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Evidence For Pd 1 Pd L1 Combination Immunotherapie

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Paper Type I interferon-mediated tumor immunity and its role in immunotherapy

Yu, Renren, Zhu, Bo, Chen, Degao · 2022 · Cellular and Molecular Life Sciences · DOI

Full title: Type I interferon-mediated tumor immunity and its role in immunotherapy

Authors: Yu, Renren, Zhu, Bo, Chen, Degao

Year: 2022

Venue: Cellular and Molecular Life Sciences

DOI: https://doi.org/10.1007/s00018-022-04219-z

Paper Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Foy, Susan P., Mandl, Stefanie, Cruz, Tracy dela, Cote, Joseph, Gordon, Evan, Trent, Erica, Delcayre, Alain, Breitmeyer, James B., Franzusoff, Alex, Rountree, Ryan B. · 2016 · Cancer Immunology Immunotherapy · DOI

Full title: Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Authors: Foy, Susan P., Mandl, Stefanie, Cruz, Tracy dela, Cote, Joseph, Gordon, Evan, Trent, Erica, Delcayre, Alain, Breitmeyer, James B., Franzusoff, Alex, Rountree, Ryan B.

Year: 2016

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-016-1816-7

Paper Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Eijs, Mick J M van, Verheijden, Rik J., Wees, Stefanie A. van der, Nierkens, Stefan, Lindert, Anne S. R. van, Suijkerbuijk, Karijn P.M., Wijk, Femke van, Meyaard, Linde, Kuball, Jürgen, Oldenburg, Bas, Leusen, Jeanette H.W. · 2023 · Cancer Immunology Immunotherapy · DOI

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Authors: Eijs, Mick J M van, Verheijden, Rik J., Wees, Stefanie A. van der, Nierkens, Stefan, Lindert, Anne S. R. van, Suijkerbuijk, Karijn P.M., Wijk, Femke van, Meyaard, Linde, Kuball, Jürgen, Oldenburg, Bas, Leusen, Jeanette H.W.

Year: 2023

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-023-03541-0

Paper Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Sundström, E., Huang, Xueting, Wiemer, Andrew J. · 2025 · Cancer Immunology Immunotherapy · DOI

Full title: Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Authors: Sundström, E., Huang, Xueting, Wiemer, Andrew J.

Year: 2025

Venue: Cancer Immunology Immunotherapy

DOI: https://doi.org/10.1007/s00262-025-04128-7

Paper Mechanisms of resistance to immune checkpoint inhibitors

Jenkins, Russell W., Barbie, David A., Flaherty, Keith T. · 2018 · British Journal of Cancer · DOI

Full title: Mechanisms of resistance to immune checkpoint inhibitors

Authors: Jenkins, Russell W., Barbie, David A., Flaherty, Keith T.

Year: 2018

Venue: British Journal of Cancer

DOI: https://doi.org/10.1038/bjc.2017.434

Paper T-cell exhaustion in the tumor microenvironment

Jiang, Yuyong, Li, Yongsheng, Zhu, Bo · 2015 · Cell Death and Disease · DOI

Full title: T-cell exhaustion in the tumor microenvironment

Authors: Jiang, Yuyong, Li, Yongsheng, Zhu, Bo

Year: 2015

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/cddis.2015.162

Paper Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana, Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Jänne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidhu P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok‐Kin, Hammerman, Peter S. · 2016 · Nature Communications · DOI

Full title: Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Authors: Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana, Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Jänne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidhu P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok‐Kin, Hammerman, Peter S.

Year: 2016

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms10501

Paper DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Vanpouille‐Box, Claire, Alard, Amandine, Aryankalayil, Molykutty J., Sarfraz, Yasmeen, Diamond, Julie M., Schneider, Robert J., Inghirami, Giorgio, Coleman, C. Norman, Formenti, Silvia C., Demaria, Sandra · 2017 · Nature Communications · DOI

Full title: DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Authors: Vanpouille‐Box, Claire, Alard, Amandine, Aryankalayil, Molykutty J., Sarfraz, Yasmeen, Diamond, Julie M., Schneider, Robert J., Inghirami, Giorgio, Coleman, C. Norman, Formenti, Silvia C., Demaria, Sandra

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms15618

Paper Comprehensive review of targeted therapy for colorectal cancer

Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan · 2020 · Signal Transduction and Targeted Therapy · DOI

Full title: Comprehensive review of targeted therapy for colorectal cancer

Authors: Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan

Year: 2020

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-020-0116-z

Paper Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail · 2020 · British Journal of Cancer · DOI

Full title: Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Authors: Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail

Year: 2020

Venue: British Journal of Cancer

DOI: https://doi.org/10.1038/s41416-020-01048-4

Paper Neoantigen cancer vaccine augments anti-CTLA-4 efficacy

Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio · 2022 · npj Vaccines · DOI

Full title: Neoantigen cancer vaccine augments anti-CTLA-4 efficacy

Authors: Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio

Year: 2022

Venue: npj Vaccines

DOI: https://doi.org/10.1038/s41541-022-00433-9

Paper A view on drug resistance in cancer

Vasan, Neil, Baselga, José, Hyman, David M. · 2019 · Nature · DOI

Full title: A view on drug resistance in cancer

Authors: Vasan, Neil, Baselga, José, Hyman, David M.

Year: 2019

Venue: Nature

DOI: https://doi.org/10.1038/s41586-019-1730-1

Paper Cancer immunotherapy: the beginning of the end of cancer?

Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M. · 2016 · BMC Medicine · DOI

Full title: Cancer immunotherapy: the beginning of the end of cancer?

Authors: Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M.

Year: 2016

Venue: BMC Medicine

DOI: https://doi.org/10.1186/s12916-016-0623-5

Paper Development of therapeutic antibodies for the treatment of diseases

Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung · 2020 · Journal of Biomedical Science · DOI

Full title: Development of therapeutic antibodies for the treatment of diseases

Authors: Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung

Year: 2020

Venue: Journal of Biomedical Science

DOI: https://doi.org/10.1186/s12929-019-0592-z

Paper Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia · 2019 · Molecular Cancer · DOI

Full title: Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

Authors: Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia

Year: 2019

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-019-1091-2

Paper Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Yi, Ming; Zheng, Xiaoli; Niu, Mengke et al. · 2022 · Molecular Cancer · DOI

Full title: Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Authors: Yi, Ming; Zheng, Xiaoli; Niu, Mengke; Zhu, Shuangli; Ge, Hong; Wu, Kongming

Year: 2022

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-021-01489-2

Paper Lung cancer immunotherapy: progress, pitfalls, and promises

Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K. · 2023 · Molecular Cancer · DOI

Full title: Lung cancer immunotherapy: progress, pitfalls, and promises

Authors: Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K.

Year: 2023

Venue: Molecular Cancer

DOI: https://doi.org/10.1186/s12943-023-01740-y

Paper Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

Ascierto, Paolo A., Puzanov, Igor, Agarwala, Sanjiv S., Bifulco, Carlo, Botti, Gerardo, Caracò, Corrado, Ciliberto, Gennaro, Davies, Michael A., Dummer, Reinhard, Ferrone, Soldano, Gajewski, Thomas F., Garbe, Claus, Luke, Jason J., Marincola, Francesco M., Masucci, Giuseppe, Mehnert, Janice M., Mozzillo, N, Palmieri, Giuseppe, Postow, Michael A., Schoenberger, Stephen P., Wang, Ena, Hu, Hong‐Ming · 2018 · Journal of Translational Medicine · DOI

Full title: Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

Authors: Ascierto, Paolo A., Puzanov, Igor, Agarwala, Sanjiv S., Bifulco, Carlo, Botti, Gerardo, Caracò, Corrado, Ciliberto, Gennaro, Davies, Michael A., Dummer, Reinhard, Ferrone, Soldano, Gajewski, Thomas F., Garbe, Claus, Luke, Jason J., Marincola, Francesco M., Masucci, Giuseppe, Mehnert, Janice M., Mozzillo, N, Palmieri, Giuseppe, Postow, Michael A., Schoenberger, Stephen P., Wang, Ena, Hu, Hong‐Ming

Year: 2018

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-018-1568-6

Paper Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy

Su, Xin, Li, Jian, Xu, Xiao‐Ming, Ye, Yuanyi, Wang, Cailiu, Pang, Guanglong, Liu, Wenxiu, Liu, Ang, Zhao, Changchun, Hao, Xiangyong · 2024 · Journal of Translational Medicine · DOI

Full title: Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy

Authors: Su, Xin, Li, Jian, Xu, Xiao‐Ming, Ye, Yuanyi, Wang, Cailiu, Pang, Guanglong, Liu, Wenxiu, Liu, Ang, Zhao, Changchun, Hao, Xiangyong

Year: 2024

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-024-05552-6

Paper Gastric cancer treatment: recent progress and future perspectives

Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua · 2023 · Journal of Hematology & Oncology · DOI

Full title: Gastric cancer treatment: recent progress and future perspectives

Authors: Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua

Year: 2023

Venue: Journal of Hematology & Oncology

DOI: https://doi.org/10.1186/s13045-023-01451-3

Paper Combination of CTLA-4 and PD-1 blockers for treatment of cancer

Rotte, Anand · 2019 · Journal of Experimental & Clinical Cancer Research · DOI

Full title: Combination of CTLA-4 and PD-1 blockers for treatment of cancer

Authors: Rotte, Anand

Year: 2019

Venue: Journal of Experimental & Clinical Cancer Research

DOI: https://doi.org/10.1186/s13046-019-1259-z

Paper Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Li, Bo, Severson, Eric A., Pignon, Jean‐Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott J., Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley · 2016 · Genome biology · DOI

Full title: Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Authors: Li, Bo, Severson, Eric A., Pignon, Jean‐Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott J., Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley

Year: 2016

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-016-1028-7

Paper Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Álvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, María C., Pérez-Ruiz, Elísabeth, Melero, Ignacio, Berraondo, Pedro · 2019 · Cell Stress · DOI

Full title: Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Authors: Álvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, María C., Pérez-Ruiz, Elísabeth, Melero, Ignacio, Berraondo, Pedro

Year: 2019

Venue: Cell Stress

DOI: https://doi.org/10.15698/cst2019.07.193

Paper New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Hirsh, Vera · 2017 · OncoTargets and Therapy · DOI

Full title: New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Authors: Hirsh, Vera

Year: 2017

Venue: OncoTargets and Therapy

DOI: https://doi.org/10.2147/ott.s104177

Paper Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui · 2020 · OncoTargets and therapy · DOI

Full title: Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Authors: Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui

Year: 2020

Venue: OncoTargets and therapy

DOI: https://doi.org/10.2147/OTT.S235714

Paper Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng · 2021 · OncoTargets and Therapy · DOI

Full title: Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Authors: Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng

Year: 2021

Venue: OncoTargets and Therapy

DOI: https://doi.org/10.2147/ott.s269671

Paper Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma

Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi · 2022 · Frontiers in Chemistry · DOI

Full title: Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma

Authors: Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi

Year: 2022

Venue: Frontiers in Chemistry

DOI: https://doi.org/10.3389/fchem.2022.847621

Paper Combinatorial Approaches With Checkpoint Inhibitors to Enhance Anti-tumor Immunity

Seliger, Barbara · 2019 · Frontiers in Immunology · DOI

Full title: Combinatorial Approaches With Checkpoint Inhibitors to Enhance Anti-tumor Immunity

Authors: Seliger, Barbara

Year: 2019

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2019.00999

Paper Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping · 2020 · Frontiers in Immunology · DOI

Full title: Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Authors: Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping

Year: 2020

Venue: Frontiers in Immunology

DOI: https://doi.org/10.3389/fimmu.2020.01708

Paper Immunotherapy in Malignant Pleural Mesothelioma

Gooijer, Cornedine J. de; Borm, Frank J.; Scherpereel, Arnaud et al. · 2020 · Frontiers in Oncology · DOI

Full title: Immunotherapy in Malignant Pleural Mesothelioma

Authors: Gooijer, Cornedine J. de; Borm, Frank J.; Scherpereel, Arnaud; Baas, Paul

Year: 2020

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2020.00187

Paper Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan K., Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Clech, Marine Le, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina · 2020 · Frontiers in Oncology · DOI

Full title: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

Authors: Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan K., Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Clech, Marine Le, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina

Year: 2020

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2020.575737

Paper Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review

Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu · 2020 · Frontiers in Oncology · DOI

Full title: Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review

Authors: Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu

Year: 2020

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2020.602705

Paper Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei · 2021 · Frontiers in Oncology · DOI

Full title: Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Authors: Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.628124

Paper PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Xu, Ling, Liu, Lian, Yao, Danlin, Zeng, Xiangbo, Zhang, Yikai, Lai, Jing, Zhong, Jun, Zha, Xianfeng, Zheng, Runhui, Lu, Yuhong, Li, Minming, Jin, Zhenyi, Subramanyam, Sudheendra Hebbar, Chen, Shaohua, Huang, Xin, Li, Yangqiu · 2021 · Frontiers in Oncology · DOI

Full title: PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Authors: Xu, Ling, Liu, Lian, Yao, Danlin, Zeng, Xiangbo, Zhang, Yikai, Lai, Jing, Zhong, Jun, Zha, Xianfeng, Zheng, Runhui, Lu, Yuhong, Li, Minming, Jin, Zhenyi, Subramanyam, Sudheendra Hebbar, Chen, Shaohua, Huang, Xin, Li, Yangqiu

Year: 2021

Venue: Frontiers in Oncology

DOI: https://doi.org/10.3389/fonc.2021.686156

Paper Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund · 2021 · Cancers · DOI

Full title: Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Authors: Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13061430

Paper How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Martini, Giulia, Ciardiello, Davide, Paragliola, Fernando, Nacca, Valeria, Santaniello, W., Urraro, Fabrizio, Stanzione, Maria, Niosi, Marco, Dallio, Marcello, Federico, Alessandro, Selvaggi, Francesco, Corte, Carminia Maria Della, Napolitano, Stefania, Ciardiello, Fortunato, Martinelli, Erika · 2021 · Cancers · DOI

Full title: How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Authors: Martini, Giulia, Ciardiello, Davide, Paragliola, Fernando, Nacca, Valeria, Santaniello, W., Urraro, Fabrizio, Stanzione, Maria, Niosi, Marco, Dallio, Marcello, Federico, Alessandro, Selvaggi, Francesco, Corte, Carminia Maria Della, Napolitano, Stefania, Ciardiello, Fortunato, Martinelli, Erika

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13184719

Paper A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya · 2021 · Cancers · DOI

Full title: A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Authors: Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers14010203

Paper Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Bryant, Geoffrey, Wang, Lin, Mulholland, David J. · 2017 · International Journal of Molecular Sciences · DOI

Full title: Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Authors: Bryant, Geoffrey, Wang, Lin, Mulholland, David J.

Year: 2017

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms18071542

Paper Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo · 2020 · International Journal of Molecular Sciences · DOI

Full title: Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Authors: Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo

Year: 2020

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms21134691

Paper Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni · 2021 · International Journal of Molecular Sciences · DOI

Full title: Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Authors: Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22126309

Paper A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H. · 2020 · Current Oncology · DOI

Full title: A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Authors: Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H.

Year: 2020

Venue: Current Oncology

DOI: https://doi.org/10.3747/co.27.5223

Paper Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Li, Shan, Shen, Liangfang · 2020 · Journal of Cancer · DOI

Full title: Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Authors: Li, Shan, Shen, Liangfang

Year: 2020

Venue: Journal of Cancer

DOI: https://doi.org/10.7150/jca.44408

Thesis Part A - PD-1/PD-L1 blockade in cancer immunotherapy/ Part B - Evaluation of PD-1/PD-L1 immune checkpoint inhibitors in a luciferase-reporter cell-based assay

Peredo Aguilar, Maria Azucena · 2023 · University of Nottingham · DOI

Full title: Part A - PD-1/PD-L1 blockade in cancer immunotherapy/ Part B - Evaluation of PD-1/PD-L1 immune checkpoint inhibitors in a luciferase-reporter cell-based assay

Authors: Peredo Aguilar, Maria Azucena

Year: 2023

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/76035/1/MariaAzucenaAguilar_MResDissertation2023.pdf

Thesis Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP] et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Authors: Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP]; Dias, Queila Cristina; Pinheiro Fantinatti, Alexandra; Fávaro, Wagner José

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.3390/ani13121888

Thesis In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression

Yaegashi, Lygia Bertalha; Baldavira, Camila Machado; Prieto, Tabatha Gutierrez et al. · 2022 · Universidade Estadual Paulista (UNESP) · DOI

Full title: In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression

Authors: Yaegashi, Lygia Bertalha; Baldavira, Camila Machado; Prieto, Tabatha Gutierrez; Machado-Rugolo, Juliana [UNESP]; Velosa, Ana Paula Pereira; da Silveira, Lizandre Keren Ramos; Assato, Aline; Ab’Saber, Alexandre Muxfeldt; Falzoni, Roberto; Takagaki, Teresa; Silva, Pedro Leme; Teodoro, Walcy Rosolia; Capelozzi, Vera Luiza

Year: 2022

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.3389/fimmu.2021.714230

Thesis PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Melaiu, O; Mina, M; Chierici, M et al. · 2017 · UNSW Sydney · DOI

Full title: PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Authors: Melaiu, O; Mina, M; Chierici, M; Boldrini, R; Jurman, G; Romania, P; D'Alicandro, V; Benedetti, MC; Castellano, A; Liu, T ; https://orcid.org/0000-0001-6244-7316; Furlanello, C; Locatelli, F; Fruci, D

Year: 2017

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_44362

Thesis Major milestones in translational oncology.

Dragani, Tommaso A; Castells, Antoni; Kulasingam, Vathany et al. · 2016 · University of Cambridge · DOI

Full title: Major milestones in translational oncology.

Authors: Dragani, Tommaso A; Castells, Antoni; Kulasingam, Vathany; Diamandis, Eleftherios P; Earl, Helena; Iams, Wade T; Lovly, Christine M; Sedelaar, JP Michiel; Schalken, Jack A

Year: 2016

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/260591

Thesis Spotlight on landmark oncology trials: the latest evidence and novel trial designs.

Earl, Helena; Molica, Stefano; Rutkowski, Piotr · 2017 · University of Cambridge · DOI

Full title: Spotlight on landmark oncology trials: the latest evidence and novel trial designs.

Authors: Earl, Helena; Molica, Stefano; Rutkowski, Piotr

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/264598

Thesis Immunotherapy for Renal Cancer: Sequencing and Combinations

Stewart, GD; De Santis, M; Escudier, B et al. · 2017 · University of Cambridge · DOI

Full title: Immunotherapy for Renal Cancer: Sequencing and Combinations

Authors: Stewart, GD; De Santis, M; Escudier, B; Powles, T; Sonpavde, G

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/265376

Thesis Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Lim, SY; Lee, JH; Welsh, SJ et al. · 2017 · UNSW Sydney · DOI

Full title: Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Authors: Lim, SY; Lee, JH; Welsh, SJ; Ahn, SB; Breen, E; Khan, A ; https://orcid.org/0000-0002-5072-378X; Carlino, MS; Menzies, AM; Kefford, RF; Scolyer, RA; Long, GV; Rizos, H

Year: 2017

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_79785

Thesis Immune profiling of pediatric solid tumors

Terry, RL; https://orcid.org/0000-0002-6260-7372; Meyran, D et al. · 2020 · UNSW Sydney · DOI

Full title: Immune profiling of pediatric solid tumors

Authors: Terry, RL ; https://orcid.org/0000-0002-6260-7372; Meyran, D; Ziegler, DS ; https://orcid.org/0000-0001-7451-7916; Haber, M ; https://orcid.org/0000-0003-2036-8817; Ekert, PG ; https://orcid.org/0000-0002-2976-8617; Trapani, JA; Neeson, PJ

Year: 2020

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_80081

Thesis VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study.

Smyth, Elizabeth; Knödler, Maren; Giraut, Anne et al. · 2020 · University of Cambridge · DOI

Full title: VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study.

Authors: Smyth, Elizabeth; Knödler, Maren; Giraut, Anne; Mauer, Murielle; Nilsson, Magnus; Van Grieken, Nicole; Wagner, Anna Dorothea; Moehler, Markus; Lordick, Florian

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/303757

Thesis Medical treatment of renal cancer: new horizons.

Greef, Basma; Eisen, Tim · 2020 · University of Cambridge · DOI

Full title: Medical treatment of renal cancer: new horizons.

Authors: Greef, Basma; Eisen, Tim

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/303908

Thesis Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review.

Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth · 2022 · University of Cambridge · DOI

Full title: Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review.

Authors: Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/343973

Thesis 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr. et al. · 2024 · University of Cambridge · DOI

Full title: 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Authors: Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr.; Gallagher, Professor Ferdia; Menih, Ines Horvat, Dr.; Mossop, Helen, Dr.; Wason, Professor James; Easita, Farhana; Thomas, Martin, Dr.; Welsh, Sarah, Dr.; Mitchell, Mr Tom; Ursprung, Stephan, Dr.; O’Carrigan, Brent, Dr.

Year: 2024

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/372324

Thesis Enhancing Cancer Treatment through Combination Therapies

Mohajershojai, Tabassom · 2024 · Uppsala University · DOI

Full title: Enhancing Cancer Treatment through Combination Therapies

Authors: Mohajershojai, Tabassom

Year: 2024

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-530645

Thesis Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Iyer, Nivedha Srikanth · 2024 · University of California, San Diego (UCSD) · DOI

Full title: Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Authors: Iyer, Nivedha Srikanth

Year: 2024

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/5m579278

Thesis Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Wein, L; Luen, SJ; Savas, P et al. · 2020 · University of Melbourne · DOI

Full title: Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Authors: Wein, L; Luen, SJ; Savas, P; Salgado, R; Loi, S

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/255249

Thesis Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Meehan, K; Leslie, C; Lucas, M et al. · 2020 · University of Melbourne · DOI

Full title: Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Authors: Meehan, K; Leslie, C; Lucas, M; Jacques, A; Mirzai, B; Lim, J; Bulsara, M; Khan, Y; Wong, NC; Solomon, B; Sader, C; Friedland, P; Mir Arnau, G; Semple, T; Lim, AM

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/246366

Thesis An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Bottai, G; Raschioni, C; Losurdo, A et al. · 2020 · University of Melbourne · DOI

Full title: An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Authors: Bottai, G; Raschioni, C; Losurdo, A; Di Tommaso, L; Tinterri, C; Torrisi, R; Reis-Filho, JS; Roncalli, M; Sotiriou, C; Santoro, A; Mantovani, A; Loi, S; Santarpia, L

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/257795

Thesis Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Duarte, JDG; Parakh, S; Andrews, MC et al. · 2020 · University of Melbourne · DOI

Full title: Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Authors: Duarte, JDG; Parakh, S; Andrews, MC; Woods, K; Pasam, A; Tutuka, C; Ostrouska, S; Blackburn, JM; Behren, A; Cebon, J

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/256187

Thesis Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2021 · University of Melbourne · DOI

Full title: Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Authors: Bowyer, S; Prithviraj, P; Lorigan, P; Larkin, J; McArthur, G; Atkinson, V; Millward, M; Khou, M; Diem, S; Ramanujam, S; Kong, B; Liniker, E; Guminski, A; Parente, P; Andrews, MC; Parakh, S; Cebon, J; Long, GV; Carlino, MS; Klein, O

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/259450

Thesis Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Duchnowska, R; Peksa, R; Radecka, B et al. · 2021 · University of Melbourne · DOI

Full title: Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Authors: Duchnowska, R; Peksa, R; Radecka, B; Mandat, T; Trojanowski, T; Jarosz, B; Czartoryska-Arłukowicz, B; Olszewski, WP; Och, W; Kalinka-Warzocha, E; Kozłowski, W; Kowalczyk, A; Loi, S; Biernat, W; Jassem, J

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/260579

Thesis SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, A; Iravani, A; Lasocki, A et al. · 2021 · University of Melbourne · DOI

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, A; Iravani, A; Lasocki, A; Wallace, R; Weppler, A; Au-Yeung, G; Sachithanandan, N; Chiang, CY; Wentworth, J; Colman, PG; Kay, TW; Krishnamurthy, B; Sandhu, S

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/273859

Thesis Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Ascierto, PA; McArthur, GA · 2020 · University of Melbourne · DOI

Full title: Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Authors: Ascierto, PA; McArthur, GA

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/256879

Thesis Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2020 · University of Melbourne · DOI

Full title: Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/258389

Thesis Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Chew, HY; Dolcetti, R; Simpson, F · 2021 · University of Melbourne · DOI

Full title: Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Authors: Chew, HY; Dolcetti, R; Simpson, F

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/275929

Thesis Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Saleh, R; Taha, RZ; Toor, SM et al. · 2021 · University of Melbourne · DOI

Full title: Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Authors: Saleh, R; Taha, RZ; Toor, SM; Sasidharan Nair, V; Murshed, K; Khawar, M; Al-Dhaheri, M; Petkar, MA; Abu Nada, M; Elkord, E

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/277749

Thesis Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Saleh, R; Toor, SM; Al-Ali, D et al. · 2021 · University of Melbourne · DOI

Full title: Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Authors: Saleh, R; Toor, SM; Al-Ali, D; Sasidharan Nair, V; Elkord, E

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/277709

Thesis Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

Saleh, R; Toor, SM; Sasidharan Nair, V et al. · 2021 · University of Melbourne · DOI

Full title: Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

Authors: Saleh, R; Toor, SM; Sasidharan Nair, V; Elkord, E

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/277715

Thesis Real-world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab

Mohr, P; Ascierto, P; Arance, A et al. · 2021 · University of Melbourne · DOI

Full title: Real-world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab

Authors: Mohr, P; Ascierto, P; Arance, A; McArthur, G; Hernaez, A; Kaskel, P; Shinde, R; Stevinson, K

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/293838

Thesis Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Hilbers, ML; Dimitriou, F; Lau, P et al. · 2021 · University of Melbourne · DOI

Full title: Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Authors: Hilbers, ML; Dimitriou, F; Lau, P; Bhave, P; McArthur, GA; Zimmer, L; Kudura, K; Gérard, CL; Levesque, MP; Michielin, O; Dummer, R; Cheng, PF; Mangana, J

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/289654

Thesis Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Ahern, E; Solomon, BJ; Hui, R et al. · 2021 · University of Melbourne · DOI

Full title: Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Authors: Ahern, E; Solomon, BJ; Hui, R; Pavlakis, N; O'Byrne, K; Hughes, BGM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/287197

Thesis Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

Fennell, DA; Ewings, S; Ottensmeier, C et al. · 2022 · University of Melbourne · DOI

Full title: Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

Authors: Fennell, DA; Ewings, S; Ottensmeier, C; Califano, R; Hanna, GG; Hill, K; Danson, S; Steele, N; Nye, M; Johnson, L; Lord, J; Middleton, C; Szlosarek, P; Chan, S; Gaba, A; Darlison, L; Wells-Jordan, P; Richards, C; Poile, C; Lester, JF; Griffiths, G; Price, G; Shaw, P; Cave, J; Naik, J; Ford, A; Geldhart, T; Dancey, G; Papadatos, D; Polychronis, A; Jankowska, P; Scott, A; Gardiner, J; Cominos, M; Campbell, L; MacGregor, C; Mullholand, L; Chitnis, M; Dougherty, G

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/296717

Thesis Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Klein, O; Kee, D; Gao, B et al. · 2022 · University of Melbourne · DOI

Full title: Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Authors: Klein, O; Kee, D; Gao, B; Markman, B; Da Gama Duarte, J; Quigley, L; Jackett, L; Linklater, R; Strickland, A; Scott, C; Mileshkin, L; Palmer, J; Carlino, M; Behren, A; Cebon, J

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/296391

Thesis Immune checkpoint blockade in renal cell carcinoma

Rappold, PM; Silagy, AW; Kotecha, RR et al. · 2022 · University of Melbourne · DOI

Full title: Immune checkpoint blockade in renal cell carcinoma

Authors: Rappold, PM; Silagy, AW; Kotecha, RR; Hakimi, AA

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/298242

Thesis Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Lau, PKH; Feran, B; Smith, L et al. · 2022 · University of Melbourne · DOI

Full title: Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Authors: Lau, PKH; Feran, B; Smith, L; Lasocki, A; Molania, R; Smith, K; Weppler, A; Angel, C; Kee, D; Bhave, P; Lee, B; Young, RJ; Iravani, A; Yeang, HA; Vergara, IA; Kok, D; Drummond, K; Neeson, PJ; Sheppard, KE; Papenfuss, T; Solomon, BJ; Sandhu, S; McArthur, GA

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/296832

Thesis Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Klein, O; Senko, C; Carlino, MS et al. · 2022 · University of Melbourne · DOI

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Authors: Klein, O; Senko, C; Carlino, MS; Markman, B; Jackett, L; Gao, B; Lum, C; Kee, D; Behren, A; Palmer, J; Cebon, J

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/304665

Thesis Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion

Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Högler, Sandra (University of Veterinary Medicine Vienna) et al. · 2023 · University of Veterinary Medicine Vienna (Vetmeduni Vienna) · DOI

Full title: Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion

Authors: Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Högler, Sandra (University of Veterinary Medicine Vienna); Raigel, Martin (University of Veterinary Medicine Vienna); Kundi, Michael (Medical University of Vienna); Zielinski, Christoph C. (Wiener Privatklinik); Ede, Nicholas J. (Imugene Limited); Yavrom, Sharon (Imugene Limited); Garner-Spitzer, Erika (Medical University of Vienna); Kenner, Lukas (Medical University of Vienna); Lin, Diego Shih-Chieh (Taipei Veterans General Hospital); Chao, Yee (Taipei Veterans General Hospital)

Year: 2023

Venue: University of Veterinary Medicine Vienna (Vetmeduni Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:3001

Thesis Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Ferris, Robert L; Spanos, William C; Leidner, Rom et al. · 2021 · Utrecht University · DOI

Full title: Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Authors: Ferris, Robert L; Spanos, William C; Leidner, Rom; Gonçalves, Anthony; Martens, Uwe M; Kyi, Chrisann; Sharfman, William; Chung, Christine H; Devriese, Lot A; Gauthier, Helene; Chiosea, Simon I; Vujanovic, Lazar; Taube, Janis M; Stein, Julie E; Li, Jun; Li, Bin; Chen, Tian; Barrows, Adam; Topalian, Suzanne L

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/442886

Thesis Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M et al. · 2022 · Utrecht University · DOI

Full title: Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

Authors: van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M; Haanen, John B A G; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; de Groot, Jan-Willem B; Hospers, Geke A P; Kamphuis, Anna M; Kapiteijn, Ellen; May, Anne M; de Meza, Melissa M; Piersma, Djura; van Rijn, Rozemarijn; Stevense-den Boer, Marion A; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Blokx, Willeke A M; Wouters, Michel J M; Suijkerbuijk, Karijn P M

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/447350

Thesis Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

Lim, Michael; Weller, Michael; Idbaih, Ahmed et al. · 2022 · Utrecht University · DOI

Full title: Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

Authors: Lim, Michael; Weller, Michael; Idbaih, Ahmed; Steinbach, Joachim; Finocchiaro, Gaetano; Raval, Raju R; Ansstas, George; Baehring, Joachim; Taylor, Jennie W; Honnorat, Jerome; Petrecca, Kevin; De Vos, Filip; Wick, Antje; Sumrall, Ashley; Sahebjam, Solmaz; Mellinghoff, Ingo K; Kinoshita, Masashi; Roberts, Mustimbo; Slepetis, Ruta; Warad, Deepti; Leung, David; Lee, Michelle; Reardon, David A; Omuro, Antonio

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/446311

Thesis Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022 · Utrecht University · DOI

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Authors: Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien; Verheem, André; Cercel, Madalina; Van Hal, Susan; Boj, Sylvia F.; Borel Rinkes, Inne H.M.; Punt, Cornelis J.A.; Roodhart, Jeanine M.L.; Laoukili, Jamila; Koopman, Miriam; Spits, Hergen; Kranenburg, Onno

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2023 · Utrecht University · DOI

Full title: CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Authors: Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G; Leiner, Tim; Verhoeff, Joost J C; Arntz, Eran R A N; Troenokarso, Max F; Blokx, Willeke A M; Isgum, Ivana; de Wit, Geraldine A; van den Berkmortel, Franchette W P J; Boers-Sonderen, Marye J; Boomsma, Martijn F; van den Eertwegh, Fons J M; de Groot, Jan Willem B; Piersma, Djura; Vreugdenhil, Art; Westgeest, Hans M; Kapiteijn, Ellen; van Diest, Paul J; Pluim, Josien P W; de Jong, Pim A; Suijkerbuijk, Karijn P M; Veta, Mitko

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/448890

Thesis The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive et al. · 2024 · Utrecht University · DOI

Full title: The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Authors: Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive; Fox, Bernard; Ibrahim, Ramy; Sharma, Padmanee; Allison, James P.; Maio, Michele

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/454126

Thesis Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S. et al. · 2024 · Utrecht University · DOI

Full title: Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

Authors: van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S.; van Amsterdam, Wouter A.C.; van den Berkmortel, Franchette; Boers-Sonderen, Marye; de Groot, Jan Willem B.; Hospers, Geke A.P.; Kapiteijn, Ellen; Labots, Mariette; Piersma, Djura; Schrader, Anne M.R.; Vreugdenhil, Gerard; Westgeest, Hans; Veta, Mitko; Blokx, Willeke A.M.; van Diest, Paul J.; Suijkerbuijk, Karijn P.M.

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/454114

Thesis Immunosurveillance in clinical cancer management

Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M. et al. · 2024 · Utrecht University · DOI

Full title: Immunosurveillance in clinical cancer management

Authors: Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M.; Galluzzi, Lorenzo

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/454448

Thesis Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M. et al. · 2024 · Utrecht University · DOI

Full title: Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Authors: Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M.; Wolthuis, Esther K.; van Thienen, Johannes V.; van der Heijden, Michiel S.; Haanen, John B.A.G.; Beijnen, Jos H.; Huitema, Alwin D.R.

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/455323

Thesis Efficacy and safety in early-phase clinical trials for refractory colorectal cancer: A meta-analysis

Smabers, Lidwien P; Huismans, Maarten A; van Nieuwenhuijzen, Niels et al. · 2024 · Utrecht University · DOI

Full title: Efficacy and safety in early-phase clinical trials for refractory colorectal cancer: A meta-analysis

Authors: Smabers, Lidwien P; Huismans, Maarten A; van Nieuwenhuijzen, Niels; Minnema, Monique C; Kranenburg, Onno; Koopman, Miriam; Snippert, Hugo J G; May, Anne M; Roodhart, Jeanine M L

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/458345

Thesis Five latent factors underlie response to immunotherapy

Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A. et al. · 2024 · Utrecht University · DOI

Full title: Five latent factors underlie response to immunotherapy

Authors: Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A.; Batlle, Eduard; Carles, Joan; Cuppen, Edwin; Elez, Elena; Felip, Enriqueta; Gómez-Rey, Marina; Lo Giacco, Deborah; Martinez-Jimenez, Francisco; Muñoz-Couselo, Eva; Siu, Lillian L.; Tabernero, Josep; Vivancos, Ana; Muiños, Ferran; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/458268

Thesis Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors.

Nasca, Vincenzo; Zhao, Joseph; Ros, Javier et al. · 2025 · Utrecht University · DOI

Full title: Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors.

Authors: Nasca, Vincenzo; Zhao, Joseph; Ros, Javier; Lonardi, Sara; Zwart, Koen; Cohen, Romain; Fakih, Marwan; Jayachandran, Priya; Roodhart, Jeanine M L; Derksen, Jeroen; Intini, Rossana; Bergamo, Francesca; Mazzoli, Giacomo; Ghelardi, Filippo; Ligero, Marta; Jonnagaddala, Jitendra; Hawkins, Nicholas; Ward, Robyn L; Wankhede, Durgesh; Brenner, Hermann; Hoffmeister, Michael; Vitellaro, Marco; Salvatore, Lisa; Gallois, Claire; Laurent-Puig, Pierre; Cremolini, Chiara; Overman, Michael J; Taieb, Julien; Tougeron, David; Andre, Thierry; Kather, Jakob Nikolas; Sundar, Raghav; Carmona, Javier; Elez, Elena; Koopman, Miriam; Pietrantonio, Filippo

Year: 2025

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/460579

Thesis The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M. et al. · 2023 · Utrecht University · DOI

Full title: The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Authors: Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M.; Garbe, Claus; Gershenwald, Jeffrey E.; Hamid, Omid; Hauschild, Axel; Luke, Jason J.; Mehnert, Janice M.; Sosman, Jeffrey A.; Tawbi, Hussein A.; Mandalà, Mario; Testori, Alessandro; Caracò, Corrado; Osman, Iman; Puzanov, Igor

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/459059

Thesis Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William et al. · 2025 · Utrecht University · DOI

Full title: Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Authors: Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William; Meyer, Tim; Steven, Neil; Lao, Christopher D; Fariñas-Madrid, Lorena; Devriese, Lot A; Moore, Kathleen; Ferris, Robert L; Honma, Yoshitaka; Elias, Ileana; Srirangam, Anjaiah; Garnett-Benson, Charlie; Lee, Michelle; Nghiem, Paul

Year: 2025

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/460578

Thesis Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Authors: Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis; Szeto, Gregory; Tzeng, Alice; Zhu, Eric Franklin; Engreitz, Jesse Michael; Williams, Robert T.; Rakhra, Kavya; Zhang, Michael H; Rothschilds, Adrienne Marie; Kumari, Sudha; Kelly, Ryan Lewis; Kwan, Byron Hua; Abraham, Wuhbet; Hu, Kevin; Mehta, Naveen; Kauke, Monique Jacqueline; Suh, Heikyung; Lauffenburger, Douglas A; Wittrup, Karl Dane; Irvine, Darrell J

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/109826

Thesis Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Authors: Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A; Cintolo-Gonzalez, Jessica; Díaz-Martínez, Marta; Ohmura, Jacqueline; Mehta, Arnav; Chien, Isabel; Frederick, Dennie T; Cohen, Sonia; Plana, Deborah; Johnson, Douglas; Flaherty, Keith T; Sullivan, Ryan J; Kellis, Manolis; Boland, Genevieve M

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/132258.2

Thesis Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Regev, Aviv · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Authors: Regev, Aviv

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/125032

Thesis Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E. et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Authors: Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E.; Umeton, Renato; Albayrak, Adem; Subegdjo, Safiya J.; Johnson, Bruce E.; Nishino, Mizuki; Sholl, Lynette M.; Awad, Mark M.

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/128646

Thesis Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Spranger-Zimmermann, Stefani · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Authors: Spranger-Zimmermann, Stefani

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/126367

Thesis Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Authors: Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C; Kim, Albert E; Klein, Robert H; Nayyar, Naema; Navia, Andrew W; Kuter, Benjamin M; Kolb, Kellie E; Bihun, Ivanna; Mora, Joana L; Bertalan, Mia Solana; Shaw, Brian; White, Michael; Kaplan, Alexander; Stocking, Jackson H; Wadsworth, Marc H; Lee, Eudocia Q; Chukwueke, Ugonma; Wang, Nancy; Subramanian, Megha; Rotem, Denisse; Cahill, Daniel P; Adalsteinsson, Viktor A; Miller, Jeffrey W; Sullivan, Ryan J; Carter, Scott L; Brastianos, Priscilla K; Shalek, Alex K

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/141282

Thesis Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Lammers, Marshall · 2025 · University of California, Davis · DOI

Full title: Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Authors: Lammers, Marshall

Year: 2025

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/62w1z16d

Thesis Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Bhave, P; Pallan, L; Long, GV et al. · 2022 · University of Melbourne · DOI

Full title: Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Authors: Bhave, P; Pallan, L; Long, GV; Menzies, AM; Atkinson, V; Cohen, JV; Sullivan, RJ; Chiarion-Sileni, V; Nyakas, M; Kahler, K; Hauschild, A; Plummer, R; Trojaniello, C; Ascierto, PA; Zimmer, L; Schadendorf, D; Allayous, C; Lebbe, C; Maurichi, A; Santinami, M; Roy, S; Robert, C; Lesimple, T; Patel, S; Versluis, JM; Blank, CU; Khattak, A; Van der Westhuizen, A; Carlino, MS; Shackleton, M; Haydon, A

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/304521

Thesis Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma

Kennedy, OJ; Kicinski, M; Valpione, S et al. · 2022 · University of Melbourne · DOI

Full title: Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma

Authors: Kennedy, OJ; Kicinski, M; Valpione, S; Gandini, S; Suciu, S; Blank, CU; Long, GV; Atkinson, VG; Dalle, S; Haydon, AM; Meshcheryakov, A; Khattak, A; Carlino, MS; Sandhu, S; Larkin, J; Puig, S; Ascierto, PA; Rutkowski, P; Schadendorf, D; Koornstra, R; Hernandez-Aya, L; Di Giacomo, AM; van den Eertwegh, AJM; Grob, JJ; Gutzmer, R; Jamal, R; van Akkooi, ACJ; Robert, C; Eggermont, AMM; Lorigan, P; Mandala, M

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/322129

Thesis Insights into Cancer Immunotherapies: Recent Breakthroughs, Opportunities, and Challenges

Pappas, EG; Kershaw, MH; Slaney, CY · 2023 · University of Melbourne · DOI

Full title: Insights into Cancer Immunotherapies: Recent Breakthroughs, Opportunities, and Challenges

Authors: Pappas, EG; Kershaw, MH; Slaney, CY

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/327345

Thesis Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Bhave, P; Ahmed, T; Lo, SN et al. · 2022 · University of Melbourne · DOI

Full title: Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Authors: Bhave, P; Ahmed, T; Lo, SN; Shoushtari, A; Zaremba, A; Versluis, JM; Mangana, J; Weichenthal, M; Si, L; Lesimple, T; Robert, C; Trojanello, C; Wicky, A; Heywood, R; Tran, L; Batty, K; Dimitriou, F; Stansfeld, A; Allayous, C; Schwarze, JK; Mooradian, MJ; Klein, O; Mehmi, I; Roberts-Thomson, R; Maurichi, A; Yeoh, HL; Khattak, A; Zimmer, L; Blank, CU; Ramelyte, E; Kähler, KC; Roy, S; Ascierto, PA; Michielin, O; Lorigan, PC; Johnson, DB; Plummer, R; Lebbe, C; Neyns, B; Sullivan, R; Hamid, O; Santinami, M; McArthur, GA; Haydon, AM; Long, GV; Menzies, AM; Carlino, MS

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316921

Thesis IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Dunkel, IJ; Cohen, K; Foreman, NK et al. · 2022 · University of Melbourne · DOI

Full title: IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Authors: Dunkel, IJ; Cohen, K; Foreman, NK; Hargrave, D; Lassaletta, A; André, N; Hansford, JR; Hassall, T; Eyrich, M; Gururangan, S; Bartels, U; Gajjar, A; Howell, L; Warad, D; Pacius, M; Tam, R; Wang, Y; Zhu, L; Doz, F

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/318235

Thesis Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer

Augustine, T; John, P; Friedman, T et al. · 2023 · University of Melbourne · DOI

Full title: Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer

Authors: Augustine, T; John, P; Friedman, T; Jiffry, J; Guzik, H; Mannan, R; Gupta, R; Delano, C; Mariadason, JM; Zang, X; Maitra, R; Goel, S

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/335344

Thesis A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma

Voss, MH; Azad, AA; Hansen, AR et al. · 2023 · University of Melbourne · DOI

Full title: A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma

Authors: Voss, MH; Azad, AA; Hansen, AR; Gray, JE; Welsh, SJ; Song, X; Kuziora, M; Meinecke, L; Blando, J; Achour, I; Wang, Y; Walcott, FL; Oosting, SF

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/335610

Thesis First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

Kim, TW; Burris, HA; de Miguel Luken, MJ et al. · 2022 · University of Melbourne · DOI

Full title: First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

Authors: Kim, TW; Burris, HA; de Miguel Luken, MJ; Pishvaian, MJ; Bang, YJ; Gordon, M; Awada, A; Camidge, DR; Hodi, FS; McArthur, GA; Miller, WH; Cervantes, A; Chow, LQ; Lesokhin, AM; Rutten, A; Sznol, M; Rishipathak, D; Chen, SC; Stefanich, E; Pourmohamad, T; Anderson, M; Kim, J; Huseni, M; Rhee, I; Siu, LL

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/320417

Thesis Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.

Zhai, T; Wang, C; Xu, Y et al. · 2022 · University of Melbourne · DOI

Full title: Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.

Authors: Zhai, T; Wang, C; Xu, Y; Huang, W; Yuan, Z; Wang, T; Dai, S; Peng, S; Pang, T; Jiang, W; Huang, Y; Zou, Y; Xu, Y; Sun, J; Gong, X; Zhang, J; Tsun, A; Li, B; Miao, X

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/316255

Thesis 63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Reck, M; Regan, M; Carbone, DP et al. · 2024 · University of Melbourne · DOI

Full title: 63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Authors: Reck, M; Regan, M; Carbone, DP; Lu, S; John, T; Penrod, J; Li, J; Yuan, Y; Mahmood, J; Lee, A; Eccles, L; Ray, S; Paz-Ares, L

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/351905

Thesis Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Carbone, DP; Ciuleanu, TE; Schenker, M et al. · 2024 · University of Melbourne · DOI

Full title: Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Authors: Carbone, DP; Ciuleanu, TE; Schenker, M; Cobo, M; Bordenave, S; Juan-Vidal, O; Menezes, J; Reinmuth, N; Richardet, E; Cheng, Y; Mizutani, H; Felip, E; Zurawski, B; Alexandru, A; Paz-Ares, L; Lu, S; John, T; Zhang, X; Mahmood, J; Hu, N; De, T; Santi, I; Penrod, JR; Yuan, Y; Lee, A; Reck, M

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/352762

Thesis Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Zhang, J; Liang, W; Liang, H et al. · 2024 · University of Melbourne · DOI

Full title: Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Authors: Zhang, J; Liang, W; Liang, H; Wang, X; He, J

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/350365

Thesis A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Conduit, C; Davis, ID; Goh, JC et al. · 2024 · University of Melbourne · DOI

Full title: A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Authors: Conduit, C; Davis, ID; Goh, JC; Kichenadasse, G; Gurney, H; Harris, CA; Pook, D; Krieger, L; Parnis, F; Underhill, C; Adams, D; Roncolato, F; Joshua, A; Ferguson, T; Prithviraj, P; Morris, M; Harrison, M; Begbie, S; Hovey, E; George, M; Liow, EC; Link, EK; McJannett, M; Gedye, C

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/339980

Thesis A gut microbial signature for combination immune checkpoint blockade across cancer types

Gunjur, A; Shao, Y; Rozday, T et al. · 2024 · University of Melbourne · DOI

Full title: A gut microbial signature for combination immune checkpoint blockade across cancer types

Authors: Gunjur, A; Shao, Y; Rozday, T; Klein, O; Mu, A; Haak, BW; Markman, B; Kee, D; Carlino, MS; Underhill, C; Frentzas, S; Michael, M; Gao, B; Palmer, J; Cebon, J; Behren, A; Adams, DJ; Lawley, TD

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/353256

Thesis First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Hegewisch-Becker, S; Mendez, G; Chao, J et al. · 2025 · University of Melbourne · DOI

Full title: First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Authors: Hegewisch-Becker, S; Mendez, G; Chao, J; Nemecek, R; Feeney, K; Van Cutsem, E; Al-Batran, SE; Mansoor, W; Maisey, N; Pazo Cid, R; Burge, M; Perez-Callejo, D; Hipkin, RW; Mukherjee, S; Lei, M; Tang, H; Suryawanshi, S; Kelly, RJ; Tebbutt, NC

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/358332

Thesis A non-randomised open-label exploratory ‘window of opportunity’ study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer

Roth, S; Wilson, KC; Ramsay, RG et al. · 2025 · University of Melbourne · DOI

Full title: A non-randomised open-label exploratory ‘window of opportunity’ study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer

Authors: Roth, S; Wilson, KC; Ramsay, RG; Mitchell, C; Sampurno, S; Pham, TD; Huei Kong, JC; Wong, SQ; Heriot, AG; Deva, S; Burge, M; Sverdrup, C; Moller, AS; Kuryk, L; Eriksen, JA; Jaderberg, M; Zalcberg, JR; Michael, M

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/359449

Thesis Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · University of Melbourne · DOI

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/359086

Thesis Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · University of Melbourne · DOI

Full title: Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360026

Thesis Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander et al. · 2020 · University of Liverpool · DOI

Full title: Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Authors: Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander; Morrison, Ryan D; O’Neill Reising, Leslie; Ackermann, Bradley L; Fill, Jeff A; Schade, Andrew E; Gruver, Aaron M

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3091687/1/Analysis.pdf

Thesis Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Arriola, Edurne; Wheater, Matthew; Galea, Ian et al. · 2016 · University of Liverpool · DOI

Full title: Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Authors: Arriola, Edurne; Wheater, Matthew; Galea, Ian; Cross, Nadia; Maishman, Tom; Hamid, Debbie; Stanton, Louise; Cave, Judith; Geldart, Tom; Mulatero, Clive; Potter, Vannessa; Danson, Sarah; Woll, Pennella J; Griffiths, Richard; Nolan, Luke; Ottensmeier, Christian

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3169669/1/Outcome%20and%20Biomarker%20Analysis%20from%20a%20Multicenter%20Phase%202%20Study%20of%20Ipilimumab%20in%20Combination%20with%20Carboplatin%20and%20Etoposide%20.pdf

Thesis NOVEL MONO-, BI- AND TRI-SPECIFIC IMMUNOMODULATORY ANTIBODIES FOR CANCER THERAPY AND TOOLS FOR OTHER THERAPEUTIC AND DIAGNOSTIC APPLICATIONS

RAPUANO LEMBO, ROSA · 2025 · Università degli Studi di Milano (AIR) · DOI

Full title: NOVEL MONO-, BI- AND TRI-SPECIFIC IMMUNOMODULATORY ANTIBODIES FOR CANCER THERAPY AND TOOLS FOR OTHER THERAPEUTIC AND DIAGNOSTIC APPLICATIONS

Authors: RAPUANO LEMBO, ROSA

Year: 2025

Venue: Università degli Studi di Milano (AIR)

DOI: http://dx.doi.org/10.13130/rapuano-lembo-rosa_phd2025-12-19

Thesis The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Kuchroo, Juhi · 2020 · Harvard University - DASH · DOI

Full title: The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Authors: Kuchroo, Juhi

Year: 2020

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365910

Thesis Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Mangsbo, Sara · 2009 · Uppsala University · DOI

Full title: Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Authors: Mangsbo, Sara

Year: 2009

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110147

Thesis Antibody-based immunotherapy of cancer : From optimization to novel approaches

van Hooren, Luuk · 2018 · Uppsala University · DOI

Full title: Antibody-based immunotherapy of cancer : From optimization to novel approaches

Authors: van Hooren, Luuk

Year: 2018

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342799

Thesis A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Heinhuis, Kimberley Marga · 2020 · Utrecht University · DOI

Full title: A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Authors: Heinhuis, Kimberley Marga

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/400086

Thesis The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A et al. · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Authors: Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A; Pattada, Nimisha B; Bhutkar, Arjun; Eng, George; Mercer, Kim L; Garcia, Ana P; Lin, Lin; Rideout, William M; Hwang, William L; Schenkel, Jason M; Jaeger, Alex M; Bronson, Roderick T; Westcott, Peter MK; Hether, Tyler D; Divakar, Prajan; Reeves, Jason W; Deshpande, Vikram; Delorey, Toni; Phillips, Devan; Yilmaz, Omer H; Regev, Aviv; Jacks, Tyler

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/146821

Thesis Overall Survival of Elderly Patients with Non-Small Cell Lung Cancer Treated with Programmed Death-1 (PD-1) Inhibitors and Microbiome Altering Medications: A Retrospective Analysis Using the SEER-Medicare Database

Hughes, Valerie · 2023 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Overall Survival of Elderly Patients with Non-Small Cell Lung Cancer Treated with Programmed Death-1 (PD-1) Inhibitors and Microbiome Altering Medications: A Retrospective Analysis Using the SEER-Medicare Database

Authors: Hughes, Valerie

Year: 2023

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1692293042036511

Thesis Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Taggart, David John · 2016 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Authors: Taggart, David John

Year: 2016

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/16116/1/Thesis%20.pdf

Thesis Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

Chryplewicz, Agnieszka; Scotton, Julie; Tichet, Melanie et al. · 2022 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

Authors: Chryplewicz, Agnieszka; Scotton, Julie; Tichet, Melanie; Zomer, Anoek; Shchors, Ksenya; Joyce, Johanna A.; Homicsko, Krisztian; Hanahan, Douglas

Year: 2022

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/192476

Thesis Estimating Heterogeneity of Harm-Benefit Balance of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

Heyward, James Shivers · 2025 · Johns Hopkins University · DOI

Full title: Estimating Heterogeneity of Harm-Benefit Balance of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

Authors: Heyward, James Shivers

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70166

Thesis Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Ascierto, PA; Atkins, M; Bifulco, C et al. · 2021 · University of Melbourne · DOI

Full title: Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Authors: Ascierto, PA; Atkins, M; Bifulco, C; Botti, G; Cochran, A; Davies, M; Demaria, S; Dummer, R; Ferrone, S; Formenti, S; Gajewski, TF; Garbe, C; Khleif, S; Kiessling, R; Lo, R; Lorigan, P; Arthur, GM; Masucci, G; Melero, I; Mihm, M; Palmieri, G; Parmiani, G; Puzanov, I; Romero, P; Schilling, B; Seliger, B; Stroncek, D; Taube, J; Tomei, S; Zarour, HM; Testori, A; Wang, E; Galon, J; Ciliberto, G; Mozzillo, N; Marincola, FM; Thurin, M

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/262597

Thesis Relevance of blood-based biomarkers for prediction of response to chemotherapy and prognosis in lung cancer patients

Krüger, Kimberly · 2021 · Technical University of Munich (TUM) · DOI

Full title: Relevance of blood-based biomarkers for prediction of response to chemotherapy and prognosis in lung cancer patients

Authors: Krüger, Kimberly

Year: 2021

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1574259

Thesis Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Pühl, Miriam · 2024 · Freie Universität Berlin (Refubium) · DOI

Full title: Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Authors: Pühl, Miriam

Year: 2024

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/40924

Thesis TRIPLE IMMUNOTHERAPY TO OVERCOME IMMUNE EVASION BY TUMOR IN A MELANOMA MOUSE MODEL

Jallad, Mary-Ann · 2020 · American University of Beirut · DOI

Full title: TRIPLE IMMUNOTHERAPY TO OVERCOME IMMUNE EVASION BY TUMOR IN A MELANOMA MOUSE MODEL

Authors: Jallad, Mary-Ann

Year: 2020

Venue: American University of Beirut

DOI: http://hdl.handle.net/10938/22166

Thesis Immune Checkpoint Molecule Expression in Canine Lymphoma and Canine Reactive Lymphoid Hyperplasia

Clothier, Stacy Lauren · 2021 · Virginia Tech - VTechWorks · DOI

Full title: Immune Checkpoint Molecule Expression in Canine Lymphoma and Canine Reactive Lymphoid Hyperplasia

Authors: Clothier, Stacy Lauren

Year: 2021

Venue: Virginia Tech - VTechWorks

DOI: http://hdl.handle.net/10919/103200

Thesis Monitorización Inmunológica en Pacientes Tratados con Inhibidores de Puntos de Control Inmunitario: Identificación de Biomarcadores para la Predicción de Eventos Adversos Inmunomediados

Alserawan De Lamo, Leticia · 2024 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Monitorización Inmunológica en Pacientes Tratados con Inhibidores de Puntos de Control Inmunitario: Identificación de Biomarcadores para la Predicción de Eventos Adversos Inmunomediados

Authors: Alserawan De Lamo, Leticia

Year: 2024

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/692979

Thesis Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta · 2019 · Utrecht University · DOI

Full title: Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

Authors: van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta

Year: 2019

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/390030

Thesis Biomarkers in cancer immunotherapy

Schumacher, Ton N; Kesmir, Can; van Buuren, Marit M · 2015 · Utrecht University · DOI

Full title: Biomarkers in cancer immunotherapy

Authors: Schumacher, Ton N; Kesmir, Can; van Buuren, Marit M

Year: 2015

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/320977

Thesis Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Verheijden, Rik J; May, Anne M; Blank, Christian U et al. · 2020 · Utrecht University · DOI

Full title: Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Authors: Verheijden, Rik J; May, Anne M; Blank, Christian U; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; Boers-Sonderen, Marye J; van der Hoeven, Jacobus J M; Hospers, Geke A; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert; van der Veldt, Astrid Am; Vreugdenhil, Gerard; van Zeijl, Michiel C T; Wouters, Michel W J M; Haanen, John B A G; Kapiteijn, Ellen; Suijkerbuijk, Karijn Pm

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/396657

Thesis A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Arnaud-Coffin, P; Maillet, D; Gan, HK et al. · 2021 · University of Melbourne · DOI

Full title: A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Authors: Arnaud-Coffin, P; Maillet, D; Gan, HK; Stelmes, J-J; You, B; Dalle, S; Peron, J

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/285412

Thesis CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Wang, J; Li, X; Xiao, G et al. · 2024 · University of Melbourne · DOI

Full title: CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Authors: Wang, J; Li, X; Xiao, G; Desai, J; Frentzas, S; Wang, ZM; Xia, Y; Li, B

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/350752

Thesis Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Sandin, Linda · 2013 · Uppsala University · DOI

Full title: Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Authors: Sandin, Linda

Year: 2013

Venue: Uppsala University

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210080

Thesis Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Veinalde, Rūta · 2017 · Heidelberg University · DOI

Full title: Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Authors: Veinalde, Rūta

Year: 2017

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/23094/1/R.Veinalde_Thesis_print.pdf

Thesis Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022 · Utrecht University · DOI

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Wong, A; Callahan, J; Keyaerts, M et al. · 2020 · University of Melbourne · DOI

Full title: F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Authors: Wong, A; Callahan, J; Keyaerts, M; Neyns, B; Mangana, J; Aberle, S; Herschtal, A; Fullerton, S; Milne, D; Iravani, A; McArthur, GA; Hicks, RJ

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/246372

Thesis Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Verbrugge, I; Galli, M; Smyth, MJ et al. · 2021 · University of Melbourne · DOI

Full title: Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Authors: Verbrugge, I; Galli, M; Smyth, MJ; Johnstone, RW; Haynes, NM

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/265284

Thesis PHASE 1 STUDY OF AMG 160, A HALF-LIFE EXTENDED BITE® (BISPECIFIC T-CELL ENGAGER) THERAPY TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN, IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

Dorff, T; Rettig, M; Machiels, J-P et al. · 2021 · University of Melbourne · DOI

Full title: PHASE 1 STUDY OF AMG 160, A HALF-LIFE EXTENDED BITE® (BISPECIFIC T-CELL ENGAGER) THERAPY TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN, IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

Authors: Dorff, T; Rettig, M; Machiels, J-P; Lolkema, M; Autio, K; Greil, R; Rottey, S; Adra, N; Salvati, M; Poon, S; Tan, D; Jurida, G; Kouros-Mehr, H; Fizazi, K; Tran, B; Horvath, L

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/273969

Thesis IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

Giuffrida, L; Sek, K; Henderson, MA et al. · 2023 · University of Melbourne · DOI

Full title: IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

Authors: Giuffrida, L; Sek, K; Henderson, MA; House, IG; Lai, J; Chen, AXY; Todd, KL; Petley, EV; Mardiana, S; Todorovski, I; Gruber, E; Kelly, MJ; Solomon, BJ; Vervoort, SJ; Johnstone, RW; Parish, IA; Neeson, PJ; Kats, LM; Darcy, PK; Beavis, PA

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/331896

Thesis NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers

Brooker, RC; Schache, AG; Sacco, JJ · 2021 · University of Liverpool · DOI

Full title: NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers

Authors: Brooker, RC; Schache, AG; Sacco, JJ

Year: 2021

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3101657/1/Brooker%202020%20BJOMS_NICO%20short%20communication.pdf

Thesis Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Guillén, Noelia Carolina Talavera [UNESP] · 2023 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Authors: Guillén, Noelia Carolina Talavera [UNESP]

Year: 2023

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/239302

Thesis Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin et al. · 2018 · University of Cambridge · DOI

Full title: Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Authors: Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin; Joshi, Kroopa; Rosenthal, Rachel; Ghorani, Ehsan; Solomon, Isabelle; Lesko, Marta H; Ruef, Nora; Roddie, Claire; Henry, Jake Y; Spain, Lavinia; Ben Aissa, Assma; Georgiou, Andrew; Wong, Yien Ning Sophia; Smith, Myles; Strauss, Dirk; Hayes, Andrew; Nicol, David; O'Brien, Tim; Mårtensson, Linda; Ljungars, Anne; Teige, Ingrid; Frendéus, Björn; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia; Pule, Martin; Marafioti, Teresa; Gore, Martin; Larkin, James; Turajlic, Samra; Swanton, Charles; Peggs, Karl S; Quezada, Sergio A

Year: 2018

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/277642

Thesis Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.

Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak et al. · 2025 · University of Cambridge · DOI

Full title: Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.

Authors: Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak; Larkin, James; Powles, Tom; Stewart, Grant D; Albiges, Laurence; Bex, Axel; Choueiri, Toni K; Davis, Ian D; Eisen, Tim; Fielding, Alison; Gedye, Craig; Harrison, David J; Kaplan, Rick; Mulhere, Salena; Nathan, Paul; Patel, Grisma; Patel, Jay; Plant, Hannah; Ritchie, Alastair; Rush, Hannah; Shakeshaft, Clare; Stockler, Martin R; Suarez, Cristina; Thompson, Jemima; Thorogood, Nat; Venugopal, Balaji; Parmar, Mahesh KB

Year: 2025

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/378106

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2023

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· 2023

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· 2023

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· 2023

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· 2023

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· 2015

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· 2015

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· 2015

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· 2015

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· 2021

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· 2021

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· 2022

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Paper The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck cancer.

Dua, Divyanshu, Kelly, Charles, Kovarik, Josef, Iqbal, Muhammad Shahid · 2022 · Asia-Pacific journal of clinical oncology · DOI

Full title: The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck cancer.

Authors: Dua, Divyanshu, Kelly, Charles, Kovarik, Josef, Iqbal, Muhammad Shahid

Year: 2022

Venue: Asia-Pacific journal of clinical oncology

DOI: https://doi.org/10.1111/ajco.13583

Paper Combination with Stereotactic Body Radiotherapy Offers a Promising Strategy to Overcome Resistance to Immunotherapy in Advanced Renal Cell Cancer.

Sun, Xiaowen, Gan, Lu, Na, Aru, Ge, Lingling, Chen, Baoqing, Liu, Jiaming · 2019 · Journal of oncology · DOI

Full title: Combination with Stereotactic Body Radiotherapy Offers a Promising Strategy to Overcome Resistance to Immunotherapy in Advanced Renal Cell Cancer.

Authors: Sun, Xiaowen, Gan, Lu, Na, Aru, Ge, Lingling, Chen, Baoqing, Liu, Jiaming

Year: 2019

Venue: Journal of oncology

DOI: https://doi.org/10.1155/2019/1483406

Paper Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.

Kim, Wonwoo, Kim, Hyunkyung, Jang, Won Il, Kim, Mi Sook, Bae, Sun Hyun · 2025 · Current issues in molecular biology · DOI

Full title: Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.

Authors: Kim, Wonwoo, Kim, Hyunkyung, Jang, Won Il, Kim, Mi Sook, Bae, Sun Hyun

Year: 2025

Venue: Current issues in molecular biology

DOI: https://doi.org/10.3390/cimb48010020

Paper Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.

Chantharasamee, Jomjit, Adashek, Jacob J, Wong, Karlton, Eckardt, Mark A, Chmielowski, Bartosz, Dry, Sarah, Eilber, Fritz C, Singh, Arun S · 2021 · Current treatment options in oncology · DOI

Full title: Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.

Authors: Chantharasamee, Jomjit, Adashek, Jacob J, Wong, Karlton, Eckardt, Mark A, Chmielowski, Bartosz, Dry, Sarah, Eilber, Fritz C, Singh, Arun S

Year: 2021

Venue: Current treatment options in oncology

DOI: https://doi.org/10.1007/s11864-020-00806-z

Paper Impact of adding immune checkpoint inhibitors to standard therapies in non-small cell lung cancer: A systematic review of efficacy outcomes.

Correia, Ana Pinto, Marques, Adriana, Sepodes, Bruno, Torre, Carla, Rocha, João · 2026 · Critical reviews in oncology/hematology · DOI

Full title: Impact of adding immune checkpoint inhibitors to standard therapies in non-small cell lung cancer: A systematic review of efficacy outcomes.

Authors: Correia, Ana Pinto, Marques, Adriana, Sepodes, Bruno, Torre, Carla, Rocha, João

Year: 2026

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/j.critrevonc.2025.105098

Paper Abscopal Effects and Immunomodulation in Skin Cancer Therapy.

Nahm, William J, Sakunchotpanit, Goranit, Nambudiri, Vinod E · 2025 · American journal of clinical dermatology · DOI

Full title: Abscopal Effects and Immunomodulation in Skin Cancer Therapy.

Authors: Nahm, William J, Sakunchotpanit, Goranit, Nambudiri, Vinod E

Year: 2025

Venue: American journal of clinical dermatology

DOI: https://doi.org/10.1007/s40257-025-00943-x

Paper Combining radiotherapy and ipilimumab induces clinically relevant radiation-induced abscopal effects in metastatic melanoma patients: A systematic review.

Chicas-Sett, Rodolfo, Morales-Orue, Ignacio, Rodriguez-Abreu, Delvys, Lara-Jimenez, Pedro · 2018 · Clinical and translational radiation oncology · DOI

Full title: Combining radiotherapy and ipilimumab induces clinically relevant radiation-induced abscopal effects in metastatic melanoma patients: A systematic review.

Authors: Chicas-Sett, Rodolfo, Morales-Orue, Ignacio, Rodriguez-Abreu, Delvys, Lara-Jimenez, Pedro

Year: 2018

Venue: Clinical and translational radiation oncology

DOI: https://doi.org/10.1016/j.ctro.2017.12.004

Paper Combining conventional therapy with immunotherapy: A risky business?

Coosemans, A, Vankerckhoven, A, Baert, T, Boon, L, Ruts, H, Riva, M, Blagden, S, Delforge, M, Concin, N, Mirza, M R, Ledermann, J A, du Bois, A, Vergote, I · 2019 · European journal of cancer (Oxford, England : 1990) · DOI

Full title: Combining conventional therapy with immunotherapy: A risky business?

Authors: Coosemans, A, Vankerckhoven, A, Baert, T, Boon, L, Ruts, H, Riva, M, Blagden, S, Delforge, M, Concin, N, Mirza, M R, Ledermann, J A, du Bois, A, Vergote, I

Year: 2019

Venue: European journal of cancer (Oxford, England : 1990)

DOI: https://doi.org/10.1016/j.ejca.2019.02.014

Paper Personalized cancer vaccines and their integration with standard of care modalities.

Snäkä, Tiia, Friedlaender, Alex, Graciotti, Michele, Hernandez, Miriam, Rossier, Laetitia, Kirchner, Volker, Kandalaft, Lana · 2026 · Cancer treatment reviews · DOI

Full title: Personalized cancer vaccines and their integration with standard of care modalities.

Authors: Snäkä, Tiia, Friedlaender, Alex, Graciotti, Michele, Hernandez, Miriam, Rossier, Laetitia, Kirchner, Volker, Kandalaft, Lana

Year: 2026

Venue: Cancer treatment reviews

DOI: https://doi.org/10.1016/j.ctrv.2026.103095

Paper Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values.

Adashek, Jacob J, Genovese, Giannicola, Tannir, Nizar M, Msaouel, Pavlos · 2020 · Cancer treatment and research communications · DOI

Full title: Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values.

Authors: Adashek, Jacob J, Genovese, Giannicola, Tannir, Nizar M, Msaouel, Pavlos

Year: 2020

Venue: Cancer treatment and research communications

DOI: https://doi.org/10.1016/j.ctarc.2020.100166

Paper Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?

Robert, Lidia, Ribas, Antoni, Hu-Lieskovan, Siwen · 2016 · Seminars in immunology · DOI

Full title: Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?

Authors: Robert, Lidia, Ribas, Antoni, Hu-Lieskovan, Siwen

Year: 2016

Venue: Seminars in immunology

DOI: https://doi.org/10.1016/j.smim.2016.01.001

Paper Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors.

Timnik, Vincent R, Zoeschg, Andreas, Diederich, Sarah, Nefzger, Sophie M, Huang, Ziyi, Schmid, Nicole A, Giller, Maximilian, Steiger, Katja, Combs, Stephanie E, Kroemer, Guido, Schmid, Thomas E, Fischer, Julius C · 2025 · International journal of radiation oncology, biology, physics · DOI

Full title: Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors.

Authors: Timnik, Vincent R, Zoeschg, Andreas, Diederich, Sarah, Nefzger, Sophie M, Huang, Ziyi, Schmid, Nicole A, Giller, Maximilian, Steiger, Katja, Combs, Stephanie E, Kroemer, Guido, Schmid, Thomas E, Fischer, Julius C

Year: 2025

Venue: International journal of radiation oncology, biology, physics

DOI: https://doi.org/10.1016/j.ijrobp.2025.04.008

Paper Combining immunotherapies for the treatment of prostate cancer.

Redman, Jason M, Gulley, James L, Madan, Ravi A · 2017 · Urologic oncology · DOI

Full title: Combining immunotherapies for the treatment of prostate cancer.

Authors: Redman, Jason M, Gulley, James L, Madan, Ravi A

Year: 2017

Venue: Urologic oncology

DOI: https://doi.org/10.1016/j.urolonc.2017.09.024

Paper Enhancing efficacy of therapeutic vaccinations by combination with other modalities.

Gulley, James L, Madan, Ravi A, Arlen, Philip M · 2007 · Vaccine · DOI

Full title: Enhancing efficacy of therapeutic vaccinations by combination with other modalities.

Authors: Gulley, James L, Madan, Ravi A, Arlen, Philip M

Year: 2007

Venue: Vaccine

DOI: https://doi.org/10.1016/j.vaccine.2007.04.091

Paper Time to abandon single-site irradiation for inducing abscopal effects.

Brooks, Eric D, Chang, Joe Y · 2019 · Nature reviews. Clinical oncology · DOI

Full title: Time to abandon single-site irradiation for inducing abscopal effects.

Authors: Brooks, Eric D, Chang, Joe Y

Year: 2019

Venue: Nature reviews. Clinical oncology

DOI: https://doi.org/10.1038/s41571-018-0119-7

Paper Lung Cancer: Advances in Diagnosis and Management

Percy Lee, J. Goldman, J. Donington · 2020 · Seminars in Respiratory and Critical Care Medicine · DOI

Full title: Lung Cancer: Advances in Diagnosis and Management

Authors: Percy Lee, J. Goldman, J. Donington

Year: 2020

Venue: Seminars in Respiratory and Critical Care Medicine

DOI: https://doi.org/10.1055/s-0040-1709995

Paper Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?

Apetoh, L, Ladoire, S, Coukos, G, Ghiringhelli, F · 2015 · Annals of oncology : official journal of the European Society for Medical Oncology · DOI

Full title: Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?

Authors: Apetoh, L, Ladoire, S, Coukos, G, Ghiringhelli, F

Year: 2015

Venue: Annals of oncology : official journal of the European Society for Medical Oncology

DOI: https://doi.org/10.1093/annonc/mdv209

Paper Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34.

Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem · 2020 · Autophagy · DOI

Full title: Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34.

Authors: Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem

Year: 2020

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2020.1815439

Paper Pembrolizumab in mCRPC - Combination therapies as breakthrough to success?

Plas, Stefan, Pircher, Andreas, Heidegger, Isabel · 2023 · Current opinion in urology · DOI

Full title: Pembrolizumab in mCRPC - Combination therapies as breakthrough to success?

Authors: Plas, Stefan, Pircher, Andreas, Heidegger, Isabel

Year: 2023

Venue: Current opinion in urology

DOI: https://doi.org/10.1097/MOU.0000000000001121

Paper Getting personal in metastatic melanoma: neoantigen-based vaccines as a new therapeutic strategy.

D'Alise, Anna Morena, Scarselli, Elisa · 2023 · Current opinion in oncology · DOI

Full title: Getting personal in metastatic melanoma: neoantigen-based vaccines as a new therapeutic strategy.

Authors: D'Alise, Anna Morena, Scarselli, Elisa

Year: 2023

Venue: Current opinion in oncology

DOI: https://doi.org/10.1097/CCO.0000000000000923

Paper Targeted Therapies Combined With Immune Checkpoint Therapy.

Prieto, Peter A, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A · 2016 · Cancer journal (Sudbury, Mass.) · DOI

Full title: Targeted Therapies Combined With Immune Checkpoint Therapy.

Authors: Prieto, Peter A, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A

Year: 2016

Venue: Cancer journal (Sudbury, Mass.)

DOI: https://doi.org/10.1097/PPO.0000000000000182

Paper Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunotherapy relapsed melanoma with detected homologous recombination deficiency.

Khaddour, Karam, Ansstas, Michael, Ansstas, George · 2021 · Cold Spring Harbor molecular case studies · DOI

Full title: Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunotherapy relapsed melanoma with detected homologous recombination deficiency.

Authors: Khaddour, Karam, Ansstas, Michael, Ansstas, George

Year: 2021

Venue: Cold Spring Harbor molecular case studies

DOI: https://doi.org/10.1101/mcs.a006129

Paper Low-dose irradiation for reversing immunotherapy resistance: how to translate?

Ochoa-de-Olza, Maria, Bourhis, Jean, Coukos, George, Herrera, Fernanda G · 2022 · Journal for immunotherapy of cancer · DOI

Full title: Low-dose irradiation for reversing immunotherapy resistance: how to translate?

Authors: Ochoa-de-Olza, Maria, Bourhis, Jean, Coukos, George, Herrera, Fernanda G

Year: 2022

Venue: Journal for immunotherapy of cancer

DOI: https://doi.org/10.1136/jitc-2022-004939

Paper Radiotherapy for Melanoma: More than DNA Damage.

Rogers, Susanne J, Puric, Emsad, Eberle, Brigitte, Datta, Niloy R, Bodis, Stephan B · 2019 · Dermatology research and practice · DOI

Full title: Radiotherapy for Melanoma: More than DNA Damage.

Authors: Rogers, Susanne J, Puric, Emsad, Eberle, Brigitte, Datta, Niloy R, Bodis, Stephan B

Year: 2019

Venue: Dermatology research and practice

DOI: https://doi.org/10.1155/2019/9435389

Paper Current and Future Aspects of Immunotherapy for Esophageal and Gastric Malignancies.

De Mello, Ramon Andrade, Lordick, Florian, Muro, Kei, Janjigian, Yelena Y · 2019 · American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · DOI

Full title: Current and Future Aspects of Immunotherapy for Esophageal and Gastric Malignancies.

Authors: De Mello, Ramon Andrade, Lordick, Florian, Muro, Kei, Janjigian, Yelena Y

Year: 2019

Venue: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

DOI: https://doi.org/10.1200/EDBK_236699

Paper What’s new in melanoma? Combination!

P. Ascierto; F. Marincola; M. Atkins · 2015 · Journal of Translational Medicine · DOI

Full title: What’s new in melanoma? Combination!

Authors: P. Ascierto; F. Marincola; M. Atkins

Year: 2015

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-015-0582-1

Paper Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges.

Hu-Lieskovan, Siwen, Robert, Lidia, Homet Moreno, Blanca, Ribas, Antoni · 2014 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · DOI

Full title: Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges.

Authors: Hu-Lieskovan, Siwen, Robert, Lidia, Homet Moreno, Blanca, Ribas, Antoni

Year: 2014

Venue: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

DOI: https://doi.org/10.1200/JCO.2013.52.1377

Paper Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Series

J. Palmer, A. Suriawinata, Shaofeng Yan, D. A. Kerr, M. Afzal, Keisuke Shirai · 2023 · The American journal of case reports · DOI

Full title: Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Series

Authors: J. Palmer, A. Suriawinata, Shaofeng Yan, D. A. Kerr, M. Afzal, Keisuke Shirai

Year: 2023

Venue: The American journal of case reports

DOI: https://doi.org/10.12659/ajcr.938537

Paper Synergies of Targeting Angiogenesis and Immune Checkpoints in Cancer: From Mechanism to Clinical Applications.

Zhou, Shi, Zhang, Haijun · 2020 · Anti-cancer agents in medicinal chemistry · DOI

Full title: Synergies of Targeting Angiogenesis and Immune Checkpoints in Cancer: From Mechanism to Clinical Applications.

Authors: Zhou, Shi, Zhang, Haijun

Year: 2020

Venue: Anti-cancer agents in medicinal chemistry

DOI: https://doi.org/10.2174/1871520620666200207091653

Paper Combination approaches in NSCLC involving immune checkpoint inhibitors.

Arulananda, Surein, Rivalland, Gareth, John, Thomas · 2016 · Lung cancer management · DOI

Full title: Combination approaches in NSCLC involving immune checkpoint inhibitors.

Authors: Arulananda, Surein, Rivalland, Gareth, John, Thomas

Year: 2016

Venue: Lung cancer management

DOI: https://doi.org/10.2217/lmt-2016-0013

Paper Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists.

Xing, Daniel Tao, Khor, Richard, Gan, Hui, Wada, Morikatsu, Ermongkonchai, Tai, Ng, Sweet Ping · 2021 · Cancers · DOI

Full title: Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists.

Authors: Xing, Daniel Tao, Khor, Richard, Gan, Hui, Wada, Morikatsu, Ermongkonchai, Tai, Ng, Sweet Ping

Year: 2021

Venue: Cancers

DOI: https://doi.org/10.3390/cancers13225716

Paper Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities

A. Ganina, M. Askarov, Larissa Kozina, Madina Karimova, Y. Shayakhmetov, Perizat Mukhamedzhanova, A. Brimova, D. Berikbol, Elmira Chuvakova, L. Zaripova, Abay Baigenzhin · 2024 · Advances in Respiratory Medicine · DOI

Full title: Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities

Authors: A. Ganina, M. Askarov, Larissa Kozina, Madina Karimova, Y. Shayakhmetov, Perizat Mukhamedzhanova, A. Brimova, D. Berikbol, Elmira Chuvakova, L. Zaripova, Abay Baigenzhin

Year: 2024

Venue: Advances in Respiratory Medicine

DOI: https://doi.org/10.3390/arm92060045

Paper Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies.

D'Souza, Neil M, Fang, Penny, Logan, Jennifer, Yang, Jinzhong, Jiang, Wen, Li, Jing · 2016 · Frontiers in oncology · DOI

Full title: Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies.

Authors: D'Souza, Neil M, Fang, Penny, Logan, Jennifer, Yang, Jinzhong, Jiang, Wen, Li, Jing

Year: 2016

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2016.00212

Paper Public Adverse Event Data Insights into the Safety of Pembrolizumab in Melanoma Patients.

Schaefer, Anne, Sachpekidis, Christos, Diella, Francesca, Doerks, Anja, Kratz, Anne-Sophie, Meisel, Christian, Jackson, David B, Soldatos, Theodoros G · 2020 · Cancers · DOI

Full title: Public Adverse Event Data Insights into the Safety of Pembrolizumab in Melanoma Patients.

Authors: Schaefer, Anne, Sachpekidis, Christos, Diella, Francesca, Doerks, Anja, Kratz, Anne-Sophie, Meisel, Christian, Jackson, David B, Soldatos, Theodoros G

Year: 2020

Venue: Cancers

DOI: https://doi.org/10.3390/cancers12041008

Paper Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy.

Kobold, Sebastian, Pantelyushin, Stanislav, Rataj, Felicitas, Vom Berg, Johannes · 2018 · Frontiers in oncology · DOI

Full title: Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy.

Authors: Kobold, Sebastian, Pantelyushin, Stanislav, Rataj, Felicitas, Vom Berg, Johannes

Year: 2018

Venue: Frontiers in oncology

DOI: https://doi.org/10.3389/fonc.2018.00285

Paper Advances in mRNA-Based Melanoma Vaccines: A Narrative Review of Lipid Nanoparticle and Dendritic Cell Delivery Platforms

Connor K. Sisk, Laci M. Turner, Shafkat Meraj, Nabiha Yusuf · 2026 · Cells · DOI

Full title: Advances in mRNA-Based Melanoma Vaccines: A Narrative Review of Lipid Nanoparticle and Dendritic Cell Delivery Platforms

Authors: Connor K. Sisk, Laci M. Turner, Shafkat Meraj, Nabiha Yusuf

Year: 2026

Venue: Cells

DOI: https://doi.org/10.3390/cells15020099

Paper Modulation of CD8+ T Cell Responses by Radiotherapy-Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors.

Jeon, Seung Hyuck, Song, Changhoon, Eom, Keun-Yong, Kim, In Ah, Kim, Jae-Sung · 2023 · International journal of molecular sciences · DOI

Full title: Modulation of CD8+ T Cell Responses by Radiotherapy-Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors.

Authors: Jeon, Seung Hyuck, Song, Changhoon, Eom, Keun-Yong, Kim, In Ah, Kim, Jae-Sung

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms242316691

Paper Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.

Soldatos, Theodoros G, Dimitrakopoulou-Strauss, Antonia, Larribere, Lionel, Hassel, Jessica C, Sachpekidis, Christos · 2018 · Diagnostics (Basel, Switzerland) · DOI

Full title: Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.

Authors: Soldatos, Theodoros G, Dimitrakopoulou-Strauss, Antonia, Larribere, Lionel, Hassel, Jessica C, Sachpekidis, Christos

Year: 2018

Venue: Diagnostics (Basel, Switzerland)

DOI: https://doi.org/10.3390/diagnostics8040076

Paper Novel therapeutic strategies for non-small cell lung cancer: Combination therapies with immune checkpoint inhibitors (Review).

Ma, Shengyao, Hu, Ruixin, Xue, Xiaobin, Qu, Meihua, Sun, Guoping · 2025 · Oncology letters · DOI

Full title: Novel therapeutic strategies for non-small cell lung cancer: Combination therapies with immune checkpoint inhibitors (Review).

Authors: Ma, Shengyao, Hu, Ruixin, Xue, Xiaobin, Qu, Meihua, Sun, Guoping

Year: 2025

Venue: Oncology letters

DOI: https://doi.org/10.3892/ol.2025.15170

Paper HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

Yin, Lei, Li, Wenjia, Chen, Xuxiao, Wang, Ronghao, Zhang, Tao, Meng, Jialin, Zhao, Li, Li, Xu, Yin, Rui, Cheng, Bo, Yang, Huan · 2023 · Advanced Science · DOI

Full title: HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

Authors: Yin, Lei, Li, Wenjia, Chen, Xuxiao, Wang, Ronghao, Zhang, Tao, Meng, Jialin, Zhao, Li, Li, Xu, Yin, Rui, Cheng, Bo, Yang, Huan

Year: 2023

Venue: Advanced Science

DOI: https://doi.org/10.1002/advs.202206955

Paper Systemic treatments for metastatic cutaneous melanoma

Pasquali, Sandro, Hadjinicolaou, Andreas V., Chiarion‐Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone · 2018 · Cochrane Database of Systematic Reviews · DOI

Full title: Systemic treatments for metastatic cutaneous melanoma

Authors: Pasquali, Sandro, Hadjinicolaou, Andreas V., Chiarion‐Sileni, Vanna, Rossi, Carlo Riccardo, Mocellin, Simone

Year: 2018

Venue: Cochrane Database of Systematic Reviews

DOI: https://doi.org/10.1002/14651858.cd011123.pub2

Paper European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

Stratigos, Alexander, Garbe, Claus, Dessinioti, Clio, Lebbé, Célèste, Bataille, Véronique, Bastholt, Lars, Dréno, Brigitte, Fargnoli, Maria Concetta, Forsea, Ana‐Maria, Frenard, Cecille, Harwood, Catherine, Hauschild, Axel, Höeller, Christoph, Sekulović, Lidija Kandolf, Kaufmann, Roland, Kelleners-Smeets, Nicole W.J., Malvehy, Josep, Mármol, V. del, Middleton, Mark R., Moreno‐Ramírez, D., Pellecani, Giovanni, Peris, Ketty, Saïag, Philippe, Everdingen, M.H.J. van den Beuken-van, Vieira, Ricardo, Zalaudek, Iris, Eggermont, Alexander M.M., Grob, Jean-Jacques · 2020 · European Journal of Cancer · DOI

Full title: European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

Authors: Stratigos, Alexander, Garbe, Claus, Dessinioti, Clio, Lebbé, Célèste, Bataille, Véronique, Bastholt, Lars, Dréno, Brigitte, Fargnoli, Maria Concetta, Forsea, Ana‐Maria, Frenard, Cecille, Harwood, Catherine, Hauschild, Axel, Höeller, Christoph, Sekulović, Lidija Kandolf, Kaufmann, Roland, Kelleners-Smeets, Nicole W.J., Malvehy, Josep, Mármol, V. del, Middleton, Mark R., Moreno‐Ramírez, D., Pellecani, Giovanni, Peris, Ketty, Saïag, Philippe, Everdingen, M.H.J. van den Beuken-van, Vieira, Ricardo, Zalaudek, Iris, Eggermont, Alexander M.M., Grob, Jean-Jacques

Year: 2020

Venue: European Journal of Cancer

DOI: https://doi.org/10.1016/j.ejca.2020.01.008

Paper First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting by the Italian Association of Thoracic Oncology

Gridelli, Cesare, Peters, Solange, Mok, Tony, Forde, Patrick M., Reck, Martin, Attili, Ilaria, Marinis, Filippo de · 2021 · ESMO Open · DOI

Full title: First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting by the Italian Association of Thoracic Oncology

Authors: Gridelli, Cesare, Peters, Solange, Mok, Tony, Forde, Patrick M., Reck, Martin, Attili, Ilaria, Marinis, Filippo de

Year: 2021

Venue: ESMO Open

DOI: https://doi.org/10.1016/j.esmoop.2021.100355

Paper Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment

Passiglia, Francesco, Caglevic, Christian, Giovannetti, Elisa, Pinto, Joseph A., Manca, Paolo, Taverna, Simona, Listì, Angela, Gil‐Bazo, Ignacio, Raez, L., Russo, Antonio, Rolfo, Christian · 2018 · Seminars in Cancer Biology · DOI

Full title: Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment

Authors: Passiglia, Francesco, Caglevic, Christian, Giovannetti, Elisa, Pinto, Joseph A., Manca, Paolo, Taverna, Simona, Listì, Angela, Gil‐Bazo, Ignacio, Raez, L., Russo, Antonio, Rolfo, Christian

Year: 2018

Venue: Seminars in Cancer Biology

DOI: https://doi.org/10.1016/j.semcancer.2018.01.015

Paper Lung cancer: current therapies and new targeted treatments

Hirsch, Fred R., Scagliotti, Giorgio V., Mulshine, James L., Kwon, Regina, Curran, Walter J., Wu, Yi‐Long, Paz‐Ares, Luis · 2016 · The Lancet · DOI

Full title: Lung cancer: current therapies and new targeted treatments

Authors: Hirsch, Fred R., Scagliotti, Giorgio V., Mulshine, James L., Kwon, Regina, Curran, Walter J., Wu, Yi‐Long, Paz‐Ares, Luis

Year: 2016

Venue: The Lancet

DOI: https://doi.org/10.1016/s0140-6736(16)30958-8

Paper Advancing immunotherapy for early-stage triple-negative breast cancer

Cosimo, Serena Di · 2020 · The Lancet · DOI

Full title: Advancing immunotherapy for early-stage triple-negative breast cancer

Authors: Cosimo, Serena Di

Year: 2020

Venue: The Lancet

DOI: https://doi.org/10.1016/s0140-6736(20)31962-0

Paper Regulatory T cells in cancer immunotherapy

Tanaka, Atsushi, Sakaguchi, Shimon · 2016 · Cell Research · DOI

Full title: Regulatory T cells in cancer immunotherapy

Authors: Tanaka, Atsushi, Sakaguchi, Shimon

Year: 2016

Venue: Cell Research

DOI: https://doi.org/10.1038/cr.2016.151

Paper Targeting regulatory T cells in tumor immunotherapy

Smyth, Mark J., Ngiow, Shin Foong, Teng, Michele W.L. · 2014 · Immunology and Cell Biology · DOI

Full title: Targeting regulatory T cells in tumor immunotherapy

Authors: Smyth, Mark J., Ngiow, Shin Foong, Teng, Michele W.L.

Year: 2014

Venue: Immunology and Cell Biology

DOI: https://doi.org/10.1038/icb.2014.33

Paper Head and neck squamous cell carcinoma

Johnson, Daniel E., Burtness, Barbara, Leemans, C. René, Lui, Vivian Wai Yan, Bauman, Julie E., Grandis, Jennifer R. · 2020 · Nature Reviews Disease Primers · DOI

Full title: Head and neck squamous cell carcinoma

Authors: Johnson, Daniel E., Burtness, Barbara, Leemans, C. René, Lui, Vivian Wai Yan, Bauman, Julie E., Grandis, Jennifer R.

Year: 2020

Venue: Nature Reviews Disease Primers

DOI: https://doi.org/10.1038/s41572-020-00224-3

Paper Immunotherapy in colorectal cancer: rationale, challenges and potential

Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Díaz, Luis A. · 2019 · Nature Reviews Gastroenterology & Hepatology · DOI

Full title: Immunotherapy in colorectal cancer: rationale, challenges and potential

Authors: Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Díaz, Luis A.

Year: 2019

Venue: Nature Reviews Gastroenterology & Hepatology

DOI: https://doi.org/10.1038/s41575-019-0126-x

Paper Advances in immunotherapy for hepatocellular carcinoma

Sangro, Bruno, Sarobe, Pablo, Hervás‐Stubbs, Sandra, Melero, Ignacio · 2021 · Nature Reviews Gastroenterology & Hepatology · DOI

Full title: Advances in immunotherapy for hepatocellular carcinoma

Authors: Sangro, Bruno, Sarobe, Pablo, Hervás‐Stubbs, Sandra, Melero, Ignacio

Year: 2021

Venue: Nature Reviews Gastroenterology & Hepatology

DOI: https://doi.org/10.1038/s41575-021-00438-0

Paper A guide to cancer immunotherapy: from T cell basic science to clinical practice

Waldman, Alex D., Fritz, Jill M., Lenardo, Michael J. · 2020 · Nature reviews. Immunology · DOI

Full title: A guide to cancer immunotherapy: from T cell basic science to clinical practice

Authors: Waldman, Alex D., Fritz, Jill M., Lenardo, Michael J.

Year: 2020

Venue: Nature reviews. Immunology

DOI: https://doi.org/10.1038/s41577-020-0306-5

Paper Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer

Shin, Daniel Sanghoon, Park, Kevin, Garon, Edward B., Dubinett, Steven M. · 2022 · Seminars in Oncology · DOI

Full title: Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer

Authors: Shin, Daniel Sanghoon, Park, Kevin, Garon, Edward B., Dubinett, Steven M.

Year: 2022

Venue: Seminars in Oncology

DOI: https://doi.org/10.1053/j.seminoncol.2022.06.005

Paper Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma

Abou‐Alfa, Ghassan K., Lau, George, Kudo, Masatoshi, Chan, Stephen L., Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, Ostapenko, Yuriy, Yau, Thomas, Azevedo, Sérgio Jobim, Varela, Marı́a, Cheng, Ann‐Lii, Qin, Shukui, Galle, Peter R., Ali, Sajid, Marcovitz, Michelle, Makowsky, Mallory, He, Philip, Kurland, John F., Negro, Alejandra, Sangro, Bruno · 2022 · NEJM Evidence · DOI

Full title: Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma

Authors: Abou‐Alfa, Ghassan K., Lau, George, Kudo, Masatoshi, Chan, Stephen L., Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon‐Koo, Dao, Tu Van, Toni, Enrico N. De, Rimassa, Lorenza, Бредер, В. В., Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C., Mody, Kabir, Thungappa, Satheesh Chiradoni, Ostapenko, Yuriy, Yau, Thomas, Azevedo, Sérgio Jobim, Varela, Marı́a, Cheng, Ann‐Lii, Qin, Shukui, Galle, Peter R., Ali, Sajid, Marcovitz, Michelle, Makowsky, Mallory, He, Philip, Kurland, John F., Negro, Alejandra, Sangro, Bruno

Year: 2022

Venue: NEJM Evidence

DOI: https://doi.org/10.1056/evidoa2100070

Paper Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Wolchok, Jedd D., Chiarion‐Sileni, Vanna, González, René, Rutkowski, Piotr, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Wagstaff, John, Schadendorf, Dirk, Ferrucci, Pier Francesco, Smylie, Michael, Dummer, Reinhard, Hill, Andrew, Hogg, David, Haanen, John B.A.G., Carlino, Matteo S., Bechter, Oliver, Maio, Michele, Márquez‐Rodas, Iván, Guidoboni, Massimo, McArthur, Grant A., Lebbé, Célèste, Ascierto, Paolo A., Long, Georgina V., Cebon, Jonathan, Sosman, Jeffrey A., Postow, Michael A., Callahan, Margaret K., Walker, Damian, Rollin, Linda, Bhore, Rafia, Hodi, F. Stephen, Larkin, James · 2017 · New England Journal of Medicine · DOI

Full title: Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Authors: Wolchok, Jedd D., Chiarion‐Sileni, Vanna, González, René, Rutkowski, Piotr, Grob, Jean‐Jacques, Cowey, C. Lance, Lao, Christopher D., Wagstaff, John, Schadendorf, Dirk, Ferrucci, Pier Francesco, Smylie, Michael, Dummer, Reinhard, Hill, Andrew, Hogg, David, Haanen, John B.A.G., Carlino, Matteo S., Bechter, Oliver, Maio, Michele, Márquez‐Rodas, Iván, Guidoboni, Massimo, McArthur, Grant A., Lebbé, Célèste, Ascierto, Paolo A., Long, Georgina V., Cebon, Jonathan, Sosman, Jeffrey A., Postow, Michael A., Callahan, Margaret K., Walker, Damian, Rollin, Linda, Bhore, Rafia, Hodi, F. Stephen, Larkin, James

Year: 2017

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1709684

Paper Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

Motzer, Robert J., Tannir, Nizar M., McDermott, Ray, Frontera, Osvaldo Arén, Melichar, Bohuslav, Choueiri, Toni K., Plimack, Elizabeth R., Barthélémy, Philippe, Porta, Camillo, George, Saby, Powles, Thomas, Donskov, Frede, Neiman, Victoria, Kollmannsberger, Christian, Salman, Pamela, Gurney, Howard, Hawkins, Robert D., Ravaud, Alain, Grimm, Marc‐Oliver, Bracarda, Sergio, Barrios, Carlos H., Tomita, Yoshihiko, Castellano, Daniel, Rini, Brian I., Chen, Allen C., Mekan, Sabeen, McHenry, M. Brent, Wind‐Rotolo, Megan, Doan, Justin, Sharma, Padmanee, Hammers, Hans J., Escudier, Bernard · 2018 · New England Journal of Medicine · DOI

Full title: Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

Authors: Motzer, Robert J., Tannir, Nizar M., McDermott, Ray, Frontera, Osvaldo Arén, Melichar, Bohuslav, Choueiri, Toni K., Plimack, Elizabeth R., Barthélémy, Philippe, Porta, Camillo, George, Saby, Powles, Thomas, Donskov, Frede, Neiman, Victoria, Kollmannsberger, Christian, Salman, Pamela, Gurney, Howard, Hawkins, Robert D., Ravaud, Alain, Grimm, Marc‐Oliver, Bracarda, Sergio, Barrios, Carlos H., Tomita, Yoshihiko, Castellano, Daniel, Rini, Brian I., Chen, Allen C., Mekan, Sabeen, McHenry, M. Brent, Wind‐Rotolo, Megan, Doan, Justin, Sharma, Padmanee, Hammers, Hans J., Escudier, Bernard

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1712126

Paper Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

Socinski, Mark A., Jotte, Robert M., Cappuzzo, Federico, Orlandi, Francesco, Stroyakovskiy, Daniil, Nogami, Naoyuki, Rodríguez‐Abreu, Delvys, Moro‐Sibilot, Denis, Thomas, Christian A., Barlési, Fabrice, Finley, Gene Grant, Kelsch, Claudia, Lee, Anthony, Coleman, Shelley, Deng, Yu, Shen, Yijing, Kowanetz, Marcin, López-Chávez, Ariel, Sandler, Alan, Reck, Martin · 2018 · New England Journal of Medicine · DOI

Full title: Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

Authors: Socinski, Mark A., Jotte, Robert M., Cappuzzo, Federico, Orlandi, Francesco, Stroyakovskiy, Daniil, Nogami, Naoyuki, Rodríguez‐Abreu, Delvys, Moro‐Sibilot, Denis, Thomas, Christian A., Barlési, Fabrice, Finley, Gene Grant, Kelsch, Claudia, Lee, Anthony, Coleman, Shelley, Deng, Yu, Shen, Yijing, Kowanetz, Marcin, López-Chávez, Ariel, Sandler, Alan, Reck, Martin

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1716948

Paper Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

Tawbi, Hussein A., Forsyth, Peter, Algazi, Alain P., Hamid, Omid, Hodi, F. Stephen, Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl D., Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena, Tarhini, Ahmad A., Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim · 2018 · New England Journal of Medicine · DOI

Full title: Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

Authors: Tawbi, Hussein A., Forsyth, Peter, Algazi, Alain P., Hamid, Omid, Hodi, F. Stephen, Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl D., Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena, Tarhini, Ahmad A., Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim

Year: 2018

Venue: New England Journal of Medicine

DOI: https://doi.org/10.1056/nejmoa1805453

Paper Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

Peranzoni, Elisa, Lemoine, Jean, Vimeux, Lene, Feuillet, Vincent, Barrin, Sarah, Kantari‐Mimoun, Chahrazade, Bercovici, Nadège, Guérin, Marion V., Biton, Jérôme, Ouakrim, Hanane, Régnier, Fabienne, Lupo, Audrey, Alifano, Marco, Damotte, Diane, Donnadieu, Emmanuel · 2018 · Proceedings of the National Academy of Sciences · DOI

Full title: Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

Authors: Peranzoni, Elisa, Lemoine, Jean, Vimeux, Lene, Feuillet, Vincent, Barrin, Sarah, Kantari‐Mimoun, Chahrazade, Bercovici, Nadège, Guérin, Marion V., Biton, Jérôme, Ouakrim, Hanane, Régnier, Fabienne, Lupo, Audrey, Alifano, Marco, Damotte, Diane, Donnadieu, Emmanuel

Year: 2018

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1720948115

Paper Novel immunotherapy combinations for genitourinary cancers

Harthy, Munjid Al; Redman, Jason M.; Madan, Ravi A. · 2020 · Expert Opinion on Biological Therapy · DOI

Full title: Novel immunotherapy combinations for genitourinary cancers

Authors: Harthy, Munjid Al; Redman, Jason M.; Madan, Ravi A.

Year: 2020

Venue: Expert Opinion on Biological Therapy

DOI: https://doi.org/10.1080/14712598.2020.1713086

Paper Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns

Nikanjam, Mina, Patel, Harsh, Kurzrock, Razelle · 2017 · OncoImmunology · DOI

Full title: Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns

Authors: Nikanjam, Mina, Patel, Harsh, Kurzrock, Razelle

Year: 2017

Venue: OncoImmunology

DOI: https://doi.org/10.1080/2162402x.2017.1338997

Paper Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model

Kaumaya, Pravin T. P.; Guo, Linlin; Overholser, Jay et al. · 2020 · OncoImmunology · DOI

Full title: Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model

Authors: Kaumaya, Pravin T. P.; Guo, Linlin; Overholser, Jay; Penichet, Manuel L.; Bekaii‐Saab, Tanios

Year: 2020

Venue: OncoImmunology

DOI: https://doi.org/10.1080/2162402x.2020.1818437

Paper Immune checkpoint inhibitors in non-conventional histologies of renal-cell carcinoma

Bersanelli, Melissa, Rebuzzi, Sara Elena, Roviello, Giandomenico, Catalano, Martina, Brunelli, Matteo, Rizzo, Mimma · 2023 · Human Vaccines & Immunotherapeutics · DOI

Full title: Immune checkpoint inhibitors in non-conventional histologies of renal-cell carcinoma

Authors: Bersanelli, Melissa, Rebuzzi, Sara Elena, Roviello, Giandomenico, Catalano, Martina, Brunelli, Matteo, Rizzo, Mimma

Year: 2023

Venue: Human Vaccines & Immunotherapeutics

DOI: https://doi.org/10.1080/21645515.2023.2171672

Paper Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Peggs, Karl S., Quezada, Sergio A., Chambers, Cynthia A., Korman, Alan J., Allison, James P. · 2009 · The Journal of Experimental Medicine · DOI

Full title: Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Authors: Peggs, Karl S., Quezada, Sergio A., Chambers, Cynthia A., Korman, Alan J., Allison, James P.

Year: 2009

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20082492

Paper Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Sakuishi, Kaori, Apétoh, Lionel, Sullivan, Jenna M., Blazar, Bruce R., Kuchroo, Vijay K., Anderson, Ana C. · 2010 · The Journal of Experimental Medicine · DOI

Full title: Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Authors: Sakuishi, Kaori, Apétoh, Lionel, Sullivan, Jenna M., Blazar, Bruce R., Kuchroo, Vijay K., Anderson, Ana C.

Year: 2010

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20100643

Paper VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors

Voron, Thibault, Colussi, Orianne, Marcheteau, Elie, Pernot, Simon, Nizard, Mevyn, Pointet, Anne‐Laure, Latreche, Sabrina, Bergaya, Sonia, Benhamouda, Nadine, Tanchot, Corinne, Stockmann, Christian, Combe, Pierre, Berger, Anne, Zinzindohoué, Franck, Yagita∥, Hideo, Tartour, Éric, Taı̈eb, Julien, Terme, Magali · 2015 · The Journal of Experimental Medicine · DOI

Full title: VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors

Authors: Voron, Thibault, Colussi, Orianne, Marcheteau, Elie, Pernot, Simon, Nizard, Mevyn, Pointet, Anne‐Laure, Latreche, Sabrina, Bergaya, Sonia, Benhamouda, Nadine, Tanchot, Corinne, Stockmann, Christian, Combe, Pierre, Berger, Anne, Zinzindohoué, Franck, Yagita∥, Hideo, Tartour, Éric, Taı̈eb, Julien, Terme, Magali

Year: 2015

Venue: The Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20140559

Paper First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melanoma

Turajlic, Samra, Gore, Martin, Larkin, James · 2018 · Annals of Oncology · DOI

Full title: First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melanoma

Authors: Turajlic, Samra, Gore, Martin, Larkin, James

Year: 2018

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdy020

Paper Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Planchard, David, Popat, Sanjay, Kerr, Keith M., Novello, Silvia, Smit, Egbert F., Faivre‐Finn, Corinne, Mok, Tony, Reck, Martin, Schil, Paul E. Van, Hellmann, Matthew D., Peters, Solange · 2018 · Annals of Oncology · DOI

Full title: Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Authors: Planchard, David, Popat, Sanjay, Kerr, Keith M., Novello, Silvia, Smit, Egbert F., Faivre‐Finn, Corinne, Mok, Tony, Reck, Martin, Schil, Paul E. Van, Hellmann, Matthew D., Peters, Solange

Year: 2018

Venue: Annals of Oncology

DOI: https://doi.org/10.1093/annonc/mdy275

Paper Mechanisms of targeting cd28 by a signaling monoclonal antibody in acute and chronic allograft rejection1

Dong, Victor, Yuan, Xueli, Coito, Ana J., Waaga, Ana Maria, Sayegh, Mohamed H., Chandraker, Anil · 2002 · Transplantation · DOI

Full title: Mechanisms of targeting cd28 by a signaling monoclonal antibody in acute and chronic allograft rejection1

Authors: Dong, Victor, Yuan, Xueli, Coito, Ana J., Waaga, Ana Maria, Sayegh, Mohamed H., Chandraker, Anil

Year: 2002

Venue: Transplantation

DOI: https://doi.org/10.1097/00007890-200204270-00021

Paper Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic T-lymphocyte antigen-4 blockade in advanced melanoma

Agarwala, Sanjiv S. · 2010 · Melanoma Research · DOI

Full title: Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic T-lymphocyte antigen-4 blockade in advanced melanoma

Authors: Agarwala, Sanjiv S.

Year: 2010

Venue: Melanoma Research

DOI: https://doi.org/10.1097/cmr.0b013e328333bbc8

Paper Immune checkpoint blockade immunotherapy to activate anti‐tumour T ‐cell immunity

Ramsay, Alan G. · 2013 · British Journal of Haematology · DOI

Full title: Immune checkpoint blockade immunotherapy to activate anti‐tumour T ‐cell immunity

Authors: Ramsay, Alan G.

Year: 2013

Venue: British Journal of Haematology

DOI: https://doi.org/10.1111/bjh.12380

Paper Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine

Sato, Hiro, Jeggo, Penny A., Shibata, Atsushi · 2019 · Cancer Science · DOI

Full title: Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine

Authors: Sato, Hiro, Jeggo, Penny A., Shibata, Atsushi

Year: 2019

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.14197

Paper Dahuang Fuzi Baijiang decoction restricts progenitor to terminally exhausted T cell differentiation in colorectal cancer

Xu, Yihua, Wang, Hao, Wang, Tao, Chen, Chunhui, Sun, Ruibo, Yao, Wanyu, Ma, Ye, Zhang, Qingyuan, Wu, Liyi, Zeng, Shanmei, Sun, Xuegang · 2022 · Cancer Science · DOI

Full title: Dahuang Fuzi Baijiang decoction restricts progenitor to terminally exhausted T cell differentiation in colorectal cancer

Authors: Xu, Yihua, Wang, Hao, Wang, Tao, Chen, Chunhui, Sun, Ruibo, Yao, Wanyu, Ma, Ye, Zhang, Qingyuan, Wu, Liyi, Zeng, Shanmei, Sun, Xuegang

Year: 2022

Venue: Cancer Science

DOI: https://doi.org/10.1111/cas.15311

Paper Side effect management during immune checkpoint blockade using CTLA‐4 and PD‐1 antibodies for metastatic melanoma – an update

Kähler, Katharina C., Hassel, Jessica C., Heinzerling, Lucie, Loquai, Carmen, Thoms, Kai‐Martin, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf · 2020 · JDDG Journal der Deutschen Dermatologischen Gesellschaft · DOI

Full title: Side effect management during immune checkpoint blockade using CTLA‐4 and PD‐1 antibodies for metastatic melanoma – an update

Authors: Kähler, Katharina C., Hassel, Jessica C., Heinzerling, Lucie, Loquai, Carmen, Thoms, Kai‐Martin, Ugurel, Selma, Zimmer, Lisa, Gutzmer, Ralf

Year: 2020

Venue: JDDG Journal der Deutschen Dermatologischen Gesellschaft

DOI: https://doi.org/10.1111/ddg.14128

Paper Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Ju, Mingyi, Zhang, Jiaojiao, Deng, Zhuoyuan, Wei, Minjie, Ma, Lianghua, Chen, Ting, Lin, Zhao · 2024 · Journal for ImmunoTherapy of Cancer · DOI

Full title: Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Authors: Ju, Mingyi, Zhang, Jiaojiao, Deng, Zhuoyuan, Wei, Minjie, Ma, Lianghua, Chen, Ting, Lin, Zhao

Year: 2024

Venue: Journal for ImmunoTherapy of Cancer

DOI: https://doi.org/10.1136/jitc-2024-009345

Paper Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance

Bagchi, Sreya, Yuan, Robert, Engleman, Edgar G. · 2020 · Annual Review of Pathology Mechanisms of Disease · DOI

Full title: Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance

Authors: Bagchi, Sreya, Yuan, Robert, Engleman, Edgar G.

Year: 2020

Venue: Annual Review of Pathology Mechanisms of Disease

DOI: https://doi.org/10.1146/annurev-pathol-042020-042741

Paper Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

Herber, Donna L., Nagaraj, Srinivas, Djeu, Julie Y., Gabrilovich, Dmitry I. · 2007 · Cancer Research · DOI

Full title: Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

Authors: Herber, Donna L., Nagaraj, Srinivas, Djeu, Julie Y., Gabrilovich, Dmitry I.

Year: 2007

Venue: Cancer Research

DOI: https://doi.org/10.1158/0008-5472.can-07-0897

Paper Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Dewan, Md. Zahidunnabi, Galloway, Ashley E., Kawashima, Noriko, DeWyngaert, J. Keith, Babb, James S., Formenti, Silvia C., Demaria, Sandra · 2009 · Clinical Cancer Research · DOI

Full title: Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Authors: Dewan, Md. Zahidunnabi, Galloway, Ashley E., Kawashima, Noriko, DeWyngaert, J. Keith, Babb, James S., Formenti, Silvia C., Demaria, Sandra

Year: 2009

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-09-0265

Paper Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Hong, Dong‐Chun, Yang, Jing, Sun, Cong, Liu, Yuan-Tao, Shen, Lujun, Xu, Bu-Shu, Que, Yi, Xia, Xiaojun, Zhang, Xing · 2023 · Clinical Cancer Research · DOI

Full title: Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Authors: Hong, Dong‐Chun, Yang, Jing, Sun, Cong, Liu, Yuan-Tao, Shen, Lujun, Xu, Bu-Shu, Que, Yi, Xia, Xiaojun, Zhang, Xing

Year: 2023

Venue: Clinical Cancer Research

DOI: https://doi.org/10.1158/1078-0432.ccr-22-3567

Paper Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C., Guerriero, Jennifer L., Qi, Jun, Long, Henry W., Polyák, Kornélia · 2023 · Molecular Cancer Therapeutics · DOI

Full title: Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

Authors: Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C., Guerriero, Jennifer L., Qi, Jun, Long, Henry W., Polyák, Kornélia

Year: 2023

Venue: Molecular Cancer Therapeutics

DOI: https://doi.org/10.1158/1535-7163.mct-23-0303

Paper PD-L1 Expression in Triple-Negative Breast Cancer

Mittendorf, Elizabeth A., Philips, Anne V., Meric‐Bernstam, Funda, Qiao, Na, Wu, Yun, Harrington, Susan M., Su, Xiaoping, Wang, Ying, González-Angulo, Ana M., Akçakanat, Argun, Chawla, Akhil, Curran, Michael A., Hwu, Patrick, Sharma, Padmanee, Litton, Jennifer K., Molldrem, Jeffrey J., Alatrash, Gheath · 2014 · Cancer Immunology Research · DOI

Full title: PD-L1 Expression in Triple-Negative Breast Cancer

Authors: Mittendorf, Elizabeth A., Philips, Anne V., Meric‐Bernstam, Funda, Qiao, Na, Wu, Yun, Harrington, Susan M., Su, Xiaoping, Wang, Ying, González-Angulo, Ana M., Akçakanat, Argun, Chawla, Akhil, Curran, Michael A., Hwu, Patrick, Sharma, Padmanee, Litton, Jennifer K., Molldrem, Jeffrey J., Alatrash, Gheath

Year: 2014

Venue: Cancer Immunology Research

DOI: https://doi.org/10.1158/2326-6066.cir-13-0127

Paper PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis

Schneider, Stephanie, Potthast, Silke, Komminoth, Paul, Schwegler, Guido, Böhm, Steffen · 2017 · Case Reports in Oncology · DOI

Full title: PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis

Authors: Schneider, Stephanie, Potthast, Silke, Komminoth, Paul, Schwegler, Guido, Böhm, Steffen

Year: 2017

Venue: Case Reports in Oncology

DOI: https://doi.org/10.1159/000477162

Paper Immune Checkpoint Inhibitors in the Treatment of Patients with Neuroendocrine Neoplasia

Weber, Matthias M., Fottner, Christian · 2018 · Oncology Research and Treatment · DOI

Full title: Immune Checkpoint Inhibitors in the Treatment of Patients with Neuroendocrine Neoplasia

Authors: Weber, Matthias M., Fottner, Christian

Year: 2018

Venue: Oncology Research and Treatment

DOI: https://doi.org/10.1159/000488996

Paper Immune checkpoint inhibitors in advanced or metastatic mucosal melanoma: a systematic review

Li, Jiarui, Kan, Haoxuan, Zhao, Lin, Sun, Zhao, Bai, Chunmei · 2020 · Therapeutic Advances in Medical Oncology · DOI

Full title: Immune checkpoint inhibitors in advanced or metastatic mucosal melanoma: a systematic review

Authors: Li, Jiarui, Kan, Haoxuan, Zhao, Lin, Sun, Zhao, Bai, Chunmei

Year: 2020

Venue: Therapeutic Advances in Medical Oncology

DOI: https://doi.org/10.1177/1758835920922028

Paper Combinatorial approach to cancer immunotherapy: strength in numbers

Vilgelm, Anna E., Johnson, Douglas B., Richmond, Ann · 2016 · Journal of Leukocyte Biology · DOI

Full title: Combinatorial approach to cancer immunotherapy: strength in numbers

Authors: Vilgelm, Anna E., Johnson, Douglas B., Richmond, Ann

Year: 2016

Venue: Journal of Leukocyte Biology

DOI: https://doi.org/10.1189/jlb.5ri0116-013rr

Paper Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Brahmer, Julie R., Drake, Charles G., Wollner, Ira, Powderly, John D., Picus, Joel, Sharfman, William H., Stankevich, Elizabeth, Pons, Alice, Salay, Theresa M., McMiller, Tracee L., Gilson, Marta M., Wang, Changyu, Selby, Mark, Taube, Janis M., Anders, Robert A., Chen, Lieping, Korman, Alan J., Pardoll, Drew M., Lowy, Israel, Topalian, Suzanne L. · 2010 · Journal of Clinical Oncology · DOI

Full title: Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Authors: Brahmer, Julie R., Drake, Charles G., Wollner, Ira, Powderly, John D., Picus, Joel, Sharfman, William H., Stankevich, Elizabeth, Pons, Alice, Salay, Theresa M., McMiller, Tracee L., Gilson, Marta M., Wang, Changyu, Selby, Mark, Taube, Janis M., Anders, Robert A., Chen, Lieping, Korman, Alan J., Pardoll, Drew M., Lowy, Israel, Topalian, Suzanne L.

Year: 2010

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2009.26.7609

Paper Plinabulin, a novel small molecule clinical stage IO agent with anti-cancer activity, to prevent chemo-induced neutropenia and immune related AEs.

Mohanlal, Ramon, Lloyd, Ken, Huang, Lan · 2018 · Journal of Clinical Oncology · DOI

Full title: Plinabulin, a novel small molecule clinical stage IO agent with anti-cancer activity, to prevent chemo-induced neutropenia and immune related AEs.

Authors: Mohanlal, Ramon, Lloyd, Ken, Huang, Lan

Year: 2018

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2018.36.5_suppl.126

Paper Phase II study of ipilimumab, nivolumab, and panitumumab in patients with KRAS/NRAS/BRAF wild-type (WT) microsatellite stable (MSS) metastatic colorectal cancer (mCRC).

Lee, Michael Sangmin, Loehrer, Patrick J., Imanirad, Iman, Cohen, Stacey A., Ciombor, Kristen K., Moore, Dominic T., Carlson, Cheryl A., Sanoff, Hanna K., McRee, Autumn J. · 2021 · Journal of Clinical Oncology · DOI

Full title: Phase II study of ipilimumab, nivolumab, and panitumumab in patients with KRAS/NRAS/BRAF wild-type (WT) microsatellite stable (MSS) metastatic colorectal cancer (mCRC).

Authors: Lee, Michael Sangmin, Loehrer, Patrick J., Imanirad, Iman, Cohen, Stacey A., Ciombor, Kristen K., Moore, Dominic T., Carlson, Cheryl A., Sanoff, Hanna K., McRee, Autumn J.

Year: 2021

Venue: Journal of Clinical Oncology

DOI: https://doi.org/10.1200/jco.2021.39.3_suppl.7

Paper Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma

Qin, Qian, Nan, Xinyu, Miller, Tara, Fisher, Ronald E., Teh, Bin S., Pandita, Shruti, Farach, Andrew, Pingali, Sai Ravi, Pandita, Raj K., Butler, E. Brian, Pandita, Tej K., Iyer, Swaminathan P. · 2018 · Radiation Research · DOI

Full title: Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma

Authors: Qin, Qian, Nan, Xinyu, Miller, Tara, Fisher, Ronald E., Teh, Bin S., Pandita, Shruti, Farach, Andrew, Pingali, Sai Ravi, Pandita, Raj K., Butler, E. Brian, Pandita, Tej K., Iyer, Swaminathan P.

Year: 2018

Venue: Radiation Research

DOI: https://doi.org/10.1667/rr15048.1

Paper Non-small cell lung cancer: current treatment and future advances

Zappa, Cecilia, Mousa, Shaker A. · 2016 · Translational Lung Cancer Research · DOI

Full title: Non-small cell lung cancer: current treatment and future advances

Authors: Zappa, Cecilia, Mousa, Shaker A.

Year: 2016

Venue: Translational Lung Cancer Research

DOI: https://doi.org/10.21037/tlcr.2016.06.07

Paper Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy

Strudel, Martina, Festino, Lucia, Vanella, Vito, Beretta, Massimiliano, Marincola, Francesco M., Ascierto, Paolo A. · 2019 · Current Medicinal Chemistry · DOI

Full title: Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy

Authors: Strudel, Martina, Festino, Lucia, Vanella, Vito, Beretta, Massimiliano, Marincola, Francesco M., Ascierto, Paolo A.

Year: 2019

Venue: Current Medicinal Chemistry

DOI: https://doi.org/10.2174/0929867326666191205160007

Paper Immunotherapy Combinations for the Treatment of Patients with Solid Tumors

Bluthgen, M.V., Basté, Neus, Recondo, Gonzalo · 2020 · Future Oncology · DOI

Full title: Immunotherapy Combinations for the Treatment of Patients with Solid Tumors

Authors: Bluthgen, M.V., Basté, Neus, Recondo, Gonzalo

Year: 2020

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2020-0303

Paper MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer

Janjigian, Yelena Y., Cutsem, Eric Van, Muro, Kei, Wainberg, Zev A., Al‐Batran, Salah‐Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H., Negro, Alejandra, Tabernero, Josep · 2022 · Future Oncology · DOI

Full title: MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer

Authors: Janjigian, Yelena Y., Cutsem, Eric Van, Muro, Kei, Wainberg, Zev A., Al‐Batran, Salah‐Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H., Negro, Alejandra, Tabernero, Josep

Year: 2022

Venue: Future Oncology

DOI: https://doi.org/10.2217/fon-2022-0093

Paper Of Mice and Not Men: Differences between Mouse and Human Immunology

Mestas, Javier, Hughes, Christopher C.W. · 2004 · The Journal of Immunology · DOI

Full title: Of Mice and Not Men: Differences between Mouse and Human Immunology

Authors: Mestas, Javier, Hughes, Christopher C.W.

Year: 2004

Venue: The Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.172.5.2731

Paper Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: “A sharp sword”

Liang, Ping, Ye, Xin, Li, Xin · 2019 · Journal of Cancer Research and Therapeutics · DOI

Full title: Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: “A sharp sword”

Authors: Liang, Ping, Ye, Xin, Li, Xin

Year: 2019

Venue: Journal of Cancer Research and Therapeutics

DOI: https://doi.org/10.4103/jcrt.jcrt_910_18

Paper NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021

Ettinger, David S., Wood, Douglas E., Aisner, Dara L., Akerley, Wallace, Bauman, Jessica R., Bharat, Ankit, Bruno, Débora S., Chang, Joe Y., Chirieac, Lucian R., D’Amico, Thomas A., Dilling, Thomas J., Dowell, Jonathan E., Gettinger, Scott, Gubens, Matthew A., Hegde, Aparna, Hennon, Mark, Lackner, Rudy P., Lanuti, Michael, Leal, Ticiana, Lin, Jules, Loo, Billy W., Lovly, Christine M., Martins, Renato, Massarelli, Erminia, Morgensztern, Daniel, Ng, Thomas, Otterson, Gregory A., Patel, Sandip Pravin, Riely, Gregory J., Schild, Steven E., Shapiro, Theresa A., Singh, Aditi P., Stevenson, James, Tam, Alda L., Yanagawa, Jane, Yang, Stephen C., Gregory, Kristina M., Hughes, Miranda · 2021 · Journal of the National Comprehensive Cancer Network · DOI

Full title: NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021

Authors: Ettinger, David S., Wood, Douglas E., Aisner, Dara L., Akerley, Wallace, Bauman, Jessica R., Bharat, Ankit, Bruno, Débora S., Chang, Joe Y., Chirieac, Lucian R., D’Amico, Thomas A., Dilling, Thomas J., Dowell, Jonathan E., Gettinger, Scott, Gubens, Matthew A., Hegde, Aparna, Hennon, Mark, Lackner, Rudy P., Lanuti, Michael, Leal, Ticiana, Lin, Jules, Loo, Billy W., Lovly, Christine M., Martins, Renato, Massarelli, Erminia, Morgensztern, Daniel, Ng, Thomas, Otterson, Gregory A., Patel, Sandip Pravin, Riely, Gregory J., Schild, Steven E., Shapiro, Theresa A., Singh, Aditi P., Stevenson, James, Tam, Alda L., Yanagawa, Jane, Yang, Stephen C., Gregory, Kristina M., Hughes, Miranda

Year: 2021

Venue: Journal of the National Comprehensive Cancer Network

DOI: https://doi.org/10.6004/jnccn.2021.0013

Paper Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Ajani, Jaffer A., D’Amico, Thomas A., Bentrem, David J., Chao, Joseph, Cooke, David T., Corvera, Carlos U., Das, Prajnan, Enzinger, Peter C., Enzler, Thomas, Fanta, Paul T., Farjah, Farhood, Gerdes, Hans, Gibson, Michael K., Hochwald, Steven N., Hofstetter, Wayne L., Ilson, David H., Keswani, Rajesh N., Kim, Sunnie S. Y., Kleinberg, Lawrence, Klempner, Samuel J., Lacy, Jill, Ly, Quan P., Matkowskyj, Kristina A., McNamara, Michael J., Mulcahy, Mary F., Outlaw, Darryl, Park, Haeseong, Perry, Kyle A., Pimiento, José M., Poultsides, George A., Reznik, Scott I., Roses, Robert E., Strong, Vivian E., Su, Stacey, Wang, Hanlin L., Wiesner, Georgia L., Willett, Christopher G., Yakoub, Danny, Yoon, Harry H., McMillian, Nicole R., Pluchino, Lenora A. · 2022 · Journal of the National Comprehensive Cancer Network · DOI

Full title: Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Authors: Ajani, Jaffer A., D’Amico, Thomas A., Bentrem, David J., Chao, Joseph, Cooke, David T., Corvera, Carlos U., Das, Prajnan, Enzinger, Peter C., Enzler, Thomas, Fanta, Paul T., Farjah, Farhood, Gerdes, Hans, Gibson, Michael K., Hochwald, Steven N., Hofstetter, Wayne L., Ilson, David H., Keswani, Rajesh N., Kim, Sunnie S. Y., Kleinberg, Lawrence, Klempner, Samuel J., Lacy, Jill, Ly, Quan P., Matkowskyj, Kristina A., McNamara, Michael J., Mulcahy, Mary F., Outlaw, Darryl, Park, Haeseong, Perry, Kyle A., Pimiento, José M., Poultsides, George A., Reznik, Scott I., Roses, Robert E., Strong, Vivian E., Su, Stacey, Wang, Hanlin L., Wiesner, Georgia L., Willett, Christopher G., Yakoub, Danny, Yoon, Harry H., McMillian, Nicole R., Pluchino, Lenora A.

Year: 2022

Venue: Journal of the National Comprehensive Cancer Network

DOI: https://doi.org/10.6004/jnccn.2022.0008

Thesis Neoadjuvant Nivolumab for Patients With Resectable Merkel Cell Carcinoma in the CheckMate 358 Trial

Topalian, Suzanne L; Bhatia, Shailender; Amin, Asim et al. · 2020 · Utrecht University · DOI

Full title: Neoadjuvant Nivolumab for Patients With Resectable Merkel Cell Carcinoma in the CheckMate 358 Trial

Authors: Topalian, Suzanne L; Bhatia, Shailender; Amin, Asim; Kudchadkar, Ragini R; Sharfman, William H; Lebbé, Celeste; Delord, Jean-Pierre; Dunn, Lara A; Shinohara, Michi M; Kulikauskas, Rima; Chung, Christine H; Martens, Uwe M; Ferris, Robert L; Stein, Julie E; Engle, Elizabeth L; Devriese, Lot A; Lao, Christopher D; Gu, Junchen; Li, Bin; Chen, Tian; Barrows, Adam; Horvath, Andrea; Taube, Janis M; Nghiem, Paul

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439676

Thesis Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma

Theurich, S.; Rothschild, S. I.; Hoffmann, M. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma

Authors: Theurich, S.; Rothschild, S. I.; Hoffmann, M.; Fabri, M.; Sommer, A.; Garcia-Marquez, M.; Thelen, M.; Schill, C.; Merki, R.; Schmid, T.; Koeberle, D.; Zippelius, A.; Baues, C.; Mauch, C.; Tigges, C.; Kreuter, A.; Borggrefe, J.; von Bergwelt-Baildon, M.; Schlaak, M.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/33958

Thesis Preliminary phase 1 profile of BMS-986179, an anti-CD73 antibody, in

Lorenzen, S.; Siu, L. L.; Burris, H. et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: Preliminary phase 1 profile of BMS-986179, an anti-CD73 antibody, in

Authors: Lorenzen, S.;Siu, L. L.;Burris, H.;Le, D. T.;Hollebecque, A.;Steeghs, N.;Delord, J-P;Hilton, J.;Barnhart, B.;Sega, E.;Sanghavi, K.;Klippel, A.;Hedvat, C.;Hilt, E.;Donovan, M.;Gipson, A.;Basciano, P.;Postelnek, J.;Zhao, Y.;Perez, R. P.;Carvajal, R. D.

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1586475

Thesis Investigating The Potential of Focused Ultrasound Mediated Hyperthermia on Improving the Efficacy of Anti PD-L1 Blockade in Brain Cancer

Sridhar, Shwetha · 2025 · Georgia Institute of Technology · DOI

Full title: Investigating The Potential of Focused Ultrasound Mediated Hyperthermia on Improving the Efficacy of Anti PD-L1 Blockade in Brain Cancer

Authors: Sridhar, Shwetha

Year: 2025

Venue: Georgia Institute of Technology

DOI: https://hdl.handle.net/1853/77739

Thesis PKC ? Germline Variants and Genetic Deletion in Mice Augment Anti-Tumor Immunity Through Regulation of Myeloid Cells

Cron, Kyle Ryan · 2022 · University of Chicago - Knowledge@UChicago · DOI

Full title: PKC ? Germline Variants and Genetic Deletion in Mice Augment Anti-Tumor Immunity Through Regulation of Myeloid Cells

Authors: Cron, Kyle Ryan

Year: 2022

Venue: University of Chicago - Knowledge@UChicago

DOI: https://knowledge.uchicago.edu/record/4882/files/Table%20S5.xlsx

Thesis Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Authors: Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben; Rohrberg, Kristoffer; Reker Hadrup, Sine; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a2066594-9c4f-4789-98cd-954e4dedb11a

Thesis Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Authors: Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh; Granhøj, Joachim Stoltenborg; Borch, Troels Holz; Peeters, Marlies J.W.; Donia, Marco; Andersen, Mads Hald; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Svane, Inge Marie; Met, Özcan; id_orcid 0000-0002-3256-7592

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/dd214e21-2ea3-4190-9abd-0fde4c243316

Thesis Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis

Téglási, Vanda; Reiniger, Lilla; Fabian, Katalin et al. · 2017 · Technical University of Denmark (DTU) · DOI

Full title: Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis

Authors: Téglási, Vanda; Reiniger, Lilla; Fabian, Katalin; Pipek, Orsolya; Csala, Irén; Bagó, Attila G.; Várallyai, Péter; Vízkeleti, Laura; Rojkó, Lívia; Tímár, József; Dome, Balazs; Szallasi, Zoltan Imre; Swanton, Charles; Moldvay, Judit

Year: 2017

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/aad54ec5-cbe3-403a-8f87-8e808e7f7cc4

Thesis Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016

Ascierto, Paolo A.; Agarwala, Sanjiv S.; Ciliberto, Gennaro et al. · 2017 · University of Copenhagen · DOI

Full title: Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016

Authors: Ascierto, Paolo A.; Agarwala, Sanjiv S.; Ciliberto, Gennaro; Demaria, Sandra; Dummer, Reinhard; Duong, Connie P. M.; Ferrone, Soldano; Formenti, Silvia C.; Garbe, Claus; Halaban, Ruth; Khleif, Samir; Luke, Jason J.; Mir, Lluis M.; Overwijk, Willem W.; Postow, Michael; Puzanov, Igor; Sondel, Paul; Taube, Janis M.; Straten, Per Thor; Stroncek, David F.; Wargo, Jennifer A.; Zarour, Hassane; Thurin, Magdalena

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/d93e49f2-3e0a-4728-a5c7-b557d53a0ea0

Thesis Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel et al. · 2016 · Technical University of Denmark (DTU) · DOI

Full title: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Authors: McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel; Andersen, Sofie Ramskov; Lyngaa, Rikke Birgitte; Saini, Sunil Kumar; id_orcid 0000-0003-3382-9432; Jamal-Hanjani, Mariam; Wilson, Gareth A; Birkbak, Nicolai J.; Hiley, Crispin T; Watkins, Thomas B K; Shafi, Seema; Murugaesu, Nirupa; Mitter, Richard; Akarca, Ayse U; Linares, Joseph; Marafioti, Teresa; Henry, Jake Y; Van Allen, Eliezer M; Miao, Diana; Schilling, Bastian; Schadendorf, Dirk; Garraway, Levi A; Makarov, Vladimir; Rizvi, Naiyer A; Snyder, Alexandra; Hellmann, Matthew D; Merghoub, Taha; Wolchok, Jedd D; Shukla, Sachet A; Wu, Catherine J; Peggs, Karl S; Chan, Timothy A; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Quezada, Sergio A; Swanton, Charles

Year: 2016

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/c36e3271-a3d9-46b6-b0d1-d3537ae20249

Thesis Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna et al. · 2024 · Technical University of Denmark (DTU) · DOI

Full title: Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Authors: Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna; Borch, Annie; Hendriksen, Sille; Mundt, Filip; Pedersen, Vilde; Mann, Matthias; Christensen, Ib J.; Skjøth-Ramussen, Jane; Yde, Christina W.; Kristensen, Bjarne W.; Poulsen, Hans S.; Hasselbalch, Benedikte; Svane, Inge M.; Lassen, Ulrik; Hadrup, Sine R.; id_orcid 0000-0002-5937-4344

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/f4f16359-bd83-400f-9fb9-cc2e8d28b17f

Thesis Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Tardos, Elisa Catafal · 2024 · Technical University of Denmark (DTU) · DOI

Full title: Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Authors: Tardos, Elisa Catafal

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/c1afaaf9-c0a2-4ecd-9361-2f3b8d8c2788

Thesis Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors

Silva, Ana P. S.; Coelho, Priscila V.; Anazetti, Maristella et al. · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors

Authors: Silva, Ana P. S.; Coelho, Priscila V.; Anazetti, Maristella; Simioni, Patricia U. [UNESP]

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1080/21645515.2016.1249551

Thesis Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Zhou, Xiuman; Du, Jiangfeng; Wang, Hongfei et al. · 2020 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Authors: Zhou, Xiuman; Du, Jiangfeng; Wang, Hongfei; Chen, Chunxia; Jiao, Ling; Cheng, Xiangrui; Zhou, Xiaowen; Chen, Shaomeng; Gou, Shanshan; Zhao, Wenshan; Zhai, Wenjie; Chen, Junhui; Gao, Yanfeng

Year: 2020

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-106151

Thesis Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer

Parra, Edwin Roger; Jiang, Mei; Machado-Rugolo, Juliana et al. · 2021 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer

Authors: Parra, Edwin Roger; Jiang, Mei; Machado-Rugolo, Juliana; Yaegashi, Lygia Bertalha; Prieto, Tabatha; Farhat, Cecilia; Sa, Vanessa Karen de [UNESP]; Nagai, Maria Aparecida [UNESP]; Cordeiro de Lima, Vladmir Claudio; Takagaki, Tereza; Terra, Ricardo; Fabro, Alexandre Todorovic; Capelozzi, Vera Luiza

Year: 2021

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.5858/arpa.2019-0419-OA

Thesis The Resistance Mechanisms of Lung Cancer Immunotherapy

Wang, Fen; Wang, Shubin; Zhou, Qing · 2020 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: The Resistance Mechanisms of Lung Cancer Immunotherapy

Authors: Wang, Fen; Wang, Shubin; Zhou, Qing

Year: 2020

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-106731

Thesis Molecular underpinnings of immunotherapy in the treatment of hepatocellular carcinoma and surgical implications

Haber, Philipp · 2024 · Freie Universität Berlin (Refubium) · DOI

Full title: Molecular underpinnings of immunotherapy in the treatment of hepatocellular carcinoma and surgical implications

Authors: Haber, Philipp

Year: 2024

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/42537

Thesis Biomarkers of response and resistance to anti-PD1 immunotherapy in melanoma.

Gide, Tuba Nur · 2019 · University of Sydney · DOI

Full title: Biomarkers of response and resistance to anti-PD1 immunotherapy in melanoma.

Authors: Gide, Tuba Nur

Year: 2019

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/21200

Thesis Discovery of biomarkers in malignant pleural mesothelioma

Ahmadzada, Tamkin · 2022 · University of Sydney · DOI

Full title: Discovery of biomarkers in malignant pleural mesothelioma

Authors: Ahmadzada, Tamkin

Year: 2022

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/29563

Thesis Characteristics of tumor microenvironment and novel immunotherapeutic strategies for non-small cell lung cancer

Wang, Fen; Yang, Mingyi; Luo, Weichi et al. · 2022 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Characteristics of tumor microenvironment and novel immunotherapeutic strategies for non-small cell lung cancer

Authors: Wang, Fen; Yang, Mingyi; Luo, Weichi; Zhou, Qing

Year: 2022

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-122998

Thesis Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on the IL23/IFNg axis

Lo, J; Cozzetto, D; Madgwick, M et al. · 2023 · Imperial College London · DOI

Full title: Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on the IL23/IFNg axis

Authors: Lo, J; Cozzetto, D; Madgwick, M; Sieh, JYXS; Olbei, M; Alexander, JL; Blanco, J Miguens; Kudo, H; Ibraheim, H; Liu, Z; Seoane, R Castro; Goldin, R; Marchesi, J; Korcsmaros, T; Lord, G; Powell, N

Year: 2023

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000778573400132&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Efficacy and safety of frontline systemic therapy for advanced HCC: a network meta-analysis of landmark phase III trials

Fulgenzi, Claudia Angela Maria; Scheiner, Bernhard; Korolewicz, James et al. · 2023 · Imperial College London · DOI

Full title: Efficacy and safety of frontline systemic therapy for advanced HCC: a network meta-analysis of landmark phase III trials

Authors: Fulgenzi, Claudia Angela Maria; Scheiner, Bernhard; Korolewicz, James; Stikas, Charalampos-Vlasios; Gennari, Alessandra; Vincenzi, Bruno; Openshaw, Mark R; Silletta, Marianna; Pinter, Matthias; Cortellini, Alessio; Scotti, Lorenza; D'Alessio, Antonio; Pinato, David J

Year: 2023

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/37025943

Thesis Melanoma and immunotherapy bridge 2015: Naples, Italy. 1-5 December 2015

Nanda, Vashisht GY; Peng, Weiyi; Hwu, Patrick et al. · 2024 · Imperial College London · DOI

Full title: Melanoma and immunotherapy bridge 2015: Naples, Italy. 1-5 December 2015

Authors: Nanda, Vashisht GY; Peng, Weiyi; Hwu, Patrick; Davies, Michael A; Ciliberto, Gennaro; Fattore, Luigi; Malpicci, Debora; Aurisicchio, Luigi; Ascierto, Paolo Antonio; Croce, Carlo M; Mancini, Rita; Spranger, Stefani; Gajewski, Thomas F; Wang, Yangyang; Ferrone, Soldano; Vanpouille-Box, Claire; Wennerberg, Erik; Pilones, Karsten A; Formenti, Silvia C; Demaria, Sandra; Tang, Haidong; Wang, Yang; Fu, Yang-Xin; Dummer, Reinhard; Puzanov, Igor; Tarhini, Ahmad; Chauvin, Joe-Marc; Pagliano, Ornella; Fourcade, Julien; Sun, Zhaojun; Wang, Hong; Sanders, Cindy; Kirkwood, John M; Chen, Tseng-hui Timothy; Maurer, Mark; Korman, Alan J; Zarour, Hassane M; Stroncek, David F; Huber, Veronica; Rivoltini, Licia; Thurin, Magdalena; Rau, Tilman; Lugli, Alessandro; Pagès, Franck; Camarero, Jorge; Sancho, Arantxa; Jommi, Claudio; de Coaña, Yago Pico; Wolodarski, Maria; Yoshimoto, Yuya; Gentilcore, Giusy; Poschke, Isabel; Masucci, Giuseppe V; Hansson, Johan; Kiessling, Rolf; Scognamiglio, Giosuè; Sabbatino, Francesco; Marino, Federica Zito; Anniciello, Anna Maria; Cantile, Monica; Cerrone, Margherita; Scala, Stefania; D’alterio, Crescenzo; Ianaro, Angela; Cirin, Giuseppe; Liguori, Giuseppina; Bott, Gerardo; Chapman, Paul B; Robert, Caroline; Larkin, James; Haanen, John B; Ribas, Antoni; Hogg, David; Hamid, Omid; Testori, Alessandro; Lorigan, Paul; Sosman, Jeffrey A; Flaherty, Keith T; Yue, Huibin; Coleman, Shelley; Caro, Ivor; Hauschild, Axel; McArthur, Grant A; Sznol, Mario; Callahan, Margaret K; Kluger, Harriet; Postow, Michael A; Gordan, RuthAnn; Segal, Neil H; Rizvi, Naiyer A; Lesokhin, Alexander; Atkins, Michael B; Burke, Matthew M; Ralabate, Amanda; Rivera, Angel; Kronenberg, Stephanie A; Agunwamba, Blessing; Ruisi, Mary; Horak, Christine; Jiang, Joel; Wolchok, Jedd; Ascierto, Paolo A; Liszkay, Gabriella; Maio, Michele; Mandalà, Mario; Demidov, Lev; Stoyakovskiy, Daniil; Thomas, Luc; de la Cruz-Merino, Luis; Atkinson, Victoria; Dutriaux, Caroline; Garbe, Claus; Wongchenko, Matthew; Chang, Ilsung; Koralek, Daniel O; Rooney, Isabelle; Yan, Yibing; Dréno, Brigitte; Sullivan, Ryan; Patel, Manish; Hodi, Stephen; Amaria, Rodabe; Boasberg, Peter; Wallin, Jeffrey; He, Xian; Cha, Edward; Richie, Nicole; Ballinger, Marcus; Smith, David C; Bauer, Todd M; Wasser, Jeffrey S; Luke, Jason J; Balmanoukian, Ani S; Kaufman, David R; Zhao, Yufan; Maleski, Janet; Leopold, Lance; Gangadhar, Tara C; Long, Georgina V; Michielin, Olivier; VanderWalde, Ari; Andtbacka, Robert HI; Cebon, Jonathan; Fernandez, Eugenio; Malvehy, Josep; Olszanski, Anthony J; Gause, Christine; Chen, Lisa; Chou, Jeffrey; Stephen Hodi, F; Brady, Benjamin; Mortier, Laurent; Hassel, Jessica C; Rutkowski, Piotr; McNeil, Catriona; Kalinka-Warzocha, Ewa; Lebbé, Celeste; Ny, Lars; Chacon, Matias; Queirolo, Paola; Loquai, Carmen; Cheema, Parneet; Berrocal, Alfonso; Eizmendi, Karmele Mujika; Bar-Sela, Gil; Horak, Christine; Hardy, Helene; Weber, Jeffrey S; Grob, Jean-Jacques; Marquez-Rodas, Ivan; Schmidt, Henrik; Briscoe, Karen; Baurain, Jean-François; Wolchok, Jedd D; Pinto, Rosamaria; De Summa, Simona; Garrisi, Vito Michele; Strippoli, Sabino; Azzariti, Amalia; Guida, Gabriella; Guida, Michele; Tommasi, Stefania; Jacquelot, Nicolas; Enot, David; Flament, Caroline; Pitt, Jonathan M; Vimond, Nadège; Blattner, Carolin; Yamazaki, Takahiro; Roberti, Maria-Paula; Vetizou, Marie; Daillere, Romain; Poirier-Colame, Vichnou; la Semeraro, Michaë; Caignard, Anne; Slingluff, Craig L; Sallusto, Federica; Rusakiewicz, Sylvie; Weide, Benjamin; Marabelle, Aurélien; Kohrt, Holbrook; Dalle, Stéphane; Cavalcanti, Andréa; Kroemer, Guido; Di Giacomo, Anna Maria; Maio, Michaele; Wong, Phillip; Yuan, Jianda; Umansky, Viktor; Eggermont, Alexander; Zitvogel, Laurence; Anna, Passarelli; Marco, Tucci; Stefania, Stucci; Francesco, Mannavola; Mariaelena, Capone; Gabriele, Madonna; Antonio, Ascierto Paolo; Franco, Silvestris; Roberti, María Paula; Enot, David P; Semeraro, Michaela; Jégou, Sarah; Flores, Camila; Chen, Tseng-hui Timothy; Kwon, Byoung S; Anderson, Ana Carrizossa; Borg, Christophe; Aubin, François; Ayyoub, Maha; De Presbiteris, Anna Lisa; Cordaro, Fabiola Gilda; Camerlingo, Rosa; Fratangelo, Federica; Mozzillo, Nicola; Pirozzi, Giuseppe; Patriarca, Eduardo J; Caputo, Emilia; Motti, Maria Letizia; Falcon, Rosaria; Miceli, Roberta; Capone, Mariaelena; Madonna, Gabriele; Mallardo, Domenico; Carrier, Maria Vincenza; Panza, Elisabetta; De Cicco, Paola; Armogida, Chiara; Ercolano, Giuseppe; Botti, Gerardo; Cirino, Giuseppe; Sandru, Angela; Blank, Miri; Balatoni, Timea; Olasz, Judit; Farkas, Emil; Szollar, Andras; Savolt, Akos; Godeny, Maria; Csuka, Orsolya; Horvath, Szabolcs; Eles, Klara; Shoenfeld, Yehuda; Kasler, Miklos; Costantini, Susan; Capone, Francesca; Moradi, Farnaz; Berglund, Pontus; Leandersson, Karin; Linnskog, Rickard; Andersson, Tommy; Prasad, Chandra Prakash; Nigro, Cristiana Lo; Lattanzio, Laura; Wang, Hexiao; Proby, Charlotte; Syed, Nelofer; Occelli, Marcella; Cauchi, Carolina; Merlano, Marco; Harwood, Catherine; Thompson, Alastair; Crook, Tim; Bifulco, Katia; Ingangi, Vincenzo; Minopoli, Michele; Ragone, Concetta; Pessi, Antonello; Mannavola, Francesco; D’Oronzo, Stella; Felici, Claudia; Tucci, Marco; Doronzo, Antonio; Silvestris, Franco; Ferretta, Anna; Guida, Stefania; Maida, Imma; Cocco, Tiziana; Passarelli, Anna; Quaresmini, Davide; Franzese, Ornella; Palermo, Belinda; Di Donna, Cosmo; Sperduti, Isabella; Foddai, MariaLaura; Stabile, Helena; Gismondi, Angela; Santoni, Angela; Nisticò, Paola; Sponghini, Andrea P; Platini, Francesca; Marra, Elena; Rondonotti, David; Alabiso, Oscar; Fierro, Maria T; Savoia, Paola; Stratica, Florian; Quaglino, Pietro; Di Monta, Gianluca; Corrado, Caracò; Di Marzo, Massimiliano; Ugo, Marone; Di Cecilia, Maria Luisa; Nicola, Mozzillo; Fusciello, Celeste; Marra, Antonio; Guarrasi, Rosario; Baldi, Carlo; Russo, Rosa; Di Giulio, Giovanni; Faiola, Vincenzo; Zeppa, Pio; Pepe, Stefano; Gambale, Elisabetta; Carella, Consiglia; Di Paolo, Alessandra; De Tursi, Michele; Marra, Laura; De Murtas, Fara; Sorrentino, Valeria; Voinea, Silviu; Panaitescu, Eugenia; Bolovan, Madalina; Stanciu, Adina; Cinca, Sabin; Botti, Chiara; Aquino, Gabriella; Anniciello, Annamaria; Fortes, Cristina; Mastroeni, Simona; Caggiati, Alessio; Passarelli, Francesca; Zappalà, Alba; Capuano, Maria; Bono, Riccardo; Nudo, Maurizio; Marino, Claudia; Michelozzi, Paola; De Biasio, Valeria; Battarra, Vincenzo C; Formenti, Silvia; Ascierto, Maria Libera; McMiller, Tracee L; Berger, Alan E; Danilova, Ludmila; Anders, Robert A; Netto, George J; Xu, Haiying; Pritchard, Theresa S; Fan, Jinshui; Cheadle, Chris; Cope, Leslie; Drake, Charles G; Pardoll, Drew M; Taube, Janis M; Topalian, Suzanne L; Gnjatic, Sacha; Nataraj, Sarah; Imai, Naoko; Rahman, Adeeb; Jungbluth, Achim A; Pan, Linda; Venhaus, Ralph; Park, Andrew; Lehmann, Frédéric F; Lendvai, Nikoletta; Cohen, Adam D; Cho, Hearn J; Daniel, Speiser; Hirsh, Vera

Year: 2024

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/27461275

Thesis Validation of surrogate endpoints used in clinical trials of immune checkpoint inhibitors and targeted therapies in advanced cancers

Kok, Peey Sei · 2023 · University of Sydney · DOI

Full title: Validation of surrogate endpoints used in clinical trials of immune checkpoint inhibitors and targeted therapies in advanced cancers

Authors: Kok, Peey Sei

Year: 2023

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/31296

Thesis Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK

Ng, Kenrick; Metcalf, Rob; Sacco, Joseph et al. · 2024 · Imperial College London · DOI

Full title: Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK

Authors: Ng, Kenrick; Metcalf, Rob; Sacco, Joseph; Kong, Anthony; Wheeler, Graham; Forsyth, Sharon; Bhat, Reshma; Ward, Joseph; Ensell, Leah; Lowe, Helen; Spanswick, Victoria; Hartley, John; White, Laura; Lloyd-Dehler, Elizabeth; Forster, Martin

Year: 2024

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/38011968

Thesis Immunotherapy for metastatic non-small cell lung cancer: therapeutic advances and biomarkers

Russano, Marco; La Cava, Giulia; Cortellini, Alessio et al. · 2024 · Imperial College London · DOI

Full title: Immunotherapy for metastatic non-small cell lung cancer: therapeutic advances and biomarkers

Authors: Russano, Marco; La Cava, Giulia; Cortellini, Alessio; Citarella, Fabrizio; Galletti, Alessandro; Di Fazio, Giuseppina Rita; Santo, Valentina; Brunetti, Leonardo; Vendittelli, Alessia; Fioroni, Iacopo; Pantano, Francesco; Tonini, Giuseppe; Vincenzi, Bruno

Year: 2024

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000938342100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Clinical use of programmed cell death-1 (PD-1) and its ligand (PD-L1) expression as discriminatory and predictive markers in ovarian cancer

Chatterjee, J; Dai, W; Abd Aziz, NH et al. · 2017 · Imperial College London · DOI

Full title: Clinical use of programmed cell death-1 (PD-1) and its ligand (PD-L1) expression as discriminatory and predictive markers in ovarian cancer

Authors: Chatterjee, J; Dai, W; Abd Aziz, NH; Teo, PY; Wahba, J; Phelps, DL; Maine, CJ; Whilding, L; Dina, R; Trevisan, G; Flower, K; George, A; Ghaem-Maghami, S

Year: 2017

Venue: Imperial College London

DOI: http://www.ncbi.nlm.nih.gov/pubmed/27986748

Thesis Efficacy of PD-1 checkpoint inhibitor therapy in melanoma and beyond: are peripheral T cell phenotypes the key?

Flaherty, Katie R; Kucykowicz, Stephanie; Schroth, Johannes et al. · 2023 · Imperial College London · DOI

Full title: Efficacy of PD-1 checkpoint inhibitor therapy in melanoma and beyond: are peripheral T cell phenotypes the key?

Authors: Flaherty, Katie R; Kucykowicz, Stephanie; Schroth, Johannes; Traves, Will; Mincham, Kyle T; Finney, George E

Year: 2023

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/38020310

Thesis Challenges and opportunities in the clinical development of immune checkpoint inhibitors for hepatocellular carcinoma

Flynn, Michael J; Sayed, Anwar A; Sharma, Rohini et al. · 2018 · Imperial College London · DOI

Full title: Challenges and opportunities in the clinical development of immune checkpoint inhibitors for hepatocellular carcinoma

Authors: Flynn, Michael J; Sayed, Anwar A; Sharma, Rohini; Siddique, Abdul; Pinato, David J

Year: 2018

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/30382576

Thesis Clinical implications of heterogeniety in PD-L1 immuno-histochemical detection in hepatocellular carcinoma: the Blueprint-HCC study

Pinato, David; Mauri, F; Spina, P et al. · 2019 · Imperial College London · DOI

Full title: Clinical implications of heterogeniety in PD-L1 immuno-histochemical detection in hepatocellular carcinoma: the Blueprint-HCC study

Authors: Pinato, David; Mauri, F; Spina, P; Cain, O; Siddique, A; Goldin, R; Victor, Stephane; Pizio, C; Akarca, A; Boldorini, RL; Mazzucchelli, L; Black, J; Shetty, S; Marafioti, T; Sharma, R

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/69730

Thesis Gene of the month: lymphocyte-activation gene 3 (LAG-3)

Lythgoe, Mark P; Liu, Daniel Si Kit; Annels, Nicola E et al. · 2024 · Imperial College London · DOI

Full title: Gene of the month: lymphocyte-activation gene 3 (LAG-3)

Authors: Lythgoe, Mark P; Liu, Daniel Si Kit; Annels, Nicola E; Krell, Jonathan; Frampton, Adam Enver

Year: 2024

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000694654700002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis PD-L1.

Kythreotou, Anthousa; Siddique, Abdul; Mauri, Francesco A et al. · 2018 · Imperial College London · DOI

Full title: PD-L1.

Authors: Kythreotou, Anthousa; Siddique, Abdul; Mauri, Francesco A; Bower, Mark; Pinato, David J

Year: 2018

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/55570

Thesis Checkpoint inhibitors for malignant melanoma: a systematic review and meta-analysis

Karlsson, A; Saleh, SN · 2017 · Imperial College London · DOI

Full title: Checkpoint inhibitors for malignant melanoma: a systematic review and meta-analysis

Authors: Karlsson, A; Saleh, SN

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/44053

Thesis Patient selection for anti-PD-1/PD-L1 therapy in advanced non-small-cell lung cancer: implications for clinical practice

Califano, Raffaele; Lal, Rohit; Lewanski, Conrad et al. · 2018 · Imperial College London · DOI

Full title: Patient selection for anti-PD-1/PD-L1 therapy in advanced non-small-cell lung cancer: implications for clinical practice

Authors: Califano, Raffaele; Lal, Rohit; Lewanski, Conrad; Nicolson, Marianne C; Ottensmeier, Christian H; Popat, Sanjay; Hodgson, Matthew; Postmus, Pieter E

Year: 2018

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/29978725

Thesis Programmed death ligand 1 (PD-L1) expression influences the immune-tolerogenic microenvironment in antiretroviral therapy-refractory Kaposi's sarcoma: a pilot study

Mletzko, S; Pinato, DJ; Robey, RC et al. · 2017 · Imperial College London · DOI

Full title: Programmed death ligand 1 (PD-L1) expression influences the immune-tolerogenic microenvironment in antiretroviral therapy-refractory Kaposi's sarcoma: a pilot study

Authors: Mletzko, S; Pinato, DJ; Robey, RC; Pria, AD; Benson, P; Imami, N; Bower, M

Year: 2017

Venue: Imperial College London

DOI: https://www.tandfonline.com/doi/full/10.1080/2162402X.2017.1304337

Thesis Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi et al. · 2020 · Imperial College London · DOI

Full title: Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Authors: Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi; Lee, Steve Seung-Young; Williford, John-Michael; Yasui, Mariko; Abe, Hiroyuki; Potin, Lambert; Hosseinchi, Peyman; Fukunaga, Kazuto; Raczy, Michal M; Gray, Laura T; Mansurov, Aslan; Katsumata, Kiyomitsu; Fukayama, Masashi; Kron, Stephen J; Swartz, Melody A; Hubbell, Jeffrey A

Year: 2020

Venue: Imperial College London

DOI: https://stm.sciencemag.org/content/11/487/eaau3259/tab-pdf

Thesis Programmed cell death ligands expression drives immune tolerogenesis across the diverse subtypes of neuroendocrine tumours

Pinato, David J; Vallipuram, Anu; Evans, Joanne S et al. · 2020 · Imperial College London · DOI

Full title: Programmed cell death ligands expression drives immune tolerogenesis across the diverse subtypes of neuroendocrine tumours

Authors: Pinato, David J; Vallipuram, Anu; Evans, Joanne S; Wong, Clement; Zhang, Hua; Brown, Matthew; Dina, Roberto E; Trivedi, Pritesh; Akarca, Ayse U; Marafioti, Teresa; Mauri, Francesco A; Sharma, Rohini

Year: 2020

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/32097935

Thesis Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako et al. · 2020 · Imperial College London · DOI

Full title: Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Authors: Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako; Larsson, Hans M; Potin, Lambert; Hosseinchi, Peyman; Galliverti, Gabriele; Swartz, Melody A; Hubbell, Jeffrey A

Year: 2020

Venue: Imperial College London

DOI: https://stm.sciencemag.org/content/9/415/eaan0401

Thesis Systematic review with meta-analysis: effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced enterocolitis

Ibraheim, Hair; Powell, Nicholas · 2020 · Imperial College London · DOI

Full title: Systematic review with meta-analysis: effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced enterocolitis

Authors: Ibraheim, Hair; Powell, Nicholas

Year: 2020

Venue: Imperial College London

DOI: https://onlinelibrary.wiley.com/doi/full/10.1111/apt.15998

Thesis Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Natoli, Marina; Bonito, Nair; Robinson, James D et al. · 2020 · Imperial College London · DOI

Full title: Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Authors: Natoli, Marina; Bonito, Nair; Robinson, James D; Ghaem-Maghami, Sadaf; Mao, Yumeng

Year: 2020

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/32200422

Thesis Perspectives on the neoadjuvant use of immunotherapy in hepatocellular carcinoma

Pinato, David J; Fessas, Petros; Sapisochin, Gonzalo et al. · 2021 · Imperial College London · DOI

Full title: Perspectives on the neoadjuvant use of immunotherapy in hepatocellular carcinoma

Authors: Pinato, David J; Fessas, Petros; Sapisochin, Gonzalo; Marron, Thomas U

Year: 2021

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/33369758

Thesis Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy.

Pinato, David; Murray, Sam; Forner, A et al. · 2021 · Imperial College London · DOI

Full title: Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy.

Authors: Pinato, David; Murray, Sam; Forner, A; Kaneko, Takahiro; Fessas, P; Toniutto, P; Minguez, B; Cacciato, V; Avellini, C; Diaz, A; Boyton, R; Altmann, D; Goldin, R; Akarca, A; Marafioti, T; Mauri, F; Casagrande, E; Grillo, F; Giannini, E; Bhoori, S; Mazzaferro, V

Year: 2021

Venue: Imperial College London

DOI: https://jitc.bmj.com/content/9/9/e003311

Thesis First-line treatment options for PD-L1-negative non-small cell lung cancer: a Bayesian network meta-analysis

Peng, Ling; Liang, Wen-Hua; Mu, De-Guang et al. · 2021 · Imperial College London · DOI

Full title: First-line treatment options for PD-L1-negative non-small cell lung cancer: a Bayesian network meta-analysis

Authors: Peng, Ling; Liang, Wen-Hua; Mu, De-Guang; Xu, Song; Hong, Shao-Dong; Stebbing, Justin; Liang, Fei; Xia, Yang

Year: 2021

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/34249693

Thesis PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma

Pinato, David; Cortellini, Alessio; Sukumaran, Ajithkumar et al. · 2021 · Imperial College London · DOI

Full title: PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma

Authors: Pinato, David; Cortellini, Alessio; Sukumaran, Ajithkumar; Cole, tom; Pai, madhava; Habib, Nagy; Spalding, Duncan; Sodergren, Mikael; Martinez, Maria; Dhillon, Tony; Tait, Paul; Thomas, Robert; Ward, Caroline; Kocher, Hemant; Yip, Vincent; Slater, Sarah; Sharma, Rohini

Year: 2021

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/88610

Thesis Dual immune checkpoint blockade for non-small cell lung cancer patients with PD-L1 high expression: calling an end?

Peng, Ling; Stebbing, Justin; Liang, Fei et al. · 2021 · Imperial College London · DOI

Full title: Dual immune checkpoint blockade for non-small cell lung cancer patients with PD-L1 high expression: calling an end?

Authors: Peng, Ling; Stebbing, Justin; Liang, Fei; Xia, Yang

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000696884200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

Gide, TN; Quek, C; Menzies, AM et al. · 2019 · UNSW Sydney · DOI

Full title: Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

Authors: Gide, TN; Quek, C; Menzies, AM; Tasker, AT; Shang, P; Holst, J ; https://orcid.org/0000-0002-0377-9318; Madore, J; Lim, SY; Velickovic, R; Wongchenko, M; Yan, Y; Lo, S; Carlino, MS; Guminski, A; Saw, RPM; Pang, A ; https://orcid.org/0000-0003-1001-5102; McGuire, HM; Palendira, U; Thompson, JF; Rizos, H; Silva, IPD; Batten, M; Scolyer, RA; Long, GV; Wilmott, JS

Year: 2019

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_75518

Thesis IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients

Tallerico, R; Cristiani, CM; Staaf, E et al. · 2017 · University of Cambridge · DOI

Full title: IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients

Authors: Tallerico, R; Cristiani, CM; Staaf, E; Garofalo, C; Sottile, R; Capone, M; Pico de Coaña, Y; Madonna, G; Palella, E; Wolodarski, M; Carannante, V; Mallardo, D; Simeone, E; Grimaldi, AM; Johansson, S; Frumento, P; Gulletta, E; Anichini, A; Colucci, F; Ciliberto, G; Kiessling, R; Kärre, K; Ascierto, PA; Carbone, E

Year: 2017

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/265673

Thesis Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.

Au, Lewis; Hatipoglu, Emine; Robert de Massy, Marc et al. · 2021 · University of Cambridge · DOI

Full title: Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.

Authors: Au, Lewis; Hatipoglu, Emine; Robert de Massy, Marc; Litchfield, Kevin; Beattie, Gordon; Rowan, Andrew; Schnidrig, Desiree; Thompson, Rachael; Byrne, Fiona; Horswell, Stuart; Fotiadis, Nicos; Hazell, Steve; Nicol, David; Shepherd, Scott TC; Fendler, Annika; Mason, Robert; Del Rosario, Lyra; Edmonds, Kim; Lingard, Karla; Sarker, Sarah; Mangwende, Mary; Carlyle, Eleanor; Attig, Jan; Joshi, Kroopa; Uddin, Imran; Becker, Pablo D; Sunderland, Mariana Werner; Akarca, Ayse; Puccio, Ignazio; Yang, William W; Lund, Tom; Dhillon, Kim; Vasquez, Marcos Duran; Ghorani, Ehsan; Xu, Hang; Spencer, Charlotte; López, José I; Green, Anna; Mahadeva, Ula; Borg, Elaine; Mitchison, Miriam; Moore, David A; Proctor, Ian; Falzon, Mary; Pickering, Lisa; Furness, Andrew JS; Reading, James L; Salgado, Roberto; Marafioti, Teresa; Jamal-Hanjani, Mariam; PEACE Consortium; Kassiotis, George; Chain, Benny; Larkin, James; Swanton, Charles; Quezada, Sergio A; Turajlic, Samra; TRACERx Renal Consortium

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/330209

Thesis The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma.

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021 · University of Cambridge · DOI

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma.

Authors: Coen, Oliver; Corrie, Pippa; Marshall, Helen; Plummer, Ruth; Ottensmeier, Christian; Hook, Jane; Bell, Sue; Sagoo, Gurdeep S; Meads, David; Bestall, Janine; Velikova, Galina; Gallagher, Ferdia A; Smith, Alexandra; Howard, Helen; Mason, Ellen; Katona, Eszter; Silva, Shobha; Collinson, Michelle; Rodwell, Simon; Danson, Sarah

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/326323

Thesis Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander M.A. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Authors: Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander M.A.; Lieuwes, Natasja G.; Biemans, Rianne; Lieverse, Relinde I.Y.; Neri, Dario; id_orcid0000-0001-5234-7370; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J.; Lambin, Philippe

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/475414

Thesis Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells

Amaro, Adriana; Reggiani, Francesco; Fenoglio, Daniela et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells

Authors: Amaro, Adriana; Reggiani, Francesco; Fenoglio, Daniela; Gangemi, Rosaria; Tosi, Anna; Parodi, Alessia; Banelli, Barbara; Rigo, Valentina; Mastracci, Luca; Grillo, Federica; Cereghetti, Alessandra; Tastanova, Aizhan; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Sallustio, Fabio; Emionite, Laura; Daga, Antonio; Altosole, Tiziana; Filaci, Gilberto; Rosato, Antonio; Levesque, Mitchell; Maio, Michele; Pfeffer, Ulrich; EPigenetic Immune-oncology Consortium Airc (EPICA) consortium

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/606158

Thesis Promising potential of [Lu-177]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model

Guzik, Patrycja; Siwowska, Klaudia; Fang, Hsin-Yu et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Promising potential of [Lu-177]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model

Authors: Guzik, Patrycja; Siwowska, Klaudia; Fang, Hsin-Yu; Cohrs, Susan; Bernhardt, Peter; Schibli, Roger; Müller, Cristina

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/449947

Thesis Comprehensive statistical exploration of prognostic (Bio-)markers for responses to immune checkpoint inhibitor in patients with non-small cell lung cancer

Hiltbrunner, Stefanie; Spohn, Meta-Lina; Wechsler, Ramona et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Comprehensive statistical exploration of prognostic (Bio-)markers for responses to immune checkpoint inhibitor in patients with non-small cell lung cancer

Authors: Hiltbrunner, Stefanie; Spohn, Meta-Lina; Wechsler, Ramona; Akhounova, Dilara; Bankel, Lorenz; Kasser, Sabrina; Bihr, Svenja; Britschgi, Christian; Maathuis, Marloes H.; id_orcid0000-0002-3398-9893; Curioni-Fontecedro, Alessandra

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/522578

Thesis Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Nava Rodrigues, Daniel; Alimonti, Andrea; id_orcid0000-0002-9362-2313 et al. · 2018 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Authors: Nava Rodrigues, Daniel; Alimonti, Andrea; id_orcid0000-0002-9362-2313; et al.

Year: 2018

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/657225

Thesis Programmed death ligand 1 expression in early stage, resectable non-small cell lung cancer

D'Arcangelo, M; D'Incecco, A; Ligorio, C et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Programmed death ligand 1 expression in early stage, resectable non-small cell lung cancer

Authors: D'Arcangelo, M; D'Incecco, A; Ligorio, C; Damiani, S; Puccetti, M; Bravaccini, S; Terracciano, L; Bennati, C; Minuti, G; Vecchiarelli, S; Landi, L; Milesi, M; Meroni, A; Ravaioli, S; Tumedei, MM; Incarbone, M; Cappuzzo, F

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/41665

Thesis Modulating Innate Immunity via CD40-based Myeloid Targeting can Overcome anti-PD1 Therapy Resistance

Krykbaeva, Irina · 2022 · Yale University · DOI

Full title: Modulating Innate Immunity via CD40-based Myeloid Targeting can Overcome anti-PD1 Therapy Resistance

Authors: Krykbaeva, Irina

Year: 2022

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/615

Thesis Breast cancer biomarkers : dynamics during treatment and metastatic progression

Caroline Boman (18664618) · 2025 · Karolinska Institutet · DOI

Full title: Breast cancer biomarkers : dynamics during treatment and metastatic progression

Authors: Caroline Boman (18664618)

Year: 2025

Venue: Karolinska Institutet

DOI: oai:figshare.com:article/28623197

Thesis The effects of novel immune checkpoint inhibitors on melanoma patient's immune system

Kasanen, Henna · 2023 · University of Helsinki (HELDA) · DOI

Full title: The effects of novel immune checkpoint inhibitors on melanoma patient's immune system

Authors: Kasanen, Henna

Year: 2023

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/566654

Thesis The role and mechanisms of interleukin-9 in facilitating anticancer effect of immune checkpoint blockade in lung cancer animal model

Feng, Yuqian; 馮玉倩 · 2023 · University of Hong Kong · DOI

Full title: The role and mechanisms of interleukin-9 in facilitating anticancer effect of immune checkpoint blockade in lung cancer animal model

Authors: Feng, Yuqian; 馮玉倩

Year: 2023

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/327888

Thesis The use of immunotherapy in solid tumours : efficacy and toxicity

Wong, Sum-lung; 黃心龍 · 2018 · University of Hong Kong · DOI

Full title: The use of immunotherapy in solid tumours : efficacy and toxicity

Authors: Wong, Sum-lung; 黃心龍

Year: 2018

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/252496

Thesis Predictive values of peripheral blood biomarkers for atezolizumab in combination with bevacizumab, carboplatin and pemetrexed therapy in EGFR-mutant metastatic non-small cell lung cancer patients

Tsang, Ka Chun; 曾加駿 · 2022 · University of Hong Kong · DOI

Full title: Predictive values of peripheral blood biomarkers for atezolizumab in combination with bevacizumab, carboplatin and pemetrexed therapy in EGFR-mutant metastatic non-small cell lung cancer patients

Authors: Tsang, Ka Chun; 曾加駿

Year: 2022

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/311697

Thesis Tumor intrinsic pathways dictate the immune landscape and responses to immune checkpoint inhibitors in liver cancer

Yuen, Wai Hin; 袁瑋軒 · 2023 · University of Hong Kong · DOI

Full title: Tumor intrinsic pathways dictate the immune landscape and responses to immune checkpoint inhibitors in liver cancer

Authors: Yuen, Wai Hin; 袁瑋軒

Year: 2023

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/328606

Thesis Molecular mechanisms and therapeutic targets in genital tract malignant melanomas

Yu, Ying; 俞英 · 2019 · University of Hong Kong · DOI

Full title: Molecular mechanisms and therapeutic targets in genital tract malignant melanomas

Authors: Yu, Ying; 俞英

Year: 2019

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/266341

Thesis Hyperthermic Intrathoracic Chemotherapy Modulates the Immune Microenvironment of Pleural Mesothelioma and Improves the Impact of Dual Immune Checkpoint Inhibition

Hao, Yameng; Gkasti, Aspasia; Managh, Amy J. et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Hyperthermic Intrathoracic Chemotherapy Modulates the Immune Microenvironment of Pleural Mesothelioma and Improves the Impact of Dual Immune Checkpoint Inhibition

Authors: Hao, Yameng; Gkasti, Aspasia; Managh, Amy J.; Dagher, Julien; Sifis, Alexandros; Tiron, Luca; Chriqui, Louis-Emmanuel; Marie, Damien N.; Silva, Olga De Souza; Christodoulou, Michel; Peters, Solange; Joyce, Johanna A.; Krueger, Thorsten; Gonzalez, Michel; Abdelnour-Berchtold, Etienne; Sempoux, Christine; Clerc, Daniel; Teixeira-Farinha, Hugo; Hubner, Martin; Meylan, Etienne; Dyson, Paul J.; Cavin, Sabrina; Perentes, Jean Y.

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/252717

Thesis Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Authors: Ishihara, Jun; Ishihara, Ako; Sasaki, Koichi; Lee, Steve Seung-Young; Williford, John-Michael; Yasui, Mariko; Abe, Hiroyuki; Potin, Lambert; Hosseinchi, Peyman; Fukunaga, Kazuto; Raczy, Michal M.; Gray, Laura T.; Mansurov, Aslan; Katsumata, Kiyomitsu; Fukayama, Masashi; Kron, Stephen J.; Swartz, Melody A.; Hubbell, Jeffrey A.

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/157854

Thesis The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Martins, Filipe; Schiappacasse, Luis; Levivier, Marc et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Authors: Martins, Filipe; Schiappacasse, Luis; Levivier, Marc; Tuleasca, Constantin; Cuendet, Michel A.; Aedo-Lopez, Veronica; Gautron Moura, Bianca; Homicsko, Krisztian; Bettini, Adrienne; Berthod, Gregoire; Gerard, Camille L.; Wicky, Alexandre; Bourhis, Jean; Michielin, Olivier

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/166853

Thesis Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Martins, Filipe; Sofiya, Latifyan; Sykiotis, Gerasimos P. et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Authors: Martins, Filipe; Sofiya, Latifyan; Sykiotis, Gerasimos P.; Lamine, Faiza; Maillard, Michel; Fraga, Montserrat; Shabafrouz, Keyvan; Ribi, Camillo; Cairoli, Anne; Guex-Crosier, Yan; Kuntzer, Thierry; Michielin, Olivier; Peters, Solange; Coukos, Georges; Spertini, Francois; Thompson, John A.; Obeid, Michel

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/161124

Thesis COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION IN BREAST AND PANCREATIC CANCER

Keenan, Bridget P. · 2015 · Johns Hopkins University · DOI

Full title: COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION IN BREAST AND PANCREATIC CANCER

Authors: Keenan, Bridget P.

Year: 2015

Venue: Johns Hopkins University

DOI: http://jhir.library.jhu.edu/handle/1774.2/37977

Thesis Hyperthermic intrathoracic chemotherapy to control malignant pleural mesothelioma

Hao, Yameng · 2023 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Hyperthermic intrathoracic chemotherapy to control malignant pleural mesothelioma

Authors: Hao, Yameng

Year: 2023

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/197168

Thesis Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Authors: Ishihara, Jun; Fukunaga, Kazuto; Ishihara, Ako; Larsson, Hans M.; Potin, Lambert; Hosseinchi, Peyman; Galliverti, Gabriele; Swartz, Melody A.; Hubbell, Jeffrey A.

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/142581

Thesis Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Courlet, Perrine; Abler, Daniel; Guidi, Monia et al. · 2023 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Authors: Courlet, Perrine; Abler, Daniel; Guidi, Monia; Girard, Pascal; Amato, Federico; Violi, Naik Vietti; Dietz, Matthieu; Guignard, Nicolas; Wicky, Alexandre; Latifyan, Sofiya; De Micheli, Rita; Jreige, Mario; Dromain, Clarisse; Csajka, Chantal; Prior, John O.; Venkatakrishnan, Karthik; Michielin, Olivier; Cuendet, Michel A.; Terranova, Nadia

Year: 2023

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/199246

Thesis DECIPHERING TRANSCRIPTIONAL PROGRAMS OF CD8+ T CELLS ACROSS TREATMENT MODALITIES IN RESECTABLE LUNG CANCER

Connor, Sydney Christine · 2025 · Johns Hopkins University · DOI

Full title: DECIPHERING TRANSCRIPTIONAL PROGRAMS OF CD8+ T CELLS ACROSS TREATMENT MODALITIES IN RESECTABLE LUNG CANCER

Authors: Connor, Sydney Christine

Year: 2025

Venue: Johns Hopkins University

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70262

Thesis Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced antitumor T-cell responses

Beavis, PA; Milenkovski, N; Henderson, MA et al. · 2017 · University of Melbourne · DOI

Full title: Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced antitumor T-cell responses

Authors: Beavis, PA; Milenkovski, N; Henderson, MA; John, LB; Allard, B; Loi, S; Kershaw, MH; Stagg, J; Darcy, PK

Year: 2017

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/190464

Thesis Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015.

Nanda, VGY; Peng, W; Hwu, P et al. · 2020 · University of Melbourne · DOI

Full title: Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015.

Authors: Nanda, VGY; Peng, W; Hwu, P; Davies, MA; Ciliberto, G; Fattore, L; Malpicci, D; Aurisicchio, L; Ascierto, PA; Croce, CM; Mancini, R; Spranger, S; Gajewski, TF; Wang, Y; Ferrone, S; Vanpouille-Box, C; Wennerberg, E; Pilones, KA; Formenti, SC; Demaria, S; Tang, H; Wang, Y; Fu, Y-X; Dummer, R; Puzanov, I; Tarhini, A; Chauvin, J-M; Pagliano, O; Fourcade, J; Sun, Z; Wang, H; Sanders, C; Kirkwood, JM; Chen, T-HT; Maurer, M; Korman, AJ; Zarour, HM; Stroncek, DF; Huber, V; Rivoltini, L; Thurin, M; Rau, T; Lugli, A; Pagès, F; Camarero, J; Sancho, A; Jommi, C; de Coaña, YP; Wolodarski, M; Yoshimoto, Y; Gentilcore, G; Poschke, I; Masucci, GV; Hansson, J; Kiessling, R; Scognamiglio, G; Sabbatino, F; Marino, FZ; Anniciello, AM; Cantile, M; Cerrone, M; Scala, S; D’alterio, C; Ianaro, A; Cirin, G; Liguori, G; Bott, G; Chapman, PB; Robert, C; Larkin, J; Haanen, JB; Ribas, A; Hogg, D; Hamid, O; Testori, A; Lorigan, P; Sosman, JA; Flaherty, KT; Yue, H; Coleman, S; Caro, I; Hauschild, A; McArthur, GA; Sznol, M; Callahan, MK; Kluger, H; Postow, MA; Gordan, R; Segal, NH; Rizvi, NA; Lesokhin, A; Atkins, MB; Burke, MM; Ralabate, A; Rivera, A; Kronenberg, SA; Agunwamba, B; Ruisi, M; Horak, C; Jiang, J; Wolchok, J; Ascierto, PA; Liszkay, G; Maio, M; Mandalà, M; Demidov, L; Stoyakovskiy, D; Thomas, L; de la Cruz-Merino, L; Atkinson, V; Dutriaux, C; Garbe, C; Wongchenko, M; Chang, I; Koralek, DO; Rooney, I; Yan, Y; Dréno, B; Sullivan, R; Patel, M; Hodi, S; Amaria, R; Boasberg, P; Wallin, J; He, X; Cha, E; Richie, N; Ballinger, M; Smith, DC; Bauer, TM; Wasser, JS; Luke, JJ; Balmanoukian, AS; Kaufman, DR; Zhao, Y; Maleski, J; Leopold, L; Gangadhar, TC; Long, GV; Michielin, O; VanderWalde, A; Andtbacka, RHI; Cebon, J; Fernandez, E; Malvehy, J; Olszanski, AJ; Gause, C; Chen, L; Chou, J; Stephen Hodi, F; Brady, B; Mortier, L; Hassel, JC; Rutkowski, P; McNeil, C; Kalinka-Warzocha, E; Lebbé, C; Ny, L; Chacon, M; Queirolo, P; Loquai, C; Cheema, P; Berrocal, A; Eizmendi, KM; Bar-Sela, G; Horak, C; Hardy, H; Weber, JS; Grob, J-J; Marquez-Rodas, I; Schmidt, H; Briscoe, K; Baurain, J-F; Wolchok, JD; Pinto, R; De Summa, S; Garrisi, VM; Strippoli, S; Azzariti, A; Guida, G; Guida, M; Tommasi, S; Jacquelot, N; Enot, D; Flament, C; Pitt, JM; Vimond, N; Blattner, C; Yamazaki, T; Roberti, M-P; Vetizou, M; Daillere, R; Poirier-Colame, V; la Semeraro, M; Caignard, A; Slingluff, CL; Sallusto, F; Rusakiewicz, S; Weide, B; Marabelle, A; Kohrt, H; Dalle, S; Cavalcanti, A; Kroemer, G; Di Giacomo, AM; Maio, M; Wong, P; Yuan, J; Umansky, V; Eggermont, A; Zitvogel, L; Anna, P; Marco, T; Stefania, S; Francesco, M; Mariaelena, C; Gabriele, M; Antonio, AP; Franco, S; Roberti, MP; Enot, DP; Semeraro, M; Jégou, S; Flores, C; Chen, T-HT; Kwon, BS; Anderson, AC; Borg, C; Aubin, F; Ayyoub, M; De Presbiteris, AL; Cordaro, FG; Camerlingo, R; Fratangelo, F; Mozzillo, N; Pirozzi, G; Patriarca, EJ; Caputo, E; Motti, ML; Falcon, R; Miceli, R; Capone, M; Madonna, G; Mallardo, D; Carrier, MV; Panza, E; De Cicco, P; Armogida, C; Ercolano, G; Botti, G; Cirino, G; Sandru, A; Blank, M; Balatoni, T; Olasz, J; Farkas, E; Szollar, A; Savolt, A; Godeny, M; Csuka, O; Horvath, S; Eles, K; Shoenfeld, Y; Kasler, M; Costantini, S; Capone, F; Moradi, F; Berglund, P; Leandersson, K; Linnskog, R; Andersson, T; Prasad, CP; Nigro, CL; Lattanzio, L; Wang, H; Proby, C; Syed, N; Occelli, M; Cauchi, C; Merlano, M; Harwood, C; Thompson, A; Crook, T; Bifulco, K; Ingangi, V; Minopoli, M; Ragone, C; Pessi, A; Mannavola, F; D’Oronzo, S; Felici, C; Tucci, M; Doronzo, A; Silvestris, F; Ferretta, A; Guida, S; Maida, I; Cocco, T; Passarelli, A; Quaresmini, D; Franzese, O; Palermo, B; Di Donna, C; Sperduti, I; Foddai, M; Stabile, H; Gismondi, A; Santoni, A; Nisticò, P; Sponghini, AP; Platini, F; Marra, E; Rondonotti, D; Alabiso, O; Fierro, MT; Savoia, P; Stratica, F; Quaglino, P; Di Monta, G; Corrado, C; Di Marzo, M; Ugo, M; Di Cecilia, ML; Nicola, M; Fusciello, C; Marra, A; Guarrasi, R; Baldi, C; Russo, R; Di Giulio, G; Faiola, V; Zeppa, P; Pepe, S; Gambale, E; Carella, C; Di Paolo, A; De Tursi, M; Marra, L; De Murtas, F; Sorrentino, V; Voinea, S; Panaitescu, E; Bolovan, M; Stanciu, A; Cinca, S; Botti, C; Aquino, G; Anniciello, A; Fortes, C; Mastroeni, S; Caggiati, A; Passarelli, F; Zappalà, A; Capuano, M; Bono, R; Nudo, M; Marino, C; Michelozzi, P; De Biasio, V; Battarra, VC; Formenti, S; Ascierto, ML; McMiller, TL; Berger, AE; Danilova, L; Anders, RA; Netto, GJ; Xu, H; Pritchard, TS; Fan, J; Cheadle, C; Cope, L; Drake, CG; Pardoll, DM; Taube, JM; Topalian, SL; Gnjatic, S; Nataraj, S; Imai, N; Rahman, A; Jungbluth, AA; Pan, L; Venhaus, R; Park, A; Lehmann, FF; Lendvai, N; Cohen, AD; Cho, HJ; Daniel, S; Hirsh, V

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/256123

Thesis Immune checkpoint inhibitors for advanced non-small cell lung cancer: Emerging sequencing for new treatment targets

Aguiar, PN; De Mello, RA; Barreto, CMN et al. · 2021 · University of Melbourne · DOI

Full title: Immune checkpoint inhibitors for advanced non-small cell lung cancer: Emerging sequencing for new treatment targets

Authors: Aguiar, PN; De Mello, RA; Barreto, CMN; Perry, LA; Penny-Dimri, J; Tadokoro, H; De Lima Lopes, G

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/287820

Thesis Immunotherapy of Esophageal Cancer: Current Status, Many Trials and

Alsina, Maria; Moehler, Markus; Lorenzen, Sylvie · 2018 · Technical University of Munich (TUM) · DOI

Full title: Immunotherapy of Esophageal Cancer: Current Status, Many Trials and

Authors: Alsina, Maria;Moehler, Markus;Lorenzen, Sylvie

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1586997

Thesis [Advanced bladder cancer : From chemo- to immunotherapy].

Horn, T; Krege, S; Retz, M · 2018 · Technical University of Munich (TUM) · DOI

Full title: [Advanced bladder cancer : From chemo- to immunotherapy].

Authors: Horn, T;Krege, S;Retz, M

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1586464

Thesis Current systemic treatment of metastatic bladder cancer

Horn, T.; von Amsberg, G.; Tauber, R. et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: Current systemic treatment of metastatic bladder cancer

Authors: Horn, T.;von Amsberg, G.;Tauber, R.;Retz, M.

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587016

Thesis 50 years of systemic therapy of urinary bladder cancer

Retz, Margitta; von Amsberg, Gunhild; Horn, Thomas et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: 50 years of systemic therapy of urinary bladder cancer

Authors: Retz, Margitta;von Amsberg, Gunhild;Horn, Thomas;Gschwend, Juergen E.;Maisch, Philipp

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588421

Thesis Morphomolecular analysis of the immune tumor microenvironment in human head and neck cancer.

Badr, Mohamed; Jöhrens, Korinna; Allgäuer, Michael et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Morphomolecular analysis of the immune tumor microenvironment in human head and neck cancer.

Authors: Badr, Mohamed;Jöhrens, Korinna;Allgäuer, Michael;Boxberg, Melanie;Weichert, Wilko;Tinhofer, Ingeborg;Denkert, Carsten;Schirmacher, Peter;Stenzinger, Albrecht;Budczies, Jan

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1587935

Thesis Translational Highlights in Breast and Ovarian Cancer 2019 - Immunotherapy, DNA Repair, PI3K Inhibition and CDK4/6 Therapy.

Hartkopf, Andreas D; Müller, Volkmar; Wöckel, Achim et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Translational Highlights in Breast and Ovarian Cancer 2019 - Immunotherapy, DNA Repair, PI3K Inhibition and CDK4/6 Therapy.

Authors: Hartkopf, Andreas D;Müller, Volkmar;Wöckel, Achim;Lux, Michael P;Janni, Wolfgang;Ettl, Johannes;Belleville, Erik;Schütz, Florian;Fasching, Peter A;Kolberg, Hans-Christian;Welslau, Manfred;Overkamp, Friedrich;Taran, Florin-Andrei;Brucker, Sara Y;Wallwiener, Markus;Tesch, Hans;Fehm, Tanja N;Schneeweiss, Andreas;Lüftner, Diana

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588982

Thesis Current status of immunotherapy in gastrointestinal malignancies.

Lorenzen, Sylvie; Lordick, Florian; Loosen, Sven Heiko et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Current status of immunotherapy in gastrointestinal malignancies.

Authors: Lorenzen, Sylvie;Lordick, Florian;Loosen, Sven Heiko;Tacke, Frank;Trautwein, Christian;Roderburg, Christoph;Ettrich, Thomas J;Perkhofer, Lukas;Reinacher-Schick, Anke;Stein, Alexander

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588789

Thesis Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217).

Tintelnot, Joseph; Goekkurt, Eray; Binder, Mascha et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217).

Authors: Tintelnot, Joseph;Goekkurt, Eray;Binder, Mascha;Thuss-Patience, Peter;Lorenzen, Sylvie;Knorrenschild, Jorge Riera;Kretzschmar, Albrecht;Ettrich, Thomas;Lindig, Udo;Jacobasch, Lutz;Pink, Daniel;Al-Batran, Salah-Eddin;Hinke, Axel;Hegewisch-Becker, Susanna;Nilsson, Sven;Bokemeyer, Carsten;Stein, Alexander

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588790

Thesis The Systemic Treatment of Melanoma.

Terheyden, Patrick; Krackhardt, Angela; Eigentler, Thomas · 2019 · Technical University of Munich (TUM) · DOI

Full title: The Systemic Treatment of Melanoma.

Authors: Terheyden, Patrick;Krackhardt, Angela;Eigentler, Thomas

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1589630

Thesis RIG-I activation is critical for responsiveness to checkpoint blockade.

Heidegger, Simon; Wintges, Alexander; Stritzke, Florian et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: RIG-I activation is critical for responsiveness to checkpoint blockade.

Authors: Heidegger, Simon;Wintges, Alexander;Stritzke, Florian;Bek, Sarah;Steiger, Katja;Koenig, Paul-Albert;Göttert, Sascha;Engleitner, Thomas;Öllinger, Rupert;Nedelko, Tatiana;Fischer, Julius C;Makarov, Vladimir;Winter, Christof;Rad, Roland;van den Brink, Marcel R M;Ruland, Jürgen;Bassermann, Florian;Chan, Timothy A;Haas, Tobias;Poeck, Hendrik

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1589747

Thesis Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Liu, David; Schilling, Bastian; Liu, Derek et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Authors: Liu, David;Schilling, Bastian;Liu, Derek;Sucker, Antje;Livingstone, Elisabeth;Jerby-Amon, Livnat;Zimmer, Lisa;Gutzmer, Ralf;Satzger, Imke;Loquai, Carmen;Grabbe, Stephan;Vokes, Natalie;Margolis, Claire A;Conway, Jake;He, Meng Xiao;Elmarakeby, Haitham;Dietlein, Felix;Miao, Diana;Tracy, Adam;Gogas, Helen;Goldinger, Simone M;Utikal, Jochen;Blank, Christian U;Rauschenberg, Ricarda;von Bubnoff, Dagmar;Krackhardt, Angela;Weide, Benjamin;Haferkamp, Sebastian;Kiecker, Felix;Izar, Ben;Garraway, Levi;Regev, Aviv;Flaherty, Keith;Paschen, Annette;Van Allen, Eliezer M;Schadendorf, Dirk

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590103

Thesis Novel Approaches to Improve the Efficacy of Immuno-Radiotherapy.

Shevtsov, Maxim; Sato, Hiro; Multhoff, Gabriele et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Novel Approaches to Improve the Efficacy of Immuno-Radiotherapy.

Authors: Shevtsov, Maxim;Sato, Hiro;Multhoff, Gabriele;Shibata, Atsushi

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1590311

Thesis Neoadjuvant anti-programmed Death-1 immunotherapy by Pembrolizumab in resectable nodal positive stage II/IIIa non-small-cell lung cancer (NSCLC): the NEOMUN trial.

Eichhorn, Florian; Klotz, Laura V; Bischoff, Helge et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: Neoadjuvant anti-programmed Death-1 immunotherapy by Pembrolizumab in resectable nodal positive stage II/IIIa non-small-cell lung cancer (NSCLC): the NEOMUN trial.

Authors: Eichhorn, Florian;Klotz, Laura V;Bischoff, Helge;Thomas, Michael;Lasitschka, Felix;Winter, Hauke;Hoffmann, Hans;Eichhorn, Martin E

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588557

Thesis Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

Kabacaoglu, Derya; Ciecielski, Katrin J; Ruess, Dietrich A et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.

Authors: Kabacaoglu, Derya;Ciecielski, Katrin J;Ruess, Dietrich A;Algül, Hana

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1591855

Thesis [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].

Miller, Kurt; Bergmann, Lothar; Doehn, Christian et al. · 2019 · Technical University of Munich (TUM) · DOI

Full title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].

Authors: Miller, Kurt;Bergmann, Lothar;Doehn, Christian;Gschwend, Jürgen E;Kuczyk, Markus A

Year: 2019

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1591191

Thesis ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer.

Sonpavde, Guru; Necchi, Andrea; Gupta, Shilpa et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer.

Authors: Sonpavde, Guru;Necchi, Andrea;Gupta, Shilpa;Steinberg, Gary D;Gschwend, Juergen E;Van Der Heijden, Michiel Simon;Garzon, Nathalie;Ibrahim, Mohammed;Raybold, Bradley;Liaw, Danny;Rutstein, Mark;Galsky, Matt D

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1617192

Thesis Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer - study protocol of a prospective, single arm, multicenter phase II trial (RACE IT).

Schmid, Sebastian C; Koll, Florestan J; Rödel, Claus et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer - study protocol of a prospective, single arm, multicenter phase II trial (RACE IT).

Authors: Schmid, Sebastian C;Koll, Florestan J;Rödel, Claus;Maisch, Philipp;Sauter, Andreas;Beckert, Franziska;Seitz, Anna;Kübler, Hubert;Flentje, Michael;Chun, Felix;Combs, Stephanie E;Schiller, Kilian;Gschwend, Jürgen E;Retz, Margitta

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1597239

Thesis Pembrolizumab Combination Therapies in Patients With Metastatic Castration-Resistant Prostate Cancer: Cohorts A-C of the Phase 1b/2 KEYNOTE-365 Study

Joshua, Anthony M.; Gurney, Howard; Retz, Margitta et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Pembrolizumab Combination Therapies in Patients With Metastatic Castration-Resistant Prostate Cancer: Cohorts A-C of the Phase 1b/2 KEYNOTE-365 Study

Authors: Joshua, Anthony M.;Gurney, Howard;Retz, Margitta;Tafreshi, Ali;Fong, Peter;Shore, Neal;Romano, Emanuela;Augustin, Marinela;Piulats, Josep M.;Berry, William R.;Kolinsky, Michael Paul;Sridhar, Srikala S.;Conter, Henry Joacob;Todenhofer, Tilman;Appleman, Leonard J.;Wu, Haiyan;Schloss, Charles;Poehlein, Christian Heinrich;de Bono, Johann S.;Yu, Evan Y.

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1617270

Thesis Mechanisms of T-Cell Exhaustion in Pancreatic Cancer.

Saka, Didem; Gökalp, Muazzez; Piyade, Betül et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Mechanisms of T-Cell Exhaustion in Pancreatic Cancer.

Authors: Saka, Didem;Gökalp, Muazzez;Piyade, Betül;Cevik, Nedim Can;Arik Sever, Elif;Unutmaz, Derya;Ceyhan, Güralp O;Demir, Ihsan Ekin;Asimgil, Hande

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1617420

Thesis Tumor Interferon Signaling Initiates And Sustains A Multigenic Resistance Program To Immune Checkpoint Blockade

Benci, Joseph Lawrence · 2023 · University of Pennsylvania · DOI

Full title: Tumor Interferon Signaling Initiates And Sustains A Multigenic Resistance Program To Immune Checkpoint Blockade

Authors: Benci, Joseph Lawrence

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/29076

Thesis Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients.

Amaral, Teresa; Kiecker, Felix; Schaefer, Sarah et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients.

Authors: Amaral, Teresa;Kiecker, Felix;Schaefer, Sarah;Stege, Henner;Kaehler, Katharina;Terheyden, Patrick;Gesierich, Anja;Gutzmer, Ralf;Haferkamp, Sebastian;Uttikal, Jochen;Berking, Carola;Rafei-Shamsabadi, David;Reinhardt, Lydia;Meier, Friedegund;Karoglan, Ante;Posch, Christian;Gambichler, Thilo;Pfoehler, Claudia;Thoms, Kai;Tietze, Julia;Debus, Dirk;Herbst, Rudolf;Emmert, Steffen;Loquai, Carmen;Hassel, Jessica C;Meiss, Frank;Tueting, Thomas;Heinrich, Vanessa;Eigentler, Thomas;Garbe, Claus;Zimmer, Lisa

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1618364

Thesis Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma.

Hoffmann, Friederike; Zarbl, Romina; Niebel, Dennis et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma.

Authors: Hoffmann, Friederike;Zarbl, Romina;Niebel, Dennis;Sirokay, Judith;Fröhlich, Anne;Posch, Christian;Holderried, Tobias A W;Brossart, Peter;Saavedra, Gonzalo;Kuster, Pia;Strieth, Sebastian;Gielen, Gerrit H;Ring, Sandra S;Dietrich, Jörn;Pietsch, Torsten;Flatz, Lukas;Kristiansen, Glen;Landsberg, Jennifer;Dietrich, Dimo

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1618350

Thesis Induction of T Cell Immunity Overcomes Resistance to Pd-1 and Ctla-4 Blockade and Improves Survival in Pancreatic Cancer

Winograd, Rafael · 2023 · University of Pennsylvania · DOI

Full title: Induction of T Cell Immunity Overcomes Resistance to Pd-1 and Ctla-4 Blockade and Improves Survival in Pancreatic Cancer

Authors: Winograd, Rafael

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/27947

Thesis Determinants Of Adaptive Immunity In Cancer

Rech, Andrew J · 2023 · University of Pennsylvania · DOI

Full title: Determinants Of Adaptive Immunity In Cancer

Authors: Rech, Andrew J

Year: 2023

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/29472

Thesis Peripheral T cell responses to immunotherapy treatment in metastatic melanoma

Woodcock, V · 2019 · University of Oxford - ORA · DOI

Full title: Peripheral T cell responses to immunotherapy treatment in metastatic melanoma

Authors: Woodcock, V

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:02358ddb-9684-477c-9725-32eb469beb6d

Thesis RAS INHIBITION AND ANTI-TUMOR IMMUNITY IN PANCREATIC CANCER

Orlen, Margo, Isabelle · 2025 · University of Pennsylvania · DOI

Full title: RAS INHIBITION AND ANTI-TUMOR IMMUNITY IN PANCREATIC CANCER

Authors: Orlen, Margo, Isabelle

Year: 2025

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/61644

Thesis T cells in HBV associated hepatocellular carcinoma and other cancers

Li, X · 2017 · University of Oxford - ORA · DOI

Full title: T cells in HBV associated hepatocellular carcinoma and other cancers

Authors: Li, X

Year: 2017

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:bb17db80-554e-453c-8daa-c550fea30cc2

Thesis Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer

Watson, RA · 2023 · University of Oxford - ORA · DOI

Full title: Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer

Authors: Watson, RA

Year: 2023

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:88185ee9-89db-4f20-a54b-ae112260c386

Thesis Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers et al. · 2015 · Technical University of Denmark (DTU) · DOI

Full title: Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Authors: Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers; id_orcid 0000-0003-3147-6960

Year: 2015

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/66a425e1-b542-4f31-9f8e-8ef59b388018

Thesis Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Authors: Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff; Nielsen, Morten; Borch, Troels Holz; Olsen, Lars Rønn; id_orcid 0000-0002-6725-7850; Aasbjerg, Gitte; Santegoets, Saskia J.; van der Burg, Sjoerd H.; Milne, Katy; Nelson, Brad H.; Met, Özcan; Donia, Marco; Svane, Inge Marie

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191

Thesis Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients

Fang, Chao; Fang, Wenfeng; Xu, Liqin et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients

Authors: Fang, Chao; Fang, Wenfeng; Xu, Liqin; Gao, Fangfang; Hou, Yong; Zou, Hua; Ma, Yuxiang; Moll, Janne Marie; id_orcid 0000-0002-3514-4528; Yang, Yunpeng; Wang, Dan; Huang, Yan; Ren, Huahui; Zhao, Hongyun; Qin, Shishang; Zhong, Huanzi; Li, Junhua; Liu, Sheng; Yang, Huanming; Wang, Jian; Brix, Susanne; id_orcid 0000-0001-8951-6705; Kristiansen, Karsten; Zhang, Li

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/3a8936c9-b3f7-4342-b013-3d5b709cdbe0

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke et al. · 2017 · Technical University of Denmark (DTU) · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke; Rosenkrantz, Lisbet Holmich; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/25caf41f-8965-4658-b672-f62d5d7ff1d3

Thesis Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

Gaißler, Andrea; Meldgaard, Trine Sundebo; Heeke, Christina et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

Authors: Gaißler, Andrea; Meldgaard, Trine Sundebo; Heeke, Christina; Babaei, Sepideh; Tvingsholm, Siri Amanda; Bochem, Jonas; Spreuer, Janine; Amaral, Teresa; Wagner, Nikolaus Benjamin; Klein, Reinhild; Meier, Friedegund; Garbe, Claus; Eigentler, Thomas K.; Pawelec, Graham; Claassen, Manfred; Weide, Benjamin; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Wistuba-Hamprecht, Kilian

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/3b41484f-055a-42d1-b260-1a5584f8938a

Thesis Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Authors: Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise; Khan, Shawez; Fjæstad, Klaire Yixin; Brøchner, Christian Beltoft; Linder, Hannes; Ankjærgaard, Christina; id_orcid 0000-0001-5620-6663; Donia, Marco; Chen, Inna; Nielsen, Dorte Lisbet; Behrens, Claus Preibisch; id_orcid 0000-0002-0686-1421; Madsen, Daniel Hargbøl

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/7ba8c0c4-d95a-4084-9cc1-ebe6ba9f1cb6

Thesis Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Authors: Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius; Østrup, Olga; Yde, Christina Westmose; Eklund, Aron Charles; Mau-Sørensen, Morten; Barra, Carolina; id_orcid 0000-0002-6836-4906; Svane, Inge Marie; Nielsen, Finn Cilius; Funt, Samuel A.; Lassen, Ulrik; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/6f236ce4-64f3-4b8e-931d-050ca22e0acc

Thesis Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

Authors: Araujo B. de Lima, Vinicius; Hansen, Morten; Spanggaard, Iben; Rohrberg, Kristoffer; Reker Hadrup, Sine; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a2066594-9c4f-4789-98cd-954e4dedb11a

Thesis Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Hulen, Thomas Morgan; Friese, Christina; Kristensen, Nikolaj Pagh et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/dd214e21-2ea3-4190-9abd-0fde4c243316

Thesis Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

McGranahan, Nicholas; Furness, Andrew J S; Rosenthal, Rachel et al. · 2016 · Technical University of Denmark (DTU) · DOI

Full title: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Year: 2016

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/c36e3271-a3d9-46b6-b0d1-d3537ae20249

Thesis Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Skadborg, Signe K.; Maarup, Simone; Draghi, Arianna et al. · 2024 · Technical University of Denmark (DTU) · DOI

Full title: Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/f4f16359-bd83-400f-9fb9-cc2e8d28b17f

Thesis Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Litchfield, Kevin; Reading, James L.; Puttick, Clare et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Authors: Litchfield, Kevin; Reading, James L.; Puttick, Clare; Thakkar, Krupa; Abbosh, Chris; Bentham, Robert; Watkins, Thomas B.K.; Rosenthal, Rachel; Biswas, Dhruva; Rowan, Andrew; Lim, Emilia; Al Bakir, Maise; Turati, Virginia; Guerra-Assunção, José Afonso; Conde, Lucia; Furness, Andrew J.S.; Saini, Sunil Kumar; id_orcid 0000-0003-3382-9432; Hadrup, Sine R.; id_orcid 0000-0002-5937-4344; Herrero, Javier; Lee, Se Hoon; Van Loo, Peter; Enver, Tariq; Larkin, James; Hellmann, Matthew D.; Turajlic, Samra; Quezada, Sergio A.; McGranahan, Nicholas; Swanton, Charles

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/be9a3441-87ad-4fde-96b8-5d79eb7f3c5e

Thesis Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

Gaißler, Andrea; Meldgaard, Trine Sundebo; Heeke, Christina et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/3b41484f-055a-42d1-b260-1a5584f8938a

Thesis Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Authors: Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus; Hasselager, Thomas; Olsen, Lars Rønn; id_orcid 0000-0002-6725-7850; Anglesio, Michael S.; Borch, Troels Holz; Kennedy, Mia; Briggs, Gillian; Ledoux, Stacey; Kreuzinger, Caroline; von der Decken, Isabel; Donia, Marco; Castillo-Tong, Dan Cacsire; Nelson, Brad H.; Svane, Inge Marie

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/904a44aa-c867-4721-a512-23240a1e06e3

Thesis Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Kverneland, Anders Handrup; Pedersen, Magnus; Westergaard, Marie Christine Wulff et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191

Thesis Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Tardos, Elisa Catafal · 2024 · Technical University of Denmark (DTU) · DOI

Full title: Targeting Human γδ T Cells by Checkpoint Inhibitors in Cancer

Authors: Tardos, Elisa Catafal

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/c1afaaf9-c0a2-4ecd-9361-2f3b8d8c2788

Thesis Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma

Kelderman, Sander; Heemskerk, Bianca; van Tinteren, Harm et al. · 2014 · Technical University of Denmark (DTU) · DOI

Full title: Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma

Authors: Kelderman, Sander; Heemskerk, Bianca; van Tinteren, Harm; van den Brom, Rob R. H.; A. P. Hospers, Geke; van den Eertwegh, Alfonsus J. M.; W. Kapiteijn, Ellen; Willem B. de Groot, Jan; Soetekouw, Patricia; L. Jansen, Rob; Fiets , Edward; J. S. Furness, Andrew; Renn, Alexandra; Krzystanek, Marcin; Szallasi, Zoltan Imre; Lorigan, Paul; Gore, Martin E.; N. M. Schumacher, Ton; B. A. G. Haanen, John; Larkin, James M.G.; U. Blank, Christian

Year: 2014

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/0d36d3a1-3e0e-4c74-addd-9a79be4ec4f6

Thesis Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

de Lima, Vinicius Araujo B.; Borch, Annie; Hansen, Morten et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

Authors: de Lima, Vinicius Araujo B.; Borch, Annie; Hansen, Morten; Draghi, Arianna; Spanggaard, Iben; Rohrberg, Kristoffer; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Lassen, Ulrik; Svane, Inge Marie

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/09aacc10-7dff-4078-947b-c2af24b266f4

Thesis Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

Kverneland, Anders Handrup; Enevold, Christian; Donia, Marco et al. · 2018 · University of Copenhagen · DOI

Full title: Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

Authors: Kverneland, Anders Handrup; Enevold, Christian; Donia, Marco; Bastholt, Lars; Svane, Inge Marie; Nielsen, Claus H

Year: 2018

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/46259398-9f9b-448c-bc62-9a861a4cd7e9

Thesis Nivolumab with or without Ipilimumab Combined with Stereotactic Body Radiotherapy in Patients with Metastatic Biliary Tract Cancer:A Randomized Phase 2 Study

Markussen, Alice; Johansen, Julia S.; Larsen, Finn O. et al. · 2024 · Technical University of Denmark (DTU) · DOI

Full title: Nivolumab with or without Ipilimumab Combined with Stereotactic Body Radiotherapy in Patients with Metastatic Biliary Tract Cancer:A Randomized Phase 2 Study

Authors: Markussen, Alice; Johansen, Julia S.; Larsen, Finn O.; Theile, Susann; Hasselby, Jane P.; Willemoe, Gro L.; Lorentzen, Torben; Madsen, Kasper; Høgdall, Estrid; Poulsen, Tim S.; Wilken, Eva E.; Geertsen, Poul; Behrens, Claus P.; id_orcid 0000-0002-0686-1421; Svane, Inge M.; Nielsen, Dorte; Chen, Inna M.

Year: 2024

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/3cf3ae48-2b4c-4503-b2c3-fb9d710f25c4

Thesis Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Johansen, Astrid Zedlitz; Carretta, Marco; Thorseth, Marie-Louise et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/7ba8c0c4-d95a-4084-9cc1-ebe6ba9f1cb6

Thesis Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients

Fang, Chao; Fang, Wenfeng; Xu, Liqin et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/3a8936c9-b3f7-4342-b013-3d5b709cdbe0

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke et al. · 2017 · Technical University of Denmark (DTU) · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjørn, Jon; Lyngaa, Rikke Birgitte; Andersen, Rikke; Rosenkrantz, Lisbet Holmich; Hadrup, Sine Reker; id_orcid 0000-0002-5937-4344; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/25caf41f-8965-4658-b672-f62d5d7ff1d3

Thesis Predictors of responses to immune checkpoint blockade in advanced melanoma

Jacquelot, N; Roberti, M P; Enot, D P et al. · 2017 · University of Copenhagen · DOI

Full title: Predictors of responses to immune checkpoint blockade in advanced melanoma

Authors: Jacquelot, N; Roberti, M P; Enot, D P; Rusakiewicz, S; Ternès, N; Jegou, S; Woods, D M; Sodré, A L; Hansen, M; Meirow, Y; Sade-Feldman, M; Burra, A; Kwek, S S; Flament, C; Messaoudene, M; Duong, C P M; Chen, L; Kwon, B S; Anderson, A C; Kuchroo, V K; Weide, B; Aubin, F; Borg, C; Dalle, S; Beatrix, O; Ayyoub, M; Balme, B; Tomasic, G; Di Giacomo, A M; Maio, M; Schadendorf, D; Melero, I; Dréno, B; Khammari, A; Dummer, R; Levesque, M; Koguchi, Y; Fong, L; Lotem, M; Baniyash, M; Schmidt, H; Svane, I M; Kroemer, G; Marabelle, A; Michiels, S; Cavalcanti, A; Smyth, M J; Weber, J S; Eggermont, A M; Zitvogel, L

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/5e126806-9328-4dd2-8faf-9ef61a088635

Thesis Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Borch, Annie; Bjerregaard, Anne Mette; Araujo Barbosa de Lima, Vinicius et al. · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/6f236ce4-64f3-4b8e-931d-050ca22e0acc

Thesis Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers et al. · 2015 · Technical University of Denmark (DTU) · DOI

Full title: Checkpoint inhibitors in cancer immunotherapy: Cross reactivity of a CTLA-4 antibody and IDO-inhibitor L-1MT in pigs

Authors: Al-Shatrawi, Zina Adil; Frøsig, Thomas Mørch; Jungersen, Gregers; id_orcid 0000-0003-3147-6960

Year: 2015

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/66a425e1-b542-4f31-9f8e-8ef59b388018

Thesis Effects of immune checkpoint inhibitor-based combination therapies on the gut microbiota in advanced melanoma patients

Li, J.; Xu, L.; Peng, Z. et al. · 2022 · Technical University of Denmark (DTU) · DOI

Full title: Effects of immune checkpoint inhibitor-based combination therapies on the gut microbiota in advanced melanoma patients

Authors: Li, J.; Xu, L.; Peng, Z.; Jiang, H.; Chao, F.; Ding, Y.; Moll, J. M.; id_orcid 0000-0002-3514-4528; Li, D.; Wen, X.; Wang, J.; Ding, Q.; Zhang, L.; Kristiansen, K.; Brix, S.; id_orcid 0000-0001-8951-6705; Zhang, X.

Year: 2022

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/95cda558-5c4d-41f3-8d04-ed388517083b

Thesis Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Westergaard, Marie Christine Wulff; Milne, Katy; Pedersen, Magnus et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/904a44aa-c867-4721-a512-23240a1e06e3

Thesis Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjoern, Jon; Lyngaa, Rikke; Andersen, Rikke et al. · 2017 · University of Copenhagen · DOI

Full title: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Authors: Bjoern, Jon; Lyngaa, Rikke; Andersen, Rikke; Rosenkrantz, Lisbet Hölmich; Hadrup, Sine Reker; Donia, Marco; Svane, Inge Marie

Year: 2017

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/a922dd04-bba2-4ccc-adac-af06273d2557

Thesis Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

Jensen, Christina; Madsen, Daniel Hargbøl; Hansen, Morten et al. · 2018 · University of Copenhagen · DOI

Full title: Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

Authors: Jensen, Christina; Madsen, Daniel Hargbøl; Hansen, Morten; Schmidt, Henrik; Svane, Inge Marie; Karsdal, Morten Asser; Willumsen, Nicholas

Year: 2018

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/bc5c7559-c561-4036-b9f5-f6807d3400c1

Thesis Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Litchfield, Kevin; Reading, James L.; Puttick, Clare et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/be9a3441-87ad-4fde-96b8-5d79eb7f3c5e

Thesis IN RESPONSE: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A cohort study

van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Dekkers, Olaf M et al. · 2021 · Utrecht University · DOI

Full title: IN RESPONSE: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A cohort study

Authors: van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Dekkers, Olaf M; Kapiteijn, Ellen

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/443705

Thesis The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

The International Immuno-Oncology Biomarker Working Group · 2021 · Utrecht University · DOI

Full title: The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Authors: The International Immuno-Oncology Biomarker Working Group

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445470

Thesis High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial

van Dorp, Jeroen; Pipinikas, Christodoulos; Suelmann, Britt B.M. et al. · 2023 · Utrecht University · DOI

Full title: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial

Authors: van Dorp, Jeroen; Pipinikas, Christodoulos; Suelmann, Britt B.M.; Mehra, Niven; van Dijk, Nick; Marsico, Giovanni; van Montfoort, Maurits L.; Hackinger, Sophie; Braaf, Linde M.; Amarante, Tauanne; van Steenis, Charlaine; McLay, Kirsten; Daletzakis, Antonios; van den Broek, Daan; van de Kamp, Maaike W.; Hendricksen, Kees; de Feijter, Jeantine M.; Boellaard, Thierry N.; Meijer, Richard P.; van der Heijden, Toine G.; Rosenfeld, Nitzan; van Rhijn, Bas W.G.; Jones, Greg; van der Heijden, Michiel S.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/448678

Thesis Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

UNICIT consortium · 2023 · Utrecht University · DOI

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Authors: UNICIT consortium

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/450123

Thesis Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M et al. · 2024 · Utrecht University · DOI

Full title: Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Authors: Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M; Keller, Kaylee M; Barisa, Marta; Poon, Evon; Munnings-Tomes, Sophie; Himsworth, Courtney; Calton, Elizabeth; Rodriguez, Ana; Bernardi, Ronald; van den Ham, Femke; van Hooff, Sander R; Matser, Yvette A H; Tas, Michelle L; Langenberg, Karin P S; Lijnzaad, Philip; Borst, Anne L; Zappa, Elisa; Bergsma, Francisca J; Strijker, Josephine G M; Verhoeven, Bronte M; Mei, Shenglin; Kramdi, Amira; Restuadi, Restuadi; Sanchez-Bernabeu, Alvaro; Cornel, Annelisa M; Holstege, Frank C P; Gray, Juliet C; Tytgat, Godelieve A M; Scheijde-Vermeulen, Marijn A; Wijnen, Marc H W A; Dierselhuis, Miranda P; Straathof, Karin; Behjati, Sam; Wu, Wei; Heck, Albert J R; Koster, Jan; Nierkens, Stefan; Janoueix-Lerosey, Isabelle; de Krijger, Ronald R; Baryawno, Ninib; Chesler, Louis; Anderson, John; Caron, Hubert N; Margaritis, Thanasis; van Noesel, Max M; Molenaar, Jan J

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/451805

Thesis Nivolumab with or without ipilimumab in patients with recurrent or metastatic cervical cancer (CheckMate 358): a phase 1-2, open-label, multicohort trial

Oaknin, Ana; Moore, Kathleen; Meyer, Tim et al. · 2024 · Utrecht University · DOI

Full title: Nivolumab with or without ipilimumab in patients with recurrent or metastatic cervical cancer (CheckMate 358): a phase 1-2, open-label, multicohort trial

Authors: Oaknin, Ana; Moore, Kathleen; Meyer, Tim; López-Picazo González, José; Devriese, Lot A; Amin, Asim; Lao, Christopher D; Boni, Valentina; Sharfman, William H; Park, Jong Chul; Tahara, Makoto; Topalian, Suzanne L; Magallanes, Manuel; Molina Alavez, Alejandro; Khan, Tariq Aziz; Copigneaux, Catherine; Lee, Michelle; Garnett-Benson, Charlie; Wang, Xuya; Naumann, R Wendel

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/452541

Thesis Neo-adjuvant immunotherapy emerges as best medical practice, and will be the new standard of care for macroscopic stage III melanoma

van Akkooi, Alexander C.J.; Blank, Christian; Eggermont, Alexander M.M. · 2023 · Utrecht University · DOI

Full title: Neo-adjuvant immunotherapy emerges as best medical practice, and will be the new standard of care for macroscopic stage III melanoma

Authors: van Akkooi, Alexander C.J.; Blank, Christian; Eggermont, Alexander M.M.

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/458632

Thesis European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment – Update 2024

On behalf of the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC) · 2025 · Utrecht University · DOI

Full title: European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment – Update 2024

Authors: On behalf of the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC)

Year: 2025

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/459958

Thesis Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A et al. · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/132258

Thesis Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Regev, Aviv · 2022 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Authors: Regev, Aviv

Year: 2022

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/136118.2

Thesis Immunotoxin Monotherapy and Combinatorial Therapy With Immune Checkpoint Inhibitors for Malignant Brain Tumors

Bao, Xuhui · 2017 · Duke University · DOI

Full title: Immunotoxin Monotherapy and Combinatorial Therapy With Immune Checkpoint Inhibitors for Malignant Brain Tumors

Authors: Bao, Xuhui

Year: 2017

Venue: Duke University

DOI: https://hdl.handle.net/10161/13365

Thesis Immunoglobulin G and Subclasses as Potential Biomarkers in Metastatic Melanoma Patients Starting Checkpoint Inhibitor Treatment

Diem, S; Fässler, M; Bomze, D et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Immunoglobulin G and Subclasses as Potential Biomarkers in Metastatic Melanoma Patients Starting Checkpoint Inhibitor Treatment

Authors: Diem, S; Fässler, M; Bomze, D; Ali, OH; Berner, F; Niederer, R; Hillmann, D; Mangana, J; Levesque, MP; Dummer, R; Risch, L; Recher, M; Risch, M; Flatz, L

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/40297

Thesis Integrated analysis of immunotherapy treated clear cell renal cell carcinomas: An exploratory study

Sobottka, Bettina; Nienhold, Ronny; Nowak, Marta et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Integrated analysis of immunotherapy treated clear cell renal cell carcinomas: An exploratory study

Authors: Sobottka, Bettina; Nienhold, Ronny; Nowak, Marta; Hench, Juergen; Haeuptle, Pirmin; Frank, Angela; Sachs, Melanie; Kahraman, Abdullah; Moch, Holger; Koelzer, Viktor H.; Mertz, Kirsten D.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/126697

Thesis Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Klepsch, V; Hermann-Kleiter, N; Do-Dinh, P et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Authors: Klepsch, V; Hermann-Kleiter, N; Do-Dinh, P; Jakic, B; Offermann, A; Efremova, M; Sopper, S; Rieder, D; Krogsdam, A; Gamerith, G; Perner, S; Tzankov, A; Trajanoski, Z; Wolf, D; Baier, G

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/39136

Thesis The PD-1/PD-L1 pathway: Biological background and clinical relevance of an emerging treatment target in immunotherapy

Muenst, S; Soysal, SD; Tzankov, A et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: The PD-1/PD-L1 pathway: Biological background and clinical relevance of an emerging treatment target in immunotherapy

Authors: Muenst, S; Soysal, SD; Tzankov, A; Hoeller, S

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/27511

Thesis Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma

Schlosser, H. A.; Drebber, U.; Kloth, M. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma

Authors: Schlosser, H. A.; Drebber, U.; Kloth, M.; Thelen, M.; Rothschild, S. I.; Haase, S.; Garcia-Marquez, M.; Wennhold, K.; Berlth, F.; Urbanski, A.; Alakus, H.; Schauss, A.; Shimabukuro-Vornhagen, A.; Theurich, S.; Warnecke-Ebertz, U.; Stippel, D. L.; Zippelius, A.; Buttner, R.; Hallek, M.; Holscher, A. H.; Zander, T.; Monig, S. P.; von Bergwelt-Baildon, M.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/33737

Thesis Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

Shekarian, T; Sivado, E; Jallas, AC et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

Authors: Shekarian, T; Sivado, E; Jallas, AC; Depil, S; Kielbassa, J; Janoueix-Lerosey, I; Hutter, G; Goutagny, N; Bergeron, C; Viari, A; Valsesia-Wittmann, S; Caux, C; Marabelle, A

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/40744

Thesis Considerations for the clinical development of immuno-oncology agents in cancer

Pandiella, A; Calvo, E; Moreno, V et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Considerations for the clinical development of immuno-oncology agents in cancer

Authors: Pandiella, A; Calvo, E; Moreno, V; Amir, E; Templeton, A; Ocana, A

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/61130

Thesis Mechanisms of Acquired Resistance to Immune Therapies in Lung Cancer

Robles-Oteiza, Camila · 2021 · Yale University · DOI

Full title: Mechanisms of Acquired Resistance to Immune Therapies in Lung Cancer

Authors: Robles-Oteiza, Camila

Year: 2021

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/400

Thesis The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

El Bairi, K; Haynes, HR; Blackley, E et al. · 2022 · University of Melbourne · DOI

Full title: The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Authors: El Bairi, K; Haynes, HR; Blackley, E; Fineberg, S; Shear, J; Turner, S; de Freitas, JR; Sur, D; Amendola, LC; Gharib, M; Kallala, A; Arun, I; Azmoudeh-Ardalan, F; Fujimoto, L; Sua, LF; Liu, SW; Lien, HC; Kirtani, P; Balancin, M; El Attar, H; Guleria, P; Yang, W; Shash, E; Chen, IC; Bautista, V; Do Prado Moura, JF; Rapoport, BL; Castaneda, C; Spengler, E; Acosta-Haab, G; Frahm, I; Sanchez, J; Castillo, M; Bouchmaa, N; Md Zin, RR; Shui, R; Onyuma, T; Yang, W; Husain, Z; Willard-Gallo, K; Coosemans, A; Perez, EA; Provenzano, E; Ericsson, PG; Richardet, E; Mehrotra, R; Sarancone, S; Ehinger, A; Rimm, DL; Bartlett, JMS; Viale, G; Denkert, C; Hida, AI; Sotiriou, C; Loibl, S; Hewitt, SM; Badve, S; Symmans, WF; Kim, RS; Pruneri, G; Goel, S; Francis, PA; Inurrigarro, G; Yamaguchi, R; Garcia-Rivello, H; Horlings, H; Afqir, S; Salgado, R; Adams, S; Kok, M; Dieci, MV; Michiels, S; Demaria, S; Loi, S; de Freitas, JR; Lien, HC

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/305242

Thesis A phase III, randomized, open-label study (CONTACT-02) of cabozantinib plus atezolizumab versus second novel hormone therapy in patients with metastatic castration-resistant prostate cancer

Agarwal, N; Azad, A; Carles, J et al. · 2022 · University of Melbourne · DOI

Full title: A phase III, randomized, open-label study (CONTACT-02) of cabozantinib plus atezolizumab versus second novel hormone therapy in patients with metastatic castration-resistant prostate cancer

Authors: Agarwal, N; Azad, A; Carles, J; Chowdhury, S; Mcgregor, B; Merseburger, AS; Oudard, S; Saad, F; Soares, A; Benzaghou, F; Kerloeguen, Y; Kimura, A; Mohamed, N; Panneerselvam, A; Wang, F; Pal, S

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/310028

Thesis Profiling the immune landscape in mucinous ovarian carcinoma

Meagher, NS; Hamilton, P; Milne, K et al. · 2023 · University of Melbourne · DOI

Full title: Profiling the immune landscape in mucinous ovarian carcinoma

Authors: Meagher, NS; Hamilton, P; Milne, K; Thornton, S; Harris, B; Weir, A; Alsop, J; Bisinoto, C; Brenton, JD; Brooks-Wilson, A; Chiu, DS; Cushing-Haugen, KL; Fereday, S; Garsed, DW; Gayther, SA; Gentry-Maharaj, A; Gilks, B; Jimenez-Linan, M; Kennedy, CJ; Le, ND; Piskorz, AM; Riggan, MJ; Shah, M; Singh, N; Talhouk, A; Widschwendter, M; Bowtell, DDL; Candido dos Reis, FJ; Cook, LS; Fortner, RT; García, MJ; Harris, HR; Huntsman, DG; Karnezis, AN; Köbel, M; Menon, U; Pharoah, PDP; Doherty, JA; Anglesio, MS; Pike, MC; Pearce, CL; Friedlander, ML; DeFazio, A; Nelson, BH; Ramus, SJ

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/332839

Thesis Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

Virassamy, B; Caramia, F; Savas, P et al. · 2023 · University of Melbourne · DOI

Full title: Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

Authors: Virassamy, B; Caramia, F; Savas, P; Sant, S; Wang, J; Christo, SN; Byrne, A; Clarke, K; Brown, E; Teo, ZL; von Scheidt, B; Freestone, D; Gandolfo, LC; Weber, K; Teply-Szymanski, J; Li, R; Luen, SJ; Denkert, C; Loibl, S; Lucas, O; Swanton, C; Speed, TP; Darcy, PK; Neeson, PJ; Mackay, LK; Loi, S

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/332440

Thesis Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer

Li, R; Sant, S; Brown, E et al. · 2023 · University of Melbourne · DOI

Full title: Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer

Authors: Li, R; Sant, S; Brown, E; Caramia, F; Nikolic, B; Clarke, K; Byrne, A; Lara Gonzalez, LE; Savas, P; Luen, SJ; Teo, ZL; Virassamy, B; Neeson, PJ; Darcy, PK; Loi, S

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/338908

Thesis Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy

Chiu, CY; Chang, JJ; Dantanarayana, AI et al. · 2023 · University of Melbourne · DOI

Full title: Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy

Authors: Chiu, CY; Chang, JJ; Dantanarayana, AI; Solomon, A; Evans, VA; Pascoe, R; Gubser, C; Trautman, L; Fromentin, R; Chomont, N; McMahon, JH; Cameron, PU; Rasmussen, TA; Lewin, SR

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/333694

Thesis Efficacy and safety of novel immune checkpoint inhibitor-based combinations versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer: A network meta-analysis

Yang, C; Xuan, T; Gong, Q et al. · 2024 · University of Melbourne · DOI

Full title: Efficacy and safety of novel immune checkpoint inhibitor-based combinations versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer: A network meta-analysis

Authors: Yang, C; Xuan, T; Gong, Q; Dai, X; Wang, C; Zhang, R; Zhao, W; Wang, J; Yue, W; Li, J

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/351235

Thesis COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer

Segal, NH; Tie, J; Kopetz, S et al. · 2024 · University of Melbourne · DOI

Full title: COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer

Authors: Segal, NH; Tie, J; Kopetz, S; Ducreux, M; Chen, E; Dienstmann, R; Hollebecque, A; Reilley, MJ; Elez, E; Cosaert, J; Cain, J; Soo-Hoo, Y; Hewson, N; Cooper, ZA; Kumar, R; Tabernero, J

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349905

Thesis PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers

Kristeleit, R; Leary, A; Oaknin, A et al. · 2024 · University of Melbourne · DOI

Full title: PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers

Authors: Kristeleit, R; Leary, A; Oaknin, A; Redondo, A; George, A; Chui, S; Seiller, A; Liste-Hermoso, M; Willis, J; Shemesh, CS; Xiao, J; Lin, KK; Molinero, L; Guan, Y; Ray-Coquard, I; Mileshkin, L

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349647

Thesis Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025 · University of Melbourne · DOI

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/357926

Thesis Peripheral Blood T-cell Biomarkers as Predictors of Immunotherapeutic Outcomes in Melanoma

Galloway, Jason · 2024 · The Ohio State University · DOI

Full title: Peripheral Blood T-cell Biomarkers as Predictors of Immunotherapeutic Outcomes in Melanoma

Authors: Galloway, Jason

Year: 2024

Venue: The Ohio State University

DOI: https://kb.osu.edu/handle/1811/105488

Thesis Targeting Myeloid Derived Suppressor Cells enhances the response of immune checkpoint inhibitor

Abood, David · 2022 · The Ohio State University · DOI

Full title: Targeting Myeloid Derived Suppressor Cells enhances the response of immune checkpoint inhibitor

Authors: Abood, David

Year: 2022

Venue: The Ohio State University

DOI: http://hdl.handle.net/1811/102492

Thesis Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Eschweiler, Simon; Clarke, James; Ramirez-Suastegui, Ciro et al. · 2021 · University of Liverpool · DOI

Full title: Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Authors: Eschweiler, Simon; Clarke, James; Ramirez-Suastegui, Ciro; Panwar, Bharat; Madrigal, Ariel; Chee, Serena J; Karydis, Ioannis; Woo, Edwin; Alzetani, Aiman; Elsheikh, Somaia; Hanley, CJ; Thomas, GJ; Friedmann, Peter S; Sanchez-Elsner, Tilman; Ay, Ferhat; Ottensmeier, Christian H; Vijayanand, Pandurangan

Year: 2021

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3145789

Thesis Clinicopathologic and Genomic Landscape of Breast Carcinoma Brain Metastases

Huang, Richard SP; Haberberger, James; McGregor, Kimberly et al. · 2021 · University of Liverpool · DOI

Full title: Clinicopathologic and Genomic Landscape of Breast Carcinoma Brain Metastases

Authors: Huang, Richard SP; Haberberger, James; McGregor, Kimberly; Mata, Douglas A; Decker, Brennan; Hiemenz, Matthew C; Lechpammer, Mirna; Danziger, Natalie; Schiavone, Kelsie; Creeden, James; Graf, Ryon P; Strowd, Roy; Lesser, Glenn J; Razis, Evangelia D; Bartsch, Rupert; Giannoudis, Athina; Bhogal, Talvinder; Lin, Nancy U; Pusztai, Lajos; Ross, Jeffrey S; Palmieri, Carlo; Ramkissoon, Shakti H

Year: 2021

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3126839/1/Breast%20to%20brain%20met%20paper%20Revision%201%20Clean.docx

Thesis NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

Ford, Kirsty; Hanley, Christopher J; Mellone, Massimiliano et al. · 2020 · University of Liverpool · DOI

Full title: NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

Authors: Ford, Kirsty; Hanley, Christopher J; Mellone, Massimiliano; Szyndralewiez, Cedric; Heitz, Freddy; Wiesel, Philippe; Wood, Oliver; Machado, Maria; Lopez, Maria-Antoinette; Ganesan, Anusha-Preethi; Wang, Chuan; Chakravarthy, Ankur; Fenton, Tim R; King, Emma V; Vijayanand, Pandurangan; Ottensmeier, Christian H; Al-Shamkhani, Aymen; Savelyeva, Natalia; Thomas, Gareth J

Year: 2020

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3095444

Thesis Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB-IVM1c melanoma

Malvehy, Josep; Samoylenko, Igor; Schadendorf, Dirk et al. · 2021 · University of Liverpool · DOI

Full title: Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB-IVM1c melanoma

Authors: Malvehy, Josep; Samoylenko, Igor; Schadendorf, Dirk; Gutzmer, Ralf; Grob, Jean-Jacques; Sacco, Joseph J; Gorski, Kevin S; Anderson, Abraham; Pickett, Cheryl A; Liu, Kate; Gogas, Helen

Year: 2021

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3120757

Thesis Improved survival with ipilimumab in patients with metastatic melanoma.

Hodi, FS; O'Day, SJ; McDermott, DF et al. · 2010 · Technical University of Munich (TUM) · DOI

Full title: Improved survival with ipilimumab in patients with metastatic melanoma.

Authors: Hodi, FS;O'Day, SJ;McDermott, DF;Weber, RW;Sosman, JA;Haanen, JB;Gonzalez, R;Robert, C;Schadendorf, D;Hassel, JC;Akerley, W;van den Eertwegh, AJ;Lutzky, J;Lorigan, P;Vaubel, JM;Linette, GP;Hogg, D;Ottensmeier, CH;Lebbe, C;Peschel, C;Quirt, I;Clark, JI;Wolchok, JD;Weber, JS;Tian, J;Yellin, MJ;Nichol, GM;Hoos, A;Urba, WJ

Year: 2010

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1077761

Thesis The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Coen, Oliver; Corrie, Pippa; Marshall, Helen et al. · 2021 · University of Liverpool · DOI

Full title: The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma

Year: 2021

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3145804

Thesis Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI

Zakaria, Rasheed; Jenkinson, Michael D; Radon, Mark et al. · 2023 · University of Liverpool · DOI

Full title: Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI

Authors: Zakaria, Rasheed; Jenkinson, Michael D; Radon, Mark; Das, Kumar; Poptani, Harish; Rathi, Nitika; Rudland, Philip S

Year: 2023

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3171844

Thesis Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

Fennell, Dean A; Ewings, Sean; Ottensmeier, Christian et al. · 2021 · University of Liverpool · DOI

Full title: Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

Authors: Fennell, Dean A; Ewings, Sean; Ottensmeier, Christian; Califano, Raffaele; Hanna, Gerard G; Hill, Kayleigh; Danson, Sarah; Steele, Nicola; Nye, Mavis; Johnson, Lucy; Lord, Joanne; Middleton, Calley; Szlosarek, Peter; Chan, Sam; Gaba, Aarti; Darlison, Liz; Wells-Jordan, Peter; Richards, Cathy; Poile, Charlotte; Lester, Jason F; Griffiths, Gareth

Year: 2021

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3145785/1/Nivolumab%20versus%20placebo%20in%20patients%20with%20relapsed%20malignant%20mesothelioma%20%28CONFIRM%29%20a%20multicentre%2C%20double-blind%2C%20randomised%2C.pdf

Thesis CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity.

Straub, Melanie; Drecoll, Enken; Pfarr, Nicole et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity.

Authors: Straub, Melanie;Drecoll, Enken;Pfarr, Nicole;Weichert, Wilko;Langer, Rupert;Hapfelmeier, Alexander;Götz, Carolin;Wolff, Klaus-Dietrich;Kolk, Andreas;Specht, Katja

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1322244

Thesis Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Weber, Jeffrey S; D'Angelo, Sandra P; Minor, David et al. · 2015 · Technical University of Munich (TUM) · DOI

Full title: Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Authors: Weber, Jeffrey S;D'Angelo, Sandra P;Minor, David;Hodi, F Stephen;Gutzmer, Ralf;Neyns, Bart;Hoeller, Christoph;Khushalani, Nikhil I;Miller, Wilson H;Lao, Christopher D;Linette, Gerald P;Thomas, Luc;Lorigan, Paul;Grossmann, Kenneth F;Hassel, Jessica C;Maio, Michele;Sznol, Mario;Ascierto, Paolo A;Mohr, Peter;Chmielowski, Bartosz;Bryce, Alan;Svane, Inge M;Grob, Jean-Jacques;Krackhardt, Angela M;Horak, Christine;Lambert, Alexandre;Yang, Arvin S;Larkin, James

Year: 2015

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1321975

Thesis Effectiveness and tolerability of ipilimumab: experiences from 198 patients included in a named-patient program in various daily-practice settings and multiple institutions.

Eigentler, Thomas K; Schlaak, Max; Hassel, Jessica C et al. · 2014 · Technical University of Munich (TUM) · DOI

Full title: Effectiveness and tolerability of ipilimumab: experiences from 198 patients included in a named-patient program in various daily-practice settings and multiple institutions.

Authors: Eigentler, Thomas K;Schlaak, Max;Hassel, Jessica C;Loquai, Carmen;Stoffels, Ingo;Gutzmer, Ralf;Pätzold, Sylvie;Mohr, Peter;Keller, Ulrich;Starz, Hans;Ulrich, Jens;Tsianakas, Athanasios;Kähler, Katharina;Hauschild, Axel;Janssen, Eva;Schuler-Thurner, Beatrice;Weide, Benjamin;Garbe, Claus

Year: 2014

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1254432

Thesis PD-1 expression on Melan-A-reactive T cells increases during progression to metastatic disease.

Krönig, H; Julia Falchner, K; Odendahl, M et al. · 2012 · Technical University of Munich (TUM) · DOI

Full title: PD-1 expression on Melan-A-reactive T cells increases during progression to metastatic disease.

Authors: Krönig, H;Julia Falchner, K;Odendahl, M;Brackertz, B;Conrad, H;Muck, D;Hein, R;Blank, C;Peschel, C;Haller, B;Schulz, S;Bernhard, H

Year: 2012

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1181199

Thesis Immune checkpoint therapy for pancreatic cancer.

Johansson, Henrik; Andersson, Roland; Bauden, Monika et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: Immune checkpoint therapy for pancreatic cancer.

Authors: Johansson, Henrik;Andersson, Roland;Bauden, Monika;Hammes, Sarah;Holdenrieder, Stefan;Ansari, Daniel

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1344593

Thesis The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Balermpas, Panagiotis; Rödel, Franz; Krause, Mechthild et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Authors: Balermpas, Panagiotis;Rödel, Franz;Krause, Mechthild;Linge, Annett;Lohaus, Fabian;Baumann, Michael;Tinhofer, Inge;Budach, Volker;Sak, Ali;Stuschke, Martin;Gkika, Eleni;Grosu, Anca-Ligia;Abdollahi, Amir;Debus, Jürgen;Stangl, Stefan;Ganswindt, Ute;Belka, Claus;Pigorsch, Steffi;Multhoff, Gabriele;Combs, Stephanie E;Welz, Stefan;Zips, Daniel;Lim, Su Yin;Rödel, Claus;Fokas, Emmanouil

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1427366

Thesis [Immunotherapy in urothelial carcinoma from a pathologist's perspective].

Erlmeier, Franziska; Steffens, Sandra; Hartmann, Arndt · 2017 · Technical University of Munich (TUM) · DOI

Full title: [Immunotherapy in urothelial carcinoma from a pathologist's perspective].

Authors: Erlmeier, Franziska;Steffens, Sandra;Hartmann, Arndt

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1364859

Thesis The Role of PD-L1 Expression and Intratumoral Lymphocytes in Response to Perioperative Chemotherapy for Urothelial Carcinoma.

Erlmeier, F; Seitz, A K; Hatzichristodoulou, G et al. · 2016 · Technical University of Munich (TUM) · DOI

Full title: The Role of PD-L1 Expression and Intratumoral Lymphocytes in Response to Perioperative Chemotherapy for Urothelial Carcinoma.

Authors: Erlmeier, F;Seitz, A K;Hatzichristodoulou, G;Stecher, L;Retz, M;Gschwend, J E;Weichert, W;Kübler, H R;Horn, T

Year: 2016

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1361275

Thesis Prognostic impact of PD-1 and its ligands in renal cell carcinoma.

Erlmeier, Franziska; Weichert, Wilko; Schrader, Andres Jan et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: Prognostic impact of PD-1 and its ligands in renal cell carcinoma.

Authors: Erlmeier, Franziska;Weichert, Wilko;Schrader, Andres Jan;Autenrieth, Michael;Hartmann, Arndt;Steffens, Sandra;Ivanyi, Philipp

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1359713

Thesis Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma.

Zimmer, Lisa; Apuri, Susmitha; Eroglu, Zeynep et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma.

Authors: Zimmer, Lisa;Apuri, Susmitha;Eroglu, Zeynep;Kottschade, Lisa A;Forschner, Andrea;Gutzmer, Ralf;Schlaak, Max;Heinzerling, Lucie;Krackhardt, Angela M;Loquai, Carmen;Markovic, Svetomir N;Joseph, Richard W;Markey, Kelly;Utikal, Jochen S;Weishaupt, Carsten;Goldinger, Simone M;Sondak, Vernon K;Zager, Jonathan S;Schadendorf, Dirk;Khushalani, Nikhil I

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1439987

Thesis [The role of immunooncology in the treatment of urothelial cancer].

Retz, Margitta; Tauber, Robert; Horn, Thomas · 2017 · Technical University of Munich (TUM) · DOI

Full title: [The role of immunooncology in the treatment of urothelial cancer].

Authors: Retz, Margitta;Tauber, Robert;Horn, Thomas

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1445624

Thesis Checkpoint Inhibition in Head and Neck Cancer: Immune Therapeutic Options, Limitations, and Beyond.

Höchst, Bastian; Knolle, Percy A · 2017 · Technical University of Munich (TUM) · DOI

Full title: Checkpoint Inhibition in Head and Neck Cancer: Immune Therapeutic Options, Limitations, and Beyond.

Authors: Höchst, Bastian;Knolle, Percy A

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1451809

Thesis Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

Cousin, Nikola; Cap, Stefan; Dihr, Manuel et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

Authors: Cousin, Nikola; Cap, Stefan; Dihr, Manuel; Tacconi, Carlotta; Detmar, Michael; Dieterich, Lothar C.

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/500391

Thesis Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus

Toberer, Ferdinand; Winkler, Julia K.; Atienza Fernandez, Leroy et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus

Authors: Toberer, Ferdinand; Winkler, Julia K.; Atienza Fernandez, Leroy; Adams, Lea; Brobeil, Alexander; Tóth, Marcell; Enk, Alexander H.; Becker, Jürgen C.; Lonsdorf, Anke S.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/745322

Thesis Prior corticosteroid treatment alters cPBMC composition and IFNγ response to immunotherapy in canine cancer

Zimmermann, Anna Barbara Emilia; Taskoparan, Betül; Fuchs, Daniel et al. · 2025 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Prior corticosteroid treatment alters cPBMC composition and IFNγ response to immunotherapy in canine cancer

Authors: Zimmermann, Anna Barbara Emilia; Taskoparan, Betül; Fuchs, Daniel; https://orcid.org/0009-0007-1472-4391; Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Maheswaran, Mathischan; Schnyder, Manuela; https://orcid.org/0000-0002-6523-7952; Hartnack, Sonja; https://orcid.org/0000-0002-5757-5708; Rohrer Bley, Carla; https://orcid.org/0000-0002-5733-2722; vom Berg, Johannes; https://orcid.org/0000-0002-4086-1564

Year: 2025

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/230954

Thesis Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Courlet, Perrine; Abler, Daniel; Guidi, Monia et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Authors: Courlet, Perrine; Abler, Daniel; Guidi, Monia; Girard, Pascal; Amato, Federico; Vietti Violi, Naik; Dietz, Matthieu; Guignard, Nicolas; Wicky, Alexandre; Latifyan, Sofiya; De Micheli, Rita; Jreige, Mario; Dromain, Clarisse; Csajka, Chantal; Prior, John O.; Venkatakrishnan, Karthik; Michielin, Olivier; Cuendet, Michel A.; Terranova, Nadia

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/642074

Thesis Cross-reactivity and functionality of approved human immune checkpoint blockers in dogs

Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Ranninger, Elisabeth et al. · 2021 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Cross-reactivity and functionality of approved human immune checkpoint blockers in dogs

Authors: Pantelyushin, Stanislav; https://orcid.org/0000-0002-3490-3860; Ranninger, Elisabeth; https://orcid.org/0000-0002-4345-5203; Guerrera, Diego; https://orcid.org/0000-0002-5323-4447; Hutter, Gregor; Maake, Caroline; https://orcid.org/0000-0003-0378-8203; Markkanen, Enni; https://orcid.org/0000-0001-7780-8233; Bettschart-Wolfensberger, Regula; https://orcid.org/0000-0001-6259-9678; Rohrer Bley, Carla; https://orcid.org/0000-0002-5733-2722; Läubli, Heinz; https://orcid.org/0000-0002-8910-5620; vom Berg, Johannes; https://orcid.org/0000-0002-4086-1564

Year: 2021

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/181371

Thesis Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy

Kobold, Sebastian; Pantelyushin, Stanislav; Rataj, Felicitas et al. · 2018 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy

Authors: Kobold, Sebastian; Pantelyushin, Stanislav; Rataj, Felicitas; vom Berg, Johannes

Year: 2018

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/143367

Thesis Repositioning azelnidipine as a dual inhibitor targeting cd47/sirpα and tigit/pvr pathways for cancer immuno-therapy

Zhou, Xiuman; Jiao, Ling; Qian, Yuzhen et al. · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Repositioning azelnidipine as a dual inhibitor targeting cd47/sirpα and tigit/pvr pathways for cancer immuno-therapy

Authors: Zhou, Xiuman; Jiao, Ling; Qian, Yuzhen; Dong, Qingyu; Sun, Yixuan; Zheng, Wei V.; Zhao, Weishan; Zhai, Weijie; Qiu, Lu; Wu, Yahong; Wang, Hongfei; Gao, Yanfeng; Chen, Junhui

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-110873

Thesis Development of plant-produced bispecific monoclonal antibody targeting PD-L1 and CTLA-4 for cancer immunotherapy

Isip Bulaon, Christine Joy · 2022 · Chulalongkorn University · DOI

Full title: Development of plant-produced bispecific monoclonal antibody targeting PD-L1 and CTLA-4 for cancer immunotherapy

Authors: Isip Bulaon, Christine Joy

Year: 2022

Venue: Chulalongkorn University

DOI: https://digital.car.chula.ac.th/chulaetd/10360

Thesis Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer

Powles, Thomas; Albiges, Laurence; Staehler, Michael et al. · 2018 · Utrecht University · DOI

Full title: Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer

Authors: Powles, Thomas; Albiges, Laurence; Staehler, Michael; Bensalah, Karim; Dabestani, Saeed; Giles, Rachel H.; Hofmann, Fabian; Hora, Milan; Kuczyk, Markus A.; Lam, Thomas B.; Marconi, Lorenzo; Merseburger, Axel S.; Fernández-Pello, Sergio; Tahbaz, Rana; Volpe, Alessandro; Ljungberg, Börje; Bex, Axel

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/364122

Thesis PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications

Luchini, Claudio; Cros, Jerome; Pea, Antonio et al. · 2018 · Utrecht University · DOI

Full title: PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications

Authors: Luchini, Claudio; Cros, Jerome; Pea, Antonio; Pilati, Camilla; Veronese, Nicola; Rusev, Borislav; Capelli, Paola; Mafficini, Andrea; Nottegar, Alessia; Brosens, Lodewijk A.A.; Noë, Michaël; Offerhaus, G. Johan A.; Chianchiano, Peter; Riva, Giulio; Piccoli, Paola; Parolini, Claudia; Malleo, Giuseppe; Lawlor, Rita T.; Corbo, Vincenzo; Sperandio, Nicola; Barbareschi, Mattia; Fassan, Matteo; Cheng, Liang; Wood, Laura D.; Scarpa, Aldo

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/372442

Thesis Efficacy and tolerability of tremelimumab in locally advanced or metastatic urothelial carcinoma patients who have failed first-line platinum-based chemotherapy

Sharma, Padmanee; Sohn, Joohyuk; Shin, Sang Joon et al. · 2020 · Utrecht University · DOI

Full title: Efficacy and tolerability of tremelimumab in locally advanced or metastatic urothelial carcinoma patients who have failed first-line platinum-based chemotherapy

Authors: Sharma, Padmanee; Sohn, Joohyuk; Shin, Sang Joon; Oh, Do Youn; Keam, Bhumsuk; Lee, Hyo Jin; Gizzi, Marco; Kalinka, Ewa; de Vos, Filip Y.F.L.; Ruscica, Dario; Ferro, Salvatore; Xiao, Feng; Baverel, Paul; Chen, Cecil Chi Keung; Asubonteng, Kobby; Morsli, Nassim; Dirix, Luc

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/393984

Thesis High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

Eranki, Avinash; Srinivasan, Priya; Ries, Mario et al. · 2020 · Utrecht University · DOI

Full title: High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

Authors: Eranki, Avinash; Srinivasan, Priya; Ries, Mario; Kim, AeRang; Lazarski, Christopher A; Rossi, Christopher T; Khokhlova, Tatiana D; Wilson, Emmanuel; Knoblach, Susan M; Sharma, Karun V; Wood, Bradford J; Moonen, Chrit; Sandler, Anthony D; Kim, Peter C W

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/394637

Thesis Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung Carcinoma Brain Metastases Receiving Immunotherapy

Hulsbergen, Alexander F C; Mammi, Marco; Nagtegaal, Steven H J et al. · 2020 · Utrecht University · DOI

Full title: Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung Carcinoma Brain Metastases Receiving Immunotherapy

Authors: Hulsbergen, Alexander F C; Mammi, Marco; Nagtegaal, Steven H J; Lak, Asad M; Kavouridis, Vasileios; Smith, Timothy R; Iorgulescu, Julian B; Mekary, Rania A; Verhoeff, Joost J C; Broekman, Marike L D; Phillips, John G

Year: 2020

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/439746

Thesis Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Wienke, Judith; Visser, Lindy L; Kholosy, Waleed M et al. · 2024 · Utrecht University · DOI

Full title: Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/435302

Thesis Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A Cohort Study

van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Aarts, Maureen J B et al. · 2021 · Utrecht University · DOI

Full title: Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease: A Cohort Study

Authors: van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; van Breeschoten, Jesper; van den Eertwegh, Alfonsus J M; B de Groot, Jan Willem; Haanen, John B A G; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; van Zeijl, Michiel C T; Wouters, Michel W J M; Dekkers, Olaf M; Kapiteijn, Ellen

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/442298

Thesis OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors

Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M et al. · 2021 · Utrecht University · DOI

Full title: OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors

Authors: Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M; Olszanski, Anthony J; Spreafico, Anna; Ong, Michael; Chu, Quincy S; Carvajal, Richard D; Trigo, José; Ochoa de Olza, Maria; Provencio, Mariano; De Vos, Filip; de Braud, Filippo; Leong, Stephen; Lathers, Deanne; Wang, Rui; Ravindran, Palani; Feng, Yan; Aanur, Praveen; Melero, Ignacio

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/440999

Thesis Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma

Rossi, Niccolo; Lee, Karla A; Bermudez, Maria V et al. · 2022 · University of Liverpool · DOI

Full title: Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma

Authors: Rossi, Niccolo; Lee, Karla A; Bermudez, Maria V; Visconti, Alessia; Thomas, Andrew Maltez; Bolte, Laura A; Bjork, Johannes R; Ruijter, Laura Kist de; Newton-Bishop, Julia; Harland, Mark; Shaw, Heather M; Harries, Mark; Sacco, Joseph; Board, Ruth; Lorigan, Paul; Vries, Elisabeth GE de; Segata, Nicola; Taams, Leonie; Papa, Sophie; Spector, Tim D; Nathan, Paul; Weersma, Rinse K; Hospers, Geke AP; Fehrmann, Rudolf SN; Bataille, Veronique; Falchi, Mario

Year: 2022

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3167852

Thesis Botensilimab, an Fc-enhanced anti-CTLA-4 antibody, is effective against tumors poorly responsive to conventional immunotherapy

Chand, Dhan; Savitsky, David A; Krishnan, Shanmugarajan et al. · 2024 · Imperial College London · DOI

Full title: Botensilimab, an Fc-enhanced anti-CTLA-4 antibody, is effective against tumors poorly responsive to conventional immunotherapy

Authors: Chand, Dhan; Savitsky, David A; Krishnan, Shanmugarajan; Mednick, Gabriel; Delepine, Chloe; Garcia-Broncano, Pilar; Soh, Kah Teong; Wu, Wei; Wilkens, Margaret K; Udartseva, Olga; Vincent, Sylvia; Joshi, Bishnu; Keith, Justin G; Manrique, Mariana; Marques, Marilyn; Tanne, Antoine; Levey, Daniel L; Han, Haiyong; Ng, Serina; Ridpath, Jackson; Huber, Olivia; Morin, Benjamin; Galand, Claire; Bourdelais, Sean; Gombos, Randi B; Ward, Rebecca; Qin, Yu; Waight, Jeremy D; Costa, Matthew R; Sebastian-Yague, Alvaro; Rudqvist, Nils-Petter; Pupecka-Swider, Malgorzata; Venkatraman, Vignesh; Slee, Andrew; Patel, Jaymin M; Grossman, Joseph E; Wilson, Nicholas S; Von Hoff, Daniel D; Stebbing, Justin; Curiel, Tyler J; Buell, Jennifer S; O'Day, Steven J; Stein, Robert B

Year: 2024

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/39083809

Thesis Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms

Li, Fangda · 2024 · Columbia University · DOI

Full title: Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms

Authors: Li, Fangda

Year: 2024

Venue: Columbia University

DOI: https://doi.org/10.7916/hnwg-dn50

Thesis First-in-Human Study of the Biodistribution and Pharmacokinetics of Zr-89-CX-072, a Novel Immunopet Tracer Based on an Anti-PD-L1 Probody

Kist de Ruijter, Laura; Hooiveld-Noeken, Jahlisa S; Giesen, Danique et al. · 2021 · Utrecht University · DOI

Full title: First-in-Human Study of the Biodistribution and Pharmacokinetics of Zr-89-CX-072, a Novel Immunopet Tracer Based on an Anti-PD-L1 Probody

Authors: Kist de Ruijter, Laura; Hooiveld-Noeken, Jahlisa S; Giesen, Danique; Lub-de Hooge, Marjolijn N; Kok, Iris C; Brouwers, Adrienne H; Elias, Sjoerd G; Nguyen, Margaret T L; Lu, Hong; Gietema, Jourik A; Jalving, Mathilde; de Groot, Derk J A; Vasiljeva, Olga; de Vries, Elisabeth G E

Year: 2021

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/445262

Thesis Optimized sample pre-treatment procedure for the simultaneous UPLC-MS/MS quantification of ipilimumab, nivolumab, and pembrolizumab in human serum

de Jong, Karen A M; Rosing, Hilde; Huitema, Alwin D R et al. · 2022 · Utrecht University · DOI

Full title: Optimized sample pre-treatment procedure for the simultaneous UPLC-MS/MS quantification of ipilimumab, nivolumab, and pembrolizumab in human serum

Authors: de Jong, Karen A M; Rosing, Hilde; Huitema, Alwin D R; Beijnen, Jos H

Year: 2022

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/446714

Thesis ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid

Pluim, Dick; Buitelaar, Pauline; de Jong, Karen A.M. et al. · 2024 · Utrecht University · DOI

Full title: ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid

Authors: Pluim, Dick; Buitelaar, Pauline; de Jong, Karen A.M.; Rosing, Hilde; Brandsma, Dieta; Huitema, Alwin D.R.; Beijnen, Jos H.

Year: 2024

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/453832

Thesis Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Triggers Global Microglia Activation

Yang, Yuanfan · 2022 · Duke University · DOI

Full title: Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Triggers Global Microglia Activation

Authors: Yang, Yuanfan

Year: 2022

Venue: Duke University

DOI: https://hdl.handle.net/10161/25748

Thesis Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Müller, Philipp; Kreuzaler, Matthias; Khan, Tarik et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Authors: Müller, Philipp; Kreuzaler, Matthias; Khan, Tarik; Thommen, Daniela S; Martin, Kea; Glatz, Katharina; Savic, Spasenija; Harbeck, Nadia; Nitz, Ulrike; Gluz, Oleg; von Bergwelt-Baildon, Michael; Kreipe, Hans; Reddy, Sai; Christgen, Matthias; Zippelius, Alfred

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/33196

Thesis Immunophenotyping and neoepitope mapping in relation to immunotherapy of cancer

Skadborg, Signe Koggersbøl · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Immunophenotyping and neoepitope mapping in relation to immunotherapy of cancer

Authors: Skadborg, Signe Koggersbøl

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/05a324d6-c1b9-4fa9-8139-fc0f6769ef39

Thesis The Prostate Cancer Immune Microenvironment, Biomarkers and Therapeutic Intervention

Zhang, Y; Campbell, BK; Stylli, SS et al. · 2022 · University of Melbourne · DOI

Full title: The Prostate Cancer Immune Microenvironment, Biomarkers and Therapeutic Intervention

Authors: Zhang, Y; Campbell, BK; Stylli, SS; Corcoran, NM; Hovens, CM

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/310597

Thesis Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC)

von Witzleben, Adrian; Fehn, Adrian; Grages, Ayla et al. · 2021 · University of Liverpool · DOI

Full title: Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC)

Authors: von Witzleben, Adrian; Fehn, Adrian; Grages, Ayla; Ezic, Jasmin; Jeske, Sandra S; Puntigam, Lisa K; Brunner, Cornelia; Kraus, Johann M; Kestler, Hans A; Doescher, Johannes; Brand, Matthias; Theodoraki, Marie-Nicole; Ottensmeier, Christian H; Hoffmann, Thomas K; Schuler, Patrick J; Laban, Simon

Year: 2021

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3129388

Thesis A randomised phase II study of Nivolumab plus Ipilimumab versus Standard of care in previously untreated and advanced non-clear cell renal cell carcinoma (SUNIFORECAST)

Ahrens, M.; Scheich, S.; Goekbuget, N. et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: A randomised phase II study of Nivolumab plus Ipilimumab versus Standard of care in previously untreated and advanced non-clear cell renal cell carcinoma (SUNIFORECAST)

Authors: Ahrens, M.;Scheich, S.;Goekbuget, N.;Boleti, E.;Gruenwald, V.;Escudier, B.;Goebell, P.;Gschwend, J.;Hartmann, A.;Miller, K.;Burkholder, I.;Schmidinger, M.;Rey, J. P. M.;Bergmann, L.

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1588233

Thesis SUNNIFORECAST - A phase II study of Nivolumab in combination with Ipilimumab versus Standard of care in advanced or metastatic non-clear cell renal cell carcinoma

Scheich, S.; Ahrens, M.; Goekbuget, N. et al. · 2018 · Technical University of Munich (TUM) · DOI

Full title: SUNNIFORECAST - A phase II study of Nivolumab in combination with Ipilimumab versus Standard of care in advanced or metastatic non-clear cell renal cell carcinoma

Authors: Scheich, S.;Ahrens, M.;Goekbuget, N.;Boleti, E.;Burkholder, I;Escudier, B. J.;Goebell, P. J.;Gruenwald, V;Gschwend, J.;Retz, M.;Hartmann, A.;Maroto Rey, J. P.;Miller, K.;Grimm, M. -O;Siemer, S.;Panic, A.;Bergmann, L.

Year: 2018

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1589995

Thesis Consensus paper: current state of first- and second-line therapy in advanced clear-cell renal cell carcinoma.

Goebell, Peter J; Ivanyi, Philipp; Bedke, Jens et al. · 2020 · Technical University of Munich (TUM) · DOI

Full title: Consensus paper: current state of first- and second-line therapy in advanced clear-cell renal cell carcinoma.

Authors: Goebell, Peter J;Ivanyi, Philipp;Bedke, Jens;Bergmann, Lothar;Berthold, Dominik;Boegemann, Martin;Busch, Jonas;Doehn, Christian;Krege, Susanne;Retz, Margitta;Amsberg, Gunhild von;Grimm, Marc-Oliver;Gruenwald, Viktor

Year: 2020

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1617196

Thesis Persistent Cancer Cells Alter Interferon Signaling After Immune Checkpoint Blockade

Ye, Darwin · 2024 · University of Pennsylvania · DOI

Full title: Persistent Cancer Cells Alter Interferon Signaling After Immune Checkpoint Blockade

Authors: Ye, Darwin

Year: 2024

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/59529

Thesis Metabolic regulation of CD8 T cell functions in the tumor microenvironment

Qiu, Jing · 2017 · Washington University in St. Louis · DOI

Full title: Metabolic regulation of CD8 T cell functions in the tumor microenvironment

Authors: Qiu, Jing

Year: 2017

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/1141

Thesis Immunophenotyping and neoepitope mapping in relation to immunotherapy of cancer

Skadborg, Signe Koggersbøl · 2023 · Technical University of Denmark (DTU) · DOI

Full title: Immunophenotyping and neoepitope mapping in relation to immunotherapy of cancer

Authors: Skadborg, Signe Koggersbøl

Year: 2023

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/05a324d6-c1b9-4fa9-8139-fc0f6769ef39

Thesis Evidence of T cell activation and intratumoral nivolumab-presence in glioblastoma patients treated with nivolumab and bevacizumab

Skadborg, Signe; Maarup, Simone; Draghi, Arianna et al. · 2021 · Technical University of Denmark (DTU) · DOI

Full title: Evidence of T cell activation and intratumoral nivolumab-presence in glioblastoma patients treated with nivolumab and bevacizumab

Authors: Skadborg, Signe; Maarup, Simone; Draghi, Arianna; Borch, Annie; Svane, Inge Marie; Hasselbalch, Benedikte; Poulsen, Hans; Lassen, Ulrik; Hadrup, Sine; id_orcid 0000-0002-5937-4344

Year: 2021

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/ba57e796-6aa7-4f43-b0cf-7eda1ad8447b

Thesis A study to investigate the immune response in ovarian cancer patients treated with chemotherapy

Datta, Shreelata · 2018 · Imperial College London · DOI

Full title: A study to investigate the immune response in ovarian cancer patients treated with chemotherapy

Authors: Datta, Shreelata

Year: 2018

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/57030

Thesis A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer

Tietscher, Sandra; Wagner, Johanna; Anzeneder, Tobias et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer

Authors: Tietscher, Sandra; Wagner, Johanna; Anzeneder, Tobias; Langwieder, Claus; Rees, Martin; Sobottka, Bettina; de Souza, Natalie; Bodenmiller, Bernd

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/593768

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2. Data Extraction

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Paper

Type I interferon-mediated tumor immunity and its role in immunotherapy

Yu, Renren, Zhu, Bo, Chen, Degao · 2022

Full title: Type I interferon-mediated tumor immunity and its role in immunotherapy

Authors: Yu, Renren, Zhu, Bo, Chen, Degao

DOI: https://doi.org/10.1007/s00018-022-04219-z

Paper

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Foy, Susan P., Mandl, Stefanie, Cruz, Tracy dela, Cote, Joseph, Gordon, Evan, Trent, Erica, Delcayre, Alain, Breitmeyer, James B., Franzusoff, Alex, Rountree, Ryan B. · 2016

Full title: Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Authors: Foy, Susan P., Mandl, Stefanie, Cruz, Tracy dela, Cote, Joseph, Gordon, Evan, Trent, Erica, Delcayre, Alain, Breitmeyer, James B., Franzusoff, Alex, Rountree, Ryan B.

DOI: https://doi.org/10.1007/s00262-016-1816-7

Paper

Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

Full title: Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition

DOI: https://doi.org/10.1007/s00262-023-03541-0

Paper

Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Sundström, E., Huang, Xueting, Wiemer, Andrew J. · 2025

Full title: Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms

Authors: Sundström, E., Huang, Xueting, Wiemer, Andrew J.

DOI: https://doi.org/10.1007/s00262-025-04128-7

Paper

Mechanisms of resistance to immune checkpoint inhibitors

Jenkins, Russell W., Barbie, David A., Flaherty, Keith T. · 2018

Full title: Mechanisms of resistance to immune checkpoint inhibitors

Authors: Jenkins, Russell W., Barbie, David A., Flaherty, Keith T.

DOI: https://doi.org/10.1038/bjc.2017.434

Paper

T-cell exhaustion in the tumor microenvironment

Jiang, Yuyong, Li, Yongsheng, Zhu, Bo · 2015

Full title: T-cell exhaustion in the tumor microenvironment

Authors: Jiang, Yuyong, Li, Yongsheng, Zhu, Bo

DOI: https://doi.org/10.1038/cddis.2015.162

Paper

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Full title: Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

DOI: https://doi.org/10.1038/ncomms10501

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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Full title: DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

DOI: https://doi.org/10.1038/ncomms15618

Paper

Comprehensive review of targeted therapy for colorectal cancer

Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan · 2020

Full title: Comprehensive review of targeted therapy for colorectal cancer

Authors: Xie, Yuanhong, Chen, Yingxuan, Fang, Jing‐Yuan

DOI: https://doi.org/10.1038/s41392-020-0116-z

Paper

Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail · 2020

Full title: Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Authors: Raskov, Hans, Orhan, Adile, Christensen, Jan Pravsgaard, Gögenür, Ismail

DOI: https://doi.org/10.1038/s41416-020-01048-4

Paper

Neoantigen cancer vaccine augments anti-CTLA-4 efficacy

Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio · 2022

Full title: Neoantigen cancer vaccine augments anti-CTLA-4 efficacy

Authors: Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Conforti, Antonella, Ciliberto, Gennaro, Aurisicchio, Luigi, Palombo, Fabio

DOI: https://doi.org/10.1038/s41541-022-00433-9

Paper

A view on drug resistance in cancer

Vasan, Neil, Baselga, José, Hyman, David M. · 2019

Full title: A view on drug resistance in cancer

Authors: Vasan, Neil, Baselga, José, Hyman, David M.

DOI: https://doi.org/10.1038/s41586-019-1730-1

Paper

Cancer immunotherapy: the beginning of the end of cancer?

Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M. · 2016

Full title: Cancer immunotherapy: the beginning of the end of cancer?

Authors: Farkona, Sofia, Diamandis, Eleftherios P., Blasutig, Ivan M.

DOI: https://doi.org/10.1186/s12916-016-0623-5

Paper

Development of therapeutic antibodies for the treatment of diseases

Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung · 2020

Full title: Development of therapeutic antibodies for the treatment of diseases

Authors: Lu, Ruei‐Min, Hwang, Yu‐Chyi, Liu, I-Ju, Lee, Chi‐Chiu, Tsai, Han-Zen, Li, Hsin‐Jung, Wu, Han‐Chung

DOI: https://doi.org/10.1186/s12929-019-0592-z

Paper

Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia · 2019

Full title: Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

Authors: Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia

DOI: https://doi.org/10.1186/s12943-019-1091-2

Paper

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Yi, Ming; Zheng, Xiaoli; Niu, Mengke et al. · 2022

Full title: Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Authors: Yi, Ming; Zheng, Xiaoli; Niu, Mengke; Zhu, Shuangli; Ge, Hong; Wu, Kongming

DOI: https://doi.org/10.1186/s12943-021-01489-2

Paper

Lung cancer immunotherapy: progress, pitfalls, and promises

Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K. · 2023

Full title: Lung cancer immunotherapy: progress, pitfalls, and promises

Authors: Lahiri, Aritraa, Maji, Avik, Potdar, Pravin D., Singh, Navneet, Parikh, Purvish M., Bisht, Bharti, Mukherjee, Anubhab, Paul, Manash K.

DOI: https://doi.org/10.1186/s12943-023-01740-y

Paper

Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

Full title: Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)

DOI: https://doi.org/10.1186/s12967-018-1568-6

Paper

Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy

Su, Xin, Li, Jian, Xu, Xiao‐Ming, Ye, Yuanyi, Wang, Cailiu, Pang, Guanglong, Liu, Wenxiu, Liu, Ang, Zhao, Changchun, Hao, Xiangyong · 2024

Full title: Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy

Authors: Su, Xin, Li, Jian, Xu, Xiao‐Ming, Ye, Yuanyi, Wang, Cailiu, Pang, Guanglong, Liu, Wenxiu, Liu, Ang, Zhao, Changchun, Hao, Xiangyong

DOI: https://doi.org/10.1186/s12967-024-05552-6

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Gastric cancer treatment: recent progress and future perspectives

Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua · 2023

Full title: Gastric cancer treatment: recent progress and future perspectives

Authors: Guan, Wen‐Long, He, Ye, Xu, Rui‐Hua

DOI: https://doi.org/10.1186/s13045-023-01451-3

Paper

Combination of CTLA-4 and PD-1 blockers for treatment of cancer

Rotte, Anand · 2019

Full title: Combination of CTLA-4 and PD-1 blockers for treatment of cancer

Authors: Rotte, Anand

DOI: https://doi.org/10.1186/s13046-019-1259-z

Paper

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Full title: Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

DOI: https://doi.org/10.1186/s13059-016-1028-7

Paper

Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Álvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, María C., Pérez-Ruiz, Elísabeth, Melero, Ignacio, Berraondo, Pedro · 2019

Full title: Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Authors: Álvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, María C., Pérez-Ruiz, Elísabeth, Melero, Ignacio, Berraondo, Pedro

DOI: https://doi.org/10.15698/cst2019.07.193

Paper

New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Hirsh, Vera · 2017

Full title: New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Authors: Hirsh, Vera

DOI: https://doi.org/10.2147/ott.s104177

Paper

Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui · 2020

Full title: Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer.

Authors: Wang, Shiqiang, Hu, Chongling, Xie, Fei, Liu, Yanhui

DOI: https://doi.org/10.2147/OTT.S235714

Paper

Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng · 2021

Full title: Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Authors: Seesaha, Poshita Kumari, Wang, Kangxin, Wang, Guo-Qun, Cui, Ting-Yun, Zhao, Fengjiao, Pan, Lanlan, Li, Xiangcheng, Shu, Yongqian, Chen, Xiaofeng

DOI: https://doi.org/10.2147/ott.s269671

Paper

Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma

Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi · 2022

Full title: Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma

Authors: Peng, Lijun, Fang, Huapan, Yang, Xiao, Zeng, Xi

DOI: https://doi.org/10.3389/fchem.2022.847621

Paper

Combinatorial Approaches With Checkpoint Inhibitors to Enhance Anti-tumor Immunity

Seliger, Barbara · 2019

Full title: Combinatorial Approaches With Checkpoint Inhibitors to Enhance Anti-tumor Immunity

Authors: Seliger, Barbara

DOI: https://doi.org/10.3389/fimmu.2019.00999

Paper

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping · 2020

Full title: Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Authors: Tang, Yujun, Liu, Jiajia, Zhang, Dingyi, Xu, Zhenghao, Ji, Jinjun, Wen, Chengping

DOI: https://doi.org/10.3389/fimmu.2020.01708

Paper

Immunotherapy in Malignant Pleural Mesothelioma

Gooijer, Cornedine J. de; Borm, Frank J.; Scherpereel, Arnaud et al. · 2020

Full title: Immunotherapy in Malignant Pleural Mesothelioma

Authors: Gooijer, Cornedine J. de; Borm, Frank J.; Scherpereel, Arnaud; Baas, Paul

DOI: https://doi.org/10.3389/fonc.2020.00187

Paper

Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

Full title: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity

DOI: https://doi.org/10.3389/fonc.2020.575737

Paper

Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review

Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu · 2020

Full title: Immune Checkpoint Inhibitors in Advanced Acral Melanoma: A Systematic Review

Authors: Zheng, Qingyue, Li, Jiarui, Zhang, Hanlin, Wang, Yuanzhuo, Zhang, Shu

DOI: https://doi.org/10.3389/fonc.2020.602705

Paper

Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei · 2021

Full title: Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Systemic Treatment Failure—A Retrospective Study

Authors: Wang, Peiliang, Fang, Xiaozhuang, Yin, Tianwen, Tian, Hairong, Yu, Jinming, Teng, Feifei

DOI: https://doi.org/10.3389/fonc.2021.628124

Paper

PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Full title: PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

DOI: https://doi.org/10.3389/fonc.2021.686156

Paper

Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund · 2021

Full title: Systemic Therapy of Metastatic Melanoma: On the Road to Cure

Authors: Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund

DOI: https://doi.org/10.3390/cancers13061430

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How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

Full title: How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma

DOI: https://doi.org/10.3390/cancers13184719

Paper

A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya · 2021

Full title: A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

Authors: Miyasaka, Yuhei, Sato, Hiro, Okano, Naoko, Kubo, Nobuteru, Kawamura, Hidemasa, Ohno, Tatsuya

DOI: https://doi.org/10.3390/cancers14010203

Paper

Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Bryant, Geoffrey, Wang, Lin, Mulholland, David J. · 2017

Full title: Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer

Authors: Bryant, Geoffrey, Wang, Lin, Mulholland, David J.

DOI: https://doi.org/10.3390/ijms18071542

Paper

Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo · 2020

Full title: Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective

Authors: Lavacchi, Daniele, Pellegrini, Elisa, Palmieri, Valeria Emma, Doni, Laura, Mela, Marinella Micol, Maida, Fabrizio Di, Amedei, Amedeo, Pillozzi, Serena, Carini, Marco, Antonuzzo, Lorenzo

DOI: https://doi.org/10.3390/ijms21134691

Paper

Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni · 2021

Full title: Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice

Authors: Nowosielska, Ewa M., Cheda, Aneta, Pocięgiel, Mateusz, Cheda, Łukasz, Szymański, Paweł, Więdłocha, Antoni

DOI: https://doi.org/10.3390/ijms22126309

Paper

A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H. · 2020

Full title: A Review of Cancer Immunotherapy: From the Past, to the Present, to the Future

Authors: Esfahani, Khashayar, Roudaia, Liya, Buhlaiga, Najwa, Rincón, Sonia V. del, Papneja, Neha, Miller, Wilson H.

DOI: https://doi.org/10.3747/co.27.5223

Paper

Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Li, Shan, Shen, Liangfang · 2020

Full title: Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists

Authors: Li, Shan, Shen, Liangfang

DOI: https://doi.org/10.7150/jca.44408

Thesis

Part A - PD-1/PD-L1 blockade in cancer immunotherapy/ Part B - Evaluation of PD-1/PD-L1 immune checkpoint inhibitors in a luciferase-reporter cell-based assay

Peredo Aguilar, Maria Azucena · 2023

Full title: Part A - PD-1/PD-L1 blockade in cancer immunotherapy/ Part B - Evaluation of PD-1/PD-L1 immune checkpoint inhibitors in a luciferase-reporter cell-based assay

Authors: Peredo Aguilar, Maria Azucena

DOI: https://eprints.nottingham.ac.uk/76035/1/MariaAzucenaAguilar_MResDissertation2023.pdf

Thesis

Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP] et al. · 2025

Full title: Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Authors: Talavera Guillén, Noelia C. [UNESP]; Barboza de Nardi, Andrigo [UNESP]; Noleto de Paiva, Felipe [UNESP]; Dias, Queila Cristina; Pinheiro Fantinatti, Alexandra; Fávaro, Wagner José

DOI: http://dx.doi.org/10.3390/ani13121888

Thesis

In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression

Yaegashi, Lygia Bertalha; Baldavira, Camila Machado; Prieto, Tabatha Gutierrez et al. · 2022

Full title: In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression

DOI: http://dx.doi.org/10.3389/fimmu.2021.714230

Thesis

PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

Melaiu, O; Mina, M; Chierici, M et al. · 2017

Full title: PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma

DOI: http://hdl.handle.net/1959.4/unsworks_44362

Thesis

Major milestones in translational oncology.

Dragani, Tommaso A; Castells, Antoni; Kulasingam, Vathany et al. · 2016

Full title: Major milestones in translational oncology.

Authors: Dragani, Tommaso A; Castells, Antoni; Kulasingam, Vathany; Diamandis, Eleftherios P; Earl, Helena; Iams, Wade T; Lovly, Christine M; Sedelaar, JP Michiel; Schalken, Jack A

DOI: https://www.repository.cam.ac.uk/handle/1810/260591

Thesis

Spotlight on landmark oncology trials: the latest evidence and novel trial designs.

Earl, Helena; Molica, Stefano; Rutkowski, Piotr · 2017

Full title: Spotlight on landmark oncology trials: the latest evidence and novel trial designs.

Authors: Earl, Helena; Molica, Stefano; Rutkowski, Piotr

DOI: https://www.repository.cam.ac.uk/handle/1810/264598

Thesis

Immunotherapy for Renal Cancer: Sequencing and Combinations

Stewart, GD; De Santis, M; Escudier, B et al. · 2017

Full title: Immunotherapy for Renal Cancer: Sequencing and Combinations

Authors: Stewart, GD; De Santis, M; Escudier, B; Powles, T; Sonpavde, G

DOI: https://www.repository.cam.ac.uk/handle/1810/265376

Thesis

Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Lim, SY; Lee, JH; Welsh, SJ et al. · 2017

Full title: Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Authors: Lim, SY; Lee, JH; Welsh, SJ; Ahn, SB; Breen, E; Khan, A ; https://orcid.org/0000-0002-5072-378X; Carlino, MS; Menzies, AM; Kefford, RF; Scolyer, RA; Long, GV; Rizos, H

DOI: http://hdl.handle.net/1959.4/unsworks_79785

Thesis

Immune profiling of pediatric solid tumors

Terry, RL; https://orcid.org/0000-0002-6260-7372; Meyran, D et al. · 2020

Full title: Immune profiling of pediatric solid tumors

DOI: http://hdl.handle.net/1959.4/unsworks_80081

Thesis

VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1): An Open Label Randomized Controlled Phase-2-Study.

Smyth, Elizabeth; Knödler, Maren; Giraut, Anne et al. · 2020

Authors: Smyth, Elizabeth; Knödler, Maren; Giraut, Anne; Mauer, Murielle; Nilsson, Magnus; Van Grieken, Nicole; Wagner, Anna Dorothea; Moehler, Markus; Lordick, Florian

DOI: https://www.repository.cam.ac.uk/handle/1810/303757

Thesis

Medical treatment of renal cancer: new horizons.

Greef, Basma; Eisen, Tim · 2020

Full title: Medical treatment of renal cancer: new horizons.

Authors: Greef, Basma; Eisen, Tim

DOI: https://www.repository.cam.ac.uk/handle/1810/303908

Thesis

Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review.

Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth · 2022

Full title: Immune checkpoint inhibitors in resectable gastroesophageal cancers - a review.

Authors: Mukherjee, Sarbajit; Parmar, Kanak; Smyth, Elizabeth

DOI: https://www.repository.cam.ac.uk/handle/1810/343973

Thesis

75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

Stewart, Professor Grant; Jones, James, Dr.; Warren, Anne, Dr. et al. · 2024

Full title: 75 WIRE: Window of Opportunity Clinical Trials Platform for Evaluation of Novel Treatments Strategies in Renal Cell Cancer

DOI: https://www.repository.cam.ac.uk/handle/1810/372324

Thesis

Enhancing Cancer Treatment through Combination Therapies

Mohajershojai, Tabassom · 2024

Full title: Enhancing Cancer Treatment through Combination Therapies

Authors: Mohajershojai, Tabassom

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-530645

Thesis

Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Iyer, Nivedha Srikanth · 2024

Full title: Cathepsin-S as a Target in Pancreatic Ductal Adenocarcinoma - Investigation and Therapeutic Implication

Authors: Iyer, Nivedha Srikanth

DOI: https://escholarship.org/uc/item/5m579278

Thesis

Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Wein, L; Luen, SJ; Savas, P et al. · 2020

Full title: Checkpoint blockade in the treatment of breast cancer: Current status and future directions

Authors: Wein, L; Luen, SJ; Savas, P; Salgado, R; Loi, S

DOI: https://hdl.handle.net/11343/255249

Thesis

Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Meehan, K; Leslie, C; Lucas, M et al. · 2020

Full title: Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease

Authors: Meehan, K; Leslie, C; Lucas, M; Jacques, A; Mirzai, B; Lim, J; Bulsara, M; Khan, Y; Wong, NC; Solomon, B; Sader, C; Friedland, P; Mir Arnau, G; Semple, T; Lim, AM

DOI: https://hdl.handle.net/11343/246366

Thesis

An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Bottai, G; Raschioni, C; Losurdo, A et al. · 2020

Full title: An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers

Authors: Bottai, G; Raschioni, C; Losurdo, A; Di Tommaso, L; Tinterri, C; Torrisi, R; Reis-Filho, JS; Roncalli, M; Sotiriou, C; Santoro, A; Mantovani, A; Loi, S; Santarpia, L

DOI: https://hdl.handle.net/11343/257795

Thesis

Autoantibodies may predict immune-related toxicity: Results from a phase I study of intralesional Bacillus Calmette-Guérin followed by ipilimumab in patients with advanced metastatic melanoma

Duarte, JDG; Parakh, S; Andrews, MC et al. · 2020

Authors: Duarte, JDG; Parakh, S; Andrews, MC; Woods, K; Pasam, A; Tutuka, C; Ostrouska, S; Blackburn, JM; Behren, A; Cebon, J

DOI: https://hdl.handle.net/11343/256187

Thesis

Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2021

Full title: Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

DOI: https://hdl.handle.net/11343/259450

Thesis

Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

Duchnowska, R; Peksa, R; Radecka, B et al. · 2021

Full title: Immune response in breast cancer brain metastases and their microenvironment: The role of the PD-1/PD-L axis

DOI: https://hdl.handle.net/11343/260579

Thesis

SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Galligan, A; Iravani, A; Lasocki, A et al. · 2021

Full title: SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Authors: Galligan, A; Iravani, A; Lasocki, A; Wallace, R; Weppler, A; Au-Yeung, G; Sachithanandan, N; Chiang, CY; Wentworth, J; Colman, PG; Kay, TW; Krishnamurthy, B; Sandhu, S

DOI: https://hdl.handle.net/11343/273859

Thesis

Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Ascierto, PA; McArthur, GA · 2020

Full title: Checkpoint inhibitors in melanoma and early phase development in solid tumors: What's the future?

Authors: Ascierto, PA; McArthur, GA

DOI: https://hdl.handle.net/11343/256879

Thesis

Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

Bowyer, S; Prithviraj, P; Lorigan, P et al. · 2020

Full title: Reply to 'Comment on 'Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy''

DOI: https://hdl.handle.net/11343/258389

Thesis

Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Chew, HY; Dolcetti, R; Simpson, F · 2021

Full title: Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Authors: Chew, HY; Dolcetti, R; Simpson, F

DOI: https://hdl.handle.net/11343/275929

Thesis

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Saleh, R; Taha, RZ; Toor, SM et al. · 2021

Full title: Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Authors: Saleh, R; Taha, RZ; Toor, SM; Sasidharan Nair, V; Murshed, K; Khawar, M; Al-Dhaheri, M; Petkar, MA; Abu Nada, M; Elkord, E

DOI: https://hdl.handle.net/11343/277749

Thesis

Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Saleh, R; Toor, SM; Al-Ali, D et al. · 2021

Full title: Blockade of pd-1, pd-l1, and tim-3 altered distinct immune-and cancer-related signaling pathways in the transcriptome of human breast cancer explants

Authors: Saleh, R; Toor, SM; Al-Ali, D; Sasidharan Nair, V; Elkord, E

DOI: https://hdl.handle.net/11343/277709

Thesis

Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

Saleh, R; Toor, SM; Sasidharan Nair, V et al. · 2021

Full title: Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

Authors: Saleh, R; Toor, SM; Sasidharan Nair, V; Elkord, E

DOI: https://hdl.handle.net/11343/277715

Thesis

Real-world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab

Mohr, P; Ascierto, P; Arance, A et al. · 2021

Full title: Real-world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab

Authors: Mohr, P; Ascierto, P; Arance, A; McArthur, G; Hernaez, A; Kaskel, P; Shinde, R; Stevinson, K

DOI: https://hdl.handle.net/11343/293838

Thesis

Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Hilbers, ML; Dimitriou, F; Lau, P et al. · 2021

Full title: Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastases

Authors: Hilbers, ML; Dimitriou, F; Lau, P; Bhave, P; McArthur, GA; Zimmer, L; Kudura, K; Gérard, CL; Levesque, MP; Michielin, O; Dummer, R; Cheng, PF; Mangana, J

DOI: https://hdl.handle.net/11343/289654

Thesis

Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Ahern, E; Solomon, BJ; Hui, R et al. · 2021

Full title: Neoadjuvant immunotherapy for non-small cell lung cancer: Right drugs, right patient, right time?

Authors: Ahern, E; Solomon, BJ; Hui, R; Pavlakis, N; O'Byrne, K; Hughes, BGM

DOI: https://hdl.handle.net/11343/287197

Thesis

Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

Fennell, DA; Ewings, S; Ottensmeier, C et al. · 2022

Full title: Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

DOI: https://hdl.handle.net/11343/296717

Thesis

Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Klein, O; Kee, D; Gao, B et al. · 2022

Full title: Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial

Authors: Klein, O; Kee, D; Gao, B; Markman, B; Da Gama Duarte, J; Quigley, L; Jackett, L; Linklater, R; Strickland, A; Scott, C; Mileshkin, L; Palmer, J; Carlino, M; Behren, A; Cebon, J

DOI: https://hdl.handle.net/11343/296391

Thesis

Immune checkpoint blockade in renal cell carcinoma

Rappold, PM; Silagy, AW; Kotecha, RR et al. · 2022

Full title: Immune checkpoint blockade in renal cell carcinoma

Authors: Rappold, PM; Silagy, AW; Kotecha, RR; Hakimi, AA

DOI: https://hdl.handle.net/11343/298242

Thesis

Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

Lau, PKH; Feran, B; Smith, L et al. · 2022

Full title: Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

DOI: https://hdl.handle.net/11343/296832

Thesis

Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Klein, O; Senko, C; Carlino, MS et al. · 2022

Full title: Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup analysis of CA209-538

Authors: Klein, O; Senko, C; Carlino, MS; Markman, B; Jackett, L; Gao, B; Lum, C; Kee, D; Behren, A; Palmer, J; Cebon, J

DOI: https://hdl.handle.net/11343/304665

Thesis

Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion

Tobias, Joshua (Medical University of Vienna); Wiedermann, Ursula (Medical University of Vienna); Högler, Sandra (University of Veterinary Medicine Vienna) et al. · 2023

Full title: Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion

DOI: https://phaidra.vetmeduni.ac.at/o:3001

Thesis

Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

Ferris, Robert L; Spanos, William C; Leidner, Rom et al. · 2021

Full title: Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial

DOI: https://dspace.library.uu.nl/handle/1874/442886

Thesis

Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

van Not, Olivier J; Verheijden, Rik J; van den Eertwegh, Alfonsus J M et al. · 2022

Full title: Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

DOI: https://dspace.library.uu.nl/handle/1874/447350

Thesis

Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

Lim, Michael; Weller, Michael; Idbaih, Ahmed et al. · 2022

Full title: Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

DOI: https://dspace.library.uu.nl/handle/1874/446311

Thesis

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis

CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

Ter Maat, Laurens S; van Duin, Isabella A J; Elias, Sjoerd G et al. · 2023

Full title: CT radiomics compared to a clinical model for predicting checkpoint inhibitor treatment outcomes in patients with advanced melanoma

DOI: https://dspace.library.uu.nl/handle/1874/448890

Thesis

The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive et al. · 2024

Full title: The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?

Authors: Di Giacomo, Anna Maria; Lahn, Michael; Center München, Munich, Germany, Comprehensive; Fox, Bernard; Ibrahim, Ramy; Sharma, Padmanee; Allison, James P.; Maio, Michele

DOI: https://dspace.library.uu.nl/handle/1874/454126

Thesis

Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

van Duin, Isabella A.J.; Schuiveling, Mark; ter Maat, Laurens S. et al. · 2024

Full title: Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma

DOI: https://dspace.library.uu.nl/handle/1874/454114

Thesis

Immunosurveillance in clinical cancer management

Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M. et al. · 2024

Full title: Immunosurveillance in clinical cancer management

Authors: Kroemer, Guido; Chan, Timothy A.; Eggermont, Alexander M.M.; Galluzzi, Lorenzo

DOI: https://dspace.library.uu.nl/handle/1874/454448

Thesis

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

Lin, Lishi; Houwink, Aletta P.I.; van Dieren, Jolanda M. et al. · 2024

Full title: Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors

DOI: https://dspace.library.uu.nl/handle/1874/455323

Thesis

Efficacy and safety in early-phase clinical trials for refractory colorectal cancer: A meta-analysis

Smabers, Lidwien P; Huismans, Maarten A; van Nieuwenhuijzen, Niels et al. · 2024

Full title: Efficacy and safety in early-phase clinical trials for refractory colorectal cancer: A meta-analysis

Authors: Smabers, Lidwien P; Huismans, Maarten A; van Nieuwenhuijzen, Niels; Minnema, Monique C; Kranenburg, Onno; Koopman, Miriam; Snippert, Hugo J G; May, Anne M; Roodhart, Jeanine M L

DOI: https://dspace.library.uu.nl/handle/1874/458345

Thesis

Five latent factors underlie response to immunotherapy

Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A. et al. · 2024

Full title: Five latent factors underlie response to immunotherapy

DOI: https://dspace.library.uu.nl/handle/1874/458268

Thesis

Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors.

Nasca, Vincenzo; Zhao, Joseph; Ros, Javier et al. · 2025

Full title: Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors.

DOI: https://dspace.library.uu.nl/handle/1874/460579

Thesis

The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

Ascierto, Paolo A.; Blank, Christian; Eggermont, Alexander M. et al. · 2023

Full title: The “Great Debate” at Melanoma Bridge 2022, Naples, December 1st–3rd, 2022

DOI: https://dspace.library.uu.nl/handle/1874/459059

Thesis

Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

Bhatia, Shailender; Topalian, Suzanne L; Sharfman, William et al. · 2025

Full title: Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study

DOI: https://dspace.library.uu.nl/handle/1874/460578

Thesis

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Cochran, Jennifer R; Moynihan, Kelly Dare; Opel, Cary Francis et al. · 2017

Full title: Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

DOI: http://hdl.handle.net/1721.1/109826

Thesis

Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

Shi, Alvin; Kasumova, Gyulnara G; Michaud, William A et al. · 2022

Full title: Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

DOI: https://hdl.handle.net/1721.1/132258.2

Thesis

Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Regev, Aviv · 2020

Full title: Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Authors: Regev, Aviv

DOI: https://hdl.handle.net/1721.1/125032

Thesis

Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E. et al. · 2020

Full title: Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Authors: Ricciuti, Biagio; Kravets, Sasha; Dahlberg, Suzanne E.; Umeton, Renato; Albayrak, Adem; Subegdjo, Safiya J.; Johnson, Bruce E.; Nishino, Mizuki; Sholl, Lynette M.; Awad, Mark M.

DOI: https://hdl.handle.net/1721.1/128646

Thesis

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Spranger-Zimmermann, Stefani · 2020

Full title: Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

Authors: Spranger-Zimmermann, Stefani

DOI: https://hdl.handle.net/1721.1/126367

Thesis

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Prakadan, Sanjay M; Alvarez-Breckenridge, Christopher A; Markson, Samuel C et al. · 2022

Full title: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

DOI: https://hdl.handle.net/1721.1/141282

Thesis

Context Dependent Effects of TIGIT Expression on NK Cells Demonstrate Intra-Tumoral TIGIT Blocking Immunotherapy to be Superior to Systemic Injections in Cross-Species Models of Soft Tissue and Osteosarcoma

Lammers, Marshall · 2025

Authors: Lammers, Marshall

DOI: https://escholarship.org/uc/item/62w1z16d

Thesis

Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

Bhave, P; Pallan, L; Long, GV et al. · 2022

Full title: Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

DOI: https://hdl.handle.net/11343/304521

Thesis

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma

Kennedy, OJ; Kicinski, M; Valpione, S et al. · 2022

Full title: Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma

DOI: https://hdl.handle.net/11343/322129

Thesis

Insights into Cancer Immunotherapies: Recent Breakthroughs, Opportunities, and Challenges

Pappas, EG; Kershaw, MH; Slaney, CY · 2023

Full title: Insights into Cancer Immunotherapies: Recent Breakthroughs, Opportunities, and Challenges

Authors: Pappas, EG; Kershaw, MH; Slaney, CY

DOI: https://hdl.handle.net/11343/327345

Thesis

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Bhave, P; Ahmed, T; Lo, SN et al. · 2022

Full title: Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

DOI: https://hdl.handle.net/11343/316921

Thesis

IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

Dunkel, IJ; Cohen, K; Foreman, NK et al. · 2022

Full title: IMMU-08. Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: efficacy, safety, biomarker, and pharmacokinetic results from Checkmate 908

DOI: https://hdl.handle.net/11343/318235

Thesis

Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer

Augustine, T; John, P; Friedman, T et al. · 2023

Full title: Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer

Authors: Augustine, T; John, P; Friedman, T; Jiffry, J; Guzik, H; Mannan, R; Gupta, R; Delano, C; Mariadason, JM; Zang, X; Maitra, R; Goel, S

DOI: https://hdl.handle.net/11343/335344

Thesis

A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma

Voss, MH; Azad, AA; Hansen, AR et al. · 2023

Full title: A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma

Authors: Voss, MH; Azad, AA; Hansen, AR; Gray, JE; Welsh, SJ; Song, X; Kuziora, M; Meinecke, L; Blando, J; Achour, I; Wang, Y; Walcott, FL; Oosting, SF

DOI: https://hdl.handle.net/11343/335610

Thesis

First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

Kim, TW; Burris, HA; de Miguel Luken, MJ et al. · 2022

Full title: First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

DOI: https://hdl.handle.net/11343/320417

Thesis

Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.

Zhai, T; Wang, C; Xu, Y et al. · 2022

Authors: Zhai, T; Wang, C; Xu, Y; Huang, W; Yuan, Z; Wang, T; Dai, S; Peng, S; Pang, T; Jiang, W; Huang, Y; Zou, Y; Xu, Y; Sun, J; Gong, X; Zhang, J; Tsun, A; Li, B; Miao, X

DOI: https://hdl.handle.net/11343/316255

Thesis

63P Treatment-free survival (TFS) in patients (pts) with mNSCLC treated with 1L nivolumab (NIVO) + ipilimumab (IPI) + 2 cycles of chemotherapy (chemo) vs chemo alone (4 cycles) in CheckMate (CM) 9LA

Reck, M; Regan, M; Carbone, DP et al. · 2024

Authors: Reck, M; Regan, M; Carbone, DP; Lu, S; John, T; Penrod, J; Li, J; Yuan, Y; Mahmood, J; Lee, A; Eccles, L; Ray, S; Paz-Ares, L

DOI: https://hdl.handle.net/11343/351905

Thesis

Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Carbone, DP; Ciuleanu, TE; Schenker, M et al. · 2024

DOI: https://hdl.handle.net/11343/352762

Thesis

Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Zhang, J; Liang, W; Liang, H et al. · 2024

Full title: Endpoint surrogacy in oncological randomized controlled trials with immunotherapies: a systematic review of trial-level and arm-level meta-analyses

Authors: Zhang, J; Liang, W; Liang, H; Wang, X; He, J

DOI: https://hdl.handle.net/11343/350365

Thesis

A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

Conduit, C; Davis, ID; Goh, JC et al. · 2024

Full title: A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non-clear-cell renal cell carcinoma

DOI: https://hdl.handle.net/11343/339980

Thesis

A gut microbial signature for combination immune checkpoint blockade across cancer types

Gunjur, A; Shao, Y; Rozday, T et al. · 2024

Full title: A gut microbial signature for combination immune checkpoint blockade across cancer types

DOI: https://hdl.handle.net/11343/353256

Thesis

First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

Hegewisch-Becker, S; Mendez, G; Chao, J et al. · 2025

Full title: First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study

DOI: https://hdl.handle.net/11343/358332

Thesis

A non-randomised open-label exploratory ‘window of opportunity’ study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer

Roth, S; Wilson, KC; Ramsay, RG et al. · 2025

Full title: A non-randomised open-label exploratory ‘window of opportunity’ study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer

DOI: https://hdl.handle.net/11343/359449

Thesis

Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025

Full title: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review: Epidemiology

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

DOI: https://hdl.handle.net/11343/359086

Thesis

Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Jayathilaka, B; Mian, F; Franchini, F et al. · 2025

Full title: Correction to: Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

Authors: Jayathilaka, B; Mian, F; Franchini, F; Au-Yeung, G; IJzerman, M

DOI: https://hdl.handle.net/11343/360026

Thesis

Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander et al. · 2020

Full title: Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

Authors: Liebler, Daniel C; Holzer, Timothy R; Haragan, Alexander; Morrison, Ryan D; O’Neill Reising, Leslie; Ackermann, Bradley L; Fill, Jeff A; Schade, Andrew E; Gruver, Aaron M

DOI: https://livrepository.liverpool.ac.uk/3091687/1/Analysis.pdf

Thesis

Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Arriola, Edurne; Wheater, Matthew; Galea, Ian et al. · 2016

Full title: Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Thesis

NOVEL MONO-, BI- AND TRI-SPECIFIC IMMUNOMODULATORY ANTIBODIES FOR CANCER THERAPY AND TOOLS FOR OTHER THERAPEUTIC AND DIAGNOSTIC APPLICATIONS

RAPUANO LEMBO, ROSA · 2025

Full title: NOVEL MONO-, BI- AND TRI-SPECIFIC IMMUNOMODULATORY ANTIBODIES FOR CANCER THERAPY AND TOOLS FOR OTHER THERAPEUTIC AND DIAGNOSTIC APPLICATIONS

Authors: RAPUANO LEMBO, ROSA

DOI: http://dx.doi.org/10.13130/rapuano-lembo-rosa_phd2025-12-19

Thesis

The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Kuchroo, Juhi · 2020

Full title: The role of PD-1 in modulating T cell responses in autoimmunity and cancer

Authors: Kuchroo, Juhi

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365910

Thesis

Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Mangsbo, Sara · 2009

Full title: Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

Authors: Mangsbo, Sara

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110147

Thesis

Antibody-based immunotherapy of cancer : From optimization to novel approaches

van Hooren, Luuk · 2018

Full title: Antibody-based immunotherapy of cancer : From optimization to novel approaches

Authors: van Hooren, Luuk

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342799

Thesis

A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Heinhuis, Kimberley Marga · 2020

Full title: A quest through diagnostics and predictive tools and the exploration of new treatment strategies in clinical trials to improve cancer therapy

Authors: Heinhuis, Kimberley Marga

DOI: https://dspace.library.uu.nl/handle/1874/400086

Thesis

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, William A; Lambert, Laurens J; Ely, Zackery A et al. · 2022

Full title: The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

DOI: https://hdl.handle.net/1721.1/146821

Thesis

Overall Survival of Elderly Patients with Non-Small Cell Lung Cancer Treated with Programmed Death-1 (PD-1) Inhibitors and Microbiome Altering Medications: A Retrospective Analysis Using the SEER-Medicare Database

Hughes, Valerie · 2023

Authors: Hughes, Valerie

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1692293042036511

Thesis

Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Taggart, David John · 2016

Full title: Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Authors: Taggart, David John

DOI: https://etheses.whiterose.ac.uk/id/eprint/16116/1/Thesis%20.pdf

Thesis

Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

Chryplewicz, Agnieszka; Scotton, Julie; Tichet, Melanie et al. · 2022

Full title: Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

Authors: Chryplewicz, Agnieszka; Scotton, Julie; Tichet, Melanie; Zomer, Anoek; Shchors, Ksenya; Joyce, Johanna A.; Homicsko, Krisztian; Hanahan, Douglas

DOI: https://infoscience.epfl.ch/handle/20.500.14299/192476

Thesis

Estimating Heterogeneity of Harm-Benefit Balance of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

Heyward, James Shivers · 2025

Full title: Estimating Heterogeneity of Harm-Benefit Balance of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

Authors: Heyward, James Shivers

DOI: https://jscholarship.library.jhu.edu/handle/1774.2/70166

Thesis

Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

Ascierto, PA; Atkins, M; Bifulco, C et al. · 2021

Full title: Future perspectives in melanoma research: Meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014

DOI: https://hdl.handle.net/11343/262597

Thesis

Relevance of blood-based biomarkers for prediction of response to chemotherapy and prognosis in lung cancer patients

Krüger, Kimberly · 2021

Full title: Relevance of blood-based biomarkers for prediction of response to chemotherapy and prognosis in lung cancer patients

Authors: Krüger, Kimberly

DOI: https://mediatum.ub.tum.de/1574259

Thesis

Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Pühl, Miriam · 2024

Full title: Multiple gene editing of T Cell inhibitory receptors via CRISPR/Cas9 in EL4 cells

Authors: Pühl, Miriam

DOI: https://refubium.fu-berlin.de/handle/fub188/40924

Thesis

TRIPLE IMMUNOTHERAPY TO OVERCOME IMMUNE EVASION BY TUMOR IN A MELANOMA MOUSE MODEL

Jallad, Mary-Ann · 2020

Full title: TRIPLE IMMUNOTHERAPY TO OVERCOME IMMUNE EVASION BY TUMOR IN A MELANOMA MOUSE MODEL

Authors: Jallad, Mary-Ann

DOI: http://hdl.handle.net/10938/22166

Thesis

Immune Checkpoint Molecule Expression in Canine Lymphoma and Canine Reactive Lymphoid Hyperplasia

Clothier, Stacy Lauren · 2021

Full title: Immune Checkpoint Molecule Expression in Canine Lymphoma and Canine Reactive Lymphoid Hyperplasia

Authors: Clothier, Stacy Lauren

DOI: http://hdl.handle.net/10919/103200

Thesis

Monitorización Inmunológica en Pacientes Tratados con Inhibidores de Puntos de Control Inmunitario: Identificación de Biomarcadores para la Predicción de Eventos Adversos Inmunomediados

Alserawan De Lamo, Leticia · 2024

Authors: Alserawan De Lamo, Leticia

DOI: http://hdl.handle.net/10803/692979

Thesis

Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta · 2019

Full title: Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review

Authors: van Bussel, Mark T J; Beijnen, Jos H; Brandsma, Dieta

DOI: https://dspace.library.uu.nl/handle/1874/390030

Thesis

Biomarkers in cancer immunotherapy

Schumacher, Ton N; Kesmir, Can; van Buuren, Marit M · 2015

Full title: Biomarkers in cancer immunotherapy

Authors: Schumacher, Ton N; Kesmir, Can; van Buuren, Marit M

DOI: https://dspace.library.uu.nl/handle/1874/320977

Thesis

Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

Verheijden, Rik J; May, Anne M; Blank, Christian U et al. · 2020

Full title: Association of anti-TNF with decreased survival in steroid refractory ipilimumab and anti-PD1 treated patients in the Dutch Melanoma Treatment Registry

DOI: https://dspace.library.uu.nl/handle/1874/396657

Thesis

A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Arnaud-Coffin, P; Maillet, D; Gan, HK et al. · 2021

Full title: A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors

Authors: Arnaud-Coffin, P; Maillet, D; Gan, HK; Stelmes, J-J; You, B; Dalle, S; Peron, J

DOI: https://hdl.handle.net/11343/285412

Thesis

CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Wang, J; Li, X; Xiao, G et al. · 2024

Full title: CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors

Authors: Wang, J; Li, X; Xiao, G; Desai, J; Frentzas, S; Wang, ZM; Xia, Y; Li, B

DOI: https://hdl.handle.net/11343/350752

Thesis

Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Sandin, Linda · 2013

Full title: Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

Authors: Sandin, Linda

DOI: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210080

Thesis

Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Veinalde, Rūta · 2017

Full title: Unraveling Determinants of Efficacy in Measles Immunovirotherapy

Authors: Veinalde, Rūta

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/23094/1/R.Veinalde_Thesis_print.pdf

Thesis

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Küçükköse, Emre; Heesters, Balthasar A.; Villaudy, Julien et al. · 2022

Full title: Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

DOI: https://dspace.library.uu.nl/handle/1874/426611

Thesis

F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Wong, A; Callahan, J; Keyaerts, M et al. · 2020

Full title: F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Authors: Wong, A; Callahan, J; Keyaerts, M; Neyns, B; Mangana, J; Aberle, S; Herschtal, A; Fullerton, S; Milne, D; Iravani, A; McArthur, GA; Hicks, RJ

DOI: https://hdl.handle.net/11343/246372

Thesis

Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Verbrugge, I; Galli, M; Smyth, MJ et al. · 2021

Full title: Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

Authors: Verbrugge, I; Galli, M; Smyth, MJ; Johnstone, RW; Haynes, NM

DOI: https://hdl.handle.net/11343/265284

Thesis

PHASE 1 STUDY OF AMG 160, A HALF-LIFE EXTENDED BITE® (BISPECIFIC T-CELL ENGAGER) THERAPY TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN, IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

Dorff, T; Rettig, M; Machiels, J-P et al. · 2021

Authors: Dorff, T; Rettig, M; Machiels, J-P; Lolkema, M; Autio, K; Greil, R; Rottey, S; Adra, N; Salvati, M; Poon, S; Tan, D; Jurida, G; Kouros-Mehr, H; Fizazi, K; Tran, B; Horvath, L

DOI: https://hdl.handle.net/11343/273969

Thesis

IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

Giuffrida, L; Sek, K; Henderson, MA et al. · 2023

Full title: IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

DOI: https://hdl.handle.net/11343/331896

Thesis

NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers

Brooker, RC; Schache, AG; Sacco, JJ · 2021

Full title: NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers

Authors: Brooker, RC; Schache, AG; Sacco, JJ

DOI: https://livrepository.liverpool.ac.uk/3101657/1/Brooker%202020%20BJOMS_NICO%20short%20communication.pdf

Thesis

Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Guillén, Noelia Carolina Talavera [UNESP] · 2023

Full title: Avaliação da expressão da via pd-1/pdl-1 e das proteínas ctla-4, rank-rank-l e ifn-γ em mastocitomas cutâneos de alto grau em cães: novas perspectivas de uso da imunoterapia

Authors: Guillén, Noelia Carolina Talavera [UNESP]

DOI: http://hdl.handle.net/11449/239302

Thesis

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Arce Vargas, Frederick; Furness, Andrew JS; Litchfield, Kevin et al. · 2018

Full title: Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

DOI: https://www.repository.cam.ac.uk/handle/1810/277642

Thesis

Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.

Meade, Angela; Frangou, Elena; Choodari-Oskooei, Babak et al. · 2025

Full title: Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.

DOI: https://www.repository.cam.ac.uk/handle/1810/378106

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· 2025

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· 2009

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· 2025

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· 2015

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· 2014

Full title: us-2014358066-a1

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· 2015

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· 2015

Full title: us-2015125463-a1

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· 2015

Full title: us-2015320999-a1

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· 2015

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· 2021

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· 2021

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Evidence For Pd 1 Pd L1 Combination Immunotherapie

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