Evidence Analysis Of Popular Biohacker Longevity I

Paper Epigenetic clock and methylation studies in vervet monkeys

Jasinska, Anna J.; Haghani, Amin; Zoller, Joseph A. et al. · 2021 · GeroScience · DOI

Full title: Epigenetic clock and methylation studies in vervet monkeys

Authors: Jasinska, Anna J.; Haghani, Amin; Zoller, Joseph A.; Li, Caesar Z.; Arneson, A; Ernst, Jason; Kavanagh, Kylie; Jorgensen, Matthew J.; Mattison, Julie A.; Wojta, Kevin; Choi, Oi‐Wa; DeYoung, Joseph; Li, Xin‐Min; Rao, Andrew W.; Coppola, Giovanni; Freimer, Nelson B.; Woods, Roger P.; Horvath, Steve

Year: 2021

Venue: GeroScience

Paper The PICLS high-throughput screening method for agents extending cellular longevity identifies 2,5-anhydro-D-mannitol as novel anti-aging compound.

Alfatah, Mohammad; Eisenhaber, Frank · 2023 · GeroScience · DOI

Full title: The PICLS high-throughput screening method for agents extending cellular longevity identifies 2,5-anhydro-D-mannitol as novel anti-aging compound.

Authors: Alfatah, Mohammad; Eisenhaber, Frank

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00598-0

Paper Endpoints for geroscience clinical trials: health outcomes, biomarkers, and biologic age

Cummings, Steven R.; Kritchevsky, Stephen B. · 2022 · GeroScience · DOI

Full title: Endpoints for geroscience clinical trials: health outcomes, biomarkers, and biologic age

Authors: Cummings, Steven R.; Kritchevsky, Stephen B.

Year: 2022

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00671-8

Paper Epigenetic clock and methylation studies in the rhesus macaque

Horvath, Steve; Zoller, Joseph A.; Haghani, Amin et al. · 2021 · GeroScience · DOI

Full title: Epigenetic clock and methylation studies in the rhesus macaque

Authors: Horvath, Steve; Zoller, Joseph A.; Haghani, Amin; Jasinska, Anna J.; Raj, Ken; Breeze, Charles E.; Ernst, Jason; Vaughan, Kelli L.; Mattison, Julie A.

Year: 2021

Venue: GeroScience

DOI: https://doi.org/10.54254/2753-8818/2025.au25075

Paper Diabetes mellitus correlates with increased biological age as indicated by clinical biomarkers

Bahour, Nadine; Cortez, Briana N.; Pan, Hui et al. · 2021 · GeroScience · DOI

Full title: Diabetes mellitus correlates with increased biological age as indicated by clinical biomarkers

Authors: Bahour, Nadine; Cortez, Briana N.; Pan, Hui; Shah, Hetal; Doria, Alessandro; Aguayo‐Mazzucato, Cristina

Year: 2021

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-021-00469-0

Paper Reversal of biological age in multiple rat organs by young porcine plasma fraction

Horvath, Steve; Singh, Kavita; Raj, Ken et al. · 2023 · GeroScience · DOI

Full title: Reversal of biological age in multiple rat organs by young porcine plasma fraction

Authors: Horvath, Steve; Singh, Kavita; Raj, Ken; Khairnar, Shraddha I.; Sanghavi, Akshay; Shrivastava, Agnivesh; Zoller, Joseph A.; Li, Caesar Z.; Hereñú, Claudia Beatriz; Canatelli-Mallat, Martina; Lehmann, Marianne; Habazin, Siniša; Novokmet, Mislav; Vučković, Frano; Woods, Leah C. Solberg; Martinez, Angel Garcia; Wang, Tengfei; Chiavellini, Priscila; Levine, Andrew J.; Chen, Hao; Brooke, Robert T.; Gordevičius, Juozas; Lauc, Gordan; Goya, Rodolfo G.; Katcher, Harold L.

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00980-6

Paper In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Venz, Richard; Goyala, Anita; Soto-Gamez, Abel et al. · 2023 · GeroScience · DOI

Full title: In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Authors: Venz, Richard; Goyala, Anita; Soto-Gamez, Abel; Yenice, Tugce; Demaria, Marco; Ewald, Collin Y.

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00909-z

Paper Potential geroprotectors - from the banch to the clinic

A. A. Moskalev · 2023 · Биохимия · DOI

Full title: Potential geroprotectors - from the banch to the clinic

Authors: A. A. Moskalev

Year: 2023

Venue: Биохимия

DOI: https://doi.org/10.31857/s0320972523110064

Paper Targeting the Mitochondria-Proteostasis Axis to Delay Aging.

Zimmermann, Andreas; Madreiter-Sokolowski, Corina; Stryeck, Sarah et al. · 2021 · Frontiers in cell and developmental biology · DOI

Full title: Targeting the Mitochondria-Proteostasis Axis to Delay Aging.

Authors: Zimmermann, Andreas; Madreiter-Sokolowski, Corina; Stryeck, Sarah; Abdellatif, Mahmoud

Year: 2021

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2021.656201

Paper Geroprotectors and Skeletal Health: Beyond the Headlines.

Rayson, Alexandra; Boudiffa, Maya; Naveed, Maneeha et al. · 2022 · Frontiers in cell and developmental biology · DOI

Full title: Geroprotectors and Skeletal Health: Beyond the Headlines.

Authors: Rayson, Alexandra; Boudiffa, Maya; Naveed, Maneeha; Griffin, Jon; Dall'Ara, Enrico; Bellantuono, Ilaria

Year: 2022

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2022.682045

Paper Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells.

Acar, Mustafa Burak; Ayaz-Güner, Şerife; Gunaydin, Zeynep et al. · 2021 · Frontiers in bioengineering and biotechnology · DOI

Full title: Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells.

Authors: Acar, Mustafa Burak; Ayaz-Güner, Şerife; Gunaydin, Zeynep; Karakukcu, Musa; Peluso, Gianfranco; Di Bernardo, Giovanni; Özcan, Servet; Galderisi, Umberto

Year: 2021

Venue: Frontiers in bioengineering and biotechnology

DOI: https://doi.org/10.3389/fbioe.2021.730813

Paper Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy

A. Bareja; David E. Lee; James P. White · 2019 · Front. Cell Dev. Biol. · DOI

Full title: Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy

Authors: A. Bareja; David E. Lee; James P. White

Year: 2019

Venue: Front. Cell Dev. Biol.

DOI: https://doi.org/10.3389/fcell.2019.00183

Paper New Perspectives for Fisetin

G. Grynkiewicz; O. Demchuk · 2019 · Frontiers in Chemistry · DOI

Full title: New Perspectives for Fisetin

Authors: G. Grynkiewicz; O. Demchuk

Year: 2019

Venue: Frontiers in Chemistry

DOI: https://doi.org/10.3389/fchem.2019.00697

Paper From theories of aging to anti-aging interventions.

Moskalev, Alexey A; Pasyukova, Elena G · 2014 · Frontiers in genetics · DOI

Full title: From theories of aging to anti-aging interventions.

Authors: Moskalev, Alexey A; Pasyukova, Elena G

Year: 2014

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2014.00276

Paper Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs.

Zhavoronkov, Alex; Buzdin, Anton A; Garazha, Andrey V et al. · 2014 · Frontiers in genetics · DOI

Full title: Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs.

Authors: Zhavoronkov, Alex; Buzdin, Anton A; Garazha, Andrey V; Borisov, Nikolay M; Moskalev, Alexey A

Year: 2014

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2014.00049

Paper Aging-modulating treatments: from reductionism to a system-oriented perspective.

Vaiserman, Alexander M · 2014 · Frontiers in genetics · DOI

Full title: Aging-modulating treatments: from reductionism to a system-oriented perspective.

Authors: Vaiserman, Alexander M

Year: 2014

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2014.00446

Paper Drugs against metabolic diseases as potential senotherapeutics for aging-related respiratory diseases.

Matsubayashi, Sachi; Ito, Saburo; Araya, Jun et al. · 2023 · Frontiers in endocrinology · DOI

Full title: Drugs against metabolic diseases as potential senotherapeutics for aging-related respiratory diseases.

Authors: Matsubayashi, Sachi; Ito, Saburo; Araya, Jun; Kuwano, Kazuyoshi

Year: 2023

Venue: Frontiers in endocrinology

DOI: https://doi.org/10.3389/fendo.2023.1079626

Paper Editorial: Proceedings of the 3rd International Conference on Genetics of Aging and Longevity.

Pasyukova, Elena G; Moskalev, Alexey · 2016 · Frontiers in genetics · DOI

Full title: Editorial: Proceedings of the 3rd International Conference on Genetics of Aging and Longevity.

Authors: Pasyukova, Elena G; Moskalev, Alexey

Year: 2016

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2016.00119

Paper Hacking Aging: A Strategy to Use Big Data From Medical Studies to Extend Human Life.

Fedichev, Peter O · 2018 · Frontiers in genetics · DOI

Full title: Hacking Aging: A Strategy to Use Big Data From Medical Studies to Extend Human Life.

Authors: Fedichev, Peter O

Year: 2018

Venue: Frontiers in genetics

DOI: https://doi.org/10.3389/fgene.2018.00483

Paper A comprehensive overview of cellular senescence from 1990 to 2021: A machine learning-based bibliometric analysis.

Li, Chan; Liu, Zhaoya; Shi, Ruizheng · 2023 · Frontiers in medicine · DOI

Full title: A comprehensive overview of cellular senescence from 1990 to 2021: A machine learning-based bibliometric analysis.

Authors: Li, Chan; Liu, Zhaoya; Shi, Ruizheng

Year: 2023

Venue: Frontiers in medicine

DOI: https://doi.org/10.3389/fmed.2023.1072359

Paper Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

M. B. Birkisdóttir; Lisanne J. van’t Sant; R. Brandt et al. · 2023 · Frontiers in Aging Neuroscience · DOI

Full title: Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

Authors: M. B. Birkisdóttir; Lisanne J. van’t Sant; R. Brandt; S. Barnhoorn; J. Hoeijmakers; W. Vermeij; D. Jaarsma

Year: 2023

Venue: Frontiers in Aging Neuroscience

DOI: https://doi.org/10.3389/fnagi.2022.1095801

Paper Nicotinamide Riboside Vitamin B3 Mitigated C26 Adenocarcinoma–Induced Cancer Cachexia

Park, Jong Min; Han, Young Min; Lee, Ho Jae et al. · 2021 · Frontiers in Pharmacology · DOI

Full title: Nicotinamide Riboside Vitamin B3 Mitigated C26 Adenocarcinoma–Induced Cancer Cachexia

Authors: Park, Jong Min; Han, Young Min; Lee, Ho Jae; Park, Yong Jin; Hahm, Ki Baik

Year: 2021

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2021.665493

Paper Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management

Liu, Pan; Li, Yun; Ma, Lina · 2021 · Frontiers in Nutrition · DOI

Full title: Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management

Authors: Liu, Pan; Li, Yun; Ma, Lina

Year: 2021

Venue: Frontiers in Nutrition

DOI: https://doi.org/10.3389/fnut.2021.731356

Paper Gene expression changes in cerebellum induced by dietary restriction

Lisanne J. van’t Sant; M. B. Birkisdóttir; R. A. Ozinga et al. · 2023 · Frontiers in Molecular Neuroscience · DOI

Full title: Gene expression changes in cerebellum induced by dietary restriction

Authors: Lisanne J. van’t Sant; M. B. Birkisdóttir; R. A. Ozinga; Á. Gyenis; J. Hoeijmakers; W. Vermeij; D. Jaarsma

Year: 2023

Venue: Frontiers in Molecular Neuroscience

DOI: https://doi.org/10.3389/fnmol.2023.1185665

Paper The Impacts of Short-Term NMN Supplementation on Serum Metabolism, Fecal Microbiota, and Telomere Length in Pre-Aging Phase

Niu, Kai‐Min; Bao, Tongtong; Gao, Lumin et al. · 2021 · Frontiers in Nutrition · DOI

Full title: The Impacts of Short-Term NMN Supplementation on Serum Metabolism, Fecal Microbiota, and Telomere Length in Pre-Aging Phase

Authors: Niu, Kai‐Min; Bao, Tongtong; Gao, Lumin; Ru, Meng; Li, Yumeng; Jiang, Liang; Ye, Changming; Wang, Shujin; Wu, Xin

Year: 2021

Venue: Frontiers in Nutrition

DOI: https://doi.org/10.3389/fnut.2021.756243

Paper Geroprotective and Radioprotective Activity of Quercetin, (-)-Epicatechin, and Ibuprofen in Drosophila melanogaster.

Proshkina, Ekaterina; Lashmanova, Ekaterina; Dobrovolskaya, Eugenia et al. · 2016 · Frontiers in pharmacology · DOI

Full title: Geroprotective and Radioprotective Activity of Quercetin, (-)-Epicatechin, and Ibuprofen in Drosophila melanogaster.

Authors: Proshkina, Ekaterina; Lashmanova, Ekaterina; Dobrovolskaya, Eugenia; Zemskaya, Nadezhda; Kudryavtseva, Anna; Shaposhnikov, Mikhail; Moskalev, Alexey

Year: 2016

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2016.00505

Paper The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans.

Lashmanova, Ekaterina; Zemskaya, Nadezhda; Proshkina, Ekaterina et al. · 2017 · Frontiers in pharmacology · DOI

Full title: The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans.

Authors: Lashmanova, Ekaterina; Zemskaya, Nadezhda; Proshkina, Ekaterina; Kudryavtseva, Anna; Volosnikova, Marina; Marusich, Elena; Leonov, Sergey; Zhavoronkov, Alex; Moskalev, Alexey

Year: 2017

Venue: Frontiers in pharmacology

DOI: https://doi.org/10.3389/fphar.2017.00884

Paper The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

Titorenko, Vladimir I; Harkness, Troy A A · 2012 · Frontiers in physiology · DOI

Full title: The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

Authors: Titorenko, Vladimir I; Harkness, Troy A A

Year: 2012

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2012.00419

Paper Atorvastatin Therapy Modulates Telomerase Activity in Patients Free of Atherosclerotic Cardiovascular Diseases

I. Strazhesko; O. Tkacheva; D. Akasheva et al. · 2016 · Frontiers in Pharmacology · DOI

Full title: Atorvastatin Therapy Modulates Telomerase Activity in Patients Free of Atherosclerotic Cardiovascular Diseases

Authors: I. Strazhesko; O. Tkacheva; D. Akasheva; E. Dudinskaya; E. Plokhova; V. S. Pykhtina; A. S. Kruglikova; N. V. Kokshagina; N. Sharashkina; M. Agaltsov; D. Kashtanova; V. Vygodin; I. Ozerova; D. Skvortsov; D. Vasilkova; S. Boytsov

Year: 2016

Venue: Frontiers in Pharmacology

DOI: https://doi.org/10.3389/fphar.2016.00347

Paper Dynamic Aging: Channeled Through Microenvironment.

Tan, Qing; Liang, Na; Zhang, Xiaoqian et al. · 2021 · Frontiers in physiology · DOI

Full title: Dynamic Aging: Channeled Through Microenvironment.

Authors: Tan, Qing; Liang, Na; Zhang, Xiaoqian; Li, Jun

Year: 2021

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2021.702276

Paper Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill.

Ewald, Collin Y · 2021 · Frontiers in aging · DOI

Full title: Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill.

Authors: Ewald, Collin Y

Year: 2021

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2021.741843

Paper The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C et al. · 2022 · Frontiers in aging · DOI

Full title: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

Authors: Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C; Barnhoorn, Sander; van Vliet, Nicole; van Dijk, Claire; Nagarajah, Bhawani; Imholz, Sandra; van Oostrom, Conny T; Reiling, Erwin; Gyenis, Ákos; Mastroberardino, Pier G; Jaarsma, Dick; van Steeg, Harry; Hoeijmakers, Jan H J; Dollé, Martijn E T; Vermeij, Wilbert P

Year: 2022

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2022.1005322

Paper Recent Advances in Studying Age-Associated Lipids Alterations and Dietary Interventions in Mammals

Gille, Benedikt; Galuska, Christina E.; Fuchs, Beate et al. · 2021 · Frontiers in Aging · DOI

Full title: Recent Advances in Studying Age-Associated Lipids Alterations and Dietary Interventions in Mammals

Authors: Gille, Benedikt; Galuska, Christina E.; Fuchs, Beate; Peleg, Shahaf

Year: 2021

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2021.773795

Paper Clinical Trials Targeting Aging

J. Nielsen; Daniela Bakula; M. Scheibye-Knudsen · 2022 · Frontiers in Aging · DOI

Full title: Clinical Trials Targeting Aging

Authors: J. Nielsen; Daniela Bakula; M. Scheibye-Knudsen

Year: 2022

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2022.820215

Paper Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C et al. · 2022 · Frontiers in aging · DOI

Full title: Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

Year: 2022

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2022.1086552

Paper Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review.

Knufinke, Marie; MacArthur, Michael R; Ewald, Collin Y et al. · 2023 · Frontiers in aging · DOI

Full title: Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review.

Authors: Knufinke, Marie; MacArthur, Michael R; Ewald, Collin Y; Mitchell, Sarah J

Year: 2023

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2023.1172789

Paper Considerations Regarding Public Use of Longevity Interventions.

Liu, Yasmine J; McIntyre, Rebecca L; Janssens, Georges E · 2022 · Frontiers in aging · DOI

Full title: Considerations Regarding Public Use of Longevity Interventions.

Authors: Liu, Yasmine J; McIntyre, Rebecca L; Janssens, Georges E

Year: 2022

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2022.903049

Paper The hallmarks of aging as a conceptual framework for health and longevity research

Tartiere, Antonio G.; Freije, José M.P.; López-Otı́n, Carlos · 2024 · Frontiers in Aging · DOI

Full title: The hallmarks of aging as a conceptual framework for health and longevity research

Authors: Tartiere, Antonio G.; Freije, José M.P.; López-Otı́n, Carlos

Year: 2024

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2024.1334261

Paper Premature aging in genetic diseases: what conclusions can be drawn for physiological aging

Milosic, Filip; Hengstschläger, Markus; Osmanagic‐Myers, Selma · 2024 · Frontiers in Aging · DOI

Full title: Premature aging in genetic diseases: what conclusions can be drawn for physiological aging

Authors: Milosic, Filip; Hengstschläger, Markus; Osmanagic‐Myers, Selma

Year: 2024

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2023.1327833

Paper Toward precision longevity: aging interventions in the single-cell atlas era.

Chen, Jason B; Wang, Miranda C; Gong, Shangyu et al. · 2025 · Frontiers in aging · DOI

Full title: Toward precision longevity: aging interventions in the single-cell atlas era.

Authors: Chen, Jason B; Wang, Miranda C; Gong, Shangyu; Li, Hongjie

Year: 2025

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2025.1674112

Paper Life Extension by Anti-Aging Drugs: Hormetic Explanation?

A. Vaiserman · 2008 · Journal of Pharmacology and Toxicology · DOI

Full title: Life Extension by Anti-Aging Drugs: Hormetic Explanation?

Authors: A. Vaiserman

Year: 2008

Venue: Journal of Pharmacology and Toxicology

DOI: https://doi.org/10.3844/ajptsp.2008.14.18

Paper Calorie Restriction Modulates Gene Expression of Il19 and Il24 of during Renal Aging.

S. Noh; Hyun Woo Kim; Seungwoo Kim et al. · 2025 · Annals of Geriatric Medicine and Research · DOI

Full title: Calorie Restriction Modulates Gene Expression of Il19 and Il24 of during Renal Aging.

Authors: S. Noh; Hyun Woo Kim; Seungwoo Kim; Mi K. Kim; Byung Pal Yu; K. Chung; Hae Young Chung

Year: 2025

Venue: Annals of Geriatric Medicine and Research

DOI: https://doi.org/10.4235/agmr.25.0103

Paper Anti-aging strategies for dogs: current insights and future directions

Jae Ryong Lim; Jee Hyeon Yoon; Ho Jae Han · 2025 · Journal of Veterinary Sciences · DOI

Full title: Anti-aging strategies for dogs: current insights and future directions

Authors: Jae Ryong Lim; Jee Hyeon Yoon; Ho Jae Han

Year: 2025

Venue: Journal of Veterinary Sciences

DOI: https://doi.org/10.4142/jvs.25202

Paper Berberine Attenuated Aging-Accelerating Effect of High Temperature in Drosophila Model

Navrotskaya, Valeriya; Oxenkrug, Gregory F.; Vorobyova, Lyudmila et al. · 2014 · American Journal of Plant Sciences · DOI

Full title: Berberine Attenuated Aging-Accelerating Effect of High Temperature in Drosophila Model

Authors: Navrotskaya, Valeriya; Oxenkrug, Gregory F.; Vorobyova, Lyudmila; Summergrad, Paul

Year: 2014

Venue: American Journal of Plant Sciences

DOI: https://doi.org/10.4236/ajps.2014.53037

Paper Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice.

Fuellen, Georg; Kulaga, Anton; Lobentanzer, Sebastian et al. · 2025 · Ageing research reviews · DOI

Full title: Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice.

Authors: Fuellen, Georg; Kulaga, Anton; Lobentanzer, Sebastian; Unfried, Maximilian; Avelar, Roberto A; Palmer, Daniel; Kennedy, Brian K

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102617

Paper Dynamical Network Stability Analysis of Multiple Biological Ages Provides a Framework for Understanding the Aging Process

G. Pridham; A. Rutenberg · 2023 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Dynamical Network Stability Analysis of Multiple Biological Ages Provides a Framework for Understanding the Aging Process

Authors: G. Pridham; A. Rutenberg

Year: 2023

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glae021

Paper Therapeutic hypercapnia. Review

Denis Tolstun; K. Muradian; V. Bezrukov · 2022 · Issue 3 2022 · DOI

Full title: Therapeutic hypercapnia. Review

Authors: Denis Tolstun; K. Muradian; V. Bezrukov

Year: 2022

Venue: Issue 3 2022

DOI: https://doi.org/10.47855/al9020-2022-3-5

Paper The Anti-Aging Effect of Metformin on C. elegans Through Idha-1, an Isocitrate Dehydrogenase in the TCA Cycle

Song Zhu · 2025 · Theoretical and Natural Science · DOI

Full title: The Anti-Aging Effect of Metformin on C. elegans Through Idha-1, an Isocitrate Dehydrogenase in the TCA Cycle

Authors: Song Zhu

Year: 2025

Venue: Theoretical and Natural Science

Paper Anti-senescence effects of 4-methoxychalcone and 4-bromo-4'-methoxychalcone on human endothelial cells.

Tien, Xin-Yi; Lee, Yean Kee; Wong, Pooi-Fong et al. · 2024 · Drug discoveries & therapeutics · DOI

Full title: Anti-senescence effects of 4-methoxychalcone and 4-bromo-4'-methoxychalcone on human endothelial cells.

Authors: Tien, Xin-Yi; Lee, Yean Kee; Wong, Pooi-Fong; Khor, Yi-Sheng; Murugan, Dharmani Devi; Abdullah, Iskandar

Year: 2024

Venue: Drug discoveries & therapeutics

DOI: https://doi.org/10.5582/ddt.2024.01034

Paper Zebrafish Aging Models and Possible Interventions

Dilan Celebi-Birand; Begun Erbaba; A. T. Ozdemir et al. · 2018 · Recent Advances in Zebrafish Researches · DOI

Full title: Zebrafish Aging Models and Possible Interventions

Authors: Dilan Celebi-Birand; Begun Erbaba; A. T. Ozdemir; HulusiKafaligonul; M. Adams

Year: 2018

Venue: Recent Advances in Zebrafish Researches

DOI: https://doi.org/10.5772/intechopen.75554

Paper Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics.

Fielder, Edward P; Ishaq, Abbas; Low, Evon et al. · 2024 · Aging biology · DOI

Full title: Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics.

Authors: Fielder, Edward P; Ishaq, Abbas; Low, Evon; Laws, Joseph A; Calista, Aisha; Castle, Jemma; von Zglinicki, Thomas; Miwa, Satomi

Year: 2024

Venue: Aging biology

DOI: https://doi.org/10.59368/agingbio.20240022

Paper Genetic diversity estimates for the Caenorhabditis Intervention Testing Program screening panel.

Teterina, Anastasia A; Coleman-Hulbert, Anna L; Banse, Stephen A et al. · 2022 · microPublication biology · DOI

Full title: Genetic diversity estimates for the Caenorhabditis Intervention Testing Program screening panel.

Authors: Teterina, Anastasia A; Coleman-Hulbert, Anna L; Banse, Stephen A; Willis, John H; Perez, Viviana I; Lithgow, Gordon J; Driscoll, Monica; Phillips, Patrick C

Year: 2022

Venue: microPublication biology

DOI: https://doi.org/10.17912/micropub.biology.000518

Paper How to save Medicare: the anti-aging remedy.

Blagosklonny, Mikhail V · 2012 · Aging · DOI

Full title: How to save Medicare: the anti-aging remedy.

Authors: Blagosklonny, Mikhail V

Year: 2012

Venue: Aging

DOI: https://doi.org/10.18632/aging.100479

Paper Chain-breaking antioxidant activity of reduced forms of mitochondria-targeted quinones, a novel type of geroprotectors.

Roginsky, Vitaly A; Tashlitsky, Vadim N; Skulachev, Vladimir P · 2009 · Aging · DOI

Full title: Chain-breaking antioxidant activity of reduced forms of mitochondria-targeted quinones, a novel type of geroprotectors.

Authors: Roginsky, Vitaly A; Tashlitsky, Vadim N; Skulachev, Vladimir P

Year: 2009

Venue: Aging

DOI: https://doi.org/10.18632/aging.100049

Paper Regulation of the mitochondrial transition pore: impact on mammalian aging

H. Osiewacz · 2011 · Aging · DOI

Full title: Regulation of the mitochondrial transition pore: impact on mammalian aging

Authors: H. Osiewacz

Year: 2011

Venue: Aging

DOI: https://doi.org/10.18632/aging.100259

Paper Targeting neuroinflammation - a potential for anti-aging interventions.

Cady, Gillian; Sadagurski, Marianna · 2017 · Aging · DOI

Full title: Targeting neuroinflammation - a potential for anti-aging interventions.

Authors: Cady, Gillian; Sadagurski, Marianna

Year: 2017

Venue: Aging

DOI: https://doi.org/10.18632/aging.101296

Paper Inflammaging: disturbed interplay between autophagy and inflammasomes

Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu · 2012 · Aging · DOI

Full title: Inflammaging: disturbed interplay between autophagy and inflammasomes

Authors: Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu

Year: 2012

Venue: Aging

DOI: https://doi.org/10.18632/aging.100444

Paper New comparative genomics approach reveals a conserved health span signature across species

Antosh, Michael; Fox, David J.; Helfand, Stephen L. et al. · 2011 · Aging · DOI

Full title: New comparative genomics approach reveals a conserved health span signature across species

Authors: Antosh, Michael; Fox, David J.; Helfand, Stephen L.; Cooper, Leon N.; Neretti, Nicola

Year: 2011

Venue: Aging

DOI: https://doi.org/10.18632/aging.100342

Paper Fish oil supplements, longevity and aging.

de Magalhães, João Pedro; Müller, Michael; Rainger, G Ed et al. · 2016 · Aging · DOI

Full title: Fish oil supplements, longevity and aging.

Authors: de Magalhães, João Pedro; Müller, Michael; Rainger, G Ed; Steegenga, Wilma

Year: 2016

Venue: Aging

DOI: https://doi.org/10.18632/aging.101021

Paper A review of the biomedical innovations for healthy longevity

A. Moskalev; V. Anisimov; A. Aliper et al. · 2017 · Aging · DOI

Full title: A review of the biomedical innovations for healthy longevity

Authors: A. Moskalev; V. Anisimov; A. Aliper; Artem V. Artemov; K. Asadullah; Daniel W Belsky; A. Baranova; Aubrey de Grey; Vishwa Deep Dixit; Édouard Debonneuil; E. Dobrovolskaya; P. Fedichev; Alexander Fedintsev; V. Fraifeld; C. Franceschi; Rosie Freer; T. Fülöp; J. Feige; D. Gems; V. Gladyshev; V. Gorbunova; I. Irincheeva; Sibylle Jager; S. Jazwinski; M. Kaeberlein; B. Kennedy; D. Khaltourina; I. Kovalchuk; O. Kovalchuk; S. Kozin; A. Kulminski; E. Lashmanova; Ksenia V. Lezhnina; Guang-hui Liu; V. Longo; Polina Mamoshina; A. Maslov; João Pedro de Magalhães; James Mitchell; A. Mitnitski; Y. Nikolsky; I. Ozerov; E. Pasyukova; Darya Peregudova; V. Popov; E. Proshkina; E. Putin; E. Rogaev; B. Rogina; Jane Schastnaya; A. Seluanov; M. Shaposhnikov; A. Simm; V. Skulachev; M. Skulachev; I. Solovev; S. Spindler; N. Stefanova; Y. Suh; A. Swick; J. Tower; A. Gudkov; J. Vijg; A. Voronkov; Michael D. West; W. Wagner; A. Yashin; N. Zemskaya; Z. Zhumadilov; A. Zhavoronkov

Year: 2017

Venue: Aging

DOI: https://doi.org/10.18632/aging.101163

Paper Fasting for stem cell rejuvenation

Cristina González-Estévez; I. Flores · 2020 · Aging · DOI

Full title: Fasting for stem cell rejuvenation

Authors: Cristina González-Estévez; I. Flores

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.102912

Paper It is necessary to establish an International Agency for Research on Aging.

Anisimov, Vladimir N; Sidorenko, Alexandre V · 2018 · Aging · DOI

Full title: It is necessary to establish an International Agency for Research on Aging.

Authors: Anisimov, Vladimir N; Sidorenko, Alexandre V

Year: 2018

Venue: Aging

DOI: https://doi.org/10.18632/aging.101451

Paper Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.

Moskalev, Alexey; Chernyagina, Elizaveta; de Magalhães, João Pedro et al. · 2015 · Aging · DOI

Full title: Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.

Authors: Moskalev, Alexey; Chernyagina, Elizaveta; de Magalhães, João Pedro; Barardo, Diogo; Thoppil, Harikrishnan; Shaposhnikov, Mikhail; Budovsky, Arie; Fraifeld, Vadim E; Garazha, Andrew; Tsvetkov, Vasily; Bronovitsky, Evgeny; Bogomolov, Vladislav; Scerbacov, Alexei; Kuryan, Oleg; Gurinovich, Roman; Jellen, Leslie C; Kennedy, Brian; Mamoshina, Polina; Dobrovolskaya, Evgeniya; Aliper, Alex; Kaminsky, Dmitry; Zhavoronkov, Alex

Year: 2015

Venue: Aging

DOI: https://doi.org/10.18632/aging.100799

Paper Latest advances in aging research and drug discovery

Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano et al. · 2019 · Aging · DOI

Full title: Latest advances in aging research and drug discovery

Authors: Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano; Antebi, Adam; Barzilai, Nir; Bittner, Martin-Immanuel; Jensen, Martin Borch; Calkhoven, Cornelis F.; Chen, Danica; Grey, Aubrey D.N.J. de; Feige, Jérôme N.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Golato, Tyler; Gudkov, Andrei V.; Hoppe, Thorsten; Kaeberlein, Matt; Katajisto, Pekka; Kennedy, Brian K.; Lal, Unmesh; Martín-Villalba, Ana; Moskalev, Alexey; Ozerov, Ivan V.; Petr, Michael; Reason; Rubinsztein, David C.; Tyshkovskiy, Alexander; Vanhaelen, Quentin; Zhavoronkov, Alex; Scheibye‐Knudsen, Morten

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.102487

Paper Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 Drosophila species with different lifespans

M. Shaposhnikov; N. Zemskaya; Liubov A. Koval et al. · 2018 · Aging · DOI

Full title: Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 Drosophila species with different lifespans

Authors: M. Shaposhnikov; N. Zemskaya; Liubov A. Koval; E. V. Schegoleva; A. Zhavoronkov; A. Moskalev

Year: 2018

Venue: Aging

DOI: https://doi.org/10.18632/aging.101561

Paper Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori

Jiangbo Song; Guihua Jiang; Jianfei Zhang et al. · 2019 · Aging · DOI

Full title: Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori

Authors: Jiangbo Song; Guihua Jiang; Jianfei Zhang; Jie-Shu Guo; Zheng Li; Kaige Hao; Lian X Liu; Z. Cheng; X. Tong; F. Dai

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.101746

Paper Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?

Skulachev, Vladimir P; Shilovsky, Gregory A; Putyatina, Tatyana S et al. · 2020 · Aging · DOI

Full title: Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?

Authors: Skulachev, Vladimir P; Shilovsky, Gregory A; Putyatina, Tatyana S; Popov, Nikita A; Markov, Alexander V; Skulachev, Maxim V; Sadovnichii, Victor A

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.102981

Paper Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion.

Bartke, Andrzej; Evans, Tracy R; Musters, C J M · 2019 · Aging · DOI

Full title: Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion.

Authors: Bartke, Andrzej; Evans, Tracy R; Musters, C J M

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.102037

Paper A multi-tissue full lifespan epigenetic clock for mice.

Thompson, Michael J; Chwiałkowska, Karolina; Rubbi, Liudmilla et al. · 2018 · Aging · DOI

Full title: A multi-tissue full lifespan epigenetic clock for mice.

Authors: Thompson, Michael J; Chwiałkowska, Karolina; Rubbi, Liudmilla; Lusis, Aldons J; Davis, Richard C; Srivastava, Anuj; Korstanje, Ron; Churchill, Gary A; Horvath, Steve; Pellegrini, Matteo

Year: 2018

Venue: Aging

DOI: https://doi.org/10.18632/aging.101590

Paper From causes of aging to death from COVID-19.

Blagosklonny, Mikhail V · 2020 · Aging · DOI

Full title: From causes of aging to death from COVID-19.

Authors: Blagosklonny, Mikhail V

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.103493

Paper Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

Demidenko, Oleksandr; Barardo, Diogo; Budovskii, Valery et al. · 2021 · Aging · DOI

Full title: Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

Authors: Demidenko, Oleksandr; Barardo, Diogo; Budovskii, Valery; Finnemore, Robb; Palmer, Francis R.; Kennedy, Brian K.; Budovskaya, Yelena V.

Year: 2021

Venue: Aging

DOI: https://doi.org/10.18632/aging.203736

Paper Geroprotective effects of Alzheimer's disease drug candidates.

Kepchia, Devin; Currais, Antonio; Dargusch, Richard et al. · 2021 · Aging · DOI

Full title: Geroprotective effects of Alzheimer's disease drug candidates.

Authors: Kepchia, Devin; Currais, Antonio; Dargusch, Richard; Finley, Kim; Schubert, David; Maher, Pamela

Year: 2021

Venue: Aging

DOI: https://doi.org/10.18632/aging.202631

Paper When aging switches on Alzheimer’s

Yue Dong; Benjamin Harlan; G. Brewer · 2021 · Aging · DOI

Full title: When aging switches on Alzheimer’s

Authors: Yue Dong; Benjamin Harlan; G. Brewer

Year: 2021

Venue: Aging

DOI: https://doi.org/10.18632/aging.203085

Paper Meeting Report: Aging Research and Drug Discovery

Meron, Esther; Thaysen, Maria; Angeli, Suzanne et al. · 2022 · Aging · DOI

Full title: Meeting Report: Aging Research and Drug Discovery

Authors: Meron, Esther; Thaysen, Maria; Angeli, Suzanne; Antebi, Adam; Barzilai, Nir; Baur, Joseph A.; Bekker‐Jensen, Simon; Birkisdóttir, María B.; Bischof, Evelyne; Bruening, Jens; Brunet, Anne; Buchwalter, Abigail; Cabreiro, Filipe; Cai, Shi‐Qing; Chen, Brian H.; Ermolaeva, Maria; Ewald, Collin Y.; Ferrucci, Luigi; Florian, Maria Carolina; Fortney, Kristen; Freund, Adam; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David J.; Golato, Tyler; Gorbunova, Vera; Hoejimakers, Jan; Houtkooper, Riekelt H.; Jäger, Sibylle; Jaksch, Frank; Janssens, Georges E.; Jensen, Martin Borch; Kaeberlein, Matt; Karsenty, Gérard; Keizer, Peter L.J. de; Kennedy, Brian K.; Kirkland, James L.; Kjær, Michael; Kroemer, Guido; Lee, Kai-Fu; Lemaı̂tre, Jean-Marc; Liaskos, David; Longo, Valter D.; Lu, Yuxuan; MacArthur, Michael R.; Maier, Andrea B.; Manakanatas, Christina; Mitchell, Sarah J.; Moskalev, Alexey; Niedernhofer, Laura J.; Ozerov, Ivan V.; Partridge, Linda; Passegué, Emmanuelle; Petr, Michael; Peyer, James; Radenković, Dina; Rando, Thomas A.; Rattan, Suresh I. S.; Riedel, Christian G.; Rudolph, K. Lenhard; Ai, Ruixue; Serrano, Manuel; Schumacher, Björn; Sinclair, David; Smith, Ryan; Suh, Yousin; Taub, Pam R.; Trapp, Alexandre; Trendelenburg, Anne‐Ulrike; Valenzano, Dario Riccardo; Verburgh, Kris; Verdin, Eric; Vijg, Jan; Westendorp, Rudi G. J.; Zonari, Alessandra; Bakula, Daniela; Zhavoronkov, Alex; Scheibye‐Knudsen, Morten

Year: 2022

Venue: Aging

DOI: https://doi.org/10.18632/aging.203859

Paper Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.

Zhavoronkov, Alex · 2020 · Aging · DOI

Full title: Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.

Authors: Zhavoronkov, Alex

Year: 2020

Venue: Aging

DOI: https://doi.org/10.18632/aging.102988

Paper Predicting physiological aging rates from a range of quantitative traits using machine learning

Sun, Eric; Qian, Yong; Oppong, Richard et al. · 2021 · Aging · DOI

Full title: Predicting physiological aging rates from a range of quantitative traits using machine learning

Authors: Sun, Eric; Qian, Yong; Oppong, Richard; Bütler, Thomas; Zhao, Jesse; Chen, Brian H.; Tanaka, Toshiko; Kang, Jian; Sidore, Carlo; Cucca, Francesco; Bandinelli, Stefania; Abecasis, Gonçalo R.; Gorospe, Myriam; Ferrucci, Luigi; Schlessinger, David; Goldberg, I.; Ding, Jun

Year: 2021

Venue: Aging

DOI: https://doi.org/10.18632/aging.203660

Paper Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.

Al-Mansour, Fares; Alraddadi, Abdullah; He, Buwei et al. · 2023 · Aging · DOI

Full title: Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.

Authors: Al-Mansour, Fares; Alraddadi, Abdullah; He, Buwei; Saleh, Anes; Poblocka, Marta; Alzahrani, Wael; Cowley, Shaun; Macip, Salvador

Year: 2023

Venue: Aging

DOI: https://doi.org/10.18632/aging.204616

Paper Senolytic effect of high intensity interval exercise on human skeletal muscle.

Jean, Wei-Horng; Hsieh, Yu-Wen; Lai, Li-Fan et al. · 2023 · Aging · DOI

Full title: Senolytic effect of high intensity interval exercise on human skeletal muscle.

Authors: Jean, Wei-Horng; Hsieh, Yu-Wen; Lai, Li-Fan; Dewi, Luthfia; Liao, Yu-Chieh; Ye, Mengxin; Yu, Szu-Hsien; Kao, Chung-Lan; Huang, Chih-Yang; Kuo, Chia-Hua

Year: 2023

Venue: Aging

DOI: https://doi.org/10.18632/aging.204511

Paper Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

Barzilai, David · 2025 · Aging · DOI

Full title: Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

Authors: Barzilai, David

Year: 2025

Venue: Aging

DOI: https://doi.org/10.18632/aging.206189

Paper Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B. · 2024 · Aging · DOI

Full title: Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Authors: Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B.

Year: 2024

Venue: Aging

DOI: https://doi.org/10.18632/aging.205503

Paper Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

Blagosklonny, Mikhail V. · 2023 · Aging · DOI

Full title: Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

Authors: Blagosklonny, Mikhail V.

Year: 2023

Venue: Aging

DOI: https://doi.org/10.18632/aging.204920

Paper The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.

Banse, Stephen A; Jackson, E Grace; Sedore, Christine A et al. · 2024 · Aging · DOI

Full title: The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.

Authors: Banse, Stephen A; Jackson, E Grace; Sedore, Christine A; Onken, Brian; Hall, David; Coleman-Hulbert, Anna; Huynh, Phu; Garrett, Theo; Johnson, Erik; Harinath, Girish; Inman, Delaney; Guo, Suzhen; Morshead, Mackenzie; Xue, Jian; Falkowski, Ron; Chen, Esteban; Herrera, Christopher; Kirsch, Allie J; Perez, Viviana I; Guo, Max; Lithgow, Gordon J; Driscoll, Monica; Phillips, Patrick C

Year: 2024

Venue: Aging

DOI: https://doi.org/10.18632/aging.205743

Paper Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions.

Lee, Edwin; Carreras-Gallo, Natàlia; Lopez, Leilani et al. · 2024 · Aging · DOI

Full title: Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions.

Authors: Lee, Edwin; Carreras-Gallo, Natàlia; Lopez, Leilani; Turner, Logan; Lin, Aaron; Mendez, Tavis L; Went, Hannah; Tomusiak, Alan; Verdin, Eric; Corley, Michael; Ndhlovu, Lishomwa; Smith, Ryan; Dwaraka, Varun B

Year: 2024

Venue: Aging

DOI: https://doi.org/10.18632/aging.205581

Paper Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial.

Carreras-Gallo, Natalia; Dargham, Rita; Thorpe, Shealee P et al. · 2025 · Aging · DOI

Full title: Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial.

Authors: Carreras-Gallo, Natalia; Dargham, Rita; Thorpe, Shealee P; Warren, Steve; Mendez, Tavis L; Smith, Ryan; Macpherson, Greg; Dwaraka, Varun B

Year: 2025

Venue: Aging

DOI: https://doi.org/10.18632/aging.206221

Paper Role of growth differentiation factor 11 in development, physiology and disease

Zhang, Yonghui; Wei, Yong; Liu, Dan et al. · 2017 · Oncotarget · DOI

Full title: Role of growth differentiation factor 11 in development, physiology and disease

Authors: Zhang, Yonghui; Wei, Yong; Liu, Dan; Liu, Feng; Li, Xiaoshan; Pan, Lianhong; Pang, Yi; Chen, Dilong

Year: 2017

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.20258

Paper Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors.

Mohammad, Karamat; Titorenko, Vladimir I · 2021 · Oncotarget · DOI

Full title: Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors.

Authors: Mohammad, Karamat; Titorenko, Vladimir I

Year: 2021

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.27926

Paper Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Sousa‐Victor, Pedro; García‐Prat, Laura; Muñoz‐Cánoves, Pura · 2015 · Oncotarget · DOI

Full title: Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Authors: Sousa‐Victor, Pedro; García‐Prat, Laura; Muñoz‐Cánoves, Pura

Year: 2015

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.5563

Paper Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast.

Mohammad, Karamat; Orfanos, Emmanuel; Titorenko, Vladimir I · 2021 · Oncotarget · DOI

Full title: Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast.

Authors: Mohammad, Karamat; Orfanos, Emmanuel; Titorenko, Vladimir I

Year: 2021

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.28133

Paper Epigenetic dysregulation in cardiovascular aging and disease.

Herman, Allison B; Occean, James R; Sen, Payel · 2021 · The journal of cardiovascular aging · DOI

Full title: Epigenetic dysregulation in cardiovascular aging and disease.

Authors: Herman, Allison B; Occean, James R; Sen, Payel

Year: 2021

Venue: The journal of cardiovascular aging

DOI: https://doi.org/10.20517/jca.2021.16

Paper Gut microbiota: an ideal biomarker and intervention strategy for aging.

Xu, Xuan; Xu, Tangchang; Wei, Jing et al. · 2024 · Microbiome research reports · DOI

Full title: Gut microbiota: an ideal biomarker and intervention strategy for aging.

Authors: Xu, Xuan; Xu, Tangchang; Wei, Jing; Chen, Tingtao

Year: 2024

Venue: Microbiome research reports

DOI: https://doi.org/10.20517/mrr.2023.68

Paper Does Modulation of an Epigenetic Clock Define a Geroprotector?

Schork, Nicholas J; Beaulieu-Jones, Brett; Liang, Winnie et al. · 2022 · Advances in geriatric medicine and research · DOI

Full title: Does Modulation of an Epigenetic Clock Define a Geroprotector?

Authors: Schork, Nicholas J; Beaulieu-Jones, Brett; Liang, Winnie; Smalley, Susan; Goetz, Laura H

Year: 2022

Venue: Advances in geriatric medicine and research

DOI: https://doi.org/10.20900/agmr20220002

Paper Modulation of Endocannabinoids by Caloric Restriction is Conserved in Mice but is not Required for the Protection from Acute Kidney Injury

Hoyer-Allo, Karla Johanna Ruth; Späth, Martin R.; Hanßen, Ruth et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Modulation of Endocannabinoids by Caloric Restriction is Conserved in Mice but is not Required for the Protection from Acute Kidney Injury

Authors: Hoyer-Allo, Karla Johanna Ruth; Späth, Martin R.; Hanßen, Ruth; Johnsen, Marc; Brodesser, Susanne; Kaufmann, Kathrin; Kiefer, Katharina; Koehler, Felix C.; Göbel, Heike; Kubacki, Torsten; Grundmann, Franziska; Schermer, Bernhard; Brüning, Jens C.; Benzing, Thomas; Burst, Volker; Müller, Roman‐Ulrich

Year: 2021

Venue: International Journal of Molecular Sciences

Paper Editorial: DNA repair and interventions in aging

Brosh, Robert M.; Moskalev, Alexey; Gorbunova, Vera · 2023 · Frontiers in Aging · DOI

Full title: Editorial: DNA repair and interventions in aging

Authors: Brosh, Robert M.; Moskalev, Alexey; Gorbunova, Vera

Year: 2023

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2023.1306463

Paper Exploring juventology: unlocking the secrets of youthspan and longevity programs

Brandhorst, Sebastian; Longo, Valter D. · 2024 · Frontiers in Aging · DOI

Full title: Exploring juventology: unlocking the secrets of youthspan and longevity programs

Authors: Brandhorst, Sebastian; Longo, Valter D.

Year: 2024

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2024.1379289

Paper Sirolimus use in allogeneic hematopoietic cell transplant recipients: assessing its senotherapeutic role in a high risk population

Najla El Jurdi; Heba Elhusseini; Qing Cao et al. · 2025 · Frontiers in Aging · DOI

Full title: Sirolimus use in allogeneic hematopoietic cell transplant recipients: assessing its senotherapeutic role in a high risk population

Authors: Najla El Jurdi; Heba Elhusseini; Qing Cao; Thomas Klinger; Ella Shapiro; Melike Cömert; M. Juckett; S. Holtan; Matthew J. Yousefzadeh

Year: 2025

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2025.1673230

Paper Geroscience and pathology: a new frontier in understanding age-related diseases.

Fekete, Monika; Major, David; Feher, Agnes et al. · 2024 · Pathology oncology research : POR · DOI

Full title: Geroscience and pathology: a new frontier in understanding age-related diseases.

Authors: Fekete, Monika; Major, David; Feher, Agnes; Fazekas-Pongor, Vince; Lehoczki, Andrea

Year: 2024

Venue: Pathology oncology research : POR

DOI: https://doi.org/10.3389/pore.2024.1611623

Paper Therapeutic Antiaging Strategies

Mishra, Shailendra Kumar; Balendra, Vyshnavy; Esposto, Josephine et al. · 2022 · Biomedicines · DOI

Full title: Therapeutic Antiaging Strategies

Authors: Mishra, Shailendra Kumar; Balendra, Vyshnavy; Esposto, Josephine; Obaid, Ahmad A.; Maccioni, Ricardo B.; Jha, Niraj Kumar; Perry, George; Moustafa, Mahmoud; Al-Shehri, Mohammed; Singh, Mahendra Pratap; Khan, Anmar A.; Vamanu, Emanuel; Singh, Sandeep Kumar

Year: 2022

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines10102515

Paper Influence of Adipokines on Metabolic Dysfunction and Aging.

Park, Seongjoon; Shimokawa, Isao · 2024 · Biomedicines · DOI

Full title: Influence of Adipokines on Metabolic Dysfunction and Aging.

Authors: Park, Seongjoon; Shimokawa, Isao

Year: 2024

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines12040873

Paper New Trends in Aging Drug Discovery

B. Benhamú; M. Martín-Fontecha; Henar Vázquez-Villa et al. · 2022 · Biomedicines · DOI

Full title: New Trends in Aging Drug Discovery

Authors: B. Benhamú; M. Martín-Fontecha; Henar Vázquez-Villa; M. López-Rodríguez; S. Ortega‐Gutiérrez

Year: 2022

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines10082006

Paper Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging

Yu, Mengdi; Zhang, Hongxia; Wang, Brian et al. · 2021 · Cells · DOI

Full title: Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging

Authors: Yu, Mengdi; Zhang, Hongxia; Wang, Brian; Zhang, Yinuo; Zheng, Xiaoying; Shao, Bei; Zhuge, Qichuan; Jin, Kunlin

Year: 2021

Venue: Cells

DOI: https://doi.org/10.3390/cells10030660

Paper Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

Statsenko, Yauhen; Kuznetsov, Nikolai V.; Morozova, Daria et al. · 2023 · Cells · DOI

Full title: Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

Authors: Statsenko, Yauhen; Kuznetsov, Nikolai V.; Morozova, Daria; Liaonchyk, Katsiaryna; Simiyu, Gillian; Smetanina, Darya; Kashapov, Aidar; Meribout, Sarah; Gorkom, Klaus; Hamoudi, Rifat; Ismail, Fatima; Ansari, Suraiya Anjum; Emerald, Bright Starling; Ljubisavljević, Miloš

Year: 2023

Venue: Cells

Paper Senescent Cells: Dual Implications on the Retinal Vascular System

Mohammad Reza Habibi-Kavashkohie; T. Scorza; Malika Oubaha · 2023 · Cells · DOI

Full title: Senescent Cells: Dual Implications on the Retinal Vascular System

Authors: Mohammad Reza Habibi-Kavashkohie; T. Scorza; Malika Oubaha

Year: 2023

Venue: Cells

DOI: https://doi.org/10.3390/cells12192341

Paper Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice

McGill, Cassandra; Christensen, Amy; Qian, Wenjie et al. · 2024 · DOI

Full title: Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice

Authors: McGill, Cassandra; Christensen, Amy; Qian, Wenjie; Thorwald, Max A.; Lugo, Jose Godoy; Namvari, Sara; White, Olivia S.; Finch, Caleb E.; Benayoun, Bérénice A.; Pike, Christian J.

Year: 2024

DOI: https://doi.org/10.1101/2024.03.12.584678

Paper Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Guelfi, Gabriella; Capaccia, Camilla; Tedeschi, Martina et al. · 2024 · Cells · DOI

Full title: Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Authors: Guelfi, Gabriella; Capaccia, Camilla; Tedeschi, Martina; Bufalari, Antonello; Leonardi, Leonardo; Cenci‐Goga, Beniamino T.; Maranesi, Margherita

Year: 2024

Venue: Cells

DOI: https://doi.org/10.3390/cells13242101

Paper Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones.

Bramwell, Laura R; Frankum, Ryan; Harries, Lorna W · 2024 · Cells · DOI

Full title: Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones.

Authors: Bramwell, Laura R; Frankum, Ryan; Harries, Lorna W

Year: 2024

Venue: Cells

DOI: https://doi.org/10.3390/cells13060517

Paper Assessment of Pullulan, a Microbial Polysaccharide, as a Matrix for Senotherapeutics Delivery

Ramona-Daniela Păvăloiu; Fawzia Sha’at; Corina Bubueanu et al. · 2023 · Priochem 2023 · DOI

Full title: Assessment of Pullulan, a Microbial Polysaccharide, as a Matrix for Senotherapeutics Delivery

Authors: Ramona-Daniela Păvăloiu; Fawzia Sha’at; Corina Bubueanu; M. Petrescu; Claudia Sevcenco

Year: 2023

Venue: Priochem 2023

DOI: https://doi.org/10.3390/chemproc2023013023

Paper Molecular Regulation of SASP in Cellular Senescence: Therapeutic Implications and Translational Challenges.

Klepacki, Hubert; Kowalczuk, Krystyna; Łepkowska, Natalia et al. · 2025 · Cells · DOI

Full title: Molecular Regulation of SASP in Cellular Senescence: Therapeutic Implications and Translational Challenges.

Authors: Klepacki, Hubert; Kowalczuk, Krystyna; Łepkowska, Natalia; Hermanowicz, Justyna Magdalena

Year: 2025

Venue: Cells

DOI: https://doi.org/10.3390/cells14130942

Paper Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions

Yan, Bowen; Yuan, Qingchen; Guryanova, Olga A. · 2023 · Epigenomes · DOI

Full title: Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions

Authors: Yan, Bowen; Yuan, Qingchen; Guryanova, Olga A.

Year: 2023

Venue: Epigenomes

DOI: https://doi.org/10.3390/epigenomes7040032

Paper The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Bjedov, Ivana; Rallis, Charalampos · 2020 · Genes · DOI

Full title: The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Authors: Bjedov, Ivana; Rallis, Charalampos

Year: 2020

Venue: Genes

DOI: https://doi.org/10.3390/genes11091043

Paper The Role of Ghrelin and Ghrelin Signaling in Aging

Amitani, Marie; Amitani, Haruka; Cheng, Kai‐Chun et al. · 2017 · International Journal of Molecular Sciences · DOI

Full title: The Role of Ghrelin and Ghrelin Signaling in Aging

Authors: Amitani, Marie; Amitani, Haruka; Cheng, Kai‐Chun; Kairupan, Timothy Sean; Sameshima, Nanami; Shimoshikiryo, Ippei; Mizuma, Kimiko; Rokot, Natasya Trivena; Nerome, Yasuhito; Owaki, Tetsuhiro; Asakawa, Akihiro; Inui, Akio

Year: 2017

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms18071511

Paper Longevity: Lesson from Model Organisms.

Taormina, Giusi; Ferrante, Federica; Vieni, Salvatore et al. · 2019 · Genes · DOI

Full title: Longevity: Lesson from Model Organisms.

Authors: Taormina, Giusi; Ferrante, Federica; Vieni, Salvatore; Grassi, Nello; Russo, Antonio; Mirisola, Mario G

Year: 2019

Venue: Genes

DOI: https://doi.org/10.3390/genes10070518

Paper Treating Senescence like Cancer: Novel Perspectives in Senotherapy of Chronic Diseases.

Mongelli, Alessia; Atlante, Sandra; Barbi, Veronica et al. · 2020 · International journal of molecular sciences · DOI

Full title: Treating Senescence like Cancer: Novel Perspectives in Senotherapy of Chronic Diseases.

Authors: Mongelli, Alessia; Atlante, Sandra; Barbi, Veronica; Bachetti, Tiziana; Martelli, Fabio; Farsetti, Antonella; Gaetano, Carlo

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21217984

Paper Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury

Hoyer-Allo, Karla Johanna Ruth; Späth, Martin R.; Hanßen, Ruth et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.12688/f1000research.12120.1

Paper Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue

Kobayashi, Masaki; Deguchi, Yusuke; Nozaki, Yuka et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue

Authors: Kobayashi, Masaki; Deguchi, Yusuke; Nozaki, Yuka; Higami, Yoshikazu

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms22116025

Paper The Impact of Caloric Restriction on the Epigenetic Signatures of Aging

Noémie Gensous; C. Franceschi; A. Santoro et al. · 2019 · International Journal of Molecular Sciences · DOI

Full title: The Impact of Caloric Restriction on the Epigenetic Signatures of Aging

Authors: Noémie Gensous; C. Franceschi; A. Santoro; M. Milazzo; P. Garagnani; M. Bacalini

Year: 2019

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms20082022

Paper Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

M. Jové; R. Cabré; N. Mota-Martorell et al. · 2021 · International Journal of Molecular Sciences · DOI

Full title: Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

Authors: M. Jové; R. Cabré; N. Mota-Martorell; Meritxell Martín-Garí; È. Òbis; Paula Ramos; Iván Canales; José Daniel Galo-Licona; J. Sol; L. Nogueras; P. Torres; M. Portero-Otín; V. Ayala; I. Ferrer; R. Pamplona

Year: 2021

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms222212517

Paper Mitochondrial Aging and Senolytic Natural Products with Protective Potential.

Deledda, Andrea; Giordano, Emanuele; Velluzzi, Fernanda et al. · 2022 · International journal of molecular sciences · DOI

Full title: Mitochondrial Aging and Senolytic Natural Products with Protective Potential.

Authors: Deledda, Andrea; Giordano, Emanuele; Velluzzi, Fernanda; Flore, Giovanna; Franceschelli, Sara; Speranza, Lorenza; Ripari, Patrizio

Year: 2022

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms232416219

Paper Cellular senescence: a key therapeutic target in aging and diseases.

Zhang, Lei; Pitcher, Louise E; Yousefzadeh, Matthew J et al. · 2022 · The Journal of clinical investigation · DOI

Full title: Cellular senescence: a key therapeutic target in aging and diseases.

Authors: Zhang, Lei; Pitcher, Louise E; Yousefzadeh, Matthew J; Niedernhofer, Laura J; Robbins, Paul D; Zhu, Yi

Year: 2022

Venue: The Journal of clinical investigation

DOI: https://doi.org/10.1172/JCI158450

Paper Rapamycin extends murine lifespan but has limited effects on aging

Neff, Frauke; Flores-Dominguez, Diana; Ryan, Devon et al. · 2013 · Journal of Clinical Investigation · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging

Authors: Neff, Frauke; Flores-Dominguez, Diana; Ryan, Devon; Horsch, Marion; Schröder, Susanne; Adler, Thure; Afonso, Luciana Caminha; Aguilar‐Pimentel, Juan Antonio; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hettich, Moritz M.; Holtmeier, Richard; Hölter, Sabine M.; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Rácz, Ildikó; Rathkolb, Birgit; Rozman, Jan; Naton, Beatrix; Ordemann, Rainer; Adamski, Jerzy; Beckers, Johannes; Bekeredjian, Raffi; Busch, Dirk H.; Ehninger, Gerhard; Graw, Jochen; Höfler, Heinz; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Stypmann, Jörg; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Fuchs, Helmut; Gailus‐Durner, Valérie; Angelis, Martin Hrabě de; Ehninger, Dan

Year: 2013

Venue: Journal of Clinical Investigation

DOI: https://doi.org/10.1172/jci67674

Paper Diminished mTOR signaling: a common mode of action for endocrine longevity factors

Lamming, Dudley W. · 2014 · SpringerPlus · DOI

Full title: Diminished mTOR signaling: a common mode of action for endocrine longevity factors

Authors: Lamming, Dudley W.

Year: 2014

Venue: SpringerPlus

DOI: https://doi.org/10.1186/2193-1801-3-735

Paper Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.

Sutphin, George L; Bishop, Emma; Yanos, Melana E et al. · 2012 · Longevity & healthspan · DOI

Full title: Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.

Authors: Sutphin, George L; Bishop, Emma; Yanos, Melana E; Moller, Richard M; Kaeberlein, Matt

Year: 2012

Venue: Longevity & healthspan

DOI: https://doi.org/10.1186/2046-2395-1-9

Paper Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender

Xu, X.Z. Shawn; Zhan, Ming; Duan, Wenzhen et al. · 2007 · Genome biology · DOI

Full title: Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender

Authors: Xu, X.Z. Shawn; Zhan, Ming; Duan, Wenzhen; Prabhu, Vinayakumar; Brenneman, Randall; Wood, William H.; Firman, Jeff; Li, Huai; Zhang, Peisu; Ibe, Carol N.; Zonderman, Alan B.; Longo, Dan L.; Poosala, Suresh; Becker, Kevin G.; Mattson, Mark P.

Year: 2007

Venue: Genome biology

DOI: https://doi.org/10.1186/gb-2007-8-11-r234

Paper Geroprotector drugs and exercise: friends or foes on healthy longevity?

Elliehausen, Christian J; Anderson, Rozalyn M; Diffee, Gary M et al. · 2023 · BMC biology · DOI

Full title: Geroprotector drugs and exercise: friends or foes on healthy longevity?

Authors: Elliehausen, Christian J; Anderson, Rozalyn M; Diffee, Gary M; Rhoads, Timothy W; Lamming, Dudley W; Hornberger, Troy A; Konopka, Adam R

Year: 2023

Venue: BMC biology

DOI: https://doi.org/10.1186/s12915-023-01779-9

Paper Fifteen years of progress in understanding frailty and health in aging

Rockwood, Kenneth; Howlett, Susan E. · 2018 · BMC Medicine · DOI

Full title: Fifteen years of progress in understanding frailty and health in aging

Authors: Rockwood, Kenneth; Howlett, Susan E.

Year: 2018

Venue: BMC Medicine

DOI: https://doi.org/10.1186/s12916-018-1223-3

Paper Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin.

Raffaele, Marco; Kovacovicova, Kristina; Frohlich, Jan et al. · 2021 · Cell communication and signaling : CCS · DOI

Full title: Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin.

Authors: Raffaele, Marco; Kovacovicova, Kristina; Frohlich, Jan; Lo Re, Oriana; Giallongo, Sebastiano; Oben, Jude A; Faldyna, Martin; Leva, Lenka; Giannone, Antonino Giulio; Cabibi, Daniela; Vinciguerra, Manlio

Year: 2021

Venue: Cell communication and signaling : CCS

DOI: https://doi.org/10.1186/s12964-021-00731-0

Paper The impacts of different dietary restriction regimens on aging and longevity: from yeast to humans.

Ching, Tsui-Ting; Hsu, Ao-Lin · 2025 · Journal of biomedical science · DOI

Full title: The impacts of different dietary restriction regimens on aging and longevity: from yeast to humans.

Authors: Ching, Tsui-Ting; Hsu, Ao-Lin

Year: 2025

Venue: Journal of biomedical science

DOI: https://doi.org/10.1186/s12929-025-01188-w

Paper Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives

A. Vaiserman; O. Lushchak · 2017 · Journal of Translational Medicine · DOI

Full title: Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives

Authors: A. Vaiserman; O. Lushchak

Year: 2017

Venue: Journal of Translational Medicine

DOI: https://doi.org/10.1186/s12967-017-1259-8

Paper The sex- and duration-dependent effects of intermittent fasting on lifespan and reproduction of spider mite Tetranychus urticae

Li, Guangyun; Zhang, Zhi‐Qiang · 2019 · Frontiers in Zoology · DOI

Full title: The sex- and duration-dependent effects of intermittent fasting on lifespan and reproduction of spider mite Tetranychus urticae

Authors: Li, Guangyun; Zhang, Zhi‐Qiang

Year: 2019

Venue: Frontiers in Zoology

DOI: https://doi.org/10.1186/s12983-019-0310-4

Paper The influence of the geroprotective cytokine on the transcriptome of young and senescent mesenchymal stem cells.

Kondratyeva, Liya G; Matveeva, Diana K; Ezdakova, Maria I et al. · 2025 · BMC research notes · DOI

Full title: The influence of the geroprotective cytokine on the transcriptome of young and senescent mesenchymal stem cells.

Authors: Kondratyeva, Liya G; Matveeva, Diana K; Ezdakova, Maria I; Utkina, Marina V; Ratushnyy, Andrey Yu

Year: 2025

Venue: BMC research notes

DOI: https://doi.org/10.1186/s13104-025-07262-8

Paper PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan.

Alfatah, Mohammad; Zhang, Yizhong; Naaz, Arshia et al. · 2024 · Biology direct · DOI

Full title: PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan.

Authors: Alfatah, Mohammad; Zhang, Yizhong; Naaz, Arshia; Cheng, Trishia Yi Ning; Eisenhaber, Frank

Year: 2024

Venue: Biology direct

DOI: https://doi.org/10.1186/s13062-024-00455-4

Paper The aging mouse microbiome has obesogenic characteristics

Binyamin, Dana; Werbner, Nir; Nuriel‐Ohayon, Meital et al. · 2020 · Genome Medicine · DOI

Full title: The aging mouse microbiome has obesogenic characteristics

Authors: Binyamin, Dana; Werbner, Nir; Nuriel‐Ohayon, Meital; Uzan, Atara; Mor, Hadar; Abbas, Atallah; Oren, Ziv; Teperino, Raffaele; Gutman, Roee; Koren, Omry

Year: 2020

Venue: Genome Medicine

DOI: https://doi.org/10.1186/s13073-020-00784-9

Paper Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

Tajuddin, Salman M.; Hernández, Dena; Chen, Brian H. et al. · 2019 · Clinical Epigenetics · DOI

Full title: Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

Authors: Tajuddin, Salman M.; Hernández, Dena; Chen, Brian H.; Hooten, Nicole Noren; Mode, Nicolle A.; Nalls, Mike A.; Singleton, Andrew B.; Ejiogu, Ngozi; Chitrala, Kumaraswamy Naidu; Zonderman, Alan B.; Evans, Michele K.

Year: 2019

Venue: Clinical Epigenetics

DOI: https://doi.org/10.1186/s13148-019-0722-1

Paper Structure-based machine learning screening identifies natural product candidates as potential geroprotectors.

Santiago-de-la-Cruz, Jose Alberto; Rivero-Segura, Nadia Alejandra; Gomez-Verjan, Juan Carlos · 2025 · Journal of cheminformatics · DOI

Full title: Structure-based machine learning screening identifies natural product candidates as potential geroprotectors.

Authors: Santiago-de-la-Cruz, Jose Alberto; Rivero-Segura, Nadia Alejandra; Gomez-Verjan, Juan Carlos

Year: 2025

Venue: Journal of cheminformatics

DOI: https://doi.org/10.1186/s13321-025-01058-5

Paper Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging

M. Boroni; Alessandra Zonari; Carolina Reis de Oliveira et al. · 2020 · Clinical Epigenetics · DOI

Full title: Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging

Authors: M. Boroni; Alessandra Zonari; Carolina Reis de Oliveira; Kallie Alkatib; E. A. Ochoa Cruz; L. Brace; Juliana Lott de Carvalho

Year: 2020

Venue: Clinical Epigenetics

DOI: https://doi.org/10.1186/s13148-020-00899-1

Paper Akkermansia muciniphila, which is enriched in the gut microbiota by metformin, improves cognitive function in aged mice by reducing the proinflammatory cytokine interleukin-6

Zhu, Xiaoqi; Shen, Junyan; Feng, Shengyu et al. · 2023 · Microbiome · DOI

Full title: Akkermansia muciniphila, which is enriched in the gut microbiota by metformin, improves cognitive function in aged mice by reducing the proinflammatory cytokine interleukin-6

Authors: Zhu, Xiaoqi; Shen, Junyan; Feng, Shengyu; Huang, Ce; Wang, Hao; Huo, Fengjiao; Liu, Hailiang

Year: 2023

Venue: Microbiome

DOI: https://doi.org/10.1186/s40168-023-01567-1

Paper Attenuation of primate aging via systemic infusion of senescence-resistant mesenchymal progenitor cells.

Siddique, Aisha; Shakir, Ismail M; Li, Mo · 2025 · Cell regeneration (London, England) · DOI

Full title: Attenuation of primate aging via systemic infusion of senescence-resistant mesenchymal progenitor cells.

Authors: Siddique, Aisha; Shakir, Ismail M; Li, Mo

Year: 2025

Venue: Cell regeneration (London, England)

DOI: https://doi.org/10.1186/s13619-025-00248-8

Paper [Analysis of aging-related oxidative stress status in normal aging animals and development of anti-aging interventions].

Sasaki, Toru · 2010 · Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan · DOI

Full title: [Analysis of aging-related oxidative stress status in normal aging animals and development of anti-aging interventions].

Authors: Sasaki, Toru

Year: 2010

Venue: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

DOI: https://doi.org/10.1248/yakushi.130.29

Paper NAD + biosynthesis, aging, and disease

Sean Johnson; S. Imai · 2018 · F1000Research · DOI

Full title: NAD + biosynthesis, aging, and disease

Authors: Sean Johnson; S. Imai

Year: 2018

Venue: F1000Research

Paper Geroscience approaches to increase healthspan and slow aging

Melov, Simon · 2016 · F1000Research · DOI

Full title: Geroscience approaches to increase healthspan and slow aging

Authors: Melov, Simon

Year: 2016

Venue: F1000Research

DOI: https://doi.org/10.12688/f1000research.7583.1

Paper Dietary restriction with and without caloric restriction for healthy aging

Lee, Changhan; Longo, Valter D. · 2016 · F1000Research · DOI

Full title: Dietary restriction with and without caloric restriction for healthy aging

Authors: Lee, Changhan; Longo, Valter D.

Year: 2016

Venue: F1000Research

DOI: https://doi.org/10.12688/f1000research.7136.1

Paper Energy restriction and potential energy restriction mimetics

Nikolai, Sibylle; Pallauf, Kathrin; Huebbe, Patricia et al. · 2015 · Nutrition Research Reviews · DOI

Full title: Energy restriction and potential energy restriction mimetics

Authors: Nikolai, Sibylle; Pallauf, Kathrin; Huebbe, Patricia; Rimbach, Gerald

Year: 2015

Venue: Nutrition Research Reviews

DOI: https://doi.org/10.1017/s0954422415000062

Paper Gene expression signatures of human cell and tissue longevity.

Seim, Inge; Ma, Siming; Gladyshev, Vadim N · 2016 · NPJ aging and mechanisms of disease · DOI

Full title: Gene expression signatures of human cell and tissue longevity.

Authors: Seim, Inge; Ma, Siming; Gladyshev, Vadim N

Year: 2016

Venue: NPJ aging and mechanisms of disease

DOI: https://doi.org/10.1038/npjamd.2016.14

Paper Defining molecular basis for longevity traits in natural yeast isolates

Kaya, Alaattin; Ma, Siming; Wasko, Brian M. et al. · 2015 · npj Aging and Mechanisms of Disease · DOI

Full title: Defining molecular basis for longevity traits in natural yeast isolates

Authors: Kaya, Alaattin; Ma, Siming; Wasko, Brian M.; Lee, Mitchell; Kaeberlein, Matt; Gladyshev, Vadim N.

Year: 2015

Venue: npj Aging and Mechanisms of Disease

DOI: https://doi.org/10.1038/npjamd.2015.1

Paper Systemic regulation of mammalian ageing and longevity by brain sirtuins

Satoh, Akiko; Imai, Shin‐ichiro · 2014 · Nature Communications · DOI

Full title: Systemic regulation of mammalian ageing and longevity by brain sirtuins

Authors: Satoh, Akiko; Imai, Shin‐ichiro

Year: 2014

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms5211

Paper Defining regorafenib as a senomorphic drug: therapeutic potential in the age-related lung disease emphysema.

Park, Jung-Jin; Oh, Kwangseok; Lee, Gun-Wu et al. · 2023 · Experimental & molecular medicine · DOI

Full title: Defining regorafenib as a senomorphic drug: therapeutic potential in the age-related lung disease emphysema.

Authors: Park, Jung-Jin; Oh, Kwangseok; Lee, Gun-Wu; Bang, Geul; Park, Jin-Hee; Kim, Han-Byeol; Kim, Jin Young; Shin, Eun-Young; Kim, Eung-Gook

Year: 2023

Venue: Experimental & molecular medicine

DOI: https://doi.org/10.1038/s12276-023-00966-6

Paper Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics.

Han, Yeaeun; Kim, Sung Young · 2023 · Experimental & molecular medicine · DOI

Full title: Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics.

Authors: Han, Yeaeun; Kim, Sung Young

Year: 2023

Venue: Experimental & molecular medicine

DOI: https://doi.org/10.1038/s12276-022-00906-w

Paper The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

S. Imai · 2016 · npj Systems Biology and Applications · DOI

Full title: The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

Authors: S. Imai

Year: 2016

Venue: npj Systems Biology and Applications

DOI: https://doi.org/10.1038/npjsba.2016.18

Paper Targeting the “hallmarks of aging” to slow aging and treat age-related disease: fact or fiction?

Keshavarz, Maryam; Xie, Kan; Schaaf, Kristina et al. · 2022 · Molecular Psychiatry · DOI

Full title: Targeting the “hallmarks of aging” to slow aging and treat age-related disease: fact or fiction?

Authors: Keshavarz, Maryam; Xie, Kan; Schaaf, Kristina; Bano, Daniele; Ehninger, Dan

Year: 2022

Venue: Molecular Psychiatry

DOI: https://doi.org/10.1038/s41380-022-01680-x

Paper Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Lucanic, Mark; Plummer, W. Todd; Chen, Esteban et al. · 2017 · Nature Communications · DOI

Full title: Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Authors: Lucanic, Mark; Plummer, W. Todd; Chen, Esteban; Harke, Jailynn; Foulger, Anna; Onken, Brian; Coleman-Hulbert, Anna L; Dumas, Kathleen J.; Guo, Suzhen; Johnson, Erik; Bhaumik, Dipa; Xue, Jian; Crist, Anna; Presley, Michael P.; Harinath, Girish; Sedore, Christine A.; Chamoli, Manish; Kamat, Shaunak; Chen, Michelle K.; Angeli, Suzanne; Chang, Christina; Willis, John H.; Edgar, Daniel; Royal, Mary Anne; Chao, Elizabeth A.; Patel, Shobhna; Garrett, Theo; Ibáñez‐Ventoso, Carolina; Hope, June; Kish, Jason L.; Guo, Max; Lithgow, Gordon J.; Driscoll, Monica; Phillips, Patrick C.

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/ncomms14256

Paper Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline

E. Ciaglia; V. Lopardo; F. Montella et al. · 2022 · Cell Death and Disease · DOI

Full title: Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline

Authors: E. Ciaglia; V. Lopardo; F. Montella; Albino Carrizzo; P. Di Pietro; M. Malavolta; R. Giacconi; F. Orlando; M. Cattaneo; P. Madeddu; C. Vecchione; A. Puca

Year: 2022

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-022-04535-z

Paper Immunosenescence: molecular mechanisms and diseases

Liu, Zaoqu; Liang, Qimeng; Ren, Yuqing et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Immunosenescence: molecular mechanisms and diseases

Authors: Liu, Zaoqu; Liang, Qimeng; Ren, Yuqing; Guo, Chunguang; Ge, Xiaoyong; Wang, Libo; Cheng, Quan; Luo, Peng; Zhang, Yi; Han, Xinwei

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01451-2

Paper Nintedanib induces senolytic effect via STAT3 inhibition.

Cho, Hyun-Ji; Hwang, Jeong-A; Yang, Eun Jae et al. · 2022 · Cell death & disease · DOI

Full title: Nintedanib induces senolytic effect via STAT3 inhibition.

Authors: Cho, Hyun-Ji; Hwang, Jeong-A; Yang, Eun Jae; Kim, Eok-Cheon; Kim, Jae-Ryong; Kim, Sung Young; Kim, Young Zoon; Park, Sang Chul; Lee, Young-Sam

Year: 2022

Venue: Cell death & disease

DOI: https://doi.org/10.1038/s41419-022-05207-8

Paper Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy

Wu, Qi; Tian, Ai-Ling; Durand, Sylvère et al. · 2020 · Cell Death and Disease · DOI

Full title: Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy

Authors: Wu, Qi; Tian, Ai-Ling; Durand, Sylvère; Aprahamian, Fanny; Nirmalathasan, Nitharsshini; Xie, Wei; Liu, Peng; Zhao, Liwei; Zhang, Shuai; Pan, Hui; Carmona‐Gutiérrez, Didac; Madeo, Frank; Tu, Yi; Kepp, Oliver; Kroemer, Guido

Year: 2020

Venue: Cell Death and Disease

DOI: https://doi.org/10.1038/s41419-020-03226-x

Paper Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice.

Cai, Yusheng; Zhou, Huanhuan; Zhu, Yinhua et al. · 2020 · Cell research · DOI

Full title: Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice.

Authors: Cai, Yusheng; Zhou, Huanhuan; Zhu, Yinhua; Sun, Qi; Ji, Yin; Xue, Anqi; Wang, Yuting; Chen, Wenhan; Yu, Xiaojie; Wang, Longteng; Chen, Han; Li, Cheng; Luo, Tuoping; Deng, Hongkui

Year: 2020

Venue: Cell research

DOI: https://doi.org/10.1038/s41422-020-0314-9

Paper A β-galactosidase kiss of death for senescent cells

Xiaoqian Liu; J. Belmonte; Weiqi Zhang et al. · 2020 · Cell Research · DOI

Full title: A β-galactosidase kiss of death for senescent cells

Authors: Xiaoqian Liu; J. Belmonte; Weiqi Zhang; Guang-Hui Liu

Year: 2020

Venue: Cell Research

DOI: https://doi.org/10.1038/s41422-020-0325-6

Paper Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

Xie, Kan; Neff, Frauke; Markert, Astrid et al. · 2017 · Nature Communications · DOI

Full title: Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

Authors: Xie, Kan; Neff, Frauke; Markert, Astrid; Rozman, Jan; Aguilar‐Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Brommage, Robert; Garrett, Lillian; Henzel, Kristin S.; Hölter, Sabine M.; Janik, Dirk; Lehmann, Isabelle; Moreth, Kristin; Pearson, Brandon L.; Rácz, Ildikó; Rathkolb, Birgit; Ryan, Devon; Schröder, Susanne; Treise, Irina; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Ehninger, Gerhard; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Sandholzer, Michael A.; Schmidt‐Weber, Carsten B.; Weiergräber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Gailus‐Durner, Valérie; Fuchs, Helmut; Angelis, Martin Hrabě de; Ehninger, Dan

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-017-00178-3

Paper Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

Martens, Christopher R.; Denman, Blair A.; Mazzo, Melissa R. et al. · 2018 · Nature Communications · DOI

Full title: Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

Authors: Martens, Christopher R.; Denman, Blair A.; Mazzo, Melissa R.; Armstrong, Michael; Reisdorph, Nichole; McQueen, Matthew B.; Chonchol, Michel; Seals, Douglas R.

Year: 2018

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-018-03421-7

Paper Identification of HSP90 inhibitors as a novel class of senolytics

Heike Fuhrmann-Stroissnigg; Y. Ling; J. Zhao et al. · 2017 · Nature Communications · DOI

Full title: Identification of HSP90 inhibitors as a novel class of senolytics

Authors: Heike Fuhrmann-Stroissnigg; Y. Ling; J. Zhao; S. McGowan; Yi Zhu; R. W. Brooks; D. Grassi; Siobhán Q. Gregg; Jennifer L. Stripay; A. Dorronsoro; L. Corbo; P. Tang; Christina Bukata; N. Ring; M. Giacca; Xuesen Li; T. Tchkonia; J. Kirkland; L. Niedernhofer; P. Robbins

Year: 2017

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-017-00314-z

Paper DNA methylation aging and transcriptomic studies in horses

S. Horvath; A. Haghani; S. Peng et al. · 2021 · bioRxiv · DOI

Full title: DNA methylation aging and transcriptomic studies in horses

Authors: S. Horvath; A. Haghani; S. Peng; E. Hales; J. Zoller; K. Raj; B. Larison; J. Petersen; R. Bellone; C. J. Finno

Year: 2021

Venue: bioRxiv

DOI: https://doi.org/10.1101/2021.03.11.435032

Paper Serotonin and dopamine modulate aging in response to food odor and availability

Hillary A. Miller; Shijiao Huang; Elizabeth S. Dean et al. · 2022 · Nature Communications · DOI

Full title: Serotonin and dopamine modulate aging in response to food odor and availability

Authors: Hillary A. Miller; Shijiao Huang; Elizabeth S. Dean; Megan L. Schaller; Angela M Tuckowski; Allyson S. Munneke; S. Beydoun; S. Pletcher; S. Leiser

Year: 2022

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-022-30869-5

Paper Unsupervised learning of aging principles from longitudinal data

K. Avchaciov; M. Antoch; E. L. Andrianova et al. · 2022 · Nature Communications · DOI

Full title: Unsupervised learning of aging principles from longitudinal data

Authors: K. Avchaciov; M. Antoch; E. L. Andrianova; A. Tarkhov; L. I. Menshikov; O. Burmistrova; A. Gudkov; P. Fedichev

Year: 2022

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-022-34051-9

Paper ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1

Statzer, Cyril; Jin, Meng; Venz, Richard et al. · 2022 · Nature Communications · DOI

Full title: ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1

Authors: Statzer, Cyril; Jin, Meng; Venz, Richard; Bland, Monet S.; Robida-Stubbs, Stacey; Patel, Krina K.; Petrovic, Dunja; Emsley, Raffaella; Liu, Pengpeng; Morantte, Ianessa; Haynes, Cole M.; Mair, William B.; Longchamp, Alban; Filipović, Miloš R.; Blackwell, T. Keith; Ewald, Collin Y.

Year: 2022

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-022-28599-9

Paper Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.

Fan, Shengjie; Yan, Yingxuan; Xia, Ying et al. · 2023 · Nature communications · DOI

Full title: Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.

Authors: Fan, Shengjie; Yan, Yingxuan; Xia, Ying; Zhou, Zhenyu; Luo, Lingling; Zhu, Mengnan; Han, Yongli; Yao, Deqiang; Zhang, Lijun; Fang, Minglv; Peng, Lina; Yu, Jing; Liu, Ying; Gao, Xiaoyan; Guan, Huida; Li, Hongli; Wang, Changhong; Wu, Xiaojun; Zhu, Huanhu; Cao, Yu; Huang, Cheng

Year: 2023

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-023-39118-9

Paper A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice.

Sun, Jie; Wang, Ming; Zhong, Yaqi et al. · 2022 · Nature communications · DOI

Full title: A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice.

Authors: Sun, Jie; Wang, Ming; Zhong, Yaqi; Ma, Xuan; Sun, Shimin; Xu, Chenzhong; Peng, Linyuan; Li, Guo; Zhang, Liting; Liu, Zuojun; Ai, Ding; Liu, Baohua

Year: 2022

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-022-34801-9

Paper TGH: Trans-Generational Hormesis and the Inheritance of Aging Resistance

Fang, Ng Li; Suresh, Jahnavi; Chaithanya, Krishna et al. · 2017 · DOI

Full title: TGH: Trans-Generational Hormesis and the Inheritance of Aging Resistance

Authors: Fang, Ng Li; Suresh, Jahnavi; Chaithanya, Krishna; Linfan, Xiao; Tan, Tuan Zea; Gruber, Jan; Tolwinski, Nicholas S.

Year: 2017

DOI: https://doi.org/10.1101/127951

Paper Superposition of survival curves as a tool for epistasis analysis of longevity interventions

S. Nowak; Johannes Neidhart; Jonas Rzezonka et al. · 2017 · bioRxiv · DOI

Full title: Superposition of survival curves as a tool for epistasis analysis of longevity interventions

Authors: S. Nowak; Johannes Neidhart; Jonas Rzezonka; I. Szendro; Rahul Marathe; J. Krug

Year: 2017

Venue: bioRxiv

DOI: https://doi.org/10.1101/147173

Paper ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants

Kuo, Chia‐Ling; Pilling, Luke C.; Atkins, Janice L. et al. · 2020 · DOI

Full title: ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants

Authors: Kuo, Chia‐Ling; Pilling, Luke C.; Atkins, Janice L.; Kuchel, George A.; Melzer, David

Year: 2020

DOI: https://doi.org/10.1101/2020.02.12.20022459

Paper Reversing age: dual species measurement of epigenetic age with a single clock

Horvath, Steve; Singh, Kavita; Raj, Ken et al. · 2020 · DOI

Full title: Reversing age: dual species measurement of epigenetic age with a single clock

Authors: Horvath, Steve; Singh, Kavita; Raj, Ken; Khairnar, Shraddha I.; Sanghavi, Akshay; Shrivastava, Agnivesh; Zoller, Joseph A.; Li, Caesar Z.; Hereñú, Claudia Beatriz; Canatelli-Mallat, Martina; Lehmann, Marianne; Woods, Leah C. Solberg; Martinez, Angel Garcia; Wang, Tengfei; Chiavellini, Priscila; Levine, Andrew J.; Chen, Hao; Goya, Rodolfo G.; Katcher, Harold L.

Year: 2020

DOI: https://doi.org/10.1101/2020.05.07.082917

Paper Multi-faceted deregulation of gene expression and protein synthesis with age

Anisimova, Aleksandra S.; Meerson, Mark; Gerashchenko, Maxim V. et al. · 2020 · DOI

Full title: Multi-faceted deregulation of gene expression and protein synthesis with age

Authors: Anisimova, Aleksandra S.; Meerson, Mark; Gerashchenko, Maxim V.; Kulakovskiy, Ivan V.; Dmitriev, Sergey E.; Gladyshev, Vadim N.

Year: 2020

DOI: https://doi.org/10.1101/2020.01.19.911404

Paper Epigenetic age-predictions in mice using pyrosequencing, droplet digital PCR or barcoded bisulfite amplicon sequencing

Han, Yang; Nikolić, Miloš; Gobs, Michael et al. · 2020 · DOI

Full title: Epigenetic age-predictions in mice using pyrosequencing, droplet digital PCR or barcoded bisulfite amplicon sequencing

Authors: Han, Yang; Nikolić, Miloš; Gobs, Michael; Franzen, Julia; Haan, Gerald de; Geiger, Hartmut; Wagner, Wolfgang

Year: 2020

DOI: https://doi.org/10.1101/2020.07.30.228122

Paper Cellular aging in vitro recapitulates multi-tissue epigenetic aging in vivo

Christopher J Minteer; M. Morselli; Margarita V. Meer et al. · 2021 · DOI

Full title: Cellular aging in vitro recapitulates multi-tissue epigenetic aging in vivo

Authors: Christopher J Minteer; M. Morselli; Margarita V. Meer; Jian Cao; A. Higgins-Chen; S. Lang; M. Pellegrini; Q. Yan; M. Levine

Year: 2021

DOI: https://doi.org/10.1101/2020.09.02.280073

Paper Observation of the Transport and Removal of Lipofuscin from the Mouse Myocardium using Transmission Electron Microscope

Lei Wang; C.‐Y. Xiao; Jia-Hua Li et al. · 2020 · bioRxiv · DOI

Full title: Observation of the Transport and Removal of Lipofuscin from the Mouse Myocardium using Transmission Electron Microscope

Authors: Lei Wang; C.‐Y. Xiao; Jia-Hua Li; Gui-Cheng Tang; Shuo-Shuang Xiao

Year: 2020

Venue: bioRxiv

DOI: https://doi.org/10.1101/2020.03.10.985507

Paper Epigenetic clock and methylation studies in vervet monkeys

Jasinska, Anna J.; Haghani, Amin; Zoller, Joseph A. et al. · 2021 · GeroScience · DOI

Full title: Epigenetic clock and methylation studies in vervet monkeys

Year: 2021

Venue: GeroScience

Paper The landscape of longevity across phylogeny

D. Podolskiy; Andrei S. Avanesov; A. Tyshkovskiy et al. · 2020 · bioRxiv · DOI

Full title: The landscape of longevity across phylogeny

Authors: D. Podolskiy; Andrei S. Avanesov; A. Tyshkovskiy; Emily Porter; M. Petrascheck; M. Kaeberlein; V. Gladyshev

Year: 2020

Venue: bioRxiv

DOI: https://doi.org/10.1101/2020.03.17.995993

Paper Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity.

Schachtschneider, Kyle M; Schook, Lawrence B; Meudt, Jennifer J et al. · 2021 · GeroScience · DOI

Full title: Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity.

Authors: Schachtschneider, Kyle M; Schook, Lawrence B; Meudt, Jennifer J; Shanmuganayagam, Dhanansayan; Zoller, Joseph A; Haghani, Amin; Li, Caesar Z; Zhang, Joshua; Yang, Andrew; Raj, Ken; Horvath, Steve

Year: 2021

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-021-00439-6

Paper Epigenetic clock and methylation studies in the rhesus macaque

Horvath, Steve; Zoller, Joseph A.; Haghani, Amin et al. · 2021 · GeroScience · DOI

Full title: Epigenetic clock and methylation studies in the rhesus macaque

Authors: Horvath, Steve; Zoller, Joseph A.; Haghani, Amin; Jasinska, Anna J.; Raj, Ken; Breeze, Charles E.; Ernst, Jason; Vaughan, Kelli L.; Mattison, Julie A.

Year: 2021

Venue: GeroScience

Paper Geroprotective effects of Aronia melanocarpa fruit extract on Drosophila melanogaster

E. Platonova; N. Zemskaya; M. Shaposhnikov et al. · 2021 · bioRxiv · DOI

Full title: Geroprotective effects of Aronia melanocarpa fruit extract on Drosophila melanogaster

Authors: E. Platonova; N. Zemskaya; M. Shaposhnikov; D. Golubev; Daria V. Kukuman; N. Pakshina; N. Ulyasheva; V. Punegov; S. Patov; A. Moskalev

Year: 2021

Venue: bioRxiv

DOI: https://doi.org/10.1101/2021.03.03.433673

Paper Serotonin and dopamine modulate aging in response to food perception and availability

Hillary A. Miller; Shijiao Huang; Megan L. Schaller et al. · 2021 · bioRxiv · DOI

Full title: Serotonin and dopamine modulate aging in response to food perception and availability

Authors: Hillary A. Miller; Shijiao Huang; Megan L. Schaller; Elizabeth S. Dean; Angela M Tuckowski; Allyson S. Munneke; S. Beydoun; S. Pletcher; S. Leiser

Year: 2021

Venue: bioRxiv

DOI: https://doi.org/10.1101/2021.03.23.436516

Paper Youthful and age-related matreotypes predict drugs promoting longevity.

Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X et al. · 2021 · Aging cell · DOI

Full title: Youthful and age-related matreotypes predict drugs promoting longevity.

Authors: Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X; Dakhovnik, Alexander; Wandrey, Franziska; Mozharovskyi, Pavlo; Zülli, Fred; Ewald, Collin Y

Year: 2021

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13441

Paper DNA methylation age analysis of rapamycin in common marmosets

Horvath, Steve; Zoller, Joseph A.; Haghani, Amin et al. · 2021 · GeroScience · DOI

Full title: DNA methylation age analysis of rapamycin in common marmosets

Authors: Horvath, Steve; Zoller, Joseph A.; Haghani, Amin; Lu, Ake T.; Raj, Ken; Jasinska, Anna J.; Mattison, Julie A.; Salmon, Adam B.

Year: 2021

Venue: GeroScience

Paper A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking

Higgins‐Chen, Albert; Thrush, Kyra; Wang, Yunzhang et al. · 2021 · DOI

Full title: A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking

Authors: Higgins‐Chen, Albert; Thrush, Kyra; Wang, Yunzhang; Kuo, Pei‐Lun; Wang, Meng; Minteer, Christopher J.; Moore, Ann Zenobia; Bandinelli, Stefania; Vinkers, Christiaan H.; Vermetten, Eric; Rutten, Bart P. F.; Geuze, Elbert; Okhuijsen‐Pfeifer, Cynthia; Horst, Marte van der; Schreiter, Stefanie; Gutwinski, Stefan; Luykx, Jurjen J.; Ferrucci, Luigi; Crimmins, Eileen M.; Boks, Marco P.; Hägg, Sara; Hu-Seliger, T.; Levine, Morgan E.

Year: 2021

DOI: https://doi.org/10.1101/2021.04.16.440205

Paper Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Statzer, Cyril; Reichert, Peter; Dual, Jürg et al. · 2021 · DOI

Full title: Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Authors: Statzer, Cyril; Reichert, Peter; Dual, Jürg; Ewald, Collin Y.

Year: 2021

DOI: https://doi.org/10.1101/2021.05.31.446397

Paper DNA Methylation Networks Underlying Mammalian Traits

A. Haghani; A. Lu; C.Z. Li et al. · 2021 · bioRxiv · DOI

Full title: DNA Methylation Networks Underlying Mammalian Traits

Authors: A. Haghani; A. Lu; C.Z. Li; T. Robeck; K. Belov; C. Breeze; R. Brooke; S. Clarke; C. Faulkes; Z. Fei; S. Ferguson; C. J. Finno; V. Gladyshev; V. Gorbunova; R. Goya; A. Hogan; C. Hogg; T. Hore; H. Kiaris; P. Kordowitzki; G. Banks; W. Koski; K. Mozhui; A. Naderi; E. Ostrander; K. Parsons; J. Plassais; J. Robbins; K. Sears; A. Seluanov; K. Steinman; B. Szladovits; M. Thompson; D. Villar; N. Wang; G. Wilkinson; B. Young; J. Zhang; J. Zoller; J. Ernst; X.W. Yang; K. Raj; S. Horvath

Year: 2021

Venue: bioRxiv

DOI: https://doi.org/10.1101/2021.03.16.435708

Paper Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Ke, Shanlin; Mitchell, Sarah J.; MacArthur, Michael R. et al. · 2021 · Nutrients · DOI

Full title: Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Authors: Ke, Shanlin; Mitchell, Sarah J.; MacArthur, Michael R.; Kane, Alice E.; Sinclair, David; Venable, Emily M.; Chadaideh, Katia S.; Carmody, Rachel N.; Grodstein, Francine; Mitchell, James R.; Liu, Yang‐Yu

Year: 2021

Venue: Nutrients

Paper Epigenetic clock and methylation studies in dogs

Horvath, Steve; Lu, Ake T.; Haghani, Amin et al. · 2021 · DOI

Full title: Epigenetic clock and methylation studies in dogs

Authors: Horvath, Steve; Lu, Ake T.; Haghani, Amin; Zoller, Joseph A.; Brooke, Robert T.; Raj, Ken; Plassais, Jocelyn; Hogan, Andrew N.; Ostrander, Elaine A.

Year: 2021

DOI: https://doi.org/10.1101/2021.03.30.437604

Paper Cost-effective epigenetic age profiling in shallow methylation sequencing data

Trapp, Alexandre; Gladyshev, Vadim N. · 2021 · DOI

Full title: Cost-effective epigenetic age profiling in shallow methylation sequencing data

Authors: Trapp, Alexandre; Gladyshev, Vadim N.

Year: 2021

DOI: https://doi.org/10.1101/2021.10.25.465778

Paper Machine-learning-based predictions of caloric restriction associations across ageing-related genes

G. D. Vega-Magdaleno; V. Bespalov; Yaling Zheng et al. · 2021 · bioRxiv · DOI

Full title: Machine-learning-based predictions of caloric restriction associations across ageing-related genes

Authors: G. D. Vega-Magdaleno; V. Bespalov; Yaling Zheng; A. Freitas; J. de Magalhães

Year: 2021

Venue: bioRxiv

DOI: https://doi.org/10.1101/2021.07.17.452785

Paper Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.

Liu, Yingjun; Senatore, Assunta; Sorce, Silvia et al. · 2022 · Communications biology · DOI

Full title: Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.

Authors: Liu, Yingjun; Senatore, Assunta; Sorce, Silvia; Nuvolone, Mario; Guo, Jingjing; Gümüş, Zeynep H; Aguzzi, Adriano

Year: 2022

Venue: Communications biology

Paper Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans

Bennett, Dominic; Goyala, Anita; Statzer, Cyril et al. · 2021 · DOI

Full title: Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans

Authors: Bennett, Dominic; Goyala, Anita; Statzer, Cyril; Beckett, Charles W.; Tyshkovskiy, Alexander; Gladyshev, Vadim N.; Ewald, Collin Y.; Magalhães, João Pedro de

Year: 2021

DOI: https://doi.org/10.1101/2021.10.13.464294

Paper Divergent age-related methylation patterns in long and short-lived mammals

Haghani, Amin; Wang, Nan; Lu, Ake T et al. · 2022 · DOI

Full title: Divergent age-related methylation patterns in long and short-lived mammals

Authors: Haghani, Amin; Wang, Nan; Lu, Ake T; Mozhui, Khyobeni; Raj, Ken; Yang, Xia; Horvath, Steve

Year: 2022

DOI: https://doi.org/10.1101/2022.01.16.476530

Paper PRC2 clock: a universal epigenetic biomarker of aging and rejuvenation

M. Moqri; A. Cipriano; D. Nachun et al. · 2022 · bioRxiv · DOI

Full title: PRC2 clock: a universal epigenetic biomarker of aging and rejuvenation

Authors: M. Moqri; A. Cipriano; D. Nachun; Tara Murty; Guilherme de Sena Brandine; S. Rasouli; A. Tarkhov; K. Åberg; E. van den Oord; Wanding Zhou; Andrew Smith; C. Mackall; V. Gladyshev; S. Horvath; M. Snyder; V. Sebastiano

Year: 2022

Venue: bioRxiv

DOI: https://doi.org/10.1101/2022.06.03.494609

Paper Novel feature selection methods for construction of accurate epigenetic clocks.

Li, Adam; Mueller, Amber; English, Brad et al. · 2022 · PLoS computational biology · DOI

Full title: Novel feature selection methods for construction of accurate epigenetic clocks.

Authors: Li, Adam; Mueller, Amber; English, Brad; Arena, Anthony; Vera, Daniel; Kane, Alice E; Sinclair, David A

Year: 2022

Venue: PLoS computational biology

Paper Rapamycin treatment during development extends lifespan and healthspan

A. Shindyapina; Yongmin Cho; Alaattin Kaya et al. · 2022 · bioRxiv · DOI

Full title: Rapamycin treatment during development extends lifespan and healthspan

Authors: A. Shindyapina; Yongmin Cho; Alaattin Kaya; A. Tyshkovskiy; J. Castro; Juozas Gordevičius; J. Poganik; S. Horvath; L. Peshkin; V. Gladyshev

Year: 2022

Venue: bioRxiv

DOI: https://doi.org/10.1101/2022.02.18.481092

Paper Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human

Perez-Correa, Juan; Tharmapalan, Vithurithra; Geiger, Hartmut et al. · 2022 · DOI

Full title: Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human

Authors: Perez-Correa, Juan; Tharmapalan, Vithurithra; Geiger, Hartmut; Wagner, Wolfgang

Year: 2022

DOI: https://doi.org/10.1101/2022.03.23.485470

Paper Age related disorder in DNA methylation patterns underlies epigenetic clock signals, but displays distinct responses to epigenetic rejuvenation events

Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B. · 2022 · DOI

Full title: Age related disorder in DNA methylation patterns underlies epigenetic clock signals, but displays distinct responses to epigenetic rejuvenation events

Authors: Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B.

Year: 2022

DOI: https://doi.org/10.1101/2022.12.01.518745

Paper Age-associated sleep-wake patterns are altered with Prdm13 signaling in the dorsomedial hypothalamus and dietary restriction in mice

Shogo Tsuji; Cynthia S. Brace; Ruiqing Yao et al. · 2022 · bioRxiv · DOI

Full title: Age-associated sleep-wake patterns are altered with Prdm13 signaling in the dorsomedial hypothalamus and dietary restriction in mice

Authors: Shogo Tsuji; Cynthia S. Brace; Ruiqing Yao; Yoshitaka Tanie; Hirobumi Tada; N. Rensing; S. Mizuno; Julio Almunia; Yingyi Kong; Kazuhiro Nakamura; Noboru Ogiso; S. Toyokuni; Satoru Takahashi; M. Wong; S. Imai; A. Satoh

Year: 2022

Venue: bioRxiv

DOI: https://doi.org/10.1101/2022.09.26.509442

Paper Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis

Phillips, Eleanor J.; Simons, Mirre J. P. · 2022 · GeroScience · DOI

Full title: Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis

Authors: Phillips, Eleanor J.; Simons, Mirre J. P.

Year: 2022

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00691-4

Paper Single cell DNA methylation ageing in mouse blood

Bonder, Marc Jan; Clark, Stephen J.; Krueger, Felix et al. · 2023 · DOI

Full title: Single cell DNA methylation ageing in mouse blood

Authors: Bonder, Marc Jan; Clark, Stephen J.; Krueger, Felix; Luo, Siyuan; Sousa, João Agostinho de; Hashtroud, Aida M.; Stubbs, Thomas M.; Stark, Anne‐Katrien; Rulands, Steffen; Stegle, Oliver; Reik, Wolf; Meyenn, Ferdinand von

Year: 2023

DOI: https://doi.org/10.1101/2023.01.30.526343

Paper Preservation of Mitochondrial Membrane Potential is Necessary for Lifespan Extension from Dietary Restriction

Berry, Brandon; Mjelde, Evan; Carreno, Fatima et al. · 2022 · DOI

Full title: Preservation of Mitochondrial Membrane Potential is Necessary for Lifespan Extension from Dietary Restriction

Authors: Berry, Brandon; Mjelde, Evan; Carreno, Fatima; Gilham, Kathryn; Hanson, Emily J.; Na, Emily; Kaeberlein, Matt

Year: 2022

DOI: https://doi.org/10.1101/2022.12.27.522028

Paper In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers

Parinya Samakkarnthai; D. Saul; Lei Zhang et al. · 2023 · bioRxiv · DOI

Full title: In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers

Authors: Parinya Samakkarnthai; D. Saul; Lei Zhang; Zaira Aversa; Madison L. Doolittle; J. Sfeir; Japneet Kaur; Elizabeth J. Atkinson; James R. Edwards; R. G. Russell; R. Pignolo; James L Kirkland; T. Tchkonia; L. Niedernhofer; D. Monroe; N. LeBrasseur; J. Farr; Paul D. Robbins; Sundeep Khosla

Year: 2023

Venue: bioRxiv

DOI: https://doi.org/10.1101/2023.02.23.529777

Paper Region-Based Epigenetic Clock Design Improves RRBS-Based Age Prediction

Simpson, Daniel J.; Zhao, Qian; Olova, Nelly et al. · 2023 · DOI

Full title: Region-Based Epigenetic Clock Design Improves RRBS-Based Age Prediction

Authors: Simpson, Daniel J.; Zhao, Qian; Olova, Nelly; Dabrowski, Jan; Xie, Xiaoxiao; Latorre‐Crespo, Eric; Chandra, Tamir

Year: 2023

DOI: https://doi.org/10.1101/2023.01.13.524017

Paper Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies

Gao, Shihong Max; Qi, Yanyan; Zhang, Qinghao et al. · 2023 · DOI

Full title: Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies

Authors: Gao, Shihong Max; Qi, Yanyan; Zhang, Qinghao; Mohammed, Aaron; Lee, Yi-Tang; Guan, Youchen; Li, Hongjie; Fu, Yusi; Wang, Meng C.

Year: 2023

DOI: https://doi.org/10.1101/2023.02.28.530490

Paper Compression of morbidity by interventions that steepen the survival curve.

Yang, Yifan; Mayo, Avi; Levy, Tomer et al. · 2025 · Nature communications · DOI

Full title: Compression of morbidity by interventions that steepen the survival curve.

Authors: Yang, Yifan; Mayo, Avi; Levy, Tomer; Raz, Naveh; Shenhar, Ben; Jarosz, Daniel F; Alon, Uri

Year: 2025

Venue: Nature communications

Paper Quantification of healthspan in aging mice: Introducing FAMY and GRAIL

Lamming, Dudley W. · 2023 · DOI

Full title: Quantification of healthspan in aging mice: Introducing FAMY and GRAIL

Authors: Lamming, Dudley W.

Year: 2023

DOI: https://doi.org/10.1101/2023.11.07.566044

Paper The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride.

Jiang, Nisi; Gelfond, Jonathan; Liu, Qianqian et al. · 2024 · GeroScience · DOI

Full title: The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride.

Authors: Jiang, Nisi; Gelfond, Jonathan; Liu, Qianqian; Strong, Randy; Nelson, James F

Year: 2024

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01161-9

Paper Establishing healthy longevity clinics in publicly funded hospitals

Bonnes, Sara L.; Strauss, Tzipora; Palmer, Allyson K. et al. · 2024 · GeroScience · DOI

Full title: Establishing healthy longevity clinics in publicly funded hospitals

Authors: Bonnes, Sara L.; Strauss, Tzipora; Palmer, Allyson K.; Hurt, Ryan T.; Island, Louis; Goshen, Abigail; Wang, Laureen; Kirkland, James L.; Bischof, Evelyne; Maier, Andrea B.

Year: 2024

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01132-0

Paper Testing the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim.

Sandalova, E; Li, H; Guan, L et al. · 2024 · GeroScience · DOI

Full title: Testing the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim.

Authors: Sandalova, E; Li, H; Guan, L; Raj, S D; Lim, T G; Tian, E; Kennedy, B K; Maier, A B

Year: 2024

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01257-2

Paper Senolytic intervention improves cognition, metabolism, and adiposity in female APPNL-F/NL-F mice.

Fang, Yimin; Peck, Mackenzie R; Quinn, Kathleen et al. · 2025 · GeroScience · DOI

Full title: Senolytic intervention improves cognition, metabolism, and adiposity in female APPNL-F/NL-F mice.

Authors: Fang, Yimin; Peck, Mackenzie R; Quinn, Kathleen; Chapman, Jenelle E; Medina, David; McFadden, Samuel A; Bartke, Andrzej; Hascup, Erin R; Hascup, Kevin N

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01308-8

Paper Ndufs4-/- mice: a testing ground for longevity interventions.

Nuss, Jackson; Kaeberlein, Matt; Bitto, Alessandro et al. · 2025 · GeroScience · DOI

Full title: Ndufs4-/- mice: a testing ground for longevity interventions.

Authors: Nuss, Jackson; Kaeberlein, Matt; Bitto, Alessandro; Grillo, Anthony S

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-01704-8

Paper EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework

Haghani, Amin; Lu, Ake T; Yan, Qi et al. · 2025 · GeroScience · DOI

Full title: EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework

Authors: Haghani, Amin; Lu, Ake T; Yan, Qi; Belmonte, Juan Carlos Izpisúa; Reddy, Pradeep; Cheng, Victor; Yang, X. William; Wang, Nan; Mozhui, Khyobeni; Murach, Kevin A.; Ocampo, Alejandro; Williams, Robert W.; Jucker, Mathias; Bergmann, Carina; Poganik, Jesse R.; Zhang, Bohan; Gladyshev, Vadim N.; Horvath, Steve

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-01808-1

Paper Adaptations of mitochondrial, autophagy and nutrient sensing pathways in the liver from long-lived mice overexpressing CYB5R3 are sex-dependent and involve inter-organ responses

Sánchez‐Mendoza, Luz Marina; González‐Reyes, José A.; López, Sandra et al. · 2025 · GeroScience · DOI

Full title: Adaptations of mitochondrial, autophagy and nutrient sensing pathways in the liver from long-lived mice overexpressing CYB5R3 are sex-dependent and involve inter-organ responses

Authors: Sánchez‐Mendoza, Luz Marina; González‐Reyes, José A.; López, Sandra; García‐Caballero, Cristina; Moreno, Juan Antonio; Cabo, Rafael de; Burón, María I.; Villalba, José M.

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-01761-z

Paper Discrimination of normal from slow-aging mice by plasma metabolomic and proteomic features.

Badenoch, Bretton; Fiehn, Oliver; Rappaport, Noa et al. · 2025 · GeroScience · DOI

Full title: Discrimination of normal from slow-aging mice by plasma metabolomic and proteomic features.

Authors: Badenoch, Bretton; Fiehn, Oliver; Rappaport, Noa; Srivastava, Pranjal; Watanabe, Kengo; Chandrasekaran, Sriram; Miller, Richard A

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-02028-3

Paper Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

Al-Saadi, Rose S; Phillips, Patrick C · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

Authors: Al-Saadi, Rose S; Phillips, Patrick C

Year: 2025

Venue: bioRxiv : the preprint server for biology

Paper Anti-Aging and Biomedicine: Critical Studies on the Pursuit of Maintaining, Revitalizing and Enhancing Aging Bodies

Kampf, Antje; Botelho, Lynn · 2009 · Medicine Studies · DOI

Full title: Anti-Aging and Biomedicine: Critical Studies on the Pursuit of Maintaining, Revitalizing and Enhancing Aging Bodies

Authors: Kampf, Antje; Botelho, Lynn

Year: 2009

Venue: Medicine Studies

DOI: https://doi.org/10.1007/s12376-009-0021-9

Paper The plasticity of ageing and the rediscovery of ground-state prevention.

Blasimme, Alessandro · 2021 · History and philosophy of the life sciences · DOI

Full title: The plasticity of ageing and the rediscovery of ground-state prevention.

Authors: Blasimme, Alessandro

Year: 2021

Venue: History and philosophy of the life sciences

DOI: https://doi.org/10.1007/s40656-021-00414-6

Paper The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan.

Gkioni, Lisonia; Nespital, Tobias; Baghdadi, Maarouf et al. · 2025 · Nature aging · DOI

Full title: The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan.

Authors: Gkioni, Lisonia; Nespital, Tobias; Baghdadi, Maarouf; Monzó, Carolina; Bali, Jitin; Nassr, Taim; Cremer, Anna Lena; Beyer, Andreas; Deelen, Joris; Backes, Heiko; Grönke, Sebastian; Partridge, Linda

Year: 2025

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-025-00876-4

Paper A new compound that extends the lifespan of worms, with favorable in vitro properties and a lack of toxicity in rodents.

Blank, Heidi M; Polymenis, Michael · 2025 · RSC medicinal chemistry · DOI

Full title: A new compound that extends the lifespan of worms, with favorable in vitro properties and a lack of toxicity in rodents.

Authors: Blank, Heidi M; Polymenis, Michael

Year: 2025

Venue: RSC medicinal chemistry

DOI: https://doi.org/10.1039/d5md00780a

Paper [Senotherapy: Advances and new clinical perspectives].

Damien Véret; J. Brondello · 2020 · Medecine sciences : M/S · DOI

Full title: [Senotherapy: Advances and new clinical perspectives].

Authors: Damien Véret; J. Brondello

Year: 2020

Venue: Medecine sciences : M/S

DOI: https://doi.org/10.1051/medsci/2020220

Paper NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations

Yang, Liang; Ruan, Zifeng; Lin, Xiaobing et al. · 2024 · Nature Communications · DOI

Full title: NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations

Authors: Yang, Liang; Ruan, Zifeng; Lin, Xiaobing; Wang, Hao; Xin, Yanmin; Tang, Haite; Hu, Zhijuan; Zhou, Yunhao; Wu, Yi; Wang, Junwei; Qin, Dajiang; Lü, Gang; Loomes, Kerry M.; Chan, Wai‐Yee; Liu, Xingguo

Year: 2024

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-024-44808-z

Paper PRC2-AgeIndex as a universal biomarker of aging and rejuvenation.

Moqri, Mahdi; Cipriano, Andrea; Simpson, Daniel J et al. · 2024 · Nature communications · DOI

Full title: PRC2-AgeIndex as a universal biomarker of aging and rejuvenation.

Authors: Moqri, Mahdi; Cipriano, Andrea; Simpson, Daniel J; Rasouli, Sajede; Murty, Tara; de Jong, Tineke Anna; Nachun, Daniel; de Sena Brandine, Guilherme; Ying, Kejun; Tarkhov, Andrei; Aberg, Karolina A; van den Oord, Edwin; Zhou, Wanding; Smith, Andrew; Mackall, Crystal; Gladyshev, Vadim N; Horvath, Steve; Snyder, Michael P; Sebastiano, Vittorio

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-50098-2

Paper scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood

Bonder, Marc Jan; Clark, Stephen J.; Krueger, Felix et al. · 2024 · Nature Communications · DOI

Full title: scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood

Year: 2024

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-024-51833-5

Paper Cellular reprogramming as a tool to model human aging in a dish.

Pitrez, Patricia R; Monteiro, Luis M; Borgogno, Oliver et al. · 2024 · Nature communications · DOI

Full title: Cellular reprogramming as a tool to model human aging in a dish.

Authors: Pitrez, Patricia R; Monteiro, Luis M; Borgogno, Oliver; Nissan, Xavier; Mertens, Jerome; Ferreira, Lino

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-024-46004-5

Paper Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.

Teuscher, Alina C; Statzer, Cyril; Goyala, Anita et al. · 2024 · Nature communications · DOI

Full title: Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.

Authors: Teuscher, Alina C; Statzer, Cyril; Goyala, Anita; Domenig, Seraina A; Schoen, Ingmar; Hess, Max; Hofer, Alexander M; Fossati, Andrea; Vogel, Viola; Goksel, Orcun; Aebersold, Ruedi; Ewald, Collin Y

Year: 2024

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-023-44409-2

Paper High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models.

Chen, Li; Wu, Bangfu; Mo, Li et al. · 2025 · Nature communications · DOI

Full title: High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models.

Authors: Chen, Li; Wu, Bangfu; Mo, Li; Chen, Huimin; Yin, Xingzhu; Zhao, Ying; Cui, ZhaoYu; Cui, Feipeng; Chen, Liangkai; Deng, Qianchun; Gao, Chao; Yao, Ping; Li, Yanyan; Tang, Yuhan

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-58188-5

Paper Compression of morbidity by interventions that steepen the survival curve.

Yang, Yifan; Mayo, Avi; Levy, Tomer et al. · 2025 · Nature communications · DOI

Full title: Compression of morbidity by interventions that steepen the survival curve.

Authors: Yang, Yifan; Mayo, Avi; Levy, Tomer; Raz, Naveh; Shenhar, Ben; Jarosz, Daniel F; Alon, Uri

Year: 2025

Venue: Nature communications

Paper The promise of organ rejuvenation to overcome the shortage in organ transplantation.

Kayumov, Mukhammad; Song, Zhuolun; Martin, Friederike et al. · 2025 · Nature communications · DOI

Full title: The promise of organ rejuvenation to overcome the shortage in organ transplantation.

Authors: Kayumov, Mukhammad; Song, Zhuolun; Martin, Friederike; Tsou, Sarah; Xiao, Yao; Zhou, Hao; Tullius, Stefan G

Year: 2025

Venue: Nature communications

DOI: https://doi.org/10.1038/s41467-025-66133-9

Paper Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans

I. M. Hu; M. Molenaars; Yorrick R. J. Jaspers et al. · 2025 · Nature Communications · DOI

Full title: Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans

Authors: I. M. Hu; M. Molenaars; Yorrick R. J. Jaspers; Bauke V. Schomakers; M. van Weeghel; A. Bakker; M. Modder; J. Dewulf; Guido T. Bommer; Arwen W. Gao; Georges E. Janssens; R. Houtkooper

Year: 2025

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-025-61433-6

Paper Sex-specific insights into drug-induced lifespan extension and weight loss in mice

Belikov, Aleksey V.; Talay, Angelo; Magalhães, João Pedro de · 2025 · npj Aging · DOI

Full title: Sex-specific insights into drug-induced lifespan extension and weight loss in mice

Authors: Belikov, Aleksey V.; Talay, Angelo; Magalhães, João Pedro de

Year: 2025

Venue: npj Aging

DOI: https://doi.org/10.1038/s41514-025-00229-w

Paper Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database.

Parish, Austin; Ioannidis, John P A; Zhang, Kevin et al. · 2025 · npj aging · DOI

Full title: Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database.

Authors: Parish, Austin; Ioannidis, John P A; Zhang, Kevin; Barardo, Diogo; R Swindell, William; de Magalhães, João Pedro

Year: 2025

Venue: npj aging

Paper Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice.

Mittal, Nitish; Ataman, Meric; Tintignac, Lionel et al. · 2024 · NPJ Regenerative medicine · DOI

Full title: Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice.

Authors: Mittal, Nitish; Ataman, Meric; Tintignac, Lionel; Ham, Daniel J; Jörin, Lena; Schmidt, Alexander; Sinnreich, Michael; Ruegg, Markus A; Zavolan, Mihaela

Year: 2024

Venue: NPJ Regenerative medicine

DOI: https://doi.org/10.1038/s41536-024-00369-9

Paper Plasma proteomics links brain and immune system aging with healthspan and longevity.

Oh, Hamilton Se-Hwee; Le Guen, Yann; Rappoport, Nimrod et al. · 2025 · Nature medicine · DOI

Full title: Plasma proteomics links brain and immune system aging with healthspan and longevity.

Authors: Oh, Hamilton Se-Hwee; Le Guen, Yann; Rappoport, Nimrod; Urey, Deniz Yagmur; Farinas, Amelia; Rutledge, Jarod; Channappa, Divya; Wagner, Anthony D; Mormino, Elizabeth; Brunet, Anne; Greicius, Michael D; Wyss-Coray, Tony

Year: 2025

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-025-03798-1

Paper Molecular signatures of premature aging in Major Depression and Substance Use Disorders.

Onisiforou, Anna; Zanos, Panos; Georgiou, Polymnia · 2024 · Scientific data · DOI

Full title: Molecular signatures of premature aging in Major Depression and Substance Use Disorders.

Authors: Onisiforou, Anna; Zanos, Panos; Georgiou, Polymnia

Year: 2024

Venue: Scientific data

DOI: https://doi.org/10.1038/s41597-024-03538-z

Paper Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

Zhang, Hongmei; Diaz, Vivian; Walsh, Michael et al. · 2017 · Scientific Reports · DOI

Full title: Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

Authors: Zhang, Hongmei; Diaz, Vivian; Walsh, Michael; Zhang, Yiqiang

Year: 2017

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-017-00970-7

Paper Senolytic effects of quercetin in an in vitro model of pre-adipocytes and adipocytes induced senescence.

Zoico, Elena; Nori, Nicole; Darra, Elena et al. · 2021 · Scientific reports · DOI

Full title: Senolytic effects of quercetin in an in vitro model of pre-adipocytes and adipocytes induced senescence.

Authors: Zoico, Elena; Nori, Nicole; Darra, Elena; Tebon, Maela; Rizzatti, Vanni; Policastro, Gabriella; De Caro, Annamaria; Rossi, Andrea Petronio; Fantin, Francesco; Zamboni, Mauro

Year: 2021

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-021-02544-0

Paper The Na/K-ATPase Oxidant Amplification Loop Regulates Aging.

Sodhi, Komal; Nichols, Alexandra; Mallick, Amrita et al. · 2018 · Scientific reports · DOI

Full title: The Na/K-ATPase Oxidant Amplification Loop Regulates Aging.

Authors: Sodhi, Komal; Nichols, Alexandra; Mallick, Amrita; Klug, Rebecca L; Liu, Jiang; Wang, Xiaoliang; Srikanthan, Krithika; Goguet-Rubio, Perrine; Nawab, Athar; Pratt, Rebecca; Lilly, Megan N; Sanabria, Juan R; Xie, Zijian; Abraham, Nader G; Shapiro, Joseph I

Year: 2018

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-018-26768-9

Paper Dasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice.

Ota, Hidetaka; Kodama, Ayuto · 2022 · Scientific reports · DOI

Full title: Dasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice.

Authors: Ota, Hidetaka; Kodama, Ayuto

Year: 2022

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-022-06448-5

Paper Targeted methods for epigenetic age predictions in mice

Han, Yang; Nikolić, Miloš; Gobs, Michael et al. · 2020 · Scientific Reports · DOI

Full title: Targeted methods for epigenetic age predictions in mice

Authors: Han, Yang; Nikolić, Miloš; Gobs, Michael; Franzen, Julia; Haan, Gerald de; Geiger, Hartmut; Wagner, Wolfgang

Year: 2020

Venue: Scientific Reports

DOI: https://doi.org/10.1038/s41598-020-79509-2

Paper The senolytic drug ABT-263 accelerates ovarian aging in older female mice.

Xia, Xiyang; Yang, Yingying; Liu, Pengfei et al. · 2024 · Scientific reports · DOI

Full title: The senolytic drug ABT-263 accelerates ovarian aging in older female mice.

Authors: Xia, Xiyang; Yang, Yingying; Liu, Pengfei; Chen, Li; Dai, Xiuliang; Xue, Pingping; Wang, Yufeng

Year: 2024

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-024-73828-4

Paper Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.

Liu, Yingjun; Senatore, Assunta; Sorce, Silvia et al. · 2022 · Communications biology · DOI

Full title: Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.

Authors: Liu, Yingjun; Senatore, Assunta; Sorce, Silvia; Nuvolone, Mario; Guo, Jingjing; Gümüş, Zeynep H; Aguzzi, Adriano

Year: 2022

Venue: Communications biology

Paper Modeling treatment of diabetic wounds with oxygen therapy and senolytic drug.

Siewe, Nourridine; Friedman, Avner · 2025 · Scientific reports · DOI

Full title: Modeling treatment of diabetic wounds with oxygen therapy and senolytic drug.

Authors: Siewe, Nourridine; Friedman, Avner

Year: 2025

Venue: Scientific reports

DOI: https://doi.org/10.1038/s41598-025-02852-9

Paper Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging

Fernando, Raquel; Shindyapina, Anastasia V.; Ost, Mario et al. · 2023 · Communications Biology · DOI

Full title: Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging

Authors: Fernando, Raquel; Shindyapina, Anastasia V.; Ost, Mario; Santesmasses, Didac; Hu, Yan; Tyshkovskiy, Alexander; Yim, Sun Hee; Weiß, Jürgen; Gladyshev, Vadim N.; Grune, Tilman; Castro, José Pedro

Year: 2023

Venue: Communications Biology

DOI: https://doi.org/10.1038/s42003-023-05595-3

Paper Biological age estimation using circulating blood biomarkers

Bortz, Jordan; Guariglia, Andrea; Klarić, Lucija et al. · 2023 · Communications Biology · DOI

Full title: Biological age estimation using circulating blood biomarkers

Authors: Bortz, Jordan; Guariglia, Andrea; Klarić, Lucija; Tang, David; Ward, Peter; Geer, Michael R.; Chadeau‐Hyam, Marc; Vuckovic, Dragana; Joshi, Peter K.

Year: 2023

Venue: Communications Biology

DOI: https://doi.org/10.1038/s42003-023-05456-z

Paper Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.

Shaposhnikov, Mikhail V; Guvatova, Zulfiya G; Zemskaya, Nadezhda V et al. · 2022 · Communications biology · DOI

Full title: Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.

Authors: Shaposhnikov, Mikhail V; Guvatova, Zulfiya G; Zemskaya, Nadezhda V; Koval, Liubov A; Schegoleva, Eugenia V; Gorbunova, Anastasia A; Golubev, Denis A; Pakshina, Natalya R; Ulyasheva, Natalia S; Solovev, Ilya A; Bobrovskikh, Margarita A; Gruntenko, Nataly E; Menshanov, Petr N; Krasnov, George S; Kudryavseva, Anna V; Moskalev, Alexey A

Year: 2022

Venue: Communications biology

DOI: https://doi.org/10.1038/s42003-022-03524-4

Paper Benchmarking large language models for personalized, biomarker-based health intervention recommendations.

Jarchow, Hans; Bobrowski, Christoph; Falk, Steffi et al. · 2025 · NPJ digital medicine · DOI

Full title: Benchmarking large language models for personalized, biomarker-based health intervention recommendations.

Authors: Jarchow, Hans; Bobrowski, Christoph; Falk, Steffi; Hermann, Andreas; Kulaga, Anton; Põder, Johann-Christian; Unfried, Maximilian; Usanov, Nikolay; Zendeh, Bijan; Kennedy, Brian K; Lobentanzer, Sebastian; Fuellen, Georg

Year: 2025

Venue: NPJ digital medicine

DOI: https://doi.org/10.1038/s41746-025-01996-2

Paper Single-cell analysis of the aging female mouse hypothalamus

Hajdarovic, Kaitlyn H.; Yu, Doudou; Hassell, Lexi-Amber et al. · 2022 · Nature Aging · DOI

Full title: Single-cell analysis of the aging female mouse hypothalamus

Authors: Hajdarovic, Kaitlyn H.; Yu, Doudou; Hassell, Lexi-Amber; Evans, Shane A.; Packer, Sarah; Neretti, Nicola; Webb, Ashley E.

Year: 2022

Venue: Nature Aging

DOI: https://doi.org/10.1038/s43587-022-00246-4

Paper SGLT2 inhibition eliminates senescent cells and alleviates pathological aging.

Katsuumi, Goro; Shimizu, Ippei; Suda, Masayoshi et al. · 2024 · Nature aging · DOI

Full title: SGLT2 inhibition eliminates senescent cells and alleviates pathological aging.

Authors: Katsuumi, Goro; Shimizu, Ippei; Suda, Masayoshi; Yoshida, Yohko; Furihata, Takaaki; Joki, Yusuke; Hsiao, Chieh-Lun; Jiaqi, Liang; Fujiki, Shinya; Abe, Manabu; Sugimoto, Masataka; Soga, Tomoyoshi; Minamino, Tohru

Year: 2024

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-024-00642-y

Paper Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

Waziry, Reem; Ryan, Calen P.; Corcoran, David L. et al. · 2023 · Nature Aging · DOI

Full title: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

Authors: Waziry, Reem; Ryan, Calen P.; Corcoran, David L.; Huffman, K. M.; Kobor, Michael S.; Kothari, Meeraj; Graf, Gloria Huei-Jong; Kraus, Virginia B.; Kraus, William E.; Lin, David; Pieper, Carl F.; Ramaker, M. E.; Bhapkar, Manjushri; Das, Shilpa; Ferrucci, Luigi; Hastings, W. J.; Kebbe, Maryam; Parker, Daniel; Racette, Susan B.; Shalev, Idan; Schilling, Birgit; Belsky, Daniel W.

Year: 2023

Venue: Nature Aging

DOI: https://doi.org/10.1038/s43587-022-00357-y

Paper Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology.

Aguado, Julio; Amarilla, Alberto A; Taherian Fard, Atefeh et al. · 2023 · Nature aging · DOI

Full title: Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology.

Authors: Aguado, Julio; Amarilla, Alberto A; Taherian Fard, Atefeh; Albornoz, Eduardo A; Tyshkovskiy, Alexander; Schwabenland, Marius; Chaggar, Harman K; Modhiran, Naphak; Gómez-Inclán, Cecilia; Javed, Ibrahim; Baradar, Alireza A; Liang, Benjamin; Peng, Lianli; Dharmaratne, Malindrie; Pietrogrande, Giovanni; Padmanabhan, Pranesh; Freney, Morgan E; Parry, Rhys; Sng, Julian D J; Isaacs, Ariel; Khromykh, Alexander A; Valenzuela Nieto, Guillermo; Rojas-Fernandez, Alejandro; Davis, Thomas P; Prinz, Marco; Bengsch, Bertram; Gladyshev, Vadim N; Woodruff, Trent M; Mar, Jessica C; Watterson, Daniel; Wolvetang, Ernst J

Year: 2023

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-023-00519-6

Paper Inflammaging and Immunosenescence as Part of Skin Aging-A Narrative Review.

Pająk, Justyna; Nowicka, Danuta; Szepietowski, Jacek C · 2023 · International journal of molecular sciences · DOI

Full title: Inflammaging and Immunosenescence as Part of Skin Aging-A Narrative Review.

Authors: Pająk, Justyna; Nowicka, Danuta; Szepietowski, Jacek C

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24097784

Paper Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of Drosophila melanogaster

Y. Vershinina; G. Krasnov; D. Garbuz et al. · 2023 · International Journal of Molecular Sciences · DOI

Full title: Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of Drosophila melanogaster

Authors: Y. Vershinina; G. Krasnov; D. Garbuz; M. Shaposhnikov; M. Fedorova; E. Pudova; I. Katunina; A. Kornev; N. Zemskaya; A. Kudryavtsev; E. Bulavkina; A. A. Matveeva; N. Ulyasheva; Z. Guvatova; Artemiy A Anurov; A. Moskalev; A. Kudryavtseva

Year: 2023

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms24109095

Paper Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies.

Ya, Jingyuan; Bayraktutan, Ulvi · 2023 · International journal of molecular sciences · DOI

Full title: Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies.

Authors: Ya, Jingyuan; Bayraktutan, Ulvi

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms241411538

Paper Accelerated Aging in Cancer Survivors: Cellular Senescence, Frailty, and Possible Opportunities for Interventions.

Wang, Shuo; El Jurdi, Najla; Thyagarajan, Bharat et al. · 2024 · International journal of molecular sciences · DOI

Full title: Accelerated Aging in Cancer Survivors: Cellular Senescence, Frailty, and Possible Opportunities for Interventions.

Authors: Wang, Shuo; El Jurdi, Najla; Thyagarajan, Bharat; Prizment, Anna; Blaes, Anne H

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms25063319

Paper The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines.

Sax, Scott L; Centomo, Maria Laura; Centofanti, Federica et al. · 2024 · International journal of molecular sciences · DOI

Full title: The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines.

Authors: Sax, Scott L; Centomo, Maria Laura; Centofanti, Federica; Rizzacasa, Barbara; Cox, Sierra; Cox, Chelsea; Latini, Andrea; D'Apice, Maria Rosaria; Mannucci, Liliana; Novelli, Giuseppe; Pandolfi, Pier Paolo

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms252111652

Paper The Critical Role of Autophagy and Phagocytosis in the Aging Brain

Bondy, Stephen C.; Wu, Meixia · 2024 · International Journal of Molecular Sciences · DOI

Full title: The Critical Role of Autophagy and Phagocytosis in the Aging Brain

Authors: Bondy, Stephen C.; Wu, Meixia

Year: 2024

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms26010057

Paper Exploring Senolytic and Senomorphic Properties of Medicinal Plants for Anti-Aging Therapies.

Imb, Monika; Véghelyi, Zsolt; Maurer, Michael et al. · 2024 · International journal of molecular sciences · DOI

Full title: Exploring Senolytic and Senomorphic Properties of Medicinal Plants for Anti-Aging Therapies.

Authors: Imb, Monika; Véghelyi, Zsolt; Maurer, Michael; Kühnel, Harald

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms251910419

Paper Transcranial Electromagnetic Wave Treatment: A Fountain of Healthy Longevity?

Arendash, Gary; Cao, Chuanhai · 2023 · International journal of molecular sciences · DOI

Full title: Transcranial Electromagnetic Wave Treatment: A Fountain of Healthy Longevity?

Authors: Arendash, Gary; Cao, Chuanhai

Year: 2023

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms24119652

Paper In Silico Assessment of Potential Geroprotectors: From Separate Endpoints to Complex Pharmacotherapeutic Effects.

Stolbov, Leonid; Rudik, Anastasia; Lagunin, Alexey et al. · 2025 · International journal of molecular sciences · DOI

Full title: In Silico Assessment of Potential Geroprotectors: From Separate Endpoints to Complex Pharmacotherapeutic Effects.

Authors: Stolbov, Leonid; Rudik, Anastasia; Lagunin, Alexey; Druzhilovskiy, Dmitry; Filimonov, Dmitry; Poroikov, Vladimir

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26188858

Paper Dermal Fibroblast Senescence: The Central Hub of Skin Aging—From Intrinsic Dysfunction to Microenvironmental Remodeling

Jinyu Zheng; Sensen Wang; Jiaming Sun et al. · 2026 · International Journal of Molecular Sciences · DOI

Full title: Dermal Fibroblast Senescence: The Central Hub of Skin Aging—From Intrinsic Dysfunction to Microenvironmental Remodeling

Authors: Jinyu Zheng; Sensen Wang; Jiaming Sun; Jingwei Lv

Year: 2026

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms27041653

Paper Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy.

Delrue, Charlotte; Speeckaert, Reinhart; Speeckaert, Marijn M · 2025 · International journal of molecular sciences · DOI

Full title: Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy.

Authors: Delrue, Charlotte; Speeckaert, Reinhart; Speeckaert, Marijn M

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26199372

Paper Epigenetic Clock and Circadian Rhythms in Stem Cell Aging and Rejuvenation

Samoilova, Ekaterina M.; Belopasov, Vladimir V.; Ekusheva, Evgenia V. et al. · 2021 · Journal of Personalized Medicine · DOI

Full title: Epigenetic Clock and Circadian Rhythms in Stem Cell Aging and Rejuvenation

Authors: Samoilova, Ekaterina M.; Belopasov, Vladimir V.; Ekusheva, Evgenia V.; Zhang, Chao; Troitskiy, A. V.; Баклаушев, Владимир П.

Year: 2021

Venue: Journal of Personalized Medicine

DOI: https://doi.org/10.3390/jpm11111050

Paper Senotherapeutics for Brain Aging Management.

Saliev, Timur; Singh, Prim B · 2025 · Neurology international · DOI

Full title: Senotherapeutics for Brain Aging Management.

Authors: Saliev, Timur; Singh, Prim B

Year: 2025

Venue: Neurology international

DOI: https://doi.org/10.3390/neurolint17120204

Paper Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs.

Li, Jinjun; Zhao, Kai; Yang, Guotai et al. · 2025 · Molecules (Basel, Switzerland) · DOI

Full title: Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs.

Authors: Li, Jinjun; Zhao, Kai; Yang, Guotai; Lv, Haohao; Zhang, Renxin; Li, Shuhan; Chen, Zhiyuan; Xu, Min; Yang, Naixue; Dai, Shaoxing

Year: 2025

Venue: Molecules (Basel, Switzerland)

DOI: https://doi.org/10.3390/molecules30122653

Paper Cholesterol versus Inflammation as Cause of Chronic Diseases

Panchal, Sunil K.; Brown, Lindsay · 2019 · Nutrients · DOI

Full title: Cholesterol versus Inflammation as Cause of Chronic Diseases

Authors: Panchal, Sunil K.; Brown, Lindsay

Year: 2019

Venue: Nutrients

DOI: https://doi.org/10.3390/nu11102332

Paper Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Ke, Shanlin; Mitchell, Sarah J.; MacArthur, Michael R. et al. · 2021 · Nutrients · DOI

Full title: Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Year: 2021

Venue: Nutrients

DOI: https://doi.org/10.36948/ijfmr.2024.v06i03.22349

Paper Effects of Parental Dietary Restriction on Offspring Fitness in Drosophila melanogaster

Lee, Hye‐Yeon; Lee, Bora; Lee, Eun‐Ji et al. · 2023 · Nutrients · DOI

Full title: Effects of Parental Dietary Restriction on Offspring Fitness in Drosophila melanogaster

Authors: Lee, Hye‐Yeon; Lee, Bora; Lee, Eun‐Ji; Min, Kyung‐Jin

Year: 2023

Venue: Nutrients

DOI: https://doi.org/10.3390/nu15051273

Paper The Potential of Calorie Restriction and Calorie Restriction Mimetics in Delaying Aging: Focus on Experimental Models.

Giacomello, Emiliana; Toniolo, Luana · 2021 · Nutrients · DOI

Full title: The Potential of Calorie Restriction and Calorie Restriction Mimetics in Delaying Aging: Focus on Experimental Models.

Authors: Giacomello, Emiliana; Toniolo, Luana

Year: 2021

Venue: Nutrients

DOI: https://doi.org/10.3390/nu13072346

Paper Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults.

Wang, Shuyue; Song, Lixia; Fan, Rui et al. · 2024 · Nutrients · DOI

Full title: Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults.

Authors: Wang, Shuyue; Song, Lixia; Fan, Rui; Chen, Qianqian; You, Mei; Cai, Meng; Wu, Yuxiao; Li, Yong; Xu, Meihong

Year: 2024

Venue: Nutrients

DOI: https://doi.org/10.3390/nu16091343

Paper Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan.

Sharma, Arastu; Chabloz, Sophie; Lapides, Rebecca A et al. · 2023 · Nutrients · DOI

Full title: Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan.

Authors: Sharma, Arastu; Chabloz, Sophie; Lapides, Rebecca A; Roider, Elisabeth; Ewald, Collin Y

Year: 2023

Venue: Nutrients

DOI: https://doi.org/10.3390/nu15020445

Paper Unveiling the Anti-Aging Potential of 3HB: Lifespan Extension and Cellular Senescence Delay.

An, Yongpan; Wang, Qian; Qiao, Panshuang et al. · 2025 · Nutrients · DOI

Full title: Unveiling the Anti-Aging Potential of 3HB: Lifespan Extension and Cellular Senescence Delay.

Authors: An, Yongpan; Wang, Qian; Qiao, Panshuang; Liu, Jihan; Ma, Ang; Chen, Yutong; Yang, Daqian; Ying, Yi; Li, Nannan; Lu, Feng; Zhang, Hang; Chen, Guoqiang; Zhu, Yinhua; Yang, Baoxue; Xie, Zhengwei

Year: 2025

Venue: Nutrients

DOI: https://doi.org/10.3390/nu17101647

Paper Cellular Senescence in Health, Disease, and Lens Aging.

Qin, Ying; Liu, Haoxin; Wu, Hongli · 2025 · Pharmaceuticals (Basel, Switzerland) · DOI

Full title: Cellular Senescence in Health, Disease, and Lens Aging.

Authors: Qin, Ying; Liu, Haoxin; Wu, Hongli

Year: 2025

Venue: Pharmaceuticals (Basel, Switzerland)

DOI: https://doi.org/10.3390/ph18020244

Paper Researching New Drug Combinations with Senolytic Activity Using Senescent Human Lung Fibroblasts MRC-5 Cell Line

Maria Carolina Ximenes de Godoy; Juliana Alves Macedo; Alessandra Gambero · 2024 · Pharmaceuticals · DOI

Full title: Researching New Drug Combinations with Senolytic Activity Using Senescent Human Lung Fibroblasts MRC-5 Cell Line

Authors: Maria Carolina Ximenes de Godoy; Juliana Alves Macedo; Alessandra Gambero

Year: 2024

Venue: Pharmaceuticals

DOI: https://doi.org/10.3390/ph17010070

Paper Senolytics and Dietary Phytochemicals: Exploring Anti-Aging Strategies and Mechanisms in Aging and Disease

Edwin Dias; Darshak D Poojary · 2024 · International Journal For Multidisciplinary Research · DOI

Full title: Senolytics and Dietary Phytochemicals: Exploring Anti-Aging Strategies and Mechanisms in Aging and Disease

Authors: Edwin Dias; Darshak D Poojary

Year: 2024

Venue: International Journal For Multidisciplinary Research

Paper Determinants of human longevity: input of environment, nutrition, physical activity, eustress, heredity, health care, motivation, and mental state

Renad I. Zhdanov; R. Khayrullin; R. Khalilov et al. · 2023 · Exploration of Medicine · DOI

Full title: Determinants of human longevity: input of environment, nutrition, physical activity, eustress, heredity, health care, motivation, and mental state

Authors: Renad I. Zhdanov; R. Khayrullin; R. Khalilov; A. Eftekhari; Aleksey S. Sozinov

Year: 2023

Venue: Exploration of Medicine

DOI: https://doi.org/10.37349/emed.2023.00176

Paper Histone modification and anti-aging intervention

Rui Wang; Ting Li; Na Yang · 2025 · Scientia Sinica Vitae · DOI

Full title: Histone modification and anti-aging intervention

Authors: Rui Wang; Ting Li; Na Yang

Year: 2025

Venue: Scientia Sinica Vitae

DOI: https://doi.org/10.1360/ssv-2025-0106

Paper Cross-species functional modules link proteostasis to human normal aging.

Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo et al. · 2019 · PLoS computational biology · DOI

Full title: Cross-species functional modules link proteostasis to human normal aging.

Authors: Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo; Kutalik, Zoltán; Auwerx, Johan; Robinson-Rechavi, Marc

Year: 2019

Venue: PLoS computational biology

Paper Novel feature selection methods for construction of accurate epigenetic clocks.

Li, Adam; Mueller, Amber; English, Brad et al. · 2022 · PLoS computational biology · DOI

Full title: Novel feature selection methods for construction of accurate epigenetic clocks.

Authors: Li, Adam; Mueller, Amber; English, Brad; Arena, Anthony; Vera, Daniel; Kane, Alice E; Sinclair, David A

Year: 2022

Venue: PLoS computational biology

Paper Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

Dal‐Pan, Alexandre; Pifferi, Fabien; Marchal, Julia et al. · 2011 · PLoS ONE · DOI

Full title: Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

Authors: Dal‐Pan, Alexandre; Pifferi, Fabien; Marchal, Julia; Picq, Jean‐Luc; Aujard, Fabienne

Year: 2011

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0016581

Paper Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes

Wuttke, Daniel; Connor, Richard A.; Vora, Chintan et al. · 2012 · PLoS Genetics · DOI

Full title: Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes

Authors: Wuttke, Daniel; Connor, Richard A.; Vora, Chintan; Craig, Thomas; Li, Yang; Wood, Shona H.; Vasieva, Olga; Reis, Robert J. Shmookler; Tang, Fusheng; Magalhães, João Pedro de

Year: 2012

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1002834

Paper Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

Kiran Chaudhari; Jianmei Wang; Yong Xu et al. · 2020 · PLoS ONE · DOI

Full title: Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

Authors: Kiran Chaudhari; Jianmei Wang; Yong Xu; Ali Winters; Linshu Wang; Xiaowei Dong; Eric Y Cheng; Ran Liu; Shao-Hua Yang

Year: 2020

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0234571

Paper SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2

Zainabadi, Kayvan; Liu, Cassie J.; Guarente, Leonard · 2017 · PLoS ONE · DOI

Full title: SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2

Authors: Zainabadi, Kayvan; Liu, Cassie J.; Guarente, Leonard

Year: 2017

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0178520

Paper Stress Resistance and Longevity Are Not Directly Linked to Levels of Enzymatic Antioxidants in the Ponerine Ant Harpegnathos saltator

Schneider, Sebastian; Schrader, Charlotte; Wagner, Anika E. et al. · 2011 · PLoS ONE · DOI

Full title: Stress Resistance and Longevity Are Not Directly Linked to Levels of Enzymatic Antioxidants in the Ponerine Ant Harpegnathos saltator

Authors: Schneider, Sebastian; Schrader, Charlotte; Wagner, Anika E.; Boesch‐Saadatmandi, Christine; Liebig, Jüergen; Rimbach, Gerald; Roeder, Thomas

Year: 2011

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0014601

Paper The spatial association of gene expression evolves from synchrony to asynchrony and stochasticity with age.

Wang, Qi; Huang, Jianhua; Zhang, Xinmin et al. · 2011 · PloS one · DOI

Full title: The spatial association of gene expression evolves from synchrony to asynchrony and stochasticity with age.

Authors: Wang, Qi; Huang, Jianhua; Zhang, Xinmin; Wu, Bin; Liu, Xiaoyu; Shen, Ziyin

Year: 2011

Venue: PloS one

DOI: https://doi.org/10.1371/journal.pone.0024076

Paper Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice

N. Thangthaeng; Margaret Rutledge; Jessica M. Wong et al. · 2017 · Aging and Disease · DOI

Full title: Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice

Authors: N. Thangthaeng; Margaret Rutledge; Jessica M. Wong; Philip H. Vann; M. Forster; N. Sumien

Year: 2017

Venue: Aging and Disease

DOI: https://doi.org/10.14336/ad.2016.1010

Paper Geroprotectors: A Unified Concept and Screening Approaches.

Moskalev, Alexey; Chernyagina, Elizaveta; Kudryavtseva, Anna et al. · 2017 · Aging and disease · DOI

Full title: Geroprotectors: A Unified Concept and Screening Approaches.

Authors: Moskalev, Alexey; Chernyagina, Elizaveta; Kudryavtseva, Anna; Shaposhnikov, Mikhail

Year: 2017

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2016.1022

Paper Stop Aging Disease! ICAD 2014.

Stambler, Ilia · 2015 · Aging and disease · DOI

Full title: Stop Aging Disease! ICAD 2014.

Authors: Stambler, Ilia

Year: 2015

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2015.0115

Paper Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Liebich, Alina; Zheng, Shenglin; Schachner, Theresa et al. · 2024 · PLoS ONE · DOI

Full title: Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Authors: Liebich, Alina; Zheng, Shenglin; Schachner, Theresa; Mair, Jacqueline L.; Jovanova, Mia; Müller‐Riemenschneider, Falk; Kowatsch, Tobias

Year: 2024

Venue: PLoS ONE

DOI: https://doi.org/10.1371/journal.pone.0301763

Paper Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging

Rahman, Sajid Ur; Qadeer, Abdul; Wu, Ziyun · 2023 · Aging and Disease · DOI

Full title: Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging

Authors: Rahman, Sajid Ur; Qadeer, Abdul; Wu, Ziyun

Year: 2023

Venue: Aging and Disease

DOI: https://doi.org/10.14336/ad.2023.0519-1

Paper Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience.

Moskalev, Alexey; Stambler, Ilia; Caruso, Calogero · 2020 · Aging and disease · DOI

Full title: Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience.

Authors: Moskalev, Alexey; Stambler, Ilia; Caruso, Calogero

Year: 2020

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2020.0603

Paper Geroscience in the Age of COVID-19.

Barzilai, Nir; Appleby, James C; Austad, Steven N et al. · 2020 · Aging and disease · DOI

Full title: Geroscience in the Age of COVID-19.

Authors: Barzilai, Nir; Appleby, James C; Austad, Steven N; Cuervo, Ana Maria; Kaeberlein, Matt; Gonzalez-Billault, Christian; Lederman, Stephanie; Stambler, Ilia; Sierra, Felipe

Year: 2020

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2020.0629

Paper Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions.

Chmielewski, Piotr Paweł; Data, Krzysztof; Strzelec, Bartłomiej et al. · 2024 · Aging and disease · DOI

Full title: Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions.

Authors: Chmielewski, Piotr Paweł; Data, Krzysztof; Strzelec, Bartłomiej; Farzaneh, Maryam; Anbiyaiee, Amir; Zaheer, Uzma; Uddin, Shahab; Sheykhi-Sabzehpoush, Mohadeseh; Mozdziak, Paul; Zabel, Maciej; Dzięgiel, Piotr; Kempisty, Bartosz

Year: 2024

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2024.0280

Paper Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Irie, Junichiro; Inagaki, Emi; Fujita, Masataka et al. · 2019 · Endocrine Journal · DOI

Full title: Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Authors: Irie, Junichiro; Inagaki, Emi; Fujita, Masataka; Nakaya, Hideaki; Mitsuishi, Masanori; Yamaguchi, Shintaro; Yamashita, Kazuya; Shigaki, Shuhei; Ono, Takashi; Yukioka, Hideo; Okano, Hideyuki; Nabeshima, Yo-ichi; Imai, Shin‐ichiro; Yasui, Masato; Tsubota, Kazuo; Itoh, Hiroshi

Year: 2019

Venue: Endocrine Journal

DOI: https://doi.org/10.1507/endocrj.ej19-0313

Paper An age classification model based on DNA methylation biomarkers of aging inhuman peripheral blood using random forest and artificial neural network

Li, Ye; Yang, Yukun; He, Jie et al. · 2024 · Cellular and Molecular Biology · DOI

Full title: An age classification model based on DNA methylation biomarkers of aging inhuman peripheral blood using random forest and artificial neural network

Authors: Li, Ye; Yang, Yukun; He, Jie; Hu, Jinxiu; Zhu, Xiangqing; Tian, Chuan; Chen, Mengdie; Xiao-juan, Zhao; Li, Ye; Pan, Hang; Pan, Xinghua

Year: 2024

Venue: Cellular and Molecular Biology

DOI: https://doi.org/10.14715/cmb/2024.70.1.21

Paper Loss of Nat4 and its associated histone H4 N‐terminal acetylation mediates calorie restriction‐induced longevity

Molina‐Serrano, Diego; Schiza, Vassia; Demosthenous, Christis et al. · 2016 · EMBO Reports · DOI

Full title: Loss of Nat4 and its associated histone H4 N‐terminal acetylation mediates calorie restriction‐induced longevity

Authors: Molina‐Serrano, Diego; Schiza, Vassia; Demosthenous, Christis; Stavrou, Emmanouil; Oppelt, Jan; Kyriakou, Dimitris; Liu, Wei; Zisser, Gertrude; Bergler, Helmut; Dang, Weiwei; Kirmizis, Antonis

Year: 2016

Venue: EMBO Reports

DOI: https://doi.org/10.15252/embr.201642540

Paper Targeting GATA transcription factors - a novel strategy for anti-aging interventions?

Zimmermann, Andreas; Kainz, Katharina; Hofer, Sebastian J et al. · 2019 · Microbial cell (Graz, Austria) · DOI

Full title: Targeting GATA transcription factors - a novel strategy for anti-aging interventions?

Authors: Zimmermann, Andreas; Kainz, Katharina; Hofer, Sebastian J; Bauer, Maria A; Schroeder, Sabrina; Dengjel, Jörn; Pietrocola, Federico; Kepp, Oliver; Ruckenstuhl, Christoph; Eisenberg, Tobias; Sigrist, Stephan J; Madeo, Frank; Kroemer, Guido; Carmona-Gutierrez, Didac

Year: 2019

Venue: Microbial cell (Graz, Austria)

DOI: https://doi.org/10.15698/mic2019.05.676

Paper When less is more: hormesis against stress and disease

Zimmermann, Andreas; Bauer, Maria A.; Kroemer, Guido et al. · 2014 · Microbial Cell · DOI

Full title: When less is more: hormesis against stress and disease

Authors: Zimmermann, Andreas; Bauer, Maria A.; Kroemer, Guido; Madeo, Frank; Carmona‐Gutiérrez, Didac; France., Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Pavillon de Recherche 1, 94805 Villejuif,; France., Pole de Biologie, Hopital Europeen Georges Pompidou, AP-HP, 20 Rue Leblanc, 75015 Paris,

Year: 2014

Venue: Microbial Cell

DOI: https://doi.org/10.15698/mic2014.05.148

Paper Healthy human aging: intrinsic and environmental factors

Sgarbieri, Valdemiro Carlos; Pacheco, Maria Teresa Bertoldo · 2017 · Brazilian journal of food technology/Brazilian Journal of Food Technology · DOI

Full title: Healthy human aging: intrinsic and environmental factors

Authors: Sgarbieri, Valdemiro Carlos; Pacheco, Maria Teresa Bertoldo

Year: 2017

Venue: Brazilian journal of food technology/Brazilian Journal of Food Technology

DOI: https://doi.org/10.1590/1981-6723.00717

Paper Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions.

Mousa, Shaker A; Gallati, Christine; Simone, Tessa et al. · 2009 · Aging · DOI

Full title: Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions.

Authors: Mousa, Shaker A; Gallati, Christine; Simone, Tessa; Dier, Emmy; Yalcin, Murat; Dyskin, Evgeny; Thangirala, Sudha; Hanko, Christine; Rebbaa, Abdelhadi

Year: 2009

Venue: Aging

DOI: https://doi.org/10.18632/aging.100035

Paper Long-term rapamycin treatment suppresses IL-17-producing gamma delta T cells and blunts neuroinflammation in aging

Clement Torrent; Caterina Gagliardi; Nina Fülle et al. · 2026 · bioRxiv · DOI

Full title: Long-term rapamycin treatment suppresses IL-17-producing gamma delta T cells and blunts neuroinflammation in aging

Authors: Clement Torrent; Caterina Gagliardi; Nina Fülle; Ignazio Antignano; M. E. Bernis; Miriam Stork; Daniele Bano; Melania Capasso; Lily Keane

Year: 2026

Venue: bioRxiv

DOI: https://doi.org/10.64898/2026.02.04.703808

Paper Synergistic pharmacological interventions and lifestyle modifications to decelerate aging: Targeting cellular senescence and metabolic pathways for longevity

Middha, Sushil Kumar; Mathur, Shivangi; Singh, Kavita et al. · 2025 · DOI

Full title: Synergistic pharmacological interventions and lifestyle modifications to decelerate aging: Targeting cellular senescence and metabolic pathways for longevity

Authors: Middha, Sushil Kumar; Mathur, Shivangi; Singh, Kavita; Kumar, Avnish; Kantwa, Sanwar Mal; Paital, Biswaranjan; Usha, Talambedu

Year: 2025

DOI: https://doi.org/10.70593/978-93-49910-64-5_9

Paper Unexpected Increase in Bone Mineral Density With Rapamycin and Low-Dose Naltrexone: A Case Report of a 52-Year-Old Woman With Osteopenia

Britton, Annie; Harinath, Girish; Morgan, Sarah L. et al. · 2025 · Cureus · DOI

Full title: Unexpected Increase in Bone Mineral Density With Rapamycin and Low-Dose Naltrexone: A Case Report of a 52-Year-Old Woman With Osteopenia

Authors: Britton, Annie; Harinath, Girish; Morgan, Sarah L.; Zalzala, Sajad

Year: 2025

Venue: Cureus

DOI: https://doi.org/10.7759/cureus.77435

Paper Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems

A. Tammaro; Eileen G. Daniels; I. M. Hu et al. · 2023 · bioRxiv · DOI

Full title: Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems

Authors: A. Tammaro; Eileen G. Daniels; I. M. Hu; Kelly C. ‘t Hart; K. Reid; R. Juni; L. Butter; G. Vasam; Rashmi Kamble; A. Jongejan; Richard I. Aviv; J. Roelofs; E. Aronica; R. Boon; Keir J. Menzies; R. Houtkooper; G. Janssens

Year: 2023

Venue: bioRxiv

DOI: https://doi.org/10.1101/2023.08.29.555280

Paper Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

Andrea Di Francesco; Andrew Deighan; L. Litichevskiy et al. · 2023 · bioRxiv · DOI

Full title: Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

Authors: Andrea Di Francesco; Andrew Deighan; L. Litichevskiy; Zhenghao Chen; Alison Luciano; Laura Robinson; Gaven Garland; Hannah Donato; Will Schott; Kevin M. Wright; Anil Raj; G. Prateek; Martin N. Mullis; Warren Hill; Mark L Zeidel; Luanne L Peters; Fiona Harding; D. Botstein; R. Korstanje; Christoph A. Thaiss; Adam Freund; G. Churchill

Year: 2023

Venue: bioRxiv

DOI: https://doi.org/10.1101/2023.11.28.568901

Paper Current Research On Epigenetic Age and Cellular Senescence: A Bibliometric and Visual Analysis

Kahaer, Mayina; Hao, Baoshun; Sun, M.M Zhi-Guo et al. · 2024 · DOI

Full title: Current Research On Epigenetic Age and Cellular Senescence: A Bibliometric and Visual Analysis

Authors: Kahaer, Mayina; Hao, Baoshun; Sun, M.M Zhi-Guo; Xu, M.M Kuo; Aikeremu, M.M Dilimulati

Year: 2024

DOI: https://doi.org/10.1101/2024.02.13.580124

Paper Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies

Jiang, Nisi; Cheng, Catherine; Liu, Qianqian et al. · 2024 · DOI

Full title: Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies

Authors: Jiang, Nisi; Cheng, Catherine; Liu, Qianqian; Strong, Randy; Gelfond, Jonathan; Nelson, James F.

Year: 2024

DOI: https://doi.org/10.1101/2024.03.27.585737

Paper Organ specificity and commonality of epigenetic aging in low- and high-running capacity rats

Kawamura, Takuji; Kerepesi, Csaba; Torma, Ferenc et al. · 2024 · DOI

Full title: Organ specificity and commonality of epigenetic aging in low- and high-running capacity rats

Authors: Kawamura, Takuji; Kerepesi, Csaba; Torma, Ferenc; Bori, Zoltán; Zhou, Lei; Bakonyi, Péter; Kolonics, Attila; Balogh, László; Higuchi, Mitsuru; Koch, Lauren G.; Britton, Steven L.; Koltai, Erika; Radák, Zsolt

Year: 2024

DOI: https://doi.org/10.1101/2024.04.21.590009

Paper Differential Responses of Dynamic and Entropic Aging Factors to Longevity Interventions

Kristina Perevoshchikova; P. Fedichev · 2024 · bioRxiv · DOI

Full title: Differential Responses of Dynamic and Entropic Aging Factors to Longevity Interventions

Authors: Kristina Perevoshchikova; P. Fedichev

Year: 2024

Venue: bioRxiv

DOI: https://doi.org/10.1101/2024.02.25.581928

Paper Functional and multi-omic aging rejuvenation with GLP-1R agonism

Junzhe Huang; Andrew J Kwok; Jason Chak Yan Li et al. · 2024 · bioRxiv · DOI

Full title: Functional and multi-omic aging rejuvenation with GLP-1R agonism

Authors: Junzhe Huang; Andrew J Kwok; Jason Chak Yan Li; Clement Lek Hin Chiu; B. Ip; Lok Yi Tung; Xianyi Zheng; Hoi Tung Chow; Michelle P. S. Lo; Zhongqi Li; Roy C. H. Chan; Nenghan Lin; Ziyu Wang; Manyu Wang; Leo Y. C. Yan; Danny C. W. Chan; W. K. K. Wu; Kim Hei-Man Chow; Wei-jye Lin; Yamei Tang; Billy Wai-Lung Ng; S. Wong; T. W. Leung; Vincent C. T. Mok; Ho Ko

Year: 2024

Venue: bioRxiv

DOI: https://doi.org/10.1101/2024.05.06.592653

Paper DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans

Raghav Sehgal; D. Borrus; Jessica Kasamato et al. · 2024 · bioRxiv · DOI

Full title: DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans

Authors: Raghav Sehgal; D. Borrus; Jessica Kasamato; Jenel F. Armstrong; John T. González; Yaroslav Markov; Ahana Priyanka; Ryan Smith; Natàlia Carreras; Varun B. Dwaraka; A. Higgins-Chen

Year: 2024

Venue: bioRxiv

DOI: https://doi.org/10.1101/2024.10.22.619522

Paper Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

Al-Saadi, Rose S; Phillips, Patrick C · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

Authors: Al-Saadi, Rose S; Phillips, Patrick C

Year: 2025

Venue: bioRxiv : the preprint server for biology

Paper An Open Competition for Biomarkers of Aging.

Ying, Kejun; Paulson, Seth; Reinhard, Julian et al. · 2024 · bioRxiv : the preprint server for biology · DOI

Full title: An Open Competition for Biomarkers of Aging.

Authors: Ying, Kejun; Paulson, Seth; Reinhard, Julian; de Lima Camillo, Lucas Paulo; Träuble, Jakob; Jokiel, Stefan; Biomarkers of Aging Consortium; Gobel, Dane; Herzog, Chiara; Poganik, Jesse R; Moqri, Mahdi; Gladyshev, Vadim N

Year: 2024

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2024.10.29.620782

Paper High-dimensional Ageome Representations of Biological Aging across Functional Modules

Kejun Ying; A. Tyshkovskiy; Qingwen Chen et al. · 2024 · bioRxiv · DOI

Full title: High-dimensional Ageome Representations of Biological Aging across Functional Modules

Authors: Kejun Ying; A. Tyshkovskiy; Qingwen Chen; Eric Latorre-Crespo; Bohan Zhang; Hanna Liu; Benyamin Matei-Dediu; J. Poganik; M. Moqri; Kristina Kirschne; J. Lasky-Su; Vadim N. Gladyshev

Year: 2024

Venue: bioRxiv

DOI: https://doi.org/10.1101/2024.09.17.613599

Paper Tissue-specific modulation of NADH consumption as an anti-aging intervention in Drosophila

S. Yadav; Xingxiu Pan; Shengxi Li et al. · 2025 · bioRxiv · DOI

Full title: Tissue-specific modulation of NADH consumption as an anti-aging intervention in Drosophila

Authors: S. Yadav; Xingxiu Pan; Shengxi Li; Paige LaRae Martin; Ngoc Hoang; Kejin Chen; Aditi Karhadkar; Jatin Malhotra; Austin L. Zuckerman; Subrata Munan; Markus K. Klose; Lin Wang; Valentin Cracan; Andrey A. Parkhitko

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.01.06.631511

Paper Spatiotemporal profiling reveals the impact of caloric restriction on mammalian brain aging.

Zhang, Zehao; Epstein, Alexander; Schaefer, Chloe et al. · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: Spatiotemporal profiling reveals the impact of caloric restriction on mammalian brain aging.

Authors: Zhang, Zehao; Epstein, Alexander; Schaefer, Chloe; Abdulraouf, Abdulraouf; Jiang, Weirong; Zhou, Wei; Cao, Junyue

Year: 2025

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2025.05.04.652093

Paper SRS microscopy identifies inhibition of vitellogenesis as a mediator of lifespan extension by caloric restriction in C. elegans

Bowen Yang; Bryce Manifold; Wuji Han et al. · 2025 · bioRxiv · DOI

Full title: SRS microscopy identifies inhibition of vitellogenesis as a mediator of lifespan extension by caloric restriction in C. elegans

Authors: Bowen Yang; Bryce Manifold; Wuji Han; Catherin DeSousa; Wanyi Zhu; Aaron Streets; Denis V. Titov

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.01.31.636008

Paper Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database.

Parish, Austin; Ioannidis, John P A; Zhang, Kevin et al. · 2025 · npj aging · DOI

Full title: Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database.

Authors: Parish, Austin; Ioannidis, John P A; Zhang, Kevin; Barardo, Diogo; R Swindell, William; de Magalhães, João Pedro

Year: 2025

Venue: npj aging

Paper Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

Aaron P. Havas; Adarsh Rajesh; Xue Lei et al. · 2025 · bioRxiv · DOI

Full title: Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

Authors: Aaron P. Havas; Adarsh Rajesh; Xue Lei; Jessica Proulx; Karl N. Miller; Adam Field; Andrew Davis; M. Teneche; Armin Gandhi; P. Adams

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.07.25.666837

Paper A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

Jialiang Yang; Bin Zhang; S. Houten et al. · 2018 · bioRxiv · DOI

Full title: A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

Authors: Jialiang Yang; Bin Zhang; S. Houten; E. Schadt; Jun Zhu; Y. Suh; Zhidong Tu

Year: 2018

Venue: bioRxiv

DOI: https://doi.org/10.1101/326264

Paper scAgeClock: a single-cell transcriptome based human aging clock model using gated multi-head attention neural networks

Gangcai Xie · 2025 · bioRxiv · DOI

Full title: scAgeClock: a single-cell transcriptome based human aging clock model using gated multi-head attention neural networks

Authors: Gangcai Xie

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.08.29.673183

Paper Identification of key pathways and metabolic fingerprints of longevity in C. elegans

Gao, Arwen W.; Smith, Reuben L.; Weeghel, Michel van et al. · 2017 · DOI

Full title: Identification of key pathways and metabolic fingerprints of longevity in C. elegans

Authors: Gao, Arwen W.; Smith, Reuben L.; Weeghel, Michel van; Kamble, Rashmi; Houtkooper, Riekelt H.

Year: 2017

DOI: https://doi.org/10.1101/222554

Paper Machine learning based classification of cells into chronological stages using single-cell transcriptomics

Singh, Sumeet Pal; Janjuha, Sharan; Chaudhuri, Samata et al. · 2018 · DOI

Full title: Machine learning based classification of cells into chronological stages using single-cell transcriptomics

Authors: Singh, Sumeet Pal; Janjuha, Sharan; Chaudhuri, Samata; Reinhardt, Susanne; Dietz, Sevina; Eugster, Anne; Bilgin, Halil; Korkmaz, Selçuk; Reid, John E.; Zararsız, Gökmen; Ninov, Nikolay

Year: 2018

DOI: https://doi.org/10.1101/303214

Paper Epigenetic Age-Predictor for Mice based on Three CpG Sites

Han, Yang; Eipel, Monika; Sakk, Vadim et al. · 2018 · DOI

Full title: Epigenetic Age-Predictor for Mice based on Three CpG Sites

Authors: Han, Yang; Eipel, Monika; Sakk, Vadim; Dethmers-Ausema, Bertien; Haan, Gerald de; Geiger, Hartmut; Wagner, Wolfgang

Year: 2018

DOI: https://doi.org/10.1101/296525

Paper Tolerance to NADH/NAD + imbalance anticipates aging and anti-aging interventions

Alonso-Lavin, Alvar J.; Bajić, Djordje; Poyatos, Juan F. · 2019 · DOI

Full title: Tolerance to NADH/NAD + imbalance anticipates aging and anti-aging interventions

Authors: Alonso-Lavin, Alvar J.; Bajić, Djordje; Poyatos, Juan F.

Year: 2019

DOI: https://doi.org/10.1101/719401

Paper Automated Lifespan Determination Across Caenorhabditis Strains and Species Reveals Assay-Specific Effects of Chemical Interventions

Banse, Stephen A.; Lucanic, Mark; Sedore, Christine A. et al. · 2019 · DOI

Full title: Automated Lifespan Determination Across Caenorhabditis Strains and Species Reveals Assay-Specific Effects of Chemical Interventions

Authors: Banse, Stephen A.; Lucanic, Mark; Sedore, Christine A.; Coleman-Hulbert, Anna L; Plummer, W. Todd; Chen, Esteban; Kish, Jason L.; Hall, David J.; Onken, Brian; Presley, Michael P.; Jones, E Grace; Blue, Benjamin W.; Garrett, Theo; Abbott, Mark B.; Xue, Jian; Guo, Suzhen; Johnson, Erik; Foulger, Anna; Chamoli, Manish; Falkowski, Ron; Melentijevic, Ilija; Harinath, Girish; Huynh, Phu; Patel, Shobhna; Edgar, Daniel; Jarrett, Cody M.; Guo, Max; Kapahi, Pankaj; Lithgow, Gordon J.; Driscoll, Monica; Phillips, Patrick C.

Year: 2019

DOI: https://doi.org/10.1101/757302

Paper Cross-species functional modules link proteostasis to human normal aging.

Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo et al. · 2019 · PLoS computational biology · DOI

Full title: Cross-species functional modules link proteostasis to human normal aging.

Authors: Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo; Kutalik, Zoltán; Auwerx, Johan; Robinson-Rechavi, Marc

Year: 2019

Venue: PLoS computational biology

Paper Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans

Zhang, Yue; Lanjuin, Anne; Chowdhury, Suvagata Roy et al. · 2019 · DOI

Full title: Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans

Authors: Zhang, Yue; Lanjuin, Anne; Chowdhury, Suvagata Roy; Mistry, Meeta; Silva-García, Carlos G.; Weir, Heather J.; Lee, Chia-Lin; Escoubas, Caroline C.; Tabakovic, Emina; Mair, William B.

Year: 2019

DOI: https://doi.org/10.1101/665190

Paper A CellAgeClock for expedited discovery of anti-ageing compounds

C. Lujan; E. Tyler; A. Webster et al. · 2019 · DOI

Full title: A CellAgeClock for expedited discovery of anti-ageing compounds

Authors: C. Lujan; E. Tyler; A. Webster; E. Stead; V. E. M. Miguel; Simone Ecker; Deborah A. Milligan; J. Garbe; M. Stampfer; S. Beck; R. Lowe; C. Bishop; I. Bjedov

Year: 2019

DOI: https://doi.org/10.1101/803676

Paper Quantitative translation of dog-to-human aging by conserved remodeling of epigenetic networks

Tina Wang; Jianzhu Ma; A. Hogan et al. · 2019 · bioRxiv · DOI

Full title: Quantitative translation of dog-to-human aging by conserved remodeling of epigenetic networks

Authors: Tina Wang; Jianzhu Ma; A. Hogan; Samson H. Fong; Katherine Licon; B. Tsui; J. Kreisberg; P. Adams; Anne-Ruxandra Carvunis; D. Bannasch; E. Ostrander; T. Ideker

Year: 2019

Venue: bioRxiv

DOI: https://doi.org/10.1101/829192

Paper Inhibition of the Mechanistic Target of Rapamycin (mTOR)–Rapamycin and Beyond

Lamming, Dudley W. · 2016 · Cold Spring Harbor Perspectives in Medicine · DOI

Full title: Inhibition of the Mechanistic Target of Rapamycin (mTOR)–Rapamycin and Beyond

Authors: Lamming, Dudley W.

Year: 2016

Venue: Cold Spring Harbor Perspectives in Medicine

DOI: https://doi.org/10.1101/cshperspect.a025924

Paper The Aging Heart: Figure 1.

Chiao, Ying Ann; Rabinovitch, Peter S. · 2015 · Cold Spring Harbor Perspectives in Medicine · DOI

Full title: The Aging Heart: Figure 1.

Authors: Chiao, Ying Ann; Rabinovitch, Peter S.

Year: 2015

Venue: Cold Spring Harbor Perspectives in Medicine

DOI: https://doi.org/10.1101/cshperspect.a025148

Paper Metformin: A Hopeful Promise in Aging Research.

M. G. Novelle; A. Ali; C. Diéguez et al. · 2016 · Cold Spring Harbor Perspectives in Medicine · DOI

Full title: Metformin: A Hopeful Promise in Aging Research.

Authors: M. G. Novelle; A. Ali; C. Diéguez; M. Bernier; R. de Cabo

Year: 2016

Venue: Cold Spring Harbor Perspectives in Medicine

DOI: https://doi.org/10.1101/cshperspect.a025932

Paper A transcriptome-based single-cell biological age model and resource for tissue-specific aging measures

Mao, Shulin; Su, Jiayu; Wang, Longteng et al. · 2023 · Genome Research · DOI

Full title: A transcriptome-based single-cell biological age model and resource for tissue-specific aging measures

Authors: Mao, Shulin; Su, Jiayu; Wang, Longteng; Bo, Xiaochen; Li, Cheng; Chen, Hebing

Year: 2023

Venue: Genome Research

DOI: https://doi.org/10.1101/gr.277491.122

Paper Immune Memory in Aging: a Wide Perspective Covering Microbiota, Brain, Metabolism, and Epigenetics.

Bulut, Ozlem; Kilic, Gizem; Domínguez-Andrés, Jorge · 2022 · Clinical reviews in allergy & immunology · DOI

Full title: Immune Memory in Aging: a Wide Perspective Covering Microbiota, Brain, Metabolism, and Epigenetics.

Authors: Bulut, Ozlem; Kilic, Gizem; Domínguez-Andrés, Jorge

Year: 2022

Venue: Clinical reviews in allergy & immunology

DOI: https://doi.org/10.1007/s12016-021-08905-x

Paper Antiaging agents: safe interventions to slow aging and healthy life span extension

Liu, Ji‐Kai · 2022 · Natural Products and Bioprospecting · DOI

Full title: Antiaging agents: safe interventions to slow aging and healthy life span extension

Authors: Liu, Ji‐Kai

Year: 2022

Venue: Natural Products and Bioprospecting

DOI: https://doi.org/10.1007/s13659-022-00339-y

Paper Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Zhu, Xudong; Chen, Zhiyang; Shen, Weiyan et al. · 2021 · Signal Transduction and Targeted Therapy · DOI

Full title: Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Authors: Zhu, Xudong; Chen, Zhiyang; Shen, Weiyan; Huang, Gang; Sedivy, John M.; Wang, Hu; Ju, Zhenyu

Year: 2021

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-021-00646-9

Paper Inflammation and aging: signaling pathways and intervention therapies

Li, Xia; Li, Chentao; Zhang, Wanying et al. · 2023 · Signal Transduction and Targeted Therapy · DOI

Full title: Inflammation and aging: signaling pathways and intervention therapies

Authors: Li, Xia; Li, Chentao; Zhang, Wanying; Wang, Yanan; Qian, Pengxu; Huang, He

Year: 2023

Venue: Signal Transduction and Targeted Therapy

DOI: https://doi.org/10.1038/s41392-023-01502-8

Paper Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

Xie, Kan; Fuchs, Helmut; Scifo, Enzo et al. · 2022 · Nature communications · DOI

Full title: Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

Authors: Xie, Kan; Fuchs, Helmut; Scifo, Enzo; Liu, Dan; Aziz, Ahmad; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Cho, Yi-Li; Deng, Yushuang; Edwards, A Cole; Garrett, Lillian; Georgopoulou, Christina; Gerlini, Raffaele; Hölter, Sabine M; Klein-Rodewald, Tanja; Kramer, Michael; Leuchtenberger, Stefanie; Lountzi, Dimitra; Mayer-Kuckuk, Phillip; Nover, Lena L; Oestereicher, Manuela A; Overkott, Clemens; Pearson, Brandon L; Rathkolb, Birgit; Rozman, Jan; Russ, Jenny; Schaaf, Kristina; Spielmann, Nadine; Sanz-Moreno, Adrián; Stoeger, Claudia; Treise, Irina; Bano, Daniele; Busch, Dirk H; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Mock, Beverly A; Salomoni, Paolo; Schmidt-Weber, Carsten; Weiergräber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valérie; Breteler, Monique M B; Hrabě de Angelis, Martin; Ehninger, Dan

Year: 2022

Venue: Nature communications

Paper Emerging insights in senescence: pathways from preclinical models to therapeutic innovations

L. Mansfield; Valentina Ramponi; Kavya Gupta et al. · 2024 · npj Aging · DOI

Full title: Emerging insights in senescence: pathways from preclinical models to therapeutic innovations

Authors: L. Mansfield; Valentina Ramponi; Kavya Gupta; Thomas Stevenson; Abraham B Mathew; A. J. Barinda; Florencia Herbstein; Samir Morsli

Year: 2024

Venue: npj Aging

DOI: https://doi.org/10.1038/s41514-024-00181-1

Paper Decoding senescence of aging single cells at the nexus of biomaterials, microfluidics, and spatial omics.

Venkataraman, Abhijeet; Kordic, Ivan; Li, JiaXun et al. · 2024 · npj aging · DOI

Full title: Decoding senescence of aging single cells at the nexus of biomaterials, microfluidics, and spatial omics.

Authors: Venkataraman, Abhijeet; Kordic, Ivan; Li, JiaXun; Zhang, Nicholas; Bharadwaj, Nivik Sanjay; Fang, Zhou; Das, Sandip; Coskun, Ahmet F

Year: 2024

Venue: npj aging

DOI: https://doi.org/10.1038/s41514-024-00178-w

Paper Modeling transcriptomic age using knowledge-primed artificial neural networks.

Holzscheck, Nicholas; Falckenhayn, Cassandra; Söhle, Jörn et al. · 2021 · NPJ aging and mechanisms of disease · DOI

Full title: Modeling transcriptomic age using knowledge-primed artificial neural networks.

Authors: Holzscheck, Nicholas; Falckenhayn, Cassandra; Söhle, Jörn; Kristof, Boris; Siegner, Ralf; Werner, André; Schössow, Janka; Jürgens, Clemens; Völzke, Henry; Wenck, Horst; Winnefeld, Marc; Grönniger, Elke; Kaderali, Lars

Year: 2021

Venue: NPJ aging and mechanisms of disease

DOI: https://doi.org/10.1038/s41514-021-00068-5

Paper Universal DNA methylation age across mammalian tissues

Lu, Aimei; Fei, Zhe; Haghani, Amin et al. · 2021 · DOI

Full title: Universal DNA methylation age across mammalian tissues

Authors: Lu, Aimei; Fei, Zhe; Haghani, Amin; Robeck, Todd R.; Zoller, Joseph A.; Li, Chengzhang; Lowe, Robert; Yan, Qi; Zhang, Joshua; Vu, Hoang‐Giang; Ablaeva, Julia; Acosta-Rodríguez, Victoria A.; Adams, Denise M.; Almunia, Javier; Aloysius, Ajoy; Ardehali, Reza; Arneson, A; Baker, C. Scott; Banks, Gareth; Belov, Katherine; Bennett, Nigel C.; Black, Peter McL.; Blumstein, Daniel T.; Bors, Eleanor K.; Breeze, Charles E.; Brooke, Robert T.; Brown, Janine L.; Carter, G.; Caulton, Alex; Cavin, Julie M.; Chakrabarti, Lisa; Chatzistamou, Ioulia; Chen, Hao; Cheng, Kai; Chiavellini, Priscila; Choi, Oi‐Wa; Clarke, Shannon; Cooper, Lisa Noelle; Cossette, Marie‐Laurence; Day, Joanna; DeYoung, Joseph; DiRocco, Stacy; Dold, Christopher; Ehmke, Erin E.; Emmons, Candice K.; Emmrich, Stephan; Erbay, Ebru; Erlacher‐Reid, Claire; Faulkes, Christopher G.; Ferguson, Steven H.; Finno, Carrie J.; Flower, Jennifer E.; Gaillard, Jean‐Michel; Garde, Eva; Gerber, Livia; Gladyshev, Vadim N.; Gorbunova, Vera; Goya, Rodolfo G.; Grant, Maria J.; Green, C.B.; Hales, Erin N.; Hanson, M. Bradley; Hart, Daniel W.; Haulena, Martin; Herrick, K.; Hogan, Andrew N.; Hogg, Carolyn J.; Hore, T.A.; Huang, Taosheng; Belmonte, Juan Carlos Izpisúa; Jasinska, Anna J.; Jones, Gareth; Jourdain, Eve; Kashpur, Olga; Katcher, Harold L.; Katsumata, Etsuko; Kaza, Vimala; Kiaris, Hippokratis; Kobor, Michael S.; Kordowitzki, Paweł; Koski, William R.; Kruetzen, Michael; Kwon, Soon‐Bae; Larison, Brenda; Lee, Sang‐Goo; Lehmann, Marina; Lemaître, Jean‐François; Levine, Andrew J.; Li, Chengzhang; Li, X.; Lim, A.; Lin, David; Lindemann, D.; Little, Tom J.; Macoretta, Nicholas; Maddox, Debra; Matkin, Craig O.; Mattison, Julie A.; McClure, Mélanie; Mergl, June

Year: 2021

DOI: https://doi.org/10.1101/2021.01.18.426733

Paper TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Griffin, Patrick; Kane, Alice E.; Trapp, Alexandre et al. · 2021 · DOI

Full title: TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Authors: Griffin, Patrick; Kane, Alice E.; Trapp, Alexandre; Li, Jien; Arnold, Matthew; Poganik, Jesse R.; McNamara, Maeve S.; Meer, Margarita; Hoffman, Noah G.; Amorim, João Pedro; Tian, Xiao; MacArthur, Michael R.; Mitchell, Sarah J.; Mueller, Amber L.; Carmody, Colleen; Vera, Daniel L.; Kerepesi, Csaba; Hooten, Nicole Noren; Mitchell, James R.; Evans, Michele K.; Gladyshev, Vadim N.; Sinclair, David

Year: 2021

DOI: https://doi.org/10.1101/2021.10.25.465725

Paper The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

Suchacki, Karla J.; Thomas, Benjamin J.; Ikushima, Yoshiko Matsumoto et al. · 2022 · DOI

Full title: The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

Authors: Suchacki, Karla J.; Thomas, Benjamin J.; Ikushima, Yoshiko Matsumoto; Chen, Kuan-Chan; Fyfe, Claire; Tavares, Adriana; Sulston, Richard J.; Lovdel, Andrea; Woodward, Holly J.; Han, Xuan; Mattiucci, Domenico; Brain, Eleanor J; Alcaide‐Corral, Carlos J.; Kobayashi, Hiroshi; Gray, Gillian A.; Whitfield, Phillip D.; Stimson, Roland H.; Morton, Nicholas M.; Johnstone, Alexandra M.; Cawthorn, William P.

Year: 2022

DOI: https://doi.org/10.1101/2022.02.20.481222

Paper Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

Xie, Kan; Fuchs, Helmut; Scifo, Enzo et al. · 2022 · Nature communications · DOI

Full title: Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

Year: 2022

Venue: Nature communications

DOI: https://doi.org/10.3390/books978-3-03943-838-9

Paper Reduced insulin signalling in neurons induces sex-specific health benefits

Baghdadi, Maarouf; Nespital, Tobias; Mesaros, Andrea et al. · 2022 · DOI

Full title: Reduced insulin signalling in neurons induces sex-specific health benefits

Authors: Baghdadi, Maarouf; Nespital, Tobias; Mesaros, Andrea; Buschbaum, Sandra; Withers, Dominic J.; Grönke, Sebastian; Partridge, Linda

Year: 2022

DOI: https://doi.org/10.1101/2022.09.19.508502

Paper Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity

Kriukov, Dmitrii; Khrameeva, Ekaterina E.; Gladyshev, Vadim N. et al. · 2022 · DOI

Full title: Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity

Authors: Kriukov, Dmitrii; Khrameeva, Ekaterina E.; Gladyshev, Vadim N.; Dmitriev, Sergey E.; Tyshkovskiy, Alexander

Year: 2022

DOI: https://doi.org/10.1101/2022.12.12.520058

Paper Autonomous AI Agents Discover Aging Interventions from Millions of Molecular Profiles

Ying, Kejun; Tyshkovskiy, Alexander; Trapp, Alexandre et al. · 2023 · DOI

Full title: Autonomous AI Agents Discover Aging Interventions from Millions of Molecular Profiles

Authors: Ying, Kejun; Tyshkovskiy, Alexander; Trapp, Alexandre; Liu, Hanna; Moqri, Mahdi; Kerepesi, Csaba; Gladyshev, Vadim N.; Tskhay, Albina; Poganik, Jesse R.; Huang, Kexin; Qu, Yuanhao; Glubokov, Dmitrii; Jin, Cheng; Lee, Donghyun; Liu, Hanna; Leote, Carolina; Trapp, Alexandre; Camillo, Lucas Paulo de Lima; Kerepesi, Csaba; Moqri, Mahdi; Zhang, Odin; Jiang, Kaiyi; Galkin, Fedor; Zhavoronkov, Alex; Raamsdonk, Jeremy M. Van; Wang, Mengdi; Cong, Le; Regev, Aviv; Leskovec, Jure; Wyss-Coray, Tony; Gladyshev, Vadim N.

Year: 2023

DOI: https://doi.org/10.1101/2023.02.28.530532

Paper Multidimensional proteomics identifies molecular trajectories of cellular aging and rejuvenation

Leutert, Mario; Armstrong, Joseph O.; Ollodart, Anja R. et al. · 2023 · DOI

Full title: Multidimensional proteomics identifies molecular trajectories of cellular aging and rejuvenation

Authors: Leutert, Mario; Armstrong, Joseph O.; Ollodart, Anja R.; Hess, Kyle; Muir, Michael; Rodríguez‐Mias, Ricard A.; Kaeberlein, Matt; Dunham, Maitreya J.; Villén, Judit

Year: 2023

DOI: https://doi.org/10.1101/2023.03.09.531951

Paper A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

Lisonia Gkioni; Tobias Nespital; Carolina Monzó et al. · 2024 · bioRxiv · DOI

Full title: A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

Authors: Lisonia Gkioni; Tobias Nespital; Carolina Monzó; Jitin Bali; Taim Nassr; A. Cremer; A. Beyer; Heiko Backes; Sebastian Grönke; Linda Partridge

Year: 2024

Venue: bioRxiv

DOI: https://doi.org/10.1101/2024.07.25.605097

Paper Aging and immunity: the age-old tango.

Fernández Maestre, Inés; Harris, Alexander S; Amor, Corina · 2025 · Genes & development · DOI

Full title: Aging and immunity: the age-old tango.

Authors: Fernández Maestre, Inés; Harris, Alexander S; Amor, Corina

Year: 2025

Venue: Genes & development

DOI: https://doi.org/10.1101/gad.352644.125

Paper Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

Swindell, William R. · 2009 · BMC Genomics · DOI

Full title: Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

Authors: Swindell, William R.

Year: 2009

Venue: BMC Genomics

DOI: https://doi.org/10.1186/1471-2164-10-585

Paper Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

Al‐Azab, Mahmoud; Safi, Mohammed; Idiiatullina, Elina et al. · 2022 · Cellular & Molecular Biology Letters · DOI

Full title: Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

Authors: Al‐Azab, Mahmoud; Safi, Mohammed; Idiiatullina, Elina; Al‐Shaebi, Fadhl; Zaky, Mohamed Y.

Year: 2022

Venue: Cellular & Molecular Biology Letters

DOI: https://doi.org/10.1186/s11658-022-00366-0

Paper DNA methylation aging clocks: challenges and recommendations

Bell, Christopher G.; Lowe, Robert; Adams, Peter D. et al. · 2019 · Genome biology · DOI

Full title: DNA methylation aging clocks: challenges and recommendations

Authors: Bell, Christopher G.; Lowe, Robert; Adams, Peter D.; Baccarelli, Andrea; Beck, Stephan; Bell, Jordana T.; Christensen, Brock C.; Gladyshev, Vadim N.; Heijmans, Bastiaan T.; Horvath, Steve; Ideker, Trey; Issa, Jean‐Pierre J.; Kelsey, Karl T.; Marioni, Riccardo E.; Reik, Wolf; Relton, Caroline L.; Schalkwyk, Leonard C.; Teschendorff, Andrew E.; Wagner, Wolfgang; Zhang, Kang; Rakyan, Vardhman K.

Year: 2019

Venue: Genome biology

DOI: https://doi.org/10.1186/s13059-019-1824-y

Paper Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

Hãhn, Oliver; Stubbs, Thomas M.; Reik, Wolf et al. · 2018 · PLoS Genetics · DOI

Full title: Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

Authors: Hãhn, Oliver; Stubbs, Thomas M.; Reik, Wolf; Grönke, Sebastian; Beyer, Andreas; Partridge, Linda

Year: 2018

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1007766

Paper Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity.

Statzer, Cyril; Park, Ji Young Cecilia; Ewald, Collin Y · 2023 · Aging and disease · DOI

Full title: Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity.

Authors: Statzer, Cyril; Park, Ji Young Cecilia; Ewald, Collin Y

Year: 2023

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2022.1116

Paper Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies.

Zheng, Liyao; He, Shipei; Wang, Hong et al. · 2024 · Aging and disease · DOI

Full title: Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies.

Authors: Zheng, Liyao; He, Shipei; Wang, Hong; Li, Jinling; Liu, Yuanyuan; Liu, Sijia

Year: 2024

Venue: Aging and disease

DOI: https://doi.org/10.14336/AD.2024.0206

Paper Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics.

Alum, Esther Ugo; Izah, Sylvester Chibueze; Uti, Daniel Ejim et al. · 2025 · Drug design, development and therapy · DOI

Full title: Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics.

Authors: Alum, Esther Ugo; Izah, Sylvester Chibueze; Uti, Daniel Ejim; Ugwu, Okechukwu Paul-Chima; Betiang, Peter A; Basajja, Mariam; Ejemot-Nwadiaro, Regina Idu

Year: 2025

Venue: Drug design, development and therapy

DOI: https://doi.org/10.2147/DDDT.S543211

Paper Caloric restriction induced epigenetic effects on aging

Zhai, Jingfang; Kongsberg, William H.; Pan, Yinbo et al. · 2023 · Frontiers in Cell and Developmental Biology · DOI

Full title: Caloric restriction induced epigenetic effects on aging

Authors: Zhai, Jingfang; Kongsberg, William H.; Pan, Yinbo; Hao, Canhua; Wang, Xiaojing; Sun, Jie

Year: 2023

Venue: Frontiers in Cell and Developmental Biology

DOI: https://doi.org/10.3389/fcell.2022.1079920

Paper Agephagy - Adapting Autophagy for Health During Aging.

Stead, Eleanor R; Castillo-Quan, Jorge I; Miguel, Victoria Eugenia Martinez et al. · 2019 · Frontiers in cell and developmental biology · DOI

Full title: Agephagy - Adapting Autophagy for Health During Aging.

Authors: Stead, Eleanor R; Castillo-Quan, Jorge I; Miguel, Victoria Eugenia Martinez; Lujan, Celia; Ketteler, Robin; Kinghorn, Kerri J; Bjedov, Ivana

Year: 2019

Venue: Frontiers in cell and developmental biology

DOI: https://doi.org/10.3389/fcell.2019.00308

Paper Genetic Pathways of Aging and Their Relevance in the Dog as a Natural Model of Human Aging

Sándor, Sára; Kubinyi, Enikő · 2019 · Frontiers in Genetics · DOI

Full title: Genetic Pathways of Aging and Their Relevance in the Dog as a Natural Model of Human Aging

Authors: Sándor, Sára; Kubinyi, Enikő

Year: 2019

Venue: Frontiers in Genetics

DOI: https://doi.org/10.3389/fgene.2019.00948

Paper Improving the effectiveness of anti-aging modalities by using the constrained disorder principle-based management algorithms

Hurvitz, Noa; Elkhateeb, Narmine; Sigawi, Tal et al. · 2022 · Frontiers in Aging · DOI

Full title: Improving the effectiveness of anti-aging modalities by using the constrained disorder principle-based management algorithms

Authors: Hurvitz, Noa; Elkhateeb, Narmine; Sigawi, Tal; Rinsky‐Halivni, Lilah; Ilan, Yaron

Year: 2022

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2022.1044038

Paper Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models.

Inci, Nurcan; Kamali, Dilanur; Akyildiz, Erdogan Oguzhan et al. · 2022 · Frontiers in aging · DOI

Full title: Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models.

Authors: Inci, Nurcan; Kamali, Dilanur; Akyildiz, Erdogan Oguzhan; Tahir Turanli, Eda; Bozaykut, Perinur

Year: 2022

Venue: Frontiers in aging

DOI: https://doi.org/10.3389/fragi.2022.828058

Paper Translating Senotherapeutic Interventions into the Clinic with Emerging Proteomic Technologies.

Dey, Amit K; Banarjee, Reema; Boroumand, Mozhgan et al. · 2023 · Biology · DOI

Full title: Translating Senotherapeutic Interventions into the Clinic with Emerging Proteomic Technologies.

Authors: Dey, Amit K; Banarjee, Reema; Boroumand, Mozhgan; Rutherford, Delaney V; Strassheim, Quinn; Nyunt, Thedoe; Olinger, Bradley; Basisty, Nathan

Year: 2023

Venue: Biology

DOI: https://doi.org/10.3390/biology12101301

Paper The Janus-Faced Role of Lipid Droplets in Aging: Insights from the Cellular Perspective.

Bresgen, Nikolaus; Kovacs, Melanie; Lahnsteiner, Angelika et al. · 2023 · Biomolecules · DOI

Full title: The Janus-Faced Role of Lipid Droplets in Aging: Insights from the Cellular Perspective.

Authors: Bresgen, Nikolaus; Kovacs, Melanie; Lahnsteiner, Angelika; Felder, Thomas Klaus; Rinnerthaler, Mark

Year: 2023

Venue: Biomolecules

DOI: https://doi.org/10.3390/biom13060912

Paper Mechanistic Links Between the Gut Microbiome and Longevity Therapeutics

Noelia Garzon-Escamilla; Miriam Medina-Cardena; Preeti Roy et al. · 2026 · Biomedicines · DOI

Full title: Mechanistic Links Between the Gut Microbiome and Longevity Therapeutics

Authors: Noelia Garzon-Escamilla; Miriam Medina-Cardena; Preeti Roy; Jessica Trent; Joud Jamous; Yalini Somesan; Sandy J. Denslow

Year: 2026

Venue: Biomedicines

DOI: https://doi.org/10.3390/biomedicines14020316

Paper The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

Chung, Hae Young · 2021 · DOI

Full title: The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

Authors: Chung, Hae Young

Year: 2021

Paper Turning Back the Clock: A Retrospective Single-Blind Study on Brain Age Change in Response to Nutraceuticals Supplementation vs. Lifestyle Modifications

Fingelkurts, Andrew A.; Fingelkurts, Alexander A.; Fingelkurts, Alexander A. et al. · 2023 · Brain Sciences · DOI

Full title: Turning Back the Clock: A Retrospective Single-Blind Study on Brain Age Change in Response to Nutraceuticals Supplementation vs. Lifestyle Modifications

Authors: Fingelkurts, Andrew A.; Fingelkurts, Alexander A.; Fingelkurts, Alexander A.; Fingelkurts, Alexander A.

Year: 2023

Venue: Brain Sciences

DOI: https://doi.org/10.3390/brainsci13030520

Paper How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life Span

Galow, Anne-Marie; Peleg, Shahaf · 2022 · Cells · DOI

Full title: How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life Span

Authors: Galow, Anne-Marie; Peleg, Shahaf

Year: 2022

Venue: Cells

DOI: https://doi.org/10.3390/cells11030468

Paper Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.

Suda, Masayoshi; Paul, Karl H; Minamino, Tohru et al. · 2023 · Cells · DOI

Full title: Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.

Authors: Suda, Masayoshi; Paul, Karl H; Minamino, Tohru; Miller, Jordan D; Lerman, Amir; Ellison-Hughes, Georgina M; Tchkonia, Tamar; Kirkland, James L

Year: 2023

Venue: Cells

DOI: https://doi.org/10.3390/cells12091296

Paper Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments

Zuo, Li; Prather, Evan R.; Stetskiv, Mykola et al. · 2019 · International Journal of Molecular Sciences · DOI

Full title: Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments

Authors: Zuo, Li; Prather, Evan R.; Stetskiv, Mykola; Garrison, Davis E.; Meade, James R.; Peace, Timotheus I.; Zhou, Tingyang

Year: 2019

Venue: International Journal of Molecular Sciences

DOI: https://doi.org/10.3390/ijms20184472

Paper Genome-Protecting Compounds as Potential Geroprotectors.

Proshkina, Ekaterina; Shaposhnikov, Mikhail; Moskalev, Alexey · 2020 · International journal of molecular sciences · DOI

Full title: Genome-Protecting Compounds as Potential Geroprotectors.

Authors: Proshkina, Ekaterina; Shaposhnikov, Mikhail; Moskalev, Alexey

Year: 2020

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms21124484

Paper Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks.

Yusri, Khalishah; Kumar, Sanjay; Fong, Sheng et al. · 2024 · International journal of molecular sciences · DOI

Full title: Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks.

Authors: Yusri, Khalishah; Kumar, Sanjay; Fong, Sheng; Gruber, Jan; Sorrentino, Vincenzo

Year: 2024

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms25126793

Paper Hepatocytes as Model for Investigating Natural Senotherapeutic Compounds and Their Effects on Cell Cycle Dynamics and Genome Stability.

Fizikova, Anastasia; Prokhorova, Anna; Churikova, Daria et al. · 2025 · International journal of molecular sciences · DOI

Full title: Hepatocytes as Model for Investigating Natural Senotherapeutic Compounds and Their Effects on Cell Cycle Dynamics and Genome Stability.

Authors: Fizikova, Anastasia; Prokhorova, Anna; Churikova, Daria; Konstantinov, Zahar; Ivanov, Roman; Karabelsky, Alexander; Rybtsov, Stanislav

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26146794

Paper Which Approach to Choose to Counteract Musculoskeletal Aging? A Comprehensive Review on the Multiple Effects of Exercise.

Falvino, Angela; Bonanni, Roberto; Tarantino, Umberto et al. · 2025 · International journal of molecular sciences · DOI

Full title: Which Approach to Choose to Counteract Musculoskeletal Aging? A Comprehensive Review on the Multiple Effects of Exercise.

Authors: Falvino, Angela; Bonanni, Roberto; Tarantino, Umberto; Tancredi, Virginia; Cariati, Ida

Year: 2025

Venue: International journal of molecular sciences

DOI: https://doi.org/10.3390/ijms26157573

Paper Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases

Fekete, Mónika; Szarvas, Z; Fazekas‐Pongor, Vince et al. · 2022 · Nutrients · DOI

Full title: Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases

Authors: Fekete, Mónika; Szarvas, Z; Fazekas‐Pongor, Vince; Fehér, Ágnes; Csípő, Tamás; Forrai, Judit; Dósa, Norbert; Péterfi, Anna; Lehoczki, Andrea; Tarantini, Stefano; Varga, János Tamás

Year: 2022

Venue: Nutrients

DOI: https://doi.org/10.3390/nu15010047

Paper Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs

Bulterijs, Sven; Braeckman, Bart P. · 2020 · Pharmaceuticals · DOI

Full title: Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs

Authors: Bulterijs, Sven; Braeckman, Bart P.

Year: 2020

Venue: Pharmaceuticals

DOI: https://doi.org/10.3390/ph13080164

Paper Epigenetic Clock, Circadian Rhythms and Cell Aging

Samoilova, Ekaterina M.; Belopasov, Vladimir V.; Ekusheva, Evgenia V. et al. · 2021 · Preprints.org · DOI

Full title: Epigenetic Clock, Circadian Rhythms and Cell Aging

Authors: Samoilova, Ekaterina M.; Belopasov, Vladimir V.; Ekusheva, Evgenia V.; Zhang, Chao; Troitskiy, A. V.; Баклаушев, Владимир П.

Year: 2021

Venue: Preprints.org

DOI: https://doi.org/10.20944/preprints202109.0189.v1

Paper Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

Statsenko, Yauhen; Kuznetsov, Nikolai V.; Morozova, Daria et al. · 2023 · Cells · DOI

Full title: Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

Year: 2023

Venue: Cells

DOI: https://doi.org/10.20944/preprints202512.0724.v1

Paper The Integration Breakthrough: Sequenced Rapamycin, Senolytics, and NAD+ Boosters for Enhanced Anti-Aging Based on Cellular Energy Principles

Milani, M · 2025 · Preprints.org · DOI

Full title: The Integration Breakthrough: Sequenced Rapamycin, Senolytics, and NAD+ Boosters for Enhanced Anti-Aging Based on Cellular Energy Principles

Authors: Milani, M

Year: 2025

Venue: Preprints.org

Paper Geroprotectors as a therapeutic strategy for COPD - where are we now?

Miłkowska-Dymanowska, Joanna; Białas, Adam J; Makowska, Joanna et al. · 2017 · Clinical interventions in aging · DOI

Full title: Geroprotectors as a therapeutic strategy for COPD - where are we now?

Authors: Miłkowska-Dymanowska, Joanna; Białas, Adam J; Makowska, Joanna; Wardzynska, Aleksandra; Górski, Paweł; Piotrowski, Wojciech J

Year: 2017

Venue: Clinical interventions in aging

DOI: https://doi.org/10.2147/CIA.S142483

Paper Animal models of frailty: current applications in clinical research

Kane, Alice E.; Hilmer, Sarah N.; Mach, John et al. · 2016 · Clinical Interventions in Aging · DOI

Full title: Animal models of frailty: current applications in clinical research

Authors: Kane, Alice E.; Hilmer, Sarah N.; Mach, John; Mitchell, Sarah J.; Cabo, Rafael de; Howlett, Susan E.

Year: 2016

Venue: Clinical Interventions in Aging

DOI: https://doi.org/10.2147/cia.s105714

Paper Does eating less make you live longer and better? An update on calorie restriction

Picca, Anna; Pesce, Vito; Lezza, Angela Maria Serena · 2017 · Clinical Interventions in Aging · DOI

Full title: Does eating less make you live longer and better? An update on calorie restriction

Authors: Picca, Anna; Pesce, Vito; Lezza, Angela Maria Serena

Year: 2017

Venue: Clinical Interventions in Aging

DOI: https://doi.org/10.2147/cia.s126458

Paper Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease.

Ito, Kazuhiro; Colley, Thomas; Mercado, Nicolas · 2012 · International journal of chronic obstructive pulmonary disease · DOI

Full title: Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease.

Authors: Ito, Kazuhiro; Colley, Thomas; Mercado, Nicolas

Year: 2012

Venue: International journal of chronic obstructive pulmonary disease

DOI: https://doi.org/10.2147/COPD.S28250

Paper The Role and Application of the AMPK-Sirtuins Network in Cellular Senescence.

Han, Yukun; Liu, Yifan; Zhang, Yanhua et al. · 2023 · Frontiers in bioscience (Landmark edition) · DOI

Full title: The Role and Application of the AMPK-Sirtuins Network in Cellular Senescence.

Authors: Han, Yukun; Liu, Yifan; Zhang, Yanhua; Wang, Wei; Lv, Tongtong; Huang, Jinbai; Peng, Xiaochun

Year: 2023

Venue: Frontiers in bioscience (Landmark edition)

DOI: https://doi.org/10.31083/j.fbl2810250

Paper NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations.

Driscoll, Monica; Sedore, Christine A; Onken, Brian et al. · 2025 · GeroScience · DOI

Full title: NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations.

Authors: Driscoll, Monica; Sedore, Christine A; Onken, Brian; Coleman-Hulbert, Anna L; Johnson, Erik; Phillips, Patrick C; Lithgow, Gordon

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-01627-4

Paper Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Marisa Ferreira-Marques; C. Aveleira; S. Carmo-Silva et al. · 2016 · Aging · DOI

Full title: Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Authors: Marisa Ferreira-Marques; C. Aveleira; S. Carmo-Silva; M. Botelho; Luís Pereira de Almeida; C. Cavadas

Year: 2016

Venue: Aging

DOI: https://doi.org/10.18632/aging.100996

Paper In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.

Aliper, Alexander; Belikov, Aleksey V; Garazha, Andrew et al. · 2016 · Aging · DOI

Full title: In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.

Authors: Aliper, Alexander; Belikov, Aleksey V; Garazha, Andrew; Jellen, Leslie; Artemov, Artem; Suntsova, Maria; Ivanova, Alena; Venkova, Larisa; Borisov, Nicolas; Buzdin, Anton; Mamoshina, Polina; Putin, Evgeny; Swick, Andrew G; Moskalev, Alexey; Zhavoronkov, Alex

Year: 2016

Venue: Aging

DOI: https://doi.org/10.18632/aging.101047

Thesis The effect of AMPK activation on Alzheimer's-like symptoms in APP mice

DiTacchio, Kacee · 2011 · University of California, San Diego (UCSD) · DOI

Full title: The effect of AMPK activation on Alzheimer's-like symptoms in APP mice

Authors: DiTacchio, Kacee

Year: 2011

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0rh8k3sg

Thesis Modifying Acetylation in Skeletal Muscle to Improve Health- and Life- Span

Pathak, Suraj J. · 2023 · University of California, Davis · DOI

Full title: Modifying Acetylation in Skeletal Muscle to Improve Health- and Life- Span

Authors: Pathak, Suraj J.

Year: 2023

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/8x64t4xz

Thesis CIRCADIAN MECHANISMS OF CALORIE RESTRICTION IN DELAYING AGING

Makwana, Kuldeep, Makwana · 2018 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: CIRCADIAN MECHANISMS OF CALORIE RESTRICTION IN DELAYING AGING

Authors: Makwana, Kuldeep, Makwana

Year: 2018

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=csu1543844626233009

Thesis TEMPORAL FASTING AND REDUCED CALORIES INDEPENDENTLY CONTRIBUTE TO METABOLIC BENEFITS OF CALORIC RESTRICTION

Velingkaar, Nikkhil · 2019 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: TEMPORAL FASTING AND REDUCED CALORIES INDEPENDENTLY CONTRIBUTE TO METABOLIC BENEFITS OF CALORIC RESTRICTION

Authors: Velingkaar, Nikkhil

Year: 2019

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=csu1568132919804719

Thesis Age and Sex-Specific Effect of Caloric Restriction on Circadian Clock and Longevity-Associated Gene Expression

Astafev, Artem Andreyevich · 2017 · OhioLINK Electronic Theses and Dissertations · DOI

Full title: Age and Sex-Specific Effect of Caloric Restriction on Circadian Clock and Longevity-Associated Gene Expression

Authors: Astafev, Artem Andreyevich

Year: 2017

Venue: OhioLINK Electronic Theses and Dissertations

DOI: http://rave.ohiolink.edu/etdc/view?acc_num=csu1508436079666819

Thesis Metabolomics and proteomics of dietary restriction in Drosophila

Charles, Alexander J. · 2022 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: Metabolomics and proteomics of dietary restriction in Drosophila

Authors: Charles, Alexander J.

Year: 2022

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/32541/1/Metabolomics%20and%20proteomics%20of%20dietary%20restriction%20in%20Drosophila.pdf

Thesis The Impact of Nutrient Restriction and Metformin Treatment on Genome Structure and Function in Hutchinson-Gilford Progeria Syndrome (HGPS) Fibroblasts

Gillespie, Zoe E · 2022 · University of Saskatchewan - HARVEST · DOI

Full title: The Impact of Nutrient Restriction and Metformin Treatment on Genome Structure and Function in Hutchinson-Gilford Progeria Syndrome (HGPS) Fibroblasts

Authors: Gillespie, Zoe E

Year: 2022

Venue: University of Saskatchewan - HARVEST

DOI: https://hdl.handle.net/10388/13823

Thesis The Impact of Rapamycin and Metformin on Genome Organization and Function in Normal Human Fibroblasts

Gillespie, Zoe Elizabeth 1993- · 2017 · University of Saskatchewan - HARVEST · DOI

Full title: The Impact of Rapamycin and Metformin on Genome Organization and Function in Normal Human Fibroblasts

Authors: Gillespie, Zoe Elizabeth 1993-

Year: 2017

Venue: University of Saskatchewan - HARVEST

DOI: http://hdl.handle.net/10388/7709

Thesis NAD(+) homeostasis in health and disease

Katsyuba, Elena; Romani, Mario; Hofer, Dina et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD(+) homeostasis in health and disease

Authors: Katsyuba, Elena; Romani, Mario; Hofer, Dina; Auwerx, Johan

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/167067

Thesis Balancing NAD(+) deficits with nicotinamide riboside: therapeutic possibilities and limitations

Cercillieux, Angelique; Ciarlo, Eleonora; Canto, Carles · 2022 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Balancing NAD(+) deficits with nicotinamide riboside: therapeutic possibilities and limitations

Authors: Cercillieux, Angelique; Ciarlo, Eleonora; Canto, Carles

Year: 2022

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/190313

Thesis Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Jiang, Q; Liu, J; Huang, S et al. · 2025 · University of Melbourne · DOI

Full title: Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Authors: Jiang, Q; Liu, J; Huang, S; Wang, XY; Chen, X; Liu, GH; Ye, K; Song, W; Masters, CL; Wang, J; Wang, YJ

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360219

Thesis Rilmenidine is a Calorie Restriction Mimetic that Improves Survival and Indicators of Healthy Ageing in C. elegans via a Novel IRAS Ortholog, f13e9.1

Bennett, Dominic · 2020 · University of Liverpool · DOI

Full title: Rilmenidine is a Calorie Restriction Mimetic that Improves Survival and Indicators of Healthy Ageing in C. elegans via a Novel IRAS Ortholog, f13e9.1

Authors: Bennett, Dominic

Year: 2020

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3081842/1/201154991_Sep2019.pdf

Thesis Transcriptomics profiling to study the role of noncoding RNAs in muscle ageing and its modulation by calorie restriction

Altab, Gulam · 2023 · University of Liverpool · DOI

Full title: Transcriptomics profiling to study the role of noncoding RNAs in muscle ageing and its modulation by calorie restriction

Authors: Altab, Gulam

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3173022/1/201092584_June2023.pdf

Thesis Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor et al. · 2018 · Colorado State University · DOI

Full title: Novel insights into protein synthesis rates in the brain following two lifespan-extending treatments

Authors: Reid, Justin, author; Hamilton, Karyn, advisor; Miller, Benjamin, advisor; Tsunoda, Susan, committee member

Year: 2018

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/191325

Thesis Protein synthesis in slowed aging: insights into shared characteristics of long-lived mouse models

Drake, Joshua Chadwick, author; Miller, Benjamin F., advisor; Hamilton, Karyn L., advisor et al. · 2007 · Colorado State University · DOI

Full title: Protein synthesis in slowed aging: insights into shared characteristics of long-lived mouse models

Authors: Drake, Joshua Chadwick, author; Miller, Benjamin F., advisor; Hamilton, Karyn L., advisor; Wilusz, Carol J., committee member; Hickey, Matthew S., committee member

Year: 2007

Venue: Colorado State University

DOI: http://hdl.handle.net/10217/82613

Thesis The impact of time-restricted eating on circulating factors, insulin sensitivity and circadian rhythms

Kennedy, Devin, author; Broussard, Josiane, advisor; Braun, Barry, committee member et al. · 2021 · Colorado State University · DOI

Full title: The impact of time-restricted eating on circulating factors, insulin sensitivity and circadian rhythms

Authors: Kennedy, Devin, author; Broussard, Josiane, advisor; Braun, Barry, committee member; Stephens, Jaclyn, committee member

Year: 2021

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/219550

Thesis Treatment with rapamycin or rapamycin in combination with metformin contributes to mechanisms of mitochondrial proteostasis in vivo and in vitro

Wolff, Christopher Andrew, author; Hamilton, Karyn L., advisor; Miller, Benjamin F., advisor et al. · 2018 · Colorado State University · DOI

Full title: Treatment with rapamycin or rapamycin in combination with metformin contributes to mechanisms of mitochondrial proteostasis in vivo and in vitro

Authors: Wolff, Christopher Andrew, author; Hamilton, Karyn L., advisor; Miller, Benjamin F., advisor; Hickey, Matthew, committee member; Pagliassotti, Michael, committee member

Year: 2018

Venue: Colorado State University

DOI: https://hdl.handle.net/10217/189383

Thesis Oxidative and energetic stress: regulation of Nrf2 and mitochondrial biogenesis for slowed aging interventions

Bruns, Danielle Reuland, author; Hamilton, Karyn L., advisor; Miller, Benjamin F., advisor et al. · 2007 · Colorado State University · DOI

Full title: Oxidative and energetic stress: regulation of Nrf2 and mitochondrial biogenesis for slowed aging interventions

Authors: Bruns, Danielle Reuland, author; Hamilton, Karyn L., advisor; Miller, Benjamin F., advisor; Wilusz, Carol J., committee member; Pagliassotti, Michael J., committee member

Year: 2007

Venue: Colorado State University

DOI: http://hdl.handle.net/10217/80934

Thesis EXPLORING THE ROLE OF NAD+ HOMEOSTASIS IN CARDIAC HYPERTROPHY AND FUNCTIONAL ABNORMALITIES IN A MOUSE MODEL OF FRIEDREICH’S ATAXIA

Perry, Caroline, E · 2024 · University of Pennsylvania · DOI

Full title: EXPLORING THE ROLE OF NAD+ HOMEOSTASIS IN CARDIAC HYPERTROPHY AND FUNCTIONAL ABNORMALITIES IN A MOUSE MODEL OF FRIEDREICH’S ATAXIA

Authors: Perry, Caroline, E

Year: 2024

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/60070

Thesis The Effects of Aging on Circadian Rhythms and the Gut Microbiome

Litichevskiy, Lev · 2024 · University of Pennsylvania · DOI

Full title: The Effects of Aging on Circadian Rhythms and the Gut Microbiome

Authors: Litichevskiy, Lev

Year: 2024

Venue: University of Pennsylvania

DOI: https://repository.upenn.edu/handle/20.500.14332/60224

Thesis On the measurement and systemic relevance of extracellular nicotinamide adenine dinucleotide in human plasma

Brunnbauer, Philipp · 2020 · Freie Universität Berlin (Refubium) · DOI

Full title: On the measurement and systemic relevance of extracellular nicotinamide adenine dinucleotide in human plasma

Authors: Brunnbauer, Philipp

Year: 2020

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/26843

Thesis Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Gariani, K; Menzies, KJ; Ryu, D et al. · 2022 · University of Melbourne · DOI

Full title: Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Authors: Gariani, K; Menzies, KJ; Ryu, D; Wegner, CJ; Wang, X; Ropelle, ER; Moullan, N; Zhang, H; Perino, A; Lemos, V; Kim, B; Park, YK; Piersigilli, A; Pham, TX; Yang, Y; Ku, CS; Koo, SI; Fomitchova, A; Cantó, C; Schoonjans, K; Sauve, AA; Lee, JY; Auwerx, J

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/304421

Thesis The Role of Oxidative Stress and Inflammation in Cardiovascular Aging

Wu, J; Xia, S; Kalionis, B et al. · 2021 · University of Melbourne · DOI

Full title: The Role of Oxidative Stress and Inflammation in Cardiovascular Aging

Authors: Wu, J; Xia, S; Kalionis, B; Wan, W; Sun, T

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/263192

Thesis Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities

Pulito, C; Mori, F; Sacconi, A et al. · 2021 · University of Melbourne · DOI

Full title: Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities

Authors: Pulito, C; Mori, F; Sacconi, A; Goeman, F; Ferraiuolo, M; Pasanisi, P; Campagnoli, C; Berrino, F; Fanciulli, M; Ford, RJ; Levrero, M; Pediconi, N; Ciuffreda, L; Milella, M; Steinberg, GR; Cioce, M; Muti, P; Strano, S; Blandino, G

Year: 2021

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/270484

Thesis Consumption of a low glycaemic index diet in late life extends lifespan of Balb/c mice with differential effects on DNA damage.

Nankervis, SA; Mitchell, JM; Charchar, FJ et al. · 2022 · University of Melbourne · DOI

Full title: Consumption of a low glycaemic index diet in late life extends lifespan of Balb/c mice with differential effects on DNA damage.

Authors: Nankervis, SA; Mitchell, JM; Charchar, FJ; McGlynn, MA; Lewandowski, PA

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/305173

Thesis Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

Hajj-Boutros, G; Faust, A; Muscedere, J et al. · 2024 · University of Melbourne · DOI

Full title: Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

Authors: Hajj-Boutros, G; Faust, A; Muscedere, J; Kim, P; Abumrad, N; Chevalier, S; Aubertin-Leheudre, M; Bergman, H; Bowdish, D; Burford, J; Carrington-Lawrence, S; Côté, H; Dawe, DE; Barreto, PDS; Farrelly, C; Fowler, R; Gouspillou, G; Harrington, L; Lautrup, S; Howlett, S; Imani, M; Kirkland, J; Kuchel, G; Mallette, FA; Morais, JA; Newman, JC; Pullman, D; Sierra, F; Van Raamsdonk, J; Watt, J; Rylett, RJ; Duque, G

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/353797

Thesis Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an -glucosidase inhibitor or a Nrf2-inducer

Strong, R; Miller, RA; Antebi, A et al. · 2016 · University of Liverpool · DOI

Full title: Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an -glucosidase inhibitor or a Nrf2-inducer

Authors: Strong, R; Miller, RA; Antebi, A; Astle, CM; Bogue, M; Denzel, MS; Fernandez, E; Flurkey, K; Hamilton, KL; Lamming, DW; Javors, MA; de Magalhaes, JP; Martinez, PA; McCord, JM; Miller, BF; Muller, M; Nelson, JF; Ndukum, J; Rainger, GE; Richardson, A; Sabatini, DM; Salmon, AB; Simpkins, JW; Steegenga, WT; Nadon, NL; Harrison, DE

Year: 2016

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3002106/1/acel12496_inpress.pdf

Thesis eNODAL: an experimentally guided nutriomics data clustering method to unravel complex drug–diet interactions

Xu, X; Senior, AM; Le Couteur, DG et al. · 2025 · University of Melbourne · DOI

Full title: eNODAL: an experimentally guided nutriomics data clustering method to unravel complex drug–diet interactions

Authors: Xu, X; Senior, AM; Le Couteur, DG; Cogger, VC; Raubenheimer, D; James, DE; Parker, B; Simpson, SJ; Muller, S; Yang, JYH

Year: 2025

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/360055

Thesis Targeting ageing with rapamycin and its derivatives in humans: a systematic review

Lee, DJW; Hodzic Kuerec, A; Maier, AB · 2024 · University of Melbourne · DOI

Full title: Targeting ageing with rapamycin and its derivatives in humans: a systematic review

Authors: Lee, DJW; Hodzic Kuerec, A; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/351983

Thesis Establishing healthy longevity clinics in publicly funded hospitals

Bonnes, SLR; Strauss, T; Palmer, AK et al. · 2024 · University of Melbourne · DOI

Full title: Establishing healthy longevity clinics in publicly funded hospitals

Authors: Bonnes, SLR; Strauss, T; Palmer, AK; Hurt, RT; Island, L; Goshen, A; Wang, LYT; Kirkland, JL; Bischof, E; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/352521

Thesis Machine learning for predicting lifespan-extending chemical compounds

Barardo, Diogo G; Newby, Danielle; Thornton, Daniel et al. · 2017 · University of Liverpool · DOI

Full title: Machine learning for predicting lifespan-extending chemical compounds

Authors: Barardo, Diogo G; Newby, Danielle; Thornton, Daniel; Ghafourian, Taravat; de Magalhaes, Joao Pedro; Freitas, Alex A

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3008936/1/AGING_2017.pdf

Thesis Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor

Bennett, Dominic F; Goyala, Anita; Statzer, Cyril et al. · 2023 · University of Liverpool · DOI

Full title: Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor

Authors: Bennett, Dominic F; Goyala, Anita; Statzer, Cyril; Beckett, Charles W; Tyshkovskiy, Alexander; Gladyshev, Vadim N; Ewald, Collin Y; de Magalhaes, Joao Pedro

Year: 2023

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3170453/1/Rilmenidine%20extends%20lifespan%20and%20healthspan%20in%20Caenorhabditis%20elegans%20via%20a%20nischarin%20I1-imidazoline%20receptor.pdf

Thesis Machine learning-based predictions of dietary restriction associations across ageing-related genes

Magdaleno, Gustavo Daniel Vega; Bespalov, Vladislav; Zheng, Yalin et al. · 2022 · University of Liverpool · DOI

Full title: Machine learning-based predictions of dietary restriction associations across ageing-related genes

Authors: Magdaleno, Gustavo Daniel Vega; Bespalov, Vladislav; Zheng, Yalin; Freitas, Alex A; de Magalhaes, Joao Pedro

Year: 2022

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3146950/1/Machine%20learning-based%20predictions%20of%20dietary%20restriction%20associations%20across%20ageing-related%20genes.pdf

Thesis Metabolomics of human fasting: new insights about old questions

Kondoh, Hiroshi; Teruya, Takayuki; Yanagida, Mitsuhiro · 2020 · Okinawa Institute of Science and Technology (OIST) · DOI

Full title: Metabolomics of human fasting: new insights about old questions

Authors: Kondoh, Hiroshi; Teruya, Takayuki; Yanagida, Mitsuhiro

Year: 2020

Venue: Okinawa Institute of Science and Technology (OIST)

DOI: https://oist.repo.nii.ac.jp/record/1760/files/rsob.200176.pdf

Thesis Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds

Gupta, Vipul; Crudu, Alina; Matsuoka, Yukiko et al. · 2019 · Okinawa Institute of Science and Technology (OIST) · DOI

Full title: Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds

Authors: Gupta, Vipul; Crudu, Alina; Matsuoka, Yukiko; Ghosh, Samik; Rozot, Roger; Marat, Xavier; Jäger, Sibylle; Kitano, Hiroaki; Breton, Lionel

Year: 2019

Venue: Okinawa Institute of Science and Technology (OIST)

DOI: https://oist.repo.nii.ac.jp/record/1194/files/Gupta-2019-Multi-dimensional computational pip.pdf

Thesis Whole Blood Metabolomics in Aging Research

Kondoh, Hiroshi; Kameda, Masahiro; Yanagida, Mitsuhiro · 2020 · Okinawa Institute of Science and Technology (OIST) · DOI

Full title: Whole Blood Metabolomics in Aging Research

Authors: Kondoh, Hiroshi; Kameda, Masahiro; Yanagida, Mitsuhiro

Year: 2020

Venue: Okinawa Institute of Science and Technology (OIST)

DOI: https://oist.repo.nii.ac.jp/record/1921/files/Kondoh-2021-Whole Blood Metabolomics in Aging.pdf

Thesis A Comparison of the Impact of Restrictive Diets on the Gastrointestinal Tract of Mice

Gregor, András (University of Vienna); Duszka, Kalina (University of Vienna); Auernigg-Haselmaier, Sandra (University of Vienna) et al. · 2022 · University of Veterinary Medicine Vienna (Vetmeduni Vienna) · DOI

Full title: A Comparison of the Impact of Restrictive Diets on the Gastrointestinal Tract of Mice

Authors: Gregor, András (University of Vienna); Duszka, Kalina (University of Vienna); Auernigg-Haselmaier, Sandra (University of Vienna); Huber, Laura (University of Vienna); König, Jürgen (University of Vienna); Longo, Valter D. (USC Longevity Institute); Kofler, Barbara (University Hospital of the Paracelsus Medical University Salzburg); Ogris, Manfred (University of Vienna); Somoza, Veronika (Technical University of Munich); Dunkel, Andreas (Technical University of Munich); Billerhart, Magdalena (University of Vienna); Sternberg, Felix (University of Veterinary Medicine Vienna)

Year: 2022

Venue: University of Veterinary Medicine Vienna (Vetmeduni Vienna)

DOI: https://phaidra.vetmeduni.ac.at/o:2070

Thesis Vliv kalorické restrikce na neuroplasticitu

Sonina, Alisa · 2023 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Vliv kalorické restrikce na neuroplasticitu

Authors: Sonina, Alisa

Year: 2023

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/184690

Thesis Autofagie jako klíčový mediátor benefičních účinků kalorické restrikce

Kačinská, Irena · 2021 · Charles University Prague (Univerzita Karlova) · DOI

Full title: Autofagie jako klíčový mediátor benefičních účinků kalorické restrikce

Authors: Kačinská, Irena

Year: 2021

Venue: Charles University Prague (Univerzita Karlova)

DOI: http://hdl.handle.net/20.500.11956/126313

Thesis Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

Membrez, Mathieu; Migliavacca, Eugenia; Christen, Stefan et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

Authors: Membrez, Mathieu; Migliavacca, Eugenia; Christen, Stefan; Yaku, Keisuke; Trieu, Jennifer; Lee, Alaina K.; Morandini, Francesco; Giner, Maria Pilar; Stiner, Jade; Makarov, Mikhail V.; Garratt, Emma S.; Vasiloglou, Maria F.; Chanvillard, Lucie; Dalbram, Emilie; Ehrlich, Amy M.; Sanchez-Garcia, Jose Luis; Canto, Carles; Karagounis, Leonidas G.; Treebak, Jonas T.; Migaud, Marie E.; Heshmat, Ramin; Razi, Farideh; Karnani, Neerja; Ostovar, Afshin; Farzadfar, Farshad; Tay, Stacey K. H.; Sanders, Matthew J.; Lillycrop, Karen A.; Godfrey, Keith M.; Nakagawa, Takashi; Moco, Sofia; Koopman, Rene; Lynch, Gordon S.; Sorrentino, Vincenzo; Feige, Jerome N.

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/206969

Thesis Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice

Kiesworo, Kevin; Agius, Thomas; Macarthur, Michael R. et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice

Authors: Kiesworo, Kevin; Agius, Thomas; Macarthur, Michael R.; Lambelet, Martine; Lyon, Arnaud; Zhang, Jing; Turiel, Guillermo; Fan, Zheng; d'Almeida, Sènan; Uygun, Korkut; Yeh, Heidi; Déglise, Sébastien; de Bock, Katrien; Mitchell, Sarah J.; Ocampo, Alejandro; Allagnat, Florent; Longchamp, Alban

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/250537

Thesis NAD + boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Wang, Yu Jen; Gaul, Daniel S.; Gorica, Era et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD + boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Authors: Wang, Yu Jen; Gaul, Daniel S.; Gorica, Era; Pahla, Jürgen; Wang, Zeneng; Mohammed, Shafeeq A.; Dahlby, Tina; Dietrich, Elisa; Osto, Elena; Gariani, Karim; Costantino, Sarah; Winnik, Stephan; Stein, Sokrates; Hazen, Stanley L.; Ruschitzka, Frank; Auwerx, Johan; Matter, Christian M.

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/249287

Thesis Niacin: an old lipid drug in a new NAD(+) dress

Romani, Mario; Hofer, Dina Carina; Katsyuba, Elena et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Niacin: an old lipid drug in a new NAD(+) dress

Authors: Romani, Mario; Hofer, Dina Carina; Katsyuba, Elena; Auwerx, Johan

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/156860

Thesis Cross-species functional modules link proteostasis to human normal aging

Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Cross-species functional modules link proteostasis to human normal aging

Authors: Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo; Kutalik, Zoltan; Auwerx, Johan; Robinson-Rechavi, Marc

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/160690

Thesis NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Romani, Mario; Sorrentino, Vincenzo; Oh, Changmyung et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Authors: Romani, Mario; Sorrentino, Vincenzo; Oh, Changmyung; Li, Hao; Imamura de Lima, Tanes; Zhang, Hongbo; Shong, Minho; Auwerx, Johan

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/176007

Thesis A Method to Monitor the NAD(+) Metabolome-From Mechanistic to Clinical Applications

Giner, Maria Pilar; Christen, Stefan; Bartova, Simona et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A Method to Monitor the NAD(+) Metabolome-From Mechanistic to Clinical Applications

Authors: Giner, Maria Pilar; Christen, Stefan; Bartova, Simona; Makarov, Mikhail, V; Migaud, Marie E.; Canto, Carles; Moco, Sofia

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/182846

Thesis NAD(+) Precursors: A Questionable Redundancy

Canto, Carles · 2022 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD(+) Precursors: A Questionable Redundancy

Authors: Canto, Carles

Year: 2022

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/189991

Thesis A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor

Giroud-Gerbetant, Judith; Joffraud, Magali; Giner, Maria Pilar et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor

Authors: Giroud-Gerbetant, Judith; Joffraud, Magali; Giner, Maria Pilar; Cercillieux, Angelique; Bartova, Simona; Makarov, Mikhail V.; Zapata-Perez, Ruben; Sanchez-Garcia, Jose L.; Houtkooper, Riekelt H.; Migaud, Marie E.; Moco, Sofia; Canto, Carles

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/164148

Thesis SRT1720 improves survival and healthspan of obese mice

Minor, Robin K.; Baur, Joseph A.; Gomes, Ana P. et al. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: SRT1720 improves survival and healthspan of obese mice

Authors: Minor, Robin K.; Baur, Joseph A.; Gomes, Ana P.; Ward, Theresa M.; Csiszar, Anna; Mercken, Evi M.; Abdelmohsen, Kotb; Shin, Yu-Kyong; Canto, Carles; Scheibye-Knudsen, Morten; Krawczyk, Melissa; Irusta, Pablo M.; Martin-Montalvo, Alejandro; Hubbard, Basil P.; Zhang, Yongqing; Lehrmann, Elin; White, Alexa A.; Price, Nathan L.; Swindell, William R.; Pearson, Kevin J.; Becker, Kevin G.; Bohr, Vilhelm A.; Gorospe, Myriam; Egan, Josephine M.; Talan, Mark I.; Auwerx, Johan; Westphal, Christoph H.; Ellis, James L.; Ungvari, Zoltan; Vlasuk, George P.; Elliott, Peter J.; Sinclair, David A.; de Cabo, Rafael

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/73379

Thesis Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

Maxwell, Michele M.; Zaldivar-Jolissaint, Julien Francisco; Mai, Antonello et al. · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

Authors: Maxwell, Michele M.; Zaldivar-Jolissaint, Julien Francisco; Mai, Antonello; Outeiro, Tiago F.; Kazanstev, Aleksey G.

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/84252

Thesis SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting

Boutant, Marie; Kulkarni, Sameer S.; Joffraud, Magali et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting

Authors: Boutant, Marie; Kulkarni, Sameer S.; Joffraud, Magali; Raymond, Frederic; Metairon, Sylviane; Descombes, Patrick; Canto, Carles

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/125255

Thesis NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Ratajczak, Joanna; Joffraud, Magali; Trammell, Samuel A. J. et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Authors: Ratajczak, Joanna; Joffraud, Magali; Trammell, Samuel A. J.; Ras, Rosa; Canela, Nuria; Boutant, Marie; Kulkarni, Sameer S.; Rodrigues, Marcelo; Redpath, Philip; Migaud, Marie E.; Auwerx, Johan; Yanes, Oscar; Brenner, Charles; Canto, Carles

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/131397

Thesis Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

Mcdaid, Aaron F.; Joshi, Peter K.; Porcu, Eleonora et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

Authors: Mcdaid, Aaron F.; Joshi, Peter K.; Porcu, Eleonora; Komljenovic, Andrea; Li, Hao; Sorrentino, Vincenzo; Litovchenko, Maria; Bevers, Roel P. J.; Rueger, Sina; Reymond, Alexandre; Bochud, Murielle; Deplancke, Bart; Williams, Robert W.; Robinson-Rechavi, Marc; Paccaud, Fred; Rousson, Valentin; Auwerx, Johan; Wilson, James F.; Kutalik, Zoltan

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/140172

Thesis Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome?

Ford, RJ; Desjardins, EM; Steinberg, GR · 2020 · University of Melbourne · DOI

Full title: Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome?

Authors: Ford, RJ; Desjardins, EM; Steinberg, GR

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/257100

Thesis Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism

Kowaltowski, Alicia Juliana · 2013 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism

Authors: Kowaltowski, Alicia Juliana

Year: 2013

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1371/journal.pone.0056388

Thesis STUDIO DELL'EFFETTO PREVENTIVO DELLA METFORMINA SUI DANNI ASSOCIATI ALLA SEDENTARIETA' IN MODELLI MURINI

P. Senesi · 2015 · Università degli Studi di Milano (AIR) · DOI

Full title: STUDIO DELL'EFFETTO PREVENTIVO DELLA METFORMINA SUI DANNI ASSOCIATI ALLA SEDENTARIETA' IN MODELLI MURINI

Authors: P. Senesi

Year: 2015

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/260285

Thesis Meal Timing, Aging, and Metabolic Health.

Kessler, Katharina; Pivovarova-Ramich, Olga · 2019 · University of Cambridge · DOI

Full title: Meal Timing, Aging, and Metabolic Health.

Authors: Kessler, Katharina; Pivovarova-Ramich, Olga

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/292551

Thesis Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.

Cassidy, Liam D; Young, Andrew RJ; Young, Christopher NJ et al. · 2019 · University of Cambridge · DOI

Full title: Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.

Authors: Cassidy, Liam D; Young, Andrew RJ; Young, Christopher NJ; Soilleux, Elizabeth J; Fielder, Edward; Weigand, Bettina M; Lagnado, Anthony; Brais, Rebecca; Ktistakis, Nicholas T; Wiggins, Kimberley A; Pyrillou, Katerina; Clarke, Murray CH; Jurk, Diana; Passos, Joao F; Narita, Masashi

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/300207

Thesis The role of the tryptophan-NAD + pathway in a mouse model of severe malnutrition induced liver dysfunction.

Hu, Guanlan; Ling, Catriona; Chi, Lijun et al. · 2022 · University of Cambridge · DOI

Full title: The role of the tryptophan-NAD + pathway in a mouse model of severe malnutrition induced liver dysfunction.

Authors: Hu, Guanlan; Ling, Catriona; Chi, Lijun; Thind, Mehakpreet K; Furse, Samuel; Koulman, Albert; Swann, Jonathan R; Lee, Dorothy; Calon, Marjolein M; Bourdon, Celine; Versloot, Christian J; Bakker, Barbara M; Gonzales, Gerard Bryan; Kim, Peter K; Bandsma, Robert HJ

Year: 2022

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/344129

Thesis Of mice and men: opposing effects of nicotinamide riboside on skeletal muscle physiology at rest and during exercise.

Ferreira, Laís SS; De-Souza, Evandro A · 2021 · University of Cambridge · DOI

Full title: Of mice and men: opposing effects of nicotinamide riboside on skeletal muscle physiology at rest and during exercise.

Authors: Ferreira, Laís SS; De-Souza, Evandro A

Year: 2021

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/322629

Thesis Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects.

Strong, Randy; Miller, Richard A; Bogue, Molly et al. · 2020 · University of Cambridge · DOI

Full title: Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects.

Authors: Strong, Randy; Miller, Richard A; Bogue, Molly; Fernandez, Elizabeth; Javors, Martin A; Libert, Sergiy; Marinez, Paul Anthony; Murphy, Michael P; Musi, Nicolas; Nelson, James F; Petrascheck, Michael; Reifsnyder, Peter; Richardson, Arlan; Salmon, Adam B; Macchiarini, Francesca; Harrison, David E

Year: 2020

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/312679

Thesis Stärkung endogener Regenerationsmechanismen durch Modulation des mTOR-Signalnetzwerks

Hegner, Björn Gerrit · 2024 · Freie Universität Berlin (Refubium) · DOI

Full title: Stärkung endogener Regenerationsmechanismen durch Modulation des mTOR-Signalnetzwerks

Authors: Hegner, Björn Gerrit

Year: 2024

Venue: Freie Universität Berlin (Refubium)

DOI: https://refubium.fu-berlin.de/handle/fub188/44263

Thesis Pharmacology of aging: Drosophila as a tool to validate drug targets for healthy lifespan

Dos Santos, Eliano; Cocheme, Helena · 2024 · Imperial College London · DOI

Full title: Pharmacology of aging: Drosophila as a tool to validate drug targets for healthy lifespan

Authors: Dos Santos, Eliano; Cocheme, Helena

Year: 2024

Venue: Imperial College London

DOI: https://agingcelljournal.org/Archive/Volume2/20240034/

Thesis Evaluation of the effect of autophagy flux control by rapamycin and hydroxychloroquine in the senescent phenotype of hepatocytes and adipocytes in mouse model

Martins, Joilson de Oliveira · 2024 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Evaluation of the effect of autophagy flux control by rapamycin and hydroxychloroquine in the senescent phenotype of hepatocytes and adipocytes in mouse model

Authors: Martins, Joilson de Oliveira

Year: 2024

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://sbfte.org.br/wp-content/uploads/2024/10/Livro-2024_fn.pdf

Thesis Effects of nutritional status on mitochondrial Ca2+ handling

Menezes Filho, Sérgio Luiz de · 2019 · Universidade de São Paulo – BDTD · DOI

Full title: Effects of nutritional status on mitochondrial Ca2+ handling

Authors: Menezes Filho, Sérgio Luiz de

Year: 2019

Venue: Universidade de São Paulo – BDTD

DOI: http://www.teses.usp.br/teses/disponiveis/46/46131/tde-04072019-112540/

Thesis Ether Lipid Biosynthesis Promotes Lifespan Extension and Enables Diverse Prolongevity Paradigms

Cedillo, Lucydalila · 2022 · Harvard University - DASH · DOI

Full title: Ether Lipid Biosynthesis Promotes Lifespan Extension and Enables Diverse Prolongevity Paradigms

Authors: Cedillo, Lucydalila

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372071

Thesis Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Vermeij, W P; Dollé, M E T; Reiling, E et al. · 2016 · Utrecht University · DOI

Full title: Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Authors: Vermeij, W P; Dollé, M E T; Reiling, E; Jaarsma, D; Payan-Gomez, C; Bombardieri, C R; Wu, H; Roks, A J M; Botter, S M; van der Eerden, B C; Youssef, S A; Kuiper, R V; Nagarajah, B; van Oostrom, C T; Brandt, R M C; Barnhoorn, S; Imholz, S; Pennings, J L A; de Bruin, A; Gyenis, Á; Pothof, J; Vijg, J; van Steeg, H; Hoeijmakers, J H J

Year: 2016

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/346767

Thesis Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice

Müller, Christine B.; Zidek, Laura M; Ackermann, Tobias et al. · 2018 · Utrecht University · DOI

Full title: Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice

Authors: Müller, Christine B.; Zidek, Laura M; Ackermann, Tobias; de Jong, Tristan; Liu, Peng; Kliche, Verena; Zaini, Mohamad Amr; Kortman, Gertrud; Harkema, Liesbeth; Verbeek, Dineke S; Tuckermann, Jan P; von Maltzahn, Julia; de Bruin, Alain; Guryev, Victor; Wang, Zhao-Qi; Calkhoven, Cornelis F

Year: 2018

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/375292

Thesis Dietary Restriction: Standing Up for Sirtuins

Baur, J. A.; Chen, D.; Chini, E. N. et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Dietary Restriction: Standing Up for Sirtuins

Authors: Baur, J. A.; Chen, D.; Chini, E. N.; Chua, K.; Cohen, H. Y.; de Cabo, R.; Deng, C.; Dimmeler, S.; Gius, D.; Helfand, S. L.; Imai, S.-I.; Itoh, H.; Kadowaki, T.; Koya, D.; Leeuwenburgh, C.; McBurney, M.; Nabeshima, Y.-I.; Neri, C.; Oberdoerffer, P.; Pestell, R. G.; Rogina, B.; Sadoshima, J.; Sartorelli, V.; Serrano, M.; Sinclair, D. A.; Steegborn, C.; Tatar, M.; Tissenbaum, H. A.; Tong, Q.; Tsubota, K.; Vaquero, A.; Verdin, E.; Guarente, Leonard Pershing

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116434

Thesis It takes two to tango: NAD+ and sirtuins in aging/longevity control

Imai, Shin-ichiro; Guarente, Leonard Pershing · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: It takes two to tango: NAD+ and sirtuins in aging/longevity control

Authors: Imai, Shin-ichiro; Guarente, Leonard Pershing

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116435

Thesis NAD+ and sirtuins in aging and disease

Imai, Shin-ichiro; Guarente, Leonard Pershing · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: NAD+ and sirtuins in aging and disease

Authors: Imai, Shin-ichiro; Guarente, Leonard Pershing

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/106590

Thesis Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Imai, Shin-ichiro; Guarente, Leonard Pershing · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Authors: Imai, Shin-ichiro; Guarente, Leonard Pershing

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/106460

Thesis Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

Strong, Randy; Miller, Richard A.; Antebi, Adam et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

Authors: Strong, Randy; Miller, Richard A.; Antebi, Adam; Astle, Clinton M.; Bogue, Molly; Denzel, Martin S.; Fernandez, Elizabeth; Flurkey, Kevin; Hamilton, Karyn L.; Lamming, Dudley W.; Javors, Martin A.; de Magalhães, João Pedro; Martinez, Paul Anthony; McCord, Joe M.; Miller, Benjamin F.; Müller, Michael; Nelson, James F.; Ndukum, Juliet; Rainger, G. Ed.; Richardson, Arlan; Salmon, Adam B.; Simpkins, James W.; Steegenga, Wilma T.; Nadon, Nancy L.; Harrison, David E.; Sabatini, David

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/108183

Thesis mTOR Signaling in Growth, Metabolism, and Disease

Saxton, Robert Andrew; Sabatini, David · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: mTOR Signaling in Growth, Metabolism, and Disease

Authors: Saxton, Robert Andrew; Sabatini, David

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116766

Thesis NAD + supplementation rejuvenates aged gut adult stem cells

Igarashi, Masaki; Miura, Masaomi; Williams, Eric O et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: NAD + supplementation rejuvenates aged gut adult stem cells

Authors: Igarashi, Masaki; Miura, Masaomi; Williams, Eric O; Jaksch, Frank; Kadowaki, Takashi; Yamauchi, Toshimasa; Guarente, Leonard Pershing

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/125404

Thesis A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Graeff, Johannes; Kahn, Martin; Samiei, Alireza et al. · 2017 · Massachusetts Institute of Technology (MIT) · DOI

Full title: A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

Authors: Graeff, Johannes; Kahn, Martin; Samiei, Alireza; Gao, Jun; Ota, Kristie; Rei, Damien; Tsai, Li-Huei

Year: 2017

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/112704

Thesis Sirtuins, Aging, and Medicine

Guarente, Leonard Pershing · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Sirtuins, Aging, and Medicine

Authors: Guarente, Leonard Pershing

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/124934

Thesis Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

Freinkman, Elizaveta; Thomas, Craig J.; Gui, Dan Yi et al. · 2018 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

Authors: Freinkman, Elizaveta; Thomas, Craig J.; Gui, Dan Yi; Sullivan, Lucas Bryan; Luengo, Alba; Hosios, Aaron Marc; Bush, Lauren N.; Gitego, Nadege; Davidson, Shawn M; Vander Heiden, Matthew G.

Year: 2018

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/116918

Thesis Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging

Das, Abhirup; Huang, George X.; Bonkowski, Michael S. et al. · 2020 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging

Authors: Das, Abhirup; Huang, George X.; Bonkowski, Michael S.; Longchamp, Alban; Li, Catherine; Schultz, Michael B.; Kim, Lynn-Jee; Osborne, Brenna; Joshi, Sanket; Lu, Yuancheng; Treviño-Villarreal, Jose Humberto; Kang, Myung-Jin; Hung, Tzong-tyng; Lee, Brendan; Williams, Eric O; Igarashi, Masaki; Mitchell, James R.; Wu, Lindsay E.; Turner, Nigel; Arany, Zolt; Guarente, Leonard Pershing; Sinclair, David A.

Year: 2020

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/126072

Thesis The SirT3 Divining Rod Points to Oxidative Stress

Bell, Eric L.; Guarente, Leonard Pershing · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: The SirT3 Divining Rod Points to Oxidative Stress

Authors: Bell, Eric L.; Guarente, Leonard Pershing

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/84480

Thesis The [NAD[superscript +] over Sirtuin] Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Mouchiroud, Laurent; Houtkooper, Riekelt H.; Moullan, Norman et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: The [NAD[superscript +] over Sirtuin] Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Authors: Mouchiroud, Laurent; Houtkooper, Riekelt H.; Moullan, Norman; Katsyuba, Elena; Ryu, Dongryeol; Canto, Carles; Mottis, Adrienne; Jo, Young-Suk; Viswanathan, Mohan; Schoonjans, Kristina; Auwerx, Johan; Guarente, Leonard Pershing

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96399

Thesis Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Lamming, Dudley W.; Ye, Lan; Katajisto, Pekka et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Authors: Lamming, Dudley W.; Ye, Lan; Katajisto, Pekka; Goncalves, Marcus D.; Saitoh, Maki; Stevens, Deanna M.; Davis, James G.; Salmon, Adam B.; Richardson, Arlan; Ahima, Rexford S.; Guertin, David A.; Baur, Joseph A.; Sabatini, David

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/85837

Thesis Calorie restriction and sirtuins revisited

Guarente, Leonard Pershing · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Calorie restriction and sirtuins revisited

Authors: Guarente, Leonard Pershing

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/84509

Thesis Metabolic and Neuropsychiatric Effects of Calorie Restriction and Sirtuins

Libert, Sergiy V.; Guarente, Leonard Pershing · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Metabolic and Neuropsychiatric Effects of Calorie Restriction and Sirtuins

Authors: Libert, Sergiy V.; Guarente, Leonard Pershing

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/84495

Thesis Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

Lamming, Dudley W.; Mihaylova, Maria M.; Katajisto, Pekka et al. · 2014 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

Authors: Lamming, Dudley W.; Mihaylova, Maria M.; Katajisto, Pekka; Baar, Emma L.; Yilmaz, Omer; Hutchins, Amanda W.; Gultekin, Yetis; Gaither, Rachel P.; Sabatini, David M.

Year: 2014

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/89397

Thesis Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Lamming, Dudley W.; Ye, Lan; Astle, Clinton M. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Authors: Lamming, Dudley W.; Ye, Lan; Astle, Clinton M.; Baur, Joseph A.; Harrison, David E.; Sabatini, David

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96741

Thesis Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

Mercken, Evi M.; Crosby, Seth D.; Lamming, Dudley W. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

Authors: Mercken, Evi M.; Crosby, Seth D.; Lamming, Dudley W.; JeBailey, Lellean; Krzysik-Walker, Susan; Villareal, Dennis T.; Capri, Miriam; Franceschi, Claudio; Zhang, Yongqing; Becker, Kevin; de Cabo, Rafael; Fontana, Luigi; Sabatini, David

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96746

Thesis Effects of SIRT1 mutation or over-expression in astrocytes on metabolism and reproduction /

Choi, Irene Su Jeen · 2014 · University of California, San Diego (UCSD) · DOI

Full title: Effects of SIRT1 mutation or over-expression in astrocytes on metabolism and reproduction /

Authors: Choi, Irene Su Jeen

Year: 2014

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/2kp9f999

Thesis The Interaction of Aging, Caloric Restriction, and the Sulfur Assimilation pathway explored via Quantitative Time-lapse Flow Cytometry

Fellowes, Peter · 2014 · University of California, San Francisco (UCSF) · DOI

Full title: The Interaction of Aging, Caloric Restriction, and the Sulfur Assimilation pathway explored via Quantitative Time-lapse Flow Cytometry

Authors: Fellowes, Peter

Year: 2014

Venue: University of California, San Francisco (UCSF)

DOI: https://escholarship.org/uc/item/2gz8n8gm

Thesis Dissecting out the mechanisms to longevity through eating less

Mulvey, Lorna · 2017 · University of Glasgow · DOI

Full title: Dissecting out the mechanisms to longevity through eating less

Authors: Mulvey, Lorna

Year: 2017

Venue: University of Glasgow

DOI: https://theses.gla.ac.uk/8645/15/2017mulveyphd.pdf

Thesis Metabolic tracing of NAD+ precursors using strategically labelled isotopes of NMN

Kim, Lynn-Jee · 2020 · UNSW Sydney · DOI

Full title: Metabolic tracing of NAD+ precursors using strategically labelled isotopes of NMN

Authors: Kim, Lynn-Jee

Year: 2020

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/70443

Thesis Modulation of SIRT-1 as an anti-ageing target

Massudi, Hassina · 2016 · UNSW Sydney · DOI

Full title: Modulation of SIRT-1 as an anti-ageing target

Authors: Massudi, Hassina

Year: 2016

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/55950

Thesis Physiological Effects of Modulating Sirtuin 5 and Mitochondrial NAD+ Biosynthesis in Mammals

Bentley, Nicholas · 2018 · UNSW Sydney · DOI

Full title: Physiological Effects of Modulating Sirtuin 5 and Mitochondrial NAD+ Biosynthesis in Mammals

Authors: Bentley, Nicholas

Year: 2018

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/60258

Thesis The evidence basis of diving and hyperbaric medicine - a synthesis of the high level clinical evidence with meta-analysis

Bennett, Michael Heywood · 2006 · UNSW Sydney · DOI

Full title: The evidence basis of diving and hyperbaric medicine - a synthesis of the high level clinical evidence with meta-analysis

Authors: Bennett, Michael Heywood

Year: 2006

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/24243

Thesis Avaliação dos efeitos da administração de ribosídeo de nicotinamida sobre parâmetros biométricos, metabólicos, oxidativos e inflamatórios em ratos Wistar submetidos ao modelo de obesidade

Castro, Josimar Macedo de · 2020 · Universidade Federal do Rio Grande do Sul – LUME · DOI

Full title: Avaliação dos efeitos da administração de ribosídeo de nicotinamida sobre parâmetros biométricos, metabólicos, oxidativos e inflamatórios em ratos Wistar submetidos ao modelo de obesidade

Authors: Castro, Josimar Macedo de

Year: 2020

Venue: Universidade Federal do Rio Grande do Sul – LUME

DOI: http://hdl.handle.net/10183/215323

Thesis Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity.

Hahn, Oliver; Stubbs, Thomas M; Reik, Wolf et al. · 2019 · University of Cambridge · DOI

Full title: Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity.

Authors: Hahn, Oliver; Stubbs, Thomas M; Reik, Wolf; Grönke, Sebastian; Beyer, Andreas; Partridge, Linda

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/293698

Thesis Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells.

Neumann, Björn; Baror, Roey; Zhao, Chao et al. · 2019 · University of Cambridge · DOI

Full title: Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells.

Authors: Neumann, Björn; Baror, Roey; Zhao, Chao; Segel, Michael; Dietmann, Sabine; Rawji, Khalil S; Foerster, Sarah; McClain, Crystal R; Chalut, Kevin; van Wijngaarden, Peter; Franklin, Robin JM

Year: 2019

Venue: University of Cambridge

DOI: https://www.repository.cam.ac.uk/handle/1810/296382

Thesis DIET-SPECIFIC EPIGENETIC SIGNATURE REVEALED BY H3K4ME3 AND H3K27ME3 DATA ANALYSIS IN C57BL6 MICE

A. Russo · 2016 · Università degli Studi di Milano (AIR) · DOI

Full title: DIET-SPECIFIC EPIGENETIC SIGNATURE REVEALED BY H3K4ME3 AND H3K27ME3 DATA ANALYSIS IN C57BL6 MICE

Authors: A. Russo

Year: 2016

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/365343

Thesis TOWARDS LONGER LIVES: THE ETHICAL IMPLICATIONS OF LIFE EXTENSION BY CALORIE RESTRICTION AND CALORIE RESTRICTION MIMETICS

C. Wareham · 2013 · Università degli Studi di Milano (AIR) · DOI

Full title: TOWARDS LONGER LIVES: THE ETHICAL IMPLICATIONS OF LIFE EXTENSION BY CALORIE RESTRICTION AND CALORIE RESTRICTION MIMETICS

Authors: C. Wareham

Year: 2013

Venue: Università degli Studi di Milano (AIR)

DOI: http://hdl.handle.net/2434/218888

Thesis Longevity, aging, and caloric restriction : Clive Maine McCay and the construction of a multidisciplinary research program

Park, Hyung Wook · 2013 · Nanyang Technological University (NTU) · DOI

Full title: Longevity, aging, and caloric restriction : Clive Maine McCay and the construction of a multidisciplinary research program

Authors: Park, Hyung Wook

Year: 2013

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/96440

Thesis mTOR at the nexus of nutrition, growth, ageing and disease

Liu, Grace Y; Sabatini, David M · 2021 · Massachusetts Institute of Technology (MIT) · DOI

Full title: mTOR at the nexus of nutrition, growth, ageing and disease

Authors: Liu, Grace Y; Sabatini, David M

Year: 2021

Venue: Massachusetts Institute of Technology (MIT)

DOI: https://hdl.handle.net/1721.1/136262

Thesis Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Finley, Lydia W. S.; Lee, Jaewon; Souza, Amanda et al. · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Authors: Finley, Lydia W. S.; Lee, Jaewon; Souza, Amanda; Desquiret-Dumas, Valérie; Bullock, Kevin; Rowe, Glenn C.; Procaccio, Vincent; Clish, Clary; Arany, Zoltan; Haigis, Marcia C.

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/72529

Thesis Rapamycin Doses Sufficient to Extend Lifespan Do Not Compromise Muscle Mitochondrial Content or Endurance

Ye, Lan; Widlund, Anne L.; Sims, Carrie A. et al. · 2015 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Rapamycin Doses Sufficient to Extend Lifespan Do Not Compromise Muscle Mitochondrial Content or Endurance

Authors: Ye, Lan; Widlund, Anne L.; Sims, Carrie A.; Lamming, Dudley W.; Guan, Yuxia; Davis, James G.; Harrison, David E.; Vang, Ole; Baur, Joseph A.; Sabatini, David

Year: 2015

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/96763

Thesis The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Yi, L; Maier, AB; Tao, R et al. · 2023 · University of Melbourne · DOI

Full title: The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Authors: Yi, L; Maier, AB; Tao, R; Lin, Z; Vaidya, A; Pendse, S; Thasma, S; Andhalkar, N; Avhad, G; Kumbhar, V

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/334587

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Full title: us-2023285321-a1

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· 2023

Full title: us-2023355646-a1

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· 2023

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· 2023

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· 2024

Full title: us-2024000753-a1

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· 2023

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· 2024

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· 2024

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· 2012

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· 2012

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· 2012

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· 2012

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· 2012

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· 2011

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· 2013

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· 2012

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· 2013

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· 2013

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2014

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· 2016

Full title: us-9278090-b2

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· 2015

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· 2015

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· 2016

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· 2016

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· 2016

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· 2014

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· 2016

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· 2016

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· 2017

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· 2017

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· 2018

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· 2018

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· 2018

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· 2018

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· 2018

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· 2020

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· 2020

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· 2021

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· 2020

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· 2020

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· 2021

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· 2020

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2021

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2022

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· 2019

Full title: us-10314865-b2

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· 2020

Full title: us-10617744-b2

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2020

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· 2021

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· 2021

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· 2020

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· 2021

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· 2021

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· 2021

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Metadata only

Paper Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock.

Minteer, Christopher; Morselli, Marco; Meer, Margarita et al. · 2022 · Aging cell · DOI

Full title: Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock.

Authors: Minteer, Christopher; Morselli, Marco; Meer, Margarita; Cao, Jian; Higgins-Chen, Albert; Lang, Sabine M; Pellegrini, Matteo; Yan, Qin; Levine, Morgan E

Year: 2022

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13553

Paper Protein phosphatase 2A activators reverse age-related behavioral changes by targeting neural cell senescence.

Xing, Jun; Chen, Kehua; Gao, Shuaiyun et al. · 2023 · Aging cell · DOI

Full title: Protein phosphatase 2A activators reverse age-related behavioral changes by targeting neural cell senescence.

Authors: Xing, Jun; Chen, Kehua; Gao, Shuaiyun; Pousse, Mélanie; Ying, Yilin; Wang, Bo; Chen, Lianxiang; Wang, Cuicui; Wang, Lei; Hu, Weiguo; Lu, Yiming; Gilson, Eric; Ye, Jing

Year: 2023

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13780

Paper Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice.

Dungan, Cory M; Murach, Kevin A; Zdunek, Christopher J et al. · 2022 · Aging cell · DOI

Full title: Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice.

Authors: Dungan, Cory M; Murach, Kevin A; Zdunek, Christopher J; Tang, Zuo Jian; Nolt, Georgia L; Brightwell, Camille R; Hettinger, Zachary; Englund, Davis A; Liu, Zheng; Fry, Christopher S; Filareto, Antonio; Franti, Michael; Peterson, Charlotte A

Year: 2022

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13528

Paper Emerging rejuvenation strategies-Reducing the biological age.

Zhang, Bohan; Trapp, Alexandre; Kerepesi, Csaba et al. · 2022 · Aging cell · DOI

Full title: Emerging rejuvenation strategies-Reducing the biological age.

Authors: Zhang, Bohan; Trapp, Alexandre; Kerepesi, Csaba; Gladyshev, Vadim N

Year: 2022

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13538

Paper Generalized low levels of serum N‐glycans associate with better health status

Jiteng Fan; Jichen Sha; Shuwai Chang et al. · 2023 · Aging Cell · DOI

Full title: Generalized low levels of serum N‐glycans associate with better health status

Authors: Jiteng Fan; Jichen Sha; Shuwai Chang; Huijuan Zhao; Xiaoyun Niu; Yong Gu; J. Gu; S. Ren

Year: 2023

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13855

Paper Chromatin‐transcription interface: The secret of eternal youth?

Izquierdo, José M. · 2023 · Aging Cell · DOI

Full title: Chromatin‐transcription interface: The secret of eternal youth?

Authors: Izquierdo, José M.

Year: 2023

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13927

Paper Intestinal stem cell aging at single-cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics.

Choi, Jiahn; Houston, Michele; Wang, Ruixuan et al. · 2023 · Aging cell · DOI

Full title: Intestinal stem cell aging at single-cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics.

Authors: Choi, Jiahn; Houston, Michele; Wang, Ruixuan; Ye, Kenny; Li, Wenge; Zhang, Xusheng; Huffman, Derek M; Augenlicht, Leonard H

Year: 2023

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13802

Paper Exercise reduces circulating biomarkers of cellular senescence in humans.

Englund, Davis A; Sakamoto, Ayumi E; Fritsche, Chad M et al. · 2021 · Aging cell · DOI

Full title: Exercise reduces circulating biomarkers of cellular senescence in humans.

Authors: Englund, Davis A; Sakamoto, Ayumi E; Fritsche, Chad M; Heeren, Amanda A; Zhang, Xu; Kotajarvi, Brian R; Lecy, Denise R; Yousefzadeh, Matthew J; Schafer, Marissa J; White, Thomas A; Atkinson, Elizabeth J; LeBrasseur, Nathan K

Year: 2021

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13415

Paper Youthful and age-related matreotypes predict drugs promoting longevity.

Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X et al. · 2021 · Aging cell · DOI

Full title: Youthful and age-related matreotypes predict drugs promoting longevity.

Authors: Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X; Dakhovnik, Alexander; Wandrey, Franziska; Mozharovskyi, Pavlo; Zülli, Fred; Ewald, Collin Y

Year: 2021

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13441

Paper Age‐dependent nuclear lipid droplet deposition is a cellular hallmark of aging in Caenorhabditis elegans

Palikaras, Konstantinos; Mari, Meropi; Ploumi, Christina et al. · 2023 · Aging Cell · DOI

Full title: Age‐dependent nuclear lipid droplet deposition is a cellular hallmark of aging in Caenorhabditis elegans

Authors: Palikaras, Konstantinos; Mari, Meropi; Ploumi, Christina; Princz, Andrea; Filippidis, George; Tavernarakis, Nektarios

Year: 2023

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13788

Paper Effect of peripheral cellular senescence on brain aging and cognitive decline.

Budamagunta, Vivekananda; Kumar, Ashok; Rani, Asha et al. · 2023 · Aging cell · DOI

Full title: Effect of peripheral cellular senescence on brain aging and cognitive decline.

Authors: Budamagunta, Vivekananda; Kumar, Ashok; Rani, Asha; Bean, Linda; Manohar-Sindhu, Sahana; Yang, Yang; Zhou, Daohong; Foster, Thomas C

Year: 2023

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.13817

Paper Cytochrome b5 reductase 3 overexpression and dietary nicotinamide riboside supplementation promote distinctive mitochondrial alterations in distal convoluted tubules of mouse kidneys during aging.

Pérez-Rodríguez, M; García-Verdugo, A; Sánchez-Mendoza, L M et al. · 2024 · Aging cell · DOI

Full title: Cytochrome b5 reductase 3 overexpression and dietary nicotinamide riboside supplementation promote distinctive mitochondrial alterations in distal convoluted tubules of mouse kidneys during aging.

Authors: Pérez-Rodríguez, M; García-Verdugo, A; Sánchez-Mendoza, L M; Muñoz-Martín, A; Bolaños, N; Pérez-Sánchez, C; Moreno, J A; Burón, M I; de Cabo, R; González-Reyes, J A; Villalba, J M

Year: 2024

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.14273

Paper Translatability of life-extending pharmacological treatments between different species.

Burdusel, Daiana; Coman, Cristin; Ancuta, Diana-Larisa et al. · 2024 · Aging cell · DOI

Full title: Translatability of life-extending pharmacological treatments between different species.

Authors: Burdusel, Daiana; Coman, Cristin; Ancuta, Diana-Larisa; Hermann, Dirk M; Doeppner, Thorsten R; Gresita, Andrei; Popa-Wagner, Aurel

Year: 2024

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.14208

Paper U‐shaped association between sleep duration and biological aging: Evidence from the UK Biobank study

Wang, Xuanyang; Yan, Xuemin; Li, Mengdi et al. · 2024 · Aging Cell · DOI

Full title: U‐shaped association between sleep duration and biological aging: Evidence from the UK Biobank study

Authors: Wang, Xuanyang; Yan, Xuemin; Li, Mengdi; Cheng, Licheng; Qi, Xiang; Zhang, Jiafan; Pan, Sijia; Xu, Xiaoqing; Wei, Wei; Li, Ying

Year: 2024

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.14159

Paper Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Zhu, Man; Ma, Meng; Luo, Lunan et al. · 2025 · Aging Cell · DOI

Full title: Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Authors: Zhu, Man; Ma, Meng; Luo, Lunan; Li, Feiyang; Zheng, Jiashun; Pan, Yan; Yang, Lu; Xiao, Ying; Wang, Ziyan; Xian, Bo; Zheng, Yi; Li, Hao; Yang, Jing

Year: 2025

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.70010

Paper Senolytic treatment attenuates immune cell infiltration without improving IAV outcomes in aged mice.

Luna, Adrian; Chou, Kai-Neng; Wragg, Kathleen M et al. · 2025 · Aging cell · DOI

Full title: Senolytic treatment attenuates immune cell infiltration without improving IAV outcomes in aged mice.

Authors: Luna, Adrian; Chou, Kai-Neng; Wragg, Kathleen M; Worley, Matthew J; Paruchuri, Nikhil; Zhou, Xiaofeng; Blin, Muriel G; Moore, Bethany B; Salmon, Morgan; Goldstein, Daniel R; Deng, Jane C

Year: 2025

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.14437

Paper AI-Driven Identification of Exceptionally Efficacious Polypharmacological Compounds That Extend the Lifespan of Caenorhabditis elegans.

Avchaciov, Konstantin; Clay, Khalyd J; Denisov, Kirill A et al. · 2025 · Aging cell · DOI

Full title: AI-Driven Identification of Exceptionally Efficacious Polypharmacological Compounds That Extend the Lifespan of Caenorhabditis elegans.

Authors: Avchaciov, Konstantin; Clay, Khalyd J; Denisov, Kirill A; Burmistrova, Olga; Petrascheck, Michael; Fedichev, Peter O

Year: 2025

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.70060

Paper Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.

Zhang, Lei; Pitcher, Louise E; Prahalad, Vaishali et al. · 2023 · The FEBS journal · DOI

Full title: Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.

Authors: Zhang, Lei; Pitcher, Louise E; Prahalad, Vaishali; Niedernhofer, Laura J; Robbins, Paul D

Year: 2023

Venue: The FEBS journal

DOI: https://doi.org/10.1111/febs.16350

Paper Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

Aaron P. Havas; Adarsh Rajesh; Xue Lei et al. · 2025 · bioRxiv · DOI

Full title: Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

Authors: Aaron P. Havas; Adarsh Rajesh; Xue Lei; Jessica Proulx; Karl N. Miller; Adam Field; Andrew Davis; M. Teneche; Armin Gandhi; P. Adams

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.07.25.666837

Paper Effect of life span prolonging drugs (geroprotectors) on spontaneous and induced carcinogenesis.

Anisimov, V N · 1994 · Annals of the New York Academy of Sciences · DOI

Full title: Effect of life span prolonging drugs (geroprotectors) on spontaneous and induced carcinogenesis.

Authors: Anisimov, V N

Year: 1994

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1111/j.1749-6632.1994.tb12083.x

Paper Regulation of inflammation as an anti‐aging intervention

J. Neves; Pedro Sousa‐Victor · 2020 · The FEBS Journal · DOI

Full title: Regulation of inflammation as an anti‐aging intervention

Authors: J. Neves; Pedro Sousa‐Victor

Year: 2020

Venue: The FEBS Journal

DOI: https://doi.org/10.1111/febs.15061

Paper Recent advances in biomarkers for senescence: Bridging basic research to clinic.

Fukumoto, Takeshi; Shimosawa, Tatsuo; Yakabe, Mitsutaka et al. · 2025 · Geriatrics & gerontology international · DOI

Full title: Recent advances in biomarkers for senescence: Bridging basic research to clinic.

Authors: Fukumoto, Takeshi; Shimosawa, Tatsuo; Yakabe, Mitsutaka; Yoshida, Shota; Yoshida, Yohko

Year: 2025

Venue: Geriatrics & gerontology international

DOI: https://doi.org/10.1111/ggi.15054

Paper Age-related increase of reactive oxygen generation in the brains of mammals and birds: is reactive oxygen a signaling molecule to determine the aging process and life span?

Sasaki, Toru; Unno, Keiko; Tahara, Shoichi et al. · 2010 · Geriatrics & gerontology international · DOI

Full title: Age-related increase of reactive oxygen generation in the brains of mammals and birds: is reactive oxygen a signaling molecule to determine the aging process and life span?

Authors: Sasaki, Toru; Unno, Keiko; Tahara, Shoichi; Kaneko, Takao

Year: 2010

Venue: Geriatrics & gerontology international

DOI: https://doi.org/10.1111/j.1447-0594.2010.00601.x

Paper An aging Interventions Testing Program: study design and interim report

Miller, Richard A.; Strong, Randy; Astle, Clinton M. et al. · 2007 · Aging Cell · DOI

Full title: An aging Interventions Testing Program: study design and interim report

Authors: Miller, Richard A.; Strong, Randy; Astle, Clinton M.; Floyd, Robert A.; Flurkey, Kevin; Hensley, Kenneth; Javors, Martin A.; Leeuwenburgh, Christiaan; Nelson, James F.; Ongini, Ennio; Nadon, Nancy L.; Warner, Huber R.; Strong, Randy

Year: 2007

Venue: Aging Cell

DOI: https://doi.org/10.1111/j.1474-9726.2007.00311.x

Paper Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

Strong, Randy; Miller, Richard A.; Astle, Clinton M. et al. · 2008 · Aging Cell · DOI

Full title: Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

Authors: Strong, Randy; Miller, Richard A.; Astle, Clinton M.; Floyd, Robert A.; Flurkey, Kevin; Hensley, Kenneth; Javors, Martin A.; Leeuwenburgh, Christiaan; Nelson, James F.; Ongini, Ennio; Nadon, Nancy L.; Warner, Huber R.; Strong, Randy

Year: 2008

Venue: Aging Cell

DOI: https://doi.org/10.1111/j.1474-9726.2008.00414.x

Paper Plant-derived nanovesicles offer a promising avenue for anti-aging interventions.

Meng, Yiming; Sun, Jing; Yu, Tao et al. · 2024 · Physiologia plantarum · DOI

Full title: Plant-derived nanovesicles offer a promising avenue for anti-aging interventions.

Authors: Meng, Yiming; Sun, Jing; Yu, Tao; Piao, Haozhe

Year: 2024

Venue: Physiologia plantarum

DOI: https://doi.org/10.1111/ppl.14283

Paper Mortality shifts in Caenorhabditis elegans: remembrance of conditions past.

Wu, Deqing; Rea, Shane L; Cypser, James R et al. · 2009 · Aging cell · DOI

Full title: Mortality shifts in Caenorhabditis elegans: remembrance of conditions past.

Authors: Wu, Deqing; Rea, Shane L; Cypser, James R; Johnson, Thomas E

Year: 2009

Venue: Aging cell

DOI: https://doi.org/10.1111/j.1474-9726.2009.00523.x

Paper Challenges in anti-aging medicine-trends in biomarker discovery and therapeutic interventions for a healthy lifespan.

Popescu, Iuliana; Deelen, Joris; Illario, Maddalena et al. · 2023 · Journal of cellular and molecular medicine · DOI

Full title: Challenges in anti-aging medicine-trends in biomarker discovery and therapeutic interventions for a healthy lifespan.

Authors: Popescu, Iuliana; Deelen, Joris; Illario, Maddalena; Adams, Jan

Year: 2023

Venue: Journal of cellular and molecular medicine

DOI: https://doi.org/10.1111/jcmm.17912

Paper Senotherapy preserves resilience in aging.

Mikawa, Takumi; Yoshida, Kazumichi; Kondoh, Hiroshi · 2024 · Geriatrics & gerontology international · DOI

Full title: Senotherapy preserves resilience in aging.

Authors: Mikawa, Takumi; Yoshida, Kazumichi; Kondoh, Hiroshi

Year: 2024

Venue: Geriatrics & gerontology international

DOI: https://doi.org/10.1111/ggi.14949

Paper Methionine restriction and life-span control.

Lee, Byung Cheon; Kaya, Alaattin; Gladyshev, Vadim N · 2016 · Annals of the New York Academy of Sciences · DOI

Full title: Methionine restriction and life-span control.

Authors: Lee, Byung Cheon; Kaya, Alaattin; Gladyshev, Vadim N

Year: 2016

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1111/nyas.12973

Paper A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases.

Alharbi, Khalid Saad; Afzal, Obaid; Altamimi, Abdulmalik Saleh Alfawaz et al. · 2022 · Journal of food biochemistry · DOI

Full title: A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases.

Authors: Alharbi, Khalid Saad; Afzal, Obaid; Altamimi, Abdulmalik Saleh Alfawaz; Almalki, Waleed Hassan; Kazmi, Imran; Al-Abbasi, Fahad A; Alzarea, Sami I; Makeen, Hafiz A; Albratty, Mohammed

Year: 2022

Venue: Journal of food biochemistry

DOI: https://doi.org/10.1111/jfbc.14471

Paper Focus on senescence: Clinical significance and practical applications.

Boccardi, Virginia; Orr, Miranda Ethel; Polidori, M Cristina et al. · 2024 · Journal of internal medicine · DOI

Full title: Focus on senescence: Clinical significance and practical applications.

Authors: Boccardi, Virginia; Orr, Miranda Ethel; Polidori, M Cristina; Ruggiero, Carmelinda; Mecocci, Patrizia

Year: 2024

Venue: Journal of internal medicine

DOI: https://doi.org/10.1111/joim.13775

Paper Position Statement on Human Aging

Olshansky, S. Jay; Hayflick, Leonard; Carnes, Bruce A. · 2002 · Science of Aging Knowledge Environment · DOI

Full title: Position Statement on Human Aging

Authors: Olshansky, S. Jay; Hayflick, Leonard; Carnes, Bruce A.

Year: 2002

Venue: Science of Aging Knowledge Environment

DOI: https://doi.org/10.1126/sageke.2002.24.pe9

Paper The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion

W. Delabie; W. Maes; R. Devloo et al. · 2019 · Transfusion · DOI

Full title: The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion

Authors: W. Delabie; W. Maes; R. Devloo; Michelle Van den Hauwe; K. Vanhoorelbeke; V. Compernolle; H. Feys

Year: 2019

Venue: Transfusion

DOI: https://doi.org/10.1111/trf.15556

Paper Metabolic regulation of behavior by the intestinal enzyme FMO-2.

Kitto, Elizabeth S; Beydoun, Safa; Henry, Ella et al. · 2025 · Science advances · DOI

Full title: Metabolic regulation of behavior by the intestinal enzyme FMO-2.

Authors: Kitto, Elizabeth S; Beydoun, Safa; Henry, Ella; Schaller, Megan L; Bhandari, Mira; Easow, Sarah A; Tuckowski, Angela M; Howington, Marshall B; Bhat, Ajay; Sridhar, Aditya; Chung, Eugene; Evans, Charles R; Leiser, Scott F

Year: 2025

Venue: Science advances

DOI: https://doi.org/10.1126/sciadv.adx3018

Paper Manipulating Cellular Energetics to Slow Aging of Tissues and Organs

S. Sokolov; F. Severin · 2020 · Biochemistry (Moscow) · DOI

Full title: Manipulating Cellular Energetics to Slow Aging of Tissues and Organs

Authors: S. Sokolov; F. Severin

Year: 2020

Venue: Biochemistry (Moscow)

DOI: https://doi.org/10.1134/s0006297920060024

Paper Geroscience: A Translational Review.

Kritchevsky, Stephen B; Cummings, Steven R · 2025 · JAMA · DOI

Full title: Geroscience: A Translational Review.

Authors: Kritchevsky, Stephen B; Cummings, Steven R

Year: 2025

Venue: JAMA

DOI: https://doi.org/10.1001/jama.2025.11289

Paper Metabolic reprogramming: a bridge between aging and tumorigenesis

Drápela, Stanislav; Ilter, Didem; Gomes, Ana P. · 2022 · Molecular Oncology · DOI

Full title: Metabolic reprogramming: a bridge between aging and tumorigenesis

Authors: Drápela, Stanislav; Ilter, Didem; Gomes, Ana P.

Year: 2022

Venue: Molecular Oncology

DOI: https://doi.org/10.1002/1878-0261.13261

Paper Small Molecule from Natural Phytochemical Mimics Dietary Restriction by Modulating FoxO3a and Metabolic Reprogramming

Juewon Kim; Shinhae Lee; Miook Cho et al. · 2020 · Advanced Biosystems · DOI

Full title: Small Molecule from Natural Phytochemical Mimics Dietary Restriction by Modulating FoxO3a and Metabolic Reprogramming

Authors: Juewon Kim; Shinhae Lee; Miook Cho; Jee-Young Lee; Dong-Hwa Choi; Hye-Yeon Lee; S. Cho; Kyung‐Jin Min; Y. Suh

Year: 2020

Venue: Advanced Biosystems

DOI: https://doi.org/10.1002/adbi.201900248

Paper A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan.

Wang, Jiqun; Liu, Wenwen; Huang, Yunyuan et al. · 2024 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan.

Authors: Wang, Jiqun; Liu, Wenwen; Huang, Yunyuan; Wang, Guangwei; Guo, Xiaobo; Shi, Donglei; Sun, Tianyue; Xiao, Chaojiang; Zhang, Chao; Jiang, Bei; Guo, Yuan; Li, Jian

Year: 2024

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202401862

Paper Biomarkers of Cellular Senescence and Aging: Current State-of-the-Art, Challenges and Future Perspectives.

Muthamil, Subramanian; Kim, Hyun-Yong; Jang, Hyun-Jun et al. · 2024 · Advanced biology · DOI

Full title: Biomarkers of Cellular Senescence and Aging: Current State-of-the-Art, Challenges and Future Perspectives.

Authors: Muthamil, Subramanian; Kim, Hyun-Yong; Jang, Hyun-Jun; Lyu, Ji-Hyo; Shin, Ung Cheol; Go, Younghoon; Park, Seong-Hoon; Lee, Hee Gu; Park, Jun Hong

Year: 2024

Venue: Advanced biology

DOI: https://doi.org/10.1002/adbi.202400079

Paper Insulin as an Accelerator and Brake of Aging: From Molecular Landscape to Clinical Interventions.

Chen, Shi-Cheng; Sun, Xiao-Dong; Zhang, Yuan-Yuan · 2025 · Comprehensive Physiology · DOI

Full title: Insulin as an Accelerator and Brake of Aging: From Molecular Landscape to Clinical Interventions.

Authors: Chen, Shi-Cheng; Sun, Xiao-Dong; Zhang, Yuan-Yuan

Year: 2025

Venue: Comprehensive Physiology

DOI: https://doi.org/10.1002/cph4.70079

Paper The biology of frailty in humans and animals: Understanding frailty and promoting translation

Bisset, Elise S.; Howlett, Susan E. · 2019 · Aging Medicine · DOI

Full title: The biology of frailty in humans and animals: Understanding frailty and promoting translation

Authors: Bisset, Elise S.; Howlett, Susan E.

Year: 2019

Venue: Aging Medicine

DOI: https://doi.org/10.1002/agm2.12058

Paper Integrative Omics Reveal Female-Specific Benefits of p16+ Cell Clearance in Aging Mice.

Lin, Yao; Wang, Boshi; Huang, Mengling et al. · 2026 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · DOI

Full title: Integrative Omics Reveal Female-Specific Benefits of p16+ Cell Clearance in Aging Mice.

Authors: Lin, Yao; Wang, Boshi; Huang, Mengling; Wolters, Justina C; Demaria, Marco

Year: 2026

Venue: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

DOI: https://doi.org/10.1002/advs.202509444

Paper Resveratrol and rapamycin: are they anti-aging drugs?

Kaeberlein, Matt · 2010 · BioEssays : news and reviews in molecular, cellular and developmental biology · DOI

Full title: Resveratrol and rapamycin: are they anti-aging drugs?

Authors: Kaeberlein, Matt

Year: 2010

Venue: BioEssays : news and reviews in molecular, cellular and developmental biology

DOI: https://doi.org/10.1002/bies.200900171

Paper Effect of geroprotectors on metabolic health and cognitive function in a mouse model of Alzheimer’s disease

R. Babygirija; Michelle Sonsella; Victoria Flores et al. · 2021 · Alzheimer's & Dementia · DOI

Full title: Effect of geroprotectors on metabolic health and cognitive function in a mouse model of Alzheimer’s disease

Authors: R. Babygirija; Michelle Sonsella; Victoria Flores; Michaela E. Murphy; Cara L. Green; Heidi H Pak; Nicole E. Richardson; D. Lamming

Year: 2021

Venue: Alzheimer's & Dementia

DOI: https://doi.org/10.1002/alz.053224

Paper Nurturing longevity through natural compounds: Where do we stand, and where do we go?

Monika N. Todorova; Martina S. Savova; L. Mihaylova et al. · 2024 · Food Frontiers · DOI

Full title: Nurturing longevity through natural compounds: Where do we stand, and where do we go?

Authors: Monika N. Todorova; Martina S. Savova; L. Mihaylova; M. Georgiev

Year: 2024

Venue: Food Frontiers

DOI: https://doi.org/10.1002/fft2.350

Paper How can aging be reversed? Exploring rejuvenation from a damage‐based perspective

Zhang, Bohan; Gladyshev, Vadim N. · 2020 · Advanced Genetics · DOI

Full title: How can aging be reversed? Exploring rejuvenation from a damage‐based perspective

Authors: Zhang, Bohan; Gladyshev, Vadim N.

Year: 2020

Venue: Advanced Genetics

DOI: https://doi.org/10.1002/ggn2.10025

Paper Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

Arc‐Chagnaud, Coralie; Salvador‐Pascual, Andrea; García-Domínguez, Esther et al. · 2021 · Journal of Cachexia Sarcopenia and Muscle · DOI

Full title: Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

Authors: Arc‐Chagnaud, Coralie; Salvador‐Pascual, Andrea; García-Domínguez, Esther; Olaso‐González, Gloria; Correas, Ángela G.; Serna, Eva; Brioche, Thomas; Chopard, Angèle; Fernández-Marcos, Pablo J.; Serrano, Manuel; Serrano, Antonio L.; Muñoz‐Cánoves, Pura; Sebastiá, Vicente; Viña, José; Gómez‐Cabrera, Mari Carmen

Year: 2021

Venue: Journal of Cachexia Sarcopenia and Muscle

DOI: https://doi.org/10.1002/jcsm.12792

Paper Aging mechanisms—A perspective mostly from Drosophila

Tsurumi, Amy; Li, Willis X. · 2020 · Advanced Genetics · DOI

Full title: Aging mechanisms—A perspective mostly from Drosophila

Authors: Tsurumi, Amy; Li, Willis X.

Year: 2020

Venue: Advanced Genetics

DOI: https://doi.org/10.1002/ggn2.10026

Paper Protein Turnover in Aging and Longevity

Basisty, Nathan; Meyer, Jesse G.; Schilling, Birgit · 2018 · PROTEOMICS · DOI

Full title: Protein Turnover in Aging and Longevity

Authors: Basisty, Nathan; Meyer, Jesse G.; Schilling, Birgit

Year: 2018

Venue: PROTEOMICS

DOI: https://doi.org/10.1002/pmic.201700108

Paper Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention.

C. Lima; C. Pereira‐Wilson; Suresh I. S. Rattan · 2011 · Molecular Nutrition & Food Research · DOI

Full title: Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention.

Authors: C. Lima; C. Pereira‐Wilson; Suresh I. S. Rattan

Year: 2011

Venue: Molecular Nutrition & Food Research

DOI: https://doi.org/10.1002/mnfr.201000221

Paper The Aging Metabolome-Biomarkers to Hub Metabolites.

Sharma, Rishi; Ramanathan, Arvind · 2020 · Proteomics · DOI

Full title: The Aging Metabolome-Biomarkers to Hub Metabolites.

Authors: Sharma, Rishi; Ramanathan, Arvind

Year: 2020

Venue: Proteomics

DOI: https://doi.org/10.1002/pmic.201800407

Paper Obesity, Senescence, and Senolytics.

Chaib, Selim; Tchkonia, Tamara; Kirkland, James L · 2022 · Handbook of experimental pharmacology · DOI

Full title: Obesity, Senescence, and Senolytics.

Authors: Chaib, Selim; Tchkonia, Tamara; Kirkland, James L

Year: 2022

Venue: Handbook of experimental pharmacology

DOI: https://doi.org/10.1007/164_2021_555

Paper Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

Chen, Ruiye; Wang, Yueye; Zhang, Shiran et al. · 2023 · MedComm – Future Medicine · DOI

Full title: Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

Authors: Chen, Ruiye; Wang, Yueye; Zhang, Shiran; Bulloch, Gabriella; Zhang, Junyao; Liao, Huan; Shang, Xianwen; Clark, Malcolm; Peng, Qingsheng; Ge, Zongyuan; Cheng, Ching‐Yu; Gao, Yuanxu; He, Mingguang; Zhu, Zhuoting

Year: 2023

Venue: MedComm – Future Medicine

DOI: https://doi.org/10.1002/mef2.50

Paper Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells

Huang, Tongling; Liu, Renzhong; Fu, Xuekun et al. · 2016 · Stem Cells · DOI

Full title: Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells

Authors: Huang, Tongling; Liu, Renzhong; Fu, Xuekun; Yao, Dongsheng; Yang, Meng; Liu, Qingli; Lu, William W.; Wu, Chuanyue; Guan, Min

Year: 2016

Venue: Stem Cells

DOI: https://doi.org/10.1002/stem.2470

Paper Aging: Mechanisms, Measures, and Interventions

Chung, M.C.M.; Kennedy, Brian K. · 2020 · PROTEOMICS · DOI

Full title: Aging: Mechanisms, Measures, and Interventions

Authors: Chung, M.C.M.; Kennedy, Brian K.

Year: 2020

Venue: PROTEOMICS

DOI: https://doi.org/10.1002/pmic.201800336

Paper Determination of proteasomal activities.

Lima, Cristovao F; Rattan, Suresh I S · 2010 · Methods in molecular biology (Clifton, N.J.) · DOI

Full title: Determination of proteasomal activities.

Authors: Lima, Cristovao F; Rattan, Suresh I S

Year: 2010

Venue: Methods in molecular biology (Clifton, N.J.)

DOI: https://doi.org/10.1007/978-1-60761-756-3_12

Paper A Binary siRNA-Loaded Tetrahedral DNA Nanobox for Synergetic Anti-Aging Therapy.

Ziqi Yue; Yichen Yang; Lulingxiao Nie et al. · 2024 · Small · DOI

Full title: A Binary siRNA-Loaded Tetrahedral DNA Nanobox for Synergetic Anti-Aging Therapy.

Authors: Ziqi Yue; Yichen Yang; Lulingxiao Nie; Yuezhang Sun; Qi Wang; Yunfeng Lin; Yang Gao; Xiaoxiao Cai

Year: 2024

Venue: Small

DOI: https://doi.org/10.1002/smll.202408323

Paper Aging Biomarkers and Novel Targets for Anti-Aging Interventions.

Xu, Kang; Guo, Yannan; Li, Zhongchi et al. · 2019 · Advances in experimental medicine and biology · DOI

Full title: Aging Biomarkers and Novel Targets for Anti-Aging Interventions.

Authors: Xu, Kang; Guo, Yannan; Li, Zhongchi; Wang, Zhao

Year: 2019

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-030-25650-0_3

Paper The Use of Metformin to Increase the Human Healthspan.

V. Piskovatska; K. Storey; A. Vaiserman et al. · 2020 · Advances in Experimental Medicine and Biology · DOI

Full title: The Use of Metformin to Increase the Human Healthspan.

Authors: V. Piskovatska; K. Storey; A. Vaiserman; O. Lushchak

Year: 2020

Venue: Advances in Experimental Medicine and Biology

DOI: https://doi.org/10.1007/978-3-030-42667-5_13

Paper Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence.

Lushchak, Oleh; Piskovatska, Veronika; Strilbytska, Olha et al. · 2021 · Advances in experimental medicine and biology · DOI

Full title: Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence.

Authors: Lushchak, Oleh; Piskovatska, Veronika; Strilbytska, Olha; Kindrat, Iryna; Stefanyshyn, Nadya; Koliada, Alexander; Bubalo, Volodymyr; Storey, Kenneth B; Vaiserman, Alexander

Year: 2021

Venue: Advances in experimental medicine and biology

DOI: https://doi.org/10.1007/978-3-030-55035-6_11

Paper Intermittent Fasting as an Anti-Aging Strategy

Bhoumik, Sukanya; Yadawa, Arun Kumar; Srivastava, Parisha et al. · 2023 · DOI

Full title: Intermittent Fasting as an Anti-Aging Strategy

Authors: Bhoumik, Sukanya; Yadawa, Arun Kumar; Srivastava, Parisha; Rizvi, Syed Ibrahim

Year: 2023

DOI: https://doi.org/10.1007/978-981-19-7443-4_10

Paper Gerosuppressive and Senolytic Nutrients

J. Nehlin · 2021 · Healthy Ageing and Longevity · DOI

Full title: Gerosuppressive and Senolytic Nutrients

Authors: J. Nehlin

Year: 2021

Venue: Healthy Ageing and Longevity

DOI: https://doi.org/10.1007/978-3-030-83017-5_22

Paper AMPK as a Pro-longevity Target.

Burkewitz, Kristopher; Weir, Heather J M; Mair, William B · 2016 · Experientia supplementum (2012) · DOI

Full title: AMPK as a Pro-longevity Target.

Authors: Burkewitz, Kristopher; Weir, Heather J M; Mair, William B

Year: 2016

Venue: Experientia supplementum (2012)

DOI: https://doi.org/10.1007/978-3-319-43589-3_10

Paper Intermittent Fasting-Dietary Restriction as a Geroprotector

G. Kaur; T. Kaur; Anuradha Sharma et al. · 2018 · DOI

Full title: Intermittent Fasting-Dietary Restriction as a Geroprotector

Authors: G. Kaur; T. Kaur; Anuradha Sharma; Shaffi Manchanda; Harpal Singh; Shikha Kalotra; Payal Bajaj

Year: 2018

DOI: https://doi.org/10.1007/978-981-13-1699-9_13

Paper Unlocking the Potential of Senolytic Compounds: Advancements, Opportunities, and Challenges in Ageing-Related Research.

Gomez, Lilian Sales; Jurk, Diana · 2024 · Sub-cellular biochemistry · DOI

Full title: Unlocking the Potential of Senolytic Compounds: Advancements, Opportunities, and Challenges in Ageing-Related Research.

Authors: Gomez, Lilian Sales; Jurk, Diana

Year: 2024

Venue: Sub-cellular biochemistry

DOI: https://doi.org/10.1007/978-3-031-66768-8_5

Paper Algorithmic support of a testing unit for screening geroprotectors and geropromotors

P. S. Kudryavtsev; L. Y. Prokhorov; E. V. Khirova et al. · 1997 · DOI

Full title: Algorithmic support of a testing unit for screening geroprotectors and geropromotors

Authors: P. S. Kudryavtsev; L. Y. Prokhorov; E. V. Khirova; A. Khokhlov

Year: 1997

DOI: https://doi.org/10.1007/bf02369021

Paper Melatonin as a geroprotector: Experiments withDrosophila melanogaster

D. M. Izmaĭlov; L. K. Obukhova · 1999 · Bulletin of experimental biology and medicine · DOI

Full title: Melatonin as a geroprotector: Experiments withDrosophila melanogaster

Authors: D. M. Izmaĭlov; L. K. Obukhova

Year: 1999

Venue: Bulletin of experimental biology and medicine

DOI: https://doi.org/10.1007/bf02433110

Paper [Skin aging-cellular senescence : What is the future?].

Scharffetter-Kochanek, Karin; Wang, Yongfang; Makrantonaki, Evgenia et al. · 2023 · Dermatologie (Heidelberg, Germany) · DOI

Full title: [Skin aging-cellular senescence : What is the future?].

Authors: Scharffetter-Kochanek, Karin; Wang, Yongfang; Makrantonaki, Evgenia; Crisan, Diana; Wlaschek, Meinhard; Geiger, Hartmut; Maity, Pallab

Year: 2023

Venue: Dermatologie (Heidelberg, Germany)

DOI: https://doi.org/10.1007/s00105-023-05201-x

Paper Nutrition interventions for healthy ageing across the lifespan: a conference report

Kalache, Alexandre; Hoogh, Iris M. de; Howlett, Susan E. et al. · 2019 · European Journal of Nutrition · DOI

Full title: Nutrition interventions for healthy ageing across the lifespan: a conference report

Authors: Kalache, Alexandre; Hoogh, Iris M. de; Howlett, Susan E.; Kennedy, Brian K.; Eggersdorfer, Manfred; Marsman, Daniel S.; Shao, Anwen; Griffiths, James C.

Year: 2019

Venue: European Journal of Nutrition

DOI: https://doi.org/10.1007/s00394-019-02027-z

Paper Involvement of oxidative stress in SAMP10 mice with age-related neurodegeneration.

Wang, Jun; Lei, Hongtao; Hou, Jincai et al. · 2015 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · DOI

Full title: Involvement of oxidative stress in SAMP10 mice with age-related neurodegeneration.

Authors: Wang, Jun; Lei, Hongtao; Hou, Jincai; Liu, Jianxun

Year: 2015

Venue: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

DOI: https://doi.org/10.1007/s10072-014-2029-5

Paper Alternative splicing in aging and longevity.

Bhadra, Malini; Howell, Porsha; Dutta, Sneha et al. · 2020 · Human genetics · DOI

Full title: Alternative splicing in aging and longevity.

Authors: Bhadra, Malini; Howell, Porsha; Dutta, Sneha; Heintz, Caroline; Mair, William B

Year: 2020

Venue: Human genetics

DOI: https://doi.org/10.1007/s00439-019-02094-6

Paper Metformin as a geroprotector: experimental and clinical evidence

V. Piskovatska; N. Stefanyshyn; K. Storey et al. · 2018 · Biogerontology (Dordrecht) · DOI

Full title: Metformin as a geroprotector: experimental and clinical evidence

Authors: V. Piskovatska; N. Stefanyshyn; K. Storey; A. Vaiserman; O. Lushchak

Year: 2018

Venue: Biogerontology (Dordrecht)

DOI: https://doi.org/10.1007/s10522-018-9773-5

Paper The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae.

Odoh, Chuks Kenneth; Guo, Xiaojia; Arnone, James T et al. · 2022 · Biogerontology · DOI

Full title: The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae.

Authors: Odoh, Chuks Kenneth; Guo, Xiaojia; Arnone, James T; Wang, Xueying; Zhao, Zongbao K

Year: 2022

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-022-09958-x

Paper Geroprotective effects of GdVO4:Eu3 + nanoparticles, metformin and calorie restriction in male rats with accelerated aging induced by overnutrition in early postnatal ontogenesis

Y. Nikitchenko; V. Klochkov; N. Kavok et al. · 2024 · Biogerontology (Dordrecht) · DOI

Full title: Geroprotective effects of GdVO4:Eu3 + nanoparticles, metformin and calorie restriction in male rats with accelerated aging induced by overnutrition in early postnatal ontogenesis

Authors: Y. Nikitchenko; V. Klochkov; N. Kavok; Nina Karpenko; S. Yefimova; V. P. Semynozhenko; I. V. Nikitchenko; Anatoly I Bozhkov

Year: 2024

Venue: Biogerontology (Dordrecht)

DOI: https://doi.org/10.1007/s10522-024-10156-0

Paper Mitochondria-targeted senotherapeutic interventions.

Atayik, Mehmet Can; Çakatay, Ufuk · 2022 · Biogerontology · DOI

Full title: Mitochondria-targeted senotherapeutic interventions.

Authors: Atayik, Mehmet Can; Çakatay, Ufuk

Year: 2022

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-022-09973-y

Paper “Development of gerontology would be more effective under governmental support”: an interview with Vladimir N. Anisimov

A. Moskalev · 2023 · Biogerontology (Dordrecht) · DOI

Full title: “Development of gerontology would be more effective under governmental support”: an interview with Vladimir N. Anisimov

Authors: A. Moskalev

Year: 2023

Venue: Biogerontology (Dordrecht)

DOI: https://doi.org/10.1007/s10522-023-10025-2

Paper Identification of resibufogenin, a component of toad venom, as a novel senolytic compound in vitro and for potential skin rejuvenation in male mice.

Takaya, Kento; Asou, Toru; Kishi, Kazuo · 2023 · Biogerontology · DOI

Full title: Identification of resibufogenin, a component of toad venom, as a novel senolytic compound in vitro and for potential skin rejuvenation in male mice.

Authors: Takaya, Kento; Asou, Toru; Kishi, Kazuo

Year: 2023

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-023-10043-0

Paper Targeting the epigenetically older individuals for geroprotective trials: the use of DNA methylation clocks.

Sandalova, Elena; Maier, Andrea B · 2024 · Biogerontology · DOI

Full title: Targeting the epigenetically older individuals for geroprotective trials: the use of DNA methylation clocks.

Authors: Sandalova, Elena; Maier, Andrea B

Year: 2024

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-023-10077-4

Paper Application potential of senolytics in clinical treatment.

Li, Tiantian; Li, Shiyuan; Ma, Kefeng et al. · 2024 · Biogerontology · DOI

Full title: Application potential of senolytics in clinical treatment.

Authors: Li, Tiantian; Li, Shiyuan; Ma, Kefeng; Kong, Jinming

Year: 2024

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-023-10084-5

Paper Calorie restriction mimetics against aging and inflammation.

Chaudhary, Sakshi; Chaudhary, Mani Raj; Jena, Manoj Kumar et al. · 2025 · Biogerontology · DOI

Full title: Calorie restriction mimetics against aging and inflammation.

Authors: Chaudhary, Sakshi; Chaudhary, Mani Raj; Jena, Manoj Kumar; Rath, Prasana Kumar; Mishra, Bidyut Prava; Paital, Biswaranjan; Vyas, Ashish; Sahoo, Dipak Kumar; Singh, Prabhakar; Mehdi, Mohammad Murtaza

Year: 2025

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-025-10269-0

Paper Influence of a diet with potential geroprotectors on blood biochemistry and aging-associated markers in domestic cats: a pilot study.

Protopopov, Vladimir A; Sekunov, Alexey V; Toropova, Tatiana V et al. · 2025 · Biogerontology · DOI

Full title: Influence of a diet with potential geroprotectors on blood biochemistry and aging-associated markers in domestic cats: a pilot study.

Authors: Protopopov, Vladimir A; Sekunov, Alexey V; Toropova, Tatiana V; Bryndina, Irina G; Burganova, Dilyara N; Milaev, Vyacheslav B; Sharafislamova, Mariya B; Pozdeev, Sergey V; Moskalev, Alexey A

Year: 2025

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-025-10293-0

Paper Realistic expectations for changes to average human lifespan in the near future.

Johnson, Adiv A · 2025 · Biogerontology · DOI

Full title: Realistic expectations for changes to average human lifespan in the near future.

Authors: Johnson, Adiv A

Year: 2025

Venue: Biogerontology

DOI: https://doi.org/10.1007/s10522-025-10318-8

Paper The Role of DNA Damage and Nutritional Interventions in Aging in Progeroid Mice

Ivar van Galen · DOI

Full title: The Role of DNA Damage and Nutritional Interventions in Aging in Progeroid Mice

Authors: Ivar van Galen

DOI: https://doi.org/10.33540/3179

Paper Senotherapeutic repurposing of metformin for age-related diseases and their signaling pathways.

Turgut, Şeydanur; Atasever, Erdem; Cebe, Tamer et al. · 2025 · Molecular biology reports · DOI

Full title: Senotherapeutic repurposing of metformin for age-related diseases and their signaling pathways.

Authors: Turgut, Şeydanur; Atasever, Erdem; Cebe, Tamer; Andican, Gülnur; Çakatay, Ufuk

Year: 2025

Venue: Molecular biology reports

DOI: https://doi.org/10.1007/s11033-025-10524-0

Paper In case of obesity, longevity-related mechanisms lead to anti-inflammation

Kaya, Mehmet Salih; Bayıroğlu, Fahri; Mıs, Leyla et al. · 2013 · AGE · DOI

Full title: In case of obesity, longevity-related mechanisms lead to anti-inflammation

Authors: Kaya, Mehmet Salih; Bayıroğlu, Fahri; Mıs, Leyla; Kılınç, Dide Kılıçalp; Comba, Bahat

Year: 2013

Venue: AGE

DOI: https://doi.org/10.1007/s11357-013-9598-8

Paper Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.

Csiszar, Anna; Balasubramanian, Priya; Tarantini, Stefano et al. · 2019 · GeroScience · DOI

Full title: Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.

Authors: Csiszar, Anna; Balasubramanian, Priya; Tarantini, Stefano; Yabluchanskiy, Andriy; Zhang, Xin A; Springo, Zsolt; Benbrook, Doris; Sonntag, William E; Ungvari, Zoltan

Year: 2019

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-019-00064-4

Paper A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

Deepa, Sathyaseelan S.; Bhaskaran, Shylesh; Espinoza, Sara et al. · 2017 · GeroScience · DOI

Full title: A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

Authors: Deepa, Sathyaseelan S.; Bhaskaran, Shylesh; Espinoza, Sara; Brooks, Susan V.; McArdle, Anne; Jackson, Malcolm J.; Remmen, Holly Van; Richardson, Arlan

Year: 2017

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-017-9975-9

Paper Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases.

Yang, Jialiang; Peng, Shouneng; Zhang, Bin et al. · 2020 · GeroScience · DOI

Full title: Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases.

Authors: Yang, Jialiang; Peng, Shouneng; Zhang, Bin; Houten, Sander; Schadt, Eric; Zhu, Jun; Suh, Yousin; Tu, Zhidong

Year: 2020

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-019-00106-x

Paper Effect of calorie restriction and refeeding on skin wound healing in the rat

Nicole D. Hunt; Garrick D. Li; Min Zhu et al. · 2012 · AGE · DOI

Full title: Effect of calorie restriction and refeeding on skin wound healing in the rat

Authors: Nicole D. Hunt; Garrick D. Li; Min Zhu; A. Levette; M. Chachich; E. Spangler; Joanne S. Allard; D. Hyun; D. Ingram; R. Cabo

Year: 2012

Venue: AGE

DOI: https://doi.org/10.1007/s11357-011-9321-6

Paper Pterocarpus marsupium extract extends replicative lifespan in budding yeast.

Lee, Mitchell B; Kiflezghi, Michael G; Tsuchiya, Mitsuhiro et al. · 2021 · GeroScience · DOI

Full title: Pterocarpus marsupium extract extends replicative lifespan in budding yeast.

Authors: Lee, Mitchell B; Kiflezghi, Michael G; Tsuchiya, Mitsuhiro; Wasko, Brian; Carr, Daniel T; Uppal, Priya A; Grayden, Katherine A; Elala, Yordanos C; Nguyen, Tu Anh; Wang, Jesse; Ragosti, Priya; Nguyen, Sunny; Zhao, Yan Ting; Kim, Deborah; Thon, Socheata; Sinha, Irika; Tang, Thao T; Tran, Ngoc H B; Tran, Thu H B; Moore, Margarete D; Li, Mary Ann K; Rodriguez, Karl; Promislow, Daniel E L; Kaeberlein, Matt

Year: 2021

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-021-00418-x

Paper Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging

Tarantini, Stefano; Yabluchanskiy, Andriy; Csípő, Tamás et al. · 2019 · GeroScience · DOI

Full title: Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging

Authors: Tarantini, Stefano; Yabluchanskiy, Andriy; Csípő, Tamás; Fülöp, Gábor Áron; Kiss, Tamás; Balasubramanian, Priya; DelFavero, Jordan; Ahire, Chetan; Ungvari, Anna; Nyúl‐Tóth, Ádám; Farkas, Eszter; Benyó, Zoltán; Tóth, Attila; Csiszár, Anna; Ungvári, Zoltán

Year: 2019

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-019-00101-2

Paper Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis

Phillips, Eleanor J.; Simons, Mirre J. P. · 2022 · GeroScience · DOI

Full title: Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis

Authors: Phillips, Eleanor J.; Simons, Mirre J. P.

Year: 2022

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00691-4

Paper Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease.

Sonsalla, Michelle M; Lamming, Dudley W · 2023 · GeroScience · DOI

Full title: Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease.

Authors: Sonsalla, Michelle M; Lamming, Dudley W

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00782-w

Paper Testing the evidence that lifespan-extending compound interventions are conserved across laboratory animal model species.

Bene, Michael; Salmon, Adam B · 2023 · GeroScience · DOI

Full title: Testing the evidence that lifespan-extending compound interventions are conserved across laboratory animal model species.

Authors: Bene, Michael; Salmon, Adam B

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-022-00722-0

Paper Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice

Marcozzi, Serena; Bigossi, Giorgia; Giuliani, Maria Elisa et al. · 2023 · GeroScience · DOI

Full title: Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice

Authors: Marcozzi, Serena; Bigossi, Giorgia; Giuliani, Maria Elisa; Giacconi, Robertina; Cardelli, Maurizio; Piacenza, Francesco; Orlando, Fiorenza; Segala, Agnese; Valerio, Alessandra; Nisoli, Enzo; Brunetti, Dario; Puca, Annibale Alessandro; Boschi, Federico; Gaetano, Carlo; Mongelli, Alessia; Lattanzio, Fabrizia; Provinciali, Mauro; Malavolta, Marco

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00737-1

Paper Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design.

Ruggiero, Alistaire D; Vemuri, Ravichandra; Blawas, Megan et al. · 2023 · GeroScience · DOI

Full title: Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design.

Authors: Ruggiero, Alistaire D; Vemuri, Ravichandra; Blawas, Megan; Long, Masha; DeStephanis, Darla; Williams, Abigail G; Chen, Haiying; Justice, Jamie N; Macauley, Shannon L; Day, Steven M; Kavanagh, Kylie

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00830-5

Paper Blazing a trail for the clinical use of rapamycin as a geroprotecTOR.

Konopka, Adam R; Lamming, Dudley W; RAP PAC Investigators et al. · 2023 · GeroScience · DOI

Full title: Blazing a trail for the clinical use of rapamycin as a geroprotecTOR.

Authors: Konopka, Adam R; Lamming, Dudley W; RAP PAC Investigators; EVERLAST Investigators

Year: 2023

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-00935-x

Paper The regeneration model of aging and its practical implications

Erik Dassoff · 2026 · Discover medicine · DOI

Full title: The regeneration model of aging and its practical implications

Authors: Erik Dassoff

Year: 2026

Venue: Discover medicine

DOI: https://doi.org/10.1007/s44337-025-00558-5

Paper [Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions].

Proshkina, E N; Solovev, I A; Shaposhnikov, M V et al. · 2020 · Molekuliarnaia biologiia · DOI

Full title: [Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions].

Authors: Proshkina, E N; Solovev, I A; Shaposhnikov, M V; Moskalev, A A

Year: 2020

Venue: Molekuliarnaia biologiia

DOI: https://doi.org/10.31857/S0026898420060099

Paper Targeting glucose metabolism for healthy aging.

Brewer, Rachel A; Gibbs, Victoria K; Smith, Daniel L · 2016 · Nutrition and healthy aging · DOI

Full title: Targeting glucose metabolism for healthy aging.

Authors: Brewer, Rachel A; Gibbs, Victoria K; Smith, Daniel L

Year: 2016

Venue: Nutrition and healthy aging

DOI: https://doi.org/10.3233/NHA-160007

Paper Leveraging budding yeast Saccharomyces cerevisiae for discovering aging modulation substances for functional food

Wang, Shaoyu · 2019 · Functional Foods in Health and Disease · DOI

Full title: Leveraging budding yeast Saccharomyces cerevisiae for discovering aging modulation substances for functional food

Authors: Wang, Shaoyu

Year: 2019

Venue: Functional Foods in Health and Disease

DOI: https://doi.org/10.31989/ffhd.v9i5.575

Paper Sexual dimorphism in the response to dietary restriction in mice: A systematic review of the literature

Mitchell, Sarah J.; Mitchell, James R. · 2022 · Nutrition and Healthy Aging · DOI

Full title: Sexual dimorphism in the response to dietary restriction in mice: A systematic review of the literature

Authors: Mitchell, Sarah J.; Mitchell, James R.

Year: 2022

Venue: Nutrition and Healthy Aging

DOI: https://doi.org/10.3233/nha-220162

Paper Why do sexes differ in lifespan extension? Sex-specific pathways of aging and underlying mechanisms for dimorphic responses

M. Garratt · 2019 · Nutrition and Healthy Aging · DOI

Full title: Why do sexes differ in lifespan extension? Sex-specific pathways of aging and underlying mechanisms for dimorphic responses

Authors: M. Garratt

Year: 2019

Venue: Nutrition and Healthy Aging

DOI: https://doi.org/10.3233/nha-190067

Paper Multiple Roles of Mitochondria in Aging Processes

Čedíková, Miroslava; Pitule, Pavel; Kripnerová, Michaela et al. · 2016 · Physiological Research · DOI

Full title: Multiple Roles of Mitochondria in Aging Processes

Authors: Čedíková, Miroslava; Pitule, Pavel; Kripnerová, Michaela; Markova, M. N.; Kuncová, Jitka

Year: 2016

Venue: Physiological Research

DOI: https://doi.org/10.33549/physiolres.933538

Paper Integrating evolutionary theory into a framework for the mechanistic evaluation of candidate anti-aging interventions

Aggour, Yusuf; Salguero-Gómez, Rob · 2026 · DOI

Full title: Integrating evolutionary theory into a framework for the mechanistic evaluation of candidate anti-aging interventions

Authors: Aggour, Yusuf; Salguero-Gómez, Rob

Year: 2026

DOI: https://doi.org/10.32942/x25h23

Paper The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

Titorenko, Vladimir I; Harkness, Troy A A · 2012 · Frontiers in physiology · DOI

Full title: The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

Authors: Titorenko, Vladimir I; Harkness, Troy A A

Year: 2012

Venue: Frontiers in physiology

DOI: https://doi.org/10.3389/fphys.2012.00419

Paper Evidence that C/EBP-β LAP Increases Fat Metabolism and Protects Against Diet-Induced Obesity in Response to mTOR Inhibition

Alessandro Bitto; Nicole Tatom; T. Krivak et al. · 2021 · Frontiers in Aging · DOI

Full title: Evidence that C/EBP-β LAP Increases Fat Metabolism and Protects Against Diet-Induced Obesity in Response to mTOR Inhibition

Authors: Alessandro Bitto; Nicole Tatom; T. Krivak; Peter Grotz; M. Kaeberlein

Year: 2021

Venue: Frontiers in Aging

DOI: https://doi.org/10.3389/fragi.2021.738512

Paper Sirtuin activators as an anti-aging intervention for longevity

Puja Sah; A. K. Rai; D. Syiem · 2025 · Exploration of Drug Science · DOI

Full title: Sirtuin activators as an anti-aging intervention for longevity

Authors: Puja Sah; A. K. Rai; D. Syiem

Year: 2025

Venue: Exploration of Drug Science

DOI: https://doi.org/10.37349/eds.2025.100881

Paper Study of the possibility of using metformin by intranasal administration for the correction of behavioral and cognitive dysfunctions of rats

A. Z. Hafizova; I. I. Semina · 2025 · Pharmacokinetics and Pharmacodynamics · DOI

Full title: Study of the possibility of using metformin by intranasal administration for the correction of behavioral and cognitive dysfunctions of rats

Authors: A. Z. Hafizova; I. I. Semina

Year: 2025

Venue: Pharmacokinetics and Pharmacodynamics

DOI: https://doi.org/10.37489/2587-7836-2025-1-35-42

Paper RUSS-AGE: developed research protocol for the creation of Russian biological age calculators

Melnitskaia, A. A.; Matchekhina, L. V.; Ткачева, О. Н. et al. · 2024 · Russian Journal of Geriatric Medicine · DOI

Full title: RUSS-AGE: developed research protocol for the creation of Russian biological age calculators

Authors: Melnitskaia, A. A.; Matchekhina, L. V.; Ткачева, О. Н.; Ilyushchenko, A. K.; Tyazhelnikov, Andrey A.; Polunin, V.S.; Yumukyan, Alexander V.; Стражеско, И. Д.

Year: 2024

Venue: Russian Journal of Geriatric Medicine

DOI: https://doi.org/10.37586/2686-8636-4-2023-239-247

Paper Sarcopenia and Muscle Aging: A Brief Overview

Dao, Tam; Green, Alex E.; Kim, Yun-A et al. · 2020 · Endocrinology and Metabolism · DOI

Full title: Sarcopenia and Muscle Aging: A Brief Overview

Authors: Dao, Tam; Green, Alex E.; Kim, Yun-A; Bae, Sung‐Jin; Ha, Ki‐Tae; Gariani, Karim; Lee, Mi-ra; Menzies, Keir J.; Ryu, Dongryeol

Year: 2020

Venue: Endocrinology and Metabolism

DOI: https://doi.org/10.3803/enm.2020.405

Paper Biotechnology and Modern Clinical Medicine: A Multidisciplinary Narrative Review Integrating Artificial Intelligence and Aging Research

Victor Junior Godinez Vazquez · 2026 · International Journal of Scientific Research and Modern Technology · DOI

Full title: Biotechnology and Modern Clinical Medicine: A Multidisciplinary Narrative Review Integrating Artificial Intelligence and Aging Research

Authors: Victor Junior Godinez Vazquez

Year: 2026

Venue: International Journal of Scientific Research and Modern Technology

DOI: https://doi.org/10.38124/ijsrmt.v5i1.1145

Paper Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging.

Ninomiya, Kenta; Ortaleza, Krystal; Lopez, Josue A et al. · 2026 · Journal of visualized experiments : JoVE · DOI

Full title: Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging.

Authors: Ninomiya, Kenta; Ortaleza, Krystal; Lopez, Josue A; Terskikh, Alexey V

Year: 2026

Venue: Journal of visualized experiments : JoVE

DOI: https://doi.org/10.3791/69057

Paper Recent Advances in Anti-Aging Medicine.

Son, Da-Hye; Park, Woo-Jin; Lee, Yong-Jae · 2019 · Korean journal of family medicine · DOI

Full title: Recent Advances in Anti-Aging Medicine.

Authors: Son, Da-Hye; Park, Woo-Jin; Lee, Yong-Jae

Year: 2019

Venue: Korean journal of family medicine

DOI: https://doi.org/10.4082/kjfm.19.0087

Paper Longevity interventions temporally scale healthspan in Caenorhabditis elegans.

Statzer, Cyril; Reichert, Peter; Dual, Jürg et al. · 2022 · iScience · DOI

Full title: Longevity interventions temporally scale healthspan in Caenorhabditis elegans.

Authors: Statzer, Cyril; Reichert, Peter; Dual, Jürg; Ewald, Collin Y

Year: 2022

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2022.103983

Paper Damage-induced aging and perpetual motion

M. Blagosklonny · 2013 · Cell Cycle · DOI

Full title: Damage-induced aging and perpetual motion

Authors: M. Blagosklonny

Year: 2013

Venue: Cell Cycle

DOI: https://doi.org/10.4161/cc.26015

Paper Rapalogs in cancer prevention

M. Blagosklonny · 2012 · Cancer Biology & Therapy · DOI

Full title: Rapalogs in cancer prevention

Authors: M. Blagosklonny

Year: 2012

Venue: Cancer Biology & Therapy

DOI: https://doi.org/10.4161/cbt.22859

Paper Selective anti-cancer agents as anti-aging drugs.

Blagosklonny, Mikhail V · 2013 · Cancer biology & therapy · DOI

Full title: Selective anti-cancer agents as anti-aging drugs.

Authors: Blagosklonny, Mikhail V

Year: 2013

Venue: Cancer biology & therapy

DOI: https://doi.org/10.4161/cbt.27350

Paper Origin of Thymic Adipocytes in Aging: Incidental to Thymopoiesis or Instigator of Immunosenescence? (132.22)

V. Dixit; Y. Youm; Hyunwon Yang et al. · 2010 · Journal of Immunology · DOI

Full title: Origin of Thymic Adipocytes in Aging: Incidental to Thymopoiesis or Instigator of Immunosenescence? (132.22)

Authors: V. Dixit; Y. Youm; Hyunwon Yang; C. Venkov; N. Manley; E. Nielson; T. Leff; B. Vandanmagsar

Year: 2010

Venue: Journal of Immunology

DOI: https://doi.org/10.4049/jimmunol.184.supp.132.22

Paper Applying Longevity and Anti-Aging Research to Athletic Performance: Strategies to Extend Playing Careers, Reduce Injury Risk, and Accelerate Recovery

Ansh Riyal; Taruna Agarwal; J. Leddo et al. · 2025 · International journal of social science and economic research · DOI

Full title: Applying Longevity and Anti-Aging Research to Athletic Performance: Strategies to Extend Playing Careers, Reduce Injury Risk, and Accelerate Recovery

Authors: Ansh Riyal; Taruna Agarwal; J. Leddo; Dev Agarwal; Vidush Chandrasekar; Vihaan Penumatsa; Nihitha Yerram; Sara Tun; Riya Biswas; Collin O’Brien; Sarayu Thatiparthi; Zarah Koroth; Xinyu Jiang; Ajay Raju; A. Penmetsa; Ishwarya Ramineni; Shang Lyu; Deetya Hamilpur; Aashi Bandam; Sai Varun Konagalla; Yousef Malik; Anika Dubey; Eva Sonis; Adam Malik; Kriti Regandla

Year: 2025

Venue: International journal of social science and economic research

DOI: https://doi.org/10.46609/ijsser.2025.v10i09.054

Paper Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena.

Martin-Castillo, Begoña; Vazquez-Martin, Alejandro; Oliveras-Ferraros, Cristina et al. · 2010 · Cell cycle (Georgetown, Tex.) · DOI

Full title: Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena.

Authors: Martin-Castillo, Begoña; Vazquez-Martin, Alejandro; Oliveras-Ferraros, Cristina; Menendez, Javier A

Year: 2010

Venue: Cell cycle (Georgetown, Tex.)

DOI: https://doi.org/10.4161/cc.9.6.10994

Paper Discrimination of Normal from Slow-Aging Mice by Plasma Metabolomic and Proteomic Features Datasets

Bretton, Badenoch,; Oliver, Fiehn,; Noa, Rappaport, et al. · 2025 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: Discrimination of Normal from Slow-Aging Mice by Plasma Metabolomic and Proteomic Features Datasets

Authors: Bretton, Badenoch,; Oliver, Fiehn,; Noa, Rappaport,; Kengo, Watanabe,; Pranjal, Srivastava,; Robert, Moritz,; Sriram, Chandrasekaran,; Richard, Miller,

Year: 2025

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.17780310

Paper Discrimination of Normal from Slow-Aging Mice by Plasma Metabolomic and Proteomic Features Datasets

Bretton, Badenoch,; Oliver, Fiehn,; Noa, Rappaport, et al. · 2025 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: Discrimination of Normal from Slow-Aging Mice by Plasma Metabolomic and Proteomic Features Datasets

Authors: Bretton, Badenoch,; Oliver, Fiehn,; Noa, Rappaport,; Kengo, Watanabe,; Pranjal, Srivastava,; Robert, Moritz,; Sriram, Chandrasekaran,; Richard, Miller,

Year: 2025

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.17780310

Paper The Theory of Medical Irreversibility

Bresciano, Claudio · 2026 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: The Theory of Medical Irreversibility

Authors: Bresciano, Claudio

Year: 2026

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.18155211

Paper The Theory of Medical Irreversibility

Bresciano, Claudio · 2026 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: The Theory of Medical Irreversibility

Authors: Bresciano, Claudio

Year: 2026

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.18155211

Paper ANALYSIS OF SCIENTIFIC SOURCES REGARDING THEORIES OF AGING AND LONGEVITY

Knyhynytska, R. · 2022 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: ANALYSIS OF SCIENTIFIC SOURCES REGARDING THEORIES OF AGING AND LONGEVITY

Authors: Knyhynytska, R.

Year: 2022

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.6907683

Paper Two genes of interest from comparative longevity genomics: FAM126B and OBSCN

Bahry, David · 2022 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: Two genes of interest from comparative longevity genomics: FAM126B and OBSCN

Authors: Bahry, David

Year: 2022

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.7080278

Paper El envejecimiento: ¿Podemos frenarlo? Autofagia/Nutrición. Reprogramación Celular Segunda Parte

Garrido, Marı́a del Rosario; Garrido, María del Rosario · 2023 · Revista de la Facultad de Farmacia · DOI

Full title: El envejecimiento: ¿Podemos frenarlo? Autofagia/Nutrición. Reprogramación Celular Segunda Parte

Authors: Garrido, Marı́a del Rosario; Garrido, María del Rosario

Year: 2023

Venue: Revista de la Facultad de Farmacia

DOI: https://doi.org/10.54305/rffucv.2023.86.3.16

Paper Replication Data for: The Biohacking Shadow Market: Constructing Legitimacy and Shaping Institutional Voids in the GCC

Albous, Mohammad Rashed · 2026 · Zenodo (CERN European Organization for Nuclear Research) · DOI

Full title: Replication Data for: The Biohacking Shadow Market: Constructing Legitimacy and Shaping Institutional Voids in the GCC

Authors: Albous, Mohammad Rashed

Year: 2026

Venue: Zenodo (CERN European Organization for Nuclear Research)

DOI: https://doi.org/10.5281/zenodo.18721165

Paper Cellular senescence, aging, and age-related disease: Special issue of BMB Reports in 2019.

Lee, Jae-Seon · 2019 · BMB reports · DOI

Full title: Cellular senescence, aging, and age-related disease: Special issue of BMB Reports in 2019.

Authors: Lee, Jae-Seon

Year: 2019

Venue: BMB reports

DOI: https://doi.org/10.5483/BMBRep.2019.52.1.002

Paper Multi-level remodeling of transcriptional landscapes in aging and longevity.

Lai, Rochelle W; Lu, Ryan; Danthi, Prakroothi S et al. · 2019 · BMB reports · DOI

Full title: Multi-level remodeling of transcriptional landscapes in aging and longevity.

Authors: Lai, Rochelle W; Lu, Ryan; Danthi, Prakroothi S; Bravo, Juan I; Goumba, Alexandre; Sampathkumar, Nirmal Kumar; Benayoun, Bérénice A

Year: 2019

Venue: BMB reports

DOI: https://doi.org/10.5483/BMBRep.2019.52.1.296

Paper Cell Nonautonomous Regulation of Longevity and Behavior

Kitto, Elizabeth S · 2025 · Deep Blue (University of Michigan) · DOI

Full title: Cell Nonautonomous Regulation of Longevity and Behavior

Authors: Kitto, Elizabeth S

Year: 2025

Venue: Deep Blue (University of Michigan)

DOI: https://doi.org/10.7302/26835

Paper Responses to Many Anti-Aging Interventions Are Sexually Dimorphic.

Bartke, Andrzej; Hascup, Erin; Hascup, Kevin · 2024 · The world journal of men's health · DOI

Full title: Responses to Many Anti-Aging Interventions Are Sexually Dimorphic.

Authors: Bartke, Andrzej; Hascup, Erin; Hascup, Kevin

Year: 2024

Venue: The world journal of men's health

DOI: https://doi.org/10.5534/wjmh.230015

Paper Drugs with Senolytic Activity: Prospects and Possible Limitations

G. Morgunova; A. N. Khokhlov · 2023 · Moscow University Biological Sciences Bulletin · DOI

Full title: Drugs with Senolytic Activity: Prospects and Possible Limitations

Authors: G. Morgunova; A. N. Khokhlov

Year: 2023

Venue: Moscow University Biological Sciences Bulletin

DOI: https://doi.org/10.3103/s0096392524600455

Paper Translational longevity medicine: a Swiss perspective in an ageing country

Ruckstuhl, Marco M.; Bischof, Evelyne; Blatch, Dana et al. · 2023 · Swiss Medical Weekly · DOI

Full title: Translational longevity medicine: a Swiss perspective in an ageing country

Authors: Ruckstuhl, Marco M.; Bischof, Evelyne; Blatch, Dana; Buhayer, Aliki; Goldhahn, Jörg; Battegay, Edouard; Tichelli, André; Ewald, Collin Y.

Year: 2023

Venue: Swiss Medical Weekly

DOI: https://doi.org/10.57187/smw.2023.40088

Paper CITP Automated Lifespan Machine (ALM) SOPs

Program, Caenorhabditis Intervention Testing · 2019 · Figshare · DOI

Full title: CITP Automated Lifespan Machine (ALM) SOPs

Authors: Program, Caenorhabditis Intervention Testing

Year: 2019

Venue: Figshare

DOI: https://doi.org/10.6084/m9.figshare.c.4580546.v1

Paper An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans.

Safina, Ksenia R; Kotliar, Dylan A; Curtis, Michelle et al. · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans.

Authors: Safina, Ksenia R; Kotliar, Dylan A; Curtis, Michelle; Good, Jonathan D; Weng, Chen; David, Shawn; Raychaudhuri, Soumya; Kreso, Antonia; Trowbridge, Jennifer; Sankaran, Vijay G; van Galen, Peter

Year: 2025

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2025.09.01.673389

Paper Current Understanding of p53-Dependent Cellular Senescence in Health Disparities: Molecular Insights and Public-Health Strategies

Deborah Pelumi Fadipe; Oluwapelumi Hannah Sonoiki; L. C. Iwuala et al. · 2025 · Journal of Life Science and Public Health · DOI

Full title: Current Understanding of p53-Dependent Cellular Senescence in Health Disparities: Molecular Insights and Public-Health Strategies

Authors: Deborah Pelumi Fadipe; Oluwapelumi Hannah Sonoiki; L. C. Iwuala; Chinemerem David Akujuobi; Confidence Nkechinyerem Chikezie; C. G. Ezeah

Year: 2025

Venue: Journal of Life Science and Public Health

DOI: https://doi.org/10.69739/jlsph.v1i2.813

Paper Glycine and aging: Evidence and mechanisms.

Adiv A. Johnson; Trinna L. Cuellar · 2023 · Ageing Research Reviews · DOI

Full title: Glycine and aging: Evidence and mechanisms.

Authors: Adiv A. Johnson; Trinna L. Cuellar

Year: 2023

Venue: Ageing Research Reviews

DOI: https://doi.org/10.1016/j.arr.2023.101922

Paper Artificial intelligence for aging and longevity research: Recent advances and perspectives.

Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin et al. · 2019 · Ageing research reviews · DOI

Full title: Artificial intelligence for aging and longevity research: Recent advances and perspectives.

Authors: Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin; Scheibye-Knudsen, Morten; Moskalev, Alexey; Aliper, Alex

Year: 2019

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2018.11.003

Paper Therapeutic effect of dietary ingredients on cellular senescence in animals and humans: A systematic review.

Guan, Lihuan; Eisenmenger, Anna; Crasta, Karen C et al. · 2024 · Ageing research reviews · DOI

Full title: Therapeutic effect of dietary ingredients on cellular senescence in animals and humans: A systematic review.

Authors: Guan, Lihuan; Eisenmenger, Anna; Crasta, Karen C; Sandalova, Elena; Maier, Andrea B

Year: 2024

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102238

Paper The immunosenescence clock: A new method for evaluating biological age and predicting mortality risk.

Li, Shuyu; Wang, Ke; Wu, Jingni et al. · 2025 · Ageing research reviews · DOI

Full title: The immunosenescence clock: A new method for evaluating biological age and predicting mortality risk.

Authors: Li, Shuyu; Wang, Ke; Wu, Jingni; Zhu, Yongliang

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102653

Paper Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice.

Fuellen, Georg; Kulaga, Anton; Lobentanzer, Sebastian et al. · 2025 · Ageing research reviews · DOI

Full title: Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice.

Authors: Fuellen, Georg; Kulaga, Anton; Lobentanzer, Sebastian; Unfried, Maximilian; Avelar, Roberto A; Palmer, Daniel; Kennedy, Brian K

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102617

Paper Hallmarks of aging: A user's guide for comparative biologists.

Biga, Peggy R; Duan, Jingyue E; Young, Tristan E et al. · 2025 · Ageing research reviews · DOI

Full title: Hallmarks of aging: A user's guide for comparative biologists.

Authors: Biga, Peggy R; Duan, Jingyue E; Young, Tristan E; Marks, Jamie R; Bronikowski, Anne; Decena, Louis P; Randolph, Eric C; Pavuluri, Ananya G; Li, Guangsheng; Fang, Yifei; Wilkinson, Gerald S; Singh, Gunjan; Nigrin, Nathan T; Larschan, Erica N; Lonski, Andrew J; Riddle, Nicole C; IISAGE Consortium

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102616

Paper Deep aging clocks: AI-powered strategies for biological age estimation.

Srour, Luma; Bejaoui, Yosra; She, James et al. · 2025 · Ageing research reviews · DOI

Full title: Deep aging clocks: AI-powered strategies for biological age estimation.

Authors: Srour, Luma; Bejaoui, Yosra; She, James; Alam, Tanvir; El Hajj, Nady

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2025.102889

Paper Current nutritional and pharmacological anti-aging interventions.

Ros, Manuel; Carrascosa, José María · 2020 · Biochimica et biophysica acta. Molecular basis of disease · DOI

Full title: Current nutritional and pharmacological anti-aging interventions.

Authors: Ros, Manuel; Carrascosa, José María

Year: 2020

Venue: Biochimica et biophysica acta. Molecular basis of disease

DOI: https://doi.org/10.1016/j.bbadis.2019.165612

Paper In-silico evaluation of aging-related interventions using omics data and predictive modeling.

Fuellen, Georg; Palmer, Daniel; Fruijtier, Claudia et al. · 2025 · Ageing research reviews · DOI

Full title: In-silico evaluation of aging-related interventions using omics data and predictive modeling.

Authors: Fuellen, Georg; Palmer, Daniel; Fruijtier, Claudia; Avelar, Roberto A

Year: 2025

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2025.102777

Paper An automated phenotype-based microscopy screen to identify pro-longevity interventions acting through mitochondria in C. elegans.

Maglioni, Silvia; Arsalan, Nayna; Franchi, Luigi et al. · 2015 · Biochimica et biophysica acta · DOI

Full title: An automated phenotype-based microscopy screen to identify pro-longevity interventions acting through mitochondria in C. elegans.

Authors: Maglioni, Silvia; Arsalan, Nayna; Franchi, Luigi; Hurd, Alexander; Opipari, Anthony W; Glick, Gary D; Ventura, Natascia

Year: 2015

Venue: Biochimica et biophysica acta

DOI: https://doi.org/10.1016/j.bbabio.2015.05.004

Paper The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience - Through the lens of the "900-day rule".

Pabis, Kamil; Barardo, Diogo; Gruber, Jan et al. · 2024 · Ageing research reviews · DOI

Full title: The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience - Through the lens of the "900-day rule".

Authors: Pabis, Kamil; Barardo, Diogo; Gruber, Jan; Sirbu, Olga; Malavolta, Marco; Selvarajoo, Kumar; Kaeberlein, Matt; Kennedy, Brian K

Year: 2024

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102512

Paper Characterization of craniofacial tissue aging in genetically diverse HET3 male mice with longevity treatment of 17-alpha estradiol.

Alsabbagh, Rami; LaVerde, Leah; Chufar, Emma et al. · 2025 · Archives of oral biology · DOI

Full title: Characterization of craniofacial tissue aging in genetically diverse HET3 male mice with longevity treatment of 17-alpha estradiol.

Authors: Alsabbagh, Rami; LaVerde, Leah; Chufar, Emma; Willows, Jake W; Townsend, Kristy L; Peters, Sarah B

Year: 2025

Venue: Archives of oral biology

DOI: https://doi.org/10.1016/j.archoralbio.2024.106170

Paper In vivo effect of an antilipolytic drug (3,5'-dimethylpyrazole) on autophagic proteolysis and autophagy-related gene expression in rat liver.

Donati, Alessio; Ventruti, Annamaria; Cavallini, Gabriella et al. · 2008 · Biochemical and biophysical research communications · DOI

Full title: In vivo effect of an antilipolytic drug (3,5'-dimethylpyrazole) on autophagic proteolysis and autophagy-related gene expression in rat liver.

Authors: Donati, Alessio; Ventruti, Annamaria; Cavallini, Gabriella; Masini, Matilde; Vittorini, Simona; Chantret, Isabelle; Codogno, Patrice; Bergamini, Ettore

Year: 2008

Venue: Biochemical and biophysical research communications

DOI: https://doi.org/10.1016/j.bbrc.2007.12.023

Paper Aging as a catabolic malfunction.

Terman, Alexei; Brunk, Ulf T · 2004 · The international journal of biochemistry & cell biology · DOI

Full title: Aging as a catabolic malfunction.

Authors: Terman, Alexei; Brunk, Ulf T

Year: 2004

Venue: The international journal of biochemistry & cell biology

DOI: https://doi.org/10.1016/j.biocel.2004.03.009

Paper Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling.

Xu, Weitong; Zhao, Tingting; Chen, Honghan et al. · 2022 · Biochemical pharmacology · DOI

Full title: Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling.

Authors: Xu, Weitong; Zhao, Tingting; Chen, Honghan; Huang, Ning; Gong, Hui; Zhang, Jian; Yang, Yu; Li, Tiepeng; Zhang, Gongchang; Gong, Chuhui; Yang, Ming; Xiao, Hengyi

Year: 2022

Venue: Biochemical pharmacology

DOI: https://doi.org/10.1016/j.bcp.2022.115045

Paper Pursuing healthy aging and longevity through natural product and stem cell-driven rejuvenation.

Wu, Di; Xu, Qinzheng; Wu, Shuang et al. · 2025 · Biochemical pharmacology · DOI

Full title: Pursuing healthy aging and longevity through natural product and stem cell-driven rejuvenation.

Authors: Wu, Di; Xu, Qinzheng; Wu, Shuang; Tan, Jiachen; Khan, Faheem Ahmed; Pandupuspitasari, Nuruliarizki Shinta; Huang, Chunjie

Year: 2025

Venue: Biochemical pharmacology

DOI: https://doi.org/10.1016/j.bcp.2025.117359

Paper PGC-1alpha in aging and anti-aging interventions.

Anderson, Rozalyn; Prolla, Tomas · 2009 · Biochimica et biophysica acta · DOI

Full title: PGC-1alpha in aging and anti-aging interventions.

Authors: Anderson, Rozalyn; Prolla, Tomas

Year: 2009

Venue: Biochimica et biophysica acta

DOI: https://doi.org/10.1016/j.bbagen.2009.04.005

Paper Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.

Liao, Keng-Mao; Chen, Chih-Jung; Luo, Wei-Jia et al. · 2023 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.

Authors: Liao, Keng-Mao; Chen, Chih-Jung; Luo, Wei-Jia; Hsu, Chen-Wei; Yu, Sung-Liang; Yang, Pan-Chyr; Su, Kang-Yi

Year: 2023

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2023.114616

Paper Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle.

Hamrick, Mark W; Fulzele, Sadanand; Isales, Carlos M et al. · 2025 · Biochimie · DOI

Full title: Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle.

Authors: Hamrick, Mark W; Fulzele, Sadanand; Isales, Carlos M; McGee-Lawrence, Meghan

Year: 2025

Venue: Biochimie

DOI: https://doi.org/10.1016/j.biochi.2025.11.010

Paper Frentizole derivatives with mTOR inhibiting and senomorphic properties.

Chrienova, Zofia; Rysanek, David; Novak, Josef et al. · 2023 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Frentizole derivatives with mTOR inhibiting and senomorphic properties.

Authors: Chrienova, Zofia; Rysanek, David; Novak, Josef; Vasicova, Pavla; Oleksak, Patrik; Andrys, Rudolf; Skarka, Adam; Dumanovic, Jelena; Milovanovic, Zoran; Jacevic, Vesna; Chvojkova, Marketa; Holubova, Kristina; Vales, Karel; Skoupilova, Veronika; Valko, Marian; Jomova, Klaudia; Alomar, Suliman Y; Botelho, Fernanda D; Franca, Tanos C C; Kuca, Kamil; Hodny, Zdenek; Nepovimova, Eugenie

Year: 2023

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2023.115600

Paper Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight.

Pozzo, Lisa Dal; Xu, Zhe; Lin, Shan et al. · 2024 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight.

Authors: Pozzo, Lisa Dal; Xu, Zhe; Lin, Shan; Wang, Jida; Wang, Ying; Enechojo, Ogbe Susan; Abankwah, Joseph Kofi; Peng, Yanfei; Chu, Xiaoqian; Zhou, Huifang; Bian, Yuhong

Year: 2024

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2024.116592

Paper Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies.

Wang, Yao; Wang, Ying; Yang, Ming et al. · 2021 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · DOI

Full title: Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies.

Authors: Wang, Yao; Wang, Ying; Yang, Ming; Ma, Xingjie

Year: 2021

Venue: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI: https://doi.org/10.1016/j.biopha.2020.111191

Paper Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions.

Petkovich, Daniel A; Podolskiy, Dmitriy I; Lobanov, Alexei V et al. · 2017 · Cell metabolism · DOI

Full title: Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions.

Authors: Petkovich, Daniel A; Podolskiy, Dmitriy I; Lobanov, Alexei V; Lee, Sang-Goo; Miller, Richard A; Gladyshev, Vadim N

Year: 2017

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2017.03.016

Paper Rejuvenation of the Aging Heart: Molecular Determinants and Applications.

Alibhai, Faisal J; Li, Ren-Ke · 2024 · The Canadian journal of cardiology · DOI

Full title: Rejuvenation of the Aging Heart: Molecular Determinants and Applications.

Authors: Alibhai, Faisal J; Li, Ren-Ke

Year: 2024

Venue: The Canadian journal of cardiology

DOI: https://doi.org/10.1016/j.cjca.2024.03.004

Paper Enhanced cellular longevity arising from environmental fluctuations.

Liu, Yuting; Zhou, Zhen; Wu, Songlin et al. · 2023 · bioRxiv : the preprint server for biology · DOI

Full title: Enhanced cellular longevity arising from environmental fluctuations.

Authors: Liu, Yuting; Zhou, Zhen; Wu, Songlin; Ni, Gavin; Zhang, Alex; Tsimring, Lev S; Hasty, Jeff; Hao, Nan

Year: 2023

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2023.07.05.547867

Paper Rapamycin Extends Life Span in Apc Colon Cancer FAP Model

Parihar, Manish; Dodds, Sherry G.; Hubbard, Gene B. et al. · 2020 · Clinical Colorectal Cancer · DOI

Full title: Rapamycin Extends Life Span in Apc Colon Cancer FAP Model

Authors: Parihar, Manish; Dodds, Sherry G.; Hubbard, Gene B.; Javors, Martin A.; Strong, Randy; Hasty, Paul; Sharp, Z. Dave

Year: 2020

Venue: Clinical Colorectal Cancer

DOI: https://doi.org/10.1016/j.clcc.2020.08.006

Paper Distinct longevity mechanisms across and within species and their association with aging.

Tyshkovskiy, Alexander; Ma, Siming; Shindyapina, Anastasia V et al. · 2023 · Cell · DOI

Full title: Distinct longevity mechanisms across and within species and their association with aging.

Authors: Tyshkovskiy, Alexander; Ma, Siming; Shindyapina, Anastasia V; Tikhonov, Stanislav; Lee, Sang-Goo; Bozaykut, Perinur; Castro, José P; Seluanov, Andrei; Schork, Nicholas J; Gorbunova, Vera; Dmitriev, Sergey E; Miller, Richard A; Gladyshev, Vadim N

Year: 2023

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2023.05.002

Paper Biomarkers of aging for the identification and evaluation of longevity interventions.

Moqri, Mahdi; Herzog, Chiara; Poganik, Jesse R et al. · 2023 · Cell · DOI

Full title: Biomarkers of aging for the identification and evaluation of longevity interventions.

Authors: Moqri, Mahdi; Herzog, Chiara; Poganik, Jesse R; Biomarkers of Aging Consortium; Justice, Jamie; Belsky, Daniel W; Higgins-Chen, Albert; Moskalev, Alexey; Fuellen, Georg; Cohen, Alan A; Bautmans, Ivan; Widschwendter, Martin; Ding, Jingzhong; Fleming, Alexander; Mannick, Joan; Han, Jing-Dong Jackie; Zhavoronkov, Alex; Barzilai, Nir; Kaeberlein, Matt; Cummings, Steven; Kennedy, Brian K; Ferrucci, Luigi; Horvath, Steve; Verdin, Eric; Maier, Andrea B; Snyder, Michael P; Sebastiano, Vittorio; Gladyshev, Vadim N

Year: 2023

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2023.08.003

Paper SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.

Tian, Xiao; Firsanov, Denis; Zhang, Zhihui et al. · 2019 · Cell · DOI

Full title: SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.

Authors: Tian, Xiao; Firsanov, Denis; Zhang, Zhihui; Cheng, Yang; Luo, Lingfeng; Tombline, Gregory; Tan, Ruiyue; Simon, Matthew; Henderson, Steven; Steffan, Janine; Goldfarb, Audrey; Tam, Jonathan; Zheng, Kitty; Cornwell, Adam; Johnson, Adam; Yang, Jiang-Nan; Mao, Zhiyong; Manta, Bruno; Dang, Weiwei; Zhang, Zhengdong; Vijg, Jan; Wolfe, Aaron; Moody, Kelsey; Kennedy, Brian K; Bohmann, Dirk; Gladyshev, Vadim N; Seluanov, Andrei; Gorbunova, Vera

Year: 2019

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2019.03.043

Paper The anti-aging drug Senolytics alleviates vascular endothelial cell senescence by antagonizing the JPX-BRD4-p65 complex.

Mao, Kaili; Zhu, Wensi; Sun, Huayu et al. · 2026 · Cellular signalling · DOI

Full title: The anti-aging drug Senolytics alleviates vascular endothelial cell senescence by antagonizing the JPX-BRD4-p65 complex.

Authors: Mao, Kaili; Zhu, Wensi; Sun, Huayu; Zheng, Hongliang; Fu, Zhenling

Year: 2026

Venue: Cellular signalling

DOI: https://doi.org/10.1016/j.cellsig.2025.112342

Paper Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging.

Janssens, Georges E; Lin, Xin-Xuan; Millan-Ariño, Lluís et al. · 2019 · Cell reports · DOI

Full title: Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging.

Authors: Janssens, Georges E; Lin, Xin-Xuan; Millan-Ariño, Lluís; Kavšek, Alan; Sen, Ilke; Seinstra, Renée I; Stroustrup, Nicholas; Nollen, Ellen A A; Riedel, Christian G

Year: 2019

Venue: Cell reports

DOI: https://doi.org/10.1016/j.celrep.2019.03.044

Paper The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity.

Slack, Cathy; Alic, Nazif; Foley, Andrea et al. · 2015 · Cell · DOI

Full title: The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity.

Authors: Slack, Cathy; Alic, Nazif; Foley, Andrea; Cabecinha, Melissa; Hoddinott, Matthew P; Partridge, Linda

Year: 2015

Venue: Cell

DOI: https://doi.org/10.1016/j.cell.2015.06.023

Paper Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.

Mills, Kathryn F; Yoshida, Shohei; Stein, Liana R et al. · 2016 · Cell metabolism · DOI

Full title: Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.

Authors: Mills, Kathryn F; Yoshida, Shohei; Stein, Liana R; Grozio, Alessia; Kubota, Shunsuke; Sasaki, Yo; Redpath, Philip; Migaud, Marie E; Apte, Rajendra S; Uchida, Koji; Yoshino, Jun; Imai, Shin-Ichiro

Year: 2016

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2016.09.013

Paper Design and optimization of piperlongumine analogs as potent senolytics.

Zhang, Xuan; He, Yonghan; Liu, Xingui et al. · 2024 · Bioorganic & medicinal chemistry letters · DOI

Full title: Design and optimization of piperlongumine analogs as potent senolytics.

Authors: Zhang, Xuan; He, Yonghan; Liu, Xingui; Zhang, Xin; Shi, Peizhong; Wang, Yingying; Zhou, Daohong; Zheng, Guangrong

Year: 2024

Venue: Bioorganic & medicinal chemistry letters

DOI: https://doi.org/10.1016/j.bmcl.2023.129593

Paper Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.

Tyshkovskiy, Alexander; Bozaykut, Perinur; Borodinova, Anastasia A et al. · 2019 · Cell metabolism · DOI

Full title: Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.

Authors: Tyshkovskiy, Alexander; Bozaykut, Perinur; Borodinova, Anastasia A; Gerashchenko, Maxim V; Ables, Gene P; Garratt, Michael; Khaitovich, Philipp; Clish, Clary B; Miller, Richard A; Gladyshev, Vadim N

Year: 2019

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2019.06.018

Paper Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome.

Wang, Tina; Ma, Jianzhu; Hogan, Andrew N et al. · 2020 · Cell systems · DOI

Full title: Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome.

Authors: Wang, Tina; Ma, Jianzhu; Hogan, Andrew N; Fong, Samson; Licon, Katherine; Tsui, Brian; Kreisberg, Jason F; Adams, Peter D; Carvunis, Anne-Ruxandra; Bannasch, Danika L; Ostrander, Elaine A; Ideker, Trey

Year: 2020

Venue: Cell systems

DOI: https://doi.org/10.1016/j.cels.2020.06.006

Paper Apelin/APJ system: A novel promising target for anti-aging intervention.

Qionglin Zhou; Linxi Chen; Mingzhu Tang et al. · 2018 · Clinica chimica acta; international journal of clinical chemistry · DOI

Full title: Apelin/APJ system: A novel promising target for anti-aging intervention.

Authors: Qionglin Zhou; Linxi Chen; Mingzhu Tang; Yu Guo; Lanfang Li

Year: 2018

Venue: Clinica chimica acta; international journal of clinical chemistry

DOI: https://doi.org/10.1016/j.cca.2018.10.011

Paper Mitochondrial regulator PGC-1a-Modulating the modulator.

Miller, Karl N; Clark, Josef P; Anderson, Rozalyn M · 2019 · Current opinion in endocrine and metabolic research · DOI

Full title: Mitochondrial regulator PGC-1a-Modulating the modulator.

Authors: Miller, Karl N; Clark, Josef P; Anderson, Rozalyn M

Year: 2019

Venue: Current opinion in endocrine and metabolic research

DOI: https://doi.org/10.1016/j.coemr.2019.02.002

Paper A nutrigeroscience approach: Dietary macronutrients and cellular senescence.

Calubag, Mariah F; Robbins, Paul D; Lamming, Dudley W · 2024 · Cell metabolism · DOI

Full title: A nutrigeroscience approach: Dietary macronutrients and cellular senescence.

Authors: Calubag, Mariah F; Robbins, Paul D; Lamming, Dudley W

Year: 2024

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2024.07.025

Paper Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation.

Lu, J Yuyang; Simon, Matthew; Zhao, Yang et al. · 2022 · Cell metabolism · DOI

Full title: Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation.

Authors: Lu, J Yuyang; Simon, Matthew; Zhao, Yang; Ablaeva, Julia; Corson, Nancy; Choi, Yongwook; Yamada, KayLene Y H; Schork, Nicholas J; Hood, Wendy R; Hill, Geoffrey E; Miller, Richard A; Seluanov, Andrei; Gorbunova, Vera

Year: 2022

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2022.04.011

Paper Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule.

Kelly, George; Kataura, Tetsushi; Panek, Johan et al. · 2024 · Developmental cell · DOI

Full title: Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule.

Authors: Kelly, George; Kataura, Tetsushi; Panek, Johan; Ma, Gailing; Salmonowicz, Hanna; Davis, Ashley; Kendall, Hannah; Brookes, Charlotte; Ayine-Tora, Daniel Moscoh; Banks, Peter; Nelson, Glyn; Dobby, Laura; Pitrez, Patricia R; Booth, Laura; Costello, Lydia; Richardson, Gavin D; Lovat, Penny; Przyborski, Stefan; Ferreira, Lino; Greaves, Laura; Szczepanowska, Karolina; von Zglinicki, Thomas; Miwa, Satomi; Brown, Max; Flagler, Michael; Oblong, John E; Bascom, Charles C; Carroll, Bernadette; Reynisson, Jóhannes; Korolchuk, Viktor I

Year: 2024

Venue: Developmental cell

DOI: https://doi.org/10.1016/j.devcel.2024.04.020

Paper Hallmarks of aging and immunosenescence: Connecting the dots.

Rodrigues, Leane Perim; Teixeira, Vitória Rodrigues; Alencar-Silva, Thuany et al. · 2021 · Cytokine & growth factor reviews · DOI

Full title: Hallmarks of aging and immunosenescence: Connecting the dots.

Authors: Rodrigues, Leane Perim; Teixeira, Vitória Rodrigues; Alencar-Silva, Thuany; Simonassi-Paiva, Bianca; Pereira, Rinaldo Wellerson; Pogue, Robert; Carvalho, Juliana Lott

Year: 2021

Venue: Cytokine & growth factor reviews

DOI: https://doi.org/10.1016/j.cytogfr.2021.01.006

Paper Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice.

Mitsukuni Yoshida; A. Satoh; Jonathan B. Lin et al. · 2019 · Cell Metabolism · DOI

Full title: Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice.

Authors: Mitsukuni Yoshida; A. Satoh; Jonathan B. Lin; K. Mills; Y. Sasaki; N. Rensing; M. Wong; R. Apte; S. Imai

Year: 2019

Venue: Cell Metabolism

DOI: https://doi.org/10.1016/j.cmet.2019.05.015

Paper Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells.

Bi, Youkun; Qiao, Xinlong; Cai, Zhaokui et al. · 2025 · Cell metabolism · DOI

Full title: Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells.

Authors: Bi, Youkun; Qiao, Xinlong; Cai, Zhaokui; Zhao, Hailian; Ye, Rong; Liu, Qun; Gao, Lin; Liu, Yingqi; Liang, Bo; Liu, Yixuan; Zhang, Yaning; Yang, Zhiguang; Wu, Yanyun; Wang, Huiwen; Jia, Wei; Zeng, Changqing; Jia, Ce; Wu, Hongjin; Xue, Yuanchao; Ji, Guangju

Year: 2025

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2024.11.013

Paper Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems.

Goeminne, Ludger J E; Vladimirova, Anastasiya; Eames, Alec et al. · 2025 · Cell metabolism · DOI

Full title: Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems.

Authors: Goeminne, Ludger J E; Vladimirova, Anastasiya; Eames, Alec; Tyshkovskiy, Alexander; Argentieri, M Austin; Ying, Kejun; Moqri, Mahdi; Gladyshev, Vadim N

Year: 2025

Venue: Cell metabolism

DOI: https://doi.org/10.1016/j.cmet.2024.10.005

Paper Cellular Senescence: A Translational Perspective

Kirkland, James L.; Tchkonia, Tamar · 2017 · EBioMedicine · DOI

Full title: Cellular Senescence: A Translational Perspective

Authors: Kirkland, James L.; Tchkonia, Tamar

Year: 2017

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2017.04.013

Paper Identification of miR-106b-5p as a senolytic miRNA.

Zhang, Tianpeng; Nunes, Allancer; O'Kelly, Ryan et al. · 2025 · EBioMedicine · DOI

Full title: Identification of miR-106b-5p as a senolytic miRNA.

Authors: Zhang, Tianpeng; Nunes, Allancer; O'Kelly, Ryan; Angelini, Luise; Masternak, Michal M; Suh, Yousin; Dong, Xiao; Niedernhofer, Laura J; Robbins, Paul D

Year: 2025

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2025.105810

Paper Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna

A. Shindyapina; Yongmin Cho; Alaattin Kaya et al. · 2022 · Science Advances · DOI

Full title: Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna

Authors: A. Shindyapina; Yongmin Cho; Alaattin Kaya; A. Tyshkovskiy; J. Castro; A. Deik; Juozas Gordevičius; J. Poganik; C. Clish; S. Horvath; L. Peshkin; V. Gladyshev

Year: 2022

Venue: Science Advances

DOI: https://doi.org/10.1126/sciadv.abo5482

Paper Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies.

Lucas, Vasco; Cavadas, Cláudia; Aveleira, Célia Alexandra · 2023 · Pharmacological reviews · DOI

Full title: Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies.

Authors: Lucas, Vasco; Cavadas, Cláudia; Aveleira, Célia Alexandra

Year: 2023

Venue: Pharmacological reviews

DOI: https://doi.org/10.1124/pharmrev.122.000622

Paper Concept of Human Aging Biomarkers.

Kobelyatskaya, Anastasia A; Moskalev, Aleksey A · 2025 · Biochemistry. Biokhimiia · DOI

Full title: Concept of Human Aging Biomarkers.

Authors: Kobelyatskaya, Anastasia A; Moskalev, Aleksey A

Year: 2025

Venue: Biochemistry. Biokhimiia

DOI: https://doi.org/10.1134/S0006297925601704

Paper An Incipient Revolution in the Testing of Anti-aging Strategies.

Mitteldorf, J · 2018 · Biochemistry. Biokhimiia · DOI

Full title: An Incipient Revolution in the Testing of Anti-aging Strategies.

Authors: Mitteldorf, J

Year: 2018

Venue: Biochemistry. Biokhimiia

DOI: https://doi.org/10.1134/S000629791812009X

Paper Potential Geroprotectors - From Bench to Clinic.

Moskalev, Alexey A · 2023 · Biochemistry. Biokhimiia · DOI

Full title: Potential Geroprotectors - From Bench to Clinic.

Authors: Moskalev, Alexey A

Year: 2023

Venue: Biochemistry. Biokhimiia

DOI: https://doi.org/10.1134/S0006297923110056

Paper Models and methods for evaluating geroprotective activity of pharmacological drugs

V. Anisimov; M. Zabezhinski; I. Popovich · 2011 · DOI

Full title: Models and methods for evaluating geroprotective activity of pharmacological drugs

Authors: V. Anisimov; M. Zabezhinski; I. Popovich

Year: 2011

DOI: https://doi.org/10.1134/s2079057011010036

Paper [Metformin reduces the signs of sarcopenia in old OXYS rats].

Kolosova, N G; Vitovtov, A O; Stefanova, N A · 2015 · Advances in gerontology = Uspekhi gerontologii · DOI

Full title: [Metformin reduces the signs of sarcopenia in old OXYS rats].

Authors: Kolosova, N G; Vitovtov, A O; Stefanova, N A

Year: 2015

Venue: Advances in gerontology = Uspekhi gerontologii

DOI: https://doi.org/10.1134/s2079057016010069

Paper SAT0053 Identification of novel drugs with senolytic activity as osteoarthritis therapeutics

U. Nogueira-Recalde; F. Blanco; M. Loza et al. · 2018 · Saturday, 16 JUNE 2018 · DOI

Full title: SAT0053 Identification of novel drugs with senolytic activity as osteoarthritis therapeutics

Authors: U. Nogueira-Recalde; F. Blanco; M. Loza; D. Grassi; P. Robbins; E. Domínguez; B. Caramés

Year: 2018

Venue: Saturday, 16 JUNE 2018

DOI: https://doi.org/10.1136/annrheumdis-2018-eular.3680

Paper GDF11 protein as a geroprotector

V. Khavinson; B. Kuznik; S. Tarnovskaya et al. · 2016 · Biology Bulletin Reviews · DOI

Full title: GDF11 protein as a geroprotector

Authors: V. Khavinson; B. Kuznik; S. Tarnovskaya; N. Linkova

Year: 2016

Venue: Biology Bulletin Reviews

DOI: https://doi.org/10.1134/s207908641602002x

Paper Why and How We Age, and Is That Process Modifiable?

Arking, Robert · 2008 · Progress of Theoretical Physics Supplement · DOI

Full title: Why and How We Age, and Is That Process Modifiable?

Authors: Arking, Robert

Year: 2008

Venue: Progress of Theoretical Physics Supplement

DOI: https://doi.org/10.1143/ptps.173.310

Paper Fisetin, a potential caloric restriction mimetic, attenuates senescence biomarkers in rat erythrocytes.

Sandeep Singh; Geetika Garg; A. Singh et al. · 2019 · Biochemistry and cell biology = Biochimie et biologie cellulaire · DOI

Full title: Fisetin, a potential caloric restriction mimetic, attenuates senescence biomarkers in rat erythrocytes.

Authors: Sandeep Singh; Geetika Garg; A. Singh; A. Bissoyi; S. Rizvi

Year: 2019

Venue: Biochemistry and cell biology = Biochimie et biologie cellulaire

DOI: https://doi.org/10.1139/bcb-2018-0159

Paper Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space.

A. Payne; S. Dodd; C. Leeuwenburgh · 2003 · Journal of applied physiology · DOI

Full title: Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space.

Authors: A. Payne; S. Dodd; C. Leeuwenburgh

Year: 2003

Venue: Journal of applied physiology

DOI: https://doi.org/10.1152/japplphysiol.00758.2003

Paper Calorie Restriction as a Potent Anti-Aging Intervention: Modulation of Oxidative Stress

B. Yu · 2005 · WORLD SCIENTIFIC eBooks · DOI

Full title: Calorie Restriction as a Potent Anti-Aging Intervention: Modulation of Oxidative Stress

Authors: B. Yu

Year: 2005

Venue: WORLD SCIENTIFIC eBooks

DOI: https://doi.org/10.1142/9789812701329_0010

Paper Aging interventions and therapies

S. Rattan · 2005 · WORLD SCIENTIFIC eBooks · DOI

Full title: Aging interventions and therapies

Authors: S. Rattan

Year: 2005

Venue: WORLD SCIENTIFIC eBooks

DOI: https://doi.org/10.1142/5690

Paper The Genomics of Aging at the Single-Cell Scale.

Zhou, Wei; Cao, Junyue · 2025 · Annual review of genomics and human genetics · DOI

Full title: The Genomics of Aging at the Single-Cell Scale.

Authors: Zhou, Wei; Cao, Junyue

Year: 2025

Venue: Annual review of genomics and human genetics

DOI: https://doi.org/10.1146/annurev-genom-120523-024422

Paper In for the long run: Focus on “Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart”

Welle, Stephen; Glueck, Susan B. · 2003 · Physiological Genomics · DOI

Full title: In for the long run: Focus on “Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart”

Authors: Welle, Stephen; Glueck, Susan B.

Year: 2003

Venue: Physiological Genomics

DOI: https://doi.org/10.1152/physiolgenomics.00177.2002

Paper The Impact of Environmental Factors in Influencing Epigenetics Related to Oxidative States in the Cardiovascular System

Angelini, Francesco; Pagano, Francesca; Bordin, Antonella et al. · 2017 · Oxidative Medicine and Cellular Longevity · DOI

Full title: The Impact of Environmental Factors in Influencing Epigenetics Related to Oxidative States in the Cardiovascular System

Authors: Angelini, Francesco; Pagano, Francesca; Bordin, Antonella; Milan, Marika; Chimenti, Isotta; Peruzzi, Mariangela; Valenti, Valentina; Marullo, Antonino; Schirone, Leonardo; Palmerio, Silvia; Sciarretta, Sebastiano; Murdoch, Colin E.; Frati, Giacomo; Falco, Elena De

Year: 2017

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2017/2712751

Paper Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging

Marchi, Saverio; Giorgi, Carlotta; Suski, Jan M. et al. · 2011 · Journal of Signal Transduction · DOI

Full title: Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging

Authors: Marchi, Saverio; Giorgi, Carlotta; Suski, Jan M.; Agnoletto, Chiara; Bononi, Angela; Bonora, Massimo; Marchi, Elena De; Missiroli, Sonia; Patergnani, Simone; Poletti, Federica; Rimessi, Alessandro; Duszyński, Jerzy; Wiȩckowski, Mariusz R.; Pinton, Paolo

Year: 2011

Venue: Journal of Signal Transduction

DOI: https://doi.org/10.1155/2012/329635

Paper Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models

Bruns, Danielle R.; Drake, Joshua C.; Biela, Laurie M. et al. · 2015 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models

Authors: Bruns, Danielle R.; Drake, Joshua C.; Biela, Laurie M.; Peelor, Frederick F.; Miller, Benjamin F.; Hamilton, Karyn L.

Year: 2015

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2015/732596

Paper Gengnianchun Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF‐1 Signalling Pathway

Meng, Fanhui; Li, Jun; Rao, Yanqiu et al. · 2018 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Gengnianchun Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF‐1 Signalling Pathway

Authors: Meng, Fanhui; Li, Jun; Rao, Yanqiu; Wang, Wenjun; Fu, Yan

Year: 2018

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2018/4740739

Paper [Improvement of physical fitness as anti-aging intervention].

Castillo Garzón, Manuel J; Ortega Porcel, Francisco B; Ruiz Ruiz, Jonatan · 2005 · Medicina clinica · DOI

Full title: [Improvement of physical fitness as anti-aging intervention].

Authors: Castillo Garzón, Manuel J; Ortega Porcel, Francisco B; Ruiz Ruiz, Jonatan

Year: 2005

Venue: Medicina clinica

DOI: https://doi.org/10.1157/13071011

Paper Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage

Dingfu Du; Xianan Tang; Yufeng Li et al. · 2022 · Oxidative Medicine and Cellular Longevity · DOI

Full title: Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage

Authors: Dingfu Du; Xianan Tang; Yufeng Li; Yueyue Gao; Runhua Chen; Qian Chen; Jingyi Wen; Tong Wu; Yan Zhang; Huan Lu; Jinjin Zhang; Shixuan Wang

Year: 2022

Venue: Oxidative Medicine and Cellular Longevity

DOI: https://doi.org/10.1155/2022/9144644

Paper Innovating Aging: Promises and Pitfalls on the Road to Life Extension

Vijg, Jan; Grey, Aubrey D.N.J. de · 2014 · Gerontology · DOI

Full title: Innovating Aging: Promises and Pitfalls on the Road to Life Extension

Authors: Vijg, Jan; Grey, Aubrey D.N.J. de

Year: 2014

Venue: Gerontology

DOI: https://doi.org/10.1159/000357670

Paper Abstract 991: Unraveling the role of nicotinamide adenine dinucleotide precursors in pancreatic cancer biology

Faith Nakazzi; Mehrad Zarei; Hallie Graor et al. · 2024 · Cancer Research · DOI

Full title: Abstract 991: Unraveling the role of nicotinamide adenine dinucleotide precursors in pancreatic cancer biology

Authors: Faith Nakazzi; Mehrad Zarei; Hallie Graor; A. Loftus; Omid Hajihassanni; Jordan M Winter

Year: 2024

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2024-991

Paper Frailty Assessment in Animal Models

Heinze-Milne, Stefan; Banga, Shubham; Howlett, Susan E. · 2019 · Gerontology · DOI

Full title: Frailty Assessment in Animal Models

Authors: Heinze-Milne, Stefan; Banga, Shubham; Howlett, Susan E.

Year: 2019

Venue: Gerontology

DOI: https://doi.org/10.1159/000501333

Paper Abstract 603: Repurposing the plant-derived compound apigenin in anticancer and antiaging pipelines

Yu Sun; Hongwei Zhang; Qixia Xu et al. · 2025 · Cancer Research · DOI

Full title: Abstract 603: Repurposing the plant-derived compound apigenin in anticancer and antiaging pipelines

Authors: Yu Sun; Hongwei Zhang; Qixia Xu; Rong Sun; James L. Kirkland

Year: 2025

Venue: Cancer Research

DOI: https://doi.org/10.1158/1538-7445.am2025-603

Paper Chronobiology of Aging: A Mini-Review.

Cornelissen, Germaine; Otsuka, Kuniaki · 2017 · Gerontology · DOI

Full title: Chronobiology of Aging: A Mini-Review.

Authors: Cornelissen, Germaine; Otsuka, Kuniaki

Year: 2017

Venue: Gerontology

DOI: https://doi.org/10.1159/000450945

Paper Ex vivo Anti-Senescence Activity of N-Acetylcysteine in Visceral Adipose Tissue of Obese Volunteers

Diba Behtaj; A. Ghorbani; G. Eslamian et al. · 2024 · Obesity Facts · DOI

Full title: Ex vivo Anti-Senescence Activity of N-Acetylcysteine in Visceral Adipose Tissue of Obese Volunteers

Authors: Diba Behtaj; A. Ghorbani; G. Eslamian; Nasser Malekpour Alamdari; Maryam Abbasi; H. Zand; Azam Shakery; Ghazaleh Shimi; M. Sohouli; Sepideh Fazeli Taherian

Year: 2024

Venue: Obesity Facts

DOI: https://doi.org/10.1159/000539255

Paper Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review.

Austad, Steven N; Bartke, Andrzej · 2015 · Gerontology · DOI

Full title: Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review.

Authors: Austad, Steven N; Bartke, Andrzej

Year: 2015

Venue: Gerontology

DOI: https://doi.org/10.1159/000381472

Paper Effect of somatostatin-28 on growth hormone response to growth hormone-releasing hormone--impact of aging and lifelong dietary restriction.

I. Shimokawa; Y. Higami; T. Okimoto et al. · 1997 · Neuroendocrinology · DOI

Full title: Effect of somatostatin-28 on growth hormone response to growth hormone-releasing hormone--impact of aging and lifelong dietary restriction.

Authors: I. Shimokawa; Y. Higami; T. Okimoto; M. Tomita; T. Ikeda

Year: 1997

Venue: Neuroendocrinology

DOI: https://doi.org/10.1159/000127197

Paper Are Senolytic Agents Guilty of Overkill or Inappropriate Age Discrimination?

Rabinovitch, Marlene · 2023 · Circulation · DOI

Full title: Are Senolytic Agents Guilty of Overkill or Inappropriate Age Discrimination?

Authors: Rabinovitch, Marlene

Year: 2023

Venue: Circulation

DOI: https://doi.org/10.1161/CIRCULATIONAHA.122.060247

Paper Elixir of Life

Beyret, Ergin; Redondo, Paloma Martinez; Platero-Luengo, Aida et al. · 2018 · Circulation Research · DOI

Full title: Elixir of Life

Authors: Beyret, Ergin; Redondo, Paloma Martinez; Platero-Luengo, Aida; Belmonte, Juan Carlos Izpisúa

Year: 2018

Venue: Circulation Research

DOI: https://doi.org/10.1161/circresaha.117.311866

Paper Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular Diseases

Kane, Alice E.; Sinclair, David · 2018 · Circulation Research · DOI

Full title: Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular Diseases

Authors: Kane, Alice E.; Sinclair, David

Year: 2018

Venue: Circulation Research

DOI: https://doi.org/10.1161/circresaha.118.312498

Paper Can Metformin Downshift the Gears of Aging to Slow Emphysema Progression?

I. Petrache; K. Serban · 2021 · American Journal of Respiratory and Critical Care Medicine · DOI

Full title: Can Metformin Downshift the Gears of Aging to Slow Emphysema Progression?

Authors: I. Petrache; K. Serban

Year: 2021

Venue: American Journal of Respiratory and Critical Care Medicine

DOI: https://doi.org/10.1164/rccm.202105-1273ed

Paper Оценка геропротекторного эффекта микрогидрина и его влияния на темпы биологического старения работников Северомуйского тоннеля

Шевченко Оксана Ивановна; Кодинец Ирина Николаевна; Катаманова Елена Владимировна et al. · 2011 · DOI

Full title: Оценка геропротекторного эффекта микрогидрина и его влияния на темпы биологического старения работников Северомуйского тоннеля

Authors: Шевченко Оксана Ивановна; Кодинец Ирина Николаевна; Катаманова Елена Владимировна; Лахман Олег Леонидович

Year: 2011

DOI: https://doi.org/10.18370/2309-4117.2021.59.78-82

Paper Calorie restriction protects neural stem cells from age-related deficits in the subventricular zone

Deana M. Apple; Swetha Mahesula; R. S. Fonseca et al. · 2019 · Aging · DOI

Full title: Calorie restriction protects neural stem cells from age-related deficits in the subventricular zone

Authors: Deana M. Apple; Swetha Mahesula; R. S. Fonseca; Chang Zhu; Erzsebet Kokovay

Year: 2019

Venue: Aging

DOI: https://doi.org/10.18632/aging.101731

Paper No limit to maximal lifespan in humans: how to beat a 122-year-old record.

Blagosklonny, Mikhail V · 2021 · Oncoscience · DOI

Full title: No limit to maximal lifespan in humans: how to beat a 122-year-old record.

Authors: Blagosklonny, Mikhail V

Year: 2021

Venue: Oncoscience

DOI: https://doi.org/10.18632/oncoscience.547

Paper Untitled

Blagosklonny, Mikhail V., Blagosklonny, M, Blagosklonny, M, Keaney, M, Gems, D, Doonan, R, Mcelwee, J, Matthijssens, F, Walker, G, Houthoofd, K, Back, P, Matscheski, A, Vanfleteren, J, Gems, D, Perez, V, Bokov, A, Remmen, H Van, Mele, J, Ran, Q, Ikeno, Y, Richardson, A, Ristow, M, Schmeisser, S, Ristow, M, Schmeisser, K, Raamsdonk, J Van, Hekimi, S, Blagosklonny, M, Gems, D, Guardia, Y De La, Selman, C, Mclaren, J, Collins, A, Duthie, G, Speakman, J, Selman, C, Mclaren, J, Meyer, C, Duncan, J, Redman, P, Collins, A, Duthie, G, Speakman, J, Bjelakovic, G, Nikolova, D, Gluud, L, Simonetti, R, Gluud, C, Bjelakovic, G, Nikolova, D, Gluud, C, Omenn, G, Goodman, G, Thornquist, M, Balmes, J, Cullen, M, Glass, A, Keogh, J, Meyskens, F, Valanis, B, Williams, J, Barnhart, S, Hammar, S, Goodman, G, Thornquist, M, Balmes, J, Cullen, M, Meyskens, F, Jr, Omenn, G, Valanis, B, Williams, J, Wright, M, Virtamo, J, Hartman, A, Pietinen, P, Edwards, B, Taylor, P, Huttunen, J, Albanes, D, Sayin, V, Ibrahim, M, Larsson, E, Nilsson, J, Lindahl, P, Bergo, M, Piskounova, E, Agathocleous, M, Murphy, M, Hu, Z, Huddlestun, S, Zhao, Z, Leitch, A, Johnson, T, Deberardinis, R, Morrison, S, Blagosklonny, M, Blagosklonny, M, Blagosklonny, M, Burch, J · 2021 · Oncotarget · DOI

Full title: Untitled

Authors: Blagosklonny, Mikhail V., Blagosklonny, M, Blagosklonny, M, Keaney, M, Gems, D, Doonan, R, Mcelwee, J, Matthijssens, F, Walker, G, Houthoofd, K, Back, P, Matscheski, A, Vanfleteren, J, Gems, D, Perez, V, Bokov, A, Remmen, H Van, Mele, J, Ran, Q, Ikeno, Y, Richardson, A, Ristow, M, Schmeisser, S, Ristow, M, Schmeisser, K, Raamsdonk, J Van, Hekimi, S, Blagosklonny, M, Gems, D, Guardia, Y De La, Selman, C, Mclaren, J, Collins, A, Duthie, G, Speakman, J, Selman, C, Mclaren, J, Meyer, C, Duncan, J, Redman, P, Collins, A, Duthie, G, Speakman, J, Bjelakovic, G, Nikolova, D, Gluud, L, Simonetti, R, Gluud, C, Bjelakovic, G, Nikolova, D, Gluud, C, Omenn, G, Goodman, G, Thornquist, M, Balmes, J, Cullen, M, Glass, A, Keogh, J, Meyskens, F, Valanis, B, Williams, J, Barnhart, S, Hammar, S, Goodman, G, Thornquist, M, Balmes, J, Cullen, M, Meyskens, F, Jr, Omenn, G, Valanis, B, Williams, J, Wright, M, Virtamo, J, Hartman, A, Pietinen, P, Edwards, B, Taylor, P, Huttunen, J, Albanes, D, Sayin, V, Ibrahim, M, Larsson, E, Nilsson, J, Lindahl, P, Bergo, M, Piskounova, E, Agathocleous, M, Murphy, M, Hu, Z, Huddlestun, S, Zhao, Z, Leitch, A, Johnson, T, Deberardinis, R, Morrison, S, Blagosklonny, M, Blagosklonny, M, Blagosklonny, M, Burch, J

Year: 2021

Venue: Oncotarget

DOI: https://doi.org/10.18632/oncotarget.v12i3

Paper Ghrelin receptor controls obesity by fat burning

Yuxiang Sun · 2015 · OncoTarget · DOI

Full title: Ghrelin receptor controls obesity by fat burning

Authors: Yuxiang Sun

Year: 2015

Venue: OncoTarget

DOI: https://doi.org/10.18632/oncotarget.3668

Paper An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies

Perri, Giorgia; French, Chloe; Agostinis‐Sobrinho, César et al. · 2024 · The Journals of Gerontology Series A · DOI

Full title: An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies

Authors: Perri, Giorgia; French, Chloe; Agostinis‐Sobrinho, César; Anand, Atul; Antarianto, Radiana Dhewayani; Arai, Yasumichi; Baur, Joseph A.; Cauli, Omar; Clivaz-Duc, Morgane; Colloca, Giuseppe; Demetriades, Constantinos; Lucia, Chiara de; Gessa, Giorgio Di; Diniz, Breno S.; Dotchin, Catherine; Eaglestone, Gillian; Elliott, Bradley; Espeland, Mark A.; Ferrucci, Luigi; Fisher, James T.; Grammatopoulos, Dimitris; Hardiany, Novi Silvia; Hassan‐Smith, Zaki; Hastings, Waylon J.; Jain, Swati; Joshi, Peter K.; Κάτσιλα, Θεοδώρα; Kemp, Graham J.; Khaiyat, Omid; Lamming, Dudley W.; Lara, José; Madeo, Frank; Maier, Andrea B.; Martín-Ruiz, Carmen; Martins, Ian; Mathers, John C.; Mattin, Lewis; Merchant, Reshma Aziz; Moskalev, Alexey; Neytchev, Ognian; Lochlainn, Mary Ní; Owen, Claire M.; Phillips, Stuart M.; Pratt, Jedd; Prokopidis, Konstantinos; Rattray, Nicholas J. W.; Rúa-Alonso, María; Schomburg, Lutz; Scott, David; Shyam, Sangeetha; Sillanpää, Elina; Tan, Michelle M. C.; Teh, Ruth; Tobin, Stephanie W.; Vila‐Chã, Carolina; Vorluni, Luigi; Weber, Daniela; Welch, Ailsa; Wilson, Daisy; Wilson, Thomas; Zhao, Tongbiao; Philippou, Elena; Korolchuk, Viktor I.; Shannon, Oliver M.

Year: 2024

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glae297

Paper Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program.

Jiang, Nisi; Xu, Ziying; Zhao, Shangang et al. · 2025 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program.

Authors: Jiang, Nisi; Xu, Ziying; Zhao, Shangang; Gelfond, Jonathan; Strong, Randy; Nelson, James F

Year: 2025

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glaf138

Paper Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis

Daniel W Belsky; K. Huffman; C. Pieper et al. · 2017 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis

Authors: Daniel W Belsky; K. Huffman; C. Pieper; I. Shalev; W. Kraus

Year: 2017

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glx096

Paper Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes

Justice, Jamie N.; Miller, Jordan D.; Newman, John C. et al. · 2016 · The Journals of Gerontology Series A · DOI

Full title: Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes

Authors: Justice, Jamie N.; Miller, Jordan D.; Newman, John C.; Hashmi, Shahrukh K.; Halter, Jeffrey B.; Austad, Steve; Barzilai, Nir; Kirkland, James L.

Year: 2016

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glw126

Paper Multiomic clocks to predict phenotypic age in mice.

Vera, Daniel L; Griffin, Patrick T; Leigh, David et al. · 2025 · bioRxiv : the preprint server for biology · DOI

Full title: Multiomic clocks to predict phenotypic age in mice.

Authors: Vera, Daniel L; Griffin, Patrick T; Leigh, David; Kras, Jason; Ramos, Enrique; Bishof, Isaac; Butler, Anderson; Chwalek, Karolina; Vogel, David S; Kane, Alice E; Sinclair, David A

Year: 2025

Venue: bioRxiv : the preprint server for biology

DOI: https://doi.org/10.1101/2025.04.30.651114

Paper Senolytics Enhance the Longevity of Caenorhabditis elegans by Altering Betaine Metabolism.

Lan, Wenning; Xiao, Xiaolian; Nian, Jingjing et al. · 2024 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Senolytics Enhance the Longevity of Caenorhabditis elegans by Altering Betaine Metabolism.

Authors: Lan, Wenning; Xiao, Xiaolian; Nian, Jingjing; Wang, Ziran; Zhang, Xiaojing; Wu, Yajiao; Zhang, Dongcheng; Chen, Junkun; Bao, Wenqiang; Li, Chutao; Zhang, Yun; Zhu, An; Zhang, Fangrong

Year: 2024

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glae221

Paper Resilience in Aging Mice

Kirkland, James L.; Stout, Michael B.; Sierra, Felipe · 2016 · The Journals of Gerontology Series A · DOI

Full title: Resilience in Aging Mice

Authors: Kirkland, James L.; Stout, Michael B.; Sierra, Felipe

Year: 2016

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glw086

Paper Caloric Restriction and Healthy Life Span: Frail Phenotype of Nonhuman Primates in the Wisconsin National Primate Research Center Caloric Restriction Study

Yamada, Yosuke; Kemnitz, Joseph W.; Weindruch, Richard et al. · 2017 · The Journals of Gerontology Series A · DOI

Full title: Caloric Restriction and Healthy Life Span: Frail Phenotype of Nonhuman Primates in the Wisconsin National Primate Research Center Caloric Restriction Study

Authors: Yamada, Yosuke; Kemnitz, Joseph W.; Weindruch, Richard; Anderson, Rozalyn M.; Schoeller, Dale A.; Colman, Ricki J.

Year: 2017

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glx059

Paper Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index.

Kane, Alice E; Hilmer, Sarah N; Boyer, Dawn et al. · 2016 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index.

Authors: Kane, Alice E; Hilmer, Sarah N; Boyer, Dawn; Gavin, Kristan; Nines, Dawn; Howlett, Susan E; de Cabo, Rafael; Mitchell, Sarah J

Year: 2016

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glu315

Paper Development of a Rat Clinical Frailty Index

Yorke, Amy M.; Kane, Alice E.; Friesen, Camille L. Hancock et al. · 2017 · The Journals of Gerontology Series A · DOI

Full title: Development of a Rat Clinical Frailty Index

Authors: Yorke, Amy M.; Kane, Alice E.; Friesen, Camille L. Hancock; Howlett, Susan E.; O’Blenes, Stacy B.

Year: 2017

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glw339

Paper Metformin Suppresses Monocyte Inflammation and Metabolic Reprogramming by SARS-CoV-2 Spike Protein

T. Cory; R. Emmons; Johnathan R. Yarbro et al. · 2021 · Innovation in aging · DOI

Full title: Metformin Suppresses Monocyte Inflammation and Metabolic Reprogramming by SARS-CoV-2 Spike Protein

Authors: T. Cory; R. Emmons; Johnathan R. Yarbro; B. Pence

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.1284

Paper Bring Back the Rat!

Carter, Christy S; Richardson, Arlan; Huffman, Derek M et al. · 2020 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Bring Back the Rat!

Authors: Carter, Christy S; Richardson, Arlan; Huffman, Derek M; Austad, Steven

Year: 2020

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glz298

Paper Mechanistic target of rapamycin signaling in mouse models of accelerated aging

Lee, Jin Young; Kennedy, Brian K.; Liao, Chen‐Yu · 2019 · The Journals of Gerontology Series A · DOI

Full title: Mechanistic target of rapamycin signaling in mouse models of accelerated aging

Authors: Lee, Jin Young; Kennedy, Brian K.; Liao, Chen‐Yu

Year: 2019

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glz059

Paper Life-span Extension With Reduced Somatotrophic Signaling: Moderation of Aging Effect by Signal Type, Sex, and Experimental Cohort

Garratt, Michael; Nakagawa, Shinichi; Simons, Mirre J. P. · 2017 · The Journals of Gerontology Series A · DOI

Full title: Life-span Extension With Reduced Somatotrophic Signaling: Moderation of Aging Effect by Signal Type, Sex, and Experimental Cohort

Authors: Garratt, Michael; Nakagawa, Shinichi; Simons, Mirre J. P.

Year: 2017

Venue: The Journals of Gerontology Series A

DOI: https://doi.org/10.1093/gerona/glx010

Paper Can We Simplify Aging?

S. Ukraintseva; A. Yashin · 2021 · Innovation in aging · DOI

Full title: Can We Simplify Aging?

Authors: S. Ukraintseva; A. Yashin

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.2496

Paper Age‐related alterations in gait function in freely moving male C57BL/6 mice: translational relevance of decreased cadence and increased gait variability

S. Tarantini; A. Yabluchanskiy; G. Fulop et al. · 2018 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Age‐related alterations in gait function in freely moving male C57BL/6 mice: translational relevance of decreased cadence and increased gait variability

Authors: S. Tarantini; A. Yabluchanskiy; G. Fulop; T. Kiss; Aleksandra Perz; Daniel O’Connor; Emily Johnson; Farzaneh A. Sorond; Z. Ungvari; A. Csiszar

Year: 2018

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/gly242

Paper CONVERGENT CELL NONAUTONOMOUS PATHWAYS REWIRE METABOLISM TO SLOW AGING

S. Leiser; Shijiao Huang; Hillary A. Miller et al. · 2022 · Innovation in aging · DOI

Full title: CONVERGENT CELL NONAUTONOMOUS PATHWAYS REWIRE METABOLISM TO SLOW AGING

Authors: S. Leiser; Shijiao Huang; Hillary A. Miller; S. Beydoun; Elizabeth S. Dean; H. Choi; A. Bhat; Marshall B. Howington

Year: 2022

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igac059.1733

Paper Role of Physiological Resilience in Aging: Challenges and Opportunities

D. Huffman · 2021 · Innovation in aging · DOI

Full title: Role of Physiological Resilience in Aging: Challenges and Opportunities

Authors: D. Huffman

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.622

Paper Anti-Aging Interventions Targeting the Hallmarks of Aging

Brian Kennedy · 2021 · Innovation in aging · DOI

Full title: Anti-Aging Interventions Targeting the Hallmarks of Aging

Authors: Brian Kennedy

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.1972

Paper Recombinant SARS-CoV-2 Spike Protein Mediates Glycolytic and Inflammatory Activation in Human Monocytes

B. Pence · 2020 · Innovation in aging · DOI

Full title: Recombinant SARS-CoV-2 Spike Protein Mediates Glycolytic and Inflammatory Activation in Human Monocytes

Authors: B. Pence

Year: 2020

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igaa057.3493

Paper Mammalian Co-methylation Network Analysis of Species Characteristics

Haghani, Amin; Horvath, Steve · 2021 · Innovation in Aging · DOI

Full title: Mammalian Co-methylation Network Analysis of Species Characteristics

Authors: Haghani, Amin; Horvath, Steve

Year: 2021

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igab046.2535

Paper ROBUST LONGEVITY EFFECTS OF NOVEL COMPOUNDS TESTED BY THE CAENORHABDITIS INTERVENTION TESTING PROGRAM

M. Driscoll; Brian Onken; Christine A Sedore et al. · 2022 · Innovation in aging · DOI

Full title: ROBUST LONGEVITY EFFECTS OF NOVEL COMPOUNDS TESTED BY THE CAENORHABDITIS INTERVENTION TESTING PROGRAM

Authors: M. Driscoll; Brian Onken; Christine A Sedore; Anna L. Coleman-Hulbert; David Hall; G. Lithgow; P. Phillips; Viviana Perez Montes

Year: 2022

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igac059.2931

Paper COMPARATIVE TRANSCRIPTOMICS AND PROTEOMICS ACROSS SPECIES

Vera Gorbunova · 2023 · Innovation in aging · DOI

Full title: COMPARATIVE TRANSCRIPTOMICS AND PROTEOMICS ACROSS SPECIES

Authors: Vera Gorbunova

Year: 2023

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igad104.1424

Paper DELETION OF THROMBOSPONDIN-1 PRESERVES HEMATOPOIETIC STEM CELL HEALTHSPAN DURING AGING

Ramalingam, Pradeep; Gutkin, Michael; Poulos, Michael G. et al. · 2022 · Innovation in Aging · DOI

Full title: DELETION OF THROMBOSPONDIN-1 PRESERVES HEMATOPOIETIC STEM CELL HEALTHSPAN DURING AGING

Authors: Ramalingam, Pradeep; Gutkin, Michael; Poulos, Michael G.; Butler, Jason M.

Year: 2022

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igac059.2664

Paper STRATEGIES OF LIFESPAN REGULATION WITHIN AND ACROSS SPECIES

Vadim N. Gladyshev · 2023 · Innovation in aging · DOI

Full title: STRATEGIES OF LIFESPAN REGULATION WITHIN AND ACROSS SPECIES

Authors: Vadim N. Gladyshev

Year: 2023

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igad104.1425

Paper LEVERAGING THE NDUFS4-/- MOUSE AS A PLATFORM FOR TESTING LONGEVITY INTERVENTIONS

Alessandro Bitto; Cara Tobey; Ayush Sharma et al. · 2022 · Innovation in aging · DOI

Full title: LEVERAGING THE NDUFS4-/- MOUSE AS A PLATFORM FOR TESTING LONGEVITY INTERVENTIONS

Authors: Alessandro Bitto; Cara Tobey; Ayush Sharma; Anthony Grillo; Matt Kaeberlein

Year: 2022

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igac059.2663

Paper - **DOI:** 10.1093/geroni/igad104.0594 - **Authors:** Shin-ichiro Imai - **Year:** 2023 - **Journal:** Innovation in aging

Shin-ichiro Imai · 2023 · Innovation in aging · DOI

Full title: - **DOI:** 10.1093/geroni/igad104.0594 - **Authors:** Shin-ichiro Imai - **Year:** 2023 - **Journal:** Innovation in aging

Authors: Shin-ichiro Imai

Year: 2023

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igad104.0594

Paper ANTIDIABETIC THERAPIES METFORMIN AND TRODUSQUEMINE MODULATE MIRNAS INVOLVED WITH LIVER METABOLISM

Ashiqueali, Sarah; Schneider, Augusto; Zhu, Xiang et al. · 2023 · Innovation in Aging · DOI

Full title: ANTIDIABETIC THERAPIES METFORMIN AND TRODUSQUEMINE MODULATE MIRNAS INVOLVED WITH LIVER METABOLISM

Authors: Ashiqueali, Sarah; Schneider, Augusto; Zhu, Xiang; Juszczyk, Ewelena; Zhu, Yun; Bartke, Andrzej; Siddiqi, Shadab A.; Masternak, Michał M.

Year: 2023

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igad104.1813

Paper ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

M. Driscoll; Brian Onken; Yunpeng Xu et al. · 2022 · Innovation in aging · DOI

Full title: ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

Authors: M. Driscoll; Brian Onken; Yunpeng Xu; Yuhua Song; Madhuri Achanta; Christine A Sedore; P. Phillips; G. Lithgow

Year: 2022

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igac059.2908

Paper Can We Simplify Aging?

S. Ukraintseva; A. Yashin · 2021 · Innovation in aging · DOI

Full title: Can We Simplify Aging?

Authors: S. Ukraintseva; A. Yashin

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.2496

Paper PERIODIC FASTING MIMICKING DIET, LONGEVITY, AND DISEASE

V. Longo · 2022 · Innovation in aging · DOI

Full title: PERIODIC FASTING MIMICKING DIET, LONGEVITY, AND DISEASE

Authors: V. Longo

Year: 2022

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igac059.362

Paper MULTIOMIC SYSTEMS ANALYSIS OF LIFESPAN-EXTENDING INTERVENTIONS IN MOUSE TISSUES

Watanabe, Kengo; Wilmanski, Tomasz; Baloni, Priyanka et al. · 2023 · Innovation in Aging · DOI

Full title: MULTIOMIC SYSTEMS ANALYSIS OF LIFESPAN-EXTENDING INTERVENTIONS IN MOUSE TISSUES

Authors: Watanabe, Kengo; Wilmanski, Tomasz; Baloni, Priyanka; Robinson, Max; Fiehn, Oliver; Moritz, Robert L.; Miller, Richard A.; Rappaport, Noa

Year: 2023

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igad104.3000

Paper The Impact of Short-Term Dietary Restriction on Stem Cell Function

A. Unnikrishnan · 2021 · Innovation in aging · DOI

Full title: The Impact of Short-Term Dietary Restriction on Stem Cell Function

Authors: A. Unnikrishnan

Year: 2021

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igab046.443

Paper Interconnections of Hypoxia and Aging in Long-Lived Species

Damla Yalcin; Hsin-Yu Fang; Erdogan Oguzhan Akyildiz et al. · 2025 · Innovation in aging · DOI

Full title: Interconnections of Hypoxia and Aging in Long-Lived Species

Authors: Damla Yalcin; Hsin-Yu Fang; Erdogan Oguzhan Akyildiz; Sudenaz Fatma Oner; A. Dogan; Thomas Park; Perinur Bozaykut Eker

Year: 2025

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igaf122.2882

Paper FROM THE NATHAN SHOCK CENTERS COORDINATING CENTER: BIOLOGY OF AGING FOR NONBIOLOGISTS

Odette van der Willik; Steven Austad · 2024 · Innovation in aging · DOI

Full title: FROM THE NATHAN SHOCK CENTERS COORDINATING CENTER: BIOLOGY OF AGING FOR NONBIOLOGISTS

Authors: Odette van der Willik; Steven Austad

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.1906

Paper MAPPING LONGEVITY PATHWAYS THROUGH MITOCHONDRIAL DYSFUNCTION: ROLES OF THE MICROBIOME AND METABOLISM IN AGING

Bitto, Alessandro · 2024 · Innovation in Aging · DOI

Full title: MAPPING LONGEVITY PATHWAYS THROUGH MITOCHONDRIAL DYSFUNCTION: ROLES OF THE MICROBIOME AND METABOLISM IN AGING

Authors: Bitto, Alessandro

Year: 2024

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igae098.2627

Paper THE CONTRIBUTION OF THE MICROBIOME TO THE AGING PROCESS

D. Valenzano · 2024 · Innovation in aging · DOI

Full title: THE CONTRIBUTION OF THE MICROBIOME TO THE AGING PROCESS

Authors: D. Valenzano

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.1911

Paper SEROTONIN AND DOPAMINE CIRCUITS MODULATE AGING IN RESPONSE TO FOOD CUES AND AVAILABILITY

S. Leiser · 2023 · Innovation in aging · DOI

Full title: SEROTONIN AND DOPAMINE CIRCUITS MODULATE AGING IN RESPONSE TO FOOD CUES AND AVAILABILITY

Authors: S. Leiser

Year: 2023

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igad104.3001

Paper FMO-4 SLOWS AGING DOWNSTREAM OF MTOR AND DR THROUGH ER TO MITOCHONDRIA CALCIUM SIGNALING

Angela M Tuckowski; S. Beydoun; Elizabeth S. Kitto et al. · 2024 · Innovation in aging · DOI

Full title: FMO-4 SLOWS AGING DOWNSTREAM OF MTOR AND DR THROUGH ER TO MITOCHONDRIA CALCIUM SIGNALING

Authors: Angela M Tuckowski; S. Beydoun; Elizabeth S. Kitto; Ajay Bhat; Marshall B. Howington; A. Sridhar; M. Bhandari; K. Chambers; S. Leiser

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.1719

Paper NEW TOOL ENHANCES DETECTION OF LIFE-EXTENDING INTERVENTIONS BY DELINEATING THEIR TEMPORAL EFFICACY

Edward Miller; Marc A Cohen; Elizabeth Simpson et al. · 2024 · Innovation in aging · DOI

Full title: NEW TOOL ENHANCES DETECTION OF LIFE-EXTENDING INTERVENTIONS BY DELINEATING THEIR TEMPORAL EFFICACY

Authors: Edward Miller; Marc A Cohen; Elizabeth Simpson; Sara Karon; Iara Oliveira; J. Dey; Marie Squillace; J. Bowblis

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.2004

Paper Crowdsourced Drug Discovery Approach Identifies BET Inhibitors As Novel Geroprotectors Promoting Healthy Aging

Byungju Kim; Samuel Beck · 2025 · Innovation in aging · DOI

Full title: Crowdsourced Drug Discovery Approach Identifies BET Inhibitors As Novel Geroprotectors Promoting Healthy Aging

Authors: Byungju Kim; Samuel Beck

Year: 2025

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igaf122.3908

Paper ACCELERATED PACE OF BIOLOGICAL AGING IN PARTICIPANTS WITH LOW LEVELS OF SELENIUM BIOMARKERS IN BERLIN AGING STUDY II

V. Vetter; K. Demircan; Jan Homann et al. · 2024 · Innovation in aging · DOI

Full title: ACCELERATED PACE OF BIOLOGICAL AGING IN PARTICIPANTS WITH LOW LEVELS OF SELENIUM BIOMARKERS IN BERLIN AGING STUDY II

Authors: V. Vetter; K. Demircan; Jan Homann; M. Mülleder; M. Ralser; Lars Bertram; L. Schomburg; I. Demuth

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.2617

Paper When What You See Isn’t What You Get: How Environmental Cues Modify Longevity and Behavior

Scott Leiser · 2025 · Innovation in aging · DOI

Full title: When What You See Isn’t What You Get: How Environmental Cues Modify Longevity and Behavior

Authors: Scott Leiser

Year: 2025

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igaf122.967

Paper NEW TOOL ENHANCES DETECTION OF LIFE-EXTENDING INTERVENTIONS BY DELINEATING THEIR TEMPORAL EFFICACY

Edward Miller; Marc A Cohen; Elizabeth Simpson et al. · 2024 · Innovation in aging · DOI

Full title: NEW TOOL ENHANCES DETECTION OF LIFE-EXTENDING INTERVENTIONS BY DELINEATING THEIR TEMPORAL EFFICACY

Authors: Edward Miller; Marc A Cohen; Elizabeth Simpson; Sara Karon; Iara Oliveira; J. Dey; Marie Squillace; J. Bowblis

Year: 2024

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igae098.2004

Paper POSTTRANSLATIONAL MODULATION OF MACROMOLECULES DURING AGING

Bertolotti, Anne; Cuervo, Ana María · 2017 · Innovation in Aging · DOI

Full title: POSTTRANSLATIONAL MODULATION OF MACROMOLECULES DURING AGING

Authors: Bertolotti, Anne; Cuervo, Ana María

Year: 2017

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igx004.3360

Paper Targeting Vascular Aging in Progeria by mTOR Inhibitors from Multi-Omics Screening

Hsin-Yu Fang; Helin Sera Şan; Fatma Akar et al. · 2025 · Innovation in aging · DOI

Full title: Targeting Vascular Aging in Progeria by mTOR Inhibitors from Multi-Omics Screening

Authors: Hsin-Yu Fang; Helin Sera Şan; Fatma Akar; Sudenaz Fatma Oner; Ceren Şinikçi; A. Tyshkovskiy; Vadim N. Gladyshev; Perinur Bozaykut Eker

Year: 2025

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igaf122.3850

Paper MECHANISMS OF LONGEVITY: LESSONS FROM LONG-LIVED MAMMALS

V. Gorbunova · 2019 · Innovation in aging · DOI

Full title: MECHANISMS OF LONGEVITY: LESSONS FROM LONG-LIVED MAMMALS

Authors: V. Gorbunova

Year: 2019

Venue: Innovation in aging

DOI: https://doi.org/10.1093/geroni/igz038.026

Paper THE MOUSE CLINICAL FRAILTY INDEX AS AN OUTCOME AND MODULATOR OF DRUG THERAPY

S. Howlett · 2017 · Innovation in Aging · DOI

Full title: THE MOUSE CLINICAL FRAILTY INDEX AS AN OUTCOME AND MODULATOR OF DRUG THERAPY

Authors: S. Howlett

Year: 2017

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igx004.3794

Paper Anti-aging medicine: can consumers be better protected?

Mehlman, Maxwell J; Binstock, Robert H; Juengst, Eric T et al. · 2004 · The Gerontologist · DOI

Full title: Anti-aging medicine: can consumers be better protected?

Authors: Mehlman, Maxwell J; Binstock, Robert H; Juengst, Eric T; Ponsaran, Roselle S; Whitehouse, Peter J

Year: 2004

Venue: The Gerontologist

DOI: https://doi.org/10.1093/geront/44.3.304

Paper FRAILTY AND BIOLOGICAL AGE IN ANIMAL MODELS

Howlett, Susan E. · 2018 · Innovation in Aging · DOI

Full title: FRAILTY AND BIOLOGICAL AGE IN ANIMAL MODELS

Authors: Howlett, Susan E.

Year: 2018

Venue: Innovation in Aging

DOI: https://doi.org/10.1093/geroni/igy023.3115

Paper Unraveling the metabolic heterogeneity and commonality in senescent cells using systems modeling.

Li, Gong-Hua; Li, Yu-Hong; Yu, Qin et al. · 2025 · Life medicine · DOI

Full title: Unraveling the metabolic heterogeneity and commonality in senescent cells using systems modeling.

Authors: Li, Gong-Hua; Li, Yu-Hong; Yu, Qin; Zhou, Qing-Qing; Zhang, Run-Feng; Weng, Chong-Jun; Ge, Ming-Xia; Kong, Qing-Peng

Year: 2025

Venue: Life medicine

DOI: https://doi.org/10.1093/lifemedi/lnaf003

Paper #2330 Fisetin supplement ameliorates aging related changes in the kidney

P. Fu; Qian Ren; Hui Li et al. · 2024 · Nephrology, Dialysis and Transplantation · DOI

Full title: #2330 Fisetin supplement ameliorates aging related changes in the kidney

Authors: P. Fu; Qian Ren; Hui Li; Liang Ma

Year: 2024

Venue: Nephrology, Dialysis and Transplantation

DOI: https://doi.org/10.1093/ndt/gfae069.708

Paper OLD AGE PHARMACOEPIDEMIOLOGY: SETTING THE SCENE

K. Johnell · 2017 · DOI

Full title: OLD AGE PHARMACOEPIDEMIOLOGY: SETTING THE SCENE

Authors: K. Johnell

Year: 2017

DOI: https://doi.org/10.1093/geroni/igx004.3791

Paper Metabolic regulation in the senescence process of stem cells.

Wei, YingYing; Zhang, Bin; Bie, Qingli et al. · 2025 · Stem cells translational medicine · DOI

Full title: Metabolic regulation in the senescence process of stem cells.

Authors: Wei, YingYing; Zhang, Bin; Bie, Qingli; He, Baoyu

Year: 2025

Venue: Stem cells translational medicine

DOI: https://doi.org/10.1093/stcltm/szaf041

Paper AgeAnnoMO: a knowledgebase of multi-omics annotation for animal aging.

Huang, Kexin; Liu, Xi; Zhang, Zhaocan et al. · 2024 · Nucleic acids research · DOI

Full title: AgeAnnoMO: a knowledgebase of multi-omics annotation for animal aging.

Authors: Huang, Kexin; Liu, Xi; Zhang, Zhaocan; Wang, Tiangang; Xu, Haixia; Li, Qingxuan; Jia, Yuhao; Huang, Liyu; Kim, Pora; Zhou, Xiaobo

Year: 2024

Venue: Nucleic acids research

DOI: https://doi.org/10.1093/nar/gkad884

Paper Decelerated Aging: Should I Drink from a Fountain of Youth?

Post, Stephen G. · 2004 · DOI

Full title: Decelerated Aging: Should I Drink from a Fountain of Youth?

Authors: Post, Stephen G.

Year: 2004

DOI: https://doi.org/10.1093/oso/9780195170085.003.0004

Paper Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging.

Sun, Yu; Li, Qingfeng; Kirkland, James L · 2022 · Life medicine · DOI

Full title: Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging.

Authors: Sun, Yu; Li, Qingfeng; Kirkland, James L

Year: 2022

Venue: Life medicine

DOI: https://doi.org/10.1093/lifemedi/lnac030

Paper Endurance Exercise and Selective Breeding for Longevity Extend Drosophila Healthspan by Overlapping Mechanisms

Sujkowski, Alyson; Bazzell, Brian; Carpenter, Kylie et al. · 2015 · The FASEB Journal · DOI

Full title: Endurance Exercise and Selective Breeding for Longevity Extend Drosophila Healthspan by Overlapping Mechanisms

Authors: Sujkowski, Alyson; Bazzell, Brian; Carpenter, Kylie; Arking, Robert; Wessells, Robert

Year: 2015

Venue: The FASEB Journal

DOI: https://doi.org/10.1096/fasebj.29.1_supplement.665.14

Paper Inhibition of Ectopic Adipocyte Accretion within Aging Thymic Environment Stimulates Thymopoiesis

V. Dixit; Y. Youm; J. Rim et al. · 2008 · The FASEB Journal · DOI

Full title: Inhibition of Ectopic Adipocyte Accretion within Aging Thymic Environment Stimulates Thymopoiesis

Authors: V. Dixit; Y. Youm; J. Rim; Yuxiang Sun; Roy G. Smith; Steven R Smith; Chiaki Nakata

Year: 2008

Venue: The FASEB Journal

DOI: https://doi.org/10.1096/fasebj.22.1_supplement.845.7

Paper Targeting Alternative Splicing for Reversal of Cellular Senescence in the Context of Aesthetic Aging.

Laura R Bramwell; L. Harries · 2021 · Plastic and Reconstructive Surgery · DOI

Full title: Targeting Alternative Splicing for Reversal of Cellular Senescence in the Context of Aesthetic Aging.

Authors: Laura R Bramwell; L. Harries

Year: 2021

Venue: Plastic and Reconstructive Surgery

DOI: https://doi.org/10.1097/prs.0000000000007618

Paper Emerging strategies for biological age reversal

Bohan, Zhang, · 2022 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: Emerging strategies for biological age reversal

Authors: Bohan, Zhang,

Year: 2022

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper Geroprotectors: A role in the treatment of frailty.

Trendelenburg, A U; Scheuren, A C; Potter, P et al. · 2019 · Mechanisms of ageing and development · DOI

Full title: Geroprotectors: A role in the treatment of frailty.

Authors: Trendelenburg, A U; Scheuren, A C; Potter, P; Müller, R; Bellantuono, I

Year: 2019

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2019.03.002

Paper Exploring vascular aging in ERCC1-deficient mice and progressing toward human vessel-on-a-chip models

Linden, Janette van der · 2026 · EUR Research Repository (Erasmus University Rotterdam)

Full title: Exploring vascular aging in ERCC1-deficient mice and progressing toward human vessel-on-a-chip models

Authors: Linden, Janette van der

Year: 2026

Venue: EUR Research Repository (Erasmus University Rotterdam)

Paper [Geroprotectors: specific action or hormesis?].

Vaĭserman, A M · 2008 · Advances in gerontology = Uspekhi gerontologii

Full title: [Geroprotectors: specific action or hormesis?].

Authors: Vaĭserman, A M

Year: 2008

Venue: Advances in gerontology = Uspekhi gerontologii

Paper Grant Title: Effects of Calorie Restriction on Markers of Aging and Longevity Grant Dates: 00/00/00-00/00/00

L. Fontana · 2009

Full title: Grant Title: Effects of Calorie Restriction on Markers of Aging and Longevity Grant Dates: 00/00/00-00/00/00

Authors: L. Fontana

Year: 2009

Paper Effects of dietary and pharmacological anti-aging intervention on adult rats.

G. Cavallini; A. Donati; L. Marinis et al. · 2011 · CINECA IRIS Institutial research information system (University of Pisa)

Full title: Effects of dietary and pharmacological anti-aging intervention on adult rats.

Authors: G. Cavallini; A. Donati; L. Marinis; F. Favorito; E. Bergamini

Year: 2011

Venue: CINECA IRIS Institutial research information system (University of Pisa)

Paper Immortal beloved and beleaguered: towards the integration of the law on assisted death and the scientific pursuit of life extension.

Mary J. Shariff · 2010 · Health law in Canada

Full title: Immortal beloved and beleaguered: towards the integration of the law on assisted death and the scientific pursuit of life extension.

Authors: Mary J. Shariff

Year: 2010

Venue: Health law in Canada

Paper Induction of cellular stress responses by phytochemicals for nutritional applications toward anti-aging intervention

C. Lima; A. Carvalho; A. Gomes et al. · 2011 · RepositóriUM (Universidade do Minho)

Full title: Induction of cellular stress responses by phytochemicals for nutritional applications toward anti-aging intervention

Authors: C. Lima; A. Carvalho; A. Gomes; C. Wilson; Suresh I. S. Rattan

Year: 2011

Venue: RepositóriUM (Universidade do Minho)

Paper Ischemic preconditioning in the younger and aged heart.

Abete, Pasquale; Testa, Gianluca; Cacciatore, Francesco et al. · 2011 · Aging and disease

Full title: Ischemic preconditioning in the younger and aged heart.

Authors: Abete, Pasquale; Testa, Gianluca; Cacciatore, Francesco; Della-Morte, David; Galizia, Gianluigi; Langellotto, Assunta; Rengo, Franco

Year: 2011

Venue: Aging and disease

Paper Mechanisms linking pre-mRNA splicing to longevity in C. elegans

Camila, Perez Matos, Maria · 2025 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: Mechanisms linking pre-mRNA splicing to longevity in C. elegans

Authors: Camila, Perez Matos, Maria

Year: 2025

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper Kinetics and free-radical mechanisms of ageing and carcinogenesis.

Emanuel, N M · 1985 · IARC scientific publications

Full title: Kinetics and free-radical mechanisms of ageing and carcinogenesis.

Authors: Emanuel, N M

Year: 1985

Venue: IARC scientific publications

Paper Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

T, Griffin, Patrick · 2023 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Authors: T, Griffin, Patrick

Year: 2023

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper Induction of antioxidant defenses by diterpenic phenolics in human fibroblasts for nutritional applications toward anti-aging interventions

A. Carvalho; A. Gomes; C. Wilson et al. · 2011 · RepositóriUM (Universidade do Minho)

Full title: Induction of antioxidant defenses by diterpenic phenolics in human fibroblasts for nutritional applications toward anti-aging interventions

Authors: A. Carvalho; A. Gomes; C. Wilson; C. Lima

Year: 2011

Venue: RepositóriUM (Universidade do Minho)

Paper Intermittent Fasting (IF) Promotes Longevity through Alterations of the Mammalian Target of Rapamycin (mTOR) and the Epigenome

Boeckholt, Tayt · 2020 · Open PRAIRIE (South Dakota State University)

Full title: Intermittent Fasting (IF) Promotes Longevity through Alterations of the Mammalian Target of Rapamycin (mTOR) and the Epigenome

Authors: Boeckholt, Tayt

Year: 2020

Venue: Open PRAIRIE (South Dakota State University)

Paper [Models and methods of evaluation of geroprotective activity of pharmacological drugs].

Anisimov, V N; Zabezhinskiĭ, M A; Popovich, I G · 2009 · Advances in gerontology = Uspekhi gerontologii

Full title: [Models and methods of evaluation of geroprotective activity of pharmacological drugs].

Authors: Anisimov, V N; Zabezhinskiĭ, M A; Popovich, I G

Year: 2009

Venue: Advances in gerontology = Uspekhi gerontologii

Paper Biomarkers of aging for the identiﬁcation and evaluation of longevity interventions

M. Moqri; Chiara Herzog; J. Poganik et al.

Full title: Biomarkers of aging for the identiﬁcation and evaluation of longevity interventions

Authors: M. Moqri; Chiara Herzog; J. Poganik; D. Belsky; A. Higgins-Chen; Alexey Moskalev; Georg Fuellen; Alan A. Cohen; I. Bautmans; Martin Widschwendter; Jingzhong Ding; Alexander Fleming; Joan Mannick; J. J. Han; A. Zhavoronkov; N. Barzilai; M. Kaeberlein; Steven R Cummings; Brian K. Kennedy; Luigi Ferrucci; Steve Horvath; Eric Verdin; Andrea B Maier; Michael P. Snyder; V. Sebastiano; Vadim N Gladyshev

Paper MIT Open Access Articles NAD+ and sirtuins in aging and disease

S. Imai; Leonard Guarente

Full title: MIT Open Access Articles NAD+ and sirtuins in aging and disease

Authors: S. Imai; Leonard Guarente

Paper [Metformin reduces the signs of sarcopenia in old OXYS rats].

Kolosova, N G; Vitovtov, A O; Stefanova, N A · 2015 · Advances in gerontology = Uspekhi gerontologii

Full title: [Metformin reduces the signs of sarcopenia in old OXYS rats].

Authors: Kolosova, N G; Vitovtov, A O; Stefanova, N A

Year: 2015

Venue: Advances in gerontology = Uspekhi gerontologii

Paper Peroxiredoxins in Redox Signaling and Aging

Friederike Roger · 2017 · Gothenburg University Publications Electronic Archive (Gothenburg University)

Full title: Peroxiredoxins in Redox Signaling and Aging

Authors: Friederike Roger

Year: 2017

Venue: Gothenburg University Publications Electronic Archive (Gothenburg University)

Paper [Regression of survivability variance upon cohort age in Drosophila melanogaster. II: Effects of geroprotective influences.].

Mylnikov, S V · 2018 · Advances in gerontology = Uspekhi gerontologii

Full title: [Regression of survivability variance upon cohort age in Drosophila melanogaster. II: Effects of geroprotective influences.].

Authors: Mylnikov, S V

Year: 2018

Venue: Advances in gerontology = Uspekhi gerontologii

Paper [Programming of potential longevity in early ontogenesis as a sign of epigenetic adaptation].

Vaĭserman, O M · 2008 · Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)

Full title: [Programming of potential longevity in early ontogenesis as a sign of epigenetic adaptation].

Authors: Vaĭserman, O M

Year: 2008

Venue: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)

Paper [The effect of melatonin on the indices of biological age, on longevity and on the development of spontaneous tumors in mice].

V. Anisimov; N. Zavarzina; M. A. Zabezhinskii et al. · 2000 · Voprosi onkologii

Full title: [The effect of melatonin on the indices of biological age, on longevity and on the development of spontaneous tumors in mice].

Authors: V. Anisimov; N. Zavarzina; M. A. Zabezhinskii; I. Popovich; I. V. Anikin; O. Zimina; M. V. Solov’ev; A. V. Shtylik; A. V. Arutiunian; T. I. Oparina; V. M. Prokopenko; V. Khavinson

Year: 2000

Venue: Voprosi onkologii

Paper Sex dimorphic effects in calorie restriction and CR mimetics on longevity

Baas, Sigrid · 2020

Full title: Sex dimorphic effects in calorie restriction and CR mimetics on longevity

Authors: Baas, Sigrid

Year: 2020

Paper Regulation of Xenobiotic and Bile Acid Metabolism by the Anti-aging Intervention Calorie Restriction in Mice

Z. Fu · 2013 · KU ScholarWorks (The University of Kansas)

Full title: Regulation of Xenobiotic and Bile Acid Metabolism by the Anti-aging Intervention Calorie Restriction in Mice

Authors: Z. Fu

Year: 2013

Venue: KU ScholarWorks (The University of Kansas)

Paper The role of RNA splicing factors in the regulation of longevity

Sneha, Dutta, · 2021 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: The role of RNA splicing factors in the regulation of longevity

Authors: Sneha, Dutta,

Year: 2021

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper The PETase Tournament and Targeting Aging to Treat Disease

W., Blue, Benjamin; Bijoy, Desai, · 2025 · ATE Central (National Science Foundation)

Full title: The PETase Tournament and Targeting Aging to Treat Disease

Authors: W., Blue, Benjamin; Bijoy, Desai,

Year: 2025

Venue: ATE Central (National Science Foundation)

Paper The involvement of macro-autophagy in aging and anti-aging intervention.

E. Bergamini; G. Cavallini; A. Donati et al. · 2005 · CINECA IRIS Institutial research information system (University of Pisa)

Full title: The involvement of macro-autophagy in aging and anti-aging intervention.

Authors: E. Bergamini; G. Cavallini; A. Donati; Z. Gori

Year: 2005

Venue: CINECA IRIS Institutial research information system (University of Pisa)

Paper [The TA-Swiss study on anti-aging medicine].

Stuckelberger, A · 2009 · Revue medicale suisse

Full title: [The TA-Swiss study on anti-aging medicine].

Authors: Stuckelberger, A

Year: 2009

Venue: Revue medicale suisse

Paper Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.

Lamming, Dudley W; Ye, Lan; Astle, Clinton M et al. · 2013 · Aging cell · DOI

Full title: Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.

Authors: Lamming, Dudley W; Ye, Lan; Astle, Clinton M; Baur, Joseph A; Sabatini, David M; Harrison, David E

Year: 2013

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12097

Paper Troubling Implications of Doubling the Human Lifespan.

C. Hackler · 2002

Full title: Troubling Implications of Doubling the Human Lifespan.

Authors: C. Hackler

Year: 2002

Paper Twenty-four – Anti-Aging Medicine and Science: Social Implications

Binstock, Robert H.; Fishman, Jennifer R.; Johnson, Thomas E. · 2006

Full title: Twenty-four – Anti-Aging Medicine and Science: Social Implications

Authors: Binstock, Robert H.; Fishman, Jennifer R.; Johnson, Thomas E.

Year: 2006

Paper Biopolitics Meets Biosemiotics: The Semiotic Thresholds of Anti-Aging Interventions

Ott Puumeister; A. Ventsel · 2018 · Theory Culture & Society · DOI

Full title: Biopolitics Meets Biosemiotics: The Semiotic Thresholds of Anti-Aging Interventions

Authors: Ott Puumeister; A. Ventsel

Year: 2018

Venue: Theory Culture & Society

DOI: https://doi.org/10.1177/0263276416687375

Paper Microrna Mediated Regulation of Hematopoietic Stem Cell Aging

S. Yalcin; Mark Carty; Joseph Y. Shin et al. · 2014 · Blood · DOI

Full title: Microrna Mediated Regulation of Hematopoietic Stem Cell Aging

Authors: S. Yalcin; Mark Carty; Joseph Y. Shin; Richard A. Miller; C. Leslie; Christopher Y. Park

Year: 2014

Venue: Blood

DOI: https://doi.org/10.1182/blood.v124.21.602.602

Paper The use of DNA methylation clock in aging research.

He, Xi; Liu, Jiaojiao; Liu, Bo et al. · 2021 · Experimental biology and medicine (Maywood, N.J.) · DOI

Full title: The use of DNA methylation clock in aging research.

Authors: He, Xi; Liu, Jiaojiao; Liu, Bo; Shi, Jingshan

Year: 2021

Venue: Experimental biology and medicine (Maywood, N.J.)

DOI: https://doi.org/10.1177/1535370220968802

Paper Longevity Promoting Interventions Inhibit Molecular and Functional Changes In Aging Hematopoietic Stem Cells

S. Yalcin; Wenhuo Hu; Richard A. Miller et al. · 2013 · Blood · DOI

Full title: Longevity Promoting Interventions Inhibit Molecular and Functional Changes In Aging Hematopoietic Stem Cells

Authors: S. Yalcin; Wenhuo Hu; Richard A. Miller; Yusup Shin; Christopher Y. Park

Year: 2013

Venue: Blood

DOI: https://doi.org/10.1182/blood.v122.21.1168.1168

Paper An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo.

Lujan, Celia; Tyler, Eleanor Jane; Ecker, Simone et al. · 2024 · Genome medicine · DOI

Full title: An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo.

Authors: Lujan, Celia; Tyler, Eleanor Jane; Ecker, Simone; Webster, Amy Philomena; Stead, Eleanor Rachel; Martinez-Miguel, Victoria Eugenia; Milligan, Deborah; Garbe, James Charles; Stampfer, Martha Ruskin; Beck, Stephan; Lowe, Robert; Bishop, Cleo Lucinda; Bjedov, Ivana

Year: 2024

Venue: Genome medicine

DOI: https://doi.org/10.1186/s13073-024-01349-w

Paper Role of circulating molecules in age-related cardiovascular and metabolic disorders.

Hsiao, Yung Ting; Shimizu, Ippei; Yoshida, Yohko et al. · 2022 · Inflammation and regeneration · DOI

Full title: Role of circulating molecules in age-related cardiovascular and metabolic disorders.

Authors: Hsiao, Yung Ting; Shimizu, Ippei; Yoshida, Yohko; Minamino, Tohru

Year: 2022

Venue: Inflammation and regeneration

DOI: https://doi.org/10.1186/s41232-021-00187-2

Paper Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways.

Ukraintseva, Svetlana V; Yashin, Anatoly I · 2003 · Annals of the New York Academy of Sciences · DOI

Full title: Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways.

Authors: Ukraintseva, Svetlana V; Yashin, Anatoly I

Year: 2003

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1196/annals.1299.089

Paper The Role of Autophagy in Aging

E. Bergamini; G. Cavallini; A. Donati et al. · 2007 · Annals of the New York Academy of Sciences · DOI

Full title: The Role of Autophagy in Aging

Authors: E. Bergamini; G. Cavallini; A. Donati; Z. Gori

Year: 2007

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1196/annals.1396.020

Paper Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction.

Suda, Masayoshi; Paul, Karl H; Tripathi, Utkarsh et al. · 2024 · Endocrine reviews · DOI

Full title: Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction.

Authors: Suda, Masayoshi; Paul, Karl H; Tripathi, Utkarsh; Minamino, Tohru; Tchkonia, Tamara; Kirkland, James L

Year: 2024

Venue: Endocrine reviews

DOI: https://doi.org/10.1210/endrev/bnae010

Paper Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.

Anisimov, Vladimir N; Berstein, Lev M; Popovich, Irina G et al. · 2005 · Annals of the New York Academy of Sciences · DOI

Full title: Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.

Authors: Anisimov, Vladimir N; Berstein, Lev M; Popovich, Irina G; Zabezhinski, Mark A; Egormin, Peter A; Tyndyk, Margarita L; Anikin, Ivan V; Semenchenko, Anna V; Yashin, Anatoli I

Year: 2005

Venue: Annals of the New York Academy of Sciences

DOI: https://doi.org/10.1196/annals.1356.017

Paper HEALTHY AGING

Constantin Munteanu; D. Munteanu · 2013 · DOI

Full title: HEALTHY AGING

Authors: Constantin Munteanu; D. Munteanu

Year: 2013

DOI: https://doi.org/10.12680/978-606-93550-0-8

Paper Reduced metabolic rate after caloric restriction-can we agree on how to normalize the data?

E. Poehlman · 2003 · Journal of Clinical Endocrinology and Metabolism · DOI

Full title: Reduced metabolic rate after caloric restriction-can we agree on how to normalize the data?

Authors: E. Poehlman

Year: 2003

Venue: Journal of Clinical Endocrinology and Metabolism

DOI: https://doi.org/10.1210/jc.2002-021672

Paper Worldwide research on calorie restriction in aging. A bibliometric study

Antonio Fernando Murillo Cancho; David Lozano Paniagua; Francisco Manzano Agugliaro et al. · 2024 · Nutrición clínica y dietética hospitalaria · DOI

Full title: Worldwide research on calorie restriction in aging. A bibliometric study

Authors: Antonio Fernando Murillo Cancho; David Lozano Paniagua; Francisco Manzano Agugliaro; B. N. Nievas Soriano

Year: 2024

Venue: Nutrición clínica y dietética hospitalaria

DOI: https://doi.org/10.12873/443murillo

Paper Longevity and aging

Kaeberlein, Matt · 2013 · F1000Prime Reports · DOI

Full title: Longevity and aging

Authors: Kaeberlein, Matt

Year: 2013

Venue: F1000Prime Reports

DOI: https://doi.org/10.12703/p5-5

Paper Translational Geroscience: From invertebrate models to companion animal and human interventions.

Lee, Mitchell B; Kaeberlein, Matt · 2018 · Translational medicine of aging · DOI

Full title: Translational Geroscience: From invertebrate models to companion animal and human interventions.

Authors: Lee, Mitchell B; Kaeberlein, Matt

Year: 2018

Venue: Translational medicine of aging

DOI: https://doi.org/10.1016/j.tma.2018.08.002

Paper Perspectives of the potential implications of polyphenols in influencing the interrelationship between oxi-inflammatory stress, cellular senescence and immunosenescence during aging

Rohit Sharma; Y. Padwad · 2020 · Trends in Food Science & Technology · DOI

Full title: Perspectives of the potential implications of polyphenols in influencing the interrelationship between oxi-inflammatory stress, cellular senescence and immunosenescence during aging

Authors: Rohit Sharma; Y. Padwad

Year: 2020

Venue: Trends in Food Science & Technology

DOI: https://doi.org/10.1016/j.tifs.2020.02.004

Paper Exploring the potential of epigenetic clocks in aging research.

Hao, Yuduo; Han, Kaiyuan; Wang, Ting et al. · 2024 · Methods (San Diego, Calif.) · DOI

Full title: Exploring the potential of epigenetic clocks in aging research.

Authors: Hao, Yuduo; Han, Kaiyuan; Wang, Ting; Yu, Junwen; Ding, Hui; Dao, Fuying

Year: 2024

Venue: Methods (San Diego, Calif.)

DOI: https://doi.org/10.1016/j.ymeth.2024.09.001

Paper Strategy for identifying biomarkers of aging in long-lived species.

Ingram, D K; Nakamura, E; Smucny, D et al. · 2001 · Experimental gerontology · DOI

Full title: Strategy for identifying biomarkers of aging in long-lived species.

Authors: Ingram, D K; Nakamura, E; Smucny, D; Roth, G S; Lane, M A

Year: 2001

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/s0531-5565(01)00110-3

Paper Approaches to anti-aging intervention: the promises and the uncertainties.

Yu, B P · 1999 · Mechanisms of ageing and development · DOI

Full title: Approaches to anti-aging intervention: the promises and the uncertainties.

Authors: Yu, B P

Year: 1999

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/s0047-6374(99)00072-x

Paper Geroprotector efficiency depends on viability of control population: life span investigation in D. melanogaster.

D. M. Izmaylov; L. K. Obukhova · 1996 · Mechanisms of Ageing and Development · DOI

Full title: Geroprotector efficiency depends on viability of control population: life span investigation in D. melanogaster.

Authors: D. M. Izmaylov; L. K. Obukhova

Year: 1996

Venue: Mechanisms of Ageing and Development

DOI: https://doi.org/10.1016/s0047-6374(96)01776-9

Paper The multiomics blueprint of the individual with the most extreme lifespan.

Santos-Pujol, Eloy; Noguera-Castells, Aleix; Casado-Pelaez, Marta et al. · 2025 · Cell reports. Medicine · DOI

Full title: The multiomics blueprint of the individual with the most extreme lifespan.

Authors: Santos-Pujol, Eloy; Noguera-Castells, Aleix; Casado-Pelaez, Marta; García-Prieto, Carlos A; Vasallo, Claudia; Campillo-Marcos, Ignacio; Quero-Dotor, Carlos; Crespo-García, Eva; Bueno-Costa, Alberto; Setién, Fernando; Ferrer, Gerardo; Davalos, Veronica; Mereu, Elisabetta; Pluvinet, Raquel; Arribas, Carles; Torre, Carolina de la; Villavicencio, Francisco; Sumoy, Lauro; Granada, Isabel; Coles, Natalie S; Acha, Pamela; Solé, Francesc; Mallo, Mar; Mata, Caterina; Peregrina, Sara; Gabaldón, Toni; Llirós, Marc; Pujolassos, Meritxell; Carreras-Torres, Robert; Lluansí, Aleix; García-Gil, Librado Jesús; Aldeguer, Xavier; Samino, Sara; Torné, Pol; Ribalta, Josep; Guardiola, Montse; Amigó, Núria; Yanes, Oscar; Martínez, Paula; Sánchez-Vázquez, Raúl; Blasco, Maria A; Oviedo, Jose; Lemos, Bernardo; Rius-Bonet, Julia; Torrubiano, Marta; Massip-Salcedo, Marta; Khidir, Kamal A; Cao, Thong Huy; Quinn, Paulene A; Jones, Donald J L; Macip, Salvador; Brigos-Barril, Eva; Moldes, Mauricio; Barteri, Fabio; Muntané, Gerard; Laayouni, Hafid; Navarro, Arcadi; Esteller, Manel

Year: 2025

Venue: Cell reports. Medicine

DOI: https://doi.org/10.1016/j.xcrm.2025.102368

Paper Drosophila melanogaster as a model system in the study of pharmacological interventions in aging

Shinhae Lee; Kyung‐Jin Min · 2019 · Translational Medicine of Aging · DOI

Full title: Drosophila melanogaster as a model system in the study of pharmacological interventions in aging

Authors: Shinhae Lee; Kyung‐Jin Min

Year: 2019

Venue: Translational Medicine of Aging

DOI: https://doi.org/10.1016/j.tma.2019.09.004

Paper The relationship between aging and carcinogenesis: a critical appraisal.

Anisimov, Vladimir N · 2003 · Critical reviews in oncology/hematology · DOI

Full title: The relationship between aging and carcinogenesis: a critical appraisal.

Authors: Anisimov, Vladimir N

Year: 2003

Venue: Critical reviews in oncology/hematology

DOI: https://doi.org/10.1016/s1040-8428(02)00121-x

Paper Franklin Electric acquires Monarch Industries' Pump Division

· 2007 · Pump Industry Analyst · DOI

Full title: Franklin Electric acquires Monarch Industries' Pump Division

Year: 2007

Venue: Pump Industry Analyst

DOI: https://doi.org/10.1016/s1359-6128(07)70314-2

Paper Life span extension and cancer risk: myths and reality.

Anisimov, V N · 2001 · Experimental gerontology · DOI

Full title: Life span extension and cancer risk: myths and reality.

Authors: Anisimov, V N

Year: 2001

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/s0531-5565(01)00114-0

Paper Chemical Strategies for the Detection and Elimination of Senescent Cells.

García-Fleitas, Jessie; García-Fernández, Alba; Martí-Centelles, Vicente et al. · 2024 · Accounts of chemical research · DOI

Full title: Chemical Strategies for the Detection and Elimination of Senescent Cells.

Authors: García-Fleitas, Jessie; García-Fernández, Alba; Martí-Centelles, Vicente; Sancenón, Félix; Bernardos, Andrea; Martínez-Máñez, Ramón

Year: 2024

Venue: Accounts of chemical research

DOI: https://doi.org/10.1021/acs.accounts.3c00794

Paper Biotechnology, bioethics and anti-aging interventions.

Turner, Leigh · 2004 · Trends in biotechnology · DOI

Full title: Biotechnology, bioethics and anti-aging interventions.

Authors: Turner, Leigh

Year: 2004

Venue: Trends in biotechnology

DOI: https://doi.org/10.1016/j.tibtech.2004.03.008

Paper The costs and benefits of senotherapeutics for human health.

Raffaele, Marco; Vinciguerra, Manlio · 2022 · The lancet. Healthy longevity · DOI

Full title: The costs and benefits of senotherapeutics for human health.

Authors: Raffaele, Marco; Vinciguerra, Manlio

Year: 2022

Venue: The lancet. Healthy longevity

DOI: https://doi.org/10.1016/S2666-7568(21)00300-7

Paper Biological ageing with HIV infection: evaluating the geroscience hypothesis.

Montano, Monty; Oursler, Krisann K; Xu, Ke et al. · 2022 · The lancet. Healthy longevity · DOI

Full title: Biological ageing with HIV infection: evaluating the geroscience hypothesis.

Authors: Montano, Monty; Oursler, Krisann K; Xu, Ke; Sun, Yan V; Marconi, Vincent C

Year: 2022

Venue: The lancet. Healthy longevity

DOI: https://doi.org/10.1016/s2666-7568(21)00278-6

Paper Insulin and longevity: antidiabetic biguanides as geroprotectors.

Anisimov, Vladimir N; Semenchenko, Anna V; Yashin, Anatoli I · 2003 · Biogerontology · DOI

Full title: Insulin and longevity: antidiabetic biguanides as geroprotectors.

Authors: Anisimov, Vladimir N; Semenchenko, Anna V; Yashin, Anatoli I

Year: 2003

Venue: Biogerontology

DOI: https://doi.org/10.1023/a:1026299318315

Paper Ganoderma lucidum-Derived Nanovesicles Attenuate Multiorgan Senescence via Modulation of Oxidative Stress and Inflammation.

Qi, Fan; Zhang, Yu; Xie, Huijun et al. · 2026 · Molecular pharmaceutics · DOI

Full title: Ganoderma lucidum-Derived Nanovesicles Attenuate Multiorgan Senescence via Modulation of Oxidative Stress and Inflammation.

Authors: Qi, Fan; Zhang, Yu; Xie, Huijun; Guo, Xun; Zhang, Yuan

Year: 2026

Venue: Molecular pharmaceutics

DOI: https://doi.org/10.1021/acs.molpharmaceut.5c00862

Paper Reduced cytosolic protein synthesis suppresses mitochondrial degeneration.

Wang, Xiaowen; Zuo, Xiaoming; Kucejova, Blanka et al. · 2008 · Nature cell biology · DOI

Full title: Reduced cytosolic protein synthesis suppresses mitochondrial degeneration.

Authors: Wang, Xiaowen; Zuo, Xiaoming; Kucejova, Blanka; Chen, Xin Jie

Year: 2008

Venue: Nature cell biology

DOI: https://doi.org/10.1038/ncb1769

Paper A Targeting Senescence and Recycling Intracellular Nicotinamide Adenine Dinucleotide Strategy for Attenuation of Senescence-Associated Phenotypes.

Jian Liu; Mingjie Rong; Chen Liu et al. · 2025 · ACS Nano · DOI

Full title: A Targeting Senescence and Recycling Intracellular Nicotinamide Adenine Dinucleotide Strategy for Attenuation of Senescence-Associated Phenotypes.

Authors: Jian Liu; Mingjie Rong; Chen Liu; Lehui Lu

Year: 2025

Venue: ACS Nano

DOI: https://doi.org/10.1021/acsnano.5c05124

Paper Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.

Ewald, Collin Y; Landis, Jess N; Porter Abate, Jess et al. · 2015 · Nature · DOI

Full title: Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.

Authors: Ewald, Collin Y; Landis, Jess N; Porter Abate, Jess; Murphy, Coleen T; Blackwell, T Keith

Year: 2015

Venue: Nature

DOI: https://doi.org/10.1038/nature14021

Paper Age and life expectancy clocks based on machine learning analysis of mouse frailty

Schultz, Michael; Kane, Alice E.; Mitchell, Sarah J. et al. · 2020 · Nature Communications · DOI

Full title: Age and life expectancy clocks based on machine learning analysis of mouse frailty

Authors: Schultz, Michael; Kane, Alice E.; Mitchell, Sarah J.; MacArthur, Michael R.; Warner, Elisa; Vogel, David S.; Mitchell, James R.; Howlett, Susan E.; Bonkowski, Michael S.; Sinclair, David

Year: 2020

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-020-18446-0

Paper Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle

D. J. Ham; Anastasiya Börsch; Kathrin Chojnowska et al. · 2022 · Nature Communications · DOI

Full title: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle

Authors: D. J. Ham; Anastasiya Börsch; Kathrin Chojnowska; Shuo Lin; Aurel B. Leuchtmann; Alexander S. Ham; Marco Thürkauf; Julien Delezie; R. Furrer; Dominik Burri; M. Sinnreich; Christoph Handschin; L. Tintignac; M. Zavolan; Nitish Mittal; M. Rüegg

Year: 2022

Venue: Nature Communications

DOI: https://doi.org/10.1038/s41467-022-29714-6

Paper Nutrition senolytics - illusion or reality for cognitive ageing?

Chen, Xi; Brodaty, Henry; O'Leary, Fiona · 2022 · Current opinion in clinical nutrition and metabolic care · DOI

Full title: Nutrition senolytics - illusion or reality for cognitive ageing?

Authors: Chen, Xi; Brodaty, Henry; O'Leary, Fiona

Year: 2022

Venue: Current opinion in clinical nutrition and metabolic care

DOI: https://doi.org/10.1097/MCO.0000000000000796

Paper Targeting Cellular Senescence for Age-Related Diseases: Path to Clinical Translation.

Wyles, Saranya P; Tchkonia, Tamara; Kirkland, James L · 2022 · Plastic and reconstructive surgery · DOI

Full title: Targeting Cellular Senescence for Age-Related Diseases: Path to Clinical Translation.

Authors: Wyles, Saranya P; Tchkonia, Tamara; Kirkland, James L

Year: 2022

Venue: Plastic and reconstructive surgery

DOI: https://doi.org/10.1097/PRS.0000000000009669

Paper Preserving and rejuvenating old organs for transplantation: novel treatments including the potential of senolytics.

Matsunaga, Tomohisa; Roesel, Maximilian J; Schroeter, Andreas et al. · 2022 · Current opinion in organ transplantation · DOI

Full title: Preserving and rejuvenating old organs for transplantation: novel treatments including the potential of senolytics.

Authors: Matsunaga, Tomohisa; Roesel, Maximilian J; Schroeter, Andreas; Xiao, Yao; Zhou, Hao; Tullius, Stefan G

Year: 2022

Venue: Current opinion in organ transplantation

DOI: https://doi.org/10.1097/MOT.0000000000001019

Paper Longevity interventions in Titan mice attenuate frailty and senescence accumulation

Benedikt Gille; Annika Müller-Eigner; Shari Gottschalk et al. · 2023 · bioRxiv · DOI

Full title: Longevity interventions in Titan mice attenuate frailty and senescence accumulation

Authors: Benedikt Gille; Annika Müller-Eigner; Shari Gottschalk; Erika Wytrwat; Martina Langhammer; S. Peleg

Year: 2023

Venue: bioRxiv

DOI: https://doi.org/10.1101/2023.09.08.556694

Paper Increased alcohol dehydrogenase 1 activity promotes longevity.

Ghaddar, Abbas; Mony, Vinod K; Mishra, Swarup et al. · 2023 · Current biology : CB · DOI

Full title: Increased alcohol dehydrogenase 1 activity promotes longevity.

Authors: Ghaddar, Abbas; Mony, Vinod K; Mishra, Swarup; Berhanu, Samuel; Johnson, James C; Enriquez-Hesles, Elisa; Harrison, Emma; Patel, Aaroh; Horak, Mary Kate; Smith, Jeffrey S; O'Rourke, Eyleen J

Year: 2023

Venue: Current biology : CB

DOI: https://doi.org/10.1016/j.cub.2023.01.059

Paper Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential

Balasubramanian, Priya; Howell, Porsha R.; Anderson, Rozalyn M. · 2017 · EBioMedicine · DOI

Full title: Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential

Authors: Balasubramanian, Priya; Howell, Porsha R.; Anderson, Rozalyn M.

Year: 2017

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2017.06.015

Paper Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease.

Bian, Xiaohui; Snow, Zachary K; Zinn, Caroline J et al. · 2026 · EBioMedicine · DOI

Full title: Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease.

Authors: Bian, Xiaohui; Snow, Zachary K; Zinn, Caroline J; Bratulin, Anastasia L; Elhusseiny, Khaled M; Tchkonia, Tamar; Kirkland, James L; Zhu, Yi; Khosla, Sundeep; Kim, Seo Rin; Lerman, Lilach O; Hickson, LaTonya J

Year: 2026

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2026.106124

Paper Fisetin is a senotherapeutic that extends health and lifespan

Matthew J. Yousefzadeh; Yi Zhu; S. McGowan et al. · 2018 · EBioMedicine · DOI

Full title: Fisetin is a senotherapeutic that extends health and lifespan

Authors: Matthew J. Yousefzadeh; Yi Zhu; S. McGowan; Luise A Angelini; Heike Fuhrmann-Stroissnigg; Ming Xu; Y. Ling; Kendra I. Melos; T. Pirtskhalava; C. Inman; Collin A McGuckian; Erin A. Wade; J. I. Kato; D. Grassi; M. Wentworth; C. Burd; E. Arriaga; Warren Ladiges; T. Tchkonia; J. Kirkland; P. Robbins; L. Niedernhofer

Year: 2018

Venue: EBioMedicine

DOI: https://doi.org/10.1016/j.ebiom.2018.09.015

Paper Aging in chronic lung disease: Will anti-aging therapy be the key to the cure?

Wang, Weijie; Zhou, Kai; Wang, Leyuan et al. · 2024 · European journal of pharmacology · DOI

Full title: Aging in chronic lung disease: Will anti-aging therapy be the key to the cure?

Authors: Wang, Weijie; Zhou, Kai; Wang, Leyuan; Qin, Qiuyan; Liu, Huijun; Qin, Ling; Yang, Ming; Yuan, Lin; Liu, Chi

Year: 2024

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2024.176846

Paper Stressors and antistressors: how do they influence life span in HER-2/neu transgenic mice?

Semenchenko, Ganna V; Anisimov, Vladimir N; Yashin, Anatoli I · 2004 · Experimental gerontology · DOI

Full title: Stressors and antistressors: how do they influence life span in HER-2/neu transgenic mice?

Authors: Semenchenko, Ganna V; Anisimov, Vladimir N; Yashin, Anatoli I

Year: 2004

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2004.08.007

Paper Investigating the bidirectional interactions between senotherapeutic agents and human gut microbiota.

Sangfuang, Nannapat; Xie, Yuan; McCoubrey, Laura E et al. · 2025 · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · DOI

Full title: Investigating the bidirectional interactions between senotherapeutic agents and human gut microbiota.

Authors: Sangfuang, Nannapat; Xie, Yuan; McCoubrey, Laura E; Taub, Marissa; Favaron, Alessia; Mai, Yang; Gaisford, Simon; Basit, Abdul W

Year: 2025

Venue: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

DOI: https://doi.org/10.1016/j.ejps.2025.107098

Paper STOP accelerating lung aging for the treatment of COPD.

Ito, Kazuhiro; Mercado, Nicolas · 2014 · Experimental gerontology · DOI

Full title: STOP accelerating lung aging for the treatment of COPD.

Authors: Ito, Kazuhiro; Mercado, Nicolas

Year: 2014

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2014.03.014

Paper Protein kinases as targets for interventive biogerontology: Overview and perspectives

Lai, Wing‐Fu · 2012 · Experimental Gerontology · DOI

Full title: Protein kinases as targets for interventive biogerontology: Overview and perspectives

Authors: Lai, Wing‐Fu

Year: 2012

Venue: Experimental Gerontology

DOI: https://doi.org/10.1016/j.exger.2012.01.002

Paper Healthy aging: A bibliometric analysis of the literature.

Gu, Yao-Hua; Bai, Jin-Bing; Chen, Xiao-Li et al. · 2019 · Experimental gerontology · DOI

Full title: Healthy aging: A bibliometric analysis of the literature.

Authors: Gu, Yao-Hua; Bai, Jin-Bing; Chen, Xiao-Li; Wu, Wen-Wen; Liu, Xiang-Xiang; Tan, Xiao-Dong

Year: 2019

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2018.11.014

Paper Nutritional limitation in early postnatal life and its effect on aging and longevity in rodents.

Davis, Kallie; Chamseddine, Douja; Harper, James M · 2016 · Experimental gerontology · DOI

Full title: Nutritional limitation in early postnatal life and its effect on aging and longevity in rodents.

Authors: Davis, Kallie; Chamseddine, Douja; Harper, James M

Year: 2016

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2016.05.001

Paper Differential effects of calorie restriction and rapamycin on age-related molecular and functional changes in skeletal muscle.

Orenduff, Melissa C; Coleman, Michael F; Glenny, Elaine M et al. · 2022 · Experimental gerontology · DOI

Full title: Differential effects of calorie restriction and rapamycin on age-related molecular and functional changes in skeletal muscle.

Authors: Orenduff, Melissa C; Coleman, Michael F; Glenny, Elaine M; Huffman, Kim M; Rezeli, Erika T; Bareja, Akshay; Pieper, Carl F; Kraus, Virginia B; Hursting, Stephen D

Year: 2022

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2022.111841

Paper Senescent cell-derived extracellular vesicles as potential mediators of innate immunosenescence and inflammaging.

Hanley, Shaun; Chen, Yung-Yi; Hazeldine, Jon et al. · 2024 · Experimental gerontology · DOI

Full title: Senescent cell-derived extracellular vesicles as potential mediators of innate immunosenescence and inflammaging.

Authors: Hanley, Shaun; Chen, Yung-Yi; Hazeldine, Jon; Lord, Janet M

Year: 2024

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2024.112365

Paper Metformin turns 62 in pharmacotherapy: Emergence of non-glycaemic effects and potential novel therapeutic applications.

Mbara, Kingsley C; Mofo Mato, Pascale E; Driver, Christine et al. · 2021 · European journal of pharmacology · DOI

Full title: Metformin turns 62 in pharmacotherapy: Emergence of non-glycaemic effects and potential novel therapeutic applications.

Authors: Mbara, Kingsley C; Mofo Mato, Pascale E; Driver, Christine; Nzuza, Sanelisiwe; Mkhombo, Ntokozo T; Gcwensa, Senamile Kp; Mcobothi, Esethu N; Owira, Peter Mo

Year: 2021

Venue: European journal of pharmacology

DOI: https://doi.org/10.1016/j.ejphar.2021.173934

Paper Senolytics and the compression of late-life mortality.

Kowald, Axel; Kirkwood, Thomas B L · 2021 · Experimental gerontology · DOI

Full title: Senolytics and the compression of late-life mortality.

Authors: Kowald, Axel; Kirkwood, Thomas B L

Year: 2021

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2021.111588

Paper The effect of short-term methionine restriction on glutathione synthetic capacity and antioxidant responses at the whole tissue and mitochondrial level in the rat liver.

Tamanna, Nahid; Kroeker, Kathryn; Braun, Kristen et al. · 2019 · Experimental gerontology · DOI

Full title: The effect of short-term methionine restriction on glutathione synthetic capacity and antioxidant responses at the whole tissue and mitochondrial level in the rat liver.

Authors: Tamanna, Nahid; Kroeker, Kathryn; Braun, Kristen; Banh, Sheena; Treberg, Jason R

Year: 2019

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2019.110712

Paper Fecal and urinary NMR-based metabolomics unveil an aging signature in mice.

Calvani, Riccardo; Brasili, Elisa; Praticò, Giulia et al. · 2014 · Experimental gerontology · DOI

Full title: Fecal and urinary NMR-based metabolomics unveil an aging signature in mice.

Authors: Calvani, Riccardo; Brasili, Elisa; Praticò, Giulia; Capuani, Giorgio; Tomassini, Alberta; Marini, Federico; Sciubba, Fabio; Finamore, Alberto; Roselli, Marianna; Marzetti, Emanuele; Miccheli, Alfredo

Year: 2014

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2013.10.010

Paper Metabolic regulation of aged hematopoietic stem cells: key players and mechanisms

Karimnia, Nazanin; Harris, James; Heazlewood, Shen Y. et al. · 2023 · Experimental Hematology · DOI

Full title: Metabolic regulation of aged hematopoietic stem cells: key players and mechanisms

Authors: Karimnia, Nazanin; Harris, James; Heazlewood, Shen Y.; Cao, Benjamin; Nilsson, Susan K.

Year: 2023

Venue: Experimental Hematology

DOI: https://doi.org/10.1016/j.exphem.2023.09.006

Paper Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content.

Chubanava, Sabina; Treebak, Jonas T · 2023 · Experimental gerontology · DOI

Full title: Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content.

Authors: Chubanava, Sabina; Treebak, Jonas T

Year: 2023

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2023.112109

Paper Mild calorie restriction, but not 17α-estradiol, extends ovarian reserve and fertility in female mice.

Isola, José V V; Zanini, Bianka M; Hense, Jessica D et al. · 2022 · Experimental gerontology · DOI

Full title: Mild calorie restriction, but not 17α-estradiol, extends ovarian reserve and fertility in female mice.

Authors: Isola, José V V; Zanini, Bianka M; Hense, Jessica D; Alvarado-Rincón, Joao A; Garcia, Driele N; Pereira, Giulia C; Vieira, Arnaldo D; Oliveira, Thais L; Collares, Tiago; Gasperin, Bernardo G; Stout, Michael B; Schneider, Augusto

Year: 2022

Venue: Experimental gerontology

DOI: https://doi.org/10.1016/j.exger.2021.111669

Paper Repurposing approved drugs as geroprotectors: Experimental versus epidemiological evidence

M. Ristow · 2021 · DOI

Full title: Repurposing approved drugs as geroprotectors: Experimental versus epidemiological evidence

Authors: M. Ristow

Year: 2021

DOI: https://doi.org/10.1016/j.freeradbiomed.2020.12.274

Paper Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds.

Cano, Mercedes; Guerrero-Castilla, Angelica; Nabavi, Seyed Mohammad et al. · 2019 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · DOI

Full title: Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds.

Authors: Cano, Mercedes; Guerrero-Castilla, Angelica; Nabavi, Seyed Mohammad; Ayala, Antonio; Argüelles, Sandro

Year: 2019

Venue: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

DOI: https://doi.org/10.1016/j.fct.2019.05.052

Paper P21/P16 Senescence Heterogeneity In Diabetic Bone

Yan, Jiayu; Shi, Jiaying; Zhao, Ruowen et al. · 2025 · International Dental Journal · DOI

Full title: P21/P16 Senescence Heterogeneity In Diabetic Bone

Authors: Yan, Jiayu; Shi, Jiaying; Zhao, Ruowen; Wu, Junhua; Chen, Siyi

Year: 2025

Venue: International Dental Journal

DOI: https://doi.org/10.1016/j.identj.2025.105294

Paper Oxidative phosphorylation and fatty acid oxidation in slow-aging mice.

Elmansi, Ahmed M; Miller, Richard A · 2024 · Free radical biology & medicine · DOI

Full title: Oxidative phosphorylation and fatty acid oxidation in slow-aging mice.

Authors: Elmansi, Ahmed M; Miller, Richard A

Year: 2024

Venue: Free radical biology & medicine

DOI: https://doi.org/10.1016/j.freeradbiomed.2024.08.018

Paper Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

Amirhossein Nayeri Rad; Golnaz Shams; R. Avelar et al. · 2022 · Informatics in Medicine Unlocked · DOI

Full title: Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

Authors: Amirhossein Nayeri Rad; Golnaz Shams; R. Avelar; Mohammad Hossein Morowvat; Y. Ghasemi

Year: 2022

Venue: Informatics in Medicine Unlocked

DOI: https://doi.org/10.1016/j.imu.2022.100920

Paper Longevity interventions temporally scale healthspan in Caenorhabditis elegans.

Statzer, Cyril; Reichert, Peter; Dual, Jürg et al. · 2022 · iScience · DOI

Full title: Longevity interventions temporally scale healthspan in Caenorhabditis elegans.

Authors: Statzer, Cyril; Reichert, Peter; Dual, Jürg; Ewald, Collin Y

Year: 2022

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2022.103983

Paper Rejuvenation of young blood on aging organs: Effects, circulating factors, and mechanisms.

Liu, Meng-Nan; Lan, Qi; Wu, Hao et al. · 2024 · Heliyon · DOI

Full title: Rejuvenation of young blood on aging organs: Effects, circulating factors, and mechanisms.

Authors: Liu, Meng-Nan; Lan, Qi; Wu, Hao; Qiu, Cai-Wei

Year: 2024

Venue: Heliyon

DOI: https://doi.org/10.1016/j.heliyon.2024.e32652

Paper Tolerance to NADH/NAD+ imbalance anticipates aging and anti-aging interventions.

Alonso-Lavin, Alvar J; Bajić, Djordje; Poyatos, Juan F · 2021 · iScience · DOI

Full title: Tolerance to NADH/NAD+ imbalance anticipates aging and anti-aging interventions.

Authors: Alonso-Lavin, Alvar J; Bajić, Djordje; Poyatos, Juan F

Year: 2021

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2021.102697

Paper HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.

Tammaro, Alessandra; Daniels, Eileen G; Hu, Iman M et al. · 2024 · iScience · DOI

Full title: HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.

Authors: Tammaro, Alessandra; Daniels, Eileen G; Hu, Iman M; 't Hart, Kelly C; Reid, Kim; Juni, Rio P; Butter, Loes M; Vasam, Goutham; Kamble, Rashmi; Jongejan, Aldo; Aviv, Richard I; Roelofs, Joris J T H; Aronica, Eleonora; Boon, Reinier A; Menzies, Keir J; Houtkooper, Riekelt H; Janssens, Georges E

Year: 2024

Venue: iScience

DOI: https://doi.org/10.1016/j.isci.2023.108681

Paper Extracellular vesicle as therapeutic agents in anti-aging: Mechanistic insights and future potential.

Yoon, Hyejoo; Jo, Junyeong; Hyun, Hyesun et al. · 2025 · Journal of controlled release : official journal of the Controlled Release Society · DOI

Full title: Extracellular vesicle as therapeutic agents in anti-aging: Mechanistic insights and future potential.

Authors: Yoon, Hyejoo; Jo, Junyeong; Hyun, Hyesun; Lee, Gyuwon; Ma, Seoyoung; Sohn, Jungho; Sung, Dong Kyung; Han, Chae Young; Kim, Minkyung; Hwang, Duhyeong; Lee, Hyunji; Shin, Yuseon; Oh, Kyung Taek; Lim, Chaemin

Year: 2025

Venue: Journal of controlled release : official journal of the Controlled Release Society

DOI: https://doi.org/10.1016/j.jconrel.2025.113796

Paper Links Between Autophagy and Healthy Aging.

Ebata, Hiroshi; Hansen, Malene · 2026 · Journal of molecular biology · DOI

Full title: Links Between Autophagy and Healthy Aging.

Authors: Ebata, Hiroshi; Hansen, Malene

Year: 2026

Venue: Journal of molecular biology

DOI: https://doi.org/10.1016/j.jmb.2026.169656

Paper Senotherapy, cancer, and aging.

Balducci, Lodovico; Falandry, Claire; Silvio Monfardini · 2024 · Journal of geriatric oncology · DOI

Full title: Senotherapy, cancer, and aging.

Authors: Balducci, Lodovico; Falandry, Claire; Silvio Monfardini

Year: 2024

Venue: Journal of geriatric oncology

DOI: https://doi.org/10.1016/j.jgo.2023.101671

Paper Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues.

Garcia, Ana Maria; Busuttil, Rita A; Calder, R Brent et al. · 2008 · Mechanisms of ageing and development · DOI

Full title: Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues.

Authors: Garcia, Ana Maria; Busuttil, Rita A; Calder, R Brent; Dollé, Martijn E T; Diaz, Vivian; McMahan, C Alex; Bartke, Andrzej; Nelson, James; Reddick, Robert; Vijg, Jan

Year: 2008

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2008.04.013

Paper Nutrition and aging.

W. Cheng; V. Bohr; R. Cabo · 2010 · Mechanisms of Ageing and Development · DOI

Full title: Nutrition and aging.

Authors: W. Cheng; V. Bohr; R. Cabo

Year: 2010

Venue: Mechanisms of Ageing and Development

DOI: https://doi.org/10.1016/j.mad.2010.03.011

Paper Frailty index as a biomarker of lifespan and healthspan: Focus on pharmacological interventions.

Palliyaguru, Dushani L; Moats, Jacqueline M; Di Germanio, Clara et al. · 2019 · Mechanisms of ageing and development · DOI

Full title: Frailty index as a biomarker of lifespan and healthspan: Focus on pharmacological interventions.

Authors: Palliyaguru, Dushani L; Moats, Jacqueline M; Di Germanio, Clara; Bernier, Michel; de Cabo, Rafael

Year: 2019

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2019.03.005

Paper Is metformin a geroprotector? A peek into the current clinical and experimental data

Agnieszka Zajda; K. Huttunen; J. Sikora et al. · 2020 · Mechanisms of Ageing and Development · DOI

Full title: Is metformin a geroprotector? A peek into the current clinical and experimental data

Authors: Agnieszka Zajda; K. Huttunen; J. Sikora; Maria Podsiedlik; M. Markowicz-Piasecka

Year: 2020

Venue: Mechanisms of Ageing and Development

DOI: https://doi.org/10.1016/j.mad.2020.111350

Paper Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Cohen, Alan A.; Kennedy, Brian K.; Anglas, Ulrich et al. · 2020 · Mechanisms of Ageing and Development · DOI

Full title: Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Authors: Cohen, Alan A.; Kennedy, Brian K.; Anglas, Ulrich; Bronikowski, Anne M.; Deelen, Joris; Dufour, Frédérik; Ferbeyre, Gerardo; Ferrucci, Luigi; Franceschi, Claudio; Frasca, Daniela; Friguet, Bertrand; Gaudreau, Pierrette; Gladyshev, Vadim N.; Gonos, Efstathios S.; Gorbunova, Vera; Gut, Philipp; Ivanchenko, Mikhail; Legault, Véronique; Lemaître, Jean‐François; Liontis, Thomas; Liu, Guang‐Hui; Liu, Mingxin; Maier, Andrea B.; Nóbrega, Otávio de Tolêdo; Rikkert, Marcel G. M. Olde; Pawelec, Graham; Rheault, Sylvie; Senior, Alistair M.; Simm, Andreas; Soo, Sonja K.; Traa, Annika; Ukraintseva, Svetlana; Vanhaelen, Quentin; Raamsdonk, Jeremy M. Van; Witkowski, Jacek M.; Yashin, Anatoliy I.; Ziman, Robert; Fülöp, Tamàs

Year: 2020

Venue: Mechanisms of Ageing and Development

DOI: https://doi.org/10.1016/j.mad.2020.111316

Paper Interventions for age-related diseases: Shifting the paradigm.

Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra et al. · 2016 · Mechanisms of ageing and development · DOI

Full title: Interventions for age-related diseases: Shifting the paradigm.

Authors: Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra; Lopez-Contreras, Andres; Henriques, Catarina M; Selman, Colin; Ferreiro, Elisabete; Gonos, Efstathios S; Trejo, José Luis; Misra, Juhi; Rasmussen, Lene Juel; Xapelli, Sara; Ellam, Timothy; Bellantuono, Ilaria

Year: 2016

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2016.09.009

Paper Geroprotectors: A role in the treatment of frailty.

Trendelenburg, A U; Scheuren, A C; Potter, P et al. · 2019 · Mechanisms of ageing and development · DOI

Full title: Geroprotectors: A role in the treatment of frailty.

Authors: Trendelenburg, A U; Scheuren, A C; Potter, P; Müller, R; Bellantuono, I

Year: 2019

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2019.03.002

Paper Anti-aging interventions in geriatric mice: insights into the timing of treatment, benefits, and limitations.

Malavolta, Marco · 2025 · GeroScience · DOI

Full title: Anti-aging interventions in geriatric mice: insights into the timing of treatment, benefits, and limitations.

Authors: Malavolta, Marco

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01309-7

Paper Titan mice as a model to test interventions that attenuate frailty and increase longevity.

Gille, Benedikt; Müller-Eigner, Annika; Gottschalk, Shari et al. · 2024 · GeroScience · DOI

Full title: Titan mice as a model to test interventions that attenuate frailty and increase longevity.

Authors: Gille, Benedikt; Müller-Eigner, Annika; Gottschalk, Shari; Wytrwat, Erika; Langhammer, Martina; Peleg, Shahaf

Year: 2024

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-023-01045-4

Paper Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions.

Elmansi, Ahmed M; Kassem, Abraham; Castilla, Rafael M et al. · 2025 · GeroScience · DOI

Full title: Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions.

Authors: Elmansi, Ahmed M; Kassem, Abraham; Castilla, Rafael M; Miller, Richard A

Year: 2025

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-024-01466-9

Paper Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements.

Van Damme, Menno; Stegen, Sanne; Steenwinckel, Bram et al. · 2026 · GeroScience · DOI

Full title: Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements.

Authors: Van Damme, Menno; Stegen, Sanne; Steenwinckel, Bram; Schroé, Helene; Reyes Del Paso, Gustavo A; Pulopulos, Matias M; De Raedt, Rudi; Vanderhasselt, Marie-Anne; Derave, Wim; Ongenae, Femke; Boone, Jan; Van Criekinge, Wim; Rietzschel, Ernst R; De Meyer, Tim

Year: 2026

Venue: GeroScience

DOI: https://doi.org/10.1007/s11357-025-02076-9

Paper New Directions in Research on Aging.

Bartke, Andrzej · 2022 · Stem cell reviews and reports · DOI

Full title: New Directions in Research on Aging.

Authors: Bartke, Andrzej

Year: 2022

Venue: Stem cell reviews and reports

DOI: https://doi.org/10.1007/s12015-021-10305-9

Paper The Ethics of Anti-aging Clinical Trials.

Crutchfield, Parker · 2018 · Science and engineering ethics · DOI

Full title: The Ethics of Anti-aging Clinical Trials.

Authors: Crutchfield, Parker

Year: 2018

Venue: Science and engineering ethics

DOI: https://doi.org/10.1007/s11948-017-9917-z

Paper NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health

Alegre, Gabriela Fabiana Soares; Pastore, Gláucia María · 2023 · Current Nutrition Reports · DOI

Full title: NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health

Authors: Alegre, Gabriela Fabiana Soares; Pastore, Gláucia María

Year: 2023

Venue: Current Nutrition Reports

DOI: https://doi.org/10.1007/s13668-023-00475-y

Paper Journal of Nutrition, Health & Aging: Summary of Recent Work and Future Directions

P. de Souto Barreto; J. G. Ruiz; R.A. Merchant · 2022 · The Journal of Nutrition, Health & Aging · DOI

Full title: Journal of Nutrition, Health & Aging: Summary of Recent Work and Future Directions

Authors: P. de Souto Barreto; J. G. Ruiz; R.A. Merchant

Year: 2022

Venue: The Journal of Nutrition, Health & Aging

DOI: https://doi.org/10.1007/s12603-022-1725-8

Paper Dietary restriction in the epigenomic regulation of cardiovascular diseases

Shinmura, Ken · 2019 · Elsevier eBooks · DOI

Full title: Dietary restriction in the epigenomic regulation of cardiovascular diseases

Authors: Shinmura, Ken

Year: 2019

Venue: Elsevier eBooks

DOI: https://doi.org/10.1016/b978-0-12-816843-1.00017-5

Paper Mitochondrial biogenesis and mitophagy

Sijie Tan; B. Kennedy; E. Wong · 2021 · Mitochondrial Physiology and Vegetal Molecules · DOI

Full title: Mitochondrial biogenesis and mitophagy

Authors: Sijie Tan; B. Kennedy; E. Wong

Year: 2021

Venue: Mitochondrial Physiology and Vegetal Molecules

DOI: https://doi.org/10.1016/b978-0-12-821562-3.00037-x

Paper Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction.

Nehlin, Jan O · 2023 · Advances in protein chemistry and structural biology · DOI

Full title: Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction.

Authors: Nehlin, Jan O

Year: 2023

Venue: Advances in protein chemistry and structural biology

DOI: https://doi.org/10.1016/bs.apcsb.2023.02.020

Paper Protein kinase modulation for anti-aging intervention

Muñoz, Mario; Argüelles, Sandro; Ayala, Antonio et al. · 2023 · Elsevier eBooks · DOI

Full title: Protein kinase modulation for anti-aging intervention

Authors: Muñoz, Mario; Argüelles, Sandro; Ayala, Antonio; Marotta, Francesco

Year: 2023

Venue: Elsevier eBooks

DOI: https://doi.org/10.1016/b978-0-12-823679-6.00011-4

Paper Understanding the relationship between oxidative stress and cognition in the elderly

Naomi Perry; Laura Martin; F. Rosenfeldt et al. · 2021 · Elsevier eBooks · DOI

Full title: Understanding the relationship between oxidative stress and cognition in the elderly

Authors: Naomi Perry; Laura Martin; F. Rosenfeldt; Ruchong Ou; R. Rowsell; C. Stough

Year: 2021

Venue: Elsevier eBooks

DOI: https://doi.org/10.1016/b978-0-12-820593-8.00006-9

Paper Senotherapeutics: Milestones, innovations, and future prospects.

Atasever, Erdem; Atayik, Mehmet Can; Çakatay, Ufuk · 2025 · Advances in pharmacology (San Diego, Calif.) · DOI

Full title: Senotherapeutics: Milestones, innovations, and future prospects.

Authors: Atasever, Erdem; Atayik, Mehmet Can; Çakatay, Ufuk

Year: 2025

Venue: Advances in pharmacology (San Diego, Calif.)

DOI: https://doi.org/10.1016/bs.apha.2025.01.021

Paper Pharmacological frontiers in senescence: Transforming senescence with drug repurposing.

Shahzadi, Andleeb; Ozyazgan, Sibel; Çakatay, Ufuk · 2025 · Advances in pharmacology (San Diego, Calif.) · DOI

Full title: Pharmacological frontiers in senescence: Transforming senescence with drug repurposing.

Authors: Shahzadi, Andleeb; Ozyazgan, Sibel; Çakatay, Ufuk

Year: 2025

Venue: Advances in pharmacology (San Diego, Calif.)

DOI: https://doi.org/10.1016/bs.apha.2025.02.010

Paper A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.

Escriche-Navarro, Blanca; Garrido, Eva; Sancenón, Félix et al. · 2024 · Acta biomaterialia · DOI

Full title: A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.

Authors: Escriche-Navarro, Blanca; Garrido, Eva; Sancenón, Félix; García-Fernández, Alba; Martínez-Máñez, Ramón

Year: 2024

Venue: Acta biomaterialia

DOI: https://doi.org/10.1016/j.actbio.2024.01.002

Paper Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence.

Joon-Tae Park; Young-Sam Lee; K. Cho et al. · 2018 · Ageing Research Reviews · DOI

Full title: Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence.

Authors: Joon-Tae Park; Young-Sam Lee; K. Cho; S. Park

Year: 2018

Venue: Ageing Research Reviews

DOI: https://doi.org/10.1016/j.arr.2018.08.003

Paper The road ahead for health and lifespan interventions.

Gonzalez-Freire, Marta; Diaz-Ruiz, Alberto; Hauser, David et al. · 2020 · Ageing research reviews · DOI

Full title: The road ahead for health and lifespan interventions.

Authors: Gonzalez-Freire, Marta; Diaz-Ruiz, Alberto; Hauser, David; Martinez-Romero, Jorge; Ferrucci, Luigi; Bernier, Michel; de Cabo, Rafael

Year: 2020

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2020.101037

Paper Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity.

McIntyre, Rebecca L; Liu, Yasmine J; Hu, Man et al. · 2022 · Ageing research reviews · DOI

Full title: Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity.

Authors: McIntyre, Rebecca L; Liu, Yasmine J; Hu, Man; Morris, Brian J; Willcox, Bradley J; Donlon, Timothy A; Houtkooper, Riekelt H; Janssens, Georges E

Year: 2022

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2022.101621

Paper Compound combinations targeting longevity: Challenges and perspectives.

Rybina, Olga Y; Symonenko, Alexander V; Pasyukova, Elena G · 2023 · Ageing research reviews · DOI

Full title: Compound combinations targeting longevity: Challenges and perspectives.

Authors: Rybina, Olga Y; Symonenko, Alexander V; Pasyukova, Elena G

Year: 2023

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2023.101851

Paper Metallothionein and the biology of aging.

Swindell, William R · 2011 · Ageing research reviews · DOI

Full title: Metallothionein and the biology of aging.

Authors: Swindell, William R

Year: 2011

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2010.09.007

Paper Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend.

Arora, Sakshi; Mittal, Aayushi; Duari, Subhadeep et al. · 2025 · Nature aging · DOI

Full title: Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend.

Authors: Arora, Sakshi; Mittal, Aayushi; Duari, Subhadeep; Chauhan, Sonam; Dixit, Nilesh Kumar; Mohanty, Sanjay Kumar; Sharma, Arushi; Solanki, Saveena; Sharma, Anmol Kumar; Gautam, Vishakha; Gahlot, Pushpendra Singh; Satija, Shiva; Nanshi, Jeet; Kapoor, Nikita; Cb, Lavanya; Sengupta, Debarka; Mehrotra, Parul; Ghosh, Tarini Shankar; Ahuja, Gaurav

Year: 2025

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-024-00763-4

Paper CHAPTER 4:Testing of Geroprotectors in Experiments on Cell Cultures: Pros and Cons

A. Khokhlov; G. Morgunova · 2017 · RSC drug discovery/RSC drug discovery series · DOI

Full title: CHAPTER 4:Testing of Geroprotectors in Experiments on Cell Cultures: Pros and Cons

Authors: A. Khokhlov; G. Morgunova

Year: 2017

Venue: RSC drug discovery/RSC drug discovery series

DOI: https://doi.org/10.1039/9781782626602-00051

Paper A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing.

Dhokia, Vinesh; Albati, Amal; Smith, Hannah et al. · 2024 · Biochemical Society transactions · DOI

Full title: A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing.

Authors: Dhokia, Vinesh; Albati, Amal; Smith, Hannah; Thomas, Gethin; Macip, Salvador

Year: 2024

Venue: Biochemical Society transactions

DOI: https://doi.org/10.1042/BST20231066

Paper Fasting mimicking diet extends lifespan and improves intestinal and cognitive health.

Qingyi Wang; Jilei Xu; Man Luo et al. · 2024 · Food & Function · DOI

Full title: Fasting mimicking diet extends lifespan and improves intestinal and cognitive health.

Authors: Qingyi Wang; Jilei Xu; Man Luo; Yao Jiang; Yanrou Gu; Qiwen Wang; Jiamin He; Yong Sun; Yifeng Lin; Lijun Feng; Shujie Chen; Tongyao Hou

Year: 2024

Venue: Food & Function

DOI: https://doi.org/10.1039/d4fo00483c

Paper Biomarkers for aging in Caenorhabditis elegans high throughput screening.

Yarmey, Victoria R; San-Miguel, Adriana · 2024 · Biochemical Society transactions · DOI

Full title: Biomarkers for aging in Caenorhabditis elegans high throughput screening.

Authors: Yarmey, Victoria R; San-Miguel, Adriana

Year: 2024

Venue: Biochemical Society transactions

DOI: https://doi.org/10.1042/BST20231303

Paper Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies

Selesniemi, Kaisa; Lee, Ho‐Joon; Muhlhauser, Ailene et al. · 2011 · Proceedings of the National Academy of Sciences · DOI

Full title: Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies

Authors: Selesniemi, Kaisa; Lee, Ho‐Joon; Muhlhauser, Ailene; Tilly, Jonathan L.

Year: 2011

Venue: Proceedings of the National Academy of Sciences

DOI: https://doi.org/10.1073/pnas.1018793108

Paper Hsp90 inhibitors as senolytic drugs to extend healthy aging

Heike Fuhrmann-Stroissnigg; L. Niedernhofer; P. Robbins · 2018 · Cell Cycle · DOI

Full title: Hsp90 inhibitors as senolytic drugs to extend healthy aging

Authors: Heike Fuhrmann-Stroissnigg; L. Niedernhofer; P. Robbins

Year: 2018

Venue: Cell Cycle

DOI: https://doi.org/10.1080/15384101.2018.1475828

Paper Candidate molecular targets uncovered in mouse lifespan extension studies.

Vedunova, Maria; Borysova, Olga; Kozlov, Grigory et al. · 2024 · Expert opinion on therapeutic targets · DOI

Full title: Candidate molecular targets uncovered in mouse lifespan extension studies.

Authors: Vedunova, Maria; Borysova, Olga; Kozlov, Grigory; Zharova, Anna-Maria; Morgunov, Ivan; Moskalev, Alexey

Year: 2024

Venue: Expert opinion on therapeutic targets

DOI: https://doi.org/10.1080/14728222.2024.2346597

Paper Autophagy promotes visceral aging in wild-type C. elegans.

Benedetto, Alexandre; Gems, David · 2019 · Autophagy · DOI

Full title: Autophagy promotes visceral aging in wild-type C. elegans.

Authors: Benedetto, Alexandre; Gems, David

Year: 2019

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2019.1569919

Paper The ongoing challenge of slowing ageing through drug discovery.

Le Couteur, David G; Simpson, Stephen J; Cogger, Victoria C et al. · 2025 · Expert opinion on drug discovery · DOI

Full title: The ongoing challenge of slowing ageing through drug discovery.

Authors: Le Couteur, David G; Simpson, Stephen J; Cogger, Victoria C; Thillainadesan, Janani; Anderson, Rozalyn; de Cabo, Rafael

Year: 2025

Venue: Expert opinion on drug discovery

DOI: https://doi.org/10.1080/17460441.2025.2482063

Paper Intermittent time-restricted feeding promotes longevity through circadian autophagy.

Yin, Zhangyuan; Klionsky, Daniel J · 2022 · Autophagy · DOI

Full title: Intermittent time-restricted feeding promotes longevity through circadian autophagy.

Authors: Yin, Zhangyuan; Klionsky, Daniel J

Year: 2022

Venue: Autophagy

DOI: https://doi.org/10.1080/15548627.2022.2039524

Paper Novel strategies for anti-aging drug discovery.

Saraswat, Komal; Rizvi, Syed Ibrahim · 2017 · Expert opinion on drug discovery · DOI

Full title: Novel strategies for anti-aging drug discovery.

Authors: Saraswat, Komal; Rizvi, Syed Ibrahim

Year: 2017

Venue: Expert opinion on drug discovery

DOI: https://doi.org/10.1080/17460441.2017.1349750

Paper Effects of anti-aging interventions on intestinal microbiota.

Du, Yanjiao; Gao, Yue; Zeng, Bo et al. · 2021 · Gut microbes · DOI

Full title: Effects of anti-aging interventions on intestinal microbiota.

Authors: Du, Yanjiao; Gao, Yue; Zeng, Bo; Fan, Xiaolan; Yang, Deying; Yang, Mingyao

Year: 2021

Venue: Gut microbes

DOI: https://doi.org/10.1080/19490976.2021.1994835

Paper Model organism life extending therapeutics modulate diverse nodes in the drug-gene-microbe tripartite human longevity interactome.

Salekeen, Rahagir; Lustgarten, Michael S; Khan, Umama et al. · 2024 · Journal of biomolecular structure & dynamics · DOI

Full title: Model organism life extending therapeutics modulate diverse nodes in the drug-gene-microbe tripartite human longevity interactome.

Authors: Salekeen, Rahagir; Lustgarten, Michael S; Khan, Umama; Islam, Kazi Mohammed Didarul

Year: 2024

Venue: Journal of biomolecular structure & dynamics

DOI: https://doi.org/10.1080/07391102.2023.2192823

Paper Is anti-ageing drug discovery becoming a reality?

A. Moskalev · 2019 · Expert Opinion on Drug Discovery · DOI

Full title: Is anti-ageing drug discovery becoming a reality?

Authors: A. Moskalev

Year: 2019

Venue: Expert Opinion on Drug Discovery

DOI: https://doi.org/10.1080/17460441.2020.1702965

Paper From population science to the clinic? Limits of epigenetic clocks as personal biomarkers.

Apsley, Abner T; Etzel, Laura; Ye, Qiaofeng et al. · 2025 · Epigenomics · DOI

Full title: From population science to the clinic? Limits of epigenetic clocks as personal biomarkers.

Authors: Apsley, Abner T; Etzel, Laura; Ye, Qiaofeng; Shalev, Idan

Year: 2025

Venue: Epigenomics

DOI: https://doi.org/10.1080/17501911.2025.2603880

Paper A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer.

Di Tano, Maira; Longo, Valter D · 2020 · Molecular & cellular oncology · DOI

Full title: A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer.

Authors: Di Tano, Maira; Longo, Valter D

Year: 2020

Venue: Molecular & cellular oncology

DOI: https://doi.org/10.1080/23723556.2020.1791671

Paper Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset.

Fernandez, Elizabeth; Ross, Corinna; Liang, Hanyu et al. · 2019 · Pathobiology of aging & age related diseases · DOI

Full title: Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset.

Authors: Fernandez, Elizabeth; Ross, Corinna; Liang, Hanyu; Javors, Martin; Tardif, Suzette; Salmon, Adam B

Year: 2019

Venue: Pathobiology of aging & age related diseases

DOI: https://doi.org/10.1080/20010001.2019.1657756

Paper Pharmacological Inhibition of Phosphoinositide 3 and TOR Kinases Improves Survival of Drosophila melanogaster

A. Moskalev; M. Shaposhnikov · 2010 · Rejuvenation Research · DOI

Full title: Pharmacological Inhibition of Phosphoinositide 3 and TOR Kinases Improves Survival of Drosophila melanogaster

Authors: A. Moskalev; M. Shaposhnikov

Year: 2010

Venue: Rejuvenation Research

DOI: https://doi.org/10.1089/rej.2009.0903

Paper Gut microbiota mediates the inhibition of lymphopoiesis in dietary-restricted mice by suppressing glycolysis

Si Tao; Yiting Wang; Chenghui Yu et al. · 2022 · Gut microbes · DOI

Full title: Gut microbiota mediates the inhibition of lymphopoiesis in dietary-restricted mice by suppressing glycolysis

Authors: Si Tao; Yiting Wang; Chenghui Yu; Rongrong Qiu; Yanshan Jiang; J. Jia; Zhendong Tao; Liu Zhang; B. Zou; Duozhuang Tang

Year: 2022

Venue: Gut microbes

DOI: https://doi.org/10.1080/19490976.2022.2117509

Paper Polyphenols as Potential Geroprotectors.

Proshkina, Ekaterina; Koval, Liubov; Platonova, Elena et al. · 2024 · Antioxidants & redox signaling · DOI

Full title: Polyphenols as Potential Geroprotectors.

Authors: Proshkina, Ekaterina; Koval, Liubov; Platonova, Elena; Golubev, Denis; Ulyasheva, Natalia; Babak, Tatyana; Shaposhnikov, Mikhail; Moskalev, Alexey

Year: 2024

Venue: Antioxidants & redox signaling

DOI: https://doi.org/10.1089/ars.2023.0247

Paper Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions

Theodore T. Ho; Paul V. Dellorusso; E. Verovskaya et al. · 2021 · Journal of Experimental Medicine · DOI

Full title: Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions

Authors: Theodore T. Ho; Paul V. Dellorusso; E. Verovskaya; Sietske T Bakker; J. Flach; Lucas K. Smith; P. Ventura; Olivia M Lansinger; A. Hérault; S. Zhang; Yoon-A Kang; Carl A. Mitchell; Saul A. Villeda; E. Passegué

Year: 2021

Venue: Journal of Experimental Medicine

DOI: https://doi.org/10.1084/jem.20210223

Paper Epigenetic engineering and its possible role in anti-aging intervention.

Vaiserman, Alexander M · 2008 · Rejuvenation research · DOI

Full title: Epigenetic engineering and its possible role in anti-aging intervention.

Authors: Vaiserman, Alexander M

Year: 2008

Venue: Rejuvenation research

DOI: https://doi.org/10.1089/rej.2007.0579

Paper The emerging role of geropathology in preclinical aging studies

W. Ladiges · 2017 · Pathobiology of Aging & Age-related Diseases · DOI

Full title: The emerging role of geropathology in preclinical aging studies

Authors: W. Ladiges

Year: 2017

Venue: Pathobiology of Aging & Age-related Diseases

DOI: https://doi.org/10.1080/20010001.2017.1304005

Paper Metformin as a geroprotector.

Bulterijs, Sven · 2011 · Rejuvenation research · DOI

Full title: Metformin as a geroprotector.

Authors: Bulterijs, Sven

Year: 2011

Venue: Rejuvenation research

DOI: https://doi.org/10.1089/rej.2011.1153

Paper β-Nicotinamide Monucleotide Supplement with Astaxanthin and Blood Orange Enhanced NAD+ Bioavailability and Mitigated Age-Associated Physiological Decline in Zebrafish

Doris Zhang; Lynn Zhao; Lotus Wong · 2022 · Current Developments in Nutrition · DOI

Full title: β-Nicotinamide Monucleotide Supplement with Astaxanthin and Blood Orange Enhanced NAD+ Bioavailability and Mitigated Age-Associated Physiological Decline in Zebrafish

Authors: Doris Zhang; Lynn Zhao; Lotus Wong

Year: 2022

Venue: Current Developments in Nutrition

DOI: https://doi.org/10.1093/cdn/nzac047.054

Paper Unraveling the links between cancer and aging.

Serrano, Manuel · 2016 · Carcinogenesis · DOI

Full title: Unraveling the links between cancer and aging.

Authors: Serrano, Manuel

Year: 2016

Venue: Carcinogenesis

DOI: https://doi.org/10.1093/carcin/bgv100

Paper New Horizons in cellular senescence for clinicians.

Witham, Miles D; Granic, Antoneta; Miwa, Satomi et al. · 2023 · Age and ageing · DOI

Full title: New Horizons in cellular senescence for clinicians.

Authors: Witham, Miles D; Granic, Antoneta; Miwa, Satomi; Passos, Joao F; Richardson, Gavin D; Sayer, Avan A

Year: 2023

Venue: Age and ageing

DOI: https://doi.org/10.1093/ageing/afad127

Paper Anti-senescence therapies: a new concept to address cardiovascular disease.

Stojanović, Stevan D; Thum, Thomas; Bauersachs, Johann · 2025 · Cardiovascular research · DOI

Full title: Anti-senescence therapies: a new concept to address cardiovascular disease.

Authors: Stojanović, Stevan D; Thum, Thomas; Bauersachs, Johann

Year: 2025

Venue: Cardiovascular research

DOI: https://doi.org/10.1093/cvr/cvaf030

Paper Anti-ageing interventions for the treatment of cardiovascular disease.

Abdellatif, Mahmoud; Schmid, Sophie T; Fuerlinger, Alexander et al. · 2025 · Cardiovascular research · DOI

Full title: Anti-ageing interventions for the treatment of cardiovascular disease.

Authors: Abdellatif, Mahmoud; Schmid, Sophie T; Fuerlinger, Alexander; Kroemer, Guido

Year: 2025

Venue: Cardiovascular research

DOI: https://doi.org/10.1093/cvr/cvae177

Paper Effect of age and caloric restriction on cutaneous wound closure in rats and monkeys.

Roth, G S; Kowatch, M A; Hengemihle, J et al. · 1997 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Effect of age and caloric restriction on cutaneous wound closure in rats and monkeys.

Authors: Roth, G S; Kowatch, M A; Hengemihle, J; Ingram, D K; Spangler, E L; Johnson, L K; Lane, M A

Year: 1997

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/52a.2.b98

Paper Yeast as a tool to identify anti-aging compounds

Zimmermann, Andreas; Hofer, Sebastian J.; Pendl, Tobias et al. · 2018 · FEMS Yeast Research · DOI

Full title: Yeast as a tool to identify anti-aging compounds

Authors: Zimmermann, Andreas; Hofer, Sebastian J.; Pendl, Tobias; Kainz, Katharina; Madeo, Frank; Carmona‐Gutiérrez, Didac

Year: 2018

Venue: FEMS Yeast Research

DOI: https://doi.org/10.1093/femsyr/foy020

Paper Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop.

Espinoza, Sara E; Khosla, Sundeep; Baur, Joseph A et al. · 2023 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop.

Authors: Espinoza, Sara E; Khosla, Sundeep; Baur, Joseph A; de Cabo, Rafael; Musi, Nicolas

Year: 2023

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glad034

Paper DNA methylation as a biomarker for cardiometabolic disease risk

J. Janovska; U. Nixdorff; J. Voicehovska · 2023 · European Journal of Preventive Cardiology · DOI

Full title: DNA methylation as a biomarker for cardiometabolic disease risk

Authors: J. Janovska; U. Nixdorff; J. Voicehovska

Year: 2023

Venue: European Journal of Preventive Cardiology

DOI: https://doi.org/10.1093/eurjpc/zwad125.010

Paper Redox-based Disruption of Cellular Hormesis and Promotion of Degenerative Pathways: Perspectives on Aging Processes.

Bevere, Michele; Di Cola, Giulia; Santangelo, Carmen et al. · 2022 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Redox-based Disruption of Cellular Hormesis and Promotion of Degenerative Pathways: Perspectives on Aging Processes.

Authors: Bevere, Michele; Di Cola, Giulia; Santangelo, Carmen; Grazioli, Elisa; Marramiero, Lorenzo; Pignatelli, Pamela; Bondi, Danilo; Mrakic-Sposta, Simona

Year: 2022

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glac167

Paper Dynamical Network Stability Analysis of Multiple Biological Ages Provides a Framework for Understanding the Aging Process

G. Pridham; A. Rutenberg · 2023 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Dynamical Network Stability Analysis of Multiple Biological Ages Provides a Framework for Understanding the Aging Process

Authors: G. Pridham; A. Rutenberg

Year: 2023

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glae021

Paper Metformin protects against inflammation, oxidative stress to delay poly I:C-induced aging-like phenomena in gut of an annual fish.

Shasha Li; Yanhan Hou; Keke Liu et al. · 2021 · The journals of gerontology. Series A, Biological sciences and medical sciences · DOI

Full title: Metformin protects against inflammation, oxidative stress to delay poly I:C-induced aging-like phenomena in gut of an annual fish.

Authors: Shasha Li; Yanhan Hou; Keke Liu; Hongyan Zhu; Mengxue Qiao; Xiaowen Sun; Guorong Li

Year: 2021

Venue: The journals of gerontology. Series A, Biological sciences and medical sciences

DOI: https://doi.org/10.1093/gerona/glab298

Paper Prediction of biological age and evaluation of genome-wide dynamic methylomic changes throughout human aging

Roudbar, Mahmoud Amiri; Mousavi, Seyedeh Fatemeh; Ardestani, Siavash Salek et al. · 2021 · G3 Genes Genomes Genetics · DOI

Full title: Prediction of biological age and evaluation of genome-wide dynamic methylomic changes throughout human aging

Authors: Roudbar, Mahmoud Amiri; Mousavi, Seyedeh Fatemeh; Ardestani, Siavash Salek; Lopes, Fernando Brito; Momen, Mehdi; Gianola, Daniel; Khatib, Hasan

Year: 2021

Venue: G3 Genes Genomes Genetics

DOI: https://doi.org/10.1093/g3journal/jkab112

Paper Metabolic Regulation of Longevity by Flavin-containing Monooxygenase 2

Choi, Christopher Y. · 2022 · Deep Blue (University of Michigan) · DOI

Full title: Metabolic Regulation of Longevity by Flavin-containing Monooxygenase 2

Authors: Choi, Christopher Y.

Year: 2022

Venue: Deep Blue (University of Michigan)

DOI: https://doi.org/10.7302/6251

Paper Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging

Ryoei Uchida; Yoshimasa Saito; Kazuki Nogami et al. · 2018 · npj Aging and Mechanisms of Disease · DOI

Full title: Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging

Authors: Ryoei Uchida; Yoshimasa Saito; Kazuki Nogami; Yohei Kajiyama; Yukana Suzuki; Yasuhiro Kawase; Toshiaki Nakaoka; T. Muramatsu; M. Kimura; H. Saito

Year: 2018

Venue: npj Aging and Mechanisms of Disease

DOI: https://doi.org/10.1038/s41514-018-0031-5

Paper Cellular senescence: the good, the bad and the unknown.

Huang, Weijun; Hickson, LaTonya J; Eirin, Alfonso et al. · 2022 · Nature reviews. Nephrology · DOI

Full title: Cellular senescence: the good, the bad and the unknown.

Authors: Huang, Weijun; Hickson, LaTonya J; Eirin, Alfonso; Kirkland, James L; Lerman, Lilach O

Year: 2022

Venue: Nature reviews. Nephrology

DOI: https://doi.org/10.1038/s41581-022-00601-z

Paper Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in mice

Kiyoshi Yoshioka; Takumi Sugimoto; Mamoru Oyabu et al. · 2025 · npj Aging · DOI

Full title: Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in mice

Authors: Kiyoshi Yoshioka; Takumi Sugimoto; Mamoru Oyabu; Naoki Ito; Aoi Kodama; Yasutomi Kamei; Shin-ichiro Imai

Year: 2025

Venue: npj Aging

DOI: https://doi.org/10.1038/s41514-025-00297-y

Paper Translating cellular senescence research into clinical practice for metabolic disease.

Chaib, Selim; Palmer, Allyson K; Wyles, Saranya P et al. · 2026 · Nature reviews. Endocrinology · DOI

Full title: Translating cellular senescence research into clinical practice for metabolic disease.

Authors: Chaib, Selim; Palmer, Allyson K; Wyles, Saranya P; Musi, Nicolas; Kirkland, James L; Tchkonia, Tamara

Year: 2026

Venue: Nature reviews. Endocrinology

DOI: https://doi.org/10.1038/s41574-025-01187-9

Paper Cellular senescence and senolytics: the path to the clinic.

Chaib, Selim; Tchkonia, Tamar; Kirkland, James L · 2022 · Nature medicine · DOI

Full title: Cellular senescence and senolytics: the path to the clinic.

Authors: Chaib, Selim; Tchkonia, Tamar; Kirkland, James L

Year: 2022

Venue: Nature medicine

DOI: https://doi.org/10.1038/s41591-022-01923-y

Paper A toolbox for the longitudinal assessment of healthspan in aging mice.

Bellantuono, I; de Cabo, R; Ehninger, D et al. · 2020 · Nature protocols · DOI

Full title: A toolbox for the longitudinal assessment of healthspan in aging mice.

Authors: Bellantuono, I; de Cabo, R; Ehninger, D; Di Germanio, C; Lawrie, A; Miller, J; Mitchell, S J; Navas-Enamorado, I; Potter, P K; Tchkonia, T; Trejo, J L; Lamming, D W

Year: 2020

Venue: Nature protocols

DOI: https://doi.org/10.1038/s41596-019-0256-1

Paper The relationship between epigenetic age and the hallmarks of aging in human cells

Kabacik, Sylwia; Lowe, Donna; Fransen, Leonie Francina Hendrina et al. · 2022 · Nature Aging · DOI

Full title: The relationship between epigenetic age and the hallmarks of aging in human cells

Authors: Kabacik, Sylwia; Lowe, Donna; Fransen, Leonie Francina Hendrina; Leonard, Martin O.; Ang, Siew‐Lan; Whiteman, Christopher; Corsi, Sarah; Cohen, Howard; Felton, Sarah; Bali, Radhika; Horvath, Steve; Raj, Ken

Year: 2022

Venue: Nature Aging

DOI: https://doi.org/10.1038/s43587-022-00220-0

Paper A senolytic strategy integrating multiple technologies delays aging.

· 2023 · Nature aging · DOI

Full title: A senolytic strategy integrating multiple technologies delays aging.

Year: 2023

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-023-00369-2

Paper Targeting the biology of aging with mTOR inhibitors

Mannick, Joan B.; Lamming, Dudley W. · 2023 · Nature Aging · DOI

Full title: Targeting the biology of aging with mTOR inhibitors

Authors: Mannick, Joan B.; Lamming, Dudley W.

Year: 2023

Venue: Nature Aging

DOI: https://doi.org/10.1038/s43587-023-00416-y

Paper Nature of epigenetic aging from a single-cell perspective.

Tarkhov, Andrei E; Lindstrom-Vautrin, Thomas; Zhang, Sirui et al. · 2024 · Nature aging · DOI

Full title: Nature of epigenetic aging from a single-cell perspective.

Authors: Tarkhov, Andrei E; Lindstrom-Vautrin, Thomas; Zhang, Sirui; Ying, Kejun; Moqri, Mahdi; Zhang, Bohan; Tyshkovskiy, Alexander; Levy, Orr; Gladyshev, Vadim N

Year: 2024

Venue: Nature aging

DOI: https://doi.org/10.1038/s43587-024-00616-0

Paper Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity.

Ukraintseva, Svetlana; Arbeev, Konstantin; Duan, Matt et al. · 2021 · Mechanisms of ageing and development · DOI

Full title: Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity.

Authors: Ukraintseva, Svetlana; Arbeev, Konstantin; Duan, Matt; Akushevich, Igor; Kulminski, Alexander; Stallard, Eric; Yashin, Anatoliy

Year: 2021

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2020.111418

Paper Modelling physical resilience in ageing mice.

Schosserer, Markus; Banks, Gareth; Dogan, Soner et al. · 2019 · Mechanisms of ageing and development · DOI

Full title: Modelling physical resilience in ageing mice.

Authors: Schosserer, Markus; Banks, Gareth; Dogan, Soner; Dungel, Peter; Fernandes, Adelaide; Marolt Presen, Darja; Matheu, Ander; Osuchowski, Marcin; Potter, Paul; Sanfeliu, Coral; Tuna, Bilge Guvenc; Varela-Nieto, Isabel; Bellantuono, Ilaria

Year: 2019

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2018.10.001

Paper Effect of senolytic drugs in young female mice chemically induced to estropause.

Ávila, Bianca M; Zanini, Bianka M; Luduvico, Karina P et al. · 2024 · Life sciences · DOI

Full title: Effect of senolytic drugs in young female mice chemically induced to estropause.

Authors: Ávila, Bianca M; Zanini, Bianka M; Luduvico, Karina P; Oliveira, Thais L; Hense, Jéssica D; Garcia, Driele N; Prosczek, Juliane; Stefanello, Francieli M; da Cruz, Pedro H; Giongo, Janice L; Vaucher, Rodrigo A; Mason, Jeffrey B; Masternak, Michal M; Schneider, Augusto

Year: 2024

Venue: Life sciences

DOI: https://doi.org/10.1016/j.lfs.2024.123073

Paper C. elegans screening strategies to identify pro-longevity interventions.

Maglioni, Silvia; Arsalan, Nayna; Ventura, Natascia · 2016 · Mechanisms of ageing and development · DOI

Full title: C. elegans screening strategies to identify pro-longevity interventions.

Authors: Maglioni, Silvia; Arsalan, Nayna; Ventura, Natascia

Year: 2016

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2016.07.010

Paper The use of geroprotectors to prevent multimorbidity: Opportunities and challenges.

Morsli, Samir; Bellantuono, Ilaria · 2021 · Mechanisms of ageing and development · DOI

Full title: The use of geroprotectors to prevent multimorbidity: Opportunities and challenges.

Authors: Morsli, Samir; Bellantuono, Ilaria

Year: 2021

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2020.111391

Paper Gender-specific effects of pro-longevity interventions in Drosophila.

Lushchak, Oleh; Strilbytska, Olha; Storey, Kenneth B · 2023 · Mechanisms of ageing and development · DOI

Full title: Gender-specific effects of pro-longevity interventions in Drosophila.

Authors: Lushchak, Oleh; Strilbytska, Olha; Storey, Kenneth B

Year: 2023

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2022.111754

Paper Current senolytics: Mode of action, efficacy and limitations, and their future.

Rad, Amirhossein Nayeri; Grillari, Johannes · 2024 · Mechanisms of ageing and development · DOI

Full title: Current senolytics: Mode of action, efficacy and limitations, and their future.

Authors: Rad, Amirhossein Nayeri; Grillari, Johannes

Year: 2024

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2023.111888

Paper Insights into targeting cellular senescence with senolytic therapy: The journey from preclinical trials to clinical practice.

Chen, Peng; Wang, Yulai; Zhou, Benhong · 2024 · Mechanisms of ageing and development · DOI

Full title: Insights into targeting cellular senescence with senolytic therapy: The journey from preclinical trials to clinical practice.

Authors: Chen, Peng; Wang, Yulai; Zhou, Benhong

Year: 2024

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2024.111918

Paper The involvement of macroautophagy in aging and anti-aging interventions.

Donati, Alessio · 2006 · Molecular aspects of medicine · DOI

Full title: The involvement of macroautophagy in aging and anti-aging interventions.

Authors: Donati, Alessio

Year: 2006

Venue: Molecular aspects of medicine

DOI: https://doi.org/10.1016/j.mam.2006.08.003

Paper Liver aging: underlying mechanisms and therapeutic strategies.

Zhong, Ling; Wang, Liu; Syed, Jibran Nehal et al. · 2025 · Molecular aspects of medicine · DOI

Full title: Liver aging: underlying mechanisms and therapeutic strategies.

Authors: Zhong, Ling; Wang, Liu; Syed, Jibran Nehal; Yang, Jielin; Zhang, Yuwei

Year: 2025

Venue: Molecular aspects of medicine

DOI: https://doi.org/10.1016/j.mam.2025.101397

Paper Recent advances in the discovery of senolytics.

Zhang, Lei; Pitcher, Louise E; Prahalad, Vaishali et al. · 2021 · Mechanisms of ageing and development · DOI

Full title: Recent advances in the discovery of senolytics.

Authors: Zhang, Lei; Pitcher, Louise E; Prahalad, Vaishali; Niedernhofer, Laura J; Robbins, Paul D

Year: 2021

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2021.111587

Paper In the land of not-unhappiness: On the state-of-the-art of targeting aging and age-related diseases by biomedical research.

Klinaki, Eirini; Ogrodnik, Mikolaj · 2024 · Mechanisms of ageing and development · DOI

Full title: In the land of not-unhappiness: On the state-of-the-art of targeting aging and age-related diseases by biomedical research.

Authors: Klinaki, Eirini; Ogrodnik, Mikolaj

Year: 2024

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2024.111929

Paper Skeletal muscle aging, cellular senescence, and senotherapeutics: Current knowledge and future directions.

Englund, Davis A; Zhang, Xu; Aversa, Zaira et al. · 2021 · Mechanisms of ageing and development · DOI

Full title: Skeletal muscle aging, cellular senescence, and senotherapeutics: Current knowledge and future directions.

Authors: Englund, Davis A; Zhang, Xu; Aversa, Zaira; LeBrasseur, Nathan K

Year: 2021

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2021.111595

Paper The NR4A nuclear receptors as potential targets for anti-aging interventions.

Paillasse, Michael R; de Medina, Philippe · 2015 · Medical hypotheses · DOI

Full title: The NR4A nuclear receptors as potential targets for anti-aging interventions.

Authors: Paillasse, Michael R; de Medina, Philippe

Year: 2015

Venue: Medical hypotheses

DOI: https://doi.org/10.1016/j.mehy.2014.12.003

Paper Rodent diet aids and the fallacy of caloric restriction.

Wolf, Alexander M · 2021 · Mechanisms of ageing and development · DOI

Full title: Rodent diet aids and the fallacy of caloric restriction.

Authors: Wolf, Alexander M

Year: 2021

Venue: Mechanisms of ageing and development

DOI: https://doi.org/10.1016/j.mad.2021.111584

Paper Chronic inflammation and the hallmarks of aging.

Baechle, Jordan J; Chen, Nan; Makhijani, Priya et al. · 2023 · Molecular metabolism · DOI

Full title: Chronic inflammation and the hallmarks of aging.

Authors: Baechle, Jordan J; Chen, Nan; Makhijani, Priya; Winer, Shawn; Furman, David; Winer, Daniel A

Year: 2023

Venue: Molecular metabolism

DOI: https://doi.org/10.1016/j.molmet.2023.101755

Paper Mini-review: Retarding aging in murine genetic models of neurodegeneration.

Albin, Roger L; Miller, Richard A · 2016 · Neurobiology of disease · DOI

Full title: Mini-review: Retarding aging in murine genetic models of neurodegeneration.

Authors: Albin, Roger L; Miller, Richard A

Year: 2016

Venue: Neurobiology of disease

DOI: https://doi.org/10.1016/j.nbd.2015.10.014

Paper Targeting cellular senescence in metabolic disease.

Palmer, Allyson K; Tchkonia, Tamar; Kirkland, James L · 2022 · Molecular metabolism · DOI

Full title: Targeting cellular senescence in metabolic disease.

Authors: Palmer, Allyson K; Tchkonia, Tamar; Kirkland, James L

Year: 2022

Venue: Molecular metabolism

DOI: https://doi.org/10.1016/j.molmet.2022.101601

Paper Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice.

Lérida-Viso, Araceli; Estepa-Fernández, Alejandra; Morellá-Aucejo, Ángela et al. · 2022 · Pharmacological research · DOI

Full title: Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice.

Authors: Lérida-Viso, Araceli; Estepa-Fernández, Alejandra; Morellá-Aucejo, Ángela; Lozano-Torres, Beatriz; Alfonso, María; Blandez, Juan F; Bisbal, Viviana; Sepúlveda, Pilar; García-Fernández, Alba; Orzáez, Mar; Martínez-Máñez, Ramón

Year: 2022

Venue: Pharmacological research

DOI: https://doi.org/10.1016/j.phrs.2022.106356

Paper The role of DNA methylation in epigenetics of aging.

Unnikrishnan, Archana; Freeman, Willard M; Jackson, Jordan et al. · 2019 · Pharmacology & therapeutics · DOI

Full title: The role of DNA methylation in epigenetics of aging.

Authors: Unnikrishnan, Archana; Freeman, Willard M; Jackson, Jordan; Wren, Jonathan D; Porter, Hunter; Richardson, Arlan

Year: 2019

Venue: Pharmacology & therapeutics

DOI: https://doi.org/10.1016/j.pharmthera.2018.11.001

Paper Advances in mass spectrometry-based multi-scale metabolomic methodologies and their applications in biological and clinical investigations.

Ziyi Wang; Hongying Zhu; Wei Xiong · 2023 · Science Bulletin · DOI

Full title: Advances in mass spectrometry-based multi-scale metabolomic methodologies and their applications in biological and clinical investigations.

Authors: Ziyi Wang; Hongying Zhu; Wei Xiong

Year: 2023

Venue: Science Bulletin

DOI: https://doi.org/10.1016/j.scib.2023.08.047

Paper Senolytics prevent age-associated changes in female mice brain.

Faria, Olivia Wyse; de Aguiar, Mayara Sandrielly Soares; de Mello, Julia Eisenhardt et al. · 2024 · Neuroscience letters · DOI

Full title: Senolytics prevent age-associated changes in female mice brain.

Authors: Faria, Olivia Wyse; de Aguiar, Mayara Sandrielly Soares; de Mello, Julia Eisenhardt; Alvez, Fernando Lopez; Luduvico, Karina Pereira; Garcia, Driele Neske; Schneider, Augusto; Masternak, Michal M; Spanevello, Roselia Maria; Stefanello, Francieli Moro

Year: 2024

Venue: Neuroscience letters

DOI: https://doi.org/10.1016/j.neulet.2024.137730

Paper A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.

S. Imai · 2010 · Pharmacological Research · DOI

Full title: A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.

Authors: S. Imai

Year: 2010

Venue: Pharmacological Research

DOI: https://doi.org/10.1016/j.phrs.2010.01.006

Paper Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice.

Fu, Zidong Donna; Klaassen, Curtis D · 2014 · Toxicology and applied pharmacology · DOI

Full title: Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice.

Authors: Fu, Zidong Donna; Klaassen, Curtis D

Year: 2014

Venue: Toxicology and applied pharmacology

DOI: https://doi.org/10.1016/j.taap.2013.11.003

Paper Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice

Fu, Zidong Donna; Klaassen, Curtis D. · 2013 · Toxicology and Applied Pharmacology · DOI

Full title: Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice

Authors: Fu, Zidong Donna; Klaassen, Curtis D.

Year: 2013

Venue: Toxicology and Applied Pharmacology

DOI: https://doi.org/10.1016/j.taap.2013.10.020

Paper A Senescence-Centric View of Aging: Implications for Longevity and Disease.

Borghesan, M; Hoogaars, W M H; Varela-Eirin, M et al. · 2020 · Trends in cell biology · DOI

Full title: A Senescence-Centric View of Aging: Implications for Longevity and Disease.

Authors: Borghesan, M; Hoogaars, W M H; Varela-Eirin, M; Talma, N; Demaria, M

Year: 2020

Venue: Trends in cell biology

DOI: https://doi.org/10.1016/j.tcb.2020.07.002

Paper Effects of melatonin on a d-galactose-induced male reproductive aging mouse model.

Lee, Won-Young; Sim, Heyon Woo; Park, Hyun Jung · 2023 · Theriogenology · DOI

Full title: Effects of melatonin on a d-galactose-induced male reproductive aging mouse model.

Authors: Lee, Won-Young; Sim, Heyon Woo; Park, Hyun Jung

Year: 2023

Venue: Theriogenology

DOI: https://doi.org/10.1016/j.theriogenology.2023.05.001

Paper Using light to drive energy transduction in metazoan aging.

Tiwary, Vaibhav; Galow, Anne-Marie; Wojtovich, Andrew P et al. · 2023 · Trends in biochemical sciences · DOI

Full title: Using light to drive energy transduction in metazoan aging.

Authors: Tiwary, Vaibhav; Galow, Anne-Marie; Wojtovich, Andrew P; Peleg, Shahaf

Year: 2023

Venue: Trends in biochemical sciences

DOI: https://doi.org/10.1016/j.tibs.2023.08.010

Paper Biotechnology, bioethics and anti-aging interventions.

Turner, Leigh · 2004 · Trends in biotechnology · DOI

Full title: Biotechnology, bioethics and anti-aging interventions.

Authors: Turner, Leigh

Year: 2004

Venue: Trends in biotechnology

DOI: https://doi.org/10.1016/j.tibtech.2004.03.008

Paper Geroneuroprotectors: Effective Geroprotectors for the Brain.

Schubert, David; Currais, Antonio; Goldberg, Joshua et al. · 2018 · Trends in pharmacological sciences · DOI

Full title: Geroneuroprotectors: Effective Geroprotectors for the Brain.

Authors: Schubert, David; Currais, Antonio; Goldberg, Joshua; Finley, Kim; Petrascheck, Michael; Maher, Pamela

Year: 2018

Venue: Trends in pharmacological sciences

DOI: https://doi.org/10.1016/j.tips.2018.09.008

Paper Targeting aging mechanisms: pharmacological perspectives.

Moskalev, Alexey; Guvatova, Zulfiya; Lopes, Ines De Almeida et al. · 2022 · Trends in endocrinology and metabolism: TEM · DOI

Full title: Targeting aging mechanisms: pharmacological perspectives.

Authors: Moskalev, Alexey; Guvatova, Zulfiya; Lopes, Ines De Almeida; Beckett, Charles W; Kennedy, Brian K; De Magalhaes, Joao Pedro; Makarov, Alexander A

Year: 2022

Venue: Trends in endocrinology and metabolism: TEM

DOI: https://doi.org/10.1016/j.tem.2022.01.007

Paper Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Imai, Shin‐ichiro; Guarente, Leonard · 2010 · Trends in Pharmacological Sciences · DOI

Full title: Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Authors: Imai, Shin‐ichiro; Guarente, Leonard

Year: 2010

Venue: Trends in Pharmacological Sciences

DOI: https://doi.org/10.1016/j.tips.2010.02.003

Paper Faculty Opinions recommendation of Promoting health and longevity through diet: from model organisms to humans.

Müller, Roman‐Ulrich · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · DOI

Full title: Faculty Opinions recommendation of Promoting health and longevity through diet: from model organisms to humans.

Authors: Müller, Roman‐Ulrich

Year: 2020

Venue: Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI: https://doi.org/10.3410/f.725409572.793572493

Paper Faculty Opinions recommendation of Reduced cytosolic protein synthesis suppresses mitochondrial degeneration.

Nairn, Angus C.; Wiseman, Shari · 2008 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · DOI

Full title: Faculty Opinions recommendation of Reduced cytosolic protein synthesis suppresses mitochondrial degeneration.

Authors: Nairn, Angus C.; Wiseman, Shari

Year: 2008

Venue: Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI: https://doi.org/10.3410/f.720227198.580533

Paper Faculty Opinions recommendation of Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension.

Müller, Roman‐Ulrich · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · DOI

Full title: Faculty Opinions recommendation of Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension.

Authors: Müller, Roman‐Ulrich

Year: 2020

Venue: Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI: https://doi.org/10.3410/f.736691002.793572463

Paper Faculty Opinions recommendation of NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.

Serrano, Ramón · 2009 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · DOI

Full title: Faculty Opinions recommendation of NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.

Authors: Serrano, Ramón

Year: 2009

Venue: Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

DOI: https://doi.org/10.3410/f.1166555.627562

Paper - **DOI:** 10.34922/ae.2025.38.3.007 - **Authors:** И А Соловьёв, Д А Голубев - **Year:** 2025 - **Journal:** Успехи геронтологии

Шевченко Оксана Ивановна; Кодинец Ирина Николаевна; Катаманова Елена Владимировна et al. · 2011 · Успехи геронтологии · DOI

Full title: - **DOI:** 10.34922/ae.2025.38.3.007 - **Authors:** И А Соловьёв, Д А Голубев - **Year:** 2025 - **Journal:** Успехи геронтологии

Year: 2011

Venue: Успехи геронтологии

DOI: https://doi.org/10.34922/ae.2025.38.3.007

Paper Untitled

Liu, Xuqian, Huang, Taosheng, Huang, Fraga, M, Agrelo, R, Esteller, M, Fraga, M, Esteller, M, Braidy, N, Grant, R, Sachdev, P, Fuellen, G, Jansen, L, Cohen, A, Luyten, Walter, Gogol, Manfred, Hosseini, L, Vafaee, M, Mahmoudi, J, Badalzadeh, R, Ying, W, Zhang, M, Ying, Mouchiroud, L, Houtkooper, R, Moullan, N, Katsyuba, E, Ryu, D, Stein, L, Imai, S, Houtkooper, R, Pirinen, E, Auwerx, J, Katsyuba, E, Auwerx, J, Tanno, M, Sakamoto, J, Miura, T, Shimamoto, K, Horio, Y, Satoh, A, Brace, C, Rensing, N, Cliften, P, Wozniak, D, Kim, M, Zhang, T, Kraus, W, Bai, P, Canto, C, Oudart, H, Brunynszki, Attila, Cen, Yana, Pereira, Camacho, Tarrago, J, Chini, M, Nin, Ccs, Escande, V, C, Trammell, S, Yu, L, Redpath, P, Migaud, M, Brenner, C, Bogan, K, Brenner, C, Ummarino, S, Mozzon, M, Zamporlini, F, Amici, A, Mazzola, F, Mills, K, Yoshida, S, Stein, L, Grozio, A, Kubota, S, Chaturvedi, P, Tyagi, S, Igarashi, M, Miura, M, Williams, E, Jaksch, F, Kadowaki, T, Chini, E, Chini, Ccs, Netto, Espindola, Oliveira, J De, Schooten, G Van, W, Yoshino, J, Baur, J, Imai, S, Zhang, H, Ryu, D, Wu, Y, Gariani, K, Wang, X, Tarantini, S, Valcarcel-Ares, M, Toth, P · 2019 · American Journal of Biomedical Science & Research · DOI

Full title: Untitled

Authors: Liu, Xuqian, Huang, Taosheng, Huang, Fraga, M, Agrelo, R, Esteller, M, Fraga, M, Esteller, M, Braidy, N, Grant, R, Sachdev, P, Fuellen, G, Jansen, L, Cohen, A, Luyten, Walter, Gogol, Manfred, Hosseini, L, Vafaee, M, Mahmoudi, J, Badalzadeh, R, Ying, W, Zhang, M, Ying, Mouchiroud, L, Houtkooper, R, Moullan, N, Katsyuba, E, Ryu, D, Stein, L, Imai, S, Houtkooper, R, Pirinen, E, Auwerx, J, Katsyuba, E, Auwerx, J, Tanno, M, Sakamoto, J, Miura, T, Shimamoto, K, Horio, Y, Satoh, A, Brace, C, Rensing, N, Cliften, P, Wozniak, D, Kim, M, Zhang, T, Kraus, W, Bai, P, Canto, C, Oudart, H, Brunynszki, Attila, Cen, Yana, Pereira, Camacho, Tarrago, J, Chini, M, Nin, Ccs, Escande, V, C, Trammell, S, Yu, L, Redpath, P, Migaud, M, Brenner, C, Bogan, K, Brenner, C, Ummarino, S, Mozzon, M, Zamporlini, F, Amici, A, Mazzola, F, Mills, K, Yoshida, S, Stein, L, Grozio, A, Kubota, S, Chaturvedi, P, Tyagi, S, Igarashi, M, Miura, M, Williams, E, Jaksch, F, Kadowaki, T, Chini, E, Chini, Ccs, Netto, Espindola, Oliveira, J De, Schooten, G Van, W, Yoshino, J, Baur, J, Imai, S, Zhang, H, Ryu, D, Wu, Y, Gariani, K, Wang, X, Tarantini, S, Valcarcel-Ares, M, Toth, P

Year: 2019

Venue: American Journal of Biomedical Science & Research

DOI: https://doi.org/10.34297/ajbsr.6.5

Paper BIOLOGICAL AGE: METHODOLOGY FOR DETERMINING

A. Pisaruk; N. Koshel · 2021 · JOURNAL OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE · DOI

Full title: BIOLOGICAL AGE: METHODOLOGY FOR DETERMINING

Authors: A. Pisaruk; N. Koshel

Year: 2021

Venue: JOURNAL OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE

DOI: https://doi.org/10.37621/jnamsu-2021-3-1

Paper Data supplement for Fig 2.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for Fig 2.

Authors: (449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz; (22662731), Ayse Sena Mutlu; (10870897), Mary Piper; (10754436), Meeta Mistry; (3143652), Arpit Sharma; (22662734), Christopher S. Morrow; (3310815), Hannah Smith; (22662737), Porsha Howell; (17002225), Rohan Sehgal; (17002219), Anne Lanjuin; (256025), Meng C. Wang; (17002234), William B. Mair

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s019

Paper Data supplement for Fig 1.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for Fig 1.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s018

Paper Supplementary material.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Supplementary material.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s026

Paper Data supplement for S4, S5, and S6 Figs.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for S4, S5, and S6 Figs.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s024

Paper Data supplement for Fig 4.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for Fig 4.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s021

Paper Data supplement for Western Blot Full Gel Images.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for Western Blot Full Gel Images.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s025

Paper Data supplement for Fig 3.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for Fig 3.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s020

Paper Data supplement for S2 and S3 Figs.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for S2 and S3 Figs.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s023

Paper Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import

He, Chong; Tsuchiyama, Scott; Nguyen, Quynh Thi Thuy et al. · 2014 · PLoS Genetics · DOI

Full title: Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import

Authors: He, Chong; Tsuchiyama, Scott; Nguyen, Quynh Thi Thuy; Plyusnina, Ekaterina; Terrill, Samuel R.; Sahibzada, Sarah; Patel, Bhumil; Faulkner, Alena R.; Shaposhnikov, Mikhail; Tian, Ruilin; Tsuchiya, Mitsuhiro; Kaeberlein, Matt; Moskalev, Alexey; Kennedy, Brian K.; Polymenis, Michael

Year: 2014

Venue: PLoS Genetics

DOI: https://doi.org/10.1371/journal.pgen.1004860

Paper Data supplement for S1 Fig.

(449952), Sneha Dutta; (22662725), Maria Camila Perez Matos; (22662728), Caroline Heintz et al. · 2025 · Figshare · DOI

Full title: Data supplement for S1 Fig.

Year: 2025

Venue: Figshare

DOI: https://doi.org/10.1371/journal.pbio.3003504.s022

Paper A simplified design for the C. elegans lifespan machine.

Abbott, Mark; Banse, Stephen A; Melentijevic, Ilija et al. · 2020 · Journal of biological methods · DOI

Full title: A simplified design for the C. elegans lifespan machine.

Authors: Abbott, Mark; Banse, Stephen A; Melentijevic, Ilija; Jarrett, Cody M; Ange, Jonathan St; Sedore, Christine A; Falkowski, Ron; Blue, Benjamin W; Coleman-Hulbert, Anna L; Johnson, Erik; Guo, Max; Lithgow, Gordon J; Phillips, Patrick C; Driscoll, Monica

Year: 2020

Venue: Journal of biological methods

DOI: https://doi.org/10.14440/jbm.2020.332

Paper Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging.

Anisimov, Vladimir N; Zabezhinski, Mark A; Popovich, Irina G et al. · 2012 · Expert opinion on drug discovery · DOI

Full title: Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging.

Authors: Anisimov, Vladimir N; Zabezhinski, Mark A; Popovich, Irina G; Pliss, Gennady B; Bespalov, Vladimir G; Alexandrov, Valeri A; Stukov, Alexander N; Anikin, Ivan V; Alimova, Irina N; Egormin, Peter А; Panchenko, Andrey V; Piskunova, Tatiana S; Semenchenko, Anna V; Tyndyk, Margarita L; Yurova, Maria N

Year: 2012

Venue: Expert opinion on drug discovery

DOI: https://doi.org/10.1517/17460441.2012.642361

Paper Effects of Rhodiola rosea and aspirin on behaviour and some biochemical parameters in old mice

Vitalii Derkachov; Vladyslav Berezovskyi · 2024 · Journal of Vasyl Stefanyk Precarpathian National University. Biology · DOI

Full title: Effects of Rhodiola rosea and aspirin on behaviour and some biochemical parameters in old mice

Authors: Vitalii Derkachov; Vladyslav Berezovskyi

Year: 2024

Venue: Journal of Vasyl Stefanyk Precarpathian National University. Biology

DOI: https://doi.org/10.15330/jpnubio.11.93-103

Paper Spermidine protects cellular redox status and ionic homeostasis in D-galactose induced senescence and natural aging rat models.

Singh, Sandeep; Verma, Avnish Kumar; Garg, Geetika et al. · 2025 · Zeitschrift fur Naturforschung. C, Journal of biosciences · DOI

Full title: Spermidine protects cellular redox status and ionic homeostasis in D-galactose induced senescence and natural aging rat models.

Authors: Singh, Sandeep; Verma, Avnish Kumar; Garg, Geetika; Singh, Abhishek Kumar; Rizvi, Syed Ibrahim

Year: 2025

Venue: Zeitschrift fur Naturforschung. C, Journal of biosciences

DOI: https://doi.org/10.1515/znc-2024-0181

Paper Az élettartamot meghatározó exogén és endogén tényezők • Exogenous and Endogenous Factors Determining Lifespan

T. Halmos; I. Suba · 2023 · Magyar Tudomány · DOI

Full title: Az élettartamot meghatározó exogén és endogén tényezők • Exogenous and Endogenous Factors Determining Lifespan

Authors: T. Halmos; I. Suba

Year: 2023

Venue: Magyar Tudomány

DOI: https://doi.org/10.1556/2065.184.2023.7.7

Paper Relating aging and autophagy: a new perspective towards the welfare of human health.

Ghosh Chowdhury, Sougata; Ray, Rachayeeta; Karmakar, Parimal · 2023 · EXCLI journal · DOI

Full title: Relating aging and autophagy: a new perspective towards the welfare of human health.

Authors: Ghosh Chowdhury, Sougata; Ray, Rachayeeta; Karmakar, Parimal

Year: 2023

Venue: EXCLI journal

DOI: https://doi.org/10.17179/excli2023-6300

Paper Exploring the role of mTOR pathway in aging and age-related disorders.

Raghuvanshi, Komal; Raghuvanshi, Disha; Kumar, Dinesh et al. · 2025 · EXCLI journal · DOI

Full title: Exploring the role of mTOR pathway in aging and age-related disorders.

Authors: Raghuvanshi, Komal; Raghuvanshi, Disha; Kumar, Dinesh; Nepovimova, Eugenie; Valko, Marian; Kuca, Kamil; Verma, Rachna

Year: 2025

Venue: EXCLI journal

DOI: https://doi.org/10.17179/excli2025-8384

Paper Kidney Disease as a Driver of Immunosenescence: Mechanisms and Potential Interventions.

Song, Zhuolun; Tsou, Sarah; Martin, Friederike et al. · 2026 · Journal of the American Society of Nephrology : JASN · DOI

Full title: Kidney Disease as a Driver of Immunosenescence: Mechanisms and Potential Interventions.

Authors: Song, Zhuolun; Tsou, Sarah; Martin, Friederike; Kayumov, Mukhammad; Xiao, Yao; Zhou, Hao; Abdi, Reza; Tullius, Stefan G

Year: 2026

Venue: Journal of the American Society of Nephrology : JASN

DOI: https://doi.org/10.1681/ASN.0000000896

Paper Reviewer #2 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna L et al. · 2024 · DOI

Full title: Reviewer #2 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Authors: Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna L; Johnson, Erik; Onken, Brian; Hall, David; Segerdell, Erik; Jones, E Grace; Song, Yuhua; Osman, Hadley; Xue, Jian; Battistoni, Elena; Guo, Suzhen; Foulger, Anna C; Achanta, Madhuri; Sheikh, Mustafa; Fitzgibbon, Theresa; Willis, John H; Woodruff, Gavin C; Driscoll, Monica; Lithgow, Gordon J; Phillips, Patrick C

Year: 2024

DOI: https://doi.org/10.7554/elife.104375.1.sa1

Paper Reviewer #3 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna L et al. · 2024 · DOI

Full title: Reviewer #3 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Year: 2024

DOI: https://doi.org/10.7554/elife.104375.1.sa0

Paper Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes.

Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna et al. · 2025 · eLife · DOI

Full title: Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes.

Authors: Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna; Johnson, Erik; Onken, Brian; Hall, David; Segerdell, Erik; Jackson, E Grace; Song, Yuhua; Osman, Haley C; Xue, Jian; Basttistoni, Elena; Guo, Suhzen; Foulger, Anna; Achanta, Madhuri; Sheikh, Mustafa; Fitzgibbon, Theresa; Willis, John H; Woodruff, Gavin C; Driscoll, Monica; Lithgow, Gordon; Phillips, Patrick C

Year: 2025

Venue: eLife

DOI: https://doi.org/10.7554/eLife.104375

Paper eLife Assessment: Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Ghazi, Arjumand · 2024 · DOI

Full title: eLife Assessment: Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Authors: Ghazi, Arjumand

Year: 2024

DOI: https://doi.org/10.7554/elife.104375.1.sa3

Paper Reviewer #1 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Banse, Stephen A; Sedore, Christine A; Coleman-Hulbert, Anna L et al. · 2025 · DOI

Full title: Reviewer #1 (Public review): Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Year: 2025

DOI: https://doi.org/10.7554/elife.104375.2.sa3

Paper Regulation of Stress-Induced Longevity

Miller, Hillary · 2021 · Deep Blue (University of Michigan) · DOI

Full title: Regulation of Stress-Induced Longevity

Authors: Miller, Hillary

Year: 2021

Venue: Deep Blue (University of Michigan)

DOI: https://doi.org/10.7302/3001

Paper Author response: Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Banse, Stephen A.; Sedore, Christine A.; Coleman-Hulbert, Anna L et al. · 2025 · DOI

Full title: Author response: Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

Authors: Banse, Stephen A.; Sedore, Christine A.; Coleman-Hulbert, Anna L; Johnson, Erik; Onken, Brian; Hall, David; Segerdell, Erik; Jones, E Grace; Song, Yuhua; Osman, Hadley; Xue, Jian; Battistoni, Elena; Guo, Suzhen; Foulger, Anna; Achanta, Madhuri; Sheikh, Mustafa; Fitzgibbon, Theresa; Willis, John H.; Woodruff, Gavin C.; Driscoll, Monica; Lithgow, Gordon J.; Phillips, Patrick C.

Year: 2025

DOI: https://doi.org/10.7554/elife.104375.2.sa0

Paper Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice.

Fielder, Edward; Wan, Tengfei; Alimohammadiha, Ghazaleh et al. · 2022 · eLife · DOI

Full title: Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice.

Authors: Fielder, Edward; Wan, Tengfei; Alimohammadiha, Ghazaleh; Ishaq, Abbas; Low, Evon; Weigand, B Melanie; Kelly, George; Parker, Craig; Griffin, Brigid; Jurk, Diana; Korolchuk, Viktor I; von Zglinicki, Thomas; Miwa, Satomi

Year: 2022

Venue: eLife

DOI: https://doi.org/10.7554/eLife.75492

Paper Author response: Epigenetic age-predictor for mice based on three CpG sites

Han, Yang; Eipel, Monika; Franzen, Julia et al. · 2018 · DOI

Full title: Author response: Epigenetic age-predictor for mice based on three CpG sites

Authors: Han, Yang; Eipel, Monika; Franzen, Julia; Sakk, Vadim; Dethmers-Ausema, Bertien; Yndriago, Laura; Izeta, Ander; Haan, Gerald de; Geiger, Hartmut; Wagner, Wolfgang

Year: 2018

DOI: https://doi.org/10.7554/elife.37462.015

Paper Reviewer #2 (Public Review): Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

· 2024 · DOI

Full title: Reviewer #2 (Public Review): Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Year: 2024

DOI: https://doi.org/10.7554/elife.90579.3.sa2

Paper A scalable and tunable platform for functional interrogation of peptide hormones in fish.

Moses, Eitan; Franek, Roman; Harel, Itamar · 2023 · eLife · DOI

Full title: A scalable and tunable platform for functional interrogation of peptide hormones in fish.

Authors: Moses, Eitan; Franek, Roman; Harel, Itamar

Year: 2023

Venue: eLife

DOI: https://doi.org/10.7554/eLife.85960

Paper eLife assessment: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Benayoun, Bérénice A. · 2024 · DOI

Full title: eLife assessment: Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Authors: Benayoun, Bérénice A.

Year: 2024

DOI: https://doi.org/10.7554/elife.90579.3.sa0

Paper AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Alexandru, Plesa, · 2022 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING

Authors: Alexandru, Plesa,

Year: 2022

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper Anti-aging Interventions: Caloric Restriction and Beyond

K. S. Ong; Zack St. Lim; B. Setiawan · 2018 · Cermin Dunia Kedokteran

Full title: Anti-aging Interventions: Caloric Restriction and Beyond

Authors: K. S. Ong; Zack St. Lim; B. Setiawan

Year: 2018

Venue: Cermin Dunia Kedokteran

Paper Ancient metabolic switches underpinning organismal longevity

Mubtasim, Ahsan, Fasih · 2025 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Full title: Ancient metabolic switches underpinning organismal longevity

Authors: Mubtasim, Ahsan, Fasih

Year: 2025

Venue: Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Paper [Aging and carcinogenesis].

Anisimov, V N · 2002 · Advances in gerontology = Uspekhi gerontologii

Full title: [Aging and carcinogenesis].

Authors: Anisimov, V N

Year: 2002

Venue: Advances in gerontology = Uspekhi gerontologii

Paper An Exploration of the Genetics and Molecular Mechanisms Underlying Conserved Longevity Interventions

G. Sutphin · 2012 · ResearchWorks at the University of Washington (University of Washington)

Full title: An Exploration of the Genetics and Molecular Mechanisms Underlying Conserved Longevity Interventions

Authors: G. Sutphin

Year: 2012

Venue: ResearchWorks at the University of Washington (University of Washington)

Paper [Attitudes toward aging prevention: results of a focus groups study].

Smol'kin, A A; Zhigareva, P A; Makarova, E A et al. · 2017 · Advances in gerontology = Uspekhi gerontologii

Full title: [Attitudes toward aging prevention: results of a focus groups study].

Authors: Smol'kin, A A; Zhigareva, P A; Makarova, E A; Kiryukhina, A A; Milova, E A; Khaltourina, D A

Year: 2017

Venue: Advances in gerontology = Uspekhi gerontologii

Paper A validated mouse frailty index to assess longevity interventions: Impact of species, calorie restriction and resveratrol.

A. Kane; S. Hilmer; D. Boyer et al. · 2015 · Research Explorer (The University of Manchester)

Full title: A validated mouse frailty index to assess longevity interventions: Impact of species, calorie restriction and resveratrol.

Authors: A. Kane; S. Hilmer; D. Boyer; K. Gavin; Dawn Nines; S. Howlett; Cabo R de; S. Mitchell

Year: 2015

Venue: Research Explorer (The University of Manchester)

Paper Curcumin-induced hormetic effects in human skin fibroblasts : implications toward anti-ageing interventions

Lima, Cristóvão F.; Pereira‐Wilson, Cristina; Rattan, Suresh I. S. · 2011 · RepositóriUM (Universidade do Minho)

Full title: Curcumin-induced hormetic effects in human skin fibroblasts : implications toward anti-ageing interventions

Authors: Lima, Cristóvão F.; Pereira‐Wilson, Cristina; Rattan, Suresh I. S.

Year: 2011

Venue: RepositóriUM (Universidade do Minho)

Paper Effects of antioxidant supplementation on the aging process

D. Fusco; G. Colloca; Maria Rita Lo Monaco et al. · 2007 · Clinical Interventions in Aging

Full title: Effects of antioxidant supplementation on the aging process

Authors: D. Fusco; G. Colloca; Maria Rita Lo Monaco; M. Cesari

Year: 2007

Venue: Clinical Interventions in Aging

Paper Effects of low level and severe dietary restriction on age-related sarcopenia

G. Cavallini; S. Straniero; A. Donati et al. · 2008 · CINECA IRIS Institutial research information system (University of Pisa)

Full title: Effects of low level and severe dietary restriction on age-related sarcopenia

Authors: G. Cavallini; S. Straniero; A. Donati; E. Bergamini

Year: 2008

Venue: CINECA IRIS Institutial research information system (University of Pisa)

Paper The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience - Through the lens of the "900-day rule".

Pabis, Kamil; Barardo, Diogo; Gruber, Jan et al. · 2024 · Ageing research reviews · DOI

Full title: The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience - Through the lens of the "900-day rule".

Authors: Pabis, Kamil; Barardo, Diogo; Gruber, Jan; Sirbu, Olga; Malavolta, Marco; Selvarajoo, Kumar; Kaeberlein, Matt; Kennedy, Brian K

Year: 2024

Venue: Ageing research reviews

DOI: https://doi.org/10.1016/j.arr.2024.102512

Paper Uncertainty quantification in epigenetic clocks via conformalized quantile regression.

Li, Yanping; Goodrich, Jaclyn M; Peterson, Karen E et al. · 2025 · medRxiv : the preprint server for health sciences · DOI

Full title: Uncertainty quantification in epigenetic clocks via conformalized quantile regression.

Authors: Li, Yanping; Goodrich, Jaclyn M; Peterson, Karen E; Song, Peter X-K; Luo, Lan

Year: 2025

Venue: medRxiv : the preprint server for health sciences

DOI: https://doi.org/10.1101/2024.09.06.24313192

Paper Molecular signatures of longevity identify compounds that extend mouse lifespan and healthspan

A. Shindyapina; A. Tyshkovskiy; Perinur Bozaykut et al. · 2025 · bioRxiv · DOI

Full title: Molecular signatures of longevity identify compounds that extend mouse lifespan and healthspan

Authors: A. Shindyapina; A. Tyshkovskiy; Perinur Bozaykut; J. P. Castro; Maxim V. Gerashchenko; Alexandre Trapp; Margarita Meer; Bohan Zhang; J. Poganik; S. Horvath; Richard A. Miller; V. Gladyshev

Year: 2025

Venue: bioRxiv

DOI: https://doi.org/10.1101/2025.06.26.661776

Paper Yeast replicative aging: a paradigm for defining conserved longevity interventions.

Wasko, Brian M; Kaeberlein, Matt · 2014 · FEMS yeast research · DOI

Full title: Yeast replicative aging: a paradigm for defining conserved longevity interventions.

Authors: Wasko, Brian M; Kaeberlein, Matt

Year: 2014

Venue: FEMS yeast research

DOI: https://doi.org/10.1111/1567-1364.12104

Paper Interventions to Slow Aging in Humans: Are We Ready?

Longo, Valter D.; Antebi, Adam; Bartke, Andrzej et al. · 2015 · Aging Cell · DOI

Full title: Interventions to Slow Aging in Humans: Are We Ready?

Authors: Longo, Valter D.; Antebi, Adam; Bartke, Andrzej; Barzilai, Nir; Brown‐Borg, Holly M.; Caruso, Calogero; Curiel, Tyler J.; Cabo, Rafael de; Franceschi, Claudio; Gems, David; Ingram, Donald K.; Johnson, Thomas E.; Kennedy, Brian K.; Kenyon, Cynthia; Klein, Samuel; Kopchick, John J.; Lepperdinger, Günter; Madeo, Frank; Mirisola, Mario G.; Mitchell, James R.; Passarino, Giuseppe; Rudolph, K. Lenhard; Sedivy, John M.; Shadel, Gerald S.; Sinclair, David; Spindler, Stephen R.; Suh, Yousin; Vijg, Jan; Vinciguerra, Manlio; Fontana, Luigi

Year: 2015

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12338

Paper A Pan-Tissue Epigenetic Aging Clock Across the Human Lifespan: Robust Age Prediction from DNA Methylation Profiles

Zhejun Kuang; Kangwei Geng; Jian Zhao et al. · 2025 · IEEE International Conference on Bioinformatics and Biomedicine · DOI

Full title: A Pan-Tissue Epigenetic Aging Clock Across the Human Lifespan: Robust Age Prediction from DNA Methylation Profiles

Authors: Zhejun Kuang; Kangwei Geng; Jian Zhao; L. Shi; Han Wang; Han-geng Sun

Year: 2025

Venue: IEEE International Conference on Bioinformatics and Biomedicine

DOI: https://doi.org/10.1109/bibm66473.2025.11356186

Paper Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Miller, Richard A.; Harrison, David E.; Astle, Clinton M. et al. · 2013 · Aging Cell · DOI

Full title: Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Authors: Miller, Richard A.; Harrison, David E.; Astle, Clinton M.; Fernández, Elizabeth; Flurkey, Kevin; Han, Melissa; Javors, Martin A.; Li, Xinna; Nadon, Nancy L.; Nelson, James F.; Pletcher, Scott D.; Salmon, Adam B.; Sharp, Z. Dave; Roekel, Sabrina Van; Winkleman, Lynn; Strong, Randy

Year: 2013

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12194

Paper Age‐specific mortality and fecundity of a spider mite under diet restriction and delayed mating

Guang-Yun Li; Zhi-qiang Zhang · 2021 · Insect Science · DOI

Full title: Age‐specific mortality and fecundity of a spider mite under diet restriction and delayed mating

Authors: Guang-Yun Li; Zhi-qiang Zhang

Year: 2021

Venue: Insect Science

DOI: https://doi.org/10.1111/1744-7917.12948

Paper Sex differences in lifespan extension with acarbose and 17‐α estradiol: gonadal hormones underlie male‐specific improvements in glucose tolerance and mTORC 2 signaling

Garratt, Michael; Bower, Brian D.; Garcia, Gonzalo G. et al. · 2017 · Aging Cell · DOI

Full title: Sex differences in lifespan extension with acarbose and 17‐α estradiol: gonadal hormones underlie male‐specific improvements in glucose tolerance and mTORC 2 signaling

Authors: Garratt, Michael; Bower, Brian D.; Garcia, Gonzalo G.; Miller, Richard A.

Year: 2017

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12656

Paper Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

Martin, Stephen A.; DeMuth, Tyler M.; Miller, Karl N. et al. · 2015 · Aging Cell · DOI

Full title: Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

Authors: Martin, Stephen A.; DeMuth, Tyler M.; Miller, Karl N.; Pugh, Thomas D.; Polewski, Michael A.; Colman, Ricki J.; Eliceiri, Kevin W.; Beasley, T. Mark; Johnson, Sterling C.; Anderson, Rozalyn M.

Year: 2015

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12418

Paper Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.

Lamming, Dudley W; Ye, Lan; Astle, Clinton M et al. · 2013 · Aging cell · DOI

Full title: Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.

Authors: Lamming, Dudley W; Ye, Lan; Astle, Clinton M; Baur, Joseph A; Sabatini, David M; Harrison, David E

Year: 2013

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12097

Paper Dietary restriction involves NAD +‐dependent mechanisms and a shift toward oxidative metabolism

Moroz, Natalie; Carmona, Juan J.; Anderson, Edward et al. · 2014 · Aging Cell · DOI

Full title: Dietary restriction involves NAD +‐dependent mechanisms and a shift toward oxidative metabolism

Authors: Moroz, Natalie; Carmona, Juan J.; Anderson, Edward; Hart, Anne C.; Sinclair, David; Blackwell, T. Keith

Year: 2014

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12273

Paper Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox

Yang, Liang; Lin, Xiaobing; Tang, Haite et al. · 2020 · Aging Cell · DOI

Full title: Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox

Authors: Yang, Liang; Lin, Xiaobing; Tang, Haite; Fan, Yuting; Zeng, Sheng; Jia, Lei; Li, Yukun; Shi, Yanan; He, Shujing; Wang, Hao; Hu, Zhijuan; Gong, Xiao; Liang, Xiaoyan; Yang, Yi; Liu, Xingguo

Year: 2020

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13206

Paper Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells.

Ogrodnik, Mikolaj; Salmonowicz, Hanna; Gladyshev, Vadim N · 2019 · Aging cell · DOI

Full title: Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells.

Authors: Ogrodnik, Mikolaj; Salmonowicz, Hanna; Gladyshev, Vadim N

Year: 2019

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12841

Paper Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic.

Moskalev, Alexey; Chernyagina, Elizaveta; Tsvetkov, Vasily et al. · 2016 · Aging cell · DOI

Full title: Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic.

Authors: Moskalev, Alexey; Chernyagina, Elizaveta; Tsvetkov, Vasily; Fedintsev, Alexander; Shaposhnikov, Mikhail; Krut'ko, Vyacheslav; Zhavoronkov, Alex; Kennedy, Brian K

Year: 2016

Venue: Aging cell

DOI: https://doi.org/10.1111/acel.12463

Paper Functional microbiome deficits associated with ageing: Chronological age threshold

Ruiz‐Ruiz, Susana; Sánchez-Carrillo, Sergio; Ciordia, Sergio et al. · 2019 · Aging Cell · DOI

Full title: Functional microbiome deficits associated with ageing: Chronological age threshold

Authors: Ruiz‐Ruiz, Susana; Sánchez-Carrillo, Sergio; Ciordia, Sergio; Mena, María Carmen; Méndez–García, Celia; Rojo, David; Bargiela, Rafael; Zubeldia‐Varela, Elisa; Martínez‐Martínez, Mónica; Barbas, Coral; Ferrer, Manuel; Moyá, Andrés

Year: 2019

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13063

Paper Mitochondrial‐targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?

Basisty, Nathan; Dai, Dao‐Fu; Gagnidze, Arni et al. · 2016 · Aging Cell · DOI

Full title: Mitochondrial‐targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?

Authors: Basisty, Nathan; Dai, Dao‐Fu; Gagnidze, Arni; Gitari, Lemuel; Fredrickson, Jeanne; Maina, Yvonne; Beyer, Richard P.; Emond, Mary J.; Hsieh, Edward J.; MacCoss, Michael J.; Martin, George M.; Rabinovitch, Peter S.

Year: 2016

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12472

Paper Overexpression of CYB 5R3 and NQO 1, two NAD +‐producing enzymes, mimics aspects of caloric restriction

Díaz‐Ruiz, Alberto; Lanasa, Michael; Garcia, Joseph et al. · 2018 · Aging Cell · DOI

Full title: Overexpression of CYB 5R3 and NQO 1, two NAD +‐producing enzymes, mimics aspects of caloric restriction

Authors: Díaz‐Ruiz, Alberto; Lanasa, Michael; Garcia, Joseph; Mora, Hector; Fan, Frances; Martín‐Montalvo, Alejandro; Francesco, Andrea Di; Calvo‐Rubio, Miguel; Salvador‐Pascual, Andrea; Aon, Miguel A.; Fishbein, Kenneth W.; Pearson, Kevin J.; Villalba, José M.; Navas, Plácido; Bernier, Michel; Cabo, Rafael de

Year: 2018

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12767

Paper Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Strong, Randy; Strong, Randy; Allison, David B. et al. · 2013 · Aging Cell · DOI

Full title: Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Authors: Strong, Randy; Strong, Randy; Allison, David B.; Ames, Bruce N.; Astle, Clinton M.; Atamna, Hani; Fernández, Elizabeth; Flurkey, Kevin; Javors, Martin A.; Nadon, Nancy L.; Nelson, James F.; Pletcher, Scott D.; Simpkins, James W.; Smith, Daniel L.; Wilkinson, John E.; Miller, Richard A.

Year: 2013

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.12170

Paper The effect of a pharmaceutical ghrelin agonist on lifespan in C57BL / 6J male mice: A controlled experiment

Kaiser, Kathryn A.; Kadish, Inga; Groen, Thomas van et al. · 2023 · Aging Cell · DOI

Full title: The effect of a pharmaceutical ghrelin agonist on lifespan in C57BL / 6J male mice: A controlled experiment

Authors: Kaiser, Kathryn A.; Kadish, Inga; Groen, Thomas van; Smith, Daniel L.; Dickinson, Stephanie; Henschel, Beate; Parker, Erik; Brown, Andrew W.; Allison, David B.

Year: 2023

Venue: Aging Cell

DOI: https://doi.org/10.1111/acel.13787

Paper Immunosenescence is a therapeutic target for frailty in older adults: a narrative review

Jia, Huanan; Huang, Wei; Liu, Chuanfeng et al. · 2022 · Annals of Translational Medicine · DOI

Full title: Immunosenescence is a therapeutic target for frailty in older adults: a narrative review

Authors: Jia, Huanan; Huang, Wei; Liu, Chuanfeng; Tang, Shiyu; Zhang, Jing; Chen, Chongli; Tian, Yuan; Zhong, Wen

Year: 2022

Venue: Annals of Translational Medicine

DOI: https://doi.org/10.21037/atm-22-4405

Paper Endocrine Regulation of Aging in the Fruit Fly Drosophila melanogaster

Qian, Qingyin; Niwa, Ryusuke · 2023 · ZOOLOGICAL SCIENCE · DOI

Full title: Endocrine Regulation of Aging in the Fruit Fly Drosophila melanogaster

Authors: Qian, Qingyin; Niwa, Ryusuke

Year: 2023

Venue: ZOOLOGICAL SCIENCE

DOI: https://doi.org/10.2108/zs230056

Paper PICLS with human cells - first high-throughput screening method with human assay identifies novel longevity compounds including 2,5-anhydro-D-mannitol that increase chronological lifespan

Alfatah, Mohammad; Zhang, Yizhong; Cheng, Trishia Yi Ning et al. · 2023 · Research Square (Research Square) · DOI

Full title: PICLS with human cells - first high-throughput screening method with human assay identifies novel longevity compounds including 2,5-anhydro-D-mannitol that increase chronological lifespan

Authors: Alfatah, Mohammad; Zhang, Yizhong; Cheng, Trishia Yi Ning; Naaz, Arshia; Eisenhaber, Frank

Year: 2023

Venue: Research Square (Research Square)

DOI: https://doi.org/10.21203/rs.3.rs-2833704/v1

Paper In vivo medical imaging for assessing geroprotective interventions in humans

Svensson, Jonas E.; Schain, Martin; Sigray, Pontus Plavén · 2024 · DOI

Full title: In vivo medical imaging for assessing geroprotective interventions in humans

Authors: Svensson, Jonas E.; Schain, Martin; Sigray, Pontus Plavén

Year: 2024

DOI: https://doi.org/10.21203/rs.3.rs-4095045/v1

Paper Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

Andrea Di Francesco; Andrew Deighan; L. Litichevskiy et al. · 2023 · bioRxiv · DOI

Full title: Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

Year: 2023

Venue: bioRxiv

DOI: https://doi.org/10.1101/2023.11.28.568901

Paper Longevity Interventions Temporally Scale Healthspan in Caenorhabditis elegans

Statzer, Cyril; Reichert, Peter; Dual, Jürg et al. · 2021 · SSRN Electronic Journal · DOI

Full title: Longevity Interventions Temporally Scale Healthspan in Caenorhabditis elegans

Authors: Statzer, Cyril; Reichert, Peter; Dual, Jürg; Ewald, Collin Y.

Year: 2021

Venue: SSRN Electronic Journal

DOI: https://doi.org/10.2139/ssrn.3894609

Paper An epigenetic clock for chronological age estimation in East Asian populations

Lu, Kuan‐Hung; Kuo, Po‐Hsiu; Chattopadhyay, Amrita et al. · 2025 · DOI

Full title: An epigenetic clock for chronological age estimation in East Asian populations

Authors: Lu, Kuan‐Hung; Kuo, Po‐Hsiu; Chattopadhyay, Amrita; Lu, Tzu‐Pin

Year: 2025

DOI: https://doi.org/10.21203/rs.3.rs-7327305/v1

Paper Bioactive Anti-Aging Substances: Geroprotectors

Anna Fokina; A. Vesnina; A. Frolova et al. · 2024 · Food processing · DOI

Full title: Bioactive Anti-Aging Substances: Geroprotectors

Authors: Anna Fokina; A. Vesnina; A. Frolova; Darya Chekushkina; L. Proskuryakova; Larisa Aksenova

Year: 2024

Venue: Food processing

DOI: https://doi.org/10.21603/2074-9414-2024-2-2517

Paper Cellular Senescence and Senolytic Agents: Recent Updates on Their Role and Applications.

Chandrakar, Lokesh; Ambatwar, Ramesh; Khatik, Gopal L · 2024 · Current topics in medicinal chemistry · DOI

Full title: Cellular Senescence and Senolytic Agents: Recent Updates on Their Role and Applications.

Authors: Chandrakar, Lokesh; Ambatwar, Ramesh; Khatik, Gopal L

Year: 2024

Venue: Current topics in medicinal chemistry

DOI: https://doi.org/10.2174/0115680266273698231107110956

Paper Is programmed aging a cause for optimism?

Mitteldorf, Josh · 2015 · Current aging science · DOI

Full title: Is programmed aging a cause for optimism?

Authors: Mitteldorf, Josh

Year: 2015

Venue: Current aging science

DOI: https://doi.org/10.2174/1874609808666150422112826

Paper Aging and senotherapeutics

I. Čepelak; S. Dodig · 2019 · Rad Hrvatske akademije znanosti i umjetnosti Medicinske znanosti · DOI

Full title: Aging and senotherapeutics

Authors: I. Čepelak; S. Dodig

Year: 2019

Venue: Rad Hrvatske akademije znanosti i umjetnosti Medicinske znanosti

DOI: https://doi.org/10.21857/moxpjhglzm

Paper Natural Products as a Major Source of Candidates for Potential Senolytic Compounds obtained by in silico Screening.

Barrera-Vázquez, Oscar S; Magos-Guerrero, Gil A; Escobar-Ramírez, Juan L et al. · 2023 · Medicinal chemistry (Shariqah (United Arab Emirates)) · DOI

Full title: Natural Products as a Major Source of Candidates for Potential Senolytic Compounds obtained by in silico Screening.

Authors: Barrera-Vázquez, Oscar S; Magos-Guerrero, Gil A; Escobar-Ramírez, Juan L; Gomez-Verjan, Juan C

Year: 2023

Venue: Medicinal chemistry (Shariqah (United Arab Emirates))

DOI: https://doi.org/10.2174/1573406419666221019153537

Paper Towards an understanding of the anti-aging mechanism of caloric restriction.

G. Cavallini; A. Donati; Z. Gori et al. · 2008 · Current Aging Science · DOI

Full title: Towards an understanding of the anti-aging mechanism of caloric restriction.

Authors: G. Cavallini; A. Donati; Z. Gori; E. Bergamini

Year: 2008

Venue: Current Aging Science

DOI: https://doi.org/10.2174/1874609810801010004

Paper Premature ageing prevention: limitations and perspectives of pharmacological interventions.

Anisimov, Vladimir N · 2006 · Current drug targets · DOI

Full title: Premature ageing prevention: limitations and perspectives of pharmacological interventions.

Authors: Anisimov, Vladimir N

Year: 2006

Venue: Current drug targets

DOI: https://doi.org/10.2174/1389450110607011485

Paper DIY Intervention Testing in Daphnia

Anderson, Cora E.; Jonas-Closs, Rachael A; Matei-Dediu, Benyamin et al. · 2023 · BIO-PROTOCOL · DOI

Full title: DIY Intervention Testing in Daphnia

Authors: Anderson, Cora E.; Jonas-Closs, Rachael A; Matei-Dediu, Benyamin; Debonneuil, Édouard; Peshkin, Leonid

Year: 2023

Venue: BIO-PROTOCOL

DOI: https://doi.org/10.21769/p2542

Paper Hormesis is applicable as a pro-healthy aging intervention in mammals and human beings.

Pardon, Marie-Christine · 2009 · Dose-response : a publication of International Hormesis Society · DOI

Full title: Hormesis is applicable as a pro-healthy aging intervention in mammals and human beings.

Authors: Pardon, Marie-Christine

Year: 2009

Venue: Dose-response : a publication of International Hormesis Society

DOI: https://doi.org/10.2203/dose-response.09-020.Pardon

Paper An Obscure Natural NAD + -Boosting Sirtuin Activator: N 1 -Methylnicotinamide (1-MNA)

Alpay, Faruk · 2025 · DOI

Full title: An Obscure Natural NAD + -Boosting Sirtuin Activator: N 1 -Methylnicotinamide (1-MNA)

Authors: Alpay, Faruk

Year: 2025

DOI: https://doi.org/10.22541/au.175312720.01281720/v1

Paper Feasibility of an Embedded Voice-Based AI Health Monitoring Within a Group-Based Longevity Program for Older Adults (Preprint)

Endo, Kumiko; Khanh, Ha Huynh Mai; Ikehata, Yoshihiro et al. · 2026 · DOI

Full title: Feasibility of an Embedded Voice-Based AI Health Monitoring Within a Group-Based Longevity Program for Older Adults (Preprint)

Authors: Endo, Kumiko; Khanh, Ha Huynh Mai; Ikehata, Yoshihiro; Jeong, Sohyeong; Komazawa, Makoto; Kwak, Boeun; Velilla, Regine Paola; Paeng, Hansol; Truong, Bao C. Q.; Horie, Shigeo

Year: 2026

DOI: https://doi.org/10.2196/preprints.92827

Paper Relevance of Bioassay of Biologically Active Substances (BAS) with Geroprotective Properties in the Model of the Nematode Caenorhabditis Elegans in In Vivo Experiments.

Dyshlyuk, Lyubov S; Dmitrieva, Anastasiya I; Drozdova, Margarita Yu et al. · 2022 · Current aging science · DOI

Full title: Relevance of Bioassay of Biologically Active Substances (BAS) with Geroprotective Properties in the Model of the Nematode Caenorhabditis Elegans in In Vivo Experiments.

Authors: Dyshlyuk, Lyubov S; Dmitrieva, Anastasiya I; Drozdova, Margarita Yu; Milentyeva, Irina S; Prosekov, Alexander Yu

Year: 2022

Venue: Current aging science

DOI: https://doi.org/10.2174/1874609814666211202144911

Paper Aging delay: of mice and men.

Anisimov, Vladimir · 2021 · Acta bio-medica : Atenei Parmensis · DOI

Full title: Aging delay: of mice and men.

Authors: Anisimov, Vladimir

Year: 2021

Venue: Acta bio-medica : Atenei Parmensis

DOI: https://doi.org/10.23750/abm.v92i1.11273

Paper Boosting NAD+ for Anti-Aging: Mechanisms, Interventions, and Opportunities

Alpay, Faruk · 2025 · DOI

Full title: Boosting NAD+ for Anti-Aging: Mechanisms, Interventions, and Opportunities

Authors: Alpay, Faruk

Year: 2025

DOI: https://doi.org/10.26434/chemrxiv-2025-nl80r

Paper Artificial intelligence-assisted identification and validation of anti-aging biomarkers

Zikuan Bai · 2024 · Academic Journal of Medicine & Health Sciences · DOI

Full title: Artificial intelligence-assisted identification and validation of anti-aging biomarkers

Authors: Zikuan Bai

Year: 2024

Venue: Academic Journal of Medicine & Health Sciences

DOI: https://doi.org/10.25236/ajmhs.2024.051207

Paper From genoprotection to rejuvenation.

Tabibzadeh, Siamak · 2021 · Frontiers in bioscience (Landmark edition) · DOI

Full title: From genoprotection to rejuvenation.

Authors: Tabibzadeh, Siamak

Year: 2021

Venue: Frontiers in bioscience (Landmark edition)

DOI: https://doi.org/10.2741/4890

Paper Testing of geroprotectors in experiments on cell cultures: Choosing the correct model system

A. Khokhlov; A. A. Klebanov; A. F. Karmushakov et al. · 2014 · Moscow University Biological Sciences Bulletin · DOI

Full title: Testing of geroprotectors in experiments on cell cultures: Choosing the correct model system

Authors: A. Khokhlov; A. A. Klebanov; A. F. Karmushakov; G. Shilovsky; M. M. Nasonov; G. Morgunova

Year: 2014

Venue: Moscow University Biological Sciences Bulletin

DOI: https://doi.org/10.3103/s0096392514020035

Paper Metformina farmaco anti-aging? Tra promesse ed evidenze

Vittoria Cataldo; G. Paolisso · 2022 · il Diabete · DOI

Full title: Metformina farmaco anti-aging? Tra promesse ed evidenze

Authors: Vittoria Cataldo; G. Paolisso

Year: 2022

Venue: il Diabete

DOI: https://doi.org/10.30682/ildia2202d

Paper The regeneration model of aging and its practical implications

Erik Dassoff · 2026 · Discover medicine · DOI

Full title: The regeneration model of aging and its practical implications

Authors: Erik Dassoff

Year: 2026

Venue: Discover medicine

DOI: https://doi.org/10.1007/s44337-025-00558-5

Paper Slowing aging across all ages: from theory to practice

Dassoff, Erik Scott · 2024 · DOI

Full title: Slowing aging across all ages: from theory to practice

Authors: Dassoff, Erik Scott

Year: 2024

DOI: https://doi.org/10.31219/osf.io/e8kzr

Paper Slowing aging across all ages: from theory to practice

Dassoff, Erik Scott · 2024 · DOI

Full title: Slowing aging across all ages: from theory to practice

Authors: Dassoff, Erik Scott

Year: 2024

DOI: https://doi.org/10.31219/osf.io/e8kzr

Paper Influence of Metabolic Interventions on Animal Aging and Lifespan

Ghosh, Bhaswati; Ghosh, Bhaswati · 2023 · DOI

Full title: Influence of Metabolic Interventions on Animal Aging and Lifespan

Authors: Ghosh, Bhaswati; Ghosh, Bhaswati

Year: 2023

DOI: https://doi.org/10.31390/gradschool_dissertations.6092

Paper A Need for Refined Senescence Biomarkers and Measures of Senolytics in the Brain.

Orr, Miranda E · 2024 · Journal of Alzheimer's disease : JAD · DOI

Full title: A Need for Refined Senescence Biomarkers and Measures of Senolytics in the Brain.

Authors: Orr, Miranda E

Year: 2024

Venue: Journal of Alzheimer's disease : JAD

DOI: https://doi.org/10.3233/JAD-231462

Paper The Brain-body Energy Conservation Model of Aging

Shaulson, Evan D.; Cohen, Alan A.; Picard, Martin · 2023 · DOI

Full title: The Brain-body Energy Conservation Model of Aging

Authors: Shaulson, Evan D.; Cohen, Alan A.; Picard, Martin

Year: 2023

DOI: https://doi.org/10.31219/osf.io/zuey2

Paper Aging management — a new strategy for cardiovascular risk prevention

I.M. Khapokhov; A. S. Ryazanov; Z.A. Nabieva et al. · 2024 · Therapist's Bulletin · DOI

Full title: Aging management — a new strategy for cardiovascular risk prevention

Authors: I.M. Khapokhov; A. S. Ryazanov; Z.A. Nabieva; M. V. Makarovskaya

Year: 2024

Venue: Therapist's Bulletin

DOI: https://doi.org/10.31550/2712-8601-vt-2024-4-1

Paper Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease.

Garbarino, Valentina R; Palavicini, Juan Pablo; Melendez, Justin et al. · 2025 · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · DOI

Full title: Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease.

Authors: Garbarino, Valentina R; Palavicini, Juan Pablo; Melendez, Justin; Barthelemy, Nicolas R; He, Yingxin; Kautz, Tiffany F; Lopez-Cruzan, Marisa; Mathews, Julia J; Xu, Peng; Zhang, Bin; Saliba, Afaf; Ragi, Nagarjunachary; Sharma, Kumar; Mason, Dallin; Johnson, Samuel; Hendrix, Suzanne; Craft, Suzanne; Petersen, Ronald C; Espindola-Netto, Jair Machado; Xue, Ailing; Tchkonia, Tamara; Kirkland, James L; Salardini, Arash; Musi, Nicolas; Bateman, Randall J; Gonzales, Mitzi M; Orr, Miranda E

Year: 2025

Venue: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

DOI: https://doi.org/10.1016/j.neurot.2025.e00591

Thesis Effects of intermittent fasting on cognitive health and Alzheimer's disease

Elias, A; Padinjakara, N; Lautenschlager, NT · 2023 · University of Melbourne · DOI

Full title: Effects of intermittent fasting on cognitive health and Alzheimer's disease

Authors: Elias, A; Padinjakara, N; Lautenschlager, NT

Year: 2023

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/337314

Thesis Towards personalized nicotinamide mononucleotide (NMN) supplementation: Nicotinamide adenine dinucleotide (NAD) concentration

Kuerec, AH; Wang, W; Yi, L et al. · 2024 · University of Melbourne · DOI

Full title: Towards personalized nicotinamide mononucleotide (NMN) supplementation: Nicotinamide adenine dinucleotide (NAD) concentration

Authors: Kuerec, AH; Wang, W; Yi, L; Tao, R; Lin, Z; Vaidya, A; Pendse, S; Thasma, S; Andhalkar, N; Avhad, G; Kumbhar, V; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/348515

Thesis Meeting Report: Aging Research and Drug Discovery

Meron, E; Thaysen, M; Angeli, S et al. · 2022 · University of Melbourne · DOI

Full title: Meeting Report: Aging Research and Drug Discovery

Authors: Meron, E; Thaysen, M; Angeli, S; Antebi, A; Barzilai, N; Baur, JA; Bekker-Jensen, S; Birkisdottir, M; Bischof, E; Bruening, J; Brunet, A; Buchwalter, A; Cabreiro, F; Cai, S; Chen, BH; Ermolaeva, M; Ewald, CY; Ferrucci, L; Florian, MC; Fortney, K; Freund, A; Georgievskaya, A; Gladyshev, VN; Glass, D; Golato, T; Gorbunova, V; Hoejimakers, J; Houtkooper, RH; Jager, S; Jaksch, F; Janssens, G; Jensen, MB; Kaeberlein, M; Karsenty, G; de Keizer, P; Kennedy, B; Kirkland, JL; Kjaer, M; Kroemer, G; Lee, KF; Lemaitre, JM; Liaskos, D; Longo, VD; Lu, YX; MacArthur, MR; Maier, AB; Manakanatas, C; Mitchell, SJ; Moskalev, A; Niedernhofer, L; Ozerov, I; Partridge, L; Passegué, E; Petr, MA; Peyer, J; Radenkovic, D; Rando, TA; Rattan, S; Riedel, CG; Rudolph, L; Ai, R; Serrano, M; Schumacher, B; Sinclair, DA; Smith, R; Suh, Y; Taub, P; Trapp, A; Trendelenburg, AU; Valenzano, DR; Verburgh, K; Verdin, E; Vijg, J; Westendorp, RGJ; Zonari, A; Bakula, D; Zhavoronkov, A; Scheibye-Knudsen, M

Year: 2022

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/301482

Thesis Diet-induced phenotypic plasticity during aging

Rusli, Fenni · 2016 · Wageningen University & Research · DOI

Full title: Diet-induced phenotypic plasticity during aging

Authors: Rusli, Fenni

Year: 2016

Venue: Wageningen University & Research

DOI: https://research.wur.nl/en/publications/diet-induced-phenotypic-plasticity-during-aging

Thesis Therapeutic effect of dietary ingredients on cellular senescence in animals and humans: A systematic review

Guan, L; Eisenmenger, A; Crasta, KC et al. · 2024 · University of Melbourne · DOI

Full title: Therapeutic effect of dietary ingredients on cellular senescence in animals and humans: A systematic review

Authors: Guan, L; Eisenmenger, A; Crasta, KC; Sandalova, E; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/348486

Thesis Advances in clinical application of lipidomics in healthy ageing and healthy longevity medicine

Ademowo, OS; Wenk, MR; Maier, AB · 2024 · University of Melbourne · DOI

Full title: Advances in clinical application of lipidomics in healthy ageing and healthy longevity medicine

Authors: Ademowo, OS; Wenk, MR; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349925

Thesis The transcriptome as early marker of diet-related health : evidence in energy restriction studies in humans

van Bussel, Inge P.G. · 2017 · Wageningen University & Research · DOI

Full title: The transcriptome as early marker of diet-related health : evidence in energy restriction studies in humans

Authors: van Bussel, Inge P.G.

Year: 2017

Venue: Wageningen University & Research

DOI: https://research.wur.nl/en/publications/the-transcriptome-as-early-marker-of-diet-related-health-evidence

Thesis Stress, cell senescence and organismal ageing

de Magalhaes, Joao Pedro; Passos, Joao F · 2018 · University of Liverpool · DOI

Full title: Stress, cell senescence and organismal ageing

Authors: de Magalhaes, Joao Pedro; Passos, Joao F

Year: 2018

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3008468

Thesis ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Yew, MJ; Heywood, SE; Ng, J et al. · 2024 · University of Melbourne · DOI

Full title: ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Authors: Yew, MJ; Heywood, SE; Ng, J; West, OM; Pal, M; Kueh, A; Lancaster, GI; Myers, S; Yang, C; Liu, Y; Reibe, S; Mellett, NA; Meikle, PJ; Febbraio, MA; Greening, DW; Drew, BG; Henstridge, DC

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/351350

Thesis Testing the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim

Sandalova, E; Li, H; Guan, L et al. · 2024 · University of Melbourne · DOI

Full title: Testing the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim

Authors: Sandalova, E; Li, H; Guan, L; Raj, SD; Lim, TG; Tian, E; Kennedy, BK; Maier, AB

Year: 2024

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/349617

Thesis Genome wide analysis of small heat shock proteins involved in yeast ageing

Bloxam, Leanne · University of Liverpool · DOI

Full title: Genome wide analysis of small heat shock proteins involved in yeast ageing

Authors: Bloxam, Leanne

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/15873/1/Thesis_final_with_title_page.pdf

Thesis The DrugAge database of aging-related drugs.

Barardo, D; Thornton, D; Thoppil, H et al. · 2017 · University of Liverpool · DOI

Full title: The DrugAge database of aging-related drugs.

Authors: Barardo, D; Thornton, D; Thoppil, H; Walsh, M; Sharifi, S; Ferreira, S; Anžič, A; Fernandes, M; Monteiro, P; Grum, T; Cordeiro, R; De-Souza, EA; Budovsky, A; Araujo, N; Gruber, J; Petrascheck, M; Fraifeld, VE; Zhavoronkov, A; Moskalev, A; de Magalhães, JP

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3006601/1/DrugAge_AgingCell2.doc

Thesis The Business of Anti-Aging Science

de Magalhaes, Joao Pedro; Stevens, Michael; Thornton, Daniel · 2017 · University of Liverpool · DOI

Full title: The Business of Anti-Aging Science

Authors: de Magalhaes, Joao Pedro; Stevens, Michael; Thornton, Daniel

Year: 2017

Venue: University of Liverpool

DOI: https://livrepository.liverpool.ac.uk/3008938/1/aging_business_TrendsBiotech_revised_final.docx

Thesis The costs and benefits of senotherapeutics for human health

Raffaele, Marco; Vinciguerra, Manlio · 2022 · University of Liverpool · DOI

Full title: The costs and benefits of senotherapeutics for human health

Authors: Raffaele, Marco; Vinciguerra, Manlio

Year: 2022

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3167981

Thesis Does a consequent calorie restriction function in a life-prolonging manner?

Weiss, J; Hauner, H · 2006 · Technical University of Munich (TUM) · DOI

Full title: Does a consequent calorie restriction function in a life-prolonging manner?

Authors: Weiss, J;Hauner, H

Year: 2006

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1330189

Thesis Autophagy promotes cell survival by maintaining NAD levels

Kataura, Tetsushi; Sedlackova, Lucia; Otten, Elsje G et al. · 2022 · University of Liverpool · DOI

Full title: Autophagy promotes cell survival by maintaining NAD levels

Authors: Kataura, Tetsushi; Sedlackova, Lucia; Otten, Elsje G; Kumari, Ruchika; Shapira, David; Scialo, Filippo; Stefanatos, Rhoda; Ishikawa, Kei-ichi; Kelly, George; Seranova, Elena; Sun, Congxin; Maetzel, Dorothea; Kenneth, Niall; Trushin, Sergey; Zhang, Tong; Trushina, Eugenia; Bascom, Charles C; Tasseff, Ryan; Isfort, Robert J; Oblong, John E; Miwa, Satomi; Lazarou, Michael; Jaenisch, Rudolf; Imoto, Masaya; Saiki, Shinji; Papamichos-Chronakis, Manolis; Manjithaya, Ravi; Maddocks, Oliver DK; Sanz, Alberto; Sarkar, Sovan; Korolchuk, Viktor I

Year: 2022

Venue: University of Liverpool

DOI: oai:livrepository.liverpool.ac.uk:3166360

Thesis Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D.P., Horsch, M., Schröder, S., Adler, T., Afonso, L.C., Aguilar-Pimentel, J.A., Becker, L., Garrett, L., Hans, W., Hettich, M.M., Holtmeier, R., Hölter, S.M., Moreth, K., Prehn, C., Puk, O., Rácz, I., Rathkolb, B., Rozman, J., Naton, B., Ordemann, R., Adamski, J., Beckers, J., Bekeredjian, R., Busch, D.H., Ehninger, G., Graw, J., Höfler, H., Klingenspor, M., Klopstock, T., Ollert, M., Stypmann, J., Wolf, E., Wurst, W., Zimmer, A., Fuchs, H., Gailus-Durner, V., De Angelis, M.H., Ehninger, D. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging

Authors: Neff, F., Flores-Dominguez, D., Ryan, D.P., Horsch, M., Schröder, S., Adler, T., Afonso, L.C., Aguilar-Pimentel, J.A., Becker, L., Garrett, L., Hans, W., Hettich, M.M., Holtmeier, R., Hölter, S.M., Moreth, K., Prehn, C., Puk, O., Rácz, I., Rathkolb, B., Rozman, J., Naton, B., Ordemann, R., Adamski, J., Beckers, J., Bekeredjian, R., Busch, D.H., Ehninger, G., Graw, J., Höfler, H., Klingenspor, M., Klopstock, T., Ollert, M., Stypmann, J., Wolf, E., Wurst, W., Zimmer, A., Fuchs, H., Gailus-Durner, V., De Angelis, M.H., Ehninger, D.

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1346697

Thesis Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

Xie, K.; Neff, F.; Markert, A. et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

Authors: Xie, K.;Neff, F.;Markert, A.;Rozman, J.;Aguilar-Pimentel, J. A.;Amarie, O. V.;Becker, L.;Brommage, R.;Garrett, L.;Henzel, K. S.;Holter, S. M.;Janik, D.;Lehmann, I.;Moreth, K.;Pearson, B. L.;Racz, I.;Rathkolb, B.;Ryan, D. P.;Schroder, S.;Treise, I.;Bekeredjian, R.;Busch, D. H.;Graw, J.;Ehninger, G.;Klingenspor, M.;Klopstock, T.;Ollert, M.;Sandholzer, M.;Schmidt-Weber, C.;Weiergraber, M.;Wolf, E.;Wurst, W.;Zimmer, A.;Gailus-Durner, V.;Fuchs, H.;Hrabe de Angelis, M.;Ehninger, D.

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1431347

Thesis Rapamycin extends murine lifespan but has limited effects on aging.

Neff, F; Flores-Dominguez, D; Ryan, DP et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging.

Authors: Neff, F;Flores-Dominguez, D;Ryan, DP;Horsch, M;Schröder, S;Adler, T;Afonso, LC;Aguilar-Pimentel, JA;Becker, L;Garrett, L;Hans, W;Hettich, MM;Holtmeier, R;Hölter, SM;Moreth, K;Prehn, C;Puk, O;Racz, I;Rathkolb, B;Rozman, J;Naton, B;Ordemann, R;Adamski, J;Beckers, J;Bekeredjian, R;Busch, DH;Ehninger, G;Graw, J;Höfler, H;Klingenspor, M;Klopstock, T;Ollert, M;Stypmann, J;Wolf, E;Wurst, W;Zimmer, A;Fuchs, H;Gailus-Durner, V;Hrabé de Angelis, M;Ehninger, D

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1210812

Thesis Rapamycin extends murine lifespan but has limited effects on aging

Neff, F.; Flores-Dominguez, D.; Ryan, D. P. et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging

Authors: Neff, F.;Flores-Dominguez, D.;Ryan, D. P.;Horsch, M.;Schröder, S.;Adler, T.;Afonso, L. C.;Aguilar-Pimentel, J. A.;Becker, L.;Garrett, L.;Hans, W.;Hettich, M. M.;Holtmeier, R.;Holter, S. M.;Moreth, K.;Prehn, C.;Puk, O.;Racz, I.;Rathkolb, B.;Rozman, J.;Naton, B.;Ordemann, R.;Adamski, J.;Beckers, J.;Bekeredjian, R.;Busch, D. H.;Ehninger, G.;Graw, J.;Hofler, H.;Klingenspor, M.;Klopstock, T.;Ollert, M.;Stypmann, J.;Wolf, E.;Wurst, W.;Zimmer, A.;Fuchs, H.;Gailus-Durner, V.;Hrabé de Angelis, M.;Ehninger, D.

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1431160

Thesis Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Xie, Kan; Neff, Frauke; Markert, Astrid et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Authors: Xie, Kan;Neff, Frauke;Markert, Astrid;Rozman, Jan;Aguilar-Pimentel, Juan Antonio;Amarie, Oana Veronica;Becker, Lore;Brommage, Robert;Garrett, Lillian;Henzel, Kristin S;Hölter, Sabine M;Janik, Dirk;Lehmann, Isabelle;Moreth, Kristin;Pearson, Brandon L;Racz, Ildiko;Rathkolb, Birgit;Ryan, Devon P;Schröder, Susanne;Treise, Irina;Bekeredjian, Raffi;Busch, Dirk H;Graw, Jochen;Ehninger, Gerhard;Klingenspor, Martin;Klopstock, Thomas;Ollert, Markus;Sandholzer, Michael;Schmidt-Weber, Carsten;Weiergräber, Marco;Wolf, Eckhard;Wurst, Wolfgang;Zimmer, Andreas;Gailus-Durner, Valerie;Fuchs, Helmut;Hrab? de Angelis, Martin;Ehninger, Dan

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1439362

Thesis Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Xie, K.; Neff, F.; Markert, A. et al. · 2017 · Technical University of Munich (TUM) · DOI

Full title: Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Authors: Xie, K. ; Neff, F. ; Markert, A. ; Rozman, J. ; Aguilar-Pimentel, A. ; Amarie, O.V. ; Becker, L. ; Brommage, R. ; Garrett, L. ; Henzel, K.S. ; Hölter, S. ; Janik, D. ; Lehmann, I. ; Moreth, K. ; Pearson, B.L. ; Rácz, I. ; Rathkolb, B. ; Ryan, D.P. ; Schröder, S. ; Treise, I. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Ehninger, G. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Sandholzer, M. ; Schmidt-Weber, C.B. ; Weiergräber, M. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabé de Angelis, M. ; Ehninger, D.

Year: 2017

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1426121

Thesis Rapamycin extends murine lifespan but has limited effects on aging.

Neff, F.; Flores-Dominguez, D.; Ryan, D.P. et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging.

Authors: Neff, F. ; Flores-Dominguez, D. ; Ryan, D.P. ; Horsch, M. ; Schröder, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hettich, M.M. ; Holtmeier, R. ; Hölter, S.M. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Naton, B. ; Ordemann, R. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Ehninger, G. ; Graw, J. ; Höfler, H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Stypmann, J. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabé de Angelis, M. ; Ehniger, D.

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1425748

Thesis Rapamycin extends murine lifespan but has limited effects on aging

Neff, F.; Flores-Dominguez, D.; Ryan, D. P. et al. · 2013 · Technical University of Munich (TUM) · DOI

Full title: Rapamycin extends murine lifespan but has limited effects on aging

Authors: Neff, F.;Flores-Dominguez, D.;Ryan, D. P.;Horsch, M.;Schroder, S.;Adler, T.;Afonso, L. C.;Aguilar-Pimentel, J. A.;Becker, L.;Garrett, L.;Hans, W.;Hettich, M. M.;Holtmeier, R.;Holter, S. M.;Moreth, K.;Prehn, C.;Puk, O.;Racz, I.;Rathkolb, B.;Rozman, J.;Naton, B.;Ordemann, R.;Adamski, J.;Beckers, J.;Bekeredjian, R.;Busch, D. H.;Ehninger, G.;Graw, J.;Hofler, H.;Klingenspor, M.;Klopstock, T.;Ollert, M.;Stypmann, J.;Wolf, E.;Wurst, W.;Zimmer, A.;Fuchs, H.;Gailus-Durner, V.;Hrabe de Angelis, M.;Ehninger, D.

Year: 2013

Venue: Technical University of Munich (TUM)

DOI: https://mediatum.ub.tum.de/1431159

Thesis The Effects of Blue and Red Light on Physiological Responses Post-Exercise

Cesarz, Taylor; Notermann, Sydney; Quirt, Cassandra et al. · 2020 · University of Wisconsin-Madison · DOI

Full title: The Effects of Blue and Red Light on Physiological Responses Post-Exercise

Authors: Cesarz, Taylor; Notermann, Sydney; Quirt, Cassandra; Rojo, Eric; Schotten, Hayley; Tarr, Shelby

Year: 2020

Venue: University of Wisconsin-Madison

DOI: http://digital.library.wisc.edu/1793/80205

Thesis Cargo and Carrier Effects of Rapamycin-Loaded Perfluorocarbon Nanoparticles

Bibee, Kristin Page · 2013 · Washington University in St. Louis · DOI

Full title: Cargo and Carrier Effects of Rapamycin-Loaded Perfluorocarbon Nanoparticles

Authors: Bibee, Kristin Page

Year: 2013

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/80

Thesis Modulation of ageing characteristics with an anti-ageing compound

Hall, N · 2016 · University of Oxford - ORA · DOI

Full title: Modulation of ageing characteristics with an anti-ageing compound

Authors: Hall, N

Year: 2016

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:4cc41454-5b9f-41e9-b7fc-62f33b05cf15

Thesis The Role of eNAMPT-mediated Systemic NAD+ Biosynthesis in Aging and Lifespan

Yoshida, Mitsukuni · 2021 · Washington University in St. Louis · DOI

Full title: The Role of eNAMPT-mediated Systemic NAD+ Biosynthesis in Aging and Lifespan

Authors: Yoshida, Mitsukuni

Year: 2021

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/2475

Thesis The Role of Nicotinamide Mononucleotide and NAMPT-Mediated NAD+ Biosynthesis in the Regulation of Age-Related Cognitive Dysfunction

Johnson, Sean · 2018 · Washington University in St. Louis · DOI

Full title: The Role of Nicotinamide Mononucleotide and NAMPT-Mediated NAD+ Biosynthesis in the Regulation of Age-Related Cognitive Dysfunction

Authors: Johnson, Sean

Year: 2018

Venue: Washington University in St. Louis

DOI: https://openscholarship.wustl.edu/art_sci_etds/1544

Thesis Using pharmacological and proteomic analysis to investigate molecular pathways in cellular senescence

Walters, H · 2019 · University of Oxford - ORA · DOI

Full title: Using pharmacological and proteomic analysis to investigate molecular pathways in cellular senescence

Authors: Walters, H

Year: 2019

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:68d459fd-1972-46ba-9c7b-ded4722e913d

Thesis Exploring the possibility of improving longevity through late-life intervention

Gavriilidis, G · 2021 · University of Oxford - ORA · DOI

Full title: Exploring the possibility of improving longevity through late-life intervention

Authors: Gavriilidis, G

Year: 2021

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:1b099bd5-9db9-4976-bdaf-c25ad0805a0c

Thesis Overcoming immunosenescence: strategies to modulate DNA damage and senescence in immune cells and fibroblasts

Kell, L · 2024 · University of Oxford - ORA · DOI

Full title: Overcoming immunosenescence: strategies to modulate DNA damage and senescence in immune cells and fibroblasts

Authors: Kell, L

Year: 2024

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:323fcbc3-126a-43ed-8fca-67c888ce245d

Thesis Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

Kristensen, Jonas Møller; Larsen, Steen; Helge, Jørn Wulff et al. · 2013 · University of Copenhagen · DOI

Full title: Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

Authors: Kristensen, Jonas Møller; Larsen, Steen; Helge, Jørn Wulff; Dela, Flemming; Wojtaszewski, Jørgen

Year: 2013

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/7ae4144f-76ec-4b1f-a78f-f5ab6a992a51

Thesis ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Yew, Michael J; Heywood, Sarah E; Ng, Joe et al. · 2024 · Charles Sturt University - Research Output · DOI

Full title: ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Authors: Yew, Michael J; Heywood, Sarah E; Ng, Joe; West, Olivia M; Pal, Martin; id_orcid 0000-0002-1563-5426; Kueh, Andrew; Lancaster, Graeme I; Myers, Stephen; Yang, Christine; Liu, Yingying; Reibe, Saskia; Mellett, Natalie A; Meikle, Peter J; Febbraio, Mark A; Greening, David W; Drew, Brian G; Henstridge, Darren C

Year: 2024

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/e78de135-31d8-4a03-841f-22fe1c1c277c

Thesis The effects of mTOR inhibition in ischemic stroke

Schneider, AM · 2022 · University of Oxford - ORA · DOI

Full title: The effects of mTOR inhibition in ischemic stroke

Authors: Schneider, AM

Year: 2022

Venue: University of Oxford - ORA

DOI: oai:ora.ox.ac.uk:uuid:eed92456-d839-4e5c-9d70-f27f5a3d635f

Thesis No, you can’t reverse ageing by injecting ‘young blood’ and fasting. But that doesn’t stop people trying

Jefferson-Buchanan, Rachael; id_orcid 0000-0002-0048-5947 · 2023 · Charles Sturt University - Research Output · DOI

Full title: No, you can’t reverse ageing by injecting ‘young blood’ and fasting. But that doesn’t stop people trying

Authors: Jefferson-Buchanan, Rachael; id_orcid 0000-0002-0048-5947

Year: 2023

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/fc2b2934-f48c-4951-b006-127e92dfca09

Thesis Mitochondria in the signaling pathways that control longevity and health span

Akbari, Mansour; Kirkwood, Thomas B L; Bohr, Vilhelm A · 2019 · University of Copenhagen · DOI

Full title: Mitochondria in the signaling pathways that control longevity and health span

Authors: Akbari, Mansour; Kirkwood, Thomas B L; Bohr, Vilhelm A

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/3b132d8e-1a31-4a70-b567-d53ae1f9ff4f

Thesis Vive la radiorésistance!:Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

Cortese, Franco; Klokov, Dmitry; Osipov, Andreyan et al. · 2018 · University of Copenhagen · DOI

Full title: Vive la radiorésistance!:Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

Authors: Cortese, Franco; Klokov, Dmitry; Osipov, Andreyan; Stefaniak, Jakub; Moskalev, Alexey; Schastnaya, Jane; Cantor, Charles; Aliper, Alexander; Ushakov, Igor; Sapetsky, Alex; Vanhaelen, Quentin; Alchinova, Irina; Karganov, Mikhail; Kovalchuk, Olga; Wilkins, Ruth; Shtemberg, Andrey; Moreels, Marjan; Baatout, Sarah; Izumchenko, Evgeny; de Magalhães, João Pedro; Artemov, Artem V.; Costes, Sylvain V.; Beheshti, Afshin; Mao, Xiao Wen; Pecaut, Michael J.; Kaminskiy, Dmitry; Ozerov, Ivan V.; Scheibye-Knudsen, Morten; Zhavoronkov, Alex

Year: 2018

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/65148826-7851-40cf-a081-b0237286774b

Thesis Red light therapy in thrombosis and hemostasis

Fan, Bingwen Eugene; Pasalic, Leonardo; Hew, Yu Yue et al. · 2025 · Charles Sturt University - Research Output · DOI

Full title: Red light therapy in thrombosis and hemostasis

Authors: Fan, Bingwen Eugene; Pasalic, Leonardo; Hew, Yu Yue; Lippi, Giuseppe; Favaloro, Emmanuel J.; id_orcid 0000-0002-2103-1661

Year: 2025

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/392a0b2a-182c-4295-9e74-b34afe026ad1

Thesis Obesity, sirtuins, cardiorespiratory fitness, and metabolic health : modeling acquired environmental effects

Jukarainen, Sakari · 2017 · University of Helsinki (HELDA) · DOI

Full title: Obesity, sirtuins, cardiorespiratory fitness, and metabolic health : modeling acquired environmental effects

Authors: Jukarainen, Sakari

Year: 2017

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/225943

Thesis Metabolic and cellular effects of calorie restriction and whey proteins in experimental obesity

Kurki, Eveliina · 2013 · University of Helsinki (HELDA) · DOI

Full title: Metabolic and cellular effects of calorie restriction and whey proteins in experimental obesity

Authors: Kurki, Eveliina

Year: 2013

Venue: University of Helsinki (HELDA)

DOI: http://hdl.handle.net/10138/38266

Thesis Targeting Cellular Senescence and NAD + Metabolism Disruption in Early-Stage Chronic Kidney Disease

Chanvillard, Lucie Camille · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Targeting Cellular Senescence and NAD + Metabolism Disruption in Early-Stage Chronic Kidney Disease

Authors: Chanvillard, Lucie Camille

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/242283

Thesis Feedback regulation of CDK5/p25/SIRT1 signaling by 1-methylnicotinamide

Guo, Yumeng; 郭雨濛 · 2020 · University of Hong Kong · DOI

Full title: Feedback regulation of CDK5/p25/SIRT1 signaling by 1-methylnicotinamide

Authors: Guo, Yumeng; 郭雨濛

Year: 2020

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/280071

Thesis Role of adipose SIRT1 in regulating systemic energy metabolism

Xu, Cheng; 徐承 · 2013 · University of Hong Kong · DOI

Full title: Role of adipose SIRT1 in regulating systemic energy metabolism

Authors: Xu, Cheng; 徐承

Year: 2013

Venue: University of Hong Kong

DOI: https://hub.hku.hk/handle/10722/183054

Thesis Stimulating angiogenesis and post-ischemic tissue repair: Optimizing photobiomodulation parameters in vivo

Joniová, Jaroslava; Bechelli, Clémence; Déglise, Sébastien et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Stimulating angiogenesis and post-ischemic tissue repair: Optimizing photobiomodulation parameters in vivo

Authors: Joniová, Jaroslava; Bechelli, Clémence; Déglise, Sébastien; Allagnat, Florent; Wagnières, Georges

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/251765

Thesis Photobiomodulation Effects on Cellular Metabolism: An In Vitro Study Using NAD(P)H and FAD Fluorescence Lifetime Imaging

Kazemiraad, Cyrus · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Photobiomodulation Effects on Cellular Metabolism: An In Vitro Study Using NAD(P)H and FAD Fluorescence Lifetime Imaging

Authors: Kazemiraad, Cyrus

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/255351

Thesis NAD+ precursor supplementation in human ageing: clinical evidence and challenges

Vinten, Kasper T.; Trętowicz, Maria M.; Coskun, Evrim et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD+ precursor supplementation in human ageing: clinical evidence and challenges

Authors: Vinten, Kasper T.; Trętowicz, Maria M.; Coskun, Evrim; van Weeghel, Michel; Cantó, Carles; Zapata‐Pérez, Rubén; Janssens, Georges E.; Houtkooper, Riekelt H.

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/255036

Thesis Emerging Strategies, Applications and Challenges of Targeting Nad + in the Clinic

Zhang, Jianying; Wang, He-Ling; Lautrup, Sofie et al. · 2025 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Emerging Strategies, Applications and Challenges of Targeting Nad + in the Clinic

Authors: Zhang, Jianying; Wang, He-Ling; Lautrup, Sofie; Nilsen, Hilde Loge; Treebak, Jonas T.; Watne, Leiv Otto; Selbaek, Geir; Wu, Lindsay E.; Omland, Torbjorn; Pirinen, Eija; Cheung, Tin Cho; Wang, Jun; Ziegler, Mathias; Tysnes, Ole-Bjorn; Zapata-Perez, Ruben; Bruzzone, Santina; Canto, Carles; Deleidi, Michela; Janssens, Georges E.; Houtkooper, Riekelt H.; Scheibye-Knudsen, Morten; Koshizaka, Masaya; Yokote, Koutaro; Verdin, Eric; Bohr, Vilhelm A.; Tzoulis, Charalampos; Sinclair, David A.; Fang, Evandro Fei

Year: 2025

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/254114

Thesis Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Remie, Carlijn M. E.; Roumans, Kay H. M.; Moonen, Michiel P. B. et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Authors: Remie, Carlijn M. E.; Roumans, Kay H. M.; Moonen, Michiel P. B.; Connell, Niels J.; Havekes, Bas; Mevenkamp, Julian; Lindeboom, Lucas; de Wit, Vera H. W.; van de Weijer, Tineke; Aarts, Suzanne A. B. M.; Lutgens, Esther; Schomakers, Bauke V.; Elfrink, Hyung L.; Zapata-Perez, Ruben; Houtkooper, Riekelt H.; Auwerx, Johan; Hoeks, Joris; Schrauwen-Hinderling, Vera B.; Phielix, Esther; Schrauwen, Patrick

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/171543

Thesis Latest advances in aging research and drug discovery

Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano et al. · 2019 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Latest advances in aging research and drug discovery

Authors: Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano; Antebi, Adam; Barzilai, Nir; Bittner, Martin-Immanuel; Jensen, Martin Borch; Calkhoven, Cornelis F.; Chen, Danica; de Grey, Aubrey D. N. J.; Feige, Jerome N.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Golato, Tyler; Gudkov, Andrei V.; Hoppe, Thorsten; Kaeberlein, Matt; Katajisto, Pekka; Kennedy, Brian K.; Lal, Unmesh; Martin-Villalba, Ana; Moskalev, Alexey A.; Ozerov, Ivan; Petr, Michael A.; Reason; Rubinsztein, David C.; Tyshkovskiy, Alexander; Vanhaelen, Quentin; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2019

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/164065

Thesis Semisynthetic Biosensors for the Quantification of Nicotinamide Adenine Dinucleotides in Live Cells

Sallin, Olivier Vincent · 2018 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Semisynthetic Biosensors for the Quantification of Nicotinamide Adenine Dinucleotides in Live Cells

Authors: Sallin, Olivier Vincent

Year: 2018

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/144644

Thesis A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential

Bazhin, Arkadiy A.; Sinisi, Riccardo; De Marchi, Umberto et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential

Authors: Bazhin, Arkadiy A.; Sinisi, Riccardo; De Marchi, Umberto; Hermant, Aurelie; Sambiagio, Nicolas; Maric, Tamara; Budin, Ghyslain; Goun, Elena A.

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/174777

Thesis A biosensor for measuring NAD(+) levels at the point of care

Yu, Qiuliyang; Pourmandi, Narges; Xue, Lin et al. · 2020 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A biosensor for measuring NAD(+) levels at the point of care

Authors: Yu, Qiuliyang; Pourmandi, Narges; Xue, Lin; Gondrand, Corentin; Fabritz, Sebastian; Bardy, Daniel; Patiny, Luc; Katsyuba, Elena; Auwerx, Johan; Johnsson, Kai

Year: 2020

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/164304

Thesis Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans

Nascimento, Emmani B. M.; Moonen, Michiel P. B.; Remie, Carlijn M. E. et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans

Authors: Nascimento, Emmani B. M.; Moonen, Michiel P. B.; Remie, Carlijn M. E.; Gariani, Karim; Jorgensen, Johanna A.; Schaart, Gert; Hoeks, Joris; Auwerx, Johan; Lichtenbelt, Wouter D. van Marken; Schrauwen, Patrick

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/179688

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2021 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Soren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin Y.; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David J.; Gorbunova, Vera; de Grey, Aubrey; He, Wei-Wu; Hoeijmakers, Jan; Hoffmann, Eva; Horvath, Steve; Houtkooper, Riekelt H.; Jensen, Majken K.; Jensen, Martin Borch; Kane, Alice; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian; Karsenty, Gerard; Lamming, Dudley W.; Lee, Kai-Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura; Osborne, Brenna; Pak, Heidi H.; Parkhitko, Andrey; Raimundo, Nuno; Rando, Thomas A.; Rasmussen, Lene Juel; Reis, Carolina; Riedel, Christian G.; Franco-Romero, Anais; Schumacher, Bjoern; Sinclair, David A.; Suh, Yousin; Taub, Pam R.; Toiber, Debra; Treebak, Jonas T.; Valenzano, Dario Riccardo; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2021

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/179431

Thesis Commonly adopted caloric restriction protocols often involve malnutrition

Kowaltowski, Alicia Juliana · 2010 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Commonly adopted caloric restriction protocols often involve malnutrition

Authors: Kowaltowski, Alicia Juliana

Year: 2010

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1016/j.arr.2010.05.002

Thesis Transcriptional targets of sirtuins in the coordination of mammalian physiology

Feige, Jerome N; Auwerx, Johan · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Transcriptional targets of sirtuins in the coordination of mammalian physiology

Authors: Feige, Jerome N; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/36821

Thesis NAD(+) Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease

Chanvillard, Lucie; Tammaro, Alessandra; Sorrentino, Vincenzo · 2023 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD(+) Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease

Authors: Chanvillard, Lucie; Tammaro, Alessandra; Sorrentino, Vincenzo

Year: 2023

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/194450

Thesis Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

Feige, Jérôme N; Lagouge, Marie; Canto, Carles et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

Authors: Feige, Jérôme N; Lagouge, Marie; Canto, Carles; Strehle, Axelle; Houten, Sander M; Milne, Jill C; Lambert, Philip D; Mataki, Chikage; Elliott, Peter J; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/36641

Thesis Interference between PARPs and SIRT1: a novel approach to healthy ageing?

Cantó, Carles; Auwerx, Johan · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Interference between PARPs and SIRT1: a novel approach to healthy ageing?

Authors: Cantó, Carles; Auwerx, Johan

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/72616

Thesis AMPK regulates energy expenditure by modulating NAD(+) metabolism and SIRT1 activity

Cantó, Carles; Gerhart-Hines, Zachary; Feige, Jerome N et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: AMPK regulates energy expenditure by modulating NAD(+) metabolism and SIRT1 activity

Authors: Cantó, Carles; Gerhart-Hines, Zachary; Feige, Jerome N; Lagouge, Marie; Noriega, Lilia; Milne, Jill C; Elliott, Peter J; Puigserver, Pere; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/36572

Thesis Mitophagy in human health, ageing and disease

Picca, Anna; Faitg, Julie; Auwerx, Johan et al. · 2024 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mitophagy in human health, ageing and disease

Authors: Picca, Anna; Faitg, Julie; Auwerx, Johan; Ferrucci, Luigi; D'Amico, Davide

Year: 2024

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/204328

Thesis Caloric restriction, SIRT1 and longevity

Cantó, C; Auwerx, J · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Caloric restriction, SIRT1 and longevity

Authors: Cantó, C; Auwerx, J

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/42357

Thesis Dietary manipulation of mouse metabolism

Feige, J.N.; Lagouge, M.; Auwerx, J. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Dietary manipulation of mouse metabolism

Authors: Feige, J.N.; Lagouge, M.; Auwerx, J.

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/37273

Thesis Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

Lagouge, Marie; Argmann, Carmen; Gerhart-Hines, Zachary et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

Authors: Lagouge, Marie; Argmann, Carmen; Gerhart-Hines, Zachary; Meziane, Hamid; Lerin, Carles; Daussin, Frederic; Messadeq, Nadia; Milne, Jill; Lambert, Philip; Elliott, Peter; Geny, Bernard; Laakso, Markku; Puigserver, Pere; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/36657

Thesis The role of sirtuins in the control of metabolic homeostasis

Yu, Jiujiu; Auwerx, Johan · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The role of sirtuins in the control of metabolic homeostasis

Authors: Yu, Jiujiu; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/43819

Thesis Biological and Potential Therapeutic Roles of Sirtuin Deacetylases

Taylor, D. M.; Maxwell, M. M.; Luthi-Carter, R. et al. · 2010 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Biological and Potential Therapeutic Roles of Sirtuin Deacetylases

Authors: Taylor, D. M.; Maxwell, M. M.; Luthi-Carter, R.; Kazantsev, A. G.

Year: 2010

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/60770

Thesis Sirtuins: the 'magnificent seven', function, metabolism and longevity

Dali-Youcef, Nassim; Lagouge, Marie; Froelich, Sébastien et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Sirtuins: the 'magnificent seven', function, metabolism and longevity

Authors: Dali-Youcef, Nassim; Lagouge, Marie; Froelich, Sébastien; Koehl, Christian; Schoonjans, Kristina; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/36801

Thesis The journey of resveratrol from yeast to human

Timmers, Silvie; Auwerx, Johan; Schrauwen, Patrick · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The journey of resveratrol from yeast to human

Authors: Timmers, Silvie; Auwerx, Johan; Schrauwen, Patrick

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80600

Thesis Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timmers, Silvie; Konings, Ellen; Bilet, Lena et al. · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Authors: Timmers, Silvie; Konings, Ellen; Bilet, Lena; Houtkooper, Riekelt H.; van de Weijer, Tineke; Goossens, Gijs H.; Hoeks, Joris; van der Krieken, Sophie; Ryu, Dongryeol; Kersten, Sander; Moonen-Kornips, Esther; Hesselink, Matthijs K. C.; Kunz, Iris; Schrauwen-Hinderling, Vera B.; Blaak, Ellen E.; Auwerx, Johan; Schrauwen, Patrick

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/72608

Thesis Exploring the therapeutic space around NAD+

Houtkooper, Richardus; Auwerx, Johan · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Exploring the therapeutic space around NAD+

Authors: Houtkooper, Richardus; Auwerx, Johan

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/86227

Thesis Mitochondrial sirtuins and metabolic homeostasis

Pirinen, Eija; Lo Sasso, Giuseppe; Auwerx, Johan · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mitochondrial sirtuins and metabolic homeostasis

Authors: Pirinen, Eija; Lo Sasso, Giuseppe; Auwerx, Johan

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/87764

Thesis Calorie restriction: is AMPK a key sensor and effector?

Cantó, Carles; Auwerx, Johan · 2011 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Calorie restriction: is AMPK a key sensor and effector?

Authors: Cantó, Carles; Auwerx, Johan

Year: 2011

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/72611

Thesis Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Van De Weijer, Tineke; Phielix, Esther; Bilet, Lena et al. · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Authors: Van De Weijer, Tineke; Phielix, Esther; Bilet, Lena; Williams, Evan G.; Ropelle, Eduardo R.; Bierwagen, Alessandra; Livingstone, Roshan; Nowotny, Peter; Sparks, Lauren M.; Paglialunga, Sabina; Szendroedi, Julia; Havekes, Bas; Moullan, Norman; Pirinen, Eija; Hwang, Jong-Hee; Schrauwen-Hinderling, Vera B.; Hesselink, Matthijs K. C.; Auwerx, Johan; Roden, Michael; Schrauwen, Patrick

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/114382

Thesis Sirtuins as regulators of metabolism and healthspan

Houtkooper, Riekelt H.; Pirinen, Eija; Auwerx, Johan · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Sirtuins as regulators of metabolism and healthspan

Authors: Houtkooper, Riekelt H.; Pirinen, Eija; Auwerx, Johan

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/80144

Thesis The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

Houtkooper, Riekelt H.; Cantó, Carles; Wanders, Ronald J. et al. · 2009 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

Authors: Houtkooper, Riekelt H.; Cantó, Carles; Wanders, Ronald J.; Auwerx, Johan

Year: 2009

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/44907

Thesis Common Mechanisms for Calorie Restriction and AC5 Knockout Models of Longevity

Yan, Lin; Park, Ji Yeon; Dillinger, Jean-Guillaume et al. · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Common Mechanisms for Calorie Restriction and AC5 Knockout Models of Longevity

Authors: Yan, Lin; Park, Ji Yeon; Dillinger, Jean-Guillaume; Lorenzo, De; Mariana, S.; Yuan, Chujun; Lai, Lo; Wang, Chunbo; Ho, David; Tian, Bin; Stanley, William C.; Auwerx, Johan; Vatner, Dorothy E.; Vatner, Stephen F.

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/85981

Thesis The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Cantó, Carles; Houtkooper, Riekelt H.; Pirinen, Eija et al. · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Authors: Cantó, Carles; Houtkooper, Riekelt H.; Pirinen, Eija; Youn, Dou Y.; Oosterveer, Maaike H.; Cen, Yana; Fernandez-Marcos, Pablo J.; Yamamoto, Hiroyasu; Andreux, Pénélope A.; Cettour-Rose, Philippe; Gademann, Karl; Rinsch, Chris; Schoonjans, Kristina; Sauve, Anthony A.; Auwerx, Johan

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/81476

Thesis Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD(+)?

Cantó, Carles; Auwerx, Johan · 2012 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD(+)?

Authors: Cantó, Carles; Auwerx, Johan

Year: 2012

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/77240

Thesis The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Mouchiroud, Laurent; Houtkooper, Riekelt H.; Moullan, Norman et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Authors: Mouchiroud, Laurent; Houtkooper, Riekelt H.; Moullan, Norman; Katsyuba, Elena; Ryu, Dongryeol; Cantó, Carles; Mottis, Adrienne; Jo, Young-Suk; Viswanathan, Mohan; Schoonjans, Kristina; Guarente, Leonard; Auwerx, Johan

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/94265

Thesis Mitonuclear protein imbalance as a conserved longevity mechanism

Houtkooper, Richardus; Mouchiroud, Laurent; Ryu, Dongryeol et al. · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Mitonuclear protein imbalance as a conserved longevity mechanism

Authors: Houtkooper, Richardus; Mouchiroud, Laurent; Ryu, Dongryeol; Moullan, Norman; Katsyuba, Elena; Knott, Graham; Williams, Robert W.; Auwerx, Johan

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/92369

Thesis NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Canto, Carles; Menzies, Keir J.; Auwerx, Johan · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Authors: Canto, Carles; Menzies, Keir J.; Auwerx, Johan

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/118951

Thesis Methods of treating mitochondrial dysfunction

Alvarez, Carlos; Bai, Peter; Houtkooper, Riekelt et al. · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Methods of treating mitochondrial dysfunction

Authors: Alvarez, Carlos; Bai, Peter; Houtkooper, Riekelt; Auwerx, Johan; Mouchiroud, Laurent

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/118279

Thesis Identification of genetic determinants and pharmacological modulators of mitochondrial function

Andreux, Pénélope · 2013 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Identification of genetic determinants and pharmacological modulators of mitochondrial function

Authors: Andreux, Pénélope

Year: 2013

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/94718

Thesis An acetylation rheostat for the control of muscle energy homeostasis

Menzies, Keir; Auwerx, Johan · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: An acetylation rheostat for the control of muscle energy homeostasis

Authors: Menzies, Keir; Auwerx, Johan

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/100820

Thesis NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Cerutti, Raffaele; Pirinen, Eija; Lamperti, Costanza et al. · 2014 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Authors: Cerutti, Raffaele; Pirinen, Eija; Lamperti, Costanza; Marchet, Silvia; Sauve, Anthony A.; Li, Wei; Leoni, Valerio; Schon, Eric A.; Dantzer, Francoise; Auwerx, Johan; Viscomi, Carlo; Zeviani, Massimo

Year: 2014

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/107944

Thesis A review of the biomedical innovations for healthy longevity

Moskalev, Alexey; Anisimov, Vladimir; Aliper, Aleksander et al. · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: A review of the biomedical innovations for healthy longevity

Authors: Moskalev, Alexey; Anisimov, Vladimir; Aliper, Aleksander; Artemov, Artem; Asadullah, Khusru; Belsky, Daniel; Baranova, Ancha; De Grey, Aubrey; Dixit, Vishwa Deep; Debonneuil, Edouard; Dobrovolskaya, Eugenia; Fedichev, Peter; Fedintsev, Alexander; Fraifeld, Vadim; Franceschi, Claudio; Freer, Rosie; Fueloep, Tamas; Feige, Jerome; Gems, David; Gladyshev, Vadim; Gorbunova, Vera; Irincheeva, Irina; Jager, Sibylle; Jazwinski, S. Michal; Kaeberlein, Matt; Kennedy, Brian; Khaltourina, Daria; Kovalchuk, Igor; Kovalchuk, Olga; Kozin, Sergey; Kulminski, Alexander; Lashmanova, Ekaterina; Lezhnina, Ksenia; Liu, Guang-Hui; Longo, Valter; Mamoshina, Polina; Maslov, Alexander; De Magalhaes, Joao Pedro; Mitchell, James; Mitnitski, Arnold; Nikolsky, Yuri; Ozerov, Ivan; Pasyukova, Elena; Peregudova, Darya; Popov, Vasily; Proshkina, Ekaterina; Putin, Evgeny; Rogaev, Evgeny; Rogina, Blanka; Schastnaya, Jane; Seluanov, Andrey; Shaposhnikov, Mikhail; Simm, Andreas; Skulachev, Vladimir; Skulachev, Maxim; Solovev, Ilya; Spindler, Stephen; Stefanova, Natalia; Suh, Yousin; Swick, Andrew; Tower, John; Gudkov, Andrei V.; Vijg, Jan; Voronkov, Andrey; West, Michael; Wagner, Wolfgang; Yashin, Anatoliy; Zemskaya, Nadezhda; Zhumadilov, Zhaxybay; Zhavoronkov, Alex

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/136686

Thesis Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease

Gariani, Karim Laurent; Menzies, Keir Joe; Ryu, Dongryeol et al. · 2015 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease

Authors: Gariani, Karim Laurent; Menzies, Keir Joe; Ryu, Dongryeol; Wenger, Casey J; Wang, Xu; Ropelle, Eduardo R; Moullan, Norman; Zhang, Hongbo; Perino, Alessia; Lemos Da Silva, Vera Monica; Canto Alvarez, Carlos; Schoonjans, Kristina; Sauve, Anthony A; Lee, Ji-Young; Auwerx, Johan

Year: 2015

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/120165

Thesis Modulating NAD(+) metabolism, from bench to bedside

Katsyuba, Elena; Auwerx, Johan · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Modulating NAD(+) metabolism, from bench to bedside

Authors: Katsyuba, Elena; Auwerx, Johan

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/141182

Thesis The role of nicotinamide riboside kinases in mammalian NAD⁺ metabolism

Ratajczak, Joanna · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The role of nicotinamide riboside kinases in mammalian NAD⁺ metabolism

Authors: Ratajczak, Joanna

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/139319

Thesis NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, Hongbo; Ryu, Dongryeol; Wu, Yibo et al. · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

Authors: Zhang, Hongbo; Ryu, Dongryeol; Wu, Yibo; Gariani, Karim; Wang, Xu; Luan, Peiling; D'Amico, Davide; Ropelle, Eduardo R; Lutolf, Matthias P; Aebersold, Ruedi; Schoonjans, Kristina; Menzies, Keir J; Auwerx, Johan

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/126595

Thesis Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences

Canto, Carles · 2016 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences

Authors: Canto, Carles

Year: 2016

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/125411

Thesis Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Cohen, AA; Kennedy, BK; Anglas, U et al. · 2020 · University of Melbourne · DOI

Full title: Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Authors: Cohen, AA; Kennedy, BK; Anglas, U; Bronikowski, AM; Deelen, J; Dufour, F; Ferbeyre, G; Ferrucci, L; Franceschi, C; Frasca, D; Friguet, B; Gaudreau, P; Gladyshev, VN; Gonos, ES; Gorbunova, V; Gut, P; Ivanchenko, M; Legault, V; Lemaître, JF; Liontis, T; Liu, GH; Liu, M; Maier, AB; Nóbrega, OT; Olde Rikkert, MGM; Pawelec, G; Rheault, S; Senior, AM; Simm, A; Soo, S; Traa, A; Ukraintseva, S; Vanhaelen, Q; Van Raamsdonk, JM; Witkowski, JM; Yashin, AI; Ziman, R; Fülöp, T

Year: 2020

Venue: University of Melbourne

DOI: https://hdl.handle.net/11343/254102

Thesis The therapeutic role of NAD+ modulation in fatty liver disease

Gariani, Karim Laurent · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: The therapeutic role of NAD+ modulation in fatty liver disease

Authors: Gariani, Karim Laurent

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/139233

Thesis Role of ACMSD in regulation of NAD+ metabolism and mitochondrial function

Katsyuba, Elena · 2017 · École polytechnique fédérale de Lausanne (EPFL) · DOI

Full title: Role of ACMSD in regulation of NAD+ metabolism and mitochondrial function

Authors: Katsyuba, Elena

Year: 2017

Venue: École polytechnique fédérale de Lausanne (EPFL)

DOI: https://infoscience.epfl.ch/handle/20.500.14299/139873

Thesis Mitochondrial metabolism in aging: effect of dietary interventions

Kowaltowski, Alicia Juliana · 2012 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Mitochondrial metabolism in aging: effect of dietary interventions

Authors: Kowaltowski, Alicia Juliana

Year: 2012

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1016/j.arr.2012.03.009

Thesis Caloric restriction promotes structural and metabolic changes in the skin

Kowaltowski, Alicia Juliana · 2017 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Caloric restriction promotes structural and metabolic changes in the skin

Authors: Kowaltowski, Alicia Juliana

Year: 2017

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1016/j.celrep.2017.08.052

Thesis Caloric restriction and redox state: does this diet increase or decrease oxidant production?

Kowaltowski, Alicia Juliana · 2011 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Caloric restriction and redox state: does this diet increase or decrease oxidant production?

Authors: Kowaltowski, Alicia Juliana

Year: 2011

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1179/1351000211Y.0000000014

Thesis Randomized study of 30 days of resveratrol and caloric restriction on serum levels of sirtuin-1 in healthy subjects

Strunz, C. M. C. · 2015 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Randomized study of 30 days of resveratrol and caloric restriction on serum levels of sirtuin-1 in healthy subjects

Authors: Strunz, C. M. C.

Year: 2015

Venue: Universidade de São Paulo – USP Digital Library

DOI: http://eurheartj.oxfordjournals.org/content/ehj/36/suppl_1/849.full.pdf

Thesis Effects of caloric restriction, dietary restriction and every other day feeding on energy metabolism and redox state

Kowaltowski, Alicia Juliana · 2010 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Effects of caloric restriction, dietary restriction and every other day feeding on energy metabolism and redox state

Authors: Kowaltowski, Alicia Juliana

Year: 2010

Venue: Universidade de São Paulo – USP Digital Library

DOI: 002701620

Thesis Mitochondrial Ca2+ and functional adaptations to nutritional signals: insights from caloric restriction

Vilas-Boas, Eloisa Aparecida · 2023 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Mitochondrial Ca2+ and functional adaptations to nutritional signals: insights from caloric restriction

Authors: Vilas-Boas, Eloisa Aparecida

Year: 2023

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://www.sciencedirect.com/journal/free-radical-biology-and-medicine/vol/208/suppl/S1

Thesis Infrared-LED (850nm) illumination improve exercise tolerance and peripheral strength during aging

Bagnato, Vanderlei Salvador · 2011 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Infrared-LED (850nm) illumination improve exercise tolerance and peripheral strength during aging

Authors: Bagnato, Vanderlei Salvador

Year: 2011

Venue: Universidade de São Paulo – USP Digital Library

DOI: 002199214

Thesis Calorie restriction effects on insulin and nitric oxide signaling: implications for mitochondrial biogenesis, morphology and function

Kowaltowski, Alicia Juliana · 2012 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Calorie restriction effects on insulin and nitric oxide signaling: implications for mitochondrial biogenesis, morphology and function

Authors: Kowaltowski, Alicia Juliana

Year: 2012

Venue: Universidade de São Paulo – USP Digital Library

DOI: 002287192

Thesis Light-emitting diode therapy (photobiomodulation) effects on oxygen uptake and cardiac output dynamics during moderate exercise transitions: a randomized, crossover, double-blind, and placebo-controlled study

Hughson, Richard L. · 2018 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Light-emitting diode therapy (photobiomodulation) effects on oxygen uptake and cardiac output dynamics during moderate exercise transitions: a randomized, crossover, double-blind, and placebo-controlled study

Authors: Hughson, Richard L.

Year: 2018

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1007/s10103-018-2473-1

Thesis Autophagy and Hematopoietic Stem Cell Potential During Aging

Dellorusso, Paul Vincent · 2022 · Columbia University · DOI

Full title: Autophagy and Hematopoietic Stem Cell Potential During Aging

Authors: Dellorusso, Paul Vincent

Year: 2022

Venue: Columbia University

DOI: https://doi.org/10.7916/6njv-we26

Thesis A comprehensive phenotypic comparison of the effects of putative dietary restriction mimetics in C. elegans

Mori, Marcelo Alves da Silva · 2022 · Universidade de São Paulo – USP Digital Library · DOI

Full title: A comprehensive phenotypic comparison of the effects of putative dietary restriction mimetics in C. elegans

Authors: Mori, Marcelo Alves da Silva

Year: 2022

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://www2.sbbq.org.br/reuniao/2022/images/livro_completo.pdf

Thesis Photobiomodulation for degenerative diseases: an overview and perspectives

Bagnato, Vanderlei Salvador · 2025 · Universidade de São Paulo – USP Digital Library · DOI

Full title: Photobiomodulation for degenerative diseases: an overview and perspectives

Authors: Bagnato, Vanderlei Salvador

Year: 2025

Venue: Universidade de São Paulo – USP Digital Library

DOI: https://doi.org/10.1177/15578550251363061

Thesis Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases

Siegmund, Stephanie · 2018 · Columbia University · DOI

Full title: Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases

Authors: Siegmund, Stephanie

Year: 2018

Venue: Columbia University

DOI: https://doi.org/10.7916/D8J4050F

Thesis The mitochondrial secret(ome): Investigating mitochondrial stress-induced cell non-autonomous communication

Govindaraju, Hemna · 2025 · UNSW Sydney · DOI

Full title: The mitochondrial secret(ome): Investigating mitochondrial stress-induced cell non-autonomous communication

Authors: Govindaraju, Hemna

Year: 2025

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/105245

Thesis Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence

Braidy, N; https://orcid.org/0000-0002-0497-5572; Poljak, A et al. · 2014 · UNSW Sydney · DOI

Full title: Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence

Authors: Braidy, N ; https://orcid.org/0000-0002-0497-5572; Poljak, A ; https://orcid.org/0000-0001-9953-1984; Grant, R ; https://orcid.org/0000-0003-2050-1382; Jayasena, T; Mansour, H; Chan-Ling, T; Guillemin, GJ; Smythe, G; Sachdev, P ; https://orcid.org/0000-0002-9595-3220

Year: 2014

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_39099

Thesis Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and 6 weeks of exercise in obese female mice

Uddin, GM; Youngson, NA; https://orcid.org/0000-0003-0690-4580 et al. · 2016 · UNSW Sydney · DOI

Full title: Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and 6 weeks of exercise in obese female mice

Authors: Uddin, GM; Youngson, NA ; https://orcid.org/0000-0003-0690-4580; Sinclair, DA ; https://orcid.org/0000-0002-9936-436X; Morris, MJ ; https://orcid.org/0000-0003-2285-5117

Year: 2016

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/unsworks_43738

Thesis The DrugAge database of aging-related drugs

Barardo, Diogo; Thornton, Daniel; Thoppil, Harikrishnan et al. · 2017 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: The DrugAge database of aging-related drugs

Authors: Barardo, Diogo; Thornton, Daniel; Thoppil, Harikrishnan; Walsh, Michael; Sharifi, Samim; Ferreira, Susana; Anžič, Andreja; Fernandes, Maria; Monteiro, Patrick; Grum, Tjaša; Cordeiro, Rui; De-Souza, Evandro A.; Budovsky, Arie; Araujo, Natali; Gruber, jan; Petrascheck, Michael; Fraifeld, Vadim E.; Zhavoronkov, Alexander; Moskalev, Alexey; de Magalhães, João P.

Year: 2017

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/129629

Thesis The Metabolic Impact on Histone Acetylation and Transcription in Ageing

Peleg, Shahaf; Feller, Christian; Ladurner, Andreas G. et al. · 2016 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: The Metabolic Impact on Histone Acetylation and Transcription in Ageing

Authors: Peleg, Shahaf; Feller, Christian; Ladurner, Andreas G.; Imhof, Axel

Year: 2016

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/119741

Thesis Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing

Reiten, Ole Kristian; Wilvang, Martin Andreas; Mitchell, Sarah J. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing

Authors: Reiten, Ole Kristian; Wilvang, Martin Andreas; Mitchell, Sarah J.; Hu, Zeping; Fang, Evandro Fei

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/506217

Thesis Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

Wilkie, Stephen E.; Mulvey, Lorna; Sands, William A. et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

Authors: Wilkie, Stephen E.; Mulvey, Lorna; Sands, William A.; Marcu, Diana E.; Carter, Roderick N.; Morton, Nicholas M.; Hine, Christopher; Mitchell, James R.; Selman, Colin

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/465605

Thesis Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control

Cavinato, Maria; Madreiter-Sokolowski, Corina T.; Büttner, Sabrina et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control

Authors: Cavinato, Maria; Madreiter-Sokolowski, Corina T.; Büttner, Sabrina; Schosserer, Markus; Zwerschke, Werner; Wedel, Sophia; Grillari, Johannes; Graier, Wolfgang F.; Jansen-Dürr, Pidder

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/458310

Thesis The plasticity of ageing and the rediscovery of ground-state prevention

Blasimme, Alessandro; id_orcid0000-0001-5908-2002 · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: The plasticity of ageing and the rediscovery of ground-state prevention

Authors: Blasimme, Alessandro; id_orcid0000-0001-5908-2002

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/484276

Thesis Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Ke, Shanlin; Mitchell, Sarah J.; MacArthur, Michael R. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

Authors: Ke, Shanlin; Mitchell, Sarah J.; MacArthur, Michael R.; Kane, Alice E.; Sinclair, David A.; Venable, Emily M.; Chadaideh, Katia S.; Carmody, Rachel N.; Grodstein, Francine; Mitchell, James R.; Liu, Yangyu

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/507023

Thesis Youthful and age-related matreotypes predict drugs promoting longevity

Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Youthful and age-related matreotypes predict drugs promoting longevity

Authors: Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X.; Dakhovnik, Alexander; Wandrey, Franziska; Mozharovskyi, Pavlo; Zülli, Fred; Ewald, Collin Y.

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/528692

Thesis Age and life expectancy clocks based on machine learning analysis of mouse frailty

Schultz, Michael B.; Kane, Alice E.; Mitchell, Sarah J. et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Age and life expectancy clocks based on machine learning analysis of mouse frailty

Authors: Schultz, Michael B.; Kane, Alice E.; Mitchell, Sarah J.; MacArthur, Michael R.; Warner, Elisa; Vogel, David S.; Mitchell, James R.; Howlett, Susan E.; Bonkowski, Michael S.; Sinclair, David A.

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/465606

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2020 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V.; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Søren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin; id_orcid0000-0003-1166-4171; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David J.; Gorbunova, Vera A.; de Grey, Aubrey; He, Weiwu; Hoeijmakers, Jan H.; Hoffmann, Eva R.; Horvath, Steve M.; Houtkooper, Riekelt H.; Jensen, Majken K.; Jensen, Martin B.; Kane, Alice E.; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian K.; Karsenty, Gerard; Lamming, Dudley W.; Lee, Kai Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura J.; Osborne, Brenna; Pak, Heidi H.; Parkhitko, Andrey A.; Raimundo, Nuno; Rando, Thomas A.; Juel Rasmussen, Lene; Reis, Carolina; Riedel, Christian G.; Franco-Romero, Anais; Schumacher, Björn; Sinclair, David A.; Suh, Yousin; Taub, Pam R.; Toiber, Debra; Treebak, Jonas T.; Valenzano, Dario R.; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2020

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/466960

Thesis Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1‐imidazoline receptor

Bennett, Dominic F.; Goyala, Anita; Statzer, Cyril et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1‐imidazoline receptor

Authors: Bennett, Dominic F.; Goyala, Anita; Statzer, Cyril; Beckett, Charles W.; Tyshkovskiy, Alexander; Gladyshev, Vadim N.; Ewald, Collin; id_orcid0000-0003-1166-4171; de Magalhães, João Pedro

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/596274

Thesis End-of-life targeted degradation of DAF-2 insulin/IGF-1 receptor promotes longevity free from growth-related pathologies

Venz, Richard; Pekec, Tina; Katic, Iskra et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: End-of-life targeted degradation of DAF-2 insulin/IGF-1 receptor promotes longevity free from growth-related pathologies

Authors: Venz, Richard; Pekec, Tina; Katic, Iskra; Ciosk, Rafal; Ewald, Collin; id_orcid0000-0003-1166-4171

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/510861

Thesis Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Statzer, Cyrill; Reichert, Peter; Dual, Jürg et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Authors: Statzer, Cyrill; Reichert, Peter; Dual, Jürg; id_orcid0000-0001-5861-9058; Ewald, Collin; id_orcid0000-0001-5861-9058

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/525654

Thesis Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Statzer, Cyril; Reichert, Peter; Dual, Jürg et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Authors: Statzer, Cyril; Reichert, Peter; Dual, Jürg; id_orcid0000-0001-5861-9058; Ewald, Collin; id_orcid0000-0001-5861-9058

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/537535

Thesis Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial

Grundler, Franziska; Viallon, Magalie; Mesnage, Robin et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial

Authors: Grundler, Franziska; Viallon, Magalie; Mesnage, Robin; Ruscica, Massimiliano; von Schacky, Clemens; Madeo, Frank; Hofer, Sebastian J.; Mitchell, Sarah J.; Croisille, Pierre; Wilhelmi de Toledo, Françoise

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/586169

Thesis Youthful and age-related matreotypes predict drugs promoting longevity

Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X. et al. · 2021 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Youthful and age-related matreotypes predict drugs promoting longevity

Authors: Statzer, Cyril; Jongsma, Elisabeth; Liu, Sean X.; Dakhovnik, Alexander

Year: 2021

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/500377

Thesis Meeting Report: Aging Research and Drug Discovery

Meron, Esther; Thaysen, Maria; Angeli, Suzanne et al. · 2022 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Meeting Report: Aging Research and Drug Discovery

Authors: Meron, Esther; Thaysen, Maria; Angeli, Suzanne; Antebi, Adam; Barzilai, Nir; Baur, Joseph A.; Bekker-Jensen, Simon; Birkisdottir, Maria; Bischof, Evelyne; Bruening, Jens; Brunet, Anne; Buchwalter, Abigail; Cabreiro, Filipe; Cai, Shiqing; Chen, Brian H.; Ermolaeva, Maria; Ewald, Collin; id_orcid0000-0003-1166-4171; Ferrucci, Luigi; Florian, Maria Carolina; Fortney, Kristen; Freund, Adam; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Glass, David; Golato, Tyler; Gorbunova, Vera; Hoejimakers, Jan; Houtkooper, Riekelt H.; Jager, Sibylle; Jaksch, Frank; Janssens, Georges; Borch Jensen, Martin; Kaeberlein, Matt; Karsenty, Gerard; de Keizer, Peter; Kennedy, Brian; Kirkland, James L.; Kjaer, Michael; Kroemer, Guido; Lee, Kai Fu; Lemaitre, Jean-Marc; Liaskos, David; Longo, Valter D.; Lu, Yu-Xuan; MacArthur, Michael R.; Maier, Andrea B.; Manakanatas, Christina; Mitchell, Sarah J.; Moskalev, Alexey; Niedernhofer, Laura; Ozerov, Ivan; Partridge, Linda; Passegué, Emmanuelle; Petr, Michael A.; Peyer, James; Radenkovic, Dina; Rando, Thomas A.; Rattan, Suresh; Riedel, Christian G.; Rudolph, Lenhard; Ai, Ruixue; Serrano, Manuel; Schumacher, Björn; Sinclair, David A.; Smith, Ryan; Suh, Yousin; Taub, Pam; Trapp, Alexandre; Trendelenburg, Anne-Ulrike; Valenzano, Dario Riccardo; Verburgh, Kris; Verdin, Eric; Vijg, Jan; Westendorp, Rudi G.J.; Zonari, Alessandra; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2022

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/532272

Thesis Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

Knufinke, Marie; MacArthur, Michael R.; Ewald, Collin et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

Authors: Knufinke, Marie; MacArthur, Michael R.; Ewald, Collin; id_orcid0000-0003-1166-4171; Mitchell, Sarah J.

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/641207

Thesis Translational longevity medicine: a Swiss perspective in an ageing country

Ruckstuhl, Marco M.; Bischof, Evelyne; Blatch, Dana et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Translational longevity medicine: a Swiss perspective in an ageing country

Authors: Ruckstuhl, Marco M.; Bischof, Evelyne; Blatch, Dana; Buhayer, Aliki; Goldhahn, Jörg; id_orcid0000-0003-0012-0494; Battegay, Edouard; Tichelli, Andre; Ewald, Collin; id_orcid0000-0003-0012-0494

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/622120

Thesis Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan

Sharma, Arastu; Chabloz, Sophie; Lapides, Rebecca A. et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan

Authors: Sharma, Arastu; Chabloz, Sophie; Lapides, Rebecca A.; Roider, Elisabeth; Ewald, Collin; id_orcid0000-0003-1166-4171

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/596679

Thesis Effects of caloric restriction and the administration of sodium butyrate in aging: implications on learning, memory, and hippocampal inflammation

Galofré López, Neus · 2025 · Universitat Autònoma de Barcelona (TDX) · DOI

Full title: Effects of caloric restriction and the administration of sodium butyrate in aging: implications on learning, memory, and hippocampal inflammation

Authors: Galofré López, Neus

Year: 2025

Venue: Universitat Autònoma de Barcelona (TDX)

DOI: http://hdl.handle.net/10803/695969

Thesis AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

Vidovic, Tinka; Dakhovnik, Alexander; Hrabovskyi, Oleksii et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

Authors: Vidovic, Tinka; Dakhovnik, Alexander; Hrabovskyi, Oleksii; MacArthur, Michael R.; Ewald, Collin; id_orcid0000-0003-1166-4171

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/613532

Thesis Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity

Martinović, Anđela; Mantovani, Matilde; Trpchevska, Natalia et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity

Authors: Martinović, Anđela; Mantovani, Matilde; Trpchevska, Natalia; Novak, Eva; Milev, Nikolay B.; Bode, Leonie; Ewald, Collin; id_orcid0000-0003-1166-4171; Bischof, Evelyne; Reichmuth, Tobias; Lapides, Rebecca; Navarini, Alexander; Saravi, Babak; Roider, Elisabeth

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/711419

Thesis AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

Vidovic, Tinka; Dakhovnik, Alexander; MacArthur, Michael R. et al. · 2023 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

Authors: Vidovic, Tinka; Dakhovnik, Alexander; MacArthur, Michael R.; Ewald, Collin Y.

Year: 2023

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/648270

Thesis Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Teuscher, Alina C.; Statzer, Cyril; Goyala, Anita et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Authors: Teuscher, Alina C.; Statzer, Cyril; Goyala, Anita; Domenig, Seraina A.; Schoen, Ingmar; Hess, Max; Hofer, Alexander M.; Fossati, Andrea; id_orcid0000-0001-5170-4903; Vogel, Viola; Goksel, Orcun; id_orcid0000-0001-5170-4903; Aebersold, Rudolf; id_orcid0000-0001-5170-4903; Ewald, Collin; id_orcid0000-0001-5170-4903

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/652360

Thesis Systemic and transcriptional response to intermittent fasting and fasting-mimicking diet in mice

Michenthaler, Helene; Duszka, Kalina; Reinisch, Isabel et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Systemic and transcriptional response to intermittent fasting and fasting-mimicking diet in mice

Authors: Michenthaler, Helene; Duszka, Kalina; Reinisch, Isabel; Galhuber, Markus; Moyschewitz, Elisabeth; Stryeck, Sarah; Madl, Tobias; Prokesch, Andreas; Krstic, Jelena

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/707801

Thesis Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice

Kiesworo, Kevin; Agius, Thomas; MacArthur, Michael R. et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice

Authors: Kiesworo, Kevin; Agius, Thomas; MacArthur, Michael R.; Lambelet, Martine; Lyon, Arnaud; Zhang, Jing; Turiel, Guillermo; Fan, Zheng; d'Almeida, Sènan; Uygun, Korkut; Yeh, Heidi; Déglise, Sébastien; De Bock, Katrien; id_orcid0000-0001-8232-4663; Mitchell, Sarah J.; Ocampo, Alejandro; Allagnat, Florent; Longchamp, Alban

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/716068

Thesis D-Glucosamine supplementation extends life span of nematodes and of ageing mice: 10.1038/ncomms4563

Weimer, Sandra; Priebs, Josephine; Kuhlow, Doreen et al. · 2014 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: D-Glucosamine supplementation extends life span of nematodes and of ageing mice: 10.1038/ncomms4563

Authors: Weimer, Sandra; Priebs, Josephine; Kuhlow, Doreen; Groth, Marco; Priebe, Steffen; Mansfeld, Johannes; Merry, Troy L.; Dubuis, Sébastien; Laube, Beate; Pfeiffer, Andreas F.; Schulz, Tim J.; Guthke, Reinhard; Platzer, Matthias; Zamboni, Nicola; id_orcid0000-0003-1271-1021; Zarse, Kim; Ristow, Michael; id_orcid0000-0003-1271-1021

Year: 2014

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/83876

Thesis Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Liebich, Alina; Zheng, Shenglin; Schachner, Theresa et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Authors: Liebich, Alina; Zheng, Shenglin; Schachner, Theresa; id_orcid0000-0002-5505-8811; Mair, Jacqueline Louise; id_orcid0000-0002-5505-8811; Jovanova, Mia; Müller-Riemenschneider, Falk; Kowatsch, Tobias; id_orcid0000-0002-5505-8811

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/690389

Thesis Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension

Schmeisser, Sebastian; Priebe, Steffen; Groth, Marco et al. · 2013 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension

Authors: Schmeisser, Sebastian; Priebe, Steffen; Groth, Marco; Monajembashi, Shamci; Hemmerich, Peter; Guthke, Reinhard; Platzer, Matthias; Ristow, Michael; id_orcid0000-0003-2109-2453

Year: 2013

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/78686

Thesis NAD⁺ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Wang, Yu-Jen; Gaul, Daniel S.; Gorica, Era et al. · 2025 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: NAD⁺ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Authors: Wang, Yu-Jen; Gaul, Daniel S.; Gorica, Era; Pahla, Jürgen; Wang, Zeneng; Mohammed, Shafeeq; id_orcid0000-0003-2365-5037; Dahlby, Tina; id_orcid0000-0003-2365-5037; Dietrich, Elisa; Osto, Elena; Gariani, Karim; Costantino, Sarah; Winnik, Stephan; Stein, Sokrates; Hazen, Stanley L.; Ruschitzka, Frank; Auwerx, Johan; Matter, Christian M.

Year: 2025

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/731175

Thesis Nutrition and Healthy Ageing: Calorie Restriction or Polyphenol-Rich “MediterrAsian” Diet?

Pallauf, Kathrin; Giller, Katrin; Huebbe, Patricia et al. · 2013 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Nutrition and Healthy Ageing: Calorie Restriction or Polyphenol-Rich “MediterrAsian” Diet?

Authors: Pallauf, Kathrin; Giller, Katrin; Huebbe, Patricia; Rimbach, Gerald

Year: 2013

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/81985

Thesis Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

Lyu, Yu-Xuan; Fu, Qiang; Wilczok, Dominika et al. · 2024 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

Authors: Lyu, Yu-Xuan; Fu, Qiang; Wilczok, Dominika; Ying, Kejun; King, Aaron; Antebi, Adam; Vojta, Aleksandar; Stolzing, Alexandra; Moskalev, Alexey; Georgievskaya, Anastasia; Maier, Andrea B.; Olsen, Andrea; Groth, Anja; Simon, Anna Katharina; Brunet, Anne; Jamil, Aisyah; Kulaga, Anton; Bhatti, Asif; Yaden, Benjamin; Klarlund Pedersen, Bente; Ewald, Collin; id_orcid0000-0003-1166-4171; et al.

Year: 2024

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/711420

Thesis Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)

Ristow, Michael; id_orcid0000-0003-2109-2453; Schmeisser, Kathrin · 2014 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)

Authors: Ristow, Michael; id_orcid0000-0003-2109-2453; Schmeisser, Kathrin

Year: 2014

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/84765

Thesis PARP9 Supports p62-Mediated Autophagy Which Sustains Mitochondrial NADH/NADPH Levels

Muskalla, Lukas · 2024 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: PARP9 Supports p62-Mediated Autophagy Which Sustains Mitochondrial NADH/NADPH Levels

Authors: Muskalla, Lukas

Year: 2024

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/222765

Thesis Extension of Life Span by Impaired Glucose Metabolism in Caenorhabditis elegans Is Accompanied by Structural Rearrangements of the Transcriptomic Network

Priebe, Steffen; Menzel, Uwe; Zarse, Kim et al. · 2013 · ETH Zurich (Swiss Federal Institute of Technology in Zurich) · DOI

Full title: Extension of Life Span by Impaired Glucose Metabolism in Caenorhabditis elegans Is Accompanied by Structural Rearrangements of the Transcriptomic Network

Authors: Priebe, Steffen; Menzel, Uwe; Zarse, Kim; Groth, Marco; Platzer, Matthias; Ristow, Michael; id_orcid0000-0003-2109-2453; Guthke, Reinhard

Year: 2013

Venue: ETH Zurich (Swiss Federal Institute of Technology in Zurich)

DOI: http://hdl.handle.net/20.500.11850/78685

Thesis Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

Altmeyer, M; Hottiger, Michael O; https://orcid.org/0000-0002-7323-2270 · 2009 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

Authors: Altmeyer, M; Hottiger, Michael O; https://orcid.org/0000-0002-7323-2270

Year: 2009

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/51502

Thesis Regulation of Glucose Metabolism by NAD$^{+}$ and ADP-Ribosylation

Hopp, Ann-Katrin; Grüter, Patrick; Hottiger, Michael O et al. · 2019 · Vetsuisse Faculty Bern and Zurich · DOI

Full title: Regulation of Glucose Metabolism by NAD$^{+}$ and ADP-Ribosylation

Authors: Hopp, Ann-Katrin; Grüter, Patrick; Hottiger, Michael O; https://orcid.org/0000-0002-7323-2270

Year: 2019

Venue: Vetsuisse Faculty Bern and Zurich

DOI: oai:www.zora.uzh.ch:20.500.14742/169252

Thesis Artificial intelligence for aging and longevity research:Recent advances and perspectives

Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin et al. · 2019 · University of Copenhagen · DOI

Full title: Artificial intelligence for aging and longevity research:Recent advances and perspectives

Authors: Zhavoronkov, Alex; Mamoshina, Polina; Vanhaelen, Quentin; Scheibye-Knudsen, Morten; Moskalev, Alexey; Aliper, Alex

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/743e08c3-8932-4394-85df-3f7c159b12f2

Thesis Mitochondrial function in liver cells is resistant to perturbations in NAD + salvage capacity

Dall, Morten; Trammell, Samuel A. J.; Asping, Magnus et al. · 2019 · University of Copenhagen · DOI

Full title: Mitochondrial function in liver cells is resistant to perturbations in NAD + salvage capacity

Authors: Dall, Morten; Trammell, Samuel A. J.; Asping, Magnus; Hassing, Anna S; Agerholm, Marianne; Vienberg, Sara G; Gillum, Matthew P; Larsen, Steen; Treebak, Jonas T.

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/9652366a-5b7b-47ed-b9f6-4632f07430f2

Thesis Interventions for age-related diseases:Shifting the paradigm

Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra et al. · 2016 · University of Copenhagen · DOI

Full title: Interventions for age-related diseases:Shifting the paradigm

Year: 2016

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/aa40080c-5965-4caf-93fb-88e42e79ce83

Thesis Aging and drug discovery

Bakula, Daniela; Aliper, Alexander M.; Mamoshina, Polina et al. · 2018 · University of Copenhagen · DOI

Full title: Aging and drug discovery

Authors: Bakula, Daniela; Aliper, Alexander M.; Mamoshina, Polina; Petr, Michael A.; Teklu, Amanuel; Baur, Joseph A.; Campisi, Judith; Ewald, Collin Y.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Kovalchuk, Olga; Lamming, Dudley W.; Luijsterburg, Martijn S.; Martín-Montalvo, Alejandro; Maudsley, Stuart; Mkrtchyan, Garik V.; Moskalev, Alexey; Jay Olshansky, S.; Ozerov, Ivan V.; Pickett, Alexander; Ristow, Michael; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2018

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/482cf743-9684-469f-95cf-421b51dafa33

Thesis A Biological Age Model Designed for Health Promotion Interventions:Protocol for an Interdisciplinary Study for Model Development

Husted, Karina Louise Skov; Fogelstrøm, Mathilde; Hulst, Pernille et al. · 2020 · Technical University of Denmark (DTU) · DOI

Full title: A Biological Age Model Designed for Health Promotion Interventions:Protocol for an Interdisciplinary Study for Model Development

Authors: Husted, Karina Louise Skov; Fogelstrøm, Mathilde; Hulst, Pernille; Brink-Kjær, Andreas; id_orcid 0000-0002-2872-0929; Henneberg, Kaj-Åge; id_orcid 0000-0001-9418-6587; Sorensen, Helge Bjarup Dissing; id_orcid 0000-0001-5716-7600; Dela, Flemming; Helge, Jørn Wulff

Year: 2020

Venue: Technical University of Denmark (DTU)

DOI: https://orbit.dtu.dk/en/publications/a2b1809d-e4b3-463f-8106-cc3530724de7

Thesis Emerging neuroprotective effect of metformin in Parkinson's disease:A molecular crosstalk

Paudel, Yam Nath; Angelopoulou, Efthalia; Piperi, Christina et al. · 2020 · Charles Sturt University - Research Output · DOI

Full title: Emerging neuroprotective effect of metformin in Parkinson's disease:A molecular crosstalk

Authors: Paudel, Yam Nath; Angelopoulou, Efthalia; Piperi, Christina; Shaikh, Mohd. Farooq; id_orcid 0000-0001-9865-6224; Othman, Iekhsan

Year: 2020

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/9f17a857-0161-490c-a783-13ec9375c9a0

Thesis Latest advances in aging research and drug discovery

Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano et al. · 2019 · University of Copenhagen · DOI

Full title: Latest advances in aging research and drug discovery

Authors: Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano; Antebi, Adam; Barzilai, Nir; Bittner, Martin Immanuel; Jensen, Martin Borch; Calkhoven, Cornelis F.; Chen, Danica; de Grey, Aubrey D.N.J.; Feige, Jerome N.; Georgievskaya, Anastasia; Gladyshev, Vadim N.; Golato, Tyler; Gudkov, Andrei V.; Hoppe, Thorsten; Kaeberlein, Matt; Katajisto, Pekka; Kennedy, Brian K.; Lal, Unmesh; Martin-Villalba, Ana; Moskalev, Alexey A.; Ozerov, Ivan; Petr, Michael A.; Reason; Rubinsztein, David C.; Tyshkovskiy, Alexander; Vanhaelen, Quentin; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2019

Venue: University of Copenhagen

DOI: https://researchprofiles.ku.dk/da/publications/ba30b908-e988-4768-8b64-03619d213219

Thesis Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Kawahara, Elisa Ito [UNESP]; Bastos Maués, Nadine Helena Pelegrino [UNESP]; dos Santos, Klinsmann Carolo [UNESP] et al. · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Authors: Kawahara, Elisa Ito [UNESP]; Bastos Maués, Nadine Helena Pelegrino [UNESP]; dos Santos, Klinsmann Carolo [UNESP]; Barbanera, Pedro Octávio [UNESP]; Braga, Camila Pereira [UNESP]; Henrique Fernandes, Ana Angélica [UNESP]

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/171803

Thesis ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Yew, Michael J; Heywood, Sarah E; Ng, Joe et al. · 2024 · Charles Sturt University - Research Output · DOI

Full title: ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice

Year: 2024

Venue: Charles Sturt University - Research Output

DOI: https://researchoutput.csu.edu.au/en/publications/e78de135-31d8-4a03-841f-22fe1c1c277c

Thesis Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Kawahara, Elisa Ito [UNESP]; Pelegrino Bastos Maues, Nadine Helena [UNESP]; Santos, Klinsmann Carolo dos [UNESP] et al. · 2015 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Authors: Kawahara, Elisa Ito [UNESP]; Pelegrino Bastos Maues, Nadine Helena [UNESP]; Santos, Klinsmann Carolo dos [UNESP]; Barbanera, Pedro Octavio [UNESP]; Braga, Camila Pereira [UNESP]; Henrique Fernandes, Ana Angelica [UNESP]

Year: 2015

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://nopr.niscair.res.in/bitstream/123456789/29885/1/IJBB%2051%285%29%20365-371.pdf

Thesis Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae

Barros, M. H.; Bandy, B.; Tahara, E. B. et al. · 2014 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae

Authors: Barros, M. H.; Bandy, B.; Tahara, E. B.; Kowaltowski, A. J.

Year: 2014

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1074/jbc.M408918200

Thesis Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Kawahara, Elisa Ito [UNESP]; Maués, Nadine Helena Pelegrino Bastos [UNESP]; dos Santos, Klinsmann Carolo [UNESP] et al. · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

Authors: Kawahara, Elisa Ito [UNESP]; Maués, Nadine Helena Pelegrino Bastos [UNESP]; dos Santos, Klinsmann Carolo [UNESP]; Barbanera, Pedro Octávio [UNESP]; Braga, Camila Pereira [UNESP]; Fernandes, Ana Angélica Henrique [UNESP]

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://hdl.handle.net/11449/171707

Thesis Intermittent fasting for obesity and related disorders: Unveiling myths, facts, and presumptions

Halpern, Bruno; Mendes, Thiago Bosco [UNESP] · 2021 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Intermittent fasting for obesity and related disorders: Unveiling myths, facts, and presumptions

Authors: Halpern, Bruno; Mendes, Thiago Bosco [UNESP]

Year: 2021

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.20945/2359-3997000000322

Thesis Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging

Tahara, Erich B.; Barros, Mario H.; Oliveira, Graciele A. et al. · 2014 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging

Authors: Tahara, Erich B.; Barros, Mario H.; Oliveira, Graciele A.; Netto, Luis E. S.; Kowaltowski, Alicia J.

Year: 2014

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1096/fj.06-6686com

Thesis Acute LED irradiation does not change the anaerobic capacity and time to exhaustion during a high-intensity running effort: a double-blind, crossover, and placebo-controlled study: Effects of LED irradiation on anaerobic capacity and performance in running

Malta, Elvis De Souza [UNESP]; De Poli, Rodrigo Araujo Bonetti [UNESP]; Brisola, Gabriel Motta Pinheiro [UNESP] et al. · 2018 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Acute LED irradiation does not change the anaerobic capacity and time to exhaustion during a high-intensity running effort: a double-blind, crossover, and placebo-controlled study: Effects of LED irradiation on anaerobic capacity and performance in running

Authors: Malta, Elvis De Souza [UNESP]; De Poli, Rodrigo Araujo Bonetti [UNESP]; Brisola, Gabriel Motta Pinheiro [UNESP]; Milioni, Fabio [UNESP]; Miyagi, Willian Eiji [UNESP]; Machado, Fabiana Andrade; Zagatto, Alessandro Moura [UNESP]

Year: 2018

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1007/s10103-016-2011-y

Thesis Intermittent fasting for obesity and related disorders: unveiling myths, facts, and presumptions

Halpern, Bruno; Mendes, Thiago Bosco [UNESP] · 2021 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Intermittent fasting for obesity and related disorders: unveiling myths, facts, and presumptions

Authors: Halpern, Bruno; Mendes, Thiago Bosco [UNESP]

Year: 2021

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.20945/2359.3997000000322

Thesis Investigation of regenerative nutrology of cells/molecules to the organism: a systematic review

de Oliveira, Alessandra Leal; da Silva Teixeira, Thuany; Braga, Mariana Carolina et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Investigation of regenerative nutrology of cells/molecules to the organism: a systematic review

Authors: de Oliveira, Alessandra Leal; da Silva Teixeira, Thuany; Braga, Mariana Carolina; de Lima Azevedo, Lucas Emanuel; Crepaldi, Lara Souza; Azevedo, Renata Cristina Taveira; Cordeiro, Nathalia Galindo; Carvalho, Rodrigo siqueira de; Soares, Cristiana Alvarenga Spadinger; Filho, Idiberto José Zotarelli [UNESP]

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.54448/ijn24201

Thesis Long-term effects of photobiomodulation therapy on blood pressure in obese rats induced by a high-fat diet

Oishi, Jorge Camargo; de Moraes, Luis Henrique Oliveira; Filho, Julio Cesar Conceição et al. · 2025 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Long-term effects of photobiomodulation therapy on blood pressure in obese rats induced by a high-fat diet

Authors: Oishi, Jorge Camargo; de Moraes, Luis Henrique Oliveira; Filho, Julio Cesar Conceição; de Moraes, Thiago Francisco; Terroni, Barbara [UNESP]; de Castro, Cynthia Aparecida; Almeida-Lopes, Luciana; Rodrigues, Gerson Jhonatan

Year: 2025

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1007/s10103-023-03950-8

Thesis Mechanistic evaluation of red algal extracts that slow aging

Snare, David Joseph · 2013 · Georgia Institute of Technology · DOI

Full title: Mechanistic evaluation of red algal extracts that slow aging

Authors: Snare, David Joseph

Year: 2013

Venue: Georgia Institute of Technology

DOI: http://hdl.handle.net/1853/49050

Thesis Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence

Jia, Yan; Kang, Xin; Tan, Lishan et al. · 2021 · Hong Kong University of Science and Technology (HKUST) · DOI

Full title: Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence

Authors: Jia, Yan; Kang, Xin; Tan, Lishan; Ren, Yifei; Qu, Lei; Tang, Jiawei; Liu, Gang; Wang, Suxia; Xiong, Zuying; Yang, Li

Year: 2021

Venue: Hong Kong University of Science and Technology (HKUST)

DOI: http://repository.hkust.edu.hk/ir/Record/1783.1-110563

Thesis Autophagy of naïve CD4+T cells in aging - The role of body adiposity and physical fitness

Padilha, Camila S. [UNESP]; Kushkestani, Mehdi; Baptista, Liliana P. et al. · 2023 · Universidade Estadual Paulista (UNESP) · DOI

Full title: Autophagy of naïve CD4+T cells in aging - The role of body adiposity and physical fitness

Authors: Padilha, Camila S. [UNESP]; Kushkestani, Mehdi; Baptista, Liliana P.; Krüger, Karsten; Lira, Fábio Santos [UNESP]

Year: 2023

Venue: Universidade Estadual Paulista (UNESP)

DOI: http://dx.doi.org/10.1017/erm.2023.2

Thesis Investigating the Mechanisms of Action of Metformin at Pharmacological Dose.

Motaib, Safiyyah Abdelhak · 2021 · North Carolina State University · DOI

Full title: Investigating the Mechanisms of Action of Metformin at Pharmacological Dose.

Authors: Motaib, Safiyyah Abdelhak

Year: 2021

Venue: North Carolina State University

DOI: https://www.lib.ncsu.edu/resolver/1840.20/39231

Thesis Targeting the LXR/mTOR Signaling Axis to Modulate Autophagy in Diabetic Kidney Disease: A Novel Therapeutic Approach

Alkhansa, Sahar · 2025 · American University of Beirut · DOI

Full title: Targeting the LXR/mTOR Signaling Axis to Modulate Autophagy in Diabetic Kidney Disease: A Novel Therapeutic Approach

Authors: Alkhansa, Sahar

Year: 2025

Venue: American University of Beirut

DOI: http://hdl.handle.net/10938/35033

Thesis Age-related structural changes in the liver of old mice with SIRT1 overexpression in conjunction with NMN supplementation

Cao, Peter · 2016 · University of Sydney · DOI

Full title: Age-related structural changes in the liver of old mice with SIRT1 overexpression in conjunction with NMN supplementation

Authors: Cao, Peter

Year: 2016

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/16872

Thesis The role of macronutrient balance on appetite, metabolic health and ageing in a mouse model

Solon-Biet, Samantha Marie · 2013 · University of Sydney · DOI

Full title: The role of macronutrient balance on appetite, metabolic health and ageing in a mouse model

Authors: Solon-Biet, Samantha Marie

Year: 2013

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/10396

Thesis Evaluating the effects of a Ketogenic Diet on chemotherapy-induced DNA damage, Cellular Senescence, Apoptosis and chemotoxicity in Acute Myeloid Leukaemia (AML) patients.

Rajakumar, Gayathiri · 2025 · University of Sydney · DOI

Full title: Evaluating the effects of a Ketogenic Diet on chemotherapy-induced DNA damage, Cellular Senescence, Apoptosis and chemotoxicity in Acute Myeloid Leukaemia (AML) patients.

Authors: Rajakumar, Gayathiri

Year: 2025

Venue: University of Sydney

DOI: https://hdl.handle.net/2123/34291

Thesis The aging brain and nutrition

Wahl, Devin · 2018 · University of Sydney · DOI

Full title: The aging brain and nutrition

Authors: Wahl, Devin

Year: 2018

Venue: University of Sydney

DOI: http://hdl.handle.net/2123/20030

Thesis Metabotyping of Long-Lived Mice using H-1 NMR Spectroscopy

Wijeyesekera, A; Selman, C; Barton, RH et al. · 2017 · Imperial College London · DOI

Full title: Metabotyping of Long-Lived Mice using H-1 NMR Spectroscopy

Authors: Wijeyesekera, A; Selman, C; Barton, RH; Holmes, E; Nicholson, JK; Withers, DJ

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/52171

Thesis Enhancing autophagy by redox regulation extends lifespan in Drosophila

Lennicke, Claudia; Bjedov, Ivana; Grönke, Sebastian et al. · 2025 · Imperial College London · DOI

Full title: Enhancing autophagy by redox regulation extends lifespan in Drosophila

Authors: Lennicke, Claudia; Bjedov, Ivana; Grönke, Sebastian; Menger, Katja E; James, Andrew M; Castillo-Quan, Jorge I; van Leeuwen, Lucie AG; Foley, Andrea; Buricova, Marcela; Adcott, Jennifer; Montoya, Alex; Kramer, Holger B; Shliaha, Pavel V; Logan, Angela; Cabreiro, Filipe; Murphy, Michael P; Partridge, Linda; Cocheme, Helena

Year: 2025

Venue: Imperial College London

DOI: https://hdl.handle.net/10044/1/120684

Thesis A toolbox for the longitudinal assessment of healthspan in aging mice

Bellantuono, I; de Cabo, R; Ehninger, D et al. · 2024 · Imperial College London · DOI

Full title: A toolbox for the longitudinal assessment of healthspan in aging mice

Authors: Bellantuono, I; de Cabo, R; Ehninger, D; Di Germanio, C; Lawrie, A; Miller, J; Mitchell, SJ; Navas-Enamorado, I; Potter, PK; Tchkonia, T; Trejo, JL; Lamming, DW

Year: 2024

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000508183200005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb

Thesis Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Cabreiro, F; Au, C; Leung, KY et al. · 2016 · Imperial College London · DOI

Full title: Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Authors: Cabreiro, F; Au, C; Leung, KY; Vergara-Irigaray, N; Cochemé, HM; Noori, T; Weinkove, D; Schuster, E; Greene, ND; Gems, D

Year: 2016

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/40463

Thesis A systematic review to assess the impact of hyperbaric oxygen therapy on glycaemia in people with diabetes mellitus.

Baitule, Sudhanshu; Patel, Aaran H; Murthy, Narasimha et al. · 2023 · Imperial College London · DOI

Full title: A systematic review to assess the impact of hyperbaric oxygen therapy on glycaemia in people with diabetes mellitus.

Authors: Baitule, Sudhanshu; Patel, Aaran H; Murthy, Narasimha; Sankar, Sailesh; Kyrou, Ioannis; Ali, Asad; Randeva, Harpal S; Robbins, Tim

Year: 2023

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/34684171

Thesis mTOR links nutrients, inflammaging and lifespan

Cocheme, helena; Gil, Jesus · 2024 · Imperial College London · DOI

Full title: mTOR links nutrients, inflammaging and lifespan

Authors: Cocheme, helena; Gil, Jesus

Year: 2024

Venue: Imperial College London

DOI: https://www.nature.com/articles/s43587-024-00681-5

Thesis Drug repurposing for aging research using model organisms

Ziehm, Matthias; Kaur, Satwant; Ivanov, Dobril K et al. · 2024 · Imperial College London · DOI

Full title: Drug repurposing for aging research using model organisms

Authors: Ziehm, Matthias; Kaur, Satwant; Ivanov, Dobril K; Ballester, Pedro J; Marcus, David; Partridge, Linda; Thornton, Janet M

Year: 2024

Venue: Imperial College London

DOI: https://doi.org/10.1111%2Facel.12626

Thesis Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins

Liao, C-Y; Anderson, SS; Chicoine, NH et al. · 2017 · Imperial College London · DOI

Full title: Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins

Authors: Liao, C-Y; Anderson, SS; Chicoine, NH; Mayfield, JR; Garret, BJ; Kwok, CS; Academia, EC; Hsu, Y-M; Miller, DM; Bair, AM; Wilson, JA; Tannady, G; Stewart, EM; Adamson, SS; Wang, J; Withers, DJ; Kennedy, BK

Year: 2017

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/54238

Thesis Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy

Pryor, R; Norvaisas, P; Marinos, G et al. · 2019 · Imperial College London · DOI

Full title: Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy

Authors: Pryor, R; Norvaisas, P; Marinos, G; Best, L; Bruun Thingholm, L; Quintaneiro, L; De Haes, W; Esser, D; Waschina, S; Lujan, C; Smith, RL; Scott, T; Martinez-Martinez, D; Woodward, O; Bryson, K; Laudes, M; Lieb, W; Houtkooper, RH; Franke, A; Temmerman, L; Bjedov, I; Cocheme, Helena M; Kaleta, C; Gomes Cabreiro, Filipe

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/72748

Thesis A Pilot Randomized, Placebo Controlled, Double Blind Phase I Trial of the Novel SIRT1 Activator SRT2104 in Elderly Volunteers

Libri, V; Brown, AP; Gambarota, G et al. · 2018 · Imperial College London · DOI

Full title: A Pilot Randomized, Placebo Controlled, Double Blind Phase I Trial of the Novel SIRT1 Activator SRT2104 in Elderly Volunteers

Authors: Libri, V; Brown, AP; Gambarota, G; Haddad, G; Shields, GS; Dawes, H; Pinato, DJ; Hoffman, E; Elliot, PJ; Vlasuk, GP; Jacobson, E; Wilkins, MR; Matthews, PM

Year: 2018

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/57628

Thesis NAD+: A metabolic knob fine-tuning inflammation during senescence

Sogaard, Pia; Gil, Jesus · 2019 · Imperial College London · DOI

Full title: NAD+: A metabolic knob fine-tuning inflammation during senescence

Authors: Sogaard, Pia; Gil, Jesus

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/67940

Thesis Are we there yet? How and when specific biotechnologies will improve human health

O'Day, Elizabeth; Hosta-Rigau, Leticia; Oyarzún, Diego A et al. · 2018 · Imperial College London · DOI

Full title: Are we there yet? How and when specific biotechnologies will improve human health

Authors: O'Day, Elizabeth; Hosta-Rigau, Leticia; Oyarzún, Diego A; Okano, Hideyuki; de Lorenzo, Víctor; von Kameke, Conrad; Alsafar, Habiba; Cao, Cong; Chen, Guo-Qiang; Ji, Weizhi; Roberts, Richard J; Ronaghi, Mostafa; Yeung, Karen; Zhang, Feng; Lee, Sang Yup

Year: 2018

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/29799175

Thesis Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Page, Melissa M; Schuster, Eugene F; Mudaliar, Manikhandan et al. · 2018 · Imperial College London · DOI

Full title: Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Authors: Page, Melissa M; Schuster, Eugene F; Mudaliar, Manikhandan; Herzyk, Pawel; Withers, Dominic J; Selman, Colin

Year: 2018

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000433605000015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity

Dao, Maria Carlota; Sokolovska, Nataliya; Brazeilles, Remi et al. · 2019 · Imperial College London · DOI

Full title: A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity

Authors: Dao, Maria Carlota; Sokolovska, Nataliya; Brazeilles, Remi; Affeldt, Severine; Pelloux, Veronique; Prifti, Edi; Chilloux, Julien; Verger, Eric O; Kayser, Brandon D; Aron-Wisnewsky, Judith; Ichou, Farid; Pujos-Guillot, Estelle; Hoyles, Lesley; Juste, Catherine; Dore, Joel; Dumas, Marc-Emmanuel; Rizkalla, Salwa W; Holmes, Bridget A; Zucker, Jean-Daniel; Clement, Karine

Year: 2019

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000457808400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Burnett, Camilla; Valentini, Sara; Cabreiro, Filipe et al. · 2019 · Imperial College London · DOI

Full title: Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Authors: Burnett, Camilla; Valentini, Sara; Cabreiro, Filipe; Goss, Martin; Somogyvari, Milan; Piper, Matthew D; Hoddinott, Matthew; Sutphin, George L; Leko, Vid; McElwee, Joshua J; Vazquez-Manrique, Rafael P; Orfila, Anne-Marie; Ackerman, Daniel; Au, Catherine; Vinti, Giovanna; Riesen, Michele; Howard, Ken; Neri, Christian; Bedalov, Antonio; Kaeberlein, Matt; Soti, Csaba; Partridge, Linda; Gems, David

Year: 2019

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295080500044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis The role of ribosomal protein S6 kinases in cellular senescence, ageing and fatty liver disease

Gallage, Suchira Upeksha · 2019 · Imperial College London · DOI

Full title: The role of ribosomal protein S6 kinases in cellular senescence, ageing and fatty liver disease

Authors: Gallage, Suchira Upeksha

Year: 2019

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/75114

Thesis Treating aging: progress toward dietary restriction mimetics.

Cabreiro, Filipe; Gems, David · 2019 · Imperial College London · DOI

Full title: Treating aging: progress toward dietary restriction mimetics.

Authors: Cabreiro, Filipe; Gems, David

Year: 2019

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/21173839

Thesis Mammalian models of extended healthy lifespan

Selman, Colin; Withers, Dominic J · 2020 · Imperial College London · DOI

Full title: Mammalian models of extended healthy lifespan

Authors: Selman, Colin; Withers, Dominic J

Year: 2020

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000284718700015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Increased fidelity of protein synthesis extends lifespan

Martinez-Miguel, Victoria Eugenia; Lujan, Celia; Espie-Caullet, Tristan et al. · 2022 · Imperial College London · DOI

Full title: Increased fidelity of protein synthesis extends lifespan

Authors: Martinez-Miguel, Victoria Eugenia; Lujan, Celia; Espie-Caullet, Tristan; Martinez-Martinez, Daniel; Moore, Saul; Backes, Cassandra; Gonzalez, Suam; Galimov, Evgeniy R; Brown, Andre EX; Halic, Mario; Tomita, Kazunori; Rallis, Charalampos; von der Haar, Tobias; Cabreiro, Filipe; Bjedov, Ivana

Year: 2022

Venue: Imperial College London

DOI: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000716335200005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Moderate exercise inhibits age-related inflammation, liver steatosis, senescence, and tumorigenesis.

Bianchi, Arianna; Marchetti, Letizia; Hall, Zoe et al. · 2021 · Imperial College London · DOI

Full title: Moderate exercise inhibits age-related inflammation, liver steatosis, senescence, and tumorigenesis.

Authors: Bianchi, Arianna; Marchetti, Letizia; Hall, Zoe; Lemos, Henrique; Vacca, Michele; Paish, Hannah; Green, Kile; Elliott, Bronte; Tiniakos, Dina; Passos, João F; Jurk, Diana; Mann, Derek A; Wilson, Caroline L

Year: 2021

Venue: Imperial College London

DOI: https://www.ncbi.nlm.nih.gov/pubmed/33441438

Thesis Preclinical testing of potential therapeutics for Amyotrophic Lateral Sclerosis

Kaneb, Hannah Marlene Jostock · 2012 · Imperial College London · DOI

Full title: Preclinical testing of potential therapeutics for Amyotrophic Lateral Sclerosis

Authors: Kaneb, Hannah Marlene Jostock

Year: 2012

Venue: Imperial College London

DOI: http://hdl.handle.net/10044/1/9606

Thesis Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

Bjedov, Ivana; Cocheme, Helena M; Foley, Andrea et al. · 2021 · Imperial College London · DOI

Full title: Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

Authors: Bjedov, Ivana; Cocheme, Helena M; Foley, Andrea; Wieser, Daniela; Woodling, Nathaniel S; Castillo-Quan, Jorge Ivan; Norvaisas, Povilas; Lujan, Celia; Regan, Jenny; Toivonen, Janne M; Murphy, Michael P; Thornton, Janet; Kinghorn, Kerri J; Neufeld, Thomas P; Cabreiro, Filipe; Partridge, Linda

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000595960400005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, Garik V; Abdelmohsen, Kotb; Andreux, Penelope et al. · 2021 · Imperial College London · DOI

Full title: ARDD 2020: from aging mechanisms to interventions

Authors: Mkrtchyan, Garik V; Abdelmohsen, Kotb; Andreux, Penelope; Bagdonaite, Ieva; Barzilai, Nir; Brunak, Soren; Cabreiro, Filipe; de Cabo, Rafael; Campisi, Judith; Cuervo, Ana Maria; Demaria, Marco; Ewald, Collin Y; Fang, Evandro Fei; Faragher, Richard; Ferrucci, Luigi; Freund, Adam; Silva-Garcia, Carlos G; Georgievskaya, Anastasia; Gladyshev, Vadim N; Glass, David J; Gorbunova, Vera; de Grey, Aubrey; He, Wei-Wu; Hoeijmakers, Jan; Hoffmann, Eva; Horvath, Steve; Houtkooper, Riekelt H; Jensen, Majken K; Jensen, Martin Borch; Kane, Alice; Kassem, Moustapha; de Keizer, Peter; Kennedy, Brian; Karsenty, Gerard; Lamming, Dudley W; Lee, Kai-Fu; MacAulay, Nanna; Mamoshina, Polina; Mellon, Jim; Molenaars, Marte; Moskalev, Alexey; Mund, Andreas; Niedernhofer, Laura; Osborne, Brenna; Pak, Heidi H; Parkhitko, Andrey; Raimundo, Nuno; Rando, Thomas A; Rasmussen, Lene Juel; Reis, Carolina; Riedel, Christian G; Franco-Romero, Anais; Schumacher, Bjoern; Sinclair, David A; Suh, Yousin; Taub, Pam R; Toiber, Debra; Treebak, Jonas T; Valenzano, Dario Riccardo; Verdin, Eric; Vijg, Jan; Young, Sergey; Zhang, Lei; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten

Year: 2021

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000605608700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

Nunn, Alistair VW; Bell, Jimmy D; Guy, Geoffrey W · 2020 · Imperial College London · DOI

Full title: Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

Authors: Nunn, Alistair VW; Bell, Jimmy D; Guy, Geoffrey W

Year: 2020

Venue: Imperial College London

DOI: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000266324700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Thesis Novel nutritional intervention in health and chronic disease

Mullan, Adam William Francis · 2012 · University of Glasgow · DOI

Full title: Novel nutritional intervention in health and chronic disease

Authors: Mullan, Adam William Francis

Year: 2012

Venue: University of Glasgow

DOI: oai:theses.gla.ac.uk:3635

Thesis Effects of rapamycin on chromatin – implications for ageing and tumour suppression

Field, Adam · 2019 · University of Glasgow · DOI

Full title: Effects of rapamycin on chromatin – implications for ageing and tumour suppression

Authors: Field, Adam

Year: 2019

Venue: University of Glasgow

DOI: oai:theses.gla.ac.uk:41183

Thesis TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue

Choi, Cheoljun; Son, Yeonho; Kim, Jinyoung et al. · 2024 · Seoul National University · DOI

Full title: TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue

Authors: Choi, Cheoljun; Son, Yeonho; Kim, Jinyoung; Cho, Yoon Keun; Saha, Abhirup; Kim, Minsu; Im, Hyeonyeong; Kim, Kyungmin; Han, Juhyeong; Lee, Jung Weon; Seong, Je Kyung; Lee, Yun-Hee

Year: 2024

Venue: Seoul National University

DOI: https://hdl.handle.net/10371/205640

Thesis Investigating the Effect of NMNAT1 Overexpression on Skeletal Muscle Physiology and Metabolism

Samsudeen, Azrah · 2022 · UNSW Sydney · DOI

Full title: Investigating the Effect of NMNAT1 Overexpression on Skeletal Muscle Physiology and Metabolism

Authors: Samsudeen, Azrah

Year: 2022

Venue: UNSW Sydney

DOI: http://hdl.handle.net/1959.4/100275

Thesis Multi-omics analysis of longevity and age-associated changes in axenically cultured Caenorhabditis elegans

Wu, Ping · 2024 · Ghent University (Universiteit Gent) · DOI

Full title: Multi-omics analysis of longevity and age-associated changes in axenically cultured Caenorhabditis elegans

Authors: Wu, Ping

Year: 2024

Venue: Ghent University (Universiteit Gent)

DOI: https://biblio.ugent.be/publication/01JAFT9PTSESWWMZ89PKPDE170

Thesis Influence of blue light irradiation on endothelial cells and weighted gene co-expression network analysis in the development of abdominal aortic aneurysm

Kan, Kejia · 2022 · Heidelberg University · DOI

Full title: Influence of blue light irradiation on endothelial cells and weighted gene co-expression network analysis in the development of abdominal aortic aneurysm

Authors: Kan, Kejia

Year: 2022

Venue: Heidelberg University

DOI: https://archiv.ub.uni-heidelberg.de/volltextserver/31367/1/2006Thesis%20formatted%20Kejia.pdf

Thesis Cytoprotective Pathways that Contribute to Lifespan Extension in C. elegans

Shore, David · 2013 · Harvard University - DASH · DOI

Full title: Cytoprotective Pathways that Contribute to Lifespan Extension in C. elegans

Authors: Shore, David

Year: 2013

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:10270

Thesis Screening the Human Genome for New Mitochondrial and Longevity Regulators

Ling, Alvin Jee Yee · 2015 · Harvard University - DASH · DOI

Full title: Screening the Human Genome for New Mitochondrial and Longevity Regulators

Authors: Ling, Alvin Jee Yee

Year: 2015

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467501

Thesis Emerging strategies for biological age reversal

Zhang, Bohan · 2022 · Harvard University - DASH · DOI

Full title: Emerging strategies for biological age reversal

Authors: Zhang, Bohan

Year: 2022

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372072

Thesis The Role of SIRT1 in Preventing Mitochondrial Dysfunction with Obesity and Aging

Price, Nathan Loftus · 2013 · Harvard University - DASH · DOI

Full title: The Role of SIRT1 in Preventing Mitochondrial Dysfunction with Obesity and Aging

Authors: Price, Nathan Loftus

Year: 2013

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:10363

Thesis Dietary Restriction-Induced Longevity in Caenorhabditis elegans: Mediated by Stress Defense, NAD$^+$-Dependent Mechanisms and a Respiratory Shift

Karagodsky, Natalie · 2014 · Harvard University - DASH · DOI

Full title: Dietary Restriction-Induced Longevity in Caenorhabditis elegans: Mediated by Stress Defense, NAD$^+$-Dependent Mechanisms and a Respiratory Shift

Authors: Karagodsky, Natalie

Year: 2014

Venue: Harvard University - DASH

DOI: http://dissertations.umi.com/gsas.harvard:11651

Thesis The role of RNA splicing factors in the regulation of longevity

Dutta, Sneha · 2021 · Harvard University - DASH · DOI

Full title: The role of RNA splicing factors in the regulation of longevity

Authors: Dutta, Sneha

Year: 2021

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37370115

Thesis Improving metabolic health via dietary and pharmacologic modulation of stress response pathways

MacArthur, Michael Robert · 2021 · Harvard University - DASH · DOI

Full title: Improving metabolic health via dietary and pharmacologic modulation of stress response pathways

Authors: MacArthur, Michael Robert

Year: 2021

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368922

Thesis Bioinformatic and molecular study of the regulation of SIRT3 expression

Satterstrom, F. Kyle Kyle · 2015 · Harvard University - DASH · DOI

Full title: Bioinformatic and molecular study of the regulation of SIRT3 expression

Authors: Satterstrom, F. Kyle Kyle

Year: 2015

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226041

Thesis Ancient metabolic switches underpinning organismal longevity

Ahsan, Fasih Mubtasim · 2025 · Harvard University - DASH · DOI

Full title: Ancient metabolic switches underpinning organismal longevity

Authors: Ahsan, Fasih Mubtasim

Year: 2025

Venue: Harvard University - DASH

DOI: https://dash.harvard.edu/handle/1/42719443

Thesis Mechanisms and Effects of NAD+ Modulation in Inflammation and Aging

Schultz, Michael B. · 2019 · Harvard University - DASH · DOI

Full title: Mechanisms and Effects of NAD+ Modulation in Inflammation and Aging

Authors: Schultz, Michael B.

Year: 2019

Venue: Harvard University - DASH

DOI: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42029714

Thesis Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Griffin, Patrick T · 2023 · Harvard University - DASH · DOI

Full title: Improved methods for age, frailty, and mortality prediction in large-scale longevity studies

Authors: Griffin, Patrick T

Year: 2023

Venue: Harvard University - DASH

DOI: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37375515

Thesis Targeting mTORC1 in the neurons to promote healthy aging in C. elegans

Smith, Hannah Josephine · 2025 · Harvard University - DASH · DOI

Full title: Targeting mTORC1 in the neurons to promote healthy aging in C. elegans

Authors: Smith, Hannah Josephine

Year: 2025

Venue: Harvard University - DASH

DOI: https://dash.harvard.edu/handle/1/42719604

Thesis Effect of intermittent fasting and meal timing on metabolic health

Liu, Kai · 2023 · University of Adelaide · DOI

Full title: Effect of intermittent fasting and meal timing on metabolic health

Authors: Liu, Kai

Year: 2023

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/138982

Thesis Role of nutritional intervention on metabolic health and autophagy

Chaudhary, Rajesh · 2021 · University of Adelaide · DOI

Full title: Role of nutritional intervention on metabolic health and autophagy

Authors: Chaudhary, Rajesh

Year: 2021

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/133308

Thesis Mitophagy Transcriptome: Mechanistic Insights into Polyphenol-Mediated Mitophagy

Tan, Sijie; Wong, Esther · 2017 · Nanyang Technological University (NTU) · DOI

Full title: Mitophagy Transcriptome: Mechanistic Insights into Polyphenol-Mediated Mitophagy

Authors: Tan, Sijie; Wong, Esther

Year: 2017

Venue: Nanyang Technological University (NTU)

DOI: https://hdl.handle.net/10356/84065

Thesis Intermittent Fasting Versus Calorie Restriction to Reduce Risk of Type 2 Diabetes

Teong, Xiao Tong · 2022 · University of Adelaide · DOI

Full title: Intermittent Fasting Versus Calorie Restriction to Reduce Risk of Type 2 Diabetes

Authors: Teong, Xiao Tong

Year: 2022

Venue: University of Adelaide

DOI: https://hdl.handle.net/2440/138233

Thesis Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.

Ling, Catriona; Versloot, Christian J; Arvidsson Kvissberg, Matilda E et al. · 2023 · Utrecht University · DOI

Full title: Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.

Authors: Ling, Catriona; Versloot, Christian J; Arvidsson Kvissberg, Matilda E; Hu, Guanlan; Swain, Nathan; Horcas-Nieto, José M; Miraglia, Emily; Thind, Mehakpreet K; Farooqui, Amber; Gerding, Albert; van Eunen, Karen; Koster, Mirjam H; Kloosterhuis, Niels J; Chi, Lijun; ChenMi, YueYing; Langelaar-Makkinje, Miriam; Bourdon, Celine; Swann, Jonathan; Smit, Marieke; de Bruin, Alain; Youssef, Sameh A; Feenstra, Marjon; van Dijk, Theo H; Thedieck, Kathrin; Jonker, Johan W; Kim, Peter K; Bakker, Barbara M; Bandsma, Robert H J

Year: 2023

Venue: Utrecht University

DOI: https://dspace.library.uu.nl/handle/1874/432243

Thesis Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways

Carr, Christopher E.; Shore, David E.; Ruvkin, Gary · 2012 · Massachusetts Institute of Technology (MIT) · DOI

Full title: Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways

Authors: Carr, Christopher E.; Shore, David E.; Ruvkin, Gary

Year: 2012

Venue: Massachusetts Institute of Technology (MIT)

DOI: http://hdl.handle.net/1721.1/74620

Thesis Investigating Metabolism-Based Pharmacologic and Dietary Strategies of Nutrient Restriction to Impact Health and Disease

Allen, Annamarie · 2023 · Duke University · DOI

Full title: Investigating Metabolism-Based Pharmacologic and Dietary Strategies of Nutrient Restriction to Impact Health and Disease

Authors: Allen, Annamarie

Year: 2023

Venue: Duke University

DOI: https://hdl.handle.net/10161/26821

Thesis Dietary mitophagy enhancer: A strategy for healthy brain aging?

Varghese, Nimmy; Werner, Selina; Grimm, Amandine et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Dietary mitophagy enhancer: A strategy for healthy brain aging?

Authors: Varghese, Nimmy; Werner, Selina; Grimm, Amandine; Eckert, Anne

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/46090

Thesis The protective effects of hyperbaric oxygen on ionising radiation injury: A systematic review

Holyer, Amanda; Stewart, Thomas; Ashworth, Edward T. · 2025 · University of Basel - edoc Repository · DOI

Full title: The protective effects of hyperbaric oxygen on ionising radiation injury: A systematic review

Authors: Holyer, Amanda; Stewart, Thomas; Ashworth, Edward T.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: https://hdl.handle.net/20.500.14716/202767

Thesis Impact papers on aging in 2009

Blagosklonny, M. V.; Campisi, J.; Sinclair, D. A. et al. · 2025 · University of Basel - edoc Repository · DOI

Full title: Impact papers on aging in 2009

Authors: Blagosklonny, M. V.; Campisi, J.; Sinclair, D. A.; Bartke, A.; Blasco, M. A.; Bonner, W. M.; Bohr, V. A.; Brosh, R. M.; Brunet, A.; Depinho, R. A.; Donehower, L. A.; Finch, C. E.; Finkel, T.; Gorospe, M.; Gudkov, A. V.; Hall, M. N.; Hekimi, S.; Helfand, S. L.; Karlseder, J.; Kenyon, C.; Kroemer, G.; Longo, V.; Nussenzweig, A.; Osiewacz, H. D.; Peeper, D. S.; Rando, T. A.; Rudolph, K. L.; Sassone-Corsi, P.; Serrano, M.; Sharpless, N. E.; Skulachev, V. P.; Tilly, J. L.; Tower, J.; Verdin, E.; Vijg, J.

Year: 2025

Venue: University of Basel - edoc Repository

DOI: http://hdl.handle.net/20.500.14716/79765

Thesis Immune-metabolic Regulation by the Transsulfuration Pathway

Lee, Aileen Heeyeon · 2021 · Yale University · DOI

Full title: Immune-metabolic Regulation by the Transsulfuration Pathway

Authors: Lee, Aileen Heeyeon

Year: 2021

Venue: Yale University

DOI: https://elischolar.library.yale.edu/gsas_dissertations/75

Thesis Advancing Mitochondrial Therapeutics Drug Discovery for Healthy Aging

Phang, Howard John · 2025 · University of California, San Diego (UCSD) · DOI

Full title: Advancing Mitochondrial Therapeutics Drug Discovery for Healthy Aging

Authors: Phang, Howard John

Year: 2025

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/0r6454tv

Thesis Mapping Cell-Fate Choices in A549 Cells under DNA Damage and Metabolic Stress

Sarath Chandran, Aathira · 2025 · University of California, San Diego (UCSD) · DOI

Full title: Mapping Cell-Fate Choices in A549 Cells under DNA Damage and Metabolic Stress

Authors: Sarath Chandran, Aathira

Year: 2025

Venue: University of California, San Diego (UCSD)

DOI: https://escholarship.org/uc/item/04q685td

Thesis Do sex and age influence the metabolic and cardiovascular consequences of caloric restriction?

Thomas, Benjamin James · 2022 · The University of Edinburgh · DOI

Full title: Do sex and age influence the metabolic and cardiovascular consequences of caloric restriction?

Authors: Thomas, Benjamin James

Year: 2022

Venue: The University of Edinburgh

DOI: https://hdl.handle.net/1842/39538

Thesis The Effect of Time-restricted Eating on Metabolic Health

Zhu, Shengjie · 2025 · University of California, Davis · DOI

Full title: The Effect of Time-restricted Eating on Metabolic Health

Authors: Zhu, Shengjie

Year: 2025

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/1wt285fm

Thesis The effects of a short-term (1-week) very low-calorie diet (850 calories) comparing low and normal protein content on cardiometabolic outcomes, glucose metabolism and autophagy

Burns, Lucy · 2025 · University of Nottingham · DOI

Full title: The effects of a short-term (1-week) very low-calorie diet (850 calories) comparing low and normal protein content on cardiometabolic outcomes, glucose metabolism and autophagy

Authors: Burns, Lucy

Year: 2025

Venue: University of Nottingham

DOI: https://eprints.nottingham.ac.uk/80239/1/Thesis%20amendments%20-%20unhighlighted.pdf

Thesis Exploring the effects of dietary restriction and macronutrient composition on life-history traits, in a non-model vertebrate system

Moatt, Joshua Philip · 2018 · The University of Edinburgh · DOI

Full title: Exploring the effects of dietary restriction and macronutrient composition on life-history traits, in a non-model vertebrate system

Authors: Moatt, Joshua Philip

Year: 2018

Venue: The University of Edinburgh

DOI: http://hdl.handle.net/1842/31076

Thesis Effects of Anti-Aging Interventions on the Mouse Metabolome

Greenfield, Sara Marie · 2024 · University of California, Davis · DOI

Full title: Effects of Anti-Aging Interventions on the Mouse Metabolome

Authors: Greenfield, Sara Marie

Year: 2024

Venue: University of California, Davis

DOI: https://escholarship.org/uc/item/0xs8g20k

Thesis In vivo characterisation of Zoledronate, a drug which delays or reverses tissue ageing.

Chen, Zhengqi · 2020 · White Rose eTheses (Leeds, Sheffield, York) · DOI

Full title: In vivo characterisation of Zoledronate, a drug which delays or reverses tissue ageing.

Authors: Chen, Zhengqi

Year: 2020

Venue: White Rose eTheses (Leeds, Sheffield, York)

DOI: https://etheses.whiterose.ac.uk/id/eprint/27792/1/Zhengqi%20Chen_%20Thesis_%20%E4%BF%AE%E6%94%B9%E7%89%88.docx

Thesis Impact of Rapamycin on Genome Organization

Pickering, Josh AD 1988- · 2018 · University of Saskatchewan - HARVEST · DOI

Full title: Impact of Rapamycin on Genome Organization

Authors: Pickering, Josh AD 1988-

Year: 2018

Venue: University of Saskatchewan - HARVEST

DOI: http://hdl.handle.net/10388/11672

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Longevity, aging and rapamycin

Ehninger, Dan; Neff, Frauke; Xie, Kan · 2014

Full title: Longevity, aging and rapamycin

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Full title: Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill.

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Full title: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

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Full title: Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

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Full title: Considerations Regarding Public Use of Longevity Interventions.

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Full title: Premature aging in genetic diseases: what conclusions can be drawn for physiological aging

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Full title: Toward precision longevity: aging interventions in the single-cell atlas era.

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Full title: Life Extension by Anti-Aging Drugs: Hormetic Explanation?

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Full title: Anti-aging strategies for dogs: current insights and future directions

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Cady, Gillian; Sadagurski, Marianna · 2017

Full title: Targeting neuroinflammation - a potential for anti-aging interventions.

Authors: Cady, Gillian; Sadagurski, Marianna

DOI: https://doi.org/10.18632/aging.101296

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Inflammaging: disturbed interplay between autophagy and inflammasomes

Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu · 2012

Full title: Inflammaging: disturbed interplay between autophagy and inflammasomes

Authors: Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu

DOI: https://doi.org/10.18632/aging.100444

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New comparative genomics approach reveals a conserved health span signature across species

Antosh, Michael; Fox, David J.; Helfand, Stephen L. et al. · 2011

Full title: New comparative genomics approach reveals a conserved health span signature across species

Authors: Antosh, Michael; Fox, David J.; Helfand, Stephen L.; Cooper, Leon N.; Neretti, Nicola

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Fish oil supplements, longevity and aging.

de Magalhães, João Pedro; Müller, Michael; Rainger, G Ed et al. · 2016

Full title: Fish oil supplements, longevity and aging.

Authors: de Magalhães, João Pedro; Müller, Michael; Rainger, G Ed; Steegenga, Wilma

DOI: https://doi.org/10.18632/aging.101021

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A review of the biomedical innovations for healthy longevity

A. Moskalev; V. Anisimov; A. Aliper et al. · 2017

Full title: A review of the biomedical innovations for healthy longevity

DOI: https://doi.org/10.18632/aging.101163

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Fasting for stem cell rejuvenation

Cristina González-Estévez; I. Flores · 2020

Full title: Fasting for stem cell rejuvenation

Authors: Cristina González-Estévez; I. Flores

DOI: https://doi.org/10.18632/aging.102912

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It is necessary to establish an International Agency for Research on Aging.

Anisimov, Vladimir N; Sidorenko, Alexandre V · 2018

Full title: It is necessary to establish an International Agency for Research on Aging.

Authors: Anisimov, Vladimir N; Sidorenko, Alexandre V

DOI: https://doi.org/10.18632/aging.101451

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Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.

Moskalev, Alexey; Chernyagina, Elizaveta; de Magalhães, João Pedro et al. · 2015

Full title: Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.

DOI: https://doi.org/10.18632/aging.100799

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Latest advances in aging research and drug discovery

Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano et al. · 2019

Full title: Latest advances in aging research and drug discovery

DOI: https://doi.org/10.18632/aging.102487

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Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 Drosophila species with different lifespans

M. Shaposhnikov; N. Zemskaya; Liubov A. Koval et al. · 2018

Full title: Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 Drosophila species with different lifespans

Authors: M. Shaposhnikov; N. Zemskaya; Liubov A. Koval; E. V. Schegoleva; A. Zhavoronkov; A. Moskalev

DOI: https://doi.org/10.18632/aging.101561

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Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori

Jiangbo Song; Guihua Jiang; Jianfei Zhang et al. · 2019

Full title: Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori

Authors: Jiangbo Song; Guihua Jiang; Jianfei Zhang; Jie-Shu Guo; Zheng Li; Kaige Hao; Lian X Liu; Z. Cheng; X. Tong; F. Dai

DOI: https://doi.org/10.18632/aging.101746

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Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?

Skulachev, Vladimir P; Shilovsky, Gregory A; Putyatina, Tatyana S et al. · 2020

Full title: Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?

Authors: Skulachev, Vladimir P; Shilovsky, Gregory A; Putyatina, Tatyana S; Popov, Nikita A; Markov, Alexander V; Skulachev, Maxim V; Sadovnichii, Victor A

DOI: https://doi.org/10.18632/aging.102981

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Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion.

Bartke, Andrzej; Evans, Tracy R; Musters, C J M · 2019

Full title: Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion.

Authors: Bartke, Andrzej; Evans, Tracy R; Musters, C J M

DOI: https://doi.org/10.18632/aging.102037

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A multi-tissue full lifespan epigenetic clock for mice.

Thompson, Michael J; Chwiałkowska, Karolina; Rubbi, Liudmilla et al. · 2018

Full title: A multi-tissue full lifespan epigenetic clock for mice.

Authors: Thompson, Michael J; Chwiałkowska, Karolina; Rubbi, Liudmilla; Lusis, Aldons J; Davis, Richard C; Srivastava, Anuj; Korstanje, Ron; Churchill, Gary A; Horvath, Steve; Pellegrini, Matteo

DOI: https://doi.org/10.18632/aging.101590

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From causes of aging to death from COVID-19.

Blagosklonny, Mikhail V · 2020

Full title: From causes of aging to death from COVID-19.

Authors: Blagosklonny, Mikhail V

DOI: https://doi.org/10.18632/aging.103493

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Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

Demidenko, Oleksandr; Barardo, Diogo; Budovskii, Valery et al. · 2021

Authors: Demidenko, Oleksandr; Barardo, Diogo; Budovskii, Valery; Finnemore, Robb; Palmer, Francis R.; Kennedy, Brian K.; Budovskaya, Yelena V.

DOI: https://doi.org/10.18632/aging.203736

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Geroprotective effects of Alzheimer's disease drug candidates.

Kepchia, Devin; Currais, Antonio; Dargusch, Richard et al. · 2021

Full title: Geroprotective effects of Alzheimer's disease drug candidates.

Authors: Kepchia, Devin; Currais, Antonio; Dargusch, Richard; Finley, Kim; Schubert, David; Maher, Pamela

DOI: https://doi.org/10.18632/aging.202631

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When aging switches on Alzheimer’s

Yue Dong; Benjamin Harlan; G. Brewer · 2021

Full title: When aging switches on Alzheimer’s

Authors: Yue Dong; Benjamin Harlan; G. Brewer

DOI: https://doi.org/10.18632/aging.203085

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Meeting Report: Aging Research and Drug Discovery

Meron, Esther; Thaysen, Maria; Angeli, Suzanne et al. · 2022

Full title: Meeting Report: Aging Research and Drug Discovery

DOI: https://doi.org/10.18632/aging.203859

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Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.

Zhavoronkov, Alex · 2020

Full title: Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.

Authors: Zhavoronkov, Alex

DOI: https://doi.org/10.18632/aging.102988

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Predicting physiological aging rates from a range of quantitative traits using machine learning

Sun, Eric; Qian, Yong; Oppong, Richard et al. · 2021

Full title: Predicting physiological aging rates from a range of quantitative traits using machine learning

DOI: https://doi.org/10.18632/aging.203660

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Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.

Al-Mansour, Fares; Alraddadi, Abdullah; He, Buwei et al. · 2023

Full title: Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.

Authors: Al-Mansour, Fares; Alraddadi, Abdullah; He, Buwei; Saleh, Anes; Poblocka, Marta; Alzahrani, Wael; Cowley, Shaun; Macip, Salvador

DOI: https://doi.org/10.18632/aging.204616

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Senolytic effect of high intensity interval exercise on human skeletal muscle.

Jean, Wei-Horng; Hsieh, Yu-Wen; Lai, Li-Fan et al. · 2023

Full title: Senolytic effect of high intensity interval exercise on human skeletal muscle.

Authors: Jean, Wei-Horng; Hsieh, Yu-Wen; Lai, Li-Fan; Dewi, Luthfia; Liao, Yu-Chieh; Ye, Mengxin; Yu, Szu-Hsien; Kao, Chung-Lan; Huang, Chih-Yang; Kuo, Chia-Hua

DOI: https://doi.org/10.18632/aging.204511

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Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

Barzilai, David · 2025

Full title: Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

Authors: Barzilai, David

DOI: https://doi.org/10.18632/aging.206189

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Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B. · 2024

Full title: Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Authors: Bertucci, Emily M.; Shealy, Ethan P.; Parrott, Benjamin B.

DOI: https://doi.org/10.18632/aging.205503

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Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

Blagosklonny, Mikhail V. · 2023

Full title: Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

Authors: Blagosklonny, Mikhail V.

DOI: https://doi.org/10.18632/aging.204920

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The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.

Banse, Stephen A; Jackson, E Grace; Sedore, Christine A et al. · 2024

Full title: The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.

DOI: https://doi.org/10.18632/aging.205743

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Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions.

Lee, Edwin; Carreras-Gallo, Natàlia; Lopez, Leilani et al. · 2024

Full title: Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions.

DOI: https://doi.org/10.18632/aging.205581

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Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial.

Carreras-Gallo, Natalia; Dargham, Rita; Thorpe, Shealee P et al. · 2025

Full title: Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial.

Authors: Carreras-Gallo, Natalia; Dargham, Rita; Thorpe, Shealee P; Warren, Steve; Mendez, Tavis L; Smith, Ryan; Macpherson, Greg; Dwaraka, Varun B

DOI: https://doi.org/10.18632/aging.206221

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Role of growth differentiation factor 11 in development, physiology and disease

Zhang, Yonghui; Wei, Yong; Liu, Dan et al. · 2017

Full title: Role of growth differentiation factor 11 in development, physiology and disease

Authors: Zhang, Yonghui; Wei, Yong; Liu, Dan; Liu, Feng; Li, Xiaoshan; Pan, Lianhong; Pang, Yi; Chen, Dilong

DOI: https://doi.org/10.18632/oncotarget.20258

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Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors.

Mohammad, Karamat; Titorenko, Vladimir I · 2021

Full title: Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors.

Authors: Mohammad, Karamat; Titorenko, Vladimir I

DOI: https://doi.org/10.18632/oncotarget.27926

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Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Sousa‐Victor, Pedro; García‐Prat, Laura; Muñoz‐Cánoves, Pura · 2015

Full title: Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Authors: Sousa‐Victor, Pedro; García‐Prat, Laura; Muñoz‐Cánoves, Pura

DOI: https://doi.org/10.18632/oncotarget.5563

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Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast.

Mohammad, Karamat; Orfanos, Emmanuel; Titorenko, Vladimir I · 2021

Full title: Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast.

Authors: Mohammad, Karamat; Orfanos, Emmanuel; Titorenko, Vladimir I

DOI: https://doi.org/10.18632/oncotarget.28133

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Epigenetic dysregulation in cardiovascular aging and disease.

Herman, Allison B; Occean, James R; Sen, Payel · 2021

Full title: Epigenetic dysregulation in cardiovascular aging and disease.

Authors: Herman, Allison B; Occean, James R; Sen, Payel

DOI: https://doi.org/10.20517/jca.2021.16

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Gut microbiota: an ideal biomarker and intervention strategy for aging.

Xu, Xuan; Xu, Tangchang; Wei, Jing et al. · 2024

Full title: Gut microbiota: an ideal biomarker and intervention strategy for aging.

Authors: Xu, Xuan; Xu, Tangchang; Wei, Jing; Chen, Tingtao

DOI: https://doi.org/10.20517/mrr.2023.68

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Does Modulation of an Epigenetic Clock Define a Geroprotector?

Schork, Nicholas J; Beaulieu-Jones, Brett; Liang, Winnie et al. · 2022

Full title: Does Modulation of an Epigenetic Clock Define a Geroprotector?

Authors: Schork, Nicholas J; Beaulieu-Jones, Brett; Liang, Winnie; Smalley, Susan; Goetz, Laura H

DOI: https://doi.org/10.20900/agmr20220002

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Modulation of Endocannabinoids by Caloric Restriction is Conserved in Mice but is not Required for the Protection from Acute Kidney Injury

Hoyer-Allo, Karla Johanna Ruth; Späth, Martin R.; Hanßen, Ruth et al. · 2021

Full title: Modulation of Endocannabinoids by Caloric Restriction is Conserved in Mice but is not Required for the Protection from Acute Kidney Injury

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Editorial: DNA repair and interventions in aging

Brosh, Robert M.; Moskalev, Alexey; Gorbunova, Vera · 2023

Full title: Editorial: DNA repair and interventions in aging

Authors: Brosh, Robert M.; Moskalev, Alexey; Gorbunova, Vera

DOI: https://doi.org/10.3389/fragi.2023.1306463

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Exploring juventology: unlocking the secrets of youthspan and longevity programs

Brandhorst, Sebastian; Longo, Valter D. · 2024

Full title: Exploring juventology: unlocking the secrets of youthspan and longevity programs

Authors: Brandhorst, Sebastian; Longo, Valter D.

DOI: https://doi.org/10.3389/fragi.2024.1379289

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Sirolimus use in allogeneic hematopoietic cell transplant recipients: assessing its senotherapeutic role in a high risk population

Najla El Jurdi; Heba Elhusseini; Qing Cao et al. · 2025

Full title: Sirolimus use in allogeneic hematopoietic cell transplant recipients: assessing its senotherapeutic role in a high risk population

Authors: Najla El Jurdi; Heba Elhusseini; Qing Cao; Thomas Klinger; Ella Shapiro; Melike Cömert; M. Juckett; S. Holtan; Matthew J. Yousefzadeh

DOI: https://doi.org/10.3389/fragi.2025.1673230

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Geroscience and pathology: a new frontier in understanding age-related diseases.

Fekete, Monika; Major, David; Feher, Agnes et al. · 2024

Full title: Geroscience and pathology: a new frontier in understanding age-related diseases.

Authors: Fekete, Monika; Major, David; Feher, Agnes; Fazekas-Pongor, Vince; Lehoczki, Andrea

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Therapeutic Antiaging Strategies

Mishra, Shailendra Kumar; Balendra, Vyshnavy; Esposto, Josephine et al. · 2022

Full title: Therapeutic Antiaging Strategies

DOI: https://doi.org/10.3390/biomedicines10102515

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Influence of Adipokines on Metabolic Dysfunction and Aging.

Park, Seongjoon; Shimokawa, Isao · 2024

Full title: Influence of Adipokines on Metabolic Dysfunction and Aging.

Authors: Park, Seongjoon; Shimokawa, Isao

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New Trends in Aging Drug Discovery

B. Benhamú; M. Martín-Fontecha; Henar Vázquez-Villa et al. · 2022

Full title: New Trends in Aging Drug Discovery

Authors: B. Benhamú; M. Martín-Fontecha; Henar Vázquez-Villa; M. López-Rodríguez; S. Ortega‐Gutiérrez

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Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging

Yu, Mengdi; Zhang, Hongxia; Wang, Brian et al. · 2021

Full title: Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging

Authors: Yu, Mengdi; Zhang, Hongxia; Wang, Brian; Zhang, Yinuo; Zheng, Xiaoying; Shao, Bei; Zhuge, Qichuan; Jin, Kunlin

DOI: https://doi.org/10.3390/cells10030660

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Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

Statsenko, Yauhen; Kuznetsov, Nikolai V.; Morozova, Daria et al. · 2023

Full title: Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond

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Senescent Cells: Dual Implications on the Retinal Vascular System

Mohammad Reza Habibi-Kavashkohie; T. Scorza; Malika Oubaha · 2023

Full title: Senescent Cells: Dual Implications on the Retinal Vascular System

Authors: Mohammad Reza Habibi-Kavashkohie; T. Scorza; Malika Oubaha

DOI: https://doi.org/10.3390/cells12192341

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Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice

McGill, Cassandra; Christensen, Amy; Qian, Wenjie et al. · 2024

Full title: Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice

Authors: McGill, Cassandra; Christensen, Amy; Qian, Wenjie; Thorwald, Max A.; Lugo, Jose Godoy; Namvari, Sara; White, Olivia S.; Finch, Caleb E.; Benayoun, Bérénice A.; Pike, Christian J.

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Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Guelfi, Gabriella; Capaccia, Camilla; Tedeschi, Martina et al. · 2024

Full title: Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Authors: Guelfi, Gabriella; Capaccia, Camilla; Tedeschi, Martina; Bufalari, Antonello; Leonardi, Leonardo; Cenci‐Goga, Beniamino T.; Maranesi, Margherita

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Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones.

Bramwell, Laura R; Frankum, Ryan; Harries, Lorna W · 2024

Full title: Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones.

Authors: Bramwell, Laura R; Frankum, Ryan; Harries, Lorna W

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Assessment of Pullulan, a Microbial Polysaccharide, as a Matrix for Senotherapeutics Delivery

Ramona-Daniela Păvăloiu; Fawzia Sha’at; Corina Bubueanu et al. · 2023

Full title: Assessment of Pullulan, a Microbial Polysaccharide, as a Matrix for Senotherapeutics Delivery

Authors: Ramona-Daniela Păvăloiu; Fawzia Sha’at; Corina Bubueanu; M. Petrescu; Claudia Sevcenco

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Molecular Regulation of SASP in Cellular Senescence: Therapeutic Implications and Translational Challenges.

Klepacki, Hubert; Kowalczuk, Krystyna; Łepkowska, Natalia et al. · 2025

Full title: Molecular Regulation of SASP in Cellular Senescence: Therapeutic Implications and Translational Challenges.

Authors: Klepacki, Hubert; Kowalczuk, Krystyna; Łepkowska, Natalia; Hermanowicz, Justyna Magdalena

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Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions

Yan, Bowen; Yuan, Qingchen; Guryanova, Olga A. · 2023

Full title: Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions

Authors: Yan, Bowen; Yuan, Qingchen; Guryanova, Olga A.

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The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Bjedov, Ivana; Rallis, Charalampos · 2020

Full title: The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Authors: Bjedov, Ivana; Rallis, Charalampos

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The Role of Ghrelin and Ghrelin Signaling in Aging

Amitani, Marie; Amitani, Haruka; Cheng, Kai‐Chun et al. · 2017

Full title: The Role of Ghrelin and Ghrelin Signaling in Aging

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Longevity: Lesson from Model Organisms.

Taormina, Giusi; Ferrante, Federica; Vieni, Salvatore et al. · 2019

Full title: Longevity: Lesson from Model Organisms.

Authors: Taormina, Giusi; Ferrante, Federica; Vieni, Salvatore; Grassi, Nello; Russo, Antonio; Mirisola, Mario G

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Treating Senescence like Cancer: Novel Perspectives in Senotherapy of Chronic Diseases.

Mongelli, Alessia; Atlante, Sandra; Barbi, Veronica et al. · 2020

Full title: Treating Senescence like Cancer: Novel Perspectives in Senotherapy of Chronic Diseases.

Authors: Mongelli, Alessia; Atlante, Sandra; Barbi, Veronica; Bachetti, Tiziana; Martelli, Fabio; Farsetti, Antonella; Gaetano, Carlo

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Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury

Hoyer-Allo, Karla Johanna Ruth; Späth, Martin R.; Hanßen, Ruth et al. · 2021

Full title: Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury

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Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue

Kobayashi, Masaki; Deguchi, Yusuke; Nozaki, Yuka et al. · 2021

Full title: Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue

Authors: Kobayashi, Masaki; Deguchi, Yusuke; Nozaki, Yuka; Higami, Yoshikazu

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The Impact of Caloric Restriction on the Epigenetic Signatures of Aging

Noémie Gensous; C. Franceschi; A. Santoro et al. · 2019

Full title: The Impact of Caloric Restriction on the Epigenetic Signatures of Aging

Authors: Noémie Gensous; C. Franceschi; A. Santoro; M. Milazzo; P. Garagnani; M. Bacalini

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Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

M. Jové; R. Cabré; N. Mota-Martorell et al. · 2021

Full title: Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

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Mitochondrial Aging and Senolytic Natural Products with Protective Potential.

Deledda, Andrea; Giordano, Emanuele; Velluzzi, Fernanda et al. · 2022

Full title: Mitochondrial Aging and Senolytic Natural Products with Protective Potential.

Authors: Deledda, Andrea; Giordano, Emanuele; Velluzzi, Fernanda; Flore, Giovanna; Franceschelli, Sara; Speranza, Lorenza; Ripari, Patrizio

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Cellular senescence: a key therapeutic target in aging and diseases.

Zhang, Lei; Pitcher, Louise E; Yousefzadeh, Matthew J et al. · 2022

Full title: Cellular senescence: a key therapeutic target in aging and diseases.

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Rapamycin extends murine lifespan but has limited effects on aging

Neff, Frauke; Flores-Dominguez, Diana; Ryan, Devon et al. · 2013

Full title: Rapamycin extends murine lifespan but has limited effects on aging

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Diminished mTOR signaling: a common mode of action for endocrine longevity factors

Lamming, Dudley W. · 2014

Full title: Diminished mTOR signaling: a common mode of action for endocrine longevity factors

Authors: Lamming, Dudley W.

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Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.

Sutphin, George L; Bishop, Emma; Yanos, Melana E et al. · 2012

Full title: Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.

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Xu, X.Z. Shawn; Zhan, Ming; Duan, Wenzhen et al. · 2007

Full title: Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender

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Geroprotector drugs and exercise: friends or foes on healthy longevity?

Elliehausen, Christian J; Anderson, Rozalyn M; Diffee, Gary M et al. · 2023

Full title: Geroprotector drugs and exercise: friends or foes on healthy longevity?

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Fifteen years of progress in understanding frailty and health in aging

Rockwood, Kenneth; Howlett, Susan E. · 2018

Full title: Fifteen years of progress in understanding frailty and health in aging

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Full title: Sex-specific insights into drug-induced lifespan extension and weight loss in mice

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Full title: The senolytic drug ABT-263 accelerates ovarian aging in older female mice.

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Full title: Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.

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Full title: The Potential of Calorie Restriction and Calorie Restriction Mimetics in Delaying Aging: Focus on Experimental Models.

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Full title: Researching New Drug Combinations with Senolytic Activity Using Senescent Human Lung Fibroblasts MRC-5 Cell Line

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Senolytics and Dietary Phytochemicals: Exploring Anti-Aging Strategies and Mechanisms in Aging and Disease

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Full title: Determinants of human longevity: input of environment, nutrition, physical activity, eustress, heredity, health care, motivation, and mental state

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Full title: Novel feature selection methods for construction of accurate epigenetic clocks.

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Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

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Full title: Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

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Wuttke, Daniel; Connor, Richard A.; Vora, Chintan et al. · 2012

Full title: Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes

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Full title: Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

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Zainabadi, Kayvan; Liu, Cassie J.; Guarente, Leonard · 2017

Full title: SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2

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Stress Resistance and Longevity Are Not Directly Linked to Levels of Enzymatic Antioxidants in the Ponerine Ant Harpegnathos saltator

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Full title: Stress Resistance and Longevity Are Not Directly Linked to Levels of Enzymatic Antioxidants in the Ponerine Ant Harpegnathos saltator

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Full title: Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice

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Stambler, Ilia · 2015

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Liebich, Alina; Zheng, Shenglin; Schachner, Theresa et al. · 2024

Full title: Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

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Full title: Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions.

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Full title: Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

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Full title: Synergistic pharmacological interventions and lifestyle modifications to decelerate aging: Targeting cellular senescence and metabolic pathways for longevity

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Full title: Unexpected Increase in Bone Mineral Density With Rapamycin and Low-Dose Naltrexone: A Case Report of a 52-Year-Old Woman With Osteopenia

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Current Research On Epigenetic Age and Cellular Senescence: A Bibliometric and Visual Analysis

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Full title: Current Research On Epigenetic Age and Cellular Senescence: A Bibliometric and Visual Analysis

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Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies

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Full title: Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies

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Full title: Organ specificity and commonality of epigenetic aging in low- and high-running capacity rats

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Full title: Differential Responses of Dynamic and Entropic Aging Factors to Longevity Interventions

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Functional and multi-omic aging rejuvenation with GLP-1R agonism

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Full title: Functional and multi-omic aging rejuvenation with GLP-1R agonism

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DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans

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Full title: DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans

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Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

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Full title: Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan.

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An Open Competition for Biomarkers of Aging.

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Full title: High-dimensional Ageome Representations of Biological Aging across Functional Modules

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Full title: Spatiotemporal profiling reveals the impact of caloric restriction on mammalian brain aging.

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Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

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Full title: Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging

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Full title: A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

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Full title: scAgeClock: a single-cell transcriptome based human aging clock model using gated multi-head attention neural networks

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