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Pre Clinical Cell Line Protocols For Bg C137

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1. Documents

73
13 papers 55 patents 5 theses
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Paper A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer
Skórzewska, Magdalena; Gęca, Katarzyna; Polkowski, Wojciech · 2023 · Cancers · DOI
Full title: A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer
Authors: Skórzewska, Magdalena; Gęca, Katarzyna; Polkowski, Wojciech
Year: 2023
Venue: Cancers
Paper FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
Szymczyk, Jakub; Służalska, Katarzyna Dominika; Materla, Izabela et al. · 2021 · Cancers · DOI
Full title: FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
Authors: Szymczyk, Jakub; Służalska, Katarzyna Dominika; Materla, Izabela; Opaliński, Łukasz; Otlewski, Jacek; Zakrzewska, Małgorzata
Year: 2021
Venue: Cancers
Paper The beginning of the era of precision medicine for gastric cancer with fibroblast growth factor receptor 2 aberration
Ooki, Akira; Yamaguchi, Kensei · 2021 · Gastric Cancer · DOI
Full title: The beginning of the era of precision medicine for gastric cancer with fibroblast growth factor receptor 2 aberration
Authors: Ooki, Akira; Yamaguchi, Kensei
Year: 2021
Venue: Gastric Cancer
Paper The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies
Nguyen, Anh L.; Facey, Caroline O.; Boman, Bruce M. · 2024 · Cancers · DOI
Full title: The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies
Authors: Nguyen, Anh L.; Facey, Caroline O.; Boman, Bruce M.
Year: 2024
Venue: Cancers
Paper Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Lei, Josh Haipeng; Deng, Chu‐Xia · 2017 · International Journal of Biological Sciences · DOI
Full title: Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Authors: Lei, Josh Haipeng; Deng, Chu‐Xia
Year: 2017
Venue: International Journal of Biological Sciences
Paper Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers
Shan, Khine; Dalal, Shivani; Dar, Nyein Nyein Thaw et al. · 2024 · International Journal of Molecular Sciences · DOI
Full title: Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers
Authors: Shan, Khine; Dalal, Shivani; Dar, Nyein Nyein Thaw; McLish, Omani; Salzberg, Matthew; Pico, Brian
Year: 2024
Venue: International Journal of Molecular Sciences
Thesis Quantitative analysis of cellular processing of Antibody-Drug Conjugates
Maass, Katie F · 2016 · Massachusetts Institute of Technology (MIT) · DOI
Full title: Quantitative analysis of cellular processing of Antibody-Drug Conjugates
Authors: Maass, Katie F
Year: 2016
Venue: Massachusetts Institute of Technology (MIT)
Thesis Development of Therapies for Treatment of Aggressive Cancers: Lessons from the Past and Current Perspectives
Arnold, Jennifer · 2022 · OhioLINK Electronic Theses and Dissertations · DOI
Full title: Development of Therapies for Treatment of Aggressive Cancers: Lessons from the Past and Current Perspectives
Authors: Arnold, Jennifer
Year: 2022
Venue: OhioLINK Electronic Theses and Dissertations
Thesis Characterization of FGFR Signaling in Prostate Cancer Stem Cells and Inhibition via TKI treatment
Ko, Juyeon · 2021 · University of California, San Diego (UCSD) · DOI
Full title: Characterization of FGFR Signaling in Prostate Cancer Stem Cells and Inhibition via TKI treatment
Authors: Ko, Juyeon
Year: 2021
Venue: University of California, San Diego (UCSD)
Thesis Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer
Lau, DK; Collin, JP; Mariadason, JM · 2024 · University of Melbourne · DOI
Full title: Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer
Authors: Lau, DK; Collin, JP; Mariadason, JM
Year: 2024
Venue: University of Melbourne
Patent us-2017145102-a1
· 2017
Full title: us-2017145102-a1
Year: 2017
Patent us-2019153105-a1
· 2019
Full title: us-2019153105-a1
Year: 2019
Patent us-2019094229-a1
· 2019
Full title: us-2019094229-a1
Year: 2019
Patent us-2019049432-a1
· 2019
Full title: us-2019049432-a1
Year: 2019
Patent us-2020347141-a1
· 2020
Full title: us-2020347141-a1
Year: 2020
Patent us-2022175722-a1
· 2022
Full title: us-2022175722-a1
Year: 2022
Patent us-2022162323-a1
· 2022
Full title: us-2022162323-a1
Year: 2022
Patent us-2023055566-a1
· 2023
Full title: us-2023055566-a1
Year: 2023
Patent us-2022010020-a1
· 2022
Full title: us-2022010020-a1
Year: 2022
Patent us-2023052256-a1
· 2023
Full title: us-2023052256-a1
Year: 2023
Patent us-2024190973-a1
· 2024
Full title: us-2024190973-a1
Year: 2024
Patent us-2023295308-a1
· 2023
Full title: us-2023295308-a1
Year: 2023
Patent us-2023052680-a1
· 2023
Full title: us-2023052680-a1
Year: 2023
Patent us-2025032458-a1
· 2025
Full title: us-2025032458-a1
Year: 2025
Patent us-2025243284-a1
· 2025
Full title: us-2025243284-a1
Year: 2025
Patent us-2024101683-a1
· 2024
Full title: us-2024101683-a1
Year: 2024
Patent us-8101721-b2
· 2012
Full title: us-8101721-b2
Year: 2012
Patent us-2025277041-a1
· 2025
Full title: us-2025277041-a1
Year: 2025
Patent us-2025222125-a1
· 2025
Full title: us-2025222125-a1
Year: 2025
Patent us-8962655-b2
· 2015
Full title: us-8962655-b2
Year: 2015
Patent us-8173134-b2
· 2012
Full title: us-8173134-b2
Year: 2012
Patent us-8580936-b2
· 2013
Full title: us-8580936-b2
Year: 2013
Patent us-9192683-b2
· 2015
Full title: us-9192683-b2
Year: 2015
Patent us-10138301-b2
· 2018
Full title: us-10138301-b2
Year: 2018
Patent us-11866502-b2
· 2024
Full title: us-11866502-b2
Year: 2024
Patent us-2004014024-a1
· 2004
Full title: us-2004014024-a1
Year: 2004
Patent us-2010048620-a1
· 2010
Full title: us-2010048620-a1
Year: 2010
Patent us-2010047251-a1
· 2010
Full title: us-2010047251-a1
Year: 2010
Patent us-2011281302-a1
· 2011
Full title: us-2011281302-a1
Year: 2011
Patent us-2015023989-a1
· 2015
Full title: us-2015023989-a1
Year: 2015
Patent us-2014322220-a1
· 2014
Full title: us-2014322220-a1
Year: 2014
Patent us-2015050273-a1
· 2015
Full title: us-2015050273-a1
Year: 2015
Patent us-2016209417-a1
· 2016
Full title: us-2016209417-a1
Year: 2016

Metadata only

Paper Abstract 245: Preclinical development of HDM2020, a novel ADC targeting FGFR2b, in gastric cancer (GC) and squamous non-small cell lung cancer (sq-NSCLC) xenograft models
Tingyang Wang; Liubin Guo; Kuan Lu et al. · 2025 · Cancer Research · DOI
Full title: Abstract 245: Preclinical development of HDM2020, a novel ADC targeting FGFR2b, in gastric cancer (GC) and squamous non-small cell lung cancer (sq-NSCLC) xenograft models
Authors: Tingyang Wang; Liubin Guo; Kuan Lu; Hao Pan; Yang Chen; Zhaoxing Yu; Yayun Zhao; Shengxing Zhao; Qingli We; Ruizhe Wang; Yan Xia; Hongwen Li; D. Liu
Year: 2025
Venue: Cancer Research
Paper Abstract 4769: Characterization of novel humanized FGFR2b antibody-based ADCs site-specifically conjugated with topoisomerase I inhibitor payload in preclinical tumor models
Fei Teng; Huanhuan Guo; Hongjun Li et al. · 2025 · Cancer Research · DOI
Full title: Abstract 4769: Characterization of novel humanized FGFR2b antibody-based ADCs site-specifically conjugated with topoisomerase I inhibitor payload in preclinical tumor models
Authors: Fei Teng; Huanhuan Guo; Hongjun Li; Lizhi Qin; Xin-gang Yao; Lei Shi; Yi Gu; Xueming Qian
Year: 2025
Venue: Cancer Research
Paper 819TiP A phase I clinical study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of HDM2020 (FGFR2b-ADC) in patients with advanced solid tumors
R. Xu; D. Ruan; F. Liu et al. · 2025 · Annals of Oncology · DOI
Full title: 819TiP A phase I clinical study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of HDM2020 (FGFR2b-ADC) in patients with advanced solid tumors
Authors: R. Xu; D. Ruan; F. Liu; X. Liu; L. Zhong; Y. Ling; G. Chen; J. Pang; R. Zeng; J. Xu
Year: 2025
Venue: Annals of Oncology
Paper Abstract 3778: Preclinical evaluation of BG-C137, a potential first-in-class FGFR2b-targeting ADC, for the treatment of FGFR2b-expressing cancer
Yibin Xu; Xiaolin Su; Qiming Xu et al. · 2025 · Cancer Research · DOI
Full title: Abstract 3778: Preclinical evaluation of BG-C137, a potential first-in-class FGFR2b-targeting ADC, for the treatment of FGFR2b-expressing cancer
Authors: Yibin Xu; Xiaolin Su; Qiming Xu; Mengran Qian; Tai-Zhe Zhang; Mei-Hsuan Tsai; Ruyue Ji; Junna Jiang; Bin Shao; Zhuang Yuan; Jiyuan Zhang; Xiaomin Song; Zhitao Wan; Xiao-Qiang Tang; Yue Wu; Charng-Sheng Tsai; Chichi Huang; Lai Wang; Zhirong Shen
Year: 2025
Venue: Cancer Research
Paper Brave new world—new and emerging treatments for gastric cancer
Lynch, Emer; Duffy, Austin G.; Kelly, Ronan J. · 2023 · Chinese Clinical Oncology · DOI
Full title: Brave new world—new and emerging treatments for gastric cancer
Authors: Lynch, Emer; Duffy, Austin G.; Kelly, Ronan J.
Year: 2023
Venue: Chinese Clinical Oncology
Paper SCR-A002, a novel FGFR2b-targeting antibody-drug-conjugate for solid tumors.
Yayuan Fu; Yuanjie Ge; Xiaohui Shao et al. · 2024 · Journal of Clinical Oncology · DOI
Full title: SCR-A002, a novel FGFR2b-targeting antibody-drug-conjugate for solid tumors.
Authors: Yayuan Fu; Yuanjie Ge; Xiaohui Shao; Qi Deng; Chunlei Xia; Renhong Tang
Year: 2024
Venue: Journal of Clinical Oncology
Paper Novel Biomarkers of Gastric Cancer: Current Research and Future Perspectives
Sato, Yasushi; Okamoto, Koichi; Kawano, Yutaka et al. · 2023 · Journal of Clinical Medicine · DOI
Full title: Novel Biomarkers of Gastric Cancer: Current Research and Future Perspectives
Authors: Sato, Yasushi; Okamoto, Koichi; Kawano, Yutaka; Kasai, Akinari; Kawaguchi, Tomoyuki; Sagawa, Tamotsu; Sogabe, Masahiro; Miyamoto, Hiroshi; Takayama, Tetsuji
Year: 2023
Venue: Journal of Clinical Medicine
Thesis Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings
Moraes, Jane Zveiter de · 2016 · Universidade de São Paulo – USP Digital Library · DOI
Full title: Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings
Authors: Moraes, Jane Zveiter de
Year: 2016
Venue: Universidade de São Paulo – USP Digital Library
Patent us-2019345250-a1
· 2019
Full title: us-2019345250-a1
Year: 2019
Patent us-2020085946-a1
· 2020
Full title: us-2020085946-a1
Year: 2020
Patent us-8481688-b2
· 2013
Full title: us-8481688-b2
Year: 2013
Patent us-9415118-b2
· 2016
Full title: us-9415118-b2
Year: 2016
Patent us-9382324-b2
· 2016
Full title: us-9382324-b2
Year: 2016
Patent us-9498532-b2
· 2016
Full title: us-9498532-b2
Year: 2016
Patent us-9834609-b2
· 2017
Full title: us-9834609-b2
Year: 2017
Patent us-10881734-b2
· 2021
Full title: us-10881734-b2
Year: 2021
Patent us-2010196364-a1
· 2010
Full title: us-2010196364-a1
Year: 2010
Patent us-2013252270-a1
· 2013
Full title: us-2013252270-a1
Year: 2013
Patent us-2012134994-a1
· 2012
Full title: us-2012134994-a1
Year: 2012
Patent us-2013288305-a1
· 2013
Full title: us-2013288305-a1
Year: 2013
Patent us-2014193899-a1
· 2014
Full title: us-2014193899-a1
Year: 2014
Patent us-2014308201-a1
· 2014
Full title: us-2014308201-a1
Year: 2014
Patent us-2014301946-a1
· 2014
Full title: us-2014301946-a1
Year: 2014
Patent us-2016362496-a1
· 2016
Full title: us-2016362496-a1
Year: 2016
Patent us-2017008964-a1
· 2017
Full title: us-2017008964-a1
Year: 2017
Patent us-2016244525-a1
· 2016
Full title: us-2016244525-a1
Year: 2016
Patent us-2018071338-a1
· 2018
Full title: us-2018071338-a1
Year: 2018
Patent us-2017106095-a1
· 2017
Full title: us-2017106095-a1
Year: 2017
Patent us-2018161446-a1
· 2018
Full title: us-2018161446-a1
Year: 2018
Patent us-2018094063-a1
· 2018
Full title: us-2018094063-a1
Year: 2018

2. Data Extraction

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0/43 extracted
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Paper
A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer
Skórzewska, Magdalena; Gęca, Katarzyna; Polkowski, Wojciech · 2023
Full title: A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer
Authors: Skórzewska, Magdalena; Gęca, Katarzyna; Polkowski, Wojciech
Paper
FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
Szymczyk, Jakub; Służalska, Katarzyna Dominika; Materla, Izabela et al. · 2021
Full title: FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
Authors: Szymczyk, Jakub; Służalska, Katarzyna Dominika; Materla, Izabela; Opaliński, Łukasz; Otlewski, Jacek; Zakrzewska, Małgorzata
Paper
The beginning of the era of precision medicine for gastric cancer with fibroblast growth factor receptor 2 aberration
Ooki, Akira; Yamaguchi, Kensei · 2021
Full title: The beginning of the era of precision medicine for gastric cancer with fibroblast growth factor receptor 2 aberration
Authors: Ooki, Akira; Yamaguchi, Kensei
Paper
The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies
Nguyen, Anh L.; Facey, Caroline O.; Boman, Bruce M. · 2024
Full title: The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies
Authors: Nguyen, Anh L.; Facey, Caroline O.; Boman, Bruce M.
Paper
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Lei, Josh Haipeng; Deng, Chu‐Xia · 2017
Full title: Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Authors: Lei, Josh Haipeng; Deng, Chu‐Xia
Paper
Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers
Shan, Khine; Dalal, Shivani; Dar, Nyein Nyein Thaw et al. · 2024
Full title: Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers
Authors: Shan, Khine; Dalal, Shivani; Dar, Nyein Nyein Thaw; McLish, Omani; Salzberg, Matthew; Pico, Brian
Thesis
Quantitative analysis of cellular processing of Antibody-Drug Conjugates
Maass, Katie F · 2016
Full title: Quantitative analysis of cellular processing of Antibody-Drug Conjugates
Authors: Maass, Katie F
Thesis
Development of Therapies for Treatment of Aggressive Cancers: Lessons from the Past and Current Perspectives
Arnold, Jennifer · 2022
Full title: Development of Therapies for Treatment of Aggressive Cancers: Lessons from the Past and Current Perspectives
Authors: Arnold, Jennifer
Thesis
Characterization of FGFR Signaling in Prostate Cancer Stem Cells and Inhibition via TKI treatment
Ko, Juyeon · 2021
Full title: Characterization of FGFR Signaling in Prostate Cancer Stem Cells and Inhibition via TKI treatment
Authors: Ko, Juyeon
Thesis
Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer
Lau, DK; Collin, JP; Mariadason, JM · 2024
Full title: Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer
Authors: Lau, DK; Collin, JP; Mariadason, JM
Patent
us-2017145102-a1
· 2017
Full title: us-2017145102-a1
Patent
us-2019153105-a1
· 2019
Full title: us-2019153105-a1
Patent
us-2019094229-a1
· 2019
Full title: us-2019094229-a1
Patent
us-2019049432-a1
· 2019
Full title: us-2019049432-a1
Patent
us-2020347141-a1
· 2020
Full title: us-2020347141-a1
Patent
us-2022175722-a1
· 2022
Full title: us-2022175722-a1
Patent
us-2022162323-a1
· 2022
Full title: us-2022162323-a1
Patent
us-2023055566-a1
· 2023
Full title: us-2023055566-a1
Patent
us-2022010020-a1
· 2022
Full title: us-2022010020-a1
Patent
us-2023052256-a1
· 2023
Full title: us-2023052256-a1
Patent
us-2024190973-a1
· 2024
Full title: us-2024190973-a1
Patent
us-2023295308-a1
· 2023
Full title: us-2023295308-a1
Patent
us-2023052680-a1
· 2023
Full title: us-2023052680-a1
Patent
us-2025032458-a1
· 2025
Full title: us-2025032458-a1
Patent
us-2025243284-a1
· 2025
Full title: us-2025243284-a1
Patent
us-2024101683-a1
· 2024
Full title: us-2024101683-a1
Patent
us-8101721-b2
· 2012
Full title: us-8101721-b2
Patent
us-2025277041-a1
· 2025
Full title: us-2025277041-a1
Patent
us-2025222125-a1
· 2025
Full title: us-2025222125-a1
Patent
us-8962655-b2
· 2015
Full title: us-8962655-b2
Patent
us-8173134-b2
· 2012
Full title: us-8173134-b2
Patent
us-8580936-b2
· 2013
Full title: us-8580936-b2
Patent
us-9192683-b2
· 2015
Full title: us-9192683-b2
Patent
us-10138301-b2
· 2018
Full title: us-10138301-b2
Patent
us-11866502-b2
· 2024
Full title: us-11866502-b2
Patent
us-2004014024-a1
· 2004
Full title: us-2004014024-a1
Patent
us-2010048620-a1
· 2010
Full title: us-2010048620-a1
Patent
us-2010047251-a1
· 2010
Full title: us-2010047251-a1
Patent
us-2011281302-a1
· 2011
Full title: us-2011281302-a1
Patent
us-2015023989-a1
· 2015
Full title: us-2015023989-a1
Patent
us-2014322220-a1
· 2014
Full title: us-2014322220-a1
Patent
us-2015050273-a1
· 2015
Full title: us-2015050273-a1
Patent
us-2016209417-a1
· 2016
Full title: us-2016209417-a1

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