Pharma Investment In Primary Human Cell In Vitro M

jade

1. Documents

1465

123 papers 702 patents 640 theses

Full text available

Paper Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Papadopoulos, Nicholas; Martin, Joel; Ruan, Qin et al. · 2012 · Angiogenesis · DOI

Full title: Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Authors: Papadopoulos, Nicholas; Martin, Joel; Ruan, Qin; Rafique, Ashique; Rosconi, Michael; Shi, Ergang; Pyles, Erica; Yancopoulos, George D.; Stahl, Neil; Wiegand, Stanley J.

Year: 2012

Venue: Angiogenesis

DOI: https://doi.org/10.1007/s10456-011-9249-6

Paper Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Abdelfatah, Sara; Naß, Janine; Knorz, Caroline et al. · 2021 · Cell Biology and Toxicology · DOI

Full title: Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Authors: Abdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan‐Heiner; Efferth, Thomas

Year: 2021

Venue: Cell Biology and Toxicology

DOI: https://doi.org/10.1007/s10565-021-09599-9

Paper Cellulose-based hydrogel materials: chemistry, properties and their prospective applications

Kabir, S M Fijul; Sikdar, Partha; Haque, Bazle Z. et al. · 2018 · Progress in Biomaterials · DOI

Full title: Cellulose-based hydrogel materials: chemistry, properties and their prospective applications

Authors: Kabir, S M Fijul; Sikdar, Partha; Haque, Bazle Z.; Bhuiyan, M. A. Rahman; Ali, Ayub; Islam, Md. Nurul

Year: 2018

Venue: Progress in Biomaterials

DOI: https://doi.org/10.1007/s40204-018-0095-0

Paper Mesenchymal stem cells and immunomodulation: current status and future prospects

Gao, Fei; Chiu, Sheng‐Hao; Motan, Daniyal et al. · 2016 · Cell Death and Disease · DOI

Full title: Mesenchymal stem cells and immunomodulation: current status and future prospects

Authors: Gao, Fei; Chiu, Sheng‐Hao; Motan, Daniyal; Zhang, Z.; Chen, L.; Ji, H-L; Tse, Hung‐Fat; Fu, Q-L; Lian, Qizhou

Year: 2016

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2015.327

Paper Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Li, Hongyi; Yang, Yang; Hong, Weiqi et al. · 2020 · Signal Transduction and Targeted Therapy · DOI

Full title: Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Authors: Li, Hongyi; Yang, Yang; Hong, Weiqi; Huang, Mengyuan; Wu, Min; Zhao, Xia

Year: 2020

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-019-0089-y

Paper Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Cao, Huấn; Duan, Lixia; Zhang, Yan et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Authors: Cao, Huấn; Duan, Lixia; Zhang, Yan; Cao, Jun; Zhang, Kun

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00830-x

Paper A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Slyper, Michal; Porter, Caroline; Ashenberg, Orr et al. · 2020 · Nature Medicine · DOI

Full title: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Authors: Slyper, Michal; Porter, Caroline; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher S.; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sébastien; Jané‐Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlström, Åsa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby‐Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Nguyễn, Lan; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suvà, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt–Rosen, Orit; Regev, Aviv

Year: 2020

Venue: Nature Medicine

DOI: https://doi.org/10.1038/s41591-020-0844-1

Paper Comparative cellular analysis of motor cortex in human, marmoset and mouse

Bakken, Trygve E.; Jorstad, Nikolas L.; Hu, Qiwen et al. · 2021 · Nature · DOI

Full title: Comparative cellular analysis of motor cortex in human, marmoset and mouse

Authors: Bakken, Trygve E.; Jorstad, Nikolas L.; Hu, Qiwen; Lake, Blue B.; Tian, Wei; Kalmbach, Brian; Crow, Megan; Hodge, Rebecca D.; Krienen, Fenna M.; Sorensen, Staci A.; Eggermont, Jeroen; Yao, Zizhen; Aevermann, Brian D.; Aldridge, Andrew; Bartlett, Anna; Bertagnolli, Darren; Casper, Tamara; Castanon, Rosa; Crichton, Kirsten; Daigle, Tanya L.; Dalley, Rachel; Dee, Nick; Dembrow, Nikolai; Diep, Dinh; Ding, Song‐Lin; Dong, Weixiu; Fang, Rongxin; Fischer, Stephan; Goldman, Melissa; Goldy, Jeff; Graybuck, Lucas T.; Herb, Brian R.; Hou, Xiaomeng; Kancherla, Jayaram; Kroll, Matthew; Lathia, Kanan; Lew, Baldur van; Li, Yang Eric; Liu, Christine S.; Liu, Hanqing; Lucero, Jacinta; Mahurkar, Anup; McMillen, Delissa; Miller, Jeremy A.; Moussa, Marmar R.; Nery, Joseph R.; Nicovich, Philip R.; Niu, Sheng-Yong; Orvis, Joshua; Osteen, Julia; Owen, Scott F.; Palmer, Carter R.; Pham, Thanh; Plongthongkum, Nongluk; Poirion, Olivier; Reed, Nora; Rimorin, Christine; Rivkin, Angeline; Romanow, William J.; Sedeño-Cortés, Adriana E.; Siletti, Kimberly; Somasundaram, Saroja; Šulc, Josef; Tieu, Michael; Torkelson, Amy; Tung, Herman; Wang, Xinxin; Xie, Fangming; Yanny, Anna Marie; Zhang, Yun; Ament, Seth A.; Behrens, M. Margarita; Bravo, Héctor Corrada; Chun, Jerold; Dobin, Alexander; Gillis, Jesse; Hertzano, Ronna; Hof, Patrick R.; Höllt, Thomas; Horwitz, Gregory D.; Keene, C. Dirk; Kharchenko, Peter V.; Ko, Andrew L.; Lelieveldt, Boudewijn P. F.; Luo, Chongyuan; Mukamel, Eran A.; Pinto‐Duarte, António; Preißl, Sebastian; Regev, Aviv; Ren, Bing; Scheuermann, Richard H.; Smith, Kimberly A.; Spain, William J.; White, Owen; Koch, Christof; Hawrylycz, Michael; Tasic, Bosiljka; Macosko, Evan Z.; McCarroll, Steven A.; Ting, Jonathan T.

Year: 2021

Venue: Nature

DOI: https://doi.org/10.1038/s41586-021-03465-8

Paper Embryonic stem cell differentiation: emergence of a new era in biology and medicine

Keller, Gordon · 2005 · Genes & Development · DOI

Full title: Embryonic stem cell differentiation: emergence of a new era in biology and medicine

Authors: Keller, Gordon

Year: 2005

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.1303605

Paper Intestinal permeability – a new target for disease prevention and therapy

Bischoff, Stephan C.; Barbara, Giovanni; Buurman, Wim A. et al. · 2014 · BMC Gastroenterology · DOI

Full title: Intestinal permeability – a new target for disease prevention and therapy

Authors: Bischoff, Stephan C.; Barbara, Giovanni; Buurman, Wim A.; Ockhuizen, Theo; Schulzke, Jörg–Dieter; Sérino, Matteo; Tilg, Herbert; Watson, Alastair J.M.; Wells, Jerry M.

Year: 2014

Venue: BMC Gastroenterology

DOI: https://doi.org/10.1186/s12876-014-0189-7

Paper CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

Lopes‐Pacheco, Miquéias · 2020 · Frontiers in Pharmacology · DOI

Full title: CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

Authors: Lopes‐Pacheco, Miquéias

Year: 2020

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2019.01662

Paper Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases

Dodina, Maria; Gurtsieva, Dzerassa; Karabelsky, Alexander et al. · 2024 · Frontiers in Cell and Developmental Biology · DOI

Full title: Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases

Authors: Dodina, Maria; Gurtsieva, Dzerassa; Karabelsky, Alexander; Minskaia, Ekaterina

Year: 2024

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2024.1455140

Paper A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds

Reddy, M. Sai Bhargava; Ponnamma, Deepalekshmi; Choudhary, Rajan et al. · 2021 · Polymers · DOI

Full title: A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds

Authors: Reddy, M. Sai Bhargava; Ponnamma, Deepalekshmi; Choudhary, Rajan; Sadasivuni, Kishor Kumar

Year: 2021

Venue: Polymers

DOI: https://doi.org/10.3390/polym13071105

Paper Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

Ganesan, Anand K.; Ho, Hsiang; Bodemann, Brian O. et al. · 2008 · PLoS Genetics · DOI

Full title: Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

Authors: Ganesan, Anand K.; Ho, Hsiang; Bodemann, Brian O.; Petersen, Sean; Aruri, Jayavani; Koshy, Shiney; Richardson, Zachary; Le, Lu Q.; Krasieva, Tatiana B.; Roth, Michael G.; Farmer, Patrick J.; White, Michael A.

Year: 2008

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1000298

Paper Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

Spaeth, Erika L.; Dembinski, Jennifer L.; Sasser, A. Kate et al. · 2009 · PLoS ONE · DOI

Full title: Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

Authors: Spaeth, Erika L.; Dembinski, Jennifer L.; Sasser, A. Kate; Watson, Keri; Klopp, Ann H.; Hall, Brett M.; Andreeff, Michael; Marini, Frank C.

Year: 2009

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0004992

Paper Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

Löscher, Wolfgang; Potschka, Heidrun · 2004 · NeuroRx · DOI

Full title: Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

Authors: Löscher, Wolfgang; Potschka, Heidrun

Year: 2004

Venue: NeuroRx

DOI: https://doi.org/10.1602/neurorx.2.1.86

Paper Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery

Alavijeh, Mohammad S.; Chishty, Mansoor; Qaiser, M. Zeeshan et al. · 2005 · NeuroRx · DOI

Full title: Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery

Authors: Alavijeh, Mohammad S.; Chishty, Mansoor; Qaiser, M. Zeeshan; Palmer, Alan M.

Year: 2005

Venue: NeuroRx

DOI: https://doi.org/10.1602/neurorx.2.4.554

Paper Magnetic nanoparticles for gene and drug delivery

Dobson, Jon · 2008 · International Journal of Nanomedicine · DOI

Full title: Magnetic nanoparticles for gene and drug delivery

Authors: Dobson, Jon

Year: 2008

Venue: International Journal of Nanomedicine

DOI: https://doi.org/10.2147/ijn.s1608

Paper Is It Time to Start Transitioning From 2D to 3D Cell Culture?

Jensen, Caleb; Teng, Yong · 2020 · Frontiers in Molecular Biosciences · DOI

Full title: Is It Time to Start Transitioning From 2D to 3D Cell Culture?

Authors: Jensen, Caleb; Teng, Yong

Year: 2020

Venue: Frontiers in Molecular Biosciences

DOI: https://doi.org/10.3389/fmolb.2020.00033

Paper Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Szymański, Paweł; Markowicz-Piasecka, Magdalena; Mikiciuk‐Olasik, Elżbieta · 2011 · International Journal of Molecular Sciences · DOI

Full title: Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Authors: Szymański, Paweł; Markowicz-Piasecka, Magdalena; Mikiciuk‐Olasik, Elżbieta

Year: 2011

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms13010427

Paper Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Jurga, Agnieszka M.; Paleczna, Martyna; Kuter, Katarzyna · 2020 · Frontiers in Cellular Neuroscience · DOI

Full title: Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Authors: Jurga, Agnieszka M.; Paleczna, Martyna; Kuter, Katarzyna

Year: 2020

Venue: Frontiers in Cellular Neuroscience

DOI: https://doi.org/10.3389/fncel.2020.00198

Paper In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform

Katt, Moriah E.; Placone, Amanda L.; Wong, Andrew D. et al. · 2016 · Frontiers in Bioengineering and Biotechnology · DOI

Full title: In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform

Authors: Katt, Moriah E.; Placone, Amanda L.; Wong, Andrew D.; Xu, Zinnia S.; Searson, Peter C.

Year: 2016

Venue: Frontiers in Bioengineering and Biotechnology

DOI: https://doi.org/10.3389/fbioe.2016.00012

Paper Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Berg, Ellen L. · 2019 · Frontiers in Big Data · DOI

Full title: Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Authors: Berg, Ellen L.

Year: 2019

Venue: Frontiers in Big Data

DOI: https://doi.org/10.3389/fdata.2019.00047

Paper Advances in Skin Regeneration Using Tissue Engineering

Vig, Komal; Chaudhari, Atul A.; Tripathi, Shweta et al. · 2017 · International Journal of Molecular Sciences · DOI

Full title: Advances in Skin Regeneration Using Tissue Engineering

Authors: Vig, Komal; Chaudhari, Atul A.; Tripathi, Shweta; Dixit, Saurabh; Sahu, Rajnish; Pillai, Shreekumar; Dennis, Vida A.; Singh, Shree R.

Year: 2017

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms18040789

Paper Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

Cheung, Randy Chi Fai; Ng, Tzi Bun; Wong, Jack Ho et al. · 2015 · Marine Drugs · DOI

Full title: Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

Authors: Cheung, Randy Chi Fai; Ng, Tzi Bun; Wong, Jack Ho; Chan, Wai‐Yee

Year: 2015

Venue: Marine Drugs

DOI: https://doi.org/10.3390/md13085156

Paper Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Tottoli, Erika Maria; Dorati, Rossella; Genta, Ida et al. · 2020 · Pharmaceutics · DOI

Full title: Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Authors: Tottoli, Erika Maria; Dorati, Rossella; Genta, Ida; Chiesa, Enrica; Pisani, Silvia; Conti, Bice

Year: 2020

Venue: Pharmaceutics

DOI: https://doi.org/10.3390/pharmaceutics12080735

Paper Alginate-Based Biomaterials for Regenerative Medicine Applications

Sun, Jinchen; Tan, Huaping · 2013 · Materials · DOI

Full title: Alginate-Based Biomaterials for Regenerative Medicine Applications

Authors: Sun, Jinchen; Tan, Huaping

Year: 2013

Venue: Materials

DOI: https://doi.org/10.3390/ma6041285

Paper A framework for advancing our understanding of cancer-associated fibroblasts

Sahai, Erik; Astsaturov, Igor; Cukierman, Edna et al. · 2020 · Nature reviews. Cancer · DOI

Full title: A framework for advancing our understanding of cancer-associated fibroblasts

Authors: Sahai, Erik; Astsaturov, Igor; Cukierman, Edna; DeNardo, David G.; Egeblad, Mikala; Evans, Ronald M.; Fearon, Douglas T.; Greten, Florian R.; Hingorani, Sunil R.; Hunter, Tony; Hynes, Richard O.; Jain, Rakesh K.; Janowitz, Tobias; Jørgensen, Claus; Kimmelman, Alec C.; Kolonin, Mikhail G.; Maki, Robert G.; Powers, Scott; Puré, Ellen; Ramirez, Daniel C.; Scherz‐Shouval, Ruth; Sherman, Mara H.; Stewart, Sheila A.; Tlsty, Thea D.; Tuveson, David A.; Watt, Fiona M.; Weaver, Valerie M.; Weeraratna, Ashani T.; Werb, Zena

Year: 2020

Venue: Nature reviews. Cancer

DOI: https://doi.org/10.1038/s41568-019-0238-1

Paper Challenges to curing primary brain tumours

Aldape, Kenneth; Brindle, Kevin M.; Chesler, Louis et al. · 2019 · Nature Reviews Clinical Oncology · DOI

Full title: Challenges to curing primary brain tumours

Authors: Aldape, Kenneth; Brindle, Kevin M.; Chesler, Louis; Chopra, Rajesh; Gajjar, Amar; Gilbert, Mark R.; Gottardo, Nicholas G.; Gutmann, David H.; Hargrave, Darren; Holland, Eric C.; Jones, David; Joyce, Johanna A.; Kearns, Pamela; Kieran, Mark W.; Mellinghoff, Ingo K.; Merchant, Melinda S.; Pfister, Stefan M.; Pollard, Steven M.; Ramaswamy, Vijay; Rich, Jeremy N.; Robinson, Giles; Rowitch, David H.; Sampson, John H.; Taylor, Michael D.; Workman, Paul; Gilbertson, Richard J.

Year: 2019

Venue: Nature Reviews Clinical Oncology

DOI: https://doi.org/10.1038/s41571-019-0177-5

Paper Engineering dendritic cell vaccines to improve cancer immunotherapy

Perez, Caleb R.; Palma, Michele De · 2019 · Nature Communications · DOI

Full title: Engineering dendritic cell vaccines to improve cancer immunotherapy

Authors: Perez, Caleb R.; Palma, Michele De

Year: 2019

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-019-13368-y

Paper Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells

Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J. et al. · 2018 · Nature Communications · DOI

Full title: Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells

Authors: Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J.; Hogeweg, Mark; Jansen, Pascal W.T.C.; Middelwijk, Jesse; Steen, Ruud van der; Vermeulen, Michiel; Stunnenberg, Hendrik G.; Albers, Cornelis A.; Mulder, Klaas W.

Year: 2018

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-018-04761-0

Paper Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Chen, Min; Yao, Chencheng; Qin, Yingying et al. · 2022 · Signal Transduction and Targeted Therapy · DOI

Full title: Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Authors: Chen, Min; Yao, Chencheng; Qin, Yingying; Cui, Xiuhong; Li, Peng; Ji, Zhiyong; Lin, Limei; Wu, Haowei; Zhou, Zhi; Gui, Yaoting; Li, Zheng; Gao, Fei

Year: 2022

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00710-4

Paper Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, Marta; Menon, Vilas; Habib, Naomi et al. · 2020 · Nature Communications · DOI

Full title: Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Authors: Olah, Marta; Menon, Vilas; Habib, Naomi; Taga, Mariko; Ma, Yiyi; Yung, Christina; Cimpean, Maria; Khairallah, Anthony; Coronas‐Samano, Guillermo; Sankowski, Roman; Grün, Dominic; Kroshilina, Alexandra; Dionne, Danielle; Sarkis, Rani A.; Cosgrove, G. Rees; Helgager, Jeffrey; Golden, Jeffrey A.; Pennell, Page B.; Prinz, Marco; Vonsattel, Jean Paul; Teich, Andrew F.; Schneider, Julie A.; Bennett, David A.; Regev, Aviv; Elyaman, Wassim; Bradshaw, Elizabeth M.; Jager, Philip L. De

Year: 2020

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-020-19737-2

Paper A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Gordon, David E.; Jang, Gwendolyn Μ.; Bouhaddou, Mehdi et al. · 2020 · Nature · DOI

Full title: A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Authors: Gordon, David E.; Jang, Gwendolyn Μ.; Bouhaddou, Mehdi; Xu, Jiewei; Obernier, Kirsten; White, Kris M.; O’Meara, Matthew J.; Rezelj, Veronica V.; Guo, Jeffrey; Swaney, Danielle L.; Tummino, Tia A.; Hüttenhain, Ruth; Kaake, Robyn M.; Richards, Alicia; Tutuncuoglu, Beril; Foussard, Helene; Batra, Jyoti; Haas, Kelsey M.; Modak, Maya; Kim, Minkyu; Haas, Paige; Polacco, Benjamin J.; Braberg, Hannes; Fabius, Jacqueline M.; Eckhardt, Manon; Soucheray, Margaret; Bennett, Melanie J.; Çakır, Merve; McGregor, Michael; Li, Qiongyu; Meyer, Bjoern; Roesch, Ferdinand; Vallet, Thomas; Kain, Alice Mac; Miorin, Lisa; Moreno, Elena; Naing, Zun Zar Chi; Zhou, Yuan; Peng, Shiming; Shi, Ying; Zhang, Ziyang; Shen, Wenqi; Kirby, Ilsa T.; Melnyk, James E.; Chorba, John S.; Lou, Kevin; Dai, Shizhong; Barrio‐Hernandez, Inigo; Memon, Danish; Hernández-Armenta, Claudia; Lyu, Jiankun; Mathy, Christopher J.P.; Perica, Tina; Pilla, Kala Bharath; Ganesan, Sai J.; Saltzberg, Daniel J.; Rakesh, Ramachandran; Xi, Liu; Rosenthal, Sara Brin; Calviello, Lorenzo; Venkataramanan, Srivats; Liboy-Lugo, José; Lin, Yizhu; Huang, Xi‐Ping; Liu, Yongfeng; Wankowicz, Stephanie A.; Bohn, Markus‐Frederik; Safari, Maliheh; Ugur, Fatima S.; Koh, Cassandra; Savar, Nastaran Sadat; Tran, Quang; Shengjuler, Djoshkun; Fletcher, Sabrina Johanna; O’Neal, Michael C.; Cai, Yiming; Chang, Jason C.; Broadhurst, David; Klippsten, Saker; Sharp, Phillip P.; Wenzell, Nicole A.; Kuzuoğlu‐Öztürk, Duygu; Wang, Hao‐Yuan; Trenker, Raphael; Young, Janet M.; Cavero, Devin A.; Hiatt, Joseph; Roth, Theodore L.; Rathore, Ujjwal; Subramanian, Advait; Noack, Julia; Hubert, Mathieu; Stroud, Robert M.; Frankel, Alan D.; Rosenberg, Oren S.; Verba, Kliment A.; Agard, David A.; Ott, Mélanie; Emerman, Michael; Jura, Natalia

Year: 2020

Venue: Nature

DOI: https://doi.org/10.1038/s41586-020-2286-9

Paper Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

Smits, Jos P.H.; Niehues, Hanna; Rikken, Gijs et al. · 2017 · Scientific Reports · DOI

Full title: Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

Authors: Smits, Jos P.H.; Niehues, Hanna; Rikken, Gijs; Vlijmen‐Willems, Ivonne M.J.J. van; Zande, Guillaume W. H. J. F. van de; Zeeuwen, Patrick L.J.M.; Schalkwijk, Joost; Bogaard, Ellen H. van den

Year: 2017

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-12041-y

Paper Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

Skardal, Aleksander; Murphy, Sean V.; Devarasetty, Mahesh et al. · 2017 · Scientific Reports · DOI

Full title: Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

Authors: Skardal, Aleksander; Murphy, Sean V.; Devarasetty, Mahesh; Mead, Ivy; Kang, Hyun-Wook; Seol, Young-Joon; Zhang, Yu Shrike; Shin, Su-Ryon; Zhao, Liang; Aleman, Julio; Hall, Adam R.; Shupe, Thomas; Kleensang, André; Dokmeci, Mehmet R.; Lee, Sang Jin; Jackson, John D.; Yoo, James J.; Härtung, Thomas; Khademhosseini, Ali; Söker, Shay; Bishop, Colin E.; Atala, Anthony

Year: 2017

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-08879-x

Paper Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram

Biancalani, Tommaso; Scalia, Gabriele; Buffoni, Lorenzo et al. · 2021 · Nature Methods · DOI

Full title: Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram

Authors: Biancalani, Tommaso; Scalia, Gabriele; Buffoni, Lorenzo; Avasthi, Raghav; Lu, Ziqing; Sanger, Aman; Tokcan, Neriman; Vanderburg, Charles; Segerstolpe, Åsa; Zhang, Meng; Avraham‐Davidi, Inbal; Vicković, Sanja; Nitzan, Mor; Ma, Sai; Subramanian, Ayshwarya; Lipiński, Michał; Buenrostro, Jason D.; Brown, Nik Bear; Fanelli, Duccio; Zhuang, Xiaowei; Macosko, Evan Z.; Regev, Aviv

Year: 2021

Venue: Nature Methods

DOI: https://doi.org/10.1038/s41592-021-01264-7

Paper Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Lin, Athena W.; Barradas, Marta; Stone, James C. et al. · 1998 · Genes & Development · DOI

Full title: Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Authors: Lin, Athena W.; Barradas, Marta; Stone, James C.; Aelst, Linda Van; Serrano, Manuel; Lowe, Scott W.

Year: 1998

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.12.19.3008

Paper Immuno-Detection by sequencing (ID-seq) enables large-scale high-dimensional phenotyping in cells

Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J. et al. · 2017 · DOI

Full title: Immuno-Detection by sequencing (ID-seq) enables large-scale high-dimensional phenotyping in cells

Authors: Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J.; Hogeweg, Mark; Middelwijk, Jesse; Steen, Ruud van der; Albers, Cornelis A.; Mulder, Klaas W.

Year: 2017

DOI: https://doi.org/10.1101/158139

Paper Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Ewald, Jessica; Titterton, Katherine; Bäuerle, Alex et al. · 2025 · DOI

Full title: Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Authors: Ewald, Jessica; Titterton, Katherine; Bäuerle, Alex; Beatson, Alex; Boiko, Daniil A; Cabrera, Ángel Alexander; Cheah, Jaime H.; Cimini, Beth A.; Gorissen, Bram L.; Jones, Thouis R.; Karczewski, Jakub; Rouquié, David; Seal, Srijit; Weisbart, Erin; White, Brandon M.; Carpenter, Anne E.; Singh, Shantanu

Year: 2025

DOI: https://doi.org/10.1101/2025.01.22.634152

Paper The Hippo pathway: regulators and regulations

Yu, Fa‐Xing; Guan, Kun‐Liang · 2013 · Genes & Development · DOI

Full title: The Hippo pathway: regulators and regulations

Authors: Yu, Fa‐Xing; Guan, Kun‐Liang

Year: 2013

Venue: Genes & Development

DOI: https://doi.org/10.1101/gad.210773.112

Paper Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

Sukhova, Galina K.; Shi, Guo‐Ping; Simon, Daniel I. et al. · 1998 · Journal of Clinical Investigation · DOI

Full title: Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

Authors: Sukhova, Galina K.; Shi, Guo‐Ping; Simon, Daniel I.; Chapman, Harold A.; Libby, Peter

Year: 1998

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci181

Paper Liver fibrosis

Bataller, Ramón; Brenner, David A. · 2005 · Journal of Clinical Investigation · DOI

Full title: Liver fibrosis

Authors: Bataller, Ramón; Brenner, David A.

Year: 2005

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci24282

Paper Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Kebriaei, Partow; Singh, Harjeet; Huls, M. Helen et al. · 2016 · Journal of Clinical Investigation · DOI

Full title: Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Authors: Kebriaei, Partow; Singh, Harjeet; Huls, M. Helen; Figliola, Matthew J.; Bassett, Roland L.; Olivares, Simon; Jena, Bipulendu; Dawson, Margaret J.; Kumaresan, Pappanaicken R.; Su, Shihuang; Maiti, Sourindra N.; Dai, Jianliang; Moriarity, Branden S.; Forget, Marie-Andrée; Senyukov, Vladimir; Orozco, Aaron; Liu, Tingting; McCarty, Jessica M; Jackson, Rineka N.; Moyes, Judy S.; Rondón, Gabriela; Qazilbash, Muzaffar H.; Ciurea, Stefan O.; Alousi, Amin M.; Nieto, Yago; Rezvani, Katy; Marín, David; Popat, Uday; Hosing, Chitra; Shpall, Elizabeth J.; Kantarjian, Hagop M.; Keating, Michael J.; Wierda, William G.; Do, Kim‐Anh; Largaespada, David A.; Lee, Dean A.; Hackett, Perry B.; Champlin, Richard E.; Cooper, Laurence J.N.

Year: 2016

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci86721

Paper Generation and testing of clinical-grade exosomes for pancreatic cancer

Mendt, Mayela Carolina; Kamerkar, Sushrut; Sugimoto, Hikaru et al. · 2018 · JCI Insight · DOI

Full title: Generation and testing of clinical-grade exosomes for pancreatic cancer

Authors: Mendt, Mayela Carolina; Kamerkar, Sushrut; Sugimoto, Hikaru; McAndrews, Kathleen M.; Wu, Chia-Chin; Gagea, Mihai; Yang, Sujuan; Blanko, Elena V. Rodriges; Peng, Qian; Ma, Xiaoyan; Marszalek, Joseph R.; Maitra, Anirban; Yee, Cassian; Rezvani, Katayoun; Shpall, Elizabeth J.; LeBleu, Valerie S.; Kalluri, Raghu

Year: 2018

Venue: JCI Insight

DOI: https://doi.org/10.1172/jci.insight.99263

Paper Bone regeneration: current concepts and future directions

Dimitriou, Rozalia; Jones, Elena; McGonagle, Dennis et al. · 2011 · BMC Medicine · DOI

Full title: Bone regeneration: current concepts and future directions

Authors: Dimitriou, Rozalia; Jones, Elena; McGonagle, Dennis; Giannoudis, Peter V.

Year: 2011

Venue: BMC Medicine

DOI: https://doi.org/10.1186/1741-7015-9-66

Paper The hCMEC/D3 cell line as a model of the human blood brain barrier

Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre‐Olivier · 2013 · Fluids and Barriers of the CNS · DOI

Full title: The hCMEC/D3 cell line as a model of the human blood brain barrier

Authors: Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre‐Olivier

Year: 2013

Venue: Fluids and Barriers of the CNS

DOI: https://doi.org/10.1186/2045-8118-10-16

Paper ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

Hinderliter, Paul M.; Minard, Kevin R.; Orr, Galya et al. · 2010 · Particle and Fibre Toxicology · DOI

Full title: ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

Authors: Hinderliter, Paul M.; Minard, Kevin R.; Orr, Galya; Chrisler, William; Thrall, Brian D.; Pounds, Joel G.; Teeguarden, Justin

Year: 2010

Venue: Particle and Fibre Toxicology

DOI: https://doi.org/10.1186/1743-8977-7-36

Paper Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Vinci, Maria; Gowan, Sharon; Boxall, Frances et al. · 2012 · BMC Biology · DOI

Full title: Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Authors: Vinci, Maria; Gowan, Sharon; Boxall, Frances; Patterson, Lisa; Zimmermann, Miriam; Court, William; Lomas, C.; Mendiola, Marta; Hardisson, David; Eccles, Suzanne A.

Year: 2012

Venue: BMC Biology

DOI: https://doi.org/10.1186/1741-7007-10-29

Paper Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Woodruff, Trent M.; Thundyil, John; Tang, Sung‐Chun et al. · 2011 · Molecular Neurodegeneration · DOI

Full title: Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Authors: Woodruff, Trent M.; Thundyil, John; Tang, Sung‐Chun; Sobey, Christopher G.; Taylor, Stephen M.; Arumugam, Thiruma V.

Year: 2011

Venue: Molecular Neurodegeneration

DOI: https://doi.org/10.1186/1750-1326-6-11

Paper CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Carpenter, Anne E.; Jones, Thouis R.; Lamprecht, Michael R. et al. · 2006 · Genome biology · DOI

Full title: CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Authors: Carpenter, Anne E.; Jones, Thouis R.; Lamprecht, Michael R.; Clarke, Colin; Kang, In Han; Friman, Ola; Guertin, David A.; Chang, Joseph; Lindquist, Robert A.; Moffat, Jason; Golland, Polina; Sabatini, David M.

Year: 2006

Venue: Genome biology

DOI: https://doi.org/10.1186/gb-2006-7-10-r100

Paper Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Seyhan, Attila A. · 2019 · Translational Medicine Communications · DOI

Full title: Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Authors: Seyhan, Attila A.

Year: 2019

Venue: Translational Medicine Communications

DOI: https://doi.org/10.1186/s41231-019-0050-7

Paper Organ-on-a-chip: recent breakthroughs and future prospects

Wu, Qirui; Liu, Jinfeng; Wang, Xiaohong et al. · 2020 · BioMedical Engineering OnLine · DOI

Full title: Organ-on-a-chip: recent breakthroughs and future prospects

Authors: Wu, Qirui; Liu, Jinfeng; Wang, Xiaohong; Feng, Lingyan; Wu, Jinbo; Zhu, Xiaoli; Wen, Weijia; Gong, Xiuqing

Year: 2020

Venue: BioMedical Engineering OnLine

DOI: https://doi.org/10.1186/s12938-020-0752-0

Paper Tumor microenvironment complexity and therapeutic implications at a glance

Baghban, Roghayyeh; Roshangar, Leila; Jahanban‐Esfahlan, Rana et al. · 2020 · Cell Communication and Signaling · DOI

Full title: Tumor microenvironment complexity and therapeutic implications at a glance

Authors: Baghban, Roghayyeh; Roshangar, Leila; Jahanban‐Esfahlan, Rana; Seidi, Khaled; Ebrahimi‐Kalan, Abbas; Jaymand, Mehdi; Kolahian, Saeed; Javaheri, Tahereh; Zare, Payman

Year: 2020

Venue: Cell Communication and Signaling

DOI: https://doi.org/10.1186/s12964-020-0530-4

Paper Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Abasalizadeh, Farhad; Moghaddam, Sevil Vaghefi; Alizadeh, Effat et al. · 2020 · Journal of Biological Engineering · DOI

Full title: Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Authors: Abasalizadeh, Farhad; Moghaddam, Sevil Vaghefi; Alizadeh, Effat; Akbari, Elahe; Kashani, Elmira; Fazljou, Seyyed Mohammad Bagher; Torbati, Mohammadali; Akbarzadeh, Abolfazl

Year: 2020

Venue: Journal of Biological Engineering

DOI: https://doi.org/10.1186/s13036-020-0227-7

Paper 3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Zanoni, Michele; Piccinini, Filippo; Arienti, Chiara et al. · 2016 · Scientific Reports · DOI

Full title: 3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Authors: Zanoni, Michele; Piccinini, Filippo; Arienti, Chiara; Zamagni, Alice; Santi, Spartaco; Polico, R.; Bevilacqua, Alessandro; Tesei, Anna

Year: 2016

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep19103

Paper Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

Mathur, Anurag; Loskill, Peter; Shao, Kaifeng et al. · 2015 · Scientific Reports · DOI

Full title: Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

Authors: Mathur, Anurag; Loskill, Peter; Shao, Kaifeng; Huebsch, Nathaniel; Hong, SoonGweon; Marcus, Sivan G.; Marks, Natalie C.; Mandegar, Mohammad A.; Conklin, Bruce R.; Lee, Luke P.; Healy, Kevin E.

Year: 2015

Venue: Scientific Reports

DOI: https://doi.org/10.1038/srep08883

Paper Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

Herland, Anna; Meer, Andries D. van der; Fitzgerald, Edward A. et al. · 2016 · PLoS ONE · DOI

Full title: Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

Authors: Herland, Anna; Meer, Andries D. van der; Fitzgerald, Edward A.; Park, Tae‐Eun; Sleeboom, Jelle J. F.; Ingber, Donald E.

Year: 2016

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0150360

Thesis Utilization of Intestinal Monolayers to Study Stem Cell Differentiation and Drug Toxicity

Bieber, Jake Matthew · 2022 · University of California, San Francisco (UCSF) · DOI

Full title: Utilization of Intestinal Monolayers to Study Stem Cell Differentiation and Drug Toxicity

Authors: Bieber, Jake Matthew

Year: 2022

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/0g03x9zz

Thesis In Vitro Modeling of the Kidney for Drug Transport and Toxicity Testing

Jayagopal, Aishwarya · 2017 · University of California, San Francisco (UCSF) · DOI

Full title: In Vitro Modeling of the Kidney for Drug Transport and Toxicity Testing

Authors: Jayagopal, Aishwarya

Year: 2017

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/4tc82959

Thesis Development of micro-physiological multi-organ-on-chip platforms

Agrawal, Gaurav · 2018 · University of California, San Diego (UCSD) · DOI

Full title: Development of micro-physiological multi-organ-on-chip platforms

Authors: Agrawal, Gaurav

Year: 2018

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/68k0q8ph

Thesis Stem cell derived organoids and RNA virus pathogenesis

Simoneau, Camille · 2021 · University of California, San Francisco (UCSF) · DOI

Full title: Stem cell derived organoids and RNA virus pathogenesis

Authors: Simoneau, Camille

Year: 2021

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/3sw4926b

Thesis 3D BioPrinting of Cardiac Micro-Tissues

Kleinemolen, Kathleen · 2021 · University of California, San Diego (UCSD) · DOI

Full title: 3D BioPrinting of Cardiac Micro-Tissues

Authors: Kleinemolen, Kathleen

Year: 2021

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/53x8j44b

Thesis Development of Tools for Whole-Organism High-Throughput Screening

Liu, Harrison Yi · 2016 · University of California, San Francisco (UCSF) · DOI

Full title: Development of Tools for Whole-Organism High-Throughput Screening

Authors: Liu, Harrison Yi

Year: 2016

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/8bn862xw

Thesis Development of 3D Cell-Based Assay for High Throughput Screening of Cancer Drugs

Xin, Xin · 2017 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Development of 3D Cell-Based Assay for High Throughput Screening of Cancer Drugs

Authors: Xin, Xin

Year: 2017

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1492700405342723

Thesis Modeling Liver Diseases Using Hepatic Cell Microarrays

Roth, Alexander David · 2018 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Modeling Liver Diseases Using Hepatic Cell Microarrays

Authors: Roth, Alexander David

Year: 2018

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=csu1544719407531728

Thesis Evaluating the use of Cryopreserved Hepatocytes for the Prediction of In Vivo Hepatic Clearance

Eng, Heather S. · 2004 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Evaluating the use of Cryopreserved Hepatocytes for the Prediction of In Vivo Hepatic Clearance

Authors: Eng, Heather S.

Year: 2004

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=toledo1091638312

Thesis In vitro 3D fluorescent cell-based assay reporting gene regulation for high-throughput drug screening

Li, You · 2022 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: In vitro 3D fluorescent cell-based assay reporting gene regulation for high-throughput drug screening

Authors: Li, You

Year: 2022

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1650589879349223

Thesis Statistical Analysis of High Content Screening Data

Jacques, Richard · 2009 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Statistical Analysis of High Content Screening Data

Authors: Jacques, Richard

Year: 2009

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/2220/2/Jacques%2C_Richard.pdf

Thesis Validation of a Human B-Cell Model to Evaluate Potential Immunotoxicants

Rachakonda, Venkata Sailaja · 2025 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Validation of a Human B-Cell Model to Evaluate Potential Immunotoxicants

Authors: Rachakonda, Venkata Sailaja

Year: 2025

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=wright1748670629711161

Thesis High-capacity in vitro models for the assessment of pain-related mechanisms

Lydia Moll (18643606) · 2024 · Karolinska Institutet · DOI

Full title: High-capacity in vitro models for the assessment of pain-related mechanisms

Authors: Lydia Moll (18643606)

Year: 2024

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26899609

Thesis 3-D cell-based high-throughput screening for drug discovery and cell culture process development

Zhang, Xudong · 2008 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: 3-D cell-based high-throughput screening for drug discovery and cell culture process development

Authors: Zhang, Xudong

Year: 2008

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561

Thesis Generation of an optimized model of iPSC-derived human intestinal organoids for the expression of an intestinal stem cell fluorescent reporter, and a preliminary assessment for its application in high-throughput screening

Wong Valencia, Christian Eduardo · 2021 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Generation of an optimized model of iPSC-derived human intestinal organoids for the expression of an intestinal stem cell fluorescent reporter, and a preliminary assessment for its application in high-throughput screening

Authors: Wong Valencia, Christian Eduardo

Year: 2021

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/28701/1/Thesis%20CE%20Wong%20Valencia.pdf

Thesis Extrapolating from experimental to human studies via the in vitro paradigm

Bowen, Edward Llewellyn · 2015 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Extrapolating from experimental to human studies via the in vitro paradigm

Authors: Bowen, Edward Llewellyn

Year: 2015

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/12539/1/E.L.Bowen%20thesis%20v7.pdf

Thesis Development of a Gut-on-a-Chip models in a 3D microfluidic platform (OrganoPlate®)

Naumovska, Elena · 2020 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Development of a Gut-on-a-Chip models in a 3D microfluidic platform (OrganoPlate®)

Authors: Naumovska, Elena

Year: 2020

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/26679/1/20200406%20thesis%20v.3%20Final.pdf

Thesis Human iPSC derived neural cells as models of brain development and as tools in pharmaceutical drug discovery

Anders Lundin (18691306) · 2018 · Karolinska Institutet · DOI

Full title: Human iPSC derived neural cells as models of brain development and as tools in pharmaceutical drug discovery

Authors: Anders Lundin (18691306)

Year: 2018

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26917729

Thesis Hepatic 3D spheroids as a model system for drug-induced liver injury and cytochrome P450 induction

Delilah Hendriks (18678418) · 2018 · Karolinska Institutet · DOI

Full title: Hepatic 3D spheroids as a model system for drug-induced liver injury and cytochrome P450 induction

Authors: Delilah Hendriks (18678418)

Year: 2018

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26906974

Thesis Development of an immune competent human skin equivalent model of atopic dermatitis for pre-clinical drug testing

Barragan Vazquez, Inmaculada · 2022 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Development of an immune competent human skin equivalent model of atopic dermatitis for pre-clinical drug testing

Authors: Barragan Vazquez, Inmaculada

Year: 2022

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/32613/1/Barragan%20Vazquez_Inmaculada_180112272.pdf

Thesis Novel human in vitro systems for studies of drug inducted hepatotoxicity

Louise Sivertsson (18678481) · 2012 · Karolinska Institutet · DOI

Full title: Novel human in vitro systems for studies of drug inducted hepatotoxicity

Authors: Louise Sivertsson (18678481)

Year: 2012

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26898070

Thesis The In Vitro Pharmacology of Cannabidivarin (CBDV)

Le, Jennifer · 2023 · University of Saskatchewan - HARVEST · DOI

Full title: The In Vitro Pharmacology of Cannabidivarin (CBDV)

Authors: Le, Jennifer

Year: 2023

Venue: University of Saskatchewan - HARVEST

DOI: https://hdl.handle.net/10388/14711

Thesis Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Gagg, Hannah Jane · 2023 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Authors: Gagg, Hannah Jane

Year: 2023

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/35177/1/HannahGagg_Thesis_Final_JULY24.pdf

Thesis Danio rerio as a model of serious human diseases

Hason, Martina · 2022 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Danio rerio as a model of serious human diseases

Authors: Hason, Martina

Year: 2022

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/175636

Thesis Defined matrices for epithelial organoid culture and disease modelling

Rezakhani, Saba · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Defined matrices for epithelial organoid culture and disease modelling

Authors: Rezakhani, Saba

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/181177

Thesis Design and validation of bioorthogonal probes for cellular disease models

D'Alessandro, Pier Luca · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Design and validation of bioorthogonal probes for cellular disease models

Authors: D'Alessandro, Pier Luca

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/162248

Thesis Intestinal stem cells differentiation and its application in cancer therapy

Norkin, Maxim · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Intestinal stem cells differentiation and its application in cancer therapy

Authors: Norkin, Maxim

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/183214

Thesis Bioengineering functional organoid models across scales

Hübscher, Tania · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineering functional organoid models across scales

Authors: Hübscher, Tania

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/207102

Thesis Bioengineering approaches to emulate the stem cell niche

Höhnel, Sylke · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineering approaches to emulate the stem cell niche

Authors: Höhnel, Sylke

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/110539

Thesis Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

Woodruff, Kristina Pan · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

Authors: Woodruff, Kristina Pan

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/141458

Thesis Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

May, LT; Bartolo, BA; Harrison, DG et al. · 2023 · University of Melbourne · DOI

Full title: Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

Authors: May, LT; Bartolo, BA; Harrison, DG; Guzik, T; Drummond, GR; Figtree, GA; Ritchie, RH; Rye, KA; De Haan, JB

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/334908

Thesis Optimizing Stem Cell Models of the Human Gut-immune Barriers

Piryaei, Masoumeh · 2024 · University of Melbourne · DOI

Full title: Optimizing Stem Cell Models of the Human Gut-immune Barriers

Authors: Piryaei, Masoumeh

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/345315

Thesis Novel approaches using human induced pluripotent stem cells and microRNAs in the development of relevant human hepatocyte models for drug-induced liver injury

Kia, Richard · University of Liverpool · DOI

Full title: Novel approaches using human induced pluripotent stem cells and microRNAs in the development of relevant human hepatocyte models for drug-induced liver injury

Authors: Kia, Richard

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/2010059/1/KiaRic_Oct2014_2010059.pdf

Thesis Determinants of transcriptional regulation of transport and oxidative processes in human model systems

Williamson, Beth · University of Liverpool · DOI

Full title: Determinants of transcriptional regulation of transport and oxidative processes in human model systems

Authors: Williamson, Beth

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/15053/1/WilliamsonBet_Sep2013_15053.pdf

Thesis The role of non-myocytes in drug-induced cardiovascular toxicity

Ravenscroft, Stephanie · University of Liverpool · DOI

Full title: The role of non-myocytes in drug-induced cardiovascular toxicity

Authors: Ravenscroft, Stephanie

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/2012640/1/RavenscroftSte_Oct2014_2012639_.pdf

Thesis Development of a Spheroid Model to Investigate Drug-Induced Liver Injury

Gaskell, H · 2016 · University of Liverpool · DOI

Full title: Development of a Spheroid Model to Investigate Drug-Induced Liver Injury

Authors: Gaskell, H

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3004330/1/200648599_Aug2016.pdf

Thesis DEVELOPMENT OF NOVEL PROXIMAL TUBULE IN VITRO MODELS TO PREDICT DRUG-INDUCED NEPHROTOXICITY

Tort Piella, A · 2016 · University of Liverpool · DOI

Full title: DEVELOPMENT OF NOVEL PROXIMAL TUBULE IN VITRO MODELS TO PREDICT DRUG-INDUCED NEPHROTOXICITY

Authors: Tort Piella, A

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3004444/1/200943662_May2016.pdf

Thesis Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Bulitta, Jurgen B; Hope, William W; Eakin, Ann E et al. · 2019 · University of Liverpool · DOI

Full title: Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Authors: Bulitta, Jurgen B; Hope, William W; Eakin, Ann E; Guina, Tina; Tam, Vincent H; Louie, Arnold; Drusano, George L; Hoover, Jennifer L

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3035713/1/AAC.02307-18.full.pdf

Thesis Investigating novel methods of enhancing in vitro models of drug induced liver injury

Heslop, James · 2015 · University of Liverpool · DOI

Full title: Investigating novel methods of enhancing in vitro models of drug induced liver injury

Authors: Heslop, James

Year: 2015

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/2053229/1/HeslopJam_Oct2015_2053229.pdf

Thesis Development of stem cell-derived hepatocyte models

Pridgeon, CS · 2019 · University of Liverpool · DOI

Full title: Development of stem cell-derived hepatocyte models

Authors: Pridgeon, CS

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3060785/1/201067795_Aug2019.pdf

Thesis Developing three-dimensional co-cultures of the small intestinal epithelium with intestinal dendritic cells as a disease model for enteric infections

Johnston, L · 2018 · University of Liverpool · DOI

Full title: Developing three-dimensional co-cultures of the small intestinal epithelium with intestinal dendritic cells as a disease model for enteric infections

Authors: Johnston, L

Year: 2018

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3029488/1/200566317_Sept2018.pdf

Thesis Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E et al. · 2020 · University of Liverpool · DOI

Full title: Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Authors: Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E; Copple, Ian M; Gerets, Helga HJ; Goldring, Christopher E; Guillouzo, Andre; Hewitt, Philip G; Ingelman-Sundberg, Magnus; Jensen, Klaus Gjervig; Juhila, Satu; Klingmueller, Ursula; Labbe, Gilles; Liguori, Michael J; Lovatt, Cerys A; Morgan, Paul; Naisbitt, Dean J; Pieters, Raymond HH; Snoeys, Jan; van de Water, Bob; Williams, Dominic P; Park, B Kevin

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3067231/1/NRDD-18-102V7.pdf

Thesis Designing and Utilising an in vitro Model to Investigate Cellular Pathways Involved in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease

Cotton, CV · 2019 · University of Liverpool · DOI

Full title: Designing and Utilising an in vitro Model to Investigate Cellular Pathways Involved in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease

Authors: Cotton, CV

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3044767/1/200162141_Nov2018.pdf

Thesis Bioengineering an Optimised in vitro Model of the Outer Blood-Retinal Barrier Under Diabetic-like Conditions for the Screening of Novel Pharmacological Formulations for Diabetic Retinopathy

Lugano, Gaia · 2023 · University of Liverpool · DOI

Full title: Bioengineering an Optimised in vitro Model of the Outer Blood-Retinal Barrier Under Diabetic-like Conditions for the Screening of Novel Pharmacological Formulations for Diabetic Retinopathy

Authors: Lugano, Gaia

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3170980/1/201456216_Mar2023.pdf

Thesis Evaluating the Role of Mitochondrial Genetics in Adverse-Drug Reactions and the Application of iPSC-Derived Hepatocytes for Modelling Drug-Induced Liver Injury

Cox, Christopher · 2023 · University of Liverpool · DOI

Full title: Evaluating the Role of Mitochondrial Genetics in Adverse-Drug Reactions and the Application of iPSC-Derived Hepatocytes for Modelling Drug-Induced Liver Injury

Authors: Cox, Christopher

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3171039/1/201368508_Sep2022.pdf

Thesis Models of alveolar remodeling in chronic lung disease

Rosmark, Oskar · 2022 · Lund University (LUP) · DOI

Full title: Models of alveolar remodeling in chronic lung disease

Authors: Rosmark, Oskar

Year: 2022

Venue: Lund University (LUP)

DOI: https://lup.lub.lu.se/record/5470e7fe-294e-4fd8-847d-2054d90eaac6

Thesis Towards improved models for the study of the multi-mechanistic toxicity of drug-induced liver injury

Penman, Sophie · 2020 · University of Liverpool · DOI

Full title: Towards improved models for the study of the multi-mechanistic toxicity of drug-induced liver injury

Authors: Penman, Sophie

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3114219/1/200905357_Oct2020.pdf

Thesis Human iPSC-derived cardiomyocytes as platforms for cardiac disease modeling, therapeutic discovery and safety pharmacology

Chen, Zhifen · 2016 · Technical University of Munich (TUM) · DOI

Full title: Human iPSC-derived cardiomyocytes as platforms for cardiac disease modeling, therapeutic discovery and safety pharmacology

Authors: Chen, Zhifen

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1308504

Thesis Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective

Lin, Christine, author; Khetani, Salman R., advisor; Gustafson, Daniel, committee member et al. · 2018 · Colorado State University · DOI

Full title: Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective

Authors: Lin, Christine, author; Khetani, Salman R., advisor; Gustafson, Daniel, committee member; Kipper, Matthew, committee member; Pagliassotti, Michael, committee member

Year: 2018

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/189267

Thesis Engineering in vitro models of non-alcoholic fatty liver disease

Davidson, Matthew David, author; Khetani, Salman R., advisor; Chicco, Adam J., committee member et al. · 2017 · Colorado State University · DOI

Full title: Engineering in vitro models of non-alcoholic fatty liver disease

Authors: Davidson, Matthew David, author; Khetani, Salman R., advisor; Chicco, Adam J., committee member; Donahue, Seth W., committee member; Kota, Arun K., committee member

Year: 2017

Venue: Colorado State University

DOI: http://hdl.handle.net/10217/181309

Thesis Large Scale Integration Of Microengineered Tissue Models For High-Content, High-Throughput Analysis Of Complex Human Physiological Systems

Georgescu, Andrei · 2023 · University of Pennsylvania · DOI

Full title: Large Scale Integration Of Microengineered Tissue Models For High-Content, High-Throughput Analysis Of Complex Human Physiological Systems

Authors: Georgescu, Andrei

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/31621

Thesis Microfluidic culture of human hepatocytes and endothelial cells with applications in drug toxicity screening

Ware, Brenton R., author; Khetani, Salman R., advisor; Gustafson, Daniel L., committee member et al. · 2018 · Colorado State University · DOI

Full title: Microfluidic culture of human hepatocytes and endothelial cells with applications in drug toxicity screening

Authors: Ware, Brenton R., author; Khetani, Salman R., advisor; Gustafson, Daniel L., committee member; Henry, Charles S., committee member; Twedt, David C., committee member

Year: 2018

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/189305

Thesis Three dimensional polymer scaffolds for high throughput cell-based assay systems

Cheng, Ke · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: Three dimensional polymer scaffolds for high throughput cell-based assay systems

Authors: Cheng, Ke

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/11717/files/cheng_ke_200808_phd.pdf

Thesis Brain-on-a-chip toward neurological diseases' drug discovery

Ndyabawe, Kenneth · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: Brain-on-a-chip toward neurological diseases' drug discovery

Authors: Ndyabawe, Kenneth

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/19939/files/ndyabawe_kenneth_201805_phd.pdf

Thesis DEVELOPMENT OF A MICROGLIA MORPHOLOGY-BASED POTENCY ASSAY TO ASSESS THE THERAPEUTIC POTENTIAL OF MESENCHYMAL STROMAL CELL DERIVED-EXTRACELLULAR VESICLES IN THE CONTEXT OF NEUROINFLAMMATION

Daga, Kanupriya Rajesh · 2025 · University of Georgia - UGA Open Scholar · DOI

Full title: DEVELOPMENT OF A MICROGLIA MORPHOLOGY-BASED POTENCY ASSAY TO ASSESS THE THERAPEUTIC POTENTIAL OF MESENCHYMAL STROMAL CELL DERIVED-EXTRACELLULAR VESICLES IN THE CONTEXT OF NEUROINFLAMMATION

Authors: Daga, Kanupriya Rajesh

Year: 2025

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/26932/files/Daga_uga_0077E_16060.pdf

Thesis Neurotoxicity screening using human pluripotent stem cell derived neurons and astrocytes for adverse outcome pathway mapping

Wu, Xian · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: Neurotoxicity screening using human pluripotent stem cell derived neurons and astrocytes for adverse outcome pathway mapping

Authors: Wu, Xian

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/6907/files/wu_xian_201612_phd.pdf

Thesis Neural microtissue engineering for high throughput screening in pre-clinical drug discovery

Lai, Yinzhi · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: Neural microtissue engineering for high throughput screening in pre-clinical drug discovery

Authors: Lai, Yinzhi

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/17693/files/lai_yinzhi_201112_phd.pdf

Thesis Modeling treacher collins syndrome and directed differentiation of brown adipocytes from human pluripotent stem cells

Avery, John Welch III · 2024 · University of Georgia - UGA Open Scholar · DOI

Full title: Modeling treacher collins syndrome and directed differentiation of brown adipocytes from human pluripotent stem cells

Authors: Avery, John Welch III

Year: 2024

Venue: University of Georgia - UGA Open Scholar

DOI: https://openscholar.uga.edu/record/21296/files/avery_john_w_201708_phd.pdf

Thesis An in vitro hybrid method used to model realistic airway deposition and post-deposition behaviour for orally inhaled products

Huynh, Bao Khanh · 2018 · University of Sydney · DOI

Full title: An in vitro hybrid method used to model realistic airway deposition and post-deposition behaviour for orally inhaled products

Authors: Huynh, Bao Khanh

Year: 2018

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/19699

Thesis Developing 3D Models of Paediatric Solid Tumours

Bax, Samuel David Peter · 2025 · University of Sydney · DOI

Full title: Developing 3D Models of Paediatric Solid Tumours

Authors: Bax, Samuel David Peter

Year: 2025

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/33851

Thesis Engineering Culture Conditions of Human Stem Cell-Derived Organoids

Yip, Queenie · 2025 · University of Sydney · DOI

Full title: Engineering Culture Conditions of Human Stem Cell-Derived Organoids

Authors: Yip, Queenie

Year: 2025

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/33859

Thesis In vitro models of the human intestine for better prediction of drug absorption, pre-systemic metabolism, and bioavailability

Ceylan, Merve · 2025 · Uppsala University · DOI

Full title: In vitro models of the human intestine for better prediction of drug absorption, pre-systemic metabolism, and bioavailability

Authors: Ceylan, Merve

Year: 2025

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-551251

Thesis Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

Ölander, Magnus · 2019 · Uppsala University · DOI

Full title: Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

Authors: Ölander, Magnus

Year: 2019

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382406

Thesis ESTIV questionnaire on the acquisition and use of primary human cells and tissue in toxicology

Sladowski, D.; Combes, R.D.; van der Valk, J.B.F. et al. · 2005 · Utrecht University · DOI

Full title: ESTIV questionnaire on the acquisition and use of primary human cells and tissue in toxicology

Authors: Sladowski, D.; Combes, R.D.; van der Valk, J.B.F.; Nawrot, I.; Gut, G.

Year: 2005

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/12169

Thesis Dynamic microphysiological system chip platform for high-throughput, customizable, and multi-dimensional drug screening

Zhu, Yuxuan; Jiang, Deming; Qiu, Yong et al. · 2024 · Nanyang Technological University (NTU) · DOI

Full title: Dynamic microphysiological system chip platform for high-throughput, customizable, and multi-dimensional drug screening

Authors: Zhu, Yuxuan; Jiang, Deming; Qiu, Yong; Liu, Xin; Bian, Yuhan; Tian, Shichao; Wang, Xiandi; Hsia, K. Jimmy; Wan, Hao; Zhuang, Liujing; Wang, Ping

Year: 2024

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/179633

Thesis Regulatory acceptance and use of 3R models: a multilevel perspective

Schiffelers, M.J.W.A.; Blaauboer, B.J.; Hendriksen, C.F.M. et al. · 2012 · Utrecht University · DOI

Full title: Regulatory acceptance and use of 3R models: a multilevel perspective

Authors: Schiffelers, M.J.W.A.; Blaauboer, B.J.; Hendriksen, C.F.M.; Bakker, W.E.

Year: 2012

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/273325

Thesis The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

Blaauboer, B.J.; Boekelheide, K.; Clewell, H.J. et al. · 2012 · Utrecht University · DOI

Full title: The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

Authors: Blaauboer, B.J.; Boekelheide, K.; Clewell, H.J.; Daneshian, M.; Dingemans, M.M.L.; Goldberg, A.M.; Heneweer, M.; Jaworska, J.; Kramer, N.I.; Leist, M.; Seibert, H.; Testai, E.; Vandebriel, R.J.; Yager, J.D.; Zurlo, J.

Year: 2012

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/274139

Thesis Effects of the introducttion of in vitro assays on the use of experimental animals in pharmacological research

Verbost, P.M.; van der Valk, J.B.F.; Hendriksen, C.F.M. · 2007 · Utrecht University · DOI

Full title: Effects of the introducttion of in vitro assays on the use of experimental animals in pharmacological research

Authors: Verbost, P.M.; van der Valk, J.B.F.; Hendriksen, C.F.M.

Year: 2007

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/26133

Thesis Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

Nantasanti, Sathidpak; Spee, Bart; Kruitwagen, Hedwig S et al. · 2015 · Utrecht University · DOI

Full title: Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

Authors: Nantasanti, Sathidpak; Spee, Bart; Kruitwagen, Hedwig S; Chen, Chen; Geijsen, Niels; Oosterhoff, Loes A; van Wolferen, Monique E; Pelaez, Nicolas; Fieten, Hille; Wubbolts, Richard W; Grinwis, Guy C; Chan, Jefferson; Huch, Meritxell; Vries, Robert R G; Clevers, Hans; de Bruin, Alain; Rothuizen, Jan; Penning, Louis C; Schotanus, Baukje A

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/327197

Thesis Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M. et al. · 2011 · Utrecht University · DOI

Full title: Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

Authors: Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M.; Hekkert, M.P.; Schellekens, H.

Year: 2011

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/314494

Thesis Stem Cell-Derived Systems in Toxicology Assessment

Suter-Dick, Laura; Alves, Paula M.; Blaauboer, Bas J. et al. · 2015 · Utrecht University · DOI

Full title: Stem Cell-Derived Systems in Toxicology Assessment

Authors: Suter-Dick, Laura; Alves, Paula M.; Blaauboer, Bas J.; Bremm, Klaus-Dieter; Brito, Catarina; Coecke, Sandra; Flick, Burkhard; Fowler, Paul; Hescheler, Juergen; Ingelman-Sundberg, Magnus; Jennings, Paul; Kelm, Jens M.; Manou, Irene; Mistry, Pratibha; Moretto, Angelo; Roth, Adrian; Stedman, Donald; van de Water, Bob; Beilmann, Mario

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/329523

Thesis Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Broeders, Jessica J W; Parmentier, Céline; Truisi, Germaine L et al. · 2015 · Utrecht University · DOI

Full title: Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Authors: Broeders, Jessica J W; Parmentier, Céline; Truisi, Germaine L; Jossé, Rozenn; Alexandre, Eliane; Savary, Camille C; Hewitt, Philip G; Mueller, Stefan O; Guillouzo, André; Richert, Lysiane; van Eijkeren, Jan C H; Hermens, Joop L M; Blaauboer, Bas J

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/329931

Thesis A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity

Nieskens, Tom T G; Peters, Janny G P; Schreurs, Marieke J et al. · 2016 · Utrecht University · DOI

Full title: A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity

Authors: Nieskens, Tom T G; Peters, Janny G P; Schreurs, Marieke J; Smits, Niels; Woestenenk, Rob; Jansen, Katja; van der Made, Thom K; Röring, Melanie; Hilgendorf, Constanze; Wilmer, Martijn J; Masereeuw, Roos

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/329958

Thesis Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Huch, Meritxell; Gehart, Helmuth; van Boxtel, Ruben et al. · 2015 · Utrecht University · DOI

Full title: Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Authors: Huch, Meritxell; Gehart, Helmuth; van Boxtel, Ruben; Hamer, Karien; Blokzijl, Francis; Verstegen, Monique M. A.; Ellis, Ewa; van Wenum, Martien; Fuchs, Sabine A.; de Ligt, Joep; van de Wetering, Marc; Sasaki, Nobuo; Boers, Susanne J.; Kemperman, Hans; de Jonge, Jeroen; Ijzermans, Jan N. M.; Nieuwenhuis, Edward E. S.; Hoekstra, Ruurdtje; Strom, Stephen; Vries, Robert R. G.; van der Laan, Luc J. W.; Cuppen, Edwin; Clevers, Hans

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/331481

Thesis Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

Trumpi, Kari; Egan, David A.; Vellinga, Thomas T. et al. · 2015 · Utrecht University · DOI

Full title: Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

Authors: Trumpi, Kari; Egan, David A.; Vellinga, Thomas T.; Borel Rinkes, Inne H M; Kranenburg, Onno

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/333255

Thesis Towards Creating the Perfect In Vitro Cell Model

Jonsson, Malin K B; van Veen, AAB; Synnergren, Jane et al. · 2016 · Utrecht University · DOI

Full title: Towards Creating the Perfect In Vitro Cell Model

Authors: Jonsson, Malin K B; van Veen, AAB; Synnergren, Jane; Becker, Bruno

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/343073

Thesis Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J et al. · 2016 · Utrecht University · DOI

Full title: Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Authors: Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J; Kasteel, Emma E J; Hondebrink, Laura; Westerink, Remco H S

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/345305

Thesis Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut

van Rijn, Jorik M; Schneeberger, Kerstin; Wiegerinck, Caroline L et al. · 2016 · Utrecht University · DOI

Full title: Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut

Authors: van Rijn, Jorik M; Schneeberger, Kerstin; Wiegerinck, Caroline L; Nieuwenhuis, Edward E S; Middendorp, Sabine

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/345992

Thesis Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals

Nantasanti, Sathidpak; de Bruin, Alain; Rothuizen, Jan et al. · 2016 · Utrecht University · DOI

Full title: Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals

Authors: Nantasanti, Sathidpak; de Bruin, Alain; Rothuizen, Jan; Penning, Louis C; Schotanus, Baukje A

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/345896

Thesis Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Kruitwagen, Hedwig S.; Oosterhoff, Loes A.; Vernooij, Ingrid G.W.H. et al. · 2017 · Utrecht University · DOI

Full title: Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Authors: Kruitwagen, Hedwig S.; Oosterhoff, Loes A.; Vernooij, Ingrid G.W.H.; Schrall, Ingrid M.; van Wolferen, Monique E.; Bannink, Farah; Roesch, Camille; van Uden, Lisa; Molenaar, Martijn R.; Helms, J. Bernd; Grinwis, Guy C.M.; Verstegen, Monique M.A.; van der Laan, Luc J.W.; Huch, Meritxell; Geijsen, Niels; Vries, Robert G.; Clevers, Hans; Rothuizen, Jan; Schotanus, Baukje A.; Penning, Louis C.; Spee, Bart

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/349600

Thesis Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip

Vriend, Jelle; Nieskens, Tom T G; Vormann, Marianne K et al. · 2018 · Utrecht University · DOI

Full title: Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip

Authors: Vriend, Jelle; Nieskens, Tom T G; Vormann, Marianne K; van den Berge, Bartholomeus T; van den Heuvel, Angelique; Russel, Frans G M; Suter-Dick, Laura; Lanz, Henriëtte L; Vulto, Paul; Masereeuw, Rosalinde; Wilmer, Martijn J

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/368286

Thesis A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of IIon Channels in Real-Time

Goversen, Birgit; Becker, Nadine; Stoelzle-Feix, Sonja et al. · 2018 · Utrecht University · DOI

Full title: A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of IIon Channels in Real-Time

Authors: Goversen, Birgit; Becker, Nadine; Stoelzle-Feix, Sonja; Obergrussberger, Alison; Vos, Marc A; van Veen, Toon A B; Fertig, Niels; de Boer, Teun P

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/363187

Thesis Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

De Sousa, Paul A.; Steeg, Rachel; Wachter, Elisabeth et al. · 2017 · Utrecht University · DOI

Full title: Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

Authors: De Sousa, Paul A.; Steeg, Rachel; Wachter, Elisabeth; Bruce, Kevin; King, Jason; Hoeve, Marieke; Khadun, Shalinee; McConnachie, George; Holder, Julie; Kurtz, Andreas; Seltmann, Stefanie; Dewender, Johannes; Reimann, Sascha; Stacey, Glyn; O'Shea, Orla; Chapman, Charlotte; Healy, Lyn; Zimmermann, Heiko; Bolton, Bryan; Rawat, Trisha; Atkin, Isobel; Veiga, Anna; Kuebler, Bernd; Serano, Blanca Miranda; Saric, Tomo; Hescheler, Jürgen; Brüstle, Oliver; Peitz, Michael; Thiele, Cornelia; Geijsen, Niels; Holst, Bjørn; Clausen, Christian; Lako, Majlinda; Armstrong, Lyle; Gupta, Shailesh K.; Kvist, Alexander J.; Hicks, Ryan; Jonebring, Anna; Brolén, Gabriella; Ebneth, Andreas; Cabrera-Socorro, Alfredo; Foerch, Patrik; Geraerts, Martine; Stummann, Tina C.; Harmon, Shawn; George, Carol; Streeter, Ian; Clarke, Laura; Parkinson, Helen; Harrison, Peter W.; Faulconbridge, Adam; Cherubin, Luca; Burdett, Tony; Trigueros, Cesar; Patel, Minal J.; Lucas, Christa; Hardy, Barry; Predan, Rok; Dokler, Joh; Brajnik, Maja; Keminer, Oliver; Pless, Ole; Gribbon, Philip; Claussen, Carsten; Ringwald, Annette; Kreisel, Beate; Courtney, Aidan; Allsopp, Timothy E.

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/350457

Thesis Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Berkers, Gitte; van Mourik, Peter; Vonk, Annelotte M et al. · 2019 · Utrecht University · DOI

Full title: Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Authors: Berkers, Gitte; van Mourik, Peter; Vonk, Annelotte M; Kruisselbrink, Evelien; Dekkers, Johanna F; de Winter-de Groot, Karin M; Arets, Hubertus G M; Marck-van der Wilt, Rozemarijn E P; Dijkema, Jasper S; Vanderschuren, Maaike M; Houwen, Roderick H J; Heijerman, Harry G M; van de Graaf, Eduard A; Elias, Sjoerd G; Majoor, Christof J; Koppelman, Gerard H; Roukema, Jolt; Bakker, Marleen; Janssens, Hettie M; van der Meer, Renske; Vries, Robert G J; Clevers, Hans C; de Jonge, Hugo R; Beekman, Jeffrey M; van der Ent, Cornelis K

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/378368

Thesis Recellularized native kidney scaffolds as a novel tool in nephrotoxicity screening

Fedecostante, Michele; Westphal, Koen; Buono, Michele et al. · 2018 · Utrecht University · DOI

Full title: Recellularized native kidney scaffolds as a novel tool in nephrotoxicity screening

Authors: Fedecostante, Michele; Westphal, Koen; Buono, Michele; Sanchez Romero, Natalia; Wilmer, Martijn J; Kerkering, Janis; Baptista, Pedro Miguel; Hoenderop, Joost G; Masereeuw, Rosalinde

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/368269

Thesis Advances in predictive in vitro models of drug-induced nephrotoxicity

Soo, Joanne Y-C; Jansen, Jitske; Masereeuw, Rosalinde et al. · 2018 · Utrecht University · DOI

Full title: Advances in predictive in vitro models of drug-induced nephrotoxicity

Authors: Soo, Joanne Y-C; Jansen, Jitske; Masereeuw, Rosalinde; Little, Melissa H

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/369757

Thesis Long-term expanding human airway organoids for disease modeling

Sachs, Norman; Papaspyropoulos, Angelos; Zomer-van Ommen, Domenique D. et al. · 2019 · Utrecht University · DOI

Full title: Long-term expanding human airway organoids for disease modeling

Authors: Sachs, Norman; Papaspyropoulos, Angelos; Zomer-van Ommen, Domenique D.; Heo, Inha; Böttinger, Lena; Klay, Dymph; Weeber, Fleur; Huelsz-Prince, Guizela; Iakobachvili, Nino; Amatngalim, Gimano D.; de Ligt, Joep; van Hoeck, Arne; Proost, Natalie; Viveen, Marco C.; Lyubimova, Anna; Teeven, Luc; Derakhshan, Sepideh; Korving, Jeroen; Begthel, Harry; Dekkers, Johanna F.; Kumawat, Kuldeep; Ramos, Emilio; van Oosterhout, Matthijs F.M.; Offerhaus, G. Johan; Wiener, Dominique J.; Olimpio, Eduardo P.; Dijkstra, Krijn K.; Smit, Egbert F.; van der Linden, Maarten; Jaksani, Sridevi; van de Ven, Marieke; Jonkers, Jos; Rios, Anne C.; Voest, Emile E.; van Moorsel, Coline H.M.; van der Ent, Cornelis K.; Cuppen, Edwin; van Oudenaarden, Alexander; Coenjaerts, Frank E.; Meyaard, Linde; Bont, Louis J.; Peters, Peter J.; Tans, Sander J.; van Zon, Jeroen S.; Boj, Sylvia F.; Vries, Robert G.; Beekman, Jeffrey M.; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/378838

Thesis Tubuloids derived from human adult kidney and urine for personalized disease modeling

Schutgens, Frans; Rookmaaker, Maarten B; Margaritis, Thanasis et al. · 2019 · Utrecht University · DOI

Full title: Tubuloids derived from human adult kidney and urine for personalized disease modeling

Authors: Schutgens, Frans; Rookmaaker, Maarten B; Margaritis, Thanasis; Rios, Anne; Ammerlaan, Carola; Jansen, Jitske; Gijzen, Linda; Vormann, Marianne; Vonk, Annelotte; Viveen, Marco; Yengej, Fjodor Yousef; Derakhshan, Sepide; de Winter-de Groot, Karin M; Artegiani, Benedetta; van Boxtel, Ruben; Cuppen, Edwin; Hendrickx, Antoni P A; van den Heuvel-Eibrink, Marry M; Heitzer, Ellen; Lanz, Henriette; Beekman, Jeffrey; Murk, Jean-Luc; Masereeuw, Rosalinde; Holstege, Frank; Drost, Jarno; Verhaar, Marianne C; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/378205

Thesis Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients

Jochems, Paulus G M; van Bergenhenegouwen, Jeroen; van Genderen, Anne Metje et al. · 2019 · Utrecht University · DOI

Full title: Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients

Authors: Jochems, Paulus G M; van Bergenhenegouwen, Jeroen; van Genderen, Anne Metje; Eis, Sophie T; Wilod Versprille, Livia J F; Wichers, Harry J; Jeurink, Prescilla V; Garssen, Johan; Masereeuw, Rosalinde

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/380332

Thesis Tradition, not science, is the basis of animal model selection in translational and applied research

Veening-Griffioen, Désirée H; Ferreira, Guilherme S; Boon, Wouter P C et al. · 2021 · Utrecht University · DOI

Full title: Tradition, not science, is the basis of animal model selection in translational and applied research

Authors: Veening-Griffioen, Désirée H; Ferreira, Guilherme S; Boon, Wouter P C; Gispen-de Wied, Christine C; Schellekens, Huub; Moors, Ellen H M; Van Meer, Peter J K

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/408501

Thesis Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine

Kramer, Nina; Pratscher, Barbara; Meneses, Andre M C et al. · 2020 · Utrecht University · DOI

Full title: Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine

Authors: Kramer, Nina; Pratscher, Barbara; Meneses, Andre M C; Tschulenk, Waltraud; Walter, Ingrid; Swoboda, Alexander; Kruitwagen, Hedwig S; Schneeberger, Kerstin; Penning, Louis C; Spee, Bart; Kieslinger, Matthias; Brandt, Sabine; Burgener, Iwan A

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/408080

Thesis Intestinal organoids for Cystic Fibrosis research

de Poel, E.; Lefferts, J. W.; Beekman, J. M. · 2020 · Utrecht University · DOI

Full title: Intestinal organoids for Cystic Fibrosis research

Authors: de Poel, E.; Lefferts, J. W.; Beekman, J. M.

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/394212

Thesis Kidney-based in vitro models for drug-induced toxicity testing

Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F et al. · 2019 · Utrecht University · DOI

Full title: Kidney-based in vitro models for drug-induced toxicity testing

Authors: Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F; Mihaila, Silvia M; Masereeuw, Rosalinde

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/394548

Thesis A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis et al. · 2020 · Utrecht University · DOI

Full title: A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Authors: Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis; Wybenga-Groot, Leanne E; Weiss, Konstantin; Rai, Ankit; Radulovich, Nikolina; Drecun, Luka; Vučković, Nika; Vučetić, Adriana; Wong, Victoria; Thériault, Brigitte; Pham, Nhu-An; Park, Jin H; Datti, Alessandro; Wang, Jenny; Pathmanathan, Shivanthy; Aboualizadeh, Farzaneh; Lyakisheva, Anna; Yao, Zhong; Wang, Yuhui; Joseph, Babu; Aman, Ahmed; Moran, Michael F; Prakesch, Michael; Poda, Gennady; Marcellus, Richard; Uehling, David; Samaržija, Miroslav; Jakopović, Marko; Tsao, Ming-Sound; Shepherd, Frances A; Sacher, Adrian; Leighl, Natasha; Akhmanova, Anna; Al-Awar, Rima; Zerial, Marino; Stagljar, Igor

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/410302

Thesis The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

van Berlo, Damiën; van de Steeg, Evita; Amirabadi, Hossein Eslami et al. · 2021 · Utrecht University · DOI

Full title: The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

Authors: van Berlo, Damiën; van de Steeg, Evita; Amirabadi, Hossein Eslami; Masereeuw, Rosalinde

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/412501

Thesis Levelling the Translational Gap for Animal to Human Efficacy Data

Ferreira, Guilherme S.; Veening-Griffioen, Désirée H.; Boon, Wouter P. C. et al. · 2020 · Utrecht University · DOI

Full title: Levelling the Translational Gap for Animal to Human Efficacy Data

Authors: Ferreira, Guilherme S.; Veening-Griffioen, Désirée H.; Boon, Wouter P. C.; Moors, Ellen H. M.; van Meer, Peter J. K.

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/408505

Thesis Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment

Tukker, Anke M; Wijnolts, Fiona M J; de Groot, Aart et al. · 2020 · Utrecht University · DOI

Full title: Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment

Authors: Tukker, Anke M; Wijnolts, Fiona M J; de Groot, Aart; Westerink, Remco H S

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/410154

Thesis Improving translation by identifying evidence for more human-relevant preclinical strategies

Ritskes-Hoitinga, Merel; Leenaars, Cathalijn; Beumer, Wouter et al. · 2020 · Utrecht University · DOI

Full title: Improving translation by identifying evidence for more human-relevant preclinical strategies

Authors: Ritskes-Hoitinga, Merel; Leenaars, Cathalijn; Beumer, Wouter; Roo, Tineke Coenen De; Stafleu, Frans; Meijboom, Franck L.B.

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/409049

Thesis Biomimetic models of the glomerulus

Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P. et al. · 2022 · Utrecht University · DOI

Full title: Biomimetic models of the glomerulus

Authors: Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P.; Cervantes, Ernesto; Li, Vanessa Y.; Bonventre, Joseph V.; Masereeuw, Rosalinde; Zhang, Yu Shrike

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/419293

Thesis Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies

Vormann, Marianne K.; Vriend, Jelle; Lanz, Henriëtte L. et al. · 2021 · Utrecht University · DOI

Full title: Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies

Authors: Vormann, Marianne K.; Vriend, Jelle; Lanz, Henriëtte L.; Gijzen, Linda; van den Heuvel, Angelique; Hutter, Simon; Joore, Jos; Trietsch, Sebastiaan J.; Stuut, Christiaan; Nieskens, Tom T.G.; Peters, Janny G.P.; Ramp, Daniela; Caj, Michaela; Russel, Frans G.M.; Jacobsen, Björn; Roth, Adrian; Lu, Shuyan; Polli, Joseph W.; Naidoo, Anita A.; Vulto, Paul; Masereeuw, Rosalinde; Wilmer, Martijn J.; Suter-Dick, Laura

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/411647

Thesis Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity

Gerber, Lora-Sophie; van Melis, Lennart V J; van Kleef, Regina G D M et al. · 2021 · Utrecht University · DOI

Full title: Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity

Authors: Gerber, Lora-Sophie; van Melis, Lennart V J; van Kleef, Regina G D M; de Groot, Aart; Westerink, Remco H S

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/413922

Thesis Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Bouwmeester, Manon C; Tao, Yu; Proença, Susana et al. · 2023 · Utrecht University · DOI

Full title: Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Authors: Bouwmeester, Manon C; Tao, Yu; Proença, Susana; van Steenbeek, Frank G; Samsom, Roos-Anne; Nijmeijer, Sandra M; Sinnige, Theo; van der Laan, Luc J W; Legler, Juliette; Schneeberger, Kerstin; Kramer, Nynke I; Spee, Bart

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426917

Thesis Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Wang, Zhenguo; Faria, João; van der Laan, Luc J.W. et al. · 2022 · Utrecht University · DOI

Full title: Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Authors: Wang, Zhenguo; Faria, João; van der Laan, Luc J.W.; Penning, Louis C.; Masereeuw, Rosalinde; Spee, Bart

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/424214

Thesis A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells

Bai, Jing; Fu, Haojie; Bazinet, Lauren et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells

Authors: Bai, Jing; Fu, Haojie; Bazinet, Lauren; Birsner, Amy E.; D'Amato, Robert J.

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/125467

Thesis Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Schepers, Arnout G; Shan, Jing; Cox, Andrew G et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Authors: Schepers, Arnout G; Shan, Jing; Cox, Andrew G; Huang, Ada; Evans, Helen; Walesky, Chad; Fleming, Heather E; Goessling, Wolfram; Bhatia, Sangeeta N

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/142801

Thesis Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes

Michailidis, Eleftherios; Vercauteren, Koen; Mancio-Silva, Liliana et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes

Authors: Michailidis, Eleftherios; Vercauteren, Koen; Mancio-Silva, Liliana; Andrus, Linda; Jahan, Cyprien; Ricardo-Lax, Inna; Zou, Chenhui; Kabbani, Mohammad; Park, Paul; Quirk, Corrine; Pyrgaki, Christina; Razooky, Brandon; Verhoye, Lieven; Zoluthkin, Irene; Lu, Wei-Yu; Forbes, Stuart J; Chiriboga, Luis; Theise, Neil D; Herzog, Roland W; Suemizu, Hiroshi; Schneider, William M; Shlomai, Amir; Meuleman, Philip; Bhatia, Sangeeta N; Rice, Charles M; de Jong, Ype P

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/136265

Thesis Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers

Mancio Silva, Liliana; Fleming, Heather; Miller, Alex B et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers

Authors: Mancio Silva, Liliana; Fleming, Heather; Miller, Alex B; Milstein, Stuart; Liebow, Abigail; Haslett, Patrick; Sepp-Lorenzino, Laura; Bhatia, Sangeeta N

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/128861

Thesis Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

Bein, Amir; Kim, Seongmin; Goyal, Girija et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

Authors: Bein, Amir; Kim, Seongmin; Goyal, Girija; Cao, Wuji; Fadel, Cicely; Naziripour, Arash; Sharma, Sanjay; Swenor, Ben; LoGrande, Nina; Nurani, Atiq; Miao, Vincent N; Navia, Andrew W; Ziegler, Carly GK; Montañes, José Ordovas; Prabhala, Pranav; Kim, Min Sun; Prantil-Baun, Rachelle; Rodas, Melissa; Jiang, Amanda; O’Sullivan, Lucy; Tillya, Gladness; Shalek, Alex K; Ingber, Donald E

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/141283

Thesis A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors

Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors

Authors: Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M.; Sheridan, Steven D.; Tsai, Li-Huei; Haggarty, Stephen J.

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/92893

Thesis A low-cost 3D printed microfluidic bioreactor and imaging chamber for live-organoid imaging

Khan, Ikram; Prabhakar, Anil; Delepine, Chloe et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A low-cost 3D printed microfluidic bioreactor and imaging chamber for live-organoid imaging

Authors: Khan, Ikram; Prabhakar, Anil; Delepine, Chloe; Tsang, Hayley; Pham, Vincent; Sur, Mriganka

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/142062

Thesis A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

March-Riera, Sandra; Ng, Shengyong; Velmurugan, Soundarapandian et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

Authors: March-Riera, Sandra; Ng, Shengyong; Velmurugan, Soundarapandian; Galstian, Ani; Shan, Jing; Logan, David J.; Carpenter, Anne E.; Thomas, David; Sim, B. Kim Lee; Mota, Maria M.; Hoffman, Stephen L.

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/86118

Thesis Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Tong, Zhixiang; Martyn, Keir; Yang, Andy et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Authors: Tong, Zhixiang; Martyn, Keir; Yang, Andy; Yin, Xiaolei; Mead, Benjamin E.; Joshi, Nitin; Sherman, Nicholas E.; Langer, Robert S.; Karp, Jeffrey M.

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/134688.2

Thesis Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Saha, Krishanu; Jaenisch, Rudolf · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Authors: Saha, Krishanu; Jaenisch, Rudolf

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96182

Thesis Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

Xu, Jinghai J.; Hendriks, Bart S.; Cosgrove, Benjamin D. et al. · 2011 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

Authors: Xu, Jinghai J.; Hendriks, Bart S.; Cosgrove, Benjamin D.; King, Bracken Matheny; Hasan, Maya A.; Alexopoulos, Leonidas G.; Farazi, Paraskevi A.; Sorger, Peter K.; Tidor, Bruce; Griffith, Linda G.; Lauffenburger, Douglas A.

Year: 2011

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/67046

Thesis Identification of small molecules for human hepatocyte expansion and iPS differentiation

Shan, Jing; Ross, Nathan T.; Logan, David J. et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Identification of small molecules for human hepatocyte expansion and iPS differentiation

Authors: Shan, Jing; Ross, Nathan T.; Logan, David J.; Thomas, David; Duncan, Stephen A.; North, Trista E.; Goessling, Wolfram; Carpenter, Anne E.; Schwartz, Robert E.; Bhatia, Sangeeta N

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/86114

Thesis In vitro models for liver toxicity testing

Soldatow, Valerie Y.; LeCluyse, Edward L.; Griffith, Linda G. et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: In vitro models for liver toxicity testing

Authors: Soldatow, Valerie Y.; LeCluyse, Edward L.; Griffith, Linda G.; Rusyn, Ivan

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/88931

Thesis Regenerative Medicine: Learning from Past Examples

Couto, Daniela S.; Perez-Breva, Luis; Cooney, Charles L. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Regenerative Medicine: Learning from Past Examples

Authors: Couto, Daniela S.; Perez-Breva, Luis; Cooney, Charles L.

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/72661

Thesis Approaches to in vitro tissue regeneration with application for human disease modeling and drug development

Young, Carissa L.; Lauffenburger, Douglas A.; Griffith, Linda G. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Approaches to in vitro tissue regeneration with application for human disease modeling and drug development

Authors: Young, Carissa L.; Lauffenburger, Douglas A.; Griffith, Linda G.; Borenstein, Jeffrey T.; Ebrahimkhani, Mohammad Reza

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/99479

Thesis Generation of a canine enteroid-derived monolayer model to study gut barrier structure and function

Lopez Cervantes, Veronica Martina · 2022 · University of California, Davis · DOI

Full title: Generation of a canine enteroid-derived monolayer model to study gut barrier structure and function

Authors: Lopez Cervantes, Veronica Martina

Year: 2022

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/06f525x4

Thesis Commercialization of Transiently Transfected Cell Lines for High Throughput Drug Screening and Profiling Applications

Mehta, Kalpita Deepak · 2010 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Commercialization of Transiently Transfected Cell Lines for High Throughput Drug Screening and Profiling Applications

Authors: Mehta, Kalpita Deepak

Year: 2010

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1269628794

Thesis MULTICEULLULAR TUMOR HEMI-SPHEROID: A NOVEL IN VITRO 3D MODEL PLATFORM FOR ACCELERATED DRUG DEVELOPMENT

Kim, Kihwan · 2017 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: MULTICEULLULAR TUMOR HEMI-SPHEROID: A NOVEL IN VITRO 3D MODEL PLATFORM FOR ACCELERATED DRUG DEVELOPMENT

Authors: Kim, Kihwan

Year: 2017

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1481900120946458

Thesis 3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development

Yen, Terence, Yen · 2017 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: 3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development

Authors: Yen, Terence, Yen

Year: 2017

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367

Thesis Tools for translational drug development: Mass cytometry paired cell culture, novel mouse models, and identifying existing model pitfalls

Johnson, Mariah L. · 2021 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Tools for translational drug development: Mass cytometry paired cell culture, novel mouse models, and identifying existing model pitfalls

Authors: Johnson, Mariah L.

Year: 2021

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1638519884135162

Thesis Development and Optimization of a Cell Derived Matrix Assay using Primary Lung Fibroblasts

Adams, Morgan · 2024 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Development and Optimization of a Cell Derived Matrix Assay using Primary Lung Fibroblasts

Authors: Adams, Morgan

Year: 2024

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=ucin172139732999051

Thesis Commercialization of Pre-Clinical Cardiac Safety Using Stem Cell Derived Human Cardiomyocytes

Sethia, Vinay K. · 2011 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Commercialization of Pre-Clinical Cardiac Safety Using Stem Cell Derived Human Cardiomyocytes

Authors: Sethia, Vinay K.

Year: 2011

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1307731193

Thesis Human liver in vitro models for evaluation of drug metabolism and disposition

Malin Darnell (18638197) · 2012 · Karolinska Institutet · DOI

Full title: Human liver in vitro models for evaluation of drug metabolism and disposition

Authors: Malin Darnell (18638197)

Year: 2012

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26921098

Thesis Novel culture systems to model testicular function and organization

Joao Pedro Lopes (18677530) · 2018 · Karolinska Institutet · DOI

Full title: Novel culture systems to model testicular function and organization

Authors: Joao Pedro Lopes (18677530)

Year: 2018

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26906248

Thesis Bioengineered human colon organoids with in vivo-like cellular complexity and function

Mitrofanova, Olga; Nikolaev, Mikhail; Xu, Quan et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineered human colon organoids with in vivo-like cellular complexity and function

Authors: Mitrofanova, Olga; Nikolaev, Mikhail; Xu, Quan; Broguiere, Nicolas; Cubela, Irineja; Camp, J. Gray; Bscheider, Michael; Lutolf, Matthias P.

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/243339

Thesis Microwell devices for single-cell analyses

Lindström, Sara · 2009 · KTH Royal Institute of Technology · DOI

Full title: Microwell devices for single-cell analyses

Authors: Lindström, Sara

Year: 2009

Venue: KTH Royal Institute of Technology

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11665

Thesis Exploration of novel hepatic In-vitro systems for drug metabolism and pharmacokinetic studies

Lena Preiss (18664720) · 2023 · Karolinska Institutet · DOI

Full title: Exploration of novel hepatic In-vitro systems for drug metabolism and pharmacokinetic studies

Authors: Lena Preiss (18664720)

Year: 2023

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/26924149

Thesis Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

El Abdellaoui Soussi, Fadoua; Piraino, Francesco; Scholefield, Janine et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

Authors: El Abdellaoui Soussi, Fadoua; Piraino, Francesco; Scholefield, Janine; Hoehnel-Ka, Sylke; Kasendra, Magdalena

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250663

Thesis Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program

Laurent, Alexis; Scaletta, Corinne; Abdel-Sayed, Philippe et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program

Authors: Laurent, Alexis; Scaletta, Corinne; Abdel-Sayed, Philippe; Michetti, Murielle; de Buys Roessingh, Anthony; Raffoul, Wassim; Hirt-Burri, Nathalie; Applegate, Lee Ann

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/253986

Thesis Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes

Unzu, Carmen; Planet, Evarist; Brandenberg, Nathalie et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes

Authors: Unzu, Carmen; Planet, Evarist; Brandenberg, Nathalie; Fusil, Floriane; Cassano, Marco; Perez‐Vargas, Jimena; Friedli, Marc; Cosset, François‐Loïc; Lutolf, Matthias P.; Wildhaber, Barbara E; Trono, Didier

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/154489

Thesis Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells

Drawnel, Faye M.; Boccardo, Stefano; Prummer, Michael et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells

Authors: Drawnel, Faye M.; Boccardo, Stefano; Prummer, Michael; Delobel, Frederic; Graff, Alexandra; Weber, Michael; Gerard, Regine; Badi, Laura; Kam-Thong, Tony; Bu, Lei; Jiang, Xin; Hoflack, Jean-Christophe; Kiialainen, Anna; Jeworutzki, Elena; Aoyama, Natsuyo; Carlson, Coby; Burcin, Mark; Gromo, Gianni; Boehringer, Markus; Stahlberg, Henning; Hall, Benjamin J.; Magnone, Maria Chiara; Kolaja, Kyle; Chien, Kenneth R.; Bailly, Jacques; Iacone, Roberto

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/165344

Thesis Progress and potential in organoid research

Rossi, Giuliana; Manfrin, Andrea; Lutolf, Matthias P. · 2018 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Progress and potential in organoid research

Authors: Rossi, Giuliana; Manfrin, Andrea; Lutolf, Matthias P.

Year: 2018

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/151819

Thesis Development Strategies for Animal Medical Therapeutics

Morrison, Alexander H; Mason, Nicola J; Paterson, Yvonne · 2023 · University of Pennsylvania · DOI

Full title: Development Strategies for Animal Medical Therapeutics

Authors: Morrison, Alexander H; Mason, Nicola J; Paterson, Yvonne

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/1182

Thesis Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration

Shin, Min-Kyoung; Bang, Jin Seok; Lee, Jeoung Eun et al. · 2022 · Okinawa Institute of Science and Technology (OIST) · DOI

Full title: Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration

Authors: Shin, Min-Kyoung; Bang, Jin Seok; Lee, Jeoung Eun; Tran, Hoang-Dai; Park, Genehong; Lee, Dong Ryul; Jo, Junghyun

Year: 2022

Venue: Okinawa Institute of Science and Technology (OIST)

DOI: https://oist.repo.nii.ac.jp/record/2750/files/Shin-2022-Generation of Skeletal Muscle Organo.pdf

Thesis Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

Csukovich, Georg (University of Veterinary Medicine, Vienna); Kramer, Nina (University of Veterinary Medicine, Vienna); Pratscher, Barbara (University of Veterinary Medicine, Vienna) et al. · 2023 · University of Veterinary Medicine Vienna (Vetmeduni Vienna) · DOI

Full title: Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

Authors: Csukovich, Georg (University of Veterinary Medicine, Vienna); Kramer, Nina (University of Veterinary Medicine, Vienna); Pratscher, Barbara (University of Veterinary Medicine, Vienna); Gotic, Ivana (The Antibody Lab GmbH); Freund, Patricia (University of Veterinary Medicine, Vienna); Hahn, Rainer (University of Natural Resources and Life Sciences Vienna); Himmler, Gottfried (The Antibody Lab GmbH); Brandt, Sabine (University of Veterinary Medicine, Vienna); Burgener, Iwan Anton (University of Veterinary Medicine, Vienna)

Year: 2023

Venue: University of Veterinary Medicine Vienna (Vetmeduni Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:1377

Thesis The World of Organoids: Gastrointestinal Disease Modelling in the Age of 3R and One Health with Specific Relevance to Dogs and Cats

Csukovich, Georg (University of Veterinary Medicine Vienna); Burgener, Iwan Anton (University of Veterinary Medicine Vienna); Pratscher, Barbara (University of Veterinary Medicine Vienna) · 2022 · University of Veterinary Medicine Vienna (Vetmeduni Vienna) · DOI

Full title: The World of Organoids: Gastrointestinal Disease Modelling in the Age of 3R and One Health with Specific Relevance to Dogs and Cats

Authors: Csukovich, Georg (University of Veterinary Medicine Vienna); Burgener, Iwan Anton (University of Veterinary Medicine Vienna); Pratscher, Barbara (University of Veterinary Medicine Vienna)

Year: 2022

Venue: University of Veterinary Medicine Vienna (Vetmeduni Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:2082

Thesis Modeling reproductive and pregnancy-associated tissues using organ-on-chip platforms: challenges, limitations, and the high throughput data frontier

Truong, Nina; Zahra, Abir; Lintao, Ryan C. V. et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Modeling reproductive and pregnancy-associated tissues using organ-on-chip platforms: challenges, limitations, and the high throughput data frontier

Authors: Truong, Nina; Zahra, Abir; Lintao, Ryan C. V.; Chauhan, Rahul; Bento, Giovana Fernanda [UNESP]; Vidal Jr, Manuel; Kim, Sungjin; Lam, Po Yi; Conrads, Thomas; Conrads, Kelly; Han, Arum; Menon, Ramkumar; Richardson, Lauren S.

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.3389/fbioe.2025.1568389

Thesis A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip

Moro, Lincoln Gozzi; Guarnier, Lucas Pires; Azevedo, Maurício Fogaça et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip

Authors: Moro, Lincoln Gozzi; Guarnier, Lucas Pires; Azevedo, Maurício Fogaça; Fracasso, Julia Amanda Rodrigues [UNESP]; Lucio, Marco Aurélio; Castro, Mateus Vidigal de; Dias, Marlon Lemos; Lívero, Francislaine Aparecida dos Reis; Ribeiro-Paes, João Tadeu [UNESP]

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.3390/cells13242068

Thesis High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

Norkin, Maxim; Ordóñez-Morán, Paloma; Huelsken, Joerg · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

Authors: Norkin, Maxim; Ordóñez-Morán, Paloma; Huelsken, Joerg

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/177705

Thesis Mechano-modulatory synthetic niches for liver organoid derivation

Sorrentino, Giovanni; Rezakhani, Saba; Yildiz, Ece et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mechano-modulatory synthetic niches for liver organoid derivation

Authors: Sorrentino, Giovanni; Rezakhani, Saba; Yildiz, Ece; Nuciforo, Sandro; Heim, Markus H.; Lutolf, Matthias P.; Schoonjans, Kristina

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/170291

Thesis Live mammalian cell arrays

Woodruff, Kristina Pan; Fidalgo, Luis Miguel; Gobaa, Samy et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Live mammalian cell arrays

Authors: Woodruff, Kristina Pan; Fidalgo, Luis Miguel; Gobaa, Samy; Lutolf, Matthias; Maerkl, Sebastian

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/92240

Thesis Drug discovery through stem cell-based organoid models

Ranga, Adrian; Gjorevski, Nikolche; Lütolf, Matthias · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Drug discovery through stem cell-based organoid models

Authors: Ranga, Adrian; Gjorevski, Nikolche; Lütolf, Matthias

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/101815

Thesis DEVELOPMENT OF A HUMAN iPSC DERIVED MICROGLIA ASSAY FOR EVALUATION OF TARGET DEPENDENT ACTIVATION AND PHARMACOLOGICAL INHIBITION

Biji, Christy · 2023 · Johns Hopkins University · DOI

Full title: DEVELOPMENT OF A HUMAN iPSC DERIVED MICROGLIA ASSAY FOR EVALUATION OF TARGET DEPENDENT ACTIVATION AND PHARMACOLOGICAL INHIBITION

Authors: Biji, Christy

Year: 2023

Venue: Johns Hopkins University

DOI: http://jhir.library.jhu.edu/handle/1774.2/68748

Thesis Hurdles in basic science translation

Perry, CJ; Lawrence, AJ · 2020 · University of Melbourne · DOI

Full title: Hurdles in basic science translation

Authors: Perry, CJ; Lawrence, AJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/256646

Thesis A HUMAN BRAIN MICROPHYSIOLOGICAL SYSTEM FOR THE STUDY OF PARKINSON’S DISEASE

Stubenhaus, Bradford Michael · 2018 · Johns Hopkins University · DOI

Full title: A HUMAN BRAIN MICROPHYSIOLOGICAL SYSTEM FOR THE STUDY OF PARKINSON’S DISEASE

Authors: Stubenhaus, Bradford Michael

Year: 2018

Venue: Johns Hopkins University

DOI: http://jhir.library.jhu.edu/handle/1774.2/58691

Thesis Trends in bone metastasis modeling

Laranga, R; Duchi, S; Ibrahim, T et al. · 2020 · University of Melbourne · DOI

Full title: Trends in bone metastasis modeling

Authors: Laranga, R; Duchi, S; Ibrahim, T; Guerrieri, AN; Donati, DM; Lucarelli, E

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/244361

Thesis Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Huang, JX; Kaeslin, G; Ranall, MV et al. · 2021 · University of Melbourne · DOI

Full title: Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Authors: Huang, JX; Kaeslin, G; Ranall, MV; Blaskovich, MA; Becker, B; Butler, MS; Little, MH; Lash, LH; Cooper, MA

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/261473

Thesis Application of Urine-Derived Stem Cells to Cellular Modeling in Neuromuscular and Neurodegenerative Diseases

Sato, M; Takizawa, H; Nakamura, A et al. · 2020 · University of Melbourne · DOI

Full title: Application of Urine-Derived Stem Cells to Cellular Modeling in Neuromuscular and Neurodegenerative Diseases

Authors: Sato, M; Takizawa, H; Nakamura, A; Turner, BJ; Shabanpoor, F; Aoki, Y

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/247275

Thesis 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

Hale, LJ; Howden, SE; Phipson, B et al. · 2020 · University of Melbourne · DOI

Full title: 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

Authors: Hale, LJ; Howden, SE; Phipson, B; Lonsdale, A; Er, PX; Ghobrial, I; Hosawi, S; Wilson, S; Lawlor, KT; Khan, S; Oshlack, A; Quinlan, C; Lennon, R; Little, MH

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/253542

Thesis Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Krishnan, R; Park, JA; Seow, CY et al. · 2016 · University of Melbourne · DOI

Full title: Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Authors: Krishnan, R; Park, JA; Seow, CY; Lee, PVS; Stewart, AG

Year: 2016

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/116482

Thesis High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

Choo, N; Ramm, S; Luu, J et al. · 2021 · University of Melbourne · DOI

Full title: High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

Authors: Choo, N; Ramm, S; Luu, J; Winter, JM; Selth, LA; Dwyer, AR; Frydenberg, M; Grummet, J; Sandhu, S; Hickey, TE; Tilley, WD; Taylor, RA; Risbridger, GP; Lawrence, MG; Simpson, KJ

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/281073

Thesis Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease

Quah, PS; Tran, BM; Corbin, VDA et al. · 2023 · University of Melbourne · DOI

Full title: Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease

Authors: Quah, PS; Tran, BM; Corbin, VDA; Chang, JJ-Y; Wong, CY; Diaz-Méndez, A; Hartley, CA; Zeng, W; Hanssen, E; Trifunovic, Z; Reading, PC; Jackson, DC; Vincan, E; Coin, LJM; Deliyannis, G

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/339334

Thesis Unprecedented potential for neural drug discovery based on self-organizing hiPSC platforms

Cota-Coronado, A; Durnall, JC; Díaz, NF et al. · 2020 · University of Melbourne · DOI

Full title: Unprecedented potential for neural drug discovery based on self-organizing hiPSC platforms

Authors: Cota-Coronado, A; Durnall, JC; Díaz, NF; Thompson, LH; Díaz-Martínez, NE

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/245942

Thesis Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Ergir, E; Oliver-De La Cruz, J; Fernandes, S et al. · 2023 · University of Melbourne · DOI

Full title: Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Authors: Ergir, E; Oliver-De La Cruz, J; Fernandes, S; Cassani, M; Niro, F; Pereira-Sousa, D; Vrbský, J; Vinarský, V; Perestrelo, AR; Debellis, D; Vadovičová, N; Uldrijan, S; Cavalieri, F; Pagliari, S; Redl, H; Ertl, P; Forte, G

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/335236

Thesis Investigating the feasibility and ethical implications of phenotypic screening using stem cell-derived tissue models to detect and manage disease

Harris, AR; Walker, MJ; Gilbert, F et al. · 2022 · University of Melbourne · DOI

Full title: Investigating the feasibility and ethical implications of phenotypic screening using stem cell-derived tissue models to detect and manage disease

Authors: Harris, AR; Walker, MJ; Gilbert, F; McGivern, P

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316082

Thesis Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Hirokawa, Y; Clarke, J; Palmieri, M et al. · 2021 · University of Melbourne · DOI

Full title: Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Authors: Hirokawa, Y; Clarke, J; Palmieri, M; Tan, T; Mouradov, D; Li, S; Lin, C; Li, F; Luo, H; Wu, K; Faux, M; Tan, CW; Lee, M; Gard, G; Gibbs, P; Burgess, AW; Sieber, OM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/289714

Thesis Perspectives on phenotypic screening-Screen Design and Assay Technology Special Interest Group

Pak, C; Simpson, KJ; Weston, AD et al. · 2024 · University of Melbourne · DOI

Full title: Perspectives on phenotypic screening-Screen Design and Assay Technology Special Interest Group

Authors: Pak, C; Simpson, KJ; Weston, AD; Cvijic, ME; Evans, K; Napper, AD

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/351817

Thesis Airway models in a pandemic: Suitability of models in modeling SARS-CoV-2

Teo, A; Chua, CLL; Chan, LLY · 2022 · University of Melbourne · DOI

Full title: Airway models in a pandemic: Suitability of models in modeling SARS-CoV-2

Authors: Teo, A; Chua, CLL; Chan, LLY

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/307163

Thesis Human Retinal Organoid Model of Ocular Toxoplasmosis

Ashander, LM; Lidgerwood, GE; Lumsden, AL et al. · 2025 · University of Melbourne · DOI

Full title: Human Retinal Organoid Model of Ocular Toxoplasmosis

Authors: Ashander, LM; Lidgerwood, GE; Lumsden, AL; Furtado, JM; Pébay, A; Smith, JR

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360229

Thesis AAV capsid bioengineering in primary human retina models

Westhaus, A; Eamegdool, SS; Fernando, M et al. · 2024 · University of Melbourne · DOI

Full title: AAV capsid bioengineering in primary human retina models

Authors: Westhaus, A; Eamegdool, SS; Fernando, M; Fuller-Carter, P; Brunet, AA; Miller, AL; Rashwan, R; Knight, M; Daniszewski, M; Lidgerwood, GE; Pébay, A; Hewitt, A; Santilli, G; Thrasher, AJ; Carvalho, LS; Gonzalez-Cordero, A; Jamieson, RV; Lisowski, L

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/344430

Thesis A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases

Brunet, AA; James, RE; Swanson, P et al. · 2025 · University of Melbourne · DOI

Full title: A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases

Authors: Brunet, AA; James, RE; Swanson, P; Carvalho, LS

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360367

Thesis Complementarity and integration of animal and in vitro non-animal pre-clinical model systems� an Australian perspective

· 2025 · University of Melbourne · DOI

Full title: Complementarity and integration of animal and in vitro non-animal pre-clinical model systems� an Australian perspective

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/362325

Thesis High-Throughput 3-D Cellular Assays Using Destabilized Green Fluorescence Protein

Fraley, Brian · 2010 · The Ohio State University · DOI

Full title: High-Throughput 3-D Cellular Assays Using Destabilized Green Fluorescence Protein

Authors: Fraley, Brian

Year: 2010

Venue: The Ohio State University

DOI: http://hdl.handle.net/1811/44750

Thesis Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Heslop, JA; Rowe, C; Walsh, J et al. · 2017 · University of Liverpool · DOI

Full title: Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Authors: Heslop, JA; Rowe, C; Walsh, J; Sison-Young, R; Jenkins, R; Kamalian, L; Kia, R; Hay, D; Jones, RP; Malik, HZ; Fenwick, S; Chadwick, AE; Mills, J; Kitteringham, NR; Goldring, CEP; Kevin Park, B

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3003185/1/Heslop%20hepatocyte%20differentiation.pdf

Thesis Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

Ravenscroft, Stephanie M; Pointon, Amy; Williams, Awel W et al. · 2016 · University of Liverpool · DOI

Full title: Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

Authors: Ravenscroft, Stephanie M; Pointon, Amy; Williams, Awel W; Cross, Michael J; Sidaway, James E

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3002266/1/Cardiac%20Non-myocyte%20Cells%20Show%20Enhanced%20Pharmacological%20Function%20Suggestive%20of%20Contractile%20Maturity%20in%20Stem%20Cell%20Derived%20Cardiomyocyte%20Microtissues.pdf

Thesis Donor‐Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells

Heslop, J; Kia, R; Pridgeon, C et al. · 2017 · University of Liverpool · DOI

Full title: Donor‐Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells

Authors: Heslop, J; Kia, R; Pridgeon, C; Sison-Young, R; Liloglou, T; Elmasry, M; Fenwick, S; Mills, JS; Kitteringham, N; Goldring, C; Park, BK

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3004957/1/R2%20proof%20of%20SCTM%20submission.pdf

Thesis A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Sison-Young, RL; Lauschke, VM; Johann, E et al. · 2017 · University of Liverpool · DOI

Full title: A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Authors: Sison-Young, RL; Lauschke, VM; Johann, E; Alexandre, E; Antherieu, S; Aerts, H; Gerets, HHJ; Labbe, G; Hoët, D; Dorau, M; Schofield, CA; Lovatt, CA; Holder, JC; Stahl, SH; Richert, L; Kitteringham, NR; Jones, RP; Elmasry, M; Weaver, RJ; Hewitt, PG; Ingelman-Sundberg, M; Goldring, CE; Park, BK

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3006887/2/A%20multicenter%20assessment%20of%20single-cell%20models%20aligned%20to%20standard%20measures%20of%20cell%20health%20for%20prediction%20of%20acute%20hepatotoxicity.pdf

Thesis Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment

Kyffin, Jonathan A; Sharma, Parveen; Leedale, Joseph et al. · 2018 · University of Liverpool · DOI

Full title: Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment

Authors: Kyffin, Jonathan A; Sharma, Parveen; Leedale, Joseph; Colley, Helen E; Murdoch, Craig; Mistry, Pratibha; Webb, Steven D

Year: 2018

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3020420/1/Kyfinn%20et%20al%202018_revised.pdf

Thesis Stem cell models as an in vitro model for predictive toxicology

Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A et al. · 2019 · University of Liverpool · DOI

Full title: Stem cell models as an in vitro model for predictive toxicology

Authors: Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A; Sharma, Parveen; Park, B Kevin; Goldring, Chris EP

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3038014/1/8533_1_art_file_303843_pffps1.pdf

Thesis Developing a 3D intestinal epithelium model for livestock species

Derricott, H; Luu, L; Fong, WY et al. · 2019 · University of Liverpool · DOI

Full title: Developing a 3D intestinal epithelium model for livestock species

Authors: Derricott, H; Luu, L; Fong, WY; Hartley, CS; Johnston, LJ; Armstrong, SD; Randle, N; Duckworth, CA; Campbell, BJ; Wastling, JM; Coombes, JL

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3027174/1/Derricott2018_Article_DevelopingA3DIntestinalEpithel.pdf

Thesis Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, Catherine C; Hendriks, Delilah FG; Moro, Sabrina ML et al. · 2016 · University of Liverpool · DOI

Full title: Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Authors: Bell, Catherine C; Hendriks, Delilah FG; Moro, Sabrina ML; Ellis, Ewa; Walsh, Joanne; Renblom, Anna; Fredriksson Puigvert, Lisa; Dankers, Anita CA; Jacobs, Frank; Snoeys, Jan; Sison-Young, Rowena L; Jenkins, Rosalind E; Nordling, Åsa; Mkrtchian, Souren; Park, B Kevin; Kitteringham, Neil R; Goldring, Christopher EP; Lauschke, Volker M; Ingelman-Sundberg, Magnus

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3006890/2/Characterization%20of%20primary%20human%20hepatocyte%20spheroids%20as%20a%20model%20system%20for%20drug-induced%20liver%20injury%2C%20liver%20function%20and%20disease.pdf

Thesis Multiscale modelling of drug transport and metabolism in liver spheroids

Leedale, JA; Kyffin, Jonathan; Harding, Amy et al. · 2020 · University of Liverpool · DOI

Full title: Multiscale modelling of drug transport and metabolism in liver spheroids

Authors: Leedale, JA; Kyffin, Jonathan; Harding, Amy; Colley, Helen; Murdoch, Craig; Sharma, Parveen; Williams, Dominic; Webb, Steven; Bearon, Rachel

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3077573/1/Leedale_IF_2019.pdf

Thesis Stem cell models as an in vitro model for predictive toxicology.

Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A et al. · 2019 · University of Liverpool · DOI

Full title: Stem cell models as an in vitro model for predictive toxicology.

Authors: Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A; Sharma, Parveen; Park, B Kevin; Goldring, Chris EP

Year: 2019

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3037014/1/8533_1_art_file_303843_pffps1.pdf

Thesis A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro

Eyre, Jessica J; Williams, Rachel L; Levis, Hannah J · 2020 · University of Liverpool · DOI

Full title: A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro

Authors: Eyre, Jessica J; Williams, Rachel L; Levis, Hannah J

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3104213/1/Elements%20-Unmarked%20Manuscript-JJ%20Eyre%2CRL%20Williams%2CHJ%20Levis%20.pdf

Thesis Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

Cox, Christopher R; Lynch, Stephen; Goldring, Christopher et al. · 2020 · University of Liverpool · DOI

Full title: Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

Authors: Cox, Christopher R; Lynch, Stephen; Goldring, Christopher; Sharma, Parveen

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3112054/1/Cox%20et%20al.pdf

Thesis Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters

Kilfoil, Peter; Feng, Shuyun Lily; Bassyouni, Asser et al. · 2021 · University of Liverpool · DOI

Full title: Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters

Authors: Kilfoil, Peter; Feng, Shuyun Lily; Bassyouni, Asser; Lee, Tiffany; Leishman, Derek; Li, Dingzhou; MacEwan, David J; Sharma, Parveen; Watt, Eric D; Jenkinson, Stephen

Year: 2021

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3141575/1/Kilfoil_Stem%20Cell%20Manuscript_Final%20Draft.pdf

Thesis From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

Malakpour Permlid, Atena · 2020 · Lund University (LUP) · DOI

Full title: From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

Authors: Malakpour Permlid, Atena

Year: 2020

Venue: Lund University (LUP)

DOI: https://lup.lub.lu.se/record/25a3ea4a-d8ec-49d2-bdb7-d2a74473dc17

Thesis Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19

Assmus, Frauke; Driouich, Jean-Selim; Abdelnabi, Rana et al. · 2022 · University of Liverpool · DOI

Full title: Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19

Authors: Assmus, Frauke; Driouich, Jean-Selim; Abdelnabi, Rana; Vangeel, Laura; Touret, Franck; Adehin, Ayorinde; Chotsiri, Palang; Cochin, Maxime; Foo, Caroline S; Jochmans, Dirk; Kim, Seungtaek; Luciani, Lea; Moureau, Gregory; Park, Soonju; Petit, Paul-Remi; Shum, David; Wattanakul, Thanaporn; Weynand, Birgit; Fraisse, Laurent; Ioset, Jean-Robert; Mowbray, Charles E; Owen, Andrew; Hoglund, Richard M; Tarning, Joel; de Lamballerie, Xavier; Nougairede, Antoine; Neyts, Johan; Sjo, Peter; Escudie, Fanny; Scandale, Ivan; Chatelain, Eric

Year: 2022

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3165843/1/Need%20for%20a%20Standardized%20Translational%20Drug%20Development%20Platform%20Lessons%20Learned%20from%20the%20Repurposing%20of%20Drugs%20for%20COVID-19.pdf

Thesis Recording from human gut tissue: a major step towards more efficient drug development?

Schemann, Michael · 2011 · Technical University of Munich (TUM) · DOI

Full title: Recording from human gut tissue: a major step towards more efficient drug development?

Authors: Schemann, Michael

Year: 2011

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1316500

Thesis Development of an in vitro mechanistic toxicity screening model using cultured hepatocytes

· 2013 · University of Pretoria · DOI

Full title: Development of an in vitro mechanistic toxicity screening model using cultured hepatocytes

Year: 2013

Venue: University of Pretoria

DOI: http://hdl.handle.net/2263/24162

Thesis New methodologies for old problems: Tridimensional gastrointestinal organoids and guts-on-a-chip

Sakalem, Marna Eliana [UNESP]; Ribeiro-Paes, João Tadeu [UNESP] · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: New methodologies for old problems: Tridimensional gastrointestinal organoids and guts-on-a-chip

Authors: Sakalem, Marna Eliana [UNESP]; Ribeiro-Paes, João Tadeu [UNESP]

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1016/j.jcol.2017.10.002

Thesis Intensive care for human hearts in pluripotent stem cell models

Golforoush, Pelin; Schneider, Michael · 2020 · Imperial College London · DOI

Full title: Intensive care for human hearts in pluripotent stem cell models

Authors: Golforoush, Pelin; Schneider, Michael

Year: 2020

Venue: Imperial College London

DOI: https://www.nature.com/articles/s41536-020-0090-7

Thesis Microsystems manufacturing technologies for pharmaceutical toxicity testing

Macdonald, Niall Patrick · 2013 · University of Glasgow · DOI

Full title: Microsystems manufacturing technologies for pharmaceutical toxicity testing

Authors: Macdonald, Niall Patrick

Year: 2013

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/5070/1/Macdonald.pdf

Thesis Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

Conway, JRW; https://orcid.org/0000-0003-3787-277X; Vennin, C et al. · 2017 · UNSW Sydney · DOI

Full title: Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

Authors: Conway, JRW ; https://orcid.org/0000-0003-3787-277X; Vennin, C; Cazet, AS ; https://orcid.org/0000-0001-7075-8448; Herrmann, D ; https://orcid.org/0000-0002-9514-7501; Murphy, KJ ; https://orcid.org/0000-0002-3234-3812; Warren, SC ; https://orcid.org/0000-0002-5253-7147; Wullkopf, L; Boulghourjian, A; Zaratzian, A; Da Silva, AM; Pajic, M ; https://orcid.org/0000-0002-3871-3829; Morton, JP; Cox, TR ; https://orcid.org/0000-0001-9294-1745; Timpson, P

Year: 2017

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_49860

Thesis Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.

Sampaziotis, Fotios; de Brito, Miguel Cardoso; Madrigal, Pedro et al. · 2015 · University of Cambridge · DOI

Full title: Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.

Authors: Sampaziotis, Fotios; de Brito, Miguel Cardoso; Madrigal, Pedro; Bertero, Alessandro; Saeb-Parsy, Kourosh; Soares, Filipa AC; Schrumpf, Elisabeth; Melum, Espen; Karlsen, Tom H; Bradley, J Andrew; Gelson, William Th; Davies, Susan; Baker, Alastair; Kaser, Arthur; Alexander, Graeme J; Hannan, Nicholas RF; Vallier, Ludovic

Year: 2015

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/248631

Thesis Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint

Liu, Y; Gill, E; Shery Huang, YY · 2017 · University of Cambridge · DOI

Full title: Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint

Authors: Liu, Y; Gill, E; Shery Huang, YY

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/263575

Thesis Challenges and Opportunities in Central Nervous System Drug Discovery

Danon, JJ; Reekie, TA; https://orcid.org/0000-0003-1415-8880 et al. · 2019 · UNSW Sydney · DOI

Full title: Challenges and Opportunities in Central Nervous System Drug Discovery

Authors: Danon, JJ; Reekie, TA ; https://orcid.org/0000-0003-1415-8880; Kassiou, M

Year: 2019

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_81549

Thesis Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties.

Baert, Yoni; De Kock, Joery; Alves-Lopes, João P et al. · 2019 · University of Cambridge · DOI

Full title: Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties.

Authors: Baert, Yoni; De Kock, Joery; Alves-Lopes, João P; Söder, Olle; Stukenborg, Jan-Bernd; Goossens, Ellen

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/299749

Thesis Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

Proctor, William R; Foster, Alison J; Vogt, Jennifer et al. · 2017 · University of Cambridge · DOI

Full title: Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

Authors: Proctor, William R; Foster, Alison J; Vogt, Jennifer; Summers, Claire; Middleton, Brian; Pilling, Mark A; Shienson, Daniel; Kijanska, Monika; Ströbel, Simon; Kelm, Jens M; Morgan, Paul; Messner, Simon; Williams, Dominic

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/266637

Thesis Disease modelling in human organoids.

Lancaster, Madeline A; Huch, Meritxell · 2019 · University of Cambridge · DOI

Full title: Disease modelling in human organoids.

Authors: Lancaster, Madeline A; Huch, Meritxell

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/294114

Thesis A planar impedance sensor for 3D spheroids.

Curto, VF; Ferro, MP; Mariani, F et al. · 2018 · University of Cambridge · DOI

Full title: A planar impedance sensor for 3D spheroids.

Authors: Curto, VF; Ferro, MP; Mariani, F; Scavetta, E; Owens, RM

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/287278

Thesis Functional patient-derived cellular models for neuropsychiatric drug discovery.

Lago, Santiago G; Tomasik, Jakub; Bahn, Sabine · 2021 · University of Cambridge · DOI

Full title: Functional patient-derived cellular models for neuropsychiatric drug discovery.

Authors: Lago, Santiago G; Tomasik, Jakub; Bahn, Sabine

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/319750

Thesis Organoids: a promising new in vitro platform in livestock and veterinary research.

Kar, Soumya K; Wells, Jerry M; Ellen, Esther D et al. · 2021 · University of Cambridge · DOI

Full title: Organoids: a promising new in vitro platform in livestock and veterinary research.

Authors: Kar, Soumya K; Wells, Jerry M; Ellen, Esther D; Te Pas, Marinus FW; Madsen, Ole; Groenen, Martien AM; Woelders, Henri

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/319759

Thesis Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.

Georgakopoulos, Nikitas; Prior, Nicole; Angres, Brigitte et al. · 2020 · University of Cambridge · DOI

Full title: Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.

Authors: Georgakopoulos, Nikitas; Prior, Nicole; Angres, Brigitte; Mastrogiovanni, Gianmarco; Cagan, Alex; Harrison, Daisy; Hindley, Christopher J; Arnes-Benito, Robert; Liau, Siong-Seng; Curd, Abbie; Ivory, Natasha; Simons, Benjamin D; Martincorena, Inigo; Wurst, Helmut; Saeb-Parsy, Kourosh; Huch, Meritxell

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/303876

Thesis Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Awatade, Nikhil; Wong, Sharon; Jaffe, Adam et al. · 2018 · UNSW Sydney · DOI

Full title: Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Authors: Awatade, Nikhil; Wong, Sharon; Jaffe, Adam ; https://orcid.org/0000-0002-1963-5415; Waters, Shafagh ; https://orcid.org/0000-0003-1144-5411; Fawcett, Laura ; https://orcid.org/0000-0001-7069-6179

Year: 2018

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_54892

Thesis In Vitro Models for Studying Respiratory Host-Pathogen Interactions.

Barron, Sarah L; Saez, Janire; Owens, Róisín M · 2021 · University of Cambridge · DOI

Full title: In Vitro Models for Studying Respiratory Host-Pathogen Interactions.

Authors: Barron, Sarah L; Saez, Janire; Owens, Róisín M

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/329890

Thesis Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.

Pitsalidis, Charalampos; van Niekerk, Douglas; Moysidou, Chrysanthi-Maria et al. · 2022 · University of Cambridge · DOI

Full title: Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.

Authors: Pitsalidis, Charalampos; van Niekerk, Douglas; Moysidou, Chrysanthi-Maria; Boys, Alexander J; Withers, Aimee; Vallet, Romane; Owens, Róisín M

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/342244

Thesis Immunogenicity of autologous and allogeneic human primary cholangiocyte organoid cellular therapies.

Petrus-Reurer, Sandra; Lei, Winnie; Tysoe, Olivia et al. · 2025 · University of Cambridge · DOI

Full title: Immunogenicity of autologous and allogeneic human primary cholangiocyte organoid cellular therapies.

Authors: Petrus-Reurer, Sandra; Lei, Winnie; Tysoe, Olivia; Mairesse, Maelle; Baez-Ortega, Adrian; Jones, Julia; Tan, Thomas; Rehakova, Sylvia; Mahbubani, Krishnaa T; Brodie, Cara; Han, Namshik; Martincorena, Inigo; Betts, Catherine; Vallier, Ludovic; Saeb-Parsy, Kourosh

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/385872

Thesis Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture.

Barron, Sarah L; Wyatt, Owen; O'Connor, Andy et al. · 2024 · University of Cambridge · DOI

Full title: Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture.

Authors: Barron, Sarah L; Wyatt, Owen; O'Connor, Andy; Mansfield, David; Suzanne Cohen, E; Witkos, Tomasz M; Strickson, Sam; Owens, Róisín M

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/362890

Thesis A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer.

Inglebert, Marine; Dettwiler, Martina; Hahn, Kerstin et al. · 2022 · University of Cambridge · DOI

Full title: A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer.

Authors: Inglebert, Marine; Dettwiler, Martina; Hahn, Kerstin; Letko, Anna; Drogemuller, Cord; Doench, John; Brown, Adam; Memari, Yasin; Davies, Helen R; Degasperi, Andrea; Nik-Zainal, Serena; Rottenberg, Sven

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/342593

Thesis Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

Wilson, AA; Ying, L; Liesa, M et al. · 2025 · University of Cambridge · DOI

Full title: Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

Authors: Wilson, AA; Ying, L; Liesa, M; Segeritz, CP; Mills, JA; Shen, SS; Jean, J; Lonza, GC; Liberti, DC; Lang, AH; Nazaire, J; Gower, AC; Müeller, FJ; Mehta, P; Ordóñez, A; Lomas, DA; Vallier, L; Murphy, GJ; Mostoslavsky, G; Spira, A; Shirihai, OS; Ramirez, MI; Gadue, P; Kotton, DN

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/378776

Thesis Modeling human disease with pluripotent stem cells: from genome association to function.

Merkle, Florian T; Eggan, Kevin · 2025 · University of Cambridge · DOI

Full title: Modeling human disease with pluripotent stem cells: from genome association to function.

Authors: Merkle, Florian T; Eggan, Kevin

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/378954

Thesis Establishing predictive machine learning models for drug responses in patient derived cell culture.

Abdel-Rehim, Abbi; Orhobor, Oghenejokpeme; Griffiths, Gareth et al. · 2025 · University of Cambridge · DOI

Full title: Establishing predictive machine learning models for drug responses in patient derived cell culture.

Authors: Abdel-Rehim, Abbi; Orhobor, Oghenejokpeme; Griffiths, Gareth; Soldatova, Larisa; King, Ross D

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/384213

Thesis Porous scaffolds for in vitro modelling and monitoring of the extracellular matrix

Owens, Roisin · 2025 · University of Cambridge · DOI

Full title: Porous scaffolds for in vitro modelling and monitoring of the extracellular matrix

Authors: Owens, Roisin

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/392583

Thesis Ex-vivo model to stimulate nasal tissue and new therapeutic targets

Patou, Joke · 2011 · Ghent University (Universiteit Gent) · DOI

Full title: Ex-vivo model to stimulate nasal tissue and new therapeutic targets

Authors: Patou, Joke

Year: 2011

Venue: Ghent University (Universiteit Gent)

DOI: https://biblio.ugent.be/publication/8530265

Thesis How in vitro alterations in cellular energy pathways can overcome obstacles in drug research

Seeland, Swen · 2013 · Heidelberg University · DOI

Full title: How in vitro alterations in cellular energy pathways can overcome obstacles in drug research

Authors: Seeland, Swen

Year: 2013

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/15626/1/Dissertation_Uni_HD_Swen_Seeland_%28Oktober_2012%29.pdf

Thesis Toxicogenomic approaches for the prediction of hepatotoxicity in vitro

Hrach, Jens · 2009 · Heidelberg University · DOI

Full title: Toxicogenomic approaches for the prediction of hepatotoxicity in vitro

Authors: Hrach, Jens

Year: 2009

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/9204/1/Dissertation_Jens_Hrach.pdf

Thesis Entwicklung von mikrofluidischen Multi-Organ-Zellchipsystemen für die in vitro Metabolisierung und Bestimmung der Toxizität von Substanzen

Theobald, Jannick Florian · 2018 · Heidelberg University · DOI

Full title: Entwicklung von mikrofluidischen Multi-Organ-Zellchipsystemen für die in vitro Metabolisierung und Bestimmung der Toxizität von Substanzen

Authors: Theobald, Jannick Florian

Year: 2018

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/25215/7/28052018%20Thesis%20Gesamt%20jft.pdf

Thesis Gen- und Proteinexpressionsanalysen an primären Rattenhepatozyten

Beigel, Jürgen · 2005 · Heidelberg University · DOI

Full title: Gen- und Proteinexpressionsanalysen an primären Rattenhepatozyten

Authors: Beigel, Jürgen

Year: 2005

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/6103/1/Dissertation.Juergen.Beigel.pdf

Thesis Human Orthotopic and Metastatic Lung Cancer-on-Chip Models

Hassell, Bryan · 2019 · Harvard University - DASH · DOI

Full title: Human Orthotopic and Metastatic Lung Cancer-on-Chip Models

Authors: Hassell, Bryan

Year: 2019

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:39987883

Thesis Evaluating the Clearance of Common Extra-label Drug Combinations by Turkey Hepatocytes in Primary Culture

Lyster, Samantha · 2020 · University of Guelph · DOI

Full title: Evaluating the Clearance of Common Extra-label Drug Combinations by Turkey Hepatocytes in Primary Culture

Authors: Lyster, Samantha

Year: 2020

Venue: University of Guelph

DOI: https://hdl.handle.net/10214/20732

Thesis Vascularized, Immune-Infiltrated, and Perfusable Kidney Organoid-on-Chip Models

Kroll, Katharina Theresa · 2023 · Harvard University - DASH · DOI

Full title: Vascularized, Immune-Infiltrated, and Perfusable Kidney Organoid-on-Chip Models

Authors: Kroll, Katharina Theresa

Year: 2023

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375560

Thesis Development of a quick, robust and chemically-defined differentiation protocol from human induced pluripotent stem cells towards cortical neurons to phenotype Alzheimer’s Disease

Kowalski, Alexandra · 2020 · Heidelberg University · DOI

Full title: Development of a quick, robust and chemically-defined differentiation protocol from human induced pluripotent stem cells towards cortical neurons to phenotype Alzheimer’s Disease

Authors: Kowalski, Alexandra

Year: 2020

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/27918/1/DoctoralThesisAlexandraKowalski2019.pdf

Thesis Phenotypic High-Throughput Screening to Identify Small-Molecule Inhibitors of Beta-Cell Glucolipotoxicity

Small, Jonnell Candice · 2022 · Harvard University - DASH · DOI

Full title: Phenotypic High-Throughput Screening to Identify Small-Molecule Inhibitors of Beta-Cell Glucolipotoxicity

Authors: Small, Jonnell Candice

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371930

Thesis Development of a novel human co-culture model to study interactions between intestinal immune and epithelial cells

Steinhauer, Michelle · 2024 · Heidelberg University · DOI

Full title: Development of a novel human co-culture model to study interactions between intestinal immune and epithelial cells

Authors: Steinhauer, Michelle

Year: 2024

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34307/1/231020_PhD%20thesis_Michelle%20Steinhauer.pdf

Thesis Unraveling the Molecular and Cellular Complexities of the Kidney in Health and Disease

Sidhom, Eriene-Heidi · 2019 · Harvard University - DASH · DOI

Full title: Unraveling the Molecular and Cellular Complexities of the Kidney in Health and Disease

Authors: Sidhom, Eriene-Heidi

Year: 2019

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42029547

Thesis Human In Vitro Models of Pediatric Muscular Diseases

Nesmith, Alexander Peyton · 2018 · Harvard University - DASH · DOI

Full title: Human In Vitro Models of Pediatric Muscular Diseases

Authors: Nesmith, Alexander Peyton

Year: 2018

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:37944973

Thesis Elucidating Human Disease Mechanisms Using Innovative Open Microfluidic Platforms

Zeng, Yuting · 2024 · University of Washington - ResearchWorks · DOI

Full title: Elucidating Human Disease Mechanisms Using Innovative Open Microfluidic Platforms

Authors: Zeng, Yuting

Year: 2024

Venue: University of Washington - ResearchWorks

DOI: https://hdl.handle.net/1773/52441

Thesis Proteomics informed investigation of human hepatocytes and liver tissue

Handin, Niklas · 2021 · Uppsala University · DOI

Full title: Proteomics informed investigation of human hepatocytes and liver tissue

Authors: Handin, Niklas

Year: 2021

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-446954

Thesis Recreating the microenvironment of the neurovascular unit

Matthiesen, Isabelle · 2022 · KTH Royal Institute of Technology · DOI

Full title: Recreating the microenvironment of the neurovascular unit

Authors: Matthiesen, Isabelle

Year: 2022

Venue: KTH Royal Institute of Technology

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-310606

Thesis Development and Characterization of a Human Intestinal Organoid Monolayer Model to Predict Oral Drug Disposition

Arian, Christopher Michael · 2025 · University of Washington - ResearchWorks · DOI

Full title: Development and Characterization of a Human Intestinal Organoid Monolayer Model to Predict Oral Drug Disposition

Authors: Arian, Christopher Michael

Year: 2025

Venue: University of Washington - ResearchWorks

DOI: https://hdl.handle.net/1773/52855

Thesis Accelerating the discovery of drugs for Neglected Tropical Diseases using biophysical methods

Opassi, Giulia · 2020 · Uppsala University · DOI

Full title: Accelerating the discovery of drugs for Neglected Tropical Diseases using biophysical methods

Authors: Opassi, Giulia

Year: 2020

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408721

Thesis Insights into Polycystic Kidney Disease : In Vitro Models, Proteome Analyses and Drug Repurposing

Meyer, Alina · 2025 · Uppsala University · DOI

Full title: Insights into Polycystic Kidney Disease : In Vitro Models, Proteome Analyses and Drug Repurposing

Authors: Meyer, Alina

Year: 2025

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-564615

Thesis Advanced In Vitro Systems for Studies of Drug Disposition in the Human Liver

Mickols, Evgeniya · 2025 · Uppsala University · DOI

Full title: Advanced In Vitro Systems for Studies of Drug Disposition in the Human Liver

Authors: Mickols, Evgeniya

Year: 2025

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-548596

Thesis Microfluidic in vitro model to study cell mechanisms and drug efficacy

Nishanth Venugopal Menon · 2015 · Nanyang Technological University (NTU) · DOI

Full title: Microfluidic in vitro model to study cell mechanisms and drug efficacy

Authors: Nishanth Venugopal Menon

Year: 2015

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/65723

Thesis Why animal studies are still being used in drug development. An innovation system perspective

Kooijman, M. · 2013 · Utrecht University · DOI

Full title: Why animal studies are still being used in drug development. An innovation system perspective

Authors: Kooijman, M.

Year: 2013

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/287829

Thesis Building the colon epithelial microenvironment in vitro for investigation of intestinal disease mechanisms

Massaro, Angelo · 2025 · University of Washington - ResearchWorks · DOI

Full title: Building the colon epithelial microenvironment in vitro for investigation of intestinal disease mechanisms

Authors: Massaro, Angelo

Year: 2025

Venue: University of Washington - ResearchWorks

DOI: https://hdl.handle.net/1773/52721

Thesis A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report

Basketter, D.A.; Clewell, H.; Kimber, I. et al. · 2012 · Utrecht University · DOI

Full title: A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report

Authors: Basketter, D.A.; Clewell, H.; Kimber, I.; Rossi, A.; Blaauboer, B.J.; Burrier, R.; Daneshian, M.; Eskes, C.; Goldberg, A.; Hasiwa, N.

Year: 2012

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/274141

Thesis Intestinal organoids as model for cystic fibrosis

Dekkers, J.F. · 2015 · Utrecht University · DOI

Full title: Intestinal organoids as model for cystic fibrosis

Authors: Dekkers, J.F.

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/321710

Thesis Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Marx, Uwe; Andersson, Tommy B; Bahinski, Anthony et al. · 2016 · Utrecht University · DOI

Full title: Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Authors: Marx, Uwe; Andersson, Tommy B; Bahinski, Anthony; Beilmann, Mario; Beken, Sonja; Cassee, Flemming R; Cirit, Murat; Daneshian, Mardas; Fitzpatrick, Susan; Frey, Olivier; Gaertner, Claudia; Giese, Christoph; Griffith, Linda; Hartung, Thomas; Heringa, Minne B; Hoeng, Julia; de Jong, Wim H; Kojima, Hajime; Kuehnl, Jochen; Leist, Marcel; Luch, Andreas; Maschmeyer, Ilka; Sakharov, Dmitry; Sips, Adrienne J A M; Steger-Hartmann, Thomas; Tagle, Danilo A; Tonevitsky, Alexander; Tralau, Tewes; Tsyb, Sergej; van de Stolpe, Anja; Vandebriel, Rob; Vulto, Paul; Wang, Jufeng; Wiest, Joachim; Rodenburg, Marleen; Roth, Adrian

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/344409

Thesis Adult Stem Cell-Derived Kidney Organoids to Model Tissue Physiology and Disease

Schutgens, F.W.G. · 2017 · Utrecht University · DOI

Full title: Adult Stem Cell-Derived Kidney Organoids to Model Tissue Physiology and Disease

Authors: Schutgens, F.W.G.

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/357191

Thesis Application of human organoids in ion transport studies

Zomer-van Ommen, D.D. · 2018 · Utrecht University · DOI

Full title: Application of human organoids in ion transport studies

Authors: Zomer-van Ommen, D.D.

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/364743

Thesis Optimizing drug discovery by Investigative Toxicology: Current and future trends

Beilmann, Mario; Boonen, Harrie; Czich, Andreas et al. · 2019 · Utrecht University · DOI

Full title: Optimizing drug discovery by Investigative Toxicology: Current and future trends

Authors: Beilmann, Mario; Boonen, Harrie; Czich, Andreas; Dear, Gordon; Hewitt, Philip; Mow, Tomas; Newham, Peter; Oinonen, Teija; Pognan, Francois; Roth, Adrian; Valentin, Jean-Pierre; Van Goethem, Freddy; Weaver, Richard J; Birk, Barbara; Boyer, Scott; Caloni, Francesca; Chen, Alice E; Corvi, Raffaella; Cronin, Mark T D; Daneshian, Mardas; Ewart, Lorna C; Fitzgerald, Rex E; Hamilton, Geraldine A; Hartung, Thomas; Kangas, Joshua D; Kramer, Nynke I; Leist, Marcel; Marx, Uwe; Polak, Sebastian; Rovida, Costanza; Testai, Emanuela; Van der Water, Bob; Vulto, Paul; Steger-Hartmann, Thomas

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/381420

Thesis Utilizing organoids to study general and tissue-specific adult stem cell profiles: Exploiting organoid cultures for basic stem cell research

Boonekamp, Kim Elisabeth · 2020 · Utrecht University · DOI

Full title: Utilizing organoids to study general and tissue-specific adult stem cell profiles: Exploiting organoid cultures for basic stem cell research

Authors: Boonekamp, Kim Elisabeth

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/399221

Thesis Personalizing CFTR modulator therapies

Berkers, Gitte · 2020 · Utrecht University · DOI

Full title: Personalizing CFTR modulator therapies

Authors: Berkers, Gitte

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/400837

Thesis Precision medicine for Cystic Fibrosis using intestinal organoids

Mourik, Peter van · 2021 · Utrecht University · DOI

Full title: Precision medicine for Cystic Fibrosis using intestinal organoids

Authors: Mourik, Peter van

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/416554

Thesis Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do

Ribitsch, Iris; Baptista, Pedro M; Lange-Consiglio, Anna et al. · 2020 · Utrecht University · DOI

Full title: Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do

Authors: Ribitsch, Iris; Baptista, Pedro M; Lange-Consiglio, Anna; Melotti, Luca; Patruno, Marco; Jenner, Florien; Schnabl-Feichter, Eva; Dutton, Luke C; Connolly, David J; van Steenbeek, Frank G; Dudhia, Jayesh; Penning, Louis C

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/410152

Thesis Modelling of a wide variety of disease using adult stem cell-derived organoids

Vaart, Jelte Yoran van der · 2022 · Utrecht University · DOI

Full title: Modelling of a wide variety of disease using adult stem cell-derived organoids

Authors: Vaart, Jelte Yoran van der

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/416576

Thesis Selection of animal models for drug efficacy

Veening - Griffioen, Desiree · 2023 · Utrecht University · DOI

Full title: Selection of animal models for drug efficacy

Authors: Veening - Griffioen, Desiree

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426641

Thesis Bioengineering hepatic organoids: Development of an alternative model for liver toxicity

Bouwmeester, Manon Christel · 2023 · Utrecht University · DOI

Full title: Bioengineering hepatic organoids: Development of an alternative model for liver toxicity

Authors: Bouwmeester, Manon Christel

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/433481

Thesis Crafting Tissue Complexity: Pioneering Layerwise and Volumetric Biofabrication Strategies for Advanced In Vitro Models

Núñez Bernal, Paulina · 2024 · Utrecht University · DOI

Full title: Crafting Tissue Complexity: Pioneering Layerwise and Volumetric Biofabrication Strategies for Advanced In Vitro Models

Authors: Núñez Bernal, Paulina

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/433677

Thesis Paving the road towards the Next Generation Risk Assessment: Quantitative in vitro to in vivo extrapolations for the pre-diction of human toxicity based on alternative testing

Fragki, Styliani · 2023 · Utrecht University · DOI

Full title: Paving the road towards the Next Generation Risk Assessment: Quantitative in vitro to in vivo extrapolations for the pre-diction of human toxicity based on alternative testing

Authors: Fragki, Styliani

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/438153

Thesis Nasal epithelial cells as model for cystic fibrosis

Rodenburg, Lisa Willemijn · 2024 · Utrecht University · DOI

Full title: Nasal epithelial cells as model for cystic fibrosis

Authors: Rodenburg, Lisa Willemijn

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/433622

Thesis In Vitro Porcine (Explant) Colon Culture

de Oliveira Costa, Matheus; Dame, Michael K. · 2024 · Utrecht University · DOI

Full title: In Vitro Porcine (Explant) Colon Culture

Authors: de Oliveira Costa, Matheus; Dame, Michael K.

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/438349

Thesis Non-human primates in biomedical research : reasons and alternatives for their use

Pieters, F. · 2007 · Utrecht University · DOI

Full title: Non-human primates in biomedical research : reasons and alternatives for their use

Authors: Pieters, F.

Year: 2007

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/44806

Thesis Alternatives to animal research: from in vitro to ex vivo liver models

Krüger, Melanie · 2024 · Utrecht University · DOI

Full title: Alternatives to animal research: from in vitro to ex vivo liver models

Authors: Krüger, Melanie

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/455689

Thesis Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders

Dutan Polit, Lucia; Eidhof, Ilse; McNeill, Rhiannon V. et al. · 2023 · Utrecht University · DOI

Full title: Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders

Authors: Dutan Polit, Lucia; Eidhof, Ilse; McNeill, Rhiannon V.; Warre-Cornish, Katherine M.; Yde Ohki, Cristine Marie; Walter, Natalie Monet; Sala, Carlo; Verpelli, Chiara; Radtke, Franziska; Galderisi, Silvana; Mucci, Armida; Collo, Ginetta; Edenhofer, Frank; Castrén, Maija L.; Réthelyi, János M.; Ejlersen, Morten; Hohmann, Sonja Simone; Ilieva, Mirolyuba S.; Lukjanska, Renate; Matuleviciute, Rugile; Michel, Tanja Maria; de Vrij, Femke M.S.; Kushner, Steven A.; Lendemeijer, Bas; Kittel-Schneider, Sarah; Ziegler, Georg C.; Gruber-Schoffnegger, Doris; Pasterkamp, R. Jeroen; Kasri, Amal; Potier, Marie Claude; Knoblich, Jürgen A.; Brüstle, Oliver; Peitz, Michael; Pich, Emilio Merlo; Harwood, Adrian J.; Abranches, Elsa; Falk, Anna; Vernon, Anthony C.; Grünblatt, Edna; Srivastava, Deepak P.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/459427

Thesis Dual perspectives: Cellular differentiation in health and disease

DeMartino, Jeffrey Ross · 2024 · Utrecht University · DOI

Full title: Dual perspectives: Cellular differentiation in health and disease

Authors: DeMartino, Jeffrey Ross

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/456590

Thesis Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

· 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133522

Thesis High throughput measurement and perturbation of tissues and tissue-derived cellular models

Kummerlowe, Conner Samuel · 2023 · Massachusetts Institute of Technology (MIT) · DOI

Full title: High throughput measurement and perturbation of tissues and tissue-derived cellular models

Authors: Kummerlowe, Conner Samuel

Year: 2023

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/147420

Thesis Bioreactor technologies to support liver function in vitro

Neiman, Jaclyn A. Shepard; Hughes, David J.; Griffith, Linda G. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Bioreactor technologies to support liver function in vitro

Authors: Neiman, Jaclyn A. Shepard; Hughes, David J.; Griffith, Linda G.; Ebrahimkhani, Mohammad Reza; Raredon, Micha Sam Brickman

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/99380

Thesis Charakterisierung und Anwendung von in vitro und ex vivo Kultursystemen des oberen und unteren Respirationstraktes zur Erforschung der SARS-CoV-2 Empfänglichkeit bei verschiedenen Spezies unter Berücksichtigung des 3R Grundsatzes

Lockow, Sandra Sina · 2023 · University of Veterinary Medicine Hannover (TiHo) · DOI

Full title: Charakterisierung und Anwendung von in vitro und ex vivo Kultursystemen des oberen und unteren Respirationstraktes zur Erforschung der SARS-CoV-2 Empfänglichkeit bei verschiedenen Spezies unter Berücksichtigung des 3R Grundsatzes

Authors: Lockow, Sandra Sina

Year: 2023

Venue: University of Veterinary Medicine Hannover (TiHo)

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-119605

Thesis In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury

Granitzny, Anne · 2017 · University of Veterinary Medicine Hannover (TiHo) · DOI

Full title: In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury

Authors: Granitzny, Anne

Year: 2017

Venue: University of Veterinary Medicine Hannover (TiHo)

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-110521

Thesis Programmable systems to engineer human tissues and electrophysiological sensors

Parekh, Udit · 2021 · University of California, San Diego (UCSD) · DOI

Full title: Programmable systems to engineer human tissues and electrophysiological sensors

Authors: Parekh, Udit

Year: 2021

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0rw1h5q2

Thesis Development of a scalable in-vivo drug discovery platform allows for deep interrogation of mechanisms of KRAS.G12C inhibitors.

Yu, John Xuzong · 2022 · University of California, San Francisco (UCSF) · DOI

Full title: Development of a scalable in-vivo drug discovery platform allows for deep interrogation of mechanisms of KRAS.G12C inhibitors.

Authors: Yu, John Xuzong

Year: 2022

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/17w596v6

Thesis Organs and Humans on Chips: Translation, Biomedical Models, and the Political Economy of Innovation

Jeske, Melanie S · 2022 · University of California, San Francisco (UCSF) · DOI

Full title: Organs and Humans on Chips: Translation, Biomedical Models, and the Political Economy of Innovation

Authors: Jeske, Melanie S

Year: 2022

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/1619z088

Thesis High-content array based screening technology for the identification of factors that regulate cell fate

Brafman, David Adam · 2009 · University of California, San Diego (UCSD) · DOI

Full title: High-content array based screening technology for the identification of factors that regulate cell fate

Authors: Brafman, David Adam

Year: 2009

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/3gw8w75m

Thesis HNF4 alpha bioactive ligands discovered by a high- throughput screen for modulators of the human insulin promoter

Kiselyuk, Alice Susan · 2011 · University of California, San Diego (UCSD) · DOI

Full title: HNF4 alpha bioactive ligands discovered by a high- throughput screen for modulators of the human insulin promoter

Authors: Kiselyuk, Alice Susan

Year: 2011

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/64k4q3gr

Thesis RAPID 3D BIOPRINTING OF BIOMIMETIC LIVER TISSUES FOR MODELING HEALTHY AND DISEASE STATES IN VITRO

Ma, Xuanyi · 2018 · University of California, San Diego (UCSD) · DOI

Full title: RAPID 3D BIOPRINTING OF BIOMIMETIC LIVER TISSUES FOR MODELING HEALTHY AND DISEASE STATES IN VITRO

Authors: Ma, Xuanyi

Year: 2018

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0z647878

Thesis Micropatterned co-cultures of hepatocytes and nonparenchymal cells : mechanisms of differentiation, dynamics and applications

Khetani, Salman R. · 2006 · University of California, San Diego (UCSD) · DOI

Full title: Micropatterned co-cultures of hepatocytes and nonparenchymal cells : mechanisms of differentiation, dynamics and applications

Authors: Khetani, Salman R.

Year: 2006

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/9g06w180

Thesis A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

Nguyen, Vivian V T; Ye, Shicheng; Gkouzioti, Vasiliki et al. · 2022 · Utrecht University · DOI

Full title: A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

Authors: Nguyen, Vivian V T; Ye, Shicheng; Gkouzioti, Vasiliki; van Wolferen, Monique E; Yengej, Fjodor Yousef; Melkert, Dennis; Siti, Sofia; de Jong, Bart; Besseling, Paul J; Spee, Bart; van der Laan, Luc J W; Horland, Reyk; Verhaar, Marianne C; van Balkom, Bas W M

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/424297

Thesis Tissue Engineered Bile Ducts for Disease Modeling and Therapy

Wang, Zhenguo; Faria, Joao; Penning, Louis et al. · 2021 · Utrecht University · DOI

Full title: Tissue Engineered Bile Ducts for Disease Modeling and Therapy

Authors: Wang, Zhenguo; Faria, Joao; Penning, Louis; Masereeuw, Roos; Spee, Bart

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/432277

Thesis Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants

Amirabadi, Hossein Eslami; Donkers, Joanne M.; Wierenga, Esmée et al. · 2022 · Utrecht University · DOI

Full title: Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants

Authors: Amirabadi, Hossein Eslami; Donkers, Joanne M.; Wierenga, Esmée; Ingenhut, Bastiaan; Pieters, Lisanne; Stevens, Lianne; Donkers, Tim; Westerhout, Joost; Masereeuw, Rosalinde; Bobeldijk-Pastorova, Ivana; Nooijen, Irene; Steeg, Evita van de

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/431716

Thesis Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro

Pscheid, Ronja; Drent, Esther; Wienke, Judith et al. · 2023 · Utrecht University · DOI

Full title: Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro

Authors: Pscheid, Ronja; Drent, Esther; Wienke, Judith; Strijker, Josephine G.M.; Throsby, Mark; Molenaar, Jan J.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/435873

Thesis New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

Punt, Ans; Bouwmeester, Hans; Blaauboer, Bas J et al. · 2020 · Utrecht University · DOI

Full title: New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

Authors: Punt, Ans; Bouwmeester, Hans; Blaauboer, Bas J; Coecke, Sandra; Hakkert, Betty; Hendriks, Delilah F G; Jennings, Paul; Kramer, Nynke I; Neuhoff, Sibylle; Masereeuw, Rosalinde; Paini, Alicia; Peijnenburg, Ad A C M; Rooseboom, Martijn; Shuler, Michael L; Sorrell, Ian; Spee, Bart; Strikwold, Marije; Van der Meer, Andries D; Van der Zande, Meike; Vinken, Mathieu; Yang, Huan; Bos, Peter M J; Heringa, Minne B

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/432487

Thesis Kidney Organoids and Tubuloids

Yousef Yengej, Fjodor A; Jansen, Jitske; Rookmaaker, Maarten B et al. · 2020 · Utrecht University · DOI

Full title: Kidney Organoids and Tubuloids

Authors: Yousef Yengej, Fjodor A; Jansen, Jitske; Rookmaaker, Maarten B; Verhaar, Marianne C; Clevers, Hans

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439818

Thesis Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

Giobbe, Giovanni Giuseppe; Crowley, Claire; Luni, Camilla et al. · 2019 · Utrecht University · DOI

Full title: Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

Authors: Giobbe, Giovanni Giuseppe; Crowley, Claire; Luni, Camilla; Campinoti, Sara; Khedr, Moustafa; Kretzschmar, Kai; De Santis, Martina Maria; Zambaiti, Elisa; Michielin, Federica; Meran, Laween; Hu, Qianjiang; van Son, Gijs; Urbani, Luca; Manfredi, Anna; Giomo, Monica; Eaton, Simon; Cacchiarelli, Davide; Li, Vivian S.W.; Clevers, Hans; Bonfanti, Paola; Elvassore, Nicola; De Coppi, Paolo

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439401

Thesis Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

Akbari, Soheil; Sevinç, Gülben Gürhan; Ersoy, Nevin et al. · 2019 · Utrecht University · DOI

Full title: Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

Authors: Akbari, Soheil; Sevinç, Gülben Gürhan; Ersoy, Nevin; Basak, Onur; Kaplan, Kubra; Sevinç, Kenan; Ozel, Erkin; Sengun, Berke; Enustun, Eray; Ozcimen, Burcu; Bagriyanik, Alper; Arslan, Nur; Önder, Tamer Tevfik; Erdal, Esra

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439393

Thesis Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

Vonk, Annelotte M; van Mourik, Peter; Ramalho, Anabela S et al. · 2020 · Utrecht University · DOI

Full title: Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

Authors: Vonk, Annelotte M; van Mourik, Peter; Ramalho, Anabela S; Silva, Iris A L; Statia, Marvin; Kruisselbrink, Evelien; Suen, Sylvia W F; Dekkers, Johanna F; Vleggaar, Frank P; Houwen, Roderick H J; Mullenders, Jasper; Boj, Sylvia F; Vries, Robert; Amaral, Margarida D; de Boeck, Kris; van der Ent, Cornelis K; Beekman, Jeffrey M

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440961

Thesis Organoids for personalized treatment of Cystic Fibrosis: Professional perspectives on the ethics and governance of organoid biobanking

Lensink, Michael A; Boers, Sarah N; Jongsma, Karin R et al. · 2021 · Utrecht University · DOI

Full title: Organoids for personalized treatment of Cystic Fibrosis: Professional perspectives on the ethics and governance of organoid biobanking

Authors: Lensink, Michael A; Boers, Sarah N; Jongsma, Karin R; Carter, Sarah E; van der Ent, Cornelis K; Bredenoord, Annelien L

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/441358

Thesis Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

Ringel, Till; Frey, Nina; Ringnalda, Femke et al. · 2020 · Utrecht University · DOI

Full title: Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

Authors: Ringel, Till; Frey, Nina; Ringnalda, Femke; Janjuha, Sharan; Cherkaoui, Sarah; Butz, Stefan; Srivatsa, Sumana; Pirkl, Martin; Russo, Giancarlo; Villiger, Lukas; Rogler, Gerhard; Clevers, Hans; Beerenwinkel, Niko; Zamboni, Nicola; Baubec, Tuncay; Schwank, Gerald

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/442165

Thesis An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells

Lamers, Mart M; van der Vaart, Jelte; Knoops, Kèvin et al. · 2021 · Utrecht University · DOI

Full title: An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells

Authors: Lamers, Mart M; van der Vaart, Jelte; Knoops, Kèvin; Riesebosch, Samra; Breugem, Tim I; Mykytyn, Anna Z; Beumer, Joep; Schipper, Debby; Bezstarosti, Karel; Koopman, Charlotte D; Groen, Nathalie; Ravelli, Raimond B G; Duimel, Hans Q; Demmers, Jeroen A A; Verjans, Georges M G M; Koopmans, Marion P G; Muraro, Mauro J; Peters, Peter J; Clevers, Hans; Haagmans, Bart L

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/442177

Thesis Stem cells, organoids, and organ-on-a-chip models for personalized in vitro drug testing

van Berlo, Damiën; Nguyen, Vivian V.T.; Gkouzioti, Vasiliki et al. · 2021 · Utrecht University · DOI

Full title: Stem cells, organoids, and organ-on-a-chip models for personalized in vitro drug testing

Authors: van Berlo, Damiën; Nguyen, Vivian V.T.; Gkouzioti, Vasiliki; Leineweber, Kirsten; Verhaar, Marianne C.; van Balkom, Bas W.M.

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445270

Thesis Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

Maas, Renee G.C.; Lee, Soah; Harakalova, Magdalena et al. · 2021 · Utrecht University · DOI

Full title: Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

Authors: Maas, Renee G.C.; Lee, Soah; Harakalova, Magdalena; Snijders Blok, Christian J.B.; Goodyer, William R.; Hjortnaes, Jesper; Doevendans, Pieter A.F.M.; Van Laake, Linda W.; van der Velden, Jolanda; Asselbergs, Folkert W.; Wu, Joseph C.; Sluijter, Joost P.G.; Wu, Sean M.; Buikema, Jan W.

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445447

Thesis Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

De Crignis, Elisa; Hossain, Tanvir; Romal, Shahla et al. · 2021 · Utrecht University · DOI

Full title: Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

Authors: De Crignis, Elisa; Hossain, Tanvir; Romal, Shahla; Carofiglio, Fabrizia; Moulos, Panagiotis; Khalid, Mir Mubashir; Rao, Shringar; Bazrafshan, Ameneh; Verstegen, Monique M.A.; Pourfarzad, Farzin; Koutsothanassis, Christina; Gehart, Helmuth; Kan, Tsung Wai; Palstra, Robert Jan; Boucher, Charles; Ijzermans, Jan M.N.; Huch, Meritxell; Boj, Sylvia F.; Vries, Robert; Clevers, Hans; van der Laan, Luc; Hatzis, Pantelis; Mahmoudi, Tokameh

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445573

Thesis Development in a Dish—In Vitro Models of Mammalian Embryonic Development

el Azhar, Yasmine; Sonnen, Katharina F. · 2021 · Utrecht University · DOI

Full title: Development in a Dish—In Vitro Models of Mammalian Embryonic Development

Authors: el Azhar, Yasmine; Sonnen, Katharina F.

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445799

Thesis Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Amatngalim, Gimano D; Rodenburg, Lisa W; Aalbers, Bente L et al. · 2022 · Utrecht University · DOI

Full title: Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Authors: Amatngalim, Gimano D; Rodenburg, Lisa W; Aalbers, Bente L; Raeven, Henriette Hm; Aarts, Ellen M; Sarhane, Dounia; Spelier, Sacha; Lefferts, Juliet W; Silva, Iris Al; Nijenhuis, Wilco; Vrendenbarg, Sacha; Kruisselbrink, Evelien; Brunsveld, Jesse E; van Drunen, Cornelis M; Michel, Sabine; de Winter-de Groot, Karin M; Heijerman, Harry G; Kapitein, Lukas C; Amaral, Magarida D; van der Ent, Cornelis K; Beekman, Jeffrey M

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/446965

Thesis Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

Rodenburg, Lisa W.; Delpiano, Livia; Railean, Violeta et al. · 2022 · Utrecht University · DOI

Full title: Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

Authors: Rodenburg, Lisa W.; Delpiano, Livia; Railean, Violeta; Centeio, Raquel; Pinto, Madalena C.; Smits, Shannon M.A.; van der Windt, Isabelle S.; van Hugten, Casper F.J.; van Beuningen, Sam F.B.; Rodenburg, Remco N.P.; van der Ent, Cornelis K.; Amaral, Margarida D.; Kunzelmann, Karl; Gray, Michael A.; Beekman, Jeffrey M.; Amatngalim, Gimano D.

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447464

Thesis Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis

Bracco Gartner, Tom; Crnko, S; Leiteris, Laurynas et al. · 2022 · Utrecht University · DOI

Full title: Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis

Authors: Bracco Gartner, Tom; Crnko, S; Leiteris, Laurynas; van Adrichem, Iris; van Laake, Linda W.; Bouten, Carlijn V. C.; Goumans, Marie-Jose; Suyker, Willem; Sluijter, Joost P.G.; Hjortnaes, Jesper

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445941

Thesis Advancing lung organoids for COVID-19 research

van der Vaart, Jelte; Lamers, Mart M.; Haagmans, Bart L. et al. · 2021 · Utrecht University · DOI

Full title: Advancing lung organoids for COVID-19 research

Authors: van der Vaart, Jelte; Lamers, Mart M.; Haagmans, Bart L.; Clevers, Hans

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445781

Thesis 3D Human iPSC Blood Vessel Organoids as a Source of Flow-Adaptive Vascular Cells for Creating a Human-Relevant 3D-Scaffold Based Macrovessel Model

Meijer, Elana M; Koch, Suzanne E; van Dijk, Christian G M et al. · 2023 · Utrecht University · DOI

Full title: 3D Human iPSC Blood Vessel Organoids as a Source of Flow-Adaptive Vascular Cells for Creating a Human-Relevant 3D-Scaffold Based Macrovessel Model

Authors: Meijer, Elana M; Koch, Suzanne E; van Dijk, Christian G M; Maas, Renee G C; Chrifi, Ihsan; Szymczyk, Wojciech; Besseling, Paul J; Pomp, Lisa; Koomen, Vera J C H; Buikema, Jan Willem; Bouten, Carlijn V C; Verhaar, Marianne C; Smits, Anthal I P M; Cheng, Caroline

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447383

Thesis A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use

Ardisasmita, Arif Ibrahim; Schene, Imre F; Joore, Indi P et al. · 2022 · Utrecht University · DOI

Full title: A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use

Authors: Ardisasmita, Arif Ibrahim; Schene, Imre F; Joore, Indi P; Kok, Gautam; Hendriks, Delilah; Artegiani, Benedetta; Mokry, Michal; Nieuwenhuis, Edward E S; Fuchs, Sabine A

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447364

Thesis A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Beumer, Joep; Geurts, Maarten H.; Lamers, Mart M. et al. · 2021 · Utrecht University · DOI

Full title: A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Authors: Beumer, Joep; Geurts, Maarten H.; Lamers, Mart M.; Puschhof, Jens; Zhang, Jingshu; van der Vaart, Jelte; Mykytyn, Anna Z.; Breugem, Tim I.; Riesebosch, Samra; Schipper, Debby; van den Doel, Petra B.; de Lau, Wim; Pleguezuelos-Manzano, Cayetano; Busslinger, Georg; Haagmans, Bart L.; Clevers, Hans

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445608

Thesis A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Xu, Xiaoxi; Kumari, Rajendra; Zhou, Jun et al. · 2023 · Utrecht University · DOI

Full title: A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Authors: Xu, Xiaoxi; Kumari, Rajendra; Zhou, Jun; Chen, Jing; Mao, Binchen; Wang, Jingjing; Zheng, Meiling; Tu, Xiaolong; An, Xiaoyu; Chen, Xiaobo; Zhang, Likun; Tian, Xiaoli; Wang, Haojie; Dong, Xin; Bao, Zhengzheng; Guo, Sheng; Ouyang, Xuesong; Shang, Limei; Wang, Fei; Yan, Xuefei; Zhang, Rui; Vries, Robert G.J.; Clevers, Hans; Li, Qi Xiang

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/448336

Thesis High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

Spelier, Sacha; de Poel, Eyleen; Ithakisiou, Georgia N. et al. · 2023 · Utrecht University · DOI

Full title: High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

Authors: Spelier, Sacha; de Poel, Eyleen; Ithakisiou, Georgia N.; Suen, Sylvia W.F.; Hagemeijer, Marne C.; Muilwijk, Danya; Vonk, Annelotte M.; Brunsveld, Jesse E.; Kruisselbrink, Evelien; van der Ent, Cornelis K.; Beekman, Jeffrey M.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/449840

Thesis A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology

Nguyen, Vivian V T; Gkouzioti, Vasiliki; Maass, Christian et al. · 2023 · Utrecht University · DOI

Full title: A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology

Authors: Nguyen, Vivian V T; Gkouzioti, Vasiliki; Maass, Christian; Verhaar, Marianne C; Vernooij, Robin W M; van Balkom, Bas W M

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/449397

Thesis Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis

Birimberg-Schwartz, Liron; Ip, Wan; Bartlett, Claire et al. · 2023 · Utrecht University · DOI

Full title: Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis

Authors: Birimberg-Schwartz, Liron; Ip, Wan; Bartlett, Claire; Avolio, Julie; Vonk, Annelotte M.; Gunawardena, Tarini; Du, Kai; Esmaeili, Mohsen; Beekman, Jeffrey M.; Rommens, Johanna; Strug, Lisa; Bear, Christine E.; Moraes, Theo J.; Gonska, Tanja

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/449833

Thesis A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant

Chiu, Man Chun; Li, Cun; Liu, Xiaojuan et al. · 2022 · Utrecht University · DOI

Full title: A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant

Authors: Chiu, Man Chun; Li, Cun; Liu, Xiaojuan; Yu, Yifei; Huang, Jingjing; Wan, Zhixin; Xiao, Ding; Chu, Hin; Cai, Jian Piao; Zhou, Biao; Sit, Ko Yung; Au, Wing Kuk; Wong, Kenneth Kak Yuen; Li, Gang; Chan, Jasper Fuk Woo; To, Kelvin Kai Wang; Chen, Zhiwei; Jiang, Shibo; Clevers, Hans; Yuen, Kwok Yung; Zhou, Jie

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447934

Thesis Human liver organoids: From generation to applications

Afonso, Marta B; Marques, Vanda; van Mil, Saskia W C et al. · 2024 · Utrecht University · DOI

Full title: Human liver organoids: From generation to applications

Authors: Afonso, Marta B; Marques, Vanda; van Mil, Saskia W C; Rodrigues, Cecilia M P

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/453554

Thesis Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine

Langenberg, Karin P.S.; van Hooff, Sander R.; Koopmans, Bianca et al. · 2025 · Utrecht University · DOI

Full title: Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine

Authors: Langenberg, Karin P.S.; van Hooff, Sander R.; Koopmans, Bianca; Strijker, Josephine G.M.; Kholosy, Waleed M.; Ober, Kimberley; Zwijnenburg, Danny A.; van der Hoek, Jessica J.F.; Keller, Kaylee M.; Vernooij, Lindy; Schild, Linda G.; Looze, Eleonora J.; Ebus, Marli E.; Essing, Anke H.W.; Vree, Paula de; Tas, Michelle L.; Matser, Yvette A.H.; Wienke, Judith; Volckmann, Richard; Tops, Bastiaan B.J.; Kester, Lennart A.; Badloe, Shashi; Hehir-Kwa, Jayne Y.; Kemmeren, Patrick; Goemans, Bianca F.; Zwaan, C. Michel; Oehme, Ina; Jäger, Nathalie; Witt, Olaf; van Eijkelenburg, Natasha K.A.; Dierselhuis, Miranda P.; Tytgat, Godelieve A.M.; Wijnen, Marc H.W.; van Noesel, Max M.; de Krijger, Ronald R.; Eising, Selma; Koster, Jan; Dolman, Emmy M.; Molenaar, Jan J.

Year: 2025

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/460677

Thesis Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Hendriks, Delilah; Brouwers, Jos F.; Hamer, Karien et al. · 2023 · Utrecht University · DOI

Full title: Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Authors: Hendriks, Delilah; Brouwers, Jos F.; Hamer, Karien; Geurts, Maarten H.; Luciana, Léa; Massalini, Simone; López-Iglesias, Carmen; Peters, Peter J.; Rodríguez-Colman, Maria J.; Chuva de Sousa Lopes, Susana; Artegiani, Benedetta; Clevers, Hans

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451211

Thesis Recommendations for robust and reproducible preclinical research in personalised medicine

on behalf of The PERMIT group · 2023 · Utrecht University · DOI

Full title: Recommendations for robust and reproducible preclinical research in personalised medicine

Authors: on behalf of The PERMIT group

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/455965

Thesis Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth

Hendriks, Delilah; Artegiani, Benedetta; Margaritis, Thanasis et al. · 2024 · Utrecht University · DOI

Full title: Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth

Authors: Hendriks, Delilah; Artegiani, Benedetta; Margaritis, Thanasis; Zoutendijk, Iris; Chuva de Sousa Lopes, Susana; Clevers, Hans

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/453266

Thesis Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options

Boone, Ilja; Houtman, Evelyn; Tuerlings, Margo et al. · 2025 · Utrecht University · DOI

Full title: Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options

Authors: Boone, Ilja; Houtman, Evelyn; Tuerlings, Margo; van den Berg, Jim J.; Lehmann, Johannes; de Keizer, Peter L.J.; Nelissen, Rob G.H.H.; Meulenbelt, Ingrid

Year: 2025

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/460850

Thesis Species-specific primary cell cultures: a research tool in veterinary science

Sultan, Karim R.; H.P. · 2001 · Utrecht University · DOI

Full title: Species-specific primary cell cultures: a research tool in veterinary science

Authors: Sultan, Karim R.; H.P.

Year: 2001

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/7164

Thesis Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

Ooft, S. N.; Weeber, F.; Schipper, L. et al. · 2021 · Utrecht University · DOI

Full title: Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

Authors: Ooft, S. N.; Weeber, F.; Schipper, L.; Dijkstra, K. K.; McLean, C. M.; Kaing, S.; van de Haar, J.; Prevoo, W.; van Werkhoven, E.; Snaebjornsson, P.; Hoes, L. R.; Chalabi, M.; van der Velden, D.; van Leerdam, M.; Boot, H.; Grootscholten, C.; Huitema, A. D.R.; Bloemendal, H. J.; Cuppen, E.; Voest, E. E.

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/442778

Thesis Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

Brennand, Kristen J.; Marchetto, M. Carol; Benvenisty, Nissim et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

Authors: Brennand, Kristen J.; Marchetto, M. Carol; Benvenisty, Nissim; Brustle, Oliver; Ebert, Allison; Izpisua Belmonte, Juan Carlos; Kaykas, Ajamete; Lancaster, Madeline A.; Livesey, Frederick J.; McConnell, Michael J.; McKay, Ronald D.; Morrow, Eric M.; Muotri, Alysson R.; Panchision, David M.; Rubin, Lee L.; Sawa, Akira; Soldner, Frank; Song, Hongjun; Studer, Lorenz; Temple, Sally; Vaccarino, Flora M.; Wu, Jun; Vanderhaeghen, Pierre; Gage, Fred H.; Jaenisch, Rudolf

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/100810

Thesis Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Ardisasmita, Ibrahim; Joore, Indi; Levy, Natacha et al. · 2024 · Utrecht University · DOI

Full title: Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Authors: Ardisasmita, Ibrahim; Joore, Indi; Levy, Natacha; Myszczyszyn, A.; Marsee, Ary; Sinnige, Theo; Ruiter, J.; Ferdinandusse, Sacha; Dudaryeva, Oksana; Gruber, E.; Daive, V.; Levato, Riccardo; Spee, Bart; Verstegen, Monique Ma; van der Laan, L.J.W.; Nieuwenhuis , E.E.S.; Schene, Imre; Fuchs, Sabine

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/461147

Thesis High-throughput identification of small molecules that affect human embryonic vascular development

Vazão, Helena; Rosa, Susana; Barata, Tânia et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: High-throughput identification of small molecules that affect human embryonic vascular development

Authors: Vazão, Helena; Rosa, Susana; Barata, Tânia; Costa, Ricardo; Pitrez, Patrícia R.; Honório, Inês; de Vries, Margreet R.; Papatsenko, Dimitri; Benedito, Rui; Saris, Daniel; Quax, Paul H. A.; Pereira, Carlos F.; Mercader, Nadia; Fernandes, Hugo; Ferreira, Lino; Khademhosseini, Alireza

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/112205

Thesis A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

Kim, Choong; Kasuya, Junichi; Jeon, Jessie S et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

Authors: Kim, Choong; Kasuya, Junichi; Jeon, Jessie S; Chung, Seok; Kamm, Roger Dale

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/107403

Thesis Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration

Large, E. M.; Hughes, D. J.; Stokes, C. L. et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration

Authors: Large, E. M.; Hughes, D. J.; Stokes, C. L.; Yu, Jiajie; Cilfone, Nicholas A.; Sarkar, Ujjal; Tannenbaum, Steven R; Lauffenburger, Douglas A; Griffith, Linda G; Cirit, Murat; Wishnok, John S.

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/107165

Thesis Integration of systems biology with organs-on-chips to humanize therapeutic development

Clark, Amanda M.; Wells, Alan; Edington, Collin D et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Integration of systems biology with organs-on-chips to humanize therapeutic development

Authors: Clark, Amanda M.; Wells, Alan; Edington, Collin D; Cirit, Murat; Chen, Wen Li; Trumper, David L; Griffith, Linda G

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/115077

Thesis Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Tardiff, Daniel F.; Lindquist, Susan · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Authors: Tardiff, Daniel F.; Lindquist, Susan

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/101272

Thesis Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

Raja, Waseem K; Mungenast, Alison; Lin, Yuan-Ta et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

Authors: Raja, Waseem K; Mungenast, Alison; Lin, Yuan-Ta; Ko, Tak; Abdurrob, Fatema; Seo, Jinsoo; Tsai, Li-Huei

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/106315

Thesis Colorectal cancer models for novel drug discovery

Golovko, Daniel; Kedrin, Dmitriy; Yilmaz, Omer et al. · 2016 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Colorectal cancer models for novel drug discovery

Authors: Golovko, Daniel; Kedrin, Dmitriy; Yilmaz, Omer; Roper, Jatin

Year: 2016

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/105874

Thesis HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease

Vunjak-Novakovic, Gordana V; Bhatia, Sangeeta N; Chen, Christopher et al. · 2019 · Massachusetts Institute of Technology (MIT) · DOI

Full title: HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease

Authors: Vunjak-Novakovic, Gordana V; Bhatia, Sangeeta N; Chen, Christopher; Hirschi, Karen

Year: 2019

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/121236

Thesis Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification

Logan, David J; Shan, Jing; Bhatia, Sangeeta N et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification

Authors: Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Van Dyk, Anne Carpenter

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/110768

Thesis Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

Holmberg, Fredrik EO; Seidelin, Jakob B; Tong, Zhixiang et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

Authors: Holmberg, Fredrik EO; Seidelin, Jakob B; Tong, Zhixiang; Li, Yuan; Nielsen, Ole H; Yin, Xiaolei; Mead, Benjamin Elliott; Karp, Jeffrey Michael

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/114033

Thesis Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Zhang, Yu Shrike; Aleman, Julio; Shin, Su Ryon et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Authors: Zhang, Yu Shrike; Aleman, Julio; Shin, Su Ryon; Kilic, Tugba; Kim, Duckjin; Mousavi Shaegh, Seyed Ali; Massa, Solange; Riahi, Reza; Chae, Sukyoung; Hu, Ning; Avci, Huseyin; Silvestri, Antonia; Sanati Nezhad, Amir; Manbohi, Ahmad; De Ferrari, Fabio; Polini, Alessandro; Calzone, Giovanni; Shaikh, Noor; Alerasool, Parissa; Budina, Erica; Kang, Jian; Bhise, Nupura; Ribas, João; Pourmand, Adel; Skardal, Aleksander; Shupe, Thomas; Bishop, Colin E.; Dokmeci, Mehmet Remzi; Atala, Anthony; Zhang, Weijia; Khademhosseini, Ali

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/112226

Thesis Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System

Large, Emma; Hughes, David J.; Sarkar, Ujjal et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System

Authors: Large, Emma; Hughes, David J.; Sarkar, Ujjal; Ravindra, Kodihalli C.; Young, Carissa L.; Rivera-Burgos, Dinelia; Yu, Jiajie; Cirit, Murat; Wishnok, John S; Lauffenburger, Douglas A; Griffith, Linda G; Tannenbaum, Steven R

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/110981

Thesis Liver ‘organ on a chip’

Beckwitt, Colin H.; Clark, Amanda M.; Wheeler, Sarah et al. · 2019 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Liver ‘organ on a chip’

Authors: Beckwitt, Colin H.; Clark, Amanda M.; Wheeler, Sarah; Taylor, D. Lansing; Stolz, Donna B.; Wells, Alan; Griffith, Linda G

Year: 2019

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/120832

Thesis Engineering a perfusable 3D human liver platform from iPS cells

Schepers, Arnout; Li, Cheri Yingjie; Chhabra, Arnav et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Engineering a perfusable 3D human liver platform from iPS cells

Authors: Schepers, Arnout; Li, Cheri Yingjie; Chhabra, Arnav; Tschudy Seney, Benjamin; Bhatia, Sangeeta N

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/132166.2

Thesis Maximizing the Impact of Microphysiological Systems with in Vitro–in Vivo Translation

Stokes, Cynthia L.; Cirit, Murat · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Maximizing the Impact of Microphysiological Systems with in Vitro–in Vivo Translation

Authors: Stokes, Cynthia L.; Cirit, Murat

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116922

Thesis Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Bergmann, Sonja; Lawler, Sean E.; Qu, Yuan et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Authors: Bergmann, Sonja; Lawler, Sean E.; Qu, Yuan; Fadzen, Colin M.; Wolfe, Justin; Regan, Michael S.; Pentelute, Bradley L.; Agar, Nathalie Y. R.; Cho, Choi-Fong

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/123679

Thesis All models are wrong, but some organoids may be useful

Mead, Benjamin Elliott; Karp, Jeffrey Michael · 2019 · Massachusetts Institute of Technology (MIT) · DOI

Full title: All models are wrong, but some organoids may be useful

Authors: Mead, Benjamin Elliott; Karp, Jeffrey Michael

Year: 2019

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/122019

Thesis Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

Edington, Collin D; Chen, Wen Li; Geishecker, Emily R et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

Authors: Edington, Collin D; Chen, Wen Li; Geishecker, Emily R; Kassis, Timothy; Soenksen Martinez, Luis Ruben; Bhushan, Brij M; Maass, Christian Alexander; Tsamandouras, Nikolaos; Valdez Macias, Jorge Luis; Cook, Christi Dionne; Yu, Jiajie; Suter, Emily C; Shockley, Michael J; Velazquez, Jason G; Velazquez, Jeremy J.; Stockdale, Linda; Papps, Julia P; Lee, Iris; Vann, Nicholas W.; Contreras Gamboa, Mario e; LaBarge, Matthew E; Zhong, Zhe; Wang, Xin; Boyer, Laurie Ann; Lauffenburger, Douglas A; Carrier, Rebecca; Communal, Catherine; Tannenbaum, Steven R; Trumper, David L; Cirit, Murat; Griffith, Linda G

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/115178

Thesis Engineered Livers for Infectious Diseases

Gural, Nil; Mancio Silva, Liliana; He, Jiang et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Engineered Livers for Infectious Diseases

Authors: Gural, Nil; Mancio Silva, Liliana; He, Jiang; Bhatia, Sangeeta N

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/129529

Thesis Mathematical modelling to guide experimental protocols for in vitro cell culture

Hyndman, Lauren · 2021 · University of Glasgow · DOI

Full title: Mathematical modelling to guide experimental protocols for in vitro cell culture

Authors: Hyndman, Lauren

Year: 2021

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/82510/3/2021HyndmanPhD.pdf

Thesis Developing physiological 3D in vitro tissue models for rheumatology research

Khan, Aneesah M. · 2022 · University of Glasgow · DOI

Full title: Developing physiological 3D in vitro tissue models for rheumatology research

Authors: Khan, Aneesah M.

Year: 2022

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/82838/1/2022KhanAPhD.pdf

Thesis The utility of multimodal imaging platforms to identify antiviral inhibitors to influenza A virus infection

Orr, Lauren · 2025 · University of Glasgow · DOI

Full title: The utility of multimodal imaging platforms to identify antiviral inhibitors to influenza A virus infection

Authors: Orr, Lauren

Year: 2025

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/85335/1/2025OrrPhD.pdf

Thesis In vitro bronchial mucosa model using air-liquid interface culture on PLLA electrospun membrane

Salah, Nadira Abdi · 2019 · University of Glasgow · DOI

Full title: In vitro bronchial mucosa model using air-liquid interface culture on PLLA electrospun membrane

Authors: Salah, Nadira Abdi

Year: 2019

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/75122/3/2018SalahPhD.pdf

Thesis Development of molecular biology based in vitro toxicology tests fro industrial chemicals

Chen, Renjia · 2004 · UNSW Sydney · DOI

Full title: Development of molecular biology based in vitro toxicology tests fro industrial chemicals

Authors: Chen, Renjia

Year: 2004

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/63371

Thesis Three-dimensional organoid cell culture models for the study of liver injury

Collins, Scott · 2021 · UNSW Sydney · DOI

Full title: Three-dimensional organoid cell culture models for the study of liver injury

Authors: Collins, Scott

Year: 2021

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/100144

Thesis Using iPSC models to characterise the role of genetic and environmental effects in variable response to proarrhythmic drugs.

Xu, Michelle · 2024 · UNSW Sydney · DOI

Full title: Using iPSC models to characterise the role of genetic and environmental effects in variable response to proarrhythmic drugs.

Authors: Xu, Michelle

Year: 2024

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/102302

Thesis Molecular and Computational Platforms for Cancer Drug Screening and Precision Therapy

Matthews, Jonathan Martin · 2023 · University of Chicago - Knowledge@UChicago · DOI

Full title: Molecular and Computational Platforms for Cancer Drug Screening and Precision Therapy

Authors: Matthews, Jonathan Martin

Year: 2023

Venue: University of Chicago - Knowledge@UChicago

DOI: https://knowledge.uchicago.edu/record/6529/files/Matthews_uchicago_0330D_16945.pdf

Thesis A 3D in vitro model of the human gut-microbiome. A bioelectronics approach.

Moysidou, Chrysanthi-Maria · 2021 · University of Cambridge · DOI

Full title: A 3D in vitro model of the human gut-microbiome. A bioelectronics approach.

Authors: Moysidou, Chrysanthi-Maria

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/327423

Thesis Aortic “Disease-in-a-Dish”: Mechanistic Insights and Drug Development Using iPSC-Based Disease Modeling

Davaapil, Hongorzul; Shetty, Deeti K.; Sinha, Sanjay · 2020 · University of Cambridge · DOI

Full title: Aortic “Disease-in-a-Dish”: Mechanistic Insights and Drug Development Using iPSC-Based Disease Modeling

Authors: Davaapil, Hongorzul; Shetty, Deeti K.; Sinha, Sanjay

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/312759

Thesis In vitro models for investigating itch

Smith, Ewan; Mießner, Hendrik; Judith, Seidel · 2022 · University of Cambridge · DOI

Full title: In vitro models for investigating itch

Authors: Smith, Ewan; Mießner, Hendrik; Judith, Seidel

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/341948

Thesis Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis

Orbach, Sophia Michelle · 2019 · Virginia Tech - VTechWorks · DOI

Full title: Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis

Authors: Orbach, Sophia Michelle

Year: 2019

Venue: Virginia Tech - VTechWorks

DOI: http://hdl.handle.net/10919/93313

Thesis Developing bioelectronic sensors for 3D in vitro models at the air liquid interface: Innovative technology for biomedical and respiratory research.

Barron, Sarah · 2024 · University of Cambridge · DOI

Full title: Developing bioelectronic sensors for 3D in vitro models at the air liquid interface: Innovative technology for biomedical and respiratory research.

Authors: Barron, Sarah

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/363508

Thesis Human Liver Organoids as models for investigating drug-induced liver injury

Kaluthantrige Don, Mewanthi Flaminia · 2022 · University of Cambridge · DOI

Full title: Human Liver Organoids as models for investigating drug-induced liver injury

Authors: Kaluthantrige Don, Mewanthi Flaminia

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/335284

Thesis Development and Characterisation of a Vessel-On-a-Chip Model of Inflammation and Inflammatory Haemostasis

Riddle, Rebecca · 2023 · University of Cambridge · DOI

Full title: Development and Characterisation of a Vessel-On-a-Chip Model of Inflammation and Inflammatory Haemostasis

Authors: Riddle, Rebecca

Year: 2023

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/361577

Thesis 3D Cell Culture in Microgels: A Novel Screening Platform for Disease Modelling and Drug Testing

Maring, Alisa · 2025 · University of Cambridge · DOI

Full title: 3D Cell Culture in Microgels: A Novel Screening Platform for Disease Modelling and Drug Testing

Authors: Maring, Alisa

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/388923

Thesis hiPSC-Derived Cerebral Small Vessel Disease Models

Al-Thani, Maha · 2024 · University of Cambridge · DOI

Full title: hiPSC-Derived Cerebral Small Vessel Disease Models

Authors: Al-Thani, Maha

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/366502

Thesis Three-Dimensional Cell Cultures as a Research Platform in Lung Diseases and COVID-19

Ribeiro-Paes, João Tadeu · 2021 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Three-Dimensional Cell Cultures as a Research Platform in Lung Diseases and COVID-19

Authors: Ribeiro-Paes, João Tadeu

Year: 2021

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1007/s13770-021-00348-x

Thesis Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19

Pereira, Lygia da Veiga · 2020 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19

Authors: Pereira, Lygia da Veiga

Year: 2020

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1590/1678-4685-gmb-2020-0198

Thesis Optimizing in Vitro Motility Assays for High-Throughput Analysis of Actin-Myosin Dynamics and Drug Screening

Presley, Noah · 2025 · University of Guelph · DOI

Full title: Optimizing in Vitro Motility Assays for High-Throughput Analysis of Actin-Myosin Dynamics and Drug Screening

Authors: Presley, Noah

Year: 2025

Venue: University of Guelph

DOI: https://hdl.handle.net/10214/29358

Thesis High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

Leuchowius, Karl-Johan · 2010 · Uppsala University · DOI

Full title: High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

Authors: Leuchowius, Karl-Johan

Year: 2010

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119530

Thesis Visualization of Protein Activity Status in situ Using Proximity Ligation Assays

Jarvius, Malin · 2010 · Uppsala University · DOI

Full title: Visualization of Protein Activity Status in situ Using Proximity Ligation Assays

Authors: Jarvius, Malin

Year: 2010

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131934

Thesis High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities

Senkowski, Wojciech · 2017 · Uppsala University · DOI

Full title: High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities

Authors: Senkowski, Wojciech

Year: 2017

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-320598

Thesis Molecular Approaches to Explore Drug-Target Interactions

Al-Amin, Abdullah · 2019 · Uppsala University · DOI

Full title: Molecular Approaches to Explore Drug-Target Interactions

Authors: Al-Amin, Abdullah

Year: 2019

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-374329

Thesis Development of Human Pancreatic Ductal Epithelial Cells as a model of Cystic Fibrosis Pancreatic Disease

Malik, Sarah · 2024 · University of Washington - ResearchWorks · DOI

Full title: Development of Human Pancreatic Ductal Epithelial Cells as a model of Cystic Fibrosis Pancreatic Disease

Authors: Malik, Sarah

Year: 2024

Venue: University of Washington - ResearchWorks

DOI: https://hdl.handle.net/1773/52146

Thesis Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier

Jelinsky, Scott A; Derksen, Merel; Bauman, Eric et al. · 2023 · Utrecht University · DOI

Full title: Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier

Authors: Jelinsky, Scott A; Derksen, Merel; Bauman, Eric; Verissimo, Carla S; van Dooremalen, Wies T M; Roos, Jamie Lee; Higuera Barón, Celia; Caballero-Franco, Celia; Johnson, Bryce G; Rooks, Michelle G; Pott, Johanna; Oldenburg, Bas; Vries, Robert G J; Boj, Sylvia F; Kasaian, Marion T; Pourfarzad, Farzin; Rosadini, Charles V

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447481

Thesis Narrowing the translational gap in metabolic dysfunction-associated steatotic liver disease (MASLD) drug development

Aurino Kemas (18658303) · 2025 · Karolinska Institutet · DOI

Full title: Narrowing the translational gap in metabolic dysfunction-associated steatotic liver disease (MASLD) drug development

Authors: Aurino Kemas (18658303)

Year: 2025

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/29921738

Thesis An evaluation of in vitro models for the assessment of mitochondrial toxicity within Drug Induced Liver Injury (DILI)

Douglas, O · 2017 · University of Liverpool · DOI

Full title: An evaluation of in vitro models for the assessment of mitochondrial toxicity within Drug Induced Liver Injury (DILI)

Authors: Douglas, O

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3012327/1/200916787_Mar2017.pdf

Thesis Development and Exploration of New Automated Tools to Accelerate Research on Tissue and Tumor Model Systems

Schuster, Brooke Elizabeth · 2022 · University of Chicago - Knowledge@UChicago · DOI

Full title: Development and Exploration of New Automated Tools to Accelerate Research on Tissue and Tumor Model Systems

Authors: Schuster, Brooke Elizabeth

Year: 2022

Venue: University of Chicago - Knowledge@UChicago

DOI: https://knowledge.uchicago.edu/record/3653/files/Schuster_uchicago_0330D_16165.pdf

Thesis Liver organoids: from basic research to therapeutic applications.

Prior, Nicole; Inacio, Patricia; Huch, Meritxell · 2019 · University of Cambridge · DOI

Full title: Liver organoids: from basic research to therapeutic applications.

Authors: Prior, Nicole; Inacio, Patricia; Huch, Meritxell

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/294664

Patent us-2023304996-a1

· 2023

Full title: us-2023304996-a1

Year: 2023

Patent us-2023356216-a1

· 2023

Full title: us-2023356216-a1

Year: 2023

Patent us-2023374446-a1

· 2023

Full title: us-2023374446-a1

Year: 2023

Patent us-2023383264-a1

· 2023

Full title: us-2023383264-a1

Year: 2023

Patent us-2023368374-a1

· 2023

Full title: us-2023368374-a1

Year: 2023

Patent us-2023364528-a1

· 2023

Full title: us-2023364528-a1

Year: 2023

Patent us-2024010961-a1

· 2024

Full title: us-2024010961-a1

Year: 2024

Patent us-2024010987-a1

· 2024

Full title: us-2024010987-a1

Year: 2024

Patent us-2024026268-a1

· 2024

Full title: us-2024026268-a1

Year: 2024

Patent us-2024010993-a1

· 2024

Full title: us-2024010993-a1

Year: 2024

Patent us-2024011973-a1

· 2024

Full title: us-2024011973-a1

Year: 2024

Patent us-2024024873-a1

· 2024

Full title: us-2024024873-a1

Year: 2024

Patent us-2024036033-a1

· 2024

Full title: us-2024036033-a1

Year: 2024

Patent us-2024065237-a1

· 2024

Full title: us-2024065237-a1

Year: 2024

Patent us-2024117431-a1

· 2024

Full title: us-2024117431-a1

Year: 2024

Patent us-2024043808-a1

· 2024

Full title: us-2024043808-a1

Year: 2024

Patent us-2024032528-a1

· 2024

Full title: us-2024032528-a1

Year: 2024

Patent us-2024117320-a1

· 2024

Full title: us-2024117320-a1

Year: 2024

Patent us-2024093136-a1

· 2024

Full title: us-2024093136-a1

Year: 2024

Patent us-2024182863-a1

· 2024

Full title: us-2024182863-a1

Year: 2024

Patent us-2024093154-a1

· 2024

Full title: us-2024093154-a1

Year: 2024

Patent us-2024133872-a1

· 2024

Full title: us-2024133872-a1

Year: 2024

Patent us-2024093236-a1

· 2024

Full title: us-2024093236-a1

Year: 2024

Patent us-2024076593-a1

· 2024

Full title: us-2024076593-a1

Year: 2024

Patent us-2024115620-a1

· 2024

Full title: us-2024115620-a1

Year: 2024

Patent us-2024125767-a1

· 2024

Full title: us-2024125767-a1

Year: 2024

Patent us-2024099278-a1

· 2024

Full title: us-2024099278-a1

Year: 2024

Patent us-2024228927-a1

· 2024

Full title: us-2024228927-a1

Year: 2024

Patent us-2024133873-a1

· 2024

Full title: us-2024133873-a1

Year: 2024

Patent us-2024132849-a1

· 2024

Full title: us-2024132849-a1

Year: 2024

Patent us-2024198337-a1

· 2024

Full title: us-2024198337-a1

Year: 2024

Patent us-2024183843-a1

· 2024

Full title: us-2024183843-a1

Year: 2024

Patent us-2024118267-a1

· 2024

Full title: us-2024118267-a1

Year: 2024

Patent us-2024142438-a1

· 2024

Full title: us-2024142438-a1

Year: 2024

Patent us-2024158728-a1

· 2024

Full title: us-2024158728-a1

Year: 2024

Patent us-2024254449-a1

· 2024

Full title: us-2024254449-a1

Year: 2024

Patent us-2024271066-a1

· 2024

Full title: us-2024271066-a1

Year: 2024

Patent us-2024182868-a1

· 2024

Full title: us-2024182868-a1

Year: 2024

Patent us-2024301358-a1

· 2024

Full title: us-2024301358-a1

Year: 2024

Patent us-2024210384-a1

· 2024

Full title: us-2024210384-a1

Year: 2024

Patent us-2024218321-a1

· 2024

Full title: us-2024218321-a1

Year: 2024

Patent us-2024228929-a1

· 2024

Full title: us-2024228929-a1

Year: 2024

Patent us-2024228973-a9

· 2024

Full title: us-2024228973-a9

Year: 2024

Patent us-2024360400-a1

· 2024

Full title: us-2024360400-a1

Year: 2024

Patent us-2024302352-a1

· 2024

Full title: us-2024302352-a1

Year: 2024

Patent us-2024368556-a1

· 2024

Full title: us-2024368556-a1

Year: 2024

Patent us-2024230629-a9

· 2024

Full title: us-2024230629-a9

Year: 2024

Patent us-2024309331-a1

· 2024

Full title: us-2024309331-a1

Year: 2024

Patent us-2024392249-a1

· 2024

Full title: us-2024392249-a1

Year: 2024

Patent us-2024307591-a1

· 2024

Full title: us-2024307591-a1

Year: 2024

Patent us-2024320992-a1

· 2024

Full title: us-2024320992-a1

Year: 2024

Patent us-2024400997-a1

· 2024

Full title: us-2024400997-a1

Year: 2024

Patent us-2025017977-a1

· 2025

Full title: us-2025017977-a1

Year: 2025

Patent us-2025002862-a1

· 2025

Full title: us-2025002862-a1

Year: 2025

Patent us-2025084356-a1

· 2025

Full title: us-2025084356-a1

Year: 2025

Patent us-2025066736-a1

· 2025

Full title: us-2025066736-a1

Year: 2025

Patent us-2024392223-a1

· 2024

Full title: us-2024392223-a1

Year: 2024

Patent us-2024417661-a1

· 2024

Full title: us-2024417661-a1

Year: 2024

Patent us-2025067728-a1

· 2025

Full title: us-2025067728-a1

Year: 2025

Patent us-2025064051-a1

· 2025

Full title: us-2025064051-a1

Year: 2025

Patent us-2025051732-a1

· 2025

Full title: us-2025051732-a1

Year: 2025

Patent us-2025164464-a1

· 2025

Full title: us-2025164464-a1

Year: 2025

Patent us-2025129338-a1

· 2025

Full title: us-2025129338-a1

Year: 2025

Patent us-2025172543-a1

· 2025

Full title: us-2025172543-a1

Year: 2025

Patent us-2025120372-a1

· 2025

Full title: us-2025120372-a1

Year: 2025

Patent us-2025057128-a1

· 2025

Full title: us-2025057128-a1

Year: 2025

Patent us-2025066703-a1

· 2025

Full title: us-2025066703-a1

Year: 2025

Patent us-2025228899-a1

· 2025

Full title: us-2025228899-a1

Year: 2025

Patent us-2025207101-a1

· 2025

Full title: us-2025207101-a1

Year: 2025

Patent us-2025248377-a1

· 2025

Full title: us-2025248377-a1

Year: 2025

Patent us-2025235802-a1

· 2025

Full title: us-2025235802-a1

Year: 2025

Patent us-2025136910-a1

· 2025

Full title: us-2025136910-a1

Year: 2025

Patent us-2025179436-a1

· 2025

Full title: us-2025179436-a1

Year: 2025

Patent us-2025145962-a1

· 2025

Full title: us-2025145962-a1

Year: 2025

Patent us-2025257325-a1

· 2025

Full title: us-2025257325-a1

Year: 2025

Patent us-2025230390-a1

· 2025

Full title: us-2025230390-a1

Year: 2025

Patent us-2025250521-a1

· 2025

Full title: us-2025250521-a1

Year: 2025

Patent us-2025304896-a1

· 2025

Full title: us-2025304896-a1

Year: 2025

Patent us-2025297225-a1

· 2025

Full title: us-2025297225-a1

Year: 2025

Patent us-2025304912-a1

· 2025

Full title: us-2025304912-a1

Year: 2025

Patent us-2025304893-a1

· 2025

Full title: us-2025304893-a1

Year: 2025

Patent us-2025222453-a1

· 2025

Full title: us-2025222453-a1

Year: 2025

Patent us-2025212854-a1

· 2025

Full title: us-2025212854-a1

Year: 2025

Patent us-5565353-a

· 1996

Full title: us-5565353-a

Year: 1996

Patent us-5270192-a

· 1993

Full title: us-5270192-a

Year: 1993

Patent us-2025313807-a1

· 2025

Full title: us-2025313807-a1

Year: 2025

Patent us-10030219-b2

· 2018

Full title: us-10030219-b2

Year: 2018

Patent us-10087422-b2

· 2018

Full title: us-10087422-b2

Year: 2018

Patent us-10087408-b2

· 2018

Full title: us-10087408-b2

Year: 2018

Patent us-10184113-b2

· 2019

Full title: us-10184113-b2

Year: 2019

Patent us-10184102-b2

· 2019

Full title: us-10184102-b2

Year: 2019

Patent us-10254274-b2

· 2019

Full title: us-10254274-b2

Year: 2019

Patent us-10392595-b2

· 2019

Full title: us-10392595-b2

Year: 2019

Patent us-10184109-b2

· 2019

Full title: us-10184109-b2

Year: 2019

Patent us-10473646-b2

· 2019

Full title: us-10473646-b2

Year: 2019

Patent us-10233416-b2

· 2019

Full title: us-10233416-b2

Year: 2019

Patent us-10266806-b2

· 2019

Full title: us-10266806-b2

Year: 2019

Patent us-10273441-b2

· 2019

Full title: us-10273441-b2

Year: 2019

Patent us-10314295-b2

· 2019

Full title: us-10314295-b2

Year: 2019

Patent us-10213525-b2

· 2019

Full title: us-10213525-b2

Year: 2019

Patent us-10336987-b2

· 2019

Full title: us-10336987-b2

Year: 2019

Patent us-10696949-b2

· 2020

Full title: us-10696949-b2

Year: 2020

Patent us-10488390-b2

· 2019

Full title: us-10488390-b2

Year: 2019

Patent us-10421936-b2

· 2019

Full title: us-10421936-b2

Year: 2019

Patent us-10317395-b1

· 2019

Full title: us-10317395-b1

Year: 2019

Patent us-10519410-b2

· 2019

Full title: us-10519410-b2

Year: 2019

Patent us-10689608-b2

· 2020

Full title: us-10689608-b2

Year: 2020

Patent us-10465155-b2

· 2019

Full title: us-10465155-b2

Year: 2019

Patent us-10954489-b2

· 2021

Full title: us-10954489-b2

Year: 2021

Patent us-10632305-b2

· 2020

Full title: us-10632305-b2

Year: 2020

Patent us-10704018-b2

· 2020

Full title: us-10704018-b2

Year: 2020

Patent us-10683483-b2

· 2020

Full title: us-10683483-b2

Year: 2020

Patent us-10526578-b2

· 2020

Full title: us-10526578-b2

Year: 2020

Patent us-10597623-b2

· 2020

Full title: us-10597623-b2

Year: 2020

Patent us-10828638-b2

· 2020

Full title: us-10828638-b2

Year: 2020

Patent us-10976308-b2

· 2021

Full title: us-10976308-b2

Year: 2021

Patent us-10815460-b2

· 2020

Full title: us-10815460-b2

Year: 2020

Patent us-10785968-b2

· 2020

Full title: us-10785968-b2

Year: 2020

Patent us-10767164-b2

· 2020

Full title: us-10767164-b2

Year: 2020

Patent us-10732174-b2

· 2020

Full title: us-10732174-b2

Year: 2020

Patent us-10738270-b2

· 2020

Full title: us-10738270-b2

Year: 2020

Patent us-10913924-b2

· 2021

Full title: us-10913924-b2

Year: 2021

Patent us-11001795-b2

· 2021

Full title: us-11001795-b2

Year: 2021

Patent us-10988721-b2

· 2021

Full title: us-10988721-b2

Year: 2021

Patent us-10869465-b2

· 2020

Full title: us-10869465-b2

Year: 2020

Patent us-10988722-b2

· 2021

Full title: us-10988722-b2

Year: 2021

Patent us-10018620-b2

· 2018

Full title: us-10018620-b2

Year: 2018

Patent us-11124774-b2

· 2021

Full title: us-11124774-b2

Year: 2021

Patent us-11142734-b2

· 2021

Full title: us-11142734-b2

Year: 2021

Patent us-11041145-b2

· 2021

Full title: us-11041145-b2

Year: 2021

Patent us-11059041-b2

· 2021

Full title: us-11059041-b2

Year: 2021

Patent us-11072772-b2

· 2021

Full title: us-11072772-b2

Year: 2021

Patent us-2016053231-a1

· 2016

Full title: us-2016053231-a1

Year: 2016

Patent us-2016083681-a1

· 2016

Full title: us-2016083681-a1

Year: 2016

Patent us-2015344828-a1

· 2015

Full title: us-2015344828-a1

Year: 2015

Patent us-2016017288-a1

· 2016

Full title: us-2016017288-a1

Year: 2016

Patent us-2015283269-a1

· 2015

Full title: us-2015283269-a1

Year: 2015

Patent us-2016137986-a1

· 2016

Full title: us-2016137986-a1

Year: 2016

Patent us-2016272946-a1

· 2016

Full title: us-2016272946-a1

Year: 2016

Patent us-2016131636-a1

· 2016

Full title: us-2016131636-a1

Year: 2016

Patent us-2015301027-a1

· 2015

Full title: us-2015301027-a1

Year: 2015

Patent us-2016130551-a1

· 2016

Full title: us-2016130551-a1

Year: 2016

Patent us-2015282460-a1

· 2015

Full title: us-2015282460-a1

Year: 2015

Patent us-2016339429-a1

· 2016

Full title: us-2016339429-a1

Year: 2016

Patent us-2016298087-a1

· 2016

Full title: us-2016298087-a1

Year: 2016

Patent us-2016340632-a1

· 2016

Full title: us-2016340632-a1

Year: 2016

Patent us-2016145570-a1

· 2016

Full title: us-2016145570-a1

Year: 2016

Patent us-2016348067-a1

· 2016

Full title: us-2016348067-a1

Year: 2016

Patent us-2017055522-a1

· 2017

Full title: us-2017055522-a1

Year: 2017

Patent us-2016363584-a1

· 2016

Full title: us-2016363584-a1

Year: 2016

Patent us-2017009194-a1

· 2017

Full title: us-2017009194-a1

Year: 2017

Patent us-2016366862-a1

· 2016

Full title: us-2016366862-a1

Year: 2016

Patent us-2017055504-a1

· 2017

Full title: us-2017055504-a1

Year: 2017

Patent us-2016130543-a1

· 2016

Full title: us-2016130543-a1

Year: 2016

Patent us-2017158997-a1

· 2017

Full title: us-2017158997-a1

Year: 2017

Patent us-2017145386-a1

· 2017

Full title: us-2017145386-a1

Year: 2017

Patent us-2017211029-a1

· 2017

Full title: us-2017211029-a1

Year: 2017

Patent us-2018015126-a1

· 2018

Full title: us-2018015126-a1

Year: 2018

Patent us-2017290665-a1

· 2017

Full title: us-2017290665-a1

Year: 2017

Patent us-2017370908-a1

· 2017

Full title: us-2017370908-a1

Year: 2017

Patent us-2017058257-a1

· 2017

Full title: us-2017058257-a1

Year: 2017

Patent us-2017269066-a1

· 2017

Full title: us-2017269066-a1

Year: 2017

Patent us-2017058248-a1

· 2017

Full title: us-2017058248-a1

Year: 2017

Patent us-2018042970-a1

· 2018

Full title: us-2018042970-a1

Year: 2018

Patent us-2018024121-a1

· 2018

Full title: us-2018024121-a1

Year: 2018

Patent us-2018064527-a1

· 2018

Full title: us-2018064527-a1

Year: 2018

Patent us-2017198254-a1

· 2017

Full title: us-2017198254-a1

Year: 2017

Patent us-2018049413-a1

· 2018

Full title: us-2018049413-a1

Year: 2018

Patent us-2018163166-a1

· 2018

Full title: us-2018163166-a1

Year: 2018

Patent us-2018147242-a1

· 2018

Full title: us-2018147242-a1

Year: 2018

Patent us-2018185844-a1

· 2018

Full title: us-2018185844-a1

Year: 2018

Patent us-2018216063-a1

· 2018

Full title: us-2018216063-a1

Year: 2018

Patent us-2018172668-a1

· 2018

Full title: us-2018172668-a1

Year: 2018

Patent us-2018223253-a1

· 2018

Full title: us-2018223253-a1

Year: 2018

Patent us-2018135011-a1

· 2018

Full title: us-2018135011-a1

Year: 2018

Patent us-2018224432-a1

· 2018

Full title: us-2018224432-a1

Year: 2018

Patent us-2018230417-a1

· 2018

Full title: us-2018230417-a1

Year: 2018

Patent us-2018280971-a1

· 2018

Full title: us-2018280971-a1

Year: 2018

Patent us-2018237861-a1

· 2018

Full title: us-2018237861-a1

Year: 2018

Patent us-2018291350-a1

· 2018

Full title: us-2018291350-a1

Year: 2018

Patent us-2018305669-a1

· 2018

Full title: us-2018305669-a1

Year: 2018

Patent us-2018355298-a1

· 2018

Full title: us-2018355298-a1

Year: 2018

Patent us-2018321224-a1

· 2018

Full title: us-2018321224-a1

Year: 2018

Patent us-2018282699-a1

· 2018

Full title: us-2018282699-a1

Year: 2018

Patent us-2018334646-a1

· 2018

Full title: us-2018334646-a1

Year: 2018

Patent us-2019048315-a1

· 2019

Full title: us-2019048315-a1

Year: 2019

Patent us-2019018002-a1

· 2019

Full title: us-2019018002-a1

Year: 2019

Patent us-2018245050-a1

· 2018

Full title: us-2018245050-a1

Year: 2018

Patent us-2019031992-a1

· 2019

Full title: us-2019031992-a1

Year: 2019

Patent us-2018369423-a1

· 2018

Full title: us-2018369423-a1

Year: 2018

Patent us-2019119619-a1

· 2019

Full title: us-2019119619-a1

Year: 2019

Patent us-2019032021-a1

· 2019

Full title: us-2019032021-a1

Year: 2019

Patent us-2019040349-a1

· 2019

Full title: us-2019040349-a1

Year: 2019

Patent us-2018327701-a1

· 2018

Full title: us-2018327701-a1

Year: 2018

Patent us-2018327702-a1

· 2018

Full title: us-2018327702-a1

Year: 2018

Patent us-2019062684-a1

· 2019

Full title: us-2019062684-a1

Year: 2019

Patent us-2019119626-a1

· 2019

Full title: us-2019119626-a1

Year: 2019

Patent us-2019093077-a1

· 2019

Full title: us-2019093077-a1

Year: 2019

Patent us-2019071638-a1

· 2019

Full title: us-2019071638-a1

Year: 2019

Patent us-2019119647-a1

· 2019

Full title: us-2019119647-a1

Year: 2019

Patent us-2019218540-a1

· 2019

Full title: us-2019218540-a1

Year: 2019

Patent us-2019112566-a1

· 2019

Full title: us-2019112566-a1

Year: 2019

Patent us-2019216062-a1

· 2019

Full title: us-2019216062-a1

Year: 2019

Patent us-2019076842-a1

· 2019

Full title: us-2019076842-a1

Year: 2019

Patent us-2019218588-a1

· 2019

Full title: us-2019218588-a1

Year: 2019

Patent us-2019232277-a1

· 2019

Full title: us-2019232277-a1

Year: 2019

Patent us-2019249215-a1

· 2019

Full title: us-2019249215-a1

Year: 2019

Patent us-2019153395-a1

· 2019

Full title: us-2019153395-a1

Year: 2019

Patent us-2019177678-a1

· 2019

Full title: us-2019177678-a1

Year: 2019

Patent us-2019169557-a1

· 2019

Full title: us-2019169557-a1

Year: 2019

Patent us-2019233787-a1

· 2019

Full title: us-2019233787-a1

Year: 2019

Patent us-2019284535-a1

· 2019

Full title: us-2019284535-a1

Year: 2019

Patent us-2019300851-a1

· 2019

Full title: us-2019300851-a1

Year: 2019

Patent us-2019330583-a1

· 2019

Full title: us-2019330583-a1

Year: 2019

Patent us-2019339257-a1

· 2019

Full title: us-2019339257-a1

Year: 2019

Patent us-2019285619-a1

· 2019

Full title: us-2019285619-a1

Year: 2019

Patent us-2019292518-a1

· 2019

Full title: us-2019292518-a1

Year: 2019

Patent us-2019289834-a1

· 2019

Full title: us-2019289834-a1

Year: 2019

Patent us-2019276799-a1

· 2019

Full title: us-2019276799-a1

Year: 2019

Patent us-2019331662-a1

· 2019

Full title: us-2019331662-a1

Year: 2019

Patent us-2019298775-a1

· 2019

Full title: us-2019298775-a1

Year: 2019

Patent us-2019316093-a1

· 2019

Full title: us-2019316093-a1

Year: 2019

Patent us-2019365951-a1

· 2019

Full title: us-2019365951-a1

Year: 2019

Patent us-2020010806-a1

· 2020

Full title: us-2020010806-a1

Year: 2020

Patent us-2020015462-a1

· 2020

Full title: us-2020015462-a1

Year: 2020

Patent us-2019320629-a1

· 2019

Full title: us-2019320629-a1

Year: 2019

Patent us-2019376013-a1

· 2019

Full title: us-2019376013-a1

Year: 2019

Patent us-2019382701-a1

· 2019

Full title: us-2019382701-a1

Year: 2019

Patent us-2020132670-a1

· 2020

Full title: us-2020132670-a1

Year: 2020

Patent us-2020017811-a1

· 2020

Full title: us-2020017811-a1

Year: 2020

Patent us-2019367860-a1

· 2019

Full title: us-2019367860-a1

Year: 2019

Patent us-2020048601-a1

· 2020

Full title: us-2020048601-a1

Year: 2020

Patent us-2020018747-a1

· 2020

Full title: us-2020018747-a1

Year: 2020

Patent us-2020115682-a1

· 2020

Full title: us-2020115682-a1

Year: 2020

Patent us-2020071674-a1

· 2020

Full title: us-2020071674-a1

Year: 2020

Patent us-2020190455-a1

· 2020

Full title: us-2020190455-a1

Year: 2020

Patent us-2020140801-a1

· 2020

Full title: us-2020140801-a1

Year: 2020

Patent us-2020121464-a1

· 2020

Full title: us-2020121464-a1

Year: 2020

Patent us-2020181580-a1

· 2020

Full title: us-2020181580-a1

Year: 2020

Patent us-2020095525-a1

· 2020

Full title: us-2020095525-a1

Year: 2020

Patent us-2020063081-a1

· 2020

Full title: us-2020063081-a1

Year: 2020

Patent us-2020188444-a1

· 2020

Full title: us-2020188444-a1

Year: 2020

Patent us-2020239843-a1

· 2020

Full title: us-2020239843-a1

Year: 2020

Patent us-2020140808-a1

· 2020

Full title: us-2020140808-a1

Year: 2020

Patent us-2020224136-a1

· 2020

Full title: us-2020224136-a1

Year: 2020

Patent us-2020190456-a1

· 2020

Full title: us-2020190456-a1

Year: 2020

Patent us-2020208090-a1

· 2020

Full title: us-2020208090-a1

Year: 2020

Patent us-2020224171-a1

· 2020

Full title: us-2020224171-a1

Year: 2020

Patent us-2020325431-a1

· 2020

Full title: us-2020325431-a1

Year: 2020

Patent us-2020283732-a1

· 2020

Full title: us-2020283732-a1

Year: 2020

Patent us-2020277568-a1

· 2020

Full title: us-2020277568-a1

Year: 2020

Patent us-2020239851-a1

· 2020

Full title: us-2020239851-a1

Year: 2020

Patent us-2020216791-a1

· 2020

Full title: us-2020216791-a1

Year: 2020

Patent us-2020339956-a1

· 2020

Full title: us-2020339956-a1

Year: 2020

Patent us-2020199537-a1

· 2020

Full title: us-2020199537-a1

Year: 2020

Patent us-2020115680-a1

· 2020

Full title: us-2020115680-a1

Year: 2020

Patent us-2020354663-a1

· 2020

Full title: us-2020354663-a1

Year: 2020

Patent us-2020270582-a1

· 2020

Full title: us-2020270582-a1

Year: 2020

Patent us-2020377860-a1

· 2020

Full title: us-2020377860-a1

Year: 2020

Patent us-2020339955-a1

· 2020

Full title: us-2020339955-a1

Year: 2020

Patent us-2020369996-a1

· 2020

Full title: us-2020369996-a1

Year: 2020

Patent us-2021018492-a1

· 2021

Full title: us-2021018492-a1

Year: 2021

Patent us-2020385661-a1

· 2020

Full title: us-2020385661-a1

Year: 2020

Patent us-2020390825-a1

· 2020

Full title: us-2020390825-a1

Year: 2020

Patent us-2020370005-a1

· 2020

Full title: us-2020370005-a1

Year: 2020

Patent us-2020352918-a1

· 2020

Full title: us-2020352918-a1

Year: 2020

Patent us-2020378952-a1

· 2020

Full title: us-2020378952-a1

Year: 2020

Patent us-2020378956-a1

· 2020

Full title: us-2020378956-a1

Year: 2020

Patent us-2020377863-a1

· 2020

Full title: us-2020377863-a1

Year: 2020

Patent us-2021040428-a1

· 2021

Full title: us-2021040428-a1

Year: 2021

Patent us-2021047617-a1

· 2021

Full title: us-2021047617-a1

Year: 2021

Patent us-2021095256-a1

· 2021

Full title: us-2021095256-a1

Year: 2021

Patent us-2020399611-a1

· 2020

Full title: us-2020399611-a1

Year: 2020

Patent us-2021054321-a1

· 2021

Full title: us-2021054321-a1

Year: 2021

Patent us-2021100228-a1

· 2021

Full title: us-2021100228-a1

Year: 2021

Patent us-2021031197-a1

· 2021

Full title: us-2021031197-a1

Year: 2021

Patent us-2021062129-a1

· 2021

Full title: us-2021062129-a1

Year: 2021

Patent us-2021055283-a1

· 2021

Full title: us-2021055283-a1

Year: 2021

Patent us-2021179992-a1

· 2021

Full title: us-2021179992-a1

Year: 2021

Patent us-2021054324-a1

· 2021

Full title: us-2021054324-a1

Year: 2021

Patent us-2021108178-a1

· 2021

Full title: us-2021108178-a1

Year: 2021

Patent us-2021130774-a1

· 2021

Full title: us-2021130774-a1

Year: 2021

Patent us-2021189346-a1

· 2021

Full title: us-2021189346-a1

Year: 2021

Patent us-2021127647-a1

· 2021

Full title: us-2021127647-a1

Year: 2021

Patent us-2021115406-a1

· 2021

Full title: us-2021115406-a1

Year: 2021

Patent us-2021260137-a1

· 2021

Full title: us-2021260137-a1

Year: 2021

Patent us-2021269774-a1

· 2021

Full title: us-2021269774-a1

Year: 2021

Patent us-2021254012-a1

· 2021

Full title: us-2021254012-a1

Year: 2021

Patent us-2021222131-a1

· 2021

Full title: us-2021222131-a1

Year: 2021

Patent us-2021322642-a1

· 2021

Full title: us-2021322642-a1

Year: 2021

Patent us-2021292714-a1

· 2021

Full title: us-2021292714-a1

Year: 2021

Patent us-2021171889-a1

· 2021

Full title: us-2021171889-a1

Year: 2021

Patent us-2021229097-a1

· 2021

Full title: us-2021229097-a1

Year: 2021

Patent us-2021277349-a1

· 2021

Full title: us-2021277349-a1

Year: 2021

Patent us-2021252509-a1

· 2021

Full title: us-2021252509-a1

Year: 2021

Patent us-2021341462-a1

· 2021

Full title: us-2021341462-a1

Year: 2021

Patent us-5491284-a

· 1996

Full title: us-5491284-a

Year: 1996

Patent us-5112757-a

· 1992

Full title: us-5112757-a

Year: 1992

Patent us-6008047-a

· 1999

Full title: us-6008047-a

Year: 1999

Patent us-2024158755-a1

· 2024

Full title: us-2024158755-a1

Year: 2024

Patent us-6228595-b1

· 2001

Full title: us-6228595-b1

Year: 2001

Patent us-5849995-a

· 1998

Full title: us-5849995-a

Year: 1998

Patent us-6284239-b1

· 2001

Full title: us-6284239-b1

Year: 2001

Patent us-5625128-a

· 1997

Full title: us-5625128-a

Year: 1997

Patent us-5986170-a

· 1999

Full title: us-5986170-a

Year: 1999

Patent us-5667766-a

· 1997

Full title: us-5667766-a

Year: 1997

Patent us-6780580-b2

· 2004

Full title: us-6780580-b2

Year: 2004

Patent us-6197575-b1

· 2001

Full title: us-6197575-b1

Year: 2001

Patent us-7622298-b2

· 2009

Full title: us-7622298-b2

Year: 2009

Patent us-6759245-b1

· 2004

Full title: us-6759245-b1

Year: 2004

Patent us-6949691-b2

· 2005

Full title: us-6949691-b2

Year: 2005

Patent us-7745120-b2

· 2010

Full title: us-7745120-b2

Year: 2010

Patent us-7470424-b2

· 2008

Full title: us-7470424-b2

Year: 2008

Patent us-7659441-b2

· 2010

Full title: us-7659441-b2

Year: 2010

Patent us-7691369-b2

· 2010

Full title: us-7691369-b2

Year: 2010

Patent us-7468264-b2

· 2008

Full title: us-7468264-b2

Year: 2008

Patent us-7604934-b2

· 2009

Full title: us-7604934-b2

Year: 2009

Patent us-7449306-b2

· 2008

Full title: us-7449306-b2

Year: 2008

Patent us-8241905-b2

· 2012

Full title: us-8241905-b2

Year: 2012

Patent us-7763456-b2

· 2010

Full title: us-7763456-b2

Year: 2010

Patent us-7682781-b2

· 2010

Full title: us-7682781-b2

Year: 2010

Patent us-8318479-b2

· 2012

Full title: us-8318479-b2

Year: 2012

Patent us-8012456-b2

· 2011

Full title: us-8012456-b2

Year: 2011

Patent us-8481303-b2

· 2013

Full title: us-8481303-b2

Year: 2013

Patent us-8747776-b2

· 2014

Full title: us-8747776-b2

Year: 2014

Patent us-8071381-b2

· 2011

Full title: us-8071381-b2

Year: 2011

Patent us-7393994-b2

· 2008

Full title: us-7393994-b2

Year: 2008

Patent us-9068281-b2

· 2015

Full title: us-9068281-b2

Year: 2015

Patent us-9090878-b2

· 2015

Full title: us-9090878-b2

Year: 2015

Patent us-9097702-b2

· 2015

Full title: us-9097702-b2

Year: 2015

Patent us-9029627-b2

· 2015

Full title: us-9029627-b2

Year: 2015

Patent us-9442105-b2

· 2016

Full title: us-9442105-b2

Year: 2016

Patent us-9267938-b2

· 2016

Full title: us-9267938-b2

Year: 2016

Patent us-9687348-b2

· 2017

Full title: us-9687348-b2

Year: 2017

Patent us-8771930-b2

· 2014

Full title: us-8771930-b2

Year: 2014

Patent us-9700024-b2

· 2017

Full title: us-9700024-b2

Year: 2017

Patent us-9610578-b2

· 2017

Full title: us-9610578-b2

Year: 2017

Patent us-8679843-b2

· 2014

Full title: us-8679843-b2

Year: 2014

Patent us-9506037-b2

· 2016

Full title: us-9506037-b2

Year: 2016

Patent us-9695399-b2

· 2017

Full title: us-9695399-b2

Year: 2017

Patent us-9810685-b2

· 2017

Full title: us-9810685-b2

Year: 2017

Patent us-9732316-b2

· 2017

Full title: us-9732316-b2

Year: 2017

Patent us-9506024-b2

· 2016

Full title: us-9506024-b2

Year: 2016

Patent us-9464271-b2

· 2016

Full title: us-9464271-b2

Year: 2016

Patent us-9217156-b2

· 2015

Full title: us-9217156-b2

Year: 2015

Patent us-9777258-b2

· 2017

Full title: us-9777258-b2

Year: 2017

Patent us-9743646-b2

· 2017

Full title: us-9743646-b2

Year: 2017

Patent us-9986724-b2

· 2018

Full title: us-9986724-b2

Year: 2018

Patent us-9901082-b2

· 2018

Full title: us-9901082-b2

Year: 2018

Patent us-9969979-b2

· 2018

Full title: us-9969979-b2

Year: 2018

Patent us-9752116-b2

· 2017

Full title: us-9752116-b2

Year: 2017

Patent us-2021395700-a1

· 2021

Full title: us-2021395700-a1

Year: 2021

Patent us-2022042975-a1

· 2022

Full title: us-2022042975-a1

Year: 2022

Patent us-2021371783-a1

· 2021

Full title: us-2021371783-a1

Year: 2021

Patent us-2021301238-a1

· 2021

Full title: us-2021301238-a1

Year: 2021

Patent us-2022081663-a1

· 2022

Full title: us-2022081663-a1

Year: 2022

Patent us-2021371792-a1

· 2021

Full title: us-2021371792-a1

Year: 2021

Patent us-2022081659-a1

· 2022

Full title: us-2022081659-a1

Year: 2022

Patent us-2022010282-a1

· 2022

Full title: us-2022010282-a1

Year: 2022

Patent us-2022072203-a1

· 2022

Full title: us-2022072203-a1

Year: 2022

Patent us-2022002655-a1

· 2022

Full title: us-2022002655-a1

Year: 2022

Patent us-2022056419-a1

· 2022

Full title: us-2022056419-a1

Year: 2022

Patent us-2022010252-a1

· 2022

Full title: us-2022010252-a1

Year: 2022

Patent us-2022016178-a1

· 2022

Full title: us-2022016178-a1

Year: 2022

Patent us-2022062791-a1

· 2022

Full title: us-2022062791-a1

Year: 2022

Patent us-2022042976-a1

· 2022

Full title: us-2022042976-a1

Year: 2022

Patent us-2021372995-a1

· 2021

Full title: us-2021372995-a1

Year: 2021

Patent us-2022074924-a1

· 2022

Full title: us-2022074924-a1

Year: 2022

Patent us-2022118446-a1

· 2022

Full title: us-2022118446-a1

Year: 2022

Patent us-2022010255-a1

· 2022

Full title: us-2022010255-a1

Year: 2022

Patent us-2022145259-a1

· 2022

Full title: us-2022145259-a1

Year: 2022

Patent us-2022177833-a1

· 2022

Full title: us-2022177833-a1

Year: 2022

Patent us-2022106547-a1

· 2022

Full title: us-2022106547-a1

Year: 2022

Patent us-2022130280-a1

· 2022

Full title: us-2022130280-a1

Year: 2022

Patent us-2022087233-a1

· 2022

Full title: us-2022087233-a1

Year: 2022

Patent us-2022229045-a1

· 2022

Full title: us-2022229045-a1

Year: 2022

Patent us-2022163511-a1

· 2022

Full title: us-2022163511-a1

Year: 2022

Patent us-2022238042-a1

· 2022

Full title: us-2022238042-a1

Year: 2022

Patent us-2022135941-a1

· 2022

Full title: us-2022135941-a1

Year: 2022

Patent us-2022145265-a1

· 2022

Full title: us-2022145265-a1

Year: 2022

Patent us-2022204903-a1

· 2022

Full title: us-2022204903-a1

Year: 2022

Patent us-2022192165-a1

· 2022

Full title: us-2022192165-a1

Year: 2022

Patent us-2022193676-a1

· 2022

Full title: us-2022193676-a1

Year: 2022

Patent us-2022205981-a1

· 2022

Full title: us-2022205981-a1

Year: 2022

Patent us-2022243160-a1

· 2022

Full title: us-2022243160-a1

Year: 2022

Patent us-2022266247-a1

· 2022

Full title: us-2022266247-a1

Year: 2022

Patent us-2022267720-a1

· 2022

Full title: us-2022267720-a1

Year: 2022

Patent us-2022220435-a1

· 2022

Full title: us-2022220435-a1

Year: 2022

Patent us-2022282221-a1

· 2022

Full title: us-2022282221-a1

Year: 2022

Patent us-2022259534-a1

· 2022

Full title: us-2022259534-a1

Year: 2022

Patent us-2022308045-a1

· 2022

Full title: us-2022308045-a1

Year: 2022

Patent us-2022291201-a1

· 2022

Full title: us-2022291201-a1

Year: 2022

Patent us-2022338465-a1

· 2022

Full title: us-2022338465-a1

Year: 2022

Patent us-2022330529-a1

· 2022

Full title: us-2022330529-a1

Year: 2022

Patent us-2022315899-a1

· 2022

Full title: us-2022315899-a1

Year: 2022

Patent us-2022297117-a1

· 2022

Full title: us-2022297117-a1

Year: 2022

Patent us-2022243171-a1

· 2022

Full title: us-2022243171-a1

Year: 2022

Patent us-2022340849-a1

· 2022

Full title: us-2022340849-a1

Year: 2022

Patent us-2022333064-a1

· 2022

Full title: us-2022333064-a1

Year: 2022

Patent us-2022403312-a9

· 2022

Full title: us-2022403312-a9

Year: 2022

Patent us-2022403339-a1

· 2022

Full title: us-2022403339-a1

Year: 2022

Patent us-2022396773-a1

· 2022

Full title: us-2022396773-a1

Year: 2022

Patent us-2022397564-a1

· 2022

Full title: us-2022397564-a1

Year: 2022

Patent us-2022331502-a1

· 2022

Full title: us-2022331502-a1

Year: 2022

Patent us-2022404339-a1

· 2022

Full title: us-2022404339-a1

Year: 2022

Patent us-2022411750-a1

· 2022

Full title: us-2022411750-a1

Year: 2022

Patent us-2023091038-a1

· 2023

Full title: us-2023091038-a1

Year: 2023

Patent us-2023026247-a1

· 2023

Full title: us-2023026247-a1

Year: 2023

Patent us-2023027317-a1

· 2023

Full title: us-2023027317-a1

Year: 2023

Patent us-2023015127-a1

· 2023

Full title: us-2023015127-a1

Year: 2023

Patent us-2023002727-a1

· 2023

Full title: us-2023002727-a1

Year: 2023

Patent us-2023138186-a1

· 2023

Full title: us-2023138186-a1

Year: 2023

Patent us-2023095466-a1

· 2023

Full title: us-2023095466-a1

Year: 2023

Patent us-2023093162-a1

· 2023

Full title: us-2023093162-a1

Year: 2023

Patent us-2023022203-a1

· 2023

Full title: us-2023022203-a1

Year: 2023

Patent us-2023088277-a1

· 2023

Full title: us-2023088277-a1

Year: 2023

Patent us-2023095498-a1

· 2023

Full title: us-2023095498-a1

Year: 2023

Patent us-2023138759-a1

· 2023

Full title: us-2023138759-a1

Year: 2023

Patent us-2023032623-a1

· 2023

Full title: us-2023032623-a1

Year: 2023

Patent us-2023172172-a1

· 2023

Full title: us-2023172172-a1

Year: 2023

Patent us-2023151333-a1

· 2023

Full title: us-2023151333-a1

Year: 2023

Patent us-2023193182-a1

· 2023

Full title: us-2023193182-a1

Year: 2023

Patent us-2023159899-a1

· 2023

Full title: us-2023159899-a1

Year: 2023

Patent us-2023159871-a1

· 2023

Full title: us-2023159871-a1

Year: 2023

Patent us-2023146860-a1

· 2023

Full title: us-2023146860-a1

Year: 2023

Patent us-2023159896-a1

· 2023

Full title: us-2023159896-a1

Year: 2023

Patent us-2023147702-a1

· 2023

Full title: us-2023147702-a1

Year: 2023

Patent us-2023235289-a1

· 2023

Full title: us-2023235289-a1

Year: 2023

Patent us-2023174909-a1

· 2023

Full title: us-2023174909-a1

Year: 2023

Patent us-2023250377-a1

· 2023

Full title: us-2023250377-a1

Year: 2023

Patent us-2023257716-a1

· 2023

Full title: us-2023257716-a1

Year: 2023

Patent us-2023357694-a1

· 2023

Full title: us-2023357694-a1

Year: 2023

Patent us-2023280261-a1

· 2023

Full title: us-2023280261-a1

Year: 2023

Patent us-2023255195-a1

· 2023

Full title: us-2023255195-a1

Year: 2023

Patent us-2023340419-a1

· 2023

Full title: us-2023340419-a1

Year: 2023

Patent us-2023220353-a1

· 2023

Full title: us-2023220353-a1

Year: 2023

Patent us-2023381773-a1

· 2023

Full title: us-2023381773-a1

Year: 2023

Patent us-2023287355-a1

· 2023

Full title: us-2023287355-a1

Year: 2023

Patent us-2023265393-a1

· 2023

Full title: us-2023265393-a1

Year: 2023

Patent us-11066633-b2

· 2021

Full title: us-11066633-b2

Year: 2021

Patent us-11116799-b2

· 2021

Full title: us-11116799-b2

Year: 2021

Patent us-11332717-b2

· 2022

Full title: us-11332717-b2

Year: 2022

Patent us-11365396-b2

· 2022

Full title: us-11365396-b2

Year: 2022

Patent us-11324779-b2

· 2022

Full title: us-11324779-b2

Year: 2022

Patent us-11272695-b2

· 2022

Full title: us-11272695-b2

Year: 2022

Patent us-10323229-b1

· 2019

Full title: us-10323229-b1

Year: 2019

Patent us-11268950-b2

· 2022

Full title: us-11268950-b2

Year: 2022

Patent us-11459542-b2

· 2022

Full title: us-11459542-b2

Year: 2022

Patent us-11401501-b2

· 2022

Full title: us-11401501-b2

Year: 2022

Patent us-11407979-b2

· 2022

Full title: us-11407979-b2

Year: 2022

Patent us-11479752-b2

· 2022

Full title: us-11479752-b2

Year: 2022

Patent us-11326149-b2

· 2022

Full title: us-11326149-b2

Year: 2022

Patent us-11384328-b2

· 2022

Full title: us-11384328-b2

Year: 2022

Patent us-11406975-b2

· 2022

Full title: us-11406975-b2

Year: 2022

Patent us-11542462-b2

· 2023

Full title: us-11542462-b2

Year: 2023

Patent us-11492595-b2

· 2022

Full title: us-11492595-b2

Year: 2022

Patent us-11464640-b2

· 2022

Full title: us-11464640-b2

Year: 2022

Patent us-11473061-b2

· 2022

Full title: us-11473061-b2

Year: 2022

Patent us-11499127-b2

· 2022

Full title: us-11499127-b2

Year: 2022

Patent us-11493428-b2

· 2022

Full title: us-11493428-b2

Year: 2022

Patent us-11566212-b2

· 2023

Full title: us-11566212-b2

Year: 2023

Patent us-11542476-b2

· 2023

Full title: us-11542476-b2

Year: 2023

Patent us-11622546-b2

· 2023

Full title: us-11622546-b2

Year: 2023

Patent us-11542475-b2

· 2023

Full title: us-11542475-b2

Year: 2023

Patent us-11589562-b2

· 2023

Full title: us-11589562-b2

Year: 2023

Patent us-11566231-b2

· 2023

Full title: us-11566231-b2

Year: 2023

Patent us-11547101-b2

· 2023

Full title: us-11547101-b2

Year: 2023

Patent us-11840683-b2

· 2023

Full title: us-11840683-b2

Year: 2023

Patent us-11628437-b2

· 2023

Full title: us-11628437-b2

Year: 2023

Patent us-11628382-b2

· 2023

Full title: us-11628382-b2

Year: 2023

Patent us-11782051-b2

· 2023

Full title: us-11782051-b2

Year: 2023

Patent us-11685900-b2

· 2023

Full title: us-11685900-b2

Year: 2023

Patent us-11629319-b2

· 2023

Full title: us-11629319-b2

Year: 2023

Patent us-11725190-b2

· 2023

Full title: us-11725190-b2

Year: 2023

Patent us-11833512-b2

· 2023

Full title: us-11833512-b2

Year: 2023

Patent us-11845920-b2

· 2023

Full title: us-11845920-b2

Year: 2023

Patent us-11781101-b2

· 2023

Full title: us-11781101-b2

Year: 2023

Patent us-11841361-b2

· 2023

Full title: us-11841361-b2

Year: 2023

Patent us-11820966-b2

· 2023

Full title: us-11820966-b2

Year: 2023

Patent us-11788063-b2

· 2023

Full title: us-11788063-b2

Year: 2023

Patent us-11865536-b2

· 2024

Full title: us-11865536-b2

Year: 2024

Patent us-11834641-b2

· 2023

Full title: us-11834641-b2

Year: 2023

Patent us-11920162-b2

· 2024

Full title: us-11920162-b2

Year: 2024

Patent us-11920114-b2

· 2024

Full title: us-11920114-b2

Year: 2024

Patent us-11913940-b2

· 2024

Full title: us-11913940-b2

Year: 2024

Patent us-11932839-b2

· 2024

Full title: us-11932839-b2

Year: 2024

Patent us-11987813-b2

· 2024

Full title: us-11987813-b2

Year: 2024

Patent us-11925726-b2

· 2024

Full title: us-11925726-b2

Year: 2024

Patent us-11993785-b2

· 2024

Full title: us-11993785-b2

Year: 2024

Patent us-12110507-b2

· 2024

Full title: us-12110507-b2

Year: 2024

Patent us-12054698-b2

· 2024

Full title: us-12054698-b2

Year: 2024

Patent us-11981926-b2

· 2024

Full title: us-11981926-b2

Year: 2024

Patent us-11982668-b2

· 2024

Full title: us-11982668-b2

Year: 2024

Patent us-11920116-b2

· 2024

Full title: us-11920116-b2

Year: 2024

Patent us-12128072-b2

· 2024

Full title: us-12128072-b2

Year: 2024

Patent us-12110479-b2

· 2024

Full title: us-12110479-b2

Year: 2024

Patent us-12180447-b2

· 2024

Full title: us-12180447-b2

Year: 2024

Patent us-12098352-b2

· 2024

Full title: us-12098352-b2

Year: 2024

Patent us-12158464-b2

· 2024

Full title: us-12158464-b2

Year: 2024

Patent us-12100143-b2

· 2024

Full title: us-12100143-b2

Year: 2024

Patent us-12134759-b2

· 2024

Full title: us-12134759-b2

Year: 2024

Patent us-12180446-b2

· 2024

Full title: us-12180446-b2

Year: 2024

Patent us-12377413-b2

· 2025

Full title: us-12377413-b2

Year: 2025

Patent us-12180507-b2

· 2024

Full title: us-12180507-b2

Year: 2024

Patent us-12247223-b2

· 2025

Full title: us-12247223-b2

Year: 2025

Patent us-12241049-b2

· 2025

Full title: us-12241049-b2

Year: 2025

Patent us-12252712-b2

· 2025

Full title: us-12252712-b2

Year: 2025

Patent us-12351820-b2

· 2025

Full title: us-12351820-b2

Year: 2025

Patent us-12303806-b2

· 2025

Full title: us-12303806-b2

Year: 2025

Patent us-12378528-b2

· 2025

Full title: us-12378528-b2

Year: 2025

Patent us-12275957-b2

· 2025

Full title: us-12275957-b2

Year: 2025

Patent us-12305153-b2

· 2025

Full title: us-12305153-b2

Year: 2025

Patent us-12384993-b2

· 2025

Full title: us-12384993-b2

Year: 2025

Patent us-12018284-b2

· 2024

Full title: us-12018284-b2

Year: 2024

Patent us-12270016-b1

· 2025

Full title: us-12270016-b1

Year: 2025

Patent us-2001055806-a1

· 2001

Full title: us-2001055806-a1

Year: 2001

Patent us-2003064358-a1

· 2003

Full title: us-2003064358-a1

Year: 2003

Patent us-2003017142-a1

· 2003

Full title: us-2003017142-a1

Year: 2003

Patent us-2003044883-a1

· 2003

Full title: us-2003044883-a1

Year: 2003

Patent us-12391926-b2

· 2025

Full title: us-12391926-b2

Year: 2025

Patent us-12448607-b2

· 2025

Full title: us-12448607-b2

Year: 2025

Patent us-2004006373-a1

· 2004

Full title: us-2004006373-a1

Year: 2004

Patent us-2004197907-a1

· 2004

Full title: us-2004197907-a1

Year: 2004

Patent us-2004219513-a1

· 2004

Full title: us-2004219513-a1

Year: 2004

Patent us-2004228795-a1

· 2004

Full title: us-2004228795-a1

Year: 2004

Patent us-2004214226-a1

· 2004

Full title: us-2004214226-a1

Year: 2004

Patent us-2006172416-a1

· 2006

Full title: us-2006172416-a1

Year: 2006

Patent us-2004152149-a1

· 2004

Full title: us-2004152149-a1

Year: 2004

Patent us-2005260745-a1

· 2005

Full title: us-2005260745-a1

Year: 2005

Patent us-2006026701-a1

· 2006

Full title: us-2006026701-a1

Year: 2006

Patent us-2006190043-a1

· 2006

Full title: us-2006190043-a1

Year: 2006

Patent us-2007037277-a1

· 2007

Full title: us-2007037277-a1

Year: 2007

Patent us-2007044162-a1

· 2007

Full title: us-2007044162-a1

Year: 2007

Patent us-2007224677-a1

· 2007

Full title: us-2007224677-a1

Year: 2007

Patent us-2007186289-a1

· 2007

Full title: us-2007186289-a1

Year: 2007

Patent us-2008293133-a1

· 2008

Full title: us-2008293133-a1

Year: 2008

Patent us-2008288399-a1

· 2008

Full title: us-2008288399-a1

Year: 2008

Patent us-2008070304-a1

· 2008

Full title: us-2008070304-a1

Year: 2008

Patent us-2007048727-a1

· 2007

Full title: us-2007048727-a1

Year: 2007

Patent us-2009011504-a1

· 2009

Full title: us-2009011504-a1

Year: 2009

Patent us-2008102478-a1

· 2008

Full title: us-2008102478-a1

Year: 2008

Patent us-2009191631-a1

· 2009

Full title: us-2009191631-a1

Year: 2009

Patent us-2009117584-a1

· 2009

Full title: us-2009117584-a1

Year: 2009

Patent us-2009068701-a1

· 2009

Full title: us-2009068701-a1

Year: 2009

Patent us-2009038020-a1

· 2009

Full title: us-2009038020-a1

Year: 2009

Patent us-2010275278-a1

· 2010

Full title: us-2010275278-a1

Year: 2010

Patent us-2011091930-a1

· 2011

Full title: us-2011091930-a1

Year: 2011

Patent us-2010122357-a1

· 2010

Full title: us-2010122357-a1

Year: 2010

Patent us-2010056390-a1

· 2010

Full title: us-2010056390-a1

Year: 2010

Patent us-2009104164-a1

· 2009

Full title: us-2009104164-a1

Year: 2009

Patent us-2010173333-a1

· 2010

Full title: us-2010173333-a1

Year: 2010

Patent us-2011086427-a1

· 2011

Full title: us-2011086427-a1

Year: 2011

Patent us-2011229970-a1

· 2011

Full title: us-2011229970-a1

Year: 2011

Patent us-2012083425-a1

· 2012

Full title: us-2012083425-a1

Year: 2012

Patent us-2013143230-a1

· 2013

Full title: us-2013143230-a1

Year: 2013

Patent us-2012156670-a1

· 2012

Full title: us-2012156670-a1

Year: 2012

Patent us-2012035742-a1

· 2012

Full title: us-2012035742-a1

Year: 2012

Patent us-2012009672-a1

· 2012

Full title: us-2012009672-a1

Year: 2012

Patent us-2013115606-a1

· 2013

Full title: us-2013115606-a1

Year: 2013

Patent us-2012231976-a1

· 2012

Full title: us-2012231976-a1

Year: 2012

Patent us-2013273589-a1

· 2013

Full title: us-2013273589-a1

Year: 2013

Patent us-2014273220-a1

· 2014

Full title: us-2014273220-a1

Year: 2014

Patent us-2013266939-a1

· 2013

Full title: us-2013266939-a1

Year: 2013

Patent us-2013198874-a1

· 2013

Full title: us-2013198874-a1

Year: 2013

Patent us-2013130301-a1

· 2013

Full title: us-2013130301-a1

Year: 2013

Patent us-2014011197-a1

· 2014

Full title: us-2014011197-a1

Year: 2014

Patent us-2015184124-a1

· 2015

Full title: us-2015184124-a1

Year: 2015

Patent us-2014221225-a1

· 2014

Full title: us-2014221225-a1

Year: 2014

Patent us-2014134662-a1

· 2014

Full title: us-2014134662-a1

Year: 2014

Patent us-2013295598-a1

· 2013

Full title: us-2013295598-a1

Year: 2013

Patent us-2014287960-a1

· 2014

Full title: us-2014287960-a1

Year: 2014

Patent us-2014274802-a1

· 2014

Full title: us-2014274802-a1

Year: 2014

Patent us-2014373186-a1

· 2014

Full title: us-2014373186-a1

Year: 2014

Patent us-2015074835-a1

· 2015

Full title: us-2015074835-a1

Year: 2015

Patent us-2014274953-a1

· 2014

Full title: us-2014274953-a1

Year: 2014

Patent us-2014363473-a1

· 2014

Full title: us-2014363473-a1

Year: 2014

Patent us-2015004273-a1

· 2015

Full title: us-2015004273-a1

Year: 2015

Patent us-2015253232-a1

· 2015

Full title: us-2015253232-a1

Year: 2015

Patent us-2015264901-a1

· 2015

Full title: us-2015264901-a1

Year: 2015

Patent us-2015252328-a1

· 2015

Full title: us-2015252328-a1

Year: 2015

Patent us-2015240194-a1

· 2015

Full title: us-2015240194-a1

Year: 2015

Patent us-2015240203-a1

· 2015

Full title: us-2015240203-a1

Year: 2015

Patent us-2015275176-a1

· 2015

Full title: us-2015275176-a1

Year: 2015

Patent us-2015282459-a1

· 2015

Full title: us-2015282459-a1

Year: 2015

Patent us-10119107-b2

· 2018

Full title: us-10119107-b2

Year: 2018

Patent us-10400219-b2

· 2019

Full title: us-10400219-b2

Year: 2019

Patent us-10517731-b2

· 2019

Full title: us-10517731-b2

Year: 2019

Patent us-10717966-b2

· 2020

Full title: us-10717966-b2

Year: 2020

Patent us-10688221-b2

· 2020

Full title: us-10688221-b2

Year: 2020

Patent us-10801015-b2

· 2020

Full title: us-10801015-b2

Year: 2020

Patent us-11001811-b2

· 2021

Full title: us-11001811-b2

Year: 2021

Patent us-11230688-b2

· 2022

Full title: us-11230688-b2

Year: 2022

Patent us-11778995-b2

· 2023

Full title: us-11778995-b2

Year: 2023

Patent us-11952592-b2

· 2024

Full title: us-11952592-b2

Year: 2024

Patent us-12241085-b2

· 2025

Full title: us-12241085-b2

Year: 2025

Patent us-2003033615-a1

· 2003

Full title: us-2003033615-a1

Year: 2003

Patent us-2006154235-a1

· 2006

Full title: us-2006154235-a1

Year: 2006

Patent us-2012208211-a1

· 2012

Full title: us-2012208211-a1

Year: 2012

Patent us-2016017283-a1

· 2016

Full title: us-2016017283-a1

Year: 2016

Patent us-2015079673-a1

· 2015

Full title: us-2015079673-a1

Year: 2015

Patent us-2016281064-a1

· 2016

Full title: us-2016281064-a1

Year: 2016

Patent us-2018057796-a1

· 2018

Full title: us-2018057796-a1

Year: 2018

Patent us-2018312810-a1

· 2018

Full title: us-2018312810-a1

Year: 2018

Patent us-2019040348-a1

· 2019

Full title: us-2019040348-a1

Year: 2019

Patent us-2019249137-a1

· 2019

Full title: us-2019249137-a1

Year: 2019

Patent us-2020087628-a1

· 2020

Full title: us-2020087628-a1

Year: 2020

Patent us-2020190479-a1

· 2020

Full title: us-2020190479-a1

Year: 2020

Patent us-2021054323-a1

· 2021

Full title: us-2021054323-a1

Year: 2021

Patent us-2021324311-a1

· 2021

Full title: us-2021324311-a1

Year: 2021

Patent us-2022095596-a1

· 2022

Full title: us-2022095596-a1

Year: 2022

Patent us-2022217970-a1

· 2022

Full title: us-2022217970-a1

Year: 2022

Patent us-2022250055-a1

· 2022

Full title: us-2022250055-a1

Year: 2022

Patent us-2023002714-a1

· 2023

Full title: us-2023002714-a1

Year: 2023

Patent us-2023357690-a1

· 2023

Full title: us-2023357690-a1

Year: 2023

Patent us-2024026263-a1

· 2024

Full title: us-2024026263-a1

Year: 2024

Patent us-2023383262-a1

· 2023

Full title: us-2023383262-a1

Year: 2023

Patent us-2024150692-a1

· 2024

Full title: us-2024150692-a1

Year: 2024

Patent us-2024279612-a1

· 2024

Full title: us-2024279612-a1

Year: 2024

Patent us-2024344004-a1

· 2024

Full title: us-2024344004-a1

Year: 2024

Patent us-2024228976-a1

· 2024

Full title: us-2024228976-a1

Year: 2024

Patent us-2025034530-a1

· 2025

Full title: us-2025034530-a1

Year: 2025

Patent us-2024376437-a1

· 2024

Full title: us-2024376437-a1

Year: 2024

Patent us-5624839-a

· 1997

Full title: us-5624839-a

Year: 1997

Patent us-5569812-a

· 1996

Full title: us-5569812-a

Year: 1996

Patent us-7022506-b2

· 2006

Full title: us-7022506-b2

Year: 2006

Metadata only

Paper Hepatitis C. Development of new drugs and clinical trials: Promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February 27-March 1, 2003

Pawlotsky, Jean–Michel; McHutchison, John G. · 2004 · Hepatology · DOI

Full title: Hepatitis C. Development of new drugs and clinical trials: Promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February 27-March 1, 2003

Authors: Pawlotsky, Jean–Michel; McHutchison, John G.

Year: 2004

Venue: Hepatology

DOI: https://doi.org/10.1002/hep.20065

Paper Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts

Napiwocki, Brett N.; Lang, Di; Stempien, Alana et al. · 2020 · Biotechnology and Bioengineering · DOI

Full title: Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts

Authors: Napiwocki, Brett N.; Lang, Di; Stempien, Alana; Zhang, J.; Vaidyanathan, Rajiv; Makielski, Jonathan C.; Eckhardt, Lee L.; Glukhov, Alexey V.; Kamp, Timothy J.; Crone, Wendy C.

Year: 2020

Venue: Biotechnology and Bioengineering

DOI: https://doi.org/10.1002/bit.27582

Paper The ongoing trends of patient‐derived xenograft models in oncology

Zhuo, Jianyong; Su, Renyi; Tan, Winyen et al. · 2020 · Cancer Communications · DOI

Full title: The ongoing trends of patient‐derived xenograft models in oncology

Authors: Zhuo, Jianyong; Su, Renyi; Tan, Winyen; Lian, Zhengxing; Lu, Di; Xu, Xiao

Year: 2020

Venue: Cancer Communications

DOI: https://doi.org/10.1002/cac2.12096

Paper Liver fibrosis: Which mechanisms matter?

Weiskirchen, Ralf; Tacke, Frank · 2016 · Clinical Liver Disease · DOI

Full title: Liver fibrosis: Which mechanisms matter?

Authors: Weiskirchen, Ralf; Tacke, Frank

Year: 2016

Venue: Clinical Liver Disease

DOI: https://doi.org/10.1002/cld.581

Paper Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research

Inui, Jumpei; Ueyama-Toba, Yukiko; Imamura, Chiharu et al. · 2025 · Biomaterials · DOI

Full title: Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research

Authors: Inui, Jumpei; Ueyama-Toba, Yukiko; Imamura, Chiharu; Nagai, Wakana; Asano, Rei; Mizuguchi, Hiroyuki

Year: 2025

Venue: Biomaterials

DOI: https://doi.org/10.1016/j.biomaterials.2025.123148

Paper Application of human induced pluripotent stem cells to model fibrodysplasia ossificans progressiva.

Barruet, Emilie; Hsiao, Edward C · 2018 · Bone · DOI

Full title: Application of human induced pluripotent stem cells to model fibrodysplasia ossificans progressiva.

Authors: Barruet, Emilie; Hsiao, Edward C

Year: 2018

Venue: Bone

DOI: https://doi.org/10.1016/j.bone.2017.07.003

Paper A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell–derived kidney model for drug discovery

Boreström, Cecilia; Jonebring, Anna; Guo, Jing et al. · 2018 · Kidney International · DOI

Full title: A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell–derived kidney model for drug discovery

Authors: Boreström, Cecilia; Jonebring, Anna; Guo, Jing; Palmgren, Henrik; Cederblad, Linda; Forslöw, Anna; Svensson, Anna; Söderberg, Magnus; Reznichenko, Anna; Nyström, Jenny; Patrakka, Jaakko; Hicks, Ryan; Maresca, Marcello; Valastro, Barbara; Collén, Anna

Year: 2018

Venue: Kidney International

DOI: https://doi.org/10.1016/j.kint.2018.05.003

Paper Endless healing: TGF‐β, SMADs, and fibrosis

Eickelberg, Oliver · 2001 · FEBS Letters · DOI

Full title: Endless healing: TGF‐β, SMADs, and fibrosis

Authors: Eickelberg, Oliver

Year: 2001

Venue: FEBS Letters

DOI: https://doi.org/10.1016/s0014-5793(01)02875-7

Paper Skin Penetration and Cellular Uptake of Amorphous Silica Nanoparticles with Variable Size, Surface Functionalization, and Colloidal Stability

Rancan, Fiorenza; Gao, Qi; Gräf, Christina et al. · 2012 · ACS Nano · DOI

Full title: Skin Penetration and Cellular Uptake of Amorphous Silica Nanoparticles with Variable Size, Surface Functionalization, and Colloidal Stability

Authors: Rancan, Fiorenza; Gao, Qi; Gräf, Christina; Troppens, Stefan; Hadam, Sabrina; Hackbarth, Steffen; Kembuan, Cynthia; Blume‐Peytavi, Ulrike; Rühl, E.; Lademann, Jürgen; Vogt, Annika

Year: 2012

Venue: ACS Nano

DOI: https://doi.org/10.1021/nn301622h

Paper Targeting breast cancer stem cells

Wicha, Max S. · 2009 · The Breast · DOI

Full title: Targeting breast cancer stem cells

Authors: Wicha, Max S.

Year: 2009

Venue: The Breast

DOI: https://doi.org/10.1016/s0960-9776(09)70274-7

Paper The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

Henn, Anja · 2009 · ALTEX · DOI

Full title: The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

Authors: Henn, Anja

Year: 2009

Venue: ALTEX

DOI: https://doi.org/10.14573/altex.2009.2.83

Paper The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons

Singer, Cherie A.; Figueroa, Xavier A.; Batchelor, Robert H. et al. · 1999 · Journal of Neuroscience · DOI

Full title: The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons

Authors: Singer, Cherie A.; Figueroa, Xavier A.; Batchelor, Robert H.; Dorsa, Daniel M.

Year: 1999

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.19-07-02455.1999

Paper Mechanism of Toxicity in Rotenone Models of Parkinson's Disease

Sherer, Todd; Betarbet, Ranjita; Testa, Claudia et al. · 2003 · Journal of Neuroscience · DOI

Full title: Mechanism of Toxicity in Rotenone Models of Parkinson's Disease

Authors: Sherer, Todd; Betarbet, Ranjita; Testa, Claudia; Seo, Byoung Boo; Richardson, Jason R.; Kim, Jin Ho; Miller, Gary W.; Yagi, Takao; Matsuno‐Yagi, Akemi; Greenamyre, J. Timothy

Year: 2003

Venue: Journal of Neuroscience

DOI: https://doi.org/10.1523/jneurosci.23-34-10756.2003

Paper Design and application of microfluidic systems for in vitro pharmacokinetic evaluation of drug candidates.

Maguire, T J; Novik, E; Chao, P et al. · 2009 · Current drug metabolism · DOI

Full title: Design and application of microfluidic systems for in vitro pharmacokinetic evaluation of drug candidates.

Authors: Maguire, T J; Novik, E; Chao, P; Barminko, J; Nahmias, Y; Yarmush, M L; Cheng, K-C

Year: 2009

Venue: Current drug metabolism

DOI: https://doi.org/10.2174/138920009790820093

Paper Delivery of therapeutics to posterior eye segment: cell-encapsulating systems

Lo, Acy; Wong, FranciscaS.Y.; Tsang, K · 2017 · Neural Regeneration Research · DOI

Full title: Delivery of therapeutics to posterior eye segment: cell-encapsulating systems

Authors: Lo, Acy; Wong, FranciscaS.Y.; Tsang, K

Year: 2017

Venue: Neural Regeneration Research

DOI: https://doi.org/10.4103/1673-5374.205093

Paper Translational research

Mahalmani, Vidya; Sinha, Shweta; Chakrabarti, Amitava et al. · 2022 · Indian Journal of Pharmacology · DOI

Full title: Translational research

Authors: Mahalmani, Vidya; Sinha, Shweta; Chakrabarti, Amitava; Medhi, Bikash

Year: 2022

Venue: Indian Journal of Pharmacology

DOI: https://doi.org/10.4103/ijp.ijp_860_22

Paper Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

Fits, Leslie van der; Mourits, Sabine; Voerman, Jane S.A. et al. · 2009 · The Journal of Immunology · DOI

Full title: Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

Authors: Fits, Leslie van der; Mourits, Sabine; Voerman, Jane S.A.; Kant, Marius; Boon, Louis; Laman, Jon D.; Cornelissen, Ferry; Mus, Anne‐Marie; Florencia, Edwin F.; Prens, Errol P.; Lubberts, Erik

Year: 2009

Venue: The Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.0802999

Paper Non-contact monitoring of extra-cellular field potentials with a multi-electrode array.

Sharf, Tal; Hansma, Paul K; Hari, Mukund A et al. · 2019 · Lab on a chip · DOI

Full title: Non-contact monitoring of extra-cellular field potentials with a multi-electrode array.

Authors: Sharf, Tal; Hansma, Paul K; Hari, Mukund A; Kosik, Kenneth S

Year: 2019

Venue: Lab on a chip

DOI: https://doi.org/10.1039/c8lc00984h

Paper Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Dovey, Harry F.; John, Varghese; Anderson, J. P. et al. · 2001 · Journal of Neurochemistry · DOI

Full title: Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Authors: Dovey, Harry F.; John, Varghese; Anderson, J. P.; Chen, L. Z.; Andrieu, P. D. S. int; Fang, Lanlan; Freedman, Stephen B.; Folmer, B.; Goldbach, Erich; Holsztynska, Elzbieta J.; Hu, Kang; Johnson‐Wood, Kelly; Kennedy, S. L.; Kholodenko, Dora; Knops, Jeroen; Latimer, Lee H.; Lee, M.; Liao, Zhengchang; Lieberburg, Ivan; Motter, Ruth; Mutter, Linda; Nietz, J.; Quinn, Kevin P.; Sacchi, K. L.; Seubert, Peter; Shopp, George M.; Thorsett, Eugene D.; Tung, Jay S.; Wu, Jing; Yang, Shao-Hua; Yin, Chen; Schenk, Dale B.; May, Patrick C.; Altstiel, L.; Bender, Mark H.; Boggs, Leonard N.; Britton, T. C.; Clemens, James C.; Czilli, Dan L.; Dieckman-McGinty, Donna K.; Droste, J. J.; Fuson, Kimberly S.; Gitter, Bruce D.; Hyslop, Paul A.; Johnstone, Edward M.; Li, W‐Y.; Little, Sharon; Mabry, Thomas E.; Miller, F. DeWolfe; Ni, B.; Nissen, Jeffrey S.; Porter, Warren J.; Potts, B D; Reel, Jon K.; Stephenson, Diane; Su, Yuan; Shipley, Lisa A.; Whitesitt, Celia A.; Yin, Tao; Audia, James E.

Year: 2001

Venue: Journal of Neurochemistry

DOI: https://doi.org/10.1046/j.1471-4159.2001.00012.x

Paper Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential—towards a consensus

Tucker, Geoffrey T.; Houston, J. Brian; Huang, Shiew‐Mei · 2001 · British Journal of Clinical Pharmacology · DOI

Full title: Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential—towards a consensus

Authors: Tucker, Geoffrey T.; Houston, J. Brian; Huang, Shiew‐Mei

Year: 2001

Venue: British Journal of Clinical Pharmacology

DOI: https://doi.org/10.1046/j.0306-5251.2001.temp.1441.x

Paper Development of a Scalable Coculture System for Gut Anaerobes and Human Colon Epithelium

Sasaki, Nobuo; Miyamoto, Kentaro; Maslowski, Kendle M. et al. · 2020 · Gastroenterology · DOI

Full title: Development of a Scalable Coculture System for Gut Anaerobes and Human Colon Epithelium

Authors: Sasaki, Nobuo; Miyamoto, Kentaro; Maslowski, Kendle M.; Ohno, Hiroshi; Kanai∥, Takanori; Sato, Toshiro

Year: 2020

Venue: Gastroenterology

DOI: https://doi.org/10.1053/j.gastro.2020.03.021

Paper Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Zhang, Yu Shrike; Aleman, Julio; Shin, Su Ryon et al. · 2017 · Proceedings of the National Academy of Sciences · DOI

Full title: Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Authors: Zhang, Yu Shrike; Aleman, Julio; Shin, Su Ryon; Kiliç, Tuğba; Kim, Duck Jin; Shaegh, Seyed Ali Mousavi; Massa, Solange; Riahi, Reza; Chae, Sukyoung; Hu, Ning; Avcı, Hüseyin; Zhang, Weijia; Silvestri, Antonia; Sanati‐Nezhad, Amir; Manbohi, Ahmad; Ferrari, Fabio De; Polini, Alessandro; Calzone, Giovanni; Shaikh, Noor; Alerasool, Parissa; Budina, Erica; Kang, Jian; Bhise, Nupura; Ribas, João; Pourmand, Adel; Skardal, Aleksander; Shupe, Thomas; Bishop, Colin E.; Dokmeci, Mehmet R.; Atala, Anthony; Khademhosseini, Ali

Year: 2017

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1612906114

Paper Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

Ma, Xuanyi; Qu, Xin; Zhu, Wei et al. · 2016 · Proceedings of the National Academy of Sciences · DOI

Full title: Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

Authors: Ma, Xuanyi; Qu, Xin; Zhu, Wei; Li, Yi‐Shuan; Yuan, Suli; Zhang, Hong; Liu, Justin; Wang, Pengrui; Lai, Cheuk Sun Edwin; Zanella, Fabian; Feng, Gen‐Sheng; Sheikh, Farah; Chien, Shu; Chen, Shaochen

Year: 2016

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1524510113

Paper Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions

Pan, Cuiping; Kumar, Chanchal; Böhl, Sebastian et al. · 2008 · Molecular & Cellular Proteomics · DOI

Full title: Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions

Authors: Pan, Cuiping; Kumar, Chanchal; Böhl, Sebastian; Klingmueller, Ursula; Mann, Matthias

Year: 2008

Venue: Molecular & Cellular Proteomics

DOI: https://doi.org/10.1074/mcp.m800258-mcp200

Paper Orphan Nuclear Receptors: The Exotics of Xenobiotics

Xie, Wen; Evans, Ronald M. · 2001 · Journal of Biological Chemistry · DOI

Full title: Orphan Nuclear Receptors: The Exotics of Xenobiotics

Authors: Xie, Wen; Evans, Ronald M.

Year: 2001

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.r100033200

Paper A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3

Sabroe, Ian; Peck, Michael J.; KEULEN, B. J. VAN et al. · 2000 · Journal of Biological Chemistry · DOI

Full title: A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3

Authors: Sabroe, Ian; Peck, Michael J.; KEULEN, B. J. VAN; Jorritsma, Annelies; Simmons, Graham; Clapham, Paul R.; Williams, Timothy J.; Pease, James E.

Year: 2000

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.m908864199

Paper Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor

Kast-Woelbern, Heidi R.; Goodwin, Bryan; Tarr, Paul T. et al. · 2002 · Journal of Biological Chemistry · DOI

Full title: Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor

Authors: Kast-Woelbern, Heidi R.; Goodwin, Bryan; Tarr, Paul T.; Jones, Stacey A.; Anisfeld, Andrew M.; Stoltz, Catherine M.; Tontonoz, Peter; Kliewer, S. A.; Willson, Timothy M.; Edwards, Peter A.

Year: 2002

Venue: Journal of Biological Chemistry

DOI: https://doi.org/10.1074/jbc.m109326200

Paper Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling

Whiteaker, Jeffrey R.; Zhao, Lei; Yan, Ping et al. · 2015 · Molecular & Cellular Proteomics · DOI

Full title: Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling

Authors: Whiteaker, Jeffrey R.; Zhao, Lei; Yan, Ping; Ivey, Richard G.; Voytovich, Uliana J.; Moore, Heather D.; Lin, Chenwei; Paulovich, Amanda G.

Year: 2015

Venue: Molecular & Cellular Proteomics

DOI: https://doi.org/10.1074/mcp.o115.050351

Paper Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach

Summeren, Anke Van; Renes, Johan; Lizárraga, Daneida et al. · 2013 · OMICS A Journal of Integrative Biology · DOI

Full title: Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach

Authors: Summeren, Anke Van; Renes, Johan; Lizárraga, Daneida; Bouwman, Freek G.; Noben, Jean‐Paul; Delft, Joost H.M. van; Kleinjans, Jos; Mariman, Edwin C.M.

Year: 2013

Venue: OMICS A Journal of Integrative Biology

DOI: https://doi.org/10.1089/omi.2012.0079

Paper Three-Dimensional Cell Culture Matrices: State of the Art

Lee, Jungwoo; Cuddihy, Meghan; Kotov, Nicholas A. · 2008 · Tissue Engineering Part B Reviews · DOI

Full title: Three-Dimensional Cell Culture Matrices: State of the Art

Authors: Lee, Jungwoo; Cuddihy, Meghan; Kotov, Nicholas A.

Year: 2008

Venue: Tissue Engineering Part B Reviews

DOI: https://doi.org/10.1089/teb.2007.0150

Paper Extracellular cAMP activates molecular signalling pathways associated with sperm capacitation in bovines.

Alonso, Carlos Agustín I; Osycka-Salut, Claudia E; Castellano, Luciana et al. · 2017 · Molecular human reproduction · DOI

Full title: Extracellular cAMP activates molecular signalling pathways associated with sperm capacitation in bovines.

Authors: Alonso, Carlos Agustín I; Osycka-Salut, Claudia E; Castellano, Luciana; Cesari, Andreína; Di Siervi, Nicolás; Mutto, Adrián; Johannisson, Anders; Morrell, Jane M; Davio, Carlos; Perez-Martinez, Silvina

Year: 2017

Venue: Molecular human reproduction

DOI: https://doi.org/10.1093/molehr/gax030

Paper A liver-on-a-chip platform with bioprinted hepatic spheroids

Bhise, Nupura S.; Manoharan, Vijayan; Massa, Solange et al. · 2016 · Biofabrication · DOI

Full title: A liver-on-a-chip platform with bioprinted hepatic spheroids

Authors: Bhise, Nupura S.; Manoharan, Vijayan; Massa, Solange; Tamayol, Ali; Ghaderi, Masoumeh; Miscuglio, Mario; Lang, Qi; Zhang, Yu Shrike; Shin, Su Ryon; Calzone, Giovanni; Annabi, Nasim; Shupe, Thomas; Bishop, Colin E.; Atala, Anthony; Dokmeci, Mehmet R.; Khademhosseini, Ali

Year: 2016

Venue: Biofabrication

DOI: https://doi.org/10.1088/1758-5090/8/1/014101

Paper HIV infection and the gastrointestinal tract

Kotler, Donald P. · 2005 · AIDS · DOI

Full title: HIV infection and the gastrointestinal tract

Authors: Kotler, Donald P.

Year: 2005

Venue: AIDS

DOI: https://doi.org/10.1097/00002030-200501280-00002

Paper Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

Leung, Maxwell C. K.; Williams, Phillip L.; Benedetto, Alexandre et al. · 2008 · Toxicological Sciences · DOI

Full title: Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

Authors: Leung, Maxwell C. K.; Williams, Phillip L.; Benedetto, Alexandre; Au, Catherine; Helmcke, Kirsten J.; Aschner, Michael; Meyer, Joel N.

Year: 2008

Venue: Toxicological Sciences

DOI: https://doi.org/10.1093/toxsci/kfn121

Paper Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Xu, Jinghai J.; Henstock, Peter; Dunn, Margaret C. et al. · 2008 · Toxicological Sciences · DOI

Full title: Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Authors: Xu, Jinghai J.; Henstock, Peter; Dunn, Margaret C.; Smith, Arthur R.; Chabot, J; Graaf, David de

Year: 2008

Venue: Toxicological Sciences

DOI: https://doi.org/10.1093/toxsci/kfn109

Paper A novel EST‐derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2‐adrenergic receptor internalization and down‐regulation

Jiang, Xiaofeng; Pan, Hui; Nabhan, Joseph F. et al. · 2012 · The FASEB Journal · DOI

Full title: A novel EST‐derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2‐adrenergic receptor internalization and down‐regulation

Authors: Jiang, Xiaofeng; Pan, Hui; Nabhan, Joseph F.; Krishnan, Ramaswamy; Koziol‐White, Cynthia; Panettieri, Reynold A.; Lu, Quan

Year: 2012

Venue: The FASEB Journal

DOI: https://doi.org/10.1096/fj.11-193870

Paper Microphysiological Systems (“Organs‐on‐Chips”) for Drug Efficacy and Toxicity Testing

Low, Lucie A.; Tagle, DA · 2017 · Clinical and Translational Science · DOI

Full title: Microphysiological Systems (“Organs‐on‐Chips”) for Drug Efficacy and Toxicity Testing

Authors: Low, Lucie A.; Tagle, DA

Year: 2017

Venue: Clinical and Translational Science

DOI: https://doi.org/10.1111/cts.12444

Paper Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes

Cummings, Jeffrey L. · 2017 · Clinical and Translational Science · DOI

Full title: Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes

Authors: Cummings, Jeffrey L.

Year: 2017

Venue: Clinical and Translational Science

DOI: https://doi.org/10.1111/cts.12491

Paper Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

Constantinescu, Cris S.; Farooqi, Nasr; O’Brien, Kate et al. · 2011 · British Journal of Pharmacology · DOI

Full title: Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

Authors: Constantinescu, Cris S.; Farooqi, Nasr; O’Brien, Kate; Gran, Bruno

Year: 2011

Venue: British Journal of Pharmacology

DOI: https://doi.org/10.1111/j.1476-5381.2011.01302.x

Paper A cell‐based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair

Gordon, Gabriel M.; LaGier, Adriana J.; Ponchel, C. et al. · 2015 · Wound Repair and Regeneration · DOI

Full title: A cell‐based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair

Authors: Gordon, Gabriel M.; LaGier, Adriana J.; Ponchel, C.; Bauskar, Aditi; Itakura, Tatsuo; Jeong, Shinwu; Patel, Nitin; Fini, M. Elizabeth

Year: 2015

Venue: Wound Repair and Regeneration

DOI: https://doi.org/10.1111/wrr.12390

Paper Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6

Moritz, Molly S.; Tepp, William H.; Bradshaw, Marite et al. · 2018 · mSphere · DOI

Full title: Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6

Authors: Moritz, Molly S.; Tepp, William H.; Bradshaw, Marite; Johnson, Eric A.; Pellett, Sabine

Year: 2018

Venue: mSphere

DOI: https://doi.org/10.1128/msphere.00466-18

Paper Polymeric Scaffolds in Tissue Engineering Application: A Review

Dhandayuthapani, Brahatheeswaran; Yoshida, Yasuhiko; Maekawa, Toru et al. · 2011 · International Journal of Polymer Science · DOI

Full title: Polymeric Scaffolds in Tissue Engineering Application: A Review

Authors: Dhandayuthapani, Brahatheeswaran; Yoshida, Yasuhiko; Maekawa, Toru; Kumar, D. Sakthi

Year: 2011

Venue: International Journal of Polymer Science

DOI: https://doi.org/10.1155/2011/290602

Paper Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications

Szekalska, Marta; Puciłowska, Agata; Szymańska, Emilia et al. · 2016 · International Journal of Polymer Science · DOI

Full title: Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications

Authors: Szekalska, Marta; Puciłowska, Agata; Szymańska, Emilia; Ciosek, Patrycja; Winnicka, Katarzyna

Year: 2016

Venue: International Journal of Polymer Science

DOI: https://doi.org/10.1155/2016/7697031

Paper Efficiency of Human Epiphyseal Chondrocytes with Differential Replication Numbers for Cellular Therapy Products

Nasu, Michiyo; Takayama, Shinichiro; Umezawa, Akihiro · 2016 · BioMed Research International · DOI

Full title: Efficiency of Human Epiphyseal Chondrocytes with Differential Replication Numbers for Cellular Therapy Products

Authors: Nasu, Michiyo; Takayama, Shinichiro; Umezawa, Akihiro

Year: 2016

Venue: BioMed Research International

DOI: https://doi.org/10.1155/2016/6437658

Paper The in vitro Inhibitory Effect of Tannin Derivatives on 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase on Vero Cells

Chang, Jun‐Jen; Chen, Tso-Hsiao; Chan, Paul et al. · 2001 · Pharmacology · DOI

Full title: The in vitro Inhibitory Effect of Tannin Derivatives on 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase on Vero Cells

Authors: Chang, Jun‐Jen; Chen, Tso-Hsiao; Chan, Paul; Chen, Yi‐Jen; Hsu, Feng-Lin; Lo, Ming-Yu; Lin, Jung‐Yaw

Year: 2001

Venue: Pharmacology

DOI: https://doi.org/10.1159/000056099

Paper CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers

Cheng, Mangeng; Quail, Matthew R.; Gingrich, Diane E. et al. · 2011 · Molecular Cancer Therapeutics · DOI

Full title: CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers

Authors: Cheng, Mangeng; Quail, Matthew R.; Gingrich, Diane E.; Ott, Gregory R.; Lü, Lihui; Wan, Weihua; Albom, Mark S.; Angeles, Thelma S.; Aimone, Lisa D.; Cristofani, Flavio; Machiorlatti, Rodolfo; Abele, Cristina; Ator, Mark A.; Dorsey, Bruce D.; Inghirami, Giorgio; Ruggeri, Bruce

Year: 2011

Venue: Molecular Cancer Therapeutics

DOI: https://doi.org/10.1158/1535-7163.mct-11-0776

Paper Brown Fat Develops a <i>Brite</i> Future

Klingenspor, Martin; Herzig, Stephan; Pfeifer, Alexander · 2012 · Obesity Facts · DOI

Full title: Brown Fat Develops a <i>Brite</i> Future

Authors: Klingenspor, Martin; Herzig, Stephan; Pfeifer, Alexander

Year: 2012

Venue: Obesity Facts

DOI: https://doi.org/10.1159/000346337

Paper CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

Lannutti, Brian J.; Meadows, Sarah; Herman, Sarah E.M. et al. · 2010 · Blood · DOI

Full title: CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

Authors: Lannutti, Brian J.; Meadows, Sarah; Herman, Sarah E.M.; Kashishian, Adam; Steiner, Bart; Johnson, Amy J.; Byrd, John C.; Tyner, Jeffrey; Loriaux, Marc; Deininger, Mike; Druker, Brian; Puri, Kamal D.; Ulrich, Roger G.; Giese, Neill A.

Year: 2010

Venue: Blood

DOI: https://doi.org/10.1182/blood-2010-03-275305

Paper The relevance and potential roles of microphysiological systems in biology and medicine

Wikswo, John P. · 2014 · Experimental Biology and Medicine · DOI

Full title: The relevance and potential roles of microphysiological systems in biology and medicine

Authors: Wikswo, John P.

Year: 2014

Venue: Experimental Biology and Medicine

DOI: https://doi.org/10.1177/1535370214542068

Paper Gene Therapy for Lad-I Immunodeficiency: Preclinical Evaluation of HSC Transduction Under Optimized GMP-Conditions

Almarza, Elena; Mesa-Núñez, Cristina; Damián, Carlos et al. · 2019 · Blood · DOI

Full title: Gene Therapy for Lad-I Immunodeficiency: Preclinical Evaluation of HSC Transduction Under Optimized GMP-Conditions

Authors: Almarza, Elena; Mesa-Núñez, Cristina; Damián, Carlos; Fernández-García, María; Díez, Begoña; Lozano, M. Luz; Rı́o, Paula; Yáñez, Rosa María Pérez; Law, Ken; Beard, Brian C.; Schwartz, Jonathan D.; Bueren, Juan A.

Year: 2019

Venue: Blood

DOI: https://doi.org/10.1182/blood-2019-122878

Paper Inhibition of HIF1A Signaling by a Novel Class of Sulfonanilides for Targeted Treatment of Multiple Myeloma.

Hose, Dirk; Seckinger, Anja; Goldschmidt, Hartmut et al. · 2009 · Blood · DOI

Full title: Inhibition of HIF1A Signaling by a Novel Class of Sulfonanilides for Targeted Treatment of Multiple Myeloma.

Authors: Hose, Dirk; Seckinger, Anja; Goldschmidt, Hartmut; Meiβner, Tobias; Rebacz, Blanka; Moreaux, Jérôme; Beneš, Vladimı́r; Neben, Kai; Hillengaß, Jens; Bertsch, Uta; Jauch, Anna; Rossi, Jean François; Möhler, Thomas; Zimmermann, Jürgen; Kalle, Christof von; Lewis, Joe; Klein, Bernard; Schultes, Christoph

Year: 2009

Venue: Blood

DOI: https://doi.org/10.1182/blood.v114.22.2856.2856

Paper Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Aluri, Srinivas; Bachiashvili, Kimo; Budhathoki, Anjali et al. · 2019 · Blood · DOI

Full title: Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Authors: Aluri, Srinivas; Bachiashvili, Kimo; Budhathoki, Anjali; Bhagat, Tushar D.; Choudhary, Gaurav S.; Gordon, Shanisha; Ramachandra, Nandini; Pradhan, Kith; Maqbool, Shahina B.; Shastri, Aditi; Huh, Jung Im; Hwang, Sun-Jin; Seong-Jin, Kim; Zhang, Hui; Will, Britta; Wickrema, Amittha; Steidl, Ulrich; Verma, Amit

Year: 2019

Venue: Blood

DOI: https://doi.org/10.1182/blood-2019-127561

Paper Chromatin Accessibility Mapping of Primary Erythroid Cell Populations Leads to Identification and Validation of Nuclear Factor I X (NFIX) As a Novel Fetal Hemoglobin (HbF) Repressor

Chaand, Mudit; Fiore, Chris; Johnston, Brian et al. · 2019 · Blood · DOI

Full title: Chromatin Accessibility Mapping of Primary Erythroid Cell Populations Leads to Identification and Validation of Nuclear Factor I X (NFIX) As a Novel Fetal Hemoglobin (HbF) Repressor

Authors: Chaand, Mudit; Fiore, Chris; Johnston, Brian; Moon, Diane H.; Carulli, John P.; Shearstone, Jeffrey R.

Year: 2019

Venue: Blood

DOI: https://doi.org/10.1182/blood-2019-124337

Paper Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Yano, Hisashi; Shinohara, Tokuyuki; Koga, Keiko et al. · 2019 · Blood · DOI

Full title: Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Authors: Yano, Hisashi; Shinohara, Tokuyuki; Koga, Keiko; Iriguchi, Shoichi; Miyake, Y.; Song, Xuewei; Tada, Megumi; Kassai, Yoshiaki; Kiyoi, Hitoshi; Kaneko, Shin

Year: 2019

Venue: Blood

DOI: https://doi.org/10.1182/blood-2019-122193

Paper A Phase 1b/2 Study of TAK-981, a First-in-Class Sumoylation Inhibitor, in Combination with Rituximab in Patients with Relapsed/Refractory (r/r) CD20-Positive Non-Hodgkin Lymphoma (NHL)

Assouline, Sarit; Mehta, Amitkumar; Caimi, Paolo F. et al. · 2019 · Blood · DOI

Full title: A Phase 1b/2 Study of TAK-981, a First-in-Class Sumoylation Inhibitor, in Combination with Rituximab in Patients with Relapsed/Refractory (r/r) CD20-Positive Non-Hodgkin Lymphoma (NHL)

Authors: Assouline, Sarit; Mehta, Amitkumar; Caimi, Paolo F.; Wang, Bingxia; Patel, Chirag; Kim, Misook; Huszar, Dennis; Berger, Allison; Friedlander, Sharon; Gómez-Pinillos, Alejandro; Proscurshim, Igor

Year: 2019

Venue: Blood

DOI: https://doi.org/10.1182/blood-2019-128773

Paper CAL-101, An Oral p110δ Selective Phosphatidylinositol-3-Kinase (PI3K) Inhibitor for the Treatment of B Cell Malignancies Inhibits PI3K Signaling, Cellular Viability and Protective Signals of the Microenvironment.

Lannutti, Brian J.; Meadows, Sarah; Kashishian, Adam et al. · 2009 · Blood · DOI

Full title: CAL-101, An Oral p110δ Selective Phosphatidylinositol-3-Kinase (PI3K) Inhibitor for the Treatment of B Cell Malignancies Inhibits PI3K Signaling, Cellular Viability and Protective Signals of the Microenvironment.

Authors: Lannutti, Brian J.; Meadows, Sarah; Kashishian, Adam; Steiner, Bart; Pogosov, Galina; Sala‐Torra, Olga; Johnson, Amy J.; Byrd, John C.; Radich, Jerald P.; Giese, Neill A.

Year: 2009

Venue: Blood

DOI: https://doi.org/10.1182/blood.v114.22.286.286

Paper Dual PI3Kδ/γ Inhibition By RP6530 Induces Apoptosis and Cytotoxicity In B-Lymphoma Cells

Vakkalanka, Swaroop; Viswanadha, Srikant; Gaudio, Eugenio et al. · 2013 · Blood · DOI

Full title: Dual PI3Kδ/γ Inhibition By RP6530 Induces Apoptosis and Cytotoxicity In B-Lymphoma Cells

Authors: Vakkalanka, Swaroop; Viswanadha, Srikant; Gaudio, Eugenio; Zucca, Emanuele; Bertoni, Francesco; Bernasconi, Elena; Rossi, Davide; Stathis, Anastasios

Year: 2013

Venue: Blood

DOI: https://doi.org/10.1182/blood.v122.21.4411.4411

Paper TAK-169, a Novel Recombinant Immunotoxin Specific for CD38, Induces Powerful Preclinical Activity Against Patient-Derived Multiple Myeloma Cells

Bruins, Wassilis S.C.; Zheng, Wenrou; Higgins, Jack P. et al. · 2020 · Blood · DOI

Full title: TAK-169, a Novel Recombinant Immunotoxin Specific for CD38, Induces Powerful Preclinical Activity Against Patient-Derived Multiple Myeloma Cells

Authors: Bruins, Wassilis S.C.; Zheng, Wenrou; Higgins, Jack P.; Willert, Erin K.; Newcomb, John; Dash, Ajeeta B.; Donk, Niels W.C.J. van de; Zweegman, Sonja; Mutis, Tuna

Year: 2020

Venue: Blood

DOI: https://doi.org/10.1182/blood-2020-136928

Paper Evidence That Activated Hedgehog Signaling Predicts for Poor Clinical Outcome in Acute Myeloid Leukemia

Campbell, Veronica T.; Tholouli, Eleni; Quigley, Mikayla et al. · 2012 · Blood · DOI

Full title: Evidence That Activated Hedgehog Signaling Predicts for Poor Clinical Outcome in Acute Myeloid Leukemia

Authors: Campbell, Veronica T.; Tholouli, Eleni; Quigley, Mikayla; Keilty, John; Kelly, Patrick; McGovern, Karen; Read, Margaret; Kutok, Jeffery L.; Byers, Richard

Year: 2012

Venue: Blood

DOI: https://doi.org/10.1182/blood.v120.21.1441.1441

Paper Patient-Derived Xenografts (PDX) of B Cell Lymphoma in NSG Mice: A Mouse Avatar for Developing Personalized Medicine

Gerstein, Rachel M.; Zhou, Zheng; Zhang, Hong et al. · 2015 · Blood · DOI

Full title: Patient-Derived Xenografts (PDX) of B Cell Lymphoma in NSG Mice: A Mouse Avatar for Developing Personalized Medicine

Authors: Gerstein, Rachel M.; Zhou, Zheng; Zhang, Hong; Evens, Andrew M.; Walsh, Nicole C.; Shultz, Leonard D.; Bortell, Rita; Brehm, Michael A.; Černý, Jan; Whalen, Giles F.; Leonard, Jack L.; Woda, Bruce A.; Greiner, Dale L.; Rosmarin, Alan G.

Year: 2015

Venue: Blood

DOI: https://doi.org/10.1182/blood.v126.23.5408.5408

Paper Antileukemic Effects of the Novel Agent Elesclomol.

Chow, Sue; Nagai, Masazumi; He, Suqin et al. · 2009 · Blood · DOI

Full title: Antileukemic Effects of the Novel Agent Elesclomol.

Authors: Chow, Sue; Nagai, Masazumi; He, Suqin; Blackman, Ronald K.; Barsoum, James; Vukovic, Vojislav; Hedley, David W.

Year: 2009

Venue: Blood

DOI: https://doi.org/10.1182/blood.v114.22.2736.2736

Paper Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism

Aoki, Tomohiro; Shimada, Kazuyuki; Sakamoto, Akihiko et al. · 2016 · Blood · DOI

Full title: Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism

Authors: Aoki, Tomohiro; Shimada, Kazuyuki; Sakamoto, Akihiko; Sugimoto, Keiki; Morishita, Takanobu; Kojima, Yuki; Shimada, Satoko; Kato, Seiichi; Iriyama, Chisako; Kuno, S.; Harada, Yasuhiko; Nakamura, Shigeo; Tomita, Akihiro; Hayakawa, Fumihiko; Kiyoi, Hitoshi

Year: 2016

Venue: Blood

DOI: https://doi.org/10.1182/blood.v128.22.3019.3019

Paper B-Cell Maturation Antigen (BCMA)-Specific, CentyrinTM-Based, PiggyBacTM-Transposed CAR-T Memory Stem Cells Are Effective Against p53-/- and Patient-Derived Multiple Myeloma Tumors

Mathur, Rohit; Barnett, Burton E.; Hermanson, David et al. · 2017 · Blood · DOI

Full title: B-Cell Maturation Antigen (BCMA)-Specific, CentyrinTM-Based, PiggyBacTM-Transposed CAR-T Memory Stem Cells Are Effective Against p53-/- and Patient-Derived Multiple Myeloma Tumors

Authors: Mathur, Rohit; Barnett, Burton E.; Hermanson, David; He, Jin; Zhang, Zheng; Rengarajan, Srinivas; Codde, Rebecca; Wang, Xinxin; Tan, Yening; Martin, Christopher E.; Smith, Jenessa B.; Lee, Hans C.; Manasanch, Elisabet E.; Thomas, Sheeba K.; Patel, Krina K.; Weber, Donna M.; Davis, R. Eric; Orlowski, Robert Z.; Ostertag, Eric; Shedlock, Devon J.; Yang, Jing; Neelapu, Sattva S.

Year: 2017

Venue: Blood

DOI: https://doi.org/10.1182/blood.v130.suppl_1.3068.3068

Paper Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells

Feng, Sisi; Wu, Jiaying; Qiu, Wei‐Lin et al. · 2020 · Cell Reports · DOI

Full title: Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells

Authors: Feng, Sisi; Wu, Jiaying; Qiu, Wei‐Lin; Li, Yang; Deng, Xiaogang; Zhou, Ying; Chen, Yabin; Xiao, Li; Yu, Lei; Li, Hongsheng; Xu, Ziran; Xiao, Yini; Ren, Xiongzhao; Zhang, Ludi; Wang, Chenhua; Sun, Zhen; Wang, Jinglin; Ding, Xiaoyan; Chen, Yue‐Lei; Gadue, Paul; Pan, Guoyu; Ogawa, Mina; Ogawa, Shinichiro; Na, Jie; Zhang, Peilin; Hui, Lijian; Yin, Hao; Chen, Luonan; Xu, Cheng‐Ran; Cheng, Xin

Year: 2020

Venue: Cell Reports

DOI: https://doi.org/10.1016/j.celrep.2020.108455

Paper DOT1L and Histone H3 Lysine79 Methylation as a Therapeutic Target in Mixed Lineage Leukemia.

Bernt, Kathrin M.; Faber, Jörg; Davis, Tina et al. · 2009 · Blood · DOI

Full title: DOT1L and Histone H3 Lysine79 Methylation as a Therapeutic Target in Mixed Lineage Leukemia.

Authors: Bernt, Kathrin M.; Faber, Jörg; Davis, Tina; Kung, Andrew L.; Armstrong, Scott A.

Year: 2009

Venue: Blood

DOI: https://doi.org/10.1182/blood.v114.22.212.212

Thesis Development of high throughput organ-on-chip assay incorporating 3D bioprinting technology for disease modeling studies

Lokadjaja, Matheus Calvin · 2024 · Nanyang Technological University (NTU) · DOI

Full title: Development of high throughput organ-on-chip assay incorporating 3D bioprinting technology for disease modeling studies

Authors: Lokadjaja, Matheus Calvin

Year: 2024

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/176110

Thesis Microfluidic lung-on-a-chip for assessment of naonotoxicity

Tan, Fei Yang · 2021 · Nanyang Technological University (NTU) · DOI

Full title: Microfluidic lung-on-a-chip for assessment of naonotoxicity

Authors: Tan, Fei Yang

Year: 2021

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/148016

Thesis Veterinary applications of induced pluripotent stem cells: Regenerative medicine and models for disease?

Cebrian-Serrano, A.; Stout, T.A.E.; Dinnyes, A. · 2013 · Utrecht University · DOI

Full title: Veterinary applications of induced pluripotent stem cells: Regenerative medicine and models for disease?

Authors: Cebrian-Serrano, A.; Stout, T.A.E.; Dinnyes, A.

Year: 2013

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/291255

Thesis Biokinetics in repeated-dosing in vitro drug toxicity studies

Kramer, Nynke I; Di Consiglio, Emma; Blaauboer, Bas J et al. · 2015 · Utrecht University · DOI

Full title: Biokinetics in repeated-dosing in vitro drug toxicity studies

Authors: Kramer, Nynke I; Di Consiglio, Emma; Blaauboer, Bas J; Testai, Emanuela

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/329909

Thesis Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori

Bartfeld, Sina; Clevers, Hans · 2015 · Utrecht University · DOI

Full title: Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori

Authors: Bartfeld, Sina; Clevers, Hans

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/333209

Thesis A bioassay using intestinal organoids to measure CFTR modulators in human plasma

Dekkers, R; Vijftigschild, L A W; Vonk, A M et al. · 2015 · Utrecht University · DOI

Full title: A bioassay using intestinal organoids to measure CFTR modulators in human plasma

Authors: Dekkers, R; Vijftigschild, L A W; Vonk, A M; Kruisselbrink, E; de Winter-de Groot, K M; Janssens, H M; van der Ent, C K; Beekman, J M; van der Ent, CK

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/332427

Thesis Prospective derivation of a living organoid biobank of colorectal cancer patients

van de Wetering, Marc; Francies, Hayley E; Francis, Joshua M et al. · 2015 · Utrecht University · DOI

Full title: Prospective derivation of a living organoid biobank of colorectal cancer patients

Authors: van de Wetering, Marc; Francies, Hayley E; Francis, Joshua M; Bounova, Gergana; Iorio, Francesco; Pronk, Apollo; van Houdt, Winan; van Gorp, Joost; Taylor-Weiner, Amaro; Kester, Lennart; McLaren-Douglas, Anne; Blokker, Joyce; Jaksani, Sridevi; Bartfeld, Sina; Volckman, Richard; van Sluis, Peter; Li, Vivian S W; Seepo, Sara; Sekhar Pedamallu, Chandra; Cibulskis, Kristian; Carter, Scott L; McKenna, Aaron; Lawrence, Michael S; Lichtenstein, Lee; Stewart, Chip; Koster, Jan; Versteeg, Rogier; van Oudenaarden, Alexander; Saez-Rodriguez, Julio; Vries, Robert G J; Getz, Gad; Wessels, Lodewyk; Stratton, Michael R; McDermott, Ultan; Meyerson, Matthew; Garnett, Mathew J; Clevers, Hans

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/333261

Thesis Functional characterization of cholera toxin inhibitors using human intestinal organoids

Zomer-van Ommen, Domenique D.; Pukin, Aliaksei V.; Fu, Ou et al. · 2016 · Utrecht University · DOI

Full title: Functional characterization of cholera toxin inhibitors using human intestinal organoids

Authors: Zomer-van Ommen, Domenique D.; Pukin, Aliaksei V.; Fu, Ou; Quarles Van Ufford, Linda H C; Janssens, Hettie M.; Beekman, Jeffrey M.; Pieters, Roland J.

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/343610

Thesis A 2015 focus on preventing drug-induced arrhythmias

Bossu, A; van der Heyden, MAG; de Boer, T P et al. · 2016 · Utrecht University · DOI

Full title: A 2015 focus on preventing drug-induced arrhythmias

Authors: Bossu, A; van der Heyden, MAG; de Boer, T P; Vos, M A

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/343331

Thesis Intestinal organoids and personalized medicine in cystic fibrosis: A successful patient-oriented research collaboration

Noordhoek, Jacquelien; Gulmans, Vincent; van der Ent, Kors et al. · 2016 · Utrecht University · DOI

Full title: Intestinal organoids and personalized medicine in cystic fibrosis: A successful patient-oriented research collaboration

Authors: Noordhoek, Jacquelien; Gulmans, Vincent; van der Ent, Kors; Beekman, Jeffrey M.

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/344862

Thesis 3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates

Vrij, E. J.; Espinoza, S.; Heilig, M. et al. · 2016 · Utrecht University · DOI

Full title: 3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates

Authors: Vrij, E. J.; Espinoza, S.; Heilig, M.; Kolew, A.; Schneider, M.; Van Blitterswijk, C. A.; Truckenmüller, R. K.; Rivron, N. C.

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/346663

Thesis Converging biofabrication and organoid technologies: The next frontier in hepatic and intestinal tissue engineering?

Schneeberger, Kerstin; Spee, Bart; Costa, Pedro et al. · 2017 · Utrecht University · DOI

Full title: Converging biofabrication and organoid technologies: The next frontier in hepatic and intestinal tissue engineering?

Authors: Schneeberger, Kerstin; Spee, Bart; Costa, Pedro; Sachs, Norman; Clevers, Hans; Malda, Jos

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/355491

Thesis Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

Broutier, Laura; Andersson-Rolf, Amanda; Hindley, Christopher J. et al. · 2016 · Utrecht University · DOI

Full title: Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

Authors: Broutier, Laura; Andersson-Rolf, Amanda; Hindley, Christopher J.; Boj, Sylvia F.; Clevers, Hans; Koo, Bon Kyoung; Huch, Meritxell

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/355539

Thesis Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J et al. · 2016 · Utrecht University · DOI

Full title: Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Authors: Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J; Kasteel, Emma E J; Hondebrink, Laura; Westerink, Remco H S

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/345448

Thesis Growth factors and hepatic progenitor cells in liver regeneration: translating bench to bedside

Kruitwagen, H.S. · 2017 · Utrecht University · DOI

Full title: Growth factors and hepatic progenitor cells in liver regeneration: translating bench to bedside

Authors: Kruitwagen, H.S.

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/357832

Thesis Functional characterization of cholera toxin inhibitors using human intestinal organoids

Zomer-Van Ommen, Domenique D.; Pukin, Aliaksei V.; Fu, Ou et al. · 2016 · Utrecht University · DOI

Full title: Functional characterization of cholera toxin inhibitors using human intestinal organoids

Authors: Zomer-Van Ommen, Domenique D.; Pukin, Aliaksei V.; Fu, Ou; Quarles Van Ufford, Linda H C; Janssens, Hettie M.; Beekman, Jeffrey M.; Pieters, Roland J.

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/346777

Thesis Human tissues in a dish: The research and ethical implications of organoid technology

Bredenoord, Annelien L.; Clevers, Hans; Knoblich, Juergen A. · 2017 · Utrecht University · DOI

Full title: Human tissues in a dish: The research and ethical implications of organoid technology

Authors: Bredenoord, Annelien L.; Clevers, Hans; Knoblich, Juergen A.

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/349626

Thesis Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells

Bruens, Lotte; Snippert, Hugo J.G. · 2017 · Utrecht University · DOI

Full title: Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells

Authors: Bruens, Lotte; Snippert, Hugo J.G.

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/361552

Thesis Disease Modeling in Stem Cell-Derived 3D Organoid Systems

Dutta, Devanjali; Heo, Inha; Clevers, Hans · 2017 · Utrecht University · DOI

Full title: Disease Modeling in Stem Cell-Derived 3D Organoid Systems

Authors: Dutta, Devanjali; Heo, Inha; Clevers, Hans

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/361434

Thesis Stem cell-derived organoids and their application for medical research and patient treatment

Bartfeld, Sina; Clevers, Hans · 2017 · Utrecht University · DOI

Full title: Stem cell-derived organoids and their application for medical research and patient treatment

Authors: Bartfeld, Sina; Clevers, Hans

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/361432

Thesis Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

Hu, Huili; Gehart, Helmuth; Artegiani, Benedetta et al. · 2018 · Utrecht University · DOI

Full title: Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

Authors: Hu, Huili; Gehart, Helmuth; Artegiani, Benedetta; LÖpez-Iglesias, Carmen; Dekkers, Florijn; Basak, Onur; van Es, Johan; Chuva de Sousa Lopes, Susana M.; Begthel, Harry; Korving, Jeroen; van den Born, Maaike; Zou, Chenhui; Quirk, Corrine; Chiriboga, Luis; Rice, Charles M.; Ma, Stephanie; Rios, Anne; Peters, Peter J.; de Jong, Ype P.; Clevers, Hans

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/375822

Thesis Modelling Cryptosporidium infection in human small intestinal and lung organoids

Heo, Inha; Dutta, Devanjali; Schaefer, Deborah A. et al. · 2018 · Utrecht University · DOI

Full title: Modelling Cryptosporidium infection in human small intestinal and lung organoids

Authors: Heo, Inha; Dutta, Devanjali; Schaefer, Deborah A.; Iakobachvili, Nino; Artegiani, Benedetta; Sachs, Norman; Boonekamp, Kim E.; Bowden, Gregory; Hendrickx, Antoni P.A.; Willems, Robert J.L.; Peters, Peter J.; Riggs, Michael W.; O'Connor, Roberta; Clevers, Hans

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/366895

Thesis A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Sachs, Norman; de Ligt, Joep; Kopper, Oded et al. · 2018 · Utrecht University · DOI

Full title: A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Authors: Sachs, Norman; de Ligt, Joep; Kopper, Oded; Gogola, Ewa; Bounova, Gergana; Weeber, Fleur; Balgobind, Anjali Vanita; Wind, Karin; Gracanin, Ana; Begthel, Harry; Korving, Jeroen; van Boxtel, Ruben; Duarte, Alexandra Alves; Lelieveld, Daphne; van Hoeck, Arne; Ernst, Robert Frans; Blokzijl, Francis; Nijman, Isaac Johannes; Hoogstraat, Marlous; van de Ven, Marieke; Egan, David Anthony; Zinzalla, Vittoria; Moll, Jurgen; Boj, Sylvia Fernandez; Voest, Emile Eugene; Wessels, Lodewyk; van Diest, Paul Joannes; Rottenberg, Sven; Vries, Robert Gerhardus Jacob; Cuppen, Edwin; Clevers, Hans

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/363752

Thesis Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Kruitwagen, Hedwig S.; Oosterhoff, Loes A.; Vernooij, Ingrid G W H et al. · 2017 · Utrecht University · DOI

Full title: Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Authors: Kruitwagen, Hedwig S.; Oosterhoff, Loes A.; Vernooij, Ingrid G W H; Schrall, Ingrid M.; van Wolferen, Monique E.; Bannink, Farah; Roesch, Camille; van Uden, Lisa; Molenaar, Martijn R.; Helms, J. Bernd; Grinwis, Guy C.M.; Verstegen, Monique M A; van der Laan, Luc J W; Huch, Meritxell; Geijsen, Niels; Vries, Robert R G; Clevers, Hans; Rothuizen, Jan; Schotanus, Baukje A.; Penning, Louis C.; Spee, Bart

Year: 2017

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/361008

Thesis An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, Oded; de Witte, Chris J; Lõhmussaar, Kadi et al. · 2019 · Utrecht University · DOI

Full title: An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Authors: Kopper, Oded; de Witte, Chris J; Lõhmussaar, Kadi; Valle-Inclan, Jose Espejo; Hami, Nizar; Kester, Lennart; Balgobind, Anjali Vanita; Korving, Jeroen; Proost, Natalie; Begthel, Harry; van Wijk, Lise M; Revilla, Sonia Aristín; Theeuwsen, Rebecca; van de Ven, Marieke; van Roosmalen, Markus J; Ponsioen, Bas; Ho, Victor W H; Neel, Benjamin G; Bosse, Tjalling; Gaarenstroom, Katja N; Vrieling, Harry; Vreeswijk, Maaike P G; van Diest, Paul J; Witteveen, Petronella O; Jonges, Trudy; Bos, Johannes L; van Oudenaarden, Alexander; Zweemer, Ronald P; Snippert, Hugo J G; Kloosterman, Wigard P; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/382958

Thesis Intestinal organoids to model cystic fibrosis

Van Mourik, Peter; Beekman, Jeffrey M.; Van Der Ent, Cornelis K. · 2019 · Utrecht University · DOI

Full title: Intestinal organoids to model cystic fibrosis

Authors: Van Mourik, Peter; Beekman, Jeffrey M.; Van Der Ent, Cornelis K.

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392250

Thesis Oral mucosal organoids as a potential platform for personalized cancer therapy

Driehuis, Else; Kolders, Sigrid; Spelier, Sacha et al. · 2019 · Utrecht University · DOI

Full title: Oral mucosal organoids as a potential platform for personalized cancer therapy

Authors: Driehuis, Else; Kolders, Sigrid; Spelier, Sacha; Lõhmussaar, Kadi; Willems, Stefan M.; Devriese, Lot A.; de Bree, Remco; de Ruiter, Emma J.; Korving, Jeroen; Begthel, Harry; van Es, Johan H.; Geurts, Veerle; He, Gui Wei; van Jaarsveld, Richard H.; Oka, Rurika; Muraro, Mauro J.; Vivié, Judith; Zandvliet, Maurice M.J.M.; Hendrickx, Antoni P.A.; Iakobachvili, Nino; Sridevi, Priya; Kranenburg, Onno; van Boxtel, Ruben; Kops, Geert J.P.L.; Tuveson, David A.; Peters, Peter J.; van Oudenaarden, Alexander; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/388518

Thesis Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids

Fujii, Masayuki; Clevers, Hans; Sato, Toshiro · 2019 · Utrecht University · DOI

Full title: Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids

Authors: Fujii, Masayuki; Clevers, Hans; Sato, Toshiro

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392273

Thesis Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Dutta, Devanjali; Heo, Inha; O'Connor, Roberta · 2019 · Utrecht University · DOI

Full title: Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Authors: Dutta, Devanjali; Heo, Inha; O'Connor, Roberta

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392488

Thesis Cancer modeling meets human organoid technology

Tuveson, David; Clevers, Hans · 2019 · Utrecht University · DOI

Full title: Cancer modeling meets human organoid technology

Authors: Tuveson, David; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392280

Thesis Organoids: Avatars for Personalized Medicine

Clevers, Hans C. · 2019 · Utrecht University · DOI

Full title: Organoids: Avatars for Personalized Medicine

Authors: Clevers, Hans C.

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392271

Thesis 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications

Lauschke, Volker M.; Shafagh, Reza Z.; Hendriks, Delilah F.G. et al. · 2019 · Utrecht University · DOI

Full title: 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications

Authors: Lauschke, Volker M.; Shafagh, Reza Z.; Hendriks, Delilah F.G.; Ingelman-Sundberg, Magnus

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392284

Thesis Oral mucosal organoids as a potential platform for personalized cancer therapy

Driehuis, Else; Kolders, Sigrid; Spelier, Sacha et al. · 2019 · Utrecht University · DOI

Full title: Oral mucosal organoids as a potential platform for personalized cancer therapy

Authors: Driehuis, Else; Kolders, Sigrid; Spelier, Sacha; Lohmussaar, Kadi; Willems, Stefan M; Devriese, Lot A; de Bree, Remco; de Ruiter, Emma J; Korving, Jeroen; Begthel, Harry; Van Es, Johan H; Geurts, Veerle; He, Gui-Wei; van Jaarsveld, Richard H; Oka, Rurika; Muraro, Mauro J; Vivie, Judith; Zandvliet, Maurice M J M; Hendrickx, Antoni P A; Iakobachvili, Nino; Sridevi, Priya; Kranenburg, Onno; van Boxtel, Ruben; Kops, Geert J P L; Tuveson, David A; Peters, Peter J; van Oudenaarden, Alexander; Clevers, Hans

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/389995

Thesis LifeTime and improving European healthcare through cell-based interceptive medicine

LifeTime Community Working Groups; Clevers, Hans; Scheltema, R.A. et al. · 2020 · Utrecht University · DOI

Full title: LifeTime and improving European healthcare through cell-based interceptive medicine

Authors: LifeTime Community Working Groups; Clevers, Hans; Scheltema, R.A.; van Oudenaarden, Alexander

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/409570

Thesis Biomimetic models of the glomerulus

Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P. et al. · 2022 · Utrecht University · DOI

Full title: Biomimetic models of the glomerulus

Authors: Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P.; Cervantes, Ernesto; Li, Vanessa Y.; Bonventre, Joseph V.; Masereeuw, Rosalinde; Zhang, Yu Shrike

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/417968

Thesis A systematic review of in vitro models of drug-induced kidney injury

Irvine, Alasdair R.; van Berlo, Damiën; Shekhani, Rawan et al. · 2021 · Utrecht University · DOI

Full title: A systematic review of in vitro models of drug-induced kidney injury

Authors: Irvine, Alasdair R.; van Berlo, Damiën; Shekhani, Rawan; Masereeuw, Rosalinde

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/412725

Thesis Liver organoids: Updates on disease modeling and biomedical applications

Caiazza, Carmen; Parisi, Silvia; Caiazzo, Massimiliano · 2021 · Utrecht University · DOI

Full title: Liver organoids: Updates on disease modeling and biomedical applications

Authors: Caiazza, Carmen; Parisi, Silvia; Caiazzo, Massimiliano

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/413105

Thesis Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Amatngalim, Gimano D; Rodenburg, Lisa W; Aalbers, Bente L et al. · 2022 · Utrecht University · DOI

Full title: Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/425770

Thesis Engineering a perfusable 3D human liver platform from iPS cells

· 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Engineering a perfusable 3D human liver platform from iPS cells

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/132166

Thesis Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

Griffith, Linda G; Trapecar, Martin · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

Authors: Griffith, Linda G; Trapecar, Martin

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/133522.2

Thesis Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Schepers, Arnout G; Shan, Jing; Cox, Andrew G et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Authors: Schepers, Arnout G; Shan, Jing; Cox, Andrew G; Huang, Ada; Evans, Helen; Walesky, Chad; Fleming, Heather E; Goessling, Wolfram; Bhatia, Sangeeta N

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/142801.2

Thesis Real-time bioimpedance measurements of stem cellbased disease models-on-a-chip

Gamal, Wesam · 2017 · The University of Edinburgh · DOI

Full title: Real-time bioimpedance measurements of stem cellbased disease models-on-a-chip

Authors: Gamal, Wesam

Year: 2017

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/20444

Thesis Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Tong, Zhixiang; Martyn, Keir; Yang, Andy et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Authors: Tong, Zhixiang; Martyn, Keir; Yang, Andy; Yin, Xiaolei; Mead, Benjamin E; Joshi, Nitin; Sherman, Nicholas E; Langer, Robert S; Karp, Jeffrey M

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/134688

Thesis Growth of Epithelial Organoids in a Defined Hydrogel

Broguiere, N; Isenmann, L; Hirt, C et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Growth of Epithelial Organoids in a Defined Hydrogel

Authors: Broguiere, N; Isenmann, L; Hirt, C; Ringel, T; Placzek, S; Cavalli, E; Ringnalda, F; Villiger, L; Züllig, R; Lehmann, R; Rogler, G; Heim, MH; Schüler, J; Zenobi-Wong, M; Schwank, G

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/40868

Thesis Development of novel in vitro platforms to model the lung

Kumar, Vardhman · 2022 · Duke University · DOI

Full title: Development of novel in vitro platforms to model the lung

Authors: Kumar, Vardhman

Year: 2022

Venue: Duke University

DOI: https://hdl.handle.net/10161/25793

Thesis Human Vascular Microphysiological Systems for Drug Screening

Fernandez, Cristina Elena · 2017 · Duke University · DOI

Full title: Human Vascular Microphysiological Systems for Drug Screening

Authors: Fernandez, Cristina Elena

Year: 2017

Venue: Duke University

DOI: https://hdl.handle.net/10161/13367

Thesis Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate

Krattiger, Lisa A.; Mitsi, Maria; Simona, Benjamin R. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate

Authors: Krattiger, Lisa A.; Mitsi, Maria; Simona, Benjamin R.; Ehrbar, Martin

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/198503

Thesis The development of a novel in vitro model of human liver for the study of disease pathogenesis

Chen, Liqiong · 2010 · University of Nottingham · DOI

Full title: The development of a novel in vitro model of human liver for the study of disease pathogenesis

Authors: Chen, Liqiong

Year: 2010

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/11020/1/liqiong_chen_thesis_PDF.pdf

Thesis Improving the maturation of human pluripotent stem cell - derived hepatocyte-like cells using an automated-design of experiments approach

Fotopoulos, Lazaros · 2019 · University of Nottingham · DOI

Full title: Improving the maturation of human pluripotent stem cell - derived hepatocyte-like cells using an automated-design of experiments approach

Authors: Fotopoulos, Lazaros

Year: 2019

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/56775/1/Lazaros%20Fotopoulos%20-%20Final%20PhD.pdf

Thesis Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail

Berger, B.; Donzelli, M.; Maseneni, S. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail

Authors: Berger, B.; Donzelli, M.; Maseneni, S.; Boess, F.; Roth, A.; Krahenbuhl, S.; Haschke, M.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/33523

Thesis The development of human primary hepatocyte model for investigating the pathogenesis of the hepatitis C virus

Dexter, Laura Joanne · 2010 · University of Nottingham · DOI

Full title: The development of human primary hepatocyte model for investigating the pathogenesis of the hepatitis C virus

Authors: Dexter, Laura Joanne

Year: 2010

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/12510/1/523040.pdf

Thesis Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities

Firth, Karl · 2017 · University of Nottingham · DOI

Full title: Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities

Authors: Firth, Karl

Year: 2017

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/42062/1/Thesis%20with%20corrections.pdf

Thesis Development of an in-vitro epithelial-myofibroblast intestinal model

Patient, J.D. · 2016 · University of Nottingham · DOI

Full title: Development of an in-vitro epithelial-myofibroblast intestinal model

Authors: Patient, J.D.

Year: 2016

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/33617/1/JPatient%20Thesis%20%202016.pdf

Thesis Automation and scale-up of human induced pluripotent stem cell models of cardiovascular disease for drug screening

Crutchley, James E.B. · 2016 · University of Nottingham · DOI

Full title: Automation and scale-up of human induced pluripotent stem cell models of cardiovascular disease for drug screening

Authors: Crutchley, James E.B.

Year: 2016

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/32207/1/James%20Crutchley%20Thesis%20With%20Corrections.pdf

Thesis Characterization of human stem cell-derived hepatocytes

Abukunna, Fatima · 2018 · University of Nottingham · DOI

Full title: Characterization of human stem cell-derived hepatocytes

Authors: Abukunna, Fatima

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/50524/1/Abukunna%20Fatima%20PhD%20Thesis%20ID%204212436.pdf

Thesis Developing a chemically defined, xeno-free platform to differentiate human induced pluripotent stem cells to type 2 alveolar epithelial cells of the lung

Reed, Liam · 2024 · University of Nottingham · DOI

Full title: Developing a chemically defined, xeno-free platform to differentiate human induced pluripotent stem cells to type 2 alveolar epithelial cells of the lung

Authors: Reed, Liam

Year: 2024

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/77961/1/Thesis%20revisions%20final.pdf

Thesis Modelling lymphangioleiomyomatosis (LAM) using two-dimensional and three-dimensional in vitro co-culture systems

Dongre, Arundhati · 2018 · University of Nottingham · DOI

Full title: Modelling lymphangioleiomyomatosis (LAM) using two-dimensional and three-dimensional in vitro co-culture systems

Authors: Dongre, Arundhati

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/50037/1/Arundhati%20Dongre_Thesis%20Final%20Jan%202018.pdf

Thesis Production of a sustainable primary airway cell model for respiratory research

O'Loughlin, Jonathan · 2018 · University of Nottingham · DOI

Full title: Production of a sustainable primary airway cell model for respiratory research

Authors: O'Loughlin, Jonathan

Year: 2018

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/49344/1/Jonathan%20O%27Loughlin-4289920-MRes%20Thesis.pdf

Thesis Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing

Katili, Puspita Anggraini · 2020 · University of Nottingham · DOI

Full title: Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing

Authors: Katili, Puspita Anggraini

Year: 2020

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/60613/1/Thesis_Puspita%20Anggraini%20Katili_4255054_FINAL.pdf

Thesis Studying colon cancer using intestinal organoid models for anticancer drug and gene functional analysis

Kashfi, Seyed Mohammad Hossein · 2020 · University of Nottingham · DOI

Full title: Studying colon cancer using intestinal organoid models for anticancer drug and gene functional analysis

Authors: Kashfi, Seyed Mohammad Hossein

Year: 2020

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/63073/1/Studying%20Colon%20Cancer%20Using%20Intestinal%20Organoid%20Models%20for%20Anticancer%20Drug%20and%20Gene%20Functional%20Analysis.pdf

Thesis Genetic screens in intestinal organoid (mini-gut) culture using CRISPR-Cas-9 System and studying the role of FBXL5 in colorectal cancer cells

Jinks, Nicholas · 2022 · University of Nottingham · DOI

Full title: Genetic screens in intestinal organoid (mini-gut) culture using CRISPR-Cas-9 System and studying the role of FBXL5 in colorectal cancer cells

Authors: Jinks, Nicholas

Year: 2022

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/68697/1/NJ%20Thesis%20corrected%20vesion%201%2014-3.pdf

Thesis Improved predictive models for pre-clinical drug toxicity studies

Navarro-Zornoza, Maria Dolores · 2017 · The University of Edinburgh · DOI

Full title: Improved predictive models for pre-clinical drug toxicity studies

Authors: Navarro-Zornoza, Maria Dolores

Year: 2017

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/21682

Thesis Engineering functional kidney tissue using human iPS cells

Elhendawi, Mona Mohamed Mostafa Elsaeed · 2020 · The University of Edinburgh · DOI

Full title: Engineering functional kidney tissue using human iPS cells

Authors: Elhendawi, Mona Mohamed Mostafa Elsaeed

Year: 2020

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/36843

Thesis Production of canine hepatocyte-like cells from stem cell sources

Gow, Adam George · 2015 · The University of Edinburgh · DOI

Full title: Production of canine hepatocyte-like cells from stem cell sources

Authors: Gow, Adam George

Year: 2015

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/10057

Thesis Formulating an improved in vitro hepatic model for drug development and toxicity testing

Morgan, Frances Katie · 2019 · The University of Edinburgh · DOI

Full title: Formulating an improved in vitro hepatic model for drug development and toxicity testing

Authors: Morgan, Frances Katie

Year: 2019

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/35899

Thesis Establishment of horse blood-brain barrier model for the study of drug delivery to the brain

Gupta, Gaurav · 2025 · University of Nottingham · DOI

Full title: Establishment of horse blood-brain barrier model for the study of drug delivery to the brain

Authors: Gupta, Gaurav

Year: 2025

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/80798/1/Thesis%20Gaurav%20Gupta%20Final.pdf

Thesis Development of a human induced pluripotent stem cells (hiPSCs)-derived, universal platform, for generation of immunocompetent multi-tissue organoids

Azis, Rizal · 2024 · University of Nottingham · DOI

Full title: Development of a human induced pluripotent stem cells (hiPSCs)-derived, universal platform, for generation of immunocompetent multi-tissue organoids

Authors: Azis, Rizal

Year: 2024

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/79975/1/Rizal%20Azis_PhD%20Thesis_Complete%20Chapter%201-6%20-%20Correction_edited%2020241101.pdf

Thesis Development of multiparametric kinetic data and analytics workflows for the generation of an hiPSC-cardiomyocyte based cardiovascular model

Raniga, Kavita · 2024 · University of Nottingham · DOI

Full title: Development of multiparametric kinetic data and analytics workflows for the generation of an hiPSC-cardiomyocyte based cardiovascular model

Authors: Raniga, Kavita

Year: 2024

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/77502/1/Thesis_Combined_Revised_010324_KR.pdf

Thesis Development of a high-throughput drug screening platform for oligodendrocyte myelination (for progressive multiple sclerosis)

Kim, Jee Soo · 2020 · The University of Edinburgh · DOI

Full title: Development of a high-throughput drug screening platform for oligodendrocyte myelination (for progressive multiple sclerosis)

Authors: Kim, Jee Soo

Year: 2020

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/37070

Thesis Drug risk assessment and repurposing using biomimetic chromatography and body-on-chip technology

Carr, Liam · 2024 · The University of Edinburgh · DOI

Full title: Drug risk assessment and repurposing using biomimetic chromatography and body-on-chip technology

Authors: Carr, Liam

Year: 2024

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/42703

Thesis Advancing In Vitro Tissue Modeling through Bioprinted Biomaterial Platforms

Lu, Ting-Yu · 2025 · University of California, San Diego (UCSD) · DOI

Full title: Advancing In Vitro Tissue Modeling through Bioprinted Biomaterial Platforms

Authors: Lu, Ting-Yu

Year: 2025

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/3ff843tg

Thesis Placenta Mesenchymal Stem Cell (PMSC) Potency Assay Development in 96-well Format

Bui, Nghia Dinh · 2023 · University of California, Davis · DOI

Full title: Placenta Mesenchymal Stem Cell (PMSC) Potency Assay Development in 96-well Format

Authors: Bui, Nghia Dinh

Year: 2023

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/6gh2c5mf

Thesis The Development and Assessment of a 3-D Bone-On-A-Chip Device

Bahmaee, Hossein · 2019 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: The Development and Assessment of a 3-D Bone-On-A-Chip Device

Authors: Bahmaee, Hossein

Year: 2019

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/24788/1/Thesis%20complete-%20Final%20WhiteRose-Hossein%20Bahmaee.docx

Thesis Establishment and validation of organ-on-chip models for Inflammatory Bowel Disease modelling in vitro

Kosim, Kinga · 2021 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Establishment and validation of organ-on-chip models for Inflammatory Bowel Disease modelling in vitro

Authors: Kosim, Kinga

Year: 2021

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: oai:etheses.whiterose.ac.uk:28964

Thesis Towards more reliable in vitro drug testing for head and neck squamous cell carcinoma via a human tumor–derived matrix

Tuomainen, Katja · 2021 · University of Helsinki (HELDA) · DOI

Full title: Towards more reliable in vitro drug testing for head and neck squamous cell carcinoma via a human tumor–derived matrix

Authors: Tuomainen, Katja

Year: 2021

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/336649

Thesis Development of high throughput microfluidic gut-on-a-chip models for drug discovery and target validation in inflammatory bowel disease

Beaurivage, Claudia · 2020 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Development of high throughput microfluidic gut-on-a-chip models for drug discovery and target validation in inflammatory bowel disease

Authors: Beaurivage, Claudia

Year: 2020

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: oai:etheses.whiterose.ac.uk:29094

Thesis Development of organotypic liver cell cultures in three-dimensional biomaterial hydrogels

Malinen, Melina · 2014 · University of Helsinki (HELDA) · DOI

Full title: Development of organotypic liver cell cultures in three-dimensional biomaterial hydrogels

Authors: Malinen, Melina

Year: 2014

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/135643

Thesis Organoid models: the future companions of personalized drug development

Piraino, Francesco; Costa, Mariana; Meyer, Marine et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Organoid models: the future companions of personalized drug development

Authors: Piraino, Francesco; Costa, Mariana; Meyer, Marine; Cornish, Georgina; Ceroni, Camilla; Garnier, Virginie; Hoehnel-Ka, Sylke; Brandenberg, Nathalie

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/243273

Thesis An Integrated Transcriptomic Cell Atlas of Human Endoderm-derived Organoids

Xu, Quan; Halle, Lennard; Hediyeh-zadeh, Soroor et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: An Integrated Transcriptomic Cell Atlas of Human Endoderm-derived Organoids

Authors: Xu, Quan; Halle, Lennard; Hediyeh-zadeh, Soroor; Kuijs, Merel; Riedweg, Rya; Kilik, Umut; Recaldin, Timothy; Yu, Qianhui; Rall, Isabell; Frum, Tristan; Adam, Lukas; Parikh, Shrey; Kfuri-Rubens, Raphael; Gander, Manuel; Klein, Dominik; Curion, Fabiola; He, Zhisong; Fleck, Jonas Simon; Oost, Koen; Kahnwald, Maurice; Barbiero, Silvia; Mitrofanova, Olga; Maciag, Grzegorz Jerzy; Jensen, Kim B.; Lutolf, Matthias; Liberali, Prisca; Spence, Jason R.; Gjorevski, Nikolche; Beumer, Joep; Treutlein, Barbara; Theis, Fabian J.; Camp, J. Gray

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250256

Thesis Surface Plasmon Resonance-Based Cellular Assays in Pharmaceutical Research : Interpretation of the Label-Free Signals

Suutari, Teemu · 2020 · University of Helsinki (HELDA) · DOI

Full title: Surface Plasmon Resonance-Based Cellular Assays in Pharmaceutical Research : Interpretation of the Label-Free Signals

Authors: Suutari, Teemu

Year: 2020

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/322101

Thesis Development and validation of microfluidic subcellular in vitro models for drug metabolism studies

Rautsola, Iiro · 2025 · University of Helsinki (HELDA) · DOI

Full title: Development and validation of microfluidic subcellular in vitro models for drug metabolism studies

Authors: Rautsola, Iiro

Year: 2025

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/603459

Thesis A microfluidic array for high-content screening at whole-organism resolution

Migliozzi, D.; Cornaglia, M.; Mouchiroud, L. et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A microfluidic array for high-content screening at whole-organism resolution

Authors: Migliozzi, D.; Cornaglia, M.; Mouchiroud, L.; Auwerx, J.; Gijs, M. A. M.

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/153759

Thesis High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays

Brandenberg, Nathalie; Hoehnel, Sylke; Kuttler, Fabien et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays

Authors: Brandenberg, Nathalie; Hoehnel, Sylke; Kuttler, Fabien; Homicsko, Krisztian; Ceroni, Camilla; Ringel, Till; Gjorevski, Nikolce; Schwank, Gerald; Coukos, George; Turcatti, Gerardo; Lutolf, Matthias P.

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/169563

Thesis Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism - Update to the Human Model and Expansion of Applications.

Zietek, Tamara; Giesbertz, Pieter; Ewers, Maren et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism - Update to the Human Model and Expansion of Applications.

Authors: Zietek, Tamara;Giesbertz, Pieter;Ewers, Maren;Reichart, Florian;Weinmüller, Michael;Urbauer, Elisabeth;Haller, Dirk;Demir, Ihsan Ekin;Ceyhan, Güralp O;Kessler, Horst;Rath, Eva

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1617207

Thesis A patient-derived motor platform for diagnostics and drug discovery in neuromuscular diseases : a dissertation presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry, Massey University, Manawatū, New Zealand. EMBARGOED to 7 May 2027.

Burling, Sophie · 2025 · Massey University · DOI

Full title: A patient-derived motor platform for diagnostics and drug discovery in neuromuscular diseases : a dissertation presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry, Massey University, Manawatū, New Zealand. EMBARGOED to 7 May 2027.

Authors: Burling, Sophie

Year: 2025

Venue: Massey University

DOI: https://mro.massey.ac.nz/handle/10179/72980

Thesis Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies.

Zeilinger, K; Schreiter, T; Darnell, M et al. · 2011 · Technical University of Munich (TUM) · DOI

Full title: Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies.

Authors: Zeilinger, K;Schreiter, T;Darnell, M;Söderdahl, T;Lübberstedt, M;Dillner, B;Knobeloch, D;Nüssler, AK;Gerlach, JC;Andersson, TB

Year: 2011

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587595

Thesis CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions.

Hultquist, Judd F; Hiatt, Joseph; Schumann, Kathrin et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions.

Authors: Hultquist, Judd F;Hiatt, Joseph;Schumann, Kathrin;McGregor, Michael J;Roth, Theodore L;Haas, Paige;Doudna, Jennifer A;Marson, Alexander;Krogan, Nevan J

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590624

Thesis Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Ladel, Simone; Schlossbauer, Patrick; Flamm, Johannes et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Authors: Ladel, Simone;Schlossbauer, Patrick;Flamm, Johannes;Luksch, Harald;Mizaikoff, Boris;Schindowski, Katharina

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1591584

Thesis ENGINEERING STEM CELLS AND ORGANOIDS ON A CHIP FOR THE STUDY OF HUMAN HEALTH AND DISEASE

Park, Sunghee · 2023 · University of Pennsylvania · DOI

Full title: ENGINEERING STEM CELLS AND ORGANOIDS ON A CHIP FOR THE STUDY OF HUMAN HEALTH AND DISEASE

Authors: Park, Sunghee

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/59234

Thesis Development of in vitro Drug Screening Platforms Using Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

Kurokawa, Yosuke · 2017 · Washington University in St. Louis · DOI

Full title: Development of in vitro Drug Screening Platforms Using Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

Authors: Kurokawa, Yosuke

Year: 2017

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/eng_etds/284

Thesis Normothermic machine perfused organs as models of drug pharmacokinetics and therapeutic delivery

Clark, TL · 2022 · University of Oxford - ORA · DOI

Full title: Normothermic machine perfused organs as models of drug pharmacokinetics and therapeutic delivery

Authors: Clark, TL

Year: 2022

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:1b1665f8-7d67-45b2-a3ce-4fcc5bfcb18f

Thesis 3D induced-pluripotent stem cell model of metabolic heart diseases for drug discovery and disease modelling

Purnama, U · 2022 · University of Oxford - ORA · DOI

Full title: 3D induced-pluripotent stem cell model of metabolic heart diseases for drug discovery and disease modelling

Authors: Purnama, U

Year: 2022

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:c2b47c73-0049-4fc9-9a25-92e9b840271d

Thesis 21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

Rahman, Luna; Williams, Andrew; Gelda, Krishna et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: 21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

Authors: Rahman, Luna; Williams, Andrew; Gelda, Krishna; Nikota, Jake; Wu, Dongmei; Vogel, Ulla Birgitte; Halappanavar, Sabina

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/1f0c0c81-785d-48e3-9f5c-fa0b2ff9396c

Thesis Toxicogenomics Investigation Under the eTOX Project

Taboureau, Olivier; Hersey, Anne; Audouze, Karine Marie Laure et al. · 2012 · Technical University of Denmark (DTU) · DOI

Full title: Toxicogenomics Investigation Under the eTOX Project

Authors: Taboureau, Olivier; Hersey, Anne; Audouze, Karine Marie Laure; Gautier, Laurent; Jacobsen, Ulrik Plesner; Akhtar, Ruth; Atkinson, Francis; Overington, John P.; Brunak, Søren

Year: 2012

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/0cb22e78-9013-43a5-aa0f-3a0a34483d1f

Thesis Development of in-vitro models to study effects of compounds that modulate cellular functions in patients with mitochondrial disease

Lodge, T · 2016 · University of Oxford - ORA · DOI

Full title: Development of in-vitro models to study effects of compounds that modulate cellular functions in patients with mitochondrial disease

Authors: Lodge, T

Year: 2016

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:40956b41-e390-4aec-bab8-f2f313c69e09

Thesis Development of microfluidic cell culture devices towards an in vitro human intestinal barrier model

Tan, Hsih-Yin · 2015 · Technical University of Denmark (DTU) · DOI

Full title: Development of microfluidic cell culture devices towards an in vitro human intestinal barrier model

Authors: Tan, Hsih-Yin

Year: 2015

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/2e21915a-bd8a-48f6-a8fb-1882195e0b62

Thesis The European Lead Factory:Results from a decade of collaborative, public–private, drug discovery programs

van Vlijmen, Herman; Pannifer, Andrew D.; Cochrane, Phil et al. · 2024 · Technical University of Denmark (DTU) · DOI

Full title: The European Lead Factory:Results from a decade of collaborative, public–private, drug discovery programs

Authors: van Vlijmen, Herman; Pannifer, Andrew D.; Cochrane, Phil; Basting, Daniel; Li, Volkhart M.; Engkvist, Ola; Ortholand, Jean Yves; Wagener, Markus; Duffy, James; Finsinger, Dirk; Davis, Jeremy; van Helden, Steven P.; de Vlieger, Jon S.B.

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/4b41b15b-466f-422d-bd09-2df3417be528

Thesis 3D Printed Human Small Intestine Models for Drug Delivery Testing and Disease Modelling

Taebnia, Nayere; id_orcid 0000-0003-0707-278X · 2021 · Technical University of Denmark (DTU) · DOI

Full title: 3D Printed Human Small Intestine Models for Drug Delivery Testing and Disease Modelling

Authors: Taebnia, Nayere; id_orcid 0000-0003-0707-278X

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/925dcaa5-fb9f-4476-9028-ae1ce9720b2a

Thesis Quantifying the transport of biologics across intestinal barrier models in real-time by fluorescent imaging

Weller, Arjen; Hansen, Morten B.; Marie, Rodolphe et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Quantifying the transport of biologics across intestinal barrier models in real-time by fluorescent imaging

Authors: Weller, Arjen; Hansen, Morten B.; Marie, Rodolphe; id_orcid 0000-0002-8338-1990; Hundahl, Adam C.; Hempel, Casper; Kempen, Paul J.; id_orcid 0000-0003-2179-2257; Frandsen, Henrik L.; id_orcid 0000-0002-1905-8144; Parhamifar, Ladan; Larsen, Jannik B.; id_orcid 0000-0003-4754-2803; Andresen, Thomas L.; id_orcid 0000-0002-1048-127X

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/771a1080-5944-4de9-932c-98fc96d262dd

Thesis Advancing humanized 3D tumor modeling using an open access xeno-free medium

Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380; Rodriguez, Manuel Marcos et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Advancing humanized 3D tumor modeling using an open access xeno-free medium

Authors: Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380; Rodriguez, Manuel Marcos; Zór, Kinga; id_orcid 0000-0002-2905-4155; Boisen, Anja; id_orcid 0000-0002-9918-6567; Oredsson, Stina

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/e6059c98-0553-4335-b20d-958de21ca5d6

Thesis Fetal bovine serum:how to leave it behind in the pursuit of more reliable science

Weber, Tilo; Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380 et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Fetal bovine serum:how to leave it behind in the pursuit of more reliable science

Authors: Weber, Tilo; Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380; Chary, Aline; D’Alessandro, Vito; Haut, Leah; Seufert, Sebastian; Wenzel, Esther Veronika; Hickman, James; Bieback, Karen; Wiest, Joachim; Dirks, Wilhelm Gerhard; Coecke, Sandra; Oredsson, Stina

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d034d8e1-d314-4d9a-ae44-e35c407f362d

Thesis Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies

Altmaier, Saskia; Meiser, Ina; Lemesre, Emilie et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies

Authors: Altmaier, Saskia; Meiser, Ina; Lemesre, Emilie; Chanrion, Benjamin; Steeg, Rachel; Leonte, Lidia Elena; Holst, Bjørn; Nielsen, Boye Schnack; Clausen, Christian; Schmidt, Katharina; Vinggaard, Anne Marie; id_orcid 0000-0002-6822-3572; Zimmermann, Heiko; Neubauer, Julia Christiane; Rasmussen, Mikkel Aabech

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/25d17948-a3d4-4d26-a51d-f92cc7bc8f6f

Thesis Development of synthetic vasculature, 4D optical oxygen mapping and their implementation in human 3D liver tissue models

Wesseler, Milan Finn Laszlo · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Development of synthetic vasculature, 4D optical oxygen mapping and their implementation in human 3D liver tissue models

Authors: Wesseler, Milan Finn Laszlo

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/fffb3983-c5b6-4507-b249-cd9c94ffb160

Thesis Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock

Weldearegay, Yenehiwot Berhanu; Brogaard, Louise; id_orcid 0000-0003-4571-6822 et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock

Authors: Weldearegay, Yenehiwot Berhanu; Brogaard, Louise; id_orcid 0000-0003-4571-6822; Rautenschlein, Silke; Meens, Jochen; Valentin-Weigand, Peter; Schaaf, Désirée

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d38f1bcf-9098-466b-91f4-4953c7b489dd

Thesis Development of microfluidic cell culture devices towards an in vitro human intestinal barrier model

Tan, Hsih-Yin · 2015 · Technical University of Denmark (DTU) · DOI

Full title: Development of microfluidic cell culture devices towards an in vitro human intestinal barrier model

Authors: Tan, Hsih-Yin

Year: 2015

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/2e21915a-bd8a-48f6-a8fb-1882195e0b62

Thesis Bioprinting technologies for disease modeling

Memic, Adnan; Navaei, Ali; Mirani, Bahram et al. · 2017 · Technical University of Denmark (DTU) · DOI

Full title: Bioprinting technologies for disease modeling

Authors: Memic, Adnan; Navaei, Ali; Mirani, Bahram; Cordova, Julio Alvin Vacacela; Aldhahri, Musab; Dolatshahi-Pirouz, Alireza; id_orcid 0000-0001-6326-0836; Akbari, Mohsen; Nikkhah, Mehdi

Year: 2017

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/741da80d-fac2-4489-b3ca-dd7c85ef185f

Thesis Toxicogenomics Investigation Under the eTOX Project

Taboureau, Olivier; Hersey, Anne; Audouze, Karine Marie Laure et al. · 2012 · Technical University of Denmark (DTU) · DOI

Full title: Toxicogenomics Investigation Under the eTOX Project

Authors: Taboureau, Olivier; Hersey, Anne; Audouze, Karine Marie Laure; Gautier, Laurent; Jacobsen, Ulrik Plesner; Akhtar, Ruth; Atkinson, Francis; Overington, John P.; Brunak, Søren

Year: 2012

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/0cb22e78-9013-43a5-aa0f-3a0a34483d1f

Thesis Engineering cardiac microenvironments for func onal drug safety screening

Christensen, Rie Kjær · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Engineering cardiac microenvironments for func onal drug safety screening

Authors: Christensen, Rie Kjær

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/db3fb68f-4e62-48db-9338-5b2fa320ee02

Thesis 21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

Rahman, Luna; Williams, Andrew; Gelda, Krishna et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: 21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

Authors: Rahman, Luna; Williams, Andrew; Gelda, Krishna; Nikota, Jake; Wu, Dongmei; Vogel, Ulla Birgitte; Halappanavar, Sabina

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/1f0c0c81-785d-48e3-9f5c-fa0b2ff9396c

Thesis Cardiac spheroids as promising in vitro models to study the human heart microenvironment

Polonchuk, Liudmila; Chabria, Mamta; Badi, Laura et al. · 2017 · University of Copenhagen · DOI

Full title: Cardiac spheroids as promising in vitro models to study the human heart microenvironment

Authors: Polonchuk, Liudmila; Chabria, Mamta; Badi, Laura; Hoflack, Jean-Christophe; Figtree, Gemma A; Davies, Michael J; Gentile, Carmine

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/60dcd39c-5522-4d66-a130-ccd51550a91c

Thesis Novel approaches to 3D cancer heterospheroid culture and assay development for immunotherapy screening

Madsen, Natasha Helleberg; Nielsen, Boye Schnack; Skandorff, Isabella et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Novel approaches to 3D cancer heterospheroid culture and assay development for immunotherapy screening

Authors: Madsen, Natasha Helleberg; Nielsen, Boye Schnack; Skandorff, Isabella; Rodriguez-Pardo, Carlos; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Ormhøj, Maria; Holmstrøm, Kim; Larsen, Jesper; Gad, Monika

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/37b0424d-9118-4303-a180-a90d4c4e84e6

Thesis P036 A comparative study of cell culture inserts for in vitro modeling of the cystic fibrosis airway epithelium

Lolle, S.; Hettich, A.; Colque, A. et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: P036 A comparative study of cell culture inserts for in vitro modeling of the cystic fibrosis airway epithelium

Authors: Lolle, S.; Hettich, A.; Colque, A.; Madsen, K.; Simões, F.B.; Aanæs, K.; Molin, S.; id_orcid 0000-0002-7973-2639; Johansen, H. Krogh

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/38a54c78-e220-4b1b-9148-7f9253eff5fd

Thesis Establishment of an In Vitro screening model for neurodegeneration induced by antimalarial drugs of the artemisinin-type

Schmuck, Gabriele; Haynes, Richard; id_orcid 0000-0001-8554-1823 · 2000 · Charles Sturt University - Research Output · DOI

Full title: Establishment of an In Vitro screening model for neurodegeneration induced by antimalarial drugs of the artemisinin-type

Authors: Schmuck, Gabriele; Haynes, Richard; id_orcid 0000-0001-8554-1823

Year: 2000

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/5ed37215-4bd3-48f7-9a09-9eb442d91a4c

Thesis Small intestinal epithelial cell models designed for utilizing advanced microscopic platforms to investigate transport of biopharmaceuticals

Weller, Arjen · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Small intestinal epithelial cell models designed for utilizing advanced microscopic platforms to investigate transport of biopharmaceuticals

Authors: Weller, Arjen

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/36b21136-dfa9-48f6-850b-c5720279637f

Thesis Background and Organ on a Chip

Dufva, Martin; id_orcid 0000-0001-5449-0189 · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Background and Organ on a Chip

Authors: Dufva, Martin; id_orcid 0000-0001-5449-0189

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/2035eb02-1196-4a57-babe-7113a6ed2591

Thesis Centrifugal microfluidics for cell-based assays in flow

Serioli , Laura · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Centrifugal microfluidics for cell-based assays in flow

Authors: Serioli , Laura

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d058b198-e543-43c4-a427-b80198f24f8a

Thesis Quantifying the transport of biologics across intestinal barrier models in real-time by fluorescent imaging

Weller, Arjen; Hansen, Morten B.; Marie, Rodolphe et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Quantifying the transport of biologics across intestinal barrier models in real-time by fluorescent imaging

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/771a1080-5944-4de9-932c-98fc96d262dd

Thesis Next generation human brain models: engineered flat brain organoids featuring gyrification:Note

Rothenbücher, Theresa S.P.; Gürbüz, Hakan; Pereira, Marta P. et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Next generation human brain models: engineered flat brain organoids featuring gyrification:Note

Authors: Rothenbücher, Theresa S.P.; Gürbüz, Hakan; Pereira, Marta P.; Heiskanen, Arto; id_orcid 0000-0002-7124-8420; Emnéus, Jenny; id_orcid 0000-0002-8061-201X; Martinez-Serrano, Alberto

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/8bf4090b-1d00-4826-9887-0fb17274b848

Thesis Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock

Weldearegay, Yenehiwot Berhanu; Brogaard, Louise; id_orcid 0000-0003-4571-6822 et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock

Authors: Weldearegay, Yenehiwot Berhanu; Brogaard, Louise; id_orcid 0000-0003-4571-6822; Rautenschlein, Silke; Meens, Jochen; Valentin-Weigand, Peter; Schaaf, Désirée

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d38f1bcf-9098-466b-91f4-4953c7b489dd

Thesis The central role of Wnt signaling and organoid technology in personalizing anticancer therapy

Vincan, Elizabeth; Schwab, Renate H.M.; id_orcid 0000-0002-5551-1700 et al. · 2018 · Charles Sturt University - Research Output · DOI

Full title: The central role of Wnt signaling and organoid technology in personalizing anticancer therapy

Authors: Vincan, Elizabeth; Schwab, Renate H.M.; id_orcid 0000-0002-5551-1700; Flanagan, Dustin J.; Moselen, Jean M.; Tran, Bang M.; Barker, Nick; Phesse, Toby J.

Year: 2018

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/aabde776-9321-4bbc-b868-846a9b402a23

Thesis Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture

Vivas, Aisen; IJspeert, Camilo; Pan, Jesper Yue et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture

Authors: Vivas, Aisen; IJspeert, Camilo; Pan, Jesper Yue; id_orcid 0000-0002-1953-6302; Vermeul, Kim; van den Berg, Albert; Passier, Robert; Keller, Stephan Sylvest; id_orcid 0000-0003-4108-1305; van der Meer, Andries D.

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/bb82a97f-4e87-4b9e-b674-5f8f3e2bde2e

Thesis TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY

Krewski, D.; Acosta, D.; Andersen, M. et al. · 2010 · Technical University of Denmark (DTU) · DOI

Full title: TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY

Authors: Krewski, D.; Acosta, D.; Andersen, M.; Anderson, H.; Bailar, J.C.; Boekelheide, K.; Brent, R.; Charnley, G.; Cheung, V.G.; Green, S.; Kelsey, K.T.; Kerkvliet, N.I.; Li, A.A.; McCray, L.; Meyer, Otto A.; Patterson, R.D.; Pennie, W.; Scala, R.A.; Solomon, G.M.; Stephens, M.; Yager, J.; Zeise, L.

Year: 2010

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a5cf1599-7e53-43a9-af7b-437cdfa8d4a5

Thesis Engineering cardiac microenvironments for func onal drug safety screening

Christensen, Rie Kjær · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Engineering cardiac microenvironments for func onal drug safety screening

Authors: Christensen, Rie Kjær

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/db3fb68f-4e62-48db-9338-5b2fa320ee02

Thesis The economics of manufacturing clinical-grade advanced therapy medicinal products (ATMPs)

Abou El-Enein, Mohamed · 2014 · Freie Universität Berlin (Refubium) · DOI

Full title: The economics of manufacturing clinical-grade advanced therapy medicinal products (ATMPs)

Authors: Abou El-Enein, Mohamed

Year: 2014

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/13668

Thesis 3D Printed Human Small Intestine Models for Drug Delivery Testing and Disease Modelling

Taebnia, Nayere; id_orcid 0000-0003-0707-278X · 2021 · Technical University of Denmark (DTU) · DOI

Full title: 3D Printed Human Small Intestine Models for Drug Delivery Testing and Disease Modelling

Authors: Taebnia, Nayere; id_orcid 0000-0003-0707-278X

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/925dcaa5-fb9f-4476-9028-ae1ce9720b2a

Thesis Fetal bovine serum:how to leave it behind in the pursuit of more reliable science

Weber, Tilo; Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380 et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Fetal bovine serum:how to leave it behind in the pursuit of more reliable science

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/d034d8e1-d314-4d9a-ae44-e35c407f362d

Thesis Isolierung, Charakterisierung und Kultivierung humaner Hepatozyten und nicht- parenchymaler Leberzellen für pharmakologische Untersuchungen

Pfeiffer, Elisa · 2017 · Freie Universität Berlin (Refubium) · DOI

Full title: Isolierung, Charakterisierung und Kultivierung humaner Hepatozyten und nicht- parenchymaler Leberzellen für pharmakologische Untersuchungen

Authors: Pfeiffer, Elisa

Year: 2017

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/10015

Thesis Isolation und Charakterisierung von primären humanen Leberzellen und deren Anwendung in in vivo nahen in vitro Lebermodellen

Kegel, Victoria · 2017 · Freie Universität Berlin (Refubium) · DOI

Full title: Isolation und Charakterisierung von primären humanen Leberzellen und deren Anwendung in in vivo nahen in vitro Lebermodellen

Authors: Kegel, Victoria

Year: 2017

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/3441

Thesis Characterization of organoid cultured human breast cancer

Goldhammer, Nadine; Kim, Jiyoung; Timmermans-Wielenga, Vera et al. · 2019 · University of Copenhagen · DOI

Full title: Characterization of organoid cultured human breast cancer

Authors: Goldhammer, Nadine; Kim, Jiyoung; Timmermans-Wielenga, Vera; Petersen, Ole William

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/f9bd47f3-a042-460f-a196-ddf78f5d47a3

Thesis Development of synthetic vasculature, 4D optical oxygen mapping and their implementation in human 3D liver tissue models

Wesseler, Milan Finn Laszlo · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Development of synthetic vasculature, 4D optical oxygen mapping and their implementation in human 3D liver tissue models

Authors: Wesseler, Milan Finn Laszlo

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/fffb3983-c5b6-4507-b249-cd9c94ffb160

Thesis Gastric organoids:Advancing the study of H. pylori pathogenesis and inflammation

Idowu, Sulaimon; Bertrand, Paul P.; Walduck, Anna K. et al. · 2022 · Charles Sturt University - Research Output · DOI

Full title: Gastric organoids:Advancing the study of H. pylori pathogenesis and inflammation

Authors: Idowu, Sulaimon; Bertrand, Paul P.; Walduck, Anna K.; id_orcid 0000-0002-9624-4370

Year: 2022

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/e0e2ebc0-a821-4afd-a2bd-64f137dd64da

Thesis Advancing humanized 3D tumor modeling using an open access xeno-free medium

Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380; Rodriguez, Manuel Marcos et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Advancing humanized 3D tumor modeling using an open access xeno-free medium

Authors: Malakpour-Permlid, Atena; id_orcid 0000-0002-1745-1380; Rodriguez, Manuel Marcos; Zór, Kinga; id_orcid 0000-0002-2905-4155; Boisen, Anja; id_orcid 0000-0002-9918-6567; Oredsson, Stina

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/e6059c98-0553-4335-b20d-958de21ca5d6

Thesis Development towards an organ-on-a-chip technology for complex in vitro testing of T-cell products

Durieux, Isabell · 2025 · Freie Universität Berlin (Refubium) · DOI

Full title: Development towards an organ-on-a-chip technology for complex in vitro testing of T-cell products

Authors: Durieux, Isabell

Year: 2025

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/47225

Thesis Development of a 3D in vitro model to study lung pathophysiology

Eichhorst, Anne Kirstin · 2021 · Freie Universität Berlin (Refubium) · DOI

Full title: Development of a 3D in vitro model to study lung pathophysiology

Authors: Eichhorst, Anne Kirstin

Year: 2021

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/33036

Thesis Untersuchungen zur Optimierung pharmakologischer Studien an hepatischen Zellen in 2D- und 3D-Kulturen

Lübberstedt, Marc · 2015 · Freie Universität Berlin (Refubium) · DOI

Full title: Untersuchungen zur Optimierung pharmakologischer Studien an hepatischen Zellen in 2D- und 3D-Kulturen

Authors: Lübberstedt, Marc

Year: 2015

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/6569

Thesis Development of a Reconstructed Induced Pluripotent Stem Cell - Derived Immunocompetent Skin Model

Dubau, Marla · 2025 · Freie Universität Berlin (Refubium) · DOI

Full title: Development of a Reconstructed Induced Pluripotent Stem Cell - Derived Immunocompetent Skin Model

Authors: Dubau, Marla

Year: 2025

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/48340

Thesis Modellierung der Invasion von Glioblastomen mittels Mikroskopie und Sequenzierung

Krieger, Teresa Gabriela · 2022 · Freie Universität Berlin (Refubium) · DOI

Full title: Modellierung der Invasion von Glioblastomen mittels Mikroskopie und Sequenzierung

Authors: Krieger, Teresa Gabriela

Year: 2022

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/35965

Thesis In vitro Skin Disease Equivalents and their Applications in Basic Dermatologic Research

Hönzke, Stefan · 2018 · Freie Universität Berlin (Refubium) · DOI

Full title: In vitro Skin Disease Equivalents and their Applications in Basic Dermatologic Research

Authors: Hönzke, Stefan

Year: 2018

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/6617

Thesis 3D Bioprinted Liver-on-a-Chip for Drug Cytotoxicity Screening

Huh, JunTae; Parra, Joao Paulo R.L.L. [UNESP]; Copus, Joshua S. et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: 3D Bioprinted Liver-on-a-Chip for Drug Cytotoxicity Screening

Authors: Huh, JunTae; Parra, Joao Paulo R.L.L. [UNESP]; Copus, Joshua S.; Kang, Hyun-Wook; Bishop, Colin E.; Soker, Shay; Murphy, Sean; Shupe, Thomas D.; Yoo, James J.; Lee, Sang Jin; Atala, Anthony

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1089/ten.tea.2023.0212

Thesis Historical evolution of spheroids and organoids, and possibilities of use in life sciences and medicine

Sakalem, Marna Eliana; De Sibio, Maria Teresa [UNESP]; da Costa, Felipe Allan da Silva [UNESP] et al. · 2021 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Historical evolution of spheroids and organoids, and possibilities of use in life sciences and medicine

Authors: Sakalem, Marna Eliana; De Sibio, Maria Teresa [UNESP]; da Costa, Felipe Allan da Silva [UNESP]; de Oliveira, Miriane [UNESP]

Year: 2021

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1002/biot.202000463

Thesis Kinetic Analysis of Micro-Physiological Systems Using Automated Live-Cell Imaging

Chang, Jonathan J. · 2024 · Georgia Institute of Technology · DOI

Full title: Kinetic Analysis of Micro-Physiological Systems Using Automated Live-Cell Imaging

Authors: Chang, Jonathan J.

Year: 2024

Venue: Georgia Institute of Technology

DOI: https://hdl.handle.net/1853/75106

Thesis High-throughput 3D on-chip potency assay for cell therapy products

Schneider, Rebecca S. · 2024 · Georgia Institute of Technology · DOI

Full title: High-throughput 3D on-chip potency assay for cell therapy products

Authors: Schneider, Rebecca S.

Year: 2024

Venue: Georgia Institute of Technology

DOI: https://hdl.handle.net/1853/75077

Thesis An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient Heterogeneity

Jiang, Shengwei; Zhao, Haoran; Zhang, Weijie et al. · 2020 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient Heterogeneity

Authors: Jiang, Shengwei; Zhao, Haoran; Zhang, Weijie; Wang, Jiaqi; Liu, Yuhong; Cao, Yuanxiong; Zheng, Honghui; Hu, Zhiwei; Wang, Shubin; Zhu, Yu; Wang, Wei; Cui, Shuzhong; Lobie, Peter E.; Huang, Laiqiang; Ma, Shaohua

Year: 2020

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-109307

Thesis Bioengineering of morphologically and functionally accurate in vitro intestinal models

Langer, Jakob Josef · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineering of morphologically and functionally accurate in vitro intestinal models

Authors: Langer, Jakob Josef

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/251174

Thesis Organoids as tools for fundamental discovery and translation-A Keystone Symposia report

Cable, Jennifer; Lutolf, Matthias P.; Fu, Jianping et al. · 2022 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Organoids as tools for fundamental discovery and translation-A Keystone Symposia report

Authors: Cable, Jennifer; Lutolf, Matthias P.; Fu, Jianping; Park, Sunghee Estelle; Apostolou, Athanasia; Chen, Shuibing; Song, Cheng Jack; Spence, Jason R.; Liberali, Prisca; Lancaster, Madeline; Meier, Anna B.; Pek, Nicole Min Qian; Wells, James M.; Capeling, Meghan M.; Uzquiano, Ana; Musah, Samira; Huch, Meritxell; Gouti, Mina; Hombrink, Pleun; Quadrato, Giorgia; Urenda, Jean-Paul

Year: 2022

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/191648

Thesis Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays

Simonneau, Claire; Duschmale, Martina; Gavrilov, Alina et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays

Authors: Simonneau, Claire; Duschmale, Martina; Gavrilov, Alina; Brandenberg, Nathalie; Hoehnel, Sylke; Ceroni, Camilla; Lassalle, Evodie; Kassianidou, Elena; Knoetgen, Hendrik; Niewoehner, Jens; Villasenor, Roberto

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/181973

Thesis Microarrayed human bone marrow organoids for modeling blood stem cell dynamics

Giger, Sonja; Hofer, Moritz; Miljkovic-Licina, Marijana et al. · 2022 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Microarrayed human bone marrow organoids for modeling blood stem cell dynamics

Authors: Giger, Sonja; Hofer, Moritz; Miljkovic-Licina, Marijana; Hoehnel, Sylke; Brandenberg, Nathalie; Guiet, Romain; Ehrbar, Martin; Kleiner, Esther; Gegenschatz-Schmid, Katharina; Matthes, Thomas; Lutolf, Matthias P.

Year: 2022

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/189333

Thesis Cell bead based three-dimensional (3D) hepatic model toward high throughput drug-induced toxicity screening

Brandenberg, Nathalie · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Cell bead based three-dimensional (3D) hepatic model toward high throughput drug-induced toxicity screening

Authors: Brandenberg, Nathalie

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/72909

Thesis Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

Hofer, Moritz · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

Authors: Hofer, Moritz

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/208043

Thesis Bioengineering human mini-intestines with in vivo-like complexity and function

Mitrofanova, Olga · 2023 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineering human mini-intestines with in vivo-like complexity and function

Authors: Mitrofanova, Olga

Year: 2023

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/199969

Thesis In vitro micro-physiological models for translational immunology

Ramadan, Qasem; Gijs, Martin A. M. · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: In vitro micro-physiological models for translational immunology

Authors: Ramadan, Qasem; Gijs, Martin A. M.

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/114524

Thesis Screening out irrelevant cell-based models of disease

Horvath, Peter; Aulner, Nathalie; Bickle, Marc et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Screening out irrelevant cell-based models of disease

Authors: Horvath, Peter; Aulner, Nathalie; Bickle, Marc; Davies, Anthony M.; Del Nery, Elaine; Ebner, Daniel; Montoya, Maria C.; Ostling, Paivi; Pietiainen, Vilja; Price, Leo S.; Shorte, Spencer L.; Turcatti, Gerardo; Von Schantz, Carina; Carragher, Neil O.

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/133719

Thesis Bioengineered Tubular Biliary Organoids

Elci, Bilge Sen; Nikolaev, Mikhail; Rezakhani, Saba et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bioengineered Tubular Biliary Organoids

Authors: Elci, Bilge Sen; Nikolaev, Mikhail; Rezakhani, Saba; Lutolf, Matthias P

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/205046

Thesis A pure population of ectodermal cells derived from human embryonic stem cells

Aberdam, Edith; Barak, Efrat; Rouleau, Matthieu et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A pure population of ectodermal cells derived from human embryonic stem cells

Authors: Aberdam, Edith; Barak, Efrat; Rouleau, Matthieu; de LaForest, Stephanie; Berrih-Aknin, Sonia; Suter, David M.; Krause, Karl-Heinz; Amit, Michal; Itskovitz-Eldor, Joseph; Aberdam, Daniel

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/92282

Thesis Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans

Cornaglia, Matteo; Lehnert, Thomas; Gijs, Martin A. M. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans

Authors: Cornaglia, Matteo; Lehnert, Thomas; Gijs, Martin A. M.

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/142553

Thesis BIOENGINEERED HUMAN MICROPHYSIOLOGICAL SYSTEMS FOR HIGH-THROUGHPUT NEUROMUSCULAR AND CARDIAC FUNCTIONAL ANALYSIS

Kim, Byunggik · 2025 · Johns Hopkins University · DOI

Full title: BIOENGINEERED HUMAN MICROPHYSIOLOGICAL SYSTEMS FOR HIGH-THROUGHPUT NEUROMUSCULAR AND CARDIAC FUNCTIONAL ANALYSIS

Authors: Kim, Byunggik

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70713

Thesis Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Lawlor, KT; Vanslambrouck, JM; Higgins, JW et al. · 2021 · University of Melbourne · DOI

Full title: Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Authors: Lawlor, KT; Vanslambrouck, JM; Higgins, JW; Chambon, A; Bishard, K; Arndt, D; Er, PX; Wilson, SB; Howden, SE; Tan, KS; Li, F; Hale, LJ; Shepherd, B; Pentoney, S; Presnell, SC; Chen, AE; Little, MH

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/278594

Thesis A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells

Hall, J; Daniszewski, M; Cheung, S et al. · 2023 · University of Melbourne · DOI

Full title: A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells

Authors: Hall, J; Daniszewski, M; Cheung, S; Shobhana, K; Kumar, H; Liang, HH; Beetham, H; Cho, E; Abbott, C; Hewitt, AW; Simpson, KJ; Guymer, RH; Paull, D; Pebay, A; Lidgerwood, GE

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/338691

Thesis Discovery of novel small-molecule inducers of heme oxygenase-1 that protect human ipsc-derived cardiomyocytes from oxidative stress

Kirby, RJ; Divlianska, DB; Whig, K et al. · 2022 · University of Melbourne · DOI

Full title: Discovery of novel small-molecule inducers of heme oxygenase-1 that protect human ipsc-derived cardiomyocytes from oxidative stress

Authors: Kirby, RJ; Divlianska, DB; Whig, K; Bryan, N; Morfa, CJ; Koo, A; Nguyen, KH; Maloney, P; Peddibhotla, S; Sessions, EH; Hershberger, PM; Smith, LH; Malany, S

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/304264

Thesis Translational Pharmacology and Clinical Trials

Li, M; Stewart, AG · 2023 · University of Melbourne · DOI

Full title: Translational Pharmacology and Clinical Trials

Authors: Li, M; Stewart, AG

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/332350

Thesis Anti-fibrotic strategies and pulmonary fibrosis

Gunatilaka, A; Zhang, S; Tan, WSD et al. · 2023 · University of Melbourne · DOI

Full title: Anti-fibrotic strategies and pulmonary fibrosis

Authors: Gunatilaka, A; Zhang, S; Tan, WSD; G. Stewart, A

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/332354

Thesis A village in a dish model system for population-scale hiPSC studies

Neavin, DR; Steinmann, AM; Farbehi, N et al. · 2023 · University of Melbourne · DOI

Full title: A village in a dish model system for population-scale hiPSC studies

Authors: Neavin, DR; Steinmann, AM; Farbehi, N; Chiu, HS; Daniszewski, MS; Arora, H; Bermudez, Y; Moutinho, C; Chan, CL; Bax, M; Tyebally, M; Gnanasambandapillai, V; Lam, CE; Nguyen, U; Hernández, D; Lidgerwood, GE; Graham, RM; Hewitt, AW; Pébay, A; Palpant, NJ; Powell, JE

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/338774

Thesis The development of improved and new in vitro assays for detecting the genotoxic and non-genotoxic carcinogenic potential of chemicals in the discovery phase of drug development

Westerink, W.M.A. · 2011 · Wageningen University & Research · DOI

Full title: The development of improved and new in vitro assays for detecting the genotoxic and non-genotoxic carcinogenic potential of chemicals in the discovery phase of drug development

Authors: Westerink, W.M.A.

Year: 2011

Venue: Wageningen University & Research

DOI: https://research.wur.nl/en/publications/the-development-of-improved-and-new-in-vitro-assays-for-detecting

Thesis The artificial gut : integrating in vitro models of the human digestive tract with mass spectrometry

Santbergen, Milou J.C. · 2020 · Wageningen University & Research · DOI

Full title: The artificial gut : integrating in vitro models of the human digestive tract with mass spectrometry

Authors: Santbergen, Milou J.C.

Year: 2020

Venue: Wageningen University & Research

DOI: https://research.wur.nl/en/publications/the-artificial-gut-integrating-in-vitro-models-of-the-human-diges

Thesis Building a human lung from pluripotent stem cells to model respiratory viral infections

Turner, DL; Amoozadeh, S; Baric, H et al. · 2024 · University of Melbourne · DOI

Full title: Building a human lung from pluripotent stem cells to model respiratory viral infections

Authors: Turner, DL; Amoozadeh, S; Baric, H; Stanley, E; Werder, RB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349879

Thesis A novel method for predicting human cardiotoxicity without animal testing

Shi, Miaoying · 2021 · Wageningen University & Research · DOI

Full title: A novel method for predicting human cardiotoxicity without animal testing

Authors: Shi, Miaoying

Year: 2021

Venue: Wageningen University & Research

DOI: https://research.wur.nl/en/publications/a-novel-method-for-predicting-human-cardiotoxicity-without-animal

Thesis An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

Willoughby, LF; Schlosser, T; Manning, SA et al. · 2014 · University of Melbourne · DOI

Full title: An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

Authors: Willoughby, LF; Schlosser, T; Manning, SA; Parisot, JP; Street, IP; Richardson, HE; Humbert, PO; Brumby, AM

Year: 2014

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/41096

Thesis Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats

Richert, Lysiane; Baze, Audrey; Parmentier, Celine et al. · 2016 · University of Liverpool · DOI

Full title: Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats

Authors: Richert, Lysiane; Baze, Audrey; Parmentier, Celine; Gerets, Helga HJ; Sison-Young, Rowena; Dorau, Martina; Lovatt, Cerys; Czich, Andreas; Goldring, Christopher; Park, B Kevin; Juhila, Satu; Foster, Alison J; Williams, Dominic P

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3004331/1/Revised%20-%20cytotoxicity%20evaluation.docx

Thesis Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Bell, Catherine C; Dankers, Anita CA; Lauschke, Volker M et al. · 2018 · University of Liverpool · DOI

Full title: Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Authors: Bell, Catherine C; Dankers, Anita CA; Lauschke, Volker M; Sison-Young, Rowena; Jenkins, Roz; Rowe, Cliff; Goldring, Chris E; Park, Kevin; Regan, Sophie L; Walker, Tracy; Schofield, Chris; Baze, Audrey; Foster, Alison J; Williams, Dominic P; van de Ven, Amy WM; Jacobs, Frank; van Houdt, Jos; Lahteenmaki, Tuula; Snoeys, Jan; Juhila, Satu; Richert, Lysiane; Ingelman-Sundberg, Magnus

Year: 2018

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3014674/1/Spheroid%20manuscript%2020171130-clean.docx

Thesis Test systems in Drug Discovery for hazard identification and risk assessment of human Drug-Induced Liver Injury.

Weaver, RJ; Betts, C; Blomme, EAG et al. · 2017 · University of Liverpool · DOI

Full title: Test systems in Drug Discovery for hazard identification and risk assessment of human Drug-Induced Liver Injury.

Authors: Weaver, RJ; Betts, C; Blomme, EAG; Gerets, HHJ; Gjervig Jensen, K; Hewitt, PG; Juhila, S; Labbe, G; Liguori, MJ; Mesens, N; Ogese, MO; Persson, M; Snoeys, J; Stevens, JL; Walker, T; Park, BK

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3007995/1/MS%20DILI%20Test%20Systems%20Manuscript%20EFPIA%20text%20tables%20%2003_06_17%20RW%20Clean.docx

Thesis Innovative Organotypic In Vitro Models for Safety Assessment: Aligning with regulatory requirements and understanding models of the heart, skin and liver as paradigms

Park, BK; Goldring, Christopher · 2018 · University of Liverpool · DOI

Full title: Innovative Organotypic In Vitro Models for Safety Assessment: Aligning with regulatory requirements and understanding models of the heart, skin and liver as paradigms

Authors: Park, BK; Goldring, Christopher

Year: 2018

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3015629/1/Innovative%20In%20Vitro%20Models%20for%20Safety%20Assessment%20V4.4.docx

Thesis The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Kamalian, Laleh; Douglas, Oisin; Jolly, Carol E et al. · 2018 · University of Liverpool · DOI

Full title: The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Authors: Kamalian, Laleh; Douglas, Oisin; Jolly, Carol E; Snoeys, Jan; Simic, Damir; Monshouwer, Mario; Williams, Dominic P; Park, B Kevin; Chadwick, Amy E

Year: 2018

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3025983/1/Resubmission_HepaRG_Final.docx

Thesis Stem Cell-Derived Models to Improve Mechanistic Understanding and Prediction of Human Drug-Induced Liver Injury

Goldring, Christopher; Antoine, Daniel J; Bonner, Frank et al. · 2017 · University of Liverpool · DOI

Full title: Stem Cell-Derived Models to Improve Mechanistic Understanding and Prediction of Human Drug-Induced Liver Injury

Authors: Goldring, Christopher; Antoine, Daniel J; Bonner, Frank; Crozier, Jonathan; Denning, Chris; Fontana, Robert J; Hanley, Neil A; Hay, David C; Ingelman-Sundberg, Magnus; Juhila, Satu; Kitteringham, Neil; Silva-Lima, Beatriz; Norris, Alan; Pridgeon, Chris; Ross, James A; Young, Rowena Sison; Tagle, Danilo; Tornesi, Belen; de Water, Bob van; Weaver, Richard J; Zhang, Fang; Park, B Kevin

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3015631/1/HEP-16-0938%20mark%20up-cg.docx

Thesis SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner

Moroni, Lorenzo; Barbaro, Fulvio; Caiment, Florian et al. · 2020 · University of Liverpool · DOI

Full title: SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner

Authors: Moroni, Lorenzo; Barbaro, Fulvio; Caiment, Florian; Coleman, Orla; Costagliola, Sabine; Di Conza, Giusy; Elviri, Lisa; Giselbrecht, Stefan; Krause, Christian; Mota, Carlos; Nazzari, Marta; Pennington, Stephen R; Ringwald, Annette; Sandri, Monica; Thomas, Simon; Waddington, James; Toni, Roberto

Year: 2020

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3129973

Thesis Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Foster, Alison J; Chouhan, Bhavik; Regan, Sophie L et al. · 2019 · University of Liverpool · DOI

Full title: Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Authors: Foster, Alison J; Chouhan, Bhavik; Regan, Sophie L; Rollison, Helen; Amberntsson, Sara; Andersson, Linda C; Srivastava, Abhishek; Darnell, Malin; Cairns, Jonathan; Lazic, Stanley E; Jang, Kyung-Jin; Petropolis, Debora B; Kodella, Konstantia; Rubins, Jonathan E; Williams, Dominic; Hamilton, Geraldine A; Ewart, Lorna; Morgan, Paul

Year: 2019

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3076470

Thesis Human hepatocytes: isolation, culture, and quality procedures.

Knobeloch, D; Ehnert, S; Schyschka, L et al. · 2012 · Technical University of Munich (TUM) · DOI

Full title: Human hepatocytes: isolation, culture, and quality procedures.

Authors: Knobeloch, D;Ehnert, S;Schyschka, L;Büchler, P;Schoenberg, M;Kleeff, J;Thasler, WE;Nüssler, NC;Godoy, P;Hengstler, J;Nüssler, AK

Year: 2012

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1181175

Thesis Pluripotent stem cell models of human heart disease.

Moretti, Alessandra; Laugwitz, Karl-Ludwig; Dorn, Tatjana et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Pluripotent stem cell models of human heart disease.

Authors: Moretti, Alessandra;Laugwitz, Karl-Ludwig;Dorn, Tatjana;Sinnecker, Daniel;Mummery, Christine

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1211120

Thesis Recapitulating long-QT syndrome using induced pluripotent stem cell technology.

Dirschinger, RJ; Goedel, A; Moretti, A et al. · 2012 · Technical University of Munich (TUM) · DOI

Full title: Recapitulating long-QT syndrome using induced pluripotent stem cell technology.

Authors: Dirschinger, RJ;Goedel, A;Moretti, A;Laugwitz, KL;Sinnecker, D

Year: 2012

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1181542

Thesis HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.

Lübberstedt, M; Müller-Vieira, U; Mayer, M et al. · 2011 · Technical University of Munich (TUM) · DOI

Full title: HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.

Authors: Lübberstedt, M;Müller-Vieira, U;Mayer, M;Biemel, KM;Knöspel, F;Knobeloch, D;Nüssler, AK;Gerlach, JC;Zeilinger, K

Year: 2011

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590036

Thesis Exploring in vitro modeling in hepatocarcinogenesis research: morphological and molecular features and similarities to the corresponding human disease

Valente, Leticia Cardoso [UNESP]; Bacil, Gabriel Prata [UNESP]; Riechelmann-Casarin, Luana [UNESP] et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Exploring in vitro modeling in hepatocarcinogenesis research: morphological and molecular features and similarities to the corresponding human disease

Authors: Valente, Leticia Cardoso [UNESP]; Bacil, Gabriel Prata [UNESP]; Riechelmann-Casarin, Luana [UNESP]; Barbosa, Giullia Cavichiolli [UNESP]; Barbisan, Luís Fernando [UNESP]; Romualdo, Guilherme Ribeiro [UNESP]

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1016/j.lfs.2024.122781

Thesis Synthetic PEG-Maleimide Hydrogel For In Vitro Culture of Primary Human Intestinal Enteroids

Hewes, Jacob D. · 2025 · Georgia Institute of Technology · DOI

Full title: Synthetic PEG-Maleimide Hydrogel For In Vitro Culture of Primary Human Intestinal Enteroids

Authors: Hewes, Jacob D.

Year: 2025

Venue: Georgia Institute of Technology

DOI: https://hdl.handle.net/1853/78618

Thesis Organoids

Zhao, Zixuan; Chen, Xinyi; Dowbaj, Anna M. et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Organoids

Authors: Zhao, Zixuan; Chen, Xinyi; Dowbaj, Anna M.; Sljukic, Aleksandra; Bratlie, Kaitlin; Lin, Luda; Fong, Eliza Li Shan; Balachander, Gowri Manohari; Chen, Zhaowei; Soragni, Alice; Huch, Meritxell; Zeng, Yi Arial; Wang, Qun; Yu, Hanry

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145617

Thesis Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs

Jin, Yunjung; Bu, Guojun; Zhao, Na · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs

Authors: Jin, Yunjung; Bu, Guojun; Zhao, Na

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-145427

Thesis A High-Throughput and Logarithm-Serial-Dilution Microfluidic Chip for Combinational Drug Screening on Tumor Organoids

Yan, Xingyang; Tan, Deng; Yu, Lei et al. · 2024 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: A High-Throughput and Logarithm-Serial-Dilution Microfluidic Chip for Combinational Drug Screening on Tumor Organoids

Authors: Yan, Xingyang; Tan, Deng; Yu, Lei; Li, Danyu; Huang, Wei; Huang, Weiren; Wu, Hongkai

Year: 2024

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-147029

Thesis Droplet-engineered organoids recapitulate parental tissue transcriptome with inter-organoid homogeneity and inter-tumor cell heterogeneity

Zhao, Haoran; Cheng, Yifan; Li, Jiawei et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Droplet-engineered organoids recapitulate parental tissue transcriptome with inter-organoid homogeneity and inter-tumor cell heterogeneity

Authors: Zhao, Haoran; Cheng, Yifan; Li, Jiawei; Zhou, Jiaqi; Yang, Haowei; Yu, Feng; Yu, Feihong; Khutsishvili, Davit; Wang, Zitian; Jiang, Shengwei; Tan, Kaixin; Kuang, Yi; Xing, Xinhui; Ma, Shaohua

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-118659

Thesis Modeling neurodegenerative microenvironment using cortical organoids derived from human stem cells

Yan, Yuanwei; Song, Liqing; Bejoy, Julie et al. · 2018 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Modeling neurodegenerative microenvironment using cortical organoids derived from human stem cells

Authors: Yan, Yuanwei; Song, Liqing; Bejoy, Julie; Zhao, Jing; Kanekiyo, Takahisa; Bu, Guojun; Zhou, Yi; Li, Yan

Year: 2018

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-130455

Thesis A Gut-on-a-chip Model for Testing the Anti-inflammatory Effects of Active Compounds

Fois, Chiara Anna Maria · 2021 · University of Sydney · DOI

Full title: A Gut-on-a-chip Model for Testing the Anti-inflammatory Effects of Active Compounds

Authors: Fois, Chiara Anna Maria

Year: 2021

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/25967

Thesis Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research

Wang, Xiaocheng; He, Jiaxin; Zhang, Qiang et al. · 2025 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research

Authors: Wang, Xiaocheng; He, Jiaxin; Zhang, Qiang; He, Juan; Wang, Qingwen

Year: 2025

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-149793

Thesis Nanofiber Membrane Supported Lung-on-a-Chip Microdevice for Anti-Cancer Drug Testing

Yang, Xingyuan; Li, Kaiyan; Zhang, Xu et al. · 2018 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Nanofiber Membrane Supported Lung-on-a-Chip Microdevice for Anti-Cancer Drug Testing

Authors: Yang, Xingyuan; Li, Kaiyan; Zhang, Xu; Liu, Chang; Guo, Bingkun; Wen, Weijia; Gao, Xinghua

Year: 2018

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-89062

Thesis Advancing in-vitro blood-brain barrier models using lipid-based nanoparticles as a strategy for drug delivery

Varanasi, Ramya · 2020 · University of Sydney · DOI

Full title: Advancing in-vitro blood-brain barrier models using lipid-based nanoparticles as a strategy for drug delivery

Authors: Varanasi, Ramya

Year: 2020

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/25558

Thesis Selecting the right therapeutic target for kidney disease

Buvall, Lisa; Menzies, Robert I; Williams, Julie et al. · 2023 · Imperial College London · DOI

Full title: Selecting the right therapeutic target for kidney disease

Authors: Buvall, Lisa; Menzies, Robert I; Williams, Julie; Woollard, Kevin J; Kumar, Chanchal; Granqvist, Anna B; Fritsch, Maria; Feliers, Denis; Reznichenko, Anna; Gianni, Davide; Petrovski, Slave; Bendtsen, Claus; Bohlooly-Y, Mohammad; Haefliger, Carolina; Danielson, Regina Fritsche; Hansen, Pernille BL

Year: 2023

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000885440400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Wound-on-Chip: A New Device for Studying Inflammation Phase of Wound Healing and Drug Discovery

Biglari, Sahar · 2019 · University of Sydney · DOI

Full title: Wound-on-Chip: A New Device for Studying Inflammation Phase of Wound Healing and Drug Discovery

Authors: Biglari, Sahar

Year: 2019

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/20128

Thesis High throughput drug discovery towards novel therapeutics for snakebite dermonecrosis

Tuersley, Joseph · 2025 · Imperial College London · DOI

Full title: High throughput drug discovery towards novel therapeutics for snakebite dermonecrosis

Authors: Tuersley, Joseph

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/122998

Thesis An Organ-on-a-chip model of pulmonary arterial hypertension

Ainscough, Alexander James · 2024 · Imperial College London · DOI

Full title: An Organ-on-a-chip model of pulmonary arterial hypertension

Authors: Ainscough, Alexander James

Year: 2024

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/110639

Thesis Vascularized and perfusable human heart-on-a-chip model recapitulates aspects of 1 myocardial ischemia and enables analysis of nanomedicine delivery

Kim, Junyoung; Zhang, Xuening; Wang, Richard et al. · 2025 · Imperial College London · DOI

Full title: Vascularized and perfusable human heart-on-a-chip model recapitulates aspects of 1 myocardial ischemia and enables analysis of nanomedicine delivery

Authors: Kim, Junyoung; Zhang, Xuening; Wang, Richard; Najer, Adrian; Lau, Qiao You; Cammack, Ana; Kim, Jang Ah; Kang, Yoo Kyung; Xie, Ruoxiao; Kim, Hyemin; Xie, Kai; Lim, Hyeonji; Park, Tae-Eun; Joo, Jinmyoung; Stevens, Molly

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/121913

Thesis Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations

Langley, GR; Adcock, IM; Busquet, F et al. · 2017 · Imperial College London · DOI

Full title: Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations

Authors: Langley, GR; Adcock, IM; Busquet, F; Crofton, KM; Csernok, E; Giese, C; Heinonen, T; Herrmann, K; Hofmann-Apitius, M; Landesmann, B; Marshall, LJ; McIvor, E; Muotri, AR; Noor, F; Schutte, K; Seidle, T; van de Stolpe, A; Van Esch, H; Willett, C; Woszczek, G

Year: 2017

Venue: Imperial College London

DOI: http://www.ncbi.nlm.nih.gov/pubmed/27989722

Thesis A human PCLS model of lung injury and repair for discovery and pharmaceutical research

Bankole, Esther; Wong, Chun Wai; Kim, Sally et al. · 2025 · Imperial College London · DOI

Full title: A human PCLS model of lung injury and repair for discovery and pharmaceutical research

Authors: Bankole, Esther; Wong, Chun Wai; Kim, Sally; Hind, Matthew; Dean, Charlotte

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/121469

Thesis A bioengineered three-dimensional cell culture platform integrated with microfluidics to address antimicrobial resistance in tuberculosis

Bielecka, MK; Tezera, LB; Zmijan, R et al. · 2017 · Imperial College London · DOI

Full title: A bioengineered three-dimensional cell culture platform integrated with microfluidics to address antimicrobial resistance in tuberculosis

Authors: Bielecka, MK; Tezera, LB; Zmijan, R; Drobniewski, F; Zhang, X; Jayasinghe, S; Elkington, P

Year: 2017

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000395835000004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Development of high content imaging methods for cell death detection in human pluripotent stem cell-derived cardiomyocytes

Mioulane, Maxime; Foldes, Gabor; Ali, Nadire N et al. · 2018 · Imperial College London · DOI

Full title: Development of high content imaging methods for cell death detection in human pluripotent stem cell-derived cardiomyocytes

Authors: Mioulane, Maxime; Foldes, Gabor; Ali, Nadire N; Schneider, Michael D; Harding, Sian E

Year: 2018

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308955500004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.

Kuepfer, L; Clayton, O; Thiel, C et al. · 2017 · Imperial College London · DOI

Full title: A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.

Authors: Kuepfer, L; Clayton, O; Thiel, C; Cordes, H; Nudischer, R; Blank, LM; Baier, V; Heymans, S; Caiment, F; Roth, A; Fluri, DA; Kelm, JM; Castell, J; Selevsek, N; Schlapbach, R; Keun, H; Hynes, J; Sarkans, U; Gmuender, H; Herwig, R; Niederer, S; Schuchhardt, J; Segall, M; Kleinjans, J

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/53952

Thesis An ex vivo acid injury and repair (AIR) model using precision-cut lung slices to understand lung injury and repair

Kim, Sally; Mongey, Roisin; Griffiths, Mark et al. · 2021 · Imperial College London · DOI

Full title: An ex vivo acid injury and repair (AIR) model using precision-cut lung slices to understand lung injury and repair

Authors: Kim, Sally; Mongey, Roisin; Griffiths, Mark; Hind, Matthew; Dean, Charlotte

Year: 2021

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/85304

Thesis Application of human induced pluripotent stem cell technology for cardiovascular regenerative pharmacology.

Majid, Qasim A; Orsolits, Barbara; Pohjolainen, Lotta et al. · 2021 · Imperial College London · DOI

Full title: Application of human induced pluripotent stem cell technology for cardiovascular regenerative pharmacology.

Authors: Majid, Qasim A; Orsolits, Barbara; Pohjolainen, Lotta; Kovács, Zsófia; Földes, Gábor; Talman, Virpi

Year: 2021

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/33755910

Thesis Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

Karhu, S Tuuli; Välimäki, Mika J; Jumppanen, Mikael et al. · 2018 · Imperial College London · DOI

Full title: Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

Authors: Karhu, S Tuuli; Välimäki, Mika J; Jumppanen, Mikael; Kinnunen, Sini M; Pohjolainen, Lotta; Leigh, Robert S; Auno, Samuli; Földes, Gábor; Boije Af Gennäs, Gustav; Yli-Kauhaluoma, Jari; Ruskoaho, Heikki; Talman, Virpi

Year: 2018

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/29987409

Thesis Theranostics by testing CFTR modulators in patient-derived materials: The current status and a proposal for subjects with rare CFTR mutations

Amaral, Margarida D; de Boeck, Kris; on behalf of the ECFS Strategic Planning Task Force on ‘Speeding up access to new drugs for CF’ et al. · 2019 · Imperial College London · DOI

Full title: Theranostics by testing CFTR modulators in patient-derived materials: The current status and a proposal for subjects with rare CFTR mutations

Authors: Amaral, Margarida D; de Boeck, Kris; on behalf of the ECFS Strategic Planning Task Force on ‘Speeding up access to new drugs for CF’; Amaral, Margarida; Davies, Jane C; de Boeck, Kris; Drevinek, Pavel; Elborn, Stuart; Kerem, Eitan; Lee, Tim

Year: 2019

Venue: Imperial College London

DOI: https://www.sciencedirect.com/science/article/pii/S1569199319308148?via%3Dihub

Thesis A bioassay system of autologous human endothelial, smooth muscle cells and leucocytes for use in drug discovery, phenotyping and tissue engineering

Ahmetaj-Shala, Blerine; Kawai, Ryota; Marei, Isra et al. · 2019 · Imperial College London · DOI

Full title: A bioassay system of autologous human endothelial, smooth muscle cells and leucocytes for use in drug discovery, phenotyping and tissue engineering

Authors: Ahmetaj-Shala, Blerine; Kawai, Ryota; Marei, Isra; Nikolakopoulou, Zacharoula; Shih, Chih-Chin; Konain, Bhatti; Reed, Daniel M; Mongey, Róisín; Kirkby, Nicholas S; Mitchell, Jane A

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/74886

Thesis Generation and analysis of pluripotent stem cell-derived cardiomyocytes and endothelial cells for high content screening purposes

Berecz, Tünde; Husvéth-Tóth, Mária; Mioulane, Maxime et al. · 2019 · Imperial College London · DOI

Full title: Generation and analysis of pluripotent stem cell-derived cardiomyocytes and endothelial cells for high content screening purposes

Authors: Berecz, Tünde; Husvéth-Tóth, Mária; Mioulane, Maxime; Merkely, Béla; Apáti, Ágota; Földes, Gábor

Year: 2019

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/30941720

Thesis Developing a 3D model of the airways

Güney, Tankut Gökhan · 2021 · Imperial College London · DOI

Full title: Developing a 3D model of the airways

Authors: Güney, Tankut Gökhan

Year: 2021

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/87742

Thesis New modalities of 3D pluripotent stem cell-based assays in cardiovascular toxicity

Orsolits, Barbara; Kovács, Zsófia; Kriston-Vizi, János et al. · 2021 · Imperial College London · DOI

Full title: New modalities of 3D pluripotent stem cell-based assays in cardiovascular toxicity

Authors: Orsolits, Barbara; Kovács, Zsófia; Kriston-Vizi, János; Merkely, Béla; Földes, Gábor

Year: 2021

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/33854431

Thesis Rapid target validation in a Cas9-inducible hiPSC derived kidney model

Shamshirgaran, Yasaman; Jonebring, Anna; Svensson, Anna et al. · 2021 · Imperial College London · DOI

Full title: Rapid target validation in a Cas9-inducible hiPSC derived kidney model

Authors: Shamshirgaran, Yasaman; Jonebring, Anna; Svensson, Anna; Leefa, Isabelle; Bohlooly-Y, Mohammad; Firth, Mike; Woollard, Kevin J; Hofherr, Alexis; Rogers, Ian M; Hicks, Ryan

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000686663200047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart

van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen et al. · 2022 · Imperial College London · DOI

Full title: Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart

Authors: van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; Brundel, Bianca; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M; Dendorfer, Andreas; Duncker, Dirk J; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü, Can; Gyongyosi, Mariann; Guzik, Tomasz J; Hamdani, Nazha; Heymans, Stephane; Hilfiker, Andres; Hilfiker-Kleiner, Denise; Hoekstra, Alfons G; Hulot, Jean-Sébastien; Kuster, Diederik WD; van Laake, Linda W; Lecour, Sandrine; Leiner, Tim; Linke, Wolfgang A; Lumens, Joost; Lutgens, Esther; Madonna, Rosalinda; Maegdefessel, Lars; Mayr, Manuel; van der Meer, Peter; Passier, Robert; Perbellini, Filippo; Perrino, Cinzia; Pesce, Maurizio; Priori, Silvia; Remme, Carol Ann; Rosenhahn, Bodo; Schotten, Ulrich; Schulz, Rainer; Sipido, Karin; Sluijter, Joost PG; van Steenbeek, Frank; Steffens, Sabine; Terracciano, Cesare M; Tocchetti, Carlo Gabriele; Vlasman, Patricia; Yeung, Kak Khee; Zacchigna, Serena; Zwaagman, Dayenne; Thum, Thomas

Year: 2022

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/34999816

Thesis Development of angiogenesis assays using 3D-cell spheres

오수전 · 2017 · Seoul National University · DOI

Full title: Development of angiogenesis assays using 3D-cell spheres

Authors: 오수전

Year: 2017

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/135022

Thesis LifeTime and improving European healthcare through cell-based interceptive medicine

Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A et al. · 2022 · Imperial College London · DOI

Full title: LifeTime and improving European healthcare through cell-based interceptive medicine

Authors: Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A; Aerts, Stein; Amit, Ido; Bertero, Michela G; Bock, Christoph; Bredenoord, Annelien L; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; De Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernández, Xosé M; Figlerowicz, Marek; Gasser, Susan M; Hubner, Norbert; Kjems, Jørgen; Knoblich, Jürgen A; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean-Christophe; Marioni, John C; Marti-Renom, Marc A; Netea, Mihai G; Nickel, Dörthe; Nollmann, Marcelo; Novak, Halina R; Parkinson, Helen; Piccolo, Stefano; Pinheiro, Inês; Pombo, Ana; Popp, Christian; Reik, Wolf; Roman-Roman, Sergio; Rosenstiel, Philip; Schultze, Joachim L; Stegle, Oliver; Tanay, Amos; Testa, Giuseppe; Thanos, Dimitris; Theis, Fabian J; Torres-Padilla, Maria-Elena; Valencia, Alfonso; Vallot, Céline; van Oudenaarden, Alexander; Vidal, Marie; Voet, Thierry; LifeTime Community Working Groups

Year: 2022

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/32894860

Thesis Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes

Ryu, Bokyeong; Choi, Seong Woo; Lee, Seul-Gi et al. · 2023 · Seoul National University · DOI

Full title: Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes

Authors: Ryu, Bokyeong; Choi, Seong Woo; Lee, Seul-Gi; Jeong, Young-Hoon; Kim, Ukjin; Kim, Jin; Jung, Cho-Rok; Chung, Hyung-Min; Park, Jae-Hak; Kim, C-Yoon

Year: 2023

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/194744

Thesis Precise, high-throughput production of multicellular spheroids with a bespoke 3D bioprinter

Utama, Robert H; Atapattu, Lakmali; O’Mahony, Aidan P et al. · 2020 · UNSW Sydney · DOI

Full title: Precise, high-throughput production of multicellular spheroids with a bespoke 3D bioprinter

Authors: Utama, Robert H; Atapattu, Lakmali; O’Mahony, Aidan P; Fife, Christopher M; Baek, Jongho; Allard, Théophile; O’Mahony, Kieran J; Ribeiro, Julio; Gaus, Katharina ; https://orcid.org/0000-0002-8009-9658; Kavallaris, Maria ; https://orcid.org/0000-0003-2309-898X; Gooding, J Justin ; https://orcid.org/0000-0002-5398-0597

Year: 2020

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_83990

Thesis Culture of primary human meibomian gland cells from surgically excised eyelid tissue

Duong, HT; https://orcid.org/0000-0002-4049-854X; Phan, MAT et al. · 2023 · UNSW Sydney · DOI

Full title: Culture of primary human meibomian gland cells from surgically excised eyelid tissue

Authors: Duong, HT ; https://orcid.org/0000-0002-4049-854X; Phan, MAT ; https://orcid.org/0000-0002-1560-1816; Madigan, MC ; https://orcid.org/0000-0003-1053-6979; Stapleton, F ; https://orcid.org/0000-0002-7203-5443; Wilcsek, G; Willcox, M ; https://orcid.org/0000-0003-3842-7563; Golebiowski, B ; https://orcid.org/0000-0002-9348-6470

Year: 2023

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_84527

Thesis Organic Bioelectronics for In Vitro Systems.

Pitsalidis, Charalampos; Pappa, Anna-Maria; Boys, Alexander J et al. · 2021 · University of Cambridge · DOI

Full title: Organic Bioelectronics for In Vitro Systems.

Authors: Pitsalidis, Charalampos; Pappa, Anna-Maria; Boys, Alexander J; Fu, Ying; Moysidou, Chrysanthi-Maria; van Niekerk, Douglas; Saez, Janire; Savva, Achilleas; Iandolo, Donata; Owens, Róisín M

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/330725

Thesis Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Marx, Uwe; Andersson, Tommy B.; Bahinski, Anthony et al. · 2016 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Authors: Marx, Uwe; Andersson, Tommy B.; Bahinski, Anthony; Beilmann, Mario; Beken, Sonja; Cassee, Flemming R.; Cirit, Murat; Daneshian, Mardas; Fitzpatrick, Susan; Frey, Olivier; Gaertner, Claudia; Giese, Christoph; Griffith, Linda; Hartung, Thomas; Heringa, Minne B.; Hoeng, Julia; De Jong, Wim H.; Kojima, Hajime; Kuehnl, Jochen; Leist, Marcel; Luch, Andreas; Maschmeyer, Ilka; Sakharov, Dmitry; Sips, Adrienne J.A.M.; Steger-Hartmann, Thomas; Tagle, Danilo A.; Tonevitsky, Alexander; Tralau, Tewes; Tsyb, Sergej; Van De Stolpe, Anja; Vandebriel, Rob; Vulto, Paul; Wang, Jufeng; Wiest, Joachim; Rodenburg, Marleen; Roth, Adrian

Year: 2016

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/118971

Thesis A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

Kuepfer, Lars; Clayton, Olivia; Thiel, Christoph et al. · 2018 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

Authors: Kuepfer, Lars; Clayton, Olivia; Thiel, Christoph; Cordes, Henrik; Nudischer, Ramona; Blank, Lars M.; Baier, Vanessa; Heymans, Stephane; Caiment, Florian; Roth, Adrian; Fluri, David A.; Kelm, Jens M.; Castell, José; Selevsek, Nathalie; Schlapbach, Ralph; Keun, Hector; Hynes, James; Sarkans, Ugis; Gmuender, Hans; Herwig, Ralf; Niederer, Steven; Schuchhardt, Johannes; Segall, Matthew; Kleinjans, Jos

Year: 2018

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/192369

Thesis Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Kasendra, Magdalena; Tovaglieri, Alessio; Sontheimer-Phelps, Alexandra et al. · 2018 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Authors: Kasendra, Magdalena; Tovaglieri, Alessio; Sontheimer-Phelps, Alexandra; Jalili-Firoozinezhad, Sasan; Bein, Amir; Chalkiadaki, Angeliki; Scholl, William; Zhang, Cheng; Rickner, Hannah; Richmond, Camilla A.; Jiang, Li; Breault, David T.; Ingber, Donald E.

Year: 2018

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/244533

Thesis Integrated Microphysiological Systems: Transferable Organ Models and Recirculating Flow

Renggli, Kasper; id_orcid0000-0001-6865-4084; Rousset, Nassim et al. · 2019 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Integrated Microphysiological Systems: Transferable Organ Models and Recirculating Flow

Authors: Renggli, Kasper; id_orcid0000-0001-6865-4084; Rousset, Nassim; id_orcid0000-0001-6865-4084; Lohasz, Christian; Nguyen, Oanh T.P.; Hierlemann, Andreas; id_orcid0000-0001-6865-4084

Year: 2019

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/344033

Thesis Growth of Epithelial Organoids in a Defined Hydrogel

Broguiere, Nicolas; Isenmann, Luca; Hirt, Christian et al. · 2018 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Growth of Epithelial Organoids in a Defined Hydrogel

Authors: Broguiere, Nicolas; Isenmann, Luca; Hirt, Christian; Ringel, Till; Placzek, Silja; Cavalli, Emma; Ringnalda, Femke; Villiger, Lukas; Züllig, Richard; Lehmann, Roger; Rogler, Gerhard; Heim, Markus H.; Schüler, Julia; Zenobi-Wong, Marcy; id_orcid0000-0002-8522-9909; Schwank, Gerald

Year: 2018

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/302457

Thesis A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues

Lohasz, Christian; id_orcid0000-0001-8575-7392; Loretan, Jacqueline et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues

Authors: Lohasz, Christian; id_orcid0000-0001-8575-7392; Loretan, Jacqueline; Sterker, Dario; Görlach, Ekkehard; Renggli, Kasper; Argast, Paul; Frey, Olivier; Wiesmann, Marion; Wartmann, Markus; Rausch, Martin; Hierlemann, Andreas; id_orcid0000-0001-8575-7392

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/524088

Thesis Charting human development using a multi-endodermal organ atlas and organoid models

Yu, Qianhui; Kilik, Umut; Holloway, Emily M. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Charting human development using a multi-endodermal organ atlas and organoid models

Authors: Yu, Qianhui; Kilik, Umut; Holloway, Emily M.; Tsai, Yu-Hwai; Harmel, Christoph; Wu, Angeline; Wu, Joshua H.; Czerwinski, Michael; Childs, Charlie J.; He, Zhisong; id_orcid0000-0002-1502-4801; Capeling, Meghan M.; Glass, Ian A.; Glass, Ian A.; Higgins, Peter D.R.; Treutlein, Barbara; id_orcid0000-0002-1502-4801; Spence, Jason R.; Camp, J. Gray

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/491282

Thesis LifeTime and improving European healthcare through cell-based interceptive medicine

Rajewsky, Nikolaus; Almouzni, Genevieve; Gorski, Stanislaw A. et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: LifeTime and improving European healthcare through cell-based interceptive medicine

Authors: Rajewsky, Nikolaus; Almouzni, Genevieve; Gorski, Stanislaw A.; Aerts, Stein; Amit, Ido; Bertero, Michela G.; Bock, Christoph; Bredenoord, Annelien L.; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; de Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernández, Xosé M.; Figlerowicz, Marek; Gasser, Susanne M.; Hübner, Norbert; Kjems, Jørgen; Knoblich, Juergen A.; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean C.W.

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/452887

Thesis Advances in 3D Organoid Models for Stem Cell-Based Cardiac Regeneration

Martin, Marcy; Gähwiler, Eric K.N.; Generali, Melanie et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Advances in 3D Organoid Models for Stem Cell-Based Cardiac Regeneration

Authors: Martin, Marcy; Gähwiler, Eric K.N.; Generali, Melanie; Hoerstrup, Simon P.; Emmert, Maximilian Y.

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/606668

Thesis Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity

Nudischer, Ramona; Renggli, Kasper; id_orcid0000-0001-6865-4084 et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity

Authors: Nudischer, Ramona; Renggli, Kasper; id_orcid0000-0001-6865-4084; Hierlemann, Andreas; id_orcid0000-0001-6865-4084; Roth, Adrian B.; Bertinetti-Lapatki, Cristina

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/431106

Thesis In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip

Ortega, María A.; Rodríguez-Comas, Júlia; Yavas, Ozlem et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip

Authors: Ortega, María A.; Rodríguez-Comas, Júlia; Yavas, Ozlem; Velasco-Mallorquí, Ferran; Balaguer-Trias, Jordina; Parra, Victor; Novials, Anna; Servitja, Joan M.; Quidant, Romain; id_orcid0000-0001-8995-8976; Ramón-Azcón, Javier

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/481313

Thesis An open source based high content screening method for cell biology laboratories investigating cell spreading and adhesion

Schmandke, Andre; Schmandke, Antonio; Pietro, Maurianne A. et al. · 2013 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: An open source based high content screening method for cell biology laboratories investigating cell spreading and adhesion

Authors: Schmandke, Andre; Schmandke, Antonio; Pietro, Maurianne A.; Schwab, Martin E.

Year: 2013

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/73667

Thesis Deep visual proteomics reveals an in vivo-like phenotype of orthotopically transplanted human colon organoids

Post , Frederik; Hausmann, Annika; id_orcid0000-0001-8852-3444 et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Deep visual proteomics reveals an in vivo-like phenotype of orthotopically transplanted human colon organoids

Authors: Post , Frederik; Hausmann, Annika; id_orcid0000-0001-8852-3444; Kabatnik , Sonja; Steigerwald , Sophia; Brand , Alexandra; Clement , Ditte L.; Skov , Jonathan; Lõhmussaar , Kadi; Larsen , Hjalte L.; Maimets , Martti; Boye , Theresa L.; Jez , Gabriela; Sato , Toshiro; Steenholdt, Casper; Rosenberger , Florian; Mund , Andreas; Nielsen , Ole H.; Jensen , Kim B.; Mann , Matthias

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/786583

Thesis An integrated transcriptomic cell atlas of human endoderm-derived organoids

Xu, Quan; Halle, Lennard; Hediyeh-zadeh, Soroor et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: An integrated transcriptomic cell atlas of human endoderm-derived organoids

Authors: Xu, Quan; Halle, Lennard; Hediyeh-zadeh, Soroor; Kuijs, Merel; Riedweg, Rya; Kilik, Umut; Recaldin, Timothy; Yu, Qianhui; Rall, Isabell; Frum, Tristan; Adam, Lukas; Parikh, Shrey; Kfuri-Rubens, Raphael; Gander, Manuel; Klein, Dominik; Curion, Fabiola; He, Zhisong; id_orcid0000-0002-1502-4801; Fleck, Jonas Simon; Oost, Koen; Kahnwald, Maurice; Treutlein, Barbara; id_orcid0000-0002-1502-4801; et al.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/736071

Thesis The blood-brain barrier in a dish: a new multicellular in vitro model

Ogunshola, O; Al Ahmad, A · 2010 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: The blood-brain barrier in a dish: a new multicellular in vitro model

Authors: Ogunshola, O; Al Ahmad, A

Year: 2010

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/51430

Thesis Tubing-Free Microfluidic Microtissue Culture System Featuring Gradual, in vivo-Like Substance Exposure Profiles

Lohasz, Christian; Frey, Olivier; Bonanini, Flavio et al. · 2019 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Tubing-Free Microfluidic Microtissue Culture System Featuring Gradual, in vivo-Like Substance Exposure Profiles

Authors: Lohasz, Christian; Frey, Olivier; Bonanini, Flavio; Renggli, Kasper; id_orcid0000-0001-6865-4084; Hierlemann, Andreas; id_orcid0000-0001-6865-4084

Year: 2019

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/337139

Thesis Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy

Hirt, Christian; id_orcid0000-0003-4396-1496; Booij, Tijmen H. et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy

Authors: Hirt, Christian; id_orcid0000-0003-4396-1496; Booij, Tijmen H.; Grob, Linda; id_orcid0000-0003-4396-1496; Simmler, Patrik; Toussaint, Nora Christina; id_orcid0000-0003-4396-1496; Keller, David; Taube, Doreen; Ludwig, Vanessa; Goryachkin, Alexander; Pauli, Chantal; Lenggenhager, Daniela; Stekhoven, Daniel; id_orcid0000-0003-4396-1496; Stirnimann, Christian U.; Endhardt, Katharina; Ringnalda, Femke; Villiger, Lukas; Siebenhüner, Alexander; Karkampouna, Sofia; De Menna, Marta; Beshay, Janette; Schwank, Gerald; et al.

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/603044

Thesis Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open

Tredup, Claudia; Ackloo, Suzanne; Beck, Hartmut et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open

Authors: Tredup, Claudia; Ackloo, Suzanne; Beck, Hartmut; Brown, Peter J.; Bullock, Alex N.; Ciulli, Alessio; Dikic, Ivan; Edfeldt, Kristina; Edwards, Aled M.; Elkins, Jonathan M.; Farin, Henner F.; Fon, Edward A.; Gstaiger, Matthias; Günther, Judith; Gustavsson, Anna-Lena; Häberle, Sandra; Isigkeit, Laura; Huber, Kilian V.M.; Kotschy, Andras; Krämer, Oliver; et al.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/709890

Thesis A microfluidic platform for the co-culturing of microtissues with continuously recirculating suspension cells

Lohasz, Christian; id_orcid0000-0001-8575-7392; Häfeli, Tamara et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: A microfluidic platform for the co-culturing of microtissues with continuously recirculating suspension cells

Authors: Lohasz, Christian; id_orcid0000-0001-8575-7392; Häfeli, Tamara; id_orcid0000-0001-8575-7392; Hasanova, Dzhansu; Hölting , Lisa; Rudnik , Michal; Ligeon , Laure-Anne; Lützow , Svenja; Mehta , Avni; Kritzer , Bettina; Laternser , Sandra; Nazarian , Javad; Hierlemann, Andreas; id_orcid0000-0001-8575-7392; Frey , Olivier; Modena, Mario M.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/786119

Thesis Genome-scale CRISPR screening in human intestinal organoids identifies drivers of TGF-β resistance

Ringel, Till; Frey, Nina; Ringnalda, Femke et al. · 2020 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Genome-scale CRISPR screening in human intestinal organoids identifies drivers of TGF-β resistance

Year: 2020

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/170278

Thesis Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies

Bouwmeester, Manon C; Bernal, Paulina Nunez; Oosterhoff, Loes A et al. · 2021 · Utrecht University · DOI

Full title: Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies

Authors: Bouwmeester, Manon C; Bernal, Paulina Nunez; Oosterhoff, Loes A; van Wolferen, Monique; Lehmann, Vivian; Vermaas, Monique; Buchholz, Maj-Britt; Peiffer, Quentin; Malda, Jos; van der Laan, Luc J W; Kramer, Nynke I; Schneeberger, Kerstin; Levato, Riccardo; Spee, Bart

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/418931

Thesis Novel test strategies for in vitro seizure liability assessment

Tukker, Anke M; Westerink, Remco H S · 2021 · Utrecht University · DOI

Full title: Novel test strategies for in vitro seizure liability assessment

Authors: Tukker, Anke M; Westerink, Remco H S

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/417447

van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen et al. · 2022 · Utrecht University · DOI

Authors: van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; Brundel, Bianca; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M; Dendorfer, Andreas; Duncker, Dirk J; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü, Can; Gyongyosi, Mariann; Guzik, Tomasz J; Hamdani, Nazha; Heymans, Stephane; Hilfiker, Andres; Hilfiker-Kleiner, Denise; Hoekstra, Alfons G; Hulot, Jean-Sébastien; Kuster, Diederik W D; van Laake, Linda W; Lecour, Sandrine; Leiner, Tim; Linke, Wolfgang A; Lumens, Joost; Lutgens, Esther; Madonna, Rosalinda; Maegdefessel, Lars; Mayr, Manuel; van der Meer, Peter; Passier, Robert; Perbellini, Filippo; Perrino, Cinzia; Pesce, Maurizio; Priori, Silvia; Remme, Carol Ann; Rosenhahn, Bodo; Schotten, Ulrich; Sipido, Karin; Schulz, Rainer; Sluijter, Joost P G; van Steenbeek, Frank; Steffens, Sabine; Terracciano, Cesare M; Tocchetti, Carlo Gabriele; Vlasman, Patricia; Yeung, Kak Khee; Zacchigna, Serena; Zwaagman, Dayenne; Thum, Thomas

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/425613

Thesis Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E et al. · 2020 · Utrecht University · DOI

Full title: Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Authors: Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E; Copple, Ian M; Gerets, Helga H J; Goldring, Christopher E; Guillouzo, Andre; Hewitt, Philip G; Ingelman-Sundberg, Magnus; Jensen, Klaus Gjervig; Juhila, Satu; Klingmüller, Ursula; Labbe, Gilles; Liguori, Michael J; Lovatt, Cerys A; Morgan, Paul; Naisbitt, Dean J; Pieters, Raymond H H; Snoeys, Jan; van de Water, Bob; Williams, Dominic P; Park, B Kevin

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/432219

Thesis Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies

Bouwmeester, Manon C; Bernal, Paulina Nunez; Oosterhoff, Loes A et al. · 2021 · Utrecht University · DOI

Full title: Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/417606

Thesis Recommendations for robust and reproducible preclinical research in personalised medicine

PERMIT group; Fosse, Vibeke; Oldoni, Emanuela et al. · 2023 · Utrecht University · DOI

Full title: Recommendations for robust and reproducible preclinical research in personalised medicine

Authors: PERMIT group; Fosse, Vibeke; Oldoni, Emanuela; Bietrix, Florence; Budillon, Alfredo; Daskalopoulos, Evangelos P; Fratelli, Maddalena; Gerlach, Björn; Groenen, Peter M A; Hölter, Sabine M; Menon, Julia M L; Mobasheri, Ali; Osborne, Nikki; Ritskes-Hoitinga, Merel; Ryll, Bettina; Schmitt, Elmar; Ussi, Anton; Andreu, Antonio L; McCormack, Emmet

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426279

Thesis Novel test strategies for in vitro seizure liability assessment

Tukker, Anke M; Westerink, Remco H S · 2021 · Utrecht University · DOI

Full title: Novel test strategies for in vitro seizure liability assessment

Authors: Tukker, Anke M; Westerink, Remco H S

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/418771

Thesis The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development

Keuper-Navis, Marit; Walles, Markus; Poller, Birk et al. · 2023 · Utrecht University · DOI

Full title: The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development

Authors: Keuper-Navis, Marit; Walles, Markus; Poller, Birk; Myszczyszyn, Adam; van der Made, Thomas K; Donkers, Joanne; Amirabadi, Hossein Eslami; Wilmer, Martijn J; Aan, Saskia; Spee, Bart; Masereeuw, Rosalinde; van de Steeg, Evita

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/430857

Thesis Navigating Vascular Complexity: Insights From hiPSC-derived vascular cells to Advanced 3D Models

Meijer, Elana Marianne · 2024 · Utrecht University · DOI

Full title: Navigating Vascular Complexity: Insights From hiPSC-derived vascular cells to Advanced 3D Models

Authors: Meijer, Elana Marianne

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/437372

Thesis A novel KCNJ16 kidney organoid model recapitulates the disease phenotype and shows restoration of lipid accumulation upon treatment with statins

Garvi, Elena Sendino; Slobbe, Gijs van der; Zaal, Esther A et al. · 2023 · Utrecht University · DOI

Full title: A novel KCNJ16 kidney organoid model recapitulates the disease phenotype and shows restoration of lipid accumulation upon treatment with statins

Authors: Garvi, Elena Sendino; Slobbe, Gijs van der; Zaal, Esther A; Baaij, Jeroen H.F. de; Hoenderop, Joost; Masereeuw, Roos; Janssen, Manoe J.; Genderen, Anne Metje van

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/436049

Thesis LifeTime and improving European healthcare through cell-based interceptive medicine

Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A. et al. · 2020 · Utrecht University · DOI

Full title: LifeTime and improving European healthcare through cell-based interceptive medicine

Authors: Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A.; Aerts, Stein; Amit, Ido; Bertero, Michela G.; Bock, Christoph; Bredenoord, Annelien L.; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; De Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernández, Xosé M.; Figlerowicz, Marek; Gasser, Susan M.; Hubner, Norbert; Kjems, Jørgen; Knoblich, Jürgen A.; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean Christophe; Marioni, John; Marti-Renom, Marc A.; Netea, Mihai G.; Nickel, Dörthe; Nollmann, Marcelo; Novak, Halina R.; Parkinson, Helen; Piccolo, Stefano; Pinheiro, Inês; Pombo, Ana; Popp, Christian; Reik, Wolf; Roman-Roman, Sergio; Rosenstiel, Philip; Schultze, Joachim L.; Stegle, Oliver; Tanay, Amos; Testa, Giuseppe; Thanos, Dimitris; Theis, Fabian J.; Torres-Padilla, Maria Elena; van Oudenaarden, Alexander; Bruining, Hilgo; Jongsma, Karin R.; Pasterkamp, R. Jeroen; van Oudenaarden, Alexander; LifeTime Community

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440502

Thesis Airway organoids as models of human disease

van der Vaart, J.; Clevers, H. · 2021 · Utrecht University · DOI

Full title: Airway organoids as models of human disease

Authors: van der Vaart, J.; Clevers, H.

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439824

Thesis Establishment of patient-derived cancer organoids for drug-screening applications

Driehuis, Else; Kretzschmar, Kai; Clevers, Hans · 2020 · Utrecht University · DOI

Full title: Establishment of patient-derived cancer organoids for drug-screening applications

Authors: Driehuis, Else; Kretzschmar, Kai; Clevers, Hans

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440882

Thesis Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease

Pasteuning-Vuhman, Svetlana; de Jongh, Rianne; Timmers, Annabel et al. · 2021 · Utrecht University · DOI

Full title: Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease

Authors: Pasteuning-Vuhman, Svetlana; de Jongh, Rianne; Timmers, Annabel; Pasterkamp, R. Jeroen

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440977

Thesis Promises and challenges of organoid-guided precision medicine

Bose, Shree; Clevers, Hans; Shen, Xiling · 2021 · Utrecht University · DOI

Full title: Promises and challenges of organoid-guided precision medicine

Authors: Bose, Shree; Clevers, Hans; Shen, Xiling

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445585

Thesis Bioprinting of Human Liver-Derived Epithelial Organoids for Toxicity Studies

Bouwmeester, Manon C.; Bernal, Paulina N.; Oosterhoff, Loes A. et al. · 2021 · Utrecht University · DOI

Full title: Bioprinting of Human Liver-Derived Epithelial Organoids for Toxicity Studies

Authors: Bouwmeester, Manon C.; Bernal, Paulina N.; Oosterhoff, Loes A.; van Wolferen, Monique E.; Lehmann, Vivian; Vermaas, Monique; Buchholz, Maj Britt; Peiffer, Quentin C.; Malda, Jos; van der Laan, Luc J.W.; Kramer, Nynke I.; Schneeberger, Kerstin; Levato, Riccardo; Spee, Bart

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/444277

Thesis Rapid tissue prototyping with micro-organospheres

Wang, Zhaohui; Boretto, Matteo; Millen, Rosemary et al. · 2022 · Utrecht University · DOI

Full title: Rapid tissue prototyping with micro-organospheres

Authors: Wang, Zhaohui; Boretto, Matteo; Millen, Rosemary; Natesh, Naveen; Reckzeh, Elena S.; Hsu, Carolyn; Negrete, Marcos; Yao, Haipei; Quayle, William; Heaton, Brook E.; Harding, Alfred T.; Bose, Shree; Driehuis, Else; Beumer, Joep; Rivera, Grecia O.; van Ineveld, Ravian L.; Gex, Donald; DeVilla, Jessica; Wang, Daisong; Puschhof, Jens; Geurts, Maarten H.; Yeung, Athena; Hamele, Cait; Smith, Amber; Bankaitis, Eric; Xiang, Kun; Ding, Shengli; Nelson, Daniel; Delubac, Daniel; Rios, Anne; Abi-Hachem, Ralph; Jang, David; Goldstein, Bradley J.; Glass, Carolyn; Heaton, Nicholas S.; Hsu, David; Clevers, Hans; Shen, Xiling

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447775

Thesis Mogelijke toepassingen van organoïden in de geneeskunde

Mijnders, Marjolein; Fuchs, Sabine A; Nieuwenhuis, Edward E S · 2022 · Utrecht University · DOI

Full title: Mogelijke toepassingen van organoïden in de geneeskunde

Authors: Mijnders, Marjolein; Fuchs, Sabine A; Nieuwenhuis, Edward E S

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445928

Thesis Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids

Chen, Kevin G.; Zhong, Pingyu; Zheng, Wei et al. · 2019 · Utrecht University · DOI

Full title: Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids

Authors: Chen, Kevin G.; Zhong, Pingyu; Zheng, Wei; Beekman, Jeffrey M.

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/392052

Thesis Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

Jordan, Robert; Ford-Scheimer, Stephanie L.; Alarcon, Rodolfo M. et al. · 2023 · Utrecht University · DOI

Full title: Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

Authors: Jordan, Robert; Ford-Scheimer, Stephanie L.; Alarcon, Rodolfo M.; Atala, Anthony; Borenstein, Jeffrey T.; Brimacombe, Kyle R.; Cherry, Sara; Clevers, Hans; Davis, Mindy I.; Funnell, Simon G.P.; Gehrke, Lee; Griffith, Linda G.; Grossman, Abigail C.; Hartung, Thomas; Ingber, Donald E.; Kleinstreuer, Nicole C.; Kuo, Calvin J.; Lee, Emily M.; Mummery, Christine L.; Pickett, Thames E.; Ramani, Sasirekha; Rosado-Olivieri, Edwin A.; Struble, Evi B.; Wan, Zhengpeng; Williams, Mark S.; Hall, Matthew D.; Ferrer, Marc; Markossian, Sarine

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451178

Thesis FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

de Poel, E.; Spelier, S.; Hagemeijer, M. C. et al. · 2023 · Utrecht University · DOI

Full title: FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Authors: de Poel, E.; Spelier, S.; Hagemeijer, M. C.; van Mourik, P.; Suen, S. W.F.; Vonk, A. M.; Brunsveld, J. E.; Ithakisiou, G. N.; Kruisselbrink, E.; Oppelaar, H.; Berkers, G.; de Winter de Groot, K. M.; Heida-Michel, S.; Jans, S. R.; van Panhuis, H.; Bakker, M.; van der Meer, R.; Roukema, J.; Dompeling, E.; Weersink, E. J.M.; Koppelman, G. H.; Blaazer, A. R.; Muijlwijk-Koezen, J. E.; van der Ent, C. K.; Beekman, J. M.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/449138

Thesis Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity

Saglam-Metiner, Pelin; Yildirim, Ender; Dincer, Can et al. · 2024 · Utrecht University · DOI

Full title: Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity

Authors: Saglam-Metiner, Pelin; Yildirim, Ender; Dincer, Can; Basak, Onur; Yesil-Celiktas, Ozlem

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451196

Thesis Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology

Ji, Shuyi; Feng, Li; Fu, Zile et al. · 2023 · Utrecht University · DOI

Full title: Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology

Authors: Ji, Shuyi; Feng, Li; Fu, Zile; Wu, Gaohua; Wu, Yingcheng; Lin, Youpei; Lu, Dayun; Song, Yuanli; Cui, Peng; Yang, Zijian; Sang, Chen; Song, Guohe; Cai, Shangli; Li, Yuanchuang; Lin, Hanqing; Zhang, Shu; Wang, Xiaoying; Qiu, Shuangjian; Zhang, Xiaoming; Hua, Guoqiang; Li, Junqiang; Zhou, Jian; Dai, Zhi; Wang, Xiangdong; Ding, Li; Wang, Pei; Gao, Daming; Zhang, Bing; Rodriguez, Henry; Fan, Jia; Clevers, Hans; Zhou, Hu; Sun, Yidi; Gao, Qiang

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451190

Thesis Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids

Maas, Renee G C; Beekink, Tess; Chirico, Nino et al. · 2023 · Utrecht University · DOI

Full title: Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids

Authors: Maas, Renee G C; Beekink, Tess; Chirico, Nino; Snijders Blok, Christian J B; Dokter, Inge; Sampaio-Pinto, Vasco; van Mil, Alain; Doevendans, Pieter A; Buikema, Jan W; Sluijter, Joost P G; Stillitano, Francesca

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/449015

Thesis Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Bouwmeester, Manon C.; Tao, Yu; Proença, Susana et al. · 2023 · Utrecht University · DOI

Full title: Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Authors: Bouwmeester, Manon C.; Tao, Yu; Proença, Susana; van Steenbeek, Frank G.; Samsom, Roos Anne; Nijmeijer, Sandra M.; Sinnige, Theo; van der Laan, Luc J.W.; Legler, Juliette; Schneeberger, Kerstin; Kramer, Nynke I.; Spee, Bart

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/456016

Thesis Standardizing designed and emergent quantitative features in microphysiological systems

Nahon, Dennis M.; Moerkens, Renée; Aydogmus, Hande et al. · 2024 · Utrecht University · DOI

Full title: Standardizing designed and emergent quantitative features in microphysiological systems

Authors: Nahon, Dennis M.; Moerkens, Renée; Aydogmus, Hande; Lendemeijer, Bas; Martínez-Silgado, Adriana; Stein, Jeroen M.; Dostanić, Milica; Frimat, Jean Philippe; Gontan, Cristina; de Graaf, Mees N.S.; Hu, Michel; Kasi, Dhanesh G.; Koch, Lena S.; Le, Kieu T.T.; Lim, Sangho; Middelkamp, Heleen H.T.; Mooiweer, Joram; Motreuil-Ragot, Paul; Niggl, Eva; Pleguezuelos-Manzano, Cayetano; Puschhof, Jens; Revyn, Nele; Rivera-Arbelaez, José M.; Slager, Jelle; Windt, Laura M.; Zakharova, Mariia; van Meer, Berend J.; Orlova, Valeria V.; de Vrij, Femke M.S.; Withoff, Sebo; Mastrangeli, Massimo; van der Meer, Andries D.; Mummery, Christine L.

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/456102

Thesis INNOVATIVE IN VITRO PLATFORMS FOR INVESTIGATING THERAPEUTIC EFFECTS AND BIO-DISTRIBUTION OF EXTRACELLULAR VESICLES: Towards Animal-Free Kidney Disease Modelling

Nguyen, Vy · 2024 · Utrecht University · DOI

Full title: INNOVATIVE IN VITRO PLATFORMS FOR INVESTIGATING THERAPEUTIC EFFECTS AND BIO-DISTRIBUTION OF EXTRACELLULAR VESICLES: Towards Animal-Free Kidney Disease Modelling

Authors: Nguyen, Vy

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/456152

Thesis Kidney-based in vitro models for drug-induced toxicity testing

Faria, João; Ahmed, Sabbir; Gerritsen, Karin G.F. et al. · 2019 · Utrecht University · DOI

Full title: Kidney-based in vitro models for drug-induced toxicity testing

Authors: Faria, João; Ahmed, Sabbir; Gerritsen, Karin G.F.; Mihaila, Silvia M.; Masereeuw, Rosalinde

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/457613

Thesis Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

Stokes, Cynthia L; Tsamandouras, Nikolaos; Chen, Wen Li et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

Authors: Stokes, Cynthia L; Tsamandouras, Nikolaos; Chen, Wen Li; Edington, Collin D; Griffith, Linda G; Cirit, Murat

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/111057

Thesis Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

Stokes, Cynthia L; Tsamandouras, Nikolaos; Chen, Wen Li et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

Authors: Stokes, Cynthia L; Tsamandouras, Nikolaos; Chen, Wen Li; Edington, Collin D; Griffith, Linda G; Cirit, Murat

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/111036

Thesis Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Cirit, Murat · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Authors: Cirit, Murat

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/117681

Thesis A Novel Human Multi-Tissue System For Preclinical Drug Evaluation And Recapitulation Of Metastasis

Chramiec, Alan · 2022 · Columbia University · DOI

Full title: A Novel Human Multi-Tissue System For Preclinical Drug Evaluation And Recapitulation Of Metastasis

Authors: Chramiec, Alan

Year: 2022

Venue: Columbia University

DOI: https://doi.org/10.7916/mhn6-bm25

Thesis Human epidermal growth factor release from hyaluronic acid-based platforms towards in vitro expansion of salivary gland cells

Van, Toan Phan · 2022 · Chulalongkorn University · DOI

Full title: Human epidermal growth factor release from hyaluronic acid-based platforms towards in vitro expansion of salivary gland cells

Authors: Van, Toan Phan

Year: 2022

Venue: Chulalongkorn University

DOI: https://digital.car.chula.ac.th/chulaetd/12052

Thesis Modelling non-alcoholic fatty liver disease using patient derived liver stem cells and hepatic organoids

Lim, Yee Siang · 2020 · Nanyang Technological University (NTU) · DOI

Full title: Modelling non-alcoholic fatty liver disease using patient derived liver stem cells and hepatic organoids

Authors: Lim, Yee Siang

Year: 2020

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/139651

Thesis 3D KIDNEY ORGANOIDS AS A PLATFORM FOR INVESTIGATING MONOGENIC DISEASES AND GENE THERAPY APPROACHES

TESTA, MARIALUISA · 2025 · Università degli Studi di Milano (AIR) · DOI

Full title: 3D KIDNEY ORGANOIDS AS A PLATFORM FOR INVESTIGATING MONOGENIC DISEASES AND GENE THERAPY APPROACHES

Authors: TESTA, MARIALUISA

Year: 2025

Venue: Università degli Studi di Milano (AIR)

DOI: https://hdl.handle.net/2434/1203835

Thesis Human Liver Organoids Culture as a Personalised Approach in Assessing HBV Infection and Cellular Responses

Lim, Chuan Kok · 2021 · University of Adelaide · DOI

Full title: Human Liver Organoids Culture as a Personalised Approach in Assessing HBV Infection and Cellular Responses

Authors: Lim, Chuan Kok

Year: 2021

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/134568

Thesis Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

Nantasanti, Sathidpak; Spee, Bart; Kruitwagen, Hedwig S et al. · 2015 · Utrecht University · DOI

Full title: Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/333214

Thesis Tubuloids derived from human adult kidney and urine for personalized disease modeling

Schutgens, Frans; Rookmaaker, Maarten B; Margaritis, Thanasis et al. · 2019 · Utrecht University · DOI

Full title: Tubuloids derived from human adult kidney and urine for personalized disease modeling

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/379448

Thesis Canine Pituitary Organoids as 3D In Vitro Model for Cushing Disease

Sanders, Karin; Ringnalda, Femke C A; van de Wetering, Marc L et al. · 2021 · Utrecht University · DOI

Full title: Canine Pituitary Organoids as 3D In Vitro Model for Cushing Disease

Authors: Sanders, Karin; Ringnalda, Femke C A; van de Wetering, Marc L; Kooistra, Hans S; Meij, Björn P; Clevers, Hans; Galac, Sara

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/413998

Thesis A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

Nguyen, Vivian V.T.; Ye, Shicheng; Gkouzioti, Vasiliki et al. · 2022 · Utrecht University · DOI

Full title: A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

Authors: Nguyen, Vivian V.T.; Ye, Shicheng; Gkouzioti, Vasiliki; van Wolferen, Monique E.; Yengej, Fjodor Yousef; Melkert, Dennis; Siti, Sofia; de Jong, Bart; Besseling, Paul J.; Spee, Bart; van der Laan, Luc J.W.; Horland, Reyk; Verhaar, Marianne C.; van Balkom, Bas W.M.

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447651

Thesis Application of a human primary epithelial-fibroblast co-culture system to study fibrosis

Richardson, Jaineeta · 2017 · University of Nottingham · DOI

Full title: Application of a human primary epithelial-fibroblast co-culture system to study fibrosis

Authors: Richardson, Jaineeta

Year: 2017

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/46427/1/PhD%20Thesis%20Jaineeta%20Richardson.pdf

Thesis Pharmacological and toxicological characterisation of GATA4- and protein kinase C-targeted compounds in cardiac cell models

Karhu, Tuuli · 2021 · University of Helsinki (HELDA) · DOI

Full title: Pharmacological and toxicological characterisation of GATA4- and protein kinase C-targeted compounds in cardiac cell models

Authors: Karhu, Tuuli

Year: 2021

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/329583

Thesis A competition-based assay for the screening of species-specific antibiotics

Granieri, L.; Miller, O. J.; Griffiths, A. D. et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A competition-based assay for the screening of species-specific antibiotics

Authors: Granieri, L.; Miller, O. J.; Griffiths, A. D.; Merten, Christoph

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/166544

Thesis A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.

Sison-Young, RL; Lauschke, VM; Johann, E et al. · 2017 · University of Liverpool · DOI

Full title: A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3004313/1/Sison-Young%20Arch%20Toxicol%202016.pdf

Thesis Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies

Altmaier, Saskia; Meiser, Ina; Lemesre, Emilie et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/25d17948-a3d4-4d26-a51d-f92cc7bc8f6f

Thesis Novel approaches to 3D cancer heterospheroid culture and assay development for immunotherapy screening

Madsen, Natasha Helleberg; Nielsen, Boye Schnack; Skandorff, Isabella et al. · 2025 · Technical University of Denmark (DTU) · DOI

Full title: Novel approaches to 3D cancer heterospheroid culture and assay development for immunotherapy screening

Year: 2025

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/37b0424d-9118-4303-a180-a90d4c4e84e6

Thesis Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture

Vivas, Aisen; IJspeert, Camilo; Pan, Jesper Yue et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/bb82a97f-4e87-4b9e-b674-5f8f3e2bde2e

Thesis A Microscale High-Throughput Phenotypic Assay to Evaluate ECM Remodeling in Pulmonary Fibrosis

Robinson, Stephen Timothy · 2021 · Georgia Institute of Technology · DOI

Full title: A Microscale High-Throughput Phenotypic Assay to Evaluate ECM Remodeling in Pulmonary Fibrosis

Authors: Robinson, Stephen Timothy

Year: 2021

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/65002

Thesis Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing

Tom, O'Brien; Ida, Barlow; Luigi, Feriani et al. · 2023 · Imperial College London · DOI

Full title: Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing

Authors: Tom, O'Brien; Ida, Barlow; Luigi, Feriani; Brown, Andre

Year: 2023

Venue: Imperial College London

DOI: https://elifesciences.org/reviewed-preprints/92491

Thesis Myocardial slices come to age: An intermediate complexity in vitro cardiac model for translational research

Pitoulis, Fotios; Watson, Samuel; Perbellini, Filippo et al. · 2019 · Imperial College London · DOI

Full title: Myocardial slices come to age: An intermediate complexity in vitro cardiac model for translational research

Authors: Pitoulis, Fotios; Watson, Samuel; Perbellini, Filippo; Terracciano, Cesare

Year: 2019

Venue: Imperial College London

DOI: https://academic.oup.com/cardiovascres/article/116/7/1275/5685810

Thesis Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells

Ryu, Bokyeong; Son, Mi-Young; Jung, Kwang Bo et al. · 2023 · Seoul National University · DOI

Full title: Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells

Authors: Ryu, Bokyeong; Son, Mi-Young; Jung, Kwang Bo; Kim, Ukjin; Kim, Jin; Kwon, Ohman; Son, Ye Seul; Jung, Cho-Rok; Park, Jae-Hak; Kim, C-Yoon

Year: 2023

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/194734

Thesis Monitoring and manipulating cellular crosstalk during kidney fibrosis inside a 3D in vitro co-culture

Nugraha, Bramasta; Mohr, Manuel A; Ponti, Aaron et al. · 2020 · Imperial College London · DOI

Full title: Monitoring and manipulating cellular crosstalk during kidney fibrosis inside a 3D in vitro co-culture

Authors: Nugraha, Bramasta; Mohr, Manuel A; Ponti, Aaron; Emmert, Maximilian Y; Weibel, Franziska; Hoerstrup, Simon P; Moll, Solange; Certa, Ulrich; Prunotto, Marco; Pantazis, Periklis

Year: 2020

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000414407900020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Monitoring and manipulating cellular crosstalk during kidney fibrosis inside a 3D in vitro co-culture

Nugraha, Bramasta; Moh, Manuel A.; Ponti, Aaron et al. · 2017 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Monitoring and manipulating cellular crosstalk during kidney fibrosis inside a 3D in vitro co-culture

Authors: Nugraha, Bramasta; Moh, Manuel A.; Ponti, Aaron; Emmert, Maximilian Y.; Weibel, Franziska; Hoerstrup, Simon P.; Moll, Solange; Certa, Ulrich; Prunotto, Marco; Pantazis, Periklis

Year: 2017

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/211986

Thesis Human liver organoids for disease modeling of fibrolamellar carcinoma

Narayan, Nicole J.C.; Requena, David; Lalazar, Gadi et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Human liver organoids for disease modeling of fibrolamellar carcinoma

Authors: Narayan, Nicole J.C.; Requena, David; Lalazar, Gadi; Ramos-Espiritu, Lavoisier; Ng, Denise; Levin, Solomon; Shebl, Bassem; Wang, Ruisi; Hammond, William J.; Saltsman, James A.; Gehart, Helmuth; Torbenson, Michael S.; Clevers, Hans; LaQuaglia, Michael P.; Simon, Sanford M.

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/592334

Patent us-2023399623-a1

· 2023

Full title: us-2023399623-a1

Year: 2023

Patent us-2023416691-a1

· 2023

Full title: us-2023416691-a1

Year: 2023

Patent us-2025011728-a1

· 2025

Full title: us-2025011728-a1

Year: 2025

Patent us-2025115878-a1

· 2025

Full title: us-2025115878-a1

Year: 2025

Patent us-11034935-b2

· 2021

Full title: us-11034935-b2

Year: 2021

Patent us-2016282338-a1

· 2016

Full title: us-2016282338-a1

Year: 2016

Patent us-2016030638-a1

· 2016

Full title: us-2016030638-a1

Year: 2016

Patent us-2017002330-a1

· 2017

Full title: us-2017002330-a1

Year: 2017

Patent us-2016369238-a1

· 2016

Full title: us-2016369238-a1

Year: 2016

Patent us-2016348052-a1

· 2016

Full title: us-2016348052-a1

Year: 2016

Patent us-2017166870-a1

· 2017

Full title: us-2017166870-a1

Year: 2017

Patent us-2017188554-a1

· 2017

Full title: us-2017188554-a1

Year: 2017

Patent us-2018016548-a1

· 2018

Full title: us-2018016548-a1

Year: 2018

Patent us-2017088807-a1

· 2017

Full title: us-2017088807-a1

Year: 2017

Patent us-2017292117-a1

· 2017

Full title: us-2017292117-a1

Year: 2017

Patent us-2018059096-a1

· 2018

Full title: us-2018059096-a1

Year: 2018

Patent us-2018066233-a1

· 2018

Full title: us-2018066233-a1

Year: 2018

Patent us-2018112183-a1

· 2018

Full title: us-2018112183-a1

Year: 2018

Patent us-2019350192-a1

· 2019

Full title: us-2019350192-a1

Year: 2019

Patent us-2020010797-a1

· 2020

Full title: us-2020010797-a1

Year: 2020

Patent us-2020115667-a1

· 2020

Full title: us-2020115667-a1

Year: 2020

Patent us-2019367869-a1

· 2019

Full title: us-2019367869-a1

Year: 2019

Patent us-2020231938-a1

· 2020

Full title: us-2020231938-a1

Year: 2020

Patent us-2020269234-a1

· 2020

Full title: us-2020269234-a1

Year: 2020

Patent us-2021317416-a1

· 2021

Full title: us-2021317416-a1

Year: 2021

Patent us-8617815-b2

· 2013

Full title: us-8617815-b2

Year: 2013

Patent us-8912386-b2

· 2014

Full title: us-8912386-b2

Year: 2014

Patent us-8658353-b2

· 2014

Full title: us-8658353-b2

Year: 2014

Patent us-8417465-b2

· 2013

Full title: us-8417465-b2

Year: 2013

Patent us-9222932-b2

· 2015

Full title: us-9222932-b2

Year: 2015

Patent us-7989675-b2

· 2011

Full title: us-7989675-b2

Year: 2011

Patent us-9631169-b2

· 2017

Full title: us-9631169-b2

Year: 2017

Patent us-9441202-b2

· 2016

Full title: us-9441202-b2

Year: 2016

Patent us-9284531-b2

· 2016

Full title: us-9284531-b2

Year: 2016

Patent us-9701938-b2

· 2017

Full title: us-9701938-b2

Year: 2017

Patent us-re39337-e

· 2006

Full title: us-re39337-e

Year: 2006

Patent us-9765301-b2

· 2017

Full title: us-9765301-b2

Year: 2017

Patent us-9932559-b2

· 2018

Full title: us-9932559-b2

Year: 2018

Patent us-2021301261-a1

· 2021

Full title: us-2021301261-a1

Year: 2021

Patent us-2022106570-a1

· 2022

Full title: us-2022106570-a1

Year: 2022

Patent us-2022145266-a1

· 2022

Full title: us-2022145266-a1

Year: 2022

Patent us-2022315902-a1

· 2022

Full title: us-2022315902-a1

Year: 2022

Patent us-2023323308-a1

· 2023

Full title: us-2023323308-a1

Year: 2023

Patent us-11060067-b2

· 2021

Full title: us-11060067-b2

Year: 2021

Patent us-11299714-b2

· 2022

Full title: us-11299714-b2

Year: 2022

Patent us-11534753-b2

· 2022

Full title: us-11534753-b2

Year: 2022

Patent us-11976304-b2

· 2024

Full title: us-11976304-b2

Year: 2024

Patent us-12129492-b2

· 2024

Full title: us-12129492-b2

Year: 2024

Patent us-12104174-b2

· 2024

Full title: us-12104174-b2

Year: 2024

Patent us-12247227-b2

· 2025

Full title: us-12247227-b2

Year: 2025

Patent us-12441988-b2

· 2025

Full title: us-12441988-b2

Year: 2025

Patent us-2003028911-a1

· 2003

Full title: us-2003028911-a1

Year: 2003

Patent us-2004029153-a1

· 2004

Full title: us-2004029153-a1

Year: 2004

Patent us-2005208468-a1

· 2005

Full title: us-2005208468-a1

Year: 2005

Patent us-2006194320-a1

· 2006

Full title: us-2006194320-a1

Year: 2006

Patent us-2005084914-a1

· 2005

Full title: us-2005084914-a1

Year: 2005

Patent us-2006258000-a1

· 2006

Full title: us-2006258000-a1

Year: 2006

Patent us-2007231901-a1

· 2007

Full title: us-2007231901-a1

Year: 2007

Patent us-2007155009-a1

· 2007

Full title: us-2007155009-a1

Year: 2007

Patent us-2009220995-a1

· 2009

Full title: us-2009220995-a1

Year: 2009

Patent us-2010093077-a1

· 2010

Full title: us-2010093077-a1

Year: 2010

Patent us-2009235368-a1

· 2009

Full title: us-2009235368-a1

Year: 2009

Patent us-2009202471-a1

· 2009

Full title: us-2009202471-a1

Year: 2009

Patent us-2011118143-a1

· 2011

Full title: us-2011118143-a1

Year: 2011

Patent us-2012009671-a1

· 2012

Full title: us-2012009671-a1

Year: 2012

Patent us-2010129854-a1

· 2010

Full title: us-2010129854-a1

Year: 2010

Patent us-2011318730-a1

· 2011

Full title: us-2011318730-a1

Year: 2011

Patent us-2012064537-a1

· 2012

Full title: us-2012064537-a1

Year: 2012

Patent us-2012180141-a1

· 2012

Full title: us-2012180141-a1

Year: 2012

Patent us-2012115226-a1

· 2012

Full title: us-2012115226-a1

Year: 2012

Patent us-2014106452-a1

· 2014

Full title: us-2014106452-a1

Year: 2014

Patent us-2013189327-a1

· 2013

Full title: us-2013189327-a1

Year: 2013

Patent us-2014342445-a1

· 2014

Full title: us-2014342445-a1

Year: 2014

Patent us-2014142370-a1

· 2014

Full title: us-2014142370-a1

Year: 2014

Patent us-2015184125-a1

· 2015

Full title: us-2015184125-a1

Year: 2015

Patent us-2011104658-a1

· 2011

Full title: us-2011104658-a1

Year: 2011

Patent us-2015268223-a1

· 2015

Full title: us-2015268223-a1

Year: 2015

2. Data Extraction

0/1033 extracted

Paper

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Papadopoulos, Nicholas; Martin, Joel; Ruan, Qin et al. · 2012

Full title: Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Authors: Papadopoulos, Nicholas; Martin, Joel; Ruan, Qin; Rafique, Ashique; Rosconi, Michael; Shi, Ergang; Pyles, Erica; Yancopoulos, George D.; Stahl, Neil; Wiegand, Stanley J.

DOI: https://doi.org/10.1007/s10456-011-9249-6

Paper

Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Abdelfatah, Sara; Naß, Janine; Knorz, Caroline et al. · 2021

Full title: Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Authors: Abdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan‐Heiner; Efferth, Thomas

DOI: https://doi.org/10.1007/s10565-021-09599-9

Paper

Cellulose-based hydrogel materials: chemistry, properties and their prospective applications

Kabir, S M Fijul; Sikdar, Partha; Haque, Bazle Z. et al. · 2018

Full title: Cellulose-based hydrogel materials: chemistry, properties and their prospective applications

Authors: Kabir, S M Fijul; Sikdar, Partha; Haque, Bazle Z.; Bhuiyan, M. A. Rahman; Ali, Ayub; Islam, Md. Nurul

DOI: https://doi.org/10.1007/s40204-018-0095-0

Paper

Mesenchymal stem cells and immunomodulation: current status and future prospects

Gao, Fei; Chiu, Sheng‐Hao; Motan, Daniyal et al. · 2016

Full title: Mesenchymal stem cells and immunomodulation: current status and future prospects

Authors: Gao, Fei; Chiu, Sheng‐Hao; Motan, Daniyal; Zhang, Z.; Chen, L.; Ji, H-L; Tse, Hung‐Fat; Fu, Q-L; Lian, Qizhou

DOI: https://doi.org/10.1038/cddis.2015.327

Paper

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Li, Hongyi; Yang, Yang; Hong, Weiqi et al. · 2020

Full title: Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Authors: Li, Hongyi; Yang, Yang; Hong, Weiqi; Huang, Mengyuan; Wu, Min; Zhao, Xia

DOI: https://doi.org/10.1038/s41392-019-0089-y

Paper

Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Cao, Huấn; Duan, Lixia; Zhang, Yan et al. · 2021

Full title: Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Authors: Cao, Huấn; Duan, Lixia; Zhang, Yan; Cao, Jun; Zhang, Kun

DOI: https://doi.org/10.1038/s41392-021-00830-x

Paper

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Slyper, Michal; Porter, Caroline; Ashenberg, Orr et al. · 2020

Full title: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

DOI: https://doi.org/10.1038/s41591-020-0844-1

Paper

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Bakken, Trygve E.; Jorstad, Nikolas L.; Hu, Qiwen et al. · 2021

Full title: Comparative cellular analysis of motor cortex in human, marmoset and mouse

DOI: https://doi.org/10.1038/s41586-021-03465-8

Paper

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

Keller, Gordon · 2005

Full title: Embryonic stem cell differentiation: emergence of a new era in biology and medicine

Authors: Keller, Gordon

DOI: https://doi.org/10.1101/gad.1303605

Paper

Intestinal permeability – a new target for disease prevention and therapy

Bischoff, Stephan C.; Barbara, Giovanni; Buurman, Wim A. et al. · 2014

Full title: Intestinal permeability – a new target for disease prevention and therapy

Authors: Bischoff, Stephan C.; Barbara, Giovanni; Buurman, Wim A.; Ockhuizen, Theo; Schulzke, Jörg–Dieter; Sérino, Matteo; Tilg, Herbert; Watson, Alastair J.M.; Wells, Jerry M.

DOI: https://doi.org/10.1186/s12876-014-0189-7

Paper

CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

Lopes‐Pacheco, Miquéias · 2020

Full title: CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

Authors: Lopes‐Pacheco, Miquéias

DOI: https://doi.org/10.3389/fphar.2019.01662

Paper

Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases

Dodina, Maria; Gurtsieva, Dzerassa; Karabelsky, Alexander et al. · 2024

Full title: Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases

Authors: Dodina, Maria; Gurtsieva, Dzerassa; Karabelsky, Alexander; Minskaia, Ekaterina

DOI: https://doi.org/10.3389/fcell.2024.1455140

Paper

A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds

Reddy, M. Sai Bhargava; Ponnamma, Deepalekshmi; Choudhary, Rajan et al. · 2021

Full title: A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds

Authors: Reddy, M. Sai Bhargava; Ponnamma, Deepalekshmi; Choudhary, Rajan; Sadasivuni, Kishor Kumar

DOI: https://doi.org/10.3390/polym13071105

Paper

Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

Ganesan, Anand K.; Ho, Hsiang; Bodemann, Brian O. et al. · 2008

Full title: Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

DOI: https://doi.org/10.1371/journal.pgen.1000298

Paper

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

Spaeth, Erika L.; Dembinski, Jennifer L.; Sasser, A. Kate et al. · 2009

Full title: Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

Authors: Spaeth, Erika L.; Dembinski, Jennifer L.; Sasser, A. Kate; Watson, Keri; Klopp, Ann H.; Hall, Brett M.; Andreeff, Michael; Marini, Frank C.

DOI: https://doi.org/10.1371/journal.pone.0004992

Paper

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

Löscher, Wolfgang; Potschka, Heidrun · 2004

Full title: Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

Authors: Löscher, Wolfgang; Potschka, Heidrun

DOI: https://doi.org/10.1602/neurorx.2.1.86

Paper

Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery

Alavijeh, Mohammad S.; Chishty, Mansoor; Qaiser, M. Zeeshan et al. · 2005

Full title: Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery

Authors: Alavijeh, Mohammad S.; Chishty, Mansoor; Qaiser, M. Zeeshan; Palmer, Alan M.

DOI: https://doi.org/10.1602/neurorx.2.4.554

Paper

Magnetic nanoparticles for gene and drug delivery

Dobson, Jon · 2008

Full title: Magnetic nanoparticles for gene and drug delivery

Authors: Dobson, Jon

DOI: https://doi.org/10.2147/ijn.s1608

Paper

Is It Time to Start Transitioning From 2D to 3D Cell Culture?

Jensen, Caleb; Teng, Yong · 2020

Full title: Is It Time to Start Transitioning From 2D to 3D Cell Culture?

Authors: Jensen, Caleb; Teng, Yong

DOI: https://doi.org/10.3389/fmolb.2020.00033

Paper

Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Szymański, Paweł; Markowicz-Piasecka, Magdalena; Mikiciuk‐Olasik, Elżbieta · 2011

Full title: Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Authors: Szymański, Paweł; Markowicz-Piasecka, Magdalena; Mikiciuk‐Olasik, Elżbieta

DOI: https://doi.org/10.3390/ijms13010427

Paper

Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Jurga, Agnieszka M.; Paleczna, Martyna; Kuter, Katarzyna · 2020

Full title: Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Authors: Jurga, Agnieszka M.; Paleczna, Martyna; Kuter, Katarzyna

DOI: https://doi.org/10.3389/fncel.2020.00198

Paper

In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform

Katt, Moriah E.; Placone, Amanda L.; Wong, Andrew D. et al. · 2016

Full title: In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform

Authors: Katt, Moriah E.; Placone, Amanda L.; Wong, Andrew D.; Xu, Zinnia S.; Searson, Peter C.

DOI: https://doi.org/10.3389/fbioe.2016.00012

Paper

Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Berg, Ellen L. · 2019

Full title: Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Authors: Berg, Ellen L.

DOI: https://doi.org/10.3389/fdata.2019.00047

Paper

Advances in Skin Regeneration Using Tissue Engineering

Vig, Komal; Chaudhari, Atul A.; Tripathi, Shweta et al. · 2017

Full title: Advances in Skin Regeneration Using Tissue Engineering

Authors: Vig, Komal; Chaudhari, Atul A.; Tripathi, Shweta; Dixit, Saurabh; Sahu, Rajnish; Pillai, Shreekumar; Dennis, Vida A.; Singh, Shree R.

DOI: https://doi.org/10.3390/ijms18040789

Paper

Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

Cheung, Randy Chi Fai; Ng, Tzi Bun; Wong, Jack Ho et al. · 2015

Full title: Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

Authors: Cheung, Randy Chi Fai; Ng, Tzi Bun; Wong, Jack Ho; Chan, Wai‐Yee

DOI: https://doi.org/10.3390/md13085156

Paper

Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Tottoli, Erika Maria; Dorati, Rossella; Genta, Ida et al. · 2020

Full title: Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Authors: Tottoli, Erika Maria; Dorati, Rossella; Genta, Ida; Chiesa, Enrica; Pisani, Silvia; Conti, Bice

DOI: https://doi.org/10.3390/pharmaceutics12080735

Paper

Alginate-Based Biomaterials for Regenerative Medicine Applications

Sun, Jinchen; Tan, Huaping · 2013

Full title: Alginate-Based Biomaterials for Regenerative Medicine Applications

Authors: Sun, Jinchen; Tan, Huaping

DOI: https://doi.org/10.3390/ma6041285

Paper

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai, Erik; Astsaturov, Igor; Cukierman, Edna et al. · 2020

Full title: A framework for advancing our understanding of cancer-associated fibroblasts

DOI: https://doi.org/10.1038/s41568-019-0238-1

Paper

Challenges to curing primary brain tumours

Aldape, Kenneth; Brindle, Kevin M.; Chesler, Louis et al. · 2019

Full title: Challenges to curing primary brain tumours

DOI: https://doi.org/10.1038/s41571-019-0177-5

Paper

Engineering dendritic cell vaccines to improve cancer immunotherapy

Perez, Caleb R.; Palma, Michele De · 2019

Full title: Engineering dendritic cell vaccines to improve cancer immunotherapy

Authors: Perez, Caleb R.; Palma, Michele De

DOI: https://doi.org/10.1038/s41467-019-13368-y

Paper

Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells

Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J. et al. · 2018

Full title: Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells

DOI: https://doi.org/10.1038/s41467-018-04761-0

Paper

Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Chen, Min; Yao, Chencheng; Qin, Yingying et al. · 2022

Full title: Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Authors: Chen, Min; Yao, Chencheng; Qin, Yingying; Cui, Xiuhong; Li, Peng; Ji, Zhiyong; Lin, Limei; Wu, Haowei; Zhou, Zhi; Gui, Yaoting; Li, Zheng; Gao, Fei

DOI: https://doi.org/10.1038/s41392-021-00710-4

Paper

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, Marta; Menon, Vilas; Habib, Naomi et al. · 2020

Full title: Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

DOI: https://doi.org/10.1038/s41467-020-19737-2

Paper

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Gordon, David E.; Jang, Gwendolyn Μ.; Bouhaddou, Mehdi et al. · 2020

Full title: A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

DOI: https://doi.org/10.1038/s41586-020-2286-9

Paper

Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

Smits, Jos P.H.; Niehues, Hanna; Rikken, Gijs et al. · 2017

Full title: Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

DOI: https://doi.org/10.1038/s41598-017-12041-y

Paper

Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

Skardal, Aleksander; Murphy, Sean V.; Devarasetty, Mahesh et al. · 2017

Full title: Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

DOI: https://doi.org/10.1038/s41598-017-08879-x

Paper

Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram

Biancalani, Tommaso; Scalia, Gabriele; Buffoni, Lorenzo et al. · 2021

Full title: Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram

DOI: https://doi.org/10.1038/s41592-021-01264-7

Paper

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Lin, Athena W.; Barradas, Marta; Stone, James C. et al. · 1998

Full title: Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Authors: Lin, Athena W.; Barradas, Marta; Stone, James C.; Aelst, Linda Van; Serrano, Manuel; Lowe, Scott W.

DOI: https://doi.org/10.1101/gad.12.19.3008

Paper

Immuno-Detection by sequencing (ID-seq) enables large-scale high-dimensional phenotyping in cells

Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J. et al. · 2017

Full title: Immuno-Detection by sequencing (ID-seq) enables large-scale high-dimensional phenotyping in cells

Authors: Buggenum, Jessie A.G.L. van; Gerlach, Jan P.; Tanis, Sabine E.J.; Hogeweg, Mark; Middelwijk, Jesse; Steen, Ruud van der; Albers, Cornelis A.; Mulder, Klaas W.

DOI: https://doi.org/10.1101/158139

Paper

Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Ewald, Jessica; Titterton, Katherine; Bäuerle, Alex et al. · 2025

Full title: Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

DOI: https://doi.org/10.1101/2025.01.22.634152

Paper

The Hippo pathway: regulators and regulations

Yu, Fa‐Xing; Guan, Kun‐Liang · 2013

Full title: The Hippo pathway: regulators and regulations

Authors: Yu, Fa‐Xing; Guan, Kun‐Liang

DOI: https://doi.org/10.1101/gad.210773.112

Paper

Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

Sukhova, Galina K.; Shi, Guo‐Ping; Simon, Daniel I. et al. · 1998

Full title: Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

Authors: Sukhova, Galina K.; Shi, Guo‐Ping; Simon, Daniel I.; Chapman, Harold A.; Libby, Peter

DOI: https://doi.org/10.1172/jci181

Paper

Liver fibrosis

Bataller, Ramón; Brenner, David A. · 2005

Full title: Liver fibrosis

Authors: Bataller, Ramón; Brenner, David A.

DOI: https://doi.org/10.1172/jci24282

Paper

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Kebriaei, Partow; Singh, Harjeet; Huls, M. Helen et al. · 2016

Full title: Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

DOI: https://doi.org/10.1172/jci86721

Paper

Generation and testing of clinical-grade exosomes for pancreatic cancer

Mendt, Mayela Carolina; Kamerkar, Sushrut; Sugimoto, Hikaru et al. · 2018

Full title: Generation and testing of clinical-grade exosomes for pancreatic cancer

DOI: https://doi.org/10.1172/jci.insight.99263

Paper

Bone regeneration: current concepts and future directions

Dimitriou, Rozalia; Jones, Elena; McGonagle, Dennis et al. · 2011

Full title: Bone regeneration: current concepts and future directions

Authors: Dimitriou, Rozalia; Jones, Elena; McGonagle, Dennis; Giannoudis, Peter V.

DOI: https://doi.org/10.1186/1741-7015-9-66

Paper

The hCMEC/D3 cell line as a model of the human blood brain barrier

Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre‐Olivier · 2013

Full title: The hCMEC/D3 cell line as a model of the human blood brain barrier

Authors: Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre‐Olivier

DOI: https://doi.org/10.1186/2045-8118-10-16

Paper

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

Hinderliter, Paul M.; Minard, Kevin R.; Orr, Galya et al. · 2010

Full title: ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

Authors: Hinderliter, Paul M.; Minard, Kevin R.; Orr, Galya; Chrisler, William; Thrall, Brian D.; Pounds, Joel G.; Teeguarden, Justin

DOI: https://doi.org/10.1186/1743-8977-7-36

Paper

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Vinci, Maria; Gowan, Sharon; Boxall, Frances et al. · 2012

Full title: Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Authors: Vinci, Maria; Gowan, Sharon; Boxall, Frances; Patterson, Lisa; Zimmermann, Miriam; Court, William; Lomas, C.; Mendiola, Marta; Hardisson, David; Eccles, Suzanne A.

DOI: https://doi.org/10.1186/1741-7007-10-29

Paper

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Woodruff, Trent M.; Thundyil, John; Tang, Sung‐Chun et al. · 2011

Full title: Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Authors: Woodruff, Trent M.; Thundyil, John; Tang, Sung‐Chun; Sobey, Christopher G.; Taylor, Stephen M.; Arumugam, Thiruma V.

DOI: https://doi.org/10.1186/1750-1326-6-11

Paper

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Carpenter, Anne E.; Jones, Thouis R.; Lamprecht, Michael R. et al. · 2006

Full title: CellProfiler: image analysis software for identifying and quantifying cell phenotypes

DOI: https://doi.org/10.1186/gb-2006-7-10-r100

Paper

Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Seyhan, Attila A. · 2019

Full title: Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Authors: Seyhan, Attila A.

DOI: https://doi.org/10.1186/s41231-019-0050-7

Paper

Organ-on-a-chip: recent breakthroughs and future prospects

Wu, Qirui; Liu, Jinfeng; Wang, Xiaohong et al. · 2020

Full title: Organ-on-a-chip: recent breakthroughs and future prospects

Authors: Wu, Qirui; Liu, Jinfeng; Wang, Xiaohong; Feng, Lingyan; Wu, Jinbo; Zhu, Xiaoli; Wen, Weijia; Gong, Xiuqing

DOI: https://doi.org/10.1186/s12938-020-0752-0

Paper

Tumor microenvironment complexity and therapeutic implications at a glance

Baghban, Roghayyeh; Roshangar, Leila; Jahanban‐Esfahlan, Rana et al. · 2020

Full title: Tumor microenvironment complexity and therapeutic implications at a glance

Authors: Baghban, Roghayyeh; Roshangar, Leila; Jahanban‐Esfahlan, Rana; Seidi, Khaled; Ebrahimi‐Kalan, Abbas; Jaymand, Mehdi; Kolahian, Saeed; Javaheri, Tahereh; Zare, Payman

DOI: https://doi.org/10.1186/s12964-020-0530-4

Paper

Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Abasalizadeh, Farhad; Moghaddam, Sevil Vaghefi; Alizadeh, Effat et al. · 2020

Full title: Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Authors: Abasalizadeh, Farhad; Moghaddam, Sevil Vaghefi; Alizadeh, Effat; Akbari, Elahe; Kashani, Elmira; Fazljou, Seyyed Mohammad Bagher; Torbati, Mohammadali; Akbarzadeh, Abolfazl

DOI: https://doi.org/10.1186/s13036-020-0227-7

Paper

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Zanoni, Michele; Piccinini, Filippo; Arienti, Chiara et al. · 2016

Full title: 3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Authors: Zanoni, Michele; Piccinini, Filippo; Arienti, Chiara; Zamagni, Alice; Santi, Spartaco; Polico, R.; Bevilacqua, Alessandro; Tesei, Anna

DOI: https://doi.org/10.1038/srep19103

Paper

Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

Mathur, Anurag; Loskill, Peter; Shao, Kaifeng et al. · 2015

Full title: Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

DOI: https://doi.org/10.1038/srep08883

Paper

Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

Herland, Anna; Meer, Andries D. van der; Fitzgerald, Edward A. et al. · 2016

Full title: Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

Authors: Herland, Anna; Meer, Andries D. van der; Fitzgerald, Edward A.; Park, Tae‐Eun; Sleeboom, Jelle J. F.; Ingber, Donald E.

DOI: https://doi.org/10.1371/journal.pone.0150360

Thesis

Utilization of Intestinal Monolayers to Study Stem Cell Differentiation and Drug Toxicity

Bieber, Jake Matthew · 2022

Full title: Utilization of Intestinal Monolayers to Study Stem Cell Differentiation and Drug Toxicity

Authors: Bieber, Jake Matthew

DOI: https://escholarship.org/uc/item/0g03x9zz

Thesis

In Vitro Modeling of the Kidney for Drug Transport and Toxicity Testing

Jayagopal, Aishwarya · 2017

Full title: In Vitro Modeling of the Kidney for Drug Transport and Toxicity Testing

Authors: Jayagopal, Aishwarya

DOI: https://escholarship.org/uc/item/4tc82959

Thesis

Development of micro-physiological multi-organ-on-chip platforms

Agrawal, Gaurav · 2018

Full title: Development of micro-physiological multi-organ-on-chip platforms

Authors: Agrawal, Gaurav

DOI: https://escholarship.org/uc/item/68k0q8ph

Thesis

Stem cell derived organoids and RNA virus pathogenesis

Simoneau, Camille · 2021

Full title: Stem cell derived organoids and RNA virus pathogenesis

Authors: Simoneau, Camille

DOI: https://escholarship.org/uc/item/3sw4926b

Thesis

3D BioPrinting of Cardiac Micro-Tissues

Kleinemolen, Kathleen · 2021

Full title: 3D BioPrinting of Cardiac Micro-Tissues

Authors: Kleinemolen, Kathleen

DOI: https://escholarship.org/uc/item/53x8j44b

Thesis

Development of Tools for Whole-Organism High-Throughput Screening

Liu, Harrison Yi · 2016

Full title: Development of Tools for Whole-Organism High-Throughput Screening

Authors: Liu, Harrison Yi

DOI: https://escholarship.org/uc/item/8bn862xw

Thesis

Development of 3D Cell-Based Assay for High Throughput Screening of Cancer Drugs

Xin, Xin · 2017

Full title: Development of 3D Cell-Based Assay for High Throughput Screening of Cancer Drugs

Authors: Xin, Xin

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1492700405342723

Thesis

Modeling Liver Diseases Using Hepatic Cell Microarrays

Roth, Alexander David · 2018

Full title: Modeling Liver Diseases Using Hepatic Cell Microarrays

Authors: Roth, Alexander David

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=csu1544719407531728

Thesis

Evaluating the use of Cryopreserved Hepatocytes for the Prediction of In Vivo Hepatic Clearance

Eng, Heather S. · 2004

Full title: Evaluating the use of Cryopreserved Hepatocytes for the Prediction of In Vivo Hepatic Clearance

Authors: Eng, Heather S.

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=toledo1091638312

Thesis

In vitro 3D fluorescent cell-based assay reporting gene regulation for high-throughput drug screening

Li, You · 2022

Full title: In vitro 3D fluorescent cell-based assay reporting gene regulation for high-throughput drug screening

Authors: Li, You

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1650589879349223

Thesis

Statistical Analysis of High Content Screening Data

Jacques, Richard · 2009

Full title: Statistical Analysis of High Content Screening Data

Authors: Jacques, Richard

DOI: https://etheses.whiterose.ac.uk/id/eprint/2220/2/Jacques%2C_Richard.pdf

Thesis

Validation of a Human B-Cell Model to Evaluate Potential Immunotoxicants

Rachakonda, Venkata Sailaja · 2025

Full title: Validation of a Human B-Cell Model to Evaluate Potential Immunotoxicants

Authors: Rachakonda, Venkata Sailaja

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=wright1748670629711161

Thesis

High-capacity in vitro models for the assessment of pain-related mechanisms

Lydia Moll (18643606) · 2024

Full title: High-capacity in vitro models for the assessment of pain-related mechanisms

Authors: Lydia Moll (18643606)

DOI: oai:figshare.com:article/26899609

Thesis

3-D cell-based high-throughput screening for drug discovery and cell culture process development

Zhang, Xudong · 2008

Full title: 3-D cell-based high-throughput screening for drug discovery and cell culture process development

Authors: Zhang, Xudong

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561

Thesis

Generation of an optimized model of iPSC-derived human intestinal organoids for the expression of an intestinal stem cell fluorescent reporter, and a preliminary assessment for its application in high-throughput screening

Wong Valencia, Christian Eduardo · 2021

Authors: Wong Valencia, Christian Eduardo

DOI: https://etheses.whiterose.ac.uk/id/eprint/28701/1/Thesis%20CE%20Wong%20Valencia.pdf

Thesis

Extrapolating from experimental to human studies via the in vitro paradigm

Bowen, Edward Llewellyn · 2015

Full title: Extrapolating from experimental to human studies via the in vitro paradigm

Authors: Bowen, Edward Llewellyn

DOI: https://etheses.whiterose.ac.uk/id/eprint/12539/1/E.L.Bowen%20thesis%20v7.pdf

Thesis

Development of a Gut-on-a-Chip models in a 3D microfluidic platform (OrganoPlate®)

Naumovska, Elena · 2020

Full title: Development of a Gut-on-a-Chip models in a 3D microfluidic platform (OrganoPlate®)

Authors: Naumovska, Elena

DOI: https://etheses.whiterose.ac.uk/id/eprint/26679/1/20200406%20thesis%20v.3%20Final.pdf

Thesis

Human iPSC derived neural cells as models of brain development and as tools in pharmaceutical drug discovery

Anders Lundin (18691306) · 2018

Full title: Human iPSC derived neural cells as models of brain development and as tools in pharmaceutical drug discovery

Authors: Anders Lundin (18691306)

DOI: oai:figshare.com:article/26917729

Thesis

Hepatic 3D spheroids as a model system for drug-induced liver injury and cytochrome P450 induction

Delilah Hendriks (18678418) · 2018

Full title: Hepatic 3D spheroids as a model system for drug-induced liver injury and cytochrome P450 induction

Authors: Delilah Hendriks (18678418)

DOI: oai:figshare.com:article/26906974

Thesis

Development of an immune competent human skin equivalent model of atopic dermatitis for pre-clinical drug testing

Barragan Vazquez, Inmaculada · 2022

Full title: Development of an immune competent human skin equivalent model of atopic dermatitis for pre-clinical drug testing

Authors: Barragan Vazquez, Inmaculada

DOI: https://etheses.whiterose.ac.uk/id/eprint/32613/1/Barragan%20Vazquez_Inmaculada_180112272.pdf

Thesis

Novel human in vitro systems for studies of drug inducted hepatotoxicity

Louise Sivertsson (18678481) · 2012

Full title: Novel human in vitro systems for studies of drug inducted hepatotoxicity

Authors: Louise Sivertsson (18678481)

DOI: oai:figshare.com:article/26898070

Thesis

The In Vitro Pharmacology of Cannabidivarin (CBDV)

Le, Jennifer · 2023

Full title: The In Vitro Pharmacology of Cannabidivarin (CBDV)

Authors: Le, Jennifer

DOI: https://hdl.handle.net/10388/14711

Thesis

Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Gagg, Hannah Jane · 2023

Full title: Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Authors: Gagg, Hannah Jane

DOI: https://etheses.whiterose.ac.uk/id/eprint/35177/1/HannahGagg_Thesis_Final_JULY24.pdf

Thesis

Danio rerio as a model of serious human diseases

Hason, Martina · 2022

Full title: Danio rerio as a model of serious human diseases

Authors: Hason, Martina

DOI: http://hdl.handle.net/20.500.11956/175636

Thesis

Defined matrices for epithelial organoid culture and disease modelling

Rezakhani, Saba · 2021

Full title: Defined matrices for epithelial organoid culture and disease modelling

Authors: Rezakhani, Saba

DOI: https://infoscience.epfl.ch/handle/20.500.14299/181177

Thesis

Design and validation of bioorthogonal probes for cellular disease models

D'Alessandro, Pier Luca · 2019

Full title: Design and validation of bioorthogonal probes for cellular disease models

Authors: D'Alessandro, Pier Luca

DOI: https://infoscience.epfl.ch/handle/20.500.14299/162248

Thesis

Intestinal stem cells differentiation and its application in cancer therapy

Norkin, Maxim · 2021

Full title: Intestinal stem cells differentiation and its application in cancer therapy

Authors: Norkin, Maxim

DOI: https://infoscience.epfl.ch/handle/20.500.14299/183214

Thesis

Bioengineering functional organoid models across scales

Hübscher, Tania · 2024

Full title: Bioengineering functional organoid models across scales

Authors: Hübscher, Tania

DOI: https://infoscience.epfl.ch/handle/20.500.14299/207102

Thesis

Bioengineering approaches to emulate the stem cell niche

Höhnel, Sylke · 2015

Full title: Bioengineering approaches to emulate the stem cell niche

Authors: Höhnel, Sylke

DOI: https://infoscience.epfl.ch/handle/20.500.14299/110539

Thesis

Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

Woodruff, Kristina Pan · 2017

Full title: Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

Authors: Woodruff, Kristina Pan

DOI: https://infoscience.epfl.ch/handle/20.500.14299/141458

Thesis

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

May, LT; Bartolo, BA; Harrison, DG et al. · 2023

Full title: Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

Authors: May, LT; Bartolo, BA; Harrison, DG; Guzik, T; Drummond, GR; Figtree, GA; Ritchie, RH; Rye, KA; De Haan, JB

DOI: https://hdl.handle.net/11343/334908

Thesis

Optimizing Stem Cell Models of the Human Gut-immune Barriers

Piryaei, Masoumeh · 2024

Full title: Optimizing Stem Cell Models of the Human Gut-immune Barriers

Authors: Piryaei, Masoumeh

DOI: https://hdl.handle.net/11343/345315

Thesis

Novel approaches using human induced pluripotent stem cells and microRNAs in the development of relevant human hepatocyte models for drug-induced liver injury

Kia, Richard

Full title: Novel approaches using human induced pluripotent stem cells and microRNAs in the development of relevant human hepatocyte models for drug-induced liver injury

Authors: Kia, Richard

DOI: https://livrepository.liverpool.ac.uk/2010059/1/KiaRic_Oct2014_2010059.pdf

Thesis

Determinants of transcriptional regulation of transport and oxidative processes in human model systems

Williamson, Beth

Full title: Determinants of transcriptional regulation of transport and oxidative processes in human model systems

Authors: Williamson, Beth

DOI: https://livrepository.liverpool.ac.uk/15053/1/WilliamsonBet_Sep2013_15053.pdf

Thesis

The role of non-myocytes in drug-induced cardiovascular toxicity

Ravenscroft, Stephanie

Full title: The role of non-myocytes in drug-induced cardiovascular toxicity

Authors: Ravenscroft, Stephanie

DOI: https://livrepository.liverpool.ac.uk/2012640/1/RavenscroftSte_Oct2014_2012639_.pdf

Thesis

Development of a Spheroid Model to Investigate Drug-Induced Liver Injury

Gaskell, H · 2016

Full title: Development of a Spheroid Model to Investigate Drug-Induced Liver Injury

Authors: Gaskell, H

DOI: https://livrepository.liverpool.ac.uk/3004330/1/200648599_Aug2016.pdf

Thesis

DEVELOPMENT OF NOVEL PROXIMAL TUBULE IN VITRO MODELS TO PREDICT DRUG-INDUCED NEPHROTOXICITY

Tort Piella, A · 2016

Full title: DEVELOPMENT OF NOVEL PROXIMAL TUBULE IN VITRO MODELS TO PREDICT DRUG-INDUCED NEPHROTOXICITY

Authors: Tort Piella, A

DOI: https://livrepository.liverpool.ac.uk/3004444/1/200943662_May2016.pdf

Thesis

Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Bulitta, Jurgen B; Hope, William W; Eakin, Ann E et al. · 2019

Full title: Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Authors: Bulitta, Jurgen B; Hope, William W; Eakin, Ann E; Guina, Tina; Tam, Vincent H; Louie, Arnold; Drusano, George L; Hoover, Jennifer L

DOI: https://livrepository.liverpool.ac.uk/3035713/1/AAC.02307-18.full.pdf

Thesis

Investigating novel methods of enhancing in vitro models of drug induced liver injury

Heslop, James · 2015

Full title: Investigating novel methods of enhancing in vitro models of drug induced liver injury

Authors: Heslop, James

DOI: https://livrepository.liverpool.ac.uk/2053229/1/HeslopJam_Oct2015_2053229.pdf

Thesis

Development of stem cell-derived hepatocyte models

Pridgeon, CS · 2019

Full title: Development of stem cell-derived hepatocyte models

Authors: Pridgeon, CS

DOI: https://livrepository.liverpool.ac.uk/3060785/1/201067795_Aug2019.pdf

Thesis

Developing three-dimensional co-cultures of the small intestinal epithelium with intestinal dendritic cells as a disease model for enteric infections

Johnston, L · 2018

Full title: Developing three-dimensional co-cultures of the small intestinal epithelium with intestinal dendritic cells as a disease model for enteric infections

Authors: Johnston, L

DOI: https://livrepository.liverpool.ac.uk/3029488/1/200566317_Sept2018.pdf

Thesis

Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E et al. · 2020

Full title: Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

DOI: https://livrepository.liverpool.ac.uk/3067231/1/NRDD-18-102V7.pdf

Thesis

Designing and Utilising an in vitro Model to Investigate Cellular Pathways Involved in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease

Cotton, CV · 2019

Full title: Designing and Utilising an in vitro Model to Investigate Cellular Pathways Involved in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease

Authors: Cotton, CV

DOI: https://livrepository.liverpool.ac.uk/3044767/1/200162141_Nov2018.pdf

Thesis

Bioengineering an Optimised in vitro Model of the Outer Blood-Retinal Barrier Under Diabetic-like Conditions for the Screening of Novel Pharmacological Formulations for Diabetic Retinopathy

Lugano, Gaia · 2023

Authors: Lugano, Gaia

DOI: https://livrepository.liverpool.ac.uk/3170980/1/201456216_Mar2023.pdf

Thesis

Evaluating the Role of Mitochondrial Genetics in Adverse-Drug Reactions and the Application of iPSC-Derived Hepatocytes for Modelling Drug-Induced Liver Injury

Cox, Christopher · 2023

Full title: Evaluating the Role of Mitochondrial Genetics in Adverse-Drug Reactions and the Application of iPSC-Derived Hepatocytes for Modelling Drug-Induced Liver Injury

Authors: Cox, Christopher

DOI: https://livrepository.liverpool.ac.uk/3171039/1/201368508_Sep2022.pdf

Thesis

Models of alveolar remodeling in chronic lung disease

Rosmark, Oskar · 2022

Full title: Models of alveolar remodeling in chronic lung disease

Authors: Rosmark, Oskar

DOI: https://lup.lub.lu.se/record/5470e7fe-294e-4fd8-847d-2054d90eaac6

Thesis

Towards improved models for the study of the multi-mechanistic toxicity of drug-induced liver injury

Penman, Sophie · 2020

Full title: Towards improved models for the study of the multi-mechanistic toxicity of drug-induced liver injury

Authors: Penman, Sophie

DOI: https://livrepository.liverpool.ac.uk/3114219/1/200905357_Oct2020.pdf

Thesis

Human iPSC-derived cardiomyocytes as platforms for cardiac disease modeling, therapeutic discovery and safety pharmacology

Chen, Zhifen · 2016

Full title: Human iPSC-derived cardiomyocytes as platforms for cardiac disease modeling, therapeutic discovery and safety pharmacology

Authors: Chen, Zhifen

DOI: https://mediatum.ub.tum.de/1308504

Thesis

Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective

Lin, Christine, author; Khetani, Salman R., advisor; Gustafson, Daniel, committee member et al. · 2018

Full title: Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective

Authors: Lin, Christine, author; Khetani, Salman R., advisor; Gustafson, Daniel, committee member; Kipper, Matthew, committee member; Pagliassotti, Michael, committee member

DOI: https://hdl.handle.net/10217/189267

Thesis

Engineering in vitro models of non-alcoholic fatty liver disease

Davidson, Matthew David, author; Khetani, Salman R., advisor; Chicco, Adam J., committee member et al. · 2017

Full title: Engineering in vitro models of non-alcoholic fatty liver disease

Authors: Davidson, Matthew David, author; Khetani, Salman R., advisor; Chicco, Adam J., committee member; Donahue, Seth W., committee member; Kota, Arun K., committee member

DOI: http://hdl.handle.net/10217/181309

Thesis

Large Scale Integration Of Microengineered Tissue Models For High-Content, High-Throughput Analysis Of Complex Human Physiological Systems

Georgescu, Andrei · 2023

Full title: Large Scale Integration Of Microengineered Tissue Models For High-Content, High-Throughput Analysis Of Complex Human Physiological Systems

Authors: Georgescu, Andrei

DOI: https://repository.upenn.edu/handle/20.500.14332/31621

Thesis

Microfluidic culture of human hepatocytes and endothelial cells with applications in drug toxicity screening

Ware, Brenton R., author; Khetani, Salman R., advisor; Gustafson, Daniel L., committee member et al. · 2018

Full title: Microfluidic culture of human hepatocytes and endothelial cells with applications in drug toxicity screening

Authors: Ware, Brenton R., author; Khetani, Salman R., advisor; Gustafson, Daniel L., committee member; Henry, Charles S., committee member; Twedt, David C., committee member

DOI: https://hdl.handle.net/10217/189305

Thesis

Three dimensional polymer scaffolds for high throughput cell-based assay systems

Cheng, Ke · 2024

Full title: Three dimensional polymer scaffolds for high throughput cell-based assay systems

Authors: Cheng, Ke

DOI: https://openscholar.uga.edu/record/11717/files/cheng_ke_200808_phd.pdf

Thesis

Brain-on-a-chip toward neurological diseases' drug discovery

Ndyabawe, Kenneth · 2024

Full title: Brain-on-a-chip toward neurological diseases' drug discovery

Authors: Ndyabawe, Kenneth

DOI: https://openscholar.uga.edu/record/19939/files/ndyabawe_kenneth_201805_phd.pdf

Thesis

DEVELOPMENT OF A MICROGLIA MORPHOLOGY-BASED POTENCY ASSAY TO ASSESS THE THERAPEUTIC POTENTIAL OF MESENCHYMAL STROMAL CELL DERIVED-EXTRACELLULAR VESICLES IN THE CONTEXT OF NEUROINFLAMMATION

Daga, Kanupriya Rajesh · 2025

Authors: Daga, Kanupriya Rajesh

DOI: https://openscholar.uga.edu/record/26932/files/Daga_uga_0077E_16060.pdf

Thesis

Neurotoxicity screening using human pluripotent stem cell derived neurons and astrocytes for adverse outcome pathway mapping

Wu, Xian · 2024

Full title: Neurotoxicity screening using human pluripotent stem cell derived neurons and astrocytes for adverse outcome pathway mapping

Authors: Wu, Xian

DOI: https://openscholar.uga.edu/record/6907/files/wu_xian_201612_phd.pdf

Thesis

Neural microtissue engineering for high throughput screening in pre-clinical drug discovery

Lai, Yinzhi · 2024

Full title: Neural microtissue engineering for high throughput screening in pre-clinical drug discovery

Authors: Lai, Yinzhi

DOI: https://openscholar.uga.edu/record/17693/files/lai_yinzhi_201112_phd.pdf

Thesis

Modeling treacher collins syndrome and directed differentiation of brown adipocytes from human pluripotent stem cells

Avery, John Welch III · 2024

Full title: Modeling treacher collins syndrome and directed differentiation of brown adipocytes from human pluripotent stem cells

Authors: Avery, John Welch III

DOI: https://openscholar.uga.edu/record/21296/files/avery_john_w_201708_phd.pdf

Thesis

An in vitro hybrid method used to model realistic airway deposition and post-deposition behaviour for orally inhaled products

Huynh, Bao Khanh · 2018

Full title: An in vitro hybrid method used to model realistic airway deposition and post-deposition behaviour for orally inhaled products

Authors: Huynh, Bao Khanh

DOI: http://hdl.handle.net/2123/19699

Thesis

Developing 3D Models of Paediatric Solid Tumours

Bax, Samuel David Peter · 2025

Full title: Developing 3D Models of Paediatric Solid Tumours

Authors: Bax, Samuel David Peter

DOI: https://hdl.handle.net/2123/33851

Thesis

Engineering Culture Conditions of Human Stem Cell-Derived Organoids

Yip, Queenie · 2025

Full title: Engineering Culture Conditions of Human Stem Cell-Derived Organoids

Authors: Yip, Queenie

DOI: https://hdl.handle.net/2123/33859

Thesis

In vitro models of the human intestine for better prediction of drug absorption, pre-systemic metabolism, and bioavailability

Ceylan, Merve · 2025

Full title: In vitro models of the human intestine for better prediction of drug absorption, pre-systemic metabolism, and bioavailability

Authors: Ceylan, Merve

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-551251

Thesis

Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

Ölander, Magnus · 2019

Full title: Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

Authors: Ölander, Magnus

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382406

Thesis

ESTIV questionnaire on the acquisition and use of primary human cells and tissue in toxicology

Sladowski, D.; Combes, R.D.; van der Valk, J.B.F. et al. · 2005

Full title: ESTIV questionnaire on the acquisition and use of primary human cells and tissue in toxicology

Authors: Sladowski, D.; Combes, R.D.; van der Valk, J.B.F.; Nawrot, I.; Gut, G.

DOI: https://dspace.library.uu.nl/handle/1874/12169

Thesis

Dynamic microphysiological system chip platform for high-throughput, customizable, and multi-dimensional drug screening

Zhu, Yuxuan; Jiang, Deming; Qiu, Yong et al. · 2024

Full title: Dynamic microphysiological system chip platform for high-throughput, customizable, and multi-dimensional drug screening

Authors: Zhu, Yuxuan; Jiang, Deming; Qiu, Yong; Liu, Xin; Bian, Yuhan; Tian, Shichao; Wang, Xiandi; Hsia, K. Jimmy; Wan, Hao; Zhuang, Liujing; Wang, Ping

DOI: https://hdl.handle.net/10356/179633

Thesis

Regulatory acceptance and use of 3R models: a multilevel perspective

Schiffelers, M.J.W.A.; Blaauboer, B.J.; Hendriksen, C.F.M. et al. · 2012

Full title: Regulatory acceptance and use of 3R models: a multilevel perspective

Authors: Schiffelers, M.J.W.A.; Blaauboer, B.J.; Hendriksen, C.F.M.; Bakker, W.E.

DOI: https://dspace.library.uu.nl/handle/1874/273325

Thesis

The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

Blaauboer, B.J.; Boekelheide, K.; Clewell, H.J. et al. · 2012

Full title: The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

DOI: https://dspace.library.uu.nl/handle/1874/274139

Thesis

Effects of the introducttion of in vitro assays on the use of experimental animals in pharmacological research

Verbost, P.M.; van der Valk, J.B.F.; Hendriksen, C.F.M. · 2007

Full title: Effects of the introducttion of in vitro assays on the use of experimental animals in pharmacological research

Authors: Verbost, P.M.; van der Valk, J.B.F.; Hendriksen, C.F.M.

DOI: https://dspace.library.uu.nl/handle/1874/26133

Thesis

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

Nantasanti, Sathidpak; Spee, Bart; Kruitwagen, Hedwig S et al. · 2015

Full title: Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

DOI: https://dspace.library.uu.nl/handle/1874/327197

Thesis

Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M. et al. · 2011

Full title: Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

Authors: Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M.; Hekkert, M.P.; Schellekens, H.

DOI: https://dspace.library.uu.nl/handle/1874/314494

Thesis

Stem Cell-Derived Systems in Toxicology Assessment

Suter-Dick, Laura; Alves, Paula M.; Blaauboer, Bas J. et al. · 2015

Full title: Stem Cell-Derived Systems in Toxicology Assessment

DOI: https://dspace.library.uu.nl/handle/1874/329523

Thesis

Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Broeders, Jessica J W; Parmentier, Céline; Truisi, Germaine L et al. · 2015

Full title: Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

DOI: https://dspace.library.uu.nl/handle/1874/329931

Thesis

A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity

Nieskens, Tom T G; Peters, Janny G P; Schreurs, Marieke J et al. · 2016

Full title: A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity

DOI: https://dspace.library.uu.nl/handle/1874/329958

Thesis

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Huch, Meritxell; Gehart, Helmuth; van Boxtel, Ruben et al. · 2015

Full title: Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

DOI: https://dspace.library.uu.nl/handle/1874/331481

Thesis

Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

Trumpi, Kari; Egan, David A.; Vellinga, Thomas T. et al. · 2015

Full title: Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

Authors: Trumpi, Kari; Egan, David A.; Vellinga, Thomas T.; Borel Rinkes, Inne H M; Kranenburg, Onno

DOI: https://dspace.library.uu.nl/handle/1874/333255

Thesis

Towards Creating the Perfect In Vitro Cell Model

Jonsson, Malin K B; van Veen, AAB; Synnergren, Jane et al. · 2016

Full title: Towards Creating the Perfect In Vitro Cell Model

Authors: Jonsson, Malin K B; van Veen, AAB; Synnergren, Jane; Becker, Bruno

DOI: https://dspace.library.uu.nl/handle/1874/343073

Thesis

Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J et al. · 2016

Full title: Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?

Authors: Tukker, Anke M; de Groot, Martje W G D M; Wijnolts, Fiona M J; Kasteel, Emma E J; Hondebrink, Laura; Westerink, Remco H S

DOI: https://dspace.library.uu.nl/handle/1874/345305

Thesis

Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut

van Rijn, Jorik M; Schneeberger, Kerstin; Wiegerinck, Caroline L et al. · 2016

Full title: Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut

Authors: van Rijn, Jorik M; Schneeberger, Kerstin; Wiegerinck, Caroline L; Nieuwenhuis, Edward E S; Middendorp, Sabine

DOI: https://dspace.library.uu.nl/handle/1874/345992

Thesis

Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals

Nantasanti, Sathidpak; de Bruin, Alain; Rothuizen, Jan et al. · 2016

Full title: Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals

Authors: Nantasanti, Sathidpak; de Bruin, Alain; Rothuizen, Jan; Penning, Louis C; Schotanus, Baukje A

DOI: https://dspace.library.uu.nl/handle/1874/345896

Thesis

Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Kruitwagen, Hedwig S.; Oosterhoff, Loes A.; Vernooij, Ingrid G.W.H. et al. · 2017

Full title: Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

DOI: https://dspace.library.uu.nl/handle/1874/349600

Thesis

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip

Vriend, Jelle; Nieskens, Tom T G; Vormann, Marianne K et al. · 2018

Full title: Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip

DOI: https://dspace.library.uu.nl/handle/1874/368286

Thesis

A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of IIon Channels in Real-Time

Goversen, Birgit; Becker, Nadine; Stoelzle-Feix, Sonja et al. · 2018

Full title: A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of IIon Channels in Real-Time

Authors: Goversen, Birgit; Becker, Nadine; Stoelzle-Feix, Sonja; Obergrussberger, Alison; Vos, Marc A; van Veen, Toon A B; Fertig, Niels; de Boer, Teun P

DOI: https://dspace.library.uu.nl/handle/1874/363187

Thesis

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

De Sousa, Paul A.; Steeg, Rachel; Wachter, Elisabeth et al. · 2017

Full title: Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

DOI: https://dspace.library.uu.nl/handle/1874/350457

Thesis

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Berkers, Gitte; van Mourik, Peter; Vonk, Annelotte M et al. · 2019

Full title: Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

DOI: https://dspace.library.uu.nl/handle/1874/378368

Thesis

Recellularized native kidney scaffolds as a novel tool in nephrotoxicity screening

Fedecostante, Michele; Westphal, Koen; Buono, Michele et al. · 2018

Full title: Recellularized native kidney scaffolds as a novel tool in nephrotoxicity screening

Authors: Fedecostante, Michele; Westphal, Koen; Buono, Michele; Sanchez Romero, Natalia; Wilmer, Martijn J; Kerkering, Janis; Baptista, Pedro Miguel; Hoenderop, Joost G; Masereeuw, Rosalinde

DOI: https://dspace.library.uu.nl/handle/1874/368269

Thesis

Advances in predictive in vitro models of drug-induced nephrotoxicity

Soo, Joanne Y-C; Jansen, Jitske; Masereeuw, Rosalinde et al. · 2018

Full title: Advances in predictive in vitro models of drug-induced nephrotoxicity

Authors: Soo, Joanne Y-C; Jansen, Jitske; Masereeuw, Rosalinde; Little, Melissa H

DOI: https://dspace.library.uu.nl/handle/1874/369757

Thesis

Long-term expanding human airway organoids for disease modeling

Sachs, Norman; Papaspyropoulos, Angelos; Zomer-van Ommen, Domenique D. et al. · 2019

Full title: Long-term expanding human airway organoids for disease modeling

DOI: https://dspace.library.uu.nl/handle/1874/378838

Thesis

Tubuloids derived from human adult kidney and urine for personalized disease modeling

Schutgens, Frans; Rookmaaker, Maarten B; Margaritis, Thanasis et al. · 2019

Full title: Tubuloids derived from human adult kidney and urine for personalized disease modeling

DOI: https://dspace.library.uu.nl/handle/1874/378205

Thesis

Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients

Jochems, Paulus G M; van Bergenhenegouwen, Jeroen; van Genderen, Anne Metje et al. · 2019

Full title: Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients

DOI: https://dspace.library.uu.nl/handle/1874/380332

Thesis

Tradition, not science, is the basis of animal model selection in translational and applied research

Veening-Griffioen, Désirée H; Ferreira, Guilherme S; Boon, Wouter P C et al. · 2021

Full title: Tradition, not science, is the basis of animal model selection in translational and applied research

Authors: Veening-Griffioen, Désirée H; Ferreira, Guilherme S; Boon, Wouter P C; Gispen-de Wied, Christine C; Schellekens, Huub; Moors, Ellen H M; Van Meer, Peter J K

DOI: https://dspace.library.uu.nl/handle/1874/408501

Thesis

Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine

Kramer, Nina; Pratscher, Barbara; Meneses, Andre M C et al. · 2020

Full title: Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine

DOI: https://dspace.library.uu.nl/handle/1874/408080

Thesis

Intestinal organoids for Cystic Fibrosis research

de Poel, E.; Lefferts, J. W.; Beekman, J. M. · 2020

Full title: Intestinal organoids for Cystic Fibrosis research

Authors: de Poel, E.; Lefferts, J. W.; Beekman, J. M.

DOI: https://dspace.library.uu.nl/handle/1874/394212

Thesis

Kidney-based in vitro models for drug-induced toxicity testing

Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F et al. · 2019

Full title: Kidney-based in vitro models for drug-induced toxicity testing

Authors: Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F; Mihaila, Silvia M; Masereeuw, Rosalinde

DOI: https://dspace.library.uu.nl/handle/1874/394548

Thesis

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis et al. · 2020

Full title: A drug discovery platform to identify compounds that inhibit EGFR triple mutants

DOI: https://dspace.library.uu.nl/handle/1874/410302

Thesis

The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

van Berlo, Damiën; van de Steeg, Evita; Amirabadi, Hossein Eslami et al. · 2021

Full title: The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

Authors: van Berlo, Damiën; van de Steeg, Evita; Amirabadi, Hossein Eslami; Masereeuw, Rosalinde

DOI: https://dspace.library.uu.nl/handle/1874/412501

Thesis

Levelling the Translational Gap for Animal to Human Efficacy Data

Ferreira, Guilherme S.; Veening-Griffioen, Désirée H.; Boon, Wouter P. C. et al. · 2020

Full title: Levelling the Translational Gap for Animal to Human Efficacy Data

Authors: Ferreira, Guilherme S.; Veening-Griffioen, Désirée H.; Boon, Wouter P. C.; Moors, Ellen H. M.; van Meer, Peter J. K.

DOI: https://dspace.library.uu.nl/handle/1874/408505

Thesis

Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment

Tukker, Anke M; Wijnolts, Fiona M J; de Groot, Aart et al. · 2020

Full title: Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment

Authors: Tukker, Anke M; Wijnolts, Fiona M J; de Groot, Aart; Westerink, Remco H S

DOI: https://dspace.library.uu.nl/handle/1874/410154

Thesis

Improving translation by identifying evidence for more human-relevant preclinical strategies

Ritskes-Hoitinga, Merel; Leenaars, Cathalijn; Beumer, Wouter et al. · 2020

Full title: Improving translation by identifying evidence for more human-relevant preclinical strategies

Authors: Ritskes-Hoitinga, Merel; Leenaars, Cathalijn; Beumer, Wouter; Roo, Tineke Coenen De; Stafleu, Frans; Meijboom, Franck L.B.

DOI: https://dspace.library.uu.nl/handle/1874/409049

Thesis

Biomimetic models of the glomerulus

Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P. et al. · 2022

Full title: Biomimetic models of the glomerulus

Authors: Valverde, Marta G.; Mille, Luis S.; Figler, Kianti P.; Cervantes, Ernesto; Li, Vanessa Y.; Bonventre, Joseph V.; Masereeuw, Rosalinde; Zhang, Yu Shrike

DOI: https://dspace.library.uu.nl/handle/1874/419293

Thesis

Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies

Vormann, Marianne K.; Vriend, Jelle; Lanz, Henriëtte L. et al. · 2021

Full title: Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies

DOI: https://dspace.library.uu.nl/handle/1874/411647

Thesis

Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity

Gerber, Lora-Sophie; van Melis, Lennart V J; van Kleef, Regina G D M et al. · 2021

Full title: Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity

Authors: Gerber, Lora-Sophie; van Melis, Lennart V J; van Kleef, Regina G D M; de Groot, Aart; Westerink, Remco H S

DOI: https://dspace.library.uu.nl/handle/1874/413922

Thesis

Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Bouwmeester, Manon C; Tao, Yu; Proença, Susana et al. · 2023

Full title: Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

DOI: https://dspace.library.uu.nl/handle/1874/426917

Thesis

Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Wang, Zhenguo; Faria, João; van der Laan, Luc J.W. et al. · 2022

Full title: Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Authors: Wang, Zhenguo; Faria, João; van der Laan, Luc J.W.; Penning, Louis C.; Masereeuw, Rosalinde; Spee, Bart

DOI: https://dspace.library.uu.nl/handle/1874/424214

Thesis

A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells

Bai, Jing; Fu, Haojie; Bazinet, Lauren et al. · 2020

Full title: A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells

Authors: Bai, Jing; Fu, Haojie; Bazinet, Lauren; Birsner, Amy E.; D'Amato, Robert J.

DOI: https://hdl.handle.net/1721.1/125467

Thesis

Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Schepers, Arnout G; Shan, Jing; Cox, Andrew G et al. · 2022

Full title: Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

Authors: Schepers, Arnout G; Shan, Jing; Cox, Andrew G; Huang, Ada; Evans, Helen; Walesky, Chad; Fleming, Heather E; Goessling, Wolfram; Bhatia, Sangeeta N

DOI: https://hdl.handle.net/1721.1/142801

Thesis

Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes

Michailidis, Eleftherios; Vercauteren, Koen; Mancio-Silva, Liliana et al. · 2021

Full title: Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes

DOI: https://hdl.handle.net/1721.1/136265

Thesis

Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers

Mancio Silva, Liliana; Fleming, Heather; Miller, Alex B et al. · 2020

Full title: Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers

Authors: Mancio Silva, Liliana; Fleming, Heather; Miller, Alex B; Milstein, Stuart; Liebow, Abigail; Haslett, Patrick; Sepp-Lorenzino, Laura; Bhatia, Sangeeta N

DOI: https://hdl.handle.net/1721.1/128861

Thesis

Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

Bein, Amir; Kim, Seongmin; Goyal, Girija et al. · 2022

Full title: Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

DOI: https://hdl.handle.net/1721.1/141283

Thesis

A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors

Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M. et al. · 2015

Full title: A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors

Authors: Zhao, Wen-Ning; Cheng, Chialin; Theriault, Kraig M.; Sheridan, Steven D.; Tsai, Li-Huei; Haggarty, Stephen J.

DOI: http://hdl.handle.net/1721.1/92893

Thesis

A low-cost 3D printed microfluidic bioreactor and imaging chamber for live-organoid imaging

Khan, Ikram; Prabhakar, Anil; Delepine, Chloe et al. · 2022

Full title: A low-cost 3D printed microfluidic bioreactor and imaging chamber for live-organoid imaging

Authors: Khan, Ikram; Prabhakar, Anil; Delepine, Chloe; Tsang, Hayley; Pham, Vincent; Sur, Mriganka

DOI: https://hdl.handle.net/1721.1/142062

Thesis

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

March-Riera, Sandra; Ng, Shengyong; Velmurugan, Soundarapandian et al. · 2014

Full title: A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

DOI: http://hdl.handle.net/1721.1/86118

Thesis

Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Tong, Zhixiang; Martyn, Keir; Yang, Andy et al. · 2022

Full title: Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells

Authors: Tong, Zhixiang; Martyn, Keir; Yang, Andy; Yin, Xiaolei; Mead, Benjamin E.; Joshi, Nitin; Sherman, Nicholas E.; Langer, Robert S.; Karp, Jeffrey M.

DOI: https://hdl.handle.net/1721.1/134688.2

Thesis

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Saha, Krishanu; Jaenisch, Rudolf · 2015

Full title: Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Authors: Saha, Krishanu; Jaenisch, Rudolf

DOI: http://hdl.handle.net/1721.1/96182

Thesis

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

Xu, Jinghai J.; Hendriks, Bart S.; Cosgrove, Benjamin D. et al. · 2011

Full title: Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

DOI: http://hdl.handle.net/1721.1/67046

Thesis

Identification of small molecules for human hepatocyte expansion and iPS differentiation

Shan, Jing; Ross, Nathan T.; Logan, David J. et al. · 2014

Full title: Identification of small molecules for human hepatocyte expansion and iPS differentiation

Authors: Shan, Jing; Ross, Nathan T.; Logan, David J.; Thomas, David; Duncan, Stephen A.; North, Trista E.; Goessling, Wolfram; Carpenter, Anne E.; Schwartz, Robert E.; Bhatia, Sangeeta N

DOI: http://hdl.handle.net/1721.1/86114

Thesis

In vitro models for liver toxicity testing

Soldatow, Valerie Y.; LeCluyse, Edward L.; Griffith, Linda G. et al. · 2014

Full title: In vitro models for liver toxicity testing

Authors: Soldatow, Valerie Y.; LeCluyse, Edward L.; Griffith, Linda G.; Rusyn, Ivan

DOI: http://hdl.handle.net/1721.1/88931

Thesis

Regenerative Medicine: Learning from Past Examples

Couto, Daniela S.; Perez-Breva, Luis; Cooney, Charles L. · 2012

Full title: Regenerative Medicine: Learning from Past Examples

Authors: Couto, Daniela S.; Perez-Breva, Luis; Cooney, Charles L.

DOI: http://hdl.handle.net/1721.1/72661

Thesis

Approaches to in vitro tissue regeneration with application for human disease modeling and drug development

Young, Carissa L.; Lauffenburger, Douglas A.; Griffith, Linda G. et al. · 2015

Full title: Approaches to in vitro tissue regeneration with application for human disease modeling and drug development

Authors: Young, Carissa L.; Lauffenburger, Douglas A.; Griffith, Linda G.; Borenstein, Jeffrey T.; Ebrahimkhani, Mohammad Reza

DOI: http://hdl.handle.net/1721.1/99479

Thesis

Generation of a canine enteroid-derived monolayer model to study gut barrier structure and function

Lopez Cervantes, Veronica Martina · 2022

Full title: Generation of a canine enteroid-derived monolayer model to study gut barrier structure and function

Authors: Lopez Cervantes, Veronica Martina

DOI: https://escholarship.org/uc/item/06f525x4

Thesis

Commercialization of Transiently Transfected Cell Lines for High Throughput Drug Screening and Profiling Applications

Mehta, Kalpita Deepak · 2010

Full title: Commercialization of Transiently Transfected Cell Lines for High Throughput Drug Screening and Profiling Applications

Authors: Mehta, Kalpita Deepak

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1269628794

Thesis

MULTICEULLULAR TUMOR HEMI-SPHEROID: A NOVEL IN VITRO 3D MODEL PLATFORM FOR ACCELERATED DRUG DEVELOPMENT

Kim, Kihwan · 2017

Full title: MULTICEULLULAR TUMOR HEMI-SPHEROID: A NOVEL IN VITRO 3D MODEL PLATFORM FOR ACCELERATED DRUG DEVELOPMENT

Authors: Kim, Kihwan

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1481900120946458

Thesis

3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development

Yen, Terence, Yen · 2017

Full title: 3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development

Authors: Yen, Terence, Yen

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367

Thesis

Tools for translational drug development: Mass cytometry paired cell culture, novel mouse models, and identifying existing model pitfalls

Johnson, Mariah L. · 2021

Full title: Tools for translational drug development: Mass cytometry paired cell culture, novel mouse models, and identifying existing model pitfalls

Authors: Johnson, Mariah L.

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=osu1638519884135162

Thesis

Development and Optimization of a Cell Derived Matrix Assay using Primary Lung Fibroblasts

Adams, Morgan · 2024

Full title: Development and Optimization of a Cell Derived Matrix Assay using Primary Lung Fibroblasts

Authors: Adams, Morgan

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=ucin172139732999051

Thesis

Commercialization of Pre-Clinical Cardiac Safety Using Stem Cell Derived Human Cardiomyocytes

Sethia, Vinay K. · 2011

Full title: Commercialization of Pre-Clinical Cardiac Safety Using Stem Cell Derived Human Cardiomyocytes

Authors: Sethia, Vinay K.

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=case1307731193

Thesis

Human liver in vitro models for evaluation of drug metabolism and disposition

Malin Darnell (18638197) · 2012

Full title: Human liver in vitro models for evaluation of drug metabolism and disposition

Authors: Malin Darnell (18638197)

DOI: oai:figshare.com:article/26921098

Thesis

Novel culture systems to model testicular function and organization

Joao Pedro Lopes (18677530) · 2018

Full title: Novel culture systems to model testicular function and organization

Authors: Joao Pedro Lopes (18677530)

DOI: oai:figshare.com:article/26906248

Thesis

Bioengineered human colon organoids with in vivo-like cellular complexity and function

Mitrofanova, Olga; Nikolaev, Mikhail; Xu, Quan et al. · 2025

Full title: Bioengineered human colon organoids with in vivo-like cellular complexity and function

Authors: Mitrofanova, Olga; Nikolaev, Mikhail; Xu, Quan; Broguiere, Nicolas; Cubela, Irineja; Camp, J. Gray; Bscheider, Michael; Lutolf, Matthias P.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/243339

Thesis

Microwell devices for single-cell analyses

Lindström, Sara · 2009

Full title: Microwell devices for single-cell analyses

Authors: Lindström, Sara

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11665

Thesis

Exploration of novel hepatic In-vitro systems for drug metabolism and pharmacokinetic studies

Lena Preiss (18664720) · 2023

Full title: Exploration of novel hepatic In-vitro systems for drug metabolism and pharmacokinetic studies

Authors: Lena Preiss (18664720)

DOI: oai:figshare.com:article/26924149

Thesis

Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

El Abdellaoui Soussi, Fadoua; Piraino, Francesco; Scholefield, Janine et al. · 2025

Full title: Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

Authors: El Abdellaoui Soussi, Fadoua; Piraino, Francesco; Scholefield, Janine; Hoehnel-Ka, Sylke; Kasendra, Magdalena

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250663

Thesis

Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program

Laurent, Alexis; Scaletta, Corinne; Abdel-Sayed, Philippe et al. · 2025

Full title: Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program

Authors: Laurent, Alexis; Scaletta, Corinne; Abdel-Sayed, Philippe; Michetti, Murielle; de Buys Roessingh, Anthony; Raffoul, Wassim; Hirt-Burri, Nathalie; Applegate, Lee Ann

DOI: https://infoscience.epfl.ch/handle/20.500.14299/253986

Thesis

Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes

Unzu, Carmen; Planet, Evarist; Brandenberg, Nathalie et al. · 2019

Full title: Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes

DOI: https://infoscience.epfl.ch/handle/20.500.14299/154489

Thesis

Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells

Drawnel, Faye M.; Boccardo, Stefano; Prummer, Michael et al. · 2020

Full title: Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells

DOI: https://infoscience.epfl.ch/handle/20.500.14299/165344

Thesis

Progress and potential in organoid research

Rossi, Giuliana; Manfrin, Andrea; Lutolf, Matthias P. · 2018

Full title: Progress and potential in organoid research

Authors: Rossi, Giuliana; Manfrin, Andrea; Lutolf, Matthias P.

DOI: https://infoscience.epfl.ch/handle/20.500.14299/151819

Thesis

Development Strategies for Animal Medical Therapeutics

Morrison, Alexander H; Mason, Nicola J; Paterson, Yvonne · 2023

Full title: Development Strategies for Animal Medical Therapeutics

Authors: Morrison, Alexander H; Mason, Nicola J; Paterson, Yvonne

DOI: https://repository.upenn.edu/handle/20.500.14332/1182

Thesis

Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration

Shin, Min-Kyoung; Bang, Jin Seok; Lee, Jeoung Eun et al. · 2022

Full title: Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration

Authors: Shin, Min-Kyoung; Bang, Jin Seok; Lee, Jeoung Eun; Tran, Hoang-Dai; Park, Genehong; Lee, Dong Ryul; Jo, Junghyun

DOI: https://oist.repo.nii.ac.jp/record/2750/files/Shin-2022-Generation of Skeletal Muscle Organo.pdf

Thesis

Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

Csukovich, Georg (University of Veterinary Medicine, Vienna); Kramer, Nina (University of Veterinary Medicine, Vienna); Pratscher, Barbara (University of Veterinary Medicine, Vienna) et al. · 2023

Full title: Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

DOI: https://phaidra.vetmeduni.ac.at/o:1377

Thesis

The World of Organoids: Gastrointestinal Disease Modelling in the Age of 3R and One Health with Specific Relevance to Dogs and Cats

Csukovich, Georg (University of Veterinary Medicine Vienna); Burgener, Iwan Anton (University of Veterinary Medicine Vienna); Pratscher, Barbara (University of Veterinary Medicine Vienna) · 2022

Full title: The World of Organoids: Gastrointestinal Disease Modelling in the Age of 3R and One Health with Specific Relevance to Dogs and Cats

Authors: Csukovich, Georg (University of Veterinary Medicine Vienna); Burgener, Iwan Anton (University of Veterinary Medicine Vienna); Pratscher, Barbara (University of Veterinary Medicine Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:2082

Thesis

Modeling reproductive and pregnancy-associated tissues using organ-on-chip platforms: challenges, limitations, and the high throughput data frontier

Truong, Nina; Zahra, Abir; Lintao, Ryan C. V. et al. · 2025

Full title: Modeling reproductive and pregnancy-associated tissues using organ-on-chip platforms: challenges, limitations, and the high throughput data frontier

DOI: http://dx.doi.org/10.3389/fbioe.2025.1568389

Thesis

A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip

Moro, Lincoln Gozzi; Guarnier, Lucas Pires; Azevedo, Maurício Fogaça et al. · 2025

Full title: A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip

DOI: http://dx.doi.org/10.3390/cells13242068

Thesis

High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

Norkin, Maxim; Ordóñez-Morán, Paloma; Huelsken, Joerg · 2021

Full title: High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

Authors: Norkin, Maxim; Ordóñez-Morán, Paloma; Huelsken, Joerg

DOI: https://infoscience.epfl.ch/handle/20.500.14299/177705

Thesis

Mechano-modulatory synthetic niches for liver organoid derivation

Sorrentino, Giovanni; Rezakhani, Saba; Yildiz, Ece et al. · 2020

Full title: Mechano-modulatory synthetic niches for liver organoid derivation

Authors: Sorrentino, Giovanni; Rezakhani, Saba; Yildiz, Ece; Nuciforo, Sandro; Heim, Markus H.; Lutolf, Matthias P.; Schoonjans, Kristina

DOI: https://infoscience.epfl.ch/handle/20.500.14299/170291

Thesis

Live mammalian cell arrays

Woodruff, Kristina Pan; Fidalgo, Luis Miguel; Gobaa, Samy et al. · 2013

Full title: Live mammalian cell arrays

Authors: Woodruff, Kristina Pan; Fidalgo, Luis Miguel; Gobaa, Samy; Lutolf, Matthias; Maerkl, Sebastian

DOI: https://infoscience.epfl.ch/handle/20.500.14299/92240

Thesis

Drug discovery through stem cell-based organoid models

Ranga, Adrian; Gjorevski, Nikolche; Lütolf, Matthias · 2014

Full title: Drug discovery through stem cell-based organoid models

Authors: Ranga, Adrian; Gjorevski, Nikolche; Lütolf, Matthias

DOI: https://infoscience.epfl.ch/handle/20.500.14299/101815

Thesis

DEVELOPMENT OF A HUMAN iPSC DERIVED MICROGLIA ASSAY FOR EVALUATION OF TARGET DEPENDENT ACTIVATION AND PHARMACOLOGICAL INHIBITION

Biji, Christy · 2023

Full title: DEVELOPMENT OF A HUMAN iPSC DERIVED MICROGLIA ASSAY FOR EVALUATION OF TARGET DEPENDENT ACTIVATION AND PHARMACOLOGICAL INHIBITION

Authors: Biji, Christy

DOI: http://jhir.library.jhu.edu/handle/1774.2/68748

Thesis

Hurdles in basic science translation

Perry, CJ; Lawrence, AJ · 2020

Full title: Hurdles in basic science translation

Authors: Perry, CJ; Lawrence, AJ

DOI: https://hdl.handle.net/11343/256646

Thesis

A HUMAN BRAIN MICROPHYSIOLOGICAL SYSTEM FOR THE STUDY OF PARKINSON’S DISEASE

Stubenhaus, Bradford Michael · 2018

Full title: A HUMAN BRAIN MICROPHYSIOLOGICAL SYSTEM FOR THE STUDY OF PARKINSON’S DISEASE

Authors: Stubenhaus, Bradford Michael

DOI: http://jhir.library.jhu.edu/handle/1774.2/58691

Thesis

Trends in bone metastasis modeling

Laranga, R; Duchi, S; Ibrahim, T et al. · 2020

Full title: Trends in bone metastasis modeling

Authors: Laranga, R; Duchi, S; Ibrahim, T; Guerrieri, AN; Donati, DM; Lucarelli, E

DOI: https://hdl.handle.net/11343/244361

Thesis

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Huang, JX; Kaeslin, G; Ranall, MV et al. · 2021

Authors: Huang, JX; Kaeslin, G; Ranall, MV; Blaskovich, MA; Becker, B; Butler, MS; Little, MH; Lash, LH; Cooper, MA

DOI: https://hdl.handle.net/11343/261473

Thesis

Application of Urine-Derived Stem Cells to Cellular Modeling in Neuromuscular and Neurodegenerative Diseases

Sato, M; Takizawa, H; Nakamura, A et al. · 2020

Full title: Application of Urine-Derived Stem Cells to Cellular Modeling in Neuromuscular and Neurodegenerative Diseases

Authors: Sato, M; Takizawa, H; Nakamura, A; Turner, BJ; Shabanpoor, F; Aoki, Y

DOI: https://hdl.handle.net/11343/247275

Thesis

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

Hale, LJ; Howden, SE; Phipson, B et al. · 2020

Full title: 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

Authors: Hale, LJ; Howden, SE; Phipson, B; Lonsdale, A; Er, PX; Ghobrial, I; Hosawi, S; Wilson, S; Lawlor, KT; Khan, S; Oshlack, A; Quinlan, C; Lennon, R; Little, MH

DOI: https://hdl.handle.net/11343/253542

Thesis

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Krishnan, R; Park, JA; Seow, CY et al. · 2016

Full title: Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Authors: Krishnan, R; Park, JA; Seow, CY; Lee, PVS; Stewart, AG

DOI: https://hdl.handle.net/11343/116482

Thesis

High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

Choo, N; Ramm, S; Luu, J et al. · 2021

Full title: High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

Authors: Choo, N; Ramm, S; Luu, J; Winter, JM; Selth, LA; Dwyer, AR; Frydenberg, M; Grummet, J; Sandhu, S; Hickey, TE; Tilley, WD; Taylor, RA; Risbridger, GP; Lawrence, MG; Simpson, KJ

DOI: https://hdl.handle.net/11343/281073

Thesis

Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease

Quah, PS; Tran, BM; Corbin, VDA et al. · 2023

Full title: Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease

Authors: Quah, PS; Tran, BM; Corbin, VDA; Chang, JJ-Y; Wong, CY; Diaz-Méndez, A; Hartley, CA; Zeng, W; Hanssen, E; Trifunovic, Z; Reading, PC; Jackson, DC; Vincan, E; Coin, LJM; Deliyannis, G

DOI: https://hdl.handle.net/11343/339334

Thesis

Unprecedented potential for neural drug discovery based on self-organizing hiPSC platforms

Cota-Coronado, A; Durnall, JC; Díaz, NF et al. · 2020

Full title: Unprecedented potential for neural drug discovery based on self-organizing hiPSC platforms

Authors: Cota-Coronado, A; Durnall, JC; Díaz, NF; Thompson, LH; Díaz-Martínez, NE

DOI: https://hdl.handle.net/11343/245942

Thesis

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Ergir, E; Oliver-De La Cruz, J; Fernandes, S et al. · 2023

Full title: Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

DOI: https://hdl.handle.net/11343/335236

Thesis

Investigating the feasibility and ethical implications of phenotypic screening using stem cell-derived tissue models to detect and manage disease

Harris, AR; Walker, MJ; Gilbert, F et al. · 2022

Full title: Investigating the feasibility and ethical implications of phenotypic screening using stem cell-derived tissue models to detect and manage disease

Authors: Harris, AR; Walker, MJ; Gilbert, F; McGivern, P

DOI: https://hdl.handle.net/11343/316082

Thesis

Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Hirokawa, Y; Clarke, J; Palmieri, M et al. · 2021

Full title: Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Authors: Hirokawa, Y; Clarke, J; Palmieri, M; Tan, T; Mouradov, D; Li, S; Lin, C; Li, F; Luo, H; Wu, K; Faux, M; Tan, CW; Lee, M; Gard, G; Gibbs, P; Burgess, AW; Sieber, OM

DOI: https://hdl.handle.net/11343/289714

Thesis

Perspectives on phenotypic screening-Screen Design and Assay Technology Special Interest Group

Pak, C; Simpson, KJ; Weston, AD et al. · 2024

Full title: Perspectives on phenotypic screening-Screen Design and Assay Technology Special Interest Group

Authors: Pak, C; Simpson, KJ; Weston, AD; Cvijic, ME; Evans, K; Napper, AD

DOI: https://hdl.handle.net/11343/351817

Thesis

Airway models in a pandemic: Suitability of models in modeling SARS-CoV-2

Teo, A; Chua, CLL; Chan, LLY · 2022

Full title: Airway models in a pandemic: Suitability of models in modeling SARS-CoV-2

Authors: Teo, A; Chua, CLL; Chan, LLY

DOI: https://hdl.handle.net/11343/307163

Thesis

Human Retinal Organoid Model of Ocular Toxoplasmosis

Ashander, LM; Lidgerwood, GE; Lumsden, AL et al. · 2025

Full title: Human Retinal Organoid Model of Ocular Toxoplasmosis

Authors: Ashander, LM; Lidgerwood, GE; Lumsden, AL; Furtado, JM; Pébay, A; Smith, JR

DOI: https://hdl.handle.net/11343/360229

Thesis

AAV capsid bioengineering in primary human retina models

Westhaus, A; Eamegdool, SS; Fernando, M et al. · 2024

Full title: AAV capsid bioengineering in primary human retina models

DOI: https://hdl.handle.net/11343/344430

Thesis

A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases

Brunet, AA; James, RE; Swanson, P et al. · 2025

Full title: A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases

Authors: Brunet, AA; James, RE; Swanson, P; Carvalho, LS

DOI: https://hdl.handle.net/11343/360367

Thesis

Complementarity and integration of animal and in vitro non-animal pre-clinical model systems� an Australian perspective

· 2025

Full title: Complementarity and integration of animal and in vitro non-animal pre-clinical model systems� an Australian perspective

DOI: https://hdl.handle.net/11343/362325

Thesis

High-Throughput 3-D Cellular Assays Using Destabilized Green Fluorescence Protein

Fraley, Brian · 2010

Full title: High-Throughput 3-D Cellular Assays Using Destabilized Green Fluorescence Protein

Authors: Fraley, Brian

DOI: http://hdl.handle.net/1811/44750

Thesis

Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Heslop, JA; Rowe, C; Walsh, J et al. · 2017

Full title: Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

DOI: https://livrepository.liverpool.ac.uk/3003185/1/Heslop%20hepatocyte%20differentiation.pdf

Thesis

Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

Ravenscroft, Stephanie M; Pointon, Amy; Williams, Awel W et al. · 2016

Full title: Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues

Authors: Ravenscroft, Stephanie M; Pointon, Amy; Williams, Awel W; Cross, Michael J; Sidaway, James E

Thesis

Donor‐Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells

Heslop, J; Kia, R; Pridgeon, C et al. · 2017

Full title: Donor‐Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells

Authors: Heslop, J; Kia, R; Pridgeon, C; Sison-Young, R; Liloglou, T; Elmasry, M; Fenwick, S; Mills, JS; Kitteringham, N; Goldring, C; Park, BK

DOI: https://livrepository.liverpool.ac.uk/3004957/1/R2%20proof%20of%20SCTM%20submission.pdf

Thesis

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Sison-Young, RL; Lauschke, VM; Johann, E et al. · 2017

Full title: A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Thesis

Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment

Kyffin, Jonathan A; Sharma, Parveen; Leedale, Joseph et al. · 2018

Full title: Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment

Authors: Kyffin, Jonathan A; Sharma, Parveen; Leedale, Joseph; Colley, Helen E; Murdoch, Craig; Mistry, Pratibha; Webb, Steven D

DOI: https://livrepository.liverpool.ac.uk/3020420/1/Kyfinn%20et%20al%202018_revised.pdf

Thesis

Stem cell models as an in vitro model for predictive toxicology

Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A et al. · 2019

Full title: Stem cell models as an in vitro model for predictive toxicology

Authors: Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A; Sharma, Parveen; Park, B Kevin; Goldring, Chris EP

DOI: https://livrepository.liverpool.ac.uk/3038014/1/8533_1_art_file_303843_pffps1.pdf

Thesis

Developing a 3D intestinal epithelium model for livestock species

Derricott, H; Luu, L; Fong, WY et al. · 2019

Full title: Developing a 3D intestinal epithelium model for livestock species

Authors: Derricott, H; Luu, L; Fong, WY; Hartley, CS; Johnston, LJ; Armstrong, SD; Randle, N; Duckworth, CA; Campbell, BJ; Wastling, JM; Coombes, JL

DOI: https://livrepository.liverpool.ac.uk/3027174/1/Derricott2018_Article_DevelopingA3DIntestinalEpithel.pdf

Thesis

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, Catherine C; Hendriks, Delilah FG; Moro, Sabrina ML et al. · 2016

Full title: Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Thesis

Multiscale modelling of drug transport and metabolism in liver spheroids

Leedale, JA; Kyffin, Jonathan; Harding, Amy et al. · 2020

Full title: Multiscale modelling of drug transport and metabolism in liver spheroids

Authors: Leedale, JA; Kyffin, Jonathan; Harding, Amy; Colley, Helen; Murdoch, Craig; Sharma, Parveen; Williams, Dominic; Webb, Steven; Bearon, Rachel

DOI: https://livrepository.liverpool.ac.uk/3077573/1/Leedale_IF_2019.pdf

Thesis

Stem cell models as an in vitro model for predictive toxicology.

Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A et al. · 2019

Full title: Stem cell models as an in vitro model for predictive toxicology.

Authors: Lynch, Stephen; Pridgeon, Chris S; Duckworth, Carrie A; Sharma, Parveen; Park, B Kevin; Goldring, Chris EP

DOI: https://livrepository.liverpool.ac.uk/3037014/1/8533_1_art_file_303843_pffps1.pdf

Thesis

A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro

Eyre, Jessica J; Williams, Rachel L; Levis, Hannah J · 2020

Full title: A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro

Authors: Eyre, Jessica J; Williams, Rachel L; Levis, Hannah J

DOI: https://livrepository.liverpool.ac.uk/3104213/1/Elements%20-Unmarked%20Manuscript-JJ%20Eyre%2CRL%20Williams%2CHJ%20Levis%20.pdf

Thesis

Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

Cox, Christopher R; Lynch, Stephen; Goldring, Christopher et al. · 2020

Full title: Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

Authors: Cox, Christopher R; Lynch, Stephen; Goldring, Christopher; Sharma, Parveen

DOI: https://livrepository.liverpool.ac.uk/3112054/1/Cox%20et%20al.pdf

Thesis

Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters

Kilfoil, Peter; Feng, Shuyun Lily; Bassyouni, Asser et al. · 2021

Full title: Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters

Authors: Kilfoil, Peter; Feng, Shuyun Lily; Bassyouni, Asser; Lee, Tiffany; Leishman, Derek; Li, Dingzhou; MacEwan, David J; Sharma, Parveen; Watt, Eric D; Jenkinson, Stephen

DOI: https://livrepository.liverpool.ac.uk/3141575/1/Kilfoil_Stem%20Cell%20Manuscript_Final%20Draft.pdf

Thesis

From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

Malakpour Permlid, Atena · 2020

Full title: From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

Authors: Malakpour Permlid, Atena

DOI: https://lup.lub.lu.se/record/25a3ea4a-d8ec-49d2-bdb7-d2a74473dc17

Thesis

Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19

Assmus, Frauke; Driouich, Jean-Selim; Abdelnabi, Rana et al. · 2022

Full title: Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19

Thesis

Recording from human gut tissue: a major step towards more efficient drug development?

Schemann, Michael · 2011

Full title: Recording from human gut tissue: a major step towards more efficient drug development?

Authors: Schemann, Michael

DOI: https://mediatum.ub.tum.de/1316500

Thesis

Development of an in vitro mechanistic toxicity screening model using cultured hepatocytes

· 2013

Full title: Development of an in vitro mechanistic toxicity screening model using cultured hepatocytes

DOI: http://hdl.handle.net/2263/24162

Thesis

New methodologies for old problems: Tridimensional gastrointestinal organoids and guts-on-a-chip

Sakalem, Marna Eliana [UNESP]; Ribeiro-Paes, João Tadeu [UNESP] · 2018

Full title: New methodologies for old problems: Tridimensional gastrointestinal organoids and guts-on-a-chip

Authors: Sakalem, Marna Eliana [UNESP]; Ribeiro-Paes, João Tadeu [UNESP]

DOI: http://dx.doi.org/10.1016/j.jcol.2017.10.002

Thesis

Intensive care for human hearts in pluripotent stem cell models

Golforoush, Pelin; Schneider, Michael · 2020

Full title: Intensive care for human hearts in pluripotent stem cell models

Authors: Golforoush, Pelin; Schneider, Michael

DOI: https://www.nature.com/articles/s41536-020-0090-7

Thesis

Microsystems manufacturing technologies for pharmaceutical toxicity testing

Macdonald, Niall Patrick · 2013

Full title: Microsystems manufacturing technologies for pharmaceutical toxicity testing

Authors: Macdonald, Niall Patrick

DOI: https://theses.gla.ac.uk/5070/1/Macdonald.pdf

Thesis

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

Conway, JRW; https://orcid.org/0000-0003-3787-277X; Vennin, C et al. · 2017

Full title: Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

DOI: http://hdl.handle.net/1959.4/unsworks_49860

Thesis

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.

Sampaziotis, Fotios; de Brito, Miguel Cardoso; Madrigal, Pedro et al. · 2015

Full title: Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.

DOI: https://www.repository.cam.ac.uk/handle/1810/248631

Thesis

Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint

Liu, Y; Gill, E; Shery Huang, YY · 2017

Full title: Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint

Authors: Liu, Y; Gill, E; Shery Huang, YY

DOI: https://www.repository.cam.ac.uk/handle/1810/263575

Thesis

Challenges and Opportunities in Central Nervous System Drug Discovery

Danon, JJ; Reekie, TA; https://orcid.org/0000-0003-1415-8880 et al. · 2019

Full title: Challenges and Opportunities in Central Nervous System Drug Discovery

Authors: Danon, JJ; Reekie, TA ; https://orcid.org/0000-0003-1415-8880; Kassiou, M

DOI: http://hdl.handle.net/1959.4/unsworks_81549

Thesis

Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties.

Baert, Yoni; De Kock, Joery; Alves-Lopes, João P et al. · 2019

Full title: Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties.

Authors: Baert, Yoni; De Kock, Joery; Alves-Lopes, João P; Söder, Olle; Stukenborg, Jan-Bernd; Goossens, Ellen

DOI: https://www.repository.cam.ac.uk/handle/1810/299749

Thesis

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

Proctor, William R; Foster, Alison J; Vogt, Jennifer et al. · 2017

Full title: Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

DOI: https://www.repository.cam.ac.uk/handle/1810/266637

Thesis

Disease modelling in human organoids.

Lancaster, Madeline A; Huch, Meritxell · 2019

Full title: Disease modelling in human organoids.

Authors: Lancaster, Madeline A; Huch, Meritxell

DOI: https://www.repository.cam.ac.uk/handle/1810/294114

Thesis

A planar impedance sensor for 3D spheroids.

Curto, VF; Ferro, MP; Mariani, F et al. · 2018

Full title: A planar impedance sensor for 3D spheroids.

Authors: Curto, VF; Ferro, MP; Mariani, F; Scavetta, E; Owens, RM

DOI: https://www.repository.cam.ac.uk/handle/1810/287278

Thesis

Functional patient-derived cellular models for neuropsychiatric drug discovery.

Lago, Santiago G; Tomasik, Jakub; Bahn, Sabine · 2021

Full title: Functional patient-derived cellular models for neuropsychiatric drug discovery.

Authors: Lago, Santiago G; Tomasik, Jakub; Bahn, Sabine

DOI: https://www.repository.cam.ac.uk/handle/1810/319750

Thesis

Organoids: a promising new in vitro platform in livestock and veterinary research.

Kar, Soumya K; Wells, Jerry M; Ellen, Esther D et al. · 2021

Full title: Organoids: a promising new in vitro platform in livestock and veterinary research.

Authors: Kar, Soumya K; Wells, Jerry M; Ellen, Esther D; Te Pas, Marinus FW; Madsen, Ole; Groenen, Martien AM; Woelders, Henri

DOI: https://www.repository.cam.ac.uk/handle/1810/319759

Thesis

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.

Georgakopoulos, Nikitas; Prior, Nicole; Angres, Brigitte et al. · 2020

Full title: Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.

DOI: https://www.repository.cam.ac.uk/handle/1810/303876

Thesis

Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Awatade, Nikhil; Wong, Sharon; Jaffe, Adam et al. · 2018

Full title: Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

DOI: http://hdl.handle.net/1959.4/unsworks_54892

Thesis

In Vitro Models for Studying Respiratory Host-Pathogen Interactions.

Barron, Sarah L; Saez, Janire; Owens, Róisín M · 2021

Full title: In Vitro Models for Studying Respiratory Host-Pathogen Interactions.

Authors: Barron, Sarah L; Saez, Janire; Owens, Róisín M

DOI: https://www.repository.cam.ac.uk/handle/1810/329890

Thesis

Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.

Pitsalidis, Charalampos; van Niekerk, Douglas; Moysidou, Chrysanthi-Maria et al. · 2022

Full title: Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.

Authors: Pitsalidis, Charalampos; van Niekerk, Douglas; Moysidou, Chrysanthi-Maria; Boys, Alexander J; Withers, Aimee; Vallet, Romane; Owens, Róisín M

DOI: https://www.repository.cam.ac.uk/handle/1810/342244

Thesis

Immunogenicity of autologous and allogeneic human primary cholangiocyte organoid cellular therapies.

Petrus-Reurer, Sandra; Lei, Winnie; Tysoe, Olivia et al. · 2025

Full title: Immunogenicity of autologous and allogeneic human primary cholangiocyte organoid cellular therapies.

DOI: https://www.repository.cam.ac.uk/handle/1810/385872

Thesis

Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture.

Barron, Sarah L; Wyatt, Owen; O'Connor, Andy et al. · 2024

Full title: Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture.

Authors: Barron, Sarah L; Wyatt, Owen; O'Connor, Andy; Mansfield, David; Suzanne Cohen, E; Witkos, Tomasz M; Strickson, Sam; Owens, Róisín M

DOI: https://www.repository.cam.ac.uk/handle/1810/362890

Thesis

A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer.

Inglebert, Marine; Dettwiler, Martina; Hahn, Kerstin et al. · 2022

Full title: A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer.

DOI: https://www.repository.cam.ac.uk/handle/1810/342593

Thesis

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

Wilson, AA; Ying, L; Liesa, M et al. · 2025

Full title: Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

DOI: https://www.repository.cam.ac.uk/handle/1810/378776

Thesis

Modeling human disease with pluripotent stem cells: from genome association to function.

Merkle, Florian T; Eggan, Kevin · 2025

Full title: Modeling human disease with pluripotent stem cells: from genome association to function.

Authors: Merkle, Florian T; Eggan, Kevin

DOI: https://www.repository.cam.ac.uk/handle/1810/378954

Thesis

Establishing predictive machine learning models for drug responses in patient derived cell culture.

Abdel-Rehim, Abbi; Orhobor, Oghenejokpeme; Griffiths, Gareth et al. · 2025

Full title: Establishing predictive machine learning models for drug responses in patient derived cell culture.

Authors: Abdel-Rehim, Abbi; Orhobor, Oghenejokpeme; Griffiths, Gareth; Soldatova, Larisa; King, Ross D

DOI: https://www.repository.cam.ac.uk/handle/1810/384213

Thesis

Porous scaffolds for in vitro modelling and monitoring of the extracellular matrix

Owens, Roisin · 2025

Full title: Porous scaffolds for in vitro modelling and monitoring of the extracellular matrix

Authors: Owens, Roisin

DOI: https://www.repository.cam.ac.uk/handle/1810/392583

Thesis

Ex-vivo model to stimulate nasal tissue and new therapeutic targets

Patou, Joke · 2011

Full title: Ex-vivo model to stimulate nasal tissue and new therapeutic targets

Authors: Patou, Joke

DOI: https://biblio.ugent.be/publication/8530265

Thesis

How in vitro alterations in cellular energy pathways can overcome obstacles in drug research

Seeland, Swen · 2013

Full title: How in vitro alterations in cellular energy pathways can overcome obstacles in drug research

Authors: Seeland, Swen

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/15626/1/Dissertation_Uni_HD_Swen_Seeland_%28Oktober_2012%29.pdf

Thesis

Toxicogenomic approaches for the prediction of hepatotoxicity in vitro

Hrach, Jens · 2009

Full title: Toxicogenomic approaches for the prediction of hepatotoxicity in vitro

Authors: Hrach, Jens

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/9204/1/Dissertation_Jens_Hrach.pdf

Thesis

Entwicklung von mikrofluidischen Multi-Organ-Zellchipsystemen für die in vitro Metabolisierung und Bestimmung der Toxizität von Substanzen

Theobald, Jannick Florian · 2018

Full title: Entwicklung von mikrofluidischen Multi-Organ-Zellchipsystemen für die in vitro Metabolisierung und Bestimmung der Toxizität von Substanzen

Authors: Theobald, Jannick Florian

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/25215/7/28052018%20Thesis%20Gesamt%20jft.pdf

Thesis

Gen- und Proteinexpressionsanalysen an primären Rattenhepatozyten

Beigel, Jürgen · 2005

Full title: Gen- und Proteinexpressionsanalysen an primären Rattenhepatozyten

Authors: Beigel, Jürgen

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/6103/1/Dissertation.Juergen.Beigel.pdf

Thesis

Human Orthotopic and Metastatic Lung Cancer-on-Chip Models

Hassell, Bryan · 2019

Full title: Human Orthotopic and Metastatic Lung Cancer-on-Chip Models

Authors: Hassell, Bryan

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:39987883

Thesis

Evaluating the Clearance of Common Extra-label Drug Combinations by Turkey Hepatocytes in Primary Culture

Lyster, Samantha · 2020

Full title: Evaluating the Clearance of Common Extra-label Drug Combinations by Turkey Hepatocytes in Primary Culture

Authors: Lyster, Samantha

DOI: https://hdl.handle.net/10214/20732

Thesis

Vascularized, Immune-Infiltrated, and Perfusable Kidney Organoid-on-Chip Models

Kroll, Katharina Theresa · 2023

Full title: Vascularized, Immune-Infiltrated, and Perfusable Kidney Organoid-on-Chip Models

Authors: Kroll, Katharina Theresa

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375560

Thesis

Development of a quick, robust and chemically-defined differentiation protocol from human induced pluripotent stem cells towards cortical neurons to phenotype Alzheimer’s Disease

Kowalski, Alexandra · 2020

Full title: Development of a quick, robust and chemically-defined differentiation protocol from human induced pluripotent stem cells towards cortical neurons to phenotype Alzheimer’s Disease

Authors: Kowalski, Alexandra

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/27918/1/DoctoralThesisAlexandraKowalski2019.pdf

Thesis

Phenotypic High-Throughput Screening to Identify Small-Molecule Inhibitors of Beta-Cell Glucolipotoxicity

Small, Jonnell Candice · 2022

Full title: Phenotypic High-Throughput Screening to Identify Small-Molecule Inhibitors of Beta-Cell Glucolipotoxicity

Authors: Small, Jonnell Candice

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371930

Thesis

Development of a novel human co-culture model to study interactions between intestinal immune and epithelial cells

Steinhauer, Michelle · 2024

Full title: Development of a novel human co-culture model to study interactions between intestinal immune and epithelial cells

Authors: Steinhauer, Michelle

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/34307/1/231020_PhD%20thesis_Michelle%20Steinhauer.pdf

Thesis

Unraveling the Molecular and Cellular Complexities of the Kidney in Health and Disease

Sidhom, Eriene-Heidi · 2019

Full title: Unraveling the Molecular and Cellular Complexities of the Kidney in Health and Disease

Authors: Sidhom, Eriene-Heidi

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42029547

Thesis

Human In Vitro Models of Pediatric Muscular Diseases

Nesmith, Alexander Peyton · 2018

Full title: Human In Vitro Models of Pediatric Muscular Diseases

Authors: Nesmith, Alexander Peyton

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:37944973

Thesis

Elucidating Human Disease Mechanisms Using Innovative Open Microfluidic Platforms

Zeng, Yuting · 2024

Full title: Elucidating Human Disease Mechanisms Using Innovative Open Microfluidic Platforms

Authors: Zeng, Yuting

DOI: https://hdl.handle.net/1773/52441

Thesis

Proteomics informed investigation of human hepatocytes and liver tissue

Handin, Niklas · 2021

Full title: Proteomics informed investigation of human hepatocytes and liver tissue

Authors: Handin, Niklas

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-446954

Thesis

Recreating the microenvironment of the neurovascular unit

Matthiesen, Isabelle · 2022

Full title: Recreating the microenvironment of the neurovascular unit

Authors: Matthiesen, Isabelle

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-310606

Thesis

Development and Characterization of a Human Intestinal Organoid Monolayer Model to Predict Oral Drug Disposition

Arian, Christopher Michael · 2025

Full title: Development and Characterization of a Human Intestinal Organoid Monolayer Model to Predict Oral Drug Disposition

Authors: Arian, Christopher Michael

DOI: https://hdl.handle.net/1773/52855

Thesis

Accelerating the discovery of drugs for Neglected Tropical Diseases using biophysical methods

Opassi, Giulia · 2020

Full title: Accelerating the discovery of drugs for Neglected Tropical Diseases using biophysical methods

Authors: Opassi, Giulia

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408721

Thesis

Insights into Polycystic Kidney Disease : In Vitro Models, Proteome Analyses and Drug Repurposing

Meyer, Alina · 2025

Full title: Insights into Polycystic Kidney Disease : In Vitro Models, Proteome Analyses and Drug Repurposing

Authors: Meyer, Alina

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-564615

Thesis

Advanced In Vitro Systems for Studies of Drug Disposition in the Human Liver

Mickols, Evgeniya · 2025

Full title: Advanced In Vitro Systems for Studies of Drug Disposition in the Human Liver

Authors: Mickols, Evgeniya

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-548596

Thesis

Microfluidic in vitro model to study cell mechanisms and drug efficacy

Nishanth Venugopal Menon · 2015

Full title: Microfluidic in vitro model to study cell mechanisms and drug efficacy

Authors: Nishanth Venugopal Menon

DOI: https://hdl.handle.net/10356/65723

Thesis

Why animal studies are still being used in drug development. An innovation system perspective

Kooijman, M. · 2013

Full title: Why animal studies are still being used in drug development. An innovation system perspective

Authors: Kooijman, M.

DOI: https://dspace.library.uu.nl/handle/1874/287829

Thesis

Building the colon epithelial microenvironment in vitro for investigation of intestinal disease mechanisms

Massaro, Angelo · 2025

Full title: Building the colon epithelial microenvironment in vitro for investigation of intestinal disease mechanisms

Authors: Massaro, Angelo

DOI: https://hdl.handle.net/1773/52721

Thesis

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report

Basketter, D.A.; Clewell, H.; Kimber, I. et al. · 2012

Full title: A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report

Authors: Basketter, D.A.; Clewell, H.; Kimber, I.; Rossi, A.; Blaauboer, B.J.; Burrier, R.; Daneshian, M.; Eskes, C.; Goldberg, A.; Hasiwa, N.

DOI: https://dspace.library.uu.nl/handle/1874/274141

Thesis

Intestinal organoids as model for cystic fibrosis

Dekkers, J.F. · 2015

Full title: Intestinal organoids as model for cystic fibrosis

Authors: Dekkers, J.F.

DOI: https://dspace.library.uu.nl/handle/1874/321710

Thesis

Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

Marx, Uwe; Andersson, Tommy B; Bahinski, Anthony et al. · 2016

Full title: Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

DOI: https://dspace.library.uu.nl/handle/1874/344409

Thesis

Adult Stem Cell-Derived Kidney Organoids to Model Tissue Physiology and Disease

Schutgens, F.W.G. · 2017

Full title: Adult Stem Cell-Derived Kidney Organoids to Model Tissue Physiology and Disease

Authors: Schutgens, F.W.G.

DOI: https://dspace.library.uu.nl/handle/1874/357191

Thesis

Application of human organoids in ion transport studies

Zomer-van Ommen, D.D. · 2018

Full title: Application of human organoids in ion transport studies

Authors: Zomer-van Ommen, D.D.

DOI: https://dspace.library.uu.nl/handle/1874/364743

Thesis

Optimizing drug discovery by Investigative Toxicology: Current and future trends

Beilmann, Mario; Boonen, Harrie; Czich, Andreas et al. · 2019

Full title: Optimizing drug discovery by Investigative Toxicology: Current and future trends

DOI: https://dspace.library.uu.nl/handle/1874/381420

Thesis

Utilizing organoids to study general and tissue-specific adult stem cell profiles: Exploiting organoid cultures for basic stem cell research

Boonekamp, Kim Elisabeth · 2020

Full title: Utilizing organoids to study general and tissue-specific adult stem cell profiles: Exploiting organoid cultures for basic stem cell research

Authors: Boonekamp, Kim Elisabeth

DOI: https://dspace.library.uu.nl/handle/1874/399221

Thesis

Personalizing CFTR modulator therapies

Berkers, Gitte · 2020

Full title: Personalizing CFTR modulator therapies

Authors: Berkers, Gitte

DOI: https://dspace.library.uu.nl/handle/1874/400837

Thesis

Precision medicine for Cystic Fibrosis using intestinal organoids

Mourik, Peter van · 2021

Full title: Precision medicine for Cystic Fibrosis using intestinal organoids

Authors: Mourik, Peter van

DOI: https://dspace.library.uu.nl/handle/1874/416554

Thesis

Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do

Ribitsch, Iris; Baptista, Pedro M; Lange-Consiglio, Anna et al. · 2020

Full title: Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do

DOI: https://dspace.library.uu.nl/handle/1874/410152

Thesis

Modelling of a wide variety of disease using adult stem cell-derived organoids

Vaart, Jelte Yoran van der · 2022

Full title: Modelling of a wide variety of disease using adult stem cell-derived organoids

Authors: Vaart, Jelte Yoran van der

DOI: https://dspace.library.uu.nl/handle/1874/416576

Thesis

Selection of animal models for drug efficacy

Veening - Griffioen, Desiree · 2023

Full title: Selection of animal models for drug efficacy

Authors: Veening - Griffioen, Desiree

DOI: https://dspace.library.uu.nl/handle/1874/426641

Thesis

Bioengineering hepatic organoids: Development of an alternative model for liver toxicity

Bouwmeester, Manon Christel · 2023

Full title: Bioengineering hepatic organoids: Development of an alternative model for liver toxicity

Authors: Bouwmeester, Manon Christel

DOI: https://dspace.library.uu.nl/handle/1874/433481

Thesis

Crafting Tissue Complexity: Pioneering Layerwise and Volumetric Biofabrication Strategies for Advanced In Vitro Models

Núñez Bernal, Paulina · 2024

Full title: Crafting Tissue Complexity: Pioneering Layerwise and Volumetric Biofabrication Strategies for Advanced In Vitro Models

Authors: Núñez Bernal, Paulina

DOI: https://dspace.library.uu.nl/handle/1874/433677

Thesis

Paving the road towards the Next Generation Risk Assessment: Quantitative in vitro to in vivo extrapolations for the pre-diction of human toxicity based on alternative testing

Fragki, Styliani · 2023

Full title: Paving the road towards the Next Generation Risk Assessment: Quantitative in vitro to in vivo extrapolations for the pre-diction of human toxicity based on alternative testing

Authors: Fragki, Styliani

DOI: https://dspace.library.uu.nl/handle/1874/438153

Thesis

Nasal epithelial cells as model for cystic fibrosis

Rodenburg, Lisa Willemijn · 2024

Full title: Nasal epithelial cells as model for cystic fibrosis

Authors: Rodenburg, Lisa Willemijn

DOI: https://dspace.library.uu.nl/handle/1874/433622

Thesis

In Vitro Porcine (Explant) Colon Culture

de Oliveira Costa, Matheus; Dame, Michael K. · 2024

Full title: In Vitro Porcine (Explant) Colon Culture

Authors: de Oliveira Costa, Matheus; Dame, Michael K.

DOI: https://dspace.library.uu.nl/handle/1874/438349

Thesis

Non-human primates in biomedical research : reasons and alternatives for their use

Pieters, F. · 2007

Full title: Non-human primates in biomedical research : reasons and alternatives for their use

Authors: Pieters, F.

DOI: https://dspace.library.uu.nl/handle/1874/44806

Thesis

Alternatives to animal research: from in vitro to ex vivo liver models

Krüger, Melanie · 2024

Full title: Alternatives to animal research: from in vitro to ex vivo liver models

Authors: Krüger, Melanie

DOI: https://dspace.library.uu.nl/handle/1874/455689

Thesis

Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders

Dutan Polit, Lucia; Eidhof, Ilse; McNeill, Rhiannon V. et al. · 2023

Full title: Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders

DOI: https://dspace.library.uu.nl/handle/1874/459427

Thesis

Dual perspectives: Cellular differentiation in health and disease

DeMartino, Jeffrey Ross · 2024

Full title: Dual perspectives: Cellular differentiation in health and disease

Authors: DeMartino, Jeffrey Ross

DOI: https://dspace.library.uu.nl/handle/1874/456590

Thesis

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

· 2021

Full title: Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

DOI: https://hdl.handle.net/1721.1/133522

Thesis

High throughput measurement and perturbation of tissues and tissue-derived cellular models

Kummerlowe, Conner Samuel · 2023

Full title: High throughput measurement and perturbation of tissues and tissue-derived cellular models

Authors: Kummerlowe, Conner Samuel

DOI: https://hdl.handle.net/1721.1/147420

Thesis

Bioreactor technologies to support liver function in vitro

Neiman, Jaclyn A. Shepard; Hughes, David J.; Griffith, Linda G. et al. · 2015

Full title: Bioreactor technologies to support liver function in vitro

Authors: Neiman, Jaclyn A. Shepard; Hughes, David J.; Griffith, Linda G.; Ebrahimkhani, Mohammad Reza; Raredon, Micha Sam Brickman

DOI: http://hdl.handle.net/1721.1/99380

Thesis

Charakterisierung und Anwendung von in vitro und ex vivo Kultursystemen des oberen und unteren Respirationstraktes zur Erforschung der SARS-CoV-2 Empfänglichkeit bei verschiedenen Spezies unter Berücksichtigung des 3R Grundsatzes

Lockow, Sandra Sina · 2023

Authors: Lockow, Sandra Sina

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-119605

Thesis

In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury

Granitzny, Anne · 2017

Full title: In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury

Authors: Granitzny, Anne

DOI: https://nbn-resolving.org/urn:nbn:de:gbv:95-110521

Thesis

Programmable systems to engineer human tissues and electrophysiological sensors

Parekh, Udit · 2021

Full title: Programmable systems to engineer human tissues and electrophysiological sensors

Authors: Parekh, Udit

DOI: https://escholarship.org/uc/item/0rw1h5q2

Thesis

Development of a scalable in-vivo drug discovery platform allows for deep interrogation of mechanisms of KRAS.G12C inhibitors.

Yu, John Xuzong · 2022

Full title: Development of a scalable in-vivo drug discovery platform allows for deep interrogation of mechanisms of KRAS.G12C inhibitors.

Authors: Yu, John Xuzong

DOI: https://escholarship.org/uc/item/17w596v6

Thesis

Organs and Humans on Chips: Translation, Biomedical Models, and the Political Economy of Innovation

Jeske, Melanie S · 2022

Full title: Organs and Humans on Chips: Translation, Biomedical Models, and the Political Economy of Innovation

Authors: Jeske, Melanie S

DOI: https://escholarship.org/uc/item/1619z088

Thesis

High-content array based screening technology for the identification of factors that regulate cell fate

Brafman, David Adam · 2009

Full title: High-content array based screening technology for the identification of factors that regulate cell fate

Authors: Brafman, David Adam

DOI: https://escholarship.org/uc/item/3gw8w75m

Thesis

HNF4 alpha bioactive ligands discovered by a high- throughput screen for modulators of the human insulin promoter

Kiselyuk, Alice Susan · 2011

Full title: HNF4 alpha bioactive ligands discovered by a high- throughput screen for modulators of the human insulin promoter

Authors: Kiselyuk, Alice Susan

DOI: https://escholarship.org/uc/item/64k4q3gr

Thesis

RAPID 3D BIOPRINTING OF BIOMIMETIC LIVER TISSUES FOR MODELING HEALTHY AND DISEASE STATES IN VITRO

Ma, Xuanyi · 2018

Full title: RAPID 3D BIOPRINTING OF BIOMIMETIC LIVER TISSUES FOR MODELING HEALTHY AND DISEASE STATES IN VITRO

Authors: Ma, Xuanyi

DOI: https://escholarship.org/uc/item/0z647878

Thesis

Micropatterned co-cultures of hepatocytes and nonparenchymal cells : mechanisms of differentiation, dynamics and applications

Khetani, Salman R. · 2006

Full title: Micropatterned co-cultures of hepatocytes and nonparenchymal cells : mechanisms of differentiation, dynamics and applications

Authors: Khetani, Salman R.

DOI: https://escholarship.org/uc/item/9g06w180

Thesis

A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

Nguyen, Vivian V T; Ye, Shicheng; Gkouzioti, Vasiliki et al. · 2022

Full title: A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles

DOI: https://dspace.library.uu.nl/handle/1874/424297

Thesis

Tissue Engineered Bile Ducts for Disease Modeling and Therapy

Wang, Zhenguo; Faria, Joao; Penning, Louis et al. · 2021

Full title: Tissue Engineered Bile Ducts for Disease Modeling and Therapy

Authors: Wang, Zhenguo; Faria, Joao; Penning, Louis; Masereeuw, Roos; Spee, Bart

DOI: https://dspace.library.uu.nl/handle/1874/432277

Thesis

Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants

Amirabadi, Hossein Eslami; Donkers, Joanne M.; Wierenga, Esmée et al. · 2022

Full title: Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants

DOI: https://dspace.library.uu.nl/handle/1874/431716

Thesis

Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro

Pscheid, Ronja; Drent, Esther; Wienke, Judith et al. · 2023

Full title: Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro

Authors: Pscheid, Ronja; Drent, Esther; Wienke, Judith; Strijker, Josephine G.M.; Throsby, Mark; Molenaar, Jan J.

DOI: https://dspace.library.uu.nl/handle/1874/435873

Thesis

New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

Punt, Ans; Bouwmeester, Hans; Blaauboer, Bas J et al. · 2020

Full title: New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

DOI: https://dspace.library.uu.nl/handle/1874/432487

Thesis

Kidney Organoids and Tubuloids

Yousef Yengej, Fjodor A; Jansen, Jitske; Rookmaaker, Maarten B et al. · 2020

Full title: Kidney Organoids and Tubuloids

Authors: Yousef Yengej, Fjodor A; Jansen, Jitske; Rookmaaker, Maarten B; Verhaar, Marianne C; Clevers, Hans

DOI: https://dspace.library.uu.nl/handle/1874/439818

Thesis

Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

Giobbe, Giovanni Giuseppe; Crowley, Claire; Luni, Camilla et al. · 2019

Full title: Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

DOI: https://dspace.library.uu.nl/handle/1874/439401

Thesis

Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

Akbari, Soheil; Sevinç, Gülben Gürhan; Ersoy, Nevin et al. · 2019

Full title: Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

DOI: https://dspace.library.uu.nl/handle/1874/439393

Thesis

Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

Vonk, Annelotte M; van Mourik, Peter; Ramalho, Anabela S et al. · 2020

Full title: Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

DOI: https://dspace.library.uu.nl/handle/1874/440961

Thesis

Organoids for personalized treatment of Cystic Fibrosis: Professional perspectives on the ethics and governance of organoid biobanking

Lensink, Michael A; Boers, Sarah N; Jongsma, Karin R et al. · 2021

Full title: Organoids for personalized treatment of Cystic Fibrosis: Professional perspectives on the ethics and governance of organoid biobanking

Authors: Lensink, Michael A; Boers, Sarah N; Jongsma, Karin R; Carter, Sarah E; van der Ent, Cornelis K; Bredenoord, Annelien L

DOI: https://dspace.library.uu.nl/handle/1874/441358

Thesis

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

Ringel, Till; Frey, Nina; Ringnalda, Femke et al. · 2020

Full title: Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

DOI: https://dspace.library.uu.nl/handle/1874/442165

Thesis

An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells

Lamers, Mart M; van der Vaart, Jelte; Knoops, Kèvin et al. · 2021

Full title: An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells

DOI: https://dspace.library.uu.nl/handle/1874/442177

Thesis

Stem cells, organoids, and organ-on-a-chip models for personalized in vitro drug testing

van Berlo, Damiën; Nguyen, Vivian V.T.; Gkouzioti, Vasiliki et al. · 2021

Full title: Stem cells, organoids, and organ-on-a-chip models for personalized in vitro drug testing

Authors: van Berlo, Damiën; Nguyen, Vivian V.T.; Gkouzioti, Vasiliki; Leineweber, Kirsten; Verhaar, Marianne C.; van Balkom, Bas W.M.

DOI: https://dspace.library.uu.nl/handle/1874/445270

Thesis

Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

Maas, Renee G.C.; Lee, Soah; Harakalova, Magdalena et al. · 2021

Full title: Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

DOI: https://dspace.library.uu.nl/handle/1874/445447

Thesis

Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

De Crignis, Elisa; Hossain, Tanvir; Romal, Shahla et al. · 2021

Full title: Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

DOI: https://dspace.library.uu.nl/handle/1874/445573

Thesis

Development in a Dish—In Vitro Models of Mammalian Embryonic Development

el Azhar, Yasmine; Sonnen, Katharina F. · 2021

Full title: Development in a Dish—In Vitro Models of Mammalian Embryonic Development

Authors: el Azhar, Yasmine; Sonnen, Katharina F.

DOI: https://dspace.library.uu.nl/handle/1874/445799

Thesis

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Amatngalim, Gimano D; Rodenburg, Lisa W; Aalbers, Bente L et al. · 2022

Full title: Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

DOI: https://dspace.library.uu.nl/handle/1874/446965

Thesis

Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

Rodenburg, Lisa W.; Delpiano, Livia; Railean, Violeta et al. · 2022

Full title: Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

DOI: https://dspace.library.uu.nl/handle/1874/447464

Thesis

Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis

Bracco Gartner, Tom; Crnko, S; Leiteris, Laurynas et al. · 2022

Full title: Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis

DOI: https://dspace.library.uu.nl/handle/1874/445941

Thesis

Advancing lung organoids for COVID-19 research

van der Vaart, Jelte; Lamers, Mart M.; Haagmans, Bart L. et al. · 2021

Full title: Advancing lung organoids for COVID-19 research

Authors: van der Vaart, Jelte; Lamers, Mart M.; Haagmans, Bart L.; Clevers, Hans

DOI: https://dspace.library.uu.nl/handle/1874/445781

Thesis

3D Human iPSC Blood Vessel Organoids as a Source of Flow-Adaptive Vascular Cells for Creating a Human-Relevant 3D-Scaffold Based Macrovessel Model

Meijer, Elana M; Koch, Suzanne E; van Dijk, Christian G M et al. · 2023

Full title: 3D Human iPSC Blood Vessel Organoids as a Source of Flow-Adaptive Vascular Cells for Creating a Human-Relevant 3D-Scaffold Based Macrovessel Model

DOI: https://dspace.library.uu.nl/handle/1874/447383

Thesis

A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use

Ardisasmita, Arif Ibrahim; Schene, Imre F; Joore, Indi P et al. · 2022

Full title: A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use

Authors: Ardisasmita, Arif Ibrahim; Schene, Imre F; Joore, Indi P; Kok, Gautam; Hendriks, Delilah; Artegiani, Benedetta; Mokry, Michal; Nieuwenhuis, Edward E S; Fuchs, Sabine A

DOI: https://dspace.library.uu.nl/handle/1874/447364

Thesis

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Beumer, Joep; Geurts, Maarten H.; Lamers, Mart M. et al. · 2021

Full title: A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

DOI: https://dspace.library.uu.nl/handle/1874/445608

Thesis

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Xu, Xiaoxi; Kumari, Rajendra; Zhou, Jun et al. · 2023

Full title: A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

DOI: https://dspace.library.uu.nl/handle/1874/448336

Thesis

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

Spelier, Sacha; de Poel, Eyleen; Ithakisiou, Georgia N. et al. · 2023

Full title: High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

DOI: https://dspace.library.uu.nl/handle/1874/449840

Thesis

A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology

Nguyen, Vivian V T; Gkouzioti, Vasiliki; Maass, Christian et al. · 2023

Full title: A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology

Authors: Nguyen, Vivian V T; Gkouzioti, Vasiliki; Maass, Christian; Verhaar, Marianne C; Vernooij, Robin W M; van Balkom, Bas W M

DOI: https://dspace.library.uu.nl/handle/1874/449397

Thesis

Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis

Birimberg-Schwartz, Liron; Ip, Wan; Bartlett, Claire et al. · 2023

Full title: Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis

DOI: https://dspace.library.uu.nl/handle/1874/449833

Thesis

A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant

Chiu, Man Chun; Li, Cun; Liu, Xiaojuan et al. · 2022

Full title: A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant

DOI: https://dspace.library.uu.nl/handle/1874/447934

Thesis

Human liver organoids: From generation to applications

Afonso, Marta B; Marques, Vanda; van Mil, Saskia W C et al. · 2024

Full title: Human liver organoids: From generation to applications

Authors: Afonso, Marta B; Marques, Vanda; van Mil, Saskia W C; Rodrigues, Cecilia M P

DOI: https://dspace.library.uu.nl/handle/1874/453554

Thesis

Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine

Langenberg, Karin P.S.; van Hooff, Sander R.; Koopmans, Bianca et al. · 2025

Full title: Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine

DOI: https://dspace.library.uu.nl/handle/1874/460677

Thesis

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Hendriks, Delilah; Brouwers, Jos F.; Hamer, Karien et al. · 2023

Full title: Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

DOI: https://dspace.library.uu.nl/handle/1874/451211

Thesis

Recommendations for robust and reproducible preclinical research in personalised medicine

on behalf of The PERMIT group · 2023

Full title: Recommendations for robust and reproducible preclinical research in personalised medicine

Authors: on behalf of The PERMIT group

DOI: https://dspace.library.uu.nl/handle/1874/455965

Thesis

Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth

Hendriks, Delilah; Artegiani, Benedetta; Margaritis, Thanasis et al. · 2024

Full title: Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth

Authors: Hendriks, Delilah; Artegiani, Benedetta; Margaritis, Thanasis; Zoutendijk, Iris; Chuva de Sousa Lopes, Susana; Clevers, Hans

DOI: https://dspace.library.uu.nl/handle/1874/453266

Thesis

Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options

Boone, Ilja; Houtman, Evelyn; Tuerlings, Margo et al. · 2025

Full title: Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options

Authors: Boone, Ilja; Houtman, Evelyn; Tuerlings, Margo; van den Berg, Jim J.; Lehmann, Johannes; de Keizer, Peter L.J.; Nelissen, Rob G.H.H.; Meulenbelt, Ingrid

DOI: https://dspace.library.uu.nl/handle/1874/460850

Thesis

Species-specific primary cell cultures: a research tool in veterinary science

Sultan, Karim R.; H.P. · 2001

Full title: Species-specific primary cell cultures: a research tool in veterinary science

Authors: Sultan, Karim R.; H.P.

DOI: https://dspace.library.uu.nl/handle/1874/7164

Thesis

Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

Ooft, S. N.; Weeber, F.; Schipper, L. et al. · 2021

Full title: Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

DOI: https://dspace.library.uu.nl/handle/1874/442778

Thesis

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

Brennand, Kristen J.; Marchetto, M. Carol; Benvenisty, Nissim et al. · 2016

Full title: Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

DOI: http://hdl.handle.net/1721.1/100810

Thesis

Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Ardisasmita, Ibrahim; Joore, Indi; Levy, Natacha et al. · 2024

Full title: Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

DOI: https://dspace.library.uu.nl/handle/1874/461147

Thesis

High-throughput identification of small molecules that affect human embryonic vascular development

Vazão, Helena; Rosa, Susana; Barata, Tânia et al. · 2017

Full title: High-throughput identification of small molecules that affect human embryonic vascular development

DOI: http://hdl.handle.net/1721.1/112205

Thesis

A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

Kim, Choong; Kasuya, Junichi; Jeon, Jessie S et al. · 2017

Full title: A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

Authors: Kim, Choong; Kasuya, Junichi; Jeon, Jessie S; Chung, Seok; Kamm, Roger Dale

DOI: http://hdl.handle.net/1721.1/107403

Thesis

Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration

Large, E. M.; Hughes, D. J.; Stokes, C. L. et al. · 2017

Full title: Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration

Authors: Large, E. M.; Hughes, D. J.; Stokes, C. L.; Yu, Jiajie; Cilfone, Nicholas A.; Sarkar, Ujjal; Tannenbaum, Steven R; Lauffenburger, Douglas A; Griffith, Linda G; Cirit, Murat; Wishnok, John S.

DOI: http://hdl.handle.net/1721.1/107165

Thesis

Integration of systems biology with organs-on-chips to humanize therapeutic development

Clark, Amanda M.; Wells, Alan; Edington, Collin D et al. · 2018

Full title: Integration of systems biology with organs-on-chips to humanize therapeutic development

Authors: Clark, Amanda M.; Wells, Alan; Edington, Collin D; Cirit, Murat; Chen, Wen Li; Trumper, David L; Griffith, Linda G

DOI: http://hdl.handle.net/1721.1/115077

Thesis

Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Tardiff, Daniel F.; Lindquist, Susan · 2016

Full title: Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease

Authors: Tardiff, Daniel F.; Lindquist, Susan

DOI: http://hdl.handle.net/1721.1/101272

Thesis

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

Raja, Waseem K; Mungenast, Alison; Lin, Yuan-Ta et al. · 2017

Full title: Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

Authors: Raja, Waseem K; Mungenast, Alison; Lin, Yuan-Ta; Ko, Tak; Abdurrob, Fatema; Seo, Jinsoo; Tsai, Li-Huei

DOI: http://hdl.handle.net/1721.1/106315

Thesis

Colorectal cancer models for novel drug discovery

Golovko, Daniel; Kedrin, Dmitriy; Yilmaz, Omer et al. · 2016

Full title: Colorectal cancer models for novel drug discovery

Authors: Golovko, Daniel; Kedrin, Dmitriy; Yilmaz, Omer; Roper, Jatin

DOI: http://hdl.handle.net/1721.1/105874

Thesis

HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease

Vunjak-Novakovic, Gordana V; Bhatia, Sangeeta N; Chen, Christopher et al. · 2019

Full title: HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease

Authors: Vunjak-Novakovic, Gordana V; Bhatia, Sangeeta N; Chen, Christopher; Hirschi, Karen

DOI: https://hdl.handle.net/1721.1/121236

Thesis

Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification

Logan, David J; Shan, Jing; Bhatia, Sangeeta N et al. · 2017

Full title: Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification

Authors: Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Van Dyk, Anne Carpenter

DOI: http://hdl.handle.net/1721.1/110768

Thesis

Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

Holmberg, Fredrik EO; Seidelin, Jakob B; Tong, Zhixiang et al. · 2018

Full title: Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

Authors: Holmberg, Fredrik EO; Seidelin, Jakob B; Tong, Zhixiang; Li, Yuan; Nielsen, Ole H; Yin, Xiaolei; Mead, Benjamin Elliott; Karp, Jeffrey Michael

DOI: http://hdl.handle.net/1721.1/114033

Thesis

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Zhang, Yu Shrike; Aleman, Julio; Shin, Su Ryon et al. · 2017

Full title: Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

DOI: http://hdl.handle.net/1721.1/112226

Thesis

Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System

Large, Emma; Hughes, David J.; Sarkar, Ujjal et al. · 2017

Full title: Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System

DOI: http://hdl.handle.net/1721.1/110981

Thesis

Liver ‘organ on a chip’

Beckwitt, Colin H.; Clark, Amanda M.; Wheeler, Sarah et al. · 2019

Full title: Liver ‘organ on a chip’

Authors: Beckwitt, Colin H.; Clark, Amanda M.; Wheeler, Sarah; Taylor, D. Lansing; Stolz, Donna B.; Wells, Alan; Griffith, Linda G

DOI: http://hdl.handle.net/1721.1/120832

Thesis

Engineering a perfusable 3D human liver platform from iPS cells

Schepers, Arnout; Li, Cheri Yingjie; Chhabra, Arnav et al. · 2022

Full title: Engineering a perfusable 3D human liver platform from iPS cells

Authors: Schepers, Arnout; Li, Cheri Yingjie; Chhabra, Arnav; Tschudy Seney, Benjamin; Bhatia, Sangeeta N

DOI: https://hdl.handle.net/1721.1/132166.2

Thesis

Maximizing the Impact of Microphysiological Systems with in Vitro–in Vivo Translation

Stokes, Cynthia L.; Cirit, Murat · 2018

Full title: Maximizing the Impact of Microphysiological Systems with in Vitro–in Vivo Translation

Authors: Stokes, Cynthia L.; Cirit, Murat

DOI: http://hdl.handle.net/1721.1/116922

Thesis

Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Bergmann, Sonja; Lawler, Sean E.; Qu, Yuan et al. · 2020

Full title: Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Authors: Bergmann, Sonja; Lawler, Sean E.; Qu, Yuan; Fadzen, Colin M.; Wolfe, Justin; Regan, Michael S.; Pentelute, Bradley L.; Agar, Nathalie Y. R.; Cho, Choi-Fong

DOI: https://hdl.handle.net/1721.1/123679

Thesis

All models are wrong, but some organoids may be useful

Mead, Benjamin Elliott; Karp, Jeffrey Michael · 2019

Full title: All models are wrong, but some organoids may be useful

Authors: Mead, Benjamin Elliott; Karp, Jeffrey Michael

DOI: https://hdl.handle.net/1721.1/122019

Thesis

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

Edington, Collin D; Chen, Wen Li; Geishecker, Emily R et al. · 2018

Full title: Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

DOI: http://hdl.handle.net/1721.1/115178

Thesis

Engineered Livers for Infectious Diseases

Gural, Nil; Mancio Silva, Liliana; He, Jiang et al. · 2021

Full title: Engineered Livers for Infectious Diseases

Authors: Gural, Nil; Mancio Silva, Liliana; He, Jiang; Bhatia, Sangeeta N

DOI: https://hdl.handle.net/1721.1/129529

Thesis

Mathematical modelling to guide experimental protocols for in vitro cell culture

Hyndman, Lauren · 2021

Full title: Mathematical modelling to guide experimental protocols for in vitro cell culture

Authors: Hyndman, Lauren

DOI: https://theses.gla.ac.uk/82510/3/2021HyndmanPhD.pdf

Thesis

Developing physiological 3D in vitro tissue models for rheumatology research

Khan, Aneesah M. · 2022

Full title: Developing physiological 3D in vitro tissue models for rheumatology research

Authors: Khan, Aneesah M.

DOI: https://theses.gla.ac.uk/82838/1/2022KhanAPhD.pdf

Thesis

The utility of multimodal imaging platforms to identify antiviral inhibitors to influenza A virus infection

Orr, Lauren · 2025

Full title: The utility of multimodal imaging platforms to identify antiviral inhibitors to influenza A virus infection

Authors: Orr, Lauren

DOI: https://theses.gla.ac.uk/85335/1/2025OrrPhD.pdf

Thesis

In vitro bronchial mucosa model using air-liquid interface culture on PLLA electrospun membrane

Salah, Nadira Abdi · 2019

Full title: In vitro bronchial mucosa model using air-liquid interface culture on PLLA electrospun membrane

Authors: Salah, Nadira Abdi

DOI: https://theses.gla.ac.uk/75122/3/2018SalahPhD.pdf

Thesis

Development of molecular biology based in vitro toxicology tests fro industrial chemicals

Chen, Renjia · 2004

Full title: Development of molecular biology based in vitro toxicology tests fro industrial chemicals

Authors: Chen, Renjia

DOI: http://hdl.handle.net/1959.4/63371

Thesis

Three-dimensional organoid cell culture models for the study of liver injury

Collins, Scott · 2021

Full title: Three-dimensional organoid cell culture models for the study of liver injury

Authors: Collins, Scott

DOI: http://hdl.handle.net/1959.4/100144

Thesis

Using iPSC models to characterise the role of genetic and environmental effects in variable response to proarrhythmic drugs.

Xu, Michelle · 2024

Full title: Using iPSC models to characterise the role of genetic and environmental effects in variable response to proarrhythmic drugs.

Authors: Xu, Michelle

DOI: http://hdl.handle.net/1959.4/102302

Thesis

Molecular and Computational Platforms for Cancer Drug Screening and Precision Therapy

Matthews, Jonathan Martin · 2023

Full title: Molecular and Computational Platforms for Cancer Drug Screening and Precision Therapy

Authors: Matthews, Jonathan Martin

DOI: https://knowledge.uchicago.edu/record/6529/files/Matthews_uchicago_0330D_16945.pdf

Thesis

A 3D in vitro model of the human gut-microbiome. A bioelectronics approach.

Moysidou, Chrysanthi-Maria · 2021

Full title: A 3D in vitro model of the human gut-microbiome. A bioelectronics approach.

Authors: Moysidou, Chrysanthi-Maria

DOI: https://www.repository.cam.ac.uk/handle/1810/327423

Thesis

Aortic “Disease-in-a-Dish”: Mechanistic Insights and Drug Development Using iPSC-Based Disease Modeling

Davaapil, Hongorzul; Shetty, Deeti K.; Sinha, Sanjay · 2020

Full title: Aortic “Disease-in-a-Dish”: Mechanistic Insights and Drug Development Using iPSC-Based Disease Modeling

Authors: Davaapil, Hongorzul; Shetty, Deeti K.; Sinha, Sanjay

DOI: https://www.repository.cam.ac.uk/handle/1810/312759

Thesis

In vitro models for investigating itch

Smith, Ewan; Mießner, Hendrik; Judith, Seidel · 2022

Full title: In vitro models for investigating itch

Authors: Smith, Ewan; Mießner, Hendrik; Judith, Seidel

DOI: https://www.repository.cam.ac.uk/handle/1810/341948

Thesis

Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis

Orbach, Sophia Michelle · 2019

Full title: Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis

Authors: Orbach, Sophia Michelle

DOI: http://hdl.handle.net/10919/93313

Thesis

Developing bioelectronic sensors for 3D in vitro models at the air liquid interface: Innovative technology for biomedical and respiratory research.

Barron, Sarah · 2024

Full title: Developing bioelectronic sensors for 3D in vitro models at the air liquid interface: Innovative technology for biomedical and respiratory research.

Authors: Barron, Sarah

DOI: https://www.repository.cam.ac.uk/handle/1810/363508

Thesis

Human Liver Organoids as models for investigating drug-induced liver injury

Kaluthantrige Don, Mewanthi Flaminia · 2022

Full title: Human Liver Organoids as models for investigating drug-induced liver injury

Authors: Kaluthantrige Don, Mewanthi Flaminia

DOI: https://www.repository.cam.ac.uk/handle/1810/335284

Thesis

Development and Characterisation of a Vessel-On-a-Chip Model of Inflammation and Inflammatory Haemostasis

Riddle, Rebecca · 2023

Full title: Development and Characterisation of a Vessel-On-a-Chip Model of Inflammation and Inflammatory Haemostasis

Authors: Riddle, Rebecca

DOI: https://www.repository.cam.ac.uk/handle/1810/361577

Thesis

3D Cell Culture in Microgels: A Novel Screening Platform for Disease Modelling and Drug Testing

Maring, Alisa · 2025

Full title: 3D Cell Culture in Microgels: A Novel Screening Platform for Disease Modelling and Drug Testing

Authors: Maring, Alisa

DOI: https://www.repository.cam.ac.uk/handle/1810/388923

Thesis

hiPSC-Derived Cerebral Small Vessel Disease Models

Al-Thani, Maha · 2024

Full title: hiPSC-Derived Cerebral Small Vessel Disease Models

Authors: Al-Thani, Maha

DOI: https://www.repository.cam.ac.uk/handle/1810/366502

Thesis

Three-Dimensional Cell Cultures as a Research Platform in Lung Diseases and COVID-19

Ribeiro-Paes, João Tadeu · 2021

Full title: Three-Dimensional Cell Cultures as a Research Platform in Lung Diseases and COVID-19

Authors: Ribeiro-Paes, João Tadeu

DOI: https://doi.org/10.1007/s13770-021-00348-x

Thesis

Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19

Pereira, Lygia da Veiga · 2020

Full title: Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19

Authors: Pereira, Lygia da Veiga

DOI: https://doi.org/10.1590/1678-4685-gmb-2020-0198

Thesis

Optimizing in Vitro Motility Assays for High-Throughput Analysis of Actin-Myosin Dynamics and Drug Screening

Presley, Noah · 2025

Full title: Optimizing in Vitro Motility Assays for High-Throughput Analysis of Actin-Myosin Dynamics and Drug Screening

Authors: Presley, Noah

DOI: https://hdl.handle.net/10214/29358

Thesis

High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

Leuchowius, Karl-Johan · 2010

Full title: High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

Authors: Leuchowius, Karl-Johan

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119530

Thesis

Visualization of Protein Activity Status in situ Using Proximity Ligation Assays

Jarvius, Malin · 2010

Full title: Visualization of Protein Activity Status in situ Using Proximity Ligation Assays

Authors: Jarvius, Malin

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131934

Thesis

High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities

Senkowski, Wojciech · 2017

Full title: High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities

Authors: Senkowski, Wojciech

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-320598

Thesis

Molecular Approaches to Explore Drug-Target Interactions

Al-Amin, Abdullah · 2019

Full title: Molecular Approaches to Explore Drug-Target Interactions

Authors: Al-Amin, Abdullah

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-374329

Thesis

Development of Human Pancreatic Ductal Epithelial Cells as a model of Cystic Fibrosis Pancreatic Disease

Malik, Sarah · 2024

Full title: Development of Human Pancreatic Ductal Epithelial Cells as a model of Cystic Fibrosis Pancreatic Disease

Authors: Malik, Sarah

DOI: https://hdl.handle.net/1773/52146

Thesis

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier

Jelinsky, Scott A; Derksen, Merel; Bauman, Eric et al. · 2023

Full title: Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier

DOI: https://dspace.library.uu.nl/handle/1874/447481

Thesis

Narrowing the translational gap in metabolic dysfunction-associated steatotic liver disease (MASLD) drug development

Aurino Kemas (18658303) · 2025

Full title: Narrowing the translational gap in metabolic dysfunction-associated steatotic liver disease (MASLD) drug development

Authors: Aurino Kemas (18658303)

DOI: oai:figshare.com:article/29921738

Thesis

An evaluation of in vitro models for the assessment of mitochondrial toxicity within Drug Induced Liver Injury (DILI)

Douglas, O · 2017

Full title: An evaluation of in vitro models for the assessment of mitochondrial toxicity within Drug Induced Liver Injury (DILI)

Authors: Douglas, O

DOI: https://livrepository.liverpool.ac.uk/3012327/1/200916787_Mar2017.pdf

Thesis

Development and Exploration of New Automated Tools to Accelerate Research on Tissue and Tumor Model Systems

Schuster, Brooke Elizabeth · 2022

Full title: Development and Exploration of New Automated Tools to Accelerate Research on Tissue and Tumor Model Systems

Authors: Schuster, Brooke Elizabeth

DOI: https://knowledge.uchicago.edu/record/3653/files/Schuster_uchicago_0330D_16165.pdf

Thesis

Liver organoids: from basic research to therapeutic applications.

Prior, Nicole; Inacio, Patricia; Huch, Meritxell · 2019

Full title: Liver organoids: from basic research to therapeutic applications.

Authors: Prior, Nicole; Inacio, Patricia; Huch, Meritxell

DOI: https://www.repository.cam.ac.uk/handle/1810/294664

Patent

us-2023304996-a1

· 2023

Full title: us-2023304996-a1

Patent

us-2023356216-a1

· 2023

Full title: us-2023356216-a1

Patent

us-2023374446-a1

· 2023

Full title: us-2023374446-a1

Patent

us-2023383264-a1

· 2023

Full title: us-2023383264-a1

Patent

us-2023368374-a1

· 2023

Full title: us-2023368374-a1

Patent

us-2023364528-a1

· 2023

Full title: us-2023364528-a1

Patent

us-2024010961-a1

· 2024

Full title: us-2024010961-a1

Patent

us-2024010987-a1

· 2024

Full title: us-2024010987-a1

Patent

us-2024026268-a1

· 2024

Full title: us-2024026268-a1

Patent

us-2024010993-a1

· 2024

Full title: us-2024010993-a1

Patent

us-2024011973-a1

· 2024

Full title: us-2024011973-a1

Patent

us-2024024873-a1

· 2024

Full title: us-2024024873-a1

Patent

us-2024036033-a1

· 2024

Full title: us-2024036033-a1

Patent

us-2024065237-a1

· 2024

Full title: us-2024065237-a1

Patent

us-2024117431-a1

· 2024

Full title: us-2024117431-a1

Patent

us-2024043808-a1

· 2024

Full title: us-2024043808-a1

Patent

us-2024032528-a1

· 2024

Full title: us-2024032528-a1

Patent

us-2024117320-a1

· 2024

Full title: us-2024117320-a1

Patent

us-2024093136-a1

· 2024

Full title: us-2024093136-a1

Patent

us-2024182863-a1

· 2024

Full title: us-2024182863-a1

Patent

us-2024093154-a1

· 2024

Full title: us-2024093154-a1

Patent

us-2024133872-a1

· 2024

Full title: us-2024133872-a1

Patent

us-2024093236-a1

· 2024

Full title: us-2024093236-a1

Patent

us-2024076593-a1

· 2024

Full title: us-2024076593-a1

Patent

us-2024115620-a1

· 2024

Full title: us-2024115620-a1

Patent

us-2024125767-a1

· 2024

Full title: us-2024125767-a1

Patent

us-2024099278-a1

· 2024

Full title: us-2024099278-a1

Patent

us-2024228927-a1

· 2024

Full title: us-2024228927-a1

Patent

us-2024133873-a1

· 2024

Full title: us-2024133873-a1

Patent

us-2024132849-a1

· 2024

Full title: us-2024132849-a1

Patent

us-2024198337-a1

· 2024

Full title: us-2024198337-a1

Patent

us-2024183843-a1

· 2024

Full title: us-2024183843-a1

Patent

us-2024118267-a1

· 2024

Full title: us-2024118267-a1

Patent

us-2024142438-a1

· 2024

Full title: us-2024142438-a1

Patent

us-2024158728-a1

· 2024

Full title: us-2024158728-a1

Patent

us-2024254449-a1

· 2024

Full title: us-2024254449-a1

Patent

us-2024271066-a1

· 2024

Full title: us-2024271066-a1

Patent

us-2024182868-a1

· 2024

Full title: us-2024182868-a1

Patent

us-2024301358-a1

· 2024

Full title: us-2024301358-a1

Patent

us-2024210384-a1

· 2024

Full title: us-2024210384-a1

Patent

us-2024218321-a1

· 2024

Full title: us-2024218321-a1

Patent

us-2024228929-a1

· 2024

Full title: us-2024228929-a1

Patent

us-2024228973-a9

· 2024

Full title: us-2024228973-a9

Patent

us-2024360400-a1

· 2024

Full title: us-2024360400-a1

Patent

us-2024302352-a1

· 2024

Full title: us-2024302352-a1

Patent

us-2024368556-a1

· 2024

Full title: us-2024368556-a1

Patent

us-2024230629-a9

· 2024

Full title: us-2024230629-a9

Patent

us-2024309331-a1

· 2024

Full title: us-2024309331-a1

Patent

us-2024392249-a1

· 2024

Full title: us-2024392249-a1

Patent

us-2024307591-a1

· 2024

Full title: us-2024307591-a1

Patent

us-2024320992-a1

· 2024

Full title: us-2024320992-a1

Patent

us-2024400997-a1

· 2024

Full title: us-2024400997-a1

Patent

us-2025017977-a1

· 2025

Full title: us-2025017977-a1

Patent

us-2025002862-a1

· 2025

Full title: us-2025002862-a1

Patent

us-2025084356-a1

· 2025

Full title: us-2025084356-a1

Patent

us-2025066736-a1

· 2025

Full title: us-2025066736-a1

Patent

us-2024392223-a1

· 2024

Full title: us-2024392223-a1

Patent

us-2024417661-a1

· 2024

Full title: us-2024417661-a1

Patent

us-2025067728-a1

· 2025

Full title: us-2025067728-a1

Patent

us-2025064051-a1

· 2025

Full title: us-2025064051-a1

Patent

us-2025051732-a1

· 2025

Full title: us-2025051732-a1

Patent

us-2025164464-a1

· 2025

Full title: us-2025164464-a1

Patent

us-2025129338-a1

· 2025

Full title: us-2025129338-a1

Patent

us-2025172543-a1

· 2025

Full title: us-2025172543-a1

Patent

us-2025120372-a1

· 2025

Full title: us-2025120372-a1

Patent

us-2025057128-a1

· 2025

Full title: us-2025057128-a1

Patent

us-2025066703-a1

· 2025

Full title: us-2025066703-a1

Patent

us-2025228899-a1

· 2025

Full title: us-2025228899-a1

Patent

us-2025207101-a1

· 2025

Full title: us-2025207101-a1

Patent

us-2025248377-a1

· 2025

Full title: us-2025248377-a1

Patent

us-2025235802-a1

· 2025

Full title: us-2025235802-a1

Patent

us-2025136910-a1

· 2025

Full title: us-2025136910-a1

Patent

us-2025179436-a1

· 2025

Full title: us-2025179436-a1

Patent

us-2025145962-a1

· 2025

Full title: us-2025145962-a1

Patent

us-2025257325-a1

· 2025

Full title: us-2025257325-a1

Patent

us-2025230390-a1

· 2025

Full title: us-2025230390-a1

Patent

us-2025250521-a1

· 2025

Full title: us-2025250521-a1

Patent

us-2025304896-a1

· 2025

Full title: us-2025304896-a1

Patent

us-2025297225-a1

· 2025

Full title: us-2025297225-a1

Patent

us-2025304912-a1

· 2025

Full title: us-2025304912-a1

Patent

us-2025304893-a1

· 2025

Full title: us-2025304893-a1

Patent

us-2025222453-a1

· 2025

Full title: us-2025222453-a1

Patent

us-2025212854-a1

· 2025

Full title: us-2025212854-a1

Patent

us-5565353-a

· 1996

Full title: us-5565353-a

Patent

us-5270192-a

· 1993

Full title: us-5270192-a

Patent

us-2025313807-a1

· 2025

Full title: us-2025313807-a1

Patent

us-10030219-b2

· 2018

Full title: us-10030219-b2

Patent

us-10087422-b2

· 2018

Full title: us-10087422-b2

Patent

us-10087408-b2

· 2018

Full title: us-10087408-b2

Patent

us-10184113-b2

· 2019

Full title: us-10184113-b2

Patent

us-10184102-b2

· 2019

Full title: us-10184102-b2

Patent

us-10254274-b2

· 2019

Full title: us-10254274-b2

Patent

us-10392595-b2

· 2019

Full title: us-10392595-b2

Patent

us-10184109-b2

· 2019

Full title: us-10184109-b2

Patent

us-10473646-b2

· 2019

Full title: us-10473646-b2

Patent

us-10233416-b2

· 2019

Full title: us-10233416-b2

Patent

us-10266806-b2

· 2019

Full title: us-10266806-b2

Patent

us-10273441-b2

· 2019

Full title: us-10273441-b2

Patent

us-10314295-b2

· 2019

Full title: us-10314295-b2

Patent

us-10213525-b2

· 2019

Full title: us-10213525-b2

Patent

us-10336987-b2

· 2019

Full title: us-10336987-b2

Patent

us-10696949-b2

· 2020

Full title: us-10696949-b2

Patent

us-10488390-b2

· 2019

Full title: us-10488390-b2

Patent

us-10421936-b2

· 2019

Full title: us-10421936-b2

Patent

us-10317395-b1

· 2019

Full title: us-10317395-b1

Patent

us-10519410-b2

· 2019

Full title: us-10519410-b2

Patent

us-10689608-b2

· 2020

Full title: us-10689608-b2

Patent

us-10465155-b2

· 2019

Full title: us-10465155-b2

Patent

us-10954489-b2

· 2021

Full title: us-10954489-b2

Patent

us-10632305-b2

· 2020

Full title: us-10632305-b2

Patent

us-10704018-b2

· 2020

Full title: us-10704018-b2

Patent

us-10683483-b2

· 2020

Full title: us-10683483-b2

Patent

us-10526578-b2

· 2020

Full title: us-10526578-b2

Patent

us-10597623-b2

· 2020

Full title: us-10597623-b2

Patent

us-10828638-b2

· 2020

Full title: us-10828638-b2

Patent

us-10976308-b2

· 2021

Full title: us-10976308-b2

Patent

us-10815460-b2

· 2020

Full title: us-10815460-b2

Patent

us-10785968-b2

· 2020

Full title: us-10785968-b2

Patent

us-10767164-b2

· 2020

Full title: us-10767164-b2

Patent

us-10732174-b2

· 2020

Full title: us-10732174-b2

Patent

us-10738270-b2

· 2020

Full title: us-10738270-b2

Patent

us-10913924-b2

· 2021

Full title: us-10913924-b2

Patent

us-11001795-b2

· 2021

Full title: us-11001795-b2

Patent

us-10988721-b2

· 2021

Full title: us-10988721-b2

Patent

us-10869465-b2

· 2020

Full title: us-10869465-b2

Patent

us-10988722-b2

· 2021

Full title: us-10988722-b2

Patent

us-10018620-b2

· 2018

Full title: us-10018620-b2

Patent

us-11124774-b2

· 2021

Full title: us-11124774-b2

Patent

us-11142734-b2

· 2021

Full title: us-11142734-b2

Patent

us-11041145-b2

· 2021

Full title: us-11041145-b2

Patent

us-11059041-b2

· 2021

Full title: us-11059041-b2

Patent

us-11072772-b2

· 2021

Full title: us-11072772-b2

Patent

us-2016053231-a1

· 2016

Full title: us-2016053231-a1

Patent

us-2016083681-a1

· 2016

Full title: us-2016083681-a1

Patent

us-2015344828-a1

· 2015

Full title: us-2015344828-a1

Patent

us-2016017288-a1

· 2016

Full title: us-2016017288-a1

Patent

us-2015283269-a1

· 2015

Full title: us-2015283269-a1

Patent

us-2016137986-a1

· 2016

Full title: us-2016137986-a1

Patent

us-2016272946-a1

· 2016

Full title: us-2016272946-a1

Patent

us-2016131636-a1

· 2016

Full title: us-2016131636-a1

Patent

us-2015301027-a1

· 2015

Full title: us-2015301027-a1

Patent

us-2016130551-a1

· 2016

Full title: us-2016130551-a1

Patent

us-2015282460-a1

· 2015

Full title: us-2015282460-a1

Patent

us-2016339429-a1

· 2016

Full title: us-2016339429-a1

Patent

us-2016298087-a1

· 2016

Full title: us-2016298087-a1

Patent

us-2016340632-a1

· 2016

Full title: us-2016340632-a1

Patent

us-2016145570-a1

· 2016

Full title: us-2016145570-a1

Patent

us-2016348067-a1

· 2016

Full title: us-2016348067-a1

Patent

us-2017055522-a1

· 2017

Full title: us-2017055522-a1

Patent

us-2016363584-a1

· 2016

Full title: us-2016363584-a1

Patent

us-2017009194-a1

· 2017

Full title: us-2017009194-a1

Patent

us-2016366862-a1

· 2016

Full title: us-2016366862-a1

Patent

us-2017055504-a1

· 2017

Full title: us-2017055504-a1

Patent

us-2016130543-a1

· 2016

Full title: us-2016130543-a1

Patent

us-2017158997-a1

· 2017

Full title: us-2017158997-a1

Patent

us-2017145386-a1

· 2017

Full title: us-2017145386-a1

Patent

us-2017211029-a1

· 2017

Full title: us-2017211029-a1

Patent

us-2018015126-a1

· 2018

Full title: us-2018015126-a1

Patent

us-2017290665-a1

· 2017

Full title: us-2017290665-a1

Patent

us-2017370908-a1

· 2017

Full title: us-2017370908-a1

Patent

us-2017058257-a1

· 2017

Full title: us-2017058257-a1

Patent

us-2017269066-a1

· 2017

Full title: us-2017269066-a1

Patent

us-2017058248-a1

· 2017

Full title: us-2017058248-a1

Patent

us-2018042970-a1

· 2018

Full title: us-2018042970-a1

Patent

us-2018024121-a1

· 2018

Full title: us-2018024121-a1

Patent

us-2018064527-a1

· 2018

Full title: us-2018064527-a1

Patent

us-2017198254-a1

· 2017

Full title: us-2017198254-a1

Patent

us-2018049413-a1

· 2018

Full title: us-2018049413-a1

Patent

us-2018163166-a1

· 2018

Full title: us-2018163166-a1

Patent

us-2018147242-a1

· 2018

Full title: us-2018147242-a1

Patent

us-2018185844-a1

· 2018

Full title: us-2018185844-a1

Patent

us-2018216063-a1

· 2018

Full title: us-2018216063-a1

Patent

us-2018172668-a1

· 2018

Full title: us-2018172668-a1

Patent

us-2018223253-a1

· 2018

Full title: us-2018223253-a1

Patent

us-2018135011-a1

· 2018

Full title: us-2018135011-a1

Patent

us-2018224432-a1

· 2018

Full title: us-2018224432-a1

Patent

us-2018230417-a1

· 2018

Full title: us-2018230417-a1

Patent

us-2018280971-a1

· 2018

Full title: us-2018280971-a1

Patent

us-2018237861-a1

· 2018

Full title: us-2018237861-a1

Patent

us-2018291350-a1

· 2018

Full title: us-2018291350-a1

Patent

us-2018305669-a1

· 2018

Full title: us-2018305669-a1

Patent

us-2018355298-a1

· 2018

Full title: us-2018355298-a1

Patent

us-2018321224-a1

· 2018

Full title: us-2018321224-a1

Patent

us-2018282699-a1

· 2018

Full title: us-2018282699-a1

Patent

us-2018334646-a1

· 2018

Full title: us-2018334646-a1

Patent

us-2019048315-a1

· 2019

Full title: us-2019048315-a1

Patent

us-2019018002-a1

· 2019

Full title: us-2019018002-a1

Patent

us-2018245050-a1

· 2018

Full title: us-2018245050-a1

Patent

us-2019031992-a1

· 2019

Full title: us-2019031992-a1

Patent

us-2018369423-a1

· 2018

Full title: us-2018369423-a1

Patent

us-2019119619-a1

· 2019

Full title: us-2019119619-a1

Patent

us-2019032021-a1

· 2019

Full title: us-2019032021-a1

Patent

us-2019040349-a1

· 2019

Full title: us-2019040349-a1

Patent

us-2018327701-a1

· 2018

Full title: us-2018327701-a1

Patent

us-2018327702-a1

· 2018

Full title: us-2018327702-a1

Patent

us-2019062684-a1

· 2019

Full title: us-2019062684-a1

Patent

us-2019119626-a1

· 2019

Full title: us-2019119626-a1

Patent

us-2019093077-a1

· 2019

Full title: us-2019093077-a1

Patent

us-2019071638-a1

· 2019

Full title: us-2019071638-a1

Patent

us-2019119647-a1

· 2019

Full title: us-2019119647-a1

Patent

us-2019218540-a1

· 2019

Full title: us-2019218540-a1

Patent

us-2019112566-a1

· 2019

Full title: us-2019112566-a1

Patent

us-2019216062-a1

· 2019

Full title: us-2019216062-a1

Patent

us-2019076842-a1

· 2019

Full title: us-2019076842-a1

Patent

us-2019218588-a1

· 2019

Full title: us-2019218588-a1

Patent

us-2019232277-a1

· 2019

Full title: us-2019232277-a1

Patent

us-2019249215-a1

· 2019

Full title: us-2019249215-a1

Patent

us-2019153395-a1

· 2019

Full title: us-2019153395-a1

Patent

us-2019177678-a1

· 2019

Full title: us-2019177678-a1

Patent

us-2019169557-a1

· 2019

Full title: us-2019169557-a1

Patent

us-2019233787-a1

· 2019

Full title: us-2019233787-a1

Patent

us-2019284535-a1

· 2019

Full title: us-2019284535-a1

Patent

us-2019300851-a1

· 2019

Full title: us-2019300851-a1

Patent

us-2019330583-a1

· 2019

Full title: us-2019330583-a1

Patent

us-2019339257-a1

· 2019

Full title: us-2019339257-a1

Patent

us-2019285619-a1

· 2019

Full title: us-2019285619-a1

Patent

us-2019292518-a1

· 2019

Full title: us-2019292518-a1

Patent

us-2019289834-a1

· 2019

Full title: us-2019289834-a1

Patent

us-2019276799-a1

· 2019

Full title: us-2019276799-a1

Patent

us-2019331662-a1

· 2019

Full title: us-2019331662-a1

Patent

us-2019298775-a1

· 2019

Full title: us-2019298775-a1

Patent

us-2019316093-a1

· 2019

Full title: us-2019316093-a1

Patent

us-2019365951-a1

· 2019

Full title: us-2019365951-a1

Patent

us-2020010806-a1

· 2020

Full title: us-2020010806-a1

Patent

us-2020015462-a1

· 2020

Full title: us-2020015462-a1

Patent

us-2019320629-a1

· 2019

Full title: us-2019320629-a1

Patent

us-2019376013-a1

· 2019

Full title: us-2019376013-a1

Patent

us-2019382701-a1

· 2019

Full title: us-2019382701-a1

Patent

us-2020132670-a1

· 2020

Full title: us-2020132670-a1

Patent

us-2020017811-a1

· 2020

Full title: us-2020017811-a1

Patent

us-2019367860-a1

· 2019

Full title: us-2019367860-a1

Patent

us-2020048601-a1

· 2020

Full title: us-2020048601-a1

Patent

us-2020018747-a1

· 2020

Full title: us-2020018747-a1

Patent

us-2020115682-a1

· 2020

Full title: us-2020115682-a1

Patent

us-2020071674-a1

· 2020

Full title: us-2020071674-a1

Patent

us-2020190455-a1

· 2020

Full title: us-2020190455-a1

Patent

us-2020140801-a1

· 2020

Full title: us-2020140801-a1

Patent

us-2020121464-a1

· 2020

Full title: us-2020121464-a1

Patent

us-2020181580-a1

· 2020

Full title: us-2020181580-a1

Patent

us-2020095525-a1

· 2020

Full title: us-2020095525-a1

Patent

us-2020063081-a1

· 2020

Full title: us-2020063081-a1

Patent

us-2020188444-a1

· 2020

Full title: us-2020188444-a1

Patent

us-2020239843-a1

· 2020

Full title: us-2020239843-a1

Patent

us-2020140808-a1

· 2020

Full title: us-2020140808-a1

Patent

us-2020224136-a1

· 2020

Full title: us-2020224136-a1

Patent

us-2020190456-a1

· 2020

Full title: us-2020190456-a1

Patent

us-2020208090-a1

· 2020

Full title: us-2020208090-a1

Patent

us-2020224171-a1

· 2020

Full title: us-2020224171-a1

Patent

us-2020325431-a1

· 2020

Full title: us-2020325431-a1

Patent

us-2020283732-a1

· 2020

Full title: us-2020283732-a1

Patent

us-2020277568-a1

· 2020

Full title: us-2020277568-a1

Patent

us-2020239851-a1

· 2020

Full title: us-2020239851-a1

Patent

us-2020216791-a1

· 2020

Full title: us-2020216791-a1

Patent

us-2020339956-a1

· 2020

Full title: us-2020339956-a1

Patent

us-2020199537-a1

· 2020

Full title: us-2020199537-a1

Patent

us-2020115680-a1

· 2020

Full title: us-2020115680-a1

Patent

us-2020354663-a1

· 2020

Full title: us-2020354663-a1

Patent

us-2020270582-a1

· 2020

Full title: us-2020270582-a1

Patent

us-2020377860-a1

· 2020

Full title: us-2020377860-a1

Patent

us-2020339955-a1

· 2020

Full title: us-2020339955-a1

Patent

us-2020369996-a1

· 2020

Full title: us-2020369996-a1

Patent

us-2021018492-a1

· 2021

Full title: us-2021018492-a1

Patent

us-2020385661-a1

· 2020

Full title: us-2020385661-a1

Patent

us-2020390825-a1

· 2020

Full title: us-2020390825-a1

Patent

us-2020370005-a1

· 2020

Full title: us-2020370005-a1

Patent

us-2020352918-a1

· 2020

Full title: us-2020352918-a1

Patent

us-2020378952-a1

· 2020

Full title: us-2020378952-a1

Patent

us-2020378956-a1

· 2020

Full title: us-2020378956-a1

Patent

us-2020377863-a1

· 2020

Full title: us-2020377863-a1

Patent

us-2021040428-a1

· 2021

Full title: us-2021040428-a1

Patent

us-2021047617-a1

· 2021

Full title: us-2021047617-a1

Patent

us-2021095256-a1

· 2021

Full title: us-2021095256-a1

Patent

us-2020399611-a1

· 2020

Full title: us-2020399611-a1

Patent

us-2021054321-a1

· 2021

Full title: us-2021054321-a1

Patent

us-2021100228-a1

· 2021

Full title: us-2021100228-a1

Patent

us-2021031197-a1

· 2021

Full title: us-2021031197-a1

Patent

us-2021062129-a1

· 2021

Full title: us-2021062129-a1

Patent

us-2021055283-a1

· 2021

Full title: us-2021055283-a1

Patent

us-2021179992-a1

· 2021

Full title: us-2021179992-a1

Patent

us-2021054324-a1

· 2021

Full title: us-2021054324-a1

Patent

us-2021108178-a1

· 2021

Full title: us-2021108178-a1

Patent

us-2021130774-a1

· 2021

Full title: us-2021130774-a1

Patent

us-2021189346-a1

· 2021

Full title: us-2021189346-a1

Patent

us-2021127647-a1

· 2021

Full title: us-2021127647-a1

Patent

us-2021115406-a1

· 2021

Full title: us-2021115406-a1

Patent

us-2021260137-a1

· 2021

Full title: us-2021260137-a1

Patent

us-2021269774-a1

· 2021

Full title: us-2021269774-a1

Patent

us-2021254012-a1

· 2021

Full title: us-2021254012-a1

Patent

us-2021222131-a1

· 2021

Full title: us-2021222131-a1

Patent

us-2021322642-a1

· 2021

Full title: us-2021322642-a1

Patent

us-2021292714-a1

· 2021

Full title: us-2021292714-a1

Patent

us-2021171889-a1

· 2021

Full title: us-2021171889-a1

Patent

us-2021229097-a1

· 2021

Full title: us-2021229097-a1

Patent

us-2021277349-a1

· 2021

Full title: us-2021277349-a1

Patent

us-2021252509-a1

· 2021

Full title: us-2021252509-a1

Patent

us-2021341462-a1

· 2021

Full title: us-2021341462-a1

Patent

us-5491284-a

· 1996

Full title: us-5491284-a

Patent

us-5112757-a

· 1992

Full title: us-5112757-a

Patent

us-6008047-a

· 1999

Full title: us-6008047-a

Patent

us-2024158755-a1

· 2024

Full title: us-2024158755-a1

Patent

us-6228595-b1

· 2001

Full title: us-6228595-b1

Patent

us-5849995-a

· 1998

Full title: us-5849995-a

Patent

us-6284239-b1

· 2001

Full title: us-6284239-b1

Patent

us-5625128-a

· 1997

Full title: us-5625128-a

Patent

us-5986170-a

· 1999

Full title: us-5986170-a

Patent

us-5667766-a

· 1997

Full title: us-5667766-a

Patent

us-6780580-b2

· 2004

Full title: us-6780580-b2

Patent

us-6197575-b1

· 2001

Full title: us-6197575-b1

Patent

us-7622298-b2

· 2009

Full title: us-7622298-b2

Patent

us-6759245-b1

· 2004

Full title: us-6759245-b1

Patent

us-6949691-b2

· 2005

Full title: us-6949691-b2

Patent

us-7745120-b2

· 2010

Full title: us-7745120-b2

Patent

us-7470424-b2

· 2008

Full title: us-7470424-b2

Patent

us-7659441-b2

· 2010

Full title: us-7659441-b2

Patent

us-7691369-b2

· 2010

Full title: us-7691369-b2

Patent

us-7468264-b2

· 2008

Full title: us-7468264-b2

Patent

us-7604934-b2

· 2009

Full title: us-7604934-b2

Patent

us-7449306-b2

· 2008

Full title: us-7449306-b2

Patent

us-8241905-b2

· 2012

Full title: us-8241905-b2

Patent

us-7763456-b2

· 2010

Full title: us-7763456-b2

Patent

us-7682781-b2

· 2010

Full title: us-7682781-b2

Patent

us-8318479-b2

· 2012

Full title: us-8318479-b2

Patent

us-8012456-b2

· 2011

Full title: us-8012456-b2

Patent

us-8481303-b2

· 2013

Full title: us-8481303-b2

Patent

us-8747776-b2

· 2014

Full title: us-8747776-b2

Patent

us-8071381-b2

· 2011

Full title: us-8071381-b2

Patent

us-7393994-b2

· 2008

Full title: us-7393994-b2

Patent

us-9068281-b2

· 2015

Full title: us-9068281-b2

Patent

us-9090878-b2

· 2015

Full title: us-9090878-b2

Patent

us-9097702-b2

· 2015

Full title: us-9097702-b2

Patent

us-9029627-b2

· 2015

Full title: us-9029627-b2

Patent

us-9442105-b2

· 2016

Full title: us-9442105-b2

Patent

us-9267938-b2

· 2016

Full title: us-9267938-b2

Patent

us-9687348-b2

· 2017

Full title: us-9687348-b2

Patent

us-8771930-b2

· 2014

Full title: us-8771930-b2

Patent

us-9700024-b2

· 2017

Full title: us-9700024-b2

Patent

us-9610578-b2

· 2017

Full title: us-9610578-b2

Patent

us-8679843-b2

· 2014

Full title: us-8679843-b2

Patent

us-9506037-b2

· 2016

Full title: us-9506037-b2

Patent

us-9695399-b2

· 2017

Full title: us-9695399-b2

Patent

us-9810685-b2

· 2017

Full title: us-9810685-b2

Patent

us-9732316-b2

· 2017

Full title: us-9732316-b2

Patent

us-9506024-b2

· 2016

Full title: us-9506024-b2

Patent

us-9464271-b2

· 2016

Full title: us-9464271-b2

Patent

us-9217156-b2

· 2015

Full title: us-9217156-b2

Patent

us-9777258-b2

· 2017

Full title: us-9777258-b2

Patent

us-9743646-b2

· 2017

Full title: us-9743646-b2

Patent

us-9986724-b2

· 2018

Full title: us-9986724-b2

Patent

us-9901082-b2

· 2018

Full title: us-9901082-b2

Patent

us-9969979-b2

· 2018

Full title: us-9969979-b2

Patent

us-9752116-b2

· 2017

Full title: us-9752116-b2

Patent

us-2021395700-a1

· 2021

Full title: us-2021395700-a1

Patent

us-2022042975-a1

· 2022

Full title: us-2022042975-a1

Patent

us-2021371783-a1

· 2021

Full title: us-2021371783-a1

Patent

us-2021301238-a1

· 2021

Full title: us-2021301238-a1

Patent

us-2022081663-a1

· 2022

Full title: us-2022081663-a1

Patent

us-2021371792-a1

· 2021

Full title: us-2021371792-a1

Patent

us-2022081659-a1

· 2022

Full title: us-2022081659-a1

Patent

us-2022010282-a1

· 2022

Full title: us-2022010282-a1

Patent

us-2022072203-a1

· 2022

Full title: us-2022072203-a1

Patent

us-2022002655-a1

· 2022

Full title: us-2022002655-a1

Patent

us-2022056419-a1

· 2022

Full title: us-2022056419-a1

Patent

us-2022010252-a1

· 2022

Full title: us-2022010252-a1

Patent

us-2022016178-a1

· 2022

Full title: us-2022016178-a1

Patent

us-2022062791-a1

· 2022

Full title: us-2022062791-a1

Patent

us-2022042976-a1

· 2022

Full title: us-2022042976-a1

Patent

us-2021372995-a1

· 2021

Full title: us-2021372995-a1

Patent

us-2022074924-a1

· 2022

Full title: us-2022074924-a1

Patent

us-2022118446-a1

· 2022

Full title: us-2022118446-a1

Patent

us-2022010255-a1

· 2022

Full title: us-2022010255-a1

Patent

us-2022145259-a1

· 2022

Full title: us-2022145259-a1

Patent

us-2022177833-a1

· 2022

Full title: us-2022177833-a1

Patent

us-2022106547-a1

· 2022

Full title: us-2022106547-a1

Patent

us-2022130280-a1

· 2022

Full title: us-2022130280-a1

Patent

us-2022087233-a1

· 2022

Full title: us-2022087233-a1

Patent

us-2022229045-a1

· 2022

Full title: us-2022229045-a1

Patent

us-2022163511-a1

· 2022

Full title: us-2022163511-a1

Patent

us-2022238042-a1

· 2022

Full title: us-2022238042-a1

Patent

us-2022135941-a1

· 2022

Full title: us-2022135941-a1

Patent

us-2022145265-a1

· 2022

Full title: us-2022145265-a1

Patent

us-2022204903-a1

· 2022

Full title: us-2022204903-a1

Patent

us-2022192165-a1

· 2022

Full title: us-2022192165-a1

Patent

us-2022193676-a1

· 2022

Full title: us-2022193676-a1

Patent

us-2022205981-a1

· 2022

Full title: us-2022205981-a1

Patent

us-2022243160-a1

· 2022

Full title: us-2022243160-a1

Patent

us-2022266247-a1

· 2022

Full title: us-2022266247-a1

Patent

us-2022267720-a1

· 2022

Full title: us-2022267720-a1

Patent

us-2022220435-a1

· 2022

Full title: us-2022220435-a1

Patent

us-2022282221-a1

· 2022

Full title: us-2022282221-a1

Patent

us-2022259534-a1

· 2022

Full title: us-2022259534-a1

Patent

us-2022308045-a1

· 2022

Full title: us-2022308045-a1

Patent

us-2022291201-a1

· 2022

Full title: us-2022291201-a1

Patent

us-2022338465-a1

· 2022

Full title: us-2022338465-a1

Patent

us-2022330529-a1

· 2022

Full title: us-2022330529-a1

Patent

us-2022315899-a1

· 2022

Full title: us-2022315899-a1

Patent

us-2022297117-a1

· 2022

Full title: us-2022297117-a1

Patent

us-2022243171-a1

· 2022

Full title: us-2022243171-a1

Patent

us-2022340849-a1

· 2022

Full title: us-2022340849-a1

Patent

us-2022333064-a1

· 2022

Full title: us-2022333064-a1

Patent

us-2022403312-a9

· 2022

Full title: us-2022403312-a9

Patent

us-2022403339-a1

· 2022

Full title: us-2022403339-a1

Patent

us-2022396773-a1

· 2022

Full title: us-2022396773-a1

Patent

us-2022397564-a1

· 2022

Full title: us-2022397564-a1

Patent

us-2022331502-a1

· 2022

Full title: us-2022331502-a1

Patent

us-2022404339-a1

· 2022

Full title: us-2022404339-a1

Patent

us-2022411750-a1

· 2022

Full title: us-2022411750-a1

Patent

us-2023091038-a1

· 2023

Full title: us-2023091038-a1

Patent

us-2023026247-a1

· 2023

Full title: us-2023026247-a1

Patent

us-2023027317-a1

· 2023

Full title: us-2023027317-a1

Patent

us-2023015127-a1

· 2023

Full title: us-2023015127-a1

Patent

us-2023002727-a1

· 2023

Full title: us-2023002727-a1

Patent

us-2023138186-a1

· 2023

Full title: us-2023138186-a1

Patent

us-2023095466-a1

· 2023

Full title: us-2023095466-a1

Patent

us-2023093162-a1

· 2023

Full title: us-2023093162-a1

Patent

us-2023022203-a1

· 2023

Full title: us-2023022203-a1

Patent

us-2023088277-a1

· 2023

Full title: us-2023088277-a1

Patent

us-2023095498-a1

· 2023

Full title: us-2023095498-a1

Patent

us-2023138759-a1

· 2023

Full title: us-2023138759-a1

Patent

us-2023032623-a1

· 2023

Full title: us-2023032623-a1

Patent

us-2023172172-a1

· 2023

Full title: us-2023172172-a1

Patent

us-2023151333-a1

· 2023

Full title: us-2023151333-a1

Patent

us-2023193182-a1

· 2023

Full title: us-2023193182-a1

Patent

us-2023159899-a1

· 2023

Full title: us-2023159899-a1

Patent

us-2023159871-a1

· 2023

Full title: us-2023159871-a1

Patent

us-2023146860-a1

· 2023

Full title: us-2023146860-a1

Patent

us-2023159896-a1

· 2023

Full title: us-2023159896-a1

Patent

us-2023147702-a1

· 2023

Full title: us-2023147702-a1

Patent

us-2023235289-a1

· 2023

Full title: us-2023235289-a1

Patent

us-2023174909-a1

· 2023

Full title: us-2023174909-a1

Patent

us-2023250377-a1

· 2023

Full title: us-2023250377-a1

Patent

us-2023257716-a1

· 2023

Full title: us-2023257716-a1

Patent

us-2023357694-a1

· 2023

Full title: us-2023357694-a1

Patent

us-2023280261-a1

· 2023

Full title: us-2023280261-a1

Patent

us-2023255195-a1

· 2023

Full title: us-2023255195-a1

Patent

us-2023340419-a1

· 2023

Full title: us-2023340419-a1

Patent

us-2023220353-a1

· 2023

Full title: us-2023220353-a1

Patent

us-2023381773-a1

· 2023

Full title: us-2023381773-a1

Patent

us-2023287355-a1

· 2023

Full title: us-2023287355-a1

Patent

us-2023265393-a1

· 2023

Full title: us-2023265393-a1

Patent

us-11066633-b2

· 2021

Full title: us-11066633-b2

Patent

us-11116799-b2

· 2021

Full title: us-11116799-b2

Patent

us-11332717-b2

· 2022

Full title: us-11332717-b2

Patent

us-11365396-b2

· 2022

Full title: us-11365396-b2

Patent

us-11324779-b2

· 2022

Full title: us-11324779-b2

Patent

us-11272695-b2

· 2022

Full title: us-11272695-b2

Patent

us-10323229-b1

· 2019

Full title: us-10323229-b1

Patent

us-11268950-b2

· 2022

Full title: us-11268950-b2

Patent

us-11459542-b2

· 2022

Full title: us-11459542-b2

Patent

us-11401501-b2

· 2022

Full title: us-11401501-b2

Patent

us-11407979-b2

· 2022

Full title: us-11407979-b2

Patent

us-11479752-b2

· 2022

Full title: us-11479752-b2

Patent

us-11326149-b2

· 2022

Full title: us-11326149-b2

Patent

us-11384328-b2

· 2022

Full title: us-11384328-b2

Patent

us-11406975-b2

· 2022

Full title: us-11406975-b2

Patent

us-11542462-b2

· 2023

Full title: us-11542462-b2

Patent

us-11492595-b2

· 2022

Full title: us-11492595-b2

Patent

us-11464640-b2

· 2022

Full title: us-11464640-b2

Patent

us-11473061-b2

· 2022

Full title: us-11473061-b2

Patent

us-11499127-b2

· 2022

Full title: us-11499127-b2

Patent

us-11493428-b2

· 2022

Full title: us-11493428-b2

Patent

us-11566212-b2

· 2023

Full title: us-11566212-b2

Patent

us-11542476-b2

· 2023

Full title: us-11542476-b2

Patent

us-11622546-b2

· 2023

Full title: us-11622546-b2

Patent

us-11542475-b2

· 2023

Full title: us-11542475-b2

Patent

us-11589562-b2

· 2023

Full title: us-11589562-b2

Patent

us-11566231-b2

· 2023

Full title: us-11566231-b2

Patent

us-11547101-b2

· 2023

Full title: us-11547101-b2

Patent

us-11840683-b2

· 2023

Full title: us-11840683-b2

Patent

us-11628437-b2

· 2023

Full title: us-11628437-b2

Patent

us-11628382-b2

· 2023

Full title: us-11628382-b2

Patent

us-11782051-b2

· 2023

Full title: us-11782051-b2

Patent

us-11685900-b2

· 2023

Full title: us-11685900-b2

Patent

us-11629319-b2

· 2023

Full title: us-11629319-b2

Patent

us-11725190-b2

· 2023

Full title: us-11725190-b2

Patent

us-11833512-b2

· 2023

Full title: us-11833512-b2

Patent

us-11845920-b2

· 2023

Full title: us-11845920-b2

Patent

us-11781101-b2

· 2023

Full title: us-11781101-b2

Patent

us-11841361-b2

· 2023

Full title: us-11841361-b2

Patent

us-11820966-b2

· 2023

Full title: us-11820966-b2

Patent

us-11788063-b2

· 2023

Full title: us-11788063-b2

Patent

us-11865536-b2

· 2024

Full title: us-11865536-b2

Patent

us-11834641-b2

· 2023

Full title: us-11834641-b2

Patent

us-11920162-b2

· 2024

Full title: us-11920162-b2

Patent

us-11920114-b2

· 2024

Full title: us-11920114-b2

Patent

us-11913940-b2

· 2024

Full title: us-11913940-b2

Patent

us-11932839-b2

· 2024

Full title: us-11932839-b2

Patent

us-11987813-b2

· 2024

Full title: us-11987813-b2

Patent

us-11925726-b2

· 2024

Full title: us-11925726-b2

Patent

us-11993785-b2

· 2024

Full title: us-11993785-b2

Patent

us-12110507-b2

· 2024

Full title: us-12110507-b2

Patent

us-12054698-b2

· 2024

Full title: us-12054698-b2

Patent

us-11981926-b2

· 2024

Full title: us-11981926-b2

Patent

us-11982668-b2

· 2024

Full title: us-11982668-b2

Patent

us-11920116-b2

· 2024

Full title: us-11920116-b2

Patent

us-12128072-b2

· 2024

Full title: us-12128072-b2

Patent

us-12110479-b2

· 2024

Full title: us-12110479-b2

Patent

us-12180447-b2

· 2024

Full title: us-12180447-b2

Patent

us-12098352-b2

· 2024

Full title: us-12098352-b2

Patent

us-12158464-b2

· 2024

Full title: us-12158464-b2

Patent

us-12100143-b2

· 2024

Full title: us-12100143-b2

Patent

us-12134759-b2

· 2024

Full title: us-12134759-b2

Patent

us-12180446-b2

· 2024

Full title: us-12180446-b2

Patent

us-12377413-b2

· 2025

Full title: us-12377413-b2

Patent

us-12180507-b2

· 2024

Full title: us-12180507-b2

Patent

us-12247223-b2

· 2025

Full title: us-12247223-b2

Patent

us-12241049-b2

· 2025

Full title: us-12241049-b2

Patent

us-12252712-b2

· 2025

Full title: us-12252712-b2

Patent

us-12351820-b2

· 2025

Full title: us-12351820-b2

Patent

us-12303806-b2

· 2025

Full title: us-12303806-b2

Patent

us-12378528-b2

· 2025

Full title: us-12378528-b2

Patent

us-12275957-b2

· 2025

Full title: us-12275957-b2

Patent

us-12305153-b2

· 2025

Full title: us-12305153-b2

Patent

us-12384993-b2

· 2025

Full title: us-12384993-b2

Patent

us-12018284-b2

· 2024

Full title: us-12018284-b2

Patent

us-12270016-b1

· 2025

Full title: us-12270016-b1

Patent

us-2001055806-a1

· 2001

Full title: us-2001055806-a1

Patent

us-2003064358-a1

· 2003

Full title: us-2003064358-a1

Patent

us-2003017142-a1

· 2003

Full title: us-2003017142-a1

Patent

us-2003044883-a1

· 2003

Full title: us-2003044883-a1

Patent

us-12391926-b2

· 2025

Full title: us-12391926-b2

Patent

us-12448607-b2

· 2025

Full title: us-12448607-b2

Patent

us-2004006373-a1

· 2004

Full title: us-2004006373-a1

Patent

us-2004197907-a1

· 2004

Full title: us-2004197907-a1

Patent

us-2004219513-a1

· 2004

Full title: us-2004219513-a1

Patent

us-2004228795-a1

· 2004

Full title: us-2004228795-a1

Patent

us-2004214226-a1

· 2004

Full title: us-2004214226-a1

Patent

us-2006172416-a1

· 2006

Full title: us-2006172416-a1

Patent

us-2004152149-a1

· 2004

Full title: us-2004152149-a1

Patent

us-2005260745-a1

· 2005

Full title: us-2005260745-a1

Patent

us-2006026701-a1

· 2006

Full title: us-2006026701-a1

Patent

us-2006190043-a1

· 2006

Full title: us-2006190043-a1

Patent

us-2007037277-a1

· 2007

Full title: us-2007037277-a1

Patent

us-2007044162-a1

· 2007

Full title: us-2007044162-a1

Patent

us-2007224677-a1

· 2007

Full title: us-2007224677-a1

Patent

us-2007186289-a1

· 2007

Full title: us-2007186289-a1

Patent

us-2008293133-a1

· 2008

Full title: us-2008293133-a1

Patent

us-2008288399-a1

· 2008

Full title: us-2008288399-a1

Patent

us-2008070304-a1

· 2008

Full title: us-2008070304-a1

Patent

us-2007048727-a1

· 2007

Full title: us-2007048727-a1

Patent

us-2009011504-a1

· 2009

Full title: us-2009011504-a1

Patent

us-2008102478-a1

· 2008

Full title: us-2008102478-a1

Patent

us-2009191631-a1

· 2009

Full title: us-2009191631-a1

Patent

us-2009117584-a1

· 2009

Full title: us-2009117584-a1

Patent

us-2009068701-a1

· 2009

Full title: us-2009068701-a1

Patent

us-2009038020-a1

· 2009

Full title: us-2009038020-a1

Patent

us-2010275278-a1

· 2010

Full title: us-2010275278-a1

Patent

us-2011091930-a1

· 2011

Full title: us-2011091930-a1

Patent

us-2010122357-a1

· 2010

Full title: us-2010122357-a1

Patent

us-2010056390-a1

· 2010

Full title: us-2010056390-a1

Patent

us-2009104164-a1

· 2009

Full title: us-2009104164-a1

Patent

us-2010173333-a1

· 2010

Full title: us-2010173333-a1

Patent

us-2011086427-a1

· 2011

Full title: us-2011086427-a1

Patent

us-2011229970-a1

· 2011

Full title: us-2011229970-a1

Patent

us-2012083425-a1

· 2012

Full title: us-2012083425-a1

Patent

us-2013143230-a1

· 2013

Full title: us-2013143230-a1

Patent

us-2012156670-a1

· 2012

Full title: us-2012156670-a1

Patent

us-2012035742-a1

· 2012

Full title: us-2012035742-a1

Patent

us-2012009672-a1

· 2012

Full title: us-2012009672-a1

Patent

us-2013115606-a1

· 2013

Full title: us-2013115606-a1

Patent

us-2012231976-a1

· 2012

Full title: us-2012231976-a1

Patent

us-2013273589-a1

· 2013

Full title: us-2013273589-a1

Patent

us-2014273220-a1

· 2014

Full title: us-2014273220-a1

Patent

us-2013266939-a1

· 2013

Full title: us-2013266939-a1

Patent

us-2013198874-a1

· 2013

Full title: us-2013198874-a1

Patent

us-2013130301-a1

· 2013

Full title: us-2013130301-a1

Patent

us-2014011197-a1

· 2014

Full title: us-2014011197-a1

Patent

us-2015184124-a1

· 2015

Full title: us-2015184124-a1

Patent

us-2014221225-a1

· 2014

Full title: us-2014221225-a1

Patent

us-2014134662-a1

· 2014

Full title: us-2014134662-a1

Patent

us-2013295598-a1

· 2013

Full title: us-2013295598-a1

Patent

us-2014287960-a1

· 2014

Full title: us-2014287960-a1

Patent

us-2014274802-a1

· 2014

Full title: us-2014274802-a1

Patent

us-2014373186-a1

· 2014

Full title: us-2014373186-a1

Patent

us-2015074835-a1

· 2015

Full title: us-2015074835-a1

Patent

us-2014274953-a1

· 2014

Full title: us-2014274953-a1

Patent

us-2014363473-a1

· 2014

Full title: us-2014363473-a1

Patent

us-2015004273-a1

· 2015

Full title: us-2015004273-a1

Patent

us-2015253232-a1

· 2015

Full title: us-2015253232-a1

Patent

us-2015264901-a1

· 2015

Full title: us-2015264901-a1

Patent

us-2015252328-a1

· 2015

Full title: us-2015252328-a1

Patent

us-2015240194-a1

· 2015

Full title: us-2015240194-a1

Patent

us-2015240203-a1

· 2015

Full title: us-2015240203-a1

Patent

us-2015275176-a1

· 2015

Full title: us-2015275176-a1

Patent

us-2015282459-a1

· 2015

Full title: us-2015282459-a1

Patent

us-10119107-b2

· 2018

Full title: us-10119107-b2

Patent

us-10400219-b2

· 2019

Full title: us-10400219-b2

Patent

us-10517731-b2

· 2019

Full title: us-10517731-b2

Patent

us-10717966-b2

· 2020

Full title: us-10717966-b2

Patent

us-10688221-b2

· 2020

Full title: us-10688221-b2

Patent

us-10801015-b2

· 2020

Full title: us-10801015-b2

Patent

us-11001811-b2

· 2021

Full title: us-11001811-b2

Patent

us-11230688-b2

· 2022

Full title: us-11230688-b2

Patent

us-11778995-b2

· 2023

Full title: us-11778995-b2

Patent

us-11952592-b2

· 2024

Full title: us-11952592-b2

Patent

us-12241085-b2

· 2025

Full title: us-12241085-b2

Patent

us-2003033615-a1

· 2003

Full title: us-2003033615-a1

Patent

us-2006154235-a1

· 2006

Full title: us-2006154235-a1

Patent

us-2012208211-a1

· 2012

Full title: us-2012208211-a1

Patent

us-2016017283-a1

· 2016

Full title: us-2016017283-a1

Patent

us-2015079673-a1

· 2015

Full title: us-2015079673-a1

Patent

us-2016281064-a1

· 2016

Full title: us-2016281064-a1

Patent

us-2018057796-a1

· 2018

Full title: us-2018057796-a1

Patent

us-2018312810-a1

· 2018

Full title: us-2018312810-a1

Patent

us-2019040348-a1

· 2019

Full title: us-2019040348-a1

Patent

us-2019249137-a1

· 2019

Full title: us-2019249137-a1

Patent

us-2020087628-a1

· 2020

Full title: us-2020087628-a1

Patent

us-2020190479-a1

· 2020

Full title: us-2020190479-a1

Patent

us-2021054323-a1

· 2021

Full title: us-2021054323-a1

Patent

us-2021324311-a1

· 2021

Full title: us-2021324311-a1

Patent

us-2022095596-a1

· 2022

Full title: us-2022095596-a1

Patent

us-2022217970-a1

· 2022

Full title: us-2022217970-a1

Patent

us-2022250055-a1

· 2022

Full title: us-2022250055-a1

Patent

us-2023002714-a1

· 2023

Full title: us-2023002714-a1

Patent

us-2023357690-a1

· 2023

Full title: us-2023357690-a1

Patent

us-2024026263-a1

· 2024

Full title: us-2024026263-a1

Patent

us-2023383262-a1

· 2023

Full title: us-2023383262-a1

Patent

us-2024150692-a1

· 2024

Full title: us-2024150692-a1

Patent

us-2024279612-a1

· 2024

Full title: us-2024279612-a1

Patent

us-2024344004-a1

· 2024

Full title: us-2024344004-a1

Patent

us-2024228976-a1

· 2024

Full title: us-2024228976-a1

Patent

us-2025034530-a1

· 2025

Full title: us-2025034530-a1

Patent

us-2024376437-a1

· 2024

Full title: us-2024376437-a1

Patent

us-5624839-a

· 1997

Full title: us-5624839-a

Patent

us-5569812-a

· 1996

Full title: us-5569812-a

Patent

us-7022506-b2

· 2006

Full title: us-7022506-b2

3. Authors & Profiles

Run data extraction first

Find authors first. Run extraction before finding authors.

4. Email Outreach

Generate emails first. Find authors, then generate emails.

Pharma Investment In Primary Human Cell In Vitro M

1. Documents

Full text available

Metadata only

2. Data Extraction

3. Authors & Profiles

4. Email Outreach

Settings

Edit Email