Injury by Enhancing Autophagy Activity of Proximal Tubular Cells.

Zhang, Shun; Xia, Weimin; Duan, Huangqi et al. · 2022 · Kidney diseases (Basel, Switzerland) · DOI

Full title: Ischemic Preconditioning Alleviates Mouse Renal Ischemia/Reperfusion Injury by Enhancing Autophagy Activity of Proximal Tubular Cells.

Authors: Zhang, Shun; Xia, Weimin; Duan, Huangqi; Li, Xinyan; Qian, Subo; Shen, Haibo

Year: 2022

Venue: Kidney diseases (Basel, Switzerland)

DOI: https://doi.org/10.1159/000521850

Paper Down-Regulation of Lncrna MALAT1 Attenuates Neuronal Cell Death Through Suppressing Beclin1-Dependent Autophagy by Regulating Mir-30a in Cerebral Ischemic Stroke

Guo, Dong; Ma, Ji; Lei, Yan et al. · 2017 · Cellular Physiology and Biochemistry · DOI

Full title: Down-Regulation of Lncrna MALAT1 Attenuates Neuronal Cell Death Through Suppressing Beclin1-Dependent Autophagy by Regulating Mir-30a in Cerebral Ischemic Stroke

Authors: Guo, Dong; Ma, Ji; Lei, Yan; Li, Tengfei; Li, Zhiguo; Han, Xinwei; Shui, Shaofeng

Year: 2017

Venue: Cellular Physiology and Biochemistry

DOI: https://doi.org/10.1159/000480337

Paper Dihydrotanshinone I Increase Amyloid-β Clearance and Decrease Tau Phosphorylation via Enhancing Autophagy.

Bao, Zhonglei; Zhang, Huixue; Jiao, Hong et al. · 2020 · Pharmacology · DOI

Full title: Dihydrotanshinone I Increase Amyloid-β Clearance and Decrease Tau Phosphorylation via Enhancing Autophagy.

Authors: Bao, Zhonglei; Zhang, Huixue; Jiao, Hong; Chu, Xiaojie; Fu, Jin; Wang, Lihua

Year: 2020

Venue: Pharmacology

DOI: https://doi.org/10.1159/000503792

Paper AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy.

Chen, Zhe; Jin, Tao; Lu, Yong · 2016 · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · DOI

Full title: AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy.

Authors: Chen, Zhe; Jin, Tao; Lu, Yong

Year: 2016

Venue: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

DOI: https://doi.org/10.1159/000453147

Paper Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.

Tu, Ji; Li, Wentian; Li, Shuai et al. · 2018 · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · DOI

Full title: Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.

Authors: Tu, Ji; Li, Wentian; Li, Shuai; Liu, Wei; Zhang, Yukun; Wu, Xinghuo; Luo, Rongjin; Hua, Wenbin; Wang, Kun; Song, Yu; Kang, Liang; Yang, Wen; Yang, Shuhua; Yang, Cao

Year: 2018

Venue: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

DOI: https://doi.org/10.1159/000487970

Paper Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis.

Packer, Milton · 2022 · Circulation · DOI

Full title: Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis.

Authors: Packer, Milton

Year: 2022

Venue: Circulation

DOI: https://doi.org/10.1161/CIRCULATIONAHA.122.061732

Paper Preliminary Study on Platelet-Rich Plasma Enhancing Autophagy Level and Promoting Hair Growth in Androgenetic Alopecia Model Mice.

Xiao, Ling; Chen, Wei; Liu, Siwei et al. · 2025 · Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · DOI

Full title: Preliminary Study on Platelet-Rich Plasma Enhancing Autophagy Level and Promoting Hair Growth in Androgenetic Alopecia Model Mice.

Authors: Xiao, Ling; Chen, Wei; Liu, Siwei; Xu, Haixia; Hou, Li; Tian, Li

Year: 2025

Venue: Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

DOI: https://doi.org/10.1159/000549505

Paper Dry Age-Related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging

Rickman, Catherine Bowes; Farsiu, Sina; Toth, Cynthia A. et al. · 2013 · Investigative Ophthalmology & Visual Science · DOI

Full title: Dry Age-Related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging

Authors: Rickman, Catherine Bowes; Farsiu, Sina; Toth, Cynthia A.; Klingeborn, Mikael

Year: 2013

Venue: Investigative Ophthalmology & Visual Science

DOI: https://doi.org/10.1167/iovs.13-12757

Paper Cyclovirobuxine D Brain-Targeted Liposomes Improve Cerebral Ischemia-Reperfusion Injury via Anti-Oxidant Stress and Activating Autophagy.

Yang, Fang; Ren, Lingzhi; Liu, Tuo et al. · 2022 · Journal of biomedical nanotechnology · DOI

Full title: Cyclovirobuxine D Brain-Targeted Liposomes Improve Cerebral Ischemia-Reperfusion Injury via Anti-Oxidant Stress and Activating Autophagy.

Authors: Yang, Fang; Ren, Lingzhi; Liu, Tuo; Lu, Xiangyi; Liu, Chang; Yu, Yang; Chen, Zhilian; Long, Yongling

Year: 2022

Venue: Journal of biomedical nanotechnology

DOI: https://doi.org/10.1166/jbn.2022.3327

Paper microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.

Li, Yan; Jiang, Jingjing; Liu, Wei et al. · 2018 · Proceedings of the National Academy of Sciences of the United States of America · DOI

Full title: microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.

Authors: Li, Yan; Jiang, Jingjing; Liu, Wei; Wang, Hui; Zhao, Lei; Liu, Shengnan; Li, Peng; Zhang, Shengjie; Sun, Chao; Wu, Yuting; Yu, Shuxian; Li, Xihua; Zhang, Hui; Qian, Haifeng; Zhang, Duo; Guo, Feifan; Zhai, Qiwei; Ding, Qiurong; Wang, Li; Ying, Hao

Year: 2018

Venue: Proceedings of the National Academy of Sciences of the United States of America

DOI: https://doi.org/10.1073/pnas.1803377115

Paper Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis

Wang, Guohao; Liu, Xudong; Gaertig, Marta A. et al. · 2016 · Proceedings of the National Academy of Sciences · DOI

Full title: Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis

Authors: Wang, Guohao; Liu, Xudong; Gaertig, Marta A.; Li, Shihua; Li, Xiao‐Jiang

Year: 2016

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1524575113

Paper Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance

Hegazy, Ahmed M.; Yamada, Daisuke; Kobayashi, Masahiko et al. · 2016 · Journal of Biological Chemistry · DOI

Full title: Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance

Authors: Hegazy, Ahmed M.; Yamada, Daisuke; Kobayashi, Masahiko; Kohno, Susumu; Ueno, Masaya; Ali, Mohamed Ashraf; Ohta, Kumiko; Tadokoro, Yuko; Ino, Yasushi; Todo, Tomoki; Soga, Tomoyoshi; Takahashi, Chiaki; Hirao, Atsushi

Year: 2016

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.m116.734756

Paper Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin

Xiao, Bin; Goh, Jian-Yuan; Xiao, Lin et al. · 2017 · Journal of Biological Chemistry · DOI

Full title: Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin

Authors: Xiao, Bin; Goh, Jian-Yuan; Xiao, Lin; Xian, Hongxu; Lim, Kah‐Leong; Liou, Yih‐Cherng

Year: 2017

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.m117.787739

Paper Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model

Avrahami, Limor; Farfara, Dorit; Shaham-Kol, Maya et al. · 2012 · Journal of Biological Chemistry · DOI

Full title: Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model

Authors: Avrahami, Limor; Farfara, Dorit; Shaham-Kol, Maya; Vassar, Robert; Frenkel, Dan; Eldar-Finkelman, Hagit

Year: 2012

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.m112.409250

Paper Novel therapeutic strategies for stroke: The role of autophagy.

Nabavi, Seyed Fazel; Sureda, Antoni; Sanches-Silva, Ana et al. · 2019 · Critical reviews in clinical laboratory sciences · DOI

Full title: Novel therapeutic strategies for stroke: The role of autophagy.

Authors: Nabavi, Seyed Fazel; Sureda, Antoni; Sanches-Silva, Ana; Pandima Devi, Kasi; Ahmed, Touqeer; Shahid, Momina; Sobarzo-Sánchez, Eduardo; Dacrema, Marco; Daglia, Maria; Braidy, Nady; Vacca, Rosa Anna; Berindan-Neagoe, Ioana; Gulei, Diana; Barreca, Davide; Banach, Maciej; Nabavi, Seyed Mohammad; Dehpour, Ahmad Reza; Shirooie, Samira

Year: 2019

Venue: Critical reviews in clinical laboratory sciences

DOI: https://doi.org/10.1080/10408363.2019.1575333

Paper Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.

Hidvegi, Tunda; Stolz, Donna B; Alcorn, John F et al. · 2015 · The Journal of biological chemistry · DOI

Full title: Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.

Authors: Hidvegi, Tunda; Stolz, Donna B; Alcorn, John F; Yousem, Samuel A; Wang, Jieru; Leme, Adriana S; Houghton, A McGarry; Hale, Pamela; Ewing, Michael; Cai, Houming; Garchar, Evelyn Akpadock; Pastore, Nunzia; Annunziata, Patrizia; Kaminski, Naftali; Pilewski, Joseph; Shapiro, Steven D; Pak, Stephen C; Silverman, Gary A; Brunetti-Pierri, Nicola; Perlmutter, David H

Year: 2015

Venue: The Journal of biological chemistry

DOI: https://doi.org/10.1074/jbc.M115.691253

Paper Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway.

Liu, Honghong; Wang, Jiao; Yue, Guanru et al. · 2024 · Renal failure · DOI

Full title: Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway.

Authors: Liu, Honghong; Wang, Jiao; Yue, Guanru; Xu, Jixiong

Year: 2024

Venue: Renal failure

DOI: https://doi.org/10.1080/0886022X.2024.2303396

Paper SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.

Wei, Zong-Bo; Yuan, Ye-Feng; Jaouen, Florence et al. · 2016 · Autophagy · DOI

Full title: SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.

Authors: Wei, Zong-Bo; Yuan, Ye-Feng; Jaouen, Florence; Ma, Mei-Sheng; Hao, Chan-Juan; Zhang, Zhe; Chen, Quan; Yuan, Zengqiang; Yu, Li; Beurrier, Corinne; Li, Wei

Year: 2016

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2016.1179402

Paper Progressive endolysosomal deficits impair autophagic clearance beginning at early asymptomatic stages in fALS mice.

Xie, Yuxiang; Zhou, Bing; Lin, Mei-Yao et al. · 2015 · Autophagy · DOI

Full title: Progressive endolysosomal deficits impair autophagic clearance beginning at early asymptomatic stages in fALS mice.

Authors: Xie, Yuxiang; Zhou, Bing; Lin, Mei-Yao; Sheng, Zu-Hang

Year: 2015

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2015.1084460

Paper TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway.

Bae, Seong-Yeon; Byun, Sanguine; Bae, Soo Han et al. · 2017 · Autophagy · DOI

Full title: TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway.

Authors: Bae, Seong-Yeon; Byun, Sanguine; Bae, Soo Han; Min, Do Sik; Woo, Hyun Ae; Lee, Kyunglim

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2017.1287650

Paper Wild-type rabies virus induces autophagy in human and mouse neuroblastoma cell lines.

Peng, Jiaojiao; Zhu, Shenghe; Hu, Lili et al. · 2016 · Autophagy · DOI

Full title: Wild-type rabies virus induces autophagy in human and mouse neuroblastoma cell lines.

Authors: Peng, Jiaojiao; Zhu, Shenghe; Hu, Lili; Ye, Pingping; Wang, Yifei; Tian, Qin; Mei, Mingzhu; Chen, Hao; Guo, Xiaofeng

Year: 2016

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2016.1196315

Paper Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence.

Tai, Haoran; Wang, Zhe; Gong, Hui et al. · 2017 · Autophagy · DOI

Full title: Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence.

Authors: Tai, Haoran; Wang, Zhe; Gong, Hui; Han, Xiaojuan; Zhou, Jiao; Wang, Xiaobo; Wei, Xiawei; Ding, Yi; Huang, Ning; Qin, Jianqiong; Zhang, Jie; Wang, Shuang; Gao, Fei; Chrzanowska-Lightowlers, Zofia M; Xiang, Rong; Xiao, Hengyi

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2016.1247143

Paper Emerging connections between RNA and autophagy.

Frankel, Lisa B; Lubas, Michal; Lund, Anders H · 2017 · Autophagy · DOI

Full title: Emerging connections between RNA and autophagy.

Authors: Frankel, Lisa B; Lubas, Michal; Lund, Anders H

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2016.1222992

Paper Dietary spermidine for lowering high blood pressure.

Eisenberg, Tobias; Abdellatif, Mahmoud; Zimmermann, Andreas et al. · 2017 · Autophagy · DOI

Full title: Dietary spermidine for lowering high blood pressure.

Authors: Eisenberg, Tobias; Abdellatif, Mahmoud; Zimmermann, Andreas; Schroeder, Sabrina; Pendl, Tobias; Harger, Alexandra; Stekovic, Slaven; Schipke, Julia; Magnes, Christoph; Schmidt, Albrecht; Ruckenstuhl, Christoph; Dammbrueck, Christopher; Gross, Angelina S; Herbst, Viktoria; Carmona-Gutierrez, Didac; Pietrocola, Federico; Pieber, Thomas R; Sigrist, Stephan J; Linke, Wolfgang A; Mühlfeld, Christian; Sadoshima, Junichi; Dengjel, Joern; Kiechl, Stefan; Kroemer, Guido; Sedej, Simon; Madeo, Frank

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2017.1280225

Paper Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.

Zhu, Mingwei; Zhang, Sheng; Tian, Xiaolin et al. · 2017 · Autophagy · DOI

Full title: Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.

Authors: Zhu, Mingwei; Zhang, Sheng; Tian, Xiaolin; Wu, Chunlai

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2017.1362524

Paper Anti- and pro-microbial roles of autophagy in plant-bacteria interactions.

Üstün, Suayib; Hofius, Daniel · 2018 · Autophagy · DOI

Full title: Anti- and pro-microbial roles of autophagy in plant-bacteria interactions.

Authors: Üstün, Suayib; Hofius, Daniel

Year: 2018

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2018.1475817

Paper HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease.

Fu, Yuhua; Sun, Xiaoli; Lu, Boxun · 2018 · Autophagy · DOI

Full title: HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease.

Authors: Fu, Yuhua; Sun, Xiaoli; Lu, Boxun

Year: 2018

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2017.1393130

Paper Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).

Zheng, Xiaoyan; Lin, Wenjia; Jiang, Yimin et al. · 2021 · Autophagy · DOI

Full title: Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).

Authors: Zheng, Xiaoyan; Lin, Wenjia; Jiang, Yimin; Lu, Kejia; Wei, Wenjing; Huo, Qingwei; Cui, Shaoyang; Yang, Xifei; Li, Min; Xu, Nenggui; Tang, Chunzhi; Song, Ju-Xian

Year: 2021

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2021.1886720

Paper Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy.

Chen, Lei-Lei; Wang, Yong-Bo; Song, Ju-Xian et al. · 2017 · Autophagy · DOI

Full title: Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy.

Authors: Chen, Lei-Lei; Wang, Yong-Bo; Song, Ju-Xian; Deng, Wan-Kun; Lu, Jia-Hong; Ma, Li-Li; Yang, Chuan-Bin; Li, Min; Xue, Yu

Year: 2017

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2017.1371393

Paper Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy.

Tsakiri, Eleni N; Gumeni, Sentiljana; Vougas, Konstantinos et al. · 2019 · Autophagy · DOI

Full title: Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy.

Authors: Tsakiri, Eleni N; Gumeni, Sentiljana; Vougas, Konstantinos; Pendin, Diana; Papassideri, Issidora; Daga, Andrea; Gorgoulis, Vassilis; Juhász, Gábor; Scorrano, Luca; Trougakos, Ioannis P

Year: 2019

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2019.1596477

Paper STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.

Zhou, Cefan; Qian, Xuehong; Hu, Miao et al. · 2020 · Autophagy · DOI

Full title: STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.

Authors: Zhou, Cefan; Qian, Xuehong; Hu, Miao; Zhang, Rui; Liu, Nanxi; Huang, Yuan; Yang, Jing; Zhang, Juan; Bai, Hua; Yang, Yuyan; Wang, Yefu; Ali, Declan; Michalak, Marek; Chen, Xing-Zhen; Tang, Jingfeng

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2019.1687212

Paper CDKN1B/p27 regulates autophagy via the control of Ragulator and MTOR activity in amino acid-deprived cells.

Nowosad, Ada; Besson, Arnaud · 2020 · Autophagy · DOI

Full title: CDKN1B/p27 regulates autophagy via the control of Ragulator and MTOR activity in amino acid-deprived cells.

Authors: Nowosad, Ada; Besson, Arnaud

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1831217

Paper High-throughput screening of functional deubiquitinating enzymes in autophagy.

Tian, Shuo; Jin, Shouheng; Wu, Yaoxing et al. · 2021 · Autophagy · DOI

Full title: High-throughput screening of functional deubiquitinating enzymes in autophagy.

Authors: Tian, Shuo; Jin, Shouheng; Wu, Yaoxing; Liu, Tao; Luo, Man; Ou, Jiayu; Xie, Weihong; Cui, Jun

Year: 2021

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1761652

Paper Autophagy-dependent regulation of skeletal muscle regeneration and strength by a RHOGEF.

You, Jae-Sung; Chen, Jie · 2021 · Autophagy · DOI

Full title: Autophagy-dependent regulation of skeletal muscle regeneration and strength by a RHOGEF.

Authors: You, Jae-Sung; Chen, Jie

Year: 2021

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2021.1886721

Paper Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

Jiang, Jingwen; Zhang, Lu; Chen, Hai‐Ning et al. · 2019 · Autophagy · DOI

Full title: Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

Authors: Jiang, Jingwen; Zhang, Lu; Chen, Hai‐Ning; Lei, Yunlong; Zhang, Tao; Wang, Yuelong; Jin, Ping; Jiang, Lan; Zhou, Li; Huang, Zhao; Li, Bowen; Liu, Yuan; Gao, Wei; Xie, Ke; Zhou, Liangxue; Nice, Edouard C.; Peng, Yong; Cao, Yihai; Wei, Yuquan; Wang, Kui; Huang, Canhua

Year: 2019

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2019.1598752

Paper Coronavirus interactions with the cellular autophagy machinery.

Miller, Katelyn; McGrath, Marisa E; Hu, Zhiqiang et al. · 2020 · Autophagy · DOI

Full title: Coronavirus interactions with the cellular autophagy machinery.

Authors: Miller, Katelyn; McGrath, Marisa E; Hu, Zhiqiang; Ariannejad, Sohha; Weston, Stuart; Frieman, Matthew; Jackson, William T

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1817280

Paper Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E).

Vessey, Kirstan A; Jobling, Andrew I; Tran, Mai X et al. · 2022 · Autophagy · DOI

Full title: Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E).

Authors: Vessey, Kirstan A; Jobling, Andrew I; Tran, Mai X; Wang, Anna Y; Greferath, Ursula; Fletcher, Erica L

Year: 2022

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2034131

Paper Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.

Akwa, Yvette; Di Malta, Chiara; Zallo, Fátima et al. · 2023 · Autophagy · DOI

Full title: Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.

Authors: Akwa, Yvette; Di Malta, Chiara; Zallo, Fátima; Gondard, Elise; Lunati, Adele; Diaz-de-Grenu, Lara Z; Zampelli, Angela; Boiret, Anne; Santamaria, Sara; Martinez-Preciado, Maialen; Cortese, Katia; Kordower, Jeffrey H; Matute, Carlos; Lozano, Andres M; Capetillo-Zarate, Estibaliz; Vaccari, Thomas; Settembre, Carmine; Baulieu, Etienne E; Tampellini, Davide

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2095791

Paper Regulation of LC3B levels by ubiquitination and proteasomal degradation.

Jia, Rui; Bonifacino, Juan S · 2020 · Autophagy · DOI

Full title: Regulation of LC3B levels by ubiquitination and proteasomal degradation.

Authors: Jia, Rui; Bonifacino, Juan S

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2019.1709766

Paper Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease.

Zhang, Wei; Wang, Jigang; Yang, Chuanbin · 2022 · Autophagy · DOI

Full title: Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease.

Authors: Zhang, Wei; Wang, Jigang; Yang, Chuanbin

Year: 2022

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2046437

Paper Excitation-transcription coupling via synapto-nuclear signaling triggers autophagy for synaptic turnover and long-lasting synaptic depression.

Pan, Yue; Zhou, Guangjun; Li, Wenwen et al. · 2021 · Autophagy · DOI

Full title: Excitation-transcription coupling via synapto-nuclear signaling triggers autophagy for synaptic turnover and long-lasting synaptic depression.

Authors: Pan, Yue; Zhou, Guangjun; Li, Wenwen; He, Xingzhi; Li, Cuicui; Li, Yanjun; Li, Tao; Hu, Hailan; Ma, Huan

Year: 2021

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2021.1964888

Paper Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease.

Cen, Xufeng; Xu, Xiaoyan; Xia, Hongguang · 2021 · Autophagy · DOI

Full title: Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease.

Authors: Cen, Xufeng; Xu, Xiaoyan; Xia, Hongguang

Year: 2021

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1860542

Paper TTR (transthyretin) leads the autophagy disaster relief team against TARDBP/TDP-43 proteinopathy.

Chu, Yuan-Ping; Ho, Pei-Chuan; Tsai, Kuen-Jer · 2023 · Autophagy · DOI

Full title: TTR (transthyretin) leads the autophagy disaster relief team against TARDBP/TDP-43 proteinopathy.

Authors: Chu, Yuan-Ping; Ho, Pei-Chuan; Tsai, Kuen-Jer

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2167690

Paper LYECs: lysosome-enhancing compounds as potential therapeutic approaches for Alzheimer disease.

Yin, Limin; Zhou, Yu; Liu, Hong et al. · 2023 · Autophagy · DOI

Full title: LYECs: lysosome-enhancing compounds as potential therapeutic approaches for Alzheimer disease.

Authors: Yin, Limin; Zhou, Yu; Liu, Hong; Li, Yang

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2131247

Paper Modeling Huntington disease through microRNA-mediated neuronal reprogramming identifies age-associated autophagy dysfunction driving the onset of neurodegeneration.

Oh, Young Mi; Lee, Seong Won; Yoo, Andrew S · 2023 · Autophagy · DOI

Full title: Modeling Huntington disease through microRNA-mediated neuronal reprogramming identifies age-associated autophagy dysfunction driving the onset of neurodegeneration.

Authors: Oh, Young Mi; Lee, Seong Won; Yoo, Andrew S

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2175572

Paper Optogenetic manipulation of lysosomal physiology and autophagic activity.

Zeng, Wenping; Li, Canjun; Qu, Lili et al. · 2024 · Autophagy · DOI

Full title: Optogenetic manipulation of lysosomal physiology and autophagic activity.

Authors: Zeng, Wenping; Li, Canjun; Qu, Lili; Cang, Chunlei

Year: 2024

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2024.2392464

Paper PINK1-dependent NFKB signaling contributes to amyloid pathology in Alzheimer disease.

Du, Fang; Yu, Qing; Hu, Gang et al. · 2025 · Autophagy · DOI

Full title: PINK1-dependent NFKB signaling contributes to amyloid pathology in Alzheimer disease.

Authors: Du, Fang; Yu, Qing; Hu, Gang; Lin, Chyuan-Sheng; ShiDu Yan, Shirley

Year: 2025

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2025.2463322

Paper Aerobic exercise attenuates autophagy-lysosomal flux deficits by ADRB2/β2-adrenergic receptor-mediated V-ATPase assembly factor VMA21 signaling in APP-PSEN1/PS1 mice.

Wu, Jia-Jun; Yu, Haitao; Bi, Shu-Guang et al. · 2024 · Autophagy · DOI

Full title: Aerobic exercise attenuates autophagy-lysosomal flux deficits by ADRB2/β2-adrenergic receptor-mediated V-ATPase assembly factor VMA21 signaling in APP-PSEN1/PS1 mice.

Authors: Wu, Jia-Jun; Yu, Haitao; Bi, Shu-Guang; Wang, Zhong-Xuan; Gong, Juan; Mao, Yu-Ming; Wang, Fang-Zhou; Zhang, Yu-Qi; Nie, Yun-Juan; Chai, Gao-Shang

Year: 2024

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2281134

Paper Involvement of acetylation of ATG4B in controlling autophagy induction.

Xiong, Haojun; Sun, Liangbo; Lian, Jiqin et al. · 2023 · Autophagy · DOI

Full title: Involvement of acetylation of ATG4B in controlling autophagy induction.

Authors: Xiong, Haojun; Sun, Liangbo; Lian, Jiqin; He, Fengtian

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2117887

Paper CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.

Zhou, Yuanzhang; Liu, Yang; Kang, Zhengwei et al. · 2023 · Autophagy · DOI

Full title: CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.

Authors: Zhou, Yuanzhang; Liu, Yang; Kang, Zhengwei; Yao, Hang; Song, Nanshan; Wang, Min; Song, Chenghuan; Zhang, Kezhong; Ding, Jianhua; Tang, Juanjuan; Hu, Gang; Lu, Ming

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2196889

Paper Enhancing neuronal reticulophagy: a strategy for combating aging and APP toxicity.

Mou, Wenqing; Cui, Yixian · 2024 · Autophagy · DOI

Full title: Enhancing neuronal reticulophagy: a strategy for combating aging and APP toxicity.

Authors: Mou, Wenqing; Cui, Yixian

Year: 2024

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2024.2375086

Paper R406 and its structural analogs reduce SNCA/α-synuclein levels via autophagic degradation.

Zhong, Chao; Gao, Xiaoge; Chen, Qi et al. · 2025 · Autophagy · DOI

Full title: R406 and its structural analogs reduce SNCA/α-synuclein levels via autophagic degradation.

Authors: Zhong, Chao; Gao, Xiaoge; Chen, Qi; Guan, Bowen; Wu, Wanli; Ma, Zhiqiang; Tao, Mengdan; Liu, Xihuan; Ding, Yu; Fei, Yiyan; Liu, Yan; Lu, Boxun; Li, Zhaoyang

Year: 2025

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2025.2483886

Paper MCOLN/TRPML channels in the regulation of MTORC1 and autophagy.

Huang, Peng; Dong, Rose Yang; Wang, Pingping et al. · 2024 · Autophagy · DOI

Full title: MCOLN/TRPML channels in the regulation of MTORC1 and autophagy.

Authors: Huang, Peng; Dong, Rose Yang; Wang, Pingping; Xu, Mengnan; Sun, Xue; Dong, Xian-Ping

Year: 2024

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2300922

Paper TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux.

Zhao, Dongdong; Qiang, Lihua; Lei, Zehui et al. · 2024 · Autophagy · DOI

Full title: TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux.

Authors: Zhao, Dongdong; Qiang, Lihua; Lei, Zehui; Ge, Pupu; Lu, Zhe; Wang, Yiru; Zhang, Xinwen; Qiang, Yuyun; Li, Bingxi; Pang, Yu; Zhang, Lingqiang; Liu, Cui Hua; Wang, Jing

Year: 2024

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2024.2321831

Paper HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation.

Miao, Chunhui; Zhang, Yajie; Yu, Mingyu et al. · 2023 · Autophagy · DOI

Full title: HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation.

Authors: Miao, Chunhui; Zhang, Yajie; Yu, Mingyu; Wei, Yuting; Dong, Cheng; Pei, Geng; Xiao, Yawen; Yang, Jianming; Yao, Zhi; Wang, Quan

Year: 2023

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2023.2223468

Paper Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity.

Ntsapi, Claudia M; du Toit, Andre; Loos, Ben · 2022 · Autophagy reports · DOI

Full title: Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity.

Authors: Ntsapi, Claudia M; du Toit, Andre; Loos, Ben

Year: 2022

Venue: Autophagy reports

DOI: https://doi.org/10.1080/27694127.2022.2082631

Paper Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection.

Rader, Anusca G; Cloherty, Alexandra P M; Patel, Kharishma S et al. · 2025 · Autophagy reports · DOI

Full title: Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection.

Authors: Rader, Anusca G; Cloherty, Alexandra P M; Patel, Kharishma S; Almandawi, Dima D A; Perez-Vargas, Jimena; Wildenberg, Manon E; Muncan, Vanesa; Schreurs, Renée R C E; Jean, François; Ribeiro, Carla M S

Year: 2025

Venue: Autophagy reports

DOI: https://doi.org/10.1080/27694127.2025.2514232

Paper VAMP8 stabilization by DRAM1 enables autophagosome-lysosome fusion and promotes metastatic extravasation.

Zhang, Rui; Torraca, Vincenzo; Yan, Chaojun et al. · 2025 · Autophagy · DOI

Full title: VAMP8 stabilization by DRAM1 enables autophagosome-lysosome fusion and promotes metastatic extravasation.

Authors: Zhang, Rui; Torraca, Vincenzo; Yan, Chaojun; Lyu, Hao; Xiao, Shuai; Guo, Dong; Zhang, Qi; Zhou, Cefan; Tang, Jingfeng

Year: 2025

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2025.2554794

Paper Shaping proteostasis at the cellular, tissue, and organismal level

Sala, Ambre J.; Bott, Laura C.; Morimoto, Richard I. · 2017 · The Journal of Cell Biology · DOI

Full title: Shaping proteostasis at the cellular, tissue, and organismal level

Authors: Sala, Ambre J.; Bott, Laura C.; Morimoto, Richard I.

Year: 2017

Venue: The Journal of Cell Biology

DOI: https://doi.org/10.1083/jcb.201612111

Paper Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes.

Ghosh, Rajeshwary; Pattison, J Scott · 2023 · Autophagy reports · DOI

Full title: Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes.

Authors: Ghosh, Rajeshwary; Pattison, J Scott

Year: 2023

Venue: Autophagy reports

DOI: https://doi.org/10.1080/27694127.2023.2174337

Paper The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B.

Lin, Yuchieh Jay; Huang, Li-Ting; Ke, Po-Yuan et al. · 2025 · The Journal of cell biology · DOI

Full title: The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B.

Authors: Lin, Yuchieh Jay; Huang, Li-Ting; Ke, Po-Yuan; Chen, Guang-Chao

Year: 2025

Venue: The Journal of cell biology

DOI: https://doi.org/10.1083/jcb.202407014

Paper TRIMming down Mycobacterium tuberculosis replication: TRIM32 is required for bacterial ubiquitination and autophagy induction in macrophages.

Romagnoli, Alessandra; Di Rienzo, Martina; Piacentini, Mauro et al. · 2023 · Autophagy reports · DOI

Full title: TRIMming down Mycobacterium tuberculosis replication: TRIM32 is required for bacterial ubiquitination and autophagy induction in macrophages.

Authors: Romagnoli, Alessandra; Di Rienzo, Martina; Piacentini, Mauro; Fimia, Gian Maria

Year: 2023

Venue: Autophagy reports

DOI: https://doi.org/10.1080/27694127.2023.2278120

Paper lncRNA H19 promotes glioblastoma multiforme development by activating autophagy by sponging miR-491-5p.

Wang, Guo; Lin, Xiaoyan; Han, Han et al. · 2022 · Bioengineered · DOI

Full title: lncRNA H19 promotes glioblastoma multiforme development by activating autophagy by sponging miR-491-5p.

Authors: Wang, Guo; Lin, Xiaoyan; Han, Han; Zhang, Hongxu; Li, Xiaoli; Feng, Mei; Jiang, Chunming

Year: 2022

Venue: Bioengineered

DOI: https://doi.org/10.1080/21655979.2022.2065947

Paper Deacetylation of HSC70 by SIRT2 promotes chaperone mediated autophagy.

Ahn, Byunghyun; Chen, Wenzhe; Shi, Wenbiao et al. · 2025 · Autophagy reports · DOI

Full title: Deacetylation of HSC70 by SIRT2 promotes chaperone mediated autophagy.

Authors: Ahn, Byunghyun; Chen, Wenzhe; Shi, Wenbiao; Shrestha, Ruben; Hu, Fenghua; Lin, Hening

Year: 2025

Venue: Autophagy reports

DOI: https://doi.org/10.1080/27694127.2025.2580781

Paper Lithium induces autophagy by inhibiting inositol monophosphatase.

Sarkar, Sovan; Floto, R Andres; Berger, Zdenek et al. · 2005 · The Journal of cell biology · DOI

Full title: Lithium induces autophagy by inhibiting inositol monophosphatase.

Authors: Sarkar, Sovan; Floto, R Andres; Berger, Zdenek; Imarisio, Sara; Cordenier, Axelle; Pasco, Matthieu; Cook, Lynnette J; Rubinsztein, David C

Year: 2005

Venue: The Journal of cell biology

DOI: https://doi.org/10.1083/jcb.200504035

Paper N-degron-mediated ATG8 isoform switching controls plant thermotolerance.

Kim, Seu Ha; Park, Ohkmae K · 2025 · Autophagy · DOI

Full title: N-degron-mediated ATG8 isoform switching controls plant thermotolerance.

Authors: Kim, Seu Ha; Park, Ohkmae K

Year: 2025

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2025.2552904

Paper The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

Braak, Heiko; Tredici, Kelly Del · 2015 · Brain · DOI

Full title: The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

Authors: Braak, Heiko; Tredici, Kelly Del

Year: 2015

Venue: Brain

DOI: https://doi.org/10.1093/brain/awv236

Paper A single pathway targets several health challenges of the elderly.

Bahr, Ben A · 2014 · Rejuvenation research · DOI

Full title: A single pathway targets several health challenges of the elderly.

Authors: Bahr, Ben A

Year: 2014

Venue: Rejuvenation research

DOI: https://doi.org/10.1089/rej.2014.1585

Paper C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy.

Wei, Pengfei; Zhang, Li; Lu, Yang et al. · 2010 · Nanotechnology · DOI

Full title: C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy.

Authors: Wei, Pengfei; Zhang, Li; Lu, Yang; Man, Na; Wen, Longping

Year: 2010

Venue: Nanotechnology

DOI: https://doi.org/10.1088/0957-4484/21/49/495101

Paper Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits.

Yang, Dun-Sheng; Stavrides, Philip; Saito, Mitsuo et al. · 2014 · Brain : a journal of neurology · DOI

Full title: Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits.

Authors: Yang, Dun-Sheng; Stavrides, Philip; Saito, Mitsuo; Kumar, Asok; Rodriguez-Navarro, Jose A; Pawlik, Monika; Huo, Chunfeng; Walkley, Steven U; Saito, Mariko; Cuervo, Ana M; Nixon, Ralph A

Year: 2014

Venue: Brain : a journal of neurology

DOI: https://doi.org/10.1093/brain/awu278

Paper Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis

Grootaert, Mandy O. J.; Moulis, Manon; Roth, Lynn et al. · 2018 · Cardiovascular Research · DOI

Full title: Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis

Authors: Grootaert, Mandy O. J.; Moulis, Manon; Roth, Lynn; Martinet, Wim; Vindis, Cécile; Bennett, Martin R.; Meyer, Guido R.Y. De

Year: 2018

Venue: Cardiovascular Research

DOI: https://doi.org/10.1093/cvr/cvy007

Paper Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.

Zhang, Jing; Zhang, Wanju; Ren, Lehao et al. · 2020 · FEMS microbiology letters · DOI

Full title: Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.

Authors: Zhang, Jing; Zhang, Wanju; Ren, Lehao; He, Yanchao; Mei, Zhoufang; Feng, Jingjing; Shi, Tianyun; Zhang, Huiying; Song, Zhigang; Jie, Zhijun

Year: 2020

Venue: FEMS microbiology letters

DOI: https://doi.org/10.1093/femsle/fnaa007

Paper Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.

Kong, Derek K; Georgescu, Serban P; Cano, Carla et al. · 2010 · Molecular biology of the cell · DOI

Full title: Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.

Authors: Kong, Derek K; Georgescu, Serban P; Cano, Carla; Aronovitz, Mark J; Iovanna, Juan Lucio; Patten, Richard D; Kyriakis, John M; Goruppi, Sandro

Year: 2010

Venue: Molecular biology of the cell

DOI: https://doi.org/10.1091/mbc.e09-09-0818

Paper (Poly)phenols protect from α-synuclein toxicity by reducing oxidative stress and promoting autophagy.

Macedo, Diana; Tavares, Lucélia; McDougall, Gordon J et al. · 2015 · Human molecular genetics · DOI

Full title: (Poly)phenols protect from α-synuclein toxicity by reducing oxidative stress and promoting autophagy.

Authors: Macedo, Diana; Tavares, Lucélia; McDougall, Gordon J; Vicente Miranda, Hugo; Stewart, Derek; Ferreira, Ricardo B; Tenreiro, Sandra; Outeiro, Tiago F; Santos, Cláudia N

Year: 2015

Venue: Human molecular genetics

DOI: https://doi.org/10.1093/hmg/ddu585

Paper Riptortus pedestris effector induces autophagy through interaction with ATG8, enhancing insect feeding.

Lu, Wangshan; Yang, Yuxia; Zhang, Yancong et al. · 2026 · Journal of experimental botany · DOI

Full title: Riptortus pedestris effector induces autophagy through interaction with ATG8, enhancing insect feeding.

Authors: Lu, Wangshan; Yang, Yuxia; Zhang, Yancong; Zhang, Qingsong; Ding, Lanping; Ai, Gan; Shen, Danyu; Dong, Yumei; Xia, Ai

Year: 2026

Venue: Journal of experimental botany

DOI: https://doi.org/10.1093/jxb/eraf461

Paper Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.

Osaka, Mayuko; Ito, Daisuke; Yagi, Takuya et al. · 2015 · Human molecular genetics · DOI

Full title: Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.

Authors: Osaka, Mayuko; Ito, Daisuke; Yagi, Takuya; Nihei, Yoshihiro; Suzuki, Norihiro

Year: 2015

Venue: Human molecular genetics

DOI: https://doi.org/10.1093/hmg/ddu575

Paper A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.

Ochaba, Joseph; Powers, Andrew F; Tremble, Kaitlyn A et al. · 2019 · Nucleic acids research · DOI

Full title: A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.

Authors: Ochaba, Joseph; Powers, Andrew F; Tremble, Kaitlyn A; Greenlee, Sarah; Post, Noah M; Matson, John E; MacLeod, A Robert; Guo, Shuling; Aghajan, Mariam

Year: 2019

Venue: Nucleic acids research

DOI: https://doi.org/10.1093/nar/gkz901

Paper Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Underwood, Benjamin R; Imarisio, Sara; Fleming, Angeleen et al. · 2010 · Human molecular genetics · DOI

Full title: Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Year: 2010

Venue: Human molecular genetics

DOI: https://doi.org/10.1093/hmg/ddq253

Paper Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice.

Yang, Dun-Sheng; Stavrides, Philip; Kumar, Asok et al. · 2017 · Human molecular genetics · DOI

Full title: Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice.

Authors: Yang, Dun-Sheng; Stavrides, Philip; Kumar, Asok; Jiang, Ying; Mohan, Panaiyur S; Ohno, Masuo; Dobrenis, Kostantin; Davidson, Cristin D; Saito, Mitsuo; Pawlik, Monika; Huo, Chunfeng; Walkley, Steven U; Nixon, Ralph A

Year: 2017

Venue: Human molecular genetics

DOI: https://doi.org/10.1093/hmg/ddx001

Paper Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

Pistollato, Francesca; Cano, Sandra; Elío, Iñaki et al. · 2016 · Nutrition Reviews · DOI

Full title: Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

Authors: Pistollato, Francesca; Cano, Sandra; Elío, Iñaki; Vergara, Manuel Masias; Giampieri, Francesca; Battino, Maurizio

Year: 2016

Venue: Nutrition Reviews

DOI: https://doi.org/10.1093/nutrit/nuw023

Paper Metformin promotes angiogenesis by enhancing VEGFa secretion by adipose-derived stem cells via the autophagy pathway.

Tao, Zihan; Liu, Lei; Wu, Minliang et al. · 2023 · Regenerative biomaterials · DOI

Full title: Metformin promotes angiogenesis by enhancing VEGFa secretion by adipose-derived stem cells via the autophagy pathway.

Authors: Tao, Zihan; Liu, Lei; Wu, Minliang; Wang, Qianqian; Wang, Yuchong; Xiong, Jiachao; Xue, Chunyu

Year: 2023

Venue: Regenerative biomaterials

DOI: https://doi.org/10.1093/rb/rbad043

Paper Melatonin pretreatment alleviates renal ischemia-reperfusion injury by promoting autophagic flux via TLR4/MyD88/MEK/ERK/mTORC1 signaling.

Yang, Jinghui; Liu, Hao; Han, Shu et al. · 2020 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · DOI

Full title: Melatonin pretreatment alleviates renal ischemia-reperfusion injury by promoting autophagic flux via TLR4/MyD88/MEK/ERK/mTORC1 signaling.

Authors: Yang, Jinghui; Liu, Hao; Han, Shu; Fu, Zhiren; Wang, Jiyuan; Chen, Yu; Wang, Liming

Year: 2020

Venue: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

DOI: https://doi.org/10.1096/fj.202001252R

Paper Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.

Bao, Hui; Zhang, Qianyun; Liu, Xinying et al. · 2019 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · DOI

Full title: Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.

Authors: Bao, Hui; Zhang, Qianyun; Liu, Xinying; Song, Yaxiang; Li, Xinhua; Wang, Zhen; Li, Changbin; Peng, Ai; Gong, Rujun

Year: 2019

Venue: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

DOI: https://doi.org/10.1096/fj.201901712R

Paper Nobiletin-mediated autophagy mitigates nanoplastic-induced toxicity in human intestinal Caco-2 cells.

Yu, Junho; Yoon, Ji-Hwan; Park, Miey et al. · 2025 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · DOI

Full title: Nobiletin-mediated autophagy mitigates nanoplastic-induced toxicity in human intestinal Caco-2 cells.

Authors: Yu, Junho; Yoon, Ji-Hwan; Park, Miey; Lee, Hae-Jeung

Year: 2025

Venue: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

DOI: https://doi.org/10.1096/fj.202402761R

Paper The Effects of Metformin on Weight Loss, Cardiovascular Health, and Longevity.

Pillai, Ashwin A; Melo, Lara; Frishman, William H et al. · 2024 · Cardiology in review · DOI

Full title: The Effects of Metformin on Weight Loss, Cardiovascular Health, and Longevity.

Authors: Pillai, Ashwin A; Melo, Lara; Frishman, William H; Aronow, Wilbert S

Year: 2024

Venue: Cardiology in review

DOI: https://doi.org/10.1097/CRD.0000000000000832

Paper Mood-stabilizing effects of rapamycin and its analog temsirolimus: relevance to autophagy.

Kara, Nirit Z; Flaisher-Grinberg, Shlomit; Anderson, Grant W et al. · 2018 · Behavioural pharmacology · DOI

Full title: Mood-stabilizing effects of rapamycin and its analog temsirolimus: relevance to autophagy.

Authors: Kara, Nirit Z; Flaisher-Grinberg, Shlomit; Anderson, Grant W; Agam, Galila; Einat, Haim

Year: 2018

Venue: Behavioural pharmacology

DOI: https://doi.org/10.1097/FBP.0000000000000334

Paper Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial.

Chen, Po-Chih; Hsieh, Yi-Chen; Huang, Chi-Chen et al. · 2020 · Medicine · DOI

Full title: Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial.

Authors: Chen, Po-Chih; Hsieh, Yi-Chen; Huang, Chi-Chen; Hu, Chaur-Jong

Year: 2020

Venue: Medicine

DOI: https://doi.org/10.1097/MD.0000000000020423

Paper Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.

Li, Mozi; Zhu, Lin; Xu, Yifan et al. · 2025 · The Journal of craniofacial surgery · DOI

Full title: Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.

Authors: Li, Mozi; Zhu, Lin; Xu, Yifan; Han, Zhengxue

Year: 2025

Venue: The Journal of craniofacial surgery

DOI: https://doi.org/10.1097/SCS.0000000000011273

Paper C1q/TNF-Related Protein 9 Inhibits THP-1 Macrophage Foam Cell Formation by Enhancing Autophagy.

Zhang, Lu; Liu, Qi; Zhang, Hui et al. · 2018 · Journal of cardiovascular pharmacology · DOI

Full title: C1q/TNF-Related Protein 9 Inhibits THP-1 Macrophage Foam Cell Formation by Enhancing Autophagy.

Authors: Zhang, Lu; Liu, Qi; Zhang, Hui; Wang, Xue-Dong; Chen, Shu-Yuan; Yang, Yang; Lv, Hang; Hou, Jing-Bo; Yu, Bo

Year: 2018

Venue: Journal of cardiovascular pharmacology

DOI: https://doi.org/10.1097/FJC.0000000000000612

Paper The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure.

Lu, Xiao-Ting; Liu, Xiao-Qiong; Wang, Bo et al. · 2017 · Psychosomatic medicine · DOI

Full title: The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure.

Authors: Lu, Xiao-Ting; Liu, Xiao-Qiong; Wang, Bo; Sun, Yuan-Yuan; Yang, Rui-Xue; Xing, Yi-Fan; Sun, Ping; Wang, Ying-Bin; Zhao, Yu-Xia

Year: 2017

Venue: Psychosomatic medicine

DOI: https://doi.org/10.1097/PSY.0000000000000509

Paper Enhancing Autophagy Protects Against Sepsis-Induced Neuromuscular Dysfunction Associated with Qualitative Changes to Acetylcholine Receptors.

Chen, Jingyuan; Min, Su; Xie, Fei et al. · 2019 · Shock (Augusta, Ga.) · DOI

Full title: Enhancing Autophagy Protects Against Sepsis-Induced Neuromuscular Dysfunction Associated with Qualitative Changes to Acetylcholine Receptors.

Authors: Chen, Jingyuan; Min, Su; Xie, Fei; Yang, Jun; Wang, Xin

Year: 2019

Venue: Shock (Augusta, Ga.)

DOI: https://doi.org/10.1097/SHK.0000000000001189

Paper Autophagy controls mesenchymal stem cell properties and senescence during bone aging.

Ma, Yang; Qi, Meng; An, Ying et al. · 2018 · Aging cell · DOI

Full title: Autophagy controls mesenchymal stem cell properties and senescence during bone aging.

Authors: Ma, Yang; Qi, Meng; An, Ying; Zhang, Liqiang; Yang, Rui; Doro, Daniel H; Liu, Wenjia; Jin, Yan

Year: 2018

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12709

Paper Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.

Ji, Juan; Xue, Teng-Fei; Guo, Xu-Dong et al. · 2018 · Aging cell · DOI

Full title: Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.

Authors: Ji, Juan; Xue, Teng-Fei; Guo, Xu-Dong; Yang, Jin; Guo, Ruo-Bing; Wang, Juan; Huang, Ji-Ye; Zhao, Xiao-Jie; Sun, Xiu-Lan

Year: 2018

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12774

Paper Interventions to Slow Aging in Humans: Are We Ready?

Longo, Valter D.; Antebi, Adam; Bartke, Andrzej et al. · 2015 · Aging Cell · DOI

Full title: Interventions to Slow Aging in Humans: Are We Ready?

Authors: Longo, Valter D.; Antebi, Adam; Bartke, Andrzej; Barzilai, Nir; Brown‐Borg, Holly M.; Caruso, Calogero; Curiel, Tyler J.; Cabo, Rafael de; Franceschi, Claudio; Gems, David; Ingram, Donald K.; Johnson, Thomas E.; Kennedy, Brian K.; Kenyon, Cynthia; Klein, Samuel; Kopchick, John J.; Lepperdinger, Günter; Madeo, Frank; Mirisola, Mario G.; Mitchell, James R.; Passarino, Giuseppe; Rudolph, K. Lenhard; Sedivy, John M.; Shadel, Gerald S.; Sinclair, David; Spindler, Stephen R.; Suh, Yousin; Vijg, Jan; Vinciguerra, Manlio; Fontana, Luigi

Year: 2015

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12338

Paper Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.

Mao, Kanmin; Chen, Jialong; Yu, Honglin et al. · 2020 · Aging cell · DOI

Full title: Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.

Authors: Mao, Kanmin; Chen, Jialong; Yu, Honglin; Li, Huihui; Ren, Yixian; Wu, Xian; Wen, Yue; Zou, Fei; Li, Wenjun

Year: 2020

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13163

Paper Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.

Wang, Ping; Li, Chun Guang; Zhou, Xian et al. · 2022 · Clinical and experimental pharmacology & physiology · DOI

Full title: Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.

Authors: Wang, Ping; Li, Chun Guang; Zhou, Xian; Ding, Shuzhe

Year: 2022

Venue: Clinical and experimental pharmacology & physiology

DOI: https://doi.org/10.1111/1440-1681.13600

Paper Recent developments of HDAC inhibitors: Emerging indications and novel molecules

Bondarev, Andrey D.; Attwood, Misty M.; Jönsson, Jörgen et al. · 2021 · British Journal of Clinical Pharmacology · DOI

Full title: Recent developments of HDAC inhibitors: Emerging indications and novel molecules

Authors: Bondarev, Andrey D.; Attwood, Misty M.; Jönsson, Jörgen; Chubarev, Vladimir N.; Tarasov, Vadim V.; Schiöth, Helgi B.

Year: 2021

Venue: British Journal of Clinical Pharmacology

DOI: https://doi.org/10.1111/bcp.14889

Paper Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species

Parkhitko, Andrey A.; Jouandin, Patrick; Mohr, Stephanie E. et al. · 2019 · Aging Cell · DOI

Full title: Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species

Authors: Parkhitko, Andrey A.; Jouandin, Patrick; Mohr, Stephanie E.; Perrimon, Norbert

Year: 2019

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13034

Paper AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease.

Sun, Fengjiao; Wang, Jiangong; Meng, Lingbin et al. · 2024 · British journal of pharmacology · DOI

Full title: AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease.

Authors: Sun, Fengjiao; Wang, Jiangong; Meng, Lingbin; Zhou, Zhenyu; Xu, Yong; Yang, Meizi; Li, Yixin; Jiang, Tianrui; Liu, Bin; Yan, Haijing

Year: 2024

Venue: British journal of pharmacology

DOI: https://doi.org/10.1111/bph.16400

Paper Clemastine attenuates subarachnoid haemorrhage pathology in a mouse model via Nrf2/SQSTM1-mediated autophagy.

Zou, Yan; Tao, Zhen'xing; Li, Peng'peng et al. · 2025 · British journal of pharmacology · DOI

Full title: Clemastine attenuates subarachnoid haemorrhage pathology in a mouse model via Nrf2/SQSTM1-mediated autophagy.

Authors: Zou, Yan; Tao, Zhen'xing; Li, Peng'peng; Yang, Jie'qiong; Xu, Qin'yi; Xu, Xing; Miao, Zeng'li; Zhao, Xu'dong

Year: 2025

Venue: British journal of pharmacology

DOI: https://doi.org/10.1111/bph.17465

Paper Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation-induced synaptic damage and cognitive dysfunction via autophagy enhancement.

Zhang, Tao; Tian, Yuan; Zheng, Xiaoqing et al. · 2024 · CNS neuroscience & therapeutics · DOI

Full title: Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation-induced synaptic damage and cognitive dysfunction via autophagy enhancement.

Authors: Zhang, Tao; Tian, Yuan; Zheng, Xiaoqing; Li, Ruomeng; Hu, Li; Shui, Xindong; Mei, Yingxue; Wang, Quling; Zhang, Mi; Zheng, Xiuzhi; Wang, Long; Chen, Dongmei; Tao, Wucheng; Lee, Tae Ho

Year: 2024

Venue: CNS neuroscience & therapeutics

DOI: https://doi.org/10.1111/cns.14432

Paper Stabilisation of PRCP by deubiquitinase-targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy.

Zhou, Fangchao; Xia, Jun; Liu, Yingjuan et al. · 2025 · British journal of pharmacology · DOI

Full title: Stabilisation of PRCP by deubiquitinase-targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy.

Authors: Zhou, Fangchao; Xia, Jun; Liu, Yingjuan; He, Wenqi; Zhang, Hongyuan; Keavney, Bernard D; Zi, Min; Nguyen, Binh Y; Mohamed, Tamer M A; Miller, Jessica M; Abouleisa, Riham R E; Hille, Susanne S; Cartwright, Elizabeth J; Müller, Oliver J; Xu, Honglin; Butterworth, Sam; Wang, Xin

Year: 2025

Venue: British journal of pharmacology

DOI: https://doi.org/10.1111/bph.70094

Paper Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.

Yuan, Fanen; Zhang, Si; Sun, Qian et al. · 2022 · CNS neuroscience & therapeutics · DOI

Full title: Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.

Authors: Yuan, Fanen; Zhang, Si; Sun, Qian; Ye, Liguo; Xu, Yang; Xu, Zhou; Deng, Gang; Zhang, Shenqi; Liu, Baohui; Chen, Qianxue

Year: 2022

Venue: CNS neuroscience & therapeutics

DOI: https://doi.org/10.1111/cns.13821

Paper Inhibition of Salt-Inducible Kinase 2 Protects Motor Neurons From Degeneration in ALS by Activating Autophagic Flux and Enhancing mTORC1 Activity.

Liang, Weiwei; Zhang, Chunting; Wang, Di et al. · 2025 · CNS neuroscience & therapeutics · DOI

Full title: Inhibition of Salt-Inducible Kinase 2 Protects Motor Neurons From Degeneration in ALS by Activating Autophagic Flux and Enhancing mTORC1 Activity.

Authors: Liang, Weiwei; Zhang, Chunting; Wang, Di; Su, Xiaoli; Tan, Xingli; Yang, Yueqing; Cong, Chaohua; Wang, Ying; Huo, Di; Wang, Hongyong; Wang, Shuyu; Wang, Xudong; Feng, Honglin

Year: 2025

Venue: CNS neuroscience & therapeutics

DOI: https://doi.org/10.1111/cns.70341

Paper BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

Shi, Ruo‐Yang; Zhu, Shenghua; Li, Victor et al. · 2014 · CNS Neuroscience & Therapeutics · DOI

Full title: BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

Authors: Shi, Ruo‐Yang; Zhu, Shenghua; Li, Victor; Gibson, Spencer B.; Xu, Xingshun; Kong, Jiming

Year: 2014

Venue: CNS Neuroscience & Therapeutics

DOI: https://doi.org/10.1111/cns.12325

Paper The Role of Tau in Alzheimer's Disease and Related Disorders

Medeiros, Rodrigo; Baglietto‐Vargas, David; LaFerla, Frank M. · 2010 · CNS Neuroscience & Therapeutics · DOI

Full title: The Role of Tau in Alzheimer's Disease and Related Disorders

Authors: Medeiros, Rodrigo; Baglietto‐Vargas, David; LaFerla, Frank M.

Year: 2010

Venue: CNS Neuroscience & Therapeutics

DOI: https://doi.org/10.1111/j.1755-5949.2010.00177.x

Paper Oxidative stress and aberrant signaling in aging and cognitive decline

Dröge, Wulf; Schipper, Hyman M. · 2007 · Aging Cell · DOI

Full title: Oxidative stress and aberrant signaling in aging and cognitive decline

Authors: Dröge, Wulf; Schipper, Hyman M.

Year: 2007

Venue: Aging Cell

DOI: https://doi.org/10.1111/j.1474-9726.2007.00294.x

Paper Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

Kleinnijenhuis, Johanneke; Oosting, Marije; Plantinga, Theo S et al. · 2011 · Immunology · DOI

Full title: Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

Authors: Kleinnijenhuis, Johanneke; Oosting, Marije; Plantinga, Theo S; van der Meer, Jos W M; Joosten, Leo A B; Crevel, Reinout V; Netea, Mihai G

Year: 2011

Venue: Immunology

DOI: https://doi.org/10.1111/j.1365-2567.2011.03494.x

Paper STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy.

McCormick, J; Suleman, N; Scarabelli, T M et al. · 2012 · Journal of cellular and molecular medicine · DOI

Full title: STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy.

Authors: McCormick, J; Suleman, N; Scarabelli, T M; Knight, R A; Latchman, D S; Stephanou, A

Year: 2012

Venue: Journal of cellular and molecular medicine

DOI: https://doi.org/10.1111/j.1582-4934.2011.01323.x

Paper Signaling pathways and defense mechanisms of ferroptosis

Liu, Jiao; Kang, Rui; Tang, Daolin · 2021 · FEBS Journal · DOI

Full title: Signaling pathways and defense mechanisms of ferroptosis

Authors: Liu, Jiao; Kang, Rui; Tang, Daolin

Year: 2021

Venue: FEBS Journal

DOI: https://doi.org/10.1111/febs.16059

Paper Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.

Zhao, Ting; Hong, Yan; Li, Shihua et al. · 2016 · The Journal of neuroscience : the official journal of the Society for Neuroscience · DOI

Full title: Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.

Authors: Zhao, Ting; Hong, Yan; Li, Shihua; Li, Xiao-Jiang

Year: 2016

Venue: The Journal of neuroscience : the official journal of the Society for Neuroscience

DOI: https://doi.org/10.1523/JNEUROSCI.0806-16.2016

Paper Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

Xiao, Qingli; Yan, Ping; Ma, Xiucui et al. · 2015 · Journal of Neuroscience · DOI

Full title: Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

Authors: Xiao, Qingli; Yan, Ping; Ma, Xiucui; Liu, Haiyan; Perez, Ronaldo; Zhu, Alec; Gonzales, Ernesto R.; Tripoli, Danielle L.; Czerniewski, Leah; Ballabio, Andrea; Cirrito, John R.; Diwan, Abhinav; Lee, Jin‐Moo

Year: 2015

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.0705-15.2015

Paper Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis

Xiao, Qingli; Yan, Ping; Ma, Xiucui et al. · 2014 · Journal of Neuroscience · DOI

Full title: Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis

Authors: Xiao, Qingli; Yan, Ping; Ma, Xiucui; Liu, Haiyan; Perez, Ronaldo; Zhu, Alec; Gonzales, Ernesto R.; Burchett, Jack M.; Schuler, Dorothy R.; Cirrito, John R.; Diwan, Abhinav; Lee, Jin‐Moo

Year: 2014

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.3788-13.2014

Paper Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation

Dompierre, Jim; Godin, Juliette D.; Charrin, Bénédicte C. et al. · 2007 · Journal of Neuroscience · DOI

Full title: Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation

Authors: Dompierre, Jim; Godin, Juliette D.; Charrin, Bénédicte C.; Cordelières, Fabrice P.; King, Stephen J.; Humbert, Sandrine; Saudou, Frédéric

Year: 2007

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.0037-07.2007

Paper G2019S-LRRK2 Expression Augments -Synuclein Sequestration into Inclusions in Neurons

Volpicelli‐Daley, Laura A.; Abdelmotilib, Hisham; Liu, Zhiyong et al. · 2016 · Journal of Neuroscience · DOI

Full title: G2019S-LRRK2 Expression Augments -Synuclein Sequestration into Inclusions in Neurons

Authors: Volpicelli‐Daley, Laura A.; Abdelmotilib, Hisham; Liu, Zhiyong; Stoyka, Lindsay E.; Daher, João Paulo Lima; Milnerwood, Austen J.; Unni, V. K.; Hirst, Warren D.; Yue, Zhenyu; Zhao, Hongfan; Fraser, Kyle; Kennedy, Richard; West, Andrew B.

Year: 2016

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.3642-15.2016

Paper Genetic Reduction of Mammalian Target of Rapamycin Ameliorates Alzheimer's Disease-Like Cognitive and Pathological Deficits by Restoring Hippocampal Gene Expression Signature

Caccamo, Antonella; Pinto, Vito De; Messina, Angela et al. · 2014 · Journal of Neuroscience · DOI

Full title: Genetic Reduction of Mammalian Target of Rapamycin Ameliorates Alzheimer's Disease-Like Cognitive and Pathological Deficits by Restoring Hippocampal Gene Expression Signature

Authors: Caccamo, Antonella; Pinto, Vito De; Messina, Angela; Branca, Caterina; Oddo, Salvatore

Year: 2014

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.0777-14.2014

Paper Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein

Ebrahimi‐Fakhari, Darius; Cantuti‐Castelvetri, Ippolita; Fan, Zhanyun et al. · 2011 · Journal of Neuroscience · DOI

Full title: Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein

Authors: Ebrahimi‐Fakhari, Darius; Cantuti‐Castelvetri, Ippolita; Fan, Zhanyun; Rockenstein, Edward; Masliah, Eliezer; Hyman, Bradley T.; McLean, Pamela J.; Unni, Vivek K.

Year: 2011

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.1560-11.2011

Paper Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

Pimplikar, Sanjay W.; Nixon, Ralph A.; Robakis, Nikolaos K. et al. · 2010 · Journal of Neuroscience · DOI

Full title: Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

Authors: Pimplikar, Sanjay W.; Nixon, Ralph A.; Robakis, Nikolaos K.; Shen, Jie; Tsai, Li-Huei

Year: 2010

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.4305-10.2010

Paper Restoration of Sleep and Circadian Behavior by Autophagy Modulation in Huntington's Disease.

Sharma, Ankit; Narasimha, Kavyashree; Manjithaya, Ravi et al. · 2023 · The Journal of neuroscience : the official journal of the Society for Neuroscience · DOI

Full title: Restoration of Sleep and Circadian Behavior by Autophagy Modulation in Huntington's Disease.

Authors: Sharma, Ankit; Narasimha, Kavyashree; Manjithaya, Ravi; Sheeba, Vasu

Year: 2023

Venue: The Journal of neuroscience : the official journal of the Society for Neuroscience

DOI: https://doi.org/10.1523/JNEUROSCI.1894-22.2023

Paper Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice.

Rangaraju, Sunitha; Verrier, Jonathan D; Madorsky, Irina et al. · 2010 · The Journal of neuroscience : the official journal of the Society for Neuroscience · DOI

Full title: Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice.

Authors: Rangaraju, Sunitha; Verrier, Jonathan D; Madorsky, Irina; Nicks, Jessica; Dunn, William A; Notterpek, Lucia

Year: 2010

Venue: The Journal of neuroscience : the official journal of the Society for Neuroscience

DOI: https://doi.org/10.1523/JNEUROSCI.1356-10.2010

Paper Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions.

Hu, Wenjing; Zhu, Huijuan; Gong, Fengying · 2025 · Endocrine connections · DOI

Full title: Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions.

Authors: Hu, Wenjing; Zhu, Huijuan; Gong, Fengying

Year: 2025

Venue: Endocrine connections

DOI: https://doi.org/10.1530/EC-25-0521

Paper Autophagy-Induced Drug Resistance in Liver Cancer.

Vempati, Rahul Kumar; Malla, Rama Rao · 2020 · Critical reviews in oncogenesis · DOI

Full title: Autophagy-Induced Drug Resistance in Liver Cancer.

Authors: Vempati, Rahul Kumar; Malla, Rama Rao

Year: 2020

Venue: Critical reviews in oncogenesis

DOI: https://doi.org/10.1615/CritRevOncog.2020034969

Paper Drosophila as an In Vivo Model for Human Neurodegenerative Disease

McGurk, Leeanne; Berson, Amit; Bonini, Nancy M. · 2015 · Genetics · DOI

Full title: Drosophila as an In Vivo Model for Human Neurodegenerative Disease

Authors: McGurk, Leeanne; Berson, Amit; Bonini, Nancy M.

Year: 2015

Venue: Genetics

DOI: https://doi.org/10.1534/genetics.115.179457

Paper Health benefits of resveratrol administration

Galiniak, Sabina; Aebisher, David; Bartusik‐Aebisher, Dorota · 2019 · Acta Biochimica Polonica · DOI

Full title: Health benefits of resveratrol administration

Authors: Galiniak, Sabina; Aebisher, David; Bartusik‐Aebisher, Dorota

Year: 2019

Venue: Acta Biochimica Polonica

DOI: https://doi.org/10.18388/abp.2018_2749

Paper Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1.

Ma, Chaoting; Zhang, Dandan; Ma, Qiuyan et al. · 2021 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · DOI

Full title: Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1.

Authors: Ma, Chaoting; Zhang, Dandan; Ma, Qiuyan; Liu, Yu; Yang, Yingxin

Year: 2021

Venue: Advances in clinical and experimental medicine : official organ Wroclaw Medical University

DOI: https://doi.org/10.17219/acem/133493

Paper [Antidepressants as additional drugs for human brain gliomas].

Revishchin, A V; Pavlova, G V · 2024 · Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko · DOI

Full title: [Antidepressants as additional drugs for human brain gliomas].

Authors: Revishchin, A V; Pavlova, G V

Year: 2024

Venue: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko

DOI: https://doi.org/10.17116/neiro20248806197

Paper Enhancing autophagy protects platelets in immune thrombocytopenia patients.

Wang, Chun-Yan; Ma, Sai; Bi, Shao-Jie et al. · 2019 · Annals of translational medicine · DOI

Full title: Enhancing autophagy protects platelets in immune thrombocytopenia patients.

Authors: Wang, Chun-Yan; Ma, Sai; Bi, Shao-Jie; Su, Le; Huang, Shu-Ya; Miao, Jun-Ying; Ma, Chun-Hong; Gao, Cheng-Jiang; Hou, Ming; Peng, Jun

Year: 2019

Venue: Annals of translational medicine

DOI: https://doi.org/10.21037/atm.2019.03.04

Paper Effect of c-Jun NH₂-terminal kinase-mediated p53 expression on neuron autophagy following traumatic brain injury in rats.

Hong, Ming-Yan; Gao, Jun-Ling; Cui, Jian-Zhong et al. · 2012 · Chinese medical journal

Full title: Effect of c-Jun NH₂-terminal kinase-mediated p53 expression on neuron autophagy following traumatic brain injury in rats.

Authors: Hong, Ming-Yan; Gao, Jun-Ling; Cui, Jian-Zhong; Wang, Kai-Jie; Tian, Yan-Xia; Li, Ran; Wang, Hai-Tao; Wang, Huan

Year: 2012

Venue: Chinese medical journal

Paper Decreased expression of adenosine receptor 2B confers cardiac protection against ischemia via restoring autophagic flux.

Zhan, Enbo; Cao, Wei; Fan, Xiaoying et al. · 2020 · American journal of translational research

Full title: Decreased expression of adenosine receptor 2B confers cardiac protection against ischemia via restoring autophagic flux.

Authors: Zhan, Enbo; Cao, Wei; Fan, Xiaoying; Zhang, Ruoxi; Du, Hongwei; Xu, Yousheng; Li, Lili; Dong, Nana; Li, Shaojun

Year: 2020

Venue: American journal of translational research

Paper GOLPH3 promotes glioma progression by enhancing PHB2-mediated autophagy.

Wang, Kai; Qi, Yanhua; Wang, Xu et al. · 2021 · American journal of cancer research

Full title: GOLPH3 promotes glioma progression by enhancing PHB2-mediated autophagy.

Authors: Wang, Kai; Qi, Yanhua; Wang, Xu; Liu, Yushuai; Zhao, Min; Zhou, Ding; Zhang, Yu; Wang, Yan; Yu, Rutong; Zhou, Xiuping

Year: 2021

Venue: American journal of cancer research

Paper The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis.

Chen, Yanchun; Liu, Huancai; Guan, Yingjun et al. · 2015 · American journal of translational research

Full title: The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis.

Authors: Chen, Yanchun; Liu, Huancai; Guan, Yingjun; Wang, Qiaozhen; Zhou, Fenghua; Jie, Linlin; Ju, Jie; Pu, Leidong; Du, Hongmei; Wang, Xin

Year: 2015

Venue: American journal of translational research

Paper Osteopontin-integrin signaling positively regulates neuroplasticity through enhancing neural autophagy in the peri-infarct area after ischemic stroke.

Liao, Haikang; Zou, Zhenyou; Liu, Weiqin et al. · 2022 · American journal of translational research

Full title: Osteopontin-integrin signaling positively regulates neuroplasticity through enhancing neural autophagy in the peri-infarct area after ischemic stroke.

Authors: Liao, Haikang; Zou, Zhenyou; Liu, Weiqin; Guo, Xuefeng; Xie, Jinlu; Li, Liangxian; Li, Xia; Gan, Xinying; Huang, Xiansheng; Liu, Juxia; Li, Wenyang; Zeng, Hongji; Chen, Zheng; Jiang, Qiuhua; Yao, Hua

Year: 2022

Venue: American journal of translational research

Paper Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury in vitro.

Thapalia, Bisharad Anil; Zhou, Zhen; Lin, Xianhe · 2016 · American journal of translational research

Full title: Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury in vitro.

Authors: Thapalia, Bisharad Anil; Zhou, Zhen; Lin, Xianhe

Year: 2016

Venue: American journal of translational research

Paper Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury.

Gao, Yongyue; Zhuang, Zong; Gao, Shanting et al. · 2017 · American journal of translational research

Full title: Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury.

Authors: Gao, Yongyue; Zhuang, Zong; Gao, Shanting; Li, Xiang; Zhang, Zihuan; Ye, Zhennan; Li, Liwen; Tang, Chao; Zhou, Mengliang; Han, Xiao; Li, Jie

Year: 2017

Venue: American journal of translational research

Paper Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells.

Hu, Guanzheng; Gong, Xiaoli; Wang, Le et al. · 2017 · Molecular neurobiology · DOI

Full title: Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells.

Authors: Hu, Guanzheng; Gong, Xiaoli; Wang, Le; Liu, Mengru; Liu, Yang; Fu, Xia; Wang, Wei; Zhang, Ting; Wang, Xiaomin

Year: 2017

Venue: Molecular neurobiology

DOI: https://doi.org/10.1007/s12035-016-9808-3

Paper CORM-3 mitigates osteoarthritis by anti-inflammation and enhancing autophagy via inhibiting MAPK and mTOR pathways.

Li, Jianwen; Zeng, Yunqian; Wang, Shiheng et al. · 2025 · International immunopharmacology · DOI

Full title: CORM-3 mitigates osteoarthritis by anti-inflammation and enhancing autophagy via inhibiting MAPK and mTOR pathways.

Authors: Li, Jianwen; Zeng, Yunqian; Wang, Shiheng; Chen, Xin; Huang, Hui; Gan, Xin; Kang, Hao

Year: 2025

Venue: International immunopharmacology

DOI: https://doi.org/10.1016/j.intimp.2025.115296

Paper Lithium and autophagy.

Motoi, Yumiko; Shimada, Kohei; Ishiguro, Koichi et al. · 2014 · ACS chemical neuroscience · DOI

Full title: Lithium and autophagy.

Authors: Motoi, Yumiko; Shimada, Kohei; Ishiguro, Koichi; Hattori, Nobutaka

Year: 2014

Venue: ACS chemical neuroscience

DOI: https://doi.org/10.1021/cn500056q

Paper Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease

Cabezas-Opazo, Fabian; Vergara-Pulgar, Katiana; J., Maria Jose Perez et al. · 2015 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease

Authors: Cabezas-Opazo, Fabian; Vergara-Pulgar, Katiana; J., Maria Jose Perez; Jara, Claudia; Osorio‐Fuentealba, Cesár; Quintanilla, Rodrigo A.

Year: 2015

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2015/509654

Thesis Dissecting the contribution of dipeptide repeats to the toxicity in C9orf72 iPSC-derived neurons from ALS/FTD patients

Barbagallo, P · 2021 · University of Oxford - ORA · DOI

Full title: Dissecting the contribution of dipeptide repeats to the toxicity in C9orf72 iPSC-derived neurons from ALS/FTD patients

Authors: Barbagallo, P

Year: 2021

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:998f2cb2-f708-4d5e-850f-61bc1f87d870

Thesis Preclinical models for Alzheimer's Disease:Past, present, and future approaches

Akhtar, Ansab; Gupta, Shraddha M.; Dwivedi, Shubham et al. · 2022 · Charles Sturt University - Research Output · DOI

Full title: Preclinical models for Alzheimer's Disease:Past, present, and future approaches

Authors: Akhtar, Ansab; Gupta, Shraddha M.; Dwivedi, Shubham; Kumar, Devendra; Shaikh, Mohd Farooq; id_orcid 0000-0001-9865-6224; Negi, Arvind

Year: 2022

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/63bf05b2-6128-4541-a224-6a6ff92d233d

Thesis Mapping networks of alpha-Synuclein proteostasis in cellular models of Parkinson's disease pathology

Lewin, R · 2020 · University of Oxford - ORA · DOI

Full title: Mapping networks of alpha-Synuclein proteostasis in cellular models of Parkinson's disease pathology

Authors: Lewin, R

Year: 2020

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:e810b4c4-4a4e-4843-b6f1-6813dcabbe20

Thesis Sestrin-mediated inhibition of stress-induced intervertebral disc degradation through enhancement of autophagy

Tu, Ji; Li, Wentian; Li, Shuai et al. · 2018 · Charles Sturt University - Research Output · DOI

Full title: Sestrin-mediated inhibition of stress-induced intervertebral disc degradation through enhancement of autophagy

Authors: Tu, Ji; Li, Wentian; Li, Shuai; Liu, Wei; Zhang, Yukun; Wu, Xinghuo; Luo, Rongjin; Hua, Wenbin; Wang, Kun; Song, Yu; Kang, Liang; Yang, Wen; Yang, Shuhua; Yang, Cao

Year: 2018

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/775b73b7-4cd3-4074-9740-8e2cc34baae9

Thesis The proteinopenia hypothesis:Loss of Aβ 42 and the onset of Alzheimer's Disease

Espay, Alberto J.; Herrup, Karl; Kepp, Kasper P. et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: The proteinopenia hypothesis:Loss of Aβ 42 and the onset of Alzheimer's Disease

Authors: Espay, Alberto J.; Herrup, Karl; Kepp, Kasper P.; id_orcid 0000-0002-6754-7348; Daly, Timothy

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/6f2dd48d-0092-425e-a375-d9505a5236f8

Thesis Detecting mitophagy in mitochondrial disease: towards a new type of therapy

Dombi, E · 2019 · University of Oxford - ORA · DOI

Full title: Detecting mitophagy in mitochondrial disease: towards a new type of therapy

Authors: Dombi, E

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:d13f5226-f1e3-4097-baa1-6274213c1253

Thesis The effects of mTOR inhibition in ischemic stroke

Schneider, AM · 2022 · University of Oxford - ORA · DOI

Full title: The effects of mTOR inhibition in ischemic stroke

Authors: Schneider, AM

Year: 2022

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:eed92456-d839-4e5c-9d70-f27f5a3d635f

Thesis Lysosomal dysfunction and glycosphingolipid dysregulation in rare and common neurodegenerative diseases

Huebecker, M · 2019 · University of Oxford - ORA · DOI

Full title: Lysosomal dysfunction and glycosphingolipid dysregulation in rare and common neurodegenerative diseases

Authors: Huebecker, M

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:fa971c3c-9d2e-4a42-829a-3e724336c6ec

Thesis Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases:A molecular crosstalk

Kaviyarasan, Shobana; Chung Sia, Edmund Lee; Retinasamy, Thaarvena et al. · 2022 · Charles Sturt University - Research Output · DOI

Full title: Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases:A molecular crosstalk

Authors: Kaviyarasan, Shobana; Chung Sia, Edmund Lee; Retinasamy, Thaarvena; Arulsamy, Alina; Shaikh, Mohd Farooq; id_orcid 0000-0001-9865-6224

Year: 2022

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/876bb5c1-9dde-477e-b4b4-c7176d0263b1

Thesis Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

Eriksen, Anne Zebitz; Eliasen, Rasmus; Oswald, Julia et al. · 2018 · Technical University of Denmark (DTU) · DOI

Full title: Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

Authors: Eriksen, Anne Zebitz; Eliasen, Rasmus; Oswald, Julia; Kempen, Paul J.; id_orcid 0000-0003-2179-2257; Melander, Fredrik; id_orcid 0000-0002-3670-6633; Andresen, Thomas Lars; id_orcid 0000-0002-1048-127X; Young, Michael; Baranov, Petr; Urquhart, Andrew J.; id_orcid 0000-0002-5322-0002

Year: 2018

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a0147284-c7b8-4d29-a73d-abdbd7b2f3e6

Thesis Passive Alzheimer's immunotherapy:A promising or uncertain option?

Høilund-Carlsen, Poul F.; Revheim, Mona Elisabeth; Costa, Tommaso et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Passive Alzheimer's immunotherapy:A promising or uncertain option?

Authors: Høilund-Carlsen, Poul F.; Revheim, Mona Elisabeth; Costa, Tommaso; Alavi, Abass; Kepp, Kasper P.; id_orcid 0000-0002-6754-7348; Sensi, Stefano L.; Perry, George; Robakis, Nikolaos K.; Barrio, Jorge R.; Vissel, Bryce

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/49af8024-bae9-448c-b1b4-c0a9b08ae75a

Thesis Preclinical models for Alzheimer's Disease:Past, present, and future approaches

Akhtar, Ansab; Gupta, Shraddha M.; Dwivedi, Shubham et al. · 2022 · Charles Sturt University - Research Output · DOI

Full title: Preclinical models for Alzheimer's Disease:Past, present, and future approaches

Authors: Akhtar, Ansab; Gupta, Shraddha M.; Dwivedi, Shubham; Kumar, Devendra; Shaikh, Mohd Farooq; id_orcid 0000-0001-9865-6224; Negi, Arvind

Year: 2022

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/63bf05b2-6128-4541-a224-6a6ff92d233d

Thesis NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-1 condensation with p62

Furthmann, Nikolas; Angersbach, Lena; Bader, Verian et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-1 condensation with p62

Authors: Furthmann, Nikolas; Angersbach, Lena; Bader, Verian; Blusch, Alina; Goel, Simran; Sánchez-Vicente, Ana; Krause, Laura J.; Grover, Prerna; Trinkhaus, Victoria A.; van Well, Eva M.; Jaugstetter, Maximilian; Tschulik, Kristina; Damgaard, Rune Busk; id_orcid 0000-0002-1709-6534; Saft, Carsten; Ellrichmann , Gisa; Gold, Ralf; Koch, Arend; Englert, Benjamin; Glatzel, Markus; Hartl, F. Ulrich; Nakamura, Ken; Christine, Chadwick W.; Huang, Eric J.; Tatzelt, Jörg; Winklhofer, Konstanze F.

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d405aabc-7e7b-47c1-ac73-5b3130b35345

Thesis Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin

Kaiser, Nadine; Corkery, Dale; Wu, Yaowen et al. · 2019 · Technical University of Denmark (DTU) · DOI

Full title: Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin

Authors: Kaiser, Nadine; Corkery, Dale; Wu, Yaowen; Laraia, Luca; id_orcid 0000-0001-6692-3412; Waldmann, Herbert

Year: 2019

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/1cbc9466-13ee-49e1-8da8-6e570a73b5e7

Thesis Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Matrone, Carmela; Dzamko, Nicolas; Madsen, Peder et al. · 2016 · Technical University of Denmark (DTU) · DOI

Full title: Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Authors: Matrone, Carmela; Dzamko, Nicolas; Madsen, Peder; Nyegaard, Mette; Pohlmann, Regina; Søndergaard, Rikke Vicki; Lassen, Louise B.; Andresen, Thomas Lars; id_orcid 0000-0002-1048-127X; Halliday, Glenda M.; Jensen, Poul Henning; Nielsen, Morten S.

Year: 2016

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/909461e1-fae9-46bd-9b26-bee8d9049e2f

Thesis Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds

Borland, Helena; Vilhardt, Frederik · 2017 · University of Copenhagen · DOI

Full title: Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds

Authors: Borland, Helena; Vilhardt, Frederik

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/afc8d794-3988-4a8d-9c7f-a61378401dd8

Thesis The proteinopenia hypothesis:Loss of Aβ 42 and the onset of Alzheimer's Disease

Espay, Alberto J.; Herrup, Karl; Kepp, Kasper P. et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: The proteinopenia hypothesis:Loss of Aβ 42 and the onset of Alzheimer's Disease

Authors: Espay, Alberto J.; Herrup, Karl; Kepp, Kasper P.; id_orcid 0000-0002-6754-7348; Daly, Timothy

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/6f2dd48d-0092-425e-a375-d9505a5236f8

Thesis Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Matrone, Carmela; Dzamko, Nicolas; Madsen, Peder et al. · 2016 · Technical University of Denmark (DTU) · DOI

Full title: Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Year: 2016

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/909461e1-fae9-46bd-9b26-bee8d9049e2f

Thesis Sestrin-mediated inhibition of stress-induced intervertebral disc degradation through enhancement of autophagy

Tu, Ji; Li, Wentian; Li, Shuai et al. · 2018 · Charles Sturt University - Research Output · DOI

Full title: Sestrin-mediated inhibition of stress-induced intervertebral disc degradation through enhancement of autophagy

Authors: Tu, Ji; Li, Wentian; Li, Shuai; Liu, Wei; Zhang, Yukun; Wu, Xinghuo; Luo, Rongjin; Hua, Wenbin; Wang, Kun; Song, Yu; Kang, Liang; Yang, Wen; Yang, Shuhua; Yang, Cao

Year: 2018

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/775b73b7-4cd3-4074-9740-8e2cc34baae9

Thesis Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

Eriksen, Anne Zebitz; Eliasen, Rasmus; Oswald, Julia et al. · 2018 · Technical University of Denmark (DTU) · DOI

Full title: Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

Year: 2018

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a0147284-c7b8-4d29-a73d-abdbd7b2f3e6

Thesis Emerging neuroprotective effect of metformin in Parkinson's disease:A molecular crosstalk

Paudel, Yam Nath; Angelopoulou, Efthalia; Piperi, Christina et al. · 2020 · Charles Sturt University - Research Output · DOI

Full title: Emerging neuroprotective effect of metformin in Parkinson's disease:A molecular crosstalk

Authors: Paudel, Yam Nath; Angelopoulou, Efthalia; Piperi, Christina; Shaikh, Mohd. Farooq; id_orcid 0000-0001-9865-6224; Othman, Iekhsan

Year: 2020

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/9f17a857-0161-490c-a783-13ec9375c9a0

Thesis Urea and thiourea modified polypropyleneimine dendrimers clear intracellular α-synuclein aggregates in a human cell line

Laumann, Kristoffer; Boas, Ulrik; Larsen, Hjalte Martin et al. · 2015 · Technical University of Denmark (DTU) · DOI

Full title: Urea and thiourea modified polypropyleneimine dendrimers clear intracellular α-synuclein aggregates in a human cell line

Authors: Laumann, Kristoffer; Boas, Ulrik; Larsen, Hjalte Martin; Heegaard, Peter M. H.; id_orcid 0000-0003-4506-4932; Bergström, Ann-Louise

Year: 2015

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/fa8b2bc7-ba11-406c-9079-e07502135dcb

Thesis Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases:A molecular crosstalk

Kaviyarasan, Shobana; Chung Sia, Edmund Lee; Retinasamy, Thaarvena et al. · 2022 · Charles Sturt University - Research Output · DOI

Full title: Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases:A molecular crosstalk

Authors: Kaviyarasan, Shobana; Chung Sia, Edmund Lee; Retinasamy, Thaarvena; Arulsamy, Alina; Shaikh, Mohd Farooq; id_orcid 0000-0001-9865-6224

Year: 2022

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/876bb5c1-9dde-477e-b4b4-c7176d0263b1

Thesis Mitophagy and Neuroprotection

Lou, Guofeng; Palikaras, Konstantinos; Lautrup, Sofie et al. · 2020 · University of Copenhagen · DOI

Full title: Mitophagy and Neuroprotection

Authors: Lou, Guofeng; Palikaras, Konstantinos; Lautrup, Sofie; Scheibye-Knudsen, Morten; Tavernarakis, Nektarios; Fang, Evandro F.

Year: 2020

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/935b40f3-1bca-4510-87c3-1aa52ea78bae

Thesis NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-1 condensation with p62

Furthmann, Nikolas; Angersbach, Lena; Bader, Verian et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-1 condensation with p62

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d405aabc-7e7b-47c1-ac73-5b3130b35345

Thesis Small molecule probes for targeting autophagy

Whitmarsh-Everiss, Thomas Edward; id_orcid 0000-0002-9958-7379; Laraia, Luca et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Small molecule probes for targeting autophagy

Authors: Whitmarsh-Everiss, Thomas Edward; id_orcid 0000-0002-9958-7379; Laraia, Luca; id_orcid 0000-0001-6692-3412

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/fbe37349-2329-4821-8b77-946bfe724ee2

Thesis Late-in-life treadmill training rejuvenates autophagy, protein aggregate clearance, and function in mouse hearts

Cho, Jae Min; Park, Seul-Ki; Ghosh, Rajeshwary et al. · 2022 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Late-in-life treadmill training rejuvenates autophagy, protein aggregate clearance, and function in mouse hearts

Authors: Cho, Jae Min; Park, Seul-Ki; Ghosh, Rajeshwary; Ly, Kellsey; Ramous, Caroline; Thompson, Lauren; Hansen, Michele; Mattera, Maria Sara de Lima Coutinho [UNESP]; Pires, Karla Maria; Ferhat, Maroua; Mookherjee, Sohom; Whitehead, Kevin J.; Carter, Kandis; Buffolo, Márcio; Boudina, Sihem; Symons, J. David

Year: 2022

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1111/acel.13467

Thesis Insights for Alzheimer's disease pharmacotherapy and current clinical trials

Nascimento, A. L.C.S. [UNESP]; Fernandes, R. P.; Carvalho, A. C.S. [UNESP] et al. · 2023 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Insights for Alzheimer's disease pharmacotherapy and current clinical trials

Authors: Nascimento, A. L.C.S. [UNESP]; Fernandes, R. P.; Carvalho, A. C.S. [UNESP]; Frigieri, I. [UNESP]; Alves, R. C. [UNESP]; Chorilli, M. [UNESP]

Year: 2023

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1016/j.neuint.2022.105401

Thesis New treatment strategies for Alzheimer's disease: is there a hope?

Aprahamian, Ivan; Stella, Florindo [UNESP]; Forlenza, Orestes V. · 2014 · Universidade Estadual Paulista (UNESP) · DOI

Full title: New treatment strategies for Alzheimer's disease: is there a hope?

Authors: Aprahamian, Ivan; Stella, Florindo [UNESP]; Forlenza, Orestes V.

Year: 2014

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2013;volume=138;issue=4;spage=449;epage=460;aulast=Aprahamian;type=0

Thesis New treatment strategies for Alzheimer's disease: Is there a hope?

Aprahamian, Ivan; Stella, Florindo [UNESP]; Forlenza, Orestes V. · 2022 · Universidade Estadual Paulista (UNESP) · DOI

Full title: New treatment strategies for Alzheimer's disease: Is there a hope?

Authors: Aprahamian, Ivan; Stella, Florindo [UNESP]; Forlenza, Orestes V.

Year: 2022

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/231308

Thesis Multi-factorial treatment paradigm detection could be the answer to complex diseases: a case study of ALS

Kittel, Tyler Elizabeth · 2020 · Georgia Institute of Technology · DOI

Full title: Multi-factorial treatment paradigm detection could be the answer to complex diseases: a case study of ALS

Authors: Kittel, Tyler Elizabeth

Year: 2020

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/63822

Thesis Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

Park, Jong-Chan; Barahona-Torres, Natalia; Jang, So-Young et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

Authors: Park, Jong-Chan; Barahona-Torres, Natalia; Jang, So-Young; Mok, KinY.; Kim, HaengJun; Han, Sun-Ho; Cho, Kwang-Hyun; Zhou, Xiaopu; Fu, Amy K.Y.; Ip, Nancy Yuk-yu; Seo, Jieun; Choi, Murim; Jeong, Hyobin; Hwang, Daehee; Lee, Dong Young; Byun, Min Soo; Yi, Dahyun; Han, Jong Won; Mook-Jung, Inhee; Hardy, John

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-118243

Thesis Elucidating the Neuroinflammatory Signaling Roles of Heme in Alzheimer's Disease Environments

Sankar, Sitara Bala · 2021 · Georgia Institute of Technology · DOI

Full title: Elucidating the Neuroinflammatory Signaling Roles of Heme in Alzheimer's Disease Environments

Authors: Sankar, Sitara Bala

Year: 2021

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/64557

Thesis Coenzyme Q(10) and its effects in the treatment of neurodegenerative diseases

dos Santos, Graciela Cristina [UNESP]; Greggi Antunes, Lusania Maria; dos Santos, Antonio Cardozo et al. · 2014 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Coenzyme Q(10) and its effects in the treatment of neurodegenerative diseases

Authors: dos Santos, Graciela Cristina [UNESP]; Greggi Antunes, Lusania Maria; dos Santos, Antonio Cardozo; Pires Bianchi, Maria de Lourdes

Year: 2014

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1590/S1984-82502009000400002

Thesis Characterizing Heme Signaling and Bioavailability in Neurodegeneration

Bryant, Mary-Catherine · 2020 · Georgia Institute of Technology · DOI

Full title: Characterizing Heme Signaling and Bioavailability in Neurodegeneration

Authors: Bryant, Mary-Catherine

Year: 2020

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/63842

Thesis ATM loss disrupts the autophagy-lysosomal pathway

Cheng, Aifang; Tse, Kai-Hei; Chow, Hei-Man et al. · 2020 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: ATM loss disrupts the autophagy-lysosomal pathway

Authors: Cheng, Aifang; Tse, Kai-Hei; Chow, Hei-Man; Gan, Yunqiao; Song, Xuan; Ma, Fulin; Qian, Yi Xuan Yvonne; She, Weiyi; Herrup, Karl

Year: 2020

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-104361

Thesis DEVELOPMENT AND CHARACTERIZATION OF VIRAL VECTORS FOR STRESS-DEPENDENT TRANSGENE EXPRESSION IN NEURONS

Santiago-Lopez, Angel J. · 2022 · Georgia Institute of Technology · DOI

Full title: DEVELOPMENT AND CHARACTERIZATION OF VIRAL VECTORS FOR STRESS-DEPENDENT TRANSGENE EXPRESSION IN NEURONS

Authors: Santiago-Lopez, Angel J.

Year: 2022

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/66406

Thesis Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology

Hou, Xu; Watzlawik, Jens O.; Cook, Casey et al. · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology

Authors: Hou, Xu; Watzlawik, Jens O.; Cook, Casey; Liu, Chia-Chen; Kang, Silvia S.; Lin, Wen-Lang; DeTure, Michael; Heckman, Michael G.; Diehl, Nancy N.; Al-Shaikh, Fadi S. Hanna; Walton, Ronald L.; Ross, Owen A.; Melrose, Heather L.; Ertekin-Taner, Nilüfer; Bu, Guojun; Petrucelli, Leonard; Fryer, John D.; Murray, Melissa E.; Dickson, Dennis W.; Fiesel, Fabienne C.; Springer, Wolfdieter

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130472

Thesis The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation

Liao, Yumei; Wang, Jun-Ya; Pan, Yan et al. · 2023 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation

Authors: Liao, Yumei; Wang, Jun-Ya; Pan, Yan; Zou, Xueyi; Wang, Chaoqun; Peng, Yinghui; Ao, Yun-Lin; Lam, Mei Fong; Zhang, Xiaoshen; Zhang, Xiao-Qi; Shi, Lei; Zhang, Shiqing

Year: 2023

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-125438

Thesis Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy signaling

He, Liumin; Sun, Zhongqing; Li, Jianshuang et al. · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy signaling

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-108787

Thesis Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent

Hou, Xu; Chen, Taylor Hsuan-Yu; Koga, Shunsuke et al. · 2023 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent

Authors: Hou, Xu; Chen, Taylor Hsuan-Yu; Koga, Shunsuke; Bredenberg, Jenny M.; Faroqi, Ayman H.; Delenclos, Marion; Bu, Guojun; Wszolek, Zbigniew K.; Carr, Jonathan A.; Ross, Owen A.; McLean, Pamela J.; Murray, Melissa E.; Dickson, Dennis W.; Fiesel, Fabienne C.; Springer, Wolfdieter

Year: 2023

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130264

Thesis Solving neurodegeneration: common mechanisms and strategies for new treatments

Wareham, Lauren K.; Bu, Guojun; Calkins, David J. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Solving neurodegeneration: common mechanisms and strategies for new treatments

Authors: Wareham, Lauren K.; Bu, Guojun; Calkins, David J.

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130195

Thesis Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Duan, Yangyang; Ye, Tao; Qu, Zhe et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Authors: Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-112438

Thesis Dysregulation of protein trafficking in neurodegeneration

Wang, Xin; Huang, Timothy; Bu, Guojun et al. · 2014 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Dysregulation of protein trafficking in neurodegeneration

Authors: Wang, Xin; Huang, Timothy; Bu, Guojun; Xu, Huaxi

Year: 2014

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130650

Thesis Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms

Li, Jie; Kanekiyo, Takahisa; Shinohara, Mitsuru et al. · 2012 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms

Authors: Li, Jie; Kanekiyo, Takahisa; Shinohara, Mitsuru; Zhang, Yunwu; LaDu, Mary Jo; Xu, Huaxi; Bu, Guojun

Year: 2012

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130984

Thesis Novel neurotrophic treatments in rats and toxin sensitivity of genetically modified mice in the unilateral 6 OHDA model of Parkinson's disease

Piltonen, Marjo · 2012 · University of Helsinki (HELDA) · DOI

Full title: Novel neurotrophic treatments in rats and toxin sensitivity of genetically modified mice in the unilateral 6 OHDA model of Parkinson's disease

Authors: Piltonen, Marjo

Year: 2012

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/37008

Thesis Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

Watzlawik, Jens O.; Hou, Xu; Fricova, Dominika et al. · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

Authors: Watzlawik, Jens O.; Hou, Xu; Fricova, Dominika; Ramnarine, Chloe; Barodia, Sandeep K.; Gendron, Tania F.; Heckman, Michael G.; DeTure, Michael; Siuda, Joanna; Wszolek, Zbigniew K.; Scherzer, Clemens R.; Ross, Owen A.; Bu, Guojun; Dickson, Dennis W.; Goldberg, Matthew S.; Fiesel, Fabienne C.; Springer, Wolfdieter

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130445

Thesis Current Updates on the Role of MicroRNA in the Diagnosis and Treatment of Neurodegenerative Diseases

Saleem, Ammara; Javed, Maira; Akhtar, Muhammad Furqan et al. · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Current Updates on the Role of MicroRNA in the Diagnosis and Treatment of Neurodegenerative Diseases

Authors: Saleem, Ammara; Javed, Maira; Akhtar, Muhammad Furqan; Sharif, Ali; Akhtar, Bushra; Naveed, Muhammad; Saleem, Uzma; Baig, Mirza Muhammad Faran Ashraf; Zubair, Hafiz Muhammad; Emran, Talha Bin; Saleem, Mohammad; Ashraf, Ghulam Md

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-131068

Thesis Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs

Jin, Yunjung; Bu, Guojun; Zhao, Na · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs

Authors: Jin, Yunjung; Bu, Guojun; Zhao, Na

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145427

Thesis Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

Zhang, Xiangnan; Yan, Haijing; Yuan, Yang et al. · 2013 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

Authors: Zhang, Xiangnan; Yan, Haijing; Yuan, Yang; Gao, Jieqiong; Shen, Zhe; Cheng, Yun; Shen, Yao; Wang, Rong-Rong; Wang, Xiaofen; Hu, Wei-Wei; Wang, Guanghui; Chen, Zhong

Year: 2013

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145087

Thesis The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation

Li, Jiahua; Ng, Ka Wai; Sung, Chun Chau et al. · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation

Authors: Li, Jiahua; Ng, Ka Wai; Sung, Chun Chau; Chung, Ka Kin Kenny

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-138296

Thesis The role of polo-like kinases 2 in the proteasomal and lysosomal degradation of alpha-synuclein in neurons

Sung, Chun Chau; Lam, Wai Yun; Chung, Ka Kin Kenny · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The role of polo-like kinases 2 in the proteasomal and lysosomal degradation of alpha-synuclein in neurons

Authors: Sung, Chun Chau; Lam, Wai Yun; Chung, Ka Kin Kenny

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-144852

Thesis Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Aβ42 uptake and lysosomal trafficking

Fuentealba, Rodrigo A.; Liu, Qiang; Zhang, Juan et al. · 2010 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Aβ42 uptake and lysosomal trafficking

Authors: Fuentealba, Rodrigo A.; Liu, Qiang; Zhang, Juan; Kanekiyo, Takahisa; Hu, Xiaoyan; Lee, Jin-Moo; Ladu, Mary Jo; Bu, Guojun

Year: 2010

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-131027

Thesis Microglial Lyzl4 Facilitates β-Amyloid Clearance in Alzheimer's Disease

Pan, Jie; Zhong, Jie; Geng, Ji et al. · 2025 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Microglial Lyzl4 Facilitates β-Amyloid Clearance in Alzheimer's Disease

Authors: Pan, Jie; Zhong, Jie; Geng, Ji; Oberhauser, Jane; Shi, Shihua; Wan, Jun

Year: 2025

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145463

Thesis Autophagy in adult stem cell homeostasis, aging, and disease therapy

Zhao, Ke; Chan, Tsz Ching; Tse, Erin H. Y. et al. · 2025 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Autophagy in adult stem cell homeostasis, aging, and disease therapy

Authors: Zhao, Ke; Chan, Tsz Ching; Tse, Erin H. Y.; Xie, Zhiyao; Cheung, Tom H.; Zeng, Yi Arial

Year: 2025

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-147163

Thesis The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease

Lee, F.K.M.; Wong, A.K.Y.; Lee, Y.W. et al. · 2009 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease

Authors: Lee, F.K.M.; Wong, A.K.Y.; Lee, Y.W.; Wan, Oi Wan; Chan, H.Y.E.; Chung, Kenny K.K.

Year: 2009

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-30862

Thesis Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

Cheung, Zelda H.; Ip, Nancy Yuk-yu · 2011 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

Authors: Cheung, Zelda H.; Ip, Nancy Yuk-yu

Year: 2011

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-39729

Thesis Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

Zhang, Xiangnan; Yuan, Yang; Jiang, Lei et al. · 2014 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

Authors: Zhang, Xiangnan; Yuan, Yang; Jiang, Lei; Zhang, Jingying; Gao, Jieqiong; Shen, Zhe; Zheng, Yanrong; Deng, Tian; Yan, Haijing; Li, Wenlu; Hou, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Zhang, Zhuohua; Chen, Zhong

Year: 2014

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145090

Thesis Luteolin, a common flavone in vegetables, acts as a hormetin processing neurotrophic function: signaling mediated by inducing mitochondrial stress

Gao, Xiong; Xia, Chenxi; Guo, Suisui et al. · 2025 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Luteolin, a common flavone in vegetables, acts as a hormetin processing neurotrophic function: signaling mediated by inducing mitochondrial stress

Authors: Gao, Xiong; Xia, Chenxi; Guo, Suisui; Yuen, Ka Wing Gary; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung

Year: 2025

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-148345

Thesis The emerging role of autophagy in Parkinson's disease

Cheung, Zelda Hiu Yee BICH; Ip, Nancy Yuk-Yu · 2009 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The emerging role of autophagy in Parkinson's disease

Authors: Cheung, Zelda Hiu Yee BICH; Ip, Nancy Yuk-Yu

Year: 2009

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-30195

Thesis Molecular machinery of macroautophagy and its deregulation in diseases

Wong, Alan S.L.; Cheung, Zelda H Y; Ip, Nancy Yuk-yu · 2011 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Molecular machinery of macroautophagy and its deregulation in diseases

Authors: Wong, Alan S.L.; Cheung, Zelda H Y; Ip, Nancy Yuk-yu

Year: 2011

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-44530

Thesis Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

Wong, Alan S.L.; Lee, Rebecca H.K.; Cheung, Anthony Y. et al. · 2011 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

Authors: Wong, Alan S.L.; Lee, Rebecca H.K.; Cheung, Anthony Y.; Yeung, Patrick K.; Chung, Sookja K.; Cheung, Zelda H.; Ip, Nancy Yuk-yu

Year: 2011

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-40044

Thesis The PI3K-Akt-mTOR pathway regulates a oligomer induced neuronal cell cycle events

Bhaskar, Kiran; Miller, Megan; Chludzinski, Alexandra et al. · 2009 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The PI3K-Akt-mTOR pathway regulates a oligomer induced neuronal cell cycle events

Authors: Bhaskar, Kiran; Miller, Megan; Chludzinski, Alexandra; Herrup, Karl; Zagorski, Michael; Lamb, Bruce

Year: 2009

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-53266

Thesis Current conceptual view of Alzheimer's disease

Herrup, Karl · 2012 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Current conceptual view of Alzheimer's disease

Authors: Herrup, Karl

Year: 2012

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-53196

Thesis The Protective Role of microRNA-200c in Alzheimer's Disease Pathologies Is Induced by Beta Amyloid-Triggered Endoplasmic Reticulum Stress

Wu, Qi; Ye, Xiaoyang; Xiong, Yi et al. · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The Protective Role of microRNA-200c in Alzheimer's Disease Pathologies Is Induced by Beta Amyloid-Triggered Endoplasmic Reticulum Stress

Authors: Wu, Qi; Ye, Xiaoyang; Xiong, Yi; Zhu, Haili; Miao, Jianting; Zhang, Wei; Wan, Jun

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-83155

Thesis The Role of Alpha-Synuclein Oligomerization and Aggregation in Cellular and Animal Models of Parkinson's Disease

Wan, Oi Wan; Chung, Kenny K.K. · 2012 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The Role of Alpha-Synuclein Oligomerization and Aggregation in Cellular and Animal Models of Parkinson's Disease

Authors: Wan, Oi Wan; Chung, Kenny K.K.

Year: 2012

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-55098

Thesis MicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies

Ye, Xiaoyang; Luo, Hongxue; Chen, Yan et al. · 2015 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: MicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies

Authors: Ye, Xiaoyang; Luo, Hongxue; Chen, Yan; Wu, Qi; Xiong, Yi; Zhu, Yinyong; Diao, Yarui; Wu, Zhenguo; Miao, Jianting; Wan, Jun

Year: 2015

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-74921

Thesis A Natural Diarylheptanoid Protects Cortical Neurons Against Oxygen-glucose Deprivation-induced Autophagy and Apoptosis

Shi, Qiaoyun; Zhang, Qinghua; Peng, Yinghui et al. · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: A Natural Diarylheptanoid Protects Cortical Neurons Against Oxygen-glucose Deprivation-induced Autophagy and Apoptosis

Authors: Shi, Qiaoyun; Zhang, Qinghua; Peng, Yinghui; Zhang, Xiaoqi; Wang, Ying; Shi, Lei

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-98781

Thesis A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

Song, Juxian; Sun, Yueru; Peluso, Ivana et al. · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

Authors: Song, Juxian; Sun, Yueru; Peluso, Ivana; Zeng, Yu; Yu, Xing; Lu, Jiahong; Xu, Zheng; Wang, Mingzhong; Liu, Liangfeng; Huang, Yingyu; Chen, Leilei; Durairajan, Siva Sundara Kumar; Zhang, Hongjie; Zhou, Bo; Zhang, Hongqi; Lu, Aiping; Ballabio, Andrea; Medina, Diego Luis; Guo, Zhihong; Li, Min

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-80698

Thesis Motor Neuron-specific Disruption of Proteasomes, but not Autophagy, Replicates Amyotrophic Lateral Sclerosis.

Tashiro, Yoshitaka · 2013 · Kyoto University · DOI

Full title: Motor Neuron-specific Disruption of Proteasomes, but not Autophagy, Replicates Amyotrophic Lateral Sclerosis.

Authors: Tashiro, Yoshitaka

Year: 2013

Venue: Kyoto University

DOI: http://hdl.handle.net/2433/174828

Thesis Nanoparticles for drug delivery targeting neurodegeneration in brain and eye

Feng, Teng CBME; Huang, Xiaonan; Ni, Rong et al. · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Nanoparticles for drug delivery targeting neurodegeneration in brain and eye

Authors: Feng, Teng CBME; Huang, Xiaonan; Ni, Rong; Suen, Wai Leung Langston; Chau, Ying

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-96464

Thesis Synaptic Dysfunction in Alzheimer's Disease: Mechanisms and Therapeutic Strategies

Chen, Yu LIFS; Fu, Kit Yu; Ip, Nancy Yuk-yu · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Synaptic Dysfunction in Alzheimer's Disease: Mechanisms and Therapeutic Strategies

Authors: Chen, Yu LIFS; Fu, Kit Yu; Ip, Nancy Yuk-yu

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-96142

Thesis Schisandrin B Ameliorates ICV-Infused Amyloid beta Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-kappa B/MAPK and Up-Regulating HSP/Beclin Expression

Giridharan, Vijayasree V.; Thandavarayan, Rajarajan A.; Arumugam, Somasundaram et al. · 2015 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Schisandrin B Ameliorates ICV-Infused Amyloid beta Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-kappa B/MAPK and Up-Regulating HSP/Beclin Expression

Authors: Giridharan, Vijayasree V.; Thandavarayan, Rajarajan A.; Arumugam, Somasundaram; Mizuno, Makoto; Nawa, Hiroyuki; Suzuki, Kenji; Ko, Robert K.M.; Krishnamurthy, Prasanna; Watanabe, Kenichi; Konishi, Tetsuya

Year: 2015

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-74494

Thesis IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai et al. · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Authors: Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-77061

Thesis Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion

Chen, Weitao; Lu, Na; Ding, Yue et al. · 2016 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion

Authors: Chen, Weitao; Lu, Na; Ding, Yue; Wang, Yuan; Chan, Leung Ting; Wang, Xu; Gao, Xin; Jiang, Songshan; Liu, Kai

Year: 2016

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-84096

Thesis C9orf72 Intermediate Repeats Are Associated With Corticobasal Degeneration, Increased C9orf72 Expression And Disruption Of Autophagy

Cali, Christopher P.; Patino, Maribel; Tai, Yee Kit et al. · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: C9orf72 Intermediate Repeats Are Associated With Corticobasal Degeneration, Increased C9orf72 Expression And Disruption Of Autophagy

Authors: Cali, Christopher P.; Patino, Maribel; Tai, Yee Kit; Ho, Wan Yun; McLean, Catriona A.; Morris, Christopher M.; Seeley, William W.; Miller, Bruce L.; Gaig, Carles; Vonsattel, Jean Paul G.; White III, Charles L.; Roeber, Sigrun; Kretzschmar, Hans; Troncoso, Juan C.; Troakes, Claire; Gearing, Marla; Ghetti, Bernardino; Van Deerlin, Vivianna M.; Lee, Virginia Man Yee C.; Trojanowski, John Q.; Mok, Kin Ying Boniface; Ling, Helen; Dickson, Dennis W.; Schellenberg, Gerard D.; Ling, Shuo-Chien; Lee, Edward B.

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-99368

Thesis Translation potential of current preclinical techniques for gene therapy of neurological diseases in clinic. A critical review.

Žideková, Paulína · 2025 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Translation potential of current preclinical techniques for gene therapy of neurological diseases in clinic. A critical review.

Authors: Žideková, Paulína

Year: 2025

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/181322

Thesis Význam neuroinflamácie v neurodegeneratívnych procesoch CNS

Červenák, Karol · 2022 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Význam neuroinflamácie v neurodegeneratívnych procesoch CNS

Authors: Červenák, Karol

Year: 2022

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/173113

Thesis Monitorování vlivu mutovaného huntingtinu na autofagii v lidských nervových kmenových buňkách

Zezulová, Kristýna · 2023 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Monitorování vlivu mutovaného huntingtinu na autofagii v lidských nervových kmenových buňkách

Authors: Zezulová, Kristýna

Year: 2023

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/181343

Thesis Biomarkery mitofagie v kontinuu Alzheimorovy nemoci

Katonová, Alžbeta · 2023 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Biomarkery mitofagie v kontinuu Alzheimorovy nemoci

Authors: Katonová, Alžbeta

Year: 2023

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/185115

Thesis Development and biological characterization of novel ligands for protein-protein interaction-based effects of prolyl oligopeptidase

Kilpeläinen, Tommi · 2021 · University of Helsinki (HELDA) · DOI

Full title: Development and biological characterization of novel ligands for protein-protein interaction-based effects of prolyl oligopeptidase

Authors: Kilpeläinen, Tommi

Year: 2021

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/329940

Thesis The role of autophagy in neurodegenerative processes

Marková, Veronika · 2019 · Charles University Prague (Univerzita Karlova) · DOI

Full title: The role of autophagy in neurodegenerative processes

Authors: Marková, Veronika

Year: 2019

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/105336

Thesis Modulation of Mitophagy in Huntington Disease

Šonský, Ivan · 2022 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Modulation of Mitophagy in Huntington Disease

Authors: Šonský, Ivan

Year: 2022

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/176488

Thesis Neuroprotective activity of some selected phytochemicals in ischemic stroke

Xu, Hui; 徐慧 · 2021 · University of Hong Kong · DOI

Full title: Neuroprotective activity of some selected phytochemicals in ischemic stroke

Authors: Xu, Hui; 徐慧

Year: 2021

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/302566

Thesis Mechanistic study on the inhibition of the late stage of basal autophagy progression by a natural compound (NAADP) and a synthetic small chemical (vacuolin-1)

Lu, Yingying; 卢盈颖 · 2014 · University of Hong Kong · DOI

Full title: Mechanistic study on the inhibition of the late stage of basal autophagy progression by a natural compound (NAADP) and a synthetic small chemical (vacuolin-1)

Authors: Lu, Yingying; 卢盈颖

Year: 2014

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/207179

Thesis The effect of prolyl oligopeptidase inhibition on protein aggregation and oxidative stress in the models of neurodegenerative diseases

Eteläinen, Tony · 2023 · University of Helsinki (HELDA) · DOI

Full title: The effect of prolyl oligopeptidase inhibition on protein aggregation and oxidative stress in the models of neurodegenerative diseases

Authors: Eteläinen, Tony

Year: 2023

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/356152

Thesis Investigating biological mechanisms for the induction of autophagy in neurons stressed by beta-amyloid peptides

Zhang, Qishan; 张绮珊 · 2013 · University of Hong Kong · DOI

Full title: Investigating biological mechanisms for the induction of autophagy in neurons stressed by beta-amyloid peptides

Authors: Zhang, Qishan; 张绮珊

Year: 2013

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/193067

Thesis Role of Atg16L1 in the transport of autophagic vesicles in primary cultured neurons and novel kinases regulating autophagy in fission yeast

Zhou, Peng; 周鵬 · 2017 · University of Hong Kong · DOI

Full title: Role of Atg16L1 in the transport of autophagic vesicles in primary cultured neurons and novel kinases regulating autophagy in fission yeast

Authors: Zhou, Peng; 周鵬

Year: 2017

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/240168

Thesis Elucidating the differential role of the ubiquitin-proteasome system and autophagy in experimental models of Alzheimer's disease

Cheng, Shuk-yee; 鄭淑儀 · 2019 · University of Hong Kong · DOI

Full title: Elucidating the differential role of the ubiquitin-proteasome system and autophagy in experimental models of Alzheimer's disease

Authors: Cheng, Shuk-yee; 鄭淑儀

Year: 2019

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/270250

Thesis Lysosomal Ca²⁺ disruption induces autophagy impairment in familial Alzheimer's disease

Dong, Rui; 董睿 · 2018 · University of Hong Kong · DOI

Full title: Lysosomal Ca²⁺ disruption induces autophagy impairment in familial Alzheimer's disease

Authors: Dong, Rui; 董睿

Year: 2018

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/263177

Thesis Further investigation on biological mechanisms of endoplasmic reticulum aggregation and autophagy triggered by oligomeric beta-amyloid peptides in neurons

Fan, Chi Pang Frankel; 樊志鵬 · 2022 · University of Hong Kong · DOI

Full title: Further investigation on biological mechanisms of endoplasmic reticulum aggregation and autophagy triggered by oligomeric beta-amyloid peptides in neurons

Authors: Fan, Chi Pang Frankel; 樊志鵬

Year: 2022

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/316192

Thesis Investigating metabolomics and the effects of oxyresveratrol in experimental Parkinson's disease

Shah, Anuri · 2019 · University of Hong Kong · DOI

Full title: Investigating metabolomics and the effects of oxyresveratrol in experimental Parkinson's disease

Authors: Shah, Anuri

Year: 2019

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/279793

Thesis MicroRNA-128 ameliorated cognitive deficits and reduced amyloid-beta deposition by inhibiting APPBP2 and mTOR in a mouse model of Alzheimer's disease

Li, Siwen; 李思雯 · 2022 · University of Hong Kong · DOI

Full title: MicroRNA-128 ameliorated cognitive deficits and reduced amyloid-beta deposition by inhibiting APPBP2 and mTOR in a mouse model of Alzheimer's disease

Authors: Li, Siwen; 李思雯

Year: 2022

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/317192

Thesis Investigation of YS620 in regulating beta-amyloid homeostasis via autophagy in Alzheimer's disease

Liu, Rong; 劉榕 · 2021 · University of Hong Kong · DOI

Full title: Investigation of YS620 in regulating beta-amyloid homeostasis via autophagy in Alzheimer's disease

Authors: Liu, Rong; 劉榕

Year: 2021

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/297538

Thesis Study on the identification of small molecule activators of the autophagic pathway and elucidation of the mechanism of action

Law, Yuen-kwan.; 羅婉君. · 2009 · University of Hong Kong · DOI

Full title: Study on the identification of small molecule activators of the autophagic pathway and elucidation of the mechanism of action

Authors: Law, Yuen-kwan.; 羅婉君.

Year: 2009

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/56513

Thesis An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ

Stalder, Patrick; Serdiuk, Tetiana; Ghosh, Dhiman et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ

Authors: Stalder, Patrick; Serdiuk, Tetiana; Ghosh, Dhiman; Fleischmann, Yanick; Ait‐Bouziad, Nadine; Quast, Jan-Philipp; Malinovska, L.; Ouared, A.; Davranche, Aurélien; Hänseler, Walther; Boudou, Cédric; Tsika, Elpida; Stöhr, Jan; Melki, Ronald; Riek, Roland; de Souza, Nicolas R.; Picotti, Paola

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250163

Thesis Vplyv amyloidu β na funkciu endozómov a lyzozómov

Tmějová, Monika · 2023 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Vplyv amyloidu β na funkciu endozómov a lyzozómov

Authors: Tmějová, Monika

Year: 2023

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/185206

Thesis Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes

Rudinskiy, Mikhail; Morone, Diego; Molinari, Maurizio · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes

Authors: Rudinskiy, Mikhail; Morone, Diego; Molinari, Maurizio

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/245803

Thesis Emerging disease-modifying therapies for Parkinson’s disease Nouvelles stratégies thérapeutiques dans la maladie de Parkinson

Mahul-Mellier, Anne Laure; Hubsch, Cécile; Castro, Mayté et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Emerging disease-modifying therapies for Parkinson’s disease Nouvelles stratégies thérapeutiques dans la maladie de Parkinson

Authors: Mahul-Mellier, Anne Laure; Hubsch, Cécile; Castro, Mayté; D’Esneval, Mathilde; Fleury, Vanessa; Bally, Julien F.

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250040

Thesis Mitophagy in human health, ageing and disease

Picca, Anna; Faitg, Julie; Auwerx, Johan et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mitophagy in human health, ageing and disease

Authors: Picca, Anna; Faitg, Julie; Auwerx, Johan; Ferrucci, Luigi; D'Amico, Davide

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/204328

Thesis Autophagy and LRRK2 in the Aging Brain

Albanese, Federica; Novello, Salvatore; Morari, Michele · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Autophagy and LRRK2 in the Aging Brain

Authors: Albanese, Federica; Novello, Salvatore; Morari, Michele

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/164434

Thesis Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease?

Burtscher, Johannes; Syed, Muhammed Muazzam Kamil; Lashuel, Hilal A. et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease?

Authors: Burtscher, Johannes; Syed, Muhammed Muazzam Kamil; Lashuel, Hilal A.; Millet, Gregoire P.

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/176351

Thesis Viral vectors, animal models and new therapies for Parkinson's disease

Schneider, B; Zufferey, R; Aebischer, P · 2008 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Viral vectors, animal models and new therapies for Parkinson's disease

Authors: Schneider, B; Zufferey, R; Aebischer, P

Year: 2008

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/31565

Thesis Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy

Luan, Peiling; D'Amico, Davide; Andreux, Penelope A. et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy

Authors: Luan, Peiling; D'Amico, Davide; Andreux, Penelope A.; Laurila, Pirkka-Pekka; Wohlwend, Martin; Li, Hao; de Lima, Tanes Imamura; Place, Nicolas; Rinsch, Chris; Zanou, Nadege; Auwerx, Johan

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/177908

Thesis alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease

Lo Bianco, C.; Ridet, J. L.; Schneider, B. L. et al. · 2007 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease

Authors: Lo Bianco, C.; Ridet, J. L.; Schneider, B. L.; Deglon, N.; Aebischer, P.

Year: 2007

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/3745

Thesis Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

Chu, Y; Dodiya, H; Aebischer, P et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

Authors: Chu, Y; Dodiya, H; Aebischer, P; Olanow, CW; Kordower, JH

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/44427

Thesis Post-translational glycosylation diminishes α-synuclein pathology formation

Pratt, Matthew; Lashuel, Hilal · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Post-translational glycosylation diminishes α-synuclein pathology formation

Authors: Pratt, Matthew; Lashuel, Hilal

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/206392

Thesis Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

Higashi, Shinji; Moore, Darren J.; Minegishi, Michiko et al. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

Authors: Higashi, Shinji; Moore, Darren J.; Minegishi, Michiko; Kasanuki, Koji; Fujishiro, Hiroshige; Kabuta, Tomohiro; Togo, Takashi; Katsuse, Omi; Uchikado, Hirotake; Furukawa, Yoshiko; Hino, Hiroaki; Kosaka, Kenji; Sato, Kiyoshi; Arai, Heii; Wada, Keiji; Iseki, Eizo

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/74311

Thesis Genetic Mouse Models of Neurodegenerative Diseases

Trancikova, Alzbeta; Ramonet, David; Moore, Darren J. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Genetic Mouse Models of Neurodegenerative Diseases

Authors: Trancikova, Alzbeta; Ramonet, David; Moore, Darren J.

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/74071

Thesis Viral-based modelling and correction of neurodegenerative diseases by RNA interference

Raoul, C.; Barker, S. D.; Aebischer, P. · 2008 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Viral-based modelling and correction of neurodegenerative diseases by RNA interference

Authors: Raoul, C.; Barker, S. D.; Aebischer, P.

Year: 2008

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/27835

Thesis SIRT1/PGC-1: A neuroprotective axis? [SIRT1/PGC-1: Un axe neuroprotecteur?]

Rasouri, S.; Lagouge, M.; Auwerx, J. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: SIRT1/PGC-1: A neuroprotective axis? [SIRT1/PGC-1: Un axe neuroprotecteur?]

Authors: Rasouri, S.; Lagouge, M.; Auwerx, J.

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/37036

Thesis A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration

Gräff, Johannes; Kahn, Martin; Samiei, Alireza et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration

Authors: Gräff, Johannes; Kahn, Martin; Samiei, Alireza; Gao, Jun; Ota, Kristie T.; Rei, Damien; Tsai, Li-Huei

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/96509

Thesis Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases

Finsterwald, Charles; Magistretti, Pierre J.; Lengacher, Sylvain · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases

Authors: Finsterwald, Charles; Magistretti, Pierre J.; Lengacher, Sylvain

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/119051

Thesis Role of the FoxO3a Transcription Factor in alpha-synuclein Induced Neurodegeneration

Pino, Emilda · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Role of the FoxO3a Transcription Factor in alpha-synuclein Induced Neurodegeneration

Authors: Pino, Emilda

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/71747

Thesis Enhancing mitochondrial proteostasis reduces amyloid-beta proteotoxicity

Sorrentino, Vincenzo; Romani, Mario; Ouchiroud, Laurent M. et al. · 2018 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Enhancing mitochondrial proteostasis reduces amyloid-beta proteotoxicity

Authors: Sorrentino, Vincenzo; Romani, Mario; Ouchiroud, Laurent M.; Beck, John S.; Zhang, Hongbo; D'Amico, Davide; Moullan, Norman; Potenza, Francesca; Schmid, Adrien W.; Rietsch, Solene; Counts, Scott E.; Auwerx, Johan

Year: 2018

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/144033

Thesis Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

Shchors, Ksenya; Massaras, Aristea; Hanahan, Douglas · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

Authors: Shchors, Ksenya; Massaras, Aristea; Hanahan, Douglas

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/121099

Thesis Alpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease

Bobela, Wojciech; Aebischer, Patrick; Schneider, Bernard L · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Alpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease

Authors: Bobela, Wojciech; Aebischer, Patrick; Schneider, Bernard L

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/123940

Thesis Involvement of autophagy in hypoxic-excitotoxic neuronal death

Ginet, Vanessa; Spiehlmann, Amelie; Rummel, Coralie et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Involvement of autophagy in hypoxic-excitotoxic neuronal death

Authors: Ginet, Vanessa; Spiehlmann, Amelie; Rummel, Coralie; Rudinskiy, Nikita; Grishchuk, Yulia; Luthi-Carter, Ruth; Clarke, Peter G. H.; Truttmann, Anita C.; Puyal, Julien

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/104298

Thesis Use of lentiviral vectors for modelling and treating Parkinson's disease

Lo Bianco, Christophe · 2005 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Use of lentiviral vectors for modelling and treating Parkinson's disease

Authors: Lo Bianco, Christophe

Year: 2005

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/212534

Thesis Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration

Tsika, Elpida; Kannan, Meghna; Foo, Caroline Shi-Yan et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration

Authors: Tsika, Elpida; Kannan, Meghna; Foo, Caroline Shi-Yan; Dikeman, Dustin; Glauser, Liliane; Gellhaar, Sandra; Gaiter, Dagmar; Knott, Graham W.; Dawson, Ted M.; Dawson, Valina L.; Moore, Darren J.

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/108648

Thesis Dopamine induces soluble alpha-synuclein oligomers and nigrostriatal degeneration

Mor, Danielle E.; Tsika, Elpida; Mazzulli, Joseph R. et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Dopamine induces soluble alpha-synuclein oligomers and nigrostriatal degeneration

Authors: Mor, Danielle E.; Tsika, Elpida; Mazzulli, Joseph R.; Gould, Neal S.; Kim, Hanna; Daniels, Malcolm J.; Doshi, Shachee; Gupta, Preetika; Grossman, Jennifer L.; Tan, Victor X.; Kalb, Robert G.; Caldwell, Kim A.; Caldwell, Guy A.; Wolfe, John H.; Ischiropoulos, Harry

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/142612

Thesis Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Vicente Miranda, Hugo; Szego, Éva M; Oliveira, Luís M A et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Authors: Vicente Miranda, Hugo; Szego, Éva M; Oliveira, Luís M A; Breda, Carlo; Darendelioglu, Ekrem; de Oliveira, Rita M; Ferreira, Diana G; Gomes, Marcos A; Rott, Ruth; Oliveira, Márcia; Munari, Francesca; Enguita, Francisco J; Simões, Tânia; Rodrigues, Eva F; Heinrich, Michael; Martins, Ivo C; Zamolo, Irina; Riess, Olaf; Cordeiro, Carlos; Ponces-Freire, Ana; Lashuel, Hilal A; Santos, Nuno C; Lopes, Luisa V; Xiang, Wei; Jovin, Thomas M; Penque, Deborah; Engelender, Simone; Zweckstetter, Markus; Klucken, Jochen; Giorgini, Flaviano; Quintas, Alexandre; Outeiro, Tiago F

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/136622

Thesis UNDERSTANDING MOTOR NEURON BIOLOGY TO ADVANCE ALS THERAPEUTICS

Wlaschin, Josette · 2025 · Johns Hopkins University · DOI

Full title: UNDERSTANDING MOTOR NEURON BIOLOGY TO ADVANCE ALS THERAPEUTICS

Authors: Wlaschin, Josette

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70563

Thesis Altering protein folding, intracellular signaling, or the post-transcriptional program as potential therapeutic strategies to counteract Huntington's disease

Perrin, Valérie · 2006 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Altering protein folding, intracellular signaling, or the post-transcriptional program as potential therapeutic strategies to counteract Huntington's disease

Authors: Perrin, Valérie

Year: 2006

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/233907

Thesis PHARMACOLOGICAL PINK1 ACTIVATION MITIGATES PARKINSON’S PATHOLOGY VIA MITOCHONDRIAL BIOGENESIS

Niu, Steve · 2025 · Johns Hopkins University · DOI

Full title: PHARMACOLOGICAL PINK1 ACTIVATION MITIGATES PARKINSON’S PATHOLOGY VIA MITOCHONDRIAL BIOGENESIS

Authors: Niu, Steve

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70903

Thesis Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration

Liddell, JR · 2018 · University of Melbourne · DOI

Full title: Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration

Authors: Liddell, JR

Year: 2018

Venue: University of Melbourne

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000219096600009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c

Thesis DISCOVERING CELL TYPE-SPECIFIC MECHANISMS OF PATHOGENESIS IN CHARCOT-MARIE-TOOTH TYPE 4B3

Sharma, Malika · 2025 · Johns Hopkins University · DOI

Full title: DISCOVERING CELL TYPE-SPECIFIC MECHANISMS OF PATHOGENESIS IN CHARCOT-MARIE-TOOTH TYPE 4B3

Authors: Sharma, Malika

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70941

Thesis Longevity pathways (mTOR, SIRT, Insulin/IGF-1) as key modulatory targets on aging and neurodegeneration

Kawamoto, Elisa Mitiko · 2015 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Longevity pathways (mTOR, SIRT, Insulin/IGF-1) as key modulatory targets on aging and neurodegeneration

Authors: Kawamoto, Elisa Mitiko

Year: 2015

Venue: Universidade de São Paulo – USP Digital Library

DOI: http://www.ingentaconnect.com/content/ben/ctmc/2015/00000015/00000021/art00003?token%3D004f128b877b76504c48666725533a766c7c3f252d7c6a332b25757d5c4f6d4e227aa1af2e9e3b0

Thesis Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

Haque, ME; Akther, M; Jakaria, M et al. · 2020 · University of Melbourne · DOI

Full title: Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

Authors: Haque, ME; Akther, M; Jakaria, M; Kim, IS; Azam, S; Choi, DK

Year: 2020

Venue: University of Melbourne

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493889400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c

Thesis Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer's Disease: Mechanisms, Drug Candidates, and New Opportunities

Fu, Wing-Yu LIFS; Wang, Xiujiao; Ip, Nancy Yuk-yu · 2019 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer's Disease: Mechanisms, Drug Candidates, and New Opportunities

Authors: Fu, Wing-Yu LIFS; Wang, Xiujiao; Ip, Nancy Yuk-yu

Year: 2019

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-96073

Thesis Investigating disease mechanisms and potential drug treatments in a transgenic zebrafish model of Machado-Joseph disease

Watchon, Maxinne · 2019 · University of Sydney · DOI

Full title: Investigating disease mechanisms and potential drug treatments in a transgenic zebrafish model of Machado-Joseph disease

Authors: Watchon, Maxinne

Year: 2019

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/20272

Thesis TLR2 and α-synuclein mediated pathology in human neuronal cell models

Gao, Jianqun · 2019 · University of Sydney · DOI

Full title: TLR2 and α-synuclein mediated pathology in human neuronal cell models

Authors: Gao, Jianqun

Year: 2019

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/20502

Thesis Novel Multi-Functional Therapeutics for the Treatment of Alzheimer’s Disease

Wu, Zhixuan · 2018 · University of Sydney · DOI

Full title: Novel Multi-Functional Therapeutics for the Treatment of Alzheimer’s Disease

Authors: Wu, Zhixuan

Year: 2018

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/20214

Thesis Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration

Quick, Joseph D; Silva, Cristian; Wong, Jia Hui et al. · 2023 · Imperial College London · DOI

Full title: Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration

Authors: Quick, Joseph D; Silva, Cristian; Wong, Jia Hui; Lim, Kah Leong; Reynolds, Richard; Barron, Anna M; Zeng, Jialiu; Lo, Chih Hung

Year: 2023

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/37543564

Thesis Pharmacophore Exploration of Small Molecules Targeting Protein Aggregation for the Treatment of Neurodegenerative Diseases

Callis, Timothy · 2022 · University of Sydney · DOI

Full title: Pharmacophore Exploration of Small Molecules Targeting Protein Aggregation for the Treatment of Neurodegenerative Diseases

Authors: Callis, Timothy

Year: 2022

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/28101

Thesis Novel in situ seeding immunodetection assay uncovers neuronal-driven alpha-synuclein seeding in Parkinson’s disease

Otero Jimenez, Maria; Wojewska, Marcelina; Jogaudaite, Simona et al. · 2025 · Imperial College London · DOI

Full title: Novel in situ seeding immunodetection assay uncovers neuronal-driven alpha-synuclein seeding in Parkinson’s disease

Authors: Otero Jimenez, Maria; Wojewska, Marcelina; Jogaudaite, Simona; Miller, david; Gray-Rodriguez, Sandra; Geoghegan, Grainne; Abelleira-Hervas, Laura; viney, tim; Sarkany, Barbara; Gveric, Djordje; Gentleman, Steve; Alegre Abarrategui, Javier

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/122932

Thesis Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease

Asimakidou, Evridiki; Reynolds, Richard; Barron, Anna M et al. · 2025 · Imperial College London · DOI

Full title: Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease

Authors: Asimakidou, Evridiki; Reynolds, Richard; Barron, Anna M; Lo, Chih Hung

Year: 2025

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/38227498

Thesis Synthetic biology and therapeutic strategies for the degenerating brain: Synthetic biology approaches can transform classical cell and gene therapies, to provide new cures for neurodegenerative diseases.

Agustín-Pavón, C; Isalan, M · 2014 · Imperial College London · DOI

Full title: Synthetic biology and therapeutic strategies for the degenerating brain: Synthetic biology approaches can transform classical cell and gene therapies, to provide new cures for neurodegenerative diseases.

Authors: Agustín-Pavón, C; Isalan, M

Year: 2014

Venue: Imperial College London

DOI: http://www.ncbi.nlm.nih.gov/pubmed/25100403

Thesis Development of an adeno-associated virus-based gene therapy for the treatment of amyotrophic lateral sclerosis: A focus on the gene delivery to the central nervous system

Merjane, Jessica · 2023 · University of Sydney · DOI

Full title: Development of an adeno-associated virus-based gene therapy for the treatment of amyotrophic lateral sclerosis: A focus on the gene delivery to the central nervous system

Authors: Merjane, Jessica

Year: 2023

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/31869

Thesis Nanostars carrying multifunctional neurotrophic dendrimers protect neurons in preclinical in vitro models of neurodegenerative disorders

Morfill, Corinne; Pankratova, Stanislava; Machado, Pedro et al. · 2024 · Imperial College London · DOI

Full title: Nanostars carrying multifunctional neurotrophic dendrimers protect neurons in preclinical in vitro models of neurodegenerative disorders

Authors: Morfill, Corinne; Pankratova, Stanislava; Machado, Pedro; Fernando, Nathalie K; Regoutz, Anna; Talamona, Federica; Pinna, Alessandra; Klosowski, Michal; Wilkinson, Robert J; Fleck, Roland A; Xie, Fang; Porter, Alexandra E; Kiryushko, Darya

Year: 2024

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000869075300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease

Irvine, Elaine; Katsouri, Loukia; Plattner, Florian et al. · 2019 · Imperial College London · DOI

Full title: Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease

Authors: Irvine, Elaine; Katsouri, Loukia; Plattner, Florian; Al-Qassab, Hind; Al-Nackkash, Rand; Bates, Gillian; Withers, Dominic

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/74519

Thesis Focus on the role of D-serine and D-amino acid oxidase in Amyotrophic Lateral Sclerosis/ Motor Neuron Disease (ALS)

de Belleroche, JS; Kondori, Nazanin Rahmani; Paul, Praveen et al. · 2018 · Imperial College London · DOI

Full title: Focus on the role of D-serine and D-amino acid oxidase in Amyotrophic Lateral Sclerosis/ Motor Neuron Disease (ALS)

Authors: de Belleroche, JS; Kondori, Nazanin Rahmani; Paul, Praveen; Robbins, Jacqueline; Liu, Ke; Hildyard, John; Wells, Dominic

Year: 2018

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/56287

Thesis The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death

Kaliszczak, Maciej; Hechanova, Erich; Alsadah, Hibah et al. · 2018 · Imperial College London · DOI

Full title: The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death

Authors: Kaliszczak, Maciej; Hechanova, Erich; Alsadah, Hibah; Li, Millie; Parzych, Katarzyna; Auner, Holger; Aboagye, EO

Year: 2018

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/62884

Thesis Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-beta Precursor Protein (vol 32, pg 4410, 2012)

Parr, C; Carzaniga, R; Gentleman, SM et al. · 2016 · Imperial College London · DOI

Full title: Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-beta Precursor Protein (vol 32, pg 4410, 2012)

Authors: Parr, C; Carzaniga, R; Gentleman, SM; Van Leuven, F; Walter, J; Sastre, M

Year: 2016

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/35990

Thesis Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: phenotype and loss of spinal cord motor neurons

Kondori, NR; Paul, P; Robbins, JP et al. · 2017 · Imperial College London · DOI

Full title: Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: phenotype and loss of spinal cord motor neurons

Authors: Kondori, NR; Paul, P; Robbins, JP; Liu, K; Hildyard, JCW; de Belleroche, JS

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/53968

Thesis Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains

Vaillant-Beuchot, Loan; Mary, Arnaud; Pardossi-Piquard, Raphaëlle et al. · 2020 · Imperial College London · DOI

Full title: Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains

Authors: Vaillant-Beuchot, Loan; Mary, Arnaud; Pardossi-Piquard, Raphaëlle; Bourgeois, Alexandre; Lauritzen, Inger; Eysert, Fanny; Kinoshita, Paula Fernanda; Cazareth, Julie; Badot, Céline; Fragaki, Konstantina; Bussiere, Renaud; Martin, Cécile; Mary, Rosanna; Bauer, Charlotte; Pagnotta, Sophie; Paquis-Flucklinger, Véronique; Buée-Scherrer, Valérie; Buée, Luc; Lacas-Gervais, Sandra; Checler, Frédéric; Chami, Mounia

Year: 2020

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/33079262

Thesis Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction

Jung, Yooju; Lee, Seung-Eun; Kang, Insung et al. · 2022 · Seoul National University · DOI

Full title: Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction

Authors: Jung, Yooju; Lee, Seung-Eun; Kang, Insung; Cho, Sung Min; Kang, Kyung-Sun; Kwon, Ho Jeong

Year: 2022

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/183187

Thesis Graphene Quantum Dots Alleviate Impaired Functions in Niemann-Pick Disease Type C in Vivo

Kang, Insung; Yoo, Je Min; Kim, Donghoon et al. · 2022 · Seoul National University · DOI

Full title: Graphene Quantum Dots Alleviate Impaired Functions in Niemann-Pick Disease Type C in Vivo

Authors: Kang, Insung; Yoo, Je Min; Kim, Donghoon; Kim, Juhee; Cho, Myung Keun; Lee, Seung-Eun; Kim, Dong Jin; Lee, Byung-Chul; Lee, Jin Young; Kim, Jae-Jun; Shin, Nari; Choi, Soon Won; Lee, Young-Ho; Ko, Han Seok; Shin, Seokmin; Hong, Byung Hee; Kang, Kyung-Sun

Year: 2022

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/178080

Thesis Synthesis, in vitro and in vivo evaluation of nanoparticles and metal complexes for the treatment of brain diseases

Chan, Tiffany · 2022 · Imperial College London · DOI

Full title: Synthesis, in vitro and in vivo evaluation of nanoparticles and metal complexes for the treatment of brain diseases

Authors: Chan, Tiffany

Year: 2022

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/95087

Thesis Impairment of macroautophagy in dopamine neurons has opposing effects on Parkinsonian pathology and behavior

Hunn, Benjamin HM; Vingill, Siv; Threlfell, Sarah et al. · 2019 · Imperial College London · DOI

Full title: Impairment of macroautophagy in dopamine neurons has opposing effects on Parkinsonian pathology and behavior

Authors: Hunn, Benjamin HM; Vingill, Siv; Threlfell, Sarah; Alegre-Abarrategui, Javier; Magdelyns, Morgane; Deltheil, Thierry; Bengoa-Vergniory, Nora; Oliver, Peter L; Cioroch, Milena; Doig, Natalie M; Bannerman, David M; Cragg, Stephanie J; Wade-Martins, Richard

Year: 2019

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000491881400011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Preclinical testing of potential therapeutics for Amyotrophic Lateral Sclerosis

Kaneb, Hannah Marlene Jostock · 2012 · Imperial College London · DOI

Full title: Preclinical testing of potential therapeutics for Amyotrophic Lateral Sclerosis

Authors: Kaneb, Hannah Marlene Jostock

Year: 2012

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/9606

Thesis Effets de la régulation de la protéostasie sur la jonction neuromusculaire dans un modèle de sclérose latérale amyotrophique

Fiore, Frédéric · 2021 · Université de Montréal (Papyrus) · DOI

Full title: Effets de la régulation de la protéostasie sur la jonction neuromusculaire dans un modèle de sclérose latérale amyotrophique

Authors: Fiore, Frédéric

Year: 2021

Venue: Université de Montréal (Papyrus)

DOI: http://hdl.handle.net/1866/25680

Thesis FTD and ALS-translating mouse studies into clinical trials

Ittner, LM; https://orcid.org/0000-0001-6738-3825; Halliday, GM et al. · 2015 · UNSW Sydney · DOI

Full title: FTD and ALS-translating mouse studies into clinical trials

Authors: Ittner, LM ; https://orcid.org/0000-0001-6738-3825; Halliday, GM ; https://orcid.org/0000-0003-0422-8398; Kril, JJ; Götz, J; Hodges, JR; Kiernan, MC ; https://orcid.org/0000-0001-9054-026X

Year: 2015

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_36303

Thesis Mechanistic insights of astrocyte-mediated hyperactive autophagy and loss of motor neuron function in SOD1L39R linked amyotrophic lateral sclerosis

Pant, Aditya Bhushan · 2020 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Mechanistic insights of astrocyte-mediated hyperactive autophagy and loss of motor neuron function in SOD1L39R linked amyotrophic lateral sclerosis

Authors: Pant, Aditya Bhushan

Year: 2020

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1007/s12035-020-02006-0

Thesis Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

White, Matthew A.; Lin, Ziqiang; Kim, Eugene et al. · 2020 · University of Cambridge · DOI

Full title: Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

Authors: White, Matthew A.; Lin, Ziqiang; Kim, Eugene; Henstridge, Christopher M.; Pena Altamira, Emiliano; Hunt, Camille K.; Burchill, Ella; Callaghan, Isobel; Loreto, Andrea; Brown-Wright, Heledd; Mead, Richard; Simmons, Camilla; Cash, Diana; Coleman, Michael P.; Sreedharan, Jemeen

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/312059

Thesis Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Angelova, Plamena R.; Choi, Minee L.; Berezhnov, Alexey V. et al. · 2020 · University of Cambridge · DOI

Full title: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Authors: Angelova, Plamena R.; Choi, Minee L.; Berezhnov, Alexey V.; Horrocks, Mathew H.; Hughes, Craig D.; De, Suman; Rodrigues, Margarida; Yapom, Ratsuda; Little, Daniel; Dolt, Karamjit S.; Kunath, Tilo; Devine, Michael J.; Gissen, Paul; Shchepinov, Mikhail S.; Sylantyev, Sergiy; Pavlov, Evgeny V.; Klenerman, David; Abramov, Andrey Y.; Gandhi, Sonia

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/311361

Thesis Developing Therapies for Neurodegenerative Disorders: Insights from Protein Aggregation and Cellular Stress Responses.

Mallucci, Giovanna R; Klenerman, David; Rubinsztein, David C · 2020 · University of Cambridge · DOI

Full title: Developing Therapies for Neurodegenerative Disorders: Insights from Protein Aggregation and Cellular Stress Responses.

Authors: Mallucci, Giovanna R; Klenerman, David; Rubinsztein, David C

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/311394

Thesis Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Angelova, Plamena R.; Choi, Minee L.; Berezhnov, Alexey V. et al. · 2021 · University of Cambridge · DOI

Full title: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/317413

Thesis L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation

Castejón-Vega, Beatriz; Rubio, Alejandro; Pérez-Pulido, Antonio J. et al. · 2021 · University of Cambridge · DOI

Full title: L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation

Authors: Castejón-Vega, Beatriz; Rubio, Alejandro; Pérez-Pulido, Antonio J.; Quiles, José L.; Lane, Jon D.; Fernández-Domínguez, Beatriz; Cachón-González, María Begoña; Martín-Ruiz, Carmen; Sanz, Alberto; Cox, Timothy M.; Alcocer-Gómez, Elísabet; Cordero, Mario D.

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/330783

Thesis Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain

Kuan, Wei‐Li; Alfaidi, Maha; Horne, Catherine B et al. · 2022 · University of Cambridge · DOI

Full title: Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain

Authors: Kuan, Wei‐Li; Alfaidi, Maha; Horne, Catherine B; Vallin, Benjamin; Fox, Sarah; Fazal, Shaline V; Williams‐Gray, Caroline H; Barker, Roger A

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/342795

Thesis A Novel Neurotrophic Drug for Cognitive Enhancement and Alzheimer’s Disease

Chen, Qi; Prior, Marguerite; Dargusch, Richard et al. · 2011 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: A Novel Neurotrophic Drug for Cognitive Enhancement and Alzheimer’s Disease

Authors: Chen, Qi; Prior, Marguerite; Dargusch, Richard; Roberts, Amanda; Riek, Roland; Eichmann, Cédric; Chiruta, Chandramouli; Akaishi, Tatsuhiro; Abe, Kazuho; Maher, Pamela; Schubert, David

Year: 2011

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/43152

Thesis TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

Paolicelli, Rosa C.; Jawaid, Ali; Henstridge, Christopher M. et al. · 2017 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

Authors: Paolicelli, Rosa C.; Jawaid, Ali; Henstridge, Christopher M.; Valeri, Andrea; Merlini, Mario; Robinson, John L.; Lee, Edward B.; Rose, Jamie; Appel, Stanley; Lee, Virginia M.-Y.; Trojanowski, John Q.; Spires-Jones, Tara; Schulz, Paul E.; Rajendran, Lawrence

Year: 2017

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/191644

Thesis Rapamycin Attenuated Zinc-Induced Tau Phosphorylation and Oxidative Stress in Rats: Involvement of Dual mTOR/p70S6K and Nrf2/HO-1 Pathways

Lai, Chencen; Chen, Zhuyi; Ding, Yuanting et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Rapamycin Attenuated Zinc-Induced Tau Phosphorylation and Oxidative Stress in Rats: Involvement of Dual mTOR/p70S6K and Nrf2/HO-1 Pathways

Authors: Lai, Chencen; Chen, Zhuyi; Ding, Yuanting; Chen, Qian; Su, Songbai; Liu, Heng; Ni, Ruiqing; Tang, Zhi

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/534827

Thesis Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes

Rudinskiy, Mikhail; Morone, Diego; Molinari, Maurizio · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes

Authors: Rudinskiy, Mikhail; Morone, Diego; Molinari, Maurizio

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/703209

Thesis An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ

Stalder, Patrick; Serdiuk, Tetiana; Ghosh, Dhiman et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ

Authors: Stalder, Patrick; Serdiuk, Tetiana; Ghosh, Dhiman; Fleischmann, Yanick; Ait-Bouziad, Nadine; Quast, Jan-Philipp; Malinovska, Larisa; Ouared, Allaeddine; Davranche, Aurelien; Hänseler, Walther; id_orcid0000-0003-4868-3704; Boudou, Cedric; Tsika, Elpida; Stöhr, Jan; Melki, Ronald; Riek, Roland; id_orcid0000-0003-4868-3704; de Souza, Natalie; Picotti, Paola

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/736051

Thesis Fragment-based virtual screening identifies a first-in-class preclinical drug candidate for Huntington’s disease

Galyan, Simon Marius; Ewald, Collin; id_orcid0000-0003-1166-4171 et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Fragment-based virtual screening identifies a first-in-class preclinical drug candidate for Huntington’s disease

Authors: Galyan, Simon Marius; Ewald, Collin; id_orcid0000-0003-1166-4171; Jalencas, Xavier; Masrani, Shyam; Meral, Selin; Mestres, Jordi

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/583231

Thesis Imaging alpha-synuclein pathology in Parkinson’s disease

Ni, Ruiqing; id_orcid0000-0002-0793-2113 · 2026 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Imaging alpha-synuclein pathology in Parkinson’s disease

Authors: Ni, Ruiqing; id_orcid0000-0002-0793-2113

Year: 2026

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/782734

Thesis Characterization of lysosomal dysfunction in Parkinson’s disease associated with GBA1 mutations and development of new therapeutic strategies using pharmacological chaperones

Montpeyó Garcia-Moreno, Marta · 2024 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Characterization of lysosomal dysfunction in Parkinson’s disease associated with GBA1 mutations and development of new therapeutic strategies using pharmacological chaperones

Authors: Montpeyó Garcia-Moreno, Marta

Year: 2024

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/693122

Thesis Modeling sporadic Alzheimer's disease using induced pluripotent stem cells

McLaughlin, Heather Ward · 2014 · Harvard University - DASH · DOI

Full title: Modeling sporadic Alzheimer's disease using induced pluripotent stem cells

Authors: McLaughlin, Heather Ward

Year: 2014

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard.inactive:11757

Thesis The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease

Kruyer, Anna · 2015 · Rockefeller University · DOI

Full title: The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease

Authors: Kruyer, Anna

Year: 2015

Venue: Rockefeller University

DOI: https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/281

Thesis Neuroprotective effect of passiflora edulissims against amyloid beta-induced neurotoxicity

Cao, Shuqin · 2021 · Chulalongkorn University · DOI

Full title: Neuroprotective effect of passiflora edulissims against amyloid beta-induced neurotoxicity

Authors: Cao, Shuqin

Year: 2021

Venue: Chulalongkorn University

DOI: https://digital.car.chula.ac.th/chulaetd/12442

Thesis Biochemical and Genetic Studies of Beclin 1 Function in Autophagy

Zhong, Yun · 2009 · Rockefeller University · DOI

Full title: Biochemical and Genetic Studies of Beclin 1 Function in Autophagy

Authors: Zhong, Yun

Year: 2009

Venue: Rockefeller University

DOI: https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/252

Thesis Application of chemical biology for the discovery of inducers of autophagy

Tan, Zher Yin · 2025 · Harvard University - DASH · DOI

Full title: Application of chemical biology for the discovery of inducers of autophagy

Authors: Tan, Zher Yin

Year: 2025

Venue: Harvard University - DASH

DOI: https://dash.harvard.edu/handle/1/42719395

Thesis Investigation of the Endolysosomal Network in a Drosophila Model of Alzheimer’s Disease

Tan, Sher Li · 2023 · University of Adelaide · DOI

Full title: Investigation of the Endolysosomal Network in a Drosophila Model of Alzheimer’s Disease

Authors: Tan, Sher Li

Year: 2023

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/138378

Thesis Analysing the role of autophagy in Alzheimer’s disease pathogenesis using the zebrafish model system

Ganesan, Swamynathan · 2015 · University of Adelaide · DOI

Full title: Analysing the role of autophagy in Alzheimer’s disease pathogenesis using the zebrafish model system

Authors: Ganesan, Swamynathan

Year: 2015

Venue: University of Adelaide

DOI: http://hdl.handle.net/2440/101649

Thesis Regulation of mTOR Signalling and Protein Synthesis via Parkinson's Disease Risk Factors UCHL1 and LRRK2

Dragovelic, Josif Bailey · 2022 · University of Adelaide · DOI

Full title: Regulation of mTOR Signalling and Protein Synthesis via Parkinson's Disease Risk Factors UCHL1 and LRRK2

Authors: Dragovelic, Josif Bailey

Year: 2022

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/136858

Thesis The role of α-synuclein in the pathology of murine mucopolysaccharidosis type IIIA

Soe, Kyaw Kyaw · 2017 · University of Adelaide · DOI

Full title: The role of α-synuclein in the pathology of murine mucopolysaccharidosis type IIIA

Authors: Soe, Kyaw Kyaw

Year: 2017

Venue: University of Adelaide

DOI: http://hdl.handle.net/2440/105248

Thesis Beyond LC3-associated phagocytosis: cross-talk between autophagy and efferocytosis during microglial corpse clearance

Singh, Sanjna · 2023 · University of Adelaide · DOI

Full title: Beyond LC3-associated phagocytosis: cross-talk between autophagy and efferocytosis during microglial corpse clearance

Authors: Singh, Sanjna

Year: 2023

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/140409

Thesis Characterization of novel neuroprotective ligands modulating molecular behavior of alpha synuclein in Parkinson's disease

Toh, Hui Ting · 2014 · Nanyang Technological University (NTU) · DOI

Full title: Characterization of novel neuroprotective ligands modulating molecular behavior of alpha synuclein in Parkinson's disease

Authors: Toh, Hui Ting

Year: 2014

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/61684

Thesis Effects on diet-induced autophagy in metazoa

Fun, Xiu Hui · 2015 · Nanyang Technological University (NTU) · DOI

Full title: Effects on diet-induced autophagy in metazoa

Authors: Fun, Xiu Hui

Year: 2015

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/63807

Thesis Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Shi, Yingxiao; Lin, Shaoyu; Staats, Kim A. et al. · 2018 · Utrecht University · DOI

Full title: Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Authors: Shi, Yingxiao; Lin, Shaoyu; Staats, Kim A.; Li, Yichen; Chang, Wen Hsuan; Hung, Shu Ting; Hendricks, Eric; Linares, Gabriel R.; Wang, Yaoming; Son, Esther Y.; Wen, Xinmei; Kisler, Kassandra; Wilkinson, Brent; Menendez, Louise; Sugawara, Tohru; Woolwine, Phillip; Huang, Mickey; Cowan, Michael J.; Ge, Brandon; Koutsodendris, Nicole; Sandor, Kaitlin P.; Komberg, Jacob; Vangoor, Vamshidhar R.; Senthilkumar, Ketharini; Hennes, Valerie; Seah, Carina; Nelson, Amy R.; Cheng, Tze Yuan; Lee, Shih Jong J.; August, Paul R.; Chen, Jason A.; Wisniewski, Nicholas; Hanson-Smith, Victor; Belgard, T. Grant; Zhang, Alice; Coba, Marcelo; Grunseich, Chris; Ward, Michael E.; Van Den Berg, Leonard H.; Pasterkamp, R. Jeroen; Trotti, Davide; Zlokovic, Berislav V.; Ichida, Justin K.

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/364200

Thesis Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease

Sinnige, Tessa; Yu, Anan; Morimoto, Richard I. · 2020 · Utrecht University · DOI

Full title: Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease

Authors: Sinnige, Tessa; Yu, Anan; Morimoto, Richard I.

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/414654

Thesis Mechanisms of neurodegeneration: Towards a cure for Alzheimer’s disease

Dumbacher, M. · 2018 · Utrecht University · DOI

Full title: Mechanisms of neurodegeneration: Towards a cure for Alzheimer’s disease

Authors: Dumbacher, M.

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/363357

Thesis Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms

van Vliet, Erwin A; Otte, Wim M; Wadman, Wytse J et al. · 2016 · Utrecht University · DOI

Full title: Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms

Authors: van Vliet, Erwin A; Otte, Wim M; Wadman, Wytse J; Aronica, Eleonora; Kooij, Gijs; de Vries, Helga E; Dijkhuizen, Rick M; Gorter, Jan A

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/333062

Thesis Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease

Pasteuning-Vuhman, Svetlana; de Jongh, Rianne; Timmers, Annabel et al. · 2021 · Utrecht University · DOI

Full title: Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease

Authors: Pasteuning-Vuhman, Svetlana; de Jongh, Rianne; Timmers, Annabel; Pasterkamp, R. Jeroen

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440977

Thesis Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo

Spataro, Sofia; Maco, Bohumil; Escrig, Stéphane et al. · 2023 · Utrecht University · DOI

Full title: Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo

Authors: Spataro, Sofia; Maco, Bohumil; Escrig, Stéphane; Jensen, Louise; Polerecky, Lubos; Knott, Graham; Meibom, Anders; Schneider, Bernard l.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/432577

Thesis Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Authors: Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor; Pereira de Almeida, Luís; Cavadas, Cláudia; Guarente, Leonard Pershing

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/107926

Thesis Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

Sarkar, Souvarish; Murphy, Michael A; Dammer, Eric B et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

Authors: Sarkar, Souvarish; Murphy, Michael A; Dammer, Eric B; Olsen, Abby L; Rangaraju, Srikant; Fraenkel, Ernest; Feany, Mel B

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133258.2

Thesis Autophagy promotes cell survival by maintaining NAD levels

Jaenisch, Rudolf · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Autophagy promotes cell survival by maintaining NAD levels

Authors: Jaenisch, Rudolf

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/146848

Thesis Characterizing the Molecular Switch from Proteasomes to Autophagy in Aggresome Processing

Nanduri, Priyaanka · 2015 · Duke University · DOI

Full title: Characterizing the Molecular Switch from Proteasomes to Autophagy in Aggresome Processing

Authors: Nanduri, Priyaanka

Year: 2015

Venue: Duke University

DOI: https://hdl.handle.net/10161/9921

Thesis The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

Brandt, C; Hillmann, P; Noack, A et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

Authors: Brandt, C; Hillmann, P; Noack, A; Römermann, K; Öhler, LA; Rageot, D; Beaufils, F; Melone, A; Sele, AM; Wymann, MP; Fabbro, D; Löscher, W

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/40057

Thesis Toxicant-Induced Mitochondrial Dysfunction and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Gonzalez-Hunt, Claudia Patricia · 2017 · Duke University · DOI

Full title: Toxicant-Induced Mitochondrial Dysfunction and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Authors: Gonzalez-Hunt, Claudia Patricia

Year: 2017

Venue: Duke University

DOI: https://hdl.handle.net/10161/14382

Thesis Transmission and spreading of tauopathy in transgenic mouse brain

Clavaguera, Florence; Bolmont, Tristan; Crowther, R Anthony et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Transmission and spreading of tauopathy in transgenic mouse brain

Authors: Clavaguera, Florence; Bolmont, Tristan; Crowther, R Anthony; Abramowski, Dorothee; Frank, Stephan; Probst, Alphonse; Fraser, Graham; Stalder, Anna K; Beibel, Martin; Staufenbiel, Matthias; Jucker, Mathias; Goedert, Michel; Tolnay, Markus

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/22341

Thesis Dietary mitophagy enhancer: A strategy for healthy brain aging?

Varghese, Nimmy; Werner, Selina; Grimm, Amandine et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Dietary mitophagy enhancer: A strategy for healthy brain aging?

Authors: Varghese, Nimmy; Werner, Selina; Grimm, Amandine; Eckert, Anne

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/46090

Thesis Mechanisms of tau fragmentation, aggregation and degradation in transgenic mouse models

Özcelik, Sefika · 2025 · University of Basel - edoc Repository · DOI

Full title: Mechanisms of tau fragmentation, aggregation and degradation in transgenic mouse models

Authors: Özcelik, Sefika

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/142294

Thesis Molecular Mechanisms of ATG-9 Localization and Function in Neurons

Yang, Sisi · 2022 · Yale University · DOI

Full title: Molecular Mechanisms of ATG-9 Localization and Function in Neurons

Authors: Yang, Sisi

Year: 2022

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/539

Thesis Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Pan, Xuya; He, Xing; Wu, Su et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Authors: Pan, Xuya; He, Xing; Wu, Su; Xiong, Na; Hou, Xinyu; Wang, Heting; Somlo, Diane; Spiess, Martin; Wang, Haiyang; Yang, Jifeng; Li, Chunliang; Li, Shasha; Ma, Wenbin; Chen, Yanming; Cui, Jun; Qi, Ling; Shi, Guojun

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/139881

Thesis Uncovering novel roles for glia in neurodegenerative diseases

Tejwani, Leon Lall · 2021 · Yale University · DOI

Full title: Uncovering novel roles for glia in neurodegenerative diseases

Authors: Tejwani, Leon Lall

Year: 2021

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/178

Thesis Accelerated drug discovery for Amyotrophic Lateral Sclerosis using high-throughput phenotypic drug screening

Cardinali, Alessandra · 2023 · The University of Edinburgh · DOI

Full title: Accelerated drug discovery for Amyotrophic Lateral Sclerosis using high-throughput phenotypic drug screening

Authors: Cardinali, Alessandra

Year: 2023

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/40800

Thesis Bifunctional Molecules that Induce Both Transcytosis and Degradation of Extracellular Proteins

Howell, Rebecca Anne · 2024 · Yale University · DOI

Full title: Bifunctional Molecules that Induce Both Transcytosis and Degradation of Extracellular Proteins

Authors: Howell, Rebecca Anne

Year: 2024

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/1326

Thesis α-Synuclein-dependent Increases in PIP5K1γ Drive Inositol Signaling to Promote Neurotoxicity

Horvath, Jonathan Drummond · 2021 · University of California, Davis · DOI

Full title: α-Synuclein-dependent Increases in PIP5K1γ Drive Inositol Signaling to Promote Neurotoxicity

Authors: Horvath, Jonathan Drummond

Year: 2021

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/54t9p6kx

Thesis The Effective Rescue of Lysosomal Dysfunction in GBA Neural Progenitor Cells with Compound A

Jetha, Simone · 2021 · University of California, San Diego (UCSD) · DOI

Full title: The Effective Rescue of Lysosomal Dysfunction in GBA Neural Progenitor Cells with Compound A

Authors: Jetha, Simone

Year: 2021

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/03c7j448

Thesis Mechanisms of neuronal dysfunction in a genetic model of prion disease

Gruber, Maxwell Albert · 2024 · University of California, San Diego (UCSD) · DOI

Full title: Mechanisms of neuronal dysfunction in a genetic model of prion disease

Authors: Gruber, Maxwell Albert

Year: 2024

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/92j995q5

Thesis Rejuvenation of Nuclear Speckles with Pyrvinium Boosts Proteostasis and Attenuates Tauopathy

Tao, Yuren · 2024 · University of California, San Diego (UCSD) · DOI

Full title: Rejuvenation of Nuclear Speckles with Pyrvinium Boosts Proteostasis and Attenuates Tauopathy

Authors: Tao, Yuren

Year: 2024

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/4t3958vz

Thesis A novel role for SENP3 in iron-chelation induced mitophagy for the treatment of Parkinson’s disease

Waters, Emily · 2020 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: A novel role for SENP3 in iron-chelation induced mitophagy for the treatment of Parkinson’s disease

Authors: Waters, Emily

Year: 2020

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/27262/1/Thesis.docx

Thesis Screening novel bile acid derived compounds for mitochondrial rescue effect in Parkinson's models

Hastings, Chris · 2020 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Screening novel bile acid derived compounds for mitochondrial rescue effect in Parkinson's models

Authors: Hastings, Chris

Year: 2020

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: oai:etheses.whiterose.ac.uk:29209

Thesis Abnormal Lipid Metabolism in Tauopathy Brains: Dysregulation and Intervention

Nie, Yuhang · 2024 · University of California, San Diego (UCSD) · DOI

Full title: Abnormal Lipid Metabolism in Tauopathy Brains: Dysregulation and Intervention

Authors: Nie, Yuhang

Year: 2024

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/94h3452x

Thesis Investigating mitochondrial and glycolytic phenotypes in Drosophila and patient derived models of C9orf72 Amyotrophic Lateral Sclerosis

Lee, James · 2024 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Investigating mitochondrial and glycolytic phenotypes in Drosophila and patient derived models of C9orf72 Amyotrophic Lateral Sclerosis

Authors: Lee, James

Year: 2024

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/35124/1/James%20Lee%20thesis%20corrected%20final.docx

Thesis The Stratification of Sporadic Parkinson’s Disease Patients by Cellular Mechanism.

Burgess, Toby James · 2024 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: The Stratification of Sporadic Parkinson’s Disease Patients by Cellular Mechanism.

Authors: Burgess, Toby James

Year: 2024

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: oai:etheses.whiterose.ac.uk:36807

Thesis Endoplasmic Reticulum Stress, Regulation of Autophagy and Ubiquitin-proteasome System in Cellular Models of Huntington s Disease

Hyrskyluoto, Alise · 2014 · University of Helsinki (HELDA) · DOI

Full title: Endoplasmic Reticulum Stress, Regulation of Autophagy and Ubiquitin-proteasome System in Cellular Models of Huntington s Disease

Authors: Hyrskyluoto, Alise

Year: 2014

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/135762

Thesis Putative neuroprotective compounds in in vitro models of dopaminergic neurodegeneration

Ossola, Bernardino · 2011 · University of Helsinki (HELDA) · DOI

Full title: Putative neuroprotective compounds in in vitro models of dopaminergic neurodegeneration

Authors: Ossola, Bernardino

Year: 2011

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/27794

Thesis Development and optimisation of tools for preclinical studies on Parkinson's disease

Parkkinen, Ilmari · 2022 · University of Helsinki (HELDA) · DOI

Full title: Development and optimisation of tools for preclinical studies on Parkinson's disease

Authors: Parkkinen, Ilmari

Year: 2022

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/341748

Thesis New insight into mechanisms of transcellular propagation of tau and α-synuclein in neurodegenerative diseases

Yan, Xu · 2017 · University of Helsinki (HELDA) · DOI

Full title: New insight into mechanisms of transcellular propagation of tau and α-synuclein in neurodegenerative diseases

Authors: Yan, Xu

Year: 2017

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/173460

Thesis Vacuolar Storage Disease in Lagotto Romagnolo Dogs : Pathology, autophagy and extracellular vesicles

Syrjä, Pernilla · 2020 · University of Helsinki (HELDA) · DOI

Full title: Vacuolar Storage Disease in Lagotto Romagnolo Dogs : Pathology, autophagy and extracellular vesicles

Authors: Syrjä, Pernilla

Year: 2020

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/320217

Thesis The Effects of Prolyl Oligopeptidase Inhibition in α-Synuclein Based Mouse Models of Parkinson's Disease

Savolainen, Mari · 2015 · University of Helsinki (HELDA) · DOI

Full title: The Effects of Prolyl Oligopeptidase Inhibition in α-Synuclein Based Mouse Models of Parkinson's Disease

Authors: Savolainen, Mari

Year: 2015

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/157017

Thesis Underlying Mechanisms of Prolyl Oligopeptidase Inhibition, Deletion, and Restoration on the α-Synuclein Aggregation Process

Svarcbahs, Reinis · 2019 · University of Helsinki (HELDA) · DOI

Full title: Underlying Mechanisms of Prolyl Oligopeptidase Inhibition, Deletion, and Restoration on the α-Synuclein Aggregation Process

Authors: Svarcbahs, Reinis

Year: 2019

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/287678

Thesis Opening avenues for treatment of neurodegenerative disease using post-biotics: breakthroughs and bottlenecks in clinical translation

Singh, Sachin Kumar · 2024 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Opening avenues for treatment of neurodegenerative disease using post-biotics: breakthroughs and bottlenecks in clinical translation

Authors: Singh, Sachin Kumar

Year: 2024

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://dx.doi.org/10.1016/j.arr.2024.102236

Thesis Effects of treadmill running upon autophagy in the central nervous system of aged rats during prtotein aggregation

Ferrari, Merari de Fátima Ramires · 2014 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Effects of treadmill running upon autophagy in the central nervous system of aged rats during prtotein aggregation

Authors: Ferrari, Merari de Fátima Ramires

Year: 2014

Venue: Universidade de São Paulo – USP Digital Library

DOI: 002682084

Thesis BAG2 prevents Tau hyperphosphorylation and increases p62/SQSTM1 in cell models of neurodegeneration

Ferrari, Merari de Fátima Ramires · 2022 · Universidade de São Paulo – USP Digital Library · DOI

Full title: BAG2 prevents Tau hyperphosphorylation and increases p62/SQSTM1 in cell models of neurodegeneration

Authors: Ferrari, Merari de Fátima Ramires

Year: 2022

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1007/s11033-022-07577-w

Thesis Recent updates in the alzheimer’s disease etiopathology and possible treatment approaches: a narrative review of current clinical trials

Parivar, Kazem · 2020 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Recent updates in the alzheimer’s disease etiopathology and possible treatment approaches: a narrative review of current clinical trials

Authors: Parivar, Kazem

Year: 2020

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.2174/1874467213666200422090135

Thesis Macroautophagy Modulates Synaptic Function in the Striatum

Torres, Ciara · 2014 · Columbia University · DOI

Full title: Macroautophagy Modulates Synaptic Function in the Striatum

Authors: Torres, Ciara

Year: 2014

Venue: Columbia University

DOI: https://doi.org/10.7916/D85T3HJC

Thesis Parkin is downregulated among autophagy-related proteins prior to hyperphosphorylation of Tau in TS65DN mice

Ferrari, Merari de Fátima Ramires · 2021 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Parkin is downregulated among autophagy-related proteins prior to hyperphosphorylation of Tau in TS65DN mice

Authors: Ferrari, Merari de Fátima Ramires

Year: 2021

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1016/j.bbrc.2021.05.016

Thesis Investigating neurodegenerative diseases with small molecule modulators

Letso, Reka Rebecca · 2011 · Columbia University · DOI

Full title: Investigating neurodegenerative diseases with small molecule modulators

Authors: Letso, Reka Rebecca

Year: 2011

Venue: Columbia University

DOI: https://doi.org/10.7916/D8N01DH0

Thesis The autophagosomal perspective: Tissue-specificity and cell-specificity of the autophagic response to starvation in vivo

Yang, Young Joo · 2020 · Columbia University · DOI

Full title: The autophagosomal perspective: Tissue-specificity and cell-specificity of the autophagic response to starvation in vivo

Authors: Yang, Young Joo

Year: 2020

Venue: Columbia University

DOI: https://doi.org/10.7916/d8-9a2y-w195

Thesis Be Eaten to Stay Healthy: Elucidating the Mechanisms of Mitochondrial Quality Control by Mitophagy

de Vries, Rosa Leonora Andrea · 2013 · Columbia University · DOI

Full title: Be Eaten to Stay Healthy: Elucidating the Mechanisms of Mitochondrial Quality Control by Mitophagy

Authors: de Vries, Rosa Leonora Andrea

Year: 2013

Venue: Columbia University

DOI: https://doi.org/10.7916/D81R6QJ2

Thesis Therapeutic strategies targeting FUS toxicity in amyotrophic lateral sclerosis: from a novel mouse model of disease to a first-in-human study

Korobeynikov, Vlad · 2021 · Columbia University · DOI

Full title: Therapeutic strategies targeting FUS toxicity in amyotrophic lateral sclerosis: from a novel mouse model of disease to a first-in-human study

Authors: Korobeynikov, Vlad

Year: 2021

Venue: Columbia University

DOI: https://doi.org/10.7916/d8-ne6n-f498

Thesis Role of motor neuron autophagy in a mouse model of Amyotrophic Lateral Sclerosis

Rudnick, Noam Daniel · 2016 · Columbia University · DOI

Full title: Role of motor neuron autophagy in a mouse model of Amyotrophic Lateral Sclerosis

Authors: Rudnick, Noam Daniel

Year: 2016

Venue: Columbia University

DOI: https://doi.org/10.7916/D8RN380V

Thesis INVESTIGATING THE ROLE OF THE E3 UBIQUITIN LIGASE HECW IN AUTOPHAGY AND STRESS RESPONSE

CESARE, GIULIANA · 2025 · Università degli Studi di Milano (AIR) · DOI

Full title: INVESTIGATING THE ROLE OF THE E3 UBIQUITIN LIGASE HECW IN AUTOPHAGY AND STRESS RESPONSE

Authors: CESARE, GIULIANA

Year: 2025

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1132376

Thesis Quantitative analysis of the focused ultrasound-induced blood-brain barrier opening with applications in neurodegenerative disorders

Karakatsani, Maria Eleni · 2020 · Columbia University · DOI

Full title: Quantitative analysis of the focused ultrasound-induced blood-brain barrier opening with applications in neurodegenerative disorders

Authors: Karakatsani, Maria Eleni

Year: 2020

Venue: Columbia University

DOI: https://doi.org/10.7916/d8-gvqg-2009

Thesis ROLE OF THE PROTEIN QUALITY CONTOL SYSTEM IN MOTOR NEURON DISEASES: THE CASE OF MUSCLE CELLS

CICARDI, MARIA ELENA · 2018 · Università degli Studi di Milano (AIR) · DOI

Full title: ROLE OF THE PROTEIN QUALITY CONTOL SYSTEM IN MOTOR NEURON DISEASES: THE CASE OF MUSCLE CELLS

Authors: CICARDI, MARIA ELENA

Year: 2018

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/585905

Thesis Autophagy-linked FYVE protein mediates the turnover of mutant huntingtin and modifies pathogenesis in mouse models of Huntington’s disease

Fox, Leora Mestel · 2016 · Columbia University · DOI

Full title: Autophagy-linked FYVE protein mediates the turnover of mutant huntingtin and modifies pathogenesis in mouse models of Huntington’s disease

Authors: Fox, Leora Mestel

Year: 2016

Venue: Columbia University

DOI: https://doi.org/10.7916/D83B60CM

Thesis Using selective autophagy to determine protein aggregation's pathogenic contribution to neurodegenerative disease

Croce, Katherine Rose · 2022 · Columbia University · DOI

Full title: Using selective autophagy to determine protein aggregation's pathogenic contribution to neurodegenerative disease

Authors: Croce, Katherine Rose

Year: 2022

Venue: Columbia University

DOI: https://doi.org/10.7916/fp94-wh92

Thesis PERIPHERAL BIOMARKERS AND THERAPEUTIC MODULATION OF PROTEOSTASIS PATHWAYS IN AMYOTROPHIC LATERAL SCLEROSIS

VIZZIELLO, MARIA · 2025 · Università degli Studi di Milano (AIR) · DOI

Full title: PERIPHERAL BIOMARKERS AND THERAPEUTIC MODULATION OF PROTEOSTASIS PATHWAYS IN AMYOTROPHIC LATERAL SCLEROSIS

Authors: VIZZIELLO, MARIA

Year: 2025

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1203055

Thesis The Development of an Inducible Akt as a Potential Gene Therapy for Parkinson’s Disease

Park, Soyeon · 2017 · Columbia University · DOI

Full title: The Development of an Inducible Akt as a Potential Gene Therapy for Parkinson’s Disease

Authors: Park, Soyeon

Year: 2017

Venue: Columbia University

DOI: https://doi.org/10.7916/D8SB4J50

Thesis INHIBITING THE NUCLEAR RECEPTOR ESRRA RESCUES CORE PATHOLOGIES IN CELLULAR AND ANIMAL MODELS OF BATTEN DISEASE

AURILIA, MIRIAM · 2025 · Università degli Studi di Milano (AIR) · DOI

Full title: INHIBITING THE NUCLEAR RECEPTOR ESRRA RESCUES CORE PATHOLOGIES IN CELLULAR AND ANIMAL MODELS OF BATTEN DISEASE

Authors: AURILIA, MIRIAM

Year: 2025

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1202135

Thesis INVESTIGATING THE ROLE OF SNAP29 AND THE AUTOPHAGY PATHWAY IN DROSOPHILA MELANOGASTER MODELS OF C9ORF72 - LINKED ALS/FTD.

SMEELE, PAULIEN HERMINE · 2024 · Università degli Studi di Milano (AIR) · DOI

Full title: INVESTIGATING THE ROLE OF SNAP29 AND THE AUTOPHAGY PATHWAY IN DROSOPHILA MELANOGASTER MODELS OF C9ORF72 - LINKED ALS/FTD.

Authors: SMEELE, PAULIEN HERMINE

Year: 2024

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1115870

Thesis Modulating Proteostatic Stress in Human Motor Neurons to Identify Neuroprotective Targets

Watts, Michelle Elizabeth · 2021 · Harvard University - DASH · DOI

Full title: Modulating Proteostatic Stress in Human Motor Neurons to Identify Neuroprotective Targets

Authors: Watts, Michelle Elizabeth

Year: 2021

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37369444

Thesis Stimulation of mTOR-independent autophagy and mitophagy by rilmenidine exacerbates the phenotype of transgenic TDP-43 mice

Perera, ND; Tomas, D; Wanniarachchillage, N et al. · 2021 · University of Melbourne · DOI

Full title: Stimulation of mTOR-independent autophagy and mitophagy by rilmenidine exacerbates the phenotype of transgenic TDP-43 mice

Authors: Perera, ND; Tomas, D; Wanniarachchillage, N; Cuic, B; Luikinga, SJ; Rytova, V; Turner, BJ

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/281666

Thesis Failure of autophagy–lysosomal pathways in rod photoreceptors causes the early retinal degeneration phenotype observed in Cln6 nclf mice

von Eisenhart-Rothe, P; Grubman, A; Greferath, U et al. · 2021 · University of Melbourne · DOI

Full title: Failure of autophagy–lysosomal pathways in rod photoreceptors causes the early retinal degeneration phenotype observed in Cln6 nclf mice

Authors: von Eisenhart-Rothe, P; Grubman, A; Greferath, U; Fothergill, LJ; Jobling, AI; Phipps, JA; White, AR; Fletcher, EL; Vessey, KA

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/290427

Thesis Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review

Kioussis, B; Tuttle, CSL; Heard, DS et al. · 2022 · University of Melbourne · DOI

Full title: Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review

Authors: Kioussis, B; Tuttle, CSL; Heard, DS; Kennedy, BK; Lautenschlager, NT; Maier, AB

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/309462

Thesis Hyperspectral retinal imaging in mouse models of proteinopathies identifies disease‐specific signatures

De Groef, L; Veys, L; Hadoux, X et al. · 2022 · University of Melbourne · DOI

Full title: Hyperspectral retinal imaging in mouse models of proteinopathies identifies disease‐specific signatures

Authors: De Groef, L; Veys, L; Hadoux, X; Vandenabeele, M; Lemmens, S; Serneels, L; Theunis, J; De Strooper, B; Stalmans, I; van Wijngaarden, P; Moons, L

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/310223

Thesis Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration

Vessey, KA; Jobling, AI; Greferath, U et al. · 2024 · University of Melbourne · DOI

Full title: Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration

Authors: Vessey, KA; Jobling, AI; Greferath, U; Fletcher, EL

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349081

Thesis Walking the tightrope: Proteostasis and neurodegenerative disease

Yerbury, JJ; Ooi, L; Dillin, A et al. · 2016 · University of Melbourne · DOI

Full title: Walking the tightrope: Proteostasis and neurodegenerative disease

Authors: Yerbury, JJ; Ooi, L; Dillin, A; Saunders, DN; Hatters, DM; Beart, PM; Cashman, NR; Wilson, MR; Ecroyd, H

Year: 2016

Venue: University of Melbourne

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000376000500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c

Thesis Biometals and Their Therapeutic Implications in Alzheimer’s Disease

Ayton, S; Lei, P; Bush, AI · 2016 · University of Melbourne · DOI

Full title: Biometals and Their Therapeutic Implications in Alzheimer’s Disease

Authors: Ayton, S; Lei, P; Bush, AI

Year: 2016

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/58959

Thesis Biological metals and metal-targeting compounds in major neurodegenerative diseases

Barnham, KJ; Bush, AI · 2016 · University of Melbourne · DOI

Full title: Biological metals and metal-targeting compounds in major neurodegenerative diseases

Authors: Barnham, KJ; Bush, AI

Year: 2016

Venue: University of Melbourne

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341974600007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c

Thesis A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Cassidy, Liam D; Young, Andrew RJ; Perez-Mancera, Pedro A et al. · 2018 · University of Liverpool · DOI

Full title: A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Authors: Cassidy, Liam D; Young, Andrew RJ; Perez-Mancera, Pedro A; Nimmervoll, Birgit; Jaulim, Adil; Chen, Hung-Chang; McIntyre, Dominick JO; Brais, Rebecca; Ricketts, Thomas; Pacey, Simon; De La Roche, Maike; Gilbertson, Richard J; Rubinsztein, David C; Narita, Masashi

Year: 2018

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3031034

Thesis α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

Wong, Shi Quan; Pontifex, Matthew G; Phelan, Marie M et al. · 2018 · University of Liverpool · DOI

Full title: α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

Authors: Wong, Shi Quan; Pontifex, Matthew G; Phelan, Marie M; Pidathala, Chandra; Kraemer, Brian C; Barclay, Jeff W; Berry, Neil G; O'Neill, Paul M; Burgoyne, Robert D; Morgan, Alan

Year: 2018

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3023681

Thesis [New therapeutic approaches].

Kurz, Alexander; Grimmer, Timo · 2015 · Technical University of Munich (TUM) · DOI

Full title: [New therapeutic approaches].

Authors: Kurz, Alexander;Grimmer, Timo

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1322997

Thesis Autophagy promotes cell survival by maintaining NAD levels

Kataura, Tetsushi; Sedlackova, Lucia; Otten, Elsje G et al. · 2022 · University of Liverpool · DOI

Full title: Autophagy promotes cell survival by maintaining NAD levels

Authors: Kataura, Tetsushi; Sedlackova, Lucia; Otten, Elsje G; Kumari, Ruchika; Shapira, David; Scialo, Filippo; Stefanatos, Rhoda; Ishikawa, Kei-ichi; Kelly, George; Seranova, Elena; Sun, Congxin; Maetzel, Dorothea; Kenneth, Niall; Trushin, Sergey; Zhang, Tong; Trushina, Eugenia; Bascom, Charles C; Tasseff, Ryan; Isfort, Robert J; Oblong, John E; Miwa, Satomi; Lazarou, Michael; Jaenisch, Rudolf; Imoto, Masaya; Saiki, Shinji; Papamichos-Chronakis, Manolis; Manjithaya, Ravi; Maddocks, Oliver DK; Sanz, Alberto; Sarkar, Sovan; Korolchuk, Viktor I

Year: 2022

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3166360

Thesis Gaps Between Aims and Achievements in Therapeutic Modification of Neuronal Damage ("Neuroprotection").

Wiendl, Heinz; Elger, Christian; Förstl, Hans et al. · 2015 · Technical University of Munich (TUM) · DOI

Full title: Gaps Between Aims and Achievements in Therapeutic Modification of Neuronal Damage ("Neuroprotection").

Authors: Wiendl, Heinz;Elger, Christian;Förstl, Hans;Hartung, Hans-Peter;Oertel, Wolfgang;Reichmann, Heinz;Schwab, Stefan

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1323042

Thesis Amyloid clearance as a treatment target against Alzheimer's disease.

Kurz, A; Perneczky, R · 2011 · Technical University of Munich (TUM) · DOI

Full title: Amyloid clearance as a treatment target against Alzheimer's disease.

Authors: Kurz, A;Perneczky, R

Year: 2011

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1100020

Thesis Trifluoperazine rescues human dopaminergic cells from wild-type ?-synuclein-induced toxicity.

Höllerhage, Matthias; Goebel, Joachim N; de Andrade, Anderson et al. · 2014 · Technical University of Munich (TUM) · DOI

Full title: Trifluoperazine rescues human dopaminergic cells from wild-type ?-synuclein-induced toxicity.

Authors: Höllerhage, Matthias;Goebel, Joachim N;de Andrade, Anderson;Hildebrandt, Tobias;Dolga, Amalia;Culmsee, Carsten;Oertel, Wolfgang H;Hengerer, Bastian;Höglinger, Günter U

Year: 2014

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1232704

Thesis Novel insights for the treatment of Alzheimer's disease.

Kurz, A; Perneczky, R · 2011 · Technical University of Munich (TUM) · DOI

Full title: Novel insights for the treatment of Alzheimer's disease.

Authors: Kurz, A;Perneczky, R

Year: 2011

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1074009

Thesis PERK activation mitigates tau pathology in vitro and in vivo.

Bruch, Julius; Xu, Hong; Rösler, Thomas W et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: PERK activation mitigates tau pathology in vitro and in vivo.

Authors: Bruch, Julius;Xu, Hong;Rösler, Thomas W;de Andrade, Anderson;Kuhn, Peer-Hendrik;Lichtenthaler, Stefan F;Arzberger, Thomas;Winklhofer, Konstanze F;Müller, Ulrich;Höglinger, Günter U

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1353464

Thesis Autophagy, prion infection and their mutual interactions.

Heiseke, A; Aguib, Y; Schätzl, HM · 2010 · Technical University of Munich (TUM) · DOI

Full title: Autophagy, prion infection and their mutual interactions.

Authors: Heiseke, A;Aguib, Y;Schätzl, HM

Year: 2010

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1074225

Thesis Preclinical to phase II amyloid beta (A) peptide modulators under investigation for Alzheimer's disease.

Parsons, Chris G; Rammes, Gerhard · 2017 · Technical University of Munich (TUM) · DOI

Full title: Preclinical to phase II amyloid beta (A) peptide modulators under investigation for Alzheimer's disease.

Authors: Parsons, Chris G;Rammes, Gerhard

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1451635

Thesis [Current therapy studies in atypical Parkinson syndromes].

Schweyer, Kerstin; Levin, Johannes; Höglinger, Günter U · 2018 · Technical University of Munich (TUM) · DOI

Full title: [Current therapy studies in atypical Parkinson syndromes].

Authors: Schweyer, Kerstin;Levin, Johannes;Höglinger, Günter U

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587578

Thesis Prion diseases: from molecular biology to intervention strategies.

Nunziante, M; Gilch, S; Schätzl, HM · 2003 · Technical University of Munich (TUM) · DOI

Full title: Prion diseases: from molecular biology to intervention strategies.

Authors: Nunziante, M;Gilch, S;Schätzl, HM

Year: 2003

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1334905

Thesis ROCK inhibition in models of neurodegeneration and its potential for clinical translation

Koch, Jan Christoph; Tatenhorst, Lars; Roser, Anna-Elisa et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: ROCK inhibition in models of neurodegeneration and its potential for clinical translation

Authors: Koch, Jan Christoph;Tatenhorst, Lars;Roser, Anna-Elisa;Saal, Kim-Ann;Toenges, Lars;Lingor, Paul

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587697

Thesis Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing.

Vahsen, Björn Friedhelm; Ribas, Vinicius Toledo; Sundermeyer, Jonas et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing.

Authors: Vahsen, Björn Friedhelm;Ribas, Vinicius Toledo;Sundermeyer, Jonas;Boecker, Alexander;Dambeck, Vivian;Lenz, Christof;Shomroni, Orr;Caldi Gomes, Lucas;Tatenhorst, Lars;Barski, Elisabeth;Roser, Anna-Elisa;Michel, Uwe;Urlaub, Henning;Salinas, Gabriela;Bähr, Mathias;Koch, Jan Christoph;Lingor, Paul

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587876

Thesis Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons.

Hoellerhage, Matthias; Fussi, Natascha; Roesler, Thomas W. et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons.

Authors: Hoellerhage, Matthias;Fussi, Natascha;Roesler, Thomas W.;Wurst, Wolfgang;Behrends, Christian;Hoeglinger, Guenter U.

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1586899

Thesis Therapy in prion diseases: from molecular and cellular biology to therapeutic targets.

Krammer, C; Vorberg, I; Schätzl, HM et al. · 2009 · Technical University of Munich (TUM) · DOI

Full title: Therapy in prion diseases: from molecular and cellular biology to therapeutic targets.

Authors: Krammer, C;Vorberg, I;Schätzl, HM;Gilch, S

Year: 2009

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/824658

Thesis Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation.

Gilch, S; Nunziante, M; Ertmer, A et al. · 2007 · Technical University of Munich (TUM) · DOI

Full title: Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation.

Authors: Gilch, S;Nunziante, M;Ertmer, A;Schätzl, HM

Year: 2007

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/676309

Thesis AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson's Disease.

Balke, Dirk; Tatenhorst, Lars; Dambeck, Vivian et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson's Disease.

Authors: Balke, Dirk;Tatenhorst, Lars;Dambeck, Vivian;Ribas, Vinicius Toledo;Vahsen, Björn F;Michel, Uwe;Bähr, Mathias;Lingor, Paul

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590924

Thesis Autophagy induction by trehalose counteracts cellular prion infection.

Aguib, Y; Heiseke, A; Gilch, S et al. · 2009 · Technical University of Munich (TUM) · DOI

Full title: Autophagy induction by trehalose counteracts cellular prion infection.

Authors: Aguib, Y;Heiseke, A;Gilch, S;Riemer, C;Baier, M;Schätzl, HM;Ertmer, A

Year: 2009

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/824655

Thesis Autophagy, Prion Infection and their Mutual Interactions.

Heiseke, A; Aguib, Y; Schatzl, HM · 2009 · Technical University of Munich (TUM) · DOI

Full title: Autophagy, Prion Infection and their Mutual Interactions.

Authors: Heiseke, A;Aguib, Y;Schatzl, HM

Year: 2009

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/958235

Thesis Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy.

Heiseke, A; Aguib, Y; Riemer, C et al. · 2009 · Technical University of Munich (TUM) · DOI

Full title: Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy.

Authors: Heiseke, A;Aguib, Y;Riemer, C;Baier, M;Schätzl, HM

Year: 2009

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/824657

Thesis Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing

Vahsen, Björn Friedhelm; Ribas, Vinicius Toledo; Sundermeyer, Jonas et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1547017

Thesis Targeting proteostatic maintenance and mitochondrial function with phytochemical compounds in models of brain and skeletal muscle aging

Walsh, Maureen Ann, author; Hamilton, Karyn L., advisor; Fling, Brett W., committee member et al. · 2024 · Colorado State University · DOI

Full title: Targeting proteostatic maintenance and mitochondrial function with phytochemical compounds in models of brain and skeletal muscle aging

Authors: Walsh, Maureen Ann, author; Hamilton, Karyn L., advisor; Fling, Brett W., committee member; Moreno, Julie A., committee member; LaRocca, Thomas J., committee member; Santangelo, Kelly S., committee member

Year: 2024

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/238466

Thesis THERAPEUTIC TARGETING OF VALOSIN-CONTAINING PROTEIN AND STRUCTURAL CHARACTERIZATION OF NEURODEGENERATIVE DISEASE IN SITU

Creekmore, Benjamin, Clyde · 2024 · University of Pennsylvania · DOI

Full title: THERAPEUTIC TARGETING OF VALOSIN-CONTAINING PROTEIN AND STRUCTURAL CHARACTERIZATION OF NEURODEGENERATIVE DISEASE IN SITU

Authors: Creekmore, Benjamin, Clyde

Year: 2024

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/60124

Thesis PATHOPHYSIOLOGY OF VALOSIN-CONTAINING PROTEIN VARIANTS IN FRONTOTEMPORAL DEMENTIA

Phan, Jessica · 2023 · University of Pennsylvania · DOI

Full title: PATHOPHYSIOLOGY OF VALOSIN-CONTAINING PROTEIN VARIANTS IN FRONTOTEMPORAL DEMENTIA

Authors: Phan, Jessica

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/59062

Thesis EXPLORING THE CELL BIOLOGY OF NEURODEGENERATIVE DISEASES AT SCALE

Santhosh Kumar, Saranya · 2024 · University of Pennsylvania · DOI

Full title: EXPLORING THE CELL BIOLOGY OF NEURODEGENERATIVE DISEASES AT SCALE

Authors: Santhosh Kumar, Saranya

Year: 2024

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/60115

Thesis Development of pooled perturbation approaches for neurodegenerative phenotypes and therapeutic strategies

O'Driscoll, Emily, Elizabeth · 2025 · University of Pennsylvania · DOI

Full title: Development of pooled perturbation approaches for neurodegenerative phenotypes and therapeutic strategies

Authors: O'Driscoll, Emily, Elizabeth

Year: 2025

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/61270

Thesis Cargo and Carrier Effects of Rapamycin-Loaded Perfluorocarbon Nanoparticles

Bibee, Kristin Page · 2013 · Washington University in St. Louis · DOI

Full title: Cargo and Carrier Effects of Rapamycin-Loaded Perfluorocarbon Nanoparticles

Authors: Bibee, Kristin Page

Year: 2013

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/80

Thesis Regulation and Function of TREM2-dependent Pathways in Neurodegeneration

Song, Wilbur Madison · 2020 · Washington University in St. Louis · DOI

Full title: Regulation and Function of TREM2-dependent Pathways in Neurodegeneration

Authors: Song, Wilbur Madison

Year: 2020

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/2244

Thesis Macroautophagy, alpha-synuclein and dopamine neurotransmission: implications for Parkinson’s disease

Hunn, BHM · 2017 · University of Oxford - ORA · DOI

Full title: Macroautophagy, alpha-synuclein and dopamine neurotransmission: implications for Parkinson’s disease

Authors: Hunn, BHM

Year: 2017

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:0b3161d2-bca3-49da-af63-a2cc7debaa84

Thesis Investigating the effects of autophagic perturbations on mitochondrial function in Parkinson’s Disease

Ryan Barlow Patterson · 2019 · University of Oxford - ORA · DOI

Full title: Investigating the effects of autophagic perturbations on mitochondrial function in Parkinson’s Disease

Authors: Ryan Barlow Patterson

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:4142d43b-002c-4bdc-8a3e-8ce3d41b72f1

Thesis Antisense Reduction of the Protein Tau Attenuates Neuronal Hyperexcitability and Permits Clearance of Intraneuronal Tau Accumulations in vivo

DeVos, Sarah Lorraine · 2014 · Washington University in St. Louis · DOI

Full title: Antisense Reduction of the Protein Tau Attenuates Neuronal Hyperexcitability and Permits Clearance of Intraneuronal Tau Accumulations in vivo

Authors: DeVos, Sarah Lorraine

Year: 2014

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/etd/1298

Thesis Analysis of novel pathways in neurodegeneration using mouse and fly model organisms

Paton, L · 2015 · University of Oxford - ORA · DOI

Full title: Analysis of novel pathways in neurodegeneration using mouse and fly model organisms

Authors: Paton, L

Year: 2015

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:43e6bcfb-47d2-44b2-a10b-81d135ceb824

Thesis VCP: A Gatekeeper for Intracellular Proteopathic Seeding

Zhu, Jiang · 2022 · Washington University in St. Louis · DOI

Full title: VCP: A Gatekeeper for Intracellular Proteopathic Seeding

Authors: Zhu, Jiang

Year: 2022

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/2666

Thesis Mechanisms of Brain Region-Specific Amyloid-beta Deposition

Bero, Adam · 2011 · Washington University in St. Louis · DOI

Full title: Mechanisms of Brain Region-Specific Amyloid-beta Deposition

Authors: Bero, Adam

Year: 2011

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/etd/553

Thesis Loss of TREM2-dependent microgliosis in mouse models of amyloid-beta and tau pathologies reveal juxtaposed roles for reactive microglia in Alzheimerճ disease

Leyns, Cheryl Elizabeth Grace · 2018 · Washington University in St. Louis · DOI

Full title: Loss of TREM2-dependent microgliosis in mouse models of amyloid-beta and tau pathologies reveal juxtaposed roles for reactive microglia in Alzheimerճ disease

Authors: Leyns, Cheryl Elizabeth Grace

Year: 2018

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/1634

Thesis Analysing the function and dysfunction of TLDc proteins in neurological disorders

Bucknor, EMV · 2022 · University of Oxford - ORA · DOI

Full title: Analysing the function and dysfunction of TLDc proteins in neurological disorders

Authors: Bucknor, EMV

Year: 2022

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:6c249cc1-578c-49f4-917e-bee6e1c6f1b5

Thesis Unfolded protein responses in models of Motor Neuron Disease

Kwok, A · 2010 · University of Oxford - ORA · DOI

Full title: Unfolded protein responses in models of Motor Neuron Disease

Authors: Kwok, A

Year: 2010

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:2f3efba7-dce1-4521-bda6-4db8ee81094d

Thesis Network pharmacology of the MPP+ cellular model of Parkinson’s disease

Keane, H · 2015 · University of Oxford - ORA · DOI

Full title: Network pharmacology of the MPP+ cellular model of Parkinson’s disease

Authors: Keane, H

Year: 2015

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:1e18e521-c1a3-4f1b-9572-9c68e0f16c2f

Thesis Mechanisms underlying the endogenous neuroprotection of hamartin in ischaemic stroke

Hadley, GL · 2016 · University of Oxford - ORA · DOI

Full title: Mechanisms underlying the endogenous neuroprotection of hamartin in ischaemic stroke

Authors: Hadley, GL

Year: 2016

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:1560ec7f-15cb-4c2d-b55d-2ac2bc653dfd

Thesis Stem cell modelling of ⍺-synuclein aggregation and its pathology

Tanudjojo, B · 2021 · University of Oxford - ORA · DOI

Full title: Stem cell modelling of ⍺-synuclein aggregation and its pathology

Authors: Tanudjojo, B

Year: 2021

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:834ffda4-589f-4ed4-a352-be3625335b94

Thesis Towards extracellular vesicle based gene therapy for Huntington's disease

O'Loughlin, A · 2016 · University of Oxford - ORA · DOI

Full title: Towards extracellular vesicle based gene therapy for Huntington's disease

Authors: O'Loughlin, A

Year: 2016

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:d44d4535-aeb2-4bc0-bc27-15ce9ef4e37e

Thesis Molecular characterisation of autophagy deficits in a LRRK2-BAC transgenic rat model of Parkinson’s disease

Wallings, R · 2018 · University of Oxford - ORA · DOI

Full title: Molecular characterisation of autophagy deficits in a LRRK2-BAC transgenic rat model of Parkinson’s disease

Authors: Wallings, R

Year: 2018

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:7af0e93f-56cd-49cd-983d-1becc875351f

Thesis The role of alpha-synuclein oligomers in Parkinson's disease pathophysiology and biology

Roberts, R · 2015 · University of Oxford - ORA · DOI

Full title: The role of alpha-synuclein oligomers in Parkinson's disease pathophysiology and biology

Authors: Roberts, R

Year: 2015

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:e13d9429-f2cd-4764-bf8d-d139e71f7711

Thesis Targeting TFEB and TFE3 in iPSC-derived dopaminergic neurons to correct autophagic/lysosomal deficits in Parkinson's disease

McGuinness, W · 2023 · University of Oxford - ORA · DOI

Full title: Targeting TFEB and TFE3 in iPSC-derived dopaminergic neurons to correct autophagic/lysosomal deficits in Parkinson's disease

Authors: McGuinness, W

Year: 2023

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:a1d5b7f3-5f45-4aa9-94da-d11251a82f74

Thesis THE E3 UBIQUITIN LIGASE HECW1 IN NEURONAL HOMEOSTASIS

SALA, SIMONA · 2021 · Università degli Studi di Milano (AIR) · DOI

Full title: THE E3 UBIQUITIN LIGASE HECW1 IN NEURONAL HOMEOSTASIS

Authors: SALA, SIMONA

Year: 2021

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/883944

Thesis Modulation of AMPK's activity via genetic tools and food-derived compounds as a novel approach to Parkinson's disease treatment

Bobela, Wojciech Janusz · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Modulation of AMPK's activity via genetic tools and food-derived compounds as a novel approach to Parkinson's disease treatment

Authors: Bobela, Wojciech Janusz

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/125873

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BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease

Li, Yue; Zheng, Wanqing; Lu, Yangyang et al. · 2021

Full title: BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease

Authors: Li, Yue; Zheng, Wanqing; Lu, Yangyang; Zheng, Yanrong; Pan, Ling; Wu, Xiaoli; Yuan, Yang; Shen, Zhe; Ma, Shijia; Zhang, Xingxian; Wu, Jiaying; Chen, Zhong; Zhang, Xiangnan

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FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.

Zhou, Kailiang; Chen, Huanwen; Lin, Jinti et al. · 2019

Full title: FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.

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Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction.

Xu, Jianye; Zhang, Jian; Zhang, Zongpu et al. · 2021

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SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy.

Ma, Chengxiao; Zhang, Wen; Wang, Wengcong et al. · 2021

Full title: SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy.

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NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma.

Huang, Xi; Cao, Wen; Yao, Shunnan et al. · 2022

Full title: NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma.

Authors: Huang, Xi; Cao, Wen; Yao, Shunnan; Chen, Jing; Liu, Yang; Qu, Jianwei; Li, Yi; Han, Xiaoyan; He, Jingsong; Huang, He; Zhang, Enfan; Cai, Zhen

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ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

Ajoolabady, Amir; Lindholm, Dan; Ren, Jun et al. · 2022

Full title: ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

Authors: Ajoolabady, Amir; Lindholm, Dan; Ren, Jun; Praticò, Domenico

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Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways

Xie, Zhen; Zhao, Mengyuan; Yan, Chengxiang et al. · 2023

Full title: Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways

Authors: Xie, Zhen; Zhao, Mengyuan; Yan, Chengxiang; Kong, Wei; Lan, Fei; Narengaowa; Zhao, Shuxuan; Yang, Qinghu; Bai, Zhan‐Tao; Qing, Hong; Ni, Junjun

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Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death.

Depierre, Pauline; Ginet, Vanessa; Truttmann, Anita C et al. · 2024

Full title: Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death.

Authors: Depierre, Pauline; Ginet, Vanessa; Truttmann, Anita C; Puyal, Julien

DOI: https://doi.org/10.1038/s41419-024-06750-2

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CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.

Wang, Di; Li, Yongge; Chang, Weilong et al. · 2024

Full title: CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.

Authors: Wang, Di; Li, Yongge; Chang, Weilong; Feng, Meina; Yang, Yiming; Zhu, Xiuxiang; Liu, Zhibo; Fu, Yang

DOI: https://doi.org/10.1038/s41419-024-07057-y

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Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases.

Zhang, Weihuang; Li, Xiaoyu; Wang, Shujun et al. · 2020

Full title: Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases.

Authors: Zhang, Weihuang; Li, Xiaoyu; Wang, Shujun; Chen, Yanse; Liu, Huafeng

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Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.

Wang, Xin; Dong, Feng-Lin; Wang, Ying-Qiao et al. · 2023

Full title: Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.

Authors: Wang, Xin; Dong, Feng-Lin; Wang, Ying-Qiao; Wei, Hong-Long; Li, Tao; Li, Jie

DOI: https://doi.org/10.1038/s41419-023-05989-5

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Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during aging.

Liu, Rui; Cui, Juanjuan; Sun, Yating et al. · 2021

Full title: Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during aging.

Authors: Liu, Rui; Cui, Juanjuan; Sun, Yating; Xu, Wentao; Wang, Ziming; Wu, Miaomiao; Dong, Huke; Yang, Congcong; Hong, Shaocheng; Yin, Shi; Wang, Hua

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Full title: Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma.

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Full title: Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability.

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Full title: Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

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Full title: Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation

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Full title: Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuronal cells.

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Full title: Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

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Full title: 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.

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Full title: HMGB1 mediated autophagy and apoptosis in human nucleus pulposus cells; chloroquine amplified apoptosis by inhibiting autophagy.

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Full title: Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

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Full title: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures.

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Full title: The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer

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Full title: The germline-enriched Ppp1r36 promotes autophagy.

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Full title: Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin

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Full title: Role of autophagy in neurotoxic protein's clearance following post-ischemic stroke: where we are and what we know?

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Full title: Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?

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Full title: YAP promotes autophagy and progression of gliomas via upregulating HMGB1.

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Full title: CircCEMIP promotes anoikis-resistance by enhancing protective autophagy in prostate cancer cells.

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Full title: Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.

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Full title: Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy.

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Full title: Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

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Full title: Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy.

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Full title: Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.

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Full title: Exosomes: biogenesis, biologic function and clinical potential

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Full title: Quercetin improves myocardial ischemia-reperfusion injury by regulating macrophage M2 polarization through Bcl-2/Beclin-1 complex.

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Full title: PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

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Full title: Protein misfolding in neurodegenerative diseases: implications and strategies

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Full title: Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux.

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Full title: O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review).

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Full title: Knockdown of Beclin 1 inhibits vitamin K3‑induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells.

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Full title: Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion.

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Full title: Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation.

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Full title: Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma.

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Full title: Molecular mechanisms of tamoxifen-associated endometrial cancer (Review)

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Full title: Rapamycin promotes the anticancer action of dihydroartemisinin in breast cancer MDA-MB-231 cells by regulating expression of Atg7 and DAPK.

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Full title: Neurodegenerative Diseases: Regenerative Mechanisms and Novel Therapeutic Approaches

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Full title: Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies

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Full title: mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

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Full title: Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease

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Full title: Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia

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Full title: Critical Roles and Molecular Mechanisms of Chaperone-Mediated Autophagy in Infections.

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Full title: Nanoparticles: Taking a Unique Position in Medicine

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Full title: Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

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Full title: Exosome-Based Drug Delivery: Translation from Bench to Clinic

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Full title: Overview of Metformin and Neurodegeneration: A Comprehensive Review.

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Full title: Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation.

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Full title: A review on anti-cancer properties of quercetin in gastric cancer.

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Full title: Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy.

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Full title: Pterostilbene attenuates osteoarthritis progression through p53-dependent autophagy activation: evidence from network analysis and experimental validation.

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Full title: Exploring bioactive phytochemicals as ULK1 activators for enhancing cytoprotective autophagy in amyotrophic lateral sclerosis.

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Full title: The endoplasmic reticulum stress response in aging and age-related diseases

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Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.

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Full title: Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.

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Full title: Role of AMPK in autophagy.

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Full title: Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.

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Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.

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Full title: Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.

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Full title: Mechanisms and Therapeutic Targets of Depression After Intracerebral Hemorrhage.

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Arctigenin from Fructus arctii Exhibits Antiaging Effects via Autophagy Induction, Antioxidative Stress, and Increase in Telomerase Activity in Yeast.

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Full title: Arctigenin from Fructus arctii Exhibits Antiaging Effects via Autophagy Induction, Antioxidative Stress, and Increase in Telomerase Activity in Yeast.

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Procyanidin A1 from Peanut Skin Exerts Anti-Aging Effects and Attenuates Senescence via Antioxidative Stress and Autophagy Induction.

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Full title: Procyanidin A1 from Peanut Skin Exerts Anti-Aging Effects and Attenuates Senescence via Antioxidative Stress and Autophagy Induction.

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Full title: Using Zebrafish to Dissect the Interaction of Mycobacteria with the Autophagic Machinery in Macrophages.

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Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines.

Ohnishi, Kohta; Yano, Satoshi; Fujimoto, Moe et al. · 2020

Full title: Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines.

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Full title: Role of TFEB in Huntington's Disease.

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Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases.

Huang, Fu-Chen · 2024

Full title: Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases.

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The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect.

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Full title: The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect.

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Mesenchymal Stem Cell-Derived Exosomes miR-143-3p Attenuates Diabetic Kidney Disease by Enhancing Podocyte Autophagy via Bcl-2/Beclin1 Pathway.

Song, Wenze; Wang, Jiao; Guan, Lulu et al. · 2026

Full title: Mesenchymal Stem Cell-Derived Exosomes miR-143-3p Attenuates Diabetic Kidney Disease by Enhancing Podocyte Autophagy via Bcl-2/Beclin1 Pathway.

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Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy.

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Full title: Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy.

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Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lisosan G.

Bongiorni, Silvia; Catalani, Elisabetta; Arisi, Ivan et al. · 2024

Full title: Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lisosan G.

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Full title: Endogenous Mechanisms of Neuroprotection: To Boost or Not to Boost.

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Reversal of Myofibroblast Apoptosis Resistance and Collagen Deposition by Phaseoloidin-Induced Autophagy Attenuates Pulmonary Fibrosis.

Li, Siyuan; Qian, Jiazhen; Deng, Lang et al. · 2025

Full title: Reversal of Myofibroblast Apoptosis Resistance and Collagen Deposition by Phaseoloidin-Induced Autophagy Attenuates Pulmonary Fibrosis.

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Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse.

Thongchot, Suyanee; Vidoni, Chiara; Ferraresi, Alessandra et al. · 2021

Full title: Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse.

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Full title: Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

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Full title: BECLIN1: Protein Structure, Function and Regulation

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Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.

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Full title: Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.

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Full title: Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System.

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Full title: Calcium Signaling Regulates Autophagy and Apoptosis

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Full title: 14-3-3 Proteins are Regulators of Autophagy.

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Full title: Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

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Full title: The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.

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Full title: GBA Variants and Parkinson Disease: Mechanisms and Treatments

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Full title: Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficits Induced by Anesthesia/Surgery in Aged Mice.

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Full title: Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?

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Full title: Iron in Neurodegeneration – Cause or Consequence?

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Full title: Protein Quality Control by Molecular Chaperones in Neurodegeneration

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Full title: Caffeine and Parkinson’s Disease: Multiple Benefits and Emerging Mechanisms

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Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.

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Full title: Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.

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Full title: The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

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Full title: Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria.

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TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway.

Zhou, Wenjuan; Yao, Yuan; Li, Jinxing et al. · 2019

Full title: TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway.

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Full title: Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities

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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

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The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.

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Full title: The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.

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Full title: Emerging role of selective autophagy in human diseases.

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RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway.

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Full title: RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway.

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Full title: Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.

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Sun, Xiaojuan; Chen, Weidong; Wang, Yan‐Dong · 2015

Full title: β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

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Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells.

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Watt, Georgia; Karl, Tim · 2017

Full title: In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

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Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.

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Full title: Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.

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Applications of Ruthenium Complex in Tumor Diagnosis and Therapy

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Full title: Applications of Ruthenium Complex in Tumor Diagnosis and Therapy

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Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.

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Full title: Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.

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Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway.

Lin, Jianzhen; Jiao, Ao; Lv, Wu et al. · 2019

Full title: Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway.

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Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.

Chen, Yan; Liu, Qingpu; Shan, Zengfu et al. · 2019

Full title: Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.

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Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.

Wang, Dong; Guo, Haoran; Yang, Huahong et al. · 2019

Full title: Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.

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Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling.

Fang, Yuwei; Shi, Kangpei; Lu, Haining et al. · 2021

Full title: Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling.

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The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents

Zhou, Jiabei; Kang, Yu; Chen, Lu et al. · 2020

Full title: The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents

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Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.

Zhou, Feiya; Zhang, Xian; Jiang, Liangfu et al. · 2021

Full title: Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.

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Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways.

Tian, Ruimin; Wang, Pinchao; Huang, Lihua et al. · 2020

Full title: Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways.

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Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.

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Full title: Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.

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Full title: New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection.

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Full title: Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival.

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Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells.

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Full title: Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells.

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Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.

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Full title: Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy.

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Lin, Hongru; Zhang, Chen; Gao, Yehui et al. · 2024

Full title: HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans.

Authors: Lin, Hongru; Zhang, Chen; Gao, Yehui; Zhou, Yi; Ma, Botian; Jiang, Jinyun; Long, Xue; Yimamu, Nuerziya; Zhong, Kaixin; Li, Yingzi; Cui, Xianghuan; Wang, Hongbing

DOI: https://doi.org/10.3389/fphar.2024.1433030

Paper

Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stress and autophagy-mediated pyroptosis.

Wu, Fangfang; Zhang, Renkan; Meng, Weiyang et al. · 2022

Full title: Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stress and autophagy-mediated pyroptosis.

Authors: Wu, Fangfang; Zhang, Renkan; Meng, Weiyang; Liu, Lei; Tang, Yingdan; Lu, Leilei; Xia, Leilei; Zhang, Hongyu; Feng, Zhiguo; Chen, Daqing

DOI: https://doi.org/10.3389/fphar.2022.862324

Paper

Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats and palmitic acid-challenged KGN cells by modulating lipid metabolism.

Li, Tian; Wei, Yao; Jiao, Beibie et al. · 2024

Authors: Li, Tian; Wei, Yao; Jiao, Beibie; Hao, Rui; Zhou, Beibei; Bian, Xinlan; Wang, Peijuan; Zhou, Yahong; Sun, Xia; Zhang, Jian

DOI: https://doi.org/10.3389/fphar.2024.1425844

Paper

Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.

Xin, Ming; Gao, Qi; Xiang, Xindong et al. · 2022

Full title: Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.

Authors: Xin, Ming; Gao, Qi; Xiang, Xindong; Xu, Juanjuan; Jiao, Yuhan; Li, Xuan; Zhang, Xianzhen; Jia, Xiuqin

DOI: https://doi.org/10.3389/fphar.2022.890974

Paper

Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.

Hu, Jiaji; Ying, Hanglu; Yao, Jie et al. · 2021

Full title: Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy.

Authors: Hu, Jiaji; Ying, Hanglu; Yao, Jie; Yang, Longhe; Jin, Wenhui; Ma, Huabin; Li, Long; Zhao, Yufen

DOI: https://doi.org/10.3389/fphar.2021.744483

Paper

Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.

Mao, Shuai; Chen, Peipei; Li, Ting et al. · 2018

Full title: Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.

Authors: Mao, Shuai; Chen, Peipei; Li, Ting; Guo, Liheng; Zhang, Minzhou

DOI: https://doi.org/10.3389/fphys.2018.00589

Paper

Targeting autophagy: polydatin's role in inducing cell death in AML.

Fu, Ping; Luo, Qing; Wang, Chao et al. · 2024

Full title: Targeting autophagy: polydatin's role in inducing cell death in AML.

Authors: Fu, Ping; Luo, Qing; Wang, Chao; Chen, Liping; Dong, Chang; Yang, Ke; Wu, Guang

DOI: https://doi.org/10.3389/fphar.2024.1470217

Paper

Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: a review.

Ntsapi, C; Weyers, M; Chinheya, R et al. · 2025

Full title: Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: a review.

Authors: Ntsapi, C; Weyers, M; Chinheya, R; Jim, T; Matsabisa, M

DOI: https://doi.org/10.3389/fphar.2025.1748368

Paper

Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.

Shen, Fei; Zheng, Yun-Sheng; Dong, Lan et al. · 2024

Full title: Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.

Authors: Shen, Fei; Zheng, Yun-Sheng; Dong, Lan; Cao, Ziyang; Cao, Jie

DOI: https://doi.org/10.3389/fphar.2024.1500731

Paper

Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR.

Huangfu, Yaru; Yu, Xiuxian; Wan, Chengyu et al. · 2023

Full title: Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR.

Authors: Huangfu, Yaru; Yu, Xiuxian; Wan, Chengyu; Zhu, Yuda; Wei, Zeliang; Li, Fan; Wang, Yilan; Zhang, Kun; Li, Shiyi; Dong, Yuman; Li, Yangying; Niu, Hai; Xin, Guang; Huang, Wen

DOI: https://doi.org/10.3389/fphar.2023.1105726

Paper

Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer's Disease Model.

Faikoglu, Gokhan; Saygisever-Faikoglu, Kübra; Ozbasak, Hande et al. · 2025

Full title: Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer's Disease Model.

Authors: Faikoglu, Gokhan; Saygisever-Faikoglu, Kübra; Ozbasak, Hande; Ugur, Sedat Askin; Uskur, Tugce; Akkan, Ahmet Gökhan; Kelicen-Ugur, Pelin; Ozyazgan, Sibel

DOI: https://doi.org/10.7759/cureus.88449

Paper

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

Yang, Yang; Wang, Huanan; Kouadir, Mohammed et al. · 2019

Full title: Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

Authors: Yang, Yang; Wang, Huanan; Kouadir, Mohammed; Song, Houhui; Shi, Fushan

DOI: https://doi.org/10.1038/s41419-019-1413-8

Paper

Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.

Xue, Wenjing; Xu, Caili; Zhang, Kaiqi et al. · 2024

Full title: Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.

Authors: Xue, Wenjing; Xu, Caili; Zhang, Kaiqi; Cui, Lu; Huang, Xiting; Nan, Yanyang; Ju, Dianwen; Chang, Xusheng; Zhang, Xuyao

DOI: https://doi.org/10.1038/s41420-024-02167-0

Paper

A self-destructive nanosweeper that captures and clears amyloid β-peptides

Luo, Qiang; Lin, Yao‐Xin; Yang, Pei‐Pei et al. · 2018

Full title: A self-destructive nanosweeper that captures and clears amyloid β-peptides

Authors: Luo, Qiang; Lin, Yao‐Xin; Yang, Pei‐Pei; Wang, Yi; Qi, Guobin; Qiao, Zeng‐Ying; Li, Bingnan; Zhang, Kuo; Zhang, Jingping; Wang, Lei; Wang, Hao

DOI: https://doi.org/10.1038/s41467-018-04255-z

Paper

MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.

Xing, Lei; Bu, Yu; Shi, Jingqi et al. · 2025

Full title: MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.

Authors: Xing, Lei; Bu, Yu; Shi, Jingqi; Liu, Jing; Hu, Fan; Zhang, Minghua; Fan, Jiao

DOI: https://doi.org/10.1186/s12944-025-02683-7

Paper

Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy.

Tian, He; Zhao, Haosen; Mei, Xifan et al. · 2021

Full title: Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy.

Authors: Tian, He; Zhao, Haosen; Mei, Xifan; Li, Daoyong; Lin, Jiaquan; Lin, Sen; Song, Changwei

DOI: https://doi.org/10.22038/ijbms.2020.44534.10416

Paper

Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells.

Zhou, Jianhua; Li, Shengyou; Gao, Jianbo et al. · 2020

Full title: Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells.

Authors: Zhou, Jianhua; Li, Shengyou; Gao, Jianbo; Hu, Yawei; Chen, Shaochu; Luo, Xinle; Zhang, Hao; Luo, Zhuojing; Huang, Jinghui

DOI: https://doi.org/10.3389/fncel.2020.00143

Paper

Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum.

Luan, Yanan; Ren, Xiangpeng; Zheng, Wu et al. · 2018

Full title: Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum.

Authors: Luan, Yanan; Ren, Xiangpeng; Zheng, Wu; Zeng, Zhenhai; Guo, Yingzi; Hou, Zhidong; Guo, Wei; Chen, Xingjun; Li, Fei; Chen, Jiang-Fan

DOI: https://doi.org/10.3389/fnins.2018.00301

Paper

Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model.

Liu, Yongda; Wang, Shuang; Wang, Zhibin et al. · 2020

Full title: Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model.

Authors: Liu, Yongda; Wang, Shuang; Wang, Zhibin; Ding, Mengmeng; Li, Xingyue; Guo, Jiao; Han, Guang; Zhao, Ping

DOI: https://doi.org/10.3389/fnins.2020.00090

Paper

Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway.

Zhao, Yuan; Feng, Xiujing; Li, Bei et al. · 2020

Full title: Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway.

Authors: Zhao, Yuan; Feng, Xiujing; Li, Bei; Sha, Jichen; Wang, Chaoran; Yang, Tianyuan; Cui, Hailin; Fan, Honggang

DOI: https://doi.org/10.3389/fphar.2020.00128

Paper

PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease

Long, Hui‐Zhi; Cheng, Yan; Zhou, Ziwei et al. · 2021

Full title: PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease

Authors: Long, Hui‐Zhi; Cheng, Yan; Zhou, Ziwei; Luo, Hongyu; Wen, Dan‐Dan; Gao, Lichen

DOI: https://doi.org/10.3389/fphar.2021.648636

Paper

Artesunate Exerts Organ- and Tissue-Protective Effects by Regulating Oxidative Stress, Inflammation, Autophagy, Apoptosis, and Fibrosis: A Review of Evidence and Mechanisms.

Zhu, Mingtao; Wang, Yu; Han, Jianwei et al. · 2024

Full title: Artesunate Exerts Organ- and Tissue-Protective Effects by Regulating Oxidative Stress, Inflammation, Autophagy, Apoptosis, and Fibrosis: A Review of Evidence and Mechanisms.

Authors: Zhu, Mingtao; Wang, Yu; Han, Jianwei; Sun, Yanping; Wang, Shuang; Yang, Bingyou; Wang, Qiuhong; Kuang, Haixue

DOI: https://doi.org/10.3390/antiox13060686

Paper

Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.

Zhang, Yongjie; Fan, Tingjun · 2025

Full title: Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.

Authors: Zhang, Yongjie; Fan, Tingjun

DOI: https://doi.org/10.3390/antiox14111381

Paper

Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

Reddy, P. Hemachandra; Oliver, Darryll · 2019

Full title: Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

Authors: Reddy, P. Hemachandra; Oliver, Darryll

DOI: https://doi.org/10.3390/cells8050488

Paper

Ketogenic Diet in Alzheimer’s Disease

Rusek, Marta; Pluta, Ryszard; Ułamek-Kozioł, Marzena et al. · 2019

Full title: Ketogenic Diet in Alzheimer’s Disease

Authors: Rusek, Marta; Pluta, Ryszard; Ułamek-Kozioł, Marzena; Czuczwar, Stanisław J.

DOI: https://doi.org/10.3390/ijms20163892

Paper

LINC00470 represses cell autophagy and cisplatin sensitivity of glioma via suppressing PTEN expression.

Chen, Biyin; Wang, Wenwu; Lin, Fangfeng et al. · 2023

Full title: LINC00470 represses cell autophagy and cisplatin sensitivity of glioma via suppressing PTEN expression.

Authors: Chen, Biyin; Wang, Wenwu; Lin, Fangfeng; Shi, Shuping; Ou, Shunjie; Yu, Yunqiu

DOI: https://doi.org/10.5114/fn.2023.125327

Thesis

The role of PLK2 in modulating alpha-synuclein degradation dynamics in Parkinson's disease

Zhang, Weijian · 2016

Full title: The role of PLK2 in modulating alpha-synuclein degradation dynamics in Parkinson's disease

Authors: Zhang, Weijian

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-100408

Thesis

A study on the role of p32 in mitophagy

Zhang, Jin · 2017

Full title: A study on the role of p32 in mitophagy

Authors: Zhang, Jin

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-104819

Thesis

Autophagosome dynamics in Huntington's disease

Li, Chun Hei · 2020

Full title: Autophagosome dynamics in Huntington's disease

Authors: Li, Chun Hei

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-110546

Thesis

Mitochondrial and autophagosomes' transport defect in Q175 knock-in mouse model of huntington's disease

Zhang, Min · 2017

Full title: Mitochondrial and autophagosomes' transport defect in Q175 knock-in mouse model of huntington's disease

Authors: Zhang, Min

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-105666

Thesis

Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Liu, Han-Qing; An, Ya-Wen; Hu, A-Zhen et al. · 2019

Full title: Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Authors: Liu, Han-Qing; An, Ya-Wen; Hu, A-Zhen; Li, Ming-Hua; Wu, Jue-Lian; Liu, Li; Shi, Yu; Cui, Guang-Hui; Chen, Yun

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-95911

Thesis

NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson's disease models

Valencia-Alarcón, Eva P.; Duret, Lou C.; Kobayashi, Emi et al. · 2025

Full title: NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson's disease models

Authors: Valencia-Alarcón, Eva P.; Duret, Lou C.; Kobayashi, Emi; Cattaneo, O; Schneider, Bernard L.; Nagoshi, Emi

DOI: https://infoscience.epfl.ch/handle/20.500.14299/254943

Thesis

Tau accumulation in degradative organelles is associated to lysosomal stress

Piovesana, Ester; Magrin, Claudia; Ciccaldo, Matteo et al. · 2024

Full title: Tau accumulation in degradative organelles is associated to lysosomal stress

Authors: Piovesana, Ester; Magrin, Claudia; Ciccaldo, Matteo; Sola, Martina; Bellotto, Manolo; Molinari, Maurizio; Papin, Stephanie; Paganetti, Paolo

DOI: https://infoscience.epfl.ch/handle/20.500.14299/204251

Thesis

A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models

Ciccaldo, Matteo; Pérez‐Carmona, Natàlia; Piovesana, Ester et al. · 2025

Full title: A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250562

Thesis

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Balana, Aaron T.; Mahul-Mellier, Anne-Laure; Nguyen, Binh A. et al. · 2024

Full title: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

DOI: https://infoscience.epfl.ch/handle/20.500.14299/205548

Thesis

Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Oueslati, Abid; Schneider, Bernard L.; Aebischer, Patrick et al. · 2013

Full title: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Authors: Oueslati, Abid; Schneider, Bernard L.; Aebischer, Patrick; Lashuel, Hilal A.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/94836

Thesis

Measurement of autophagy flux in the nervous system in vivo

Castillo, K.; Valenzuela, V.; Matus, S. et al. · 2014

Full title: Measurement of autophagy flux in the nervous system in vivo

Authors: Castillo, K.; Valenzuela, V.; Matus, S.; Nassif, M.; Onate, M.; Fuentealba, Y.; Encina, G.; Irrazabal, T.; Parsons, G.; Court, F. A.; Schneider, B. L.; Armentano, D.; Hetz, C.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/99328

Thesis

GTPase Activity Plays a Key Role in the Pathobiology of LRRK2

Xiong, Yulan; Coombes, Candice E.; Kilaru, Austin et al. · 2011

Full title: GTPase Activity Plays a Key Role in the Pathobiology of LRRK2

Authors: Xiong, Yulan; Coombes, Candice E.; Kilaru, Austin; Li, Xiaojie; Gitler, Aaron D.; Bowers, William J.; Dawson, Valina L.; Dawson, Ted M.; Moore, Darren J.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/75538

Thesis

Mechanisms of LRRK2-Mediated Neurodegeneration

Tsika, Elpida; Moore, Darren J. · 2012

Full title: Mechanisms of LRRK2-Mediated Neurodegeneration

Authors: Tsika, Elpida; Moore, Darren J.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80762

Thesis

PGC-1 alpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein

Ciron, Carine; Zheng, Lu; Bobela, Wojciech et al. · 2015

Full title: PGC-1 alpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein

Authors: Ciron, Carine; Zheng, Lu; Bobela, Wojciech; Knott, Graham W.; Leone, Teresa C.; Kelly, Daniel P.; Schneider, Bernard L.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/120979

Thesis

AUTOPHAGY AND NEURODEGENERATION: DISCOVERING CRITICAL INSIGHTS AND INNOVATIVE THERAPEUTIC STRATEGIES USING A NOVEL HUMAN NEURON MODEL OF BPAN

Zaveri, Hetavi · 2024

Full title: AUTOPHAGY AND NEURODEGENERATION: DISCOVERING CRITICAL INSIGHTS AND INNOVATIVE THERAPEUTIC STRATEGIES USING A NOVEL HUMAN NEURON MODEL OF BPAN

Authors: Zaveri, Hetavi

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/69818

Thesis

The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

de Oliveira, Rita Machado; Vicente Miranda, Hugo; Francelle, Laetitia et al. · 2017

Full title: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

DOI: https://infoscience.epfl.ch/handle/20.500.14299/134993

Thesis

An Investigation into Mitigating Proteotoxicity In Vitro and In Vivo

Shrivastava, Gautam Anand · 2018

Full title: An Investigation into Mitigating Proteotoxicity In Vitro and In Vivo

Authors: Shrivastava, Gautam Anand

DOI: http://jhir.library.jhu.edu/handle/1774.2/44605

Thesis

Reduction of SOD Aggregation Using In Vitro and In Vivo ALS Models

Shea, John · 2019

Full title: Reduction of SOD Aggregation Using In Vitro and In Vivo ALS Models

Authors: Shea, John

DOI: http://jhir.library.jhu.edu/handle/1774.2/60328

Thesis

Novel mechanisms of autophagy-lysosome dysfunction in GBA1 Parkinson disease

Tewari, Shailvi · 2025

Full title: Novel mechanisms of autophagy-lysosome dysfunction in GBA1 Parkinson disease

Authors: Tewari, Shailvi

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70991

Thesis

Repurposing proteostasis-modifying drugs to prevent or treat age-related dementia: A systematic review

Heard, DS; Tuttle, CSL; Lautenschlager, NT et al. · 2020

Full title: Repurposing proteostasis-modifying drugs to prevent or treat age-related dementia: A systematic review

Authors: Heard, DS; Tuttle, CSL; Lautenschlager, NT; Maier, AB

DOI: https://hdl.handle.net/11343/253273

Thesis

Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

Moujalled, D; White, AR · 2018

Full title: Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

Authors: Moujalled, D; White, AR

DOI: https://hdl.handle.net/11343/216653

Thesis

Natural Products as Promising Drug Candidates for the Treatment of Alzheimer's Disease: Molecular Mechanism Aspect

Ansari, N; Khodagholi, F · 2020

Full title: Natural Products as Promising Drug Candidates for the Treatment of Alzheimer's Disease: Molecular Mechanism Aspect

Authors: Ansari, N; Khodagholi, F

DOI: https://hdl.handle.net/11343/251130

Thesis

Trehalose improves traumatic brain injury-induced cognitive impairment

Portbury, SD; Hare, DJ; Finkelstein, DI et al. · 2020

Full title: Trehalose improves traumatic brain injury-induced cognitive impairment

Authors: Portbury, SD; Hare, DJ; Finkelstein, DI; Adlard, PA

DOI: https://hdl.handle.net/11343/254931

Thesis

Effects of Resveratrol and Morin on Insoluble Tau in Tau Transgenic Mice.

Yu, KC; Kwan, P; Cheung, SKK et al. · 2020

Full title: Effects of Resveratrol and Morin on Insoluble Tau in Tau Transgenic Mice.

Authors: Yu, KC; Kwan, P; Cheung, SKK; Ho, A; Baum, L

DOI: https://hdl.handle.net/11343/250317

Thesis

Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression

Perera, ND; Sheean, RK; Lau, CL et al. · 2020

Full title: Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression

Authors: Perera, ND; Sheean, RK; Lau, CL; Shin, YS; Beart, PM; Horne, MK; Turner, BJ

DOI: https://hdl.handle.net/11343/257156

Thesis

Molecular mechanisms of cell death in neurological diseases

Moujalled, D; Strasser, A; Liddell, JR · 2021

Full title: Molecular mechanisms of cell death in neurological diseases

Authors: Moujalled, D; Strasser, A; Liddell, JR

DOI: https://hdl.handle.net/11343/280998

Thesis

Iron promotes the clearance of α-synuclein: An Editorial for 'H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity” on page 177

Tuo, QZ; Lei, P · 2021

Authors: Tuo, QZ; Lei, P

DOI: https://hdl.handle.net/11343/276111

Thesis

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Fox, JH; Connor, T; Chopra, V et al. · 2021

Authors: Fox, JH; Connor, T; Chopra, V; Dorsey, K; Kama, JA; Bleckmann, D; Betschart, C; Hoyer, D; Frentzel, S; Difiglia, M; Paganetti, P; Hersch, SM

DOI: https://hdl.handle.net/11343/264755

Thesis

Inhibition of bioenergetics provides novel insights into recruitment of PINK1-dependent neuronal mitophagy

Shin, YS; Ryall, JG; Britto, JM et al. · 2021

Full title: Inhibition of bioenergetics provides novel insights into recruitment of PINK1-dependent neuronal mitophagy

Authors: Shin, YS; Ryall, JG; Britto, JM; Lau, CL; Devenish, RJ; Nagley, P; Beart, PM

DOI: https://hdl.handle.net/11343/285442

Thesis

Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Corti, O; Blomgren, K; Poletti, A et al. · 2021

Full title: Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

Authors: Corti, O; Blomgren, K; Poletti, A; Beart, PM

DOI: https://hdl.handle.net/11343/274135

Thesis

Étude de l’effet neuro-protecteur de polyphénols issus de la Pomme-Grenade ainsi que de leurs dérivés métaboliques

Bretonneau, Constantin · 2022

Full title: Étude de l’effet neuro-protecteur de polyphénols issus de la Pomme-Grenade ainsi que de leurs dérivés métaboliques

Authors: Bretonneau, Constantin

DOI: http://hdl.handle.net/1866/26205

Thesis

Autophagic activity in neuronal cell death.

Button, Robert W; Luo, Shouqing; Rubinsztein, David C · 2015

Full title: Autophagic activity in neuronal cell death.

Authors: Button, Robert W; Luo, Shouqing; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/248524

Thesis

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Underwood, Benjamin R; Imarisio, Sara; Fleming, Angeleen et al. · 2018

Full title: Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

DOI: https://www.repository.cam.ac.uk/handle/1810/270325

Thesis

Autophagy and neurodegeneration

Frake, Rebecca A; Ricketts, Thomas; Menzies, Fiona M et al. · 2015

Full title: Autophagy and neurodegeneration

Authors: Frake, Rebecca A; Ricketts, Thomas; Menzies, Fiona M; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/252949

Thesis

Decanoato de nandrolona e AMPK modulam a macroautofagia e bioenergética cerebral no envelhecimento

Strogulski, Nathan Ryzewski · 2019

Full title: Decanoato de nandrolona e AMPK modulam a macroautofagia e bioenergética cerebral no envelhecimento

Authors: Strogulski, Nathan Ryzewski

DOI: http://hdl.handle.net/10183/193629

Thesis

Zebrafish as a model to understand autophagy and its role in neurological disease.

Fleming, Angeleen; Rubinsztein, David C · 2018

Full title: Zebrafish as a model to understand autophagy and its role in neurological disease.

Authors: Fleming, Angeleen; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/270333

Thesis

Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.

Willén, Katarina; Edgar, James R; Hasegawa, Takafumi et al. · 2017

Full title: Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.

Authors: Willén, Katarina; Edgar, James R; Hasegawa, Takafumi; Tanaka, Nobuyuki; Futter, Clare E; Gouras, Gunnar K

DOI: https://www.repository.cam.ac.uk/handle/1810/270155

Thesis

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

Menzies, FM; Garcia-Arencibia, M; Imarisio, S et al. · 2014

Full title: Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

Authors: Menzies, FM; Garcia-Arencibia, M; Imarisio, S; O'Sullivan, NC; Ricketts, T; Kent, BA; Rao, MV; Lam, W; Green-Thompson, ZW; Nixon, RA; Saksida, LM; Bussey, TJ; O'Kane, CJ; Rubinsztein, DC

DOI: https://www.repository.cam.ac.uk/handle/1810/246151

Thesis

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A; Schlotawa, L; Fleming, A et al. · 2017

Full title: A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Authors: Lopez, A; Schlotawa, L; Fleming, A; Rubinsztein, DC

DOI: https://www.repository.cam.ac.uk/handle/1810/262885

Thesis

Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.

Hung, Christy OY; Livesey, Frederick J · 2019

Full title: Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.

Authors: Hung, Christy OY; Livesey, Frederick J

DOI: https://www.repository.cam.ac.uk/handle/1810/287623

Thesis

Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy.

Nehammer, Camilla; Ejlerskov, Patrick; Gopal, Sandeep et al. · 2019

Full title: Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy.

Authors: Nehammer, Camilla; Ejlerskov, Patrick; Gopal, Sandeep; Handley, Ava; Ng, Leelee; Moreira, Pedro; Lee, Huikyong; Issazadeh-Navikas, Shohreh; Rubinsztein, David C; Pocock, Roger

DOI: https://www.repository.cam.ac.uk/handle/1810/299676

Thesis

Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.

Kruppa, Antonina J; Ott, Stanislav; Chandraratna, Dhia S et al. · 2018

Full title: Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.

DOI: https://www.repository.cam.ac.uk/handle/1810/275918

Thesis

Prions: generation and spread versus neurotoxicity.

Halliday, Mark; Radford, Helois; Mallucci, Giovanna R · 2019

Full title: Prions: generation and spread versus neurotoxicity.

Authors: Halliday, Mark; Radford, Helois; Mallucci, Giovanna R

DOI: https://www.repository.cam.ac.uk/handle/1810/294751

Thesis

Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases.

Ejlerskov, Patrick; Ashkenazi, Avraham; Rubinsztein, David C · 2018

Full title: Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases.

Authors: Ejlerskov, Patrick; Ashkenazi, Avraham; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/277634

Thesis

Autophagy in Childhood Neurological Disorders

Rubinsztein, DC; Zhu, Ye; Runwal, Gautam et al. · 2018

Full title: Autophagy in Childhood Neurological Disorders

Authors: Rubinsztein, DC; Zhu, Ye; Runwal, Gautam; Obrocki, Pawel

DOI: https://www.repository.cam.ac.uk/handle/1810/286379

Thesis

Autophagy in Neuronal Development and Plasticity.

Fleming, Angeleen; Rubinsztein, David C · 2020

Full title: Autophagy in Neuronal Development and Plasticity.

Authors: Fleming, Angeleen; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/307968

Thesis

Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases.

Djajadikerta, Alvin; Keshri, Swati; Pavel, Mariana et al. · 2019

Full title: Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases.

Authors: Djajadikerta, Alvin; Keshri, Swati; Pavel, Mariana; Prestil, Ryan; Ryan, Laura; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/299796

Thesis

Mendelian neurodegenerative disease genes involved in autophagy

Stamatakou, Eleanna; Wróbel, Lidia; Hill, Sandra Malmgren et al. · 2020

Full title: Mendelian neurodegenerative disease genes involved in autophagy

DOI: https://www.repository.cam.ac.uk/handle/1810/306793

Thesis

Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease.

Thackray, Alana M; Lam, Brian; Shahira Binti Ab Razak, Anisa et al. · 2020

Full title: Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease.

Authors: Thackray, Alana M; Lam, Brian; Shahira Binti Ab Razak, Anisa; Yeo, Giles; Bujdoso, Raymond

DOI: https://www.repository.cam.ac.uk/handle/1810/304498

Thesis

Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

Szebényi, Kornélia; Wenger, Léa MD; Sun, Yu et al. · 2021

Full title: Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

Authors: Szebényi, Kornélia; Wenger, Léa MD; Sun, Yu; Dunn, Alexander WE; Limegrover, Colleen A; Gibbons, George M; Conci, Elena; Paulsen, Ole; Mierau, Susanna B; Balmus, Gabriel; Lakatos, András

DOI: https://www.repository.cam.ac.uk/handle/1810/327125

Thesis

The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy.

Festa, Beatrice Paola; Barbosa, Antonio Daniel; Rob, Matea et al. · 2021

Full title: The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy.

Authors: Festa, Beatrice Paola; Barbosa, Antonio Daniel; Rob, Matea; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/325343

Thesis

Huntingtin-lowering strategies for Huntington's disease.

Barker, Roger A; Fujimaki, Motoki; Rogers, Priya et al. · 2020

Full title: Huntingtin-lowering strategies for Huntington's disease.

Authors: Barker, Roger A; Fujimaki, Motoki; Rogers, Priya; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/308624

Thesis

Gene and Cell-Based Therapies for Parkinson’s Disease: Where Are We?

Buttery, Philip C.; Barker, Roger A. · 2021

Full title: Gene and Cell-Based Therapies for Parkinson’s Disease: Where Are We?

Authors: Buttery, Philip C.; Barker, Roger A.

DOI: https://www.repository.cam.ac.uk/handle/1810/317024

Thesis

L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.

Castejón-Vega, Beatriz; Rubio, Alejandro; Pérez-Pulido, Antonio J et al. · 2022

Full title: L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.

DOI: https://www.repository.cam.ac.uk/handle/1810/332448

Thesis

Breakthroughs and bottlenecks in autophagy research.

Mizushima, Noboru; White, Eileen; Rubinsztein, David C · 2021

Full title: Breakthroughs and bottlenecks in autophagy research.

Authors: Mizushima, Noboru; White, Eileen; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/325128

Thesis

Vinexin contributes to autophagic decline in brain ageing across species

Rubinsztein, David; Park, So Jung; Frake, Rebecca et al. · 2022

Full title: Vinexin contributes to autophagic decline in brain ageing across species

Authors: Rubinsztein, David; Park, So Jung; Frake, Rebecca; Karabiyik, Cansu; Son, Sung Min; Siddiqi, Farah; Bento, Carla; Sterk, Peter; Vicinanza, Mariella

DOI: https://www.repository.cam.ac.uk/handle/1810/336109

Thesis

Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

Runfola, Massimiliano; Perni, Michele; Yang, Xiaoting et al. · 2022

Full title: Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

DOI: https://www.repository.cam.ac.uk/handle/1810/332059

Thesis

SMER28 binding to VCP/p97 enhances both autophagic and proteasomal neurotoxic protein clearance.

Wrobel, Lidia; Hill, Sandra M; Rubinsztein, David C · 2022

Full title: SMER28 binding to VCP/p97 enhances both autophagic and proteasomal neurotoxic protein clearance.

Authors: Wrobel, Lidia; Hill, Sandra M; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/340353

Thesis

A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo

Lopez, Ana; Gorb, Alena; Palha, Nuno et al. · 2022

Full title: A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo

Authors: Lopez, Ana; Gorb, Alena; Palha, Nuno; Fleming, Angeleen; Rubinsztein, David

DOI: https://www.repository.cam.ac.uk/handle/1810/337164

Thesis

Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling.

Park, So Jung; Frake, Rebecca A; Rubinsztein, David C · 2022

Full title: Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling.

Authors: Park, So Jung; Frake, Rebecca A; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/339011

Thesis

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Mauri, Sofia; Bernardo, Greta; Martinez, Aitor et al. · 2023

Full title: USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Authors: Mauri, Sofia; Bernardo, Greta; Martinez, Aitor; Favaro, Mariavittoria; Trevisan, Marta; Cobraiville, Gael; Fillet, Marianne; Caicci, Federico; Whitworth, Alexander J; Ziviani, Elena

DOI: https://www.repository.cam.ac.uk/handle/1810/350221

Thesis

Trial to assess the tolerability of using felodipine to upregulate autophagy as a treatment of Huntington’s disease (FELL-HD): a phase II, single-centre, open-label, dose-finding trial protocol

Andresen, Katie; Cutting, Emma; Apostolopoulos, Dimitrios et al. · 2024

DOI: https://www.repository.cam.ac.uk/handle/1810/373052

Thesis

The autophagy of stress granules.

Ryan, Laura; Rubinsztein, David C · 2023

Full title: The autophagy of stress granules.

Authors: Ryan, Laura; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/360939

Thesis

How does autophagy impact neurological function?

Fleming, Angeleen; Lopez, Ana; Rob, Matea et al. · 2025

Full title: How does autophagy impact neurological function?

Authors: Fleming, Angeleen; Lopez, Ana; Rob, Matea; Ramakrishna, Sarayu; Park, So Jung; Li, Xinyi; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/384309

Thesis

Targeting Protein Aggregation in ALS.

Perni, Michele; Mannini, Benedetta · 2024

Full title: Targeting Protein Aggregation in ALS.

Authors: Perni, Michele; Mannini, Benedetta

DOI: https://www.repository.cam.ac.uk/handle/1810/375930

Thesis

A53T alpha-synuclein induces mitophagy through MAM-induced fission and reduced impairment of LC3B to promote alpha-synuclein degradation

Humphries, Kayla · 2017

Full title: A53T alpha-synuclein induces mitophagy through MAM-induced fission and reduced impairment of LC3B to promote alpha-synuclein degradation

Authors: Humphries, Kayla

DOI: http://hdl.handle.net/10214/12113

Thesis

Investigating The Role Of LC3B In The Seeding Of Alpha-synuclein In Parkinson’s Disease Model Systems

Porte-Trachsel, Natalie · 2023

Full title: Investigating The Role Of LC3B In The Seeding Of Alpha-synuclein In Parkinson’s Disease Model Systems

Authors: Porte-Trachsel, Natalie

DOI: https://hdl.handle.net/10214/27355

Thesis

RATIONAL DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETED AGAINST NEURODEGENERATIVE PROCESSES AND DISEASES

GORNATI, DAVIDE · 2019

Full title: RATIONAL DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETED AGAINST NEURODEGENERATIVE PROCESSES AND DISEASES

Authors: GORNATI, DAVIDE

DOI: http://hdl.handle.net/2434/606993

Thesis

Autophagy enhancement as a target for mood stabilizing drugs.

Poquette, Chelsey Hannah · 2011

Full title: Autophagy enhancement as a target for mood stabilizing drugs.

Authors: Poquette, Chelsey Hannah

DOI: http://purl.umn.edu/102458

Thesis

Spermidine Protects Mitochondria Against Amyloid-β Oligomers

Mosca, Drake · 2025

Full title: Spermidine Protects Mitochondria Against Amyloid-β Oligomers

Authors: Mosca, Drake

DOI: https://hdl.handle.net/10214/28800

Thesis

A Drug Cocktail of Rapamycin, Acarbose, and Phenylbutyrate Enhances Resilience to an Early-Stage Model of Alzheimer’s Disease

Wezeman, Jackson · 2024

Full title: A Drug Cocktail of Rapamycin, Acarbose, and Phenylbutyrate Enhances Resilience to an Early-Stage Model of Alzheimer’s Disease

Authors: Wezeman, Jackson

DOI: http://hdl.handle.net/1773/51069

Thesis

Autophagy, or not to be: The delicate balance of cellular self-digestion in neurons and neurodegeneration

Lassen, Amy Denise · 2013

Full title: Autophagy, or not to be: The delicate balance of cellular self-digestion in neurons and neurodegeneration

Authors: Lassen, Amy Denise

DOI: http://hdl.handle.net/1773/22428

Thesis

Chaperone-mediated autophagy : roles in disease and aging

Cuervo, Ana Maria; Wong, Esther · 2015

Full title: Chaperone-mediated autophagy : roles in disease and aging

Authors: Cuervo, Ana Maria; Wong, Esther

DOI: https://hdl.handle.net/10356/103863

Thesis

Molecular Strategies to Target Protein Aggregation in Huntington's Disease

Jarosińska, Olga D; Rüdiger, Stefan G D · 2021

Full title: Molecular Strategies to Target Protein Aggregation in Huntington's Disease

Authors: Jarosińska, Olga D; Rüdiger, Stefan G D

DOI: https://dspace.library.uu.nl/handle/1874/425192

Thesis

Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Burk, Katja; Pasterkamp, R. Jeroen · 2019

Full title: Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Authors: Burk, Katja; Pasterkamp, R. Jeroen

DOI: https://dspace.library.uu.nl/handle/1874/391830

Thesis

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Esselens, C.; Oorschot, V.; Baert, V. et al. · 2004

Full title: Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Authors: Esselens, C.; Oorschot, V.; Baert, V.; Raemaekers, T.; Spittaels, K.; Serneels, L.; Zheng, H.; Saftig, P.; Strooper, B. de; Klumperman, J.; Annaert, W.

DOI: https://dspace.library.uu.nl/handle/1874/12363

Thesis

Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS

Salomon-Zimri, Shiran; Pushett, Avital; Russek-Blum, Niva et al. · 2023

Full title: Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS

DOI: https://dspace.library.uu.nl/handle/1874/455596

Thesis

Probing aggrephagy using chemically-induced protein aggregates

Janssen, Anne F J; Katrukha, Eugene A; van Straaten, Wendy et al. · 2018

Full title: Probing aggrephagy using chemically-induced protein aggregates

Authors: Janssen, Anne F J; Katrukha, Eugene A; van Straaten, Wendy; Verlhac, Pauline; Reggiori, Fulvio; Kapitein, Lukas C

DOI: https://dspace.library.uu.nl/handle/1874/376052

Thesis

Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor et al. · 2017

Full title: Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

Authors: Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor; Pereira de Almeida, Luís; Cavadas, Cláudia; Guarente, Leonard Pershing

DOI: http://hdl.handle.net/1721.1/106599

Thesis

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Kuo, Szu-Yu; Castoreno, Adam B.; Aldrich, Leslie N. et al. · 2016

Full title: Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

DOI: http://hdl.handle.net/1721.1/101110

Thesis

How do protein aggregates escape quality control in neurodegeneration?

Koopman, Margreet B.; Ferrari, Luca; Rüdiger, Stefan G.D. · 2022

Full title: How do protein aggregates escape quality control in neurodegeneration?

Authors: Koopman, Margreet B.; Ferrari, Luca; Rüdiger, Stefan G.D.

DOI: https://dspace.library.uu.nl/handle/1874/426498

Thesis

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph et al. · 2018

Full title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

DOI: http://hdl.handle.net/1721.1/117502

Thesis

A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Graeff, Johannes; Kahn, Martin; Samiei, Alireza et al. · 2017

Full title: A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Authors: Graeff, Johannes; Kahn, Martin; Samiei, Alireza; Gao, Jun; Ota, Kristie; Rei, Damien; Tsai, Li-Huei

DOI: http://hdl.handle.net/1721.1/112704

Thesis

IKKβ slows Huntington’s disease progression in R6/1 mice

Ochaba, Joseph; Fote, Gianna; Kachemov, Marketta et al. · 2020

Full title: IKKβ slows Huntington’s disease progression in R6/1 mice

DOI: https://hdl.handle.net/1721.1/126076

Thesis

Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Tardiff, Daniel F.; Lindquist, Susan · 2016

Full title: Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Authors: Tardiff, Daniel F.; Lindquist, Susan

DOI: http://hdl.handle.net/1721.1/101272

Thesis

Development and Screening of Contrast Agents for In Vivo Imaging of Parkinson’s Disease

Neal, Krista L.; Shakerdge, Naomi B.; Hou, Steven S. et al. · 2016

Full title: Development and Screening of Contrast Agents for In Vivo Imaging of Parkinson’s Disease

Authors: Neal, Krista L.; Shakerdge, Naomi B.; Hou, Steven S.; Klunk, William E.; Mathis, Chester A.; McLean, Pamela J.; Bacskai, Brian J.; Nesterov, Evgueni; Swager, Timothy M

DOI: http://hdl.handle.net/1721.1/104658

Thesis

Genome-wide genetic screening in the mammalian CNS

Wertz, Mary H.; Heiman, Myriam · 2020

Full title: Genome-wide genetic screening in the mammalian CNS

Authors: Wertz, Mary H.; Heiman, Myriam

DOI: https://hdl.handle.net/1721.1/124812

Thesis

Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease

Sarkar, Sovan; Carroll, Bernadette; Buganim, Yosef et al. · 2014

Full title: Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease

DOI: http://hdl.handle.net/1721.1/90306

Thesis

Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

Treat, Lisa H.; Raymond, Scott Bruce; Bacskai, Brian J. et al. · 2010

Full title: Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

Authors: Treat, Lisa H.; Raymond, Scott Bruce; Bacskai, Brian J.; Hynynen, Kullervo; McDannold, Nathan J.; Dewey, Jonathan D.

DOI: http://hdl.handle.net/1721.1/55365

Thesis

High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Wu, Chaohong; Hong, Pengyu; Schulte, Joost et al. · 2012

Full title: High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Authors: Wu, Chaohong; Hong, Pengyu; Schulte, Joost; Sepp, Katharine J.; Littleton, J. Troy

DOI: http://hdl.handle.net/1721.1/69109

Thesis

Modelling Neurodegeneration in Saccharomyces Cerevisiae: Why Cook with Baker's Yeast?

Khurana, Vikram; Lindquist, Susan · 2012

Full title: Modelling Neurodegeneration in Saccharomyces Cerevisiae: Why Cook with Baker's Yeast?

Authors: Khurana, Vikram; Lindquist, Susan

DOI: http://hdl.handle.net/1721.1/69914

Thesis

Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol

Svensson, Jonas E.; Bolin, Martin; Thor, Daniel et al. · 2024

Full title: Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol

DOI: https://hdl.handle.net/1721.1/154090

Thesis

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

Wertz, Mary H; Mitchem, Mollie R; Pineda, S Sebastian et al. · 2021

Full title: Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

DOI: https://hdl.handle.net/1721.1/136278

Thesis

Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, Joseph; Csikos, George; Zheng, Shuqiu et al. · 2015

Full title: Potential function for the Huntingtin protein as a scaffold for selective autophagy

DOI: http://hdl.handle.net/1721.1/97246

Thesis

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

· 2024

Full title: NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

DOI: https://hdl.handle.net/1721.1/156897

Thesis

SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

Donmez Yalcin, Gizem; Arun, Anirudh; Chung, Chee Yeun et al. · 2012

Full title: SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

Authors: Donmez Yalcin, Gizem; Arun, Anirudh; Chung, Chee Yeun; McLean, Pamela J.; Lindquist, Susan; Guarente, Leonard Pershing

DOI: http://hdl.handle.net/1721.1/72526

Thesis

Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

Maetzel, Dorothea; Sarkar, Sovan; Wang, Haoyi et al. · 2015

Full title: Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

Authors: Maetzel, Dorothea; Sarkar, Sovan; Wang, Haoyi; Abi-Mosleh, Lina; Xu, Ping; Gao, Qing; Mitalipova, Maisam; Jaenisch, Rudolf; Cheng, Albert Wu

DOI: http://hdl.handle.net/1721.1/96366

Thesis

Wallerian Degeneration Slow mutation does not alter the amyloid pathology of Alzheimer's disease

Shih, Ann Yu-Jung · 2008

Full title: Wallerian Degeneration Slow mutation does not alter the amyloid pathology of Alzheimer's disease

Authors: Shih, Ann Yu-Jung

DOI: https://escholarship.org/uc/item/0pq0c761

Thesis

Function of Protein Kinase RNA-like Endoplasmic Reticulum Kinase in regulating tau protein aggregation in Alzheimer’s Disease and Progressive Supranuclear Palsy

Xu, Ke · 2021

Full title: Function of Protein Kinase RNA-like Endoplasmic Reticulum Kinase in regulating tau protein aggregation in Alzheimer’s Disease and Progressive Supranuclear Palsy

Authors: Xu, Ke

DOI: https://escholarship.org/uc/item/0ng89469

Thesis

Lysosomal Leakage of Cathepsin B in Alzheimer's Disease and Related Neurodegenerative Brain Disorders

Ito, Gen · 2021

Full title: Lysosomal Leakage of Cathepsin B in Alzheimer's Disease and Related Neurodegenerative Brain Disorders

Authors: Ito, Gen

DOI: https://escholarship.org/uc/item/4hr292c1

Thesis

Identification of cellular mechanisms that control α-synuclein aggregation using a genome-wide CRISPR-based functional genomics screen

See, Stephanie Kum-Yin · 2020

Full title: Identification of cellular mechanisms that control α-synuclein aggregation using a genome-wide CRISPR-based functional genomics screen

Authors: See, Stephanie Kum-Yin

DOI: https://escholarship.org/uc/item/627856jm

Thesis

Elucidating the role of autophagy in the clearance of phosphorylated tau protein in human neurons

Lotfy, Peter · 2016

Full title: Elucidating the role of autophagy in the clearance of phosphorylated tau protein in human neurons

Authors: Lotfy, Peter

DOI: https://escholarship.org/uc/item/854345k3

Thesis

Elucidating the Relationship Between NPC1 Mutations and Autophagy Dysregulation Using CRISPR-engineered Human Neurons

Wu, Emma · 2019

Full title: Elucidating the Relationship Between NPC1 Mutations and Autophagy Dysregulation Using CRISPR-engineered Human Neurons

Authors: Wu, Emma

DOI: https://escholarship.org/uc/item/7ct9h80c

Thesis

The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer disease

Zhi Tang (18687184) · 2014

Full title: The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer disease

Authors: Zhi Tang (18687184)

DOI: oai:figshare.com:article/26906134

Thesis

Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

Rasmus Berglund (18656620); Andre Ortlieb Guerreiro-Cacais (19851711); Milena Z Adzemovic (15444038) et al. · 2020

Full title: Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

DOI: oai:figshare.com:article/27233955

Thesis

Insulin and autophagy in neurodegeneration

Kawamoto, Elisa Mitiko · 2019

Full title: Insulin and autophagy in neurodegeneration

Authors: Kawamoto, Elisa Mitiko

DOI: https://doi.org/10.3389/fnins.2019.00491

Thesis

Autophagy modulation for organelle-targeting therapy

Martins, Waleska Kerllen · 2016

Full title: Autophagy modulation for organelle-targeting therapy

Authors: Martins, Waleska Kerllen

DOI: https://doi.org/10.5772/63976

Thesis

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions?: a systematic review

Tabnjh, Abedelmalek Kalefh · 2025

Full title: Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions?: a systematic review

Authors: Tabnjh, Abedelmalek Kalefh

DOI: http://dx.doi.org/10.3389/fncel.2025.1624500

Thesis

Effects of physical exercise on autophagy and apoptosis in aged brain: human and animal studies

Kawamoto, Elisa Mitiko · 2020

Full title: Effects of physical exercise on autophagy and apoptosis in aged brain: human and animal studies

Authors: Kawamoto, Elisa Mitiko

DOI: https://doi.org/10.3389/fnut.2020.00094

Thesis

MOLECULAR MECHANISMS AND THERAPEUTIC APPROACHES IN MN DISEASES

MERONI, MARCO · 2019

Full title: MOLECULAR MECHANISMS AND THERAPEUTIC APPROACHES IN MN DISEASES

Authors: MERONI, MARCO

DOI: http://hdl.handle.net/2434/608781

Thesis

AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES

CASIRAGHI, VALERIA · 2024

Full title: AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES

Authors: CASIRAGHI, VALERIA

DOI: https://hdl.handle.net/2434/1047008

Thesis

IMPACT OF LRRK2 KINASE ACTIVITY AT THE PRE-SYNAPTIC SITE: EARLY AND LATE EFFECTS ON PARKINSON'S DISEASE

M.D. Cirnaru · 2016

Full title: IMPACT OF LRRK2 KINASE ACTIVITY AT THE PRE-SYNAPTIC SITE: EARLY AND LATE EFFECTS ON PARKINSON'S DISEASE

Authors: M.D. Cirnaru

DOI: http://hdl.handle.net/2434/353078

Thesis

ASSESSING THE PATHOGENESIS OF MULTIPLE SYSTEM ATROPHY THROUGH CELLULAR MODELS

G. MONZIO COMPAGNONI · 2018

Full title: ASSESSING THE PATHOGENESIS OF MULTIPLE SYSTEM ATROPHY THROUGH CELLULAR MODELS

Authors: G. MONZIO COMPAGNONI

DOI: http://hdl.handle.net/2434/540359

Thesis

VALOSIN CONTAINING PROTEIN IN AMYOTROPHIC LATERAL SCLEROSIS: NEW INSIGHT IN PATHOLOGICAL MECHANISMS

FERRARI, VERONICA · 2020

Full title: VALOSIN CONTAINING PROTEIN IN AMYOTROPHIC LATERAL SCLEROSIS: NEW INSIGHT IN PATHOLOGICAL MECHANISMS

Authors: FERRARI, VERONICA

DOI: http://hdl.handle.net/2434/752322

Thesis

Discovery of Small-Molecule Autophagy Modulators in Mammalian Systems

Kuo, Szu-Yu · 2017

Full title: Discovery of Small-Molecule Autophagy Modulators in Mammalian Systems

Authors: Kuo, Szu-Yu

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33840641

Thesis

Investigation into the effects and mechanisms of rapamycin treatment in two mouse models of Complex I-deficient neurological pathology

Yanos, Melana · 2014

Full title: Investigation into the effects and mechanisms of rapamycin treatment in two mouse models of Complex I-deficient neurological pathology

Authors: Yanos, Melana

DOI: http://hdl.handle.net/1773/26136

Thesis

TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons

Hao, Jin · 2022

Full title: TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons

Authors: Hao, Jin

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371944

Thesis

Alpha-Synuclein Oligomers : Cellular Mechanisms and Aspects of Antibody Treatment

Gustafsson, Gabriel · 2017

Full title: Alpha-Synuclein Oligomers : Cellular Mechanisms and Aspects of Antibody Treatment

Authors: Gustafsson, Gabriel

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-326320

Thesis

The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

Rostami, Jinar · 2020

Full title: The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

Authors: Rostami, Jinar

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-425971

Thesis

mTOR at the nexus of nutrition, growth, ageing and disease

Liu, Grace Y; Sabatini, David M · 2021

Full title: mTOR at the nexus of nutrition, growth, ageing and disease

Authors: Liu, Grace Y; Sabatini, David M

DOI: https://hdl.handle.net/1721.1/136262

Thesis

The role of SQSTM1/P62 in axonal development and degeneration in an ALS-FTLD context

Young, Matthew J. · 2020

Full title: The role of SQSTM1/P62 in axonal development and degeneration in an ALS-FTLD context

Authors: Young, Matthew J.

DOI: https://eprints.nottingham.ac.uk/61004/1/M%20J%20Young%20stxmjy%20Thesis%20CORRECTED%20June%202020.pdf

Thesis

Blood-brain barrier functions and their impact on pharmacotherapy and pathogenesis of CNS disorders: novel in vitro and translational in vivo studies in animal models

Gericke, Birthe · 2024

Full title: Blood-brain barrier functions and their impact on pharmacotherapy and pathogenesis of CNS disorders: novel in vitro and translational in vivo studies in animal models

Authors: Gericke, Birthe

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-h-3145

Thesis

Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)

Foggin, Sophie · 2022

Full title: Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)

Authors: Foggin, Sophie

DOI: https://eprints.nottingham.ac.uk/71220/1/Sophie_Foggin_Thesis_2022_Corrections.pdf

Thesis

Does the activity of the proteasome decline during human ageing and in the brains of Parkinson’s disease patients?

Wayne, Declan · 2018

Full title: Does the activity of the proteasome decline during human ageing and in the brains of Parkinson’s disease patients?

Authors: Wayne, Declan

DOI: https://eprints.nottingham.ac.uk/55407/1/Thesis%20UPS%20in%20Parkinsons%20and%20Ageing%20Declan%20Wayne%20Finalised.pdf

Thesis

Exploring Lysosomal pH as a Therapeutic Strategy for Neurodegeneration

Chin, Marcus Yu-Yeung · 2021

Full title: Exploring Lysosomal pH as a Therapeutic Strategy for Neurodegeneration

Authors: Chin, Marcus Yu-Yeung

DOI: https://escholarship.org/uc/item/3xs387n6

Thesis

Synthesis of Alpha-Synuclein Proteolytic Targeting Chimeras and Selective Tau Tubulin Kinase I Inhibitors

Buczynski, Stanley · 2022

Full title: Synthesis of Alpha-Synuclein Proteolytic Targeting Chimeras and Selective Tau Tubulin Kinase I Inhibitors

Authors: Buczynski, Stanley

DOI: https://escholarship.org/uc/item/8cg624p0

Thesis

Regulation of mitochondrial autophagy by huntingtin

Margulis, Julia · 2016

Full title: Regulation of mitochondrial autophagy by huntingtin

Authors: Margulis, Julia

DOI: https://escholarship.org/uc/item/8kn713ss

Thesis

Mitochondrial degradation and chronic hyperactivity in Parkinson’s disease

Doric, Zak · 2022

Full title: Mitochondrial degradation and chronic hyperactivity in Parkinson’s disease

Authors: Doric, Zak

DOI: https://escholarship.org/uc/item/5qj1z426

Thesis

Targeting mitochondria as a potential therapeutic strategy in neurodegenerative disease

Hu, Di · 2019

Full title: Targeting mitochondria as a potential therapeutic strategy in neurodegenerative disease

Authors: Hu, Di

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1559999737544078

Thesis

Investigations into the cellular function of C9orf72

Webster, Christopher · 2016

Full title: Investigations into the cellular function of C9orf72

Authors: Webster, Christopher

DOI: https://etheses.whiterose.ac.uk/id/eprint/14385/1/160720_Thesis_Corrected.pdf

Thesis

Exploration of the role of TBK1 in autophagy and Amyotrophic Lateral Sclerosis

Davies, Maria · 2019

Full title: Exploration of the role of TBK1 in autophagy and Amyotrophic Lateral Sclerosis

Authors: Davies, Maria

DOI: https://etheses.whiterose.ac.uk/id/eprint/25167/1/Maria%20Davies%20Thesis%20October%202019.pdf

Thesis

Mechanisms of motor and non-motor complications in experimental parkinsonism

Carina Plewnia (18648865) · 2023

Full title: Mechanisms of motor and non-motor complications in experimental parkinsonism

Authors: Carina Plewnia (18648865)

DOI: oai:figshare.com:article/26915920

Thesis

Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease

Richeng Jiang (18661627) · 2022

Full title: Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease

Authors: Richeng Jiang (18661627)

DOI: oai:figshare.com:article/26925319

Thesis

Drug discovery targeting non-amyloid pathways in Alzheimer’s disease

Märta Dahlström (18681613) · 2020

Full title: Drug discovery targeting non-amyloid pathways in Alzheimer’s disease

Authors: Märta Dahlström (18681613)

DOI: oai:figshare.com:article/26921716

Thesis

REGULATION OF PROTEIN AGGREGATION BY ARFAPTIN2 IN AMYOTROPHIC LATERAL SCLEROSIS

Mohammedeid, Aida · 2015

Full title: REGULATION OF PROTEIN AGGREGATION BY ARFAPTIN2 IN AMYOTROPHIC LATERAL SCLEROSIS

Authors: Mohammedeid, Aida

DOI: https://etheses.whiterose.ac.uk/id/eprint/9377/1/Aida%20Mohammedeid%20final%20thesis.pdf

Thesis

The role of autophagy in Aβ and tau metabolism in Alzheimer’s disease

Johanna Mayer (18664930) · 2024

Full title: The role of autophagy in Aβ and tau metabolism in Alzheimer’s disease

Authors: Johanna Mayer (18664930)

DOI: oai:figshare.com:article/26921809

Thesis

Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Romani, Mario · 2021

Full title: Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Authors: Romani, Mario

DOI: https://infoscience.epfl.ch/handle/20.500.14299/175117

Thesis

Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

Mosser, Sébastien · 2016

Full title: Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

Authors: Mosser, Sébastien

DOI: https://infoscience.epfl.ch/handle/20.500.14299/123330

Thesis

Development of novel therapeutic approaches for treatment of Alzheimer's disease

Choo, Xin Yi · 2018

Full title: Development of novel therapeutic approaches for treatment of Alzheimer's disease

Authors: Choo, Xin Yi

DOI: http://hdl.handle.net/11343/216470

Thesis

Molecular and cellular insights into mitochondrial contributions to neuronal autophagy: links to energetics and mitophagy

SHIN, YEA SEUL · 2016

Full title: Molecular and cellular insights into mitochondrial contributions to neuronal autophagy: links to energetics and mitophagy

Authors: SHIN, YEA SEUL

DOI: http://hdl.handle.net/11343/103644

Thesis

Trehalose: a sweet solution for neurodegeneration?

Portbury, Stuart · 2017

Full title: Trehalose: a sweet solution for neurodegeneration?

Authors: Portbury, Stuart

DOI: http://hdl.handle.net/11343/194877

Thesis

Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration?

Liddell, JR · 2018

Full title: Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration?

Authors: Liddell, JR

DOI: https://hdl.handle.net/11343/198168

Thesis

Development and application of advanced bioimaging techniques to investigate stress pathways and drug action in neurodegeneration

James, Janine Louise · 2019

Full title: Development and application of advanced bioimaging techniques to investigate stress pathways and drug action in neurodegeneration

Authors: James, Janine Louise

DOI: http://hdl.handle.net/11343/228831

Thesis

Could Alzheimer’s Disease Originate in the Periphery and If So How So?

Morris, G; Berk, M; Maes, M et al. · 2020

Full title: Could Alzheimer’s Disease Originate in the Periphery and If So How So?

Authors: Morris, G; Berk, M; Maes, M; Puri, BK

DOI: https://hdl.handle.net/11343/254971

Thesis

Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Tuo, QZ; Zhang, ST; Lei, P · 2022

Full title: Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Authors: Tuo, QZ; Zhang, ST; Lei, P

DOI: https://hdl.handle.net/11343/298538

Thesis

Autophagy-inducing peptides as a therapy for Amyotrophic lateral sclerosis

Amin, Azin · 2022

Full title: Autophagy-inducing peptides as a therapy for Amyotrophic lateral sclerosis

Authors: Amin, Azin

DOI: https://hdl.handle.net/11343/311850

Thesis

Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Jiang, Q; Liu, J; Huang, S et al. · 2025

Full title: Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Authors: Jiang, Q; Liu, J; Huang, S; Wang, XY; Chen, X; Liu, GH; Ye, K; Song, W; Masters, CL; Wang, J; Wang, YJ

DOI: https://hdl.handle.net/11343/360219

Thesis

Using Caenorhabditis elegans to fight human neurodegenerative diseases

Chen, Xi; Kraemer, Brian; Barclay, Jeff et al. · 2013

Full title: Using Caenorhabditis elegans to fight human neurodegenerative diseases

Authors: Chen, Xi; Kraemer, Brian; Barclay, Jeff; Burgoyne, Robert; Morgan, Alan

DOI: https://livrepository.liverpool.ac.uk/2005121/5/ChenXi_Sep2014_2005121.pdf

Thesis

Modeling and Mechanistic Investigation of α-synuclein aggregation

Svanbergsson, Alexander · 2021

Full title: Modeling and Mechanistic Investigation of α-synuclein aggregation

Authors: Svanbergsson, Alexander

DOI: https://lup.lub.lu.se/record/cfaf28f7-c763-4223-9483-75daaeec1ad9

Thesis

Pharmacological and genetic manipulation of autophagy and its impact on diverse prion infection scenarios

Aguib, Yasmine · 2012

Full title: Pharmacological and genetic manipulation of autophagy and its impact on diverse prion infection scenarios

Authors: Aguib, Yasmine

DOI: https://mediatum.ub.tum.de/1108173

Thesis

Role of Neuroinflammation in Parkinson's Disease and Related Disorders

Brandi, Edoardo · 2022

Full title: Role of Neuroinflammation in Parkinson's Disease and Related Disorders

Authors: Brandi, Edoardo

DOI: https://lup.lub.lu.se/record/bfd651d7-e127-4afc-86fe-bfc8c76baa72

Thesis

Correlative cryo-electron tomography studies of artificial beta-protein aggregates in mammalian cells

Schäfer, Tillman · 2018

Full title: Correlative cryo-electron tomography studies of artificial beta-protein aggregates in mammalian cells

Authors: Schäfer, Tillman

DOI: https://mediatum.ub.tum.de/1452151

Thesis

Prions and autophagy: Effect of lithium on prion infection and role of basal autophagy in primary prion infection

Heiseke, Andreas · 2010

Full title: Prions and autophagy: Effect of lithium on prion infection and role of basal autophagy in primary prion infection

Authors: Heiseke, Andreas

DOI: https://mediatum.ub.tum.de/818228

Thesis

Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor et al. · 2018

Full title: Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Authors: Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor; Tsunoda, Susan, committee member

DOI: https://hdl.handle.net/10217/191325

Thesis

Glial inflammation as a key regulator and therapeutic target for prion disease

Hay, Arielle, author; Zabel, Mark, advisor; Moreno, Julie, advisor et al. · 2023

Full title: Glial inflammation as a key regulator and therapeutic target for prion disease

Authors: Hay, Arielle, author; Zabel, Mark, advisor; Moreno, Julie, advisor; Tjalkens, Ronald, committee member; Chanda, Soham, committee member; Santangelo, Kelly, committee member

DOI: https://hdl.handle.net/10217/236942

Thesis

Defective Autophagy in Neurodegeneration: Novel Roles for Huntingtin and Optineurin in Regulating Autophagosome Dynamics

Wong, Chyi Haw Yvette · 2023

Full title: Defective Autophagy in Neurodegeneration: Novel Roles for Huntingtin and Optineurin in Regulating Autophagosome Dynamics

Authors: Wong, Chyi Haw Yvette

DOI: https://repository.upenn.edu/handle/20.500.14332/27949

Thesis

Structural Remodeling Of Alpha-Synuclein By Small Molecules: A Novel Path To Neuroprotective Therapeutics

Daniels, Malcolm James · 2023

Full title: Structural Remodeling Of Alpha-Synuclein By Small Molecules: A Novel Path To Neuroprotective Therapeutics

Authors: Daniels, Malcolm James

DOI: https://repository.upenn.edu/handle/20.500.14332/29705

Thesis

Engineering Protein Disaggregases To Counter Alpha-Synuclein And Amyloid-Beta Neurotoxicity

Mack, Korrie Lynne · 2023

Full title: Engineering Protein Disaggregases To Counter Alpha-Synuclein And Amyloid-Beta Neurotoxicity

Authors: Mack, Korrie Lynne

DOI: https://repository.upenn.edu/handle/20.500.14332/30511

Thesis

Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila

Saikumar, Janani · 2023

Full title: Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila

Authors: Saikumar, Janani

DOI: https://repository.upenn.edu/handle/20.500.14332/31231

Thesis

Structure And Function Of A Disease Associated Tau Disaggregase

Darwich, Nabil · 2023

Full title: Structure And Function Of A Disease Associated Tau Disaggregase

Authors: Darwich, Nabil

DOI: https://repository.upenn.edu/handle/20.500.14332/30669

Thesis

Increased Expression of Frontotemporal Dementia Risk Factor Tmem106b Alters Lysosomal and Autophagosomal Pathways

Busch, Johanna Irene · 2023

Full title: Increased Expression of Frontotemporal Dementia Risk Factor Tmem106b Alters Lysosomal and Autophagosomal Pathways

Authors: Busch, Johanna Irene

DOI: https://repository.upenn.edu/handle/20.500.14332/28462

Thesis

A Role for Lysosomal PH Dysfunction in Alzheimer’s Disease and Strategies for its Restoration

Coffey, Erin · 2023

Full title: A Role for Lysosomal PH Dysfunction in Alzheimer’s Disease and Strategies for its Restoration

Authors: Coffey, Erin

DOI: https://repository.upenn.edu/handle/20.500.14332/28497

Thesis

Proteostasis Responses to Endogenous Alpha-Synuclein Aggregation in the Brain

Ugras, Scott Edward · 2023

Full title: Proteostasis Responses to Endogenous Alpha-Synuclein Aggregation in the Brain

Authors: Ugras, Scott Edward

DOI: https://repository.upenn.edu/handle/20.500.14332/28946

Thesis

MITOPHAGY INITIATION IS IMPAIRED BY NEURODEGENERATIVE-LINKED MUTATIONS AND INDUCES NF-ĸB INFLAMMATION

Harding, Olivia · 2023

Full title: MITOPHAGY INITIATION IS IMPAIRED BY NEURODEGENERATIVE-LINKED MUTATIONS AND INDUCES NF-ĸB INFLAMMATION

Authors: Harding, Olivia

DOI: https://repository.upenn.edu/handle/20.500.14332/58991

Thesis

The Interplay Between Lewy Body-Like Alpha-Synuclein Aggregates nd Protein Degradation Pathways in Cell-Based Model of Parkinson's Disease

Tanik, Selcuk Aski · 2023

Full title: The Interplay Between Lewy Body-Like Alpha-Synuclein Aggregates nd Protein Degradation Pathways in Cell-Based Model of Parkinson's Disease

Authors: Tanik, Selcuk Aski

DOI: https://repository.upenn.edu/handle/20.500.14332/32474

Thesis

Compartment-Specific Regulation Of Autophagy In Neurons

Kulkarni, Vineet Vinay · 2023

Full title: Compartment-Specific Regulation Of Autophagy In Neurons

Authors: Kulkarni, Vineet Vinay

DOI: https://repository.upenn.edu/handle/20.500.14332/31552

Thesis

Regional Lysosomal Malfunction Underlies the Selectivity of α-Synuclein Neurodegeneration

Malkus, Kristen A · 2023

Full title: Regional Lysosomal Malfunction Underlies the Selectivity of α-Synuclein Neurodegeneration

Authors: Malkus, Kristen A

DOI: https://repository.upenn.edu/handle/20.500.14332/32756

Thesis

Mechanisms regulating the clearance of damaged lysosomes

Gallagher, Elizabeth, Raye · 2025

Full title: Mechanisms regulating the clearance of damaged lysosomes

Authors: Gallagher, Elizabeth, Raye

DOI: https://repository.upenn.edu/handle/20.500.14332/60816

Thesis

Green Tea Catechins as a Prebiotic Intervention for Modulation of the Gut Microbiome, Metabolome, and Alpha-Synuclein in Parkinson’s Disease

Riegelman, Elizabeth C · 2025

Full title: Green Tea Catechins as a Prebiotic Intervention for Modulation of the Gut Microbiome, Metabolome, and Alpha-Synuclein in Parkinson’s Disease

Authors: Riegelman, Elizabeth C

DOI: https://openscholar.uga.edu/record/26630/files/ERiegelman_DissertationFINAL.pdf

Thesis

EGCG directly targets intracellular amyloid-β(1-42) aggregates and promotes their lysosomal degradation

Secker, Christopher · 2019

Full title: EGCG directly targets intracellular amyloid-β(1-42) aggregates and promotes their lysosomal degradation

Authors: Secker, Christopher

DOI: https://refubium.fu-berlin.de/handle/fub188/23977

Thesis

The role of autophagy in Alzheimer disease

Jäger, Philipp · 2011

Full title: The role of autophagy in Alzheimer disease

Authors: Jäger, Philipp

DOI: https://refubium.fu-berlin.de/handle/fub188/4120

Thesis

Spermidine-induced autophagy and its effect on Alzheimer´s disease pathogenesis in mice

Freitag, Kiara · 2023

Full title: Spermidine-induced autophagy and its effect on Alzheimer´s disease pathogenesis in mice

Authors: Freitag, Kiara

DOI: https://refubium.fu-berlin.de/handle/fub188/40859

Thesis

Analysis of the interplay between protein quality control pathways in aging and neurodegenerative diseases

Rodrigues Feleciano, Diogo · 2019

Full title: Analysis of the interplay between protein quality control pathways in aging and neurodegenerative diseases

Authors: Rodrigues Feleciano, Diogo

DOI: https://refubium.fu-berlin.de/handle/fub188/23722

Thesis

Complementary methodologies and diverse model systems provide translational insight into the aggregation properties of neurodegenerative diseases

Pigazzini, Maria Lucia · 2022

Full title: Complementary methodologies and diverse model systems provide translational insight into the aggregation properties of neurodegenerative diseases

Authors: Pigazzini, Maria Lucia

DOI: https://refubium.fu-berlin.de/handle/fub188/34073

Thesis

Perturbations of proteostasis networks in Alzheimer´s disease: Focus on the ubiquitin proteasome system

Schormann, Eileen Josephine · 2019

Full title: Perturbations of proteostasis networks in Alzheimer´s disease: Focus on the ubiquitin proteasome system

Authors: Schormann, Eileen Josephine

DOI: https://refubium.fu-berlin.de/handle/fub188/24086

Thesis

Autophagy in Microglia and Alzheimer's disease

Houtman, Judith · 2019

Full title: Autophagy in Microglia and Alzheimer's disease

Authors: Houtman, Judith

DOI: https://refubium.fu-berlin.de/handle/fub188/25471

Thesis

Modifying prion disease development by ablation of galectin-3 and by simvastatin-treatment

Mok, Simon Wing-Fai · 2012

Full title: Modifying prion disease development by ablation of galectin-3 and by simvastatin-treatment

Authors: Mok, Simon Wing-Fai

DOI: https://refubium.fu-berlin.de/handle/fub188/8203

Thesis

Autophagy and its role in synapse function

Hoffmann, Sheila Sook-Hi · 2019

Full title: Autophagy and its role in synapse function

Authors: Hoffmann, Sheila Sook-Hi

DOI: https://refubium.fu-berlin.de/handle/fub188/24487

Thesis

Mechanistic target of rapamycin is required for sensory axon regeneration and functional recovery

Chen, Weitao · 2018

Full title: Mechanistic target of rapamycin is required for sensory axon regeneration and functional recovery

Authors: Chen, Weitao

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-114526

Thesis

α-synuclein degradation dynamics and the evaluation of a new mouse model in Parkinson’s disease

Lam, Wai Yun · 2021

Full title: α-synuclein degradation dynamics and the evaluation of a new mouse model in Parkinson’s disease

Authors: Lam, Wai Yun

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-129891

Thesis

Functional characterization of Cdk5-mediated phosphorylation of endophilin B1 in macroautophagy in models of parkinson's disease

Wong, Siu Lun · 2011

Full title: Functional characterization of Cdk5-mediated phosphorylation of endophilin B1 in macroautophagy in models of parkinson's disease

Authors: Wong, Siu Lun

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-7348

Thesis

Improving Mitochondrial Function in the Aging and Diseased Brain

Ng, Jin · 2019

Full title: Improving Mitochondrial Function in the Aging and Diseased Brain

Authors: Ng, Jin

DOI: https://hdl.handle.net/2292/46858

Thesis

Mitochondria: An Emerging Therapeutic Target for Neurodegeneration

Dhar, Krishayant Shiri · 2025

Full title: Mitochondria: An Emerging Therapeutic Target for Neurodegeneration

Authors: Dhar, Krishayant Shiri

DOI: https://hdl.handle.net/2123/34175

Thesis

Identification of Novel Modulators for Neurodegenerative Disease States

Garrett, Taylor Ray · 2025

Full title: Identification of Novel Modulators for Neurodegenerative Disease States

Authors: Garrett, Taylor Ray

DOI: https://hdl.handle.net/2123/33832

Thesis

The role of autophagy in TLR2-mediated alpha-synuclein accumulation in neurons.

Chedid, Jessica · 2023

Full title: The role of autophagy in TLR2-mediated alpha-synuclein accumulation in neurons.

Authors: Chedid, Jessica

DOI: https://hdl.handle.net/2123/31817

Thesis

Identification de molécules neuroprotectrices, facteurs de transcription et voies de signalisation en jeu pour la maladie de Machado-Joseph par un modèle transgénique C. elegans

Fard Ghassemi, Yasmin · 2022

Full title: Identification de molécules neuroprotectrices, facteurs de transcription et voies de signalisation en jeu pour la maladie de Machado-Joseph par un modèle transgénique C. elegans

Authors: Fard Ghassemi, Yasmin

DOI: http://hdl.handle.net/1866/26869

Thesis

Autophagy-lysosomal pathway dysfunction in Parkinson’s disease

Murphy, Karen · 2013

Full title: Autophagy-lysosomal pathway dysfunction in Parkinson’s disease

Authors: Murphy, Karen

DOI: http://hdl.handle.net/1959.4/53379

Thesis

Investigating the potential role of the M1 muscarinic acetylcholine receptor in misfolded protein propagation

Alepuz Guillen, Jose Andres · 2024

Full title: Investigating the potential role of the M1 muscarinic acetylcholine receptor in misfolded protein propagation

Authors: Alepuz Guillen, Jose Andres

DOI: https://theses.gla.ac.uk/84698/1/2024AlepuzGuillenPhD.pdf

Thesis

Dysregulated miRNA Expression in Parkinson’s Disease Results in Impaired Endocytosis, Mitochondrial Dysfunction and Lysosome Dyshomeostasis

Duly, Alastair · 2018

Full title: Dysregulated miRNA Expression in Parkinson’s Disease Results in Impaired Endocytosis, Mitochondrial Dysfunction and Lysosome Dyshomeostasis

Authors: Duly, Alastair

DOI: http://hdl.handle.net/1959.4/61686

Thesis

Clinical aspects and in vitro modelling of GBA1 variant-associated Parkinson's disease

Stoker, Thomas Benjamin · 2020

Full title: Clinical aspects and in vitro modelling of GBA1 variant-associated Parkinson's disease

Authors: Stoker, Thomas Benjamin

DOI: https://www.repository.cam.ac.uk/handle/1810/301989

Thesis

Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.

Kreiser, Ryan P; Wright, Aidan K; Block, Natalie R et al. · 2020

Full title: Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.

Authors: Kreiser, Ryan P; Wright, Aidan K; Block, Natalie R; Hollows, Jared E; Nguyen, Lam T; LeForte, Kathleen; Mannini, Benedetta; Vendruscolo, Michele; Limbocker, Ryan

DOI: https://www.repository.cam.ac.uk/handle/1810/313119

Thesis

Autophagy in major human diseases.

Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K et al. · 2021

Full title: Autophagy in major human diseases.

DOI: https://www.repository.cam.ac.uk/handle/1810/325129

Thesis

Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease

Barker, Roger · 2022

Full title: Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease

Authors: Barker, Roger

DOI: https://www.repository.cam.ac.uk/handle/1810/332257

Thesis

The different autophagy degradation pathways and neurodegeneration.

Fleming, Angeleen; Bourdenx, Mathieu; Fujimaki, Motoki et al. · 2022

Full title: The different autophagy degradation pathways and neurodegeneration.

DOI: https://www.repository.cam.ac.uk/handle/1810/335336

Thesis

Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Wrobel, Lidia; Hill, Sandra M; Djajadikerta, Alvin et al. · 2022

Full title: Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

DOI: https://www.repository.cam.ac.uk/handle/1810/340198

Thesis

Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.

Son, Sung Min; Siddiqi, Farah H; Lopez, Ana et al. · 2025

Full title: Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.

Authors: Son, Sung Min; Siddiqi, Farah H; Lopez, Ana; Ansari, Rizwan; Tyrkalska, Sylwia D; Park, So Jung; Kunath, Tilo; Metzakopian, Emmanouil; Fleming, Angeleen; Rubinsztein, David C

DOI: https://www.repository.cam.ac.uk/handle/1810/381916

Thesis

RNA binding proteins in neurotoxic protein clearance

Ryan, Laura · 2024

Full title: RNA binding proteins in neurotoxic protein clearance

Authors: Ryan, Laura

DOI: https://www.repository.cam.ac.uk/handle/1810/370046

Thesis

Human Embryonic stem cell-derived A9 dopaminergic neurons as a model and therapy for Parkinson's disease

Skidmore, Sophie · 2023

Full title: Human Embryonic stem cell-derived A9 dopaminergic neurons as a model and therapy for Parkinson's disease

Authors: Skidmore, Sophie

DOI: https://www.repository.cam.ac.uk/handle/1810/353732

Thesis

Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion

Rubinsztein, David; Lopez, Ana; Siddiqi, Farah et al. · 2025

Full title: Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion

Authors: Rubinsztein, David; Lopez, Ana; Siddiqi, Farah; Keeling, Sophie; McEwan, William; Fleming, Angeleen

DOI: https://www.repository.cam.ac.uk/handle/1810/374034

Thesis

El papel del sistema autofágico lisosomal en las enfermedades con cuerpos de Lewy

Pérez Roca, Laia · 2021

Full title: El papel del sistema autofágico lisosomal en las enfermedades con cuerpos de Lewy

Authors: Pérez Roca, Laia

DOI: http://hdl.handle.net/10803/672055

Thesis

Investigation of the role and modulation of autophagy for neuroprotection and nerve regeneration using models of peripheral nerve injury

Leiva Rodríguez, Tatiana · 2019

Full title: Investigation of the role and modulation of autophagy for neuroprotection and nerve regeneration using models of peripheral nerve injury

Authors: Leiva Rodríguez, Tatiana

DOI: http://hdl.handle.net/10803/667461

Thesis

Transcription factor EB-mediated neurotrophic and neuroprotective effects: relevance to Parkinson’s disease

Torra i Talavera, Albert · 2019

Full title: Transcription factor EB-mediated neurotrophic and neuroprotective effects: relevance to Parkinson’s disease

Authors: Torra i Talavera, Albert

DOI: http://hdl.handle.net/10803/667794

Thesis

Therapeutic targeting of mitophagy in Parkinson's disease

Masaldan, S; Callegari, S; Dewson, G · 2022

Full title: Therapeutic targeting of mitophagy in Parkinson's disease

Authors: Masaldan, S; Callegari, S; Dewson, G

DOI: https://hdl.handle.net/11343/308650

Thesis

Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease

Portbury, SD; Hare, DJ; Sgambelloni, C et al. · 2020

Full title: Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease

Authors: Portbury, SD; Hare, DJ; Sgambelloni, C; Perronnes, K; Portbury, AJ; Finkelstein, DI; Adlard, PA

DOI: https://hdl.handle.net/11343/256837

Thesis

Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

Vessey, KA; Jobling, AI; Tran, MX et al. · 2022

Full title: Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

Authors: Vessey, KA; Jobling, AI; Tran, MX; Wang, AY; Greferath, U; Fletcher, EL

DOI: https://hdl.handle.net/11343/302830

Thesis

Amyotrophic lateral sclerosis and autophagy: Dysfunction and therapeutic targeting

Amin, A; Perera, ND; Beart, PM et al. · 2021

Full title: Amyotrophic lateral sclerosis and autophagy: Dysfunction and therapeutic targeting

Authors: Amin, A; Perera, ND; Beart, PM; Turner, BJ; Shabanpoor, F

DOI: https://hdl.handle.net/11343/272091

Thesis

The proteostasis network provides targets for neurodegeneration

Newton, TM; Duce, JA; Bayle, ED · 2021

Full title: The proteostasis network provides targets for neurodegeneration

Authors: Newton, TM; Duce, JA; Bayle, ED

DOI: https://hdl.handle.net/11343/285815

Thesis

Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

Wang, J; Bi, W; Zhao, W et al. · 2022

Full title: Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

Authors: Wang, J; Bi, W; Zhao, W; Varghese, M; Koch, RJ; Walker, RH; Chandraratna, RA; Sanders, ME; Janesick, A; Blumberg, B; Ward, L; Ho, L; Pasinetti, GM

DOI: https://hdl.handle.net/11343/316567

Thesis

Therapeutics for dementia and Alzheimer's disease: New directions for precision medicine

Duce, JA; Zhu, X; Jacobson, LH et al. · 2021

Full title: Therapeutics for dementia and Alzheimer's disease: New directions for precision medicine

Authors: Duce, JA; Zhu, X; Jacobson, LH; Beart, PM

DOI: https://hdl.handle.net/11343/286279

Thesis

Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson’s Disease Model

Azam, S; Haque, ME; Cho, DY et al. · 2022

Full title: Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson’s Disease Model

Authors: Azam, S; Haque, ME; Cho, DY; Kim, JS; Jakaria, M; Kim, IS; Choi, DK

DOI: https://hdl.handle.net/11343/309009

Thesis

Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Matysek, A; Kimmantudawage, SP; Feng, L et al. · 2022

Full title: Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Authors: Matysek, A; Kimmantudawage, SP; Feng, L; Maier, AB

DOI: https://hdl.handle.net/11343/317284

Thesis

Peroxisome proliferator activator receptor gamma coactivator-1α overexpression in amyotrophic lateral sclerosis: A tale of two transgenics

Varghese, M; Zhao, W; Trageser, KJ et al. · 2022

Full title: Peroxisome proliferator activator receptor gamma coactivator-1α overexpression in amyotrophic lateral sclerosis: A tale of two transgenics

Authors: Varghese, M; Zhao, W; Trageser, KJ; Pasinetti, GM

DOI: https://hdl.handle.net/11343/316565

Thesis

Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

Choo, XY; McInnes, LE; Grubman, A et al. · 2022

Full title: Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

DOI: https://hdl.handle.net/11343/322271

Thesis

Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy

De Silva, S; Turner, BJ; Perera, ND · 2022

Full title: Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy

Authors: De Silva, S; Turner, BJ; Perera, ND

DOI: https://hdl.handle.net/11343/316752

Thesis

Messenger RNA-encoded antibody approach for targeting extracellular and intracellular tau

Wongsodirdjo, P; Caruso, AC; Yong, AK et al. · 2024

Full title: Messenger RNA-encoded antibody approach for targeting extracellular and intracellular tau

Authors: Wongsodirdjo, P; Caruso, AC; Yong, AK; Lester, MA; Vella, LJ; Hung, YH; Nisbet, RM

DOI: https://hdl.handle.net/11343/344638

Thesis

Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans

Wu, Y; Chen, Y; Yu, X et al. · 2024

Full title: Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans

Authors: Wu, Y; Chen, Y; Yu, X; Zhang, M; Li, Z

DOI: https://hdl.handle.net/11343/353037

Thesis

In vivo Assessment of Lysosomal Stress in the Drosophila Brain Using Confocal Fluorescence Microscopy

Martelli, F · 2024

Full title: In vivo Assessment of Lysosomal Stress in the Drosophila Brain Using Confocal Fluorescence Microscopy

Authors: Martelli, F

DOI: https://hdl.handle.net/11343/354186

Thesis

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

· 2025

Full title: Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

DOI: https://hdl.handle.net/11343/362674

Thesis

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis

Lum, JS; Brown, ML; Farrawell, NE et al. · 2025

Full title: A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis

Authors: Lum, JS; Brown, ML; Farrawell, NE; Bartlett, R; Chisholm, CG; Gorman, J; Dosseto, A; Dux, F; McInnes, LE; Ecroyd, H; McAlary, L; Crouch, PJ; Donnelly, PS; Yerbury, JJ

DOI: https://hdl.handle.net/11343/360500

Thesis

CLN5 deficiency results in alterations in the activation of autophagy

Budden, Theodore · 2015

Full title: CLN5 deficiency results in alterations in the activation of autophagy

Authors: Budden, Theodore

DOI: http://hdl.handle.net/2097/20473

Thesis

Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

Sedlackova, Lucia; Otten, Elsje; Scialo, Filippo et al. · 2020

Full title: Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

DOI: oai:livrepository.liverpool.ac.uk:3139242

Thesis

Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Chen, Xi; McCuef, Hannah V; Wong, Shi Quan et al. · 2015

Full title: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Authors: Chen, Xi; McCuef, Hannah V; Wong, Shi Quan; Kashyap, Sudhanva S; Kraemer, Brian C; Barclay, Jeff W; Burgoyne, Robert D; Morgan, Alan

DOI: https://livrepository.liverpool.ac.uk/3000235/1/Ethosuximide%20ameliorates%20neurodegenerative%20disease%20phenotypes%20by%20modulating%20DAF-16/FOXO%20target%20gene%20expression.pdf

Thesis

Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

Källstig, Emma · 2017

Full title: Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

Authors: Källstig, Emma

DOI: http://lup.lub.lu.se/student-papers/record/8925257

Thesis

Extracellular Vesicles, Cell-Penetrating Peptides and miRNAs as Future Novel Therapeutic Interventions for Parkinson's and Alzheimer's Disease

Keighron, Cameron Noah; Avazzadeh, Sahar; Goljanek-Whysall, Katarzyna et al. · 2023

Full title: Extracellular Vesicles, Cell-Penetrating Peptides and miRNAs as Future Novel Therapeutic Interventions for Parkinson's and Alzheimer's Disease

Authors: Keighron, Cameron Noah; Avazzadeh, Sahar; Goljanek-Whysall, Katarzyna; McDonagh, Brian; Howard, Linda; Ritter, Thomas; Quinlan, Leo RR

Thesis

Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Hoffmann, Anna-Carin; Minakaki, Georgia; Menges, Stefanie et al. · 2019

Full title: Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Authors: Hoffmann, Anna-Carin;Minakaki, Georgia;Menges, Stefanie;Salvi, Rachele;Savitskiy, Sergey;Kazman, Aida;Vicente Miranda, Hugo;Mielenz, Dirk;Klucken, Jochen;Winkler, Jürgen;Xiang, Wei

DOI: https://mediatum.ub.tum.de/1544300

Thesis

Using cannabidiol and trazodone to treat protein misfolding neurodegenerative disease in C. elegans

Gilberto, Vincenzo S., author; Moreno, Julie A., advisor; Legare, Marie, committee member et al. · 2022

Full title: Using cannabidiol and trazodone to treat protein misfolding neurodegenerative disease in C. elegans

DOI: https://hdl.handle.net/10217/235653

Thesis

The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Campagno, Keith E.; Mitchell, Claire H. · 2023

Full title: The P2X7 Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Authors: Campagno, Keith E.; Mitchell, Claire H.

DOI: https://repository.upenn.edu/handle/20.500.14332/58680

Thesis

Autophagy in the Eye: Implications for Ocular Cell Health

Frost, Laura S.; Mitchell, Claire H.; Boesze-Battaglia, Kathleen · 2023

Full title: Autophagy in the Eye: Implications for Ocular Cell Health

Authors: Frost, Laura S.; Mitchell, Claire H.; Boesze-Battaglia, Kathleen

DOI: https://repository.upenn.edu/handle/20.500.14332/8962

Thesis

Neue Wirkstoffe für die Therapie von Morbus Alzheimer, Morbus Parkinson und Chorea Huntington

Strohmeier, Barbara · 2017

Full title: Neue Wirkstoffe für die Therapie von Morbus Alzheimer, Morbus Parkinson und Chorea Huntington

Authors: Strohmeier, Barbara

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-110222

Thesis

The role of PARK9 in zinc homeostasis, alpha-synuclein toxicity and Parkinson’s disease

Chan, Brian · 2011

Full title: The role of PARK9 in zinc homeostasis, alpha-synuclein toxicity and Parkinson’s disease

Authors: Chan, Brian

DOI: http://hdl.handle.net/1959.4/51536

Thesis

Investigating the ATP13A2 (PARK9) and a- Synuclein inter-relationship in Parkinson’s Disease

Cottle, Louise Ellen · 2018

Full title: Investigating the ATP13A2 (PARK9) and a- Synuclein inter-relationship in Parkinson’s Disease

Authors: Cottle, Louise Ellen

DOI: http://hdl.handle.net/1959.4/60575

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